CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP016276	Yersinia pestis strain Cadman plasmid pPCP1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP016275	Yersinia pestis strain Cadman plasmid pMT1, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP016273	Yersinia pestis strain Cadman chromosome, complete genome	5 crisprs	DinG,DEDDh,cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,csa3	5	8	18	1
NZ_CP016274	Yersinia pestis strain Cadman plasmid pCD1, complete sequence	0 crisprs	NA	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

19306 : 82009

Salmonella_phage(85.71%)

transposase,terminase,tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211746.1\|19306_19813_+	antirestriction protein ArdA	A0A1I9S7Y0	Rhodococcus_phage	1.1e-08	29.5
WP_002211745.1\|20525_20756_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_002211744.1\|20828_22838_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	7.7e-26	30.3
WP_000255944.1\|22961_23984_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|23983_24763_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002425587.1\|25332_25758_+	hypothetical protein	J9Q7S4	Salmonella_phage	7.5e-72	100.0
WP_002213141.1\|25787_26351_-	DNA-binding protein	J9Q7G7	Salmonella_phage	2.2e-63	64.6
WP_002215095.1\|26423_26675_-	hypothetical protein	NA	NA	NA	NA
WP_002213135.1\|26895_27327_+	hypothetical protein	J9Q6I8	Salmonella_phage	2.6e-72	98.6
WP_002213132.1\|27446_28475_+	hypothetical protein	J9Q7Z3	Salmonella_phage	1.3e-165	98.5
WP_002225551.1\|28535_29480_+	exonuclease	J9Q7S6	Salmonella_phage	1.3e-180	99.0
WP_000920226.1\|29479_29746_+	hypothetical protein	J9Q7G8	Salmonella_phage	1.6e-40	100.0
WP_002213439.1\|30915_31116_+	hypothetical protein	J9Q6J0	Salmonella_phage	1.1e-25	97.0
WP_002222866.1\|31119_31950_+	hypothetical protein	J9Q7Z4	Salmonella_phage	9.3e-127	98.6
WP_002222868.1\|32103_32475_+	DUF2591 domain-containing protein	J9Q7S7	Salmonella_phage	4.0e-61	87.8
WP_002222869.1\|32458_32869_+	hypothetical protein	J9Q7G9	Salmonella_phage	4.1e-75	97.8
WP_002228797.1\|32936_33212_+	hypothetical protein	J9Q738	Salmonella_phage	1.7e-45	95.6
WP_002228796.1\|33252_33432_+	hypothetical protein	J9Q6J1	Salmonella_phage	5.8e-18	86.4
WP_002227818.1\|33428_33764_+	hypothetical protein	J9Q7Z5	Salmonella_phage	5.2e-52	91.0
WP_002222711.1\|33763_33976_+	hypothetical protein	J9Q7S8	Salmonella_phage	6.8e-34	95.7
WP_002214164.1\|34544_35609_-	replication protein RepA	J9Q7H0	Salmonella_phage	2.4e-188	98.6
WP_002214160.1\|36353_36998_+	hypothetical protein	J9Q739	Salmonella_phage	1.8e-122	98.1
WP_002213298.1\|37357_38380_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002213300.1\|38795_39881_+	metallophosphoesterase	J9Q7S9	Salmonella_phage	7.7e-206	98.6
WP_002214148.1\|40110_42027_+	AAA family ATPase	J9Q741	Salmonella_phage	0.0e+00	98.6
WP_002213303.1\|42016_42763_+	hypothetical protein	J9Q6J5	Salmonella_phage	4.1e-134	96.4
WP_002214145.1\|42775_43345_+	hypothetical protein	J9Q7Z7	Salmonella_phage	5.8e-104	100.0
WP_002213759.1\|43553_44012_+\|transposase	IS200/IS605-like element IS1541A family transposase	D9CGB6	Hyperthermophilic_Archaeal_Virus_2	5.0e-13	35.3
WP_002211802.1\|44211_44493_+	hypothetical protein	J9Q753	Salmonella_phage	6.1e-46	93.5
WP_002211801.1\|44698_45181_+	hypothetical protein	J9Q805	Salmonella_phage	5.1e-85	94.4
WP_002214137.1\|45819_46047_-	hypothetical protein	NA	NA	NA	NA
WP_002211799.1\|46131_46782_-	hypothetical protein	J9Q754	Salmonella_phage	4.1e-114	99.5
WP_002214134.1\|47103_47631_-	transcriptional regulator	J9Q6L0	Salmonella_phage	6.4e-81	98.0
WP_002211796.1\|47635_48058_-	hypothetical protein	J9Q806	Salmonella_phage	4.1e-62	85.0
WP_002214131.1\|48117_48396_-	hypothetical protein	J9Q7T9	Salmonella_phage	4.4e-41	97.8
WP_002211794.1\|48398_49958_-	DEAD/DEAH box helicase	J9Q7I4	Salmonella_phage	1.1e-293	99.0
WP_002228791.1\|50022_50721_+	ParB N-terminal domain-containing protein	J9Q756	Salmonella_phage	9.6e-125	98.7
WP_002211792.1\|50720_51389_+	ParB N-terminal domain-containing protein	J9Q6L1	Salmonella_phage	9.5e-114	98.2
WP_002211791.1\|51385_52024_+	ATP-binding cassette domain-containing protein	J9Q807	Salmonella_phage	4.7e-110	98.1
WP_002211790.1\|52016_52271_+	hypothetical protein	J9Q7U0	Salmonella_phage	2.0e-40	97.6
WP_002211789.1\|52276_53167_+	hypothetical protein	J9Q7I6	Salmonella_phage	6.2e-169	99.7
WP_000176291.1\|53176_53443_+	hypothetical protein	J9Q757	Salmonella_phage	1.3e-42	100.0
WP_002211788.1\|53638_54280_+	hypothetical protein	J9Q6D4	Salmonella_phage	1.2e-108	98.1
WP_002211787.1\|54282_55539_+\|terminase	terminase	J9Q7Y2	Salmonella_phage	1.8e-251	100.0
WP_002211786.1\|55572_57147_+	hypothetical protein	J9Q7R1	Salmonella_phage	2.4e-301	99.2
WP_002211785.1\|57169_58003_+	hypothetical protein	J9Q7F4	Salmonella_phage	5.8e-137	91.3
WP_002211784.1\|58029_58905_+	hypothetical protein	J9Q710	Salmonella_phage	8.5e-163	99.7
WP_002211783.1\|58979_59642_+	Ig domain-containing protein	J9Q6D6	Salmonella_phage	8.5e-107	97.2
WP_002211782.1\|59685_60120_+	hypothetical protein	J9Q7Y3	Salmonella_phage	3.1e-73	99.3
WP_002211781.1\|60119_60953_+	hypothetical protein	J9Q7R2	Salmonella_phage	2.9e-152	99.6
WP_001027662.1\|61050_61395_+	hypothetical protein	J9Q7F6	Salmonella_phage	1.9e-57	100.0
WP_002211780.1\|61385_61859_+	hypothetical protein	J9Q711	Salmonella_phage	8.9e-82	99.4
WP_002211779.1\|61860_62244_+	hypothetical protein	J9Q6D8	Salmonella_phage	1.1e-66	98.4
WP_002211778.1\|62318_63065_+	Ig domain-containing protein	J9Q7Y4	Salmonella_phage	5.2e-129	98.8
WP_000163862.1\|63124_63442_+	hypothetical protein	J9Q7R3	Salmonella_phage	6.0e-50	98.1
WP_000952684.1\|63567_63792_+	hypothetical protein	J9Q7F7	Salmonella_phage	4.2e-34	100.0
WP_002211776.1\|63799_68377_+	tape measure protein	J9Q712	Salmonella_phage	0.0e+00	90.5
WP_000440566.1\|68418_68754_+\|tail	phage tail protein	J9Q6E1	Salmonella_phage	5.7e-59	97.3
WP_002211775.1\|68843_69542_+\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	7.1e-136	99.1
WP_002211774.1\|69534_70332_+	C40 family peptidase	J9Q7R4	Salmonella_phage	1.4e-156	96.2
WP_002211773.1\|70319_70907_+\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	5.1e-103	92.8
WP_002214118.1\|70928_75560_+	DUF1983 domain-containing protein	J9Q713	Salmonella_phage	0.0e+00	88.6
WP_002211771.1\|75616_76195_+	DUF4376 domain-containing protein	Q9LA61	Enterobacterial_phage	3.4e-27	38.8
WP_002211770.1\|76275_79164_+\|tail	phage tail protein	J9Q6E3	Salmonella_phage	4.5e-11	33.1
WP_002211769.1\|79465_80074_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	4.8e-64	62.2
WP_001297096.1\|80207_80987_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|80986_82009_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP016273

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016273_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016273_1

214655-214767

Orphan

Consensus_repeat	Method
CTTCACTCGGCTGCTCAAATGTGCTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP016273_1

>merge|NZ_CP016273|1|214655-214767|CRISPRCasFinder
CTTCACTCGGCTGCTCAAATGTGCTTTGGACGTCAACAACCCATTCAAAATCAAAAACGTATTAAAAGCCTAAGGATGATGGTCTGGCTTCACTCGCTGCTCAAATGTGCTTT

>NZ_CP016273|1|1|214655-214767|CRISPRCasFinder
CTTCACTCGGCTGCTCAAATGTGCTTT	GGACGTCAACAACCCATTCAAAATCAAAAACGTATTAAAAGCCTAAGGATGATGGTCTG
GCTTCACTCGCTGCTCAAATGTGCTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016273.1\|WP_002209484.1\|226409_227027_+\|heme-acquisition-protein-HasA	unknown	unknown	gnl\|CDD\|368907
NZ_CP016273.1\|WP_002209491.1\|215186_217823_-\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|234570
NZ_CP016273.1\|WP_002209498.1\|203166_204597_+\|glycogen-synthase-GlgA	unknown	unknown	gnl\|CDD\|234809
NZ_CP016273.1\|WP_002209489.1\|219610_220615_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NZ_CP016273.1\|WP_002209499.1\|199670_201659_+\|glycogen-debranching-protein-GlgX	unknown	unknown	gnl\|CDD\|235152
NZ_CP016273.1\|WP_002209497.1\|204765_207213_+\|glycogen-phosphorylase	unknown	unknown	gnl\|CDD\|184948
NZ_CP016273.1\|WP_002209500.1\|197485_199669_+\|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl\|CDD\|235445
NZ_CP016273.1\|WP_002223919.1\|218196_219360_-\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|235346
NZ_CP016273.1\|WP_002209496.1\|207375_208797_-\|glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|237027
NZ_CP016273.1\|WP_002209495.1\|209878_210343_+\|DUF943-family-protein	unknown	unknown	gnl\|CDD\|368741
NZ_CP016273.1\|WP_002209494.1\|210507_210777_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016273.1\|WP_002215335.1\|220780_221557_+\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|239782
NZ_CP016273.1\|WP_000255944.1\|212371_213394_+\|IS21-like-element-IS100-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_CP016273.1\|WP_001297096.1\|213393_214173_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
NZ_CP016273.1\|WP_002209482.1\|229076_230405_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NZ_CP016273.1\|WP_079993164.1\|209718_209895_+\|DUF3289-family-protein	unknown	unknown	gnl\|CDD\|132079
NZ_CP016273.1\|WP_002209483.1\|227192_229001_+\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NZ_CP016273.1\|WP_002209487.1\|221723_223097_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179883
NZ_CP016273.1\|WP_002209481.1\|230469_231273_+\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NZ_CP016273.1\|WP_002209485.1\|223695_226188_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273807

Protein	Function_ID	Function_description	E-value
NZ_CP016273.1\|WP_002209484.1\|226409_227027_+\|heme-acquisition-protein-HasA	gnl\|CDD\|368907	pfam06438, HasA, Heme-binding protein A (HasA). Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted hemophore that has the ability to obtain iron from hemoglobin. Once bound to HasA, the heme is shuttled to the receptor HasR, which releases the heme into the bacterium.	9.51098e-102
NZ_CP016273.1\|WP_002209491.1\|215186_217823_-\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NZ_CP016273.1\|WP_002209498.1\|203166_204597_+\|glycogen-synthase-GlgA	gnl\|CDD\|234809	PRK00654, glgA, glycogen synthase GlgA.	0
NZ_CP016273.1\|WP_002209499.1\|199670_201659_+\|glycogen-debranching-protein-GlgX	gnl\|CDD\|235152	PRK03705, PRK03705, glycogen debranching protein GlgX.	0
NZ_CP016273.1\|WP_002209497.1\|204765_207213_+\|glycogen-phosphorylase	gnl\|CDD\|184948	PRK14986, PRK14986, glycogen phosphorylase; Provisional.	0
NZ_CP016273.1\|WP_002209500.1\|197485_199669_+\|1,4-alpha-glucan-branching-protein-GlgB	gnl\|CDD\|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NZ_CP016273.1\|WP_002223919.1\|218196_219360_-\|acetylornithine-deacetylase	gnl\|CDD\|235346	PRK05111, PRK05111, acetylornithine deacetylase; Provisional.	0
NZ_CP016273.1\|WP_002209496.1\|207375_208797_-\|glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|237027	PRK12266, glpD, glycerol-3-phosphate dehydrogenase; Reviewed.	0
NZ_CP016273.1\|WP_002209495.1\|209878_210343_+\|DUF943-family-protein	gnl\|CDD\|368741	pfam06092, DUF943, Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi.	1.80736e-84
NZ_CP016273.1\|WP_002209489.1\|219610_220615_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NZ_CP016273.1\|WP_002215335.1\|220780_221557_+\|acetylglutamate-kinase	gnl\|CDD\|239782	cd04249, AAK_NAGK-NC, AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of ornithine biosynthesis. There are two variants of this pathway. In one, typified by the pathway in Escherichia coli, glutamate is acetylated by acetyl-CoA and acetylornithine is deacylated hydrolytically. In this pathway, feedback inhibition by arginine occurs at the initial acetylation of glutamate and not at the phosphorylation of NAG by NAGK. Homodimeric NAGK-NC are members of the Amino Acid Kinase Superfamily (AAK).	2.52737e-136
NZ_CP016273.1\|WP_000255944.1\|212371_213394_+\|IS21-like-element-IS100-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.49492e-79
NZ_CP016273.1\|WP_001297096.1\|213393_214173_+\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	5.26232e-178
NZ_CP016273.1\|WP_002209482.1\|229076_230405_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	3.16318e-105
NZ_CP016273.1\|WP_079993164.1\|209718_209895_+\|DUF3289-family-protein	gnl\|CDD\|132079	TIGR03034, TIGR03034, conserved hypothetical protein. Members of this protein family have been found in several species of gammaproteobacteria, including Yersinia pestis and Y. pseudotuberculosis, Xylella fastidiosa, and Escherichia coli UTI89. As many as five members can be found in a single genome. The function is unknown. [Hypothetical proteins, Conserved].	5.70966e-16
NZ_CP016273.1\|WP_002209483.1\|227192_229001_+\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_CP016273.1\|WP_002209487.1\|221723_223097_+\|argininosuccinate-lyase	gnl\|CDD\|179883	PRK04833, PRK04833, argininosuccinate lyase; Provisional.	0
NZ_CP016273.1\|WP_002209481.1\|230469_231273_+\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	1.51188e-39
NZ_CP016273.1\|WP_002209485.1\|223695_226188_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	8.20794e-132

>NZ_CP016273.1|WP_001297096.1|213393_214173_+|AAA-family-ATPase
MMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGVMAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTSAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE
>NZ_CP016273.1|WP_000255944.1|212371_213394_+|IS21-like-element-IS100-family-transposase
MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEPPKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIRSLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMRYDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVANQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDSFCRGVA
>NZ_CP016273.1|WP_002209494.1|210507_210777_+|hypothetical-protein
MLTDRDIEKTPKITRDYYFEYQPGDGYNPSSTIIFNHTLDASPLKNYLNSLGYERQSQILVIVKCGHYQAKRHNPLSISGWIRRTIKFG
>NZ_CP016273.1|WP_002209495.1|209878_210343_+|DUF943-family-protein
MKVKSKKNLWALLLTGSALLGYVFWLLLHPVEIVSVHQRNDYSDVLVRNFPLTDKSKINWWLENRDMLKDKYSIPKPASDGFYTVIFWDFGDGYKEEGKYDRRCFDDMKTSKNCIDKNKVFSVENDRDKDILFSVYDGMYRLEKNGKIVKMKRE
>NZ_CP016273.1|WP_079993164.1|209718_209895_+|DUF3289-family-protein
MKRSYLDNDNIKNSTFNGFNLFRIGFVLQRFNQFSFKPFMTNMEATVEIAGSRNESKK
>NZ_CP016273.1|WP_002209496.1|207375_208797_-|glycerol-3-phosphate-dehydrogenase
METKDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKLAPHIAFPMRFRLPHQPHLRPAWMIRTGLFLYDHLGKRTSLPASKGLRFGPESVLKPELVRGFEYSDCWVDDARLVVLNVQEVVKHGGEVRTRTKVTRTWREQGLWMVEALDVNTGKTFTWRAKGLVNATGPWVKQFFDDGLKLKSPYGIRLIKGSHIVVPRVHNQPQAYILQNEDHRIVFVIPWLDDYSIIGTTDVEYHGDPKEVKIDDQEMTYLLKVYNDHFKKQLGRDDIVWTYSGVRPLCDDESDSPQAVTRDYTLDVADEAGQAPLLSVFGGKLTTYRKLAEHALEKLSAYYPNVGPAWTKTGALPGGDIGGSRDSYTVQLRHRYNWLPEGLARRYTRTYGSHSELILANATRLESLGEHFGHGLYEAELRYLVENEWVVELDDAIWRRTKLGMALSDEEKQRVAQWLADAHTEKQQALPLVS
>NZ_CP016273.1|WP_002209497.1|204765_207213_+|glycogen-phosphorylase
MTSPFSYTSPVVSVDALKHSIAYKLMFIIGKDPTIATQHDWLNATLFAVRDRMVERWLRSNRAQLSQDVRQVYYLSMEFLLGRTLSNALLSMGIYDEIEQALDEMGLSLSELLKEENDPGLGNGGLGRLAACFLDSLATLALPGRGYGIRYEYGMFSQKIVNGQQMESPDNWLEYGNAWEFPRHNTRYKVRFGGRIQQEGSKIRWLETEEILACAYDQIIPGFDTDATNTLRLWSAQASNEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSATVQDILNRHWAMHHTFNNLADKIAIHLNDTHPVLSIPEMMRLLIDEHKFTWMDAWDVVQQVFSYTNHTLMSEALETWPVDMIGKILPRHLQIIFDINDHFLKLVEEQYPDDKELLSRVSVIDENNGRRIRMAWLAVIASHKVNGVSALHSELMVQSLFADFARIFPNRFCNKTNGVTPRRWLGLANRPLAAVLDDSIGQTWRTDLSQLSELEKNLDYPSFLLALQKAKLENKKRLAVYIAEKLNIVVNPAALFDVQIKRIHEYKRQLLNVLHVITRYNRIIDAPDNNWVPRVVIFAGKAASAYYNAKQIIHLINDVAKVINNDPRINNLLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEIREHVGEENIFIFGNTTEQVEALRKSGYNPRKYYDEDPELHQVLTQIATGTFSPEEPHRYTNLFDSLVNLGDHYQLLADYRSYVDTQEQVDALYRNRDEWSRKTLLNIANMGYFSSDRTIKEYADEIWHIKPIRL
>NZ_CP016273.1|WP_002209498.1|203166_204597_+|glycogen-synthase-GlgA
MRVLHVCSELFPLLKTGGLADVIGALPAAQLAEGADVRIILPAFPDLRRGIPETVLVREIDTFAGRVALRYGHYRGIGIYLIDAPALYDRAGSPYHDASLYAYSDNYLRFALLGWMACELACGLDGYWRPEVVHAHDWHAGLTCAYLAARGRPARSVFTVHNLAYQGLFSADHLSELHLPAEFFQIYGLEFYGQISYLKAGLFFADHVTTVSPTYAKEITQPAFGYGMEGLLQALARQGRLTGILNGVDSDIWDPQSDTLLPTRYDAENLQAKAINKTHLQTAMGLQLAENKPIFAVVSRLTVQKGLDLVLEALPELLALGGQLVVLGSGDATLQEAFLAAAAEHSGQVGVQIGYHEAFSHRIIAGSDVILVPSRFEPCGLTQLYGLKYGTLPLVRHTGGLADTVVDCALENLADGSASGFVFNECEAQALVKAIRRAFVLWSRPKHWRHVQRHAMRLDFGWQLAAVDYLSLYRRL
>NZ_CP016273.1|WP_002209499.1|199670_201659_+|glycogen-debranching-protein-GlgX
MAVLTHGSPTPSGAHFDGKGINFTLFSAHAEQVTLCLFDEQGQERQIAMPARTGDIWHGYLPGGKPGQRYGYRVSGPFEPSRGHRFNPHKLLIDPRTRALEGKVGDDPRFTGGVSQPDVRDSAAALPKCLVIHEEYDWQGDKPPAIPWGNTVIYEAHVRGLTQLHPDIPPELRGTYAALAHPALIEHLKTLGITTLELLPVQFHIDEPRLQKMGLSNYWGYNVLAPFAVDPDYASGREGISPLRELRDAVKALHNAGIEVILDVVFNHSAELDVFGPTLCQRGIDNASYYWLTPDGEYDNITGCGNALRLSHPYVTQWVIDCLNYWRDSCHVDGFRFDLGTVLGRTPAFDQHAPLFAALAADERLSACKLIAEPWDIGLGGYQLGNFPTGFSEWNDQYRDAMRGFWLRGEVPRGTFAQHFAASSRLFEQRGRLPSASINQITAHDGFTLLDLLCFNQKHNQMNGEENRDGSDNNHSNNFGCEGLVADAAIWQRRKACQRALLTTLLLSQGTPMLLAGDEQGHSQQGNNNAYCQNNILTWLDWGSADRALMTFTADLIRLRQQIPALTQDQWWQSGDSNVQWLDSQGQALSDAAWEQGCQQQLQILLSQRWLVLINATDHECEMHLPEGEWEGIPPFGVSDHAERLTTWRGSAHTICVLIKRD
>NZ_CP016273.1|WP_002209500.1|197485_199669_+|1,4-alpha-glucan-branching-protein-GlgB
MSVLPDRQVINQLISGHYGDPFSILGMHETSQGLQICALLPDAREVWLVETENGRRIAQLTLEDPRGFFIAQLTRRKKSFRYQFAVTWQENPQIIEDPYRFGPLLQDIDSWLLAEGTHLRPYERLGAHLMSLDGVSGVSFAVWAPNAQRVSVVGDFNFWDGRRHPMRLRRENGIWELFLPGIEAGQLYKFEIIDCHGQVRLKADPYAFEAQMRPETASLISPLPDVVKSSAARQKANDLCSPVSIYEVHLGSWRRHTDNNFWLSYRELADQLVEYVKYMGFTHVELLPINEHPFDGSWGYQPLGLYAPTRRYGTPEDFKAFVAKFHQAGINVILDWVPGHFPSDEHGLSTFDGTALYEYADPREGYHQDWNTLIYNYGRNEVRNYLAGNAFYWMERFGIDALRIDAVASMIYRDYSRAEGQWVPNYYGGRENLEAIAFLRYTNKTIGVERPGSVTMAEESTDFPGVTLPPDIGGLGFNYKWNMGWMHDTLNYMQCDPVHRKYHHNLMTFGMLYAYTENFILPLSHDEVVHGKRSILDRMPGDAWQKFANLRAYYAFMWAHPGKKLLFMGCEFAQGREWNFETSLDWHLLDDENGWHSGVQRLVRDLNHCYRQYAPLYEWDYQPAGFEWLVVDDHENSVFAFLRRDAEGHELIAISNFTPVPRYHYRVGIPQGGHYREVLNSDSAFYCGSNLGNQGGIDSHHVRSHNHEHSLLLTLPPLATIYLLREN
>NZ_CP016273.1|WP_002209491.1|215186_217823_-|phosphoenolpyruvate-carboxylase
MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKQDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
>NZ_CP016273.1|WP_002223919.1|218196_219360_-|acetylornithine-deacetylase
MKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIPYPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
>NZ_CP016273.1|WP_002209489.1|219610_220615_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSDLHPQLKGILDLPLQPLVDVAQAAKGIDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQLALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVTHLGTPVIFTPHLGNFARGILATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQCMNIRFGFPETQSLL
>NZ_CP016273.1|WP_002215335.1|220780_221557_+|acetylglutamate-kinase
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHSEQLPALFNGVPIGTRISV
>NZ_CP016273.1|WP_002209487.1|221723_223097_+|argininosuccinate-lyase
MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
>NZ_CP016273.1|WP_002209485.1|223695_226188_+|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MDNIIRDKKTIISVNKITTCILFALVTQGYSGQLAANTAETPTNNNDMALDKLNVEGKGNAHDSDWIYDEPRSVSEITREQLDNRPARHAADILEQTPGVYSSVSQQDPGLSINIRGIQDYGRVNMNIDGMRQNFMKSGHGQRNGSMYIDPEILSNVVIERGIFNGIGGAGAIGGIATFNTINASDFLAPEKELGGHIRAMTGDNGTRFIGSGALALGNPNGDILLAVSERNLKDYWPGNKGVLAGLRLYSPTRNVGDDLKNTKTLFTGYKMRSQLAKVGWNFEAGQRLEFSYLQTQIASPNASMLSEVLALSPSGKEITKIGWRNTSFTNVENRNIALDYRLNPEHISWLDATAKIYYVDTNDETDNANSLFKEYFWTQTRLKTRGLQLQNTNTFTPSDAHQIRLKYGLEWFSDKSEGYSTRKLIERTTPPGKRAITSTFAQLNYEYDDWLRLEGGLRYDQFRLKGNTWLHTRSFLQPYTFENPCDRRIHEQSEKPGSRCSSRRPATMRWDVDRCEQQLSPTLAMGVKPGLEWLEFFGSYGKSWRPPAMTEVLATGTAHGYSWVLPNPFVAAERARTWEAGFNIQQSNLFIEDDHFAAKVAYFDTRIANYINLELGKAKPKFGGDSFTDVAYVNNLLKTRFRGLEYQLSYDAGTFYTNINYTRMIGVNNVCSPYAWLGGLQSVKYKYVGKVEQIYAVENEVANNYVTCMNANVLFGSSAYLPGDRGSLTLGSRIFDRRLDFGTVIRYNKGYQDRSAQDENGNPLTAYVADWPKYIVYDLYASYKVTNNLILRSSIENITNRAYLVNYGDTLSFAPSRGRTIQGGFEYKF
>NZ_CP016273.1|WP_002209484.1|226409_227027_+|heme-acquisition-protein-HasA
MSTTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKYSFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPDSGYMSDAPMVDTVGVVDCHDMLLAA
>NZ_CP016273.1|WP_002209483.1|227192_229001_+|type-I-secretion-system-permease/ATPase
MESCKTPGASSVPPTILSVLAGNKKILWGIGLFTAVINLLMLAPAIYMLQVYDRVLASANTMTLLMLTVLVLGVFVFIGLLEWVRSAVVIRLGTQIDMQLNQPVFNAAFAANLKGHNTPAAQALNDLTVLRQFATGNALFAFFDAPWFPLYLLVIFLLHPWLGMLAAAGAGILVVLAWLNQWICKKPLHDASIITSHATQQANANLRNADVIEAMGMLKALRERWLMQHANFLYQQNLASDKSSRVTAVAKSSRQALQSMMLGLGALLVIYNEITAGVMIAGSILIGRVLGPIDQLIAVWKQWSHARLAYQRLSQLLAQHPSSPTGMVLPAPQGKLNVTQLMACKPGTHIPVLHSINFELQPGDVLGILGPSGSGKSTLAKLLVASQPTFSGTVRLDSADLSRWDKTQLGEFIGYLPQNIQLFRGTVAENIARFGAIDTAKVVAAAQLADVHDLILHLPQGYDTPLGDDGEGLSGGQRQRIALARAMYGIPRLIVLDEPNASLDKEGEQALLASIIQLKQQGCTIVMITHKPELLSGSDYLLFLKNGQMDLFDRTQAVLQNIQGKDKPAVQPEAKILNSRSGWSNGVSYGIGPARTTSSPKP
>NZ_CP016273.1|WP_002209482.1|229076_230405_+|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQSTSDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLDPTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE
>NZ_CP016273.1|WP_002209481.1|230469_231273_+|energy-transducer-TonB
MNRLQQSSDKLIFWLVGALLACGIHIYALWWLSTASIPAIPTSYPAAIMMELSAEPEFMQNLPQNSVVGITQNIIEPAVEQRVNQPDDIVDLPTLPEQPEGQREITRKEPIKVKRPAENRATSRKPVNKETQESDSKQSSPAAAASAMLSGTSQQVAAAVNSDSSHRQQAQVSWKSRLQGHLMGFKRYPSSARKQQQQGTAMIRFVVDKNGYVSSVQLSHSSGTSALDREALAIIKRAQPLPKPPAELLSQGQITLSLPVDFNLKRK

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Crispr_ID: NZ_CP016273_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016273_2

1381142-1381263

Orphan

Consensus_repeat	Method
CTTAATGCCAATATTAATCGACATAATCAATTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP016273_2

>merge|NZ_CP016273|2|1381142-1381263|CRISPRCasFinder
CTTAATGCCAATATTAATCGACATAATCAATTGTAGTGGAGGGGGAGGATTGAGTTTTTTCCAAAAAAACATATTGCAGTATTAAATCTCTTAATGCCAATATTAATCGATATAATCAATTG

>NZ_CP016273|2|2|1381142-1381263|CRISPRCasFinder
CTTAATGCCAATATTAATCGACATAATCAATTG	TAGTGGAGGGGGAGGATTGAGTTTTTTCCAAAAAAACATATTGCAGTATTAAATCT
CTTAATGCCAATATTAATCGATATAATCAATTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016273.1\|WP_002213060.1\|1369440_1369905_-\|methylglyoxal-synthase	unknown	unknown	gnl\|CDD\|179969
NZ_CP016273.1\|WP_002213061.1\|1367394_1369380_+\|DNA-helicase-IV	unknown	unknown	gnl\|CDD\|182930
NZ_CP016273.1\|WP_002213054.1\|1371604_1371922_-\|heat-shock-protein-HspQ	unknown	unknown	gnl\|CDD\|184526
NZ_CP016273.1\|WP_002213034.1\|1382101_1382626_+\|beta-hydroxyacyl-ACP-dehydratase	unknown	unknown	gnl\|CDD\|223835
NZ_CP016273.1\|WP_002228570.1\|1388235_1388676_+\|lipocalin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372819
NZ_CP016273.1\|WP_002213032.1\|1382615_1383899_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl\|CDD\|238430
NZ_CP016273.1\|WP_002213049.1\|1373266_1373545_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|184675
NZ_CP016273.1\|WP_002213024.1\|1387360_1388149_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP016273.1\|WP_002213039.1\|1377571_1379989_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366708
NZ_CP016273.1\|WP_002213058.1\|1370083_1370764_-\|DUF2057-family-protein	unknown	unknown	gnl\|CDD\|179619
NZ_CP016273.1\|WP_002213046.1\|1373596_1373926_-\|sulfurtransferase-TusE	unknown	unknown	gnl\|CDD\|225472
NZ_CP016273.1\|WP_002213038.1\|1380142_1380889_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180440
NZ_CP016273.1\|WP_002213017.1\|1388713_1388962_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NZ_CP016273.1\|WP_002213052.1\|1371982_1373173_-\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	unknown	unknown	gnl\|CDD\|185082
NZ_CP016273.1\|WP_002213026.1\|1385884_1386604_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|223955
NZ_CP016273.1\|WP_002213036.1\|1381619_1381838_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016273.1\|WP_002213028.1\|1384653_1385892_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NZ_CP016273.1\|WP_002213025.1\|1386605_1387358_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|235936
NZ_CP016273.1\|WP_002213056.1\|1371079_1371496_+\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|224745
NZ_CP016273.1\|WP_002213030.1\|1383900_1384638_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187594

Protein	Function_ID	Function_description	E-value
NZ_CP016273.1\|WP_002213060.1\|1369440_1369905_-\|methylglyoxal-synthase	gnl\|CDD\|179969	PRK05234, mgsA, methylglyoxal synthase; Validated.	2.55286e-93
NZ_CP016273.1\|WP_002213061.1\|1367394_1369380_+\|DNA-helicase-IV	gnl\|CDD\|182930	PRK11054, helD, DNA helicase IV; Provisional.	0
NZ_CP016273.1\|WP_002213054.1\|1371604_1371922_-\|heat-shock-protein-HspQ	gnl\|CDD\|184526	PRK14129, PRK14129, heat shock protein HspQ; Provisional.	3.64231e-72
NZ_CP016273.1\|WP_002213034.1\|1382101_1382626_+\|beta-hydroxyacyl-ACP-dehydratase	gnl\|CDD\|223835	COG0764, FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases [Lipid metabolism].	1.09929e-42
NZ_CP016273.1\|WP_002228570.1\|1388235_1388676_+\|lipocalin-like-domain-containing-protein	gnl\|CDD\|372819	pfam13924, Lipocalin_5, Lipocalin-like domain. This family includes domains distantly related to lipocalins. However, they do contain the important GXW motif in the first strand. The protein in this family include aln5, which is involved in biosynthesis of alnumycin. The family also includes the ZFK protein from Trypanosoma brucei which is a protein kinase. This domain is at the C-terminus of that protein. The domain is also found as the C-terminal domain in StiJ a protein involved in producing stigmatellin. This domain has been assumed to catalyze a final cyclisation reaction.	5.67247e-46
NZ_CP016273.1\|WP_002213032.1\|1382615_1383899_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl\|CDD\|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	2.93328e-136
NZ_CP016273.1\|WP_002213049.1\|1373266_1373545_+\|acylphosphatase	gnl\|CDD\|184675	PRK14426, PRK14426, acylphosphatase; Provisional.	1.02172e-54
NZ_CP016273.1\|WP_002213024.1\|1387360_1388149_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.49415e-40
NZ_CP016273.1\|WP_002213039.1\|1377571_1379989_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	1.41205e-31
NZ_CP016273.1\|WP_002213058.1\|1370083_1370764_-\|DUF2057-family-protein	gnl\|CDD\|179619	PRK03641, PRK03641, DUF2057 family protein.	4.09411e-122
NZ_CP016273.1\|WP_002213046.1\|1373596_1373926_-\|sulfurtransferase-TusE	gnl\|CDD\|225472	COG2920, DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism].	2.4785e-71
NZ_CP016273.1\|WP_002213038.1\|1380142_1380889_-\|SDR-family-oxidoreductase	gnl\|CDD\|180440	PRK06172, PRK06172, SDR family oxidoreductase.	1.01866e-70
NZ_CP016273.1\|WP_002213017.1\|1388713_1388962_+\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	4.77778e-09
NZ_CP016273.1\|WP_002213052.1\|1371982_1373173_-\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	gnl\|CDD\|185082	PRK15128, PRK15128, 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI.	0
NZ_CP016273.1\|WP_002213026.1\|1385884_1386604_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	1.17502e-35
NZ_CP016273.1\|WP_002213028.1\|1384653_1385892_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	1.57028e-141
NZ_CP016273.1\|WP_002213025.1\|1386605_1387358_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	2.57932e-133
NZ_CP016273.1\|WP_002213056.1\|1371079_1371496_+\|CoA-binding-protein	gnl\|CDD\|224745	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only].	1.53332e-71
NZ_CP016273.1\|WP_002213030.1\|1383900_1384638_+\|SDR-family-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.26541e-68

>NZ_CP016273.1|WP_002213038.1|1380142_1380889_-|SDR-family-oxidoreductase
MKKTILITGALSGIGNTATKLFSEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDVAVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAGLVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKKAFIEMMPNKRFTTQEEVAHTIVFLAEDNVTAITGQTITIDGGYTAQ
>NZ_CP016273.1|WP_002213039.1|1377571_1379989_-|GNAT-family-N-acetyltransferase
MTTTLDIINSAKDLDPAEYRAFFLQSKAPLFYDLRFLIAAEQSPLLNVSKIFYLLARDEGRLIALVPLYLQEFRSADPLGLLISSAKLSIESEERGLFSHIIHCTDTTIPTLSHDPSLYARIFDAITAIAQAELARYFCFLNVQDGVLLREAQRNGLNINYMVDKFSIELDAFPDFDSFAQALPKYRRYEMVRQLRIFNRSDAKVRILAPPFDNEIEKLARLYYLTTQRLGTPYYWPESQLAVFCRLCGDLVRLIVVEQNGQIVSGFICFEEDGALHFWSAGMDDESSDFSPYTLGVSAVYRYAFEKGINLIECGRLNSHIKTRLGFKPKRLYSIVSQDLGIPAATQTSLSQLKLASQLDGEVRLASHPAFDEWYLTSVWNGRGPTRRPAGIVRAATEADVIRTIVFAKERGMEVSVRGSGHNYVGCFLRVDTLMLDISGLKGLDIDSRHKRAIVESGVSSGQLCHALAAKGLAFPTGHVKEVGISGFLLGGGLGINCSQWGGMSVFNVQALDIVTADGHLRHVSETQEPDLFWAARGAGPCSFFVVTRFYLSCYSLPRVITNSLYTLPFTYLHDLLARLEDASPPTNLQVMVSVSPPTSGDTPAVLLNILAFTDSPQEAQALCESFETRLELPLTALAINQPSNFETIYEQFSSMVVSKRFYADNILTDNTQELVSILSRYLSDAPSRGALTTIFWRGVTTYPQAAFSAHGKFFVSTYAQWDDAKDDSVNKYWLKRMYDELQEIARSRYINEYDLETRAGETSKCFAAENWERLQRLRLEYDPDGVFVDVQQLEEHGDQPGANN
>NZ_CP016273.1|WP_002213046.1|1373596_1373926_-|sulfurtransferase-TusE
MLEFEGRIIDTDAQGYLKNSTDWSEALAPVLAEQEGITLTEPHWEVVRFVRAFYQEFNTSPAIRMLVKAMAQKYGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
>NZ_CP016273.1|WP_002213049.1|1373266_1373545_+|acylphosphatase
MSKIYIVAYVYGVVQGVGFRYSTQRQAQQLGVTGYAKNCDDGSVEVVASGNPQAVERLMEWIRQGGPRGARVDRLLTEPYPPTPFETFSIRY
>NZ_CP016273.1|WP_002213052.1|1371982_1373173_-|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI
MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRVM
>NZ_CP016273.1|WP_002213054.1|1371604_1371922_-|heat-shock-protein-HspQ
MIASKFGIGQQVRHSLHGYLGVVIDIDPEYSLAPPEPDEVANNKTLRSSPWYHVVIEDDDGQPVHTYLAEAQLTYEDVDAHPEQPSLDELAASIRHQLQAPHLRN
>NZ_CP016273.1|WP_002213056.1|1371079_1371496_+|CoA-binding-protein
MHDKDIADILKKVKTIALVGASDIPSRPSYRVMAYLLQQGYQVTPVNPKLAGELLLGQLVYAELADIPHAIDMVDVFRNSDAAYCIAQDAIAIGAKVLWLQIGVINEQAAILATDAGLQVVMDRCPKIELPRLGLEKG
>NZ_CP016273.1|WP_002213058.1|1370083_1370764_-|DUF2057-family-protein
MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
>NZ_CP016273.1|WP_002213060.1|1369440_1369905_-|methylglyoxal-synthase
MELTTRTIAARKHIALVSHDHCKKSLLAWVMENRDLLAQHELYATGTTGNLVQKATGIDVHCLLSGPMGGDQEVGALISEKKIDILIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIGSTLFSSEVTIAIPDYDRYMQQRLDLK
>NZ_CP016273.1|WP_002213061.1|1367394_1369380_+|DNA-helicase-IV
MELKATSFGKHLSQHPYNRVRLLNAGIEVCGDKHQYLIPFNQLVSIQCKRGIVWGELEFELPQQKVVRLHGTEWQETQHFYHYLLGVWQQWSEEMSQVCAEVLHKQVESIKRIEQQDKWFKRSELGQIQVMIREAFSALPMPVERLAAFESCRADYECCLRWLQQGRHSVERCNQQWTARMLEEYQDFFQNVETSPLNASQSRAVVNGEDSVLVLAGAGSGKTSVLVARAGWLLRRNEALPEQILLLAFGRQAADEMNSRIKQRLGVDSIQAKTFHALALHIIQQGSRKTPVISKLESDSQARRALLIQHWQQQCSEKKAQDKRLAARLASRLERWVGLMRMYGGSQAEMIEQANDEVRDLFQKRIRLMAPLLKAWKTALKDEGAVDFSGLIHQAVNLLEKGRFVSPWKHVLVDEFQDISPQRAMLLAALRKQNKQTCLFAVGDDWQAIYRFSGAELSLTTAFSEHFGEGAECALDTTYRFNDRIGDIANRFIQQNPYQLKKPLNSLSKGNKKSVMILPDEQLEALLDKLSGFVKDGERILILARYHHLRPEVLQKAATRWPKLTIDFMTIHASKGQQADYVIIVGLHEGNDGFPAAARESVLEDVLLPPPEDFPDAEERRLLYVAITRAKHQVWLLQDTARPSIFVSQLSELGALVQRKP
>NZ_CP016273.1|WP_002213036.1|1381619_1381838_+|hypothetical-protein
MYLLQQIELCPDQILHAWKISQNPQVSEVFEIEVVSSEEDAEEAVLFWKAYFSSLGETVIDGRHVGDTFSRF
>NZ_CP016273.1|WP_002213034.1|1382101_1382626_+|beta-hydroxyacyl-ACP-dehydratase
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
>NZ_CP016273.1|WP_002213032.1|1382615_1383899_+|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MSSDRIVITGVAINTPIGDTLDLVGNNLLSGKSAIGYWRNFDTSNIYSKIGGQIPEYDIEGKLHAFSNRIPDIVLSRAEKVFKQTTKGVQLSVLMAMEAWLDAGLFEHIIDPFDCGIICGGHNLSDKYLLDQQKIFSDEPEFIDAFSGLNSLDTDHSSSVAQVLNTKGFAYLVGGTCATGNIAIQTAINAIKVDKKQVVAVVCPMASFHPMMLHSLTILEAICYSQYQDTPTKASRPYDINRSGFLPSEGGAVLIFEQAEHAKNRGAKIYAELLGASVNSDANHLGDPSHEGQVRVIQDVLKKCNISPEQVDYVSAHATSTKLGDIVELKSIKRVFGSHAEKLIINAPKSLLGHTMWASGVVEAAIAIWQMRQGEFHQSHNIETLDPAVELNVCASGNVKKEVNIFLNNSFGMGGINSASLFSRYHG
>NZ_CP016273.1|WP_002213030.1|1383900_1384638_+|SDR-family-oxidoreductase
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSNIDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVGLTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEAILFLVAKESSYVNGAVFNVTGGIDWVY
>NZ_CP016273.1|WP_002213028.1|1384653_1385892_+|hydroxymethylglutaryl-CoA-synthase-family-protein
MNSIGIEKISIYPSSLALKLSELAQARGGDNKYIQESLMVIKRSLVPQWEDAVTLAVNSAKDMLNDQDRSDIGLFIIATESGLDQEKAISTWAHRYLGLPATCRVFELKSACHAGAAALKMAESWISSGLNRGKKVLLINVDISNNMICHGKMEYSLGAGAIALLISDNPVFAVIETGKSGIHTHEVTDVIRPLPWKEVAFDVEASLFSYMDGLENAFEEYCHQTPEARESTYFNYNLYHVPFPGISKEAHKVLLELQGLFGKEALATSFKQKVMPSLYYAQKIGATYCGSIFLSLFSLMVKAPEIKSGDRIGVYSYGSGSCAEYFSMQVGDQAVEIAQQQGAALDILLTQRKILDVAAYEQLENARSAQMQGKDYRLDGDNLQDWYTHHYSGSGLLILERIDNHLRRYRYA
>NZ_CP016273.1|WP_002213026.1|1385884_1386604_+|enoyl-CoA-hydratase/isomerase-family-protein
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD
>NZ_CP016273.1|WP_002213025.1|1386605_1387358_+|enoyl-CoA-hydratase/isomerase-family-protein
MKKIYLRKSDEGIAFMHINDPVNKNAIDDEFCLQLHGIVDTIKQDKTIKVLILVGLPDIFCTGGTEAFLQSLITHYKTNIEHEYANHLKHFLNIPIPVIAAMEGSATGGGLVLGLYADILVAAEESRYGMSFMNMGFTPGMGSTAMSKEAFGYYTGFEMMVTGNYIRGSELKGKCCFNYILPRAMVMEKAIELATSIAEKPRHSLELLKKYMSIDRRKMLEETSTIEAFMHHIAFNQSNIEQQIQDNYTG
>NZ_CP016273.1|WP_002213024.1|1387360_1388149_+|SDR-family-oxidoreductase
MLNNLSEMTVLVTGGTKGIGRATVESFVKAGAKVYGTYFWGDNLDELENHFSQYLNRPVFLQADISDEEITTQLIEKIAQENKKIDILILNAAFAPQFKDTYKFRGLLDSIEHNSWPLITYIDCIKQHFGQYPGYVVAITSEGHRSCHITGYDYVAASKAVLETLTKYIGARENIIINCISPGVVDTEAFELVFGKKAQAFIRKFDPDFIVSPEAVGNVSVALCSGLMDAVRGQVITVDNGRMFTDNFTKWIDMIETNFIEK
>NZ_CP016273.1|WP_002228570.1|1388235_1388676_+|lipocalin-like-domain-containing-protein
MSNPNRNLFLGRWKLESCIGNSGGIHIYPIGREPFGMLIYTEQYMMVFISSVERTQFSTEDIRAIPSEQIVADFPKFETYCGHYIVNHDEKIVTHFIDNSKIPNQIGTQFRRYFSFEHEKLVLKSIDSLLLNDESWLFELVWNKQE
>NZ_CP016273.1|WP_002213017.1|1388713_1388962_+|acyl-carrier-protein
MDRDHIASIVKKHIVNSIDGAKEHEIDLQKSMADYGASSLDIVSVVSGVMRELKIKIPRTELKNIKSINGLIDLFVTSSSES

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Crispr_ID: NZ_CP016273_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016273_3

2411636-2412144

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	PILER-CR

8 spacers

cas1,cas3f,cas8f,cas5f,cas7f,cas6f

The CRISPR arrays of NZ_CP016273_3

>merge|NZ_CP016273|3|2411636-2412144|CRISPRCasFinder,CRT,PILER-CR
TTTGATTATTGCCTGTGCGGCAGTGAACTCAGGGGACTGGCGAACAATGTCTTTCATGATTTTCTAAGCTGCCTGTGCGGCAGTGAACGAAAAGGTAAGATGGGCAAGCTTCTAGTAGTTTTTCTAAGCTGCCTGTGCAGCAGTGAACATTATCTGAATGGCATTTTCTTTGGCGCAGATTTTCTAAGCTGCCTGTGCGGCAGTGAACTCGCCATTCCGTGAACCTGAGCGCGTTCGCGATTTCTAAGCTGCCTGTGCGGCAGTGAACATATTCTCGAGCGATAGCAATAGCCATTCCACTTTCTAAGCTGCCTGTGCGGCAGTGAACTCGGTCAAACAAATTTAGGCGACGATTTAACATTTCTAAGCTGCCTGTGCGGCAGTGAACAAAAAGAATTTGGGATTAAAGTTACCCATCAGTTTCTAAGCTGCCTGTGCGGCAGTGAACTCAATGCCTGAATCTCTGGCGTGATAGCTGCGGTTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NZ_CP016273|3|3|2411636-2412144|CRISPRCasFinder
TTTGATTATTGCCTGTGCGGCAGTGAAC	TCAGGGGACTGGCGAACAATGTCTTTCATGAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GAAAAGGTAAGATGGGCAAGCTTCTAGTAGTT
TTTCTAAGCTGCCTGTGCAGCAGTGAAC	ATTATCTGAATGGCATTTTCTTTGGCGCAGAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCGCCATTCCGTGAACCTGAGCGCGTTCGCGA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATATTCTCGAGCGATAGCAATAGCCATTCCAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCGGTCAAACAAATTTAGGCGACGATTTAACA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	AAAAAGAATTTGGGATTAAAGTTACCCATCAG
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCAATGCCTGAATCTCTGGCGTGATAGCTGCGG
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NZ_CP016273|3|1|2411636-2412144|CRT
TTTGATTATTGCCTGTGCGGCAGTGAAC	TCAGGGGACTGGCGAACAATGTCTTTCATGAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GAAAAGGTAAGATGGGCAAGCTTCTAGTAGTT
TTTCTAAGCTGCCTGTGCAGCAGTGAAC	ATTATCTGAATGGCATTTTCTTTGGCGCAGAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCGCCATTCCGTGAACCTGAGCGCGTTCGCGA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATATTCTCGAGCGATAGCAATAGCCATTCCAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCGGTCAAACAAATTTAGGCGACGATTTAACA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	AAAAAGAATTTGGGATTAAAGTTACCCATCAG
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCAATGCCTGAATCTCTGGCGTGATAGCTGCGG
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NZ_CP016273|3|1|2411696-2412144|PILER-CR
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GAAAAGGTAAGATGGGCAAGCTTCTAGTAGTT
TTTCTAAGCTGCCTGTGCAGCAGTGAAC	ATTATCTGAATGGCATTTTCTTTGGCGCAGAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCGCCATTCCGTGAACCTGAGCGCGTTCGCGA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATATTCTCGAGCGATAGCAATAGCCATTCCAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCGGTCAAACAAATTTAGGCGACGATTTAACA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	AAAAAGAATTTGGGATTAAAGTTACCCATCAG
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TCAATGCCTGAATCTCTGGCGTGATAGCTGCGG
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016273.1\|WP_002211867.1\|2403288_2404293_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|378222
NZ_CP016273.1\|WP_002211863.1\|2399707_2401066_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP016273.1\|WP_002210199.1\|2420835_2422122_-\|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224567
NZ_CP016273.1\|WP_002210196.1\|2417824_2418880_-\|glycoside-hydrolase-family-130-protein	unknown	unknown	gnl\|CDD\|350124
NZ_CP016273.1\|WP_002210194.1\|2415621_2416737_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016273.1\|WP_002211868.1\|2404310_2405261_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09676_cas5f_CAS-I-F	gnl\|CDD\|187807
NZ_CP016273.1\|WP_002210201.1\|2423450_2424839_+\|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl\|CDD\|185312
NZ_CP016273.1\|WP_002210198.1\|2419851_2420727_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP016273.1\|WP_002211864.1\|2401112_2401616_+\|formaldehyde-activating-enzyme	unknown	unknown	gnl\|CDD\|224708
NZ_CP016273.1\|WP_002211865.1\|2401626_2402646_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381305
NZ_CP016273.1\|WP_002221142.1\|2407011_2410299_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|187804
NZ_CP016273.1\|WP_002210197.1\|2419026_2419851_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP016273.1\|WP_002210192.1\|2412481_2413726_+\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NZ_CP016273.1\|WP_002222491.1\|2405257_2406604_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	cd09675_cas8f_CAS-I-F	gnl\|CDD\|274203
NZ_CP016273.1\|WP_002213840.1\|2416859_2417798_-\|DUF1861-family-protein	unknown	unknown	gnl\|CDD\|378102
NZ_CP016273.1\|WP_002210191.1\|2410295_2411276_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
NZ_CP016273.1\|WP_002210193.1\|2414308_2415583_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016273.1\|WP_002210200.1\|2422393_2423434_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380502
NZ_CP016273.1\|WP_002216551.1\|2399374_2399584_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016273.1\|WP_002211866.1\|2402723_2403278_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09674_cas6f_CAS-I-F	gnl\|CDD\|378224

Protein	Function_ID	Function_description	E-value
NZ_CP016273.1\|WP_002211867.1\|2403288_2404293_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NZ_CP016273.1\|WP_002211863.1\|2399707_2401066_+\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.50877e-50
NZ_CP016273.1\|WP_002210199.1\|2420835_2422122_-\|carbohydrate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	2.85244e-50
NZ_CP016273.1\|WP_002210197.1\|2419026_2419851_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.72016e-69
NZ_CP016273.1\|WP_002211868.1\|2404310_2405261_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|187807	cd09676, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	1.12008e-157
NZ_CP016273.1\|WP_002210201.1\|2423450_2424839_+\|phosphomannomutase/phosphoglucomutase	gnl\|CDD\|185312	PRK15414, PRK15414, phosphomannomutase.	0
NZ_CP016273.1\|WP_002211864.1\|2401112_2401616_+\|formaldehyde-activating-enzyme	gnl\|CDD\|224708	COG1795, COG1795, Formaldehyde-activating enzyme nesessary for methanogenesis [Energy production and conversion].	1.50048e-90
NZ_CP016273.1\|WP_002211865.1\|2401626_2402646_+\|aldo/keto-reductase	gnl\|CDD\|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	6.34333e-143
NZ_CP016273.1\|WP_002221142.1\|2407011_2410299_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	0
NZ_CP016273.1\|WP_002210198.1\|2419851_2420727_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.26211e-58
NZ_CP016273.1\|WP_002210192.1\|2412481_2413726_+\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	2.65074e-32
NZ_CP016273.1\|WP_002222491.1\|2405257_2406604_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|274203	TIGR02564, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	0
NZ_CP016273.1\|WP_002213840.1\|2416859_2417798_-\|DUF1861-family-protein	gnl\|CDD\|378102	pfam08950, DUF1861, Protein of unknown function (DUF1861). This hypothetical protein, found in bacteria and in the eukaryote Leishmania, has no known function.	6.29599e-176
NZ_CP016273.1\|WP_002210191.1\|2410295_2411276_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	0
NZ_CP016273.1\|WP_002210196.1\|2417824_2418880_-\|glycoside-hydrolase-family-130-protein	gnl\|CDD\|350124	cd18612, GH130_Lin0857-like, Glycoside hydrolase family 130 such as Listeria innocua beta-1,2-mannobiose phosphorylase. This subfamily contains the glycosyl hydrolase family 130 (GH130), as classified by the carbohydrate-active enzymes database (CAZY), enzymes that are phosphorylases and hydrolases for beta-mannosides, and includes Listeria innocua beta-1,2-mannobiose phosphorylase (Lin0857). hey possess 5-bladed beta-propeller domains similar to families 32, 43, 62, 68, 117 (GH32, GH43, GH62, GH68, GH117). GH130 enzymes are involved in the bacterial utilization of mannans or N-linked glycans. Structure of Lin0857 shows beta-1,2-mannotriose bound in a U-shape, interacting with a phosphate analog at both ends. Lin0857 has a unique dimer structure connected by a loop, with a significant open-close loop displacement observed for substrate entry. A long loop, which is exclusively present in Lin0857, covers the active site to limit the pocket size.	9.75278e-165
NZ_CP016273.1\|WP_002210200.1\|2422393_2423434_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380502	cd06279, PBP1_LacI-like, ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group includes the ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.	1.56156e-83
NZ_CP016273.1\|WP_002211866.1\|2402723_2403278_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	1.71931e-94

>NZ_CP016273.1|WP_002210191.1|2410295_2411276_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MENAIHSSDLKTILHSKRSNIYYLEYCRVLVNGGRVEYVTDEGKQSLYWNIPIANTTVIMLGTGTSVTQAAMREFARAGVLVGFCGGGGTPLFAANDVEVNVSWLTAQSEYRPTEYLHDWVSFWFDDEKRLAAAVAFQRIRIAQIQQHWLSSHIQRESLFPVNHDQLLFILTRFEQNLANCLTSNDLMVQEAVLTKALYKLAANTVNYGDFTRAKRGGGIDLANRFLDHGNYLAYGLAATATWVIGLPHGLSVLHGKTRRGGLVFDVADLIKDALVLPQAFIAAMQGEEEQEFRQRCISGFQRTEALDVMIDGIKETAALCSQVPR
>NZ_CP016273.1|WP_002221142.1|2407011_2410299_-|type-I-F-CRISPR-associated-helicase-Cas3
MNILLISQCHKRALNETRRILDQFAERKGDRTWQTAITQEGLNTLRKLLRRTARRNSAVACHWIKSNNQSELLWIVGNLRRFNAEGTVPTNTTQRDILRSQDENNWHSVETIALLAGIAGLFHDFGKANVLFQQGLQGQGKTYQPYRHEWVSLRLFQAFVEQKNDIQWLTALSQINPADETTLMSNLVKDGLDDYTNPLAALPPLAKTIAWLILSHHRLPVYPSKDYHRPPKVEEIDDWLHQQLMPVWNSTNMDSGDWREKDKLDVWRFPHGTPLQSAEWCKKAQKFAKRALRQPSLVNDGHLNQRFTSHMARLVLMLADHHYSSLPATPGWQDKNYQVFANTHNKMRDANAHSKTIEMKQRLDEHNIGVGQNALLLGRSLPHIRKTLPAITRHKGFKQRSVQEKYRWQDKAFDLAVTLRERSLQQGFFGVNMASTGCGKTFANARIMYGLSDEKQGCRFSVALGLRTLTLQTGTALQQKLTLQKDDLAVLIGSQSVLQLYQLNNDKLEPRGTGSQSADKFFSEHQYVSYDGSLDDGRLSTWLSNNDRLKRLLCAPVLVCTIDHLIPATESLRGGKQIAPMLRLLTSDLVLDEPDDFDRNDLPALCRLVNWAGMLGSRVLLSSATLPPALVQALFNAYRAGRADYQQASGQPDTPVNICCAWFDEHGVAQQDIQQSKDFIQHHGDFITRRVGKLSTAEVLRRAELIPVSSASVKNGSVLDAMAAVMRDSMLRLHQAHHQTHPSEKTVSVGVVRMANIDPLVAIAQRLYAMAAPENYRIHYCVYHSQHPLAVRSAIERRLDVTLTRYQPNALWQVAEIEHALQHHPEQHHLFVVLATSVVEVGRDHDYDWALAEPSSMRSFIQLAGRVQRHRQVAPQMANMHILQKNFKALTQKDPAIPVYCKPGFETTRCRLNTHDLDKLLLPSQYKVINAISRIQERTKLEPRDNFVDLEHLSLRLILQGSAEPLKYYAALWWRKQATWSGEQQRCTPFRQSSPDEQHNLWIDDEADKPVFKRLDSDQIEWKVSDGFQDVELTLAAGNSAWIDTDCLRIYQWLAESLNKELNEVSRQFGEVRLPKKDGERWHYHPLLGVFGALD
>NZ_CP016273.1|WP_002222491.1|2405257_2406604_-|type-I-F-CRISPR-associated-protein-Csy1
MSDEGLAAFIVSYIKSREQPKLEAFDKEAEKRLAGLTQAEDIALAQQEIAQQRQELIARYEVRNWLTDAANRAGQIKLATHAPKYTHSDSKSSGILNIELQSKKKDYFSSVDLAEQASDVIGNAAVFDLVKLLQSECEGGSLIKCLEQGDNSVLKLFSNDDELVEEWTTKFKSILNNEKFTSHKLAKQFYFPVGPDQYHLLSPLFSSSLAQAMHQRIIEARFSDQSKEAKAAHKAGRWHPTVRVLYLDTAVQHIGGTKPQNISYLNSVRGGKVWLLPCGAPSWKNIQKPPIKYRSIFHDRSEFTVLARNNLWQMQLYLLGVKPLSNTMDIRAARLACCDEIIDILFNYVAEIQNLDGTNGWSDAEDCKLKRSEQLWLDPTRAMDDPVFKLEREKEDWKQEVSQDFGYWLNRWLQHDELVFGYVEQREWSSLFKQRLREFEQGSLETSS
>NZ_CP016273.1|WP_002211868.1|2404310_2405261_-|type-I-F-CRISPR-associated-protein-Csy2
MSSLIVLHQVRVENANAIAGLTYGFPAITHFLGYSHALSRKLQSSHGLTLRGCAVICHYQQVHAYLSGWDYVFSLTRNPLTKEAKTAAFNEEGRMHMTVSLVIECDGTIANGDDGANALEKHLASLCLTQRLAGGTITNIRRVKVINYPETEVATRRLLCRLLPGFALLDRSELLAEHLNRLRQTNPQAEMLDAWLDFSALKIQAIPPQSDTPVESGAPAPWGYVGKPAAGYLVPIVTGYRAISPLYAPGEVDKTRDPHTPFRFVESLYGIGEWRGLHRITDLRQLLWGYHQEGDNYLCRCALPASVDTYLLNDEE
>NZ_CP016273.1|WP_002211867.1|2403288_2404293_-|type-I-F-CRISPR-associated-protein-Csy3
MAKATIKTASVLAFERKLSNSDAMMYAGNWGQTDNWQPIIIKEKAVRGTISNRLKNALASDPAKLDAEIQKANLQRVDVAALPFDTDTLKMSFTLRVLGNLATPSVCNDQEYQAELASVINGYISEQSFSVLAARYAENLANGRFLWRNRVGAEDIKVCITSQTKSYQFDSNEFSLRQFSQPSKELTALAQEIEQGLAGNGFAFFTVDAFVRLGNGQEVFPSQELVLDSNSKKSKVLYQIDGIAALHSQKVGNALRTIDDWYPDATELALGPIAVEPYGSVTSRGKAYRQPKQKMDFYTLLDNWVTKGTVPAVEQQHYVMATLIRGGVFGEKGE
>NZ_CP016273.1|WP_002211866.1|2402723_2403278_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MDHYLDIRVLPDPEFSAQTLLEALFAKLHRALVATIPGRVGVSFPTAGKTLGSQLRLHGSRGDLLELQSAGWLKGLQDYCECSEILPVPADVKHRTIRRVQVKSSAQRLRRRSVSKGWLTEEQARLRIPDSHDKRCDLPFLRLKSRSSEQYFLLFIEQGTLQASATTGEFSAYGLSVNATIPWF
>NZ_CP016273.1|WP_002211865.1|2401626_2402646_+|aldo/keto-reductase
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYSAGVGEEVVGRIVKNLMSRDELVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDYIDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMFTWQLSKILWCCERNGFAKPINMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYADVTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLNAEEHFELERNYTPCDVINDYTAGQRIAREARPPSGIFAP
>NZ_CP016273.1|WP_002211864.1|2401112_2401616_+|formaldehyde-activating-enzyme
MQMYIGEGFAGNGVNAAHINIMIGPRDGVVGQAFAASLASPSQGHYPFIVVIKPNVAAKPMTLYVNKAEIRSELHGRATWGASQAAVAKAVAEALLANLFPPEAEDDWCIITANWVNIDCDDIDEVYRNNYRACTTALHAAMAKTPKRDQLTHALTQLSNPFFTPKA
>NZ_CP016273.1|WP_002211863.1|2399707_2401066_+|MFS-transporter
MQTLPSEKIRMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEGLLGSAALIGLFLGSLILGWISDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIVGIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYVSASFVGHYLSMVSPEAWRWLLSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRFLSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGALVGIVLTAFCSRRSFLISSFIFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVNYGMPVTTTLLAFVLIIGAIVSIAWAPETKGLTLVDASQSATTPRPPSSIIPN
>NZ_CP016273.1|WP_002216551.1|2399374_2399584_-|hypothetical-protein
MVIGDLLTETDRLFQKRTAAMDDLFSSPGPVRLILFVMAMCQPKYKAASAFYAYPSEKKVRDPPLNSYK
>NZ_CP016273.1|WP_002210192.1|2412481_2413726_+|mechanosensitive-ion-channel-family-protein
MQQRISQWLERLGMEFSDVMSLTMVIGLILLISVMIHLVLHRVVLAALQRRGQQSQRIWQQAITKHKLFQRVALLLQGIIINLQAVLWLQNGSQTQAVIVTAAQVWIMAFALLALFSLLDTLLALLRQSSVAHQLPLRGICQGLKLVAAIFIGIMIVSLLMGRSPLLLLSGLGAMTAVLMLVFKDPILGLVAGIQLSANDMLKIGDWLEMPKYGADGAVTDIGLTTVKVRNWDNTVTTIPTYALISDSFKNWRSMSESGGRRIKRSINIDTTSVHFLSEQEQQRLTLNPLLQHYLSEKSQELNQYNQQIALDLSSPLNGRRLTNIGTLRAYLVAYLRAHLGIHQSMTLMVRQLAPTPEGLPLEVYAFTNTTIWAEYEGIQADIFDHIFAVVSEFDLRIHQTPSGNDMRSMLAKV
>NZ_CP016273.1|WP_002210193.1|2414308_2415583_-|hypothetical-protein
MKLLNTLVCIIGLTSFSSSAKLVNAEHLDALYQKVTVANKTELGLIHIYSEFPDYRWVKDPIEGVSAIDDVARAAIFYQRQYQATGSAADLEKVKSLVEFILYQRADNGYFYNFIYPDHSINKEYKTSVAEPNWWTWRALWALTQVYPTLVKTDNALAQRTRETIFATIDVIYKDFNFKQTRGEKEGVAVPEWLPHTAGDQASVLLMALSDAQALEAKPEIEKMMRSLAAGIMLMQVKDTSSPVNGAFLSWQNLWHGYGNSQAYALLVAGNRLGDRDMIKAAFNELDHFHPWLISNGLLNEFTVRQQGEKVTLIEQKKFSQIAYIIRPMVFANIKAWEISRDAVYLERAVDLSLWFFKNNPAQAQMYYPVTGIAFDGIDSATTVNKNSGAESTIEALLTLQLIESIPDAKRMLESALEKRNIKQ
>NZ_CP016273.1|WP_002210194.1|2415621_2416737_-|hypothetical-protein
MKHKKYLPLFLMAGICSVAQADNSPDVVSANNMDNRTFFAGDKIRIVKDGGETIEAVVELSDDNIGIVRIPKDEKAYFHGNWLAEYKIEHFRNEGRSTNSRPVHEIVFADGRVNFGDTGWNTGFLLKQVRFTSDSRNESNHKVDFRMVEMEIRPAWSKSIDKHWFMFEGIYLGKTGYEKNRTTGGDNNIGGDGYGFRPYYRYQVSDRLSVNTDVKMLVEDKDARGADNGRFQFYEALVNVNYRVADNVHVGIEVFRKEGQDFNHNGTKTANVLEQELRPWVAWNMGKNNFLFKMEPQLRRIGGQDGYRETSKAQKYIFNYSYPIADRVYLVAEYFYRVEHDKKFWDRGVRDNKSYSDTTTHFGKLGINYIF
>NZ_CP016273.1|WP_002213840.1|2416859_2417798_-|DUF1861-family-protein
MMRHAPPASVAQLFADYQKRTAHNTFSTGRLEFTGVGDKDVYNITAPFTSAGQVVIAGRVEARDSEHSTIVFFSEQQGQWAPVENAPTFQLQDPFFTRIEDELILGGVEINPHPDNPRQLIWHTVFFRGRDIHSLTRFASGPPGMKDIRLCHIQQGRIGVFTRPQGKIGGRGTIGYVEINNLEALTPETITSAELFEQQFNSEEWGGVNETHLLCDGTIGLLSHIACFDQHGRRHYYPGVFIFNPDTKNYTPIKIIAARDNFLPGATKRPDLVDVIFPGGLIVLPNNGWRLYVGASDAEAHWIDIEDPFSGF
>NZ_CP016273.1|WP_002210196.1|2417824_2418880_-|glycoside-hydrolase-family-130-protein
MMRYSGNPLITPQDITPSHPGFKVECAFNAGITKLGDETIMLIRIAESVIPESEGITVVPLLMEISGHWQVTTRVFKHDDPAYDFSDPRLISDIADPSTVYLTSLSHLRVARSHDGVTFVVDDQPFIFPANGDEAFGCEDARITQIDGAYYINYSAVSAKGICTALAVTQDFTDVKRLGLIFCPDNRDACLFPEKINGKYMTLHRPAPKHFGKPEIWLASSLDLLHWGDHRHLLGTSQDPWDALKLGGGAQMLKTEKGWLQIYHGVDATQRYSLGALLLDLEQPTKILAKSPVPLLQPQAPYELHGFFGNVVFTCGALIENDSLRVYYGAADECMCLAEMPLAQLWQHLSV
>NZ_CP016273.1|WP_002210197.1|2419026_2419851_-|carbohydrate-ABC-transporter-permease
MKKNINSLIIHLVMFSLALSWLYPYIWMVLSSFKQSADIYTTGLFGSAYSLDNYRFLFENSGRVEKPFLKTLFNSLFISTVVTVAVTLSSMFIGFALAKMQFKGQSLFRNLLFLQMVFPASMFIIPQFVLVRELGLLNTYSAMIVPFLMSSWGIFMISQSFQGTPNDYIHAAKIDNASLWQIMIYLMMPLNKAIIAIVALFTFVGTWDNFLWPLIVIQDESKMPLSVLLATFSKSYGVYVGPVIAGAVIQTIPIVVLFILFRKYFMQGMSLSLK
>NZ_CP016273.1|WP_002210198.1|2419851_2420727_-|sugar-ABC-transporter-permease
MTFLKLKDKQVGSVLAASYLGYTSIFWFYPFIWLAVLSLTEWRFVGIPTFNGLNNFILVMQDPLFWKSMLNVMRFLMYYLPIVFISSFLFAFGLQKLKHGRTFVALSFLLANVSSGVAYSIVFSKIFSQNGPLNTFLYDWFGFTLPWLTSPDFAMLSIALVVTWKFVGYYGLILFSGLNSIPKEIYSAAELDNTRTIKRLFHITLPMINPQLIMVLVLAITVSFAIFTEPYLITGGGPLNSTTTPMIVMYETAFMKMQPSWAATMSIFIALISFGIILGVRKLLERKVEIV
>NZ_CP016273.1|WP_002210199.1|2420835_2422122_-|carbohydrate-ABC-transporter-substrate-binding-protein
MLEKMKNTLISLAIASSCVVFTGCDNDTASAKNEKQDITLWIAPNNVQEAFWSEVVGEWNKQPDKKKVVFSTIPAAGSSEEAIMNAIASDRAPDISENIFTGFGSQLADLGQVVDLSTLDGYENLISTRQMTDIMDNWRYNGKNYILPIYMNPVLFWWRGDLLKEQGFSEVPKTYDEVYALSEKYTIPDKRYAIQATSGRNWWDRWFDFIALYYAQSDGKPYIANQQASYDNQAGRDVLDFMHTLFSKKWTLYDFGQDDPLVTGKVLGAVRGPWDISRYQQQYPEILKHIKMGPMLVKEQQDKPHTFADGKGLVLFSHSKVKPEAWEFIQWVFSQPKFDKRWMELTGMPPARADLLTNPFFAEYYQEHPYAAAYAEYVNVAIPPVSSGETVEIQRSMTQMIEKTAFNTATPDEALQQSIKEVNAILKP
>NZ_CP016273.1|WP_002210200.1|2422393_2423434_+|LacI-family-DNA-binding-transcriptional-regulator
MTTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRFLRTGKCGTLGVIFNDNLSYVFSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMMGALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFTCVSIDDGAAMQAICHHLLAAGHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQPHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDIQDPPVGLTTIRQPTVLKGREAARALISGQLDNDISLDFELVVRDSA
>NZ_CP016273.1|WP_002210201.1|2423450_2424839_+|phosphomannomutase/phosphoglucomutase
MEKLTCFKAYDIRGKLGSELNEEIAYRIGRAYCQWLKPAKVVVGGDARATSVELKNALAKGLMDGGADVIDIGMVGTEEVYFATRFYGVDGGIQVTASHNPIDYNGMKLVKKDAQPISGDNGLYEIQRLAQDNHFAPPGVRGQLETQLVREHYVEHLLSYIDLNALLPMKIVVNAGNGAAGPTLDALEAALAKRKVPISFIKINHQPDSSFPNGIPNPMLPENQWSTRQAVCEHQADLGIAWDGDFDRCFFFDHLGNFIEGYYIVGLLAEKFLLTNNMGKATHNTDKIIHDPRLTWNTIDIVQTLNGTAIESKTGHAFIKDAMRHHDAVYGGEMSAHHYFREFGYCDSGMIPWLLVIELLSKKTTSLFSLIESRKAKFPVSGELNFTVSDPKTKIQQIKQFYADSAIHVTGIDGLSMEFEHWRFNLRSSNTEPLVRLNIETRGDVTLLEQKTAQLTQLLYPK

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Crispr_ID: NZ_CP016273_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016273_4

2537621-2537951

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

5 spacers

The CRISPR arrays of NZ_CP016273_4

>merge|NZ_CP016273|4|2537621-2537951|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAACCGGCGGTGATGGCAATTCTACGTGGGTTCGTTGTTCACTGCCGCACAGGCAGCTTAGAAACTGATACAATCATCCTATTTGTCCTATCCAGAAGTTCACTGCCGCACAGGCAGCTTAGAAAGACAAGAACCGAATCTTTCGCCGTGCCGTAAAGTTCACTGCCGCACAGGCAGCTTAGAAACCGAAATCATCAGATGTAATTAAGATTTTTGCTGTTCACTGCCGCACAGGCAGCTTAGAAAAGACTGATGCAAGATGGCGGTATGCGTACAGAGTTCACTGCCGCACAGGCAGCTTATAGA

>NZ_CP016273|4|2|2537621-2537891|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGGCGGTGATGGCAATTCTACGTGGGTTCGTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA

>NZ_CP016273|4|4|2537621-2537951|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGGCGGTGATGGCAATTCTACGTGGGTTCGTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

>NZ_CP016273|4|2|2537621-2537951|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGGCGGTGATGGCAATTCTACGTGGGTTCGTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016273.1\|WP_002210288.1\|2522071_2523274_+\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP016273.1\|WP_002214721.1\|2550744_2551803_+\|myo-inosose-2-dehydratase	unknown	unknown	gnl\|CDD\|275172
NZ_CP016273.1\|WP_002210296.1\|2537954_2538809_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP016273.1\|WP_002210297.1\|2539114_2540641_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NZ_CP016273.1\|WP_002210302.1\|2546542_2547571_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP016273.1\|WP_002214717.1\|2529391_2530270_-\|transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273954
NZ_CP016273.1\|WP_002210294.1\|2530326_2536305_-\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP016273.1\|WP_002216059.1\|2525860_2526895_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP016273.1\|WP_002209743.1\|2528149_2529358_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP016273.1\|WP_002210304.1\|2548759_2550730_+\|5-dehydro-2-deoxygluconokinase	unknown	unknown	gnl\|CDD\|378281
NZ_CP016273.1\|WP_002210306.1\|2551812_2552628_+\|5-deoxy-glucuronate-isomerase	unknown	unknown	gnl\|CDD\|226241
NZ_CP016273.1\|WP_002210300.1\|2544005_2544935_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380623
NZ_CP016273.1\|WP_002210301.1\|2544983_2546531_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP016273.1\|WP_002359655.1\|2540675_2542601_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	unknown	unknown	gnl\|CDD\|226471
NZ_CP016273.1\|WP_002210293.1\|2527873_2528128_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
NZ_CP016273.1\|WP_002214718.1\|2536711_2537260_-\|DUF1440-domain-containing-protein	unknown	unknown	gnl\|CDD\|226008
NZ_CP016273.1\|WP_002210291.1\|2527261_2527705_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP016273.1\|WP_002210303.1\|2547594_2548728_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP016273.1\|WP_002265141.1\|2523456_2525595_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|235537
NZ_CP016273.1\|WP_002210287.1\|2521194_2521650_-\|DUF412-domain-containing-protein	unknown	unknown	gnl\|CDD\|179338

Protein	Function_ID	Function_description	E-value
NZ_CP016273.1\|WP_002210288.1\|2522071_2523274_+\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP016273.1\|WP_002214721.1\|2550744_2551803_+\|myo-inosose-2-dehydratase	gnl\|CDD\|275172	TIGR04379, myo-inositol_catabolism_protein, myo-inosose-2 dehydratase. Members of this family include the enzyme myo-inosose-2 dehydratase, product of the gene iolE, as found in inositol utilization cassettes in many species. [Energy metabolism, Sugars].	4.28689e-165
NZ_CP016273.1\|WP_002210296.1\|2537954_2538809_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.17523e-68
NZ_CP016273.1\|WP_002210297.1\|2539114_2540641_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_CP016273.1\|WP_002210302.1\|2546542_2547571_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	8.15893e-97
NZ_CP016273.1\|WP_002214717.1\|2529391_2530270_-\|transglycosylase-domain-containing-protein	gnl\|CDD\|273954	TIGR02073, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	1.09445e-118
NZ_CP016273.1\|WP_002210294.1\|2530326_2536305_-\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP016273.1\|WP_002216059.1\|2525860_2526895_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.95185e-89
NZ_CP016273.1\|WP_002209743.1\|2528149_2529358_-\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.39969e-152
NZ_CP016273.1\|WP_002210304.1\|2548759_2550730_+\|5-dehydro-2-deoxygluconokinase	gnl\|CDD\|378281	pfam09863, DUF2090, Uncharacterized protein conserved in bacteria (DUF2090). This domain, found in various prokaryotic carbohydrate kinases, has no known function.	0
NZ_CP016273.1\|WP_002210306.1\|2551812_2552628_+\|5-deoxy-glucuronate-isomerase	gnl\|CDD\|226241	COG3718, IolB, Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism].	3.14642e-169
NZ_CP016273.1\|WP_002210300.1\|2544005_2544935_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380623	cd19968, PBP1_ABC_IbpA-like, periplasmic sugar-binding protein IbpA of an ABC transporter and similar proteins. The periplasmic binding protein (PBP) IbpA mediates the uptake of myo-inositol by an ABC transporter that consists of the PBP IbpA, the transmembrane permease IatP, and the ABC IatA. IbpA shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge.	4.31227e-120
NZ_CP016273.1\|WP_002210301.1\|2544983_2546531_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP016273.1\|WP_002359655.1\|2540675_2542601_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	gnl\|CDD\|226471	COG3962, COG3962, Acetolactate synthase [Amino acid transport and metabolism].	0
NZ_CP016273.1\|WP_002210293.1\|2527873_2528128_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	1.4281e-27
NZ_CP016273.1\|WP_002214718.1\|2536711_2537260_-\|DUF1440-domain-containing-protein	gnl\|CDD\|226008	COG3477, COG3477, Predicted periplasmic/secreted protein [Function unknown].	2.91652e-69
NZ_CP016273.1\|WP_002210291.1\|2527261_2527705_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	1.55185e-43
NZ_CP016273.1\|WP_002210303.1\|2547594_2548728_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.07432e-69
NZ_CP016273.1\|WP_002265141.1\|2523456_2525595_+\|phosphate-acetyltransferase	gnl\|CDD\|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
NZ_CP016273.1\|WP_002210287.1\|2521194_2521650_-\|DUF412-domain-containing-protein	gnl\|CDD\|179338	PRK01816, PRK01816, hypothetical protein; Provisional.	1.1254e-94

>NZ_CP016273.1|WP_002214718.1|2536711_2537260_-|DUF1440-domain-containing-protein
MSEKRVNLQVIAWATIIGGFVSSLVKSGTEVNMPPRVVGEISPPAANIDAWLGWLGINSHSMDYVYQGVTISGTVVLYHWLFSFVFAFVYVLLSAYWPKVRLWYSAAYGLSITVAIHGVLIPALGFRHPAYLAGETGWLWNLNGYELWSEIIGHLCWSASLEICLVAVLAFFSKPIKGIWAN
>NZ_CP016273.1|WP_002210294.1|2530326_2536305_-|alpha-2-macroglobulin-family-protein
MDLLRFLLISPFALIKGLYRLSAYLLRLVGRLLRPVVGNLNWRAPQWMTKTANGLHCAFNRSEQWVAKHPKGISAAIVLLMAAASAAFYGYHWYLNRPQPIEPAPMVYQETSIRVSAPRTVNYQAQKPEAQPLSLNFMHSAAPITAMGQVVDQGISLTPAIEGEWKWATERTLVFTPKKAWPMGANYQITIDTEKLLAPQIKLNQTELNFTTPAFAYQLEKAEYYQDPQEAQKRSTIFHVQFNAPVDVASFEKQILLGLVEGKSKSEKKLNFSVVYDEKKLNAWIHSQPLMPMDKGGSVHLSINKGVNASVAATPTTQAQNKWVSVPNLYSLAVNSINATLVESDNNNGERALIIAISDAVKDKEIKNAVKAWLLPQHNFQAKESAKTSTDFYPWDMDDIDDNLLQQSTPLALTLNEAEQEYQPIFSFKFDAPSYRTLLIEVNNSLTSVGGYKMPEKIYQIVRVPDYPKTLRFMSQGSLLSMQGDKQISVAARNMTGMKLDIKRVIPSQLQHIVSFKSSEYSSAHFNRLSDEYFTEHFQYQTALNNDNPGEINYQGVDLSRYLANNPSARRGVFLLTLSAWDPEKRDNQQHSEEDYDEDQEWVGDSRFVVITDLGIITKQSQDRSRDVFVQSIHSGLPAADAKVSVVAKNGVVLLSQITDSKGHVHFPALDAFKNERQPVMFLVEKEGDVSFLPTRATYDRNLDFSRFDIDGEETPSDPRTLSSYLFSDRGVYRPGDRFNIGLITRTANWATALDGVPLRAEIRDPRDTLMSTLPITLDSSGFNELSYTTGENSPTGEWNVYLYLVGKNNETSMLLGHTTVNVKEFEPDRLKVQLQLTPERQQGWVKPQELQANINVQNLFGTPAQERRVTSRLILRPMYPSFAPFPDYLFYENRHNSDGFETELEEQTTDLQGMATIPLDLKSYADATYQLQLLSEAFEAGGGRSVAATARVLVSPYDSLVGVKADGDLSYINRDAVRKLNIIAVDPSLNKIALPDLSLSLIEQKYISVLTKQDSGVYKYQSRLKEQLVSEQPLQISPTGTDFTLVTQQPGDFILVVKDSQGQVLNRISYTVAGNANLTRSLDRNTELKLKLNQAEYLQGEEIEIAINAPYAGSGLITIEKDKVYSWQWFHSDTTSSVQRIRIPPAMEGNGYINVQFVRDVNSDEIFMSPLSYGVMPFKISTKARQAAIELASPSVIKPGEVLPIKVTTDSPQRVVVFAVDEGILQVARYRLKDPLDYFFRKRELSVQSAQILDLILPEFSKLMALTSAPGGDAGEGLDLHLNPFKRKQDKPVAYWSGITEVNGETTFNYPIPDYFNGKIRVMAISATPDRIGKVQTSTTVRDNFILTPNVPAMVAPGDEFDVTVGVSNNLQGLKGKAVDITVRLTPPPQLEVVGEAQHSLSLAEKRETLVSFRLRARSALGDAPLVFDASYGSQSSRRTVSTSVRPAMPFRTQSVMGRMEGNKHTVTNLRQMFDNYAQRQATASHSPLVLTQGLARYLADYPYYSSEQIVSRSIPLIMQSKHPEMDSALNQNEVRDQLKNMLRILSSRQNSTGAIGLWHASPTPDPFVTPYVVQFLLEAKSAGYSLPNDILEGANNALRLLAARPYDDLYSLRLRAFAVYLLTLQGEITTNTLASVQSTLQQLYPDSWQTDLSAIYLASSYRLLKMDDEANKLLQPTWKQLGKAYSKAWWTQNYFDPLVQDATRLYLITRHFPEKVSSIPPQALENMVLALRDEHYTTYSSAMSILALESYTSQVAAQQDTPETLQIIEISKSKGIDPNVISTLNGLFVQGDFTGEAKAIQFNNYASAPAWYVVNQSGYDLQPPKDAISNGLEISRSYTDEQGKPVTQVTLGQKVNVHLKIRANAKQGQNNLAIVDLLPGGFEVVQQTAPEPEFYDNQDDQDEETGSGWQSPLMVSGSSWYPDYSDIREDRVIIYGSASTDVKEFIYQIKSTNTGRFVVPPAYGEAMYDRNVQALSVGKGHILVVPPEAK
>NZ_CP016273.1|WP_002214717.1|2529391_2530270_-|transglycosylase-domain-containing-protein
MRIPTLMATKRLLQNILMALFLLALLVIGFRLWPHPPLSQGLPLSTAYYDRHGTLLRLSLANDDRYRLWTPLEEISPLVIQGIQLHEDRGFYYHPGVNPISLLRGFWQSYVQGGRQQGGSTLTMQLARMHWHLNTRSPTGKLRQIARAIQLELSYSKHDILEAYLNYAPYGRNIESIAAASLIYFDKKPQQLTLPEALTLAVLPQSPSYRIDPTTGVLGSALTQARNRLFVRWQQTYPTDSSQMALFQLPLSLRQPEKMPYIAPHFIEQIRRQNQQLANTRDCKQYCVIACF
>NZ_CP016273.1|WP_002209743.1|2528149_2529358_-|IS256-family-transposase
MDEKKLKALAAELAKGLKTEADLNAFSRMLTKLTVETALNAELTEHLGHEKNTPKSGSNTRNGYSSKTLLCDDGEIELNTPRDRENTFEPQLIKKNQTRITQMDSQILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDAVKEQVAEWQNRQLDALYPIVYMDCIVVKVRQNGSVINKAVFLALGINTEGQKELLGMWLAENEGAKFWLSVLTELKNRGLQDILIACVDGLKGFPDAINSVYPQTHIQLCIIHMVRNSLKYVSWKDYKAVTSGLKMVYQAPTEEAALMALDKFAEAWDDKYPQISKSWRTHWENLNTFFGYPPDIRKAIYTTNAIESVNSVIRAAIKKRKVFPTDDSVRKVVYLAIKDASKKWSMPIQNWRLAMSRFIIEFGDRLSDHL
>NZ_CP016273.1|WP_002210293.1|2527873_2528128_+|PTS-sugar-transporter-subunit-IIB
MKITVVCGNGLGTSLMMEISIKSILKELAVSAEVDHVDLGSAKGTPSDIFIGTKDIAEQLVAQAVGGKIVALDNMIDKKARACP
>NZ_CP016273.1|WP_002210291.1|2527261_2527705_+|PTS-sugar-transporter-subunit-IIA
MLKTLLTSDVIQVVSQAKDWRDAIAISCQPLIDNGAVEARYVEAIYRSHEAIGPYYVVGPGIAMPHARPEDGVNRLSLALTVITEGVTFNAEGNDPVKLLIVLAATDSNSHIEAISQLAQLFDTASDVQALLNAKTPQDILSVIARY
>NZ_CP016273.1|WP_002216059.1|2525860_2526895_-|LacI-family-DNA-binding-transcriptional-regulator
MEKIRKRRNTGRVTLQEVADYAGVGSMTVSRALRTPEQVSDKLREKIEQAVEKLGYIPNRAAGALASGHSDTVAVLIPSLTDKASSRFMQALQQILNKNEFQLLLGCHEYNQRKEAEILMTLLQSHPAAVVIFGSQLADKTYQILERTNIPIVNVVGSYFKGAKITLEAAFFESAYELTRHLLERGYQHIGYLGAHRDNQLQRQQLNGWHKSMLEHYKNADQTVTTPDAASLQFGRYALTEILLRQPELDAVICSHEDIALGVLFECQRRLLKIPSGIAVACLDGSESCDQTHPTLTSMRIDYKKMGKEAGKMLIDMLNEDDAGVKSVPLSQSFNYKFEPRQST
>NZ_CP016273.1|WP_002265141.1|2523456_2525595_+|phosphate-acetyltransferase
MLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRAGNDAPDQTTTIIRANSSITAAEPLNMNYVETLLSSNQQDVLMEEIVARYHENTKDAEVVLVEGLVPTRKHQFANALNYEIAKTLNAEIVFVIALGNDSPDQLKERIELARSSFGGSKNKNITGVIINKLNAPVDEQGRTRPDLSEIFDDSTKASVANIDPSQLFANSPIPVLGCVPWSFELIATRAIDMAKHLNARIINEGDIKTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIGAILLTGGYAIDDRINNLCERAFQTGLPVFMVDTNTWQTSLSLQSFNLEVPADDHERVEKLQNYVASHISSEWIDSLTAASERPRRLSPPAFRYELTELARKAGKRIVLPEGDEPRTIKAASICAERGIATCVLLGNPEEIQRVATSQGVELGKGVEIIDPVAVREQYVPRLVELRKSKGMTEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSAQADSAAS
>NZ_CP016273.1|WP_002210288.1|2522071_2523274_+|acetate-kinase
MSSKLVLVLNCGSSSLKFAIIDATNGEEHISGLAECFHLPEARIKWKVDGGKQEAALGAGAAHSEALNFIVNTILAQKPALSAQLTAIGHRIVHGGEKFTSSVIVTEDVIQGIKDSIPFAPLHNPAHLIGIAEALKSFPNLADKNVAVFDTAFHQTMPEESYLYALPYSLYKDHGIRRYGAHGTSHFYVSQEAAKILNKPLEELNVITCHLGNGGSVTAVRNGKCVDTSMGLTPLEGLVMGTRSGDLDPAIIFHLHDAMGMSVDQINTLLTKESGLLGLTEVTSDCRYVEDNYATKADAKRAMDVFCHRLAKYIGSYTALMDGRLDAVVFTGGIGENAAMVRELTLDKLGLLGFEIDHERNMAARFGKSGTITKDSSRLALVIPTNEELVIAQDAARLTA
>NZ_CP016273.1|WP_002210287.1|2521194_2521650_-|DUF412-domain-containing-protein
MTIKPSDSVSWFQVLQRGQHYMKTWPADKRLAPVFPENRVTVVTRFGIRFMPPLAIFTLTWQIALGGQLGPAIATALFACGLPLQGLWWLGKRAITPLPPTLLQWFHEVRHKLFEAGQAVAPIEPIPTYQSLADLLKRAFKQLDKTFLDDL
>NZ_CP016273.1|WP_002210296.1|2537954_2538809_-|MurR/RpiR-family-transcriptional-regulator
MTTASNLSELQQQIRDRYDNLSKRLQQVSRYVLDNTNSVAFDTVAVIAERADVPPSTLIRFANAFDFSGFNEMKQLFRMNLVEETASYTDRARLFRAMESEAVPETPLGILQEFARSNAQALQQLAARTEPEMLQRAVELLAQADTIYVVGLRRSFSVAAYLTYALSHLECRPVQLHGLGGMLREQVNSIKARDIVVSISFSPYAEETVMVSEIAASAGARQIVITDSQISPLATFSDLCFVVKEAQVDAFRSQSATLCLVQSLVVALAYQQEAQAGAALAHRQ
>NZ_CP016273.1|WP_002210297.1|2539114_2540641_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
METVANFINGKCVFSCGNSVTSGSPRAQAIFNSATGEPIRQVMMSTAQETEQAITAAQQAFASWSRQAPLKRARVMFRFKSLLEQHLDALAQLISEEHGKVYSDAVGELTRGLEVVEFACGIPHLQKGEHSANVGTGVDNHSLMQPLGVCVGITPFNFPAMVPMWMFPIALATGNTFVLKPSEKDPSLAVRLAQLLTEAGLPDGVFNVVQGDKTAVDVLLTDPRVQAVSFVGSTPIAEYIYQTASAHGKRCQALGGAKNHCILMPDADMDMAASAIMGAAYGAAGERCMALSVVLAVGDETADNLCARLEQQISTLRVGPGLAQEPENDMGPLISAPHRAKVLGYIDSGVAQKATLRIDGRGLKVAGHEQGYFVGPTLFDHVTPAMTIYQEEIFGPVLSVVRIADYRSAVDLINRHEYGNGTAIFTRDGGTARRFCEEVQVGMVGVNVPIPVPVAFHSFGGWKRSIFGPLNVHGNDGVRFYTRMKTITARWPEAQHDQGAAFSMPTLG
>NZ_CP016273.1|WP_002359655.1|2540675_2542601_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)
MKTVRMTMAQALVRFLNQQYVAIDGQEVAFVHGVMTIFGHGNVLGIGQALEENPGHLQVHQGCNEQGMAHMAIGFAKQYRRQRIYAVSSSIGPGAANMVTAAATATANRIPLLLLPGDIYASRQPDPVLQQIEQYHDLSISTNDCFRPVSRYWDRINRPEQLMSAMLSAMRVLTDPADTGAVTLCLPQDVQGEAWDYPASFFERRVHRIERRPPDTRRLSDALSLIARKRRPLVVCGGGVRYSGAHEAFRAFVENAQLPFTETQAGKGALPSDHPLNLGGIGVTGGLAANRLAPQADLVIGIGTRLTDFTTGSKALFSHPEVAFLLLNVAEFDALKLDATALIADARVGLEALTEGLAGYRTAWQGDIIEAKAAWCDECQRLWSRTWRPDEVPEVAGHLDDSLQEYAEVLNTTLTQTRVLGLINQHIEDDAIVVGAAGSLPGDLQRLWQVKTADTYHLEYGYSCMGYEIAAAIGAKIAMPHQPVYAMVGDGSYMMLHSELHTAVQEGLKITVLLFDNAGFGCINNLQMGHGMGSFCTESRHRNHESGQLNGPLICVDFAQNAESYGCRAWRVHDEPSLLAALAASRDHPGPVLLDIKVLPKSMTHDYASWWRTGDAQIARSPAVQQAAERTQMKVKRARQY
>NZ_CP016273.1|WP_002210300.1|2544005_2544935_+|substrate-binding-domain-containing-protein
MKKLILAALIVFTSGVAFAENEQIVFSTPNLAMPFEVHMQRTAVKTAKALGVKLQVLDGQGSSPKQVADLENAITRGAQGFIVSPNDINAISSAVEEIQQAKLPVVTLDRSVESEKKVPHFGANNYKGGEAIANYVKSMFPNGAEIVLLTGQPGSSSNIERTKGIRDSLKTGGDKYRIVVDQTGNWMRSEGMRIIESVLPSLPKPPQVILSANDDMALGAIEALQSHGMKPGEIMVTGFDAVPEALARVREGWMAVTADQRPGYAVTTAMNQLVANIRDQKAITGADFLPTMITKENLDQAERVSEAGK
>NZ_CP016273.1|WP_002210301.1|2544983_2546531_+|sugar-ABC-transporter-ATP-binding-protein
MSQPLLKITDMAKSFSGVWALSNVQLTLEQGEIHALLGENGAGKSTLLKALSGAQPQTHGEIWFNGEMLALDDSPVERQNKGIITIYQEVNLLPNMTVAENMFLGREPRRRQVFVDEKAVNQEAQAILDYLQLNVSPTTAVARLSIAQQQMVEIARALTLNAKLIVMDEPSAALSDSEVESLHRVVRELKGRGVSIIYVTHRLHEVFQLCDRFTVFQDGRYTGSDEVAGTNVEKIIRLMVGRDVVFNRRPASETHHQDQPIRLSVQGLCREKPPLDPHGVALKDISFHVHAGEVLGIAGLVGAGRTEVARCLFGAGAFTSGNFEIDGVPYQPRDPMFALEQGIALVPEDRKKEGAVQGLSIRDNLTLSSLAGLLQWRFFVNTRKEDQLIETYRLALQIKMVNSEQAVRKLSGCNQQKVILARCMALNPRILIVDEPTRGIDVGTKSEVHQVLFDMAKQGVAVIVISSDLPEVLAVSDRIITLSEGRVTGEIHGDDASEERLMTMMTINHNALNAA
>NZ_CP016273.1|WP_002210302.1|2546542_2547571_+|ABC-transporter-permease
MLQPLSKPQASVKSAMRFDPITFFERFGVLIFMFLLLIFFQLQNSNFLSERNIFNILTEVSIYGIMAVGMTFVILTAGIDLSVGSILAVSAMTAAYVIKGDNFTTIDPNAWGGMSWLIGLSICLAMGTLIGFLQGLGVTRLRLPPFIVTLGGMTIWRGLTLVINDGAPIAGFDAGYRWWGRGDLLGISIPIWIFAIVAIAGYLALHKTRWGRFVYAIGGNPEAARLAGVNVKRVLVSVYVVIGCLAGLAGFILSARLGSAEAVAGISFELRVIASVVIGGTSLMGGYGRIGGTIIGSIIMGILINGLVLMNVSAYYQQIITGLIIVLAVAFDTYAKNRRGAL
>NZ_CP016273.1|WP_002210303.1|2547594_2548728_+|Gfo/Idh/MocA-family-oxidoreductase
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMVRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>NZ_CP016273.1|WP_002210304.1|2548759_2550730_+|5-dehydro-2-deoxygluconokinase
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLARVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARSLAITGTHLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAGGSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQACRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCGADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGWPQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPPLASEGWAALNKLIERRDPHCRGVVILGLDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRDNYLQLITLWRERGQK
>NZ_CP016273.1|WP_002214721.1|2550744_2551803_+|myo-inosose-2-dehydratase
MTMVDQRTAVEPKTAVDQTTEVVRKAEVNQKIGIVRKIDIVRKTETVRKTEADRHTTAVQLGINPLTWTNDDLPSLGAETSLETCLSEGKEAGFAGFELGNKFSREAGVLGPILEHHQLKLVSGWYSGRLLERSVEEEIVAVRSHLALLRELGAKVMVFAEVSGCIHGEQQTPVHLRPRFPPARWAEYGAKLTAFARYTQALGVQIAYHHHMGTVIESAQDIDNLMIHTGEEVGLLLDTGHLTFAGADPLAVAQRWIARINHVHCKDVRTSVLADVKNRKTSFLDAVLSGVFTVPGDGGVDYPPIMALLKQHGYQGWLVVEAEQDPNVAHPMTYARMGYHNLSRLAHNAGLI
>NZ_CP016273.1|WP_002210306.1|2551812_2552628_+|5-deoxy-glucuronate-isomerase
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPFERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYTNEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPRGYHPVATMAGYDSYYLNVMAGPVRKWIFSWENDHVWINHNYPIT

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Crispr_ID: NZ_CP016273_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016273_5

3100913-3101060

Orphan

Consensus_repeat	Method
CAAATAGCAAATAGCAAATAGCAAAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP016273_5

>merge|NZ_CP016273|5|3100913-3101060|CRISPRCasFinder
CAGATAACGAATAATAAATAGAAACCCGATAATATTTTTTACTTATTAAGTTAAAACTTAATTAACCAACTTAAGAGTCGCCATATCCAAATAGCAAATAGCAAATAGCAAATAGCAAATAGCAAATAGCAAATAGCAAATAGCAAAT

>NZ_CP016273|5|5|3100913-3101060|CRISPRCasFinder
CAGATAACGAATAATAAATAGAAACC	CGATAATATTTTTTACTTATTAAGTTAAAACTTAATTAACCAACTTAAGAGTCG
CCATATCCAAATAGCAAATAGCAAAT	AGCAAATAGCAAATAG
CAAATAGCAAATAGCAAATAGCAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016273.1\|WP_002208589.1\|3098704_3099448_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133055
NZ_CP016273.1\|WP_002208592.1\|3105673_3106816_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|274425
NZ_CP016273.1\|WP_002208580.1\|3087213_3088023_+\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|226258
NZ_CP016273.1\|WP_002208586.1\|3094619_3095924_-\|inosine/guanosine-kinase	unknown	unknown	gnl\|CDD\|185033
NZ_CP016273.1\|WP_002208596.1\|3111514_3112828_-\|lipopolysaccharide-biosynthesis-protein-RfbH	unknown	unknown	gnl\|CDD\|237960
NZ_CP016273.1\|WP_002208594.1\|3109336_3110620_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224153
NZ_CP016273.1\|WP_002208591.1\|3103193_3104207_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340838
NZ_CP016273.1\|WP_002208593.1\|3107919_3109263_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240533
NZ_CP016273.1\|WP_002208595.1\|3110620_3111478_-\|NAD-dependent-epimerase/dehydratase	unknown	unknown	gnl\|CDD\|366597
NZ_CP016273.1\|WP_002229992.1\|3112845_3113919_-\|CDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|187562
NZ_CP016273.1\|WP_002215988.1\|3107195_3107909_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NZ_CP016273.1\|WP_002208585.1\|3092831_3094523_+\|Kef-family-K(+)-transporter	unknown	unknown	gnl\|CDD\|182633
NZ_CP016273.1\|WP_002208598.1\|3114734_3115724_-\|CDP-6-deoxy-delta-3,4-glucoseen-reductase	unknown	unknown	gnl\|CDD\|181058
NZ_CP016273.1\|WP_002208581.1\|3088286_3088766_+\|Cys-tRNA(Pro)/Cys-tRNA(Cys)-deacylase-YbaK	unknown	unknown	gnl\|CDD\|182634
NZ_CP016273.1\|WP_002208590.1\|3099450_3100857_-\|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|273648
NZ_CP016273.1\|WP_002208583.1\|3089102_3089342_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016273.1\|WP_002208584.1\|3091382_3092597_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341031
NZ_CP016273.1\|WP_002208587.1\|3096127_3097279_-\|LPS-O-antigen-length-regulator	unknown	unknown	gnl\|CDD\|182422
NZ_CP016273.1\|WP_002208597.1\|3113923_3114697_-\|glucose-1-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|131672
NZ_CP016273.1\|WP_002208588.1\|3097326_3098700_-\|phosphomannomutase-CpsG	unknown	unknown	gnl\|CDD\|185312

Protein	Function_ID	Function_description	E-value
NZ_CP016273.1\|WP_002208589.1\|3098704_3099448_-\|glycosyltransferase	gnl\|CDD\|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	7.27861e-86
NZ_CP016273.1\|WP_002208592.1\|3105673_3106816_-\|glycosyltransferase	gnl\|CDD\|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	2.68475e-06
NZ_CP016273.1\|WP_002208580.1\|3087213_3088023_+\|TraB/GumN-family-protein	gnl\|CDD\|226258	COG3735, COG3735, Uncharacterized protein conserved in bacteria [Function unknown].	4.11048e-109
NZ_CP016273.1\|WP_002208586.1\|3094619_3095924_-\|inosine/guanosine-kinase	gnl\|CDD\|185033	PRK15074, PRK15074, inosine/guanosine kinase; Provisional.	0
NZ_CP016273.1\|WP_002208596.1\|3111514_3112828_-\|lipopolysaccharide-biosynthesis-protein-RfbH	gnl\|CDD\|237960	PRK15407, PRK15407, lipopolysaccharide biosynthesis protein RfbH; Provisional.	0
NZ_CP016273.1\|WP_002208594.1\|3109336_3110620_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224153	COG1232, HemY, Protoporphyrinogen oxidase [Coenzyme metabolism].	6.98589e-109
NZ_CP016273.1\|WP_002208591.1\|3103193_3104207_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340838	cd03809, GT4_MtfB-like, glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.	9.33052e-75
NZ_CP016273.1\|WP_002208593.1\|3107919_3109263_-\|hypothetical-protein	gnl\|CDD\|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	0.00163004
NZ_CP016273.1\|WP_002208595.1\|3110620_3111478_-\|NAD-dependent-epimerase/dehydratase	gnl\|CDD\|366597	pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilize NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.	1.2475e-38
NZ_CP016273.1\|WP_002229992.1\|3112845_3113919_-\|CDP-glucose-4,6-dehydratase	gnl\|CDD\|187562	cd05252, CDP_GD_SDR_e, CDP-D-glucose 4,6-dehydratase, extended (e) SDRs. This subgroup contains CDP-D-glucose 4,6-dehydratase, an extended SDR, which catalyzes the conversion of CDP-D-glucose to CDP-4-keto-6-deoxy-D-glucose. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NZ_CP016273.1\|WP_002215988.1\|3107195_3107909_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	3.59337e-10
NZ_CP016273.1\|WP_002208585.1\|3092831_3094523_+\|Kef-family-K(+)-transporter	gnl\|CDD\|182633	PRK10669, PRK10669, putative cation:proton antiport protein; Provisional.	0
NZ_CP016273.1\|WP_002208598.1\|3114734_3115724_-\|CDP-6-deoxy-delta-3,4-glucoseen-reductase	gnl\|CDD\|181058	PRK07609, PRK07609, CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated.	0
NZ_CP016273.1\|WP_002208581.1\|3088286_3088766_+\|Cys-tRNA(Pro)/Cys-tRNA(Cys)-deacylase-YbaK	gnl\|CDD\|182634	PRK10670, PRK10670, Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK.	1.6143e-109
NZ_CP016273.1\|WP_002208590.1\|3099450_3100857_-\|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl\|CDD\|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP016273.1\|WP_002208584.1\|3091382_3092597_+\|MFS-transporter	gnl\|CDD\|341031	cd17478, MFS_FsR, Fosmidomycin resistance protein of the Major Facilitator Superfamily of transporters. Fosmidomycin resistance protein (FsR) confers resistance against fosmidomycin. It shows sequence similarity with the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. This FsR family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.0568e-112
NZ_CP016273.1\|WP_002208587.1\|3096127_3097279_-\|LPS-O-antigen-length-regulator	gnl\|CDD\|182422	PRK10381, PRK10381, LPS O-antigen length regulator; Provisional.	0
NZ_CP016273.1\|WP_002208597.1\|3113923_3114697_-\|glucose-1-phosphate-cytidylyltransferase	gnl\|CDD\|131672	TIGR02623, Glucose-1-phosphate_cytidylyltransferase, glucose-1-phosphate cytidylyltransferase. Members of this family are the enzyme glucose-1-phosphate cytidylyltransferase, also called CDP-glucose pyrophosphorylase, the product of the rfbF gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.82219e-180
NZ_CP016273.1\|WP_002208588.1\|3097326_3098700_-\|phosphomannomutase-CpsG	gnl\|CDD\|185312	PRK15414, PRK15414, phosphomannomutase.	0

>NZ_CP016273.1|WP_002208590.1|3099450_3100857_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MLLPVIMAGGAGSRLWPLSRALYPKQFLALTSDLTMLQETLLRLDGLPHLAPLVICNEEHRFIIAEQLRQKNLVHSGIVLEPVGRNTAPAIALAALRATMSGDDPLLLVLAADHVIQDKLAFIRAVQRAEPLAEAGKLVTFGIVPKSPETGYGYIRQGKQVVDGAYQVAAFVEKPDLITAERYLASGDYYWNSGMFVFKASRYLQELDLHRPDILAACKQAIAGQHTDLDFIRLNEEAFSSCPDESIDYAVMEKTSDAVVVPLDAQWNDVGCWSALWEINTKDDHGNVIRGDVLIEDTNNSYVYSQNRLIATVGINDLVIVETKDAILVAHKDKVQNVKGIVGQLKLESRCEYLQHREVYRPWGSHDAIAEGVRYHVQHVTVKPGQRIATQIHYHRAEHWIVVSGIAKVHYGKETYLVNENESTYIPVGIAHSIENPGQIPLEIIEVHTGNYISEDDVERIDDLGVGY
>NZ_CP016273.1|WP_002208589.1|3098704_3099448_-|glycosyltransferase
MKISIITATYNSERTISDTLSSLEKQTYLDVEYIIVDGASKDNTLTVISQNSTRVTKIISESDQGIYDALNKGIDLATGDIIGFLHSDDLLAYPGALSDIVETFEKQQCDAVYGDLQYVAKNDLNKVIRCWKSGFFNHEKMKYGWMPPHPTFYMKRDLYIRFGGFDLSYKISADYDSLTRYIINYKIKIAYLPKVIIKMRVGGISNRSLGSMLLKSKEDIQIMKLRGLFWPMSFLCKNLSKLPQFLK
>NZ_CP016273.1|WP_002208588.1|3097326_3098700_-|phosphomannomutase-CpsG
MPKLTCFKAYDIRGRLGDELNEDIAYRIGRAYGEFAKPKKVVVGGDVRLTSESLKLALSQGLQDAGTDVLDIGLSGTEEIYFSTFHLGVDGGIEVTASHNPIDYNGMKLVREGSRPISGDTGLRDIQYLAEQNEFPPVDSEKRGGYKKISIINDYVEHLINYINPSLFKPLKLVVNTGNGAAGHVIDALEKRFSELKIPITLIKIHHEPDGTFPNGIPNPLLPECRQDTTDAVLMHDADMGIAFDGDFDRCFFFNNKGEFIEGYYIVGLLAEAFLQKNAGAKIIHDPRLSWNTIDIVNSSGGTPIMSKTGHAFIKERMREEDAVYGGEMSAHHYFRDFAYCDSGMIPWLLIAELLCVKEKSLEQLVEERMRIYPASGEINSKLTDPTSAIARVRAEYEVKAIAIDETDGISMEFDGWRFNLRSSNTEPVVRLNVESHYNKTLMHHKTAEILSLLRKE
>NZ_CP016273.1|WP_002208587.1|3096127_3097279_-|LPS-O-antigen-length-regulator
MSNKQARSNLDSPIPNNYDFSNVSSSRNEIDLFEIFSVVFKSKFKIILITLFFLISGLVVSYILPQKWTSTAIIALPGDEQVQVLDELITNLTVLDIKVDVSANYLLSTFKQNFDSQDLREQYLVNTNYFKRLMKNNPEDGLDKRALIERIVNENISSVNPLKDKTEGENEYRYYKLSYSASTPTDARDLLQGSINYVNTIVNADVFRKIQRAVDLAKGIGTDKYSMELLKARNNQKVKIERLRYASSIADAAGVKKPVYSNGSAISDDPDFPITMGSDALNRKLEIEKSVIDLASINTELLNRKLYLDKLNRLEIPNVNIVPFKYLQQPTEPTKRDVPKRALIVILFALVGLMGSVGFVLVEHFVRERKREEEGLKLSQTKE
>NZ_CP016273.1|WP_002208586.1|3094619_3095924_-|inosine/guanosine-kinase
MKFPGKRKSKHYFPVNARDPLLQSVQAENEVSTSYIVGIDQTLVDIEAKVDEDFITRYGLSQGHSLVIEDDVAERLYQELTHNDLITHEFAGGTIGNTLHNYSVLADDRSVLLGTMCSNIKIGSYAYRYLCNTSSRTDLNYLQAVDGAIGRCFTLITENGERTFAISPGQMNQLRPESIPEEVIAGASALVLTAYLVRCKPGEPMPDATMQAIHYAKKHDVPVVMTLGTKYVIADNPQWWREFLNEHVSILAMNEDEAYELTGLNDPLMASDMALEWVDLVLCTAGPSGLYMAGYTEEAYKRQTQHPLLPGAIAEFNLYEFSRAMRKAHCVDPFRIYSHIAPYMGGPEKIMNTNGAGDGALSAVLHDITANGYHRNNVPNSSKHVRSYLSYSSLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWER
>NZ_CP016273.1|WP_002208585.1|3092831_3094523_+|Kef-family-K(+)-transporter
MHHSTPLITTIVGGLVLAFLFGTLAHRLRISPLVGYLAAGVLAGPFTPGFVADTSLAPELAEIGVILLMFGVGLHFSLKDLLAVKSIAIPGAIAQIAVATLLGMGLSHFLGWDLITGLVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLAMVLTLVLLPAFAGVMGNETTNLNQLFTELAITIGKVIAFITLMIVVGRRLVPWILAKTASTGSRELFTLAVLVLALGIAYGAVELFDVSFALGAFFAGMVLNESELSHRAAQDTLPLRDAFAVLFFVSVGMLFDPMILVNEPLAVIASLAIIIFGKSAIAFALVRLFGHSKRTALTISVSLAQIGEFAFILAGLGISLGLLSGHGRNLVLASAILSIMLNPLLFTLLDRYLAKTETMEDLILEEAVEEEKQIPVDLCNHVLLVGYGRVGSLLGAKLHAEGIPLVVIENSRPRVEALREQGINAVFGNAANADVMALGRLDCARWLLLTIPNGYEAGEIVASARIKRPDLEIIARAHYDDEVVYISDRGANQVVMGEREIANSMLNMLKIETLTEEDKMPVCPI
>NZ_CP016273.1|WP_002208584.1|3091382_3092597_+|MFS-transporter
MTDRSDTGCQQPVNVSVKRTSFSILGAISVSHLLNDMIQSLILAIYPLLQAEFSLSFAQIGLITLTYQLTASLLQPLIGLYTDKHPQPYSLPIGMGFTLSGILLLAVATTFPVVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSVFQVGGNFGSALGPLLAAIIIAPYGKGNVGWFSLAALLAIVVLLQVSKWYKLQQRASYGKVLKISSAKTLPKNKIISTLAILMVLIFSKYFYLTSISSYYTFYLIHKFGVSVQSAQIHLFVFLFAVAAGTIIGGPLGDKIGRKYVIWGSILGVAPFTLALPYASLYWTGILTVFIGVILASAFSAILVYAQELIPGKVGMVSGLFFGFAFGMGGIGAAVLGYVADLTSIELVYQICAFLPLLGIFTALLPNLDDK
>NZ_CP016273.1|WP_002208583.1|3089102_3089342_+|hypothetical-protein
MGYDAHKNDLNIKADLIALKYVVQTLVAVANSAHDNRLNQALDILIHEFESNANKNNDNQSIANAIANYLPDEPVIELV
>NZ_CP016273.1|WP_002208581.1|3088286_3088766_+|Cys-tRNA(Pro)/Cys-tRNA(Cys)-deacylase-YbaK
MTPAVVLLEKQKVPFTLHPYHHDAAETHFGDEAVKKLGLNADQVYKTLLVALNNDAKNLAVAVTPVATQLDLKKVARALGAKKAEMADPQLAQRTTGYLIGGISPLGQKKRLPTVIDSQAQEFVTIFVSGGKRGLDIELAAVDLCRLLQGVFADIAKRD
>NZ_CP016273.1|WP_002208580.1|3087213_3088023_+|TraB/GumN-family-protein
MDKLLRRIAKFLGIITPTTYAYPALDITLPGERHLHLVGSIHMGTAGMFPLPHTLLNKLNQADALIVEADITDATSSFGHSTVTEPLVDRLSEEYYPQLQRRCEELGSDPLAMTYLPAWQVALMLQAHQAQRLGLRGEYGIDYQLLKAAGAQEKEIIELEGAEMQLDLLKTLPDNGISLLHDTLLHWHTNARLLQTMIGWWLEHQPEKYQATLAPTFSHDMYDVLMLQRNKRWQQQLEQLAPGRYVVAVGALHLYGEGNLPELLRADNQ
>NZ_CP016273.1|WP_002208591.1|3103193_3104207_-|glycosyltransferase-family-4-protein
MKIIYDGIINSLQNMGGVTVYFSELVSRLPATDFYWYSYADEISGFGVGNVKIKSRLLERYRNFSLDTINYNSLSVFHSSYYRLPDFDIPIVTTVHDFTYEKFVNGPAKWVHSWQKNRAVNNSDLIICVSENTAKDLQMYCSVPSNKIRVIYNGVSDKYHYIKGVKITTNKVIFVGARGGYKNFDIAVKAISKTPHLELSVVGGGAFTSKELSLLNHYLPGRYHGLGRLSDEALNEAYNSAYALLYPSSYEGFGIPILEAMSAGCPVISVNVSSIPEVAGDAAILVQKPTIDELVDGLLAVESERSKLIGYGMKQAAKFSWDKCYQETLDVYKELNK
>NZ_CP016273.1|WP_002208592.1|3105673_3106816_-|glycosyltransferase
MILRKFFIICDTVYPDDSGGRKLSLGRIFEAKESGFKVSVLHYNYTNSDVSIARQFFLEHNIDYFYYIPAFSHKKSNLVRCANYISSVIKLTPEPYYYIMKDYGFKKFVLDNFEMSKNSTLSIESILLSGLLPWFNTFEGSIELVFHNVESDFYRQLSISSRSIIYKIFFFIESMKLSAIEKYLFNIKDENIYFVFLSEKDLEKYRLIFPEFQADIFINKNNLFIKEKIKRSVNFNKPFFLFPGGLNFPPNRYSLNWFLAAMSKRVSSLGVDILVTGSFNDDIKSQFSQYSCVKLVGYVSDIQLRELQSSCIAVISPIITGGGVKIKNIEAIKLKIPLIATKFSCEGIDERGANIYITDDEPGSFYITMKSVLNKTMSYK
>NZ_CP016273.1|WP_002215988.1|3107195_3107909_-|glycosyltransferase-family-2-protein
MKSNIIIDNSNSDDVLLTIAIPTYKRFGLLKETLKSVFSLEFNIPVEVIVVDNDPEHPELVLSEMAEFERYDFIYYKNIENYGMFGNWNQCLNLGRGKLITILHDDDLLCANFPRELERFLKEHGCHDDIPLIGFGHHLLDQRKSEDKVNKNILYKISKNIFNIYRKYLIKPKVVSITLNEIFWGNIFSGTLGVVMDRNKALSISGFDERNYPVSDYDFWIRWIQKYEARCYFRFYN
>NZ_CP016273.1|WP_002208593.1|3107919_3109263_-|hypothetical-protein
MKISSQMVWGLLNQGCNIFIPFVIMFMSYKYLPLEMASVWVIFLSMISLITLFDFGLSPAIVRNVSYVISGAQNLVKRGIDDIIIKDVISYPLLSRLLFDIKRIYLYLSLIAFFIIVIGGLWYFYYISPLDIKIEVAYSWVLFSSALIINLIYLYYVPVLTGLGEIENSYKANVFGRIIWFFLSLLVFIFSPSILLLSLSFVFSVFINRYLCYFFYIRNSHVKAIDKTEMEKKSTVPFIGHNAAKLGVVSLGSFLINRSTTLIVGIVCPIVTAGQFVLSMQVFFALMAISNILLSIKIPEISQAVAKREHYTVKILIYKVVAFSSSIYLLGFVTFLILAEYVLPTIGVSLSFLPLDYLLILGLIYFLEMNHSICATIITSKNNVPFVFVSLFSGGLIILLSIMLSVHFKYGVVGLILAQGIVQLMYNNWKWPLMVYSEFIKNNIEDR
>NZ_CP016273.1|WP_002208594.1|3109336_3110620_-|NAD(P)/FAD-dependent-oxidoreductase
MDMKFCKNRYINTVILGAGVAGLGAALKAREVNIEYEIFEAKASAGGLLDNFVIDGYRFDNAVHLSFATEEKVRDIFDRTPYFSHSPDAVNFETDKWLKHPVQNNLYPLPAIEKVTLIESLIHRPESELADNYESWLIHQYGNEIAKRYPMRYTRKYWQCNANELSVSWIGNRLRRAKLSEILYGAFTDDTPNDYYAKEMRYPKKGGFKSFIQPLIDESIINYNYEVTEIDLSGKTIKFSNGVIISYENLINTLPLPLFIEFCGANVPTSVKKSASKLEATSLDLISVGFNKSIIKDLWFYIYDEDIYASRAYSPSVKSSDNVPDGCSSLQFEIYNPGRDSQYTVQELKDNVMYAMKKMGVANDEDIVFLHHKRLPWGNVVFKKDMEKYRDIVREYIFDNQVKSVGRFGEWDYLWSNQSFLSGYSSI
>NZ_CP016273.1|WP_002208595.1|3110620_3111478_-|NAD-dependent-epimerase/dehydratase
MKILITGVSGYLGSQLANALMLEHEVVGTVRAGSVCNRITDIGNVNLINVTDSGWIDKVLSFSPDVVINTAALYGRKGELLSELVDANIQFPLRILEMLVSTGKGLFFQCGTSLPADVSQYALTKNQFTELAREYCNKFSGKFIELKLEHFFGPFDDSTKFTTYVINSCRSHSDLKLTAGLQRRDFIYINDLINAFKIMISKSESLISGESISIGSGHAVTIKEFVETVAKMTSYQGNLQFGAIPTRENELMYSCASLARIQELGWLCQYSLNSAIKDTLNRMRV
>NZ_CP016273.1|WP_002208596.1|3111514_3112828_-|lipopolysaccharide-biosynthesis-protein-RfbH
MSQEELRQQIAELVAQYAETAMAPKPFEAGKSVVPPSGKVIGTKELQLMVEASLDGWLTTGRFNDAFEKKLGEYLGVPYVLTTTSGSSANLLALTALTSPKLGVRALKPGDEVITVAAGFPTTVNPTIQNGLIPVFVDVDIPTYNVNASLIEAAVSDKTKAIMIAHTLGNLFDLAEVRRVADKYNLWLIEDCCDALGSTYDGKMAGTFGDIGTVSFYPAHHITMGEGGAVFTQSAELKSIIESFRDWGRDCYCAPGCDNTCKKRFGQQLGSLPFGYDHKYTYSHLGYNLKITDMQAACGLAQLERIEEFVEKRKANFKYLKDALQSCADFIELPEATENSDPSWFGFPITLKEDSGVSRIDLVKFLDEAKVGTRLLFAGNLTRQPYFHDVKYRVVGELTNTDRIMNQTFWIGIYPGLTHDHLDYVVSKFEEFFGLNF
>NZ_CP016273.1|WP_002229992.1|3112845_3113919_-|CDP-glucose-4,6-dehydratase
MINNSFWQGKRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLPPPTVPSLFETARVADGMQSEIGDIRDQNKLLESIREFQPEIVFHMAAQPLVRLSYSEPVETYSTNVMGTVYLLEAIRHVGGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYRNSFFNPANYGQHGTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPVIIRNPHAIRPWQHVLEPLSGYLLLAQKLYTDGAEYAEGWNFGPNDADATPVKNIVEQMVKYWGEGASWQLDGNAHPHEAHYLKLDCSKAKMQLGWHPRWNLNTTLEYIVGWHKNWLSGTDMHEYSITEINNYMNTK
>NZ_CP016273.1|WP_002208597.1|3113923_3114697_-|glucose-1-phosphate-cytidylyltransferase
MKAVILAGGLGTRLSEETVVKPKPMVEIGGKPILWHIMKLYSSYGINDFVICCGYKGYVIKEYFANYFMHMSDITFCMRDNEMIVHQKRVEPWNVTLVDTGEDSMTGGRLRRVKDYVKDDEAFCFTYGDGVSDVNIAELIEFHKSHGKQATLTATYPPGRFGALDIKDKQVRSFKEKPKGDGALINGGYFVLSPKVIDLIDGDKSTWEQEPLMTLAAQGELMAFEHAGFWQPMDTLRDKIYLHELWEEGRAPWKVWE
>NZ_CP016273.1|WP_002208598.1|3114734_3115724_-|CDP-6-deoxy-delta-3,4-glucoseen-reductase
MSLNVKLHPSGIIFTSDGTSTILDAALDSNIHIEYSCKDGTCGSCKAILISGEVDSAENTFLTEEDVAKGAILTCCSKAKSDIELDVNYYPELSHIQKKTYPCKLDSIEFIGEDIAILSLRLPPTAKIQYLAGQYIDLIINGQRRSYSIANAPGGNGNIELHVRKVVNGVFSNIIFNELKLQQLLRIEGPQGTFFVREDNLPIVFLAGGTGFAPVKSMVEALINKNDQRQVHIYWGMPAGHNFYSDIANEWAIKHPNIHYVPVVSGDDSTWTGATGFVHQAVLEDIPDLSLFNVYACGSLAMITAARNDFINHGLAENKFFSDAFVPSK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NZ_CP016273_3	3.7\|2412024\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2412024-2412055	32	NZ_CP016273.1	2006378-2006409	1.0
NZ_CP016273_3	3.8\|2412084\|33\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2412084-2412116	33	NZ_CP016273.1	2012258-2012290	1.0
NZ_CP016273_4	4.1\|2537649\|33\|NZ_CP016273\|PILER-CR,CRISPRCasFinder,CRT	2537649-2537681	33	NZ_CP016273.1	2014630-2014662	1.0
NZ_CP016273_4	4.5\|2537892\|32\|NZ_CP016273\|CRISPRCasFinder,CRT	2537892-2537923	32	NZ_CP016273.1	2011944-2011975	1.0
NZ_CP016273_5	5.2\|3101019\|16\|NZ_CP016273\|CRISPRCasFinder	3101019-3101034	16	NZ_CP016273.1	3101047-3101062	1.0
NZ_CP016273_5	5.2\|3101019\|16\|NZ_CP016273\|CRISPRCasFinder	3101019-3101034	16	NZ_CP016273.1	3101054-3101069	1.0
NZ_CP016273_5	5.2\|3101019\|16\|NZ_CP016273\|CRISPRCasFinder	3101019-3101034	16	NZ_CP016273.1	3101061-3101076	1.0

1. spacer 3.7|2412024|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to position: 2006378-2006409, mismatch: 0, identity: 1.0

aaaaagaatttgggattaaagttacccatcag	CRISPR spacer
aaaaagaatttgggattaaagttacccatcag	Protospacer
********************************

2. spacer 3.8|2412084|33|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to position: 2012258-2012290, mismatch: 0, identity: 1.0

tcaatgcctgaatctctggcgtgatagctgcgg	CRISPR spacer
tcaatgcctgaatctctggcgtgatagctgcgg	Protospacer
*********************************

3. spacer 4.1|2537649|33|NZ_CP016273|PILER-CR,CRISPRCasFinder,CRT matches to position: 2014630-2014662, mismatch: 0, identity: 1.0

ccggcggtgatggcaattctacgtgggttcgtt	CRISPR spacer
ccggcggtgatggcaattctacgtgggttcgtt	Protospacer
*********************************

4. spacer 4.5|2537892|32|NZ_CP016273|CRISPRCasFinder,CRT matches to position: 2011944-2011975, mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

5. spacer 5.2|3101019|16|NZ_CP016273|CRISPRCasFinder matches to position: 3101047-3101062, mismatch: 0, identity: 1.0

agcaaatagcaaatag	CRISPR spacer
agcaaatagcaaatag	Protospacer
****************

6. spacer 5.2|3101019|16|NZ_CP016273|CRISPRCasFinder matches to position: 3101054-3101069, mismatch: 0, identity: 1.0

agcaaatagcaaatag	CRISPR spacer
agcaaatagcaaatag	Protospacer
****************

7. spacer 5.2|3101019|16|NZ_CP016273|CRISPRCasFinder matches to position: 3101061-3101076, mismatch: 0, identity: 1.0

agcaaatagcaaatag	CRISPR spacer
agcaaatagcaaatag	Protospacer
****************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016273_4	4.5\|2537892\|32\|NZ_CP016273\|CRISPRCasFinder,CRT	2537892-2537923	32	MT374852	Yersinia phage vB_YpM_3, complete genome	12-43	0	1.0
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK820641	Gordonia phage EnalisNailo, complete genome	34088-34119	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK878898	Gordonia phage Zameen, complete genome	34513-34544	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK919483	Gordonia phage Suscepit, complete genome	34514-34545	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK284520	Gordonia phage Lilas, complete genome	35799-35830	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK016492	Gordonia phage Bialota, complete genome	35265-35296	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK820642	Gordonia phage Polly, complete genome	33956-33987	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NC_041883	Gordonia phage Attis, complete genome	31646-31677	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK814755	Gordonia phage Antonio, complete genome	34513-34544	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK875796	Gordonia phage Tayonia, complete genome	34513-34544	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK801734	Gordonia phage LordFarquaad, complete genome	31627-31658	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	MK433274	Gordonia phage Bradissa, complete genome	34554-34585	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	KU963257	Gordonia phage Kita, complete genome	34522-34553	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NC_031251	Gordonia phage SoilAssassin, complete genome	31645-31676	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NC_031097	Gordonia phage Zirinka, complete genome	35253-35284	6	0.812
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NZ_CP005086	Sphingobium sp. TKS plasmid pTK2, complete sequence	138555-138586	6	0.812
NZ_CP016273_3	3.1\|2411664\|32\|NZ_CP016273\|CRISPRCasFinder,CRT	2411664-2411695	32	CP049262	Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence	69636-69667	7	0.781
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	JF974294	Aeromonas phage pIS4-A genomic sequence	21965-21996	7	0.781
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NC_021534	Vibrio phage pYD38-A genomic sequence	3299-3330	7	0.781
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	440819-440850	7	0.781
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	282870-282901	7	0.781
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	KJ433975	Mycobacterium phage 40BC, complete genome	23231-23262	7	0.781
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	KJ433973	Mycobacterium phage 39HC, complete genome	23231-23262	7	0.781
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NC_024145	Mycobacterium phage Hosp, complete genome	21427-21458	7	0.781
NZ_CP016273_3	3.6\|2411964\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411964-2411995	32	NZ_CP024873	Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence	14979-15010	8	0.75
NZ_CP016273_3	3.7\|2412024\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2412024-2412055	32	NZ_CP047125	Lactobacillus hilgardii strain FLUB plasmid unnamed4	1912-1943	8	0.75
NZ_CP016273_3	3.2\|2411724\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411724-2411755	32	NZ_CP031943	Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence	4006-4037	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	MF679145	Escherichia coli plasmid pBJ114-96, complete sequence	37586-37617	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_KP453775	Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence	60831-60862	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP021340	Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence	67671-67702	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP021336	Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence	67672-67703	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP040920	Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence	33435-33466	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP024832	Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence	33830-33861	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP024817	Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence	62769-62800	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	15616-15647	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	112580-112611	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP023961	Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence	16858-16889	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	AP023222	Escherichia coli M505 plasmid pM505-b DNA, complete genome	93734-93765	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	AP023233	Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome	47570-47601	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP019075	Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence	16520-16551	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP015837	Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence	3287-3318	9	0.719
NZ_CP016273_3	3.3\|2411784\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411784-2411815	32	NZ_CP011063	Escherichia coli str. Sanji plasmid pSJ_98, complete sequence	37637-37668	9	0.719
NZ_CP016273_4	4.4\|2537831\|33\|NZ_CP016273\|PILER-CR,CRISPRCasFinder,CRT	2537831-2537863	33	NZ_CP040366	Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence	923-955	9	0.727
NZ_CP016273_3	3.4\|2411844\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411844-2411875	32	NZ_JX627581	Methylobacterium oryzae CBMB20 plasmid pMOC2, complete sequence	30496-30527	10	0.688
NZ_CP016273_3	3.6\|2411964\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411964-2411995	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	815356-815387	11	0.656
NZ_CP016273_3	3.6\|2411964\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411964-2411995	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	820287-820318	11	0.656
NZ_CP016273_3	3.6\|2411964\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411964-2411995	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2180994-2181025	11	0.656
NZ_CP016273_3	3.6\|2411964\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2411964-2411995	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2185925-2185956	11	0.656

1. spacer 4.5|2537892|32|NZ_CP016273|CRISPRCasFinder,CRT matches to MT374852 (Yersinia phage vB_YpM_3, complete genome) position: , mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK820641 (Gordonia phage EnalisNailo, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

3. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK878898 (Gordonia phage Zameen, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

4. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK919483 (Gordonia phage Suscepit, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

5. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK284520 (Gordonia phage Lilas, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

6. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK016492 (Gordonia phage Bialota, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

7. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK820642 (Gordonia phage Polly, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

8. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_041883 (Gordonia phage Attis, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

9. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK814755 (Gordonia phage Antonio, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

10. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK875796 (Gordonia phage Tayonia, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

11. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK801734 (Gordonia phage LordFarquaad, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

12. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MK433274 (Gordonia phage Bradissa, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

13. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to KU963257 (Gordonia phage Kita, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

14. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_031251 (Gordonia phage SoilAssassin, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

15. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_031097 (Gordonia phage Zirinka, complete genome) position: , mismatch: 6, identity: 0.812

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
gtcgtc-cgccgtgatcctgagcgcgctcgcga	Protospacer
 ***.* . ****** **********.******

16. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP005086 (Sphingobium sp. TKS plasmid pTK2, complete sequence) position: , mismatch: 6, identity: 0.812

tcgccattccgtgaacctgagcgcgttcgcga--	CRISPR spacer
tcgcctttccctgaacctga--gcgatcgtgacc	Protospacer
***** **** *********  *** ***.**

17. spacer 3.1|2411664|32|NZ_CP016273|CRISPRCasFinder,CRT matches to CP049262 (Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence) position: , mismatch: 7, identity: 0.781

tcaggggactggcgaacaatgtctttcatgat	CRISPR spacer
acgtcgcgctggcgaacaatctctttcatgat	Protospacer
 *.  * .************ ***********

18. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to JF974294 (Aeromonas phage pIS4-A genomic sequence) position: , mismatch: 7, identity: 0.781

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attacctgaatggcatttgctttatgcctgat	Protospacer
****.************* ****.   * ***

19. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_021534 (Vibrio phage pYD38-A genomic sequence) position: , mismatch: 7, identity: 0.781

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attacctgaatggcatttgctttatgcctgat	Protospacer
****.************* ****.   * ***

20. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

----tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
cacctcgc----tcgggaacctgggcgcgttcgcga	Protospacer
    ****    .** *******.************

21. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 7, identity: 0.781

----tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
cacctcgc----tcgggaacctgggcgcgttcgcga	Protospacer
    ****    .** *******.************

22. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to KJ433975 (Mycobacterium phage 40BC, complete genome) position: , mismatch: 7, identity: 0.781

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
cccgccg-cccgtgtacccgagcgcgttcgcgc	Protospacer
 .****. .***** ***.*************

23. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to KJ433973 (Mycobacterium phage 39HC, complete genome) position: , mismatch: 7, identity: 0.781

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
cccgccg-cccgtgtacccgagcgcgttcgcgc	Protospacer
 .****. .***** ***.*************

24. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_024145 (Mycobacterium phage Hosp, complete genome) position: , mismatch: 7, identity: 0.781

-tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
cccgccg-cccgtgtacccgagcgcgttcgcgc	Protospacer
 .****. .***** ***.*************

25. spacer 3.6|2411964|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024873 (Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence) position: , mismatch: 8, identity: 0.75

tcggtcaaacaaatttaggcgacgatttaaca	CRISPR spacer
ttactcaaacaagttgaggcgacgattctaaa	Protospacer
*.. ********.** ***********. * *

26. spacer 3.7|2412024|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047125 (Lactobacillus hilgardii strain FLUB plasmid unnamed4) position: , mismatch: 8, identity: 0.75

aaaaagaatttgggattaaagttacccatcag	CRISPR spacer
taaaagcttttgggattaaagttattcaaaat	Protospacer
 *****  ****************..**  *

27. spacer 3.2|2411724|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031943 (Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

gaaaaggtaagatgggcaagcttctagtagtt	CRISPR spacer
ttatgagaaagatgggcaagcttttagtggta	Protospacer
  * ..* ***************.****.**

28. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to MF679145 (Escherichia coli plasmid pBJ114-96, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

29. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KP453775 (Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

30. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021340 (Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

31. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021336 (Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

32. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040920 (Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

33. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024832 (Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

34. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024817 (Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

35. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

36. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat-----	CRISPR spacer
attatctgattggcagtttctttaac-----tgttta	Protospacer
********* ***** *******..*     *

37. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023961 (Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

38. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to AP023222 (Escherichia coli M505 plasmid pM505-b DNA, complete genome) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

39. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to AP023233 (Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

40. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019075 (Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

41. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015837 (Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

42. spacer 3.3|2411784|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011063 (Escherichia coli str. Sanji plasmid pSJ_98, complete sequence) position: , mismatch: 9, identity: 0.719

attatctgaatggcattttctttggcgcagat	CRISPR spacer
attatctgattggcagtttctttaactgtttt	Protospacer
********* ***** *******..*     *

43. spacer 4.4|2537831|33|NZ_CP016273|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040366 (Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

ccgaaatcatcagatgtaattaagatttttgct	CRISPR spacer
aatggattatcagatgtaattaagtttttttcc	Protospacer
   ..**.**************** ***** *.

44. spacer 3.4|2411844|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_JX627581 (Methylobacterium oryzae CBMB20 plasmid pMOC2, complete sequence) position: , mismatch: 10, identity: 0.688

tcgccattccgtgaacctgagcgcgttcgcga	CRISPR spacer
ctaacgagccgtgaacctcagcgcattcgcgt	Protospacer
... *.  ********** *****.******

45. spacer 3.6|2411964|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

tcggtcaaacaaatttaggcgacgatttaaca	CRISPR spacer
gtggtcaaacaaatttaggcaaggagccgctg	Protospacer
 .******************.* ** ... ..

46. spacer 3.6|2411964|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

tcggtcaaacaaatttaggcgacgatttaaca	CRISPR spacer
gtggtcaaacaaatttaggcaaggagccgctg	Protospacer
 .******************.* ** ... ..

47. spacer 3.6|2411964|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 11, identity: 0.656

tcggtcaaacaaatttaggcgacgatttaaca	CRISPR spacer
gtggtcaaacaaatttaggcaaggagccgctg	Protospacer
 .******************.* ** ... ..

48. spacer 3.6|2411964|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 11, identity: 0.656

tcggtcaaacaaatttaggcgacgatttaaca	CRISPR spacer
gtggtcaaacaaatttaggcaaggagccgctg	Protospacer
 .******************.* ** ... ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

305803 : 362405

Escherichia_phage(33.33%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|305803_306826_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002397472.1\|306913_307165_+	sugar transporter	NA	NA	NA	NA
WP_002210456.1\|307405_308008_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_002210455.1\|308022_309453_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_002210454.1\|309454_310546_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_002210453.1\|310548_312111_-	2-isopropylmalate synthase	NA	NA	NA	NA
WP_002213775.1\|312257_312716_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002210452.1\|313144_313360_-	hypothetical protein	NA	NA	NA	NA
WP_002216434.1\|314037_314994_+	transcriptional regulator LeuO	NA	NA	NA	NA
WP_002216437.1\|315530_317336_+	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	3.5e-38	23.2
WP_002228103.1\|317795_319523_+	acetolactate synthase 3 large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	7.8e-59	29.4
WP_002210448.1\|319525_320020_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_002213759.1\|320218_320677_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002210447.1\|321181_322192_+	catabolite repressor/activator	NA	NA	NA	NA
WP_002210446.1\|322322_322763_-	L-alanine exporter AlaE	NA	NA	NA	NA
WP_087768171.1\|323220_323310_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002210443.1\|323864_324323_+	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_002210442.1\|324325_325288_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_002210441.1\|325284_325602_+	cell division protein FtsL	NA	NA	NA	NA
WP_002210440.1\|325667_327431_+	peptidoglycan glycosyltransferase FtsI	NA	NA	NA	NA
WP_002210439.1\|327417_328905_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
WP_002210438.1\|328901_330278_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_002210437.1\|330271_331354_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_002210436.1\|331356_332673_+	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_002210435.1\|332672_333875_+	cell division protein FtsW	NA	NA	NA	NA
WP_002210434.1\|333871_334942_+	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_002216457.1\|335079_336555_+	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_002210432.1\|336547_337468_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_002228100.1\|337469_338297_+	cell division protein FtsQ	NA	NA	NA	NA
WP_002210431.1\|338323_339580_+	cell division protein FtsA	NA	NA	NA	NA
WP_002210430.1\|339652_340804_+	cell division protein FtsZ	NA	NA	NA	NA
WP_002228285.1\|340903_341824_+	UDP-3-O-acyl-N-acetylglucosamine deacetylase	NA	NA	NA	NA
WP_002210428.1\|341990_342515_-	DUF721 domain-containing protein	NA	NA	NA	NA
WP_002210427.1\|342543_343077_+	secA regulator SecM	NA	NA	NA	NA
WP_002210426.1\|343154_345869_+	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_002210424.1\|346163_346550_+	8-oxo-dGTP diphosphatase MutT	A0A0B5CYJ3	Rhizoctonia_fumigata_mycovirus	8.4e-06	30.4
WP_001297096.1\|346811_347591_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|347590_348613_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002210421.1\|348891_349287_-	DoxX family protein	NA	NA	NA	NA
WP_002210420.1\|349590_349875_-	YqjK-like family protein	NA	NA	NA	NA
WP_002210419.1\|349871_350267_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_002210418.1\|350269_350575_-	DUF883 domain-containing protein	NA	NA	NA	NA
WP_002210416.1\|350729_351110_-	DUF1090 domain-containing protein	NA	NA	NA	NA
WP_002210415.1\|351335_351725_-	EnvZ/OmpR regulon moderator MzrA	NA	NA	NA	NA
WP_002210414.1\|351721_352420_-	DedA family protein	NA	NA	NA	NA
WP_002218957.1\|352697_353231_-	hypothetical protein	NA	NA	NA	NA
WP_002210412.1\|353479_354274_-	transcriptional regulator ExuR	NA	NA	NA	NA
WP_002353699.1\|354536_355838_-	MFS transporter	NA	NA	NA	NA
WP_002210410.1\|356585_357995_+	glucuronate isomerase	NA	NA	NA	NA
WP_002210409.1\|358193_359645_+	tagaturonate reductase	NA	NA	NA	NA
WP_002210408.1\|359655_361146_+	altronate dehydratase	NA	NA	NA	NA
WP_002210407.1\|361298_361829_+	YgjV family protein	NA	NA	NA	NA
WP_002213775.1\|361946_362405_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1

DBSCAN-SWA_2

576560 : 594069

Tupanvirus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211388.1\|576560_582380_-	non-ribosomal peptide synthetase	A0A2K9L3I8	Tupanvirus	1.3e-41	31.3
WP_002214915.1\|582392_584081_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	3.1e-36	25.0
WP_002211387.1\|584088_590547_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	8.5e-42	25.0
WP_001297096.1\|590754_591534_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|591533_592556_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_099156340.1\|592637_592934_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_002211384.1\|593274_594069_-	thymidylate synthase	R4IFY1	Cronobacter_phage	8.9e-119	62.9

DBSCAN-SWA_3

748110 : 823930

Escherichia_phage(20.0%)

protease,tRNA,plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|748110_749133_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002213759.1\|749316_749775_-\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002209965.1\|750082_752077_-	transketolase	NA	NA	NA	NA
WP_002209967.1\|752567_753320_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_071525520.1\|753465_753576_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002209968.1\|753609_753930_-	non-heme iron oxygenase ferredoxin subunit	NA	NA	NA	NA
WP_002209969.1\|754089_756069_-	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_002209971.1\|757275_758430_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.7e-126	62.1
WP_002228059.1\|758622_759135_+\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_002209973.1\|759232_759940_+	deoxyribonuclease I	NA	NA	NA	NA
WP_002209975.1\|760191_760923_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_002209976.1\|760948_761908_+	glutathione synthase	NA	NA	NA	NA
WP_002209977.1\|762023_762587_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_002209978.1\|762586_763009_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_002209979.1\|763188_764073_+	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	3.1e-80	51.0
WP_002209980.1\|764076_765192_+	agmatine deiminase	M1I1E2	Acanthocystis_turfacea_Chlorella_virus	3.0e-96	50.7
WP_002209981.1\|765300_766425_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_002215609.1\|766444_767143_+	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_002209983.1\|767275_768097_+	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_002209984.1\|768384_768939_+	YggT family protein	NA	NA	NA	NA
WP_002215612.1\|768935_769226_+	YggU family protein	NA	NA	NA	NA
WP_002215614.1\|769325_769919_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_002209987.1\|769911_771042_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_002224905.1\|771231_780564_-	phage minor structural protein	NA	NA	NA	NA
WP_011566213.1\|781061_781307_-	DUF2884 family protein	NA	NA	NA	NA
WP_002228656.1\|781264_781795_-	DUF2884 family protein	NA	NA	NA	NA
WP_002209989.1\|781906_782833_-	glutaminase B	NA	NA	NA	NA
WP_002209990.1\|782943_783270_-	YggL family protein	NA	NA	NA	NA
WP_002209991.1\|783269_783989_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_002228057.1\|784326_785442_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_002209994.1\|785619_785892_+	oxidative damage protection protein	NA	NA	NA	NA
WP_002209995.1\|786074_787151_+	membrane-bound lytic murein transglycosylase MltC	NA	NA	NA	NA
WP_002209997.1\|787450_788551_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002209998.1\|788654_790688_+	TonB-dependent siderophore receptor	A0A0P0I887	Acinetobacter_phage	4.5e-05	26.1
WP_002209999.1\|790770_791754_-	ABC transporter permease	NA	NA	NA	NA
WP_002210000.1\|791786_793286_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-19	31.7
WP_002210001.1\|793331_794291_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_002210002.1\|794846_797009_-	ornithine decarboxylase SpeF	NA	NA	NA	NA
WP_002210005.1\|798337_798973_-	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_086016632.1\|799575_800273_-\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	1.3e-60	48.5
WP_002210008.1\|800368_801136_-	hypothetical protein	NA	NA	NA	NA
WP_002210009.1\|801122_803420_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_002210010.1\|803435_804071_-	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_002216110.1\|805295_805490_-	hypothetical protein	NA	NA	NA	NA
WP_016590715.1\|805653_806001_-	hypothetical protein	NA	NA	NA	NA
WP_002210011.1\|806144_808367_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_002210012.1\|808381_810730_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.1e-18	33.3
WP_002210013.1\|810726_813375_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	4.8e-92	29.5
WP_002210014.1\|813792_814284_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002228049.1\|814287_816024_-	OmpA family protein	NA	NA	NA	NA
WP_002210015.1\|816023_816710_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002211664.1\|816706_818059_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002215896.1\|818070_819615_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211662.1\|819657_820158_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002215900.1\|822433_822829_-	lipoprotein	NA	NA	NA	NA
WP_002215902.1\|823279_823930_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_4

966093 : 1021235

Escherichia_phage(31.25%)

protease,integrase,transposase

attL 966025:966084|attR 1011805:1013761

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
966025:966084	attL	NA	NA	NA	NA
WP_001297096.1\|966093_966873_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|966872_967895_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002215951.1\|968499_968817_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	2.0e-13	48.1
WP_002210705.1\|968822_969137_+	putative addiction module antidote protein	NA	NA	NA	NA
WP_002210707.1\|969485_970574_-	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.4e-114	60.4
WP_002215950.1\|970570_971530_-	toprim domain-containing protein	A0A1W6JPG0	Morganella_phage	1.6e-50	41.0
WP_002215949.1\|971522_972065_-	ash family protein	NA	NA	NA	NA
WP_002210709.1\|972064_972265_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.6e-08	51.7
WP_002210710.1\|972257_973145_-\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_002215946.1\|973952_974180_+	hypothetical protein	NA	NA	NA	NA
WP_002215945.1\|974341_976012_-	hypothetical protein	NA	NA	NA	NA
WP_002210712.1\|976062_977151_-	DUF4297 domain-containing protein	NA	NA	NA	NA
WP_002210713.1\|977229_978429_-\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	2.2e-108	50.2
WP_002213775.1\|978652_979111_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002210714.1\|979745_980228_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	3.4e-28	46.2
WP_011055694.1\|980286_980823_+	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_002210716.1\|980815_981100_+	RnfH family protein	NA	NA	NA	NA
WP_002210717.1\|981249_981591_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_002210718.1\|981704_983366_-	DNA repair protein RecN	NA	NA	NA	NA
WP_002210719.1\|983452_984334_-	NAD(+) kinase	NA	NA	NA	NA
WP_002210720.1\|984457_985036_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_002210721.1\|985143_986424_-	citrate synthase	NA	NA	NA	NA
WP_002210722.1\|987133_987523_+	succinate dehydrogenase cytochrome b556 subunit	NA	NA	NA	NA
WP_002210723.1\|987516_987864_+	succinate dehydrogenase membrane anchor subunit	NA	NA	NA	NA
WP_002210724.1\|987864_989631_+	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_002210725.1\|989680_990397_+	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_002210727.1\|993588_994812_+	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_002210728.1\|994924_996091_+	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_002210729.1\|996090_996963_+	succinate--CoA ligase subunit alpha	A0A2K9L1S3	Tupanvirus	3.6e-20	34.7
WP_002210730.1\|997729_999298_+	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_002210731.1\|999312_1000452_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_002210732.1\|1000464_1000599_+	cytochrome bd-I oxidase subunit CydX	NA	NA	NA	NA
WP_011191945.1\|1000588_1000876_+	cyd operon protein YbgE	NA	NA	NA	NA
WP_002210734.1\|1001007_1001409_+	tol-pal system-associated acyl-CoA thioesterase	NA	NA	NA	NA
WP_002210735.1\|1001408_1002095_+	Tol-Pal system protein TolQ	NA	NA	NA	NA
WP_002210736.1\|1002107_1002536_+	colicin uptake protein TolR	NA	NA	NA	NA
WP_002210737.1\|1002647_1003814_+	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_002210738.1\|1003933_1005226_+	Tol-Pal system protein TolB	NA	NA	NA	NA
WP_002210739.1\|1005276_1005783_+	peptidoglycan-associated lipoprotein Pal	NA	NA	NA	NA
WP_002210740.1\|1005792_1006602_+	cell division protein CpoB	NA	NA	NA	NA
WP_002210741.1\|1007437_1008499_+	quinolinate synthase NadA	NA	NA	NA	NA
WP_002210742.1\|1008620_1009346_+	nicotinamide riboside transporter PnuC	A0A2I7SAC7	Vibrio_phage	8.7e-20	28.6
WP_002210743.1\|1009460_1010399_-	CDF family zinc transporter ZitB	A0A1V0SED0	Indivirus	1.2e-10	42.0
WP_002210744.1\|1010847_1011864_+	3-deoxy-7-phosphoheptulonate synthase AroG	A0A0B6VT43	Edwardsiella_phage	2.8e-72	46.8
WP_001297096.1\|1011873_1012653_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1012652_1013675_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002210745.1\|1013733_1013859_+	hypothetical protein	NA	NA	NA	NA
1011805:1013761	attR	NA	NA	NA	NA
WP_002210746.1\|1014040_1014793_-	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_002210747.1\|1015139_1015475_-	phosphate starvation-inducible protein PsiF	NA	NA	NA	NA
WP_002216812.1\|1015767_1016664_-	galactose-1-epimerase	NA	NA	NA	NA
WP_002216814.1\|1016684_1016837_-	hypothetical protein	NA	NA	NA	NA
WP_002210748.1\|1016830_1017982_-	galactokinase	NA	NA	NA	NA
WP_002210749.1\|1017978_1019031_-	galactose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_002210750.1\|1019040_1020057_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	3.0e-79	44.8
WP_002210751.1\|1020416_1021235_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_5

1043941 : 1155152

Clostridium_phage(13.16%)

protease,holin,plate,transposase,tail,coat,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|1043941_1044400_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002220180.1\|1044628_1046332_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	9.4e-57	31.5
WP_002218281.1\|1046354_1047827_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_002218278.1\|1047884_1048481_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_002228035.1\|1048845_1050894_+\|holin	choline transporter	A0A2I7QNT1	Vibrio_phage	1.4e-19	28.5
WP_002214199.1\|1051125_1052019_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002214197.1\|1052056_1052905_-	DMT family transporter	NA	NA	NA	NA
WP_002214195.1\|1053250_1054114_+	xanthosine phosphorylase	Q5YBA4	Grouper_iridovirus	2.3e-51	40.7
WP_002213775.1\|1055042_1055501_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002210776.1\|1055915_1056845_+	DUF4097 domain-containing protein	NA	NA	NA	NA
WP_002228612.1\|1057144_1058083_+\|tRNA	tRNA dihydrouridine(16) synthase DusC	NA	NA	NA	NA
WP_002210778.1\|1058156_1058336_-	hypothetical protein	NA	NA	NA	NA
WP_002210780.1\|1058674_1059610_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_002210781.1\|1059730_1061443_-	D-lactate dehydrogenase	NA	NA	NA	NA
WP_002210782.1\|1061652_1062192_+	class IV adenylate cyclase	NA	NA	NA	NA
WP_002214185.1\|1062217_1062559_-	HNH nuclease family protein	NA	NA	NA	NA
WP_002210785.1\|1062871_1063975_+	suppressor of fused domain protein	NA	NA	NA	NA
WP_002210786.1\|1064159_1064408_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002210787.1\|1064615_1065452_+	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.1e-17	30.1
WP_002210788.1\|1065488_1066418_+	phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002210789.1\|1066520_1067381_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_002210790.1\|1067383_1068265_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_002210791.1\|1068510_1068984_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.7e-37	50.7
WP_002210792.1\|1069418_1070687_+	urea ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002210793.1\|1070810_1072412_+	urea ABC transporter permease subunit UrtB	NA	NA	NA	NA
WP_002210794.1\|1072411_1073488_+	urea ABC transporter permease subunit UrtC	NA	NA	NA	NA
WP_002210795.1\|1073484_1074321_+	urea ABC transporter ATP-binding protein UrtD	A0A285PWH2	Cedratvirus	4.2e-10	28.2
WP_002223523.1\|1074414_1075113_+	urea ABC transporter ATP-binding subunit UrtE	A0A2H4PQG7	Staphylococcus_phage	6.4e-12	25.6
WP_002210797.1\|1075227_1076085_+	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_002210798.1\|1076108_1077524_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_002210799.1\|1077678_1078533_-	3-mercaptopyruvate sulfurtransferase	NA	NA	NA	NA
WP_002214183.1\|1079268_1079736_+	glycine/betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_079993142.1\|1079739_1080201_+	hypothetical protein	NA	NA	NA	NA
WP_002210801.1\|1080461_1081616_+	ABC transporter permease	NA	NA	NA	NA
WP_002210802.1\|1081612_1082551_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.4e-23	33.5
WP_002353933.1\|1082685_1083384_+	ABC transporter permease	NA	NA	NA	NA
WP_002210804.1\|1083867_1085202_+	arginine/agmatine antiporter	NA	NA	NA	NA
WP_002210805.1\|1085271_1087578_+	arginine decarboxylase	NA	NA	NA	NA
WP_002210806.1\|1087695_1087899_-	hypothetical protein	NA	NA	NA	NA
WP_002210807.1\|1088023_1088914_-	drug/metabolite exporter YedA	NA	NA	NA	NA
WP_002210809.1\|1089325_1090441_-	porin OmpF2	Q1MVN1	Enterobacteria_phage	2.1e-110	54.5
WP_002210810.1\|1090710_1092891_+	ATP-dependent DNA helicase DinG	A0A127AW80	Bacillus_phage	1.1e-44	26.3
WP_002210811.1\|1092958_1094398_-	catalase	A0A2K9L0T1	Tupanvirus	4.9e-99	38.8
WP_002210812.1\|1094758_1095301_+	YfaZ family protein	NA	NA	NA	NA
WP_002221775.1\|1095557_1096766_-	tyrosine transporter TyrP	NA	NA	NA	NA
WP_002210814.1\|1097384_1098578_+	nicotinamide mononucleotide deamidase-related protein YfaY	NA	NA	NA	NA
WP_002210815.1\|1098635_1099145_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_002210816.1\|1099179_1099437_-	2Fe-2S ferredoxin-like protein	G9IAA2	Pseudomonas_phage	4.0e-20	54.9
WP_002210817.1\|1099440_1100571_-	ribonucleotide-diphosphate reductase subunit beta	G9IAA3	Pseudomonas_phage	7.6e-172	78.6
WP_002210818.1\|1100733_1103022_-	ribonucleoside-diphosphate reductase subunit alpha	I3UMG3	Colwellia_phage	1.1e-286	64.9
WP_002210820.1\|1103515_1104244_-	bifunctional 3-demethylubiquinone 3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase	NA	NA	NA	NA
WP_002210821.1\|1104505_1107181_+	DNA topoisomerase (ATP-hydrolyzing) subunit A	G3M9Z5	Bacillus_virus	4.0e-102	34.4
WP_002228028.1\|1107368_1110242_+	two-component system sensor histidine kinase RcsC	A0A1V0SGX0	Hokovirus	3.8e-42	28.3
WP_002210824.1\|1110309_1110963_-	transcriptional regulator RcsB	NA	NA	NA	NA
WP_002216094.1\|1110965_1111538_-	Hpt domain-containing protein	NA	NA	NA	NA
WP_002216093.1\|1111705_1113658_-	phosphotransferase RcsD	NA	NA	NA	NA
WP_002210825.1\|1113681_1114836_-	MFS transporter	NA	NA	NA	NA
WP_002210826.1\|1115938_1117054_+	porin OmpC	Q1MVN1	Enterobacteria_phage	9.6e-111	57.6
WP_002213775.1\|1117255_1117714_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002213759.1\|1117966_1118425_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002228026.1\|1119214_1120381_-	D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH	NA	NA	NA	NA
WP_002208870.1\|1120655_1122182_-	MFS transporter	NA	NA	NA	NA
WP_002208869.1\|1122558_1123587_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_002208868.1\|1123660_1125448_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.0e-10	63.5
WP_002208867.1\|1125869_1126805_-	omptin family outer membrane beta-barrel protein YcoA	NA	NA	NA	NA
WP_002208866.1\|1126976_1127219_-	DinI family protein	K7PKR6	Enterobacteria_phage	6.9e-22	65.0
WP_002208864.1\|1127424_1128147_-	LexA family transcriptional regulator	F1C599	Cronobacter_phage	2.2e-63	51.9
WP_002215470.1\|1128420_1128900_+	antitermination protein Q	S5M7R9	Escherichia_phage	2.3e-37	61.0
WP_002208862.1\|1129110_1130415_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	1.7e-90	46.0
WP_002208861.1\|1131123_1131936_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002208860.1\|1131911_1132706_+	hydroxypyruvate isomerase family protein	NA	NA	NA	NA
WP_002208859.1\|1133319_1133610_+	hypothetical protein	H6WRZ3	Salmonella_phage	7.7e-12	46.3
WP_002208858.1\|1133655_1134273_+	ATP-binding protein	NA	NA	NA	NA
WP_002208857.1\|1134277_1134472_+	DUF2635 domain-containing protein	B5TK66	Pseudomonas_phage	3.5e-08	60.4
WP_002208856.1\|1134468_1135977_+\|tail	phage tail sheath subtilisin-like domain-containing protein	B5TK67	Pseudomonas_phage	2.4e-104	44.2
WP_002208855.1\|1135998_1136367_+\|tail	phage tail tube protein	NA	NA	NA	NA
WP_002208854.1\|1136368_1136668_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_002208853.1\|1136788_1138282_+\|coat	coat protein	NA	NA	NA	NA
WP_002208852.1\|1138548_1139955_+	DNA circularization protein	Q8SBG8	Shigella_phage	2.1e-17	33.7
WP_002208850.1\|1139951_1141007_+\|tail	tail protein	M1PVV2	Vibrio_phage	1.3e-37	27.2
WP_002208848.1\|1141614_1142070_+	phage GP46 family protein	A0A0C4UR04	Shigella_phage	4.3e-17	43.8
WP_002208847.1\|1142073_1143210_+\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	4.5e-31	30.5
WP_002215458.1\|1143206_1143467_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_002208846.1\|1143463_1143811_+	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	6.4e-21	41.3
WP_002208845.1\|1143907_1144687_+\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	7.1e-52	52.4
WP_002208843.1\|1144984_1145725_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002208842.1\|1146015_1147452_+	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_002208841.1\|1147577_1147940_-	hypothetical protein	NA	NA	NA	NA
WP_002208840.1\|1148639_1149128_-	hypothetical protein	NA	NA	NA	NA
WP_002208839.1\|1149140_1150289_-	HNH endonuclease	NA	NA	NA	NA
WP_002230704.1\|1150645_1151029_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	7.8e-36	66.7
WP_002208837.1\|1151259_1153056_-	DUF3413 domain-containing protein	NA	NA	NA	NA
WP_002208836.1\|1153083_1153311_-	YejL family protein	NA	NA	NA	NA
WP_002208835.1\|1153488_1154493_+	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	3.1e-84	47.7
WP_002213775.1\|1154693_1155152_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1

DBSCAN-SWA_6

1266665 : 1276302

Planktothrix_phage(16.67%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211351.1\|1266665_1268615_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	8.8e-35	37.7
WP_002211350.1\|1268895_1269159_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	3.6e-16	59.7
WP_002211349.1\|1269519_1269840_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	8.2e-15	42.7
WP_002211348.1\|1269865_1272142_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	7.4e-166	41.7
WP_002213759.1\|1272434_1272893_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002211347.1\|1273264_1273483_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_002211346.1\|1273648_1274359_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_002211344.1\|1274577_1276302_-	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	3.3e-17	31.8

DBSCAN-SWA_7

1320216 : 1394355

Clostridium_phage(23.08%)

protease,transposase,plate,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211311.1\|1320216_1321002_+\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_002211310.1\|1320998_1322321_+	chromosome partition protein MukF	NA	NA	NA	NA
WP_002211309.1\|1322301_1323030_+	chromosome partition protein MukE	NA	NA	NA	NA
WP_002211308.1\|1323026_1327484_+	chromosome partition protein MukB	NA	NA	NA	NA
WP_002213759.1\|1327699_1328158_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002217987.1\|1328441_1330298_+	L,D-transpeptidase	NA	NA	NA	NA
WP_002211305.1\|1330521_1331070_+	YcbK family protein	A0A0K1LLY2	Rhodobacter_phage	7.8e-05	34.7
WP_002211304.1\|1331130_1331778_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	2.2e-22	32.3
WP_002430096.1\|1331931_1332048_-	hypothetical protein	NA	NA	NA	NA
WP_002211303.1\|1332201_1333392_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_002354007.1\|1333648_1334728_-	porin OmpF	Q1MVN1	Enterobacteria_phage	3.2e-111	56.5
WP_002211301.1\|1335028_1336429_-\|tRNA	asparagine--tRNA ligase	A0A167RLM0	Powai_lake_megavirus	6.5e-80	35.2
WP_002228013.1\|1336927_1338133_-	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_002220013.1\|1338848_1341464_+	aminopeptidase N	NA	NA	NA	NA
WP_002211296.1\|1342081_1343092_+	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_002211295.1\|1343274_1343826_+	cell division protein ZapC	NA	NA	NA	NA
WP_002211294.1\|1343851_1344964_-	MOSC N-terminal beta barrel domain-containing protein	NA	NA	NA	NA
WP_002211293.1\|1345063_1347184_+	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_002211292.1\|1347189_1349103_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	1.5e-47	28.9
WP_002211291.1\|1349231_1350518_+	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_002211290.1\|1350504_1352157_+	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_002211289.1\|1352153_1352732_+	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_002228015.1\|1353001_1353169_+	ribosome modulation factor	NA	NA	NA	NA
WP_002213775.1\|1353366_1353825_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_001297096.1\|1354985_1355765_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1355764_1356787_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211286.1\|1357420_1357609_+	hypothetical protein	NA	NA	NA	NA
WP_002220006.1\|1357874_1358393_-	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_002224683.1\|1358461_1360213_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_002226586.1\|1360423_1360879_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_002213775.1\|1361047_1361506_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002213066.1\|1361695_1362757_-	porin OmpA	NA	NA	NA	NA
WP_002213065.1\|1363114_1363621_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_002213064.1\|1363849_1364485_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_002213063.1\|1364586_1366725_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_002213062.1\|1366754_1367201_-	YccF domain-containing protein	NA	NA	NA	NA
WP_002213061.1\|1367394_1369380_+	DNA helicase IV	A7KV33	Bacillus_phage	5.3e-19	28.4
WP_002213060.1\|1369440_1369905_-	methylglyoxal synthase	NA	NA	NA	NA
WP_002213058.1\|1370083_1370764_-	DUF2057 family protein	NA	NA	NA	NA
WP_002213056.1\|1371079_1371496_+	CoA-binding protein	NA	NA	NA	NA
WP_002213054.1\|1371604_1371922_-	heat shock protein HspQ	NA	NA	NA	NA
WP_002213052.1\|1371982_1373173_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	W6LLI2	Streptococcus_phage	2.1e-26	28.1
WP_002213049.1\|1373266_1373545_+	acylphosphatase	NA	NA	NA	NA
WP_002213046.1\|1373596_1373926_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_002213039.1\|1377571_1379989_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002213038.1\|1380142_1380889_-	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.3e-14	31.4
WP_002213036.1\|1381619_1381838_+	hypothetical protein	NA	NA	NA	NA
WP_002213034.1\|1382101_1382626_+	beta-hydroxyacyl-ACP dehydratase	NA	NA	NA	NA
WP_002213032.1\|1382615_1383899_+	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	NA	NA	NA	NA
WP_002213030.1\|1383900_1384638_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002213028.1\|1384653_1385892_+	hydroxymethylglutaryl-CoA synthase family protein	NA	NA	NA	NA
WP_002213026.1\|1385884_1386604_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213025.1\|1386605_1387358_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213024.1\|1387360_1388149_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002228570.1\|1388235_1388676_+	lipocalin-like domain-containing protein	NA	NA	NA	NA
WP_002213017.1\|1388713_1388962_+	acyl carrier protein	NA	NA	NA	NA
WP_002213016.1\|1389060_1389909_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_002213014.1\|1390897_1391398_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002214707.1\|1391440_1392991_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002213011.1\|1393002_1394355_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_8

1419219 : 1468657

Escherichia_phage(18.18%)

tRNA,transposase,lysis,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211940.1\|1419219_1420983_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002211941.1\|1420946_1422032_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002214552.1\|1422006_1422588_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211943.1\|1422587_1423040_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002211944.1\|1423064_1424432_+	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_002211945.1\|1424643_1425267_-	hypothetical protein	NA	NA	NA	NA
WP_002227996.1\|1425949_1427545_+	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	6.1e-58	28.5
WP_002211947.1\|1427772_1428426_+	hypothetical protein	NA	NA	NA	NA
WP_002209743.1\|1428469_1429678_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211948.1\|1429813_1430584_-	molybdopterin-synthase adenylyltransferase MoeB	NA	NA	NA	NA
WP_002211949.1\|1430585_1431860_-	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_002211950.1\|1432394_1433705_-	darobactin maturation radical SAM/SPASM protein DarE	NA	NA	NA	NA
WP_002211951.1\|1433714_1434383_-	darobactin export ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-35	40.0
WP_002211952.1\|1434384_1435647_-	darobactin export ABC transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_002215886.1\|1435648_1438009_-	darobactin export ABC transporter permease subunit	NA	NA	NA	NA
WP_002227980.1\|1438092_1438305_-	peptide antibiotic darobactin C	NA	NA	NA	NA
WP_002211956.1\|1438561_1439404_-	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_002211957.1\|1439424_1440564_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	5.2e-35	29.9
WP_002211958.1\|1440836_1441706_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211959.1\|1441841_1442993_+	YbfB/YjiJ family MFS transporter	NA	NA	NA	NA
WP_002211960.1\|1443176_1443839_+	GTP cyclohydrolase I FolE	R9TJA5	Vibrio_phage	5.8e-55	53.5
WP_002211961.1\|1443893_1445060_+	DUF418 family protein	NA	NA	NA	NA
WP_002215885.1\|1445807_1446815_+	galactose/glucose ABC transporter substrate-binding protein MglB	NA	NA	NA	NA
WP_002211965.1\|1448584_1449595_+	galactose/methyl galactoside ABC transporter permease MglC	NA	NA	NA	NA
WP_002211966.1\|1450039_1450777_-	outer membrane permeability protein SanA	NA	NA	NA	NA
WP_002211968.1\|1451057_1452755_-	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_002211969.1\|1453109_1453994_-	cytidine deaminase	NA	NA	NA	NA
WP_002211970.1\|1454319_1455015_-\|lysis	CidB/LrgB family autolysis modulator	NA	NA	NA	NA
WP_002211971.1\|1455011_1455419_-	CidA/LrgA family protein	NA	NA	NA	NA
WP_002211973.1\|1455660_1456842_-	MFS transporter	NA	NA	NA	NA
WP_002211974.1\|1457174_1458428_-	LVIVD repeat-containing protein	NA	NA	NA	NA
WP_002211975.1\|1458445_1459522_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002228565.1\|1460219_1460882_+	hypothetical protein	NA	NA	NA	NA
WP_001297096.1\|1461146_1461926_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1461925_1462948_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002213775.1\|1463058_1463517_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002211870.1\|1463680_1465708_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	8.0e-55	27.1
WP_002211871.1\|1465972_1467085_+	iron-sulfur cluster carrier protein ApbC	NA	NA	NA	NA
WP_002211872.1\|1467329_1467971_+	uridine kinase	A0A1V0SAA3	Catovirus	1.0e-35	37.9
WP_002211873.1\|1468075_1468657_+	dCTP deaminase	I4AZP2	Saccharomonospora_phage	2.5e-33	43.2

DBSCAN-SWA_9

1512230 : 1568127

uncultured_virus(27.27%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002209743.1\|1512230_1513439_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002216388.1\|1513401_1516554_-	inverse autotransporter beta-barrel domain-containing protein	NA	NA	NA	NA
WP_002211911.1\|1517578_1518883_+	MFS transporter	NA	NA	NA	NA
WP_002211912.1\|1518891_1519314_-	thiol-disulfide oxidoreductase DCC family protein	NA	NA	NA	NA
WP_002216393.1\|1519741_1520482_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002211916.1\|1520529_1521372_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_002211917.1\|1521403_1522681_+	L-fuconate dehydratase	NA	NA	NA	NA
WP_002211919.1\|1522977_1524123_+	FMN-dependent L-lactate dehydrogenase LldD	NA	NA	NA	NA
WP_002211920.1\|1524327_1525695_-	argininosuccinate synthase	A0A140XAJ5	Dickeya_phage	7.0e-63	93.7
WP_002224723.1\|1525988_1527419_+	EmmdR/YeeO family multidrug/toxin efflux MATE transporter	NA	NA	NA	NA
WP_002211922.1\|1527446_1528787_-	MFS transporter	NA	NA	NA	NA
WP_002211923.1\|1528822_1529704_-	polysaccharide deacetylase	NA	NA	NA	NA
WP_002217591.1\|1530280_1530976_+	hypothetical protein	NA	NA	NA	NA
WP_002211926.1\|1531065_1531605_+	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_002213125.1\|1532471_1533101_-	response regulator transcription factor	NA	NA	NA	NA
WP_002213124.1\|1533358_1534651_-	TRAP transporter large permease	NA	NA	NA	NA
WP_002213122.1\|1534670_1535177_-	TRAP transporter small permease	NA	NA	NA	NA
WP_002213121.1\|1535300_1536293_-	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_002213120.1\|1536815_1537556_+	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_002216586.1\|1537761_1537926_-	hypothetical protein	NA	NA	NA	NA
WP_002213113.1\|1537942_1540069_-	alpha-galactosidase	NA	NA	NA	NA
WP_042468818.1\|1540146_1541424_-	MFS transporter	NA	NA	NA	NA
WP_002209743.1\|1541448_1542657_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002217041.1\|1542619_1542916_-	biofilm formation regulator BssS	NA	NA	NA	NA
WP_002213110.1\|1543421_1543667_-	DNA damage-inducible protein I	K7PM44	Enterobacteria_phage	2.6e-13	51.3
WP_002213109.1\|1543979_1545026_-	dihydroorotase	NA	NA	NA	NA
WP_002213107.1\|1545260_1545548_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_002209743.1\|1545824_1547033_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002354074.1\|1547128_1550785_-	ribonuclease E	NA	NA	NA	NA
WP_002210927.1\|1551368_1552331_+	23S rRNA pseudouridine(955/2504/2580) synthase RluC	NA	NA	NA	NA
WP_002213759.1\|1552550_1553009_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002210928.1\|1553163_1553760_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_002210930.1\|1553901_1554426_+	23S rRNA accumulation protein YceD	NA	NA	NA	NA
WP_002210931.1\|1554438_1554606_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_002210932.1\|1554639_1555674_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_002210933.1\|1555680_1556631_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_002210934.1\|1556668_1557598_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_002210935.1\|1557611_1558346_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	7.7e-16	33.1
WP_002220787.1\|1558499_1558736_+	acyl carrier protein	B2ZXV3	Ralstonia_phage	7.7e-10	45.6
WP_002213079.1\|1558830_1560072_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_002213775.1\|1560271_1560730_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002213080.1\|1561145_1561952_+	aminodeoxychorismate lyase	NA	NA	NA	NA
WP_002217396.1\|1562240_1563266_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_002213082.1\|1563255_1563894_+	dTMP kinase	Q2Z0N0	Pseudomonas_phage	4.6e-25	36.1
WP_002213083.1\|1563893_1564916_+	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_002213084.1\|1564930_1565740_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_002213085.1\|1566045_1567479_+	PTS glucose transporter subunit IIBC	NA	NA	NA	NA
WP_002213759.1\|1567668_1568127_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1

DBSCAN-SWA_10

1664095 : 1682083

Escherichia_phage(50.0%)

protease,coat,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|1664095_1665118_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002215943.1\|1665524_1665914_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_002210859.1\|1666023_1666263_-	YebV family protein	NA	NA	NA	NA
WP_002210858.1\|1666470_1667460_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_002210857.1\|1667665_1670113_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002210856.1\|1670300_1671053_-	molecular chaperone	NA	NA	NA	NA
WP_002216611.1\|1671083_1671641_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216613.1\|1671661_1672192_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002210852.1\|1672197_1672752_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216616.1\|1673230_1675882_-	PqiB family protein	NA	NA	NA	NA
WP_002367629.1\|1675850_1677098_-	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_002210850.1\|1677329_1677827_+	GAF domain-containing protein	NA	NA	NA	NA
WP_002210849.1\|1677922_1678636_+	RNA chaperone ProQ	NA	NA	NA	NA
WP_002210848.1\|1678655_1680728_+	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	4.0e-86	34.8
WP_002210847.1\|1681201_1682083_+\|protease	protease HtpX	NA	NA	NA	NA

DBSCAN-SWA_11

1984055 : 2083712

104

Escherichia_phage(14.81%)

tRNA,holin,lysis,integrase,tail,transposase

attL 1994607:1994637|attR 2036331:2036361

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211184.1\|1984055_1984754_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_002211183.1\|1984890_1985496_+	Slp family lipoprotein	NA	NA	NA	NA
WP_087768167.1\|1985496_1985604_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002211182.1\|1986138_1987827_+	long-chain-fatty-acid--CoA ligase FadD	A0A2H4PQM9	Staphylococcus_phage	1.8e-31	28.9
WP_002211181.1\|1987986_1989108_+	ribonuclease D	NA	NA	NA	NA
WP_002211180.1\|1989344_1989614_-	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_002211179.1\|1989617_1990430_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_002220631.1\|1990454_1991141_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_002211743.1\|1991861_1992134_+	YcgL domain-containing protein	NA	NA	NA	NA
WP_002215627.1\|1992274_1993360_+	lytic murein transglycosylase	NA	NA	NA	NA
WP_002211740.1\|1993430_1994087_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_002211739.1\|1994189_1994636_+	YcgN family cysteine cluster protein	NA	NA	NA	NA
1994607:1994637	attL	NA	NA	NA	NA
WP_002211738.1\|1994662_1995901_-\|integrase	site-specific integrase	Q20GI2	Phage_258-320	2.3e-121	53.3
WP_000255944.1\|1995970_1996993_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1996992_1997772_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002215632.1\|1997939_1998200_-	excisionase family protein	Q859D3	Escherichia_coli_phage	1.7e-10	42.9
WP_002211736.1\|1999224_1999671_+	recombination protein NinB	A0A2H4J8D9	uncultured_Caudovirales_phage	3.9e-47	62.5
WP_002211735.1\|1999744_2000350_+	recombination protein NinG	A0A1P8DTE0	Proteus_phage	2.8e-56	56.9
WP_002215636.1\|2000350_2000740_+	antitermination protein	A0A1W6JNX1	Morganella_phage	1.4e-45	68.8
WP_002215638.1\|2000743_2000962_+	ash family protein	NA	NA	NA	NA
WP_002211732.1\|2001010_2001574_+	Bro-N domain-containing protein	B6SD63	Bacteriophage	9.4e-30	58.0
WP_002393183.1\|2001658_2001835_-	hypothetical protein	NA	NA	NA	NA
WP_002211731.1\|2001997_2002207_+	hypothetical protein	NA	NA	NA	NA
WP_002215644.1\|2002203_2002479_-	hypothetical protein	NA	NA	NA	NA
WP_002430108.1\|2002724_2002922_+\|holin	phage holin family protein	B6SD15	Bacteriophage	4.9e-18	64.4
WP_002211730.1\|2002952_2003465_+	lysozyme	I6PBN2	Cronobacter_phage	9.7e-50	61.6
WP_002211729.1\|2003449_2003908_+\|lysis	lysis protein	A0A2H4JHL8	uncultured_Caudovirales_phage	4.9e-21	45.3
WP_002211727.1\|2004453_2005167_+	phage antirepressor KilAC domain-containing protein	Q5MBW0	Stx1-converting_phage	7.6e-69	60.2
WP_002211725.1\|2005623_2006259_+	hypothetical protein	I6S676	Salmonella_phage	7.2e-87	71.4
WP_002211724.1\|2006289_2006739_+	DUF2280 domain-containing protein	I6S1P9	Salmonella_phage	1.0e-47	72.9
WP_002211723.1\|2006742_2007327_+	hypothetical protein	A0A0R6PHH0	Moraxella_phage	4.8e-69	70.7
WP_002209743.1\|2007374_2008583_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211722.1\|2008587_2009562_+	hypothetical protein	A0A1W6JNY3	Morganella_phage	2.3e-153	81.1
WP_002228445.1\|2009561_2010290_+	hypothetical protein	A0A1B0VMH0	Pseudomonas_phage	4.6e-61	51.4
WP_002228446.1\|2010308_2010950_+	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	3.8e-59	54.1
WP_002211721.1\|2010950_2012063_+	hypothetical protein	I6PD76	Cronobacter_phage	6.0e-121	58.2
WP_002211720.1\|2012184_2012958_+	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	2.8e-69	62.3
WP_002211719.1\|2012971_2014177_+	Ig-like domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	1.8e-142	79.2
WP_002211718.1\|2014224_2014707_+	hypothetical protein	G8C7P9	Escherichia_phage	6.4e-27	46.1
WP_002211717.1\|2014703_2014958_+	hypothetical protein	J9Q7U0	Salmonella_phage	2.2e-18	53.1
WP_002211716.1\|2014959_2015310_+	hypothetical protein	I6PD77	Cronobacter_phage	6.9e-31	56.0
WP_002211715.1\|2015311_2015896_+	hypothetical protein	G8C7Q1	Escherichia_phage	3.6e-48	52.1
WP_002211714.1\|2015892_2016300_+	DUF4128 domain-containing protein	NA	NA	NA	NA
WP_002211713.1\|2016365_2017286_+	Ig-like domain-containing protein	I6PBN6	Cronobacter_phage	4.4e-61	49.1
WP_002211712.1\|2017298_2017610_+	hypothetical protein	I6PDG2	Cronobacter_phage	1.4e-30	58.3
WP_071525538.1\|2017657_2017918_+	DUF1799 domain-containing protein	A0A0S2SY90	Pseudomonas_phage	3.7e-13	50.0
WP_002211711.1\|2017918_2021422_+\|tail	phage tail tape measure protein	K7PMB9	Enterobacterial_phage	5.2e-118	33.2
WP_002211710.1\|2021424_2021766_+\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	1.7e-21	50.0
WP_002213759.1\|2022070_2022529_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002211709.1\|2022649_2023402_+\|tail	phage minor tail protein L	A0A1W6JNX9	Morganella_phage	9.4e-102	67.7
WP_002211708.1\|2023404_2024115_+	C40 family peptidase	K7P6F5	Enterobacteria_phage	1.3e-108	76.8
WP_002211707.1\|2024375_2025008_+	hypothetical protein	NA	NA	NA	NA
WP_002211706.1\|2025086_2025518_-	Arc family DNA-binding protein	G9L6D6	Escherichia_phage	2.5e-30	58.4
WP_002211705.1\|2025641_2025809_+	hypothetical protein	G9L6D7	Escherichia_phage	5.2e-13	61.8
WP_002211704.1\|2025882_2026890_+	Bro-N domain-containing protein	A0A2H4J0P1	uncultured_Caudovirales_phage	4.1e-36	33.0
WP_002214482.1\|2026988_2027540_+	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	9.5e-27	58.0
WP_002211701.1\|2027682_2027898_+	hypothetical protein	NA	NA	NA	NA
WP_002211700.1\|2027953_2028574_+\|tail	tail assembly protein	K7PGY0	Enterobacteria_phage	3.2e-55	57.0
WP_002211699.1\|2028615_2028780_+	hypothetical protein	NA	NA	NA	NA
WP_002359202.1\|2028748_2028970_-	hypothetical protein	NA	NA	NA	NA
WP_002211698.1\|2029145_2032349_+	host specificity protein J	F1C571	Cronobacter_phage	0.0e+00	60.5
WP_002211697.1\|2032348_2033347_+	hypothetical protein	NA	NA	NA	NA
WP_002211696.1\|2033363_2034281_+	hypothetical protein	NA	NA	NA	NA
WP_002211695.1\|2034291_2034711_+\|tail	tail fiber assembly protein	B6SCW7	Bacteriophage	5.7e-08	42.0
WP_002209743.1\|2034931_2036140_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002214492.1\|2036444_2037617_-	MFS transporter	NA	NA	NA	NA
2036331:2036361	attR	NA	NA	NA	NA
WP_002211693.1\|2037620_2038820_-	cysteine desulfurase	A0A1X7QGF3	Faustovirus	2.4e-38	29.6
WP_002211692.1\|2038836_2039577_-	hypothetical protein	NA	NA	NA	NA
WP_002214494.1\|2040668_2041025_+	hypothetical protein	NA	NA	NA	NA
WP_002227934.1\|2041441_2041972_-	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_002211689.1\|2042207_2043782_-	sodium/proton antiporter NhaB	NA	NA	NA	NA
WP_002211688.1\|2044025_2044745_+	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_002211687.1\|2044962_2046498_-	SpoVR family protein	NA	NA	NA	NA
WP_002211686.1\|2046962_2048267_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_002216508.1\|2048282_2049485_-	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	7.6e-29	29.1
WP_002211685.1\|2049749_2050619_-	pirin family protein	NA	NA	NA	NA
WP_002211684.1\|2050816_2051722_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211683.1\|2051756_2052875_-	DMT family transporter	NA	NA	NA	NA
WP_002216501.1\|2052982_2054257_-	YeaH/YhbH family protein	A0A140HLI1	Bacillus_phage	1.5e-11	37.1
WP_002211681.1\|2054406_2056341_-	protein kinase YeaG	NA	NA	NA	NA
WP_002430110.1\|2056784_2057534_+	MipA/OmpV family protein	NA	NA	NA	NA
WP_002211679.1\|2057606_2058482_-	D-hexose-6-phosphate mutarotase	NA	NA	NA	NA
WP_002224141.1\|2058795_2059791_-	glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_002211677.1\|2060138_2060552_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_002217933.1\|2060622_2060895_+	YeaC family protein	NA	NA	NA	NA
WP_002211676.1\|2061028_2061676_-	bifunctional nicotinamidase/pyrazinamidase	A0A2K9L6K4	Tupanvirus	1.8e-21	33.0
WP_002211675.1\|2061690_2062707_-	asparaginase	NA	NA	NA	NA
WP_002211674.1\|2062823_2064674_-	signal peptide peptidase SppA	NA	NA	NA	NA
WP_002211673.1\|2064836_2065388_+	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_002211671.1\|2065612_2066659_+	selenide, water dikinase SelD	NA	NA	NA	NA
WP_002211670.1\|2066720_2068646_+	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.2e-37	30.4
WP_002211669.1\|2068642_2068933_+	DUF1496 domain-containing protein	NA	NA	NA	NA
WP_002211668.1\|2068945_2069332_-	pyrimidine (deoxy)nucleoside triphosphate diphosphatase	NA	NA	NA	NA
WP_002211667.1\|2069429_2070236_-	exodeoxyribonuclease III	NA	NA	NA	NA
WP_002211665.1\|2071045_2071906_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002209743.1\|2072777_2073986_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002210667.1\|2073948_2074818_-	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	5.5e-13	37.3
WP_002210666.1\|2074901_2075366_-	YchJ family protein	NA	NA	NA	NA
WP_002210665.1\|2076699_2077716_+	two-component system response regulator RssB	NA	NA	NA	NA
WP_002210664.1\|2078022_2079369_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.9e-81	38.3
WP_002210661.1\|2079803_2080202_-	DNA-binding transcriptional regulator H-NS	NA	NA	NA	NA
WP_002210659.1\|2080951_2081542_+	thymidine kinase	A0A1Z1LYD5	Serratia_phage	1.5e-54	55.8
WP_001297096.1\|2081910_2082690_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|2082689_2083712_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_12

2740744 : 2795994

Clostridium_phage(18.18%)

tRNA,integrase,transposase

attL 2740637:2740696|attR 2795428:2796139

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2740637:2740696	attL	NA	NA	NA	NA
WP_002213775.1\|2740744_2741203_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002209726.1\|2741481_2742492_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_002209727.1\|2742491_2743373_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_002209728.1\|2743529_2744192_+	DedA family protein	NA	NA	NA	NA
WP_002209729.1\|2744422_2745337_+	acetyl-CoA carboxylase, carboxyltransferase subunit beta	NA	NA	NA	NA
WP_002209730.1\|2745585_2746890_+	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_002209731.1\|2747009_2747732_+	cell division protein DedD	NA	NA	NA	NA
WP_002209732.1\|2748043_2748553_+	colicin V production protein	NA	NA	NA	NA
WP_002209733.1\|2748565_2750083_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.0e-86	42.4
WP_002209734.1\|2750329_2750902_+	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_002216029.1\|2751426_2752209_+	histidine ABC transporter substrate-binding protein HisJ	NA	NA	NA	NA
WP_002209736.1\|2752311_2752998_+	histidine ABC transporter permease HisQ	NA	NA	NA	NA
WP_002209737.1\|2752994_2753711_+	ABC transporter permease	NA	NA	NA	NA
WP_002209738.1\|2753724_2754522_+	histidine ABC transporter ATP-binding protein HisP	G9BWD6	Planktothrix_phage	7.1e-23	33.5
WP_002209739.1\|2754645_2755554_-	TIGR01777 family protein	NA	NA	NA	NA
WP_002209740.1\|2755907_2756600_+	EAL domain-containing protein	NA	NA	NA	NA
WP_002227850.1\|2756800_2757376_+	phosphodiesterase	NA	NA	NA	NA
WP_002209742.1\|2757597_2758146_+	NUDIX hydrolase YfcD	NA	NA	NA	NA
WP_002222248.1\|2758262_2759519_-	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_002209743.1\|2759658_2760867_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_071525544.1\|2760930_2762433_+	penicillin-binding protein 1C	NA	NA	NA	NA
WP_002209745.1\|2762645_2762891_-	helix-turn-helix domain-containing protein	A0A2I7S995	Vibrio_phage	7.2e-19	64.2
WP_002209746.1\|2764412_2764814_+	DUF1240 domain-containing protein	NA	NA	NA	NA
WP_002209748.1\|2765046_2765448_+	DUF1240 domain-containing protein	NA	NA	NA	NA
WP_002209749.1\|2765459_2766032_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002227852.1\|2766055_2766307_-	hypothetical protein	NA	NA	NA	NA
WP_002209751.1\|2766345_2766585_-	hypothetical protein	NA	NA	NA	NA
WP_002209752.1\|2767393_2769310_+	autotransporter adhesin YapC	NA	NA	NA	NA
WP_002224869.1\|2769433_2769556_+	hypothetical protein	NA	NA	NA	NA
WP_002209753.1\|2769844_2770426_+	AbiEi antitoxin N-terminal domain-containing protein	NA	NA	NA	NA
WP_002209743.1\|2770827_2772036_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002209756.1\|2772487_2774695_+	DUF4401 domain-containing protein	NA	NA	NA	NA
WP_002209757.1\|2774687_2775218_+	GDYXXLXY domain-containing protein	NA	NA	NA	NA
WP_002209758.1\|2775376_2777758_+	glycoside hydrolase family 3 C-terminal domain-containing protein	NA	NA	NA	NA
WP_002209759.1\|2777836_2779465_-	hypothetical protein	NA	NA	NA	NA
WP_002209762.1\|2779937_2780789_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-49	41.1
WP_002209763.1\|2780814_2781804_+	aldo/keto reductase	NA	NA	NA	NA
WP_002209764.1\|2781858_2782752_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000255944.1\|2782845_2783868_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002215253.1\|2785012_2785318_-	hypothetical protein	NA	NA	NA	NA
WP_002209765.1\|2785414_2785816_-	hypothetical protein	NA	NA	NA	NA
WP_002209766.1\|2785797_2787117_-	phosphatase PAP2/dual specificity phosphatase family protein	NA	NA	NA	NA
WP_002215255.1\|2787109_2788873_-	bifunctional alpha/beta hydrolase/class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002209768.1\|2788869_2789502_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_002209769.1\|2789511_2790441_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_002209770.1\|2790433_2791036_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_002354559.1\|2791435_2791642_-	hypothetical protein	NA	NA	NA	NA
WP_079866998.1\|2791853_2792132_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y6Q1	Salmonella_phage	4.2e-31	73.5
WP_002215266.1\|2792214_2792553_+	hypothetical protein	NA	NA	NA	NA
WP_002228356.1\|2792688_2793186_+	hypothetical protein	NA	NA	NA	NA
WP_002215268.1\|2793299_2793500_+	hypothetical protein	NA	NA	NA	NA
WP_002215270.1\|2793758_2793941_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_002209774.1\|2794295_2795162_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.2e-30	34.1
WP_002209775.1\|2795176_2795389_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_002213775.1\|2795535_2795994_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
2795428:2796139	attR	NA	NA	NA	NA

DBSCAN-SWA_13

2860338 : 2928102

Clostridium_phage(14.29%)

transposase,plate,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002209820.1\|2860338_2861535_-\|tRNA	bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN	NA	NA	NA	NA
WP_002209821.1\|2861796_2862225_-	nucleoside-diphosphate kinase	A0A167REB2	Powai_lake_megavirus	1.1e-17	39.4
WP_002215515.1\|2862551_2864972_-	peptidase inhibitor family I36 protein	NA	NA	NA	NA
WP_146737630.1\|2865661_2870050_+	autotransporter YapA	NA	NA	NA	NA
WP_002215508.1\|2870607_2873766_+	autotransporter outer membrane beta-barrel domain-containing protein	NA	NA	NA	NA
WP_002215505.1\|2873731_2874052_+	autotransporter outer membrane beta-barrel domain-containing protein	NA	NA	NA	NA
WP_071525548.1\|2874130_2874256_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002209828.1\|2874389_2875343_-	enhanced serine sensitivity protein SseB	NA	NA	NA	NA
WP_002209829.1\|2875421_2876720_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	9.7e-38	39.0
WP_002209830.1\|2876859_2877060_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_002209831.1\|2877089_2877425_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_002209832.1\|2877427_2879380_-	Fe-S protein assembly chaperone HscA	F2Y2E1	Organic_Lake_phycodnavirus	1.8e-96	37.8
WP_002209833.1\|2879622_2880147_-	co-chaperone HscB	NA	NA	NA	NA
WP_002209834.1\|2880257_2880581_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	7.8e-21	47.7
WP_002209835.1\|2880850_2881237_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	77.3
WP_002209836.1\|2881267_2882497_-	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	8.6e-36	33.1
WP_002222202.1\|2882550_2883045_-	Fe-S cluster assembly transcriptional regulator IscR	NA	NA	NA	NA
WP_002217034.1\|2883200_2883974_-\|tRNA	tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ	NA	NA	NA	NA
WP_002213305.1\|2884092_2884896_+	inositol-1-monophosphatase	NA	NA	NA	NA
WP_002213775.1\|2885099_2885558_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002217028.1\|2885704_2886727_-	nickel/cobalt transporter	NA	NA	NA	NA
WP_002213310.1\|2886717_2887392_-	DUF1007 family protein	NA	NA	NA	NA
WP_002213314.1\|2887533_2888895_+	stationary phase inducible protein CsiE	NA	NA	NA	NA
WP_002213316.1\|2888891_2890049_-	3-phenylpropionate MFS transporter	NA	NA	NA	NA
WP_002227864.1\|2890400_2890949_-	attachment invasion locus protein Ail	A0A1B0VBR9	Salmonella_phage	6.8e-25	36.7
WP_002223388.1\|2891058_2891241_-	hypothetical protein	NA	NA	NA	NA
WP_002211552.1\|2891392_2892646_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	2.8e-98	52.5
WP_002211553.1\|2893186_2894377_+	NO-inducible flavohemoprotein	NA	NA	NA	NA
WP_002211554.1\|2895909_2896248_-	nitrogen regulatory protein P-II	NA	NA	NA	NA
WP_002211555.1\|2896262_2897885_-	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	1.1e-94	36.5
WP_002211556.1\|2898044_2899382_-	two-component system response regulator GlrR	W8CYM9	Bacillus_phage	1.2e-11	37.4
WP_072120864.1\|2899344_2900367_-	two-component system QseEF-associated lipoprotein QseG	NA	NA	NA	NA
WP_002216114.1\|2900415_2901852_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	3.1e-13	23.8
WP_002213759.1\|2902072_2902531_-\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002216113.1\|2902520_2902745_-	hypothetical protein	NA	NA	NA	NA
WP_002211559.1\|2903757_2904318_+	hypothetical protein	NA	NA	NA	NA
WP_002211560.1\|2904769_2905219_+	hypothetical protein	NA	NA	NA	NA
WP_032487261.1\|2905526_2905634_+	hypothetical protein	NA	NA	NA	NA
WP_002211561.1\|2905630_2909521_-	phosphoribosylformylglycinamidine synthase	A9YX36	Burkholderia_phage	8.8e-127	59.5
WP_002211562.1\|2909836_2911297_+	membrane-bound lytic murein transglycosylase MltF	I1VXB7	Halocynthia_phage	7.1e-13	41.4
WP_002211563.1\|2911405_2912008_-\|tRNA	tRNA adenosine(34) deaminase TadA	S4VYT2	Pandoravirus	6.5e-05	34.1
WP_002211564.1\|2912078_2912774_-	phosphatidylglycerophosphatase C	NA	NA	NA	NA
WP_002211565.1\|2913000_2913888_-	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
WP_002211566.1\|2914095_2914935_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002211567.1\|2915096_2915357_+	YfhL family 4Fe-4S dicluster ferredoxin	A0A1B1IWY9	uncultured_Mediterranean_phage	9.3e-17	53.5
WP_002213775.1\|2915512_2915971_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002211568.1\|2916172_2916553_-	holo-ACP synthase	NA	NA	NA	NA
WP_002211569.1\|2916552_2917284_-	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_001297096.1\|2917473_2918253_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|2918252_2919275_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211571.1\|2919953_2921303_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002211572.1\|2921306_2921846_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211573.1\|2922119_2922605_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002211574.1\|2922930_2924433_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211575.1\|2924456_2924981_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002211576.1\|2925085_2925694_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002211577.1\|2925678_2926869_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002209743.1\|2926893_2928102_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8

DBSCAN-SWA_14

3267692 : 3321556

Escherichia_phage(33.33%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|3267692_3268715_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3268714_3269494_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002418742.1\|3269544_3270444_-	alanine--glyoxylate aminotransferase family protein	NA	NA	NA	NA
WP_002208732.1\|3270499_3271246_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.4e-35	41.1
WP_002208733.1\|3271226_3271880_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002208734.1\|3271876_3272545_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002208735.1\|3272557_3273346_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_002208736.1\|3273673_3274507_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002208738.1\|3274816_3275020_+	oxalurate catabolism protein HpxX	NA	NA	NA	NA
WP_002208739.1\|3275016_3276414_+	AtzE family amidohydrolase	NA	NA	NA	NA
WP_002264506.1\|3276523_3276910_+	oxalurate catabolism protein HpxZ	NA	NA	NA	NA
WP_002208741.1\|3277143_3278343_+	MFS transporter	NA	NA	NA	NA
WP_002208742.1\|3278502_3279276_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_002208743.1\|3279272_3279614_+	L-valine transporter subunit YgaH	NA	NA	NA	NA
WP_002208744.1\|3279785_3280298_+	transcriptional repressor MprA	NA	NA	NA	NA
WP_002208745.1\|3280681_3281854_+	multidrug efflux MFS transporter periplasmic adaptor subunit EmrA	NA	NA	NA	NA
WP_002208746.1\|3281892_3283428_+	multidrug efflux MFS transporter permease subunit EmrB	NA	NA	NA	NA
WP_002208747.1\|3283550_3284717_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_002216643.1\|3284968_3285406_+	thioredoxin TrxC	A0A1J0GW78	Streptomyces_phage	2.6e-11	36.6
WP_002208749.1\|3285575_3286325_+	DTW domain-containing protein	NA	NA	NA	NA
WP_002208750.1\|3286367_3289010_+	bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002208751.1\|3289185_3290541_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_002208752.1\|3290602_3290944_+	YfiM family lipoprotein	NA	NA	NA	NA
WP_002217405.1\|3297046_3299620_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.4e-128	34.9
WP_002209471.1\|3299749_3300481_-	polyphenol oxidase	NA	NA	NA	NA
WP_002209470.1\|3300482_3301460_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_002209469.1\|3301595_3302327_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_002209468.1\|3302681_3303044_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_002213775.1\|3303374_3303833_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_000255944.1\|3305135_3306158_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3306157_3306937_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002209466.1\|3307013_3307232_+	hypothetical protein	NA	NA	NA	NA
WP_002209465.1\|3307336_3308458_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_002228238.1\|3308470_3309541_-	3-deoxy-7-phosphoheptulonate synthase	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	1.5e-89	51.4
WP_002209463.1\|3309773_3310490_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_002209462.1\|3312585_3313353_+	YdiY family protein	NA	NA	NA	NA
WP_002213759.1\|3313655_3314114_-\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002209461.1\|3314325_3314673_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_002222284.1\|3314753_3315494_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_002209459.1\|3315532_3316081_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_002209458.1\|3316102_3316351_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_002209456.1\|3316578_3317940_-	signal recognition particle protein	NA	NA	NA	NA
WP_002209455.1\|3318105_3318897_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_002354744.1\|3318968_3320249_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_002213759.1\|3320386_3320845_-\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002213775.1\|3321097_3321556_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1

DBSCAN-SWA_15

3590303 : 3642930

Escherichia_phage(17.65%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|3590303_3590762_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002210156.1\|3590957_3591410_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_002210155.1\|3591449_3591677_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_002210154.1\|3591681_3592002_-	primosomal replication protein N	NA	NA	NA	NA
WP_002210153.1\|3592007_3592400_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_002210152.1\|3592766_3593468_-	esterase	NA	NA	NA	NA
WP_000255944.1\|3593524_3594547_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3594546_3595326_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210151.1\|3596406_3597300_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002210150.1\|3597561_3598266_+	pirin family protein	NA	NA	NA	NA
WP_002210149.1\|3599202_3600102_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.0e-49	44.4
WP_002228200.1\|3600164_3602138_+	penicillin-binding protein activator	NA	NA	NA	NA
WP_002210147.1\|3602221_3602575_+	YraN family protein	NA	NA	NA	NA
WP_002210146.1\|3602845_3603436_+	DnaA initiator-associating protein DiaA	A0A067XQR2	Caulobacter_phage	3.2e-12	32.0
WP_002210145.1\|3603446_3604022_+	divisome-associated lipoprotein YraP	NA	NA	NA	NA
WP_002210144.1\|3604228_3604954_-	monofunctional biosynthetic peptidoglycan transglycosylase	NA	NA	NA	NA
WP_002210143.1\|3604950_3605604_-	isoprenoid biosynthesis glyoxalase ElbB	NA	NA	NA	NA
WP_002210142.1\|3605845_3608182_-	aerobic respiration two-component sensor histidine kinase ArcB	A0A1V0SGX0	Hokovirus	9.9e-41	30.4
WP_002210140.1\|3608445_3609369_-	TIGR01212 family radical SAM protein	NA	NA	NA	NA
WP_002229651.1\|3610191_3614658_+	glutamate synthase large subunit	NA	NA	NA	NA
WP_002210138.1\|3614667_3616086_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_002210137.1\|3616526_3617012_+	hypothetical protein	NA	NA	NA	NA
WP_002216203.1\|3617164_3617680_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	3.6e-28	55.6
WP_002210135.1\|3617685_3618327_-	stringent starvation protein A	NA	NA	NA	NA
WP_002230558.1\|3618506_3618704_+	hypothetical protein	NA	NA	NA	NA
WP_002210133.1\|3618700_3619093_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_002210132.1\|3619107_3619536_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_002210131.1\|3619849_3620977_-	cell division protein ZapE	NA	NA	NA	NA
WP_002210130.1\|3621200_3621605_+	DUF1043 family protein	NA	NA	NA	NA
WP_002218066.1\|3621875_3623249_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	7.4e-20	28.2
WP_002213775.1\|3623365_3623824_-\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002210128.1\|3624049_3625138_+	outer membrane-stress sensor serine endopeptidase DegS	A0A1B1IRD3	uncultured_Mediterranean_phage	2.1e-09	31.8
WP_002210127.1\|3625318_3626581_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002210126.1\|3626734_3626989_-	BolA family iron metabolism protein IbaG	NA	NA	NA	NA
WP_002210125.1\|3627135_3627438_-	lipid asymmetry maintenance protein MlaB	NA	NA	NA	NA
WP_002210124.1\|3627473_3628097_-	phospholipid-binding protein MlaC	NA	NA	NA	NA
WP_002210123.1\|3628109_3628667_-	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_002210122.1\|3628671_3629454_-	lipid asymmetry maintenance ABC transporter permease subunit MlaE	NA	NA	NA	NA
WP_002210121.1\|3629671_3630490_-	phospholipid ABC transporter ATP-binding protein MlaF	G3M9Y6	Bacillus_virus	2.2e-19	31.7
WP_002210120.1\|3630754_3631729_+	calcium/sodium antiporter	NA	NA	NA	NA
WP_002210119.1\|3631839_3632826_+	arabinose-5-phosphate isomerase KdsD	A0A2P0VNK5	Tetraselmis_virus	6.0e-40	30.8
WP_002228203.1\|3633074_3633638_+	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	9.6e-59	83.0
WP_002218352.1\|3633634_3634198_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_002210117.1\|3634181_3634727_+	lipopolysaccharide ABC transporter substrate-binding protein LptA	NA	NA	NA	NA
WP_002210116.1\|3634733_3635459_+	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-22	28.4
WP_002210115.1\|3635520_3636954_+	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_002213952.1\|3637382_3637865_+	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_002210113.1\|3638170_3639025_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-05	30.0
WP_002210112.1\|3639021_3639294_+	PTS phosphocarrier protein NPr	NA	NA	NA	NA
WP_002210111.1\|3639631_3640567_+	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.5e-48	38.5
WP_002210110.1\|3640578_3641043_+	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_002210109.1\|3641180_3641567_+	2-iminobutanoate/2-iminopropanoate deaminase	NA	NA	NA	NA
WP_000255944.1\|3641907_3642930_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_16

3772421 : 3856905

Escherichia_phage(28.57%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002212105.1\|3772421_3773768_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002212104.1\|3773770_3774316_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002212103.1\|3774315_3775632_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_002213885.1\|3775757_3776846_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_001297096.1\|3777876_3778656_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|3778655_3779678_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002212100.1\|3782032_3782473_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002212099.1\|3782479_3783961_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002212098.1\|3784028_3784526_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002212097.1\|3785049_3785568_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002212095.1\|3785719_3785998_-	hypothetical protein	NA	NA	NA	NA
WP_002212093.1\|3786468_3787380_-	maltose operon protein MalM	NA	NA	NA	NA
WP_002212092.1\|3787620_3788892_-	maltoporin	NA	NA	NA	NA
WP_002212091.1\|3788962_3790072_-	maltose/maltodextrin ABC transporter ATP-binding protein MalK	G9BWD6	Planktothrix_phage	5.0e-27	35.5
WP_002221973.1\|3790075_3790312_-	hypothetical protein	NA	NA	NA	NA
WP_002212089.1\|3790873_3792085_+	maltose/maltodextrin ABC transporter substrate-binding protein MalE	NA	NA	NA	NA
WP_002212088.1\|3792271_3793849_+	maltose ABC transporter permease MalF	NA	NA	NA	NA
WP_002212087.1\|3793862_3794753_+	maltose ABC transporter permease MalG	NA	NA	NA	NA
WP_002212086.1\|3794895_3795303_-	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
WP_002212085.1\|3795437_3797084_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_002212084.1\|3797453_3798839_+	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_002228189.1\|3799406_3801092_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_002212081.1\|3801161_3806069_+	hemagglutinin repeat-containing protein	NA	NA	NA	NA
WP_002212080.1\|3806164_3809860_-	methionine synthase	A0A140XBC7	Dickeya_phage	4.6e-24	82.5
WP_002212079.1\|3811038_3812766_-	bifunctional isocitrate dehydrogenase kinase/phosphatase	NA	NA	NA	NA
WP_002212078.1\|3813021_3814329_-	isocitrate lyase	NA	NA	NA	NA
WP_002212077.1\|3814375_3815974_-	malate synthase A	NA	NA	NA	NA
WP_002212076.1\|3816394_3817324_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_002210692.1\|3824167_3825757_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.2e-68	49.4
WP_002210691.1\|3825816_3827103_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002355296.1\|3827250_3827904_-	DUF1481 domain-containing protein	NA	NA	NA	NA
WP_002210689.1\|3827953_3828229_-	DNA-binding protein HU-alpha	A7KV42	Bacillus_phage	3.6e-19	55.6
WP_002210688.1\|3828417_3829008_-	YjaG family protein	NA	NA	NA	NA
WP_002210687.1\|3829053_3829794_-	deoxyribonuclease V	NA	NA	NA	NA
WP_002210686.1\|3829823_3830891_-	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_002210685.1\|3831009_3831795_-	hypothetical protein	NA	NA	NA	NA
WP_002210684.1\|3831887_3832670_-	NAD(+) diphosphatase	NA	NA	NA	NA
WP_002210683.1\|3832766_3833276_+	sigma D regulator	NA	NA	NA	NA
WP_002210682.1\|3833651_3835697_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_002210681.1\|3835683_3836358_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_002210680.1\|3836347_3837145_+	HesA/MoeB/ThiF family protein	A0A1V0SAV8	Catovirus	1.6e-11	27.8
WP_002217275.1\|3837141_3837357_+	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_002217273.1\|3837358_3838174_+	thiazole synthase	NA	NA	NA	NA
WP_002210678.1\|3838166_3839297_+	2-iminoacetate synthase ThiH	NA	NA	NA	NA
WP_002213775.1\|3839728_3840187_+\|transposase	IS200/IS605-like element IS1541B family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-12	34.1
WP_002210677.1\|3840313_3844534_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	8.5e-67	27.0
WP_002210676.1\|3844662_3848691_-	DNA-directed RNA polymerase subunit beta	A0A0N9R0J7	Chrysochromulina_ericina_virus	1.2e-22	29.0
WP_002230058.1\|3849033_3849426_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_002210674.1\|3849492_3849990_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_002210673.1\|3850354_3851059_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002210672.1\|3851062_3851491_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_002210671.1\|3851681_3852227_-	transcription termination/antitermination protein NusG	A0A291AUS6	Sinorhizobium_phage	5.9e-13	28.3
WP_002210670.1\|3852228_3852612_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002210669.1\|3852862_3854047_-	elongation factor Tu	A0A2K9L516	Tupanvirus	2.0e-13	26.9
WP_001297096.1\|3855103_3855883_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|3855882_3856905_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_17

3967109 : 4006836

Escherichia_phage(25.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213759.1\|3967109_3967568_-\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_000255944.1\|3970335_3971358_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3971357_3972137_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210461.1\|3973800_3975462_+	HTH-type transcriptional regulator SgrR	NA	NA	NA	NA
WP_002214274.1\|3976401_3977394_+	thiamine ABC transporter substrate binding subunit	NA	NA	NA	NA
WP_002214276.1\|3977369_3978977_+	thiamine/thiamine pyrophosphate ABC transporter permease ThiP	NA	NA	NA	NA
WP_002210464.1\|3978963_3979674_+	thiamine ABC transporter ATP-binding protein ThiQ	G3M9Y6	Bacillus_virus	1.0e-20	34.1
WP_002210465.1\|3979742_3980510_-	DedA family protein	NA	NA	NA	NA
WP_002210466.1\|3980705_3983075_+	DNA polymerase II	A0A0P0YM26	Yellowstone_lake_phycodnavirus	1.5e-31	25.5
WP_002220588.1\|3983535_3986442_+	RNA polymerase-associated protein RapA	A0A1B1IUI1	uncultured_Mediterranean_phage	3.0e-23	37.6
WP_002210468.1\|3986697_3987051_-	hypothetical protein	NA	NA	NA	NA
WP_099156322.1\|3987072_3990486_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_002210469.1\|3990573_3992184_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002210470.1\|3992180_3993536_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002210471.1\|3993655_3994147_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002214737.1\|3994139_3994505_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_002210473.1\|3994510_3995128_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_002214739.1\|3995120_3996224_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002210474.1\|3998481_4000830_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.1e-14	32.9
WP_002210475.1\|4000933_4003522_-	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	1.9e-77	28.7
WP_002210476.1\|4003539_4004523_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002210477.1\|4004515_4006360_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002210478.1\|4006392_4006836_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_18

4413069 : 4457678

Escherichia_phage(28.57%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002216348.1\|4413069_4413906_+\|protease	rhomboid family intramembrane serine protease GlpG	NA	NA	NA	NA
WP_002208930.1\|4413940_4414699_+	DeoR/GlpR family transcriptional regulator	NA	NA	NA	NA
WP_100067904.1\|4414891_4416245_+\|transposase	IS3-like element IS1661 family transposase	A0A1B1P773	Bacillus_phage	1.1e-55	44.7
WP_002208933.1\|4416423_4417308_-	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_002208934.1\|4417540_4419976_-	bifunctional aspartate kinase/homoserine dehydrogenase II	NA	NA	NA	NA
WP_002208935.1\|4421514_4421832_+	met regulon transcriptional regulator MetJ	NA	NA	NA	NA
WP_002208936.1\|4422180_4422636_+	hypothetical protein	NA	NA	NA	NA
WP_002216737.1\|4423178_4423394_-	50S ribosomal protein L31	NA	NA	NA	NA
WP_002208938.1\|4423636_4425835_+	primosomal protein N'	NA	NA	NA	NA
WP_002216730.1\|4426187_4427216_+	DNA-binding transcriptional regulator CytR	NA	NA	NA	NA
WP_002208941.1\|4427281_4428127_+	cell division protein FtsN	NA	NA	NA	NA
WP_002208942.1\|4428226_4428751_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_002208943.1\|4428821_4430153_+	HslU--HslV peptidase ATPase subunit	A0A191ZC11	Erwinia_phage	1.2e-43	29.8
WP_002208944.1\|4430388_4431306_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_002208945.1\|4431447_4431933_+	ribonuclease E activity regulator RraA	NA	NA	NA	NA
WP_002228141.1\|4432049_4432634_-	DUF4232 domain-containing protein	NA	NA	NA	NA
WP_002215873.1\|4433263_4433503_-	hypothetical protein	NA	NA	NA	NA
WP_002208949.1\|4433715_4435008_+	HlyD family secretion protein	NA	NA	NA	NA
WP_000255944.1\|4435919_4436942_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|4436941_4437721_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002213759.1\|4439452_4439911_+\|transposase	IS200/IS605-like element IS1541A family transposase	A0A0A8WIU6	Clostridium_phage	9.4e-12	34.1
WP_002208953.1\|4440118_4440358_-	septal ring assembly protein ZapB	NA	NA	NA	NA
WP_002208954.1\|4440985_4441834_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.2e-13	27.5
WP_002208957.1\|4445081_4445516_-	DUF805 domain-containing protein	NA	NA	NA	NA
WP_002208958.1\|4445684_4446299_+	DUF1454 family protein	NA	NA	NA	NA
WP_002208959.1\|4446427_4447195_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_002208960.1\|4447426_4448662_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002208961.1\|4448798_4449536_+	PIG-L family deacetylase	NA	NA	NA	NA
WP_002208962.1\|4449532_4450246_+	4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase	NA	NA	NA	NA
WP_002208963.1\|4450311_4451739_+	anion permease	NA	NA	NA	NA
WP_002218867.1\|4451856_4452633_+	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002208965.1\|4452882_4453872_-	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002208966.1\|4454092_4455076_-	6-phosphofructokinase	NA	NA	NA	NA
WP_002208967.1\|4455293_4456196_-	CDF family cation-efflux transporter FieF	NA	NA	NA	NA
WP_002353252.1\|4456757_4457678_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	8.6e-73	54.3

Anti-CRISPR protein detection

Acr_ID: NZ_CP016273.1|WP_002214494.1|2040668_2041025_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP016273.1|WP_002214494.1|2040668_2041025_+|hypothetical-protein

2040668_2041025_+

118 aa aa

1984055-2083712

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location
NZ_CP016273_3	TypeI-F	3.7\|2412024\|32\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2412024-2412055	32	2006378-2006409
NZ_CP016273_3	TypeI-F	3.8\|2412084\|33\|NZ_CP016273\|CRISPRCasFinder,CRT,PILER-CR	2412084-2412116	33	2012290-2012258
NZ_CP016273_4	Orphan	4.1\|2537649\|33\|NZ_CP016273\|PILER-CR,CRISPRCasFinder,CRT	2537649-2537681	33	2014630-2014662
NZ_CP016273_4	Orphan	4.5\|2537892\|32\|NZ_CP016273\|CRISPRCasFinder,CRT	2537892-2537923	32	2011944-2011975

1. spacer 3.7|2412024|32|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016273 position: 2006378-2006409, mismatch: 0

aaaaagaatttgggattaaagttacccatcag	CRISPR spacer
aaaaagaatttgggattaaagttacccatcag	Protospacer
********************************

2. spacer 3.8|2412084|33|NZ_CP016273|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016273 position: 2012290-2012258, mismatch: 0

tcaatgcctgaatctctggcgtgatagctgcgg	CRISPR spacer
tcaatgcctgaatctctggcgtgatagctgcgg	Protospacer
*********************************

3. spacer 4.1|2537649|33|NZ_CP016273|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016273 position: 2014630-2014662, mismatch: 0

ccggcggtgatggcaattctacgtgggttcgtt	CRISPR spacer
ccggcggtgatggcaattctacgtgggttcgtt	Protospacer
*********************************

4. spacer 4.5|2537892|32|NZ_CP016273|CRISPRCasFinder,CRT matches to NZ_CP016273 position: 2011944-2011975, mismatch: 0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

3. NZ_CP016274

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30336 : 58213

Enterobacteria_phage(25.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213294.1\|30336_30744_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.7e-07	29.2
WP_002213244.1\|30767_31085_-\|transposase	transposase	NA	NA	NA	NA
WP_002213246.1\|31256_31715_-	hypothetical protein	NA	NA	NA	NA
WP_042469136.1\|31783_32053_+\|transposase	transposase	NA	NA	NA	NA
WP_002213256.1\|34664_36980_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	1.0e-279	51.6
WP_002213258.1\|37143_37695_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	5.9e-77	80.3
WP_002224338.1\|37713_38178_+	hypothetical protein	NA	NA	NA	NA
WP_002229829.1\|38316_38646_+	hypothetical protein	NA	NA	NA	NA
WP_086016640.1\|38745_39844_+\|transposase	IS3-like element ISYpe1 family transposase	S5WIU1	Leptospira_phage	1.4e-45	38.5
WP_002213267.1\|39992_40418_-	type III secretion system chaperone SycH	NA	NA	NA	NA
WP_000255944.1\|42206_43229_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|43228_44008_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002213403.1\|45132_45525_-	type III secretion system chaperone SycE/YerA	NA	NA	NA	NA
WP_002229754.1\|45718_46378_+	type III secretion system effector GTPase activator YopE	NA	NA	NA	NA
WP_002213360.1\|46517_46817_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002224342.1\|46809_47052_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_002213357.1\|47595_47769_+	hypothetical protein	NA	NA	NA	NA
WP_154020274.1\|47917_48154_-	hypothetical protein	NA	NA	NA	NA
WP_002213354.1\|48313_49279_-	ParB/RepB/Spo0J family plasmid partition protein	Q7Y3Y7	Yersinia_phage	3.1e-89	56.6
WP_002220902.1\|49275_50442_-	plasmid-partitioning protein SopA	Q7Y3Y6	Yersinia_phage	3.5e-196	85.3
WP_002229770.1\|52453_53083_-	hypothetical protein	NA	NA	NA	NA
WP_002213007.1\|53680_54229_-	type III secretion system effector YopK	NA	NA	NA	NA
WP_002213006.1\|54728_55697_+\|protease	T3SS effector cysteine protease YopT	NA	NA	NA	NA
WP_002213004.1\|55696_56095_+	type III secretion system chaperone SycT	NA	NA	NA	NA
WP_002222515.1\|56799_57219_+	hypothetical protein	NA	NA	NA	NA
WP_116442925.1\|57967_58213_+\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP016275

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP016273

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

3. NZ_CP016274

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection