CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP016590	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-02, complete sequence	1 crisprs	csa3,cas14j	2	1
NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	0 crisprs	RT,cas14j,csa3	0	4
NZ_CP016588	Bacillus thuringiensis strain KNU-07 chromosome, complete genome	1 crisprs	cas3,DEDDh,c2c9_V-U4,csa3,cas14k,cas14j,WYL,DinG	1	8

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016588_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016588_1

2842294-2842448

Orphan

Consensus_repeat	Method
TAGAACAAAAGGAATGAACATTCATTCCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP016588_1

>merge|NZ_CP016588|1|2842294-2842448|PILER-CR
AAAGGAATGAATATTCATTCCTAAATAGATTTAAAAAATGAGAGTAGGAAAGGATGTTTGTGTAACTAAGGGAATGAACATTCATTCCGGAAAGACTAGTTTAATAGAATTTACAAAATAATGTAATAGAACAATAGGAATGAACGTTCATTCCG

>NZ_CP016588|1|1|2842294-2842448|PILER-CR
AAAGGAATGAATATTCATTCCTAAATAGA	TTTAAAAAATGAGAGTAGGAAAGGATGTTTGTGTAACT
AAGGGAATGAACATTCATTCCGGAAAGAC	TAGTTTAATAGAATTTACAAAATAATGTAATAGAACA
ATAGGAATGAACGTTCATTCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016588.1\|WP_001197238.1\|2836653_2837754_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|134568
NZ_CP016588.1\|WP_001228131.1\|2837746_2838847_+\|prephenate-dehydrogenase	unknown	unknown	gnl\|CDD\|235824
NZ_CP016588.1\|WP_001273575.1\|2834103_2835180_+\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|183614
NZ_CP016588.1\|WP_000664634.1\|2838864_2840154_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_CP016588.1\|WP_000997702.1\|2829174_2829612_-\|YndM-family-protein	unknown	unknown	gnl\|CDD\|371204
NZ_CP016588.1\|WP_000808774.1\|2848068_2850042_+\|LTA-synthase-family-protein	unknown	unknown	gnl\|CDD\|224287
NZ_CP016588.1\|WP_001269429.1\|2835462_2836635_+\|chorismate-synthase	unknown	unknown	gnl\|CDD\|171518
NZ_CP016588.1\|WP_000040300.1\|2842486_2845603_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|225272
NZ_CP016588.1\|WP_001107303.1\|2841708_2842275_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|292911
NZ_CP016588.1\|WP_000346944.1\|2850098_2850773_-\|TerC-family-protein	unknown	unknown	gnl\|CDD\|163429
NZ_CP016588.1\|WP_065703850.1\|2829793_2833276_+\|DUF4020-domain-containing-protein	unknown	unknown	gnl\|CDD\|372518
NZ_CP016588.1\|WP_000633864.1\|2845915_2847541_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
NZ_CP016588.1\|WP_001067270.1\|2852285_2852444_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016588.1\|WP_000923455.1\|2853415_2854099_+\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|132880
NZ_CP016588.1\|WP_001102496.1\|2854832_2855390_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP016588.1\|WP_000551443.1\|2851165_2851993_-\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200569
NZ_CP016588.1\|WP_000800677.1\|2852575_2852965_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|366361
NZ_CP016588.1\|WP_001100934.1\|2840279_2841440_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226925
NZ_CP016588.1\|WP_000643682.1\|2854115_2854817_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143393
NZ_CP016588.1\|WP_000709536.1\|2828494_2829025_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496

Protein	Function_ID	Function_description	E-value
NZ_CP016588.1\|WP_001197238.1\|2836653_2837754_+\|histidinol-phosphate-transaminase	gnl\|CDD\|134568	PRK01533, PRK01533, histidinol-phosphate aminotransferase; Validated.	0
NZ_CP016588.1\|WP_001228131.1\|2837746_2838847_+\|prephenate-dehydrogenase	gnl\|CDD\|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	1.95343e-158
NZ_CP016588.1\|WP_001273575.1\|2834103_2835180_+\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|183614	PRK12595, PRK12595, bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed.	0
NZ_CP016588.1\|WP_000664634.1\|2838864_2840154_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_CP016588.1\|WP_000997702.1\|2829174_2829612_-\|YndM-family-protein	gnl\|CDD\|371204	pfam10710, DUF2512, Protein of unknown function (DUF2512). Proteins in this family are predicted to be integral membrane proteins, and many of them are annotated as being YndM protein. They are all found in Firmicutes. The true function is not known.	8.18943e-46
NZ_CP016588.1\|WP_000808774.1\|2848068_2850042_+\|LTA-synthase-family-protein	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_CP016588.1\|WP_001269429.1\|2835462_2836635_+\|chorismate-synthase	gnl\|CDD\|171518	PRK12463, PRK12463, chorismate synthase; Reviewed.	0
NZ_CP016588.1\|WP_000040300.1\|2842486_2845603_+\|MMPL-family-transporter	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	5.30185e-78
NZ_CP016588.1\|WP_001107303.1\|2841708_2842275_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|292911	pfam16295, TetR_C_10, Tetracycline repressor, C-terminal all-alpha domain.	6.10222e-64
NZ_CP016588.1\|WP_000346944.1\|2850098_2850773_-\|TerC-family-protein	gnl\|CDD\|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	1.84621e-74
NZ_CP016588.1\|WP_065703850.1\|2829793_2833276_+\|DUF4020-domain-containing-protein	gnl\|CDD\|372518	pfam13212, DUF4020, Domain of unknown function (DUF4020). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is typically between 176 and 195 amino acids in length.	3.0654e-73
NZ_CP016588.1\|WP_000633864.1\|2845915_2847541_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP016588.1\|WP_000923455.1\|2853415_2854099_+\|DNA-alkylation-repair-protein	gnl\|CDD\|132880	cd06561, AlkD_like, A new structural DNA glycosylase. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity.	2.15358e-27
NZ_CP016588.1\|WP_001102496.1\|2854832_2855390_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.494e-22
NZ_CP016588.1\|WP_000551443.1\|2851165_2851993_-\|polysaccharide-deacetylase	gnl\|CDD\|200569	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins. This family is represented by a putative polysaccharide deacetylase PgdA from the oral pathogen Streptococcus mutans (SmPgdA) and Bacillus subtilis YheN (BsYheN), which are members of the carbohydrate esterase 4 (CE4) superfamily. SmPgdA is an extracellular metal-dependent polysaccharide deacetylase with a typical CE4 fold, with metal bound to a His-His-Asp triad. It possesses de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. SmPgdA plays a role in tuning cell surface properties and in interactions with (salivary) agglutinin, an essential component of the innate immune system, most likely through deacetylation of an as-yet-unidentified polysaccharide. SmPgdA shows significant homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae (SpPgdA) and Listeria monocytogenes (LmPgdA), both of which are involved in the bacterial defense mechanism against human mucosal lysozyme. The Bacillus subtilis genome contains six polysaccharide deacetylase gene homologs: pdaA, pdaB (previously known as ybaN), yheN, yjeA, yxkH and ylxY. The biological function of BsYheN is still unknown. This family also includes many uncharacterized polysaccharide deacetylases mainly found in bacteria.	2.97225e-82
NZ_CP016588.1\|WP_000800677.1\|2852575_2852965_+\|VOC-family-protein	gnl\|CDD\|366361	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	2.94422e-13
NZ_CP016588.1\|WP_001100934.1\|2840279_2841440_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226925	COG4552, Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only].	5.32289e-70
NZ_CP016588.1\|WP_000643682.1\|2854115_2854817_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	1.22449e-08
NZ_CP016588.1\|WP_000709536.1\|2828494_2829025_+\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	6.16243e-64

>NZ_CP016588.1|WP_001107303.1|2841708_2842275_+|TetR/AcrR-family-transcriptional-regulator
MAKNKQEDIFDAAMQLFAERGYDGTTIPMIAEKAKVGAGTIYRYFENKEALVNSLFSKSMLQLSEIIKTDFPVEANIREQFSHTYNRLFEFARNNVDAFLFTNSHCDSYFLDEQSKKIFDDFIGFFMNIIEDGIAKGFLRPLPPVALIIIVYQPLEKLTKVIATGQLEYSKELVKELEESSWNAIRII
>NZ_CP016588.1|WP_001100934.1|2840279_2841440_+|GNAT-family-N-acetyltransferase
MNVIQLKEDQFREALRLSEYAFQYKVDEERLQQQLTKMKESHEIYGIMEGEDLAAKLHLIPFHIYIGKEKFKMGGVAGVATYPEYRRSGYVKELLQHSLQTMKKDGFTVSMLHPFAVSFYRKYGWELCANLLKCHISKSDLVMKKQVNGTVKRFNKENHPEEVEKLYEAFAERFSCMLVREKNWWLQAVYDDLTLAIYYDENKKAAGYMLYKIENYKMTVEEFVPLHNEARNGLWNFICQHDSMIKEIEMTVSESEPLLYSLQEPRVKTEIKPYFMGRIVDVEQFLKQYELNWSNVQQEVILNITDAFAPWNNITVRLANHEITIIKEKTIDKGIKLDINELSTIMFGYKRPLQLNELELISGSEEEIQAFEKIVPVREAFIYDFF
>NZ_CP016588.1|WP_000664634.1|2838864_2840154_+|3-phosphoshikimate-1-carboxyvinyltransferase
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGSIAEGKTTIKGFLPGADCLSTISCFKEMGVEITQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDESIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYISPVASAQVKSAILLAGLRAEGVTVVTEPHISRDHTERMLEAFGVKVTREGKTVKLSGGQKLTATDIQVPGDVSSAAFFLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVDLINEEASEPAANITIETSSLKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCLAEGKTIIEDAEAVGVSYPTFFDELQKLAK
>NZ_CP016588.1|WP_001228131.1|2837746_2838847_+|prephenate-dehydrogenase
MRKKVVLIGTGLIGGSLALAIKKEHDVTITGYDIFKEQVERAKELHVVDEIGVDLQRACEEAHLIVFASPVEETKKLLHKLASFRLREDVIVTDVGSTKGSIMNEAEALFSKDVSFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMNHVPNKQVEDLKVWLKGTGSHFLVLNTEEHDYVTGIVSHFPHLIAAGLVKQVEKHAGDNPLIHQLAAGGFKDITRIASSSPKMWSDIVKQNREHLMVLLKEWISEMEDLYKTVSTGDAGEIQNYFADAKEYRDSLPVRKRGAIPAYHDLYVDVLDKVGALAHITSILAREEISITNLQILEAREGLLGVLRISFQREEDRMKAKLALGEEEYQTYETI
>NZ_CP016588.1|WP_001197238.1|2836653_2837754_+|histidinol-phosphate-transaminase
MQVKDQLSSLQPYKPGKSPEQMKEVYGDHLFVKLASNENPFGCSPRVLEELQNSWLEHALYPDGGATTLRQTIADKLHVQMEQVLCGSGLDEIIQMISRAVLRAGDNIVTAGATFPQYRHHAIIEGCEVKEIPLNKGVYDLDEISSAVNNNTKIVWICNPNNPTGTYVNEQKLTQFIEDISENTLIVIDEAYYEYVTAKDFPETLPLLEKHKNILVLRTFSKAYGLASFRVGYAIGQEELIEKLNVVRLPFNVSSLAQKAATIAFGDDEFIKEIVHMNTEGLQQYESFCKENGIPFYSSQTNFIFLPVDNAGEIYEACAHAGFIIRPFPNGVRITVGTREQNEGVISVLKQHFENKKNKSRDEANA
>NZ_CP016588.1|WP_001269429.1|2835462_2836635_+|chorismate-synthase
MRYITAGESHGPQLTVILEGVPAGLTLTAEHINKELLRRQKGHGRGRRMQIETDTVEIVSGVRHGMTLGSPITLIVKNDDFKHWTKVMGAEPISEKESKDMKRTITKPRPGHADLNGAIKYGHRDIRNVLERSSARETTVRVAAGAVAKQILSELGVGIAGHVLEIGGVKAKHISNLSIEEIQTITENSPVRCLDKEVEQEMMNAIDNAKSSGDSIGGIVEVIAEGMPIGVGSYVHYDRKLDAKLAGAIMSINAFKGAEIGVGFEAARQPGSKVHDEILWDEKKGYTRKTNNAGGLEGGMTTGMPIIVRGVMKPIPTLYKPLASVDIDTKEAFQASIERSDSCAVPAAGVVAESVVAWELADALVEQFGKDRMELLKQNIMQHNNYAKEF
>NZ_CP016588.1|WP_001273575.1|2834103_2835180_+|3-deoxy-7-phosphoheptulonate-synthase
MANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAEHNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGTQTFIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDEFINAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVIVDVTHSTGRRDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMDELKGFKNKLS
>NZ_CP016588.1|WP_065703850.1|2829793_2833276_+|DUF4020-domain-containing-protein
MWITSEVEIPDELIDHLEQGKLVLFVGAGVSMKGKSNLPNFDDLVDEIAKTLYVEKREITEPHDYYLGKIAKTKDVHQVARDLVHIEKSKPNPLHYAIPRLFPLDTDIRIVTTNFDQHFTTAIKEINRDINVYYAPALPTGRAFKGLAYIHGNVEQEKEALILTDGDFGRAYLTEGWARRFLVDLFSNYTVLFIGYSHNDPVMKYLATGLPPSTRRFAFVAQGENTYHWEHLGIRPIVYPNKVNNHQPLVKAVKRWAELMGDNYITKRMRIRDIVTVPPSVEQEQLSYIKQSIKKIETVRYFVEFAHDYEWVEWLEAEGKLQNLFMLTPNYNEVDELLAEWLVEQFLFSHQKELFQLIYKNYSKISPLLWRTICNYLNETKSKMDPLLFARWTLLLLETAEKDSSSIEKISKLLQKCSFPEHKEIALLLLTFILDGKLKLKRVRKWGNDTQESIELEESSRLPVSTFSHVEQIWNEKMRPYIAYYAVPIMMIGLEKLRMLSLRQTALKKRNKENVEKEFHQNDLAFLIRIVKECLTYLCENNEKKADYYITEMIEANSVLQKRIAIDAMNKNIFVRVDDKMKWLLHEGLLLDFTYKHEVFQLLKRHYAYCLEKTKEEVTRTVIKHLTEERVFDAYLVLDLLFKCDSNSPSTANGYELMKQKHPHFHSERYSVQKKEDTAESITCNVTADGLLQLKDVEIMKQVQQFSQDGVFEQRHFLEMLSKACKLNTEWSISFAYQLVGVQEISNEVWFVCIREWRNNRGLTNEQIQKIIPLLQKFVRNTAFHWLISSFLYEISNRLEELEENSIRVVKRFAFSVFPQVMKSDTDFKLGKQDFYNESIQHPVGKMTAVLLKLLSYDHLYDRNVYEYLFLFEEQVRVNSERTNFMFARLIADITFLYHIEKQWCRKYLLPYLDLKKQNEITEYAWAGLCYTQINLPLFTEMKRFIKYAIEHLEVLHPHTREAFLKWLSFVFIKCVLYWEQKTNWLYPLLILENEENKIKFMQFLCYYVKTLSVKEQQKFWTAWLSVFLRERPKMGEITAREYVMLLRIILYMDEILEKGLCIMSRAFSSVHGKCTGEEMKRLLIEMLHKKESMKAHKEMFANVFFILLQTCHEAVLFEKEIIQIKELLVQYEVEEYVLHLLENEIIRIGIVMGDLQKEL
>NZ_CP016588.1|WP_000997702.1|2829174_2829612_-|YndM-family-protein
MNDFTVVLIKFISCIIAFSIGLALFFPATFVQIISFSLFVTIVSYMFVDKIILNRIGNTGAIMSDFLLTYLSVWIFGNILLDNYMQIAWGSILSAIVFTLSEVIVHRFSNSHTRHNNDNIRINRRFAYGTEFAEEQNILDKDKKK
>NZ_CP016588.1|WP_000709536.1|2828494_2829025_+|cysteine-hydrolase
MKKALIVIDVQAGMYTAGMPVHNGGKFLQTLQELIRECRSNDIPVIYIQHNGPKDHPLEKGTDGWRIHAAIAPQEGDHIVEKTTPDSFHNTNLSEVLQEKGIEHVILSGMQTEYCVDTTTRRACSEGYKVTLVSDAHSTFNTEVLRAEDIVKHHNAVLGAFADVVAVKDLKVAASK
>NZ_CP016588.1|WP_000040300.1|2842486_2845603_+|MMPL-family-transporter
MSKLKSWRSLSFLLWIVITITMVVTMPNMDQLVKEKGKITIPNTKQSSIADKMMKEMDKEGVEKYEIIAVFNSGNKAALTDEQKKEITKTINALQNEKEQLGIKEVVSHLDNKDLEKQLVSKDNTTILTQISIDKKHGEISKVSNNLHEKVQTKGVKTYLTGSDLIAGDFLKSSQEGVKKTEVISIIFILVVLILVFRSPVVPIVSLLTVGISYLVSMGIIAQLVDQFNFPFSNFTQVFVVVVLFGVGTDYNILLYTRFKEELSKQENAFLATKETFKSAGKTVLYSGIAVLIGFASLALASFKLYQSTSAVAIGVLVLLLVLTTLNPFFMVLLGKGMFYPVKTFKGHEDSRLWGFFAKNSVARPFVALIIVFVISIPFVLKYSNTLNYNDLFEVDNKYESKMGINVIEDHFPPGFSSPSTLVIQSDKKLDEGTSLQILDELTDKISKVKGVSEVYAPTRPTGEKIKELYLNKQAGELNTGLGDADGGIKEINDGLTDAKNKMGSNDSNSLANVQKLIDGTNEAKNGVSALGTALHQLSNGINDGAQGAQQIESGLASVNENINVLSNATSQLHAGYAQLEKGLNSYDQFFGSIFQAIDGAKKGYEQIEMLMTNFVQTKPELANDPNIQQTIGIAKEAQKKLSVLSNELNQLATQHKTAMSSFKEANQSLLKVDNGLKEMSNGVNKLQKGAADLKNGLNEGSSGSKQIANKSVELQSGLTKINDGQGQLLTGLKDLQEKMGQLQSGLSKSTEGLGKVSNGLHDAQKYLGELNESKSSEKFYIPKEVLEGEDFQKALNTYMSQDRKIAKMTIILDVNPYSKEAMPIIQEINKTIDGTVKGTELHDAKTAIGGTTARNVDLKEVTGQDFLRTATIMLIGIAIVLIVITRSLLNTIFIIGSLLLAYFASLGISEQISAHVLHVDSLSWNVPFFSFIMIVALGVDYSIFVMMRYNEIEGDSVTKIVTASRHIGGVVLSAALILGGTFAALIPSGVLTLIQVASVVGVALLLLALIVMPILLPALIGLTSKMKSYKEKIINTK
>NZ_CP016588.1|WP_000633864.1|2845915_2847541_+|ATP-binding-cassette-domain-containing-protein
MITVSNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIEPSTGDIHITPGERLAVLKQNHFEYEEFPVLETVIMGHTQLYKVMQEKNAIYMKEDFSDEDGMRAAELEGEFAELNGWEAESEAAILLKGLGIGEDLHDKKLSELTGAEKVKVLLAQALFGQPDILLLDEPTNHLDLKAIQWLENFLMNFENTVIVVSHDRHFLNKVCTHMADLDFGKIQLYVGNYDFWYESSQLALKLTQDANKKKEEKVKELQNFIARFSSNASKAKQATSRKKLLDKITLDDIRPSSRRYPFVGFTPEREVGNDLLTVEGLSKTIDGEKVLDNVYFTLNKGDKVAFIGRNDIAMTTLFKILMGEMEPDSGSFKWGVTTSQSYFPRDNSKYFENSDYNLVEWLRQFSPQDESESFLRGFLGRMLFSGEEVKKNVSVLSGGEKVRCMLSKMMLSGANVITLDDPTNHLDLESITALNNGLIAFKGTILFTSHDHQFVQTIANRIIEVTPNGVIDKEATYDEFLENEELQKQVDAMYKGQ
>NZ_CP016588.1|WP_000808774.1|2848068_2850042_+|LTA-synthase-family-protein
MKQFLLKSKSVLSNHFGFFLFAVILLWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAVLFLGLALFAKGKRSYIWLIIINLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGSILALLHLYDPLYFLDTIILIVLVATKFANPKPIRVAKHKLSLVFVVGILLFSVNLGLAESDRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYASPNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQGSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNEKDVVNYGLKDKPFFNESIPLLQTLKQPFYTKFITLSNHFPYPIDKAEATIEPATTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHYGISDNHNAAMSKVMGKEMNSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLLGTDTKNYVQFGSDLLSPDHKQVVAFRNGNYVSPTVTALNGKYYDTTTGKPVEFTDEIKKNEQMVQNSLKYSDQVVNGDLLRFYTPEGFTPVDRSKYNYNNRDKNKTKVKTTPEGEAK
>NZ_CP016588.1|WP_000346944.1|2850098_2850773_-|TerC-family-protein
MDFLSPEYLSALLAIIVIDLVLAGDNAIVIGLAARRLPKDQQKKVIIWGTIGAIAIRALATLVVVWLLKIPGLLLIGGVLLIWIAYKLIAEGKNHDIKAEEGFWSAIKTIIIADALMGIDNVLAVAGAAHGNFSLVIIGLLVSIPVVVWGSTLILKWVDRFPVIITIGAAVLAYTAAKMIVDEKWFAGFFESNPFVKWAFIIIIIVGVVFFGKAKQKATAGFVS
>NZ_CP016588.1|WP_000551443.1|2851165_2851993_-|polysaccharide-deacetylase
MHNGIRMTTLVKRAMLVCAGVLFTYEAAFGSVHTALASTEDEAKSVQLVSEIQTSLAPKEAPKHYNGQVRKVAYLTFDDGPGKYTAELLDMLKKENAKATFFLIGSNVKAFPDLVKREDAEGHYVGMHSMTHNYKKLYTEGHYVDEMKEDQGLIAGVLGKSPVLTRPAYGSMPGLNEALRNKVVDNGLKVWDWTIDSLDWKYNKMQVDAASAKIVENVLAHSTNPTEVILMHDIHPQSVKAVPGIIKGLKEKGYELEAYNENEHFPLNFWHDNRM
>NZ_CP016588.1|WP_001067270.1|2852285_2852444_+|hypothetical-protein
MNNYICTTCGVQYPENEEAPSHCKICNEERPYVNPIGQSWITLETMQNSNLY
>NZ_CP016588.1|WP_000800677.1|2852575_2852965_+|VOC-family-protein
MKNWVQFRIARPTDKLEEVISFYETGLGLKRIGEFHNHEGYDGVMFGLPDEEYHLEFTSHVNGSPCPAPTKDNLLVFYMPNKDEIENIVNRLSNMGYHEVEPENPYWIEKGTTIEDPDGWRIVLMNASE
>NZ_CP016588.1|WP_000923455.1|2853415_2854099_+|DNA-alkylation-repair-protein
MLLEEVMQQLEEYGTEQNRKTYKNHGAKEPLFGVSFANLKLLKKKIKKDHDLAVGLWETKNMDAMTLATYILDPKKITTEQLNSWIQDVDYYCLMDVLMTSICTSPIAIERMEEWTKSNDEWIGRAGWSLLANIAIKNKTLHDDFFSPYLEEIKENIHNEKNRKKEAMNSALIAIGIRNEDLERQAIEIAREIGKVEVDHGATSCKTPDAESYIKKARERAEKKKVK
>NZ_CP016588.1|WP_000643682.1|2854115_2854817_+|nucleotidyltransferase-domain-containing-protein
MKAIDAAQNIITLQFSNCDVALLGGSVARGEATKTSDLDIVIVDQSLTSCYRESFYSNGWPVEVFVHNFETYKTFFKMDCDRGRPSLPQLVSEGIALKGEKEIVEKLKKEANDLLHKGPAKWTEETIKQKRYFITDTLDDFIGATKREEELFIANLLADLVHEYVLRVNGKWLGSSKWFIRVLRRYDEQYANKFVAAFDHFYKTGEKNELIHFIEKTLEQYGGRVFEGFSIGK
>NZ_CP016588.1|WP_001102496.1|2854832_2855390_+|GNAT-family-N-acetyltransferase
MNVPYVQLRELTLDDVEDRYQWSLDRDVTKHLVVPDQYPPFTRGDTRNWIEACISRKNGYEQRAIVTEAGIHIGWVDLKNFDKTNKNAELGIAIGNKDYWGKGFGMAALNSMLQIGFSQFELEKIWLRVDEDNTKAKKSYESAGFVCEGLMRNDRLRQGKFIHRNRYSILKEEYESKKVAYKNIM

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016588_1	1.2\|2842390\|37\|NZ_CP016588\|PILER-CR	2842390-2842426	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	275548-275584	11	0.703

1. spacer 1.2|2842390|37|NZ_CP016588|PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 11, identity: 0.703

gaaagactagtttaatagaatttacaaaataatgtaa	CRISPR spacer
gatgtttcttattaatataatttacaaaataatctaa	Protospacer
** .  ..   ****** *************** ***

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

57268 : 65216

Bacillus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000719210.1\|57268_58774_-	aminopeptidase AmpS	W8CYF6	Bacillus_phage	7.8e-31	30.0
WP_000929887.1\|58757_59459_-	response regulator transcription factor	W8CYM9	Bacillus_phage	7.3e-40	36.4
WP_000833096.1\|59602_60928_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	4.1e-44	29.4
WP_000743906.1\|61313_62852_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	8.8e-22	31.7
WP_001029993.1\|63258_64893_-	chaperonin GroEL	A0A219YK78	uncultured_virus	1.5e-157	58.0
WP_000917311.1\|64931_65216_-	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8

DBSCAN-SWA_2

1858677 : 1969582

108

Bacillus_phage(52.17%)

tail,transposase,terminase,head,integrase,coat,protease,portal,tRNA,holin

attL 1858859:1858876|attR 1930360:1930377

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000213002.1\|1858677_1859982_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
1858859:1858876	attL	NA	NA	NA	NA
WP_001101241.1\|1860047_1860947_+	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	3.1e-35	31.8
WP_000526272.1\|1860989_1861532_+\|protease	ATP-dependent protease proteolytic subunit HslV	NA	NA	NA	NA
WP_000550087.1\|1861554_1862946_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A173GFL6	Erwinia_phage	3.2e-47	30.0
WP_000421290.1\|1863023_1863803_+	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_000111485.1\|1864151_1864853_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_001018578.1\|1864956_1865844_+	elongation factor Ts	NA	NA	NA	NA
WP_000042668.1\|1865910_1866633_+	UMP kinase	NA	NA	NA	NA
WP_000531501.1\|1866635_1867193_+	ribosome recycling factor	NA	NA	NA	NA
WP_000971296.1\|1867278_1868055_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	9.0e-23	42.5
WP_000813594.1\|1868072_1868864_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_000790372.1\|1868887_1870030_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_001090245.1\|1870047_1871304_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_065703272.1\|1871413_1873114_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_065703274.1\|1873238_1877540_+	PolC-type DNA polymerase III	A0A0A8WJ41	Clostridium_phage	4.1e-24	39.6
WP_000359096.1\|1877876_1878347_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_000102604.1\|1878364_1879471_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_000071127.1\|1879482_1879755_+	YlxR family protein	NA	NA	NA	NA
WP_001286524.1\|1879755_1880067_+	YlxQ family RNA-binding protein	NA	NA	NA	NA
WP_000036343.1\|1880071_1882132_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	3.8e-20	25.9
WP_000582367.1\|1882128_1882410_+	DUF503 family protein	NA	NA	NA	NA
WP_000776437.1\|1882425_1882782_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_065703281.1\|1882868_1883792_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_000766702.1\|1883835_1884807_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_001229392.1\|1884907_1885177_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_000076737.1\|1885337_1887476_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_000868232.1\|1887630_1888530_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_000592989.1\|1888616_1889858_+	insulinase family protein	G3MBJ8	Bacillus_virus	4.4e-56	34.5
WP_001239756.1\|1889992_1890244_+	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_000954735.1\|1890414_1891317_+	dipicolinic acid synthetase subunit A	NA	NA	NA	NA
WP_065703284.1\|1891771_1893319_-	serine recombinase	I3VYZ3	Thermoanaerobacterium_phage	9.5e-141	52.6
WP_065703287.1\|1893461_1894211_-	hypothetical protein	NA	NA	NA	NA
WP_065703289.1\|1894508_1895042_-	hypothetical protein	NA	NA	NA	NA
WP_048558726.1\|1895082_1895517_-	ImmA/IrrE family metallo-endopeptidase	D2XR38	Bacillus_phage	1.3e-60	77.8
WP_065703292.1\|1895529_1895967_-	helix-turn-helix transcriptional regulator	D2XR39	Bacillus_phage	5.4e-33	59.9
WP_065703294.1\|1896139_1896331_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_065703296.1\|1896363_1896612_+	hypothetical protein	NA	NA	NA	NA
WP_000537273.1\|1896702_1897290_+	hypothetical protein	D2XR41	Bacillus_phage	4.9e-74	69.2
WP_000215315.1\|1897303_1897525_+	hypothetical protein	NA	NA	NA	NA
WP_065703299.1\|1897705_1897990_+	hypothetical protein	D2XR42	Bacillus_phage	9.5e-23	54.3
WP_065703302.1\|1898269_1899220_+	DnaD domain protein	D2XR43	Bacillus_phage	4.0e-73	59.7
WP_065703304.1\|1899216_1900539_+	replicative DNA helicase	D2XR44	Bacillus_phage	2.1e-237	95.5
WP_065703306.1\|1900541_1900730_+	hypothetical protein	D2XR45	Bacillus_phage	2.2e-15	85.5
WP_065703308.1\|1900704_1901067_+	cell division protein SepF	D2XR47	Bacillus_phage	1.4e-55	90.0
WP_065703314.1\|1901141_1901333_+	DUF3954 domain-containing protein	D2XR48	Bacillus_phage	4.6e-21	83.3
WP_033693376.1\|1901447_1902242_+	hypothetical protein	NA	NA	NA	NA
WP_065703316.1\|1902267_1903452_+	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	1.4e-35	28.6
WP_065703318.1\|1903681_1904737_+	hypothetical protein	NA	NA	NA	NA
WP_065703320.1\|1904738_1906037_+	hypothetical protein	NA	NA	NA	NA
WP_065703322.1\|1906239_1906725_+	ArpU family transcriptional regulator	A0A1B0T6C9	Bacillus_phage	8.0e-62	72.3
WP_065703324.1\|1906721_1907264_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	4.9e-92	95.0
WP_098283659.1\|1907445_1907976_+	hypothetical protein	NA	NA	NA	NA
WP_065703326.1\|1908403_1908664_+	hypothetical protein	NA	NA	NA	NA
WP_065703328.1\|1908741_1908987_+	hypothetical protein	NA	NA	NA	NA
WP_065703330.1\|1908988_1909201_+	hypothetical protein	A0A1B1P7X2	Bacillus_phage	4.6e-14	67.9
WP_065703332.1\|1909187_1909523_+	HNH endonuclease	D2XR61	Bacillus_phage	1.8e-52	90.1
WP_065703334.1\|1909674_1910031_+	hypothetical protein	A0A2H4JBV9	uncultured_Caudovirales_phage	1.0e-58	99.2
WP_065703336.1\|1910027_1911683_+\|terminase	terminase large subunit	A0A2H4JI41	uncultured_Caudovirales_phage	6.1e-311	95.5
WP_065704997.1\|1911748_1912855_+\|portal	phage portal protein	A0A2H4JAJ1	uncultured_Caudovirales_phage	2.4e-186	90.1
WP_065703339.1\|1912838_1913615_+\|protease	Clp protease ClpP	A0A0A7RWX3	Clostridium_phage	3.3e-57	57.7
WP_065703341.1\|1913635_1914799_+	hypothetical protein	A0A2H4JH29	uncultured_Caudovirales_phage	1.5e-210	96.1
WP_065703342.1\|1914811_1915108_+	hypothetical protein	D2XR19	Bacillus_phage	3.3e-42	87.5
WP_065703344.1\|1915109_1915460_+\|head	phage head closure protein	D2XR20	Bacillus_phage	2.7e-51	85.2
WP_000997556.1\|1915461_1915806_+	HK97 gp10 family phage protein	A0A2H4JAH8	uncultured_Caudovirales_phage	8.8e-47	82.3
WP_000176452.1\|1915802_1916138_+	hypothetical protein	D2XR22	Bacillus_phage	7.5e-51	89.9
WP_065703346.1\|1916138_1916726_+\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	7.4e-86	81.0
WP_000415912.1\|1916730_1917093_+	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	2.4e-42	70.8
WP_065703348.1\|1917325_1920952_+	DUF2207 domain-containing protein	A0A2H4JAI2	uncultured_Caudovirales_phage	1.8e-182	85.5
WP_065703350.1\|1920993_1922463_+\|tail	phage tail protein	A0A0S2MV63	Bacillus_phage	5.3e-234	80.0
WP_065703352.1\|1922459_1928024_+	hypothetical protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	57.3
WP_065703354.1\|1928039_1928414_+	hypothetical protein	A0A0S2MVE0	Bacillus_phage	2.7e-65	97.6
WP_065703356.1\|1928531_1929917_+	PQQ-like beta-propeller repeat protein	NA	NA	NA	NA
WP_065703361.1\|1930004_1930430_+\|holin	phage holin family protein	A0A1B1P787	Bacillus_phage	1.4e-70	96.5
1930360:1930377	attR	NA	NA	NA	NA
WP_065703364.1\|1930429_1931239_+	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	1.3e-152	91.8
WP_065703366.1\|1931566_1932064_-	hypothetical protein	A0A1B2APY6	Phage_Wrath	1.2e-68	79.4
WP_154214719.1\|1932221_1932455_+	dipicolinate synthase	NA	NA	NA	NA
WP_000414846.1\|1932605_1933652_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000692451.1\|1933675_1934908_+	aspartate kinase	NA	NA	NA	NA
WP_000564763.1\|1934919_1935798_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_000823098.1\|1936534_1938205_+	ribonuclease J	NA	NA	NA	NA
WP_000139806.1\|1938306_1939056_+	translocation-enhancing protein TepA	NA	NA	NA	NA
WP_000605020.1\|1939052_1939256_+	ribonuclease	NA	NA	NA	NA
WP_001118776.1\|1939468_1941850_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.0e-89	51.4
WP_155759224.1\|1941922_1943291_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.2e-93	65.3
WP_000114182.1\|1943845_1944571_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_065703368.1\|1944663_1945749_+	BMP family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000456909.1\|1945866_1947399_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.8e-12	26.6
WP_001085254.1\|1947391_1948450_+	ABC transporter permease	NA	NA	NA	NA
WP_000008857.1\|1948450_1949410_+	ABC transporter permease	NA	NA	NA	NA
WP_000772405.1\|1949619_1950894_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.2e-56	30.1
WP_065703370.1\|1950894_1952181_+	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	1.7e-10	28.9
WP_000759606.1\|1952281_1952995_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_000114450.1\|1953070_1953319_+	DUF3243 domain-containing protein	NA	NA	NA	NA
WP_000574107.1\|1953457_1954243_+	DUF3388 domain-containing protein	NA	NA	NA	NA
WP_065703372.1\|1954264_1955221_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_065703374.1\|1955285_1955864_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_000990688.1\|1955884_1957123_+	competence/damage-inducible protein CinA	NA	NA	NA	NA
WP_065703376.1\|1957972_1958596_+	topoisomerase I	NA	NA	NA	NA
WP_001115373.1\|1958861_1959287_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	2.7e-45	68.9
WP_000099770.1\|1959768_1961334_+	ribonuclease Y	NA	NA	NA	NA
WP_065703378.1\|1961496_1962291_+	TIGR00282 family metallophosphoesterase	NA	NA	NA	NA
WP_000404341.1\|1962440_1962701_+	stage V sporulation protein SpoVS	J9PTX7	Bacillus_phage	8.4e-10	43.8
WP_065703380.1\|1962759_1963683_+	membrane dipeptidase	NA	NA	NA	NA
WP_000625417.1\|1963907_1965665_+	2-oxoacid:acceptor oxidoreductase subunit alpha	NA	NA	NA	NA
WP_000190155.1\|1965651_1966518_+	2-oxoacid:ferredoxin oxidoreductase subunit beta	NA	NA	NA	NA
WP_065703382.1\|1966948_1968478_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_000870461.1\|1968481_1968913_+	hypothetical protein	NA	NA	NA	NA
WP_001288799.1\|1969039_1969582_+\|coat	outer spore coat protein CotE	NA	NA	NA	NA

DBSCAN-SWA_3

2042144 : 2051470

uncultured_Caudovirales_phage(40.0%)

bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033683142.1\|2042144_2042804_-	helix-turn-helix domain-containing protein	A0A2H4J441	uncultured_Caudovirales_phage	8.7e-35	41.0
WP_000283431.1\|2043008_2043221_+	hypothetical protein	A6M975	Geobacillus_virus	1.6e-11	63.0
WP_065703428.1\|2043423_2044182_+	antirepressor	A0A2H4JBC7	uncultured_Caudovirales_phage	3.0e-95	69.0
WP_001189064.1\|2044193_2044388_+	hypothetical protein	A0A2H4J4V8	uncultured_Caudovirales_phage	5.9e-16	71.0
WP_065703430.1\|2044540_2045413_+	DnaD domain protein	A0A2H4J394	uncultured_Caudovirales_phage	6.2e-97	60.5
WP_000464424.1\|2045821_2046208_+	DUF1492 domain-containing protein	A0A288WG73	Bacillus_phage	2.2e-46	70.6
WP_065705001.1\|2046446_2047433_+	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.4e-33	42.8
WP_065703432.1\|2047588_2048431_+	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	9.7e-31	45.5
WP_000392443.1\|2048492_2048723_+\|bacteriocin	bacteriocin biosynthesis protein	A0A1B1P7Q9	Bacillus_phage	1.7e-25	77.6
WP_001102627.1\|2049094_2049418_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_065703434.1\|2049410_2049953_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000976240.1\|2049953_2050757_+	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_000413738.1\|2050849_2051470_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	8.2e-19	62.2

DBSCAN-SWA_4

3097416 : 3102653

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001163828.1\|3097416_3098091_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.8e-28	30.7
WP_000411453.1\|3098103_3098634_-	hypothetical protein	NA	NA	NA	NA
WP_065703994.1\|3098751_3099261_-	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	4.1e-16	35.4
WP_065703996.1\|3099388_3100270_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_002061469.1\|3100407_3100608_-	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	1.0e-15	90.9
WP_002061468.1\|3100672_3100885_-	hypothetical protein	NA	NA	NA	NA
WP_000097509.1\|3100904_3101705_-	C1 family peptidase	A0A2K9L1Z4	Tupanvirus	1.0e-37	37.2
WP_000369348.1\|3102069_3102201_-	DUF3983 domain-containing protein	A0A1B1P7V8	Bacillus_phage	2.9e-11	79.1
WP_001139345.1\|3102437_3102653_+	spore germination protein	A0A2H4J3A3	uncultured_Caudovirales_phage	3.4e-25	83.8

DBSCAN-SWA_5

3137340 : 3163527

Bacillus_phage(48.0%)

head,terminase,integrase,protease,capsid,portal,tail

attL 3131606:3131621|attR 3167350:3167365

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3131606:3131621	attL	NA	NA	NA	NA
WP_025710284.1\|3137340_3138405_-	N-acetylmuramoyl-L-alanine amidase	A0A0A7AQV3	Bacillus_phage	9.9e-198	94.4
WP_000461725.1\|3138401_3138641_-	hypothetical protein	A0A0A7AR38	Bacillus_phage	1.0e-33	96.2
WP_025710285.1\|3138640_3138877_-	hypothetical protein	A0A2H4J382	uncultured_Caudovirales_phage	2.0e-18	98.7
WP_065704015.1\|3138970_3139345_-	hypothetical protein	A0A0S2MVE0	Bacillus_phage	1.8e-45	76.9
WP_065704017.1\|3139356_3143676_-	hypothetical protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	58.9
WP_065704018.1\|3143672_3145130_-\|tail	phage tail protein	A0A0A7AQV1	Bacillus_phage	3.4e-172	59.3
WP_065704020.1\|3145171_3148759_-	DUF2207 domain-containing protein	A0A2H4JAI2	uncultured_Caudovirales_phage	2.8e-196	90.3
WP_065704022.1\|3148989_3149352_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	5.4e-55	85.8
WP_065704024.1\|3149358_3149946_-\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	1.1e-86	82.1
WP_065704026.1\|3149946_3150285_-	hypothetical protein	A0A2H4JAG4	uncultured_Caudovirales_phage	8.6e-47	85.5
WP_065704028.1\|3150281_3150626_-	HK97 gp10 family phage protein	A0A2H4JAH8	uncultured_Caudovirales_phage	7.4e-46	81.4
WP_065704030.1\|3150627_3150981_-\|head	phage head closure protein	A0A2H4JGG7	uncultured_Caudovirales_phage	1.7e-58	96.6
WP_065704032.1\|3150982_3151276_-	hypothetical protein	D2XR19	Bacillus_phage	2.5e-42	87.6
WP_065704034.1\|3151288_3152452_-\|capsid	phage major capsid protein	A0A2H4JH29	uncultured_Caudovirales_phage	2.1e-185	84.8
WP_065704036.1\|3152471_3153248_-\|protease	Clp protease ClpP	R9TLM7	Paenibacillus_phage	3.3e-57	52.8
WP_065705031.1\|3153231_3154338_-\|portal	phage portal protein	A0A2H4JAJ1	uncultured_Caudovirales_phage	1.4e-186	90.4
WP_065704038.1\|3154402_3156058_-\|terminase	terminase large subunit	A0A2H4JI41	uncultured_Caudovirales_phage	2.5e-309	94.9
WP_000763336.1\|3156054_3156411_-	hypothetical protein	A0A2H4JBV9	uncultured_Caudovirales_phage	3.6e-59	100.0
WP_001258476.1\|3156561_3156903_-	HNH endonuclease	D2XR61	Bacillus_phage	3.6e-53	92.7
WP_065704040.1\|3156883_3157297_-	hypothetical protein	Q2I8B8	Bacillus_phage	5.3e-30	53.3
WP_065704045.1\|3158148_3158424_-	hypothetical protein	A0A1B1P857	Bacillus_phage	3.4e-33	72.5
WP_000930969.1\|3158795_3159014_-	hypothetical protein	H0USV5	Bacillus_phage	5.2e-21	66.2
WP_016081850.1\|3159356_3160526_-	serine hydrolase	A0A1D8EXR7	Mycobacterium_phage	6.1e-23	28.6
WP_065704047.1\|3161337_3162288_-	nucleoside hydrolase	NA	NA	NA	NA
WP_001012135.1\|3162502_3163045_-\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	7.3e-88	91.1
WP_016081851.1\|3163044_3163527_-	ArpU family phage transcriptional regulator	H0USV3	Bacillus_phage	2.5e-71	82.5
3167350:3167365	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3169783 : 3173755

Bacillus_phage(77.78%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065704057.1\|3169783_3170293_-	dUTPase	A0A1L2JY27	Aeribacillus_phage	6.7e-27	45.4
WP_065704059.1\|3170312_3170564_-	hypothetical protein	A0A1B1P7W1	Bacillus_phage	1.3e-15	48.7
WP_000717825.1\|3170589_3170757_-	DUF3954 domain-containing protein	A0A1B0T6B8	Bacillus_phage	1.8e-13	62.3
WP_065704060.1\|3170775_3171135_-	cell division protein SepF	A0A1B1P7A1	Bacillus_phage	2.4e-31	52.5
WP_065704062.1\|3171127_3171406_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	2.7e-14	66.1
WP_065704065.1\|3171409_3172465_-	DnaD domain protein	W8CYG5	Bacillus_phage	1.6e-59	44.2
WP_000522028.1\|3172686_3172953_-	helix-turn-helix domain-containing protein	A0A0U3ULL9	Bacillus_phage	6.4e-37	92.9
WP_065704067.1\|3173009_3173201_-	helix-turn-helix transcriptional regulator	A0A0U3SLC2	Bacillus_phage	8.3e-23	85.2
WP_065704069.1\|3173401_3173755_+	helix-turn-helix transcriptional regulator	A0A0U3SD25	Bacillus_phage	3.4e-46	82.8

DBSCAN-SWA_7

3795411 : 3803507

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001258541.1\|3795411_3796284_-	aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	1.6e-65	44.8
WP_065704333.1\|3796574_3797294_-	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_065704335.1\|3797521_3798595_-	sensor histidine kinase	W8CYF6	Bacillus_phage	5.1e-186	97.2
WP_065704337.1\|3798591_3799269_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.3e-122	98.7
WP_065704339.1\|3799355_3801116_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.8e-273	98.2
WP_001194306.1\|3801356_3802121_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000755513.1\|3802220_3803507_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.4e-11	31.5

DBSCAN-SWA_8

5324950 : 5333326

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000088589.1\|5324950_5325538_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.1e-28	37.4
WP_001262439.1\|5325534_5326575_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.9
WP_000879025.1\|5326680_5328096_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-55	35.4
WP_000055562.1\|5328080_5330300_-	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.6e-163	41.2
WP_000666787.1\|5330283_5330967_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000278823.1\|5330963_5331218_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_001170544.1\|5331210_5331930_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000625682.1\|5332018_5333326_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP016589

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7156 : 50027

Bacillus_phage(55.56%)

tail,protease,integrase,transposase

attL 7108:7122|attR 20200:20214

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
7108:7122	attL	NA	NA	NA	NA
WP_000358766.1\|7156_7729_+\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	5.4e-33	42.9
WP_065705087.1\|7915_8395_-	hypothetical protein	NA	NA	NA	NA
WP_065705090.1\|10078_10729_+	hypothetical protein	NA	NA	NA	NA
WP_065705092.1\|10772_11123_-	hypothetical protein	NA	NA	NA	NA
WP_065705094.1\|11354_11780_-	thioredoxin family protein	NA	NA	NA	NA
WP_001084323.1\|11776_12217_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_065705096.1\|12894_13377_+	thioredoxin family protein	NA	NA	NA	NA
WP_065705099.1\|13416_14562_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_065704714.1\|15161_16373_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.4e-70	41.4
WP_000169374.1\|17001_18309_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	8.6e-26	29.7
WP_001100112.1\|18482_18662_-	hypothetical protein	NA	NA	NA	NA
WP_065705100.1\|20126_20720_-	cupin domain-containing protein	NA	NA	NA	NA
20200:20214	attR	NA	NA	NA	NA
WP_065705104.1\|21879_22998_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	2.9e-171	80.6
WP_065705107.1\|23320_23632_-	hypothetical protein	NA	NA	NA	NA
WP_065705108.1\|23784_24195_-	hypothetical protein	NA	NA	NA	NA
WP_065705110.1\|24523_25024_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_065705114.1\|26065_26341_-	hypothetical protein	NA	NA	NA	NA
WP_098781304.1\|26388_26529_-	HTH domain-containing protein	NA	NA	NA	NA
WP_065705116.1\|26674_26941_-	hypothetical protein	NA	NA	NA	NA
WP_065705118.1\|27001_27490_-	hypothetical protein	A6XML4	Bacillus_virus	1.5e-15	53.8
WP_065705121.1\|27775_28321_-	hypothetical protein	A0A0H4TI24	Erysipelothrix_phage	1.5e-11	29.7
WP_065705123.1\|28634_30521_-\|tail	tail fiber domain-containing protein	D2XR28	Bacillus_phage	3.1e-109	41.3
WP_155759244.1\|30545_32177_-	hypothetical protein	A0A0M4RER0	Bacillus_phage	1.1e-59	48.1
WP_065705127.1\|32570_32771_+	hypothetical protein	NA	NA	NA	NA
WP_065705129.1\|33054_33738_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_065705131.1\|33949_34558_+	DUF998 domain-containing protein	NA	NA	NA	NA
WP_065705135.1\|35421_35805_-	hypothetical protein	NA	NA	NA	NA
WP_000757467.1\|35969_36545_-	hypothetical protein	NA	NA	NA	NA
WP_065705137.1\|36561_38766_-	peptidoglycan DD-metalloendopeptidase family protein	A7KUS1	Bacillus_phage	1.5e-14	37.5
WP_065705139.1\|38762_42764_-	hypothetical protein	NA	NA	NA	NA
WP_000765108.1\|42794_44891_-	DUF87 domain-containing protein	NA	NA	NA	NA
WP_000892003.1\|44893_45808_-	hypothetical protein	NA	NA	NA	NA
WP_001233532.1\|45808_46159_-	PrgI family protein	NA	NA	NA	NA
WP_000935868.1\|46225_46561_-	hypothetical protein	NA	NA	NA	NA
WP_065705141.1\|46961_47462_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_065705143.1\|48000_48519_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_065705145.1\|49127_50027_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA

DBSCAN-SWA_2

133858 : 175776

Bacillus_phage(65.22%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065705221.1\|133858_134338_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_065705223.1\|135568_137311_+	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_001167047.1\|137476_137692_+	alpha/beta-type small acid-soluble spore protein	A0A1P8CX76	Bacillus_phage	3.7e-19	68.7
WP_000733521.1\|137764_138181_-	hypothetical protein	NA	NA	NA	NA
WP_065705225.1\|139022_140117_-	tetratricopeptide repeat protein	A0A2H4J8G3	uncultured_Caudovirales_phage	1.8e-93	49.3
WP_065705227.1\|140963_142082_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	6.4e-171	80.4
WP_065705229.1\|142322_143585_+	hypothetical protein	M4HQ50	Bacillus_phage	2.0e-24	46.2
WP_065705231.1\|143647_144988_+	C40 family peptidase	A0A0A8WF62	Clostridium_phage	5.3e-15	39.8
WP_065705233.1\|145255_146626_+	M23 family metallopeptidase	D7RWE0	Brochothrix_phage	3.3e-20	42.6
WP_065705235.1\|147262_148012_+	AAA family ATPase	A0A2H4J4U1	uncultured_Caudovirales_phage	7.8e-32	38.3
WP_065705236.1\|148437_149361_+	HNH endonuclease	NA	NA	NA	NA
WP_065705238.1\|149435_149798_+	hypothetical protein	NA	NA	NA	NA
WP_065705240.1\|149866_150196_+	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_065705242.1\|150343_152026_+	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_155759246.1\|152441_152594_+	hypothetical protein	NA	NA	NA	NA
WP_085963828.1\|153442_154605_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.7e-33	42.6
WP_065705244.1\|154790_155279_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000854592.1\|155530_155758_+	hypothetical protein	NA	NA	NA	NA
WP_065705245.1\|155840_157235_+	glycosyltransferase	A0A0N9R395	Chrysochromulina_ericina_virus	6.6e-08	25.6
WP_065705247.1\|157337_157688_+	hypothetical protein	NA	NA	NA	NA
WP_065705249.1\|157769_159989_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	2.7e-48	28.8
WP_065705251.1\|159981_161289_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_065705253.1\|162109_162538_-	ImmA/IrrE family metallo-endopeptidase	Q9T201	Bacillus_phage	1.6e-34	55.1
WP_065705255.1\|162560_162989_-	helix-turn-helix transcriptional regulator	Q786F1	Bacillus_phage	1.2e-29	51.4
WP_065705257.1\|163125_163362_+	helix-turn-helix transcriptional regulator	W8CYU0	Bacillus_phage	2.8e-12	60.0
WP_065705258.1\|163588_164485_+	DnaD domain protein	A0A1C8E9B4	Bacillus_phage	7.8e-79	56.2
WP_065705261.1\|164588_164975_+	hypothetical protein	A0A288WG73	Bacillus_phage	1.5e-47	71.4
WP_065705263.1\|165212_166181_+	lysozyme family protein	A0A223LKM8	Bacillus_phage	4.1e-33	42.9
WP_065705265.1\|166322_167144_+	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	1.2e-28	43.8
WP_065705266.1\|167416_168301_+	N-acetylmuramoyl-L-alanine amidase family protein	A0A0S2MVR5	Bacillus_phage	5.5e-77	52.4
WP_000377824.1\|169015_169252_+	hypothetical protein	A0A288WG97	Bacillus_phage	3.9e-14	88.6
WP_000570185.1\|169251_169491_+	hypothetical protein	A0A0A7AR38	Bacillus_phage	2.7e-26	75.9
WP_065705268.1\|169487_170543_+	N-acetylmuramoyl-L-alanine amidase	A0A1B0T6C8	Bacillus_phage	2.9e-149	70.7
WP_065705270.1\|170860_171436_+	hypothetical protein	NA	NA	NA	NA
WP_065705272.1\|171957_172302_-	hypothetical protein	NA	NA	NA	NA
WP_000895161.1\|172370_172559_-	hypothetical protein	NA	NA	NA	NA
WP_065705274.1\|172644_172845_-	hypothetical protein	NA	NA	NA	NA
WP_065705276.1\|174253_175366_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A286QQB7	Streptococcus_phage	2.3e-80	45.2
WP_065705278.1\|175377_175776_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	8.0e-52	69.7

DBSCAN-SWA_3

297317 : 333896

Bacillus_phage(50.0%)

integrase,transposase

attL 290431:290468|attR 306012:306049

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
290431:290468	attL	NA	NA	NA	NA
WP_065705423.1\|297317_298430_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A286QQB7	Streptococcus_phage	2.3e-80	45.2
WP_000762752.1\|298441_298840_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.1e-51	68.9
WP_065705425.1\|299136_299568_+	hypothetical protein	NA	NA	NA	NA
WP_000624348.1\|299624_300437_+	hypothetical protein	NA	NA	NA	NA
WP_065705427.1\|300423_301254_+	hypothetical protein	NA	NA	NA	NA
WP_065705429.1\|301253_302075_+	hypothetical protein	NA	NA	NA	NA
WP_065705432.1\|302092_302758_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-32	37.8
WP_065705434.1\|302754_303306_+	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_065705437.1\|303361_303937_-\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	1.6e-29	41.8
WP_001057802.1\|303926_304268_-	YolD-like family protein	NA	NA	NA	NA
WP_155759250.1\|304264_305533_-	DNA repair protein	O64031	Bacillus_phage	9.0e-105	47.9
WP_065705440.1\|306218_307337_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	2.9e-171	80.4
306012:306049	attR	NA	NA	NA	NA
WP_000582597.1\|309004_309637_+	hypothetical protein	NA	NA	NA	NA
WP_000817896.1\|309633_310269_+	hypothetical protein	NA	NA	NA	NA
WP_000828218.1\|310565_310949_+	hypothetical protein	NA	NA	NA	NA
WP_065705443.1\|310965_311604_+	NERD domain-containing protein	A0A2R2ZH57	Clostridioides_phage	4.3e-23	36.6
WP_000665869.1\|311901_312651_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_000274543.1\|314027_314990_+	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
WP_000022653.1\|315720_316152_+	disulfide bond formation protein B	NA	NA	NA	NA
WP_000210396.1\|316232_316523_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065705444.1\|317119_323803_+	DNRLRE domain-containing protein	NA	NA	NA	NA
WP_065705673.1\|323826_324180_+	hypothetical protein	NA	NA	NA	NA
WP_065705446.1\|324738_324951_+	hypothetical protein	NA	NA	NA	NA
WP_065705447.1\|324996_325389_+	hypothetical protein	NA	NA	NA	NA
WP_065705449.1\|325530_326649_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	1.4e-170	80.4
WP_065705451.1\|327303_327597_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065705453.1\|327919_328303_+	(deoxy)nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
WP_065705455.1\|328925_329357_+	hypothetical protein	NA	NA	NA	NA
WP_065705457.1\|329397_330387_+	DUF4065 domain-containing protein	Q9AZG0	Lactococcus_phage	4.7e-16	27.2
WP_065705461.1\|330915_331224_+	hypothetical protein	NA	NA	NA	NA
WP_065705463.1\|331462_331777_-	hypothetical protein	NA	NA	NA	NA
WP_065705674.1\|331982_332579_-	hypothetical protein	NA	NA	NA	NA
WP_065705440.1\|332777_333896_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	2.9e-171	80.4

DBSCAN-SWA_4

408606 : 446600

Bacillus_phage(50.0%)

protease,transposase,integrase,coat

attL 445304:445320|attR 455041:455057

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065705682.1\|408606_409557_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_065705558.1\|409925_410372_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_081306193.1\|410784_412128_-	hypothetical protein	NA	NA	NA	NA
WP_065705562.1\|413127_414711_-	hypothetical protein	NA	NA	NA	NA
WP_065705563.1\|415034_415511_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_065705565.1\|416215_416725_-	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
WP_065705567.1\|416892_417654_-	glycosyltransferase	NA	NA	NA	NA
WP_065705684.1\|418401_419271_-	hypothetical protein	NA	NA	NA	NA
WP_065705569.1\|419395_420379_-	hypothetical protein	NA	NA	NA	NA
WP_065705571.1\|423167_423989_-	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	8.0e-54	45.2
WP_065705573.1\|424185_425475_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.1e-76	35.6
WP_065705575.1\|425471_426425_+	NAD-dependent epimerase/dehydratase family protein	A0A2K9L0I7	Tupanvirus	7.9e-37	33.6
WP_065705576.1\|426428_427622_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_065705579.1\|428082_428784_-	AAA family ATPase	NA	NA	NA	NA
WP_065705581.1\|428864_429290_-	hypothetical protein	NA	NA	NA	NA
WP_065705582.1\|429291_430350_-\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_065705584.1\|430374_431511_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_065705586.1\|431663_432767_+\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_155759252.1\|433224_433422_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_065705685.1\|433770_434574_+\|protease	CAAX protease	NA	NA	NA	NA
WP_065705588.1\|434963_435410_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_065705590.1\|435605_438488_-	PKD domain-containing protein	NA	NA	NA	NA
WP_065705592.1\|438778_440098_-	septum formation initiator	NA	NA	NA	NA
WP_065705593.1\|440388_441276_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	NA	NA	NA	NA
WP_065705595.1\|443029_444784_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.7e-14	49.5
445304:445320	attL	NA	NA	NA	NA
WP_065705597.1\|445427_446600_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_065705597.1\|445427_446600_-\|integrase	site-specific integrase	NA	NA	NA	NA
455041:455057	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP016590

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016590_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016590_1

189882-190082

Orphan

Consensus_repeat	Method
TCTGTACCTTCTGTTCTTTCAACAGTTTTTGCA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP016590_1

>merge|NZ_CP016590|1|189882-190082|CRISPRCasFinder
TCTGTACCTTCTGTTCTTTCAACAGTTTTTGCAAACTCAGGTTTTGATTCTGTACCTTCCTTTACTGGTAAATTTTTTCCTTCTTGAGAATCTGTGCCTTCTGTTCTTTCAACAGTTTTTGCATGTTCTGGTTTTTCAGGGGCTCCAATTTCAAATCCGGGTTTTGATTCTGTACCTTCTGGTCTTTCAATTGTCTCGCTA

>NZ_CP016590|1|1|189882-190082|CRISPRCasFinder
TCTGTACCTTCTGTTCTTTCAACAGTTTTTGCA	AACTCAGGTTTTGATTCTGTACCTTCCTTTACTGGTAAATTTTTTCCTTCTTGAGAA
TCTGTGCCTTCTGTTCTTTCAACAGTTTTTGCA	TGTTCTGGTTTTTCAGGGGCTCCAATTTCAAATCCGGGTTTTGAT
TCTGTACCTTCTGGTCTTTCAATTGTCTCGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016590.1\|WP_065705901.1\|179586_179823_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016590.1\|WP_065705909.1\|186793_187042_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016590.1\|WP_065705930.1\|206085_208044_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP016590.1\|WP_065705911.1\|187334_187847_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016590.1\|WP_065705927.1\|200662_201430_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP016590.1\|WP_081306213.1\|188329_188584_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234802
NZ_CP016590.1\|WP_065705905.1\|183983_184385_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016590.1\|WP_065705922.1\|193132_193894_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP016590.1\|WP_065705929.1\|202118_202958_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|179522
NZ_CP016590.1\|WP_061660621.1\|197937_198609_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP016590.1\|WP_065705903.1\|182844_183651_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|366312
NZ_CP016590.1\|WP_065705906.1\|185117_185366_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016590.1\|WP_065705923.1\|196918_197941_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|340424
NZ_CP016590.1\|WP_065705932.1\|209028_210030_-\|VanZ-family-protein	unknown	unknown	gnl\|CDD\|377417
NZ_CP016590.1\|WP_065705919.1\|191283_193116_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP016590.1\|WP_065705898.1\|178810_179014_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016590.1\|WP_081306212.1\|179233_179464_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP016590.1\|WP_155759259.1\|189107_189365_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016590.1\|WP_065705925.1\|198690_200673_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP016590.1\|WP_065705934.1\|211319_212270_+\|class-A-beta-lactamase	unknown	unknown	gnl\|CDD\|185339

Protein	Function_ID	Function_description	E-value
NZ_CP016590.1\|WP_065705929.1\|202118_202958_-\|peptidylprolyl-isomerase	gnl\|CDD\|179522	PRK02998, prsA, peptidylprolyl isomerase; Reviewed.	8.00557e-114
NZ_CP016590.1\|WP_065705930.1\|206085_208044_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.32898e-05
NZ_CP016590.1\|WP_081306213.1\|188329_188584_-\|hypothetical-protein	gnl\|CDD\|234802	PRK00601, dut, dUTP diphosphatase.	1.98304e-20
NZ_CP016590.1\|WP_065705927.1\|200662_201430_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	4.56863e-98
NZ_CP016590.1\|WP_065705903.1\|182844_183651_-\|acetyltransferase	gnl\|CDD\|366312	pfam00797, Acetyltransf_2, N-acetyltransferase. Arylamine N-acetyltransferase (NAT) is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Acetylation of these compounds generally results in inactivation. NAT is found in many species from Mycobacteria (M. tuberculosis, M. smegmatis etc) to man. It was the first enzyme to be observed to have polymorphic activity amongst human individuals. NAT is responsible for the inactivation of Isoniazid (a drug used to treat Tuberculosis) in humans. The NAT protein has also been shown to be involved in the breakdown of folic acid.	7.66026e-38
NZ_CP016590.1\|WP_061660621.1\|197937_198609_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.84082e-65
NZ_CP016590.1\|WP_065705925.1\|198690_200673_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	1.42965e-05
NZ_CP016590.1\|WP_065705922.1\|193132_193894_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.63229e-106
NZ_CP016590.1\|WP_065705923.1\|196918_197941_-\|sensor-histidine-kinase	gnl\|CDD\|340424	cd16948, HATPase_BceS-YxdK-YvcQ-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.	1.01085e-44
NZ_CP016590.1\|WP_065705932.1\|209028_210030_-\|VanZ-family-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	2.4749e-09
NZ_CP016590.1\|WP_065705919.1\|191283_193116_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.3649e-05
NZ_CP016590.1\|WP_081306212.1\|179233_179464_+\|transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	0.00015688
NZ_CP016590.1\|WP_065705934.1\|211319_212270_+\|class-A-beta-lactamase	gnl\|CDD\|185339	PRK15442, PRK15442, beta-lactamase TEM; Provisional.	1.65825e-61

>NZ_CP016590.1|WP_155759259.1|189107_189365_-|hypothetical-protein
MTREQHFVYITGAFYFYFDLGLELNFYTKIYIGKGGSSLHKIIYGILILIYTLYSFFVSDGSEVRFIMVLTIVLIFSVVLEKRID
>NZ_CP016590.1|WP_081306213.1|188329_188584_-|hypothetical-protein
MSIPKLKITVGWMNMDSGYRGAVGVLVDNTERLISLNMKAHVIKKGTRIVQGVIAPVVTAHFVEVDELLVSERGAGGFGSTGTK
>NZ_CP016590.1|WP_065705911.1|187334_187847_+|hypothetical-protein
METQTYKYPRQKINGIWLIIAGIAMFLLLIKYNGHPNVWPFIIVYILGMIWQLNPKTREKLAVGPGTPEQKKWSNFSIILLAILVFLIFHFFSNDYRICWLLILLAVGVHFLTFIPVHGKLMLFLSISLIINAFIGLIINNVSLDIFFVIDGLIKILFGGIFIKLSPTNF
>NZ_CP016590.1|WP_065705909.1|186793_187042_+|hypothetical-protein
MTFEDNRKLGIQQGCIVITEQSQYLVVKKNENYSLLNITTAECINFEVSLEHLEEMVQVDLKEKIQDIIPPENIKIVAQNRI
>NZ_CP016590.1|WP_065705906.1|185117_185366_-|hypothetical-protein
MEDFDDELRQIDMDQKDAILVVRAYKRYLAKTDEDREYGTEVIERISNSDTTREDADFTIRCTEVIDNLIDKVFEEKVANKS
>NZ_CP016590.1|WP_065705905.1|183983_184385_-|hypothetical-protein
MKEVVKKEKMIPLQGEEHCNRQADAEQYNAEQCNIERECIKLDQKTVKNRTTEEKWDERCKRAVQLFNQGTEYPDIAKIVGCKVSSLYRELKKRGVLQMPKQAASSKTLRSPIVSAKTKKSRFERYKEYYMYK
>NZ_CP016590.1|WP_065705903.1|182844_183651_-|acetyltransferase
MLTELQKKFFSKLKMPPRENVKFEDLHTILLQMGHLLPYENIDIMEGNTKEFSRENIEEKLLLKNRGGLCYEINSLLYYFLCDCGFNVYRIAGTLYDPKTRKWNPDDGHALIVLQHKCENYIIDAGFASYLPLHPVPFHGDSVTSVTGEYRVRKQNTEKGTHVLEMKKGENGETSHFFDSDLSDTWSIGYAFYLNAINEKKVNAIQNMVIEHPESPVNKANIICKLIEHGHIALTKQSFTETRHGKKIKKEITEKQYHQILKNEFNIF
>NZ_CP016590.1|WP_065705901.1|179586_179823_-|hypothetical-protein
MELTKLEKVIVISTFVQGLGEEFLENSKENHSLKQLLREIEKVFNDSTPDQMREAAESVLEKFIYDLIKENNLSLLKN
>NZ_CP016590.1|WP_081306212.1|179233_179464_+|transcriptional-regulator
MWGRGIGRHRTKLAKFLANYDYSIQDFSKASKVNRNTLGQLCNDKDYVPSPNTMQKIMKIVRKHDSRKQVTDFWHI
>NZ_CP016590.1|WP_065705898.1|178810_179014_-|hypothetical-protein
MLTTFISLGALGALGVTTIGGALLEKHLVKNDYVAAAKLVSDGIYHGIRIGGVCFIGYVFIQIVGMF
>NZ_CP016590.1|WP_065705919.1|191283_193116_-|ABC-transporter-permease
MLFKLSMSGLKSKLQDYIVLLVGLIVSISTFYMFQTLSLNKTFLESSSSIRDIVSIFHIGSFLLAIITFFYILYANSFLVSLRQKEFGMYMMLGAKKHKVTLLMFIETIVLGAASLAIGITVGVGLAEGIGQLLMKQLEFPGEGYQAFYIPSITVTCIFFFALFVLSAIMSSIKLVRFSVLQLVHADAQTERVAVKGKMTVVVAFLGLILLGIGYASLTYIPQAGMAALGLMALGLTTATFGTYLLFGSLLPVMINKLKSNKKRSEKGLNAFTFAQLNFRMNSLANVLATVAMLVALGAGGISGGMAFKNNVIKMVNGSEIYDSVVHNPTTEEKKILNTILFTEKLEYHYKIVGQSIYYLKEDLEKNRPLVLKNSNERAEFGKTKRVSEELPIGANVKKSPQQWSEAFEIIQPYYMYPDHEIKIVDKNMYHSIEGLESTVFIGKTDNFKSYLKEWKQLDELQLTKYTSMKPEELKSKYRMYDSYHGMFSGLMFMGFFVGIAYLAMMASCLMFKVLSGASKDCTRYQMLRKIGVRRELLTQSIYKELFFVFLVPAIVGIVHVLVGMNMFGAILIDPYFRIWLPIVIFVVIYSIYYFITVQLYKRIVLPKKD
>NZ_CP016590.1|WP_065705922.1|193132_193894_-|ABC-transporter-ATP-binding-protein
MTKPVVDVKNVQKVYGKQGENQSHALKGVSFSIQEGEFVGIMGPSGSGKTTLLNVISTLDKATGGVVEIAGTDITTMKQGELSDFRSQKLGFIFQDFNLLENLSIYENIALPLSLQGVPSHNIGPKVEKVADMLGITEILQKYPSEVSGGQKQRSAAARALVHEPAIILGDEPTGALDSKNATSLLDAMTNLNKEQGVSIMMVTHDPYSASYCQRILFIQDGELYKEIHRGGSREEFYKEILDVLADLGTQKA
>NZ_CP016590.1|WP_065705923.1|196918_197941_-|sensor-histidine-kinase
MNLGEFIKDKIVVILSNVLVYIILAGILLTAHVPFIIIFFVFCIWFFPLISYMAIEFIRCKNYYNEINGILENLEKKYLLPEVVKEANFIHGEKLNAILKEVSRDMHENVKYYSDMQLDYREYIETWVHEIKTPIASTKLIIENNQNEITNKIDSQMDRIEGFVEQVLYYSRSNNVNKDYIIKPINLDNVVRNVIKRNYRDFIHKRIKLDIQNIGEIVYSDGKWVEFIINQIIGNSIKYSNNKEQMIRIYSIKKTNSVILTIEDNGVGIVTKDINRVFEKGFTGENGRRFSKSTGMGLYLCEKLCSKLGLKIGIESEVNKGTRVTLIFPLSGMVTFESYF
>NZ_CP016590.1|WP_061660621.1|197937_198609_-|response-regulator-transcription-factor
MKKIILIEDDEIIREELQHFFIKYGYEVKAPTDFNHIIEYIESENADLILLDINLPVFDGYYICREIRKTSDIPIFMVTSRDSDVDELISMNLGADDFITKPYNTEILLARVTNILRRTSGDFKMNHILIYRDFTLNLSNATVTYQDKSVELTKNEVKILSCLINNRGNIVKRDSLIETLWKSDYFVDDSTLTVNINRLRKKLEEIGIENPIATRRSLGYIMP
>NZ_CP016590.1|WP_065705925.1|198690_200673_-|ABC-transporter-permease
MYSKIAIGNVKKSLKDYAIYFLTLTLAVCIFYSFNSIESQKAFMEINASDRKYVPVIMNAISDVSVFVSVILGGLILYANNFLIKKRKKELGIYMTLGMGRRNISRILVTETFLVGIISLVSGLIIGIGVSQGLSTFALKLFDLPINKYKFAISTGAIGKTVLYFGIMFLLVMLFNVYVVSKYKIIDMLTAGRKNEDVKFRNPLIYVITFIMCVALLGYAYVTVLKIGLNYNNPMLMVSILLGILGTLLFFFSLSGFILYVVKKNKKIYFKGLNIFIIKQINSKVNTNFISMSVICFMLFLTMVALSTGISFNRMMDVTTKEITPFDASITLENKDESYTIEDVLNKANFKISNNEKYVSYNVYRTGMEVVDFVPELKDYKNSIDFIKVSDYNKILNLKGEKEITLNNNEILLLSNESLLINSTNERLKNSNKVNIKEKEYSVKKAKVIQENLYTYNVPTNYFTIVINDEFLSGYKITESVLNVNYLDGNREEYNKKYDNVARGFYDENGPKLNINRIAGKSKDEVCAESKGMKTIVLFIGIYIGIVFLITSMAVLALQQLSEASDSIDRYKSLKRIGSNGTMIDKTIFIQTFVYFSLPVILALIHSVVGIYVINNFINAFQQTDITLPALMTGLVFLVVYVGYFYTTYVGYKNIVKSNT
>NZ_CP016590.1|WP_065705927.1|200662_201430_-|ABC-transporter-ATP-binding-protein
MRNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNSDITRLKSNSLDKFRQNELGFVFQDFNLLDTLTAYENIALALTIKGETSSKIDGKIQAVAKYLDIEQVLSKYPYQISGGQKQRVASARAIVTDPSLVLADEPTGSLDSKSARLLLERFESLNKDLKATILMVTHDAFTASYARRILFINDGKIFIELVRGNDSRKEFFTKIIEVITLLGGDDNNVL
>NZ_CP016590.1|WP_065705929.1|202118_202958_-|peptidylprolyl-isomerase
MNKRHIFIGAAMSSILLLSACGNSDNLVTSKSGNLTQEEFNKKLKETAGKPVLQQVMLDKILLDKYKVSDDEAKKKVEELKKQMGDNFKAYLTQAGAKDEDDLKTKIKTQIAFEKAVKASVTEKEMKDYYKPKLKASHILVKDEKTAKEIKEKLNNGEDFAALAKQYSEDPGSKEKGGELPEFGPGEMDSKFEEAAYKLEAGQVSDPIKSSHGYHIIKLTEKKELKPFDQEKDNIRKELEQKRSQDQQWQQQFFKDLFKKADIKITDKDLKDTFKEFEK
>NZ_CP016590.1|WP_065705930.1|206085_208044_-|ABC-transporter-permease
MTFRQLAFNNIIRNKRIYLGYFFSSIFAVMIFFTYGLLFFHPNLKGELAPVSTIMSTFGKIGFQLSYYLIFVFSFLFIFYSVSAFLKNRTKEFGLLMLHGMSHKQFYRLIFFENMLIGIPSILVGIGLGMIFSKLFLLVSGSLLAVEHRLPFYFPLKAIGVTALSFFILFLLISLFTSKMVKMNELVEFIKSEEKPKPEPEVSAGLSLLAIILIGAGYTSVHHSIDAIAINYMSGNEVLLIVGSGVTLIIFGTYIFFHQFCIYVIYNLKNRETTFFKRTNLLVISELAFRMKDNSRTFFMVTIISAVSFTAIGACTAIGNPELAKKETPFAFTYRSDWGNPLEESHIEEIKKQLEESGFSYKLATAKFKITQNDIRLINLSTYNEYAKTLGYEIEKLTNENESIVILPMKKHKSVEDLKPYVLRHGELEVPVTVQKTLTVPELKEMLTKTVIISDAIYNEVLNIKTVDVGISQDYTIYGFIIKNWPETTTVSKNLMKSVGTKLGDSYTFSSLSLKWLELKQQNGLLSITSILVGVVFFAFAISFLYFRLFTDLKRDQEQYQMISKLGLSQKELKKIITTQMMILFFLPIVVAMIHSSFAFLTLHQLGQTISREMSVIQSSIVVLVSFFCIQFIYFLIIRNYYIKRICTKINS
>NZ_CP016590.1|WP_065705932.1|209028_210030_-|VanZ-family-protein
MNIISELFISFAIPTIQLTFLLLLIIIFSYFVVYKKVCKGEKKFTVQQIILLILIIGYYSLALSATSFGRSDDIAYARTIDFDVLSVYKKAWNTFSFSSFFHIIVNIGMLFPLGVLLPLFSNGFQKIKWMLTSAIIASLLIEILEFIMQRGSMELVDLLHNILGMMLGYSVLNIVLILVKKKEKHVQMMKYLFLPITVILIAFGIIISYHMKEFGNMPIDPNTKIDMSHVTIKTSIELKEEGEKKPVYKDSVTKKSPVRDVEILSPKEAFQKLKQGEFEPIGSFNAGDTLFITKYNIDYYTDTKGFSQPIYVFEVHVNDNDKDIWSQPISARK
>NZ_CP016590.1|WP_065705934.1|211319_212270_+|class-A-beta-lactamase
MFILSKFFNITHYKKIVSVVLLSCVTLIGCSNSNTPSESPKQTKQTNPIKQENTGDDSFAKLEKEYDAKLGIYALDTGTNQTVSYRSDDRFAFASTSKSLAVGALLRQNSIEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGPSAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFALGTVLPSEKRELLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNHDKEDAEYDDKLIADATKTVLNILKATNK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP016590_1	1.1\|189915\|57\|NZ_CP016590\|CRISPRCasFinder	189915-189971	57	NZ_CP016590	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-02, complete sequence	189915-189971	1.0
NZ_CP016590_1	1.1\|189915\|57\|NZ_CP016590\|CRISPRCasFinder	189915-189971	57	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	210073-210129	1.0
NZ_CP016590_1	1.2\|190005\|45\|NZ_CP016590\|CRISPRCasFinder	190005-190049	45	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	209995-210039	1.0
NZ_CP016590_1	1.2\|190005\|45\|NZ_CP016590\|CRISPRCasFinder	190005-190049	45	NZ_CP016590	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-02, complete sequence	190005-190049	1.0

1. spacer 1.1|189915|57|NZ_CP016590|CRISPRCasFinder matches to NZ_CP016590 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-02, complete sequence) position: , mismatch: 0, identity: 1.0

aactcaggttttgattctgtaccttcctttactggtaaattttttccttcttgagaa	CRISPR spacer
aactcaggttttgattctgtaccttcctttactggtaaattttttccttcttgagaa	Protospacer
*********************************************************

2. spacer 1.1|189915|57|NZ_CP016590|CRISPRCasFinder matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 0, identity: 1.0

aactcaggttttgattctgtaccttcctttactggtaaattttttccttcttgagaa	CRISPR spacer
aactcaggttttgattctgtaccttcctttactggtaaattttttccttcttgagaa	Protospacer
*********************************************************

3. spacer 1.2|190005|45|NZ_CP016590|CRISPRCasFinder matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 0, identity: 1.0

tgttctggtttttcaggggctccaatttcaaatccgggttttgat	CRISPR spacer
tgttctggtttttcaggggctccaatttcaaatccgggttttgat	Protospacer
*********************************************

4. spacer 1.2|190005|45|NZ_CP016590|CRISPRCasFinder matches to NZ_CP016590 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-02, complete sequence) position: , mismatch: 0, identity: 1.0

tgttctggtttttcaggggctccaatttcaaatccgggttttgat	CRISPR spacer
tgttctggtttttcaggggctccaatttcaaatccgggttttgat	Protospacer
*********************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

21209 : 83110

Bacillus_phage(50.0%)

transposase,protease,integrase

attL 75170:75185|attR 87110:87125

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065705708.1\|21209_21545_+\|transposase	transposase	NA	NA	NA	NA
WP_081306199.1\|21795_22131_+	hypothetical protein	NA	NA	NA	NA
WP_065705710.1\|22611_22791_+	DUF4083 domain-containing protein	NA	NA	NA	NA
WP_065705712.1\|22846_23233_+	DUF5412 domain-containing protein	NA	NA	NA	NA
WP_065705714.1\|23426_24137_-	hypothetical protein	D2XR34	Bacillus_phage	7.9e-34	91.4
WP_002166598.1\|24675_25029_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065706015.1\|25072_25678_+	hypothetical protein	NA	NA	NA	NA
WP_065705716.1\|26067_26598_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_065705718.1\|26601_27549_+	DUF4179 domain-containing protein	NA	NA	NA	NA
WP_065705720.1\|28133_28805_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_085963828.1\|29046_30209_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.7e-33	42.6
WP_065705722.1\|32598_32823_+	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_065705724.1\|33147_33741_-	cell division protein FtsN	NA	NA	NA	NA
WP_155759253.1\|34905_36247_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.1e-31	37.1
WP_065705730.1\|36912_37320_-	DUF4870 domain-containing protein	NA	NA	NA	NA
WP_065705732.1\|37508_37757_-	hypothetical protein	A0A288WFY7	Bacillus_phage	5.0e-36	93.9
WP_065705734.1\|39134_39839_+	response regulator transcription factor	NA	NA	NA	NA
WP_065705736.1\|39838_40825_+	sensor histidine kinase	NA	NA	NA	NA
WP_065706018.1\|40967_41738_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.0e-32	40.4
WP_065705738.1\|41712_43683_+	ABC transporter permease	NA	NA	NA	NA
WP_065705740.1\|43715_44459_+	hypothetical protein	NA	NA	NA	NA
WP_065705742.1\|45513_46047_+	sigma-70 family RNA polymerase sigma factor	A0A0F6TH34	Sinorhizobium_phage	1.5e-05	25.7
WP_065705744.1\|46036_46867_+	anti-sigma factor	NA	NA	NA	NA
WP_065705745.1\|46884_48639_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_065705747.1\|49286_49616_+	Invasion protein IagB domain protein	NA	NA	NA	NA
WP_065705749.1\|49977_51084_+	acyltransferase	NA	NA	NA	NA
WP_065705751.1\|51247_51892_+	hypothetical protein	A0A223LKM8	Bacillus_phage	1.5e-15	34.0
WP_065705753.1\|52315_53500_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_065703200.1\|56190_57420_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	1.7e-84	48.8
WP_065705755.1\|57784_57982_+	hypothetical protein	NA	NA	NA	NA
WP_065705759.1\|59139_59760_-	HAD family hydrolase	NA	NA	NA	NA
WP_065705761.1\|59779_60544_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_065705763.1\|60913_62266_+	ABC transporter permease	NA	NA	NA	NA
WP_154698409.1\|62912_63086_+	hypothetical protein	NA	NA	NA	NA
WP_065705767.1\|66265_66916_-	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_065705769.1\|67115_67508_-	hypothetical protein	NA	NA	NA	NA
WP_065705771.1\|67958_68186_-	hypothetical protein	NA	NA	NA	NA
WP_065705773.1\|68442_69447_-	VanZ family protein	NA	NA	NA	NA
WP_155759254.1\|71427_71679_-	hypothetical protein	NA	NA	NA	NA
WP_065705775.1\|71830_72958_-	Ger(x)C family spore germination protein	NA	NA	NA	NA
WP_065705777.1\|72954_74058_-	endospore germination permease	NA	NA	NA	NA
WP_065705779.1\|74044_75553_-	spore germination protein	NA	NA	NA	NA
75170:75185	attL	NA	NA	NA	NA
WP_065705781.1\|76604_77930_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_065705783.1\|78197_79655_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_065706020.1\|79824_80754_+	glutaminase A	NA	NA	NA	NA
WP_065705785.1\|81473_81722_+	hypothetical protein	NA	NA	NA	NA
WP_065705787.1\|81949_83110_-\|integrase	site-specific integrase	NA	NA	NA	NA
87110:87125	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP016588

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP016589

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP016590

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection