CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP016592	Ketogulonicigenium vulgare strain SKV chromosome, complete genome	2 crisprs	csa3,WYL,DEDDh,cas5,cas8c,cas7,cas4,cas1,cas2	0	5	5	0
NZ_CP016593	Ketogulonicigenium vulgare strain SKV plasmid pKvSKV1, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016592_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016592_1

1851317-1852010

TypeI

I-C

Consensus_repeat	Method
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	PILER-CR
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	CRISPRCasFinder
GTCGCTCCCCCCACGGGAGCGTGGATAGAAACN	CRT

10 spacers

cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of NZ_CP016592_1

>merge|NZ_CP016592|1|1851317-1852010|PILER-CR,CRISPRCasFinder,CRT
GTCGCTCCCCCCACGGGAGCGTGGATAGAAACCCCGATCCAACCGCGAAGTGGGCCAGCCGCGATGGTCGCTCCCCCCACGGGAGCGTGGATAGAAACACTGTCACTCCGACTTGGAGAGCATCTACAATGACGTCGCTCCCCCCACGGGAGCGTGGATAGAACCAGTTGGCGTGCGGGCGTCCACATCTGAATGATGGTCGCTCCCCCCACGGGAGCGTGGATAGAAACTCATTGTAGATGGTGGTATCGAAACGCGACACCTGTCGCTCCCCCCACGGGAGCGTGGATAGAAACTCCCATAAAAAAACCCGCCTCTAAGGGCGGGCTGGTCGCTCCCCCCACGGGAGCGTGGATAGAAACTGCTTCCGGTAAAACTCCACCGCAGCGTGGAACGTCGCTCCCCCCACGGGAGCGTGGATAGAAACGATGCCGTCCTCGCGTCCCTCCAATCCAGCGCGCGGTCGCTCCCCCACGGGAGCGTGGATAGAAACAGCGACCAATGGCGCGTAGCGACACCCTATCAGGACGTCGCTCCCCCCACGGGAGCGTGGATAGAAACTACGCTATGACCCAGATCCTCCGGGGGCGCGCAACGTCGCTCCCCCCACGGGAGCGTGGATAGAAACCCCAGCAGGCGCGGCGCAGACGACAGGCGGGACGGTCGCTCCCCCCACGGGAGCGGGGATAGAAAG

>NZ_CP016592|1|1|1851317-1852010|PILER-CR
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	CCCGATCCAACCGCGAAGTGGGCCAGCCGCGATG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	ACTGTCACTCCGACTTGGAGAGCATCTACAATGAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAACC	AGTTGGCGTGCGGGCGTCCACATCTGAATGATG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TCATTGTAGATGGTGGTATCGAAACGCGACACCT
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TCCCATAAAAAAACCCGCCTCTAAGGGCGGGCTG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TGCTTCCGGTAAAACTCCACCGCAGCGTGGAAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	GATGCCGTCCTCGCGTCCCTCCAATCCAGCGCGCGGTCGCT
CCCCCACGGGAGCGTGGATAGAAACAGCGACC	AATGGCGCGTAGCGACACCCTATCAGGACGTCGCTC
CCCCCACGGGAGCGTGGATAGAAACTACGCTA	TGACCCAGATCCTCCGGGGGCGCGCAACGTCGCTC
CCCCCACGGGAGCGTGGATAGAAACCCCAGCA	GGCGCGGCGCAGACGACAGGCGGGACGGTCGCTC
CCCCCACGGGAGCGGGGATAGAAAG

>NZ_CP016592|1|1|1851317-1852010|CRISPRCasFinder
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	CCCGATCCAACCGCGAAGTGGGCCAGCCGCGATG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	ACTGTCACTCCGACTTGGAGAGCATCTACAATGAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAACC	AGTTGGCGTGCGGGCGTCCACATCTGAATGATG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TCATTGTAGATGGTGGTATCGAAACGCGACACCT
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TCCCATAAAAAAACCCGCCTCTAAGGGCGGGCTG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TGCTTCCGGTAAAACTCCACCGCAGCGTGGAAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	GATGCCGTCCTCGCGTCCCTCCAATCCAGCGCGC
GGTCGCTCCCCCACGGGAGCGTGGATAGAAAC	AGCGACCAATGGCGCGTAGCGACACCCTATCAGGAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TACGCTATGACCCAGATCCTCCGGGGGCGCGCAAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	CCCAGCAGGCGCGGCGCAGACGACAGGCGGGACG
GTCGCTCCCCCCACGGGAGCGGGGATAGAAAG

>NZ_CP016592|1|1|1851317-1852010|CRT
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	CCCGATCCAACCGCGAAGTGGGCCAGCCGCGATG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	ACTGTCACTCCGACTTGGAGAGCATCTACAATGAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAACC	AGTTGGCGTGCGGGCGTCCACATCTGAATGATG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TCATTGTAGATGGTGGTATCGAAACGCGACACCT
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TCCCATAAAAAAACCCGCCTCTAAGGGCGGGCTG
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TGCTTCCGGTAAAACTCCACCGCAGCGTGGAAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	GATGCCGTCCTCGCGTCCCTCCAATCCAGCGCGCG
GTCGCTCCCCCACGGGAGCGTGGATAGAAACA	GCGACCAATGGCGCGTAGCGACACCCTATCAGGAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	TACGCTATGACCCAGATCCTCCGGGGGCGCGCAAC
GTCGCTCCCCCCACGGGAGCGTGGATAGAAAC	CCCAGCAGGCGCGGCGCAGACGACAGGCGGGACG
GTCGCTCCCCCCACGGGAGCGGGGATAGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016592.1\|WP_013384682.1\|1849810_1850845_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP016592.1\|WP_014537828.1\|1860387_1861350_-\|GlxA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NZ_CP016592.1\|WP_013384683.1\|1850849_1851140_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP016592.1\|WP_014537827.1\|1860226_1860412_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016592.1\|WP_014537825.1\|1853615_1854338_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223487
NZ_CP016592.1\|WP_013384689.1\|1856945_1858169_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380561
NZ_CP016592.1\|WP_014537829.1\|1861656_1862598_+\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|200601
NZ_CP016592.1\|WP_014537823.1\|1836407_1837547_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP016592.1\|WP_013384673.1\|1837543_1839217_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
NZ_CP016592.1\|WP_013384674.1\|1839237_1839906_+\|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	unknown	unknown	gnl\|CDD\|181735
NZ_CP016592.1\|WP_014537824.1\|1840031_1840883_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP016592.1\|WP_013384679.1\|1846450_1848220_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_CP016592.1\|WP_013384684.1\|1852136_1853588_-\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143423
NZ_CP016592.1\|WP_013384686.1\|1854324_1855053_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213186
NZ_CP016592.1\|WP_014537826.1\|1859371_1860166_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|225130
NZ_CP016592.1\|WP_013384681.1\|1849169_1849814_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NZ_CP016592.1\|WP_013384690.1\|1858335_1859214_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|131350
NZ_CP016592.1\|WP_013384687.1\|1855049_1855976_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119323
NZ_CP016592.1\|WP_013384678.1\|1845689_1846454_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NZ_CP016592.1\|WP_013384680.1\|1848216_1849167_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458

Protein	Function_ID	Function_description	E-value
NZ_CP016592.1\|WP_013384682.1\|1849810_1850845_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP016592.1\|WP_014537828.1\|1860387_1861350_-\|GlxA-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	2.28262e-90
NZ_CP016592.1\|WP_013384683.1\|1850849_1851140_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.2587e-33
NZ_CP016592.1\|WP_014537825.1\|1853615_1854338_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223487	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	1.73443e-106
NZ_CP016592.1\|WP_013384689.1\|1856945_1858169_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380561	cd06338, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.	2.78488e-101
NZ_CP016592.1\|WP_014537829.1\|1861656_1862598_+\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|200601	cd10979, CE4_PuuE_like, Putative catalytic domain of uncharacterized prokaryotic polysaccharide deacetylases similar to bacterial PuuE allantoinases. The family includes a group of uncharacterized prokaryotic polysaccharide deacetylases (DCAs) that show high sequence similarity to the catalytic domain of bacterial PuuE (purine utilization E) allantoinases. PuuE allantoinase specifically catalyzes the hydrolysis of (S)-allantoin into allantoic acid. It functions as a homotetramer. Its monomer is composed of a 7-stranded barrel with detectable sequence similarity to the 6-stranded barrel NodB homology domain of DCA-like proteins in the CE4 superfamily, which removes N-linked or O-linked acetyl groups from cell wall polysaccharides. PuuE allantoinase appears to be metal-independent and acts on a small substrate molecule, which is distinct from the common feature of DCAs which are normally metal ion dependent and recognize multimeric substrates.	2.57323e-120
NZ_CP016592.1\|WP_014537823.1\|1836407_1837547_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	2.1095e-120
NZ_CP016592.1\|WP_013384673.1\|1837543_1839217_+\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	9.82611e-72
NZ_CP016592.1\|WP_013384674.1\|1839237_1839906_+\|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	gnl\|CDD\|181735	PRK09262, PRK09262, hypothetical protein; Provisional.	3.94026e-69
NZ_CP016592.1\|WP_014537824.1\|1840031_1840883_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.67534e-30
NZ_CP016592.1\|WP_013384679.1\|1846450_1848220_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NZ_CP016592.1\|WP_013384684.1\|1852136_1853588_-\|aldehyde-dehydrogenase	gnl\|CDD\|143423	cd07105, ALDH_SaliADH, Salicylaldehyde dehydrogenase, DoxF-like. Salicylaldehyde dehydrogenase (DoxF, SaliADH, EC=1.2.1.65) involved in the upper naphthalene catabolic pathway of Pseudomonas strain C18 and other similar sequences are present in this CD.	0
NZ_CP016592.1\|WP_013384686.1\|1854324_1855053_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	2.65794e-100
NZ_CP016592.1\|WP_014537826.1\|1859371_1860166_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	3.16157e-14
NZ_CP016592.1\|WP_013384681.1\|1849169_1849814_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	2.6673e-40
NZ_CP016592.1\|WP_013384690.1\|1858335_1859214_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|131350	TIGR02297, AraC-type_DNA-binding_domain-containing_protein, 4-hydroxyphenylacetate catabolism regulatory protein HpaA. This putative transcriptional regulator, which contains both the substrate-binding, dimerization domain (pfam02311) and the helix-turn-helix DNA-binding domain (pfam00165) of the AraC famil, is located proximal to genes of the 4-hydroxyphenylacetate catabolism pathway.	2.13957e-28
NZ_CP016592.1\|WP_013384687.1\|1855049_1855976_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	1.9332e-49
NZ_CP016592.1\|WP_013384678.1\|1845689_1846454_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	6.53478e-97
NZ_CP016592.1\|WP_013384680.1\|1848216_1849167_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.38636e-150

>NZ_CP016592.1|WP_013384683.1|1850849_1851140_+|CRISPR-associated-endonuclease-Cas2
MLVLVTYDVNTLSDGGKKRLRQVARACEDWGQRVQFSVFEIELDPAQWTKLRARLESIIDAKTDSLRYYFLGTNWERRIEHVGAKPAKDLNGPLII
>NZ_CP016592.1|WP_013384682.1|1849810_1850845_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTVYVTTEGAALKKDGENLVAEIEGSEKARVPLHMVASVVTFGPIFVSPALIGTCAERGITIALMDRIGRFQARIEGPVSGNVLLRRAQYRTADDAVDVVRSIVLGKLANQRAVIRRGLRDYGDEMAAPVRDALERASDRIEMILRRVQVKDDSIDLLRGAEGEAATLYFGVFNHLIRSPDATLHWTGRSRRPPLDPMNALLSFLYTLLTHDCRSACEAVGLDPAVGFLHRDRPGRPSLALDLMEELRAPLADRLALSLVNRRQLRAGDFRQMDNGAVLLTDEARKTVLTAWQERKKEERLHPFLNEKAPFGLVPYLQAQMLARHLRGDIEAYPPWFWS
>NZ_CP016592.1|WP_013384681.1|1849169_1849814_+|CRISPR-associated-protein-Cas4
MGAEEDAIPLSALQHAVYCLRQAALIHLERLWVANRFTAEGDVLHAVADKGGARRARGVRRVMSLPLASARLNLIGTADLVEFIPGPAGEVAFPVEYKRGKPKLHRADEVQLCAQALCLEEMTGQPVPEGALFYAHTKRRVTVPFDTELRALTQNAAQSLADILASRITPAPTAHKSRCRACSLHEACRPETYARPVLAWRDQMLARSLKDISE
>NZ_CP016592.1|WP_013384680.1|1848216_1849167_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTTLSRRHDFVLIFDVTNGNPNGDPDAGNQPRLDPETGHGLVSDVSLKRKIRNYVELAHEGKDGHHIYVQEGAILNEKHRAAYIAKRPGDEKAKTDKKLNPKDDAEAKELRDWMCANFFDVRTFGAVMSTGINCGQVKGPVQMTFATSVERILPAEITITRMAATNEAEKKKAEEGSDGDQRTENRTMGRKHIVPYGLYVAHGFVSAKFAERTGFSEADLDLLLEALKNAFEHDRSAARGEMATRKLIVFKHENALGNAPAHELFDRVRIGRNLAGEFRPIGDSRLDNQPPARKFGDYLIEIDREALPAGVDIIEL
>NZ_CP016592.1|WP_013384679.1|1846450_1848220_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSVLSSLSRAYERLPDAPPYGFSSEKIGFCIVLNADGSVHDVIDKRQDDKKRSPAMLLVPQAVKRTAGIAPNFLWDKTAYVLGVTAGEGKRTADEHAKFREMHVQWLAGTQDEGLLALLRFLDAWTADRFTAPVWPEDMRDQNIVFALASEYRERYIHERSGAKEIWQRLGTEGASDPQICLVSGDPAPIARLHPSIKGVWGAQTAGASLVSFNLDAFTSYGHEQGDNAPVSEVATFQYTTALNRFLEKDSGHRLQIGDASTVFWADASGLISEMAESLFAGMFDTPEAAHDDDSIETKKIAAKLERIRRGERLDEVEPQLTQGVRFHVLSLAPNAARLSVRFYWENDFAQLTRNYQAYLEDTKIEPPPRDGWPPLWRYLVELAVLNKRENIPPNLAGEWTRAILTRTPYPMTLLATALMRIRSDGEVNALRAAVLKSVLVRNFNKEAPVALNPTFSDSKGYLLGRLFAAYEEVQREALGRNVNATIKDKFYGAASASPQKVFATLDSGAQNHFTKLRKINAGRAVNLDQLIMSIMDQMSPDKDPIPAFLNAPEQGLFGLGYYHQRSDFFRKRDTKTDSVTETQPETTA
>NZ_CP016592.1|WP_013384678.1|1845689_1846454_+|type-I-C-CRISPR-associated-protein-Cas5
MTYGIRLHIWGTHGLFTRPELKVERASYDVITPSAARGILEAIHWKPAIRWIVDRIHVLEPIRFQSIRRNEVGHKAPAGKIRAAMNRGDLADLQILVDQDRQQRASNVLVAPAYVIEAHFDLTAKAGPDDTVGKHLDIFNRRAAKGQCFNQPSLGTREFVAHFALVPPDAVIPSPDGHSWGAMLHAGQTNGAPRPSRAPEAETSDLGFGTPRDLGFMLWDIDHMAPGRPSMFFRATLRDGIVEIPAPGSPDIKR
>NZ_CP016592.1|WP_014537824.1|1840031_1840883_+|LysR-family-transcriptional-regulator
MAAAARQLNIAQPALSGHIAQIEEHYALQLFQRHARGVTLTPAGEALLRHARRILENLSEAEAELRHLSPVTTRAPVRLGLLPSWGASLAPAIIQATQLALPDIALRIVEMRHDESLDAIRQQNIDLAVVLEDTAPAQTQLLGSEALLYVSHVAVADRMSFRDVAALPLILPSAANLLRHQLDKAAKAAHVVLGPVMEIDGQDTIKSAVKAGVAGSIMSWNSIRNECLDHSLSACLIDDPEITRNVYLRRGEHVPANLAEAFFVVLRQVAEDNSYSRLRHART
>NZ_CP016592.1|WP_013384674.1|1839237_1839906_+|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase
MMAHVRRSFTRPSPEAIDAIRPYSPATVHEAQGKLGALDSRIKPLRHGWQICGSAITAQCHIGDNLMIFEAINLAKPGDVLVLSAGNNPEQGGFGDVLAAACRGKGIAGLIIDAGVRDGRGLRAGDFPVFSLGLCVKGTSKDTLGTVNMPVMVGNQLITPGDIIVADDDGVVVVRQEPFALAKACEAREASEAKLIEMHLSGRMEIEDRYDMMRAKGCVWED
>NZ_CP016592.1|WP_013384673.1|1837543_1839217_+|iron-ABC-transporter-permease
MNALQKPKISAYSVVAFFCAALVVVLIAYPLVRMLWNTVLGGNLQQGLSVVMQPWFGQVFLNTAIVVGISTAFAVAIGGSLAWINQRTDAGMGAVGGLMPIIPLLIPNVAMSIGWVFIAAPRVGFLNGWLATLPDWMSFQVNIYSWAGMIFIYTINGVPYVYLIAAAAFRNMDPALEEASRINGAGIWRTFWKVSLPSVKPALVSSALLLTITSIGIYSIPAVIGTTAKIDVLTTRIVYLLNREFPPRMPEAQMIGVIILILVGVLWWVQGRWAGKGQFATVGGRATGGGKLEMGRWKWPARTLTLIYLACTSILPLAALAVVALQPFWSPRINPAIFSLNNFNQALFVNGMAVSSIRNSLFYSSIGALIAMGIAVVIAIYTAERKNLFGKGLDTAIKSSAAIPNLILGVGFLIAFAGAPFYLSGTAMILILAFVVMYISPGSIAATSAITQIGRDLREAARINGASEGRMVRRVILPLAMPGFIGGWAIVFVHMMGDLSAAALLAGITNPVVGFAILSIWEAGTFGVLAAFSMMLCLINIFVIAAMFGLGRLIAKR
>NZ_CP016592.1|WP_014537823.1|1836407_1837547_+|ABC-transporter-ATP-binding-protein
MTSHCAPTPPRIEVVDLVKSYRRENGTVITPVDHIDLIVAQNELVVLLGPSGCGKTTLLRCVAGLERPDSGEIIVDGKVVFSSRKGIYEPPDRRALAMVFQSYALWPHMTVAQNVAFPLQSQKVATPEINERVSKALSMVGVGGLERQFPGRISGGQQQRVALARALVTNSSVVLFDEPLSNVDAQVRAQLRFELQSMQRRLQFSGLYVTHDQAEAMELGQRVAVLDNGKISAIGAPWDVYDRPTNEYVARFIGVANMWRGTVTCTGTDVCVETPLGPIRVHGGGASHAVGTALTVVARPEKLTLTAERPTGDTNAIPVMVEAVMFSGAHTEVVCRAGDGSAVTVWTGAHEATSQLARMGTAWLCALPADLRLVPTGAA
>NZ_CP016592.1|WP_013384684.1|1852136_1853588_-|aldehyde-dehydrogenase
MDLLGLLINNETLPASGGKTFTRKNPISGEVATEAAAATTDDAQRAADAAAAAFPEWSRSSPKTRRTVLLKAADMLEANGPQFVAAMGAEIGATAGWAMFNVTLAADMLREAASLVTQIKGEIIPSNRPGSTAMAVRQPAGVVLAMAPWNAPVILGVRALATPLACGNTVVMKTSELCPRTHHLIVSSLLQAGLPAGVLNAVSNAPEDAAEIVEALIAHPAVRRVNFTGSTRVGRIIAEKAGRYLKPALLELGGKAPFVVLDDADLDEAVAAAAFGAYMNQGQICMSTERIVVMESVADAFVEKLAVKARTLIAGDPREGKTPLGSVVDVSAAQRIEQLIKDATSKGAVLAAGGRIDGTLMDAALLDHVSPAMRIYGEESFGPVVTVVRVGSIDEAVRVANDTEYGLSSAVFGGDVNRALAVARRIESGICHVNGPTVHDEAQMPFGGTKASGYGRFGGNWGIHEFTELRWITVQDGHIHYPI
>NZ_CP016592.1|WP_014537825.1|1853615_1854338_-|ABC-transporter-ATP-binding-protein
MLMLKIANLSLRYGRHLALQCVNVAVARGETVVILGANGAGKSSALKAVGGIVRPDAGSVVTLDDVPLLGAPAHQIVDRGLALVPEGRGVFADLTVAENLLLGANPKRARAGEGARRDFVYTLFPRLAERRRQTVRTMSGGEQQMVAIGRALMSNPDYLLLDEPSLGLAPIVVAELFAALRRVKETGVAILLVEQNVALSLSLADRGYLMEAGRIVGEGTADTLRNDPAVQNAFLGGSAA
>NZ_CP016592.1|WP_013384686.1|1854324_1855053_-|ABC-transporter-ATP-binding-protein
MTVLLQVDGLKKQFGGLMAVNDLSFTVAEGEILALLGPNGSGKTTVMNLISGALPATAGRIQLDGVQISGLPAHRIARLGVARTFQLVRILPSLTVAENVIAALAFRAQPLWGDDAARAAEALLAEVGLAGRGGEYAADLTYIDQKRMELARALGAAPKLLLLDEWLSGLNPTELRVGIALILSLKARGMTIMLVEHIMEAVRALCPRTVVMNAGRKIADGPTNDVLADPAVVAAYLGGVDA
>NZ_CP016592.1|WP_013384687.1|1855049_1855976_-|branched-chain-amino-acid-ABC-transporter-permease
MSARTLTGLGLAALALVMLAWLPSQLDAYGVGLLLGMTGYVTLATAWALFSGPTRYISLATVAFFGIGAYTVAVLSEAMPYPMVLITAALVGGAVALVVGLATLRLAGVYFVIFSFGLAELVRQLVTWYEVNVTGTLGRYIFLPITAQQIYWQLLALCALTFLIGWLIARSRLGLALRVIGDDEAVAAHTGINIAGAKLALFVISATLITLVGAIQAPRWTYVEPAMVFNPTTSFLTVIMALLGGAHRLWGPILGAIPLFLLFEWLSANFPNHYAIILGLLFITIVFLVPKGVLALVESAFARRRRLQ
>NZ_CP016592.1|WP_013384689.1|1856945_1858169_-|ABC-transporter-substrate-binding-protein
MIMFSRRLALRSFGATIAVAAAMTGFSASAQQTSIKIGYAVSLTGGNAGGAGITTLPNYRLWVSEVNAAGGLELPDGTRLPIEVVEYDDRSSTEEVVRAIERLATQDQVDFILSPWGTGFNLAVAPLLDRFGYPQLASASVTDRADEFAQRWPRSFWLLGGGADYAGGLADVLATATASGVMNGDVAIISVADGFGIDLINAARPAFAAAGLNIVMDRTYPPGTTDFSPMLNEAKSSSATAFVAFSYPPDTFALTQQAQVADYNPAVFYLGVGAPFPTYLGANGANAEGVMSLGGIDTSNAAMMDYRARHEAFAGQPPDSWASMITYAGLEILQEAIKRAGLDRDAVSAEIASGSFTTILGETQLQNNQLRDLWLTGQWQDGTFVAIEPTDRPGASAAIVPKQPWAN
>NZ_CP016592.1|WP_013384690.1|1858335_1859214_+|helix-turn-helix-domain-containing-protein
MTLRPTHSHLDMLQEVAAQVIATTLDTAAWRMLGRRNRIFVLSAGTGSITYKGESHLLAAPGLVWVPAGAPAQLSLDAGSKGAWLAISDRAILQVDLAGNIAEDMRRFAQRPQFGRKISREMAARLIGLMALMAEELQRSEAGMQEMIRHHLSILAILLWRGSDLRPIAARPAPRVIFSEFLRLVDQHMRAHWRVSDYARYLGVSIDRLTSTVQRDTGQPPLAIIHTRLHAEACQMLETSAMQIAEISASLGFPDPAYFSRFFKRISGYSPRDYRNGLYREVTSGQAWAAWP
>NZ_CP016592.1|WP_014537826.1|1859371_1860166_-|MBL-fold-metallo-hydrolase
MANTTMTKKPVQITQVRNATLVVEYANTKFLIDPLFAAQGAFPGFAGSASSQLANPLVPLPIAQEQLIAVDAVIVTHLHEDHWDAAASAALPKDMPLFAQNEEDADKIRNEGFTDVRVLTQQSQFNGIGLCKTGGQHGTDATLDVIPLGEVCGVVFSHPQYATLYIAGDTIWNDHVQTAIDSHQPDAIVLNIGNAVFMGYDPIIMGLEDAVAVHRAAPNAILIASHMEAINHCILSRQTLYDYAKANGFDTRLLIPADGETVSV
>NZ_CP016592.1|WP_014537827.1|1860226_1860412_+|hypothetical-protein
MSSRQSGGFVTIHVGHNLFAASLFEARHDLIDKNRRGRWRNRQTTGRSRHNGDHHVRKRLR
>NZ_CP016592.1|WP_014537828.1|1860387_1861350_-|GlxA-family-transcriptional-regulator
MSQNEVLEVGLLIYPGVQMASVLGMTDLFEMANHVNGKDAAKTIRISHWKTTEDDGAPARVFDSFPLAESEPAVLVVPPAFGVPITPEVAQVYAPWLRQRHGGGTALGSVCTGSFLLAETGLLDGRRITTHWTVDAYLRARFPKVALDADQVIVEDGDIMTGGGAMSWIDLGLRIVDRLLGPAIMAETARSLLVDPPHREQRYSSTFAPRLNHGDAAILKVQHWLQATSAKEGDVERLANVAGLEGRTFLRRFKKATGLTTTEYFQRIRVGRAQELLQAGSQSIDQIAWDVGYSDPGAFRKVFTRIIGLSPGDYRKRLRT
>NZ_CP016592.1|WP_014537829.1|1861656_1862598_+|polysaccharide-deacetylase-family-protein
MPQSTNTSSPMRSDTGQYRFAPMRGRPRLHWPGNARMAFWVAPNIEHYELDPPVNPNRSPYARVQPDVLNYGWRDYGNRVGFERMARVMADRGIRGSVSLSVAVIEHFPDIIAQCNDLGWEMFSHGVYNTRYFYGMTEDQQRQVIRDSRESLARVGQTLDGWLTPAITPSLATQDLLAEEGVRYTLDYFHDDQPMPVKVRNGRLISVPYSIEMNDVPMVNWQNASPTAMLDSLKAQFDRLYAEGAGNPNVMCFATHPFLLGQPHRISVLTEFLDYVKSHDQVWYPTAREIADYYYTHHYDRVNTWLASLEESA

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Crispr_ID: NZ_CP016592_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016592_2

2138731-2138830

Orphan

Consensus_repeat	Method
GGACGAGGGCAAAGCCGCCTTCCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP016592_2

>merge|NZ_CP016592|2|2138731-2138830|CRISPRCasFinder
GGACGAGGGCAAAGCCGCCTTCCGTTGGTATACGGAACTGAACACCGCGCAGCATGTGGGCGCGCCCGGCTTTATGGACGAGGGCCAAGCCGCCTTCCGT

>NZ_CP016592|2|2|2138731-2138830|CRISPRCasFinder
GGACGAGGGCAAAGCCGCCTTCCGT	TGGTATACGGAACTGAACACCGCGCAGCATGTGGGCGCGCCCGGCTTTAT
GGACGAGGGCCAAGCCGCCTTCCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016592.1\|WP_013384825.1\|2129090_2130236_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016592.1\|WP_013384833.1\|2134222_2136577_-\|PIG-L-family-deacetylase	unknown	unknown	gnl\|CDD\|376836
NZ_CP016592.1\|WP_014537901.1\|2128174_2129035_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223673
NZ_CP016592.1\|WP_013384843.1\|2146720_2147068_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016592.1\|WP_013384840.1\|2143678_2144584_+\|ribokinase	unknown	unknown	gnl\|CDD\|238571
NZ_CP016592.1\|WP_013384834.1\|2136595_2137804_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_CP016592.1\|WP_013384837.1\|2140251_2141100_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP016592.1\|WP_013384844.1\|2147692_2147845_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016592.1\|WP_013384842.1\|2145943_2146606_-\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP016592.1\|WP_013384832.1\|2133334_2134222_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP016592.1\|WP_014537900.1\|2127464_2128169_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_CP016592.1\|WP_013384836.1\|2139319_2140255_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP016592.1\|WP_014537902.1\|2132713_2133328_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NZ_CP016592.1\|WP_083205735.1\|2131081_2131873_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|131484
NZ_CP016592.1\|WP_013384839.1\|2142620_2143682_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NZ_CP016592.1\|WP_013384845.1\|2148319_2148526_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016592.1\|WP_013384829.1\|2131869_2132709_+\|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl\|CDD\|223268
NZ_CP016592.1\|WP_013384841.1\|2144596_2145940_-\|Ktr-system-potassium-transporter-B	unknown	unknown	gnl\|CDD\|273349
NZ_CP016592.1\|WP_044008068.1\|2130237_2131095_+\|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	unknown	unknown	gnl\|CDD\|223268
NZ_CP016592.1\|WP_013384838.1\|2141103_2142621_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|176463

Protein	Function_ID	Function_description	E-value
NZ_CP016592.1\|WP_013384837.1\|2140251_2141100_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	7.79151e-84
NZ_CP016592.1\|WP_013384833.1\|2134222_2136577_-\|PIG-L-family-deacetylase	gnl\|CDD\|376836	pfam02585, PIG-L, GlcNAc-PI de-N-acetylase. Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.	6.03897e-16
NZ_CP016592.1\|WP_014537900.1\|2127464_2128169_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	5.64911e-106
NZ_CP016592.1\|WP_013384840.1\|2143678_2144584_+\|ribokinase	gnl\|CDD\|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	1.42854e-44
NZ_CP016592.1\|WP_013384834.1\|2136595_2137804_-\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	3.23373e-43
NZ_CP016592.1\|WP_013384842.1\|2145943_2146606_-\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	1.46251e-42
NZ_CP016592.1\|WP_013384832.1\|2133334_2134222_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	1.02628e-13
NZ_CP016592.1\|WP_014537901.1\|2128174_2129035_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.08621e-38
NZ_CP016592.1\|WP_013384836.1\|2139319_2140255_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.50085e-74
NZ_CP016592.1\|WP_014537902.1\|2132713_2133328_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.43447e-05
NZ_CP016592.1\|WP_083205735.1\|2131081_2131873_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|131484	TIGR02431, p-hydroxybenzoate_hydroxylase_transcriptional, beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family. Member of this family are IclR-type transcriptional regulators with similar DNA binding sites, able to bind at least three different metabolites related to protocatechuate metabolism. Beta-ketoadipate is the inducer for PcaR, p-hydroxybenzoate for PobR, and protocatechuate for PcaU. [Regulatory functions, DNA interactions].	3.08101e-57
NZ_CP016592.1\|WP_013384839.1\|2142620_2143682_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	4.86062e-177
NZ_CP016592.1\|WP_013384829.1\|2131869_2132709_+\|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase	gnl\|CDD\|223268	COG0190, FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism].	2.41878e-53
NZ_CP016592.1\|WP_013384841.1\|2144596_2145940_-\|Ktr-system-potassium-transporter-B	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	1.82325e-86
NZ_CP016592.1\|WP_044008068.1\|2130237_2131095_+\|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	gnl\|CDD\|223268	COG0190, FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism].	2.47905e-108
NZ_CP016592.1\|WP_013384838.1\|2141103_2142621_+\|argininosuccinate-lyase	gnl\|CDD\|176463	cd01359, Argininosuccinate_lyase, Argininosuccinate lyase (argininosuccinase, ASAL). This group contains ASAL and related proteins. It is a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASAL is a cytosolic enzyme which catalyzes the reversible breakdown of argininosuccinate to arginine and fumarate during arginine biosynthesis. In ureotelic species ASAL also catalyzes a reaction involved in the production of urea. Included in this group are the major soluble avian eye lens proteins from duck, delta 1 and delta 2 crystallin. Of these two isoforms only delta 2 has retained ASAL activity. These crystallins may have evolved by, gene recruitment of ASAL followed by gene duplication. In humans, mutations in ASAL result in the autosomal recessive disorder argininosuccinic aciduria.	2.28477e-155

>NZ_CP016592.1|WP_013384834.1|2136595_2137804_-|ROK-family-protein
MVSAMTTAEGATEKRKRAIGANPERNRAHNRSLVLNLLREHGQIGRAAMARHTRLTQQAVGNIIDELLLEGMVIETGRLRVGRGQPARQFALNPCGPVSLGVEIAAGHLAIVFQALTGAIRARSIVPLADTAPAPVIAALVAQIEKLKSEAGAPEIIGMGVVMPGPFEIEGISAVGPATLKGWAGLDPAALIADATGIGTVVYENDATAAAVFESLHGVGRGLRDFCHVYFGVGLGLGLIHDGRPLRGAFGNAGEIGQIAVPPRGGGAAAALEDRASVFALRDFLRETRGAPDDLDLLASLDPAEDPALQDWIARAADQLSPVLAILENIFDPETITLGGLMPRPIIEAMIDCLQPLPVTVSSRSARGLPRLMLAQTGPYTAALGAAAMPFMDQNTTATLRQ
>NZ_CP016592.1|WP_013384833.1|2134222_2136577_-|PIG-L-family-deacetylase
MLTDRNRLFRRIADPRMVRLARALGRLGSTVTMMNTGAHPDDEQTELLAWFSFGRNMRVVIACSTRGEGGQNALGPERGAALGLVRSRELEESARVIDADIAWLGHGPVDPVHDFGFSKDGKDTLERWGRARVIDRLVRAYREYRPDIVLPTFLDVPGQHGHHRAMTEAAEAALALAADPTYEVDGLAPWRVAKYYLPAWSGGGSTYDDELPPPPATVDVRVEGFDPVSGMRYDQIGEASRGYHASQGMGTWRATPRRHWALHGTAPEGDILDGLPATLGALADVAGAPAELALAASEIAKARAAFPDDQAMITALVAAHKAFSAPMGADFDALHGHRIRQKIAEVEAALALAAGVDVAAWLQDPLVPGRSATLAVWVNAGHATLRGIAAAASDGIAQKGGSEERDGLHLLTLAVPADLSPASRYLPGWARLGGNGILAASVTVEVGGITFALPVDLEEEPLLQPAASVTPSADAVLVNLNDPQPVHFAMTGTASAASLGLGSIDGLTVENADGHVTLTASGLAPGKTRLPISVAGAAGWQAKPINYGHIGRLAQVVPAGVDILALDLKIPDGRVGYIGGGADRVGLWLERMGVDVVDLDAEAFDAARANGFAGFDTLVVGIFTFGLRPDLAAATADLRAWVHAGGNLVTLYHRPWDNWKPDETTPAHMVVGSPSLRWRVTRPGAPVTILEPDHDLLAGPNTITHADFDGWDKERGLYFLSSWDQVYQPLLAMSDPDEQPLLGSLVTGRIGKGRHTHTALVLHHQMDRLVPGAFRLMANLIQPA
>NZ_CP016592.1|WP_013384832.1|2133334_2134222_-|DMT-family-transporter
MKPATALDDQTSAAEMRQGMTWVLLDMALVSAMTVMVKKGGVDFPAVQMVFFRSLVGLVAVLPLVLRHWRVIRQTRNVKRNVFRVTCNAVALSCNWGALTILPLATANAIGFLRPLIVMVMAIFLLSERVTGWRWAGAALGLMGVGVMLLPSLTGMGEAQDHLLGYAFAGGAILFGAMATIQTRALKGENTTVMMVFYTVGLTLFTAIPAFFVWQPVALHHLPHLLGIGIIAQVAQYCYLRGYQLAPASKLAPLGYLSLIFATVMGYVFFDEVPTVYTAGGAIVIIIGLIVARRA
>NZ_CP016592.1|WP_014537902.1|2132713_2133328_+|nuclear-transport-factor-2-family-protein
MKKLIASFAIAASIAAPVFADTEVRPGVFFAGTVETAGSDRAVMQDLIFDLATAWAVCDRDAMANAITDDVSFSYPTSAVNGREAIMADLEAFCGAATDTSLYFPADAFYIDVDTGRIAAEVQFRTFQRGNRQVVNDVWIATVTDGKVSVIKEYLDGRVKDLQAQGVLQLEESPDFLTPWPPRTEAWASCFPIVRAAPTNDCVQ
>NZ_CP016592.1|WP_013384829.1|2131869_2132709_+|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase
MTTIFTGFDLAADILQGVRADIATLGRAPVCVTLFDDSSAPARAYLNRQITLARGAGIDLRPMGYADAQLAQLAADARVDAIATLYPLPSGLTPMGAAQAIGGGKDIDGQHPNHAGPLLLGDGTLRPAATAQASLICARAILGDLAGAEIVLIGASRLIGRPLAMLLLDAGATVTTCHIQTRDLARHTRAADLVISAAGVPALLTADNIAKGGRILDLAIIPKDGSLVGDADLPSLMGHAALVSAVPDGVGPVTTACLFANIAAAAKSRAMNLPLLQQD
>NZ_CP016592.1|WP_083205735.1|2131081_2131873_+|helix-turn-helix-domain-containing-protein
MPATDENRALFEDDKEISLTLARGLDLIEAFAGDERRLSIPELAARTGMNRTVVRRLVRTLEKKGYASADRGQYELTPHILRLIRGFIEGRSLPQIVHPLLRAAAEDIGESVSFAMLDDTEAVYVAHAFLPARFTLNMVTVGSRAPLLPTAVGRVIVAFLPDIERSAILSRLSPQAHTPQTETDAARLDAIFADCRRLGYCMADGEYVEGVASLAVPVFDGMRRVTGALSIIFPTHGHDATEIAEKLAPRMQATASALGSALQ
>NZ_CP016592.1|WP_044008068.1|2130237_2131095_+|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase
MMALLLDGDALAAKLRQQMTERVAASGIRPVMATVLVGDNPASESYVARKHKDCREIGIEALRIRLPAGASPEQVLAEVARLNDDPSVDGFFVQFPLPEGHDEQAIAAAIRPDKDIDGLHPENLGRLITGKGGIPPCTPMAVLSLLRGYNVPLAGKHVVIIGRGLLVGRPLAMVLSAPGVDASVTLLHSQTPDIAAFTRNADVVIAAAGHPELIRADMIRAGATVVGVGITYGDDGAMVSDIAADVSAIAGAVTPAHGSVGSLTRAMLLQNLINLALEKHSHARN
>NZ_CP016592.1|WP_013384825.1|2129090_2130236_+|hypothetical-protein
MNRILTALTASVAAFAGTTASAGEFATAHYTTPLADVCPSPFYIQKDWLAQAEHGGLYQMIGAGGTMESGAYRGPLGATGIELAILEGGGGIGLGDGETAYSALFNGNSKAGVIPHLGFQELDNAYIFSNLFPVVGVFVPLDIAPSGLIWDTGTYPDGFHSVDDLKAFGESGAGMIYVSTITRTFGLWLVEQGVSRDAFVEGYRGDLENFVANNGTWLNQGFVTTEVFNLSNGMNWAKPVDAVTVNELGYPTITGMVSVAQPRLEELAPCLELLVPIMQQAAVDYINDPAEVNQLIADFTAGGFSASWWRATPELNAYSAAAQRDRGIVGNGNNATIGDFDLDRAAAMLELVKPMLDDRANPDVTVDDVVTNRFINPEIGL
>NZ_CP016592.1|WP_014537901.1|2128174_2129035_+|ABC-transporter-permease-subunit
MTEIAPKIRTEAYAPTPVAPPRTPAQKFAATFLPPLIMGVLVVLLYWVVRESLPAHRQFLMPSASGMWDKALSQPAVWAELGSRSLTTLTIALTGLAFSIPIGMALGIIMFRFFVMERAVYPFLVALQSIPIMAIIPLIQSALGFGFMPKVLIVILFTFFAIPTTLLLGLKSLDQGVLNLFRLQGASWWTMLRKAGLPSSAPALFAGFRISTSMAVIAAVTSELFFMAGRGGLGQMLVNAKTDFKYEQMYAALIASATLSISIFVVFTLVGNRIFASWYETAERKS
>NZ_CP016592.1|WP_014537900.1|2127464_2128169_+|ABC-transporter-ATP-binding-protein
MQYPDGTIALEGIDLTIRKGEFVSVVGPSGCGKSTLLKLASGLEAHTGGQIRVDRSNLGYTFQDATLLPWRTVLPNVELLMELRGIPPEERRRVALEQIELVGLKGFENHYPKRLSGGMRMRASLARSLALNPAVFMFDEPFGALDEITRERLNDELIALYLRNGFTGMFITHSIPEAVYMSSRVIVMSRRPGRIIADFPIPFAYPRQPELRYDPEFSRIAGEVSVALRHAIEE
>NZ_CP016592.1|WP_013384836.1|2139319_2140255_+|sugar-ABC-transporter-permease
MSVTDPNGAAEGRPGLWNRLGIRTKHVLWAWAFLAIPVLFYVVIRFYPTFDAFWLSLTDGNIRRGPSFIGLENYARMYADPVFWKVFGNTFLYLLIGTPVSLVISFTIAYYLDRVRFMHGLIRALYFLPYLTTAAAMGWVWRFLYQPVPIGMINSFLTSIGLEQQPFLRSTDQALMAATIPAIWAGLGFQIIIFMAGLRAIPSSFYEAARIDGLGEWAILRKITLPLLKPTTIFLVVLSSIGFLRIFDQVQSLTANDPGGPLNATKPLVMLIYQTAFSSFRMGYASAQTVILFLVLLLISLLQLWLLRDKK
>NZ_CP016592.1|WP_013384837.1|2140251_2141100_+|carbohydrate-ABC-transporter-permease
MSASTELAANRRNIRPGRVIAWTLLILGGFLMALPILYMFSTSLKPASDTFDLRLIPAAPTLANYIDILQDGRFIRWFYNSMIIAVAVTASNVFFDSLVGYTLAKFDFRGKNIVFIAILSTLMIPTEMLVIPWYMMSAKLGWLDSHWGIMFPGMMTAFGTFLMKQFFEGVPNDFLEAARVDGLNEFTIWWKIAMPMVLPAISALAIFTFLGNWTAFLWPLISTTSPDLYTLPVGLNSFAVGEAVRWERIMTGAALATIPTLLVFLALQRFIVRGVMLAGLKG
>NZ_CP016592.1|WP_013384838.1|2141103_2142621_+|argininosuccinate-lyase
MSNPNDPRLTDGSVFPDPVYKETVLRPLFDGAKTHHVAAFGAIDRAHLVMLAETGILPAADAGKIAVARAALDTEIDPATLTYTGEVEDYFFLIEKELKARVGAELGGRLHTARSRNDIDHTLFKLGLRARLNLLIEQAIALHGAIVAKAEAESATLIVAYTHGQPAQPSTLGHYLSAMAEILARDIQRLFEAYRIVNLSPMGAAAITTSGFPINRERVAELLGFAAPLQNSYSCIASVDYITSTYSAMELMFLHLGRPIQDLQFWTSFEVGQIYVPNALVQISSIMPQKRNPVPIEHLRHLASQTVGRAHSMLTIMHNTPFTDMNDSEGETQETGYQAFEVAGRVLTLLAALVAQIKVDPARVASNIRRSCITITELADSTVRREGLSFREGHEIAAAVARAVVAAEGDLTTDGYAPFVTAFKHATGRDPQIDAAAFAQITSPEYFVAVRDRTGGPAPEALAQAISGYKTQNAGFAAQLATLIATQSAADADLATAFNLLKESA
>NZ_CP016592.1|WP_013384839.1|2142620_2143682_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MAKIELEGLVKDYGKVRAVHGIDLQIEDGEFVVFVGPSGCGKSTTLRMIAGLEDISGGALKIGGKVVNQLEPKQRNIAMVFQNYAIYPHMTVGQNIAFGLYTSKLPKAEKDRLVREAGETLGLTPYLDRRPAALSGGQRQRVAIGRAMVRSPSAFLFDEPLSNLDAQLRGQMRIEIKRLHQRLGTTIVYVTHDQVEAMTMADKIVVMRDGRILQVGSPLDLYENPVDVFTARFIGSPSMNVIEGESDGVNLRLGNSTLPGFGANLPAGKVMVGLRPHDLKVGVPGDATLEAVVTAIEPLGAETLVHMEVAGQPLVGSAPGRVLPVVGSTVTASVTRGVLYVFDAQTEKALGRA
>NZ_CP016592.1|WP_013384840.1|2143678_2144584_+|ribokinase
MTSKNNGEGVLSLGRIYADLAFAELDAPPTPGREVYAQSFSLTPGGGAVITAAHLVAAGRPAHLLARLGTDPIAVAIASELTALDLDLTYVERAADAGPQLTVAIVTPEDRAFITRRSPRGMPSQAAAALHGAGLRHLHIAEYATLAENPALIVTAKMAGLTISLDPSWDESLIHGPALLAASSGVDVFFPNMDEATALTGKTAPAAALDILAQHFPVVALKCGSAGAMLAVGSTRFSVTAPKTVVVDTIGAGDSFNAGFLDAWLSGLAPEEVLRRAVQRGSQSVMAAGGTGCLSQMKSAS
>NZ_CP016592.1|WP_013384841.1|2144596_2145940_-|Ktr-system-potassium-transporter-B
MKTAVKGWAARFLSLPPPLVVAGIYIATITMGASLMMLPMAQAMPMRWSDAFFMATSAVTVTGLAVVDVGSHLSLLGQAVLVTLVQLGGLGLMTFAVLILEIVGRPVGLMGEAYLREDLKQNALWRVGRLVRRIAVVVFAIEAVGIAILCLSFIPDLGFWPGLWAAIFHGIGAFNNAGFSIFRTGLMEYVADPIVNLVIPALFITGGIGYFVLHDLIYKRRWRYWSLNTRIMLAGTAVLIPWSVLMFAALEWTNPATLGGLDGIWPRIAASWFQGVTPRTAGFNTLDISGIHDSTAMLFISLMLIGGGATSTAGGIKVTTFVVMILATIAFFRRQTQLHIFGRGIGPDEVLKVMAIVAVSLVLVFCGVFLLSLSHDGHFLDIAFEVASAFSTTGLSRNYTPELNDFGRCVIMVIMFIGRLGPLTLGFFLATQLSPRVRYPQERIHIG
>NZ_CP016592.1|WP_013384842.1|2145943_2146606_-|TrkA-family-potassium-uptake-protein
MARTEQSFVVIGLGAFGAAVASELARFGNRVMGIDLDERRVAQMVSVLPTALILDATDEIALREAGVDRYDVALVAIGQNIEASILATMNLRLLGLETVWVKAASRVHHRILVKIGADRVILPEQEMGRHIAQMLNNPVVQDYVSLGNGFNVVSIELPKALDGATPKSLGLVGREEPRLMAAMRGTQQLDIANPDLRFAPNDKLILLGRRVVLQAFSDGL
>NZ_CP016592.1|WP_013384843.1|2146720_2147068_-|hypothetical-protein
MIATSAFAQAPAMPDMDEAVAAANNQLGVLEYCAAEGHIESTAVEVQERLLQVLPPASDPTAVEAAYAAGKEGTIAVSGTEMSLADAATGQGTDVAALCQQLGSMVEQAGASLPN
>NZ_CP016592.1|WP_013384844.1|2147692_2147845_+|hypothetical-protein
MSLINQTVGLGWWSNIAMVRYVEGSMFLRATMDVPHGRRIYQSGMIRLPS
>NZ_CP016592.1|WP_013384845.1|2148319_2148526_-|hypothetical-protein
MNTAPFVRIALRYIAGGLVSYGILTPEGATAFASDPQVIAQASIVLGAATAALTEGFYALAKRWGWRT

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NC_017903	Escherichia coli Xuzhou21 plasmid pO157_Sal, complete sequence	24723-24756	6	0.824
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NC_011148	Salmonella enterica subsp. enterica serovar Agona str. SL483 plasmid, complete sequence	37052-37085	7	0.794
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_KU963390	Escherichia coli strain ECO37 plasmid ECO37P2, complete sequence	30385-30418	7	0.794
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_CP010193	Escherichia coli strain M8 plasmid B, complete genome	33332-33365	7	0.794
NZ_CP016592_1	1.6\|1851679\|33\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851679-1851711	33	NZ_AP022566	Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence	45464-45496	7	0.788
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_CP049247	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed1, complete sequence	18758-18791	8	0.765
NZ_CP016592_1	1.10\|1851952\|34\|NZ_CP016592\|PILER-CR	1851952-1851985	34	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	539756-539789	8	0.765
NZ_CP016592_1	1.14\|1851945\|34\|NZ_CP016592\|CRISPRCasFinder,CRT	1851945-1851978	34	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	539756-539789	8	0.765
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_CP019707	Pantoea alhagi strain LTYR-11Z plasmid pPALTYR11Z, complete sequence	62089-62122	9	0.735
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_CP007740	Bacillus methanolicus MGA3 plasmid pBM69, complete sequence	16414-16447	9	0.735
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_LT222315	Pseudomonas cerasi isolate Sour cherry (Prunus cerasus) symptomatic leaf plasmid p58T3	108477-108510	10	0.706
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_LT963398	Pseudomonas cerasi isolate PL963 plasmid PP3, complete sequence	75521-75554	10	0.706
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	CP034538	Pseudomonas poae strain CAP-2018 plasmid unnamed	107853-107886	10	0.706
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NC_008738	Marinobacter hydrocarbonoclasticus VT8 plasmid pMAQU01, complete sequence	62733-62766	10	0.706
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NC_007678	Salinibacter ruber DSM 13855 plasmid pSR35, complete sequence	14814-14847	10	0.706
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	821-854	10	0.706
NZ_CP016592_1	1.16\|1851811\|35\|NZ_CP016592\|CRT	1851811-1851845	35	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	984065-984099	10	0.714
NZ_CP016592_1	1.5\|1851613\|34\|NZ_CP016592\|PILER-CR,CRISPRCasFinder,CRT	1851613-1851646	34	NZ_CP029542	Streptomyces sp. NEAU-S7GS2 plasmid unnamed1, complete sequence	9497-9530	11	0.676

1. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NC_017903 (Escherichia coli Xuzhou21 plasmid pO157_Sal, complete sequence) position: , mismatch: 6, identity: 0.824

tcccata-aaaaaacccgcctctaagggcgggctg	CRISPR spacer
-gcgacacaaaaaacccgcctctaagggcgggtta	Protospacer
  * *.* ************************.*.

2. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NC_011148 (Salmonella enterica subsp. enterica serovar Agona str. SL483 plasmid, complete sequence) position: , mismatch: 7, identity: 0.794

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
cgacacaaaaaaacccgcctctaaggacgggtta	Protospacer
.  **.********************.****.*.

3. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KU963390 (Escherichia coli strain ECO37 plasmid ECO37P2, complete sequence) position: , mismatch: 7, identity: 0.794

-tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
gcttcat-aaaaaacccgcctctaaaggcgggtta	Protospacer
 ...*** *****************.******.*.

4. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010193 (Escherichia coli strain M8 plasmid B, complete genome) position: , mismatch: 7, identity: 0.794

-tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
gcttcat-aaaaaacccgcctctaaaggcgggtta	Protospacer
 ...*** *****************.******.*.

5. spacer 1.6|1851679|33|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022566 (Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence) position: , mismatch: 7, identity: 0.788

tgcttccg--gtaaaactccaccgcagcgtggaac	CRISPR spacer
--ccgccgacgtgaaacaccaccgcagcgtggaag	Protospacer
  *. ***  **.**** ****************

6. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049247 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
gggcaacaaaaaacccgcctcgaggggcgggctt	Protospacer
   **  ************** *.*********

7. spacer 1.10|1851952|34|NZ_CP016592|PILER-CR matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.765

cccagcaggcgcggcgcagacgacaggcgggacg	CRISPR spacer
atcgacgggcgcggcgcagacgacaggcaagacc	Protospacer
 .*..*.*********************..***

8. spacer 1.14|1851945|34|NZ_CP016592|CRISPRCasFinder,CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.765

cccagcaggcgcggcgcagacgacaggcgggacg	CRISPR spacer
atcgacgggcgcggcgcagacgacaggcaagacc	Protospacer
 .*..*.*********************..***

9. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019707 (Pantoea alhagi strain LTYR-11Z plasmid pPALTYR11Z, complete sequence) position: , mismatch: 9, identity: 0.735

tcccataa------aaaaacccgcctctaagggcgggctg	CRISPR spacer
------aaaggcttaaaaaaccgcctctaagggcggtctt	Protospacer
      **      ***** **************** **

10. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007740 (Bacillus methanolicus MGA3 plasmid pBM69, complete sequence) position: , mismatch: 9, identity: 0.735

tcccataaaaaaacccgcctctaagg-gcgggctg	CRISPR spacer
aaccataaaaatacccccctctaaggtgtttgtt-	Protospacer
  ********* **** ********* *.  *.*

11. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT222315 (Pseudomonas cerasi isolate Sour cherry (Prunus cerasus) symptomatic leaf plasmid p58T3) position: , mismatch: 10, identity: 0.706

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
caaaacgaaaaaacccgcctattagggcgggttt	Protospacer
.   *..************* * ********.*

12. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963398 (Pseudomonas cerasi isolate PL963 plasmid PP3, complete sequence) position: , mismatch: 10, identity: 0.706

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
caaaacgaaaaaacccgcctattagggcgggttt	Protospacer
.   *..************* * ********.*

13. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to CP034538 (Pseudomonas poae strain CAP-2018 plasmid unnamed) position: , mismatch: 10, identity: 0.706

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
acttcacaaaaaacccgcctttaatggcgggttt	Protospacer
 *..   *************.*** ******.*

14. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NC_008738 (Marinobacter hydrocarbonoclasticus VT8 plasmid pMAQU01, complete sequence) position: , mismatch: 10, identity: 0.706

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
agaaaacaaaaaacccgcctcaatgggcgggttt	Protospacer
    *  ************** * *******.*

15. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NC_007678 (Salinibacter ruber DSM 13855 plasmid pSR35, complete sequence) position: , mismatch: 10, identity: 0.706

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
agtcagtaaaaaacccgcctttacgggcggggca	Protospacer
  .**  *************.** ******* ..

16. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 10, identity: 0.706

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
gaaaaataaaaaacccgcctcaaaaggcggggtc	Protospacer
    *  ************** **.****** *

17. spacer 1.16|1851811|35|NZ_CP016592|CRT matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.714

gcgaccaatggcgcgtagcgacaccctatcaggac	CRISPR spacer
acgacgaatggcgcgtcgcgacacccatctgcaac	Protospacer
.**** ********** *********  ... .**

18. spacer 1.5|1851613|34|NZ_CP016592|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029542 (Streptomyces sp. NEAU-S7GS2 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.676

tcccataaaaaaacccgcctctaagggcgggctg	CRISPR spacer
cgtaacgaaaaaacccgcctcggagggcgggact	Protospacer
. . *..************** .******** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

566367 : 574800

Synechococcus_phage(50.0%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013383420.1\|566367_568674_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A291L9W9	Bordetella_phage	3.3e-12	38.0
WP_013383421.1\|568684_569038_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_013383422.1\|569459_570050_+	NYN domain-containing protein	NA	NA	NA	NA
WP_014537458.1\|570125_571076_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_013383423.1\|571077_571542_+	ribonuclease HI	J9Q745	Salmonella_phage	1.6e-35	52.1
WP_013383424.1\|571602_572487_+	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	9.0e-11	37.3
WP_013383425.1\|572483_572855_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_013383426.1\|572851_573748_-\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	2.1e-07	31.0
WP_013383427.1\|573747_574239_-	peptide deformylase	K4JRM9	Caulobacter_phage	1.1e-13	36.4
WP_014537459.1\|574239_574800_-	peptide deformylase	E3SLL2	Synechococcus_phage	3.7e-26	47.9

DBSCAN-SWA_2

1085621 : 1098652

Paracoccus_phage(33.33%)

capsid,head,tail,portal,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049776461.1\|1085621_1086962_+	DNA-packaging protein	A0A0K1LMR9	Caulobacter_phage	4.6e-67	36.5
WP_013383945.1\|1087053_1088217_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	7.6e-58	38.8
WP_013383946.1\|1088203_1088425_+	hypothetical protein	NA	NA	NA	NA
WP_013383947.1\|1088425_1088953_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	3.3e-29	53.7
WP_013383948.1\|1088961_1090092_+\|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	8.1e-65	38.8
WP_014537610.1\|1090156_1090681_+	hypothetical protein	NA	NA	NA	NA
WP_013383951.1\|1090677_1091010_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_014537611.1\|1091006_1091393_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013383953.1\|1091404_1091821_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_013383954.1\|1091817_1092135_+	gene transfer agent family protein	NA	NA	NA	NA
WP_013383955.1\|1092139_1092340_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_013383956.1\|1092332_1092944_+\|tail	phage tail tape measure protein	E7EKW4	Edwardsiella_phage	4.9e-08	55.9
WP_013383957.1\|1092956_1093589_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	2.6e-52	47.1
WP_013383958.1\|1093585_1094431_+	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	1.7e-46	38.8
WP_013383959.1\|1094427_1094841_+	peptidase P60	F4YXU4	Roseobacter_phage	3.3e-16	34.1
WP_013383960.1\|1094842_1098652_+	hypothetical protein	A0A0K1LL82	Rhodobacter_phage	4.1e-201	38.0

DBSCAN-SWA_3

1288500 : 1295722

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014537685.1\|1288500_1289178_+	guanylate kinase	A0A143DIC6	Abalone_herpesvirus	7.6e-18	33.3
WP_013384143.1\|1289224_1290259_+	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	4.7e-27	31.1
WP_013384144.1\|1290361_1290961_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.9e-33	40.4
WP_014537686.1\|1291023_1291917_+	EamA family transporter RarD	NA	NA	NA	NA
WP_044008154.1\|1291901_1292456_-	TIGR00730 family Rossman fold protein	A0A2I2L3F0	Orpheovirus	1.3e-12	30.8
WP_014537688.1\|1292605_1293832_+	LysM peptidoglycan-binding domain-containing protein	A0A0A7RVP5	Clostridium_phage	8.4e-07	44.2
WP_013384148.1\|1293901_1295722_+	ABC transporter ATP-binding protein/permease	W8CYL7	Bacillus_phage	3.6e-38	27.6

DBSCAN-SWA_4

2030689 : 2084819

Paracoccus_phage(14.29%)

capsid,terminase,head,tail,portal,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013383011.1\|2030689_2030932_-\|head,protease	prohead protease	A0A1B1IVR9	uncultured_Mediterranean_phage	5.8e-05	47.3
WP_013383009.1\|2031909_2032824_+	hypothetical protein	NA	NA	NA	NA
WP_013383008.1\|2032865_2034467_+	peptide chain release factor 3	A0A2K9L6L3	Tupanvirus	6.0e-13	32.0
WP_014537866.1\|2034521_2035292_-	hypothetical protein	NA	NA	NA	NA
WP_013383006.1\|2035527_2036595_+	hemin-degrading factor	NA	NA	NA	NA
WP_060486268.1\|2036594_2037437_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_060486269.1\|2037441_2038518_+	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	6.8e-13	26.0
WP_013383002.1\|2038514_2039306_+	heme ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.7e-06	26.7
WP_013383001.1\|2039433_2040456_+	phosphate ABC transporter substrate-binding protein	A0A1B1IWY0	uncultured_Mediterranean_phage	9.9e-62	40.6
WP_013383000.1\|2040513_2041893_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_013382998.1\|2043245_2044007_+	phosphate ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_013382997.1\|2044019_2044730_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_013382996.1\|2044733_2045423_+	phosphate regulon transcriptional regulatory protein PhoB	W8CYM9	Bacillus_phage	4.4e-37	35.1
WP_013382995.1\|2045879_2047112_+	MFS transporter	NA	NA	NA	NA
WP_081447077.1\|2047252_2047576_+	hypothetical protein	NA	NA	NA	NA
WP_081447076.1\|2047616_2048189_-	nucleoside 2-deoxyribosyltransferase	NA	NA	NA	NA
WP_013382992.1\|2048212_2048797_-	ATPase AAA	NA	NA	NA	NA
WP_013382991.1\|2048826_2049561_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_013382989.1\|2050299_2051076_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.1e-24	34.3
WP_013382988.1\|2051131_2052190_-	myristoyl transferase	NA	NA	NA	NA
WP_014537869.1\|2052274_2053171_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_065739322.1\|2053242_2054385_+	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	2.5e-82	45.7
WP_013382984.1\|2054381_2054507_-	hypothetical protein	NA	NA	NA	NA
WP_013382983.1\|2054600_2055764_+	Hint domain-containing protein	NA	NA	NA	NA
WP_014537870.1\|2055799_2055982_+	hypothetical protein	NA	NA	NA	NA
WP_013382982.1\|2055994_2056600_+	16S rRNA methyltransferase	NA	NA	NA	NA
WP_013382981.1\|2057081_2057378_-	hypothetical protein	NA	NA	NA	NA
WP_013382980.1\|2057444_2057852_+	hypothetical protein	A0A291AUP1	Sinorhizobium_phage	2.5e-16	39.0
WP_013382979.1\|2057858_2058056_+	hypothetical protein	NA	NA	NA	NA
WP_013382978.1\|2058288_2059491_+	Hint domain-containing protein	NA	NA	NA	NA
WP_014537871.1\|2059522_2059729_-	hypothetical protein	NA	NA	NA	NA
WP_013382976.1\|2059870_2060074_-	hypothetical protein	NA	NA	NA	NA
WP_014537872.1\|2060070_2060499_-	carboxypeptidase	K4I3B7	Acinetobacter_phage	1.2e-24	49.2
WP_013382974.1\|2061040_2061769_+	Hint domain-containing protein	NA	NA	NA	NA
WP_013382973.1\|2061802_2062099_-	hypothetical protein	NA	NA	NA	NA
WP_156771220.1\|2062183_2062342_+	hypothetical protein	NA	NA	NA	NA
WP_014537873.1\|2062362_2063667_-	hypothetical protein	NA	NA	NA	NA
WP_014537874.1\|2063666_2063930_-	hypothetical protein	I3UM19	Rhodobacter_phage	1.9e-09	46.9
WP_014537875.1\|2064035_2064350_-	H-NS histone family protein	NA	NA	NA	NA
WP_013384754.1\|2064502_2064772_-	hypothetical protein	NA	NA	NA	NA
WP_014537876.1\|2064773_2065925_-	hypothetical protein	NA	NA	NA	NA
WP_013384756.1\|2065921_2066326_-	hypothetical protein	NA	NA	NA	NA
WP_013384757.1\|2066540_2067122_+	sugar O-acetyltransferase	NA	NA	NA	NA
WP_013384758.1\|2067130_2067556_-	hypothetical protein	M1PRG4	Prochlorococcus_phage	1.3e-07	46.7
WP_013384759.1\|2067558_2071065_-	hypothetical protein	A0A0U2C146	Paracoccus_phage	3.6e-87	34.1
WP_013384760.1\|2071066_2071495_-	hypothetical protein	A0A0U2C0Z1	Paracoccus_phage	2.1e-18	39.6
WP_014537877.1\|2071473_2072100_-	hypothetical protein	NA	NA	NA	NA
WP_013384762.1\|2072188_2072518_+	hypothetical protein	NA	NA	NA	NA
WP_013384763.1\|2072518_2073169_-	hypothetical protein	NA	NA	NA	NA
WP_013384765.1\|2076202_2076349_-	hypothetical protein	NA	NA	NA	NA
WP_013384766.1\|2076381_2076765_-	gene transfer agent family protein	A0A141GEX0	Brucella_phage	9.9e-07	33.3
WP_013384767.1\|2076764_2077223_-	hypothetical protein	NA	NA	NA	NA
WP_014537878.1\|2077263_2077461_-	hypothetical protein	NA	NA	NA	NA
WP_013384768.1\|2077453_2077864_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013384769.1\|2077863_2078259_-	hypothetical protein	NA	NA	NA	NA
WP_013384770.1\|2078272_2078620_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_013384771.1\|2078616_2079144_-\|head,tail	phage gp6-like head-tail connector protein	A0A141GEW4	Brucella_phage	5.0e-09	26.5
WP_013384772.1\|2079194_2080373_-\|capsid	phage major capsid protein	Q6JIM7	Burkholderia_virus	5.7e-53	35.7
WP_013384773.1\|2080395_2081049_-\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	3.3e-34	42.7
WP_014537879.1\|2081058_2082219_-\|portal	phage portal protein	B4UTP1	Rhizobium_phage	3.4e-10	24.5
WP_013384775.1\|2082215_2083997_-\|terminase	phage terminase large subunit	B0VK29	Azospirillum_phage	1.0e-138	44.3
WP_014537880.1\|2083959_2084370_-	hypothetical protein	NA	NA	NA	NA
WP_014537881.1\|2084504_2084819_-	HNH endonuclease	A0A286N2R3	Klebsiella_phage	1.8e-06	43.6

DBSCAN-SWA_5

2092027 : 2098098

EBPR_podovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013384783.1\|2092027_2092312_-	DUF2312 domain-containing protein	A0A1X9HX62	Ruegeria_phage	3.1e-21	68.9
WP_014537887.1\|2092308_2092569_-	hypothetical protein	NA	NA	NA	NA
WP_013384784.1\|2092565_2093147_-	DNA methyltransferase	F8TVB4	EBPR_siphovirus	6.2e-45	49.2
WP_013384785.1\|2093143_2093374_-	hypothetical protein	NA	NA	NA	NA
WP_044008065.1\|2093370_2093601_-	hypothetical protein	NA	NA	NA	NA
WP_014537888.1\|2093597_2093849_-	hypothetical protein	F8TUW5	EBPR_podovirus	1.1e-19	72.3
WP_014537889.1\|2093847_2094207_+	helix-turn-helix transcriptional regulator	F8TUW4	EBPR_podovirus	3.7e-32	75.0
WP_014537890.1\|2094449_2095502_+	restriction endonuclease or methylase	A0A1S5SAB0	Streptococcus_phage	7.1e-63	40.6
WP_013384786.1\|2095728_2095959_+	hypothetical protein	NA	NA	NA	NA
WP_013384787.1\|2095969_2096227_+	acyl carrier protein	NA	NA	NA	NA
WP_013384788.1\|2096223_2096409_+	hypothetical protein	NA	NA	NA	NA
WP_013384789.1\|2096405_2096711_+	hypothetical protein	NA	NA	NA	NA
WP_013384790.1\|2096707_2096968_+	acyl carrier protein	NA	NA	NA	NA
WP_013384791.1\|2096964_2098098_+	DNA polymerase III subunit beta	A0A0A8IL17	Aurantimonas_phage	7.4e-26	30.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP016592

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection