CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	1 crisprs	csa3	0	1	1	0
NZ_CP016559	Streptomyces clavuligerus strain F613-1 chromosome, complete genome	19 crisprs	DEDDh,csa3,DinG,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,WYL,cas2,cas1,cas4,cas6,RT	2	7	1	0

1. NZ_CP016559

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016559_1

• CRISPR_ID: NZ_CP016559_1
• CRISPR_location: 1136326-1136447
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_1

Consensus_repeat	Method
GTGAGCCGAAGGGGTGCCGCGGGTGCCGGAAGTGGAG	CRISPRCasFinder

spacers of NZ_CP016559_1

>1.1|1136363|48|NZ_CP016559|CRISPRCasFinder
GACGCCTGGCCGCCTCCTGGGCCGGGCGTTGCCTCCACCCCGGGGCGA

CRISPR arrays and Neighbor proteins around NZ_CP016559_1

CRISPR arrays

The CRISPR arrays of NZ_CP016559_1

>merge|NZ_CP016559|1|1136326-1136447|CRISPRCasFinder
GTGAGCCGAAGGGGTGCCGCGGGTGCCGGAAGTGGAGGACGCCTGGCCGCCTCCTGGGCCGGGCGTTGCCTCCACCCCGGGGCGAGTGAGCCGAAGGGGTGCCGCGGGTGCCGAAAGTGGAG

>NZ_CP016559|1|1|1136326-1136447|CRISPRCasFinder
GTGAGCCGAAGGGGTGCCGCGGGTGCCGGAAGTGGAG	GACGCCTGGCCGCCTCCTGGGCCGGGCGTTGCCTCCACCCCGGGGCGA
GTGAGCCGAAGGGGTGCCGCGGGTGCCGAAAGTGGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003962237.1|1133940_1135575_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|183199
NZ_CP016559.1|WP_003962236.1|1136759_1138157_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|225822
NZ_CP016559.1|WP_003962243.1|1128989_1129580_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP016559.1|WP_003962240.1|1130956_1131352_+|glyoxalase	unknown	unknown	gnl|CDD|319901
NZ_CP016559.1|WP_003958158.1|1141286_1141985_+|phosphoadenylyl-sulfate-reductase	unknown	unknown	gnl|CDD|234997
NZ_CP016559.1|WP_003958152.1|1145084_1146191_+|aliphatic-sulfonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|130789
NZ_CP016559.1|WP_003962242.1|1129818_1130037_+|CbtB-domain-containing-protein	unknown	unknown	gnl|CDD|370526
NZ_CP016559.1|WP_003958166.1|1132704_1133835_-|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085
NZ_CP016559.1|WP_003962239.1|1131875_1132574_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197666
NZ_CP016559.1|WP_003962245.1|1125190_1127917_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|225827
NZ_CP016559.1|WP_003958161.1|1139243_1140941_+|nitrite/sulfite-reductase	unknown	unknown	gnl|CDD|223233
NZ_CP016559.1|WP_003958155.1|1142586_1143540_+|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl|CDD|235375
NZ_CP016559.1|WP_003962235.1|1138162_1138744_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP016559.1|WP_009997832.1|1123393_1125049_+|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|366675
NZ_CP016559.1|WP_003958154.1|1143542_1144877_+|sulfate-adenylyltransferase	unknown	unknown	gnl|CDD|180120
NZ_CP016559.1|WP_003962244.1|1128179_1128971_+|hypothetical-protein	unknown	unknown	gnl|CDD|235244
NZ_CP016559.1|WP_003958159.1|1141110_1141290_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003962233.1|1141981_1142560_+|adenylyl-sulfate-kinase	unknown	unknown	gnl|CDD|238985
NZ_CP016559.1|WP_003962241.1|1130058_1130826_+|CbtA-family-protein	unknown	unknown	gnl|CDD|378192
NZ_CP016559.1|WP_003962230.1|1146317_1147106_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213260

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003962237.1|1133940_1135575_+|acyl-CoA-dehydrogenase	gnl|CDD|183199	PRK11561, PRK11561, isovaleryl CoA dehydrogenase; Provisional.	2.55112e-171
NZ_CP016559.1|WP_003962236.1|1136759_1138157_+|GAF-domain-containing-protein	gnl|CDD|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	1.88105e-39
NZ_CP016559.1|WP_003962243.1|1128989_1129580_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.62767e-25
NZ_CP016559.1|WP_003962240.1|1130956_1131352_+|glyoxalase	gnl|CDD|319901	cd07235, MRD, Mitomycin C resistance protein (MRD). Mitomycin C (MC) is a naturally occurring antibiotic, and antitumor agent used in the treatment of cancer. Its antitumor activity is exerted primarily through monofunctional and bifunctional alkylation of DNA. MRD binds to MC and functions as a component of the MC exporting system. MC is bound to MRD by a stacking interaction between a His and a Trp. MRD adopts a structural fold similar to bleomycin resistance protein, glyoxalase I, and extradiol dioxygenases; and it has binding sites at an identical location to binding sites in these evolutionarily related enzymes.	5.51526e-58
NZ_CP016559.1|WP_003958158.1|1141286_1141985_+|phosphoadenylyl-sulfate-reductase	gnl|CDD|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.76993e-111
NZ_CP016559.1|WP_003958152.1|1145084_1146191_+|aliphatic-sulfonate-ABC-transporter-substrate-binding-protein	gnl|CDD|130789	TIGR01728, Putative_aliphatic_sulfonates-binding_protein, ABC transporter, substrate-binding protein, aliphatic sulfonates family. Members of this family are substrate-binding periplasmic proteins of ABC transporters. This subfamily includes SsuA, a member of a transporter operon needed to obtain sulfur from aliphatic sulfonates. Related proteins outside the scope of this model include taurine (NH2-CH2-CH2-S03H) binding proteins, the probable sulfate ester binding protein AtsR, and the probable aromatic sulfonate binding protein AsfC. All these families make sulfur available when Cys and sulfate levels are low. Please note that phylogenetic analysis by neighbor-joining suggests that a number of sequences belonging to this family have been excluded because of scoring lower than taurine-binding proteins. [Transport and binding proteins, Other].	9.33824e-52
NZ_CP016559.1|WP_003962242.1|1129818_1130037_+|CbtB-domain-containing-protein	gnl|CDD|370526	pfam09489, CbtB, Probable cobalt transporter subunit (CbtB). This entry represents a family of proteins which have been proposed to act as cobalt transporters acting in concert with vitamin B12 biosynthesis systems. Evidence for this assignment includes 1) prediction of a single transmembrane segment and a C-terminal histidine-rich motif likely to be a metal-binding site, 2) positional gene linkage with known B12 biosynthesis genes, 3) upstream proximity of B12 transcriptional regulatory sites, 4) the absence of other known cobalt import systems and 5) the obligate co-localization with a protein (CbtA) predicted to have five additional transmembrane segments.	0.000293823
NZ_CP016559.1|WP_003958166.1|1132704_1133835_-|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	1.68691e-44
NZ_CP016559.1|WP_003962239.1|1131875_1132574_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.84091e-09
NZ_CP016559.1|WP_003962245.1|1125190_1127917_+|SpoIIE-family-protein-phosphatase	gnl|CDD|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	9.93115e-61
NZ_CP016559.1|WP_003958161.1|1139243_1140941_+|nitrite/sulfite-reductase	gnl|CDD|223233	COG0155, CysI, Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism].	1.62981e-174
NZ_CP016559.1|WP_003958155.1|1142586_1143540_+|sulfate-adenylyltransferase-subunit-CysD	gnl|CDD|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP016559.1|WP_003962235.1|1138162_1138744_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.56808e-09
NZ_CP016559.1|WP_009997832.1|1123393_1125049_+|FAD-dependent-monooxygenase	gnl|CDD|366675	pfam01494, FAD_binding_3, FAD binding domain. This domain is involved in FAD binding in a number of enzymes.	1.54875e-121
NZ_CP016559.1|WP_003958154.1|1143542_1144877_+|sulfate-adenylyltransferase	gnl|CDD|180120	PRK05506, PRK05506, bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Provisional.	0
NZ_CP016559.1|WP_003962244.1|1128179_1128971_+|hypothetical-protein	gnl|CDD|235244	PRK04182, PRK04182, cytidylate kinase; Provisional.	3.26181e-05
NZ_CP016559.1|WP_003962233.1|1141981_1142560_+|adenylyl-sulfate-kinase	gnl|CDD|238985	cd02027, APSK, Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of inorganic sulfate.	2.67078e-78
NZ_CP016559.1|WP_003962241.1|1130058_1130826_+|CbtA-family-protein	gnl|CDD|378192	pfam09490, CbtA, Probable cobalt transporter subunit (CbtA). This entry represents a family of proteins which have been proposed to act as cobalt transporters acting in concert with vitamin B12 biosynthesis systems. Evidence for this assignment includes 1) prediction of five transmembrane segments, 2) positional gene linkage with known B12 biosynthesis genes, 3) upstream proximity of B12 transcriptional regulatory sites, 4) the absence of other known cobalt import systems and 5) the obligate co-localization with a small protein (CbtB) having a single additional transmembrane segment and a C-terminal histidine-rich motif likely to be a metal-binding site.	5.87678e-51
NZ_CP016559.1|WP_003962230.1|1146317_1147106_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.75653e-112

Protein sequences

>NZ_CP016559.1|WP_003962237.1|1133940_1135575_+|acyl-CoA-dehydrogenase
MAASTHTVTNQAPPLVGYDVFTADRALAEAVERHVPAESAAVAAAELSALGRTAGSAEAQEWGALANEYPPRLRTHDRYGNRIDEVEFHPAWHRLLGHAVRAGLTDAWGRPSGHVRRAAGFLVWTQAEAGHGCPLSMTHAAVPALRTDPELAAEWEPRLTAHTYDGTLAVPASKPGNLFGMGMTEKQGGSDVRANTTAATPLAAAGEYVLTGHKWFCSAPMSDGFLVLAQAPGGLTCFLVPRVLPDGGRNVFRLQRLKDKLGNRSNASAEVEFEGTWARRVGEEGRGVRTIIEMVAATRLDCVIGSAALMRQAVARAIHHTAHRGAFGGLLIDKPLMRNVLADLALESEAATALGIRLAAAYDAGTEAERAFARIAVPAAKYWVTKRCAPTAAEALECLGGNGYVEESGMPRLLREAPLNSIWEGSGNVQALDVLRALQREPAALNAFLQEVGLARGADHRLDGAIKGLLTELADLDGIEARARRLVERMALVLQGSLLVRYAPPEVADAFCASRLGGDRGAAFGTLPHTLALRAVVERARPVH
>NZ_CP016559.1|WP_003958166.1|1132704_1133835_-|YihY/virulence-factor-BrkB-family-protein
MTWLLLKDTVNSCIEYRILGLAAEAAFFTLLSLPPLMLGLLGLLGYIDDWTNTTTVASIEQNILNAAGTVLSERGVNDVARPLLEDVTHGGRPDLISIGFAIALWSGSRAVNVFIDTITVMYGLDGRRGIVATRLLAFLLYLIALVIGAVVLPLAVVGPDRVVEWVPWGTTLVTVLYWPVVILLSVAFLTTLYHVSVPVRSPWIEDVPGALVALGMWVLGSFLLRIYLVSTVEGPTIYGSLAAPIAVLLWIGISAFAILVGAAVNAAIDRVWPSVATAAARAEGDRRRAAEAAEVLARARAARIFEEMEGSPDEEGDDWDEDDSVGGDGEMPSEFPERWSRFLPPEDIRSRLHTHRAHHPKTPPNGHQGPPGPPGD
>NZ_CP016559.1|WP_003962239.1|1131875_1132574_-|helix-turn-helix-transcriptional-regulator
MYRERVSRLPGAVVWEVVRSDGGPVLPDGCVDILWTPGELLVAGPDTRAQHGDGRPPGIRWAGVRFAPGTAPAVLGVPAHELRDRRVPWAALWGDAAARALVARLDAAFDPVAELERIALRAAADAPRPPDPLTAEVVRALAAGSTVAAVAESTGLGARRLHRRSLHAFGYGPKTLARVLRLQRALTLIHRGAPYATAAATAGCADQAHLAREMRALGGMTLSEWSRHRGLA
>NZ_CP016559.1|WP_003962240.1|1130956_1131352_+|glyoxalase
MTPQLDAIGIVTSDLPASLAFYRRLGLDIPAGAESAPHVEVTLPGGTRVLWDTEETVRSFDPSWTRPEGGDRTALAFRCADPAEVDAVYAGLTAAGHRGHLAPWDAAWGQRYAVVLDPDGLGVQLFANTEA
>NZ_CP016559.1|WP_003962241.1|1130058_1130826_+|CbtA-family-protein
MNSTSVRALLVRGMLAGLVAGAAALLVAYFLGEGPVDAAIAFEEANSHEHGGDAPVSRAVQATAGLATGVLVFGVAIGGIAALAHCVALGRIGRFGPRATAALVALGALVTVYVVPYLKYPPNPPAVGDPGTIGQRTALYFLMVVLSVLLAVAAVLLGQRLAPGLGNGNAAVAAVAAFVVAVGLAFAFLPSFDEVPKGFPATVVWEFRLATLAVHTTLWAVYGLVFGLLAERLLTPGTAASASGRGGARTPAARR
>NZ_CP016559.1|WP_003962242.1|1129818_1130037_+|CbtB-domain-containing-protein
MAQTTAPAPAAAPAITPISLREIAPWAAFFGVLMLILLYFVGAEQGATAVFAGDTVHEWVHDGRHLLGFPCH
>NZ_CP016559.1|WP_003962243.1|1128989_1129580_-|histidine-phosphatase-family-protein
MTAKAAGTLRLALITPAVNAALREARFAADVPLDPAGSAAARAAAGALPPAGRALAGPSLRCRETAEALGLAAEPVPALADWGMGRWQGRTLAEVSAAEPEGVARWLSDPSAAPHGGDPLTALIARAGTWLDALPPGGGRLLAVVDPAVVRALLVHALDLPAAVFWRLDPAPLTLTGLTSRAGRWNLHCGTRLLAP
>NZ_CP016559.1|WP_003962244.1|1128179_1128971_+|hypothetical-protein
MRALWIGGPPAAGKTTVARLLARRRGLRRYSADAHTWSHRDRALAAGHPAAVRWEALPRAERWAAPPAELLAMSLHHERGPMVADDVRALPAAPPAVVEGTPVTPSVAGVGRHALWLLPTRRVQRERLAERGLDPGPLALYAQLVDTIEDEVERYGGAVLRVDGRRSVEETLAEVERHFGDALAAGAASAEERGALLRYANGALAEQYRAFAARPWAPGDATATVLGFACECGAPACAADVPLSVRAYGTGPALAPGHRAPQR
>NZ_CP016559.1|WP_003962245.1|1125190_1127917_+|SpoIIE-family-protein-phosphatase
MAARYGRPRSVLRMRTVAGQVFLLQVVIVLLLVAAGIVALVLQAHADSEREAVHRSESVASTFASAPGVAAALRSPDPTALLQPSAEEARRRSEVDFISVLSTEGIRYTHPAPDGIGKKFIGDFTPALHGEVVTQQLTGSIGEIVQAVVPVWGPDRKVVGLVAAGVTISKVNTVVEDQFPLLFGVSAVVLLLTTGGTALVTRRLRRQTHGLGPEEMTRMYEHHDAVLHAVREGVLIVGDGGRLLLVNDEARRLLGLPAAVEGRRVADLGLDPSTARLLASGRVVTDEVHQVGDRLLAVNQRPTDRDGGPPGSVATLRDTTELRALTGRADVARARLKLLYDAGAEIGTTLDVQRTCEELAGFTVGRFADFATVDLVDAVLRGEEPRATGAGEEMRRVAVGGLGDETAHFALGTTIRYLTTTRMGAGLNQGEGILERELPAYDGWQQQSPERAARLVAAGFHSMIAVPLRARGAILGVAMFWRSQTPEPFEEEDRSLAEELVARAAVSVDNARRYSREHTMAVALQRSLLPRTLPEQSALDIASRYRPAQAGAGGLGGVGGDWFDIIPLPGARVALVVGDVVGHGLHAAATMGRLRTAVHNFSTLDLPPDELLWHLDELVARLDQDETGNGAEAGVTGATCLYAIYDPSSGRCTVARAGHLQPLVLRPDGSAFFAEVPGGPPLGLGGMPYETLDVDLPEGSSLVLYTDGLVEDRERDMDEGLDLLRRTVGGHPERTPDEICDAVLGALLPQRPRDDVALLVGRARRLESDRVAEWDVPSDPSAVGEVRSAVTRRLTDWGMGEEAFTTELILSELVTNAIRYAAGPIRVRLIRDRTLICEVSDHSSTSPHLRQAASTDEGGRGLFLVAQFADRWGTRYTVDGKVIWTEQPLSGPDAEAGPESGAQPGAGV
>NZ_CP016559.1|WP_009997832.1|1123393_1125049_+|FAD-dependent-monooxygenase
MQGTAENAKKSETADLRVPILIVGGSLVGLSASMFLSRHGVGHLLVEKHAGTSTHPRGRGINVRSMELFRRAGVERDIRAAAAVLAPNHGILQAASLTGDDQSWLFKEIDPGGGLSRISPASWCLCSQNDIEPVLAKRSAEAGAQLRFGTGLLSFTQDPTGVSALVADRATGERTTVRADYLVAADGPRSPVREALRIGQSGSGELFHNVSLTFTSRGLIDIVGDRRFIVCYLTAPGADGALLPVDNAERWVFHAPWHPERGETLEEFTDERCRQHIRRAVGAPDLDVEITGKAPWHAAERVARRYGAGRVLLAGDAAHEMSPTGAFGSNTGIQDAHNLAWKLAAVLKGWAGQGLIDTYGQERLPVARATGERASARSAEHSHPGYAAPVLPGGPRGGVLTVAMGYGYPAGAVIGVDPARPVVPDRLALTGEPGTRAPHLWVRRDGERLSTLDLYERSMVLLCGEGAVWRDAAHKAAARLSVPLDVYAVGDGPLADLVPEEGCDWTATHGTTAEGALLVRPDGFVAWRSPGGALDPEKAVEEALADILRLR
>NZ_CP016559.1|WP_003962236.1|1136759_1138157_+|GAF-domain-containing-protein
MPTTPLDPPDAVPLDPAETDRLLTRVGAQPPGDGRPAAGPRAEIAESWRRLLRHGLDPGREPRAGLLSRDELERRRQDSPLGEVLDVLRAGLVSASDAARLIMVVADAEGRMLWREGEATVRRKADAHGFVPGADLNEEWIGTNGVGTALITGRPIHVHATEHFLAAHRTWTCAGAPVVDPRDGRPLGVVNVSGPLATVHPTMLALVTSVARLAEAELRRHHFAALERLRSSAAPLLGRMGGRALAVDGDGWTAAVIGMPPPDRLALPKPPPDGRVWLPALGMCAMEPLPGGWLLRPEEAADPGGCAPRVLLDLSRAHRPSVTVRGEEGSWTYEPSPRHAELLCALARHPGGRSAAELAADLFADPSRTVTVRAEFSRLRRHLAPVLASRPYRFADGVEVEVIPPAPGAFPGAPTAAGPGVCPGAVETGSEAAGGCRGVRAAVETGPEVPPAPARLGGEQPGVLP
>NZ_CP016559.1|WP_003962235.1|1138162_1138744_+|GNAT-family-N-acetyltransferase
MSIAVTTWSLEQTSPADLRPAAVPEGDIRIVRSEVPSPEFSRFLYRAVGGDVRWTDRLGMTYAQWEETLGRPGTETWVAYDRGTPAGYAELQAQDEGVVEIVYFGLMPAFRGRRIGGHLLSYATARAWDLAERWPDLPSTKRVWVHTCSLDGPHAMANYERRGFALFDTSVADEPVRETPGPWRGAHPAAPGR
>NZ_CP016559.1|WP_003958161.1|1139243_1140941_+|nitrite/sulfite-reductase
MAATPDKPAPAASRRRTGRHRGEGQWAVGHMTPLNANEQTKKDDDGLNVRTRIETIYAKRGFDSIDGADLRGRMRWWGLYTQRKPGIDGGKTAILEPEELDDEYFMLRVRIDGGRLTTQQLRVIGEISQEFARGTADITDRQNVQYHWIRIEDVPEIWRRLEAVGLSTTEACGDTPRVILGSPVAGIAEDEIIDGTPAIDEIYRRIVGNKDFSNLPRKFKSAISGSPLLDVAHEINDIAFVGVNHPEHGPGFDVWVGGGLSTNPKIGVRLGAWVALEDVPDVYEGVISVFRDYGYRRLRNRARLKFLVADWGAEKFRQVLEEQYLLRKLADGPAPEQPVQRWRDHVGVHRQRDGRYYVGFAPRVGRVDGATLSKIAELAEAHGSGRLRTTAEQKMLVLDIEESQVEPLVAGLEALDLRVTPSPFRRGTMACTGIEFCKLAIVETKGRGASLIDELERRLPDFDEPLTININGCPNACARIQVADIGLKGQLVLDDEGRQVEGYQVHLGGALGLEPGFGRKVRGLKVTSDELPDYVERVVRRFEAEREDGERFAVWAARASEEALS
>NZ_CP016559.1|WP_003958159.1|1141110_1141290_+|hypothetical-protein
MSERAAPFYCPYCGDEDLRPSEEGHGAWECAACNRAFRLKFLGLLARGVARAEVTEEGI
>NZ_CP016559.1|WP_003958158.1|1141286_1141985_+|phosphoadenylyl-sulfate-reductase
MTVVSPEQHRALAERAGRELEDAPALEILSWAAKTFGPRFCVTSSMEDAVVAHLASRAFPGVDVVFLDTGYHFPETIGTRDAVEAVMDVRVITLTPRRSVAEQDAEHGPRLHDRDPDLCCALRKVKPLEEGLTGYDAWATGLRRDESPTRANTPVVGWDERRGKVKVSPIARWTQDDVDAYVAEHGVLTNPLLMDGYTSVGCAPCTRQVLAGEDARAGRWAGRGKTECGLHG
>NZ_CP016559.1|WP_003962233.1|1141981_1142560_+|adenylyl-sulfate-kinase
MTTQARERAKERETHVTGATIWLTGLPSAGKTTIARALAERLAAEGRRTEVLDGDEIREFLSAGLGFDRRDRDTNVQRIGFVAELLASHGVLVLVPVIAPYADSRESVRERHAAEGTPYVEVHVATPVEVCSERDVKGLYARQAAGEISGLTGVDDPYEAPVSPDLRIESQDQSVEESAGALYALLAERGVL
>NZ_CP016559.1|WP_003958155.1|1142586_1143540_+|sulfate-adenylyltransferase-subunit-CysD
MAGGQGAAGAGAQQPEADSPFALSHLDALESEAVHIFREVAGEFERPVILFSGGKDSIVMLHLALKAFAPAAIPFSLLHVDTGHNFPEVLEYRDRTVARHGLRLRIASVQEYIDAGTLRERPDGTRNPLQTVPLTDAIQEHRFDAVFGGGRRDEEKARAKERVFSLRDEFSQWDPRRQRPELWQLYNGRHAPGEHVRVFPLSNWTELDVWQYIARESIELPEIYFAHEREVFSRSGMWLTAGDWGGPRESEPVQTRTVRYRTVGDMSCTGAVDSDATTLDAVIAEIAASRLTERGATRADDKLSEAAMEDRKREGYF
>NZ_CP016559.1|WP_003958154.1|1143542_1144877_+|sulfate-adenylyltransferase
MTSATEQLSATTLLRFATAGSVDDGKSTLVGRLLHDSKSVLTDQLEAVEHASRSRGQEAPDLALLTDGLRAEREQGITIDVAYRYFATARRRFILADTPGHVQYTRNMVTGASTAELAVVLVDARNGVVEQTRRHAAVAALLRVPHVVLAVNKMDLVDYDETVFAAIANEFTGYASALGVPEITAIPISALAGDNVVDPSANMDWYGGPTVLEHLETVPVSHDLTGCHARFPVQYVIRPQTAEHPDYRGYAGQIAAGTFRVGEQVTVLPSGRRSTITGIDLLGRPVDTAWAPQSATLLLADDIDISRGDLLVPSDDAPPTSQDIEATVCHVADRPLTVGQRVLLKHTTRTVKAIVKAIPSRLTLDDLSQHPDPGQLLANDIGRVTVRTAEPLALDPYAQSRRTGSFLLIDPADGTTLTAGMAGEAFTDVTAPTTPADDDAEWDF
>NZ_CP016559.1|WP_003958152.1|1145084_1146191_+|aliphatic-sulfonate-ABC-transporter-substrate-binding-protein
MPAIRTTLRRGAVSAAVLPLLIGALASCGYGSEKDDDSTAPAATGKKLSADAVRLGYFPNLTHATALVGEQEGILQKKLGGTLLKSTTFNAGPSAIEALNAGSIDIGFIGPSPSINGFAKSKGKNLRIVAGSASGGVKLVVNPKKIKTLEDLRGKRIATPQLGNTQDVAFLNWIAEKGWKTDAQSGKGDVLVVRTDNKITPDAYSSGSIDGAWVPEPTASKLVSQGAKVLLDETELWPGKQFVITHLIVAQKFLKEHPDVVEAVVRGTVETNAWIGANPDRAKKSANARLKALTGKPLPAEIIDPAWPSIRFTDDPLAATLKTQADHAVQAGLLKQPELAGIYDLTILNKVLKAAGRPEVSDAGLGIR
>NZ_CP016559.1|WP_003962230.1|1146317_1147106_+|ABC-transporter-ATP-binding-protein
MATATKDQAEERTTASPAARIEHVSKSFATPAGRQLVLDDISLDVAPGEFVTLLGASGCGKSTLLNLVAGLDAPTSGAITTQGRPALMFQEHALFPWLTAGKNIELALRLRGVPKAERRPEAERLLELVRLGGAHRKRVHELSGGMRQRVALARALAQDSQLLLMDEPFAALDAITRDVLHEELTRIWRETRLSVLFVTHNVREAVRLAERVVLLSSRPGRIAREWTVGIEQPRRIEDAAVAELSIEITEELRGEIRRHGQN

Crispr_ID: NZ_CP016559_2

• CRISPR_ID: NZ_CP016559_2
• CRISPR_location: 1194094-1194191
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_2

Consensus_repeat	Method
TGCCCACTCCCCGCACCGAGTGG	CRISPRCasFinder

spacers of NZ_CP016559_2

>2.1|1194117|52|NZ_CP016559|CRISPRCasFinder
CCGTCTCCCCTGGCGGGCCCCGGGGCCGTCCCTCTCCCACCGGGCGGAACTA

CRISPR arrays and Neighbor proteins around NZ_CP016559_2

CRISPR arrays

The CRISPR arrays of NZ_CP016559_2

>merge|NZ_CP016559|2|1194094-1194191|CRISPRCasFinder
TGCCCACTCCCCGCACCGAGTGGCCGTCTCCCCTGGCGGGCCCCGGGGCCGTCCCTCTCCCACCGGGCGGAACTATGCCCACTCCCCGCGCCGAGTGG

>NZ_CP016559|2|2|1194094-1194191|CRISPRCasFinder
TGCCCACTCCCCGCACCGAGTGG	CCGTCTCCCCTGGCGGGCCCCGGGGCCGTCCCTCTCCCACCGGGCGGAACTA
TGCCCACTCCCCGCGCCGAGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003962199.1|1195945_1196647_+|DUF3000-domain-containing-protein	unknown	unknown	gnl|CDD|378665
NZ_CP016559.1|WP_079133002.1|1187673_1189065_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP016559.1|WP_003962201.1|1192680_1194057_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|163244
NZ_CP016559.1|WP_003962204.1|1189306_1190020_-|chlorite-dismutase-family-protein	unknown	unknown	gnl|CDD|377705
NZ_CP016559.1|WP_003962202.1|1191671_1192628_+|DUF4349-domain-containing-protein	unknown	unknown	gnl|CDD|379526
NZ_CP016559.1|WP_003955619.1|1207622_1208915_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226669
NZ_CP016559.1|WP_086012155.1|1205411_1207391_-|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl|CDD|183601
NZ_CP016559.1|WP_003962197.1|1197804_1199091_+|ribonuclease-D	unknown	unknown	gnl|CDD|223426
NZ_CP016559.1|WP_003962203.1|1190024_1191539_-|protoporphyrinogen-oxidase	unknown	unknown	gnl|CDD|237009
NZ_CP016559.1|WP_003962194.1|1202827_1203223_+|hypothetical-protein	unknown	unknown	gnl|CDD|350227
NZ_CP016559.1|WP_009997803.1|1203238_1204759_-|amino-acid-permease	unknown	unknown	gnl|CDD|129987
NZ_CP016559.1|WP_003962206.1|1184571_1185540_+|TIGR04222-domain-containing-membrane-protein	unknown	unknown	gnl|CDD|275063
NZ_CP016559.1|WP_009997805.1|1194738_1195854_-|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
NZ_CP016559.1|WP_029183089.1|1197064_1197727_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP016559.1|WP_003958301.1|1183192_1184566_+|DUF692-domain-containing-protein	unknown	unknown	gnl|CDD|235447
NZ_CP016559.1|WP_003962195.1|1200587_1202717_+|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|236864
NZ_CP016559.1|WP_003958299.1|1185608_1187141_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224154
NZ_CP016559.1|WP_003958302.1|1182194_1182965_+|peptidyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|376699
NZ_CP016559.1|WP_003958298.1|1187218_1187725_+|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NZ_CP016559.1|WP_065757083.1|1199370_1200591_+|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|273881

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003962199.1|1195945_1196647_+|DUF3000-domain-containing-protein	gnl|CDD|378665	pfam11452, DUF3000, Protein of unknown function (DUF3000). This is a bacterial family of uncharacterized proteins.	7.7922e-86
NZ_CP016559.1|WP_079133002.1|1187673_1189065_+|alpha/beta-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	1.25133e-25
NZ_CP016559.1|WP_003962201.1|1192680_1194057_+|FAD-dependent-oxidoreductase	gnl|CDD|163244	TIGR03385, Coenzyme_A_disulfide_reductase, CoA-disulfide reductase. Members of this protein family are CoA-disulfide reductase (EC 1.8.1.14), as characterized in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi, and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. [Cellular processes, Detoxification].	1.17647e-125
NZ_CP016559.1|WP_003962204.1|1189306_1190020_-|chlorite-dismutase-family-protein	gnl|CDD|377705	pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyzes the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.	5.57745e-99
NZ_CP016559.1|WP_003962202.1|1191671_1192628_+|DUF4349-domain-containing-protein	gnl|CDD|379526	pfam14257, DUF4349, Domain of unknown function (DUF4349). This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important.	1.29404e-65
NZ_CP016559.1|WP_003955619.1|1207622_1208915_-|ABC-transporter-permease	gnl|CDD|226669	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism].	6.24588e-81
NZ_CP016559.1|WP_086012155.1|1205411_1207391_-|1-deoxy-D-xylulose-5-phosphate-synthase	gnl|CDD|183601	PRK12571, PRK12571, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional.	0
NZ_CP016559.1|WP_003962197.1|1197804_1199091_+|ribonuclease-D	gnl|CDD|223426	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis].	1.12606e-84
NZ_CP016559.1|WP_003962203.1|1190024_1191539_-|protoporphyrinogen-oxidase	gnl|CDD|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	6.38822e-142
NZ_CP016559.1|WP_003962194.1|1202827_1203223_+|hypothetical-protein	gnl|CDD|350227	cd09879, PIN_VapC_AF0591-like, VapC-like PIN domain of Archaeoglobus fulgidus AF0591 protein and other similar archaeal homologs. PIN (PilT N terminus) domain of Archaeoglobus fulgidus AF0591 protein and other similar uncharacterized archaeal homologs are included in this family. This subgroup belongs to the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. PIN domains within this subgroup contain four of these highly conserved putative metal-binding, active site residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons. Matelska et al. recently classified PIN-like domains and included distant subgroups, this subgroup includes some sequences belonging to one of these, PIN_14.	3.23417e-06
NZ_CP016559.1|WP_009997803.1|1203238_1204759_-|amino-acid-permease	gnl|CDD|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.5592e-132
NZ_CP016559.1|WP_003962206.1|1184571_1185540_+|TIGR04222-domain-containing-membrane-protein	gnl|CDD|275063	TIGR04222, integral_membrane_protein, TIGR04222 domain. The majority of the proteins with a domain as described by this model have an extreme C-terminal sequence that is consists of extremely low-complexity sequence, rich in Ser or in Gly interspersed with Cys. That C-terminal region resembles ribosomal natural product precursors, although there is no evidence that C-terminal regions of these proteins undergo any modification or have any such function.	9.33078e-38
NZ_CP016559.1|WP_009997805.1|1194738_1195854_-|uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_CP016559.1|WP_029183089.1|1197064_1197727_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.05852e-23
NZ_CP016559.1|WP_003958301.1|1183192_1184566_+|DUF692-domain-containing-protein	gnl|CDD|235447	PRK05409, PRK05409, hypothetical protein; Provisional.	1.18574e-109
NZ_CP016559.1|WP_003962195.1|1200587_1202717_+|3-hydroxyacyl-CoA-dehydrogenase	gnl|CDD|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	5.11584e-110
NZ_CP016559.1|WP_003958299.1|1185608_1187141_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.80534e-64
NZ_CP016559.1|WP_003958302.1|1182194_1182965_+|peptidyl-tRNA-hydrolase	gnl|CDD|376699	pfam01981, PTH2, Peptidyl-tRNA hydrolase PTH2. Peptidyl-tRNA hydrolases are enzymes that release tRNAs from peptidyl-tRNA during translation.	3.25777e-08
NZ_CP016559.1|WP_003958298.1|1187218_1187725_+|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.00080701
NZ_CP016559.1|WP_065757083.1|1199370_1200591_+|acetyl-CoA-C-acyltransferase	gnl|CDD|273881	TIGR01930, 3-ketoacyl-CoA_thiolase, acetyl-CoA acetyltransferases. This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other].	2.44681e-158

Protein sequences

>NZ_CP016559.1|WP_003962201.1|1192680_1194057_+|FAD-dependent-oxidoreductase
MTAERLVVIGGDAAGMSAASQARRLKGPGELEIVAFERGHFSSFSACGIPYWVGGQVAERDELIARTPAEHRARDIDLRMRTEVTEIDLAGGRVRSRELESGRQEWTGYDKLVIATGARPVRPPLPGIDAPGVFGVQTLDDGQALLDALSAAPGRRAVVVGAGYIGVEMAEALLNRGFEVTVVNRGAQPMATLDPDMGALVGAAMDGLGITTVNGTEVTAVLTGADGRARAVLAGDREFPADVVVLGLGVAPGTELARAAGLPLGSSGGLLTDLSMRVRGREEIWAGGDCVEVLDLVSGRERYVPLGTHANKHGQVIGANVGGGYGTFPGVVGTAVSKVCDLEIARTGLREKDAARVGLQFVPVTVESTGRAGYYPGARPMTVKMLAERRTGRLLGVQIVGREGAAKRVDVAAVALTAGMTVEAMTALDLGYAPPFSPVWDPVLIAARKAVAAVRATG
>NZ_CP016559.1|WP_003962202.1|1191671_1192628_+|DUF4349-domain-containing-protein
MDARRGAAALTLVVAMAVTGCAGGSEKQVDGADPGVARSEGSRAAVEAQRAAPEAEGAADTEDTASEAADEAAPAQGEHIVRTAELEIRVPSVPRALKAARAAAEEAGGDVSEESTTGEEEPGGMYSSLVLRVPEDRYDAVLTRLAGAGKLLNRSARAEDVTEEVVDVRSRLATQRASVERVRKLMDRAGKLTDVVALEEQLGKRQADLEALLAKEKSLKDRTTLATITLSLQEEAEKDGTGDGDGPGFLDALGGGWDALVTSSRWTGAGIGAALPFAAVLGAAFAVWRWALRPVLRSRARRAADAVSAGERRGSAPE
>NZ_CP016559.1|WP_003962203.1|1190024_1191539_-|protoporphyrinogen-oxidase
MQSSQHAESTAADTGDPGATGRTGSGTGGAPGGAPPAHVVVVGGGISGLAAAHRLVTAGVRVTLVEASERVGGKLHTGEIAGVPVDLGAESMLARRPEGIDLARAAGLGDRLRPPATATASIWTRGALRPMPQGHVMGVPATPDSLAGLLSPEGVERIGRERDLPPAAVGDDVAVGTYVAERLGREVVDRLVEPLLGGVYAGDAYRISLAAAVPQLFAAARGHGHLLDAVDAVRRETAARQADGPVFLGIDGGVGTLPLAVAAAVRAHGGTLLTSTRALGLARVPGGWRVRTEHGVLEADGVVLAAPAWTTAELLAAESPVASAEIGRIEYASMALVTLAFRRSDTTGLPEGSGFLVPPVDGRTIKASTFSSRKWSWVDKGAPDLVLLRASIGRYGEEEQLERDDADLVRAALTDLGAATGLAARPLATEVTRWIGGLPQYPVGHRARVARVRAEVAKLPGLTVCGAAYDGVGIPACVADGRRAAEEILATPTLARGTDHGAGQ
>NZ_CP016559.1|WP_003962204.1|1189306_1190020_-|chlorite-dismutase-family-protein
MSAPEKIPNAGKKAKDLNEVIRYTLWSVFKLRDVLPEDRSGWAEEVDTLFERLAAEDVKVRGTYDLSGLRADADVMIWWHAETADELQEAYNLFRRTRLGRALEPVWSNMALHRPAEFNKSHIPAFLADETPRDYVSVYPFVRSYDWYLLPDEDRRRMLADHGKMARGYPDVRANTVASFSLGDYEWILAFEANDLYRIVDLMRHLRASEARMHVREEVPFYTGRRKSLTDLVAGLA
>NZ_CP016559.1|WP_079133002.1|1187673_1189065_+|alpha/beta-hydrolase
MEVPLDYAEPDGRRIELTVSRGRATGPTGEQQGALVFNPGGPGASGMWFPLLAGVPEWERIARAYDFVGYAPRGVDRSAPLSCQDPREAVRAPTLSPTHPSPAYKRERVAEARRYAAGCARHAGAALRHYTSLNNARDLDVLRAALGEERLTFMGASYGTYFGALYADLFPSRVRRMVLDAPVDPAREKIWYRSNLEQSLAFEGRWADFRAWVARHHDVFGLGTNPEAVGHHYEEVRARLAVRPAGGRVGPGQLQSAMLAAVYHDDFWEPRARALAAYLRGDEEPLVAQAAPRAELARGAENAAAVYTAIECNDAPWPREFAVWDRDNTALARRAPFETWDNVWMNLPCAFWPAPRQQPLEVRTRRGELPPVLILAAERDAATPYEGARELARRLKGAVLVTEEDAGTHGIGGGANDCVNGHLEEYLLRGVTPVRRASCAPHPEPDPVSLERRGAEPVLRHAV
>NZ_CP016559.1|WP_003958298.1|1187218_1187725_+|hypothetical-protein
MTDSRRRGRPRSAAPAAAGARARARAPRRTPGAYGRHRRRHRPVVLYTRYRRAKDSPNAVVCRRAKGNPMRAVAKSGLLAGLGALVAGTLAVAPRTAPPGPLSRPPPPRTSPPRRPRPAVYGSPPNGPPPRGSRSGAAPPRSPCRTRSAAAPWRFRSTTRNRTAGGSS
>NZ_CP016559.1|WP_003958299.1|1185608_1187141_+|NAD(P)/FAD-dependent-oxidoreductase
MPMRTSYDAVVVGGGHNGLVAAAYLARAGRSVLVLERSPATGGAAVSARPFAGVDARLSRYSYLVSLLPDRIVRDLGLDFAVRRRTVSSYTPVGDGGLLIGGGRTRESFAALTGGDREYTAWREFHAMTGRLAARVFPTLTEPLPRRAELRALVDDERAWRALFEEPVGVAVEEWFSHDVVRGVVLTDALIGTFADAHDPGLAQNRCFLYHVVGGGTGEWNVPVGGMGALTDALATAARRAGAEILTRHEVTHVHPEGPGAEVGYRTEDGEGTVAARHVLVNAAPRELAALLGEEPPPAAEGSQFKVNMVLRRLPRLRDGSVDPRAAFSGTFHVSEGYGQLAAAYREAAAGSLPSAPPSEIYCHTLTDPSILGPDLAAEGYQTLTLFGLHTPARLFADDPERTRDELLAATLAELDRHLAEPLADCLATDARGEPCVEARTPLDLDRELRLPGGHIFHRDLAFPYADEATGRWGVATRHPSVLLCGAGAVRGGGVSGIPGHNAAMSVLGH
>NZ_CP016559.1|WP_003962206.1|1184571_1185540_+|TIGR04222-domain-containing-membrane-protein
MGTAAVIILLAFAGACSGLLVLESRTRRGTPRFDGVAVLHDVHEAAFLSGGPPRVVDTALAAMNGDGRLLIGEPGIVSVADRVVRHPVQQAVYDTLDNAPNGSVVHLRARAMRHHTVQGIGDGLARRGLLLPRGPRRGFVDFLGCVLAVVSALATLVVIVATILSYDLDWDRPPVPFALLTLPATLTGLITGLLVVSRCRARVSKQGRQALAGYRKQHAETEDPATLVATKGPRALPKSAAQTVLVAAALTTVVLLDSTRSDGMAVAAPWCGSSDGYGDGGSGAGGGDGGGDGGGGDGGGGDGGGGDGDGGGCGGCGGCGCG
>NZ_CP016559.1|WP_003958301.1|1183192_1184566_+|DUF692-domain-containing-protein
MELGIGIGWRPEIAEVVAELPGVDWVEVVAENICPGHVPEALERLRSRGVRVVPHGVSLGLGGADRPDAGKLAALARRAEALGSPLVTEHIAFVRAGGPLTASRTLEAGHLLPVPRTRDALRVLCENVRIAQDSLPVPLAVENIAALFSWPHEELTEGQFLAELVERTGVRLLVDVANLHTNRVNRGEDPAKALDELPVEAIAYVHVAGGVERDGVWHDTHAHPVPEPVLDVLRELRARVRPPGVLLERDDDFPPGEELARELDTVRATLRSAAPRTAAVPAPRRAPTRPAEPAKNTEPAEPAEAAENTEPALPADGEAVEGAVRERLALGQVALLSALVAGTPAPEGFDARRLRTQRRALAAKRASVVAKVAPELRDILGDGYRAAFLSYARNRPMHHGYRRDALDFAEHLLIAGTPVDDRARRRLTHWWEERVTPQPPRRTTRMVRAARAVLIRR
>NZ_CP016559.1|WP_003958302.1|1182194_1182965_+|peptidyl-tRNA-hydrolase
MMARRRGAAAAGRHRPGRLARVSSEDPQHAESAESAERDEAPQYVLPLVVRIEKAGPPARTDALETAARAVLTLLADERSRDGGVWEKAVRDWEDARIRKVVRRARGAEWRKASGLPGITVTGEHAEVRVFPPVPLDGWPKELAKLQVSGTELDDPAAPPAALPDAPVLWLNPGVPMSAGKAMAQAGHAAQLAWWDLPAPARTAWAAGGFPLSVRTPSPSRWSDLTGAGLPVVRDAGFTEIAPNTCTVVADHRALL
>NZ_CP016559.1|WP_009997805.1|1194738_1195854_-|uroporphyrinogen-decarboxylase
MTAYDRTQSRTPDPSQDSAQDRSGGPRQPQTYDSAFLRACRREPVPHTPVWFMRQAGRSLPEYLKVREGIAMLDSCMRPELVKEITLQPVRRHGVDAAIYFSDIVVPLKAIGIDLDIKPGVGPVVAEPFRSRADLARLRDLTPEDVWYVTEAIGLLTAELGGTPLIGFAGAPFTLASYLVEGGPSRNHEHTKALLHSDPELWADLLDRLAEITSAFLKVQIEAGASAVQLFDSWVGALAPVDYRRSVMPASVKVFDAVAGYGVPRIHFGVGTGELLGLMGEAGADVVGVDWRVPLDEAARRVGPGKALQGNLDPAVLFAGTRAVEAMTDEVLRAAAGLEGHVFNLGHGVLPTTDPDALTRLVSYVHENTAR
>NZ_CP016559.1|WP_003962199.1|1195945_1196647_+|DUF3000-domain-containing-protein
MAAAQGHFSDHSDHSDHANGTGDRDGSGGDTTPRAFRLAVEALRGAAPRPEIGLEPARPPQRLAPYAYALEATVADDPDGEEEVLADGRLVLLYAPEGHEAWQGRFRLVTLVRAELEPEMAADPLLPEVSWSWLTGALETRGLGYGEPSGTVTRAGSHYFGGLAARRPATQIEIRASWSPEEGPDGVPDMGAHLVAWCDLLSQIAGLPPSPTGGTEAGAGVVSLPQRRGPRQR
>NZ_CP016559.1|WP_029183089.1|1197064_1197727_+|response-regulator-transcription-factor
MSVLLEQPASLVAYRPNKPTAMVVVADPRVRSTVTRHLWALGVRDVIEASSIAEARPRVGNPRDICVADVHLPDGSGLTLLSETRAAGWPNGLALSAADDIGAVRNALAGGVKGYVVTGTRTNIGHPTRPGAAPMGAGARLGHRRPPGAPSHPGGYRELSGREVEVLRLVAEGQSNKAIGVSMGLSALTVKSHLARIARKLGTGDRAGMVAVALRTGIIH
>NZ_CP016559.1|WP_003962197.1|1197804_1199091_+|ribonuclease-D
MTDAQETAAETALRTAGGAPPDDGVAAEEAPPTPLLEPREGIPAVVADADALAAVTAAFGAGSGPVAVDAERASGYRYGQRAYLVQLRRAGAGSALIDPVACPDLSPLGEALDGAEWILHAATQDLPCLRDIGMAPALLFDTELAGRLAGFPRVGLGAMVESVLGYALEKGHSAVDWSTRPLPEPWLRYAALDVELLIDLRDALEEELAEQGKLEWARQEFAAIAAAPPPAPRKDPWRRTSGMHKVRRRRQMAVVRELWTARDAVAQRRDVSPGKVLSDSAIIEAALAVPPTVQALTALPGFGHRMGRRQLEQWQSAVDRAKALSESELPQPGQPLNGPPPPRAWADKDPVAAARLSAARTAVSELAERLNLPQENLITPDTVRRVCWEPPAERSEAAVAAALAGFGARPWQIELVAPLLAQALATGA
>NZ_CP016559.1|WP_065757083.1|1199370_1200591_+|acetyl-CoA-C-acyltransferase
MPRTLRDVVFVDGVRTPFGKAGPKGIYHETRADDLVVKSIRELLRRNPGLDPARIDEVAIAATTQIGDQGLTLGRTAGILAGLPQSVPGYSIDRMCAGALTAVTTTAGSIAFGAYDVVIAGGVEHMGRHPMGEGVDPNPRFVSEKLVDESALFMGMTAENLHDRYSSITKQRADEYAVRSQEKAAKAYADGKIQQDLVPISVRRTSPEGGETGWGLATQDEPMRPGTTLENLAGLKTPFRAHGRVTAGNAAGLNDGATAAIVASEDFAREQGLPVRMRLVAYSFAGVEPEVMGYGPIPATEKALAQAGLSIEDIGLFEVNEAFAVQVLAFLEHYGIADDDPRVNQYGGAIAFGHPLASSGVRLMTQLARQFEDQPQVRYGLTTMCVGFGMGATVIWENPHFDGGTK
>NZ_CP016559.1|WP_003962195.1|1200587_1202717_+|3-hydroxyacyl-CoA-dehydrogenase
MSNTAELLKGAAELFPDEVVTQAHVRHLDLPAGAGRFALITLDNGLDHTKPTTFGPQSLAHLDAAIDQVEREAAEGSVVGVGLTGKPFIFAVGADLKGVELLRARDEALAIGRSGHEVFKRLSSLAVPTFAYYNGAAMGGGVEVGLHCSYRTVSRAIPAFSLPEVFLGLVPGWGGCALLPNLIGADRAVTVIIENSLSQNRQLKGGQVAELGIADAIFDGADFLEQSLVWTAGVLNGTVAVERAEIDRGEGWDAAVARGRAVADGKVHGAAPAAYRALDIIAAAKDGDLQAGFDAEDEALADLIMGGELRSGIYAFNLVQKRGKRPAGAPDKSLARPVTKVGVVGAGLMASQLALLFVRRLEVPVVLTDIDQERIDKGVGYVHSEIDKLLGKGRIDQDRANRLKGLVTGVLDKAEGFADADFVIEAVFEEMGVKRQVFAEVEAVAPAHAILATNTSSLSVSEMAAELKHPERVVGFHFFNPVAVLPLLEIVRGEQTDDASLATAFAVAKKLRKTAVLVKDAPAFVVNRILTRFMGEIQNVIDEGTSVEVAERAVAPLGLPMSPLVLLELVGPAIGLHVSETLNRAFPDRFTVSPNLQAVVAAGKRGFYRYDSGRPELDPEVAALLRQGDTVLTGEQVRARVLDAVAQEIGLMLDEGVVAEAQDIDLCLITGAGWPFHLGGITPYLDREGVSQRVNGKPFLAPGTASVPA
>NZ_CP016559.1|WP_003962194.1|1202827_1203223_+|hypothetical-protein
MTEETGPVAPTLLIVDGANVVGSVPDGWWRDRRGAALRLRDRLAQYAEPGVEGVPGPLEIVLVVEGAARGTGSVPGVRVADAPGSGDDLIAELARAAAHRPCVVVTADRELRRRVLAEGARVAGPRTVHRP
>NZ_CP016559.1|WP_009997803.1|1203238_1204759_-|amino-acid-permease
MTTDTDPEGRTGIFRTKSVEQSIRDTEEPEHGLKRSLSALDLTVFGVGVIIGTGIFVLTGAVAKETAGPATALAFVVAAIVCGLAALCYAEFASTVPVAGSAYTFAYASLGELPAWIIGWDLVLEFAVGTAVVAVGWSGYLRSLMDNVGWHLPQALSGTTPEHGFAFDLLAFLLVLLLTAILVLGMKLSARVTTAVVAIKVAVVLIVIVAGSFFIKASNYDPFIPPAVREPGESGLQQPLVQLMFGYAPTSFGVMGIFTAASIVFFAFIGFDVVATAAEETRNPQRDMPRGILGSLFICTVLYVAVSIVVTGMQHYTRLTVDAPLADAFKSIGHPWYAGVISFGAVIGLTSVCLILLLGQTRVFFAMSRDGLLPRFFSVTHPRYRTPYRATVLLGVVIAIVAGCTNIEELAALVNIGTLFAFVVVALGVIILRRTRPDLPRAFRTPFVPWLPALSVAASLWLMLNLPSETWLRFGLWMLLGVVVYWLYGRRHSRLEPGAPVPHRSH
>NZ_CP016559.1|WP_086012155.1|1205411_1207391_-|1-deoxy-D-xylulose-5-phosphate-synthase
MKDSREARRSRVVVGDAEGLLAGVTGPRDLDRLTPEQLDELAAEIRAFLVDAVSKTGGHLGPNLGVVELTIALHRVFDSPRDRVLWDTGHQSYVHKLLTGRQDFARLKMKGGLSGYPARAESDHDIIENSHASTVLGWADGLAKANELLGKDDHVVAVIGDGALTGGMAWEALNNIAAAKDRPLVIVVNDNERSYAPTIGGLANHLATLRTTDGYERFLARGKDLLGRTPVVGKPLYETLHGAKKGLKDVIAPQGMFEDLGLKYLGPIDGHDMEALESALSRAKRFGGPVIVHCLTEKGRGYQPALQDEADRFHAVGKIHPDTGLPIASSGLDWTSVFGEEMVRLGEERPDIVAITAAMLHPVGLDRFAKAFPHRVYDVGIAEQHGAVSAAGLATGGLHPVFAVYATFLNRAFDQVLMDVALHKCGVTFVLDRAGVTGTDGASHNGMWDLSILQVVPGLRISAPRDADQVRAQLREAVAVEDAPTVVRFSKGAVGPAVQAVGRVGGMDVLREAGAERPDVLLVSVGALAPMCLEIADLLDKQGISTTVVDPRWVKPVDEALAPLAERHRVVVTVEDNIRVGGVGSAVAQALRDAGVDVPLRDFGIPPRFLDHASRAEVLTEIGLTAPDIARQVTGLVARLDGRYDTTAGAAEAAEPVRD
>NZ_CP016559.1|WP_003955619.1|1207622_1208915_-|ABC-transporter-permease
MTDRADLAKDRGQGQDTPPEPPPAVPAVDPRLLVREQGLAGYLTAFRRTVSAGELGSLPVVLGLVAIAAVFQSLNENFLSAQNLSNIAVAMVGTGMMSVGIIFVLLLGEIDLSVGAVSGVSGAIVAVLSVTHGVNEWLAVLAAVAGGAAIGALHGFFFAVIGAPAFAVTLAGLLFWQGFMLQLLGSSGTLNLDPDGVVGQLNTYYFSDVAAAYGLAALAVAVFFLTALADLRRRAAAGVPSRPFTDIALRTAGLAAVAFAAAYVLNQYKGLPLALVLFLAALVTTDFVLRRTAYGRTVLALGGSVEAARRAGIPVHLVRISVFAVAGTFAAIGGLFMASKIAAANQSAGGGELLMNVIAAAVIGGTSLFGGRGRTWNALLGVMVIVSIQYGLALEGIKSPVQFMITGGVLLATVVIDSVTRRTQRTAGRA

Crispr_ID: NZ_CP016559_3

• CRISPR_ID: NZ_CP016559_3
• CRISPR_location: 1234099-1234446
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NZ_CP016559_3

Consensus_repeat	Method
CTCCGGCNCGGGCTCCGG	CRT

spacers of NZ_CP016559_3

>3.1|1234117|42|NZ_CP016559|CRT
CCGGCGCTCCGGCCGGCACTCCCGCTCCGGCTCTGCCCGACG
>3.2|1234177|30|NZ_CP016559|CRT
CCGTTGATCCGGCCGACGTTCCCGCTCCGG
>3.3|1234225|24|NZ_CP016559|CRT
CCGTTGATCCGGCTGACGCTCCGG
>3.4|1234267|30|NZ_CP016559|CRT
CCGCGACTCCGACTCCTGTTGCGGCTCGGG
>3.5|1234315|18|NZ_CP016559|CRT
CTCCGGCGCCAGCCGACG
>3.6|1234351|18|NZ_CP016559|CRT
CCGTTGATCCGGCTGACG
>3.7|1234387|42|NZ_CP016559|CRT
TGCGGACCGAGGCCGTGGCTCCCGTTCCGATCCCGGTCGGTA

CRISPR arrays and Neighbor proteins around NZ_CP016559_3

CRISPR arrays

The CRISPR arrays of NZ_CP016559_3

>merge|NZ_CP016559|3|1234099-1234446|CRT
CTGCGGCTCGGGCTCGGGCCGGCGCTCCGGCCGGCACTCCCGCTCCGGCTCTGCCCGACGCTCCGGCTCGGGCTCGGGCCGTTGATCCGGCCGACGTTCCCGCTCCGGCTCCGGCCCGGGCTCCGGCCGTTGATCCGGCTGACGCTCCGGCTCCGGCCCGGGCTCCGGCCGCGACTCCGACTCCTGTTGCGGCTCGGGCTCCGGCCGGCGTTCCCGCTCCGGCGCCAGCCGACGCTCCGGCCCGGGCTCCGGCCGTTGATCCGGCTGACGCTCCGGCTCCGGCTCCGCTGCGGACCGAGGCCGTGGCTCCCGTTCCGATCCCGGTCGGTACTCGCGCTCCGGTCCCGG

>NZ_CP016559|3|1|1234099-1234446|CRT
CTGCGGCTCGGGCTCGGG	CCGGCGCTCCGGCCGGCACTCCCGCTCCGGCTCTGCCCGACG
CTCCGGCTCGGGCTCGGG	CCGTTGATCCGGCCGACGTTCCCGCTCCGG
CTCCGGCCCGGGCTCCGG	CCGTTGATCCGGCTGACGCTCCGG
CTCCGGCCCGGGCTCCGG	CCGCGACTCCGACTCCTGTTGCGGCTCGGG
CTCCGGCCGGCGTTCCCG	CTCCGGCGCCAGCCGACG
CTCCGGCCCGGGCTCCGG	CCGTTGATCCGGCTGACG
CTCCGGCTCCGGCTCCGC	TGCGGACCGAGGCCGTGGCTCCCGTTCCGATCCCGGTCGGTA
CTCGCGCTCCGGTCCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_029183088.1|1216558_1220398_+|alpha-mannosidase	unknown	unknown	gnl|CDD|377950
NZ_CP016559.1|WP_106428645.1|1228774_1229920_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP016559.1|WP_009997800.1|1224152_1224632_+|sulfurtransferase	unknown	unknown	gnl|CDD|238779
NZ_CP016559.1|WP_003955604.1|1226653_1226956_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003955603.1|1227231_1228761_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|238796
NZ_CP016559.1|WP_003962181.1|1241990_1243040_-|ornithine-carbamoyltransferase	unknown	unknown	gnl|CDD|179366
NZ_CP016559.1|WP_003962179.1|1244701_1247284_-|polynucleotide-kinase-phosphatase	unknown	unknown	gnl|CDD|274963
NZ_CP016559.1|WP_003955590.1|1247280_1248846_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1	unknown	unknown	gnl|CDD|274962
NZ_CP016559.1|WP_003955598.1|1234475_1235648_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NZ_CP016559.1|WP_003955595.1|1238721_1241025_-|bifunctional-salicylyl-CoA-5-hydroxylase/oxidoreductase	unknown	unknown	gnl|CDD|236203
NZ_CP016559.1|WP_003962183.1|1237533_1238397_+|PaaX-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225864
NZ_CP016559.1|WP_003955589.1|1248966_1249251_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_065757084.1|1243258_1244491_-|arginine-deiminase	unknown	unknown	gnl|CDD|234949
NZ_CP016559.1|WP_003955609.1|1220556_1223283_-|aconitate-hydratase-AcnA	unknown	unknown	gnl|CDD|236445
NZ_CP016559.1|WP_003955600.1|1232287_1233475_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP016559.1|WP_003955597.1|1235802_1237410_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341268
NZ_CP016559.1|WP_003955608.1|1223491_1223938_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_CP016559.1|WP_003962182.1|1241021_1241849_-|enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|181329
NZ_CP016559.1|WP_003955601.1|1230408_1231950_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP016559.1|WP_009997798.1|1224654_1226394_-|phosphotransferase	unknown	unknown	gnl|CDD|270916

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_029183088.1|1216558_1220398_+|alpha-mannosidase	gnl|CDD|377950	pfam07971, Glyco_hydro_92, Glycosyl hydrolase family 92. Members of this family are alpha-1,2-mannosidases, enzymes which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by hydrolysis. They are critical for the maturation of N-linked oligosaccharides and ER-associated degradation.	0
NZ_CP016559.1|WP_106428645.1|1228774_1229920_-|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	6.93378e-41
NZ_CP016559.1|WP_009997800.1|1224152_1224632_+|sulfurtransferase	gnl|CDD|238779	cd01521, RHOD_PspE2, Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins.	4.08268e-53
NZ_CP016559.1|WP_009997798.1|1224654_1226394_-|phosphotransferase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.23438e-40
NZ_CP016559.1|WP_003962181.1|1241990_1243040_-|ornithine-carbamoyltransferase	gnl|CDD|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	0
NZ_CP016559.1|WP_003962179.1|1244701_1247284_-|polynucleotide-kinase-phosphatase	gnl|CDD|274963	TIGR04075, Ser/Thr_phosphatase_family_protein, polynucleotide kinase-phosphatase. Members of this protein family are the bacterial polynucleotide kinase-phosphatase (Pnkp) whose genes occur paired with genes for the 3' terminal RNA ribose 2'-O-methyltransferase Hen1. All members of the seed alignment belong to a cassette with the Hen1. The pair acts in bacterial RNA repair. This enzyme performs end-healing reactions on broken RNA, preparing from the RNA ligase to close the break. The working hypothesis is that the combination of Pnkp (RNA repair) and Hen1 (RNA modification) serves to first repair RNA damage from ribotoxins and then perform a modification that prevents the damage from recurring. [Transcription, RNA processing].	0
NZ_CP016559.1|WP_003955590.1|1247280_1248846_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1	gnl|CDD|274962	TIGR04074, Methyltransferase_type_12, 3' terminal RNA ribose 2'-O-methyltransferase Hen1. Members of this protein family are bacterial Hen1, a 3' terminal RNA ribose 2'-O-methyltransferase that acts in bacterial RNA repair. All members of the seed alignment belong to a cassette with the RNA repair enzyme polynucleotide kinase-phosphatase (Pnkp). Chemically similar Hen1 in eukaryotes acts instead on small regulatory RNAs. [Transcription, RNA processing, Protein synthesis, tRNA and rRNA base modification].	0
NZ_CP016559.1|WP_003955603.1|1227231_1228761_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|238796	cd01555, UdpNAET, UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.	4.19577e-128
NZ_CP016559.1|WP_003955595.1|1238721_1241025_-|bifunctional-salicylyl-CoA-5-hydroxylase/oxidoreductase	gnl|CDD|236203	PRK08255, PRK08255, bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase.	0
NZ_CP016559.1|WP_003962183.1|1237533_1238397_+|PaaX-family-transcriptional-regulator	gnl|CDD|225864	COG3327, PaaX, Phenylacetic acid-responsive transcriptional repressor [Transcription].	1.0641e-34
NZ_CP016559.1|WP_065757084.1|1243258_1244491_-|arginine-deiminase	gnl|CDD|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_CP016559.1|WP_003955609.1|1220556_1223283_-|aconitate-hydratase-AcnA	gnl|CDD|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
NZ_CP016559.1|WP_003955600.1|1232287_1233475_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	4.49504e-64
NZ_CP016559.1|WP_003955597.1|1235802_1237410_+|AMP-binding-protein	gnl|CDD|341268	cd05958, ABCL, 2-aminobenzoate-CoA ligase (ABCL). ABCL catalyzes the initial step in the 2-aminobenzoate aerobic degradation pathway by activating 2-aminobenzoate to 2-aminobenzoyl-CoA. The reaction is carried out via a two-step process; the first step is ATP-dependent and forms a 2-aminobenzoyl-AMP intermediate, and the second step forms the 2-aminobenzoyl-CoA ester and releases the AMP. 2-Aminobenzoyl-CoA is further converted to 2-amino-5-oxo-cyclohex-1-ene-1-carbonyl-CoA catalyzed by 2-aminobenzoyl-CoA monooxygenase/reductase. ABCL has been purified from cells aerobically grown with 2-aminobenzoate as sole carbon, energy, and nitrogen source, and has been characterized as a monomer.	0
NZ_CP016559.1|WP_003955608.1|1223491_1223938_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.92747e-40
NZ_CP016559.1|WP_003962182.1|1241021_1241849_-|enoyl-CoA-hydratase-family-protein	gnl|CDD|181329	PRK08258, PRK08258, enoyl-CoA hydratase family protein.	2.65952e-137
NZ_CP016559.1|WP_003955601.1|1230408_1231950_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.54435e-59
NZ_CP016559.1|WP_003955598.1|1234475_1235648_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	7.07985e-93

Protein sequences

>NZ_CP016559.1|WP_003955600.1|1232287_1233475_+|serine-hydrolase
MRVRTGMVGFTAAAVAFTVLTGPAQALDQGPGQGQGRAQGQAQEQGSGKRSHTQQALDELVRAGAVGVVARSEKQGAVWKGTAGVADRTTGKPRKANEHFRIGSITKTFVATVLLQLEAEGRLSLDDTVERHLPGLIRDGGNDGRKITVRQLLNHSSGLPEYLRNQTFYDRYINLPGFLENRYTQHSPADLVRTGMALGQDFAPGTRFSYSNTGYIVAGMIVEKVTGNRYEDEIRERIAEPLKLRGTGSPGTATGIPRPSARGYGVGPDGTLHDLTELSPTVAWSAGDMISTTADLNRFFGALLGGKVLPKKQLNAMKTTLPDPNGFIEGYGLGLYTTTTKCGTKLWGHAGGIMGWGADAVTTEDGRHTLAASANGGADGFEPVVDAEYCGTKKR
>NZ_CP016559.1|WP_003955601.1|1230408_1231950_-|MFS-transporter
MSTPHPRAAYTASAATPAHRGGKGIALLVIASAQLMVVLDITIVNIALPHIQTALSFSTENLSWVVSAYTLAFGGLLLLGGRAGDILGRRRVFLAGVGLFALASLLGGLSQNGGQLLAARALQGAGAAVASPTALALISTIFREGPERNRAFGAFAAVSGGGGAIGLLAGGMLVQWLDWRWVFFVNVPIAVLIVVATPRYIRETARHPGHFDLIGAVTATLGMVALVYGFIRAAHDGWRDPVTLGSFAAAAVLLTVFVLVERHSRQPITPLRMFADRNRVGAYGIMLNLAAAIFGMFFFLTLFVQDVLHFSPLRAGLAFLPVSVIIVLGAQVTSRLVPRFGPKPFMVSGALCAAAGLAWLTRIDARSTYTGSVLGPMLVFSLGMGMQFISITLTALSGVRGEESGAASGLLNTAQQVGGSLGLAILVTVFSTASAGEAHRQLLGFLVRATPEQKLAFRRTGMMPPPWGDRVLTAGISAAFVAAAVFAAVAAVIALLVIRVRPADLERFRGGHR
>NZ_CP016559.1|WP_106428645.1|1228774_1229920_-|serine/threonine-protein-phosphatase
MDEGHHSRIAETADRIGTTLDERTTCEELVGFLAVAGPDGHAPAAVAVDLITDDPREPGAPRVRRAAVTGDGELLPARPPAEVLRGEAGADGPRLALPLIHRGQVLGAVLVVHTQGAFTAHELLLARSAARRAAVAIDHSRLFGRSQRTAGELQRALLTDPGQPHPNLRVATRYLPSGAGTLVGGDWFEAVRLHFGRTLLVMGDVMGHGVEAAVDMNSYRRALRDAAAADLPPHRILRRLDQEIAGHAARRPAACLLAQMDPVRGLVSLSSAGHLPPVTLSASGTVELVDVPVGPPLGTGVGGYDRAQRPLGPDDTLLMFTDGLVERRGEDIDVSLARLARLRPDPRAPLDTLVDEILARLDAAHAEDDVAVLAARISFPV
>NZ_CP016559.1|WP_003955603.1|1227231_1228761_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MADDYLVRIGKLIRDARQHRGWTQTQLAEALGTSQSAVNRIERGNQNISLEMIARIGEALDSEIVSLGYAGPMHLRVVGGRRLSGAIDVKTSKNACVALLCGSLLNKGRTVLRRVARIEEVFRLLEVLNSIGVRTRWINEGVDLEIVPPARLDMDAIDADAARRTRSIIMFLGPLLHRMDSFKLPYAGGCDLGTRTIEPHMIALRRFGLDITATEGLYHARVERSTAPGRPIVLTERGDTVTENALLAAARHDGVTVIRNASSNYMVQDLCFFLEALGVRVEGVGTTTLTVHGVPDIDVDVDYSPSEDPVEAMSLLAAAVVTESELTIRRVPIEFLEIELAVLEEMGLDHDRSSEYTADNGRTRLVDLTVRPSKLEAPIDKIHPMPFPGLNIDNVPFFAAIAAVAQGQTLIHDWVYDNRAIYLTDLNRLGGRLQLLDPHRVLVEGPTRWRAAEMMCPPALRPAVVVLLAMMAAEGTSVLRNVYVINRGYEELAERLNSVGAQIEIFRDI
>NZ_CP016559.1|WP_003955604.1|1226653_1226956_+|hypothetical-protein
MTPHKKRRVHVKRRMRSAGVTVAMLGAALVMSSGVAQAQEQQPAPRPSIGLINITGPLIYNTGDIDLLEDVFEHISIPILGQAVHQMYDWAKFDGKLFRR
>NZ_CP016559.1|WP_009997798.1|1224654_1226394_-|phosphotransferase
MNSAAHRIGPDSAPDRYRLLRSIGRGGEAVLYLAEIELAGAVEPVVVKVLDSRTALTAEEFDRLSRSWSEQAELLRFVHRPGVVGVREHFQGPPIHPPGGSGDLPGRALALVMNRVDGLDLADWRAGRTLADPAGRRELLRTLEQLADVLDWLHSGRATPSGRAVVHGDLSPGNVMVDEDGQATLVDFGLSKLTADHRTAEIWFTPGYAAPEVFEGLRTPATDRYAFGAIAYFLLTGGAPPPSPGQLAGGLAALPRIAGLAPARRERVVAIASADPDRRPASLSAWVADLRHGVTPGPAAPHPPTVQDAPPPPLPPPPAPPRPVAAPPPVVPPSPPPPPEPRPAAKIPPRRPPLPRPAPPPPRRRRRGPVLAAAAGLVLLTVLAAVGVRSLLGGGDGGGDDRAAAPSSPSLSATLEAQLPSPRESVPVPDPAVPPEQRAADPRPEPDSAPLTTFRVLDSGGGSLRAGIGALDAKRYETALVSGPHYCSGFAEYNLNKEWAGLTLTAGIDDESPDRAARLVITLDEDNVLHTGELRLGHPEPLVLDVRGGLRLRIDYAETRQGYCYRGDVVLGDPTLTRR
>NZ_CP016559.1|WP_009997800.1|1224152_1224632_+|sulfurtransferase
MTTTAPNPVLRGGLATPAEAAAHFRASLRFHADVSDVATALAAGDGGGAGFVLLDSRSPDSWEQGHIPGAVHLPTALIPERAGELLDPSVPVVTYCWGPGCNGATRAALALAGLGYRVKEMLGGFEYWVREGFGYETGQGPARRAADPLTAPVAGVCGC
>NZ_CP016559.1|WP_003955608.1|1223491_1223938_-|Lrp/AsnC-family-transcriptional-regulator
MTTISLDAIDWRILDVLQADGRASFADLARAVAMSASAVTERVRRLEEAGVISGYAAVVDPDKVGLTILAFVRLRYPNGNYRPFHDLVAAMPEILEAHHVTGDDCFVIKVAARSMRHLEEVSGRIGALGSVTTSVVYSSPLPRRAVGR
>NZ_CP016559.1|WP_003955609.1|1220556_1223283_-|aconitate-hydratase-AcnA
MSANSFDARSTLRVGDESYEIFKLDKVEGSARLPYSLKVLLENLLRTEDGANITADHIRALGGWDSQAQPSQEIQFTPARVIMQDFTGVPCVVDLATMREAVKELGGDPAKINPLAPAELVIDHSVIADKFGTKDAFGQNVELEYGRNKERYQFLRWGQTAFDEFKVVPPGTGIVHQVNIEHLARTVMVRNGQAYPDTLVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGELTPGTTATDLVLTITEMLRKHGVVGKFVEFYGEGVAATSLANRATIGNMSPEFGSTAAIFPIDGETLNYLRLTGRSQQQVALVEAYAKEQGLWLDPTAEPDFSEKLELDLSTVVPSIAGPKRPQDRIVLANAAEQFALDVRNYVADDEEAGKESFPASDAPASSDGVPTKPTLVTAPDGSTYEIDHGAVTVAAITSCTNTSNPYVMVAAALVAKKAVEKGLTRKPWVKTTLAPGSKVVTDYFDKAGLTPYLDKVGFNLVGYGCTTCIGNSGPLPEEVSKAVNEADLAVTSVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGSMKVDITREALGIDTEGNPVYLKDIWPTEAEVNDVVANAIGEDMFAKSYQDVFAGDAQWQALPIPTGNTFEWDTESTYVRKPPYFEGMEMEPAPVQDIAGARVLAKLGDSVTTDHISPAGAIKADTPAGQYLTEHGVERRDFNSYGSRRGNHEVMIRGTFANIRLRNQIAPGTEGGFTRDFTQAATADAAPVSFIYDASRNYIEQGIPLVILAGKEYGSGSSRDWAAKGTALLGVKAVIAESYERIHRSNLIGMGVLPLQFPEGASAQSLGLTGEETFSFTGVTELNEGTTPRTVKVTTDTGVEFDAVVRIDTPGEADYYRNGGIMQYVLRNLIRG
>NZ_CP016559.1|WP_029183088.1|1216558_1220398_+|alpha-mannosidase
MPGRTGSAARTAAALAAVLLTVTAPSAAVALPESPAELPSRAGEFNTSFETTERQPDWRNSVDLASDGQKRSSGVHGGFSTGIPGNVTDRVKEVRASGEHEGAGETKENLVDLEPTTKWLEFAATSWIEFDTDAPVRVSAYALTSANDEEKRDPRDWTLKGSADGREWTVLDTRAEERFEQRHQTRTFTVGEPGQVPAYAHYRLEITRNNGAPLTQLADVQFSNGDTSAPVPDDMRSLVDRGPTGSPTAKPKAGFTGLRALRYAGTHRAEGRGYSYNRVFDVDLPVGRDTELSYRVYPAMAEGVRDYAATQVAVDLAFTDGTLLSELAARDSHGGRLSPQGQGEAKRLYVNQWNQVRSLVGEVAAGRTVDRILVAYDSARGPARFQGWIDDITLRPKPPERRPERLSDYASTTRGTNSAFWFSRGNTFPATAVPHGFNFWTPVTRADSTDWLYEYQRGNNAANLPTVKAFSASHEPSPWMGDRQTFQLMPSAAPGTPETDRERRALAFRHENETARPHYYDVTFENGLRAELAPTDHAATMRFTYPGDDASVVFDNVTQQGGLTLDAASASFSGFSDVRSGLSTGATRLFVHGVFDAPVTGSASEGVRGHFRFDAGADRTVVLRIATSLISVDQARKNLADEIPPGTPFEEVKERAQDAWDALLGRVEVEGATEDQRVTLYSSLYRLYLYPNSGFENTGTKERPRYRYASPFSPMTGPDTPTHTGAKIVDGTVYVNNGFWDTYRTTWPAYSFLTPRKAGELIEGFVQQYRDGGWISRWSSPGYADLMTGTSSDVAFADAYVKGVRGFDAKAAYEAALKNATVVPPAPGVGRKGMTTSPFTGYASTATHEGLSWSLEGHLNDYGISRMARALYERTGEKRYREEAEYFAERARNYVTLFDRQAGFFQGRDPKGQWRVPSASYDPRIWGYDYTETNGWGYAFTAPQDSRGLANLYGGRAELGRKLDTYFATPETASPEFKGSYSGVIHEMTEARDVRMGMYGHSNQVAHHVTYMYNAASQPWKTQEKVREVLSRLYTGSEIGQGYHGDEDNGEQSAWYLFSALGFYPLVMGSGEYAIGSPLFRKVTVKLDGGRELVVKAPRNSARNIYVQGLKVNGKPWHSTALPHGVVARGGTLEFAMGPEPSAWGTGKGAAPVSLTRDDRVPEPRRDAVTGAGELFDDSSATSGELTAGAVELPVPAGTRAVQYTLTSADRASAPTGWVLQGSQDGTVWRDLDRRSQERFTWDRQTRVFSVPRPGTYPRYRLVPEGGGGARLAEIELLA
>NZ_CP016559.1|WP_003955598.1|1234475_1235648_-|acyl-CoA-dehydrogenase
MTVFSLDPDRIVWCAALRALAADTLRPLAERGAPGRVNRPLLAALGEHGLLRRMFASGALDLCLLRESLAERCTEAETALALQGLGTFPVLQAGTSEQRERWLPGVTDGTAVAAFALSEPDAGSDAAALALRAEPDPSGGWRLYGGKRWISNAPEADFYTVFARTTEGAGARGVTAFLVPGDRPGLTGVPLDMLAPHAIGALTFDGTPVGGADVLGAVDGGFAVAMRTLDLFRPSVGAFAVGMAQTALDATLEHTARRRAFGGPLAELQAVAHRVAEMATRTEAARLLVYAAAAAYDAGAAEVPRRSAMAKLYATEAAQYVVDSAVQLHGACALQRGHPLERLYREVRAPRIYEGASEVQRSIIARALYRERPSGAGARGETADPQGRAG
>NZ_CP016559.1|WP_003955597.1|1235802_1237410_+|AMP-binding-protein
MELTPSAHLDTFTRDHLPPPDQWPLITPLPGPDRINCGVELLDGTIARLGGDRPALRAADGTVWSYDELRERVDRTAHVLSGPLGVTPGERVLLRGPTSPGLAACWLAVMKAGAVAVTVLDRHRPPELAAICEIAAVRHALCDARSLADLEAAGVPGLRITPYGGDTPRDLLRLTRGRPTVYPAVDTAADDVALIAFTSGTTGRPKGCLHFHRDVLAVADTFAAQVLRPEPDDLFAGSAPLGFTFGLGGLVVFPLRVGAAALLLERAGPRQLLPAIAAHRVSVLLTAPTAYRVMLSGPDDGGLGPLRRCVSAGENLPADTWHGWRERTGIRIINGIGATELLHIFISAADDAIRPGTTGVPVPGWQARIVDGQGRPLPDGMPGLLAVRGPVGCRYLDDPRQREYVRDGWNITGDTYVRESDGYFRYVARADDMIVSAGYNIAGPEVEEALLCDPDVVEAAVVGRPDPLRGQIVVAHVVLREGVPAGEATAEALMVAVRRRLSPYKCPREIVFTRELPRTPTGKLQRFRLRTGRPA
>NZ_CP016559.1|WP_003962183.1|1237533_1238397_+|PaaX-family-transcriptional-regulator
MAEQHTPRSLIVTLYGAYGREAPEPLPVAELIRLLGAVGVDPPSVRSAVSRLKRRGLLLPGRTADGAAGYALSADARQLLDDGDLRIYGRRPPLLSDGWVLAVFSVPESERSKRHLLRSRLGRLGFGTAAPGVWIAPARLYEETRHTLRRLRLDPYVELFRGEHLGFAATAEAVARWWDLGAIAKRHEEFLGEQEPVLRAWWDGREPSPEGAYRDYLPALDSWRRLPYLDPGLPLELLPPQWPGERSAQVFGELHALLRDVGARFVHGPEAAPLPDGPPGAAPVGPG
>NZ_CP016559.1|WP_003955595.1|1238721_1241025_-|bifunctional-salicylyl-CoA-5-hydroxylase/oxidoreductase
MTPAPAPPPLRVAVIGGGPGGLYAAVLLKRLDPRREITVWERNAPDDTFGFGVVLSDETLGGIASADPAVHRALRREFVRWDDITVTHRGHRLTSGGHGFAALGRRRLLEILHHRCATLGIRLRFRTPAPPAADLARTHDLVVAADGVHSTTRETHAGVFRPRLATHRCRYVWLAADLALDAFRFDIAETPHGVMQLHGYPYAPGASTVIIEMREEVWRAAGLDAPGPGGLARSLEHCAAVFADTLDGRPLRSHRSSWTAFRTVVNEHWSSGRTVLLGDAAHTAHFSIGSGTKLAVEDALALAACLRERPTVAEALAAYEAERRPVVESTQRAATASLRWFEELADRLEQPPRQFAFNLLTRSRRVTHGNLRLRDPAFTDAVERDFGCPPGTPPMFTPFRLGPLELRNRIVVSPMDMYSAVDGVPGEFHLVHLGARALGGAGLVMTEMVCVSAEGRITPGCTGLWTGEQAAAWRRITRFVHDQAPGTAIGVQLGHAGRKGSTRLMWEGMDDPLPERNWPLSAASPLPYRPGVSQVPHALDRAGLTAVREEFAAAARRAADSGFDLLELHCAHGYLLSGFLSPLTNRRTDAYGGPLEHRLRYPLEVFDAVRAVWPDDRPMTVRISATDWADGGTTAEDSVAIARAFAAHGAAAIDVSTGQVVPGERPEFGRSYQTPYADRIRGALGVPVIAVGAISSWDDVNSLLLAGRADLCALGRPHLHDPHWTLRAAAEQGYTGPGAPWPPPYRAGSRRPPTGRTDAPKPRLTLE
>NZ_CP016559.1|WP_003962182.1|1241021_1241849_-|enoyl-CoA-hydratase-family-protein
MSPFPSSATRTERWRHLRLDQCDGVATVTLACPERLNALTFGAYADLRDLLAELARERAVRALVLGGEGRGFCSGGDVDDIIGATLTMDTAQLLDFNRMTGQVVRAIRESPFPVIAAVHGVAAGAGAVLALAADFRIADPSARFVFLFTKVGLSGGDMGAAYLLPRVVGLGHATRLLMLGEAVRAPEAERIGLLSEVTEEGRAPARAAELARTLAEGPALAHAQTKALLTAELDMPLAASVELDAATQALLMTSEDYAEFHAAFTAKRPPRWRGR
>NZ_CP016559.1|WP_003962181.1|1241990_1243040_-|ornithine-carbamoyltransferase
MAIDLEGRHFLKELDFTPEEFRALIVLAARLKAEKRAGTERRRLTGKNIALIFEKASTRTRCAFEVAAADQGAFTTYIDPAGSHIGRKESAKDTARVLGRMFDAIQFRGDAQATVEQLAEYAGVPVYNGLTDEWHPTQMLADVLTMTEHCDKPLEEMALAYLGDARFNMGNSYLITGALLGLDIRIVAPRAYWPAEEFIGRARELARSTGARITLTEEVPEGVRGADFVATDVWVSMGEPQEVWDERIKALSPYTVTMDVLRATGNPQVRFLHCLPAFHDLDTSVARGIHGRYGLTELEVTDEVFESEHSVVFDEAENRMHTIKAVMVATLARDPAPEPVAPALAPAAG
>NZ_CP016559.1|WP_065757084.1|1243258_1244491_-|arginine-deiminase
MGFHVDSETGRLRRVILHRPDLELKRLTPSNKDTLLFDDMLWVRRARQEHDGFADVLRDRGVQVHLFGDLLREALEVPEARKLVLDRVFDEKEYGPLATDHLRAAFDELPTSALVGALVGGMTKREFLAGHPEPASVRFHVMDLDDFLLDPLPNHLFTRDTSAWIYDGVSINAMRWPARQRETVHFEAIYKHHPLFTGPLAGDFHHWSEGQDDYPSTIEGGDVLVIGRGAVLIGMSERTTPQAVEMLARGMFAAGSARTIVALDMPKRRAFMHLDTVMTMVDADTFTQYAGLGMLRSYTIEPADGGLGLRVTDHPPEQMHTAIAAALGMQDIRVLTATQDVHSAEREQWDDGCNVLAVEPGVVVAYERNVTTNTYLRKRGIEVIEIPGSELGRGRGGPRCMSCPVERDAA
>NZ_CP016559.1|WP_003962179.1|1244701_1247284_-|polynucleotide-kinase-phosphatase
MTTTDPTGSATTVPKRLLPVTDLSLVVLIGASGSGKSTFARRHFKPTEVISSDFCRGLVADDENDQSASRDAFDVLHYIAGKRLAAGRLTVVDATHVQAESRRQLIRLAREHDVLPIAVVLDLPEDVCVERNARRPDRAGMPARVVQRHRRELRRSLRGLEREGFRKVHVLRGQEEVDAAEVVLERRFNDLRHLSGPFDIVGDIHGCSSELETLLDRLGYRDGVHPGGRTAVFVGDLVDRGPDSPGVLRRVMSMVASGNALCVPGNHENKLGRYLKGRKVQHTHGLAETVEQLEKEDGTFRQQVLEFIDGLVSHYVLDGGDLVVCHAGLPEKYHGRTSGRVRSHALYGDTTGETDEFGLPVRYPWAEEYRGRAAVVYGHTPVPRTSWINNTICLDTGVVFGGRMTALRWPERELVDVPAEKIWYEPVRPLVADAPGSREGRPLDLADVHGRRIVETRELARISVREENAAAALEVMSRFAVDPRLLPYLPPTMAPTATSRQDGFLEHPAEAFAQYRADGVERVVCEEKHMGSRAVVLVCRDAATARERFGVDGPTGALYTRTGRPFFDDETVTEEILDRLRRAVTGAGLWEELAAPGADGEGWLLLDAELMPWSLKARGLLRNQYAAVGAASGAVFPGALAALESAAARGSDVDGLLRAQRERAADAAAFTEAYRRYCWTTEGLDGVRLAPFQILAAPGRSLAGVPHDQQLAWLDRLVEHDPTGLLRTTGRLVVDTTDEASVAAGTDWWLELTGRGGEGMVVKPLQPLTRDGKDRPVQPGVKVRGREYLRIVYGPEYTRPENLERLRDRFLGHKRSLALREYALGLEALERLAAGEPLWRIHEAVFAVLALESEPVDPRL
>NZ_CP016559.1|WP_003955590.1|1247280_1248846_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1
MFLTISTTGTPEAPATDLGHLLHKHPDNPQRRSTAHGIAHVFYPEATPERCTAALLLEVDPVALVRRGKGKGRGGAPDAALAQYVNDRPYAASSLLAVALSTVFRSALRGVCESRPERAAEPLPLRIELPAVPARGGAELVRGIFGPLGWTSVDVRPIALDERFPDWGESRYVRLVLEGELRLADALNQLYVLLPVLDDAKHYWVSPDEVDKLLRAGEGWLADHPEQKLITSRYLSRRWGLTRQAMERLEMVRLAEAEGLAIEDLDNAVDESTDTEEKPVPLAEQRREAILAALREAGAGRVLDLGCGQGQLVQALLKDVRFTEIVGVDVSVRALTIAGRRLRLDRMGERQAARVRLIQGSLTYTDKRLGGYDAAVLSEVIEHLDLPRLPALEYAVFRSARPRTVVVTTPNVEYNVRWETLPAGHVRHGDHRFEWTREEFRRWAETVAEREGYRVALVPVGPDDPEVGPPTQMAVFTREGDERTDPGTPAGTKTETGTDTKSDTGTGTELKETGTKETKSA
>NZ_CP016559.1|WP_003955589.1|1248966_1249251_+|hypothetical-protein
MSEMAYSIGEGPATRVSLSLPGGTAEAIQARVGKREFSAFIAAAVERELRGRVLDEYPADYESREGPVSEQARQRARQVFDEVFDEEDQRPAAS

Crispr_ID: NZ_CP016559_4

• CRISPR_ID: NZ_CP016559_4
• CRISPR_location: 1391642-1391730
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_4

Consensus_repeat	Method
CGCACGGCCGGTCACGGGAGTCCGGCCG	CRISPRCasFinder

spacers of NZ_CP016559_4

>4.1|1391670|33|NZ_CP016559|CRISPRCasFinder
GTCACGGGGTCCGGCCGCCGTACGTCCGTACGC

CRISPR arrays and Neighbor proteins around NZ_CP016559_4

CRISPR arrays

The CRISPR arrays of NZ_CP016559_4

>merge|NZ_CP016559|4|1391642-1391730|CRISPRCasFinder
CGCACGGCCGGTCACGGGAGTCCGGCCGGTCACGGGGTCCGGCCGCCGTACGTCCGTACGCCGCACGGCCGGTCACGGGGTCCGGCCGC

>NZ_CP016559|4|3|1391642-1391730|CRISPRCasFinder
CGCACGGCCGGTCACGGGAGTCCGGCCG	GTCACGGGGTCCGGCCGCCGTACGTCCGTACGC
CGCACGGCCGGTCACGGGGTCCGGCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003956124.1|1398586_1399795_-|citrate-synthase/methylcitrate-synthase	unknown	unknown	gnl|CDD|99862
NZ_CP016559.1|WP_003962122.1|1384463_1385078_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003956125.1|1397353_1398574_-|GTP-binding-protein	unknown	unknown	gnl|CDD|223597
NZ_CP016559.1|WP_003956137.1|1378434_1379958_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187556
NZ_CP016559.1|WP_003956119.1|1406936_1407167_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003956127.1|1393129_1394548_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP016559.1|WP_009997751.1|1394787_1397235_+|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
NZ_CP016559.1|WP_003962120.1|1389466_1390138_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP016559.1|WP_003962124.1|1382393_1383134_-|thymidine-kinase	unknown	unknown	gnl|CDD|235272
NZ_CP016559.1|WP_003956120.1|1404381_1406499_-|type-IIA-DNA-topoisomerase-subunit-B	unknown	unknown	gnl|CDD|235501
NZ_CP016559.1|WP_003956131.1|1388945_1389227_+|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|273389
NZ_CP016559.1|WP_003962126.1|1380443_1381280_-|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NZ_CP016559.1|WP_003962118.1|1391738_1393106_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP016559.1|WP_065757089.1|1390454_1391234_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP016559.1|WP_003962114.1|1401804_1403520_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|225827
NZ_CP016559.1|WP_065757088.1|1385125_1388737_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|131764
NZ_CP016559.1|WP_003962125.1|1381639_1382419_+|VOC-family-protein	unknown	unknown	gnl|CDD|319911
NZ_CP016559.1|WP_065757232.1|1399898_1401197_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|376311
NZ_CP016559.1|WP_003962123.1|1383258_1384464_-|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|366747
NZ_CP016559.1|WP_003962113.1|1403516_1404296_+|response-regulator	unknown	unknown	gnl|CDD|226931

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003956124.1|1398586_1399795_-|citrate-synthase/methylcitrate-synthase	gnl|CDD|99862	cd06109, BsCS-I_like, Bacillus subtilis (Bs) citrate synthase CS-I_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and OAA to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. The overall CS reaction is thought to proceed through three partial reactions and involves both closed and open conformational forms of the enzyme: a) the carbanion or equivalent is generated from AcCoA by base abstraction of a proton, b) the nucleophilic attack of this carbanion on OAA to generate citryl-CoA, and c) the hydrolysis of citryl-CoA to produce citrate and CoA. This group contains proteins similar to BsCS-I, one of two CS isozymes in the gram-positive B. subtilis. The majority of CS activity in B. subtilis is provided by the other isozyme, BsCS-II (not included in this group). BsCS-I has a lower catalytic activity than BsCS-II, and has a Glu in place of a key catalytic Asp residue. This change is conserved in other members of this group. For E. coli CS (not included in this group), site directed mutagenesis of the key Asp residue to a Glu converts the enzyme into citryl-CoA lyase which cleaves citryl-CoA to AcCoA and OAA. A null mutation in the gene encoding BsCS-I (citA) had little effect on B. subtilis CS activity or on sporulation. However, disruption of the citA gene in a strain null for the gene encoding BsCS-II resulted in a sporulation deficiency, a characteristic of strains defective in the Krebs cycle. This group contains proteins which functions exclusively as either a CS or a 2MCS, as well as those with relaxed specificity which have dual functions as both a CS and a 2MCS. Many of the gram-negative species represented in this group have a second CS isozyme which is in another group.	5.67748e-155
NZ_CP016559.1|WP_003956127.1|1393129_1394548_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	2.52586e-78
NZ_CP016559.1|WP_003956125.1|1397353_1398574_-|GTP-binding-protein	gnl|CDD|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	5.81605e-67
NZ_CP016559.1|WP_003962123.1|1383258_1384464_-|alkaline-phosphatase-family-protein	gnl|CDD|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	4.79367e-44
NZ_CP016559.1|WP_009997751.1|1394787_1397235_+|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
NZ_CP016559.1|WP_003962120.1|1389466_1390138_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	6.36906e-38
NZ_CP016559.1|WP_003962124.1|1382393_1383134_-|thymidine-kinase	gnl|CDD|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	3.6299e-86
NZ_CP016559.1|WP_003956120.1|1404381_1406499_-|type-IIA-DNA-topoisomerase-subunit-B	gnl|CDD|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
NZ_CP016559.1|WP_003956131.1|1388945_1389227_+|HPr-family-phosphocarrier-protein	gnl|CDD|273389	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family. The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS].	5.07925e-22
NZ_CP016559.1|WP_003962126.1|1380443_1381280_-|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	3.16782e-78
NZ_CP016559.1|WP_003962118.1|1391738_1393106_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	3.76755e-55
NZ_CP016559.1|WP_065757089.1|1390454_1391234_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	8.15403e-37
NZ_CP016559.1|WP_003962114.1|1401804_1403520_+|sensor-histidine-kinase	gnl|CDD|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	7.31187e-135
NZ_CP016559.1|WP_065757088.1|1385125_1388737_-|GNAT-family-N-acetyltransferase	gnl|CDD|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	6.33997e-105
NZ_CP016559.1|WP_003962125.1|1381639_1382419_+|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.29687e-25
NZ_CP016559.1|WP_065757232.1|1399898_1401197_+|helix-turn-helix-domain-containing-protein	gnl|CDD|376311	pfam00285, Citrate_synt, Citrate synthase, C-terminal domain. This is the long, C-terminal part of the enzyme.	5.92559e-67
NZ_CP016559.1|WP_003956137.1|1378434_1379958_-|SDR-family-oxidoreductase	gnl|CDD|187556	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2. This subgroup contains atypical SDRs, one member is identified as Escherichia coli protein ybjT, function unknown. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that generally matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.18216e-137
NZ_CP016559.1|WP_003962113.1|1403516_1404296_+|response-regulator	gnl|CDD|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.53895e-71

Protein sequences

>NZ_CP016559.1|WP_065757089.1|1390454_1391234_-|M23-family-metallopeptidase
MALTRSTGKHRAPSRATLRGANIARAATLATTGVCGSLATPALVAESTAPAASSEDTGTFMILAADAEADSLADEVADQAVTQKREAIAREEAAEEARRKAEAREREAQEARERAAREAERERLMNTYQAPVSGGVSTAYQTGGAYWSSGSHSGIDFHASYGTSVVSVGAGTVVEAGWGGAYGNNVVIRMNDGSYTQYGHLAAVHVAAGQSVLPGQQIGLAGSTGNSTGAHLHFEARTGAEYGSDVDPVAYLRSHGVHV
>NZ_CP016559.1|WP_003962120.1|1389466_1390138_-|GntR-family-transcriptional-regulator
MRVPAHSVCTAIRDDIVSGVFPRGAKLTEEQLARRYGVSRIPVREALRTLEAEGFVVTQRHAGAHVAELSEQEAADLLEVRMLLEPLGAARAARRRTEAHLRVLRGLVRLGQERARRGQAEDLRALGGWFHETLAQASVSPGLIALLTQLRHKIAWMYAVEQPAEPVAYWAEHGAILDAVARGDAERARALTALHAERNAGAHRLRTSHPVRPPRRGLAPARP
>NZ_CP016559.1|WP_003956131.1|1388945_1389227_+|HPr-family-phosphocarrier-protein
MAERRVNVGWAEGLHARPASLFVRAAAASGVPVTIAKADGNPVNAASMLAVLGLGARGGEEIVLASEAEGADAALDRLAKLVAEGLEELPETV
>NZ_CP016559.1|WP_065757088.1|1385125_1388737_-|GNAT-family-N-acetyltransferase
MRTRPEQTYPDHWEADVVLRDGSTARIRPITPDDAGRLVSFYEQVSDESKYYRFFAPYPRLTDRDVHRFTHHDYVDRVGLAVTVGGEIIATVRYDRIDGLGRPASAPAEEAEVAFLVQDAHQGRGVASALLEHIAAVARERGVRRFVAEVLPANTKMIKVFRDAGYTQRRSFEDGSVHLTLDLEPTEKSLAVQRGREQRAEARSVQRLLAPGSVAVIGTGRASGGMGRTVLRNILDSGYRGRLYAVNRAFGGGRTEVEGVPAFRSVAEIAAATGEAVDLAVVAVPVERVPEAVADCGEHGVRGLVVLTAGYAESGAEGRRRQRELVRRARSYGMRIIGPNSLGIISTADAVRLNASLAPGSPAPGRIGLFTQSGAIGIALLSELHRRGAGLSTFISSGNRADVSGNDFLQYWYDDPDTDVVLMYLESIGNPRKFTRLARRTAAVKPLVVVKGARHSGSEPPGHAVPATRIPDAAVGALLRQAGVIRVDTVTELIDVGLLLAGQPLPAGPRVAILGNSESLGLLTYDACLTEGLRPQPPLDLTTDATPADFRAALARALADDGCDAVVVTAIPWVGEHGATESGDGEVLARALRAAVAESGRTKPVAVVHVELRGLAEALAAVRGSTDDAPAPPGDGGLVGEVRRSGAPGASVSAPEARGSGLPSAAGRAPAPGGPVPSAPGARPSVPPGGGPAPSSDGSVPGADARSGGAAAPVSSARGDGGPVREVRSSGGGPGPLSGGSPRGGGEGVPVSGVPGEPVHGADTPSGGAAVSVPGGGPVPTGPEVPVSAAPGAPASAPEARGSGLPSSAPGAGPSVPPGDGSGPLSGGSPRGGGEGVPVSGSSEGSVHGADARSTGDGGAVSVPGGGPVPPGASAARGDGGPVREVRSSAPSGGGSGLSSGGSVPEAGAGPGEWDGGGRIPGYPAAERAVRALSEAVRYARWRRQAAEPGRVPEFEDIDEVGAAALIERLLDEDGSGTLPAADAHALLGRYGIRVRAALPAPGPDDAAGAAARLGYPVALKTTAPQLRHRPDLGGVRLDLADEAQLRLAYRELTEQLGPPDALRPVVQSMAPRGVDTVVRAAVDPAVDAVLSFGLAGAASELLGDTSHRLVPATVRDAAELVRGIRTAPLLFGWRGSAPVDTPALEELLLRVSRLVDGHPEVVSISLEPVVVAQRGLSVLGASVRLAPAATFTDLGPRRLPSY
>NZ_CP016559.1|WP_003962122.1|1384463_1385078_-|hypothetical-protein
MDRMAKTGTTTQGLRAAIERSGYYPALVAEAVEAAVGGEQIGSYLVHQETTFDANEVRRHVTVLVLTGNRFIVSHTDEQAADSSSPTPYATTSTESVKLDRISSVVVSRVVANPEAYTPGTLPREVVLTIGWGAVSRLDLEPAACGDPNCEADHGYTGSSTADDLSLRVSEAGDGPDTVRQTLAFAQALSEATAATATPSGATR
>NZ_CP016559.1|WP_003962123.1|1383258_1384464_-|alkaline-phosphatase-family-protein
MVQPATPAAVWPDEPEPLAVGSAPVPAYGRGSLADLLPTLAAGLGVPGLEPLIGELTPADRNCVFLIDGLGWEQIRNHPADAPYLTSLLPTSCGGTGRPITAGFPATTATSLASVGTGQHPGAHGLAGYTVRDPATGELMNQLRWRPWTDPHTWQPYPTVFRLAHAAGVHTAQVSSPIFEDTPLTQIALSGGTFLGRLGGEERMDLAAEQLAAGDRSLVYTYYSEVDGKGHRFGVDSDAWRGQLAYVDRLVQRLAEQLPPRSALYVTADHGMVDVPFDEESRIDFDEDWELRAGVALLGGEGRARHVYAVPGAESDVLAVWREVLGDRFWVASRAEAIAAGWFGPSVDERVHGRIGDVIAAARDDVAITASVSERHESAMVGLHGSMTPAEQLVPLLEVRA
>NZ_CP016559.1|WP_003962124.1|1382393_1383134_-|thymidine-kinase
MSELVFFSGTMDCGKSTLALQIEHNRSARGLQGVIFTRDDRAGEGKLSSRLGLVTDAVEAGESFDVYAHLVDRLSQGGRCDYVIADEAQFFAPEQIDQLARVVDDLGLDVFAFGITTDFRSKLFPGSQRLVELADRIEVLQVEALCWCGARATHNARTVGGMMVVEGAQVVIGDVDAIDEVGYEVLCRRHHRRRMTAASARAAALSPDVLPVDAPAPVAAASGAVRSVAATSGGPVGSVSRPTVRS
>NZ_CP016559.1|WP_003962125.1|1381639_1382419_+|VOC-family-protein
MTEATRHTPGTPCWASLMVHRLEATQSFYHELFGWDFSPGPQPLGPYVRARLDGKDVAGLGQLPRGRQAPMSWTPYLATDSTDSCAETARCSGATVAVGPLDAGDAGRLAIVADPVGAIFGMWQQGALPGTAVRGAHGTPVWHELLTVESAAVRKFYETAFGYEVEEARSPGGGSGADRVTLRIDGRPVAVVHGLGRLPQGRGSHWMISFEVDDADRAARRVTELGGRVVDAPEDGPRGRTATVADREGAMFRIVRSGG
>NZ_CP016559.1|WP_003962126.1|1380443_1381280_-|sulfurtransferase
MNAISPIISADELADALAGPRPPVLLDVRYRLGGPNGRPEYEAGHIPGAVFVDLDKELAAPPGAGGRHPLPDPEVFGAAMRRAGVRADSPVVVHDADKGWGAARAWWLLRWAGHRDVRVLDGGLGAWTGPLETGTGRRSDEGDFTPAPGALPLLTADTAAAWAREGLLLDARAGERYRGEVEPIDAVAGHIPGSVSAPTDGNLDEHGRFLPPATLRERFTALGAESDEVAVYCGSGVSAAQQAIALELAGFVPALYAGSWSEWSRDPARPVATGPLPG
>NZ_CP016559.1|WP_003956137.1|1378434_1379958_-|SDR-family-oxidoreductase
MTADTPVAGRPPGQRPRCLVTGATGYIGGRLVPELLAAGHRVRTLARSPEKLRDHPWAADVESVRGDVLDARSVRTALTGVDVAYYLVHSLNTGRDFERTDREAARIFAAEARAAGVRRIVYLGGLTPAGVPEHRLSPHLRSRAEVGRIFLDGEVPTAVLRAAVIIGSGSASFEMLRYLTERLPVMVTPSWVRTRVQPIGVRDVLRYLLVCATLPDDVHRAFDIGGADVLTYREMMRGYAAVAGLPRRLIVPVPVLTPRLSSHWVGLVTPVPHSVARPLTESLRYEVVCREHDIARWAPDGPGRPLGFRGALTLAVQRVREANVVTRWSSAAVPGAPSDPLPTDPDWAGGSLYTDRRELPVDASPQALWRVIEGIGGDNGWYSFPLAWAVRGWLDRFAGGVGLRRGRRDAQRLRVGDSLDFWRVEEIEPGRLLRLRAEMRLPGLAWLELYADRDAEGRTRYRQRALFHPRGLLGHAYWWSVAPFHSVVFGGMARNIARAAVRRGEGA
>NZ_CP016559.1|WP_003962118.1|1391738_1393106_-|insulinase-family-protein
MEFHPQPQAGRARPWAFPAPERGALDNGLTVLHCHRPGQQVVAVEILLDAPLDAEPEGLDGIATIMARALSEGTDKRSAEEFAAELERCGATLDAHADHSGVRISLEVPASRLPKGLGLLAEALRAPAFLDTEIERLVRNRLDEIPHETANPSRRAAKELYKQLFPASLRMSRPRQGSEETVARIDSTAVRAFFETHVRPATATLVVVGDFTGIDLDAVLADTLGEWTGEAGALRPVPAVSADDAGRVIVVDRPGAVQTQLLIGRVGPDRHDRVWAAQVLGAYCLGGTLTSRLDRVLREEKGYTYGVRAFGQVLRSAPDGSGASLLAISGSVDTPNTGPALEDLWQVLRVLAAEGLTDAERDAAVQNLVGVAPLRYETAASVAGTLADQVEQYLPDDYQARLYARLAETGTVEATAAVVSAFPVDRLVTVLVGDAAQIAAPVEALGIGKVTVVTG
>NZ_CP016559.1|WP_003956127.1|1393129_1394548_-|insulinase-family-protein
MHTVAVLGKQHPLSIAIEGTYMPMGHTATARAGSGGLTATEHRLANGLRVVLSEDHLAPVAAVCLWYDVGSRHEVKGRTGLAHLFEHLMFQGSKQVHGNGHFELVQGAGGSLNGTTSFERTNYFETMPAHQLELALWLEADRMGSLLAALDDESMENQRDVVKNERRQRYDNVPYGTAFEKLTALAYPEGHPYHHTPIGSMADLDAATLEDARAFFRTYYAPNNAVLSVVGDIDPEQTLAWVEKYFGSIPGHDGKPAPRDGSLPDVIGEQLREVVEEDVPARALMAAYRLPHDGTRECDAVDLALTVLGGGESSRLHNRLVRRDRTAVGAGFGLLRLAGAPSLGWLDVKISGGVEVGTIEVAVDEELARFAADGPTPEEMERAQAQLEREWLDRLSTVAGRADELCRYAVLFGDPQLALTAVERILTVTADEVREAAAARLRPDNRAVLVYEPLAAEAAGQSDETDEEGAGQ
>NZ_CP016559.1|WP_009997751.1|1394787_1397235_+|DNA-topoisomerase-IV-subunit-A
MARRSTKTPQPDFEEKILDIDVVDEMQGSFLEYAYSVIYSRALPDARDGMKPVQRRIVYQMNEMGLRPDRGYVKCARVVGEVMGKLHPHGDASIYDALVRMAQPFSMRVPLVDGHGNFGSLGNDDPPAAMRYTECRMADATSLMTESIDEDTVDFAPNYDGQEQEPVALPAAYPNLLVNGSSGIAVGMATNMPPHNLGEVIAAARHLIRYPGADLEALMRFVPGPDLPTGGRVVGLSGIRDAYETGRGTFKIRATTSVEDVTARRKGIVVTELPFSVGPEKVISKIKDLVGSKKLQGIADVKDLTDRAHGLRLVIEIKNGFVPEAVLEQLYKLTPMEESFGINNVALVDGQPLTLGLKELLEVYLDHRFTVVRRRSEFRRGRRRDRLHLVEGLLVALVDIDEVIRLIRSSENSAQAKQRLIERFGLSEVQTQYILDTPLRRLTKFDRIELESERDRLMDEIAALTRILESDAELRKLVSGELASVAKKFGTERRTVLLESGAVPAPAVALEVADDPCRVLLSSTGLLARTVTGDPLPEPGPKRARHDLVVSSVTATARGDIGAVTSAGRLLRVAVIDLPQLPQTATAPTLSGGAPLSEFLSLEADETVICLTTLDESSQGLALGTLQGVVKRVVPDYPANKDELEVFSLKEGDRIVGGAELRTGEEDLVFITSDAQLLRYPAAQVRPQGRAAGGMAGVKLADGARVLSFTAVDPAAEAVVFTAAGSTGALDDSVTTVKLTPFDQYPRKGRATGGVRCQRFLKGEDVLLLAWAGEAPARAAQANGVPAELPEQDPRRDGSGTPPVSAVAVLAGPPR
>NZ_CP016559.1|WP_003956125.1|1397353_1398574_-|GTP-binding-protein
MSPVPPPSKQIPVIVLAGFLGSGKTTLLNHLLRACRGTRIGAIVNDFGSIEIDAMTVAGQLGDSTVSLGNGCLCCAVDASELDVFLEKLARPAARLDVIVIEASGLAEPRELVRMVLAAANERVVYGGLVEVVDAAEFDATRERHPEIDRHLAIADLVVLNKTDRVDGAARARLRSALAALAPGAAAVESVYGRVDPELFFDRRPAGERVGQLAFDDLLTADDAHPGAGTCDGSCTGSCDAGAGHPHASYDSVAFTAGRPLHPRRLLDFLDSRPEGLYRIKGFVDFGAADPRNRYAVHAVGRFLRFLPEPWPAGAERRTDLVLIGSGIDAPALRTALDRTPVTDDPADLPDERSMWGVLRYVADVPDVPDVPDASGAPGPAAAEPAMAEPAAEWTGEWTGETVPGG
>NZ_CP016559.1|WP_003956124.1|1398586_1399795_-|citrate-synthase/methylcitrate-synthase
MQSAEGTPTTGTTPTTEATPAAGGVRAVPRGLAGVVVTDTGLGDVRGREGFYHYRQYSAVELAESRTFEDVWHLMFHGRLPDAAEGAAFLAHTARLRRLPDAVRAALPAIAHAGPASGPLAGLRTALSLLGAATGMRPVYDLDPDARRADALTACAAVPTLLTALHRLSRGLEPVEPRTDLPYAANYLYMLSGTEPEPARARAVERYLVSTVDHGFNASTFTGRVIASTGADVVAGLTGAIGALSGPLHGGAPSRALDTLDAIGTPDRIRPWITERVLAGSRIMGFGHPVYRTEDPRSRMLRSVAEGFGGPLVEFAVQVEKEVVAILAELKPGRELHTNVEFYAGVVMELCGLPREMFTPTFCAARVVGWSANILEQAADSKIIRPAARYVGPPPPQPVPAV
>NZ_CP016559.1|WP_065757232.1|1399898_1401197_+|helix-turn-helix-domain-containing-protein
MTDHAAEAERLTTREAAERLGVKPATLYAYVSRGLLTSRRGPGGRGSTFDPQEVDALVRRNRREAASGGEPTQRIRTGLTLIDADRYWFRGVDAVELARRYPYETVAEWLWTGTLRPSVRFTAPPDALAAARRAVAALPANSGSTDRLRVAAIAAAVTDPVRFDLGRDAVLGSARMLIPTLVEALPPTGAAARAGTAAEAAGPETGGPSDGAVPIARRLWPRLTAAEPGPAAVRVLDLALALLADHDLAASTLAVRVAASARAHPYAVVSAGLGALDGPLHGAASDLTHRMLTEVLERGSAAAVVADHLRAGRRVPGLGHRLYPGRDPRAEALLAALEPLPEARAALEAAREVEAVTARQMALNANVDLALGVLSVSFGMPAEAGETVFAVARTAGWIAHALEEYEERPLRLRPSGQYTGPRPPRPLPEPEH
>NZ_CP016559.1|WP_003962114.1|1401804_1403520_+|sensor-histidine-kinase
MSPEPTAPPRRRRIGWPQRVFSQVLLMQLAIATGVTVLATGFFLAPLSAQLDDQAMRRALAIAQTAASPQVADGLATTRPTATGPVQTEAERIRRTTGAEYVVIMDMTGVRWSHTSPEQIGRLVSTDPSAALAGREVMEIDDGTLGRSARGKVPLRDDAGRIIGAVSVGIEYDSVRDRLFSAIPGMLLYAGGALAAGAIAAYLISRRLQRQTHDLAFSDISALLAEREAMLHGIREGVVALDATGRIRLMNDEAQRLLGLESDGRGLPLDEVLGAGRTADVLAGRVTGEDLLAVRGHRVLITNRMPTDDGGAVATLRDRTELERLGRELDSTRGLIDALRAQDHEHANRMHTLLGLLELEMHDEAVSFVTEVVGVHRATAEQVTEKIHDPLLASLLVGKATVAAERGVSLRIAPGTLLPDRVVDPRGLVTVLGNLVDNAMDAAAGSAEPGIEVELSSEGRTAVLRVADTGPGVPPEQREQIFTEGWTTKELPAHGKRGLGLALVRRLAERQGGSALVREAEGGGAEFVVVLPEALAPEALTDGTPTDEGHEGSPDGTTAHEPKTATAAEAR
>NZ_CP016559.1|WP_003962113.1|1403516_1404296_+|response-regulator
MTNGSTVGNGRVGTPATDPTGAGGPPGRPAPEGMIDVLVVDDDIRVAGINAAYVAKVPGFRVSAEAHSAAEALARIADSPADLVLMDHYLPDGNGLAVVRELRRLGHQTDVIMVTAARDVATVQAAMRHGALQYLVKPFNFAGLRTKLEAYAGLRRTLGGGGEAEQAEVDRIFGALSAGAAAPDLPKGHSPTTAEVVRQVLLTAEGPLSTQLIAERAGVSRQTAQRYLKLLERTGRVRLSLKYGETGRPEHRYLWSARP
>NZ_CP016559.1|WP_003956120.1|1404381_1406499_-|type-IIA-DNA-topoisomerase-subunit-B
MTAETSVPSTTLLTAERDGSNYTARHLLVLEGLEAVRKRPGMYIGSTDSRGLMHCLWEIIDNSVDEALGGYCDHIEVILHDDGSVEVRDNGRGIPVDVEPKTGLSGVEVVMTKLHAGGKFGGGSYAASGGLHGVGASVVNALSARLDVEVDRNGSTHAISFRRGVPGIFTEQGPDAPFDPANGLRKGKRVPKTRTGTRVRYWTDRQIFLKEARLALETLHQRARQTAFLVPGLTIVVRDERDLAGEGKSQEIFRFDGGISEFCEYLAQDKAVCDVLRLTGQGTFKETVPVLDDRGHMTPTEVTRELGVDIALRWGTGYDTAVRSFVNIIATPKGGTHVTGFERSVTKTVNEVLRSAKLLRVAEDDIVKDDALEGLTAVVTVRLAEPQFEGQTKEVLGTSAANRIVSNVVARELKAFLTSTKRDAKAQARAVLEKAVAAARTRIAARQHKEAQRRKTALETSSLPAKLADCRSDDVERSELFIVEGDSALGTAKLARNSEFQALLPIRGKILNVQKSSVSDMLKNAECGAIIQVIGAGSGRTFDLDAARYGKIVLLVDADVDGAHIRCLLLTLFQRYMRPMVEAGRVFAAVPPLHRIELVQPKKGQDKYVYTYSDNELRQTLLEFQRKGVRYKDSIQRYKGLGEMDADQLAETTMDPRHRTLRRINIGDLDAAEQVFDLLMGNEVAPRKEFITSSAATLDRSRIDA
>NZ_CP016559.1|WP_003956119.1|1406936_1407167_+|hypothetical-protein
MTTVLTPASPLTAADRCDRCGAQAYLRVVLTSGGELLFCAHHGRKFEPELKKIAAEIQDETDRLTAVPAGAGHEDH

Crispr_ID: NZ_CP016559_5

• CRISPR_ID: NZ_CP016559_5
• CRISPR_location: 2343208-2343328
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_5

Consensus_repeat	Method
CTTTCGGCAGCCACACGCCCCGATGGCTCACTCGCC	CRISPRCasFinder

spacers of NZ_CP016559_5

>5.1|2343244|49|NZ_CP016559|CRISPRCasFinder
GCAGAGGCAGGGCAAACGCCCGGCCCAACAGACAGGCGGGCGCTCTCCG

CRISPR arrays and Neighbor proteins around NZ_CP016559_5

CRISPR arrays

The CRISPR arrays of NZ_CP016559_5

>merge|NZ_CP016559|5|2343208-2343328|CRISPRCasFinder
CTTTCGGCAGCCACACGCCCCGATGGCTCACTCGCCGCAGAGGCAGGGCAAACGCCCGGCCCAACAGACAGGCGGGCGCTCTCCGCTTTCGGCAGCCACGCGCCCCGATGGCTCACTCGCC

>NZ_CP016559|5|4|2343208-2343328|CRISPRCasFinder
CTTTCGGCAGCCACACGCCCCGATGGCTCACTCGCC	GCAGAGGCAGGGCAAACGCCCGGCCCAACAGACAGGCGGGCGCTCTCCG
CTTTCGGCAGCCACGCGCCCCGATGGCTCACTCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_009997429.1|2333583_2334918_-|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NZ_CP016559.1|WP_003955222.1|2344431_2345784_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003955226.1|2338898_2339933_+|L-glyceraldehyde-3-phosphate-reductase	unknown	unknown	gnl|CDD|381376
NZ_CP016559.1|WP_003958266.1|2351274_2352162_-|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|224975
NZ_CP016559.1|WP_003961670.1|2342231_2343017_-|prepilin-peptidase	unknown	unknown	gnl|CDD|224900
NZ_CP016559.1|WP_003961668.1|2346676_2347300_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003961669.1|2343560_2343929_+|DUF192-domain-containing-protein	unknown	unknown	gnl|CDD|376876
NZ_CP016559.1|WP_029183026.1|2337868_2338630_-|isoprenyl-transferase	unknown	unknown	gnl|CDD|237825
NZ_CP016559.1|WP_003955219.1|2347362_2348034_-|hypothetical-protein	unknown	unknown	gnl|CDD|379164
NZ_CP016559.1|WP_003955221.1|2345924_2346677_-|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NZ_CP016559.1|WP_009997423.1|2348087_2348336_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_009997428.1|2335033_2335777_-|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl|CDD|366654
NZ_CP016559.1|WP_003955232.1|2332387_2332942_+|peroxiredoxin	unknown	unknown	gnl|CDD|239313
NZ_CP016559.1|WP_003955228.1|2336193_2337516_-|PhoH-family-protein	unknown	unknown	gnl|CDD|224787
NZ_CP016559.1|WP_003961665.1|2349601_2351197_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP016559.1|WP_003958265.1|2352172_2353114_-|membrane-protein	unknown	unknown	gnl|CDD|227300
NZ_CP016559.1|WP_003955233.1|2331179_2332121_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|182999
NZ_CP016559.1|WP_003955225.1|2340571_2342044_-|DUF2079-domain-containing-protein	unknown	unknown	gnl|CDD|370724
NZ_CP016559.1|WP_003955231.1|2332946_2333483_+|alkyl-hydroperoxide-reductase	unknown	unknown	gnl|CDD|129859
NZ_CP016559.1|WP_009997422.1|2348576_2349551_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|381090

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_009997429.1|2333583_2334918_-|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.41631e-57
NZ_CP016559.1|WP_003955219.1|2347362_2348034_-|hypothetical-protein	gnl|CDD|379164	pfam13400, Tad, Putative Flp pilus-assembly TadE/G-like. This is an N-terminal domain on a family of putative Flp pilus-assembly proteins. The exact function is not known. The Flp-pilus biogenesis genes include the Tad genes, and some members of this family are putatively assigned as being TadG.	0.00148409
NZ_CP016559.1|WP_003955226.1|2338898_2339933_+|L-glyceraldehyde-3-phosphate-reductase	gnl|CDD|381376	cd19150, AKR_AKR14A1, Escherichia coli L-glyceraldehyde 3-phosphate reductase (GPR/YghZ/AKR14A1) and similar proteins. Escherichia coli L-glyceraldehyde 3-phosphate reductase (GPR/YghZ), also called GAP reductase, is a founding member of aldo-keto reductase family 14 member A1 (AKR14A1). It catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). It is also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo.	0
NZ_CP016559.1|WP_003958266.1|2351274_2352162_-|type-II-secretion-system-F-family-protein	gnl|CDD|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	1.89327e-15
NZ_CP016559.1|WP_003961670.1|2342231_2343017_-|prepilin-peptidase	gnl|CDD|224900	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	4.18903e-11
NZ_CP016559.1|WP_003961669.1|2343560_2343929_+|DUF192-domain-containing-protein	gnl|CDD|376876	pfam02643, DUF192, Uncharacterized ACR, COG1430. Two structures have been solved for members of this large (>500 members) family of bacterial proteins present mostly in environmental bacteria and metagenomes (distant homologs are also present in several Plasmodium species). TOPSAN analysis for Structure 3pjy shows that there is much similarity with the other solved structure, Structure 3m7a, solved for UniProt:Q2GA55 (Saro_0823), a homolog of Thermotoga maritima TM1668, UniProt:Q9X1Z6., The homolog in Caulobacter crescentus (CC1388), UniProt:Q9A8G6, is associated with CspD, a cold shock protein (CC1387), UniProt:Q9A8G7. However, the genomic context of UniProt:Q2GA55 is most conserved with a putative xylose isomerase, suggesting a possible role in extracellular sugar processing. Saro_0821, UniProt:Q2GA57, is annotated as an AMP-dependent synthetase and ligase. Structure 3m7a structure corresponds to the C-terminal (27-165) fragment of the YP_496102 (Saro_0823) protein and it is structurally unique, as the best hits from Dali have a Z-score of 3.8 (1nt0, 2j1t, 3kq4) and it is thus a likely candidate for a new fold. Interestingly, many of the top Dali hits are involved in sugar metabolism. There are no obvious active site-like cavities on the protein surface of 3m7a (http://www.topsan.org/Proteins/JCSG/).	2.83314e-17
NZ_CP016559.1|WP_029183026.1|2337868_2338630_-|isoprenyl-transferase	gnl|CDD|237825	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional.	4.93959e-158
NZ_CP016559.1|WP_003955221.1|2345924_2346677_-|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	9.89862e-27
NZ_CP016559.1|WP_009997428.1|2335033_2335777_-|transglycosylase-SLT-domain-containing-protein	gnl|CDD|366654	pfam01464, SLT, Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.	1.47501e-05
NZ_CP016559.1|WP_003955232.1|2332387_2332942_+|peroxiredoxin	gnl|CDD|239313	cd03015, PRX_Typ2cys, Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. The functional unit of typical 2-cys PRX is a homodimer. A unique intermolecular redox-active disulfide center is utilized for its activity. Upon reaction with peroxides, its peroxidatic cysteine is oxidized into a sulfenic acid intermediate which is resolved by bonding with the resolving cysteine from the other subunit of the homodimer. This intermolecular disulfide bond is then reduced by thioredoxin, tryparedoxin or AhpF. Typical 2-cys PRXs, like 1-cys PRXs, form decamers which are stabilized by reduction of the active site cysteine. Typical 2-cys PRX interacts through beta strands at one edge of the monomer (B-type interface) to form the functional homodimer, and uses an A-type interface (similar to the dimeric interface in atypical 2-cys PRX and PRX5) at the opposite end of the monomer to form the stable decameric (pentamer of dimers) structure.	3.93723e-81
NZ_CP016559.1|WP_003955228.1|2336193_2337516_-|PhoH-family-protein	gnl|CDD|224787	COG1875, COG1875, NYN ribonuclease and ATPase of PhoH family domains [General function prediction only].	0
NZ_CP016559.1|WP_003961665.1|2349601_2351197_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	5.74237e-35
NZ_CP016559.1|WP_003958265.1|2352172_2353114_-|membrane-protein	gnl|CDD|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	8.76198e-24
NZ_CP016559.1|WP_003955233.1|2331179_2332121_-|LysR-family-transcriptional-regulator	gnl|CDD|182999	PRK11151, PRK11151, DNA-binding transcriptional regulator OxyR; Provisional.	3.80145e-74
NZ_CP016559.1|WP_003955225.1|2340571_2342044_-|DUF2079-domain-containing-protein	gnl|CDD|370724	pfam09852, DUF2079, Predicted membrane protein (DUF2079). This domain, found in various hypothetical prokaryotic proteins, has no known function.	2.04121e-67
NZ_CP016559.1|WP_003955231.1|2332946_2333483_+|alkyl-hydroperoxide-reductase	gnl|CDD|129859	TIGR00777, AhpD_protein., alkylhydroperoxidase, AhpD family. Members of this family are alkylhydroperoxidases, which catalyze the reduction of peroxides to their corresponding alcohols via oxidation of cysteine residues. In these alkylhydroperoxidases, the cysteines are located in a conserved -CXXC- motif located towards the COOH terminus. In Mycobacterium tuberculosis, two non-homologous alkylhydroperoxidases, AhpD and AhpC, are found in the same operon. [Cellular processes, Detoxification].	2.14087e-91
NZ_CP016559.1|WP_009997422.1|2348576_2349551_-|response-regulator-transcription-factor	gnl|CDD|381090	cd17535, REC_NarL-like, phosphoacceptor receiver (REC) domain of NarL (Nitrate/Nitrite response regulator L) family response regulators. The NarL family is one of the more abundant families of DNA-binding response regulators (RRs). Members of the NarL family contain a REC domain and a helix-turn-helix (HTH) DNA-binding output domain, with a majority of members containing a LuxR-type HTH domain. They function as transcriptional regulators. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	9.39799e-31

Protein sequences

>NZ_CP016559.1|WP_003961670.1|2342231_2343017_-|prepilin-peptidase
MTALGPPLTLVAVYPALIVVAALWGAVTGLLIPRAAYRLSVRAGQEWRDTCPDGHPFGGSVRGWLGGVRCALCPVGPGGPGRGAPAAVPVAALACAALAAATGCRPELAVWLALAPFAVLLAVVDRRVHRLPDRLTLPLAAAAAVLLGAAARLPGAAGSWSGALLGGVVLGAAYLALFVIHPGGMGFGDVKLALSLGVVLGWYGWGTLFMGAFAGFLFGSLYGLALMALGRAGRRTAIPFGPFMIGGALAGVLLGALPVAG
>NZ_CP016559.1|WP_003955225.1|2340571_2342044_-|DUF2079-domain-containing-protein
MPAALLPWSWAAVLFTLYTTVAVRRHLLLRTTGYDLGIFEQGIRAYAELRPPVAPLRGEGFNLLGDHFHPALAVLAPLYRLWPSPLCLLAAQSALLAVAVVPLVSWALTALGRRAAHAVALGYGLSWGVASAAAFDFHEVALAVPLLSAAATALGRGRWRAAVAWATPLVLIKEDLGLTLAAVGCVVAWKGPRRLGLLTAAAGVLASAVEIRLLLPALHPAGGYAHGVNLGEGPHTSLLTAVLSAPLDALRPDIKAMTLVLVFAPSALLALRSPIALLAVPTLAWRMLSQNAFHWGTSFHYSAVLMPVVFAGLIDALRPWRTRGAGAGGVRQVRSSLLTALAVTAVLLPSFPLAQLAQRATWRTTAHITAARALLARIPDGASVAASNRLAPQLTSRCEVVLFPAFPVDARLYRYDRERLPRPTAEWIVHDSSAPEAWPYRRGHWPYPAEQQAAELAAAERSYGYRRVAHRDGVTLLRKGPARPAAGDGR
>NZ_CP016559.1|WP_003955226.1|2338898_2339933_+|L-glyceraldehyde-3-phosphate-reductase
MIDSSPYLASGDRYDTMEYRRSGRSGLLLPAVSLGLWHNFGDDRTLESQRAILRRAFDLGVTHFDLANNYGPPPGSAELNFGKLLAQDFAPYRDELIISTKAGYLMHPGPYGEWGSRKYLLSSLDASLRRMGVDYVDVFYSHRFDPHTPLEETMGALASAVQQGKALYVGVSSYNAEQTERAARLLREMGVPALIHQPSYSMINRWIEDDGLLDTLETAGMGCIAYVPLAQGLLTGKYLQGIPEGSRASQGKSLDPALLSDEVVRRLRGLNEIAARRGQSLAQLALSWVLRDPRMTSALIGASSVAQLDENVAALSAAPLTEAELAEIDEFAVDTEGVNIWARR
>NZ_CP016559.1|WP_029183026.1|2337868_2338630_-|isoprenyl-transferase
MNLRDLVYRLYARRVEGRLDHAQVPKHIGVILDGNRRWAKASGGTPEAGHKAGASKIQELLGWCAETDVEVVTLWLLSTDNLDRPEDELVPLLGIIEDAVRALAADGRWRVHHVGTLDLLPSRTQLVLKEAEQDTLDHTGILVNVAVGYGGRQEIADAVRSLLLDHAERGTSVEELAETVDVDLISKHLYTRGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCEVFWPAFRKVDFLRALRDYAARHRRYGN
>NZ_CP016559.1|WP_003955228.1|2336193_2337516_-|PhoH-family-protein
MVNSTKRRLPDRRTYVLDTSVLLADPSAPTRFDEHEVVLPIVVVTELEAKRHHPELGYFARQALRLLDEFRIRYGRLDAPIPLGDLGGTIRVELNHSDPALLPAGYRLGDNDSRILAVARNLQAEGYDVTVVSKDLPLRIKASSVGLLAEEYRAELAITDSGWTGMAELPLTAEQVDLLYGEERLTLPEAGALPVHTGLVLQSERGKALGRVTADGGVRLVRGDREAFGIHGRSAEQRIALDLLLDPEVGIVSLGGRAGTGKSALALCAGLESVLERRQHQKVMVFRPLYAVGGQELGYLPGTEAEKMSPWAQAVFDTLSAVAGREVIEEVLGRGMLEVLPLTHIRGRSLHDAFVIVDEAQSLERNVLLTVLSRVGAGSRVVLTHDVAQRDNLRVGRYDGVVAVVEKLKGHPLFAHVTLTRSERSPIAALVTEMLEDGQI
>NZ_CP016559.1|WP_009997428.1|2335033_2335777_-|transglycosylase-SLT-domain-containing-protein
MSRISVRGFAVASATAVTTVGAVVGVASGNPQPSNQNLETTAADATLLTNIPMGQQAPVQVSSLAQQADAQAAAADTSARKAAEEDARVKAAQSAKDKRAAADAEAKKAAEAKERAEKEKREREERKKAEERASRDAARSGTASFAQQSSYTVAQVQSIARQIIPSGQFQCFSNIVQRESTWNYKAQNPSSGAYGLVQALPGTKMASAGADWRTNPATQIKWGLNYMNERYGSPCGAWSFWQANRWY
>NZ_CP016559.1|WP_009997429.1|2333583_2334918_-|AI-2E-family-transporter
MARLPRWYSGLGAGIVRIAERMNQRREGDEEPGADVLTKGGTEHGDGPADEPEEAADRPDPVTVIPWGIRVAAEAGWRLLVLAGTLWVLMRVISAVQLVVLAFASALLITALLQPTVARLLRIGLPRGLATAVTAIAGFAVMALVGWFVVWQVMENLDTLSDRVREGIQELRLWALEGPFHVSEGQINDLADNLSDTIGSNTEEITSAGLQGVTALMEFLAGALLAMFSTLFLLHDGPRIWQWTLKLVPAQARPGVASAGPRAWATLTAYVRGTVLVALIDAIFIGLGIWFLDVPMAVPLAVFVFLFAFVPLVGAVLSGALAVVVALVTQGVFTALMVLIVVLAVQQIEGHVLQPFILGRAVRVHPLAVVLSVAVGGLIAGIGGAVVAVPLVAVTNTVVVHLRHYGRRQRVAAARALPEPRAEGAPVPPGRADAGAGPPAPEAR
>NZ_CP016559.1|WP_003955231.1|2332946_2333483_+|alkyl-hydroperoxide-reductase
MSLDALKSALPEYAKDLKLNLGSVIGNNEKLTQQQLWGTVLATAIASRSPIVLRELEAEAKAQLSPEAYTAAKAAAAVMAMNNVYYRTRHLLSDPEYGTLRAGLRMNVIGNPGVEKVDFELWSLAVSAINGCGMCLDSHEQVLRKAGVEREVVQEAFKIAAVVQAVGTTLDTEATLSA
>NZ_CP016559.1|WP_003955232.1|2332387_2332942_+|peroxiredoxin
MLTVGDQFPAFELTACVSLEKGKEFEVLTHKSYEGKWKVVFAWPKDFTFVCPTEIAAFGKLNDEFADRDAQVLGFSGDSEFVHHAWRKDHADLRDLPFPMMADAKHELMRDLGIEGEDGYAQRAVFIVDPNNEIQFTMVTAGSVGRNPKEVLRVLDALQTDELCPCNWSKGEDTLDAGSLLAGE
>NZ_CP016559.1|WP_003955233.1|2331179_2332121_-|LysR-family-transcriptional-regulator
MSQAHRVKQPSIAQLRAFTAVAEHLHFRDAAAAIGMSQPALSGAVSALEDVLGVQLLERTTRKVLLSPAGERLAVRARTVLDAVGALMEEAEAVRAPFTGVLRFGVIPTVAPYLLPTVLRLVHDTYPDLDLQVHEEQTASLLDGLTTGRLDLLLLAVPLGVPGVTELPLFDEDFVLVTPGDHWLGGRADLPREALRELPLLLLDEGHCLRDQALDICREAGREDGTPVTTTAAGLPTLVQLVAGGLGVTLLPRTAVEVETGRGGLQTGYFAEPAPARRIALAMRTGAARLSEFEEFATALRGALRPLPVRIAE
>NZ_CP016559.1|WP_003961669.1|2343560_2343929_+|DUF192-domain-containing-protein
MARGRRWRDGGGELWVAGRDTPVPLEIAASRAARRRGLLGRDGITGAMLLTPCGGVHTFRMRFAIDVAYLDRELRVLDLHTLPPGRLGRPRLRARHVLESDGGTMAEWGLRPGTRLRITPAG
>NZ_CP016559.1|WP_003955222.1|2344431_2345784_-|hypothetical-protein
MRRGRTAVAGRTSATGRARVAALRKGIVIGMSCALLHGPASAAEAMAARQAGYRTAPDARPVVGSPSPRAGGPLLTPGTYTDTVSVGDRKFYRVRLDGRSNAYVSAVLAPPPGSRAGATDGIRVSLVSPDGAECSDSNDIVFGTATPLPTADYSTRRIGPGRACQEAGDYLYSVEWIGPTGGAAPRDWRVEIKYMTEPGLRTGSPTPAPPSSRHTHTPDHIPGPERRVEGGSGFNDAARLGHGVWADRLGPGESRFYRVPVDWGQQLFVDARFTGAVAPRRPVYDGVRVTVFNTARGFVENTARAHRTATTRLSLATEPAAFANRTSDRDATSGMRFSGWYYLRVSADRKIPGELPVTLAVGIEGEPHPAPPYAGDPLREGFGVLAEDRAQPPPADQQAAPQDDDDTRELVLTVIGVTGITLGTTLLLGLLAWTALARLGLGRKRGRHAS
>NZ_CP016559.1|WP_003955221.1|2345924_2346677_-|OmpA-family-protein
MGGTTARRPAAPAARRPAALVLAAALLLTGGQLHAATAATAAGPGLRPPAAGADDPVPPPGEDPALPPVEDPALPPVGEAATPLPQIDADNPGLRMREGATLAEPRVLDIVSIVESEGGEERREQTTVSLKFALQAEVLFGRDSHELNPRANSRIAAIAEEIRRNGAKQVRVFGFTDDLGSYRHGRTLSRKRADAVHAMLDGQVEDHTVSYIVRGYSEDFPIADNSTEEGREKNRRVEVSFPTKGSGDGS
>NZ_CP016559.1|WP_003961668.1|2346676_2347300_-|hypothetical-protein
MRKRYGAGAPRAVTAALAAVALGLALTACGGDFGDDGDAPDARNPGAVSTATGAGAQDGQSPEPQGDGPDASERTAEALATVEGSDGFAFTITGAERDEGGFLTVSGTVTNTSDRRLPPPIQWNGQERQVKRTGRSFAGMTLVDKTEKKRYYVLRDTEGYPLTTTGLGVFGAGQSADFFAQFPAPPPETASVELQIPLMPARTIELG
>NZ_CP016559.1|WP_003955219.1|2347362_2348034_-|hypothetical-protein
MVVGLLALALAFFAVGQAGAQRNGTQSGADAAALAAAQESRDGLEDLLAENILDPVFLRDFFDGGAQEQSAPGCAAAGHAAAESLAAANGTALRDCLAPTEGRWGAYVRVESRRAMGDTLLPGVDGDRATATATAVVEPRCGFEPSAGRPGATASPPPPDGPPDGPGDPGSPDEGQEQPEEPAEPVTPGLLRCDDDRDFELDPARPDLLPRMADLFTVRLDRD
>NZ_CP016559.1|WP_009997423.1|2348087_2348336_-|hypothetical-protein
MSKLRSKAVETARRLVAARTADVVRAVRDRRDEGQDSVEYVGVIVLVAAIIAALVGSGVADDIAAGLSSQVQEILNTGGGGE
>NZ_CP016559.1|WP_009997422.1|2348576_2349551_-|response-regulator-transcription-factor
MPDPVHEPSPNRPPPATPVPATAPAPLRIVVADDNPVVRAGLTALLGTRPGLAVVAEAADGRQVCAETLRHRPDVVLLDVRMPGADGISVLPYLVRLAPVLMLTYSRETETVHAALARGAAGYLVHGEFTAEQLITAVGEVAAGRPVFSASAAGVLPAVPSPRGRTRRPSAPAAPPPSVAPSPSFLSSSSSSAASSASAHRRLPSAGRIEAGSLSVLDDDADTATREYVVHPSLSQAIVGHSSAGARRETHGGTVLGELSRREAEVMELIAAGLTNQEIAAACFISQKTVKNHINRIFAKLNTGSRGEAIALWHRLARSQAGPV
>NZ_CP016559.1|WP_003961665.1|2349601_2351197_-|two-component-sensor-histidine-kinase
MNPPAPPPPPSLPLQVNALQALCRQVFGFRLAMIALAVPFALAGTAPGPANWLVGAAVLVTFMTSYALLRDWERFGPVLLRHPWLLGADMAFGALLLVTASPDSTLAYVIICTPLLGGLISGRRGGAVLAVLQSALVAGAYAVNDSADARYTALLLPGLCVLTGVLGSTLRTLMLRFGAAGQALSEARARLAAAGAVEDERARLAREMHDSVAKTLHGLALAAEGLARSADRMDPAAVRDRADLVAHAARRAAAESRALLADLRRDTGLGPGAGPVTAETAAGLPVCAVLDGLRSRTEEFSRRTGVRAVFRRTEPAGPACEPLVPPTVARQLLTIVAEALENAHRHGGPGRVEVCAGRPEGDGGGLRVRVHDDGRGLPPGTTLDGLRRKGRFGLVGMAERAASIGARIQVGAGEDGRGTEVRLDLPLPVPGPPARLSPQDPPSWRSQDPSPRSRPGESPDPPPGPPRPSPSSPLSLSSPPSPFSRRLPSSPPSSPSSPCPPPSPGGAGPPASPGPCGCADSAPRDPLPLLP
>NZ_CP016559.1|WP_003958266.1|2351274_2352162_-|type-II-secretion-system-F-family-protein
MGPLLATLLAFSVYGIFLGVRMYRSDARLPGDLALALEVGATRTTAVGSVIDRLGVRWAPAVLRAMGPGRVDALRRRLDMAGNPGGMTVDRYAARRAVYSLLGLVAAFSMLLRGQLALAAFLLVFGLFWTDVIIRVAIRRRRADIERTLPDFLDVLAVVVSAGLGFRQALERVAEKYEGPWSDELRITLRQMDMGVSRRDAFDQLRRRNDSEQVSMFVTALQQGEELGAPIVDTLIQIATDMRRTDAQNARREAARAVPKSTLVVTLVMLPATMILIVVSFYYGSGVDLGEVLGG
>NZ_CP016559.1|WP_003958265.1|2352172_2353114_-|membrane-protein
MDNLPLLTAGATLLAGAIGVLGVHTYAAGRAQRDALVARMAQTGEPPARTGRRRRFHALDRRLRTTRYGREVEHRIAATGLDLTCGEYTVAVLVLLLVTHLAVGAVFAPFFGVLAALVALWGARNFLEWQRVKRTEAFIAQLPELTRVLANATQAGLSLRTALAMAAEELDDPAGHELGIVADQLAVGQSLDDALGTLAERLPSRELIVLVTTLILANRAGGQVVTSLRNLTQSLEERKETRREVTTTLSQIKVTALAVPLLGLGFLLMINGMTPGALDRMTGSVVGQGATLAAFGLYGLGAFLIRRLSRIQV

Crispr_ID: NZ_CP016559_6

• CRISPR_ID: NZ_CP016559_6
• CRISPR_location: 2503271-2503372
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_6

Consensus_repeat	Method
CGATGCCCCGGCACCCGCCACCG	CRISPRCasFinder

spacers of NZ_CP016559_6

>6.1|2503294|56|NZ_CP016559|CRISPRCasFinder
CGCCCAAGACCACCCTCCCCGGCACCCACCGCGTCAACGACGGTCCCCGGCCCGAA

CRISPR arrays and Neighbor proteins around NZ_CP016559_6

CRISPR arrays

The CRISPR arrays of NZ_CP016559_6

>merge|NZ_CP016559|6|2503271-2503372|CRISPRCasFinder
CGATGCCCCGGCACCCGCCACCGCGCCCAAGACCACCCTCCCCGGCACCCACCGCGTCAACGACGGTCCCCGGCCCGAACGATGCCCCAGCACCCGCCACCG

>NZ_CP016559|6|5|2503271-2503372|CRISPRCasFinder
CGATGCCCCGGCACCCGCCACCG	CGCCCAAGACCACCCTCCCCGGCACCCACCGCGTCAACGACGGTCCCCGGCCCGAA
CGATGCCCCAGCACCCGCCACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003961587.1|2490895_2492236_-|acylneuraminate-cytidylyltransferase	unknown	unknown	gnl|CDD|133006
NZ_CP016559.1|WP_003961577.1|2507472_2509146_-|family-20-glycosylhydrolase	unknown	unknown	gnl|CDD|119334
NZ_CP016559.1|WP_003958940.1|2509695_2510076_+|succinate-dehydrogenase,-cytochrome-b556-subunit	unknown	unknown	gnl|CDD|239581
NZ_CP016559.1|WP_009997365.1|2505178_2505991_-|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NZ_CP016559.1|WP_003958941.1|2510084_2510561_+|succinate-dehydrogenase-hydrophobic-membrane-anchor-subunit	unknown	unknown	gnl|CDD|239580
NZ_CP016559.1|WP_003958943.1|2512340_2513099_+|succinate-dehydrogenase-iron-sulfur-subunit	unknown	unknown	gnl|CDD|235652
NZ_CP016559.1|WP_003961584.1|2494946_2496413_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_009997364.1|2506499_2507099_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003958918.1|2496485_2497151_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366659
NZ_CP016559.1|WP_003961583.1|2500059_2501640_-|methylmalonyl-CoA-mutase	unknown	unknown	gnl|CDD|239652
NZ_CP016559.1|WP_003958922.1|2499310_2499970_-|leucine-efflux-protein-LeuE	unknown	unknown	gnl|CDD|236807
NZ_CP016559.1|WP_003958942.1|2510586_2512341_+|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl|CDD|236185
NZ_CP016559.1|WP_003958917.1|2493966_2494950_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NZ_CP016559.1|WP_009997366.1|2501835_2502816_+|L,D-transpeptidase-family-protein	unknown	unknown	gnl|CDD|341130
NZ_CP016559.1|WP_003961586.1|2492472_2493789_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003958921.1|2498876_2499182_-|DUF1876-domain-containing-protein	unknown	unknown	gnl|CDD|378103
NZ_CP016559.1|WP_003961576.1|2513914_2515420_-|membrane-protein	unknown	unknown	gnl|CDD|277331
NZ_CP016559.1|WP_003958919.1|2497502_2498135_+|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341362
NZ_CP016559.1|WP_003961580.1|2503640_2505179_-|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NZ_CP016559.1|WP_003958944.1|2513275_2513848_+|hypothetical-protein	unknown	unknown	gnl|CDD|370676

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003961587.1|2490895_2492236_-|acylneuraminate-cytidylyltransferase	gnl|CDD|133006	cd02513, CMP-NeuAc_Synthase, CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety. CMP-N-acetylneuraminic acid synthetase (CMP-NeuAc synthetase) or acylneuraminate cytidylyltransferase catalyzes the transfer the CMP moiety of CTP to the anomeric hydroxyl group of NeuAc in the presence of Mg++. It is the second to last step in the sialylation of the oligosaccharide component of glycoconjugates by providing the activated sugar-nucleotide cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), the substrate for sialyltransferases. Eukaryotic CMP-NeuAc synthetases are predominantly located in the nucleus. The activated CMP-Neu5Ac diffuses from the nucleus into the cytoplasm.	1.12125e-74
NZ_CP016559.1|WP_003961576.1|2513914_2515420_-|membrane-protein	gnl|CDD|277331	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain. YkuE is an uncharacterized Bacillus subtilis protein with a C-terminal metallophosphatase domain and an N-terminal twin-arginine (RR) motif. An RR-signal peptide derived from the Bacillus subtilis YkuE protein can direct Tat-dependent secretion of agarase in Streptomyces lividans. This is an indication that YkuE is transported by the Bacillus subtilis Tat (Twin-arginine translocation) pathway machinery. YkuE belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.50861e-76
NZ_CP016559.1|WP_003958940.1|2509695_2510076_+|succinate-dehydrogenase,-cytochrome-b556-subunit	gnl|CDD|239581	cd03501, SQR_TypeA_SdhC_like, Succinate:quinone oxidoreductase (SQR) Type A subfamily, Succinate dehydrogenase C (SdhC)-like subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this subfamily reduce low potential quinones such as menaquinone and thermoplasmaquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Members of this subfamily are similar to the Thermoplasma acidophilum SQR and are classified as Type A because they contain two transmembrane subunits as well as two heme groups. Although there are no structures available for this subfamily, the presence of two hemes has been proven spectroscopically for T. acidophilum. The two membrane anchor subunits are similar to the SdhD and SdhC subunits of bacterial SQRs, which contain heme and quinone binding sites. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the membrane anchor subunits via electron transport through FAD and three iron-sulfur centers. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes.	2.64412e-41
NZ_CP016559.1|WP_009997365.1|2505178_2505991_-|RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	1.83375e-30
NZ_CP016559.1|WP_003958941.1|2510084_2510561_+|succinate-dehydrogenase-hydrophobic-membrane-anchor-subunit	gnl|CDD|239580	cd03500, SQR_TypeA_SdhD_like, Succinate:quinone oxidoreductase (SQR) Type A subfamily, Succinate dehydrogenase D (SdhD)-like subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this subfamily reduce low potential quinones such as menaquinone and thermoplasmaquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Members of this subfamily are similar to the Thermoplasma acidophilum SQR and are classified as Type A because they contain two transmembrane subunits as well as two heme groups. Although there are no structures available for this subfamily, the presence of two hemes has been proven spectroscopically for T. acidophilum. The two membrane anchor subunits are similar to the SdhD and SdhC subunits of bacterial SQRs, which contain heme and quinone binding sites. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the membrane anchor subunits via electron transport through FAD and three iron-sulfur centers. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes.	5.32911e-45
NZ_CP016559.1|WP_003958943.1|2512340_2513099_+|succinate-dehydrogenase-iron-sulfur-subunit	gnl|CDD|235652	PRK05950, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	3.88374e-146
NZ_CP016559.1|WP_003961577.1|2507472_2509146_-|family-20-glycosylhydrolase	gnl|CDD|119334	cd06564, GH20_DspB_LnbB-like, Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins. Dispersin B is a soluble beta-N-acetylglucosamidase found in bacteria that hydrolyzes the beta-1,6-linkages of PGA (poly-beta-(1,6)-N-acetylglucosamine), a major component of the extracellular polysaccharide matrix. Lacto-N-biosidase hydrolyzes lacto-N-biose (LNB) type I oligosaccharides at the nonreducing terminus to produce lacto-N-biose as part of the GNB/LNB (galacto-N-biose/lacto-N-biose I) degradation pathway. The lacto-N-biosidase from Bifidobacterium bifidum has this GH20 domain, a carbohydrate binding module 32, and a bacterial immunoglobulin-like domain 2, as well as a YSIRK signal peptide and a G5 membrane anchor at the N and C termini, respectively. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	2.51786e-79
NZ_CP016559.1|WP_003958918.1|2496485_2497151_-|XRE-family-transcriptional-regulator	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	1.51956e-12
NZ_CP016559.1|WP_003961583.1|2500059_2501640_-|methylmalonyl-CoA-mutase	gnl|CDD|239652	cd03680, MM_CoA_mutase_ICM_like, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM from S. cinnamonensis is comprised of a large and a small subunit. The holoenzyme appears to be an alpha2beta2 heterotetramer with up to 2 molecules of coenzyme B12 bound. The small subunit binds coenzyme B12. ICM catalyzes the reversible rearrangement of n-butyryl-CoA to isobutyryl-CoA, intermediates in fatty acid and valine catabolism, which in S. cinnamonensis can be converted to methylmalonyl-CoA and used in polyketide synthesis.	0
NZ_CP016559.1|WP_003958922.1|2499310_2499970_-|leucine-efflux-protein-LeuE	gnl|CDD|236807	PRK10958, PRK10958, leucine export protein LeuE; Provisional.	5.94644e-102
NZ_CP016559.1|WP_003958942.1|2510586_2512341_+|succinate-dehydrogenase-flavoprotein-subunit	gnl|CDD|236185	PRK08205, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
NZ_CP016559.1|WP_003958917.1|2493966_2494950_+|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.51557e-34
NZ_CP016559.1|WP_009997366.1|2501835_2502816_+|L,D-transpeptidase-family-protein	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	3.11677e-22
NZ_CP016559.1|WP_003958921.1|2498876_2499182_-|DUF1876-domain-containing-protein	gnl|CDD|378103	pfam08962, DUF1876, Domain of unknown function (DUF1876). This domain is found in a set of hypothetical bacterial proteins.	3.21161e-28
NZ_CP016559.1|WP_003958919.1|2497502_2498135_+|CBS-domain-containing-protein	gnl|CDD|341362	cd04586, CBS_pair_BON_assoc, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection proteins. It is also found in some secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	5.92504e-39
NZ_CP016559.1|WP_003961580.1|2503640_2505179_-|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.13002e-08
NZ_CP016559.1|WP_003958944.1|2513275_2513848_+|hypothetical-protein	gnl|CDD|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	0.00336766

Protein sequences

>NZ_CP016559.1|WP_009997366.1|2501835_2502816_+|L,D-transpeptidase-family-protein
MSGAGVRRSVAALAVLTAVTGCTAEAADRPASAHGDGDTGGGAPTAERVPGPRKSTDTAHSPAVRPERRAADAQRTRTTPKEQQAQKARTQRAPERPARSTDTIPAAGQATVVMSRGAQGPRVRELQARLAQIGWFGSAPTGFYGRLTADAVRGFQGKRGLSVTGLTDTTTWRKLRGMTTAPTAEELSGTRKDPVKAAHKPRPRLDPRCLNGRVLCISKTTRSLSWVVDGTVRSTMDVRFGAEYTPTREGVFSVFWKSRHHVSTLYDTPMPYAMFFSGGQAVHYSADFAAQGYNGASHGCVNVRNRSAVAALFAEVRTGDKVVVHW
>NZ_CP016559.1|WP_003961583.1|2500059_2501640_-|methylmalonyl-CoA-mutase
MTRRSESGQPIEPVYDQNALTDWDPAGKLGAPGAYPFTRGVYPTMYTGRPWTMRQYAGFGTAAESNARYRRLIEHGTTGLSVAFDLPTQMGHDSDAPLAHGEVGRVGVAIDSIEDMRVLFDGIPLDRVSTSMTINAPAAPLLLLHQLVAEEQGAAPARLTGTVQNDILKEYIARGTYIFPPRPSLRLVADIFRYCRTELPQWNTISISGYHMAEAGATPAQEIAFTLANGVEYVRTALAAGMRVDEFAPRLSFFFVARTTLLEEIAKFRAARRIWARLMREEFGAREPRSLMLRFHTQTAGVQLTAQQPEVNLVRVALQGLGAVLGGTQSLHTNAFDEAIALPTERAARLALRTQQVLAYETDVTATVDPFAGSYAMESLTDGIEGAVLALMERIEERGGAVRAIEEGFQKGEIERSAYRIARETESGERVVVGVNRFTVDEEEPYEPLRVDPGIEARQTERLAALRAGRDGAAVAGALGELRAAARGTANVLPPMKEALRARATVGEVCGALREEWGEYVPDERL
>NZ_CP016559.1|WP_003958922.1|2499310_2499970_-|leucine-efflux-protein-LeuE
MLGVTDLPTYLAGLVLIILLPGPNSLYVLSVAARRGVRQGYTAAAGVFLGDTVLMVLAAAGAASLLQTNALLFGAVKLLGAGYLTWMAIGMLRAAWAMWRTRREQGSDTGSAAGAESGPGERPFRRALVISLLNPKAILFLLAFFVQFVDPAYPYPALSFLLLGGCLQLGSFLYLSGLIFTGTRLADAFRRRRALSAGATSAAGALFLGFAVKLSLSSA
>NZ_CP016559.1|WP_003958921.1|2498876_2499182_-|DUF1876-domain-containing-protein
MATRIREWTVGLQLVEEDGTTTARAVLDTGTATLTGRGAAHCNPQDVDIPQIGEELAAGRAMRDLSGRLMRAADHDLEAVGAGPAPRPVQTPLFGWPPESC
>NZ_CP016559.1|WP_003958919.1|2497502_2498135_+|CBS-domain-containing-protein
MRHRRVADLMTPVAVSVQRGTAFKEIARLLDEYGITAVPVVDEDERPVGVVSEADLLRRQTSRTTAGTAEGLMTSPAIVAEPEWSVVRAARVMEEKRIKRLPVVDGEGRLTGVVSRSDLLRLFLRRDRAIQEEILEDVLTQTLGLPPSALTVDVTDGRVTLSGTVERRGVRPVFVRLCESVEGVVEVVDRLVYPEDDPQEGAPEGVRGDA
>NZ_CP016559.1|WP_003958918.1|2496485_2497151_-|XRE-family-transcriptional-regulator
MNTRRSTATALSALALVTGLVTGLGTGMAAAGDQEPATVSVPLRPLTADDSGKREKDRGEADLLQPRRAETRRAVRGATGADDRGRAAATDDTGSTDDTGSTEAADSTDSAASTDSAEAATADDRTAARARAGAQARCSVTGSHPNRTAGYSSTSTQIVREGARGNVVREIQCLLDYWGIFPHAIDGVFGPLTKDAVVEAQRRCQIAQDGIVGPNTWYCIR
>NZ_CP016559.1|WP_003961584.1|2494946_2496413_+|hypothetical-protein
MTTTPTTQSASAPRSVRTTQICYASSLYGIATLAAAIDSGAFGPADRRLLLVANNATTPETSPAPTDMPGFERLRDRFDGVLSWNEAVAPFHPGGWSPRVDDRPLWHRYLRLLWGLGDDRVELAVESLQVTPALTIAHLFPDAPLDVYADGLMSYGPTRNRIDPLVGERVRRVLHPDLVPGLGPLLLEEFGAAAEVVPSDALVRVFGELADAEPDGTAERTETAETAETAETAETVPGPESATGPAGGPGAGGGAGGALLLGQYLAALGILTPEEEEGLHLRMVRGAVARGHRKLVFKPHPTAPAAWTRALEREAAALGAELAVLDRPVLAEVVFLRLRPALVVGCFSTALLTASAFFGLPVARVGTGPLLDRLTPYENSNRIPLTIVDAVVPELTEDGGTGAEPPYGDLPGLVAAVGFAMQARLRPDLRERAERFLAERAGDGRTARYFKRRRLTALGLPGGVPVPRNAAVREVVRRARRLKRAALR
>NZ_CP016559.1|WP_003958917.1|2493966_2494950_+|glycosyltransferase-family-2-protein
MVKLSVIVPFYNVRTYAPDTLRSLRLNARDDFEFLLVDDCSTDETPEILEKAEREIPGARLIRHRENGGLATARNTGLAAARGEHLTFLDGDDWLAPGHFAHLLSALEELGCDFVRTDHVQCTGRGRTVRRVPVGRRGVVLDPREAILPADRPTAVDYPYAWAGMYHRRLLERGLLHFTDGLRTAEDRPWIWRLHRDADSFAVISRLGIFYRRGIPSSLTQIGDVRQLDFLRAFDQILAETAADRDSALLLPKAVRTYCAVIAHHMGSIGKFEPEVARKLRTLSGAALRRMPQDVLDDVLGAMDSERATRLRRLRRRHPLTGGEAAA
>NZ_CP016559.1|WP_003961586.1|2492472_2493789_-|hypothetical-protein
MPSPISGAPRVAVLADSDTRWKWGALTARRLVPGPARPTGYLLRGRATPTPRQLAEVGAEASALHEVTGTEFLRTVADGGCDVVVLALVGGGVQAMLHGLAALPPARRPVVVTGYVGVVYEKLADGLLLRHGADLVLANSRQDARRFREVYEGVGADPSAVVEAALPFLGGAPYRPEEGRDTLVFAAQPSVPASRAERAYVLRRLIGHARLHPGREVLLKLRSRPGEHTTHLEEFPYQRLAGQATGPLPPNLRLVHGHMGEVLDRTDLLVTVSSTAALESLHRSIPTAVLTDLGVREPHGNHHFIGSGLLTSFDALDSGHRPVPDPHWLGEQGVATGGGYETAFDAARGRLAALLDGGPLPPIRPYYTPATAPGYLPGILARHRLAPDGTPLAGAEPGPGAAGGVRRLVRDAVRGAARGAYRQGVQRVAPAIRRMGEL
>NZ_CP016559.1|WP_003961587.1|2490895_2492236_-|acylneuraminate-cytidylyltransferase
MTVLAVIPARGGSKGVPGKNLAPVGGVPLVVRAVREALAAPLVTDVAVSTDDPGIAAAARAAGAWVVDRPAGLSGDTASSEAAVLHALDAFGAAHGARVRAVLLVQCTSPFLTREDIQGVAAAVVRDGADSAVTVAPFHGFVWREGADPGPDTDPGPGKDTGPGPGLGTASSGVGVNHDAAVRPRRQDRPRDHLETGAAYAMDAEGFRAARHRFFGRTALVRTDPARVLEIDDPHDLARARALAPLLDTAARGTALPTRADIDAVVLDFDGTQTDDRAWIDAEGRETVAVHRGDGLGVARLREAGLDLLILSTERNPVVAARALKLRIPVLQGIDRKDLALSRWCEERGIDLRRVLYAGNDVNDLPCFSLAGWPVAVADAHGPVRAAARAVTAAPGGHGAVREIASWLLGPALTPTPDSPPDSAPCSPPCSADGPAELLSAAPPTR
>NZ_CP016559.1|WP_003961580.1|2503640_2505179_-|hypothetical-protein
MADDGHDWLDEDTAERLLRGEAFDGPGGSGGPVGTGRAGAHRLNEALSGVRRARDAIPAGDGGELPGEEAALTAFRAARAEGAGGTAPAARAAGETGTSLGVVRLDRAGRPARRRRLARPARSGVIALVAGFAFSGVAVATGTGLLPSPFKETQAGATVRGAGVPEPLGTQVPKGPGTADPGQRSPRGPSFADDEASDGPGAEAGADGGTGGAPEDGTGAPRHGGGPEEARGLGEGRYGDGHHSGERHPRLREACRDHRDGSLKGKRSERLSRIAGGPDRVDDFCDTVLRDREPEPEREREPEREREREREDEGKRGNAGKGGDRRPGNQGGNGQGQSHQGGQGNRGNQGSQNGQGQGWGAGRPDRGPGGSGSAGGSSRPEQPRPDRPQKGRPGQGSSGNPGQQGQGQGQSGKARGHGVDGQDGAADRDPSHRVPGSGAPGVAADGNRVEPTGAATTASGGGTADAAHERQQPGAAPPRPARVPRPDPGPVADAASAEGAGGVARAGSGTGG
>NZ_CP016559.1|WP_009997365.1|2505178_2505991_-|RNA-polymerase-sigma-factor
MLGDDAELTAAVLAAQHGDESAFRTVYRAVHPRLLGYVRTLVGEPDAEDVTSEAWLQIARDLDGFSGDADRFRGWTARIARNRALDHIRMRGRRPAVGGDETELTGRPAPSDTADEAMEALATGSTMALIARLPQDQAEAVVLRVVVGLDAKSAARTLGKRPGAVRTAAHRGLKKLAELLDAEPPGARGGGEPPVGHGARDRPEYADPAGRAYGADGVGGSDGRRSARVPDAPHDCGADLNGMPPQRVSRPGAGAPAGVTRTGLRTQKDM
>NZ_CP016559.1|WP_009997364.1|2506499_2507099_-|hypothetical-protein
MTSKCLRELIAEADERSLAASGLACLERCLPLSAADVDALRPLWAGLARGAAAWPVSLASASEALAVAAVREPAALDPAASLVRQMLDAAPSVWETEPLREWADDCSVAALELHHRFDAGPGRGEPAAADVVEVLKGCREGAPAGAGPLVAGELRRQVRVLEILAAGEGGAGLRQVLGVSTEGRRVLRAVVSRQARVRG
>NZ_CP016559.1|WP_003961577.1|2507472_2509146_-|family-20-glycosylhydrolase
MIRHGGRIRSAAGTAVALTAVLSLTLSGCGDGAADGSGESSGTGGVDRASVGSAERSATPGPASPSPSRVYPLSKPPATIPAVRSHTAARGPGWRPAPGAGVALAPGSEELADEARLLARELKLDYRGTAAARGGDVELVLDPDAATGPAPAAPAGAVGPESYTLTTADNRVRVVAPAEAGVFYGTRTLKQAVRSGGAMPEGVVRDGPDRPQRGLMVDTARKFFDGAWIEARLREAADLKINQFGLHFSDDQGFRIESDTHPGIVSRQHLTKAEVRRIVALADSLHITVIPEIDSPGHLGAVLAKYPGLQLKDVTGRAVPGAVDIGNPAAGELVDELLREYAELFPGAYWHLGGDEYQALTRRDPEASFPALAARAREEYGPDGRIKDLATAWVNERAKALRPGGRTLKAWNDGYFRGGETAVDQDIQVEYWTGKEIGARPPVEYLAEGRPVVNLNDEYLYYVLGEPNDFDYPTGRRIYEQWTPLVLRGTEPVPARYSRQILGGRFAVWCDFSRAQTPEQIARGIALPLRATAQKLWDPRTPSRSWQEFRTLAQRLG
>NZ_CP016559.1|WP_003958940.1|2509695_2510076_+|succinate-dehydrogenase,-cytochrome-b556-subunit
MPAGTLYRGREGMWSWVAHRVTGVLIFFFLFVHVLDTALVRVSPEDYDKVVAVYKTPIVALLEYGLVAAVLFHALNGLRVIAVDFWSKGPRYQKQMLWTVMGIWIVLMAGALYPVLGHAAREVFGS
>NZ_CP016559.1|WP_003958941.1|2510084_2510561_+|succinate-dehydrogenase-hydrophobic-membrane-anchor-subunit
MSADTSSAIGSVESAPVYDVDNPAPVIEAPRKRTGRTPRSTRGNFEMAAWLFMRLSGVVLVVLVIGHLIIQLVLDGGVSKIGFAFVAGRWASPFWQVWDLLMLWLAMLHGANGLRTVINDYAERPNTRLWLKGLLYTATVFTILLGTLVIFTFDPNIR
>NZ_CP016559.1|WP_003958942.1|2510586_2512341_+|succinate-dehydrogenase-flavoprotein-subunit
MKIHKYDTVIVGAGGAGMRAAIEATKRSRTAVLTKLYPTRSHTGAAQGGMAAALANVEEDNWEWHTFDTVKGGDYLVDQDAAEILAKEAIDAVLDLEKMGLPFNRTPNGTIDQRRFGGHSRNHGEAPVRRSCYAADRTGHMILQTLYQNCVKEGVEFFNEFYVLDQLITEVDGVKHSAGVVAYELATGEIHVFQAKAVIYASGGTGKFFKVTSNAHTLTGDGQAACYRRGLPLEDMEFFQFHPTGIWRMGILLTEGARGEGGILRNKDGERFMEKYAPVMKDLASRDVVSRSIYTEIREGRGCGPEGDHVYLDLTHLPPEQLDAKLPDITEFARTYLGIEPYTDPIPIQPTAHYAMGGIPTNVEGEVLSDNTTVVPGLYAAGEVACVSVHGANRLGTNSLLDINVFGRRAGIAAAEYSATAEWVELPEDPASLVVKTVEDLRESEGGERVADIRRELQETMDANVMVFRTEQTIKTAVEKIAELRERYRNVAIQDKGKRFNTDLLEAIELGNLLELAEVMAVSALARKESRGGHYREDYPNRDDVNFMRHTMAYREVGDDGSETVRLDYKPVVQTRYQPMERKY
>NZ_CP016559.1|WP_003958943.1|2512340_2513099_+|succinate-dehydrogenase-iron-sulfur-subunit
MATPVMDKVEAEAAASPYITVTFRIRRFNPEISEHAVWEDFELEIDPKERVLDGLHKIKWDQDGTLTFRRSCAHGICGSDAMRINGKNRLACKTLIKDLNPEKPITVEAIKGLTVLKDLVVDMEPFFQAYRDVMPFLVTEGNEPTRERLQTAEDRERFDDTTKCILCAACTTSCPVFWNDGQYFGPAAIVNAHRFIFDSRDEAGEQRLEILNDKDGVWRCRTTFNCTDACPRGIEVTKAIQEVKRALITRRY
>NZ_CP016559.1|WP_003958944.1|2513275_2513848_+|hypothetical-protein
MNEPNPYQAEGEPEYQWGPPQPYGYPQQGPGYGDPHAGPPAHPGYAPTQPGYTPTQPAGTPVPGAVAGYGPAPLAPMSPAVTIGDITVVGDQIITPAGTMPLKGAVWNAVDLSRTSEKIPTYAIVLAVVFSLACLVGLFFLLMKEKETSGYIQVSVASGGKHHTTMIPAHGPEVFQQVMAQVGYARTLSV
>NZ_CP016559.1|WP_003961576.1|2513914_2515420_-|membrane-protein
MLAVVVLVVIAVVALLAGVHWYVWRRVVRDTTRGPGTARRVGTVALVILPVLSVGALVARRAGVPFWLERILAWPGYLWLAVLLYLVLALLVGEAVRAIWLRWDRTAKRTARSGRPETTATAAPVTSTTTSTITGTTTSTTTSSATGADAGTAPVAARPEPVPVPGAEEPRETAARQDTDAGTASASGTSSGTAKPEPAPESEPASEPVTEIAPAPGPAAAEPARAVSRRLFVSRTVAAGAAAAALGTVGHGAHGVLRGPRLKRVTVPLAKLPRSAHGLRIAVVSDIHIGPILGRAHTQRIVDTINAAQPDLVAVVGDMVDGTVADLGPAAEPLAQLRARHGSFFVTGNHEYFSGAEQWVEHVRELGLKPLENERVEIAGGFDLAGVNDVEGESTGQGPDFARALGDRDRSRAAVLLAHQPVVIHDAVEHGVDLQLSGHTHGGQLWPGNYLAELANPTVAGLERYGDTQLYVSRGAGAWGPPVRVGAESDITIVQLASRQA

Crispr_ID: NZ_CP016559_7

• CRISPR_ID: NZ_CP016559_7
• CRISPR_location: 2635712-2635859
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_7

Consensus_repeat	Method
CCTCGGCCGTGCGTCAGACGCGGCGGCGCTTCGGCGGACGGCAGCCGT	CRISPRCasFinder

spacers of NZ_CP016559_7

>7.1|2635760|52|NZ_CP016559|CRISPRCasFinder
ACTGCGACATGAGGGGGATGACCCCCACACCCCCAGCAGGCTGCCGACCGTG

CRISPR arrays and Neighbor proteins around NZ_CP016559_7

CRISPR arrays

The CRISPR arrays of NZ_CP016559_7

>merge|NZ_CP016559|7|2635712-2635859|CRISPRCasFinder
CCTCGGCCGTGCGTCAGACGCGGCGGCGCTTCGGCGGACGGCAGCCGTACTGCGACATGAGGGGGATGACCCCCACACCCCCAGCAGGCTGCCGACCGTGCCTCGGCCGTGCGTCAGACGCGGCGGCGCTTCGGCGGACGGCAGCCGT

>NZ_CP016559|7|6|2635712-2635859|CRISPRCasFinder
CCTCGGCCGTGCGTCAGACGCGGCGGCGCTTCGGCGGACGGCAGCCGT	ACTGCGACATGAGGGGGATGACCCCCACACCCCCAGCAGGCTGCCGACCGTG
CCTCGGCCGTGCGTCAGACGCGGCGGCGCTTCGGCGGACGGCAGCCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003956426.1|2630117_2631740_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NZ_CP016559.1|WP_003961513.1|2632876_2633743_-|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl|CDD|234577
NZ_CP016559.1|WP_003956430.1|2634553_2635576_-|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl|CDD|235359
NZ_CP016559.1|WP_003956424.1|2629383_2629827_-|50S-ribosomal-protein-L13	unknown	unknown	gnl|CDD|181703
NZ_CP016559.1|WP_003956420.1|2625325_2626072_-|glucosamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl|CDD|234729
NZ_CP016559.1|WP_003956445.1|2639271_2640591_-|preprotein-translocase-subunit-SecY	unknown	unknown	gnl|CDD|236412
NZ_CP016559.1|WP_003956422.1|2627275_2628634_-|phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|237672
NZ_CP016559.1|WP_003961515.1|2626144_2627185_+|type-I-pantothenate-kinase	unknown	unknown	gnl|CDD|235466
NZ_CP016559.1|WP_003956433.1|2636327_2636708_-|30S-ribosomal-protein-S13	unknown	unknown	gnl|CDD|235358
NZ_CP016559.1|WP_003956429.1|2633879_2634386_-|50S-ribosomal-protein-L17	unknown	unknown	gnl|CDD|235522
NZ_CP016559.1|WP_003956443.1|2637557_2638394_-|type-I-methionyl-aminopeptidase	unknown	unknown	gnl|CDD|235576
NZ_CP016559.1|WP_003956447.1|2641305_2641488_-|50S-ribosomal-protein-L30	unknown	unknown	gnl|CDD|180163
NZ_CP016559.1|WP_003956441.1|2636922_2637036_-|50S-ribosomal-protein-L36	unknown	unknown	gnl|CDD|179039
NZ_CP016559.1|WP_003956446.1|2640848_2641304_-|50S-ribosomal-protein-L15	unknown	unknown	gnl|CDD|235523
NZ_CP016559.1|WP_003956444.1|2638627_2639272_-|adenylate-kinase	unknown	unknown	gnl|CDD|234711
NZ_CP016559.1|WP_003956449.1|2642159_2642543_-|50S-ribosomal-protein-L18	unknown	unknown	gnl|CDD|235524
NZ_CP016559.1|WP_009997308.1|2631796_2632903_+|hypothetical-protein	unknown	unknown	gnl|CDD|236669
NZ_CP016559.1|WP_003956423.1|2628823_2629342_-|30S-ribosomal-protein-S9	unknown	unknown	gnl|CDD|178888
NZ_CP016559.1|WP_003956442.1|2637090_2637312_-|translation-initiation-factor-IF-1	unknown	unknown	gnl|CDD|178954
NZ_CP016559.1|WP_003956448.1|2641487_2642093_-|30S-ribosomal-protein-S5	unknown	unknown	gnl|CDD|234790

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003956426.1|2630117_2631740_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	7.03815e-94
NZ_CP016559.1|WP_003961513.1|2632876_2633743_-|tRNA-pseudouridine(38-40)-synthase-TruA	gnl|CDD|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	2.3273e-107
NZ_CP016559.1|WP_003956430.1|2634553_2635576_-|DNA-directed-RNA-polymerase-subunit-alpha	gnl|CDD|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
NZ_CP016559.1|WP_003956424.1|2629383_2629827_-|50S-ribosomal-protein-L13	gnl|CDD|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	6.09729e-102
NZ_CP016559.1|WP_003956420.1|2625325_2626072_-|glucosamine--fructose-6-phosphate-aminotransferase	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	1.99401e-93
NZ_CP016559.1|WP_003956445.1|2639271_2640591_-|preprotein-translocase-subunit-SecY	gnl|CDD|236412	PRK09204, secY, preprotein translocase subunit SecY; Reviewed.	0
NZ_CP016559.1|WP_003956422.1|2627275_2628634_-|phosphoglucosamine-mutase	gnl|CDD|237672	PRK14318, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP016559.1|WP_003961515.1|2626144_2627185_+|type-I-pantothenate-kinase	gnl|CDD|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	0
NZ_CP016559.1|WP_003956433.1|2636327_2636708_-|30S-ribosomal-protein-S13	gnl|CDD|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	3.42536e-76
NZ_CP016559.1|WP_003956429.1|2633879_2634386_-|50S-ribosomal-protein-L17	gnl|CDD|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	5.44515e-61
NZ_CP016559.1|WP_003956443.1|2637557_2638394_-|type-I-methionyl-aminopeptidase	gnl|CDD|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	7.64897e-120
NZ_CP016559.1|WP_003956447.1|2641305_2641488_-|50S-ribosomal-protein-L30	gnl|CDD|180163	PRK05611, rpmD, 50S ribosomal protein L30; Reviewed.	2.47973e-26
NZ_CP016559.1|WP_003956441.1|2636922_2637036_-|50S-ribosomal-protein-L36	gnl|CDD|179039	PRK00465, rpmJ, 50S ribosomal protein L36; Reviewed.	3.28149e-12
NZ_CP016559.1|WP_003956446.1|2640848_2641304_-|50S-ribosomal-protein-L15	gnl|CDD|235523	PRK05592, rplO, 50S ribosomal protein L15; Reviewed.	9.91371e-69
NZ_CP016559.1|WP_003956444.1|2638627_2639272_-|adenylate-kinase	gnl|CDD|234711	PRK00279, adk, adenylate kinase; Reviewed.	6.65522e-133
NZ_CP016559.1|WP_003956449.1|2642159_2642543_-|50S-ribosomal-protein-L18	gnl|CDD|235524	PRK05593, rplR, 50S ribosomal protein L18; Reviewed.	1.28557e-55
NZ_CP016559.1|WP_009997308.1|2631796_2632903_+|hypothetical-protein	gnl|CDD|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	2.10283e-05
NZ_CP016559.1|WP_003956423.1|2628823_2629342_-|30S-ribosomal-protein-S9	gnl|CDD|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.48128e-73
NZ_CP016559.1|WP_003956442.1|2637090_2637312_-|translation-initiation-factor-IF-1	gnl|CDD|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	7.62048e-47
NZ_CP016559.1|WP_003956448.1|2641487_2642093_-|30S-ribosomal-protein-S5	gnl|CDD|234790	PRK00550, rpsE, 30S ribosomal protein S5; Validated.	2.03132e-92

Protein sequences

>NZ_CP016559.1|WP_003956430.1|2634553_2635576_-|DNA-directed-RNA-polymerase-subunit-alpha
MLIAQRPSLTEEVVDEYRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTDLILNIKQLVVSSEHDEPVVMYLRKQGPGLVTAADIAPPAGVEVHNPDLVLATLNGKGKLEMELTVERGRGYVSAVQNKQVGQEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIVDVETKQAMRPRDAMASAGKTLVELFGLARELNIDAEGIDMGPSPTDAALAADLALPIEELELTVRSYNCLKREGIHSVGELVARSEADLLDIRNFGAKSIDEVKAKLAGMGLALKDSPPGFDPTAAADAFGADDDADAGFVETEQY
>NZ_CP016559.1|WP_003956429.1|2633879_2634386_-|50S-ribosomal-protein-L17
MPKPAKGARLGGSAAHERLLLANLAKALFEHGRITTTEAKARRLRPVAERLITKAKKGDIHNRRLVLQTITDKGIVHALFTEIAPRYAERPGGYTRITKIGNRRGDNAPMAVIELVEGEIAKKATVAEAEAATQRAVKEDALKKEEAATEDAPAAEAADEAKAESKDA
>NZ_CP016559.1|WP_003961513.1|2632876_2633743_-|tRNA-pseudouridine(38-40)-synthase-TruA
MSDEVEPGSVRVRLDLSYDGRDFSGWARQAGGRRTVQGEIEDALRTVTRSARPYELTVAGRTDAGVHARGQVAHVDLPAEVWAEHREKLLKRLAGRLDRDVRIWRAEEAPAGFNARFSAVWRRYAYRVSDHPGGVDPLLRGHVLWHDWPLDVAAMNAASQPLLGEHDFAAYCKKREGATTIRTLQRLSWERDAAGVITATVRADAFCHNMVRSLVGALLFVGDGHRPVDWPGKVLAAGVRDSAVHVVRPHGLTLEEVGYPADELLAARNREARNKRSLPGSAGGAGCC
>NZ_CP016559.1|WP_009997308.1|2631796_2632903_+|hypothetical-protein
MSFGQGGPSHGSDGQGGDPYGSGQHNPYSGGRQGEERQGPYGGQQGAPGPYQGQPNQPNPYGPGAGQPNPYGQPQPYPGYPQQGGPGQPQPPQQQPRPQAAQQPPAASTTPDWAALADASAARDRRKRRTLIGGAAVAAVAVAATAAGVLLTSGDDGTKDNRGGQSARPSTSGGTSPGPTGAPKPPPTAQEIVADEKLDTAPLTVDTLFPGRRMTAGDRAYTKSTVARADACSAVTQGGLGDVLERNGCDQVFRATYTRGKISVTVGVAVFGLEREAKKAIEQSKGNIAPLKAKGGPDFCKGGPVCRFTANSYGRYAYFTTTGLTGGKPVKKGDEAAFKAGDDVAETVFRGLVGRGETKASAAAGATG
>NZ_CP016559.1|WP_003956426.1|2630117_2631740_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGHLEAAHLEYYLPDGRVLLADVSFRVGEGAVVALVGANGAGKTTLLRLLSGELKAHGGTVTVSGGLGVMPQFIGSVRDERTVRDLLVSLAQPRVREAARAVDEAEHLIMTVDDEAAQMRYAQALSDWAEARGYEAETLWDMCTTAALGVPYERAQWRELRTLSGGEQKRLALEALLRGPDQVLLLDEPDNYLDVPGKRWLEERLKETRKTVLFVSHDRELLSRAAQKIVSVEPGPAGSDVWVHGGGFATYHEARQQRFARFEELKRRWDEKHAQLKALVHRLRQQAAISPDMASRYAAAQTRLRKFEEAGPPPEPPREQEIRMRLRGGRTGVRAVTCAGLELTGLMKPFDLEVFYGERVAVLGSNGSGKSHFLRLLAGDASVAATGAWKLGARVVPGHFAQTHAHPELEGRTLVDILWTEHAKDRGGAMSVLRRYELERQGDQSFDRLSGGQQARFQILLLELVGTTALLLDEPTDNLDLESAEALQDGLESYEGTVLAVTHDRWFARSFDRYLVFGSDGVVRETREPVWDERRVQRAR
>NZ_CP016559.1|WP_003956424.1|2629383_2629827_-|50S-ribosomal-protein-L13
MRTYSPKPGDVTRQWHVIDAQDVVLGRLATTAATLLRGKHKPIYAPHVDAGDFVIIINADKVHLSGNKRTQKMAYRHSGYPGGLRSVRYDELMDKNPEKAVEKAVKGMLPKNSLGRQMLSKLKVYAGENHPHAAQQPVPFEITQVAQ
>NZ_CP016559.1|WP_003956423.1|2628823_2629342_-|30S-ribosomal-protein-S9
MAETTAEIPVEGEETYAEVTTFESEVPVEGEYTSESLASRFGDPQPAAGLGRRKNAIARVRIVPGTGKWKINGRTLEDYFPNKVHQQEVNEPFKVLELDNRYDVVARISGGGVSGQAGALRLGVARALNEADVDNNRGPLKKAGFLSRDDRAVERKKAGLKKARKAPQYSKR
>NZ_CP016559.1|WP_003956422.1|2627275_2628634_-|phosphoglucosamine-mutase
MGRLFGTDGVRGVANADLTAELALGLSVAAAHVLAEAGTFEGHRPTAVVGRDPRASGEFLEAAVVAGLASAGVDVLRVGVLPTPAVAYLTGALGADLGVMLSASHNAMPDNGIKFLARGGHKLADELENRIESVYEQHRSGEPWNRPTGVGVGRVRDYDEGFDKYIAHLVAVLPNRLDGLRIVLDEAHGAAARVSPEAFARAGAEVVTIGAEPDGLNINDGCGSTHLGLLKAAVVAHGADFGIAHDGDADRCLAVDGAGEEVDGDQIMAVLALALRDAGALRGNTVVGTVMSNLGFKLAMEREGVQVVQTAVGDRYVLESMKEHGYALGGEQSGHVIVLDHATTGDGTLTGLLLAARVAATGRSLAELAAVMERLPQVLINVPDVDRSRVHTSGELAAAVADAERELGTSGRVLLRPSGTEPLVRVMVEAADSEQARSVAERLADVVKSALG
>NZ_CP016559.1|WP_003961515.1|2626144_2627185_+|type-I-pantothenate-kinase
MEVISSPPPFPSANVPPTASAGGPRRGGEPAPTPFVDLTRAQWSALRDRTPLPLTADEVERLRGLGDVIDLDEVRDVYLPLSRLLNLYVQATGELRGALNTFLGDAGRGQGEQRGTPFVIGVAGSVAVGKSTVARLLQALLARWPEHPRVERVTTDGFLYPMKELRARGLMSRKGFPESYDRRALTRFVADVKSGKEEVTAPVYSHLIYDIVPGERLVVRRPDILIVEGLNVLQPAQPGQDGRTRVGLADYFDFSVYVDARPEDIESWYLHRFRRLRETAFQDPSSYFRKYTQVSEEESMEYARTMWRTVNQPNLLENVAPTRGRATLILRKGADHKVRRLSLRKL
>NZ_CP016559.1|WP_003956420.1|2625325_2626072_-|glucosamine--fructose-6-phosphate-aminotransferase
MCAIVGYTGGRSALEVLWEGLERLTDREYDAAGVAVVSDGGLATAKKAGPLERLERELTRRPLPSGSTGVGHIRRGTGESGGDADAHPHLDNAGRVAVVHNGVIGNHAALRAELTRRGHALVSATDTEVVAHLLAESFSSCGDLAEAMRQVYGRLDGVFALAAVGADDPDVLVGAVRGLPLLVGVGDGESFLASDAAALAGVARSVVEPGDGRVVEVRRDGVSVTDADGAVVEVLPYRAAGVPAAGAP
>NZ_CP016559.1|WP_003956433.1|2636327_2636708_-|30S-ribosomal-protein-S13
MARVSGVDIPREKRVEIALTYVFGIGRTLAQETLAATGVNPNTRVRDLAEEDLVKIREYVDNNIKTEGDLRREIQADIRRKVEIGCYQGLRHRRGLPVHGQRTSTNARTRKGPRRAIAGKKKPGKK
>NZ_CP016559.1|WP_003956441.1|2636922_2637036_-|50S-ribosomal-protein-L36
MKVKPSVKKICDKCKVIRRHGRVMVICDNLRHKQRQG
>NZ_CP016559.1|WP_003956442.1|2637090_2637312_-|translation-initiation-factor-IF-1
MAKKQGAIEIEGTVIESLPNAMFKVELQNGHKVLAHISGKMRMHYIRILPDDRVVVELSPYDLTRGRIVYRYK
>NZ_CP016559.1|WP_003956443.1|2637557_2638394_-|type-I-methionyl-aminopeptidase
MVQIKTPEQIAKMREAGLVVAAIHAATREAAVPGATTRDLDEVARKVIAEHGAKSNFLGYGGFPATICTSVNEVVVHGIPDDKTVLKDGDIISIDAGAVIDGWHGDAAYTAFVGTGHAPELVELSRVTEASMWAGIAAMKSGNRLVDVSRSIETYIRRQPKPGGGRYGIIEEYGGHGIGTEMHMEPHLLNYVARKRGKGPKLVPGLCLAIEPMVSLGTPKTEVLADEWTVITTDGTWSSHWEHSVAVTEEGPLVLTAPDCGRARLAELGITAAPDPLG
>NZ_CP016559.1|WP_003956444.1|2638627_2639272_-|adenylate-kinase
MRIVLVGPPGAGKGTQAAYLAENLSIPHISTGDLFRANISQGTDLGRQAKSYMDAGELVPDEVTIGMAKDRMERPDATGGFLLDGFPRNVSQAEALDAMLKSEGMTLDAVLDLEVPEDEVVKRIAGRRICRNDSSHVFHVTYSPPAQEGVCDVCGGDLYQRDDDSETTVRKRLEVYHTQTEPIIDYYRGQGLVVTISALGKVTEVTQRAMAALQ
>NZ_CP016559.1|WP_003956445.1|2639271_2640591_-|preprotein-translocase-subunit-SecY
MLTAFARAFKTPDLRKKLLFTLAIIVLYRLGSHIPTPGIDYQNVQICVDQAQENNNSLFGLVNMFSGGALLQITIFALGIMPYITASIILQLLTVVIPRLEALKKEGQSGTAKITQYTRYLTIALAVLQGTGLVATARSGALFSGCQVANQIVPDQSIFTTVTMVITMTAGTAAVMWLGELITDRGIGNGMSILMFISIAAGFPGQLWAIKESGKLAQGWIEFGTVIAVGFVMVGLVVFVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQFSSGTSEWKTWIEKYFVTGDHPYYITAYFILIVFFAFFYVAISFNPEEVADNMKKYGGFIPGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALAFFGGANQNFPFGGTSILIIVGVGLETVKQIESQLQQRNYEGFLR
>NZ_CP016559.1|WP_003956446.1|2640848_2641304_-|50S-ribosomal-protein-L15
MAENNPLRLHNLAPAPGAKTAKTRVGRGEASKGKTAGRGTKGTKARYQVPERFEGGQMPLHMRLPKLKGFNNPFRTEYQVVNLDKLAALYPQGGEVTVADLVAKGAVRKNHLVKVLGQGEISVALQVTVDAVSGSAKEKIAAAGGTVTELV
>NZ_CP016559.1|WP_003956447.1|2641305_2641488_-|50S-ribosomal-protein-L30
MPRLKITQTKSYIGSKQNHRDTLRSLGLKRLNDVVVKEDRPEFRGMVHTVRHLVTVEEVD
>NZ_CP016559.1|WP_003956448.1|2641487_2642093_-|30S-ribosomal-protein-S5
MAGPQRRGSGAGGGERRDRKGRDGGAAAAEKTAYVERVVAINRVAKVVKGGRRFSFTALVVVGDGDGTVGVGYGKAKEVPAAIAKGVEEAKKHFFKVPRIQGTIPHPIQGEKAAGVVLLKPATPGTGVIAGGPVRAVLECAGIHDILSKSLGSDNAINIVHATVEALKGLQRPEEIAARRGLPLEDVAPAALLRARAGAGA
>NZ_CP016559.1|WP_003956449.1|2642159_2642543_-|50S-ribosomal-protein-L18
MAYGVKIAKGDAYKRAAIKRRHIRIRKRVNGTAERPRLVVTRSNRHIVAQVIDDIAGHTLASASTLDSSIRGGEGDKSAHAKQVGALVAERAKAAGVEAVVFDRGGNQYAGRIAALADAAREAGLKF

Crispr_ID: NZ_CP016559_8

• CRISPR_ID: NZ_CP016559_8
• CRISPR_location: 2712337-2712429
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_8

Consensus_repeat	Method
CCCGGCCCCGAACTCCTTCTCCAG	CRISPRCasFinder

spacers of NZ_CP016559_8

>8.1|2712361|45|NZ_CP016559|CRISPRCasFinder
GTCCTTGCCCAGGTCCTTGCCCAGGTCCTCGACGGCCTGGCCCGT

CRISPR arrays and Neighbor proteins around NZ_CP016559_8

CRISPR arrays

The CRISPR arrays of NZ_CP016559_8

>merge|NZ_CP016559|8|2712337-2712429|CRISPRCasFinder
CCCGGCCCCGAACTCCTTCTCCAGGTCCTTGCCCAGGTCCTTGCCCAGGTCCTCGACGGCCTGGCCCGTCCCGGCCCCGAACTCCTTCTCCAG

>NZ_CP016559|8|7|2712337-2712429|CRISPRCasFinder
CCCGGCCCCGAACTCCTTCTCCAG	GTCCTTGCCCAGGTCCTTGCCCAGGTCCTCGACGGCCTGGCCCGT
CCCGGCCCCGAACTCCTTCTCCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003956211.1|2715222_2716233_-|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|223220
NZ_CP016559.1|WP_003956226.1|2702256_2703306_+|EamA-family-transporter-RarD	unknown	unknown	gnl|CDD|225510
NZ_CP016559.1|WP_003961477.1|2721592_2723164_-|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|235622
NZ_CP016559.1|WP_003956219.1|2707763_2708210_+|hypothetical-protein	unknown	unknown	gnl|CDD|380093
NZ_CP016559.1|WP_003956223.1|2704938_2706387_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP016559.1|WP_009997278.1|2709878_2710901_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224196
NZ_CP016559.1|WP_065757112.1|2710887_2711847_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP016559.1|WP_003956205.1|2725085_2725385_-|NADH-quinone-oxidoreductase-subunit-NuoK	unknown	unknown	gnl|CDD|180218
NZ_CP016559.1|WP_003956224.1|2704423_2704861_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003961482.1|2703528_2704350_+|hypothetical-protein	unknown	unknown	gnl|CDD|377524
NZ_CP016559.1|WP_003961476.1|2725381_2726299_-|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl|CDD|235844
NZ_CP016559.1|WP_003956217.1|2708692_2709664_+|M28-family-peptidase	unknown	unknown	gnl|CDD|349873
NZ_CP016559.1|WP_003956220.1|2707145_2707742_-|hypothetical-protein	unknown	unknown	gnl|CDD|378696
NZ_CP016559.1|WP_003961479.1|2713780_2714947_-|CHRD-domain-containing-protein	unknown	unknown	gnl|CDD|377837
NZ_CP016559.1|WP_003956206.1|2723169_2725074_-|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl|CDD|235836
NZ_CP016559.1|WP_003956208.1|2719946_2721596_-|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl|CDD|235603
NZ_CP016559.1|WP_003956222.1|2706502_2707045_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP016559.1|WP_003961478.1|2716472_2718527_+|CocE/NonD-family-hydrolase	unknown	unknown	gnl|CDD|225487
NZ_CP016559.1|WP_003961475.1|2726295_2726916_-|NADH-quinone-oxidoreductase-subunit-NuoI	unknown	unknown	gnl|CDD|235637
NZ_CP016559.1|WP_009997277.1|2718595_2719825_+|fumarylacetoacetase	unknown	unknown	gnl|CDD|215461

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003956211.1|2715222_2716233_-|polyprenyl-synthetase-family-protein	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	1.35819e-92
NZ_CP016559.1|WP_003956226.1|2702256_2703306_+|EamA-family-transporter-RarD	gnl|CDD|225510	COG2962, RarD, Predicted permeases [General function prediction only].	3.85696e-102
NZ_CP016559.1|WP_003961477.1|2721592_2723164_-|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	0
NZ_CP016559.1|WP_003956219.1|2707763_2708210_+|hypothetical-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	4.57811e-28
NZ_CP016559.1|WP_003956223.1|2704938_2706387_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.76951e-35
NZ_CP016559.1|WP_009997278.1|2709878_2710901_-|ABC-transporter-permease	gnl|CDD|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	4.1345e-14
NZ_CP016559.1|WP_065757112.1|2710887_2711847_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.14351e-97
NZ_CP016559.1|WP_003956205.1|2725085_2725385_-|NADH-quinone-oxidoreductase-subunit-NuoK	gnl|CDD|180218	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK.	6.56857e-44
NZ_CP016559.1|WP_003961482.1|2703528_2704350_+|hypothetical-protein	gnl|CDD|377524	pfam05552, TM_helix, Conserved TM helix. This alignment represents a conserved transmembrane helix as well as some flanking sequence. It is often found in association with pfam00924.	2.33055e-10
NZ_CP016559.1|WP_003961476.1|2725381_2726299_-|NADH-quinone-oxidoreductase-subunit-J	gnl|CDD|235844	PRK06638, PRK06638, NADH-quinone oxidoreductase subunit J.	1.40294e-76
NZ_CP016559.1|WP_003956217.1|2708692_2709664_+|M28-family-peptidase	gnl|CDD|349873	cd03876, M28_SGAP_like, M28 Zn-peptidase Streptomyces griseus aminopeptidase and similar proteins. Peptidase family M28; Streptomyces griseus Aminopeptidase (SGAP, Leucine aminopeptidase (LAP), aminopeptidase S, Mername-AA022 peptidase) subfamily. SGAP is a di-zinc exopeptidase with high preference towards large hydrophobic amino-terminal residues, with Leu being the most efficiently cleaved. It can accommodate all except Pro and Glu residues in the P1' position. It is a monomeric (30 kDa), calcium-activated and calcium-stabilized enzyme; its activation by calcium correlates with substrate specificity and it has thermal stability only in the presence of calcium. Although SGAP contains a calcium binding site, it is not conserved in many members of this subfamily. SGAP is present in the extracellular fluid of S. griseus cultures.	1.12433e-139
NZ_CP016559.1|WP_003956220.1|2707145_2707742_-|hypothetical-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	2.9485e-19
NZ_CP016559.1|WP_003961479.1|2713780_2714947_-|CHRD-domain-containing-protein	gnl|CDD|377837	pfam07452, CHRD, CHRD domain. CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..	5.30877e-20
NZ_CP016559.1|WP_003956206.1|2723169_2725074_-|NADH-quinone-oxidoreductase-subunit-L	gnl|CDD|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP016559.1|WP_003956208.1|2719946_2721596_-|NADH-quinone-oxidoreductase-subunit-NuoN	gnl|CDD|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	0
NZ_CP016559.1|WP_003956222.1|2706502_2707045_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.02621e-36
NZ_CP016559.1|WP_003961478.1|2716472_2718527_+|CocE/NonD-family-hydrolase	gnl|CDD|225487	COG2936, COG2936, Predicted acyl esterases [General function prediction only].	9.4745e-77
NZ_CP016559.1|WP_003961475.1|2726295_2726916_-|NADH-quinone-oxidoreductase-subunit-NuoI	gnl|CDD|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	2.9178e-79
NZ_CP016559.1|WP_009997277.1|2718595_2719825_+|fumarylacetoacetase	gnl|CDD|215461	PLN02856, PLN02856, fumarylacetoacetase.	7.76002e-147

Protein sequences

>NZ_CP016559.1|WP_065757112.1|2710887_2711847_-|ABC-transporter-ATP-binding-protein
MTAVIETRGLTKRYRGGQLAVDGLDLTVPAGSVYGYLGPNGSGKTTTIRMLMGLIEPTSGTAIVLGEPMPQSARTVLPRVGALIEGPALYGFLSGRDNLLRYDAADPTADPATRSRRVAAALDRVGLTGAAGKKAKAYSLGMKQRLGLAAALLQPRGLLVLDEPTNGLDPQGMREIRALVRELAADGTTVFLSSHLLDEIEQLCTHVAVMAQGRLLTQGPVAELAARARGRLSVLTPDTARAARLLVSLGVAGVTVEDGSRGEGGGRVTAEPPGEGTELSDLNAALVEEGVRVRGFGVERASLEDAFVALTGEGFDVAG
>NZ_CP016559.1|WP_009997278.1|2709878_2710901_-|ABC-transporter-permease
MSRDDTTAVDPAGGPVGGPAADRETGPETGPVADRPEAGSAPGAEPGRPGGAPGALWTLGLFRSELLVTLRRRRTLALLAVLAAVPVLIGLAVRIETGDGGSVGGHGEDGDGRGEGGGPAFVSQVTNNGLFLVFASLAATLPVFLPMAVGVVAGDAIAGEASAGTLRYLLVAPAGRARLLLAKYLTTLVFCLVATVVVAASALAVGALLFPLGGVTTISGTTIGFGAGLLRAVLVAAVVAASLSGLAALGLFVSTLTSSGVTAMAATVGLLITAQILDAIPQLDAVHPYLFPHYWLSFSDLLRDPVLWDGIARNLGLQLLWTAVFGSAAWARFTSRDITA
>NZ_CP016559.1|WP_003956217.1|2708692_2709664_+|M28-family-peptidase
MKISLPRRTATAAVIALAGLLATTAPAASAVPGAPTAPGTSARALAAPDIPVTNVKAHLTQLQSIATANGGNRAHGRPGYKASVDHLKAKLDAAGFITTVQQFSYLGTTGYNLIADWPGGDPNRVLMAGAHLDSVTAGAGINDNGSGSAGILETALAVAREGFKPAKHLRFAWWGAEELGLIGSRDYVNSLPSTERSKISGYLNFDMIGATNGGYFVYDDDPAIESALKGYLTGIGVATEPDTEGDGRSDHASFKNVGIPVGGLFTGAGRLKTAAQVQKWGGTAGRAFDPCYHRACDTLANIGDTTLDRSSDAIAHAIWTLSN
>NZ_CP016559.1|WP_003956219.1|2707763_2708210_+|hypothetical-protein
MALHWKLTIDAEDPLAQTEFWSAVLGYEIEDHSDLIRRLTEQGLLTEGLTTRAYGREVWRELAAVRHPDDPVDENGICHGRRLLFQRVPEAKTVKNRLHLDLHVGPERREAEVARLEKLGAKVLHRHNQPMGTWTIMADPEGNEFCVE
>NZ_CP016559.1|WP_003956220.1|2707145_2707742_-|hypothetical-protein
MTEAARGLILTPSDGRSFRFDPGALCLELLLTGGPGPLARWESLYTSADLVRWAGESRLPDGLAPVVTEPEVADARRLRDALHRITSARVHGRKLPAADMAVVNEAAALPPPVPCLTPEGERGWVPGASGSQVLSAVARDAVELFTGPWAGRVRECGADNCLLLFVDTSRPGRRRWCAMERCGNRHKVRAHRARPADS
>NZ_CP016559.1|WP_003956222.1|2706502_2707045_+|helix-turn-helix-transcriptional-regulator
MEEGTSKSPRHLAFTGFGDCGDPDPFQWDTREGCEVRQILDRVADKWSLLVIALLDSRVLRFTELRREIDGISQRMLTVTLRQLERDGLVTRTVHPVVPPRVEYALTALGCTLHTTIRSLVTWTEEHQQEIAAARAAYDIRAEREAQQAQEERERQEVQETVRAQETPGTVHGGAAAAAR
>NZ_CP016559.1|WP_003956223.1|2704938_2706387_-|MFS-transporter
MLTSDLPPHPPMSTERAPAPVEERPGGSAALSGRSWALLLVLCGAIFLEGIDVAMLAVAIPTIRADLGLSTGTAAWVVSGYVLGYAGFTLLGGRAADLLGRRRMFLGWLVVFLVFSAFGGLATEGWMLVVSRFVTGVASAFMTPAALSVITTSYPEGPQRNKALLVYAGTSAGGFSLGLVIGGLLTQIGWRWVFFAPVLLAAAILVAAVRLIPAERPPIRKGGFDLPGAATAAGAMLLLTYGIVRLEHGLDGWTFTLAAVGAGLLLAGLFVLVERRTPAPLVRLGILRRAPLVRADLGALLLLGSFMGFQFMTTLYLQELRGWGSLETSLALLVMGIDVVLAPTVTPILVNRFGYGRVILSGFALAALGYALFLPVGSDWTYLMMLPTLLSLGLAFGLAYGPLTIAATDGVDAGEQGLAGGLLQTATQFGAAVGVASVTAVYGLVGPGADGFRAALVVPVVMALVGVAVAVPGARRGAPGRR
>NZ_CP016559.1|WP_003956224.1|2704423_2704861_-|hypothetical-protein
MDIPPAAGPNGPNGAAPGCPLVGVVATYLPRLSEFAFEPGLVAAVDQHAAAVRDALLPGPRRSPEAGETHEACGAGEAHAAVPPTAPLSARTDFTPVRRDDLADYVLGFTDWLTETEWTEPVGYDFATLRLTAVCWLVREYDLLS
>NZ_CP016559.1|WP_003961482.1|2703528_2704350_+|hypothetical-protein
MSQSPLALSVDFGQGLTEAWSAVARFVPKLIAFLVILVIGWFIAKLIARVVDKVLRKIGTERLAERSGVAATLSGSKYDATGIITKIIYYGLLLIVLQLAFGAFGPNPISRMIEAVVAWLPRAIIALVIVVVAMAIARAVRDIVMGALGGQSYGKVLATVAWAFIVALGVIAALGQAGIATAITGPLLTAVLATVAGILIVGVGGGLINPMRERWDRWLSRAEQESTRARDSISAYQRGRADAQAGRPAPDTRAPGGRESGRGPEGRENIDPM
>NZ_CP016559.1|WP_003956226.1|2702256_2703306_+|EamA-family-transporter-RarD
MKRDGEERAGLLYGIGAYGMWGLVPLFWPLLEPAGAMEILAQRMVWSLVLVVVALLALRRWQWVRELLSNPRRLGLITAAAAVISVNWGLYIWAVNNERVIEASLGYFINPLVTIAMGVLLLNERLRPVQWAAVATAALAVLVLAVGYGRPPWISLVLAFSFATYGLVKKKVNLGGLESLAAETAVLFLPALGFLLWLGSQGEATFATEGVGHATLLALTGVVTAVPLICFGAAAIRVPLSTLGLLQYLAPVFQFLLGVLYFKEAMPPERWAGFTLVWLALAMLTWDALRTARRNKAAALRLAEQAGHSARTAAQAPAVPEPALPGPAPVPVPLPAPAPAPAPDADRRS
>NZ_CP016559.1|WP_003961479.1|2713780_2714947_-|CHRD-domain-containing-protein
MKRTKTILVGITAVVAAAGVGFAVLPAVADALSDTKGNGSNGSTGSAEGAGKAEDAGKAGSTGKVEGTEGAEGGGSAGAAGGTGGAGGHGSHAGHGAGEAVSAAGLDAAGKAKAWYFVASLNGANEVPVAGGPAVGDRDGRALQFVKVQGDTVSVAMKFRGVAKPTALHIHQGKRGTNGGVKVDFTPLLSRVTSLNGWTGAVTGSVKVRDAALLKSFVGDPNGFYANLHTAEFPGGAVRAQYHQVTQGLTFSKALENFQASVVEGQQIYACERGTNGTWSFQQRDVTARLGGHIGHSFVAPGSGTPQWIAPDRSAVTGSLVSSVDNGSRNIPELDLKATRSGRGAGLLATSHEILRLNTVGGVAPEGGCAKGATARVAYGADYVFIQK
>NZ_CP016559.1|WP_003956211.1|2715222_2716233_-|polyprenyl-synthetase-family-protein
MTDVGPFGLSVRDQALEADVHNGLSAVEAGLLDATKSEVPFITEAAQHLVRAGGKRFRPLLVMLAAQFGDPYSPGVVPAAVVMELTHLATLYHDDVMDEADVRRGVPSANARWGNSVAVLTGDFLFARASHILADLGPEAVRIQAEAFERLVTGQILETAGPREGGDPIEHYLDVIGGKTGSLIAVSGRIGAMMAGADERIVDTLTQYGERLGVAFQLADDVLDIASHSHESGKTPGTDLREGIPTLPVLRLRERAKATGEAADRELVELLDGDLADDDRLAEVLRRFRDHPALEQARRDTVRYAQEARATLAPLPDCPAKAALEELCDAVVHRAG
>NZ_CP016559.1|WP_003961478.1|2716472_2718527_+|CocE/NonD-family-hydrolase
MRHRLRFPYETSHQDVRIPVHGDLTLFARVWRPRTGEPVPALLEYSPERLTDTTVTRDAQRHPWYAGHGYASVRVEARGHGNSGGTPDPAGLPGGATALADAVDVIDWLAGQPWCTGRIGMFGLGWGGSCALATAARAPEPLKAVVAVCCGDDPHTNGGRYLGGAVLAESLHSASAALLSTGCRPPDPAHSGAPWRARWLERLETVEPAAHHWLAHQLRDDFWAAASPGPAAARPGPDLSAVRAAVLAVGGWWDPYRDTVLRLVGTLPPERVRGLIGPWSHQYPDHGRPGPAIGFLQETRRWWDRHLRGIENGVMDEPLLRTWSGDGTRGAGADGGSDDRPGPGAGRWTGTAAWPSPQVTPVAYELRGDPVPVASPQSTGLEAGPCRSTDGTTGGDQRADDACSACFEFPVAGEPVELLGTPRVTLLLRLGVPHGQAVARLCDVAPDGTSTRIALGALALSARHGTERAHAWPPGATEPVSFALAAAGHTFRPGHRIRLAVSSAYWPWLWPADDTAAGFVLVPEGSHLELPVRERRNGPSTAREPAPEREPEQAEPPLVGAAGTLEGERPARLLIREPGTGVHRSETVPVPGGTRVHPDGLEVTEEALQTWTIRAHDPLSAHALTVWRTRLHRPALPWDTTVETRSEIRCDADDFVLRDEVVCRDGREIVFHRTWEKRIPRLAG
>NZ_CP016559.1|WP_009997277.1|2718595_2719825_+|fumarylacetoacetase
MSEQSPLDLAGDDPFGPHNLPYGVFTTADEPGRRKVGVRIGNHVLDAGAAAAALGSPYAALLGGPGLDPLLAAGRTAWHDVRRALTAWVTVPAHRATVEPLLIPLPAVTMRLPYTVADYVDFYASEHHAANVGQIFRPGGEPLTPNWKHLPIGYHGRSGTVVVSGTDVVRPSGQRKAPADPAPVFGPSVKLDIEAEVGFVVGVPSAQGHPVPLAAFRDHVFGVSLLNDWSARDIQAWEYVPLGPFLGKSFATSVSAWVTPLEALDAARTAPPARDVPVLPYLDDTAEEEPGGFDLRISVAVNGQVVAEPPFASMYWTAAQQLAQMTVNGASLRTGDLYGSGTVSGPEPHQRGSLLELTWNGRDALELPTGRRTFLADGDEVTMTAWAPGPDGVRIGLGEVTGRIVPAPR
>NZ_CP016559.1|WP_003956208.1|2719946_2721596_-|NADH-quinone-oxidoreductase-subunit-NuoN
MSPVAVHTLWTTAAGPVDKIPAPDIEYAQLAPVLIVVGAAIVGLLLEAFLPRRARYPAQFVLTFFALAAAFVSVVALARSGYGTSKVNIAAMGAIAIDGPTLFLQGTILLASILAVFTFAERGLDPHAEGKPVDSFVAQAAAVPGSDSEKAAVKAGFTTTEVYPLALFAIAGLLVFPAANDLLTLFIALEVLSLPLYLLCALARRKRLLSQEAAVKYFLLGAFSSAFLLFGVALLYGYAGSVSYARIADVVDGSVRTIDPALADTMGNDVLLLIGTALILMGLLFKVGAVPFHMWTPDVYQGAPTPITGFMAAATKVAAFGALLRLLYVVLPGLRWDWRPVMWGVAIITMLGGAIVAITQTDIKRMLAYSSIAHAGFILVGVVAVNEDGVSSVLFYLAAYSFVTIGAFAVVTLVRDAGGEATHLSQWAGLGRRSPVVAAVFAVFLLAFAGIPLTAGFSGKFAVFKAAAEGGAEPLVVVGVIASAIAAFFYIRVIVLMFFSEPKPDGPTVAVPSGMTTAAITTGVVVTLILGIAPQYFLDLAGQAGVFVR
>NZ_CP016559.1|WP_003961477.1|2721592_2723164_-|NADH-quinone-oxidoreductase-subunit-M
MSFPLLTATAAVPALGAIVTAAVPAARRTAAKWVALFFSLVTLGLAAGVFVRFDPGGDRYQLTESHAWIKDFGVRYELGVDGIGVALIALTALLIPFVILAGWNDADPQETGSTRWRPTQGFFALILMVEAMVILSFEATDVFLFYILFEAMLIPMYFLIGGFGDRAHAGTDRNAAAQRSYAAVKFLLYNLVGGLIMLAAVIGLYAVAGTFSLSEIAAARAGGQLELATHTERWLFLGFFFAFAVKAPLWPLHTWLPNAMGEATAPVAVLITAVVDKVGTFAMLRFCLQLFPEASAWATPVILVLALVSIVYGALLAVGQRDIKRLIAYASISHFGFIVLGIFAMTSQGQSGATLYMVNHGISTAALMLVAGFLISRRGSRLIADYGGVQKVAPVLAGTFLIGGLATLSLPGLAPFVSEFLVLVGTFARYPVAGIVATSGIVLAALYTLVLYQRTMTGPVKDEVAKMPDLRARELAVVAPLIALLILLGVFPKPLTEIVDPAVEHTLSDVQKTDPRPDVEAAK
>NZ_CP016559.1|WP_003956206.1|2723169_2725074_-|NADH-quinone-oxidoreductase-subunit-L
MTNAENLIALLIGAPLLGAAVLLCGGRRLDRAGHWIGTALAGASFAIGAVLFLDMLGRSADERTLHQKLFSWIPVEGFQADVAFQLDQLSMTFVLLITGVGTLIHVYSIGYMEHDERRRRFFGYLNLFLAAMLLLVLADNYLLLYFGWEGVGLASYLLIGFWQHKPSAATAAKKAFLVNRVGDIGLSIAIMLMFTTFGTFAFGPVLGSVDETGEGRLTAIGLMLLLAACGKSAQVPLQSWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGAIFNAAPDAQLAVVVVGAVTLLFGAIVGCAKDDIKKALAGSTMSQIGYMILAAGLGPIGYVFAIMHLVTHGFFKAGLFLGAGSVMHGMNDEVDMRKYGGLRTYMPVTFITFGLGYLAIIGFPGLSGFFSKDKIIEAAFAKGGTEGWILGSVALLGAAITAFYMTRVMVLTFFGEKRWQPDARGELPHPHESPKSMTIPMVILAFGSVFAGGLFSIGDRFLTWLEPVTGAEHGHPPISAATVTASTVVALLIGVSIAWAMYGRRPVPVTPPRGSLLTRAARRDLLQDDFNHVVLVRGGEHLTRSLVYVDHTLVDGVVNGTAASVGGLSGRLRKLQNGYVRSYAVSMFGGTAVLIAATLLMRGV
>NZ_CP016559.1|WP_003956205.1|2725085_2725385_-|NADH-quinone-oxidoreductase-subunit-NuoK
MNPANYLYLAALLFTIGAAGVLIRRNAIVVFMCIELMLNACNLALVAFSRMHGNLDGQIIAFFTMVVAAAEVVVGLAIIVSLFRSRHSASVDDASLMKL
>NZ_CP016559.1|WP_003961476.1|2725381_2726299_-|NADH-quinone-oxidoreductase-subunit-J
MTGPIPLGTLAASTTSTGEAVQFWVLGTVAVLGALCTILMKRAVHSALCLAGTMVVLAVFYLANGAYFLGVVQIVVYTGAIMMLFLFVVMLVGVTAADSLKETLKGQRWLAALCGLGFGVLLVAGLGNASLNEFNGLGAANSEHGGNVEGLAALIFTKYVFAFEITGALLITATVGAMVLTHRERTEQARTQREQAEERVRAGVQLPPLPAPGVYARHNAVDIAGLLPDGTPSELTVSRTLRERGQIRDVSTQALDDLKALEQRSEERLGRGGHGPDAPGPAGDGPDDRTRNTDDRDRDGEEAHR
>NZ_CP016559.1|WP_003961475.1|2726295_2726916_-|NADH-quinone-oxidoreductase-subunit-NuoI
MSEESEKFQNPVAGFGVTFKAMFKRRLTEQYPEEQKVTAPRFHGRHQLNRHPDGLEKCVGCELCAWACPADAIYVEGADNTDEERYSPGERYGRVYQINYARCILCGLCIEACPTRALTMTNEFELADSSRENLIYTKEQLLAGLTEGMVDSPHALYPGMDEGDYYRGAVTGAAPGTVRQTAVSQGEKDEKDKKDESDEKAKEVDA

Crispr_ID: NZ_CP016559_9

• CRISPR_ID: NZ_CP016559_9
• CRISPR_location: 2805944-2806029
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_9

Consensus_repeat	Method
TCCGGCTCGTCCTTCTTCACGTCCGG	CRISPRCasFinder

spacers of NZ_CP016559_9

>9.1|2805970|34|NZ_CP016559|CRISPRCasFinder
GTCCGGCTCGACGTCCGGCGCCGCGTCCTTGACG

CRISPR arrays and Neighbor proteins around NZ_CP016559_9

CRISPR arrays

The CRISPR arrays of NZ_CP016559_9

>merge|NZ_CP016559|9|2805944-2806029|CRISPRCasFinder
TCCGGCTCGTCCTTCTTCACGTCCGGGTCCGGCTCGACGTCCGGCGCCGCGTCCTTGACGTCCGGCTCGTCCTTCTTCACGTCCGG

>NZ_CP016559|9|8|2805944-2806029|CRISPRCasFinder
TCCGGCTCGTCCTTCTTCACGTCCGG	GTCCGGCTCGACGTCCGGCGCCGCGTCCTTGACG
TCCGGCTCGTCCTTCTTCACGTCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003961443.1|2798579_2799869_+|CHAP-domain-containing-protein	unknown	unknown	gnl|CDD|377495
NZ_CP016559.1|WP_003953273.1|2797223_2798444_+|hypothetical-protein	unknown	unknown	gnl|CDD|373106
NZ_CP016559.1|WP_003953270.1|2796370_2796676_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003953284.1|2813991_2815146_-|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl|CDD|377122
NZ_CP016559.1|WP_003953280.1|2808914_2809124_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP016559.1|WP_003961442.1|2800121_2801297_-|hypothetical-protein	unknown	unknown	gnl|CDD|237537
NZ_CP016559.1|WP_003961438.1|2811079_2813650_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|368582
NZ_CP016559.1|WP_003953279.1|2807846_2808707_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP016559.1|WP_003953285.1|2815264_2815837_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003953268.1|2794088_2795003_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003953266.1|2792695_2792983_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_065757117.1|2801649_2803545_-|hypothetical-protein	unknown	unknown	gnl|CDD|369468
NZ_CP016559.1|WP_003953289.1|2820410_2821406_+|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238042
NZ_CP016559.1|WP_003953287.1|2816755_2819350_-|bifunctional-FO-biosynthesis-protein-CofGH	unknown	unknown	gnl|CDD|236422
NZ_CP016559.1|WP_003953288.1|2819390_2820233_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|131480
NZ_CP016559.1|WP_003961439.1|2809546_2811076_+|Na+:solute-symporter	unknown	unknown	gnl|CDD|271371
NZ_CP016559.1|WP_003953271.1|2796906_2797098_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003953269.1|2795185_2796181_-|erythropoiesis-stimulating-protein	unknown	unknown	gnl|CDD|225107
NZ_CP016559.1|WP_003953278.1|2806788_2807508_+|hypothetical-protein	unknown	unknown	gnl|CDD|377552
NZ_CP016559.1|WP_003953265.1|2791247_2792237_-|porphobilinogen-synthase	unknown	unknown	gnl|CDD|236450

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003961443.1|2798579_2799869_+|CHAP-domain-containing-protein	gnl|CDD|377495	pfam05257, CHAP, CHAP domain. This domain corresponds to an amidase function. Many of these proteins are involved in cell wall metabolism of bacteria. This domain is found at the N-terminus of Escherichia coli gss, where it functions as a glutathionylspermidine amidase EC:3.5.1.78. This domain is found to be the catalytic domain of PlyCA. CHAP is the amidase domain of bifunctional Escherichia coli glutathionylspermidine synthetase/amidase, and it catalyzes the hydrolysis of Gsp (glutathionylspermidine) into glutathione and spermidine.	1.95733e-05
NZ_CP016559.1|WP_003953273.1|2797223_2798444_+|hypothetical-protein	gnl|CDD|373106	pfam14517, Tachylectin, Tachylectin. This family of lectins binds N-acetylglucosamine and N-acetylgalactosamine and may be involved in innate immunity. It has a five-bladed beta-propeller structure with five carbohydrate-binding sites, one per beta sheet.	2.68676e-06
NZ_CP016559.1|WP_003953280.1|2808914_2809124_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	8.91854e-14
NZ_CP016559.1|WP_003961442.1|2800121_2801297_-|hypothetical-protein	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	1.61675e-05
NZ_CP016559.1|WP_003961438.1|2811079_2813650_-|NACHT-domain-containing-protein	gnl|CDD|368582	pfam05729, NACHT, NACHT domain. This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.	5.69177e-26
NZ_CP016559.1|WP_003953279.1|2807846_2808707_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.32515e-12
NZ_CP016559.1|WP_065757117.1|2801649_2803545_-|hypothetical-protein	gnl|CDD|369468	pfam07690, MFS_1, Major Facilitator Superfamily.	0.00637675
NZ_CP016559.1|WP_003953269.1|2795185_2796181_-|erythropoiesis-stimulating-protein	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.60768e-08
NZ_CP016559.1|WP_003953289.1|2820410_2821406_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.59111e-10
NZ_CP016559.1|WP_003953287.1|2816755_2819350_-|bifunctional-FO-biosynthesis-protein-CofGH	gnl|CDD|236422	PRK09234, fbiC, FO synthase; Reviewed.	0
NZ_CP016559.1|WP_003961439.1|2809546_2811076_+|Na+:solute-symporter	gnl|CDD|271371	cd11477, SLC5sbd_u1, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	5.75464e-146
NZ_CP016559.1|WP_003953288.1|2819390_2820233_+|alpha/beta-fold-hydrolase	gnl|CDD|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	3.63867e-20
NZ_CP016559.1|WP_003953284.1|2813991_2815146_-|ADP-ribosylglycohydrolase-family-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	7.85259e-37
NZ_CP016559.1|WP_003953278.1|2806788_2807508_+|hypothetical-protein	gnl|CDD|377552	pfam05719, GPP34, Golgi phosphoprotein 3 (GPP34). This family consists of several eukaryotic GPP34 like proteins. GPP34 localizes to the Golgi complex and is conserved from yeast to humans. The cytosolic-ally exposed location of GPP34 predict a role for a novel coat protein in Golgi trafficking.	2.4944e-43
NZ_CP016559.1|WP_003953265.1|2791247_2792237_-|porphobilinogen-synthase	gnl|CDD|236450	PRK09283, PRK09283, porphobilinogen synthase.	0

Protein sequences

>NZ_CP016559.1|WP_065757117.1|2801649_2803545_-|hypothetical-protein
MSTAEPVRTDGHSTRTGPAGSTGSAGPAGPRIQGTAPQAGESGGPDRRGPGAAGVLADARDRLSRRPVLVATAVAAFTHVLWFFFFANSGGDLAAQDAWAEFVGRHPDSAYNLAWYGGMHPVSYSVVSPYLMSVIGVRPTMMVAGTVSAALTALILVRLRAVRNPLACALAGVFAFLCNALSGRVTFGLGMMFAVGAVAAVFCWPHRWRYHRWAKGAVAAPLAALATASSPVAGLFLGVVAAALFLNGRRPGAYAIGLPPVAVVGLSAWLFPFSGTQPMSIASSSLPFVYGVLVCLLVPKEWRTVKVASGVYALGVFLAWAIDSQIGSNISRLPMLFAGVALLAVLPYTVPRSRKWYALVLAVVGMNVWVGFKGVDDILRTAPTASWNFELAPLVNKLQEVDAEKGRVEVVPASSHREASALAPYVHLARGWNRQADMERNAIFYDKENPLTAVDYRAWLERWAVRYVVLPEGTPDVGAEREAELVQGGLPYLERIWGDANWQLFKVRDPVPMADPPATVEQATAGEVRIRVAQEGRVRIRIPYSPWLSLVDEKGDKVESPEETEESQQRPEGSPKSFTNPGGCLIKLDEDDEGDEWTELVAPRAGTYRLAAPYDIQRGTPCPEEMRQELP
>NZ_CP016559.1|WP_003961442.1|2800121_2801297_-|hypothetical-protein
MRCPVCGAPPGPGAGDWAARDTVLGRFALLSRTGKILLVGGVVLTALALAASVMTLRGGESPRARAGAPKDPGLLPESLGGLGGLGGVPQRIEPSPPAGRSAGGSASASVSAGLAAGSALGTAGSGDREGGSAGGRGGPLSPSAAPVEPPAEASETSGTPGAAGLPDAVPERPSTGAAGGAGGSGPGASGGPGSGSGSGSGSGSGSGPGSGSEGGSASVQPLRGAYSAWAGPGCTGGGRYREHGRYQDGDRGWYARPQGGHRGHGCDGRFSALPMSGRAHQDSGGSAIWAWYVGSGYRECSLTVVVPRGERDRDVAGAPSVYQVMAAPVEGGGPIQTFEIDQVSRRGDRVVVPGALVSDRHLTVRLLDRGEGREGGHHAAAQIRADCRTAA
>NZ_CP016559.1|WP_003961443.1|2798579_2799869_+|CHAP-domain-containing-protein
MFPTSKKLRTTVAGLALTAASMGLVTATGAQPAVAAEVCTGTASVYGILGDGRLTYSAINTKGDRLKTLIGPDLGFTPKAMATLNFNTILVTSTAGALYRVDVLTNNNALELSGVEKIADSGWTHDKLAYDGYGHLYGTTAAGNLLQYLVSQDKPQGSQHIGQRKEIGTGFVLKTLTATGKDRLLATAADGRLLSYKIIGSAWKRDDLKNDGWSAFDELTSSGGGFYFGRIPTTGAMYWYKDGNISDGSGSDIVYHTNDPVDTSGWTQKLLSAAPDTTSCKQVNTLGQDIAADANREVGNNFNDFDFNHARAWCAEFVEYIWAGNSVDHSRELDARAISLKEYGQRHGTYRTSGPKVGDAVLYDVDRNLNDGEADHVNIVVAVSADGTQIQTVGGNESGKVSKAGWFNWDTASSPVGAGPVLAFVSPKG
>NZ_CP016559.1|WP_003953273.1|2797223_2798444_+|hypothetical-protein
MPEGNPVPAIRPALRAATGALLSGAVGAGLLTAATVATAPAAQAATSCSGTASVYGILDDGRLTFSAINPARGDLTKVRIGPDLGFTPKAMATLNFNTVLVTSTAGALYRVDVLTNNNALELSGVEKIADSGWTHDKLTYDGHGHLYGTTSDGTLLQYLVSQDKPQGSQHIGQRKEIGSGFVLKTLTAAGDDRLLATTSTGALYSYKINSAGAWDRDDLKTSGWSAFDQLVSPGGGLYYGRMGTTGAMYWYKDANPNDGSGSDITYHNDDPVNTDGWTQKLLSAQPNTFKCTTTAPETVDRDNIAQVKAAGRNLMAQRNSAWNTAAQWSCLERLWDKESGWRWNADNPSSAAYGIPQANPGSKMGLMGADWATNPLTQIKWGLYYIENRYDSPCGAWNFFQNNNWY
>NZ_CP016559.1|WP_003953271.1|2796906_2797098_+|hypothetical-protein
MSATRIAQATAVAAFVLALGTPAVASAAGHSAPVRATSVTALQPSFTTNDMSWQIAPYDMSWQ
>NZ_CP016559.1|WP_003953270.1|2796370_2796676_+|hypothetical-protein
MYLVHARFETPPDTEIPFDLRQLSRSLLTDEDRIEHLSVHRRPPRHFVLGFYLVAGSLAEAESRAERVSRRLLDSGRLPSARLLKAEAPLLRPELFGSGTS
>NZ_CP016559.1|WP_003953269.1|2795185_2796181_-|erythropoiesis-stimulating-protein
MLTGLGLSAAAESVYRAMLLHPRAGVAAIAATTGDSEAEVREALDELSELALVRASAEDEGRLRVVSPDIGMEILMARRQAELAAEQQRLEASRAAAAQLISEYAELRPATPHPGVEQLIGLDAVRDRLVVLTRELKEELMAFSPDSALTESAITSSRPLNEELLARGVRMRTIYLDSVRNSRPSIEHANWLAELGGQVRTVAALPTRMLIVDRGTAVIPVSSDNTAAGAVVLTGQGMLTALCALFEATWAAAHPLAESTTRDPHGLTPQQSVALHLLADGHTDDSVAKRLGVSPRTARRMANDLMERLEARSRFEAGVRAVQRGWLPNEE
>NZ_CP016559.1|WP_003953268.1|2794088_2795003_+|hypothetical-protein
MRTKTVLVTPDMCVKWMKNRVCNCVPLRSYNVEKFREILRTGQFRTTHQGFALDSHGCLIDGQHRAQAIIDTGISVTAQVTYDLDPDTFAAIDGGRVRTAGDHVAQASGMTQNNANYYSASLKILRNRAQGLHWTRWTTGKITADEIPELMSSWPIPESRINYMLTKGRQCHASGTGLLISHHIILEKWPESVVNLFFEGIGDASRDYVGKDPRAVYTNTMLNVNKGVISRDSVQQAAQAIKAFNALVSGETIGTLKKMKMGGVKARRDRETGEKIEQPYLADRFPSVIGVQTISQNWLNTDDQ
>NZ_CP016559.1|WP_003953266.1|2792695_2792983_-|hypothetical-protein
MVWWFGRTELVAGAVVLTAAALVGAGAELRSPPVLDHGPVVIGERAERERAEQAERAERAERAERGRRAGREPCAGTDTDTRTDSGHRRPCHPRG
>NZ_CP016559.1|WP_003953265.1|2791247_2792237_-|porphobilinogen-synthase
MSAYGSFPGARPRRLRTTPAVRRMVAETRLHPADLILPAFVREGVSEPVPISAMPGVVQHTRDTLRKAAVEARAAGVAGIMLFGVPEDSKKDALGTAGTDPDGILQVAIRDVRSEVGDDLVIMSDLCLDEYTDHGHCGVLDADGRVDNDATLERYAEMAQVQADAGVHMVGPSGMMDGQVGVIRDALDTIGKEDVSILAYTAKYSSAFYGPFREAVGSSLTGDRKTYQQDSANVRESLRELALDLDEGADIVMVKPAGPYLDVLAKIAESVSVPVAAYQISGEYSMVEAAAEKGWVDREKAILETLTGIKRAGADMILTYWATEVAHRL
>NZ_CP016559.1|WP_003953278.1|2806788_2807508_+|hypothetical-protein
MGRSRRTLPEELLLLALDPTTGTTAQPQSLDLGLAGAQLVELALAGRIAPDGDRIAVVMPRPTGDPTLDSALELLRRRGSPVRAVHWIGGPRLGLRQIYLLHLERCGMVHAVAGQMCGVLPTTRYQATDTAISRDIRSRLDSAIRTGVPPDPRTAALAALAHAVGLGKHLYPGNEGRSSRSRLRDLIRHDPMGGLVAHAVMDVQNGVAAQPRRAPATNGRQPAVSMQARRGGMVRVAAH
>NZ_CP016559.1|WP_003953279.1|2807846_2808707_+|helix-turn-helix-domain-containing-protein
MASNVNPTVRRRRLGLELRRLRELKGMTAEEVAERLLVSQSKISRLENGRRSISQRDVRDLCGVYEVDDHRIVDSLMQMAKDSRQQGWWHAFGDIPYSVYIGLETDAASLRVYEPQVVPGLLQTRPYAESLIAGALPESSTADIEKRVSVRMRRQDRVHAEELPLRLWAVVDEAALHRIVGGKALMREQLEYLIELSRLPHVTVQVLPFEMGAHPGINGQYAILEFPDATDSSVVYIEGVTSDLYLEKANDVHKYTVMYEHLRAQALNADQSRAFIENIAKRYTML
>NZ_CP016559.1|WP_003953280.1|2808914_2809124_+|DUF397-domain-containing-protein
MAIIEGATESWTKSSYSGGNGACVEVKSPVTRAISVRDSKVTAGAELTFVPGSWNAFVGEVGRGSFDLG
>NZ_CP016559.1|WP_003961439.1|2809546_2811076_+|Na+:solute-symporter
MNSLDWTVLIGYFGVMVAIGLWSHKRVDNVSDFFTAGGKMPWWLSGISHHMSGYSAVMFTGYAGIAYTYGVTSFVTWSLPIAIGIYIGSTLFAPRLNRLRSRLHVASPLEYLKNRYNLKTQQALAWSGVLLKIVDVGAKWAAIATLLSVFTGISLNQGILITGVITGVYCTIGGLWADALTELGQFIIQLFAGLAMLFAVMRELDGFSTLWTIWDEPQLQGHAEPTAGPYTVTFLLAFLFIKTFEYNGGMWNQAQRYMATANAREATRSARLSAVLWFVWPLVLFFPMWCAPLLVKTEKPDASDSYALMTEQLLPHGLLGLVIVGFFSHTMAMCSSDANAIAAVFTRDIAPVLSKKARSWTEQAGLIAARWSTIAFLALSMAIATQVNSPTFKDIITVVIKWVAGLMGPIAIPFMLGMLRSFRRSGPTAALTSWAAGLLAFFLVNYELNGDQRTDIALQYQVSVPLAISLVLYIAIGFLKPENTAERDALIERINTDGDEAEAPGTVRR
>NZ_CP016559.1|WP_003961438.1|2811079_2813650_-|NACHT-domain-containing-protein
MDAAAAVAARLASTAVAPLVRKLFTPQPDGARLVDKPVRISGLVSFRGERRTLGEKELRRLATELVDRAAASYGPHEAPSPETRRELADALALALHSLGDLDMDDVQAVRLGPEAFTARLARPRHLSAAAEAYYEPLLHTAGLHILNFFSQRSSFVPRTLTEQTRTLDRLVALTDLLLERLPSRPAEDARFEDRYTRHIAAKHSELTIHGLDLRQARAWHLDSAYVSLEAADATTSVPRPADRALSGRDRVLLRGGAGSGKTTLVQWLAVTAARQKYEEFGDHLDHLVGRIPFVLPLRRVIRDGRPPTPDEFLRAVRSVLAGAEPPGWTDRVLSAGRALVLVDGIDEIPQRERETTRRWLRELMADFPGNLWLVTARPSAVDADWLAAEGFTELTLATMSHDDVTRFVHRWHTAAAAPASLAGTLLTAVRVSTDLGRLAVNPLMCGMLCALHRERNGFLPHSRKELYEAALRMLLERRDLERGVQDELSLSSETQILLLQRLAHWMIRNDTAEMERADAVAQLGRALELMHHVTAPADRVLTHLLERSGLIREPAHDRIDFVHRTFQDYLGAKALVEEGDFPLLLKNAHRDQWEDVVRMAVALGRPAERDRILRGLVAGDSDELFDLRGVLLAFACLEQAPEVYPETRSLITGLTAEIIPPKNTPHAMALSNFGGSLALGLLPGPEGLSDDEARGTVLAASYIGTDAALPVLARFRHHPSLRIRSQLVWSWYRFDCRRYADEVIAHLDPADLYFTVPGVEHAHALTALGGRERVHLPSGADPSAVAEHLDTERVTHVWVELGRTSEEYWAWVRDFPRLHTLVLEDDAVRAAASPYLPPHLTVLPWPGEGRYTERTP
>NZ_CP016559.1|WP_003953284.1|2813991_2815146_-|ADP-ribosylglycohydrolase-family-protein
MSAAATAVWGRTEQQDFRARVRGALLGAALGDALGAAVDPLPYEEIRETHGPDGLTDLVPVHGRRGAVTAATQLTLFTVDGLIRAQVRRDTGAWHPPTDVHRAYLRWAATQRDWGPDERRKDNGWLAQEEWLYARRAAPRASLLGLGDDTMGTLEAPKNPTARDGGALARSAPFGLLVGWEPQLVCQLALECAAQTHGHPTAFLAAGACAVIVHGLARGETLEAAVRRALALVAVHPGHQQVTEGLTAALAAVREGVPGPGRVGAFHTPGDDTDDGDGPAGGSHAGADLAAAVYAALVSEDMRHGLRLAVNHDGASTVTGAVTGALLGALHGETALPPAWLCELEGRPTVLALADDFALETTQGPALHGPTAAAPGWLARYPRA
>NZ_CP016559.1|WP_003953285.1|2815264_2815837_-|hypothetical-protein
MARQISSAALVTGLTSAALVGVLLLAVQAGQAAPQNTAARKPAPGASGSPEAKDRTREPAEQPTALPADSGTGKRVVYSLGRDRVWLVDHSGRPVSTFTVWPGNVEPALGTHRVTDRQPSITGNDGVSVENIVYFSGSKEGLPIAFSAAVDGSSPKPVPGKQTGAIRVRTADGDRIWDFTVVGSDVVVVR
>NZ_CP016559.1|WP_003953287.1|2816755_2819350_-|bifunctional-FO-biosynthesis-protein-CofGH
MLGSMTDHVPVPPTENAMRRALRRARDGVALDVTEAAVLLQARGSDLTDLCRSAARVRDAGLEAAGRPGVITYSKSVFIPLTRLCRDKCHYCTFATVPGKLRRAGHGMFMSPDEVLAIARRGAELGCKEALITLGDKPEDRWPEAREWLEAEGYDDTIAYVRAMSIRILEETGLLPHLNPGVLSWTDFQRLKPVAPSMGMMLETTATRLWSEPGGPHHGSPDKEPAVRLRVLEDAGRSSVPFTSGLLIGIGETHEERAESLFALRRVSRTYHGIQELILQNFRAKPDTAMRGMPDAELDELVATVAVARHLLGPAACLQAPPNLVDAEYARLIGAGIDDWGGVSPLTPDHVNPERPWPQIDELAEHSAAAGFRLAERLCVYPEFVTRGEPWLDPRVLPHVRALADPATGLADPGAHPAGLPWQEPDEGFTSTGRTDLHRTIDTEGRTHDRRDDFDAVYGDWDALREAAAPGMVPQRIDTDVRQALRTAADDPTRLTDDEALALLHADGPALDALTRIADELRRDVVGDDVTYVVTRNINFTNVCYTGCRFCAFAQRRTDADAYTLSLDQVADRAAQAWDVGAVEVCMQGGIHPDLPGTAYFDIARAVKTRVPGIHVHAFSPMEVVNGASRTGLSIREWLTAAKEAGLDSVPGTAAEILDDEVRWVLTKGKLPAATWIEVISTAHELGIRSSSTMMYGHVDQPRHWLGHLRTLARIQQETGGFTEFVTLPFIHTNAPVYLAGIARPGPTDRDNRAVTAMARLLLHPHITNIQTSWVKLGAEGAAEMLRSGANDLGGTLMEETISRMAGSRYGSYRSVRDLVAIAELAGRPARSRTTLYGEVPGERTRAAEASDGQLPELLPLVTD
>NZ_CP016559.1|WP_003953288.1|2819390_2820233_+|alpha/beta-fold-hydrolase
MGNGGGGVSEEASGTGVVFHGGDGCPLRARVSGTGPPVVLLHGGGPDHRSLLPLAARLSSAYTVVLPDVRGFGRSLCAHEERHTWSGYAADVVALLDRLGLERAVVGGTGLGGTVALRTAVEHPERVRAVVVVSVEDIEDDAAKEAERVFFERFAERVRAGGVAAGWAPVLPDLAPLIGHLVREAIPRADPASVAAFCAIGRDRAFREVSDLAVVGVPALIVPGTDVRHPTELAERVAAVLPRGRLAPVTLSHELLTAEDLGAAMGPVVAEFLAGLDGTR
>NZ_CP016559.1|WP_003953289.1|2820410_2821406_+|winged-helix-turn-helix-transcriptional-regulator
MVQVGRAQGGTVDIEFTAEDMARTRFAVSPLWEVVASVRVLKGGDDQGMHRRWAEHVRPLLAAERLDLTPLSRLIAVPAECVPSFLVPPPTTPQPSLAVELAALRATPPELLRTTTPGVEACVGELRADPGRELGRLADLISAYWEIAIAPFWPRMQALFEGDILHRAIHLAEGGARRLFDDFGPQVTWDSGTLQLIRRSSRGTKRLDGRGLLLVPSAFAWPRIFSNLGSGAWQPTLRYPPRGIGTLWEHGPRPCSDALAGVLGRSRALLLAELTHPASTTELARRLGLSAGGVSQHLTALRAAGLVSAHRTGRVVLYARTSVGEALVGVR

Crispr_ID: NZ_CP016559_10

• CRISPR_ID: NZ_CP016559_10
• CRISPR_location: 3003035-3003123
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_10

Consensus_repeat	Method
ATCGACGCGGGCGCCGAGCTGGACCCCGTCCA	CRISPRCasFinder

spacers of NZ_CP016559_10

>10.1|3003067|25|NZ_CP016559|CRISPRCasFinder
CCCCGTCAAACCGCCCCGGCGGCTC

CRISPR arrays and Neighbor proteins around NZ_CP016559_10

CRISPR arrays

The CRISPR arrays of NZ_CP016559_10

>merge|NZ_CP016559|10|3003035-3003123|CRISPRCasFinder
ATCGACGCGGGCGCCGAGCTGGACCCCGTCCACCCCGTCAAACCGCCCCGGCGGCTCATCGACGCGGGCGCGGAGCTGGACCCCGTCCA

>NZ_CP016559|10|9|3003035-3003123|CRISPRCasFinder
ATCGACGCGGGCGCCGAGCTGGACCCCGTCCA	CCCCGTCAAACCGCCCCGGCGGCTC
ATCGACGCGGGCGCGGAGCTGGACCCCGTCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003957786.1|2994767_2995262_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003958996.1|3019477_3019717_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957796.1|3002465_3002753_+|DUF2530-domain-containing-protein	unknown	unknown	gnl|CDD|378488
NZ_CP016559.1|WP_003957794.1|3000487_3000670_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003959003.1|3013859_3014759_-|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NZ_CP016559.1|WP_003958997.1|3018904_3019288_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP016559.1|WP_003959001.1|3014649_3015036_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003961325.1|2997844_2998429_-|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|224431
NZ_CP016559.1|WP_003961322.1|3005866_3008680_+|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NZ_CP016559.1|WP_003957792.1|2998538_2999879_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP016559.1|WP_003959000.1|3016569_3017046_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957788.1|2996535_2997072_-|hypothetical-protein	unknown	unknown	gnl|CDD|373593
NZ_CP016559.1|WP_003957795.1|3000865_3002314_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP016559.1|WP_003957787.1|2995427_2996417_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381313
NZ_CP016559.1|WP_009997173.1|3017122_3017869_+|futalosine-hydrolase	unknown	unknown	gnl|CDD|236194
NZ_CP016559.1|WP_003958998.1|3017865_3018705_+|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353
NZ_CP016559.1|WP_003957793.1|2999903_3000371_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP016559.1|WP_065757125.1|3015075_3016428_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP016559.1|WP_003961327.1|2997119_2997485_-|hypothetical-protein	unknown	unknown	gnl|CDD|373593
NZ_CP016559.1|WP_003961321.1|3009698_3012938_-|hypothetical-protein	unknown	unknown	gnl|CDD|237603

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003957796.1|3002465_3002753_+|DUF2530-domain-containing-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	0.000615177
NZ_CP016559.1|WP_003959003.1|3013859_3014759_-|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	2.84484e-106
NZ_CP016559.1|WP_003958997.1|3018904_3019288_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.78611e-26
NZ_CP016559.1|WP_003961325.1|2997844_2998429_-|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|224431	COG1514, LigT, 2'-5' RNA ligase [Translation, ribosomal structure and biogenesis].	7.35222e-35
NZ_CP016559.1|WP_003957788.1|2996535_2997072_-|hypothetical-protein	gnl|CDD|373593	pfam15138, Syncollin, Syncollin. This family has a role in zymogen granule exocytosis.	0.00572063
NZ_CP016559.1|WP_003957792.1|2998538_2999879_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.51422e-77
NZ_CP016559.1|WP_003961322.1|3005866_3008680_+|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	3.23972e-05
NZ_CP016559.1|WP_003957795.1|3000865_3002314_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	3.59206e-108
NZ_CP016559.1|WP_003957787.1|2995427_2996417_+|aldo/keto-reductase	gnl|CDD|381313	cd19087, AKR_AKR12A1_B1_C1, AKR12A, AKR12B, AKR12C families of aldo-keto reductase (AKR). Streptomyces fradiae TylCII, Saccharopolyspora erythraea EryBII, and Streptomyces avermitilis aveBVIII are founding members of aldo-keto reductase family 12 member A1 (AKR12A1), B1 (AKR12B1), and C1(AKR12C1), respectively. TylCII acts as a NDP-hexose 2,3-enoyl reductase. EryBII is a mycarose/desosamine reductase involved in L-mycarose and D-desosamine production. aveBVIII functions as a dTDP-4-keto-6-deoxy-L-hexose-2,3-reductase.	4.75681e-162
NZ_CP016559.1|WP_003961327.1|2997119_2997485_-|hypothetical-protein	gnl|CDD|373593	pfam15138, Syncollin, Syncollin. This family has a role in zymogen granule exocytosis.	0.000151941
NZ_CP016559.1|WP_009997173.1|3017122_3017869_+|futalosine-hydrolase	gnl|CDD|236194	PRK08236, PRK08236, hypothetical protein; Provisional.	8.68712e-66
NZ_CP016559.1|WP_003958998.1|3017865_3018705_+|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.10735e-139
NZ_CP016559.1|WP_003961321.1|3009698_3012938_-|hypothetical-protein	gnl|CDD|237603	PRK14083, PRK14083, HSP90 family protein; Provisional.	0.00523489
NZ_CP016559.1|WP_065757125.1|3015075_3016428_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.31089e-26
NZ_CP016559.1|WP_003957793.1|2999903_3000371_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.23843e-21

Protein sequences

>NZ_CP016559.1|WP_003957796.1|3002465_3002753_+|DUF2530-domain-containing-protein
MAKWTPKHEAPEPLEGPVVGTITGGTIIWFVLFLVQIPFYGWFEERGLMWWVWTCLAGAGLGLIGIWYVRGREAALKRAEAAGEREERAEPAERE
>NZ_CP016559.1|WP_003957795.1|3000865_3002314_-|NCS2-family-permease
MTPTASAAAPEHQPQGPLSGLDRFFKISERGSTVAREVRGGFATFFAMAYIIVLNPIILGSAVDMNGHRLDNAQLVTATVLTAAFSTLLMGVIGNVPIALAAGLGVNTVVALQLAPRMTWPDAMGMVVLAGFVVMLLVATGLRERVMSAVPNSLRKGIAIGIGLFIMLIGLVDAGFVSRIPDVAQTTVPLTLGQGGHLMGWPVLVFVLGALLTLVLIIRKVQGAILISIVAMTVLALIIEAIAELPKGSWGLTTPQWPGNPLSTPDFGLVGEVSLFGGFEKVGVLTGCLFVFTVLLSCFFDAMGTILGVGDEAKLLDKDGNLPGINKVLIVDGIAVASGGATSSSATTCFVESTAGVGEGARTGLASVVTGALFSVALFLTPLATMVPSQAATPALLAVGFLILAGSIRDIDWTDWTLAVPAFLAMVMMPFTYSITNGIGIGFITFCVLRLAVGRGREVPMAMYVVSAVFVFYYAMPALGLT
>NZ_CP016559.1|WP_003957794.1|3000487_3000670_+|hypothetical-protein
MGSTVLSLRIDGELLERIRLRAAHRRMSVQDYVLRTLKQDDFDERFRAALEETERLYGRA
>NZ_CP016559.1|WP_003957793.1|2999903_3000371_-|MarR-family-transcriptional-regulator
MSDQSPGGADHAARAEAEDAAAINALRSSVMRLGRRLKHQRVDESLSPTEMSVLGTLARCGSATPGELARKEHVQPPSMTRIVALLEAKGLVRLEPHPDDRRQKVVSRTERAEAMLEESRRKRNAWLADLAEGLDEDEWAKLRAAAPVLEKLAHL
>NZ_CP016559.1|WP_003957792.1|2998538_2999879_-|MFS-transporter
MRTGPGADSAPAPVPTTTFGSLKIRNYRLFALGALISNTGTWMQRIAQDWLVLTLTGSASAVGITIALQFLPMLLFGLYGGVLADRLPKRPLLLATQSAMGLTGVALAVLTLSGQVEVWHVYLTAFLLGLVTVVDNPARQTFVSELVGPAQLSNAVSLNSANFQSARLIGPAVAGVLITAVGSGYAFLFNGVSFLAPIVALLLIRPAELHRSERAPRGKGQLREGLRYVSAHPELIWPIVLIGFVGTFGFNFPIWLTAFVHEVYDSGAETYGLLNTLMAAGSLAGALLAARRGTSRLRFLVGAALLFGVLEVLAALAPGFWLFALLMVLVGMVGLTVNVTANSSVQTATDPAVRGRVMSLFMMVFVGGAPLGGPLFGWLTDAYGPRVSLAAGGVISFLAAAAVGLLLARAGGLRLRVDLRRGHKHLAFVPRQREPRPSRKPLTTAA
>NZ_CP016559.1|WP_003961325.1|2997844_2998429_-|RNA-2',3'-cyclic-phosphodiesterase
MRLFAAVLPPPGATAELADAVARLRGLPDAGRLRWTGRAGWHFTLAFMGEVDGAVLPELSARLARAARRTRAFGVRLHGAGQFGGRVLWTGAAGDIDGMRMLAERSYAAAARSGVPMEEHRAYRAHLTVARSREDVDLAPFVAGLAPFEGTPWDVTRIALVRSRLPTGGTPGEQPRYETVGAWDLGSGTSGPAG
>NZ_CP016559.1|WP_003961327.1|2997119_2997485_-|hypothetical-protein
MAVAAGLALALGAGGTAEAAPRTTRVGSGEYLMAIVFEHDYFRGAYLELWAELCSPSTHLQYFRLPPSWNDKASSIRVRRGCDVYAFEHSDMNGGRLHVGSDQAYLGVWNDRISSFTVQYP
>NZ_CP016559.1|WP_003957788.1|2996535_2997072_-|hypothetical-protein
MAPPNPSHSPCSPYSSPCSSSSASSSWRATMFQRIRTIRRHGRSPGCTGRTGPAAVLAAVASTVLALGTAGTAQAAPATAVVGSGDIVMGVVYKDAYYRGGAIELRGQRCSAQVPAQLVRTLPWNWNDKISSIQVSDSCDTMIYEHGFNVGERFRVSSDLPILGPWNDRISSLAFIPK
>NZ_CP016559.1|WP_003957787.1|2995427_2996417_+|aldo/keto-reductase
MEYTQLGRTGLKVSRIVLGTMNFGPFTDEADSHAIMDAALGAGVNFFDTANVYGWGENKGRTEEIIGSWFARGGGRREKVVLATKVYGDMSPEGEPWPNYGKLSALNIRRGVDASLKRLGTDHIDVYQFHHIDRLTPVDEIWQAVDTLVQQGKILYAASSNFPGWKIAQMNEEARRRGSFGLVSEQCLYNLAERRVEMEVIPAAEAYGLGVIPWSPLHGGMLGGILKKQAEGGRRAAGRALDRLELPGVRAQVQAYEELLDRHGLAPGETALAWLLTRPGVTGPIVGPRTVEQLDGAVRAVGLELSGELLGELDAIFPGPGASPEAFAW
>NZ_CP016559.1|WP_003957786.1|2994767_2995262_-|hypothetical-protein
MTYDISLVQVGPGEGSAREALERQVAGMGPDAELEPLRLSGQERDAWERVLLRVGREIAPVEPEEFPYSLGFWYQGPLGTVHCSYYGDSADIEVPYRYAGAEALAVMELAYRVAHVIEEECGLTGHDFEVDQPTRTGDPARAAARLGGVGGLVRREVAARGTGG
>NZ_CP016559.1|WP_003961322.1|3005866_3008680_+|hypothetical-protein
MRYGRIRDGRTPGGQAPGGQAPDGPTQDDPTWDGPTPDEPTPDGQAQGGWTQGGCRQRDGGPRGGRGRAAVRAAAGGALAVALAASLLLAPGAAPATAGTPVKPVKPVAPVLPVAPVARAGSAVLPTGDRVEPAAAPGAAAPAVRLVPLAGQEQPGRYAYTQRGGELTLRPAGLPRALPATTVNTTTGSTTTGGTPTGNAAGRGARGGPFKVGVVLTGATANGPVVQVWNRTTWAYHEVTVGTRGADGTVWLPPGDYLAVGMYGGPAADHLLARAFTVRDRALTVAMDARAARETAVTTDDSTARRAGAAVSLRLPNGEVVGFMGGRGQRVLVTPFTLKGISLRVHEVQVKKGTTANVPSPYRYELVKEFRDTVPATPRATVRTAGLARTVLTLRSPGLDTIGWLSSSRDLRGNTSSTVATPVRLPARVTEYATPGIAVRHTLDSPDGPALTTGRRLPAAGGSTGHVLGAAPFGAGACALPQSEPSELRGTRLTFAEPCAYGDGYGHQGLDRDATEDLELTSRGALVARERGRALGAPWSVTLKETGVPHTLYQTVRHTDSPRRYTRTQHSVWTFVPGGPGARPGELPLSDVRMRVSGLSDRNTAGSAPVTVHLTASSRTGRVTATPTSLEYSTDDGGTWHPLRLSGTADLTPGSGGDRRSARFTVPSGARYVSLRARAAAADGTTLTRTLLRAFGGPAPLADEQAGGIKVSHVTVNGSRTVVPAVGEGFGDADRVYDVTYTVTHPTGVAGSGVRLYRGAFDRPDAVLPTSTPHCARKSADTSVCTAYFSLDARTELGRNAFAGEWRAAAYARSAGGTSLTSRSRAGTVQILRATKLTSDGPDGKVSAGRSFTLTGTARAADWATGLPVALPGRSARLEFRARGEREYLTVGRVTTDSRGGLRISQRATRDGYWRWVLPVASGTAARTSPRVFVDVR
>NZ_CP016559.1|WP_003961321.1|3009698_3012938_-|hypothetical-protein
MSVTRTEPADPFGTARLRRGVLDAWGAGPARFREDANAEEDLVLGGYRDRLVVELAQNAADAAARTRTPGRLRLTLRPPTATSPAVLAAANTGAPLDAAGVESLSTLRASAKRDTQDSSVGRFGVGFAAVLAVSDEPAVLGRHGGVRWALAEARELTREVAAHSPGLGEELRRRDGHVPLLRLPLPAEGTAPDGYDTVVVLPLRDGAAVDLVERLLDGVDDALLLALPGLAEVVVETPESVRTLRREADGAGGTDGTAGAGQPEESGQTDGARGADTTRIHDSARGTTLWRTVNHTGTIDPDLLRDRPREERLRPYWTVTWAVPVDADGTPARPRTAPVVHAPTPTDEPLGIPALLIASLPLDTTRRHPAPGPLTDFLVRRAAEAYTELLGGWQPVTTGTIDLVPGPLGKGELDGALRAGILELLPRTAFLEPAAPRPGDTGQDEEETGLPGRERPPALRPVEAEVVEGAGTDTVRVLAEVLPSLLPAGLERRAELRTLGVARVPLTEAIDRLAGLERAPAWWRRLYDSLAGVDPDRLSGLPVPLTDGRTVIGPRQTLLPLAETPPHLTRLGLKVAHPDAAHPLLEKLGALPATPRAVLTTPQVRTAVAASLDEGETWFDDTADTLDADELAETVLTLVRDAELDPGDEPWLGALALPDEDGESVPAGELVLPGSPFAEVMREDELAFVAPALAERWGAQPLAACGVLVNFTLVRATDVVLDPDELEPRDSDYAEPDDAGLLDAVDVWCEDVLDRLPETPVPPVATEITAVRDLDLVDDDHWPQALALLARPPLRDALTQPVRVLLPDGTTETVRPYTAWWLRDHPVLDGRRPAGLRAAGGDSLLTGLYEAVDATGFDDALVLRALGVRTTVADLLDEPGGAAELLSRLADPERPVHAAQLHGLHTALADLDPEQVTLPDELRAVVDGEVCVVDAADALVVDAPDLLPLAAGRALLPVAPERAAELAELLQVRRLSGALPAPVTTEGEVHPVPDAVRVLLGPATPETYTEHDELIVDGVELEWRRTPDGTVHAATVEGVAAGLAWAAGQWPRRFEVAALLEDPSRTEELARDRWFDPLP
>NZ_CP016559.1|WP_003959003.1|3013859_3014759_-|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARAAAQETAAPGSVGEHVSLVPEGDRVVTHFFDCSEPGYRGWRWAVTVARASRAKNVTVDESVLLPGPDALLAPEWVPWSERLRPGDLGPGDLLPTAADDPRLEPGYTGEDVPPPNSVIAETSHDLAERVEAEDAELTDRTPADAAGNSRGEIAALAEELGMRRARVLSRYGLRGAADRWDEAFGERTPMAQAAPASCASCGFLVPVAGSLRQAFGICANEFAPADGRVVSLSYGCGGHSEAAVMPKPPQPAPPVLDSLAPDAFPLDDAGPDEDLGHA
>NZ_CP016559.1|WP_003959001.1|3014649_3015036_-|hypothetical-protein
MCSGGPSVPPLVGARRWAQGGERGSVRSASPATVPGRAPLRHPAEWMTVGVPGTARSGRGRRCGPPVRSACAPDLTIRQAHHMRRRRREARPCECCDDAKPYPRPSVRRGGGPGPGRGAGDGGTRERG
>NZ_CP016559.1|WP_065757125.1|3015075_3016428_+|MFS-transporter
MAAARSSHGPGALARACRAVGRALRRPFTGTARGIRRATNAQGAGESGLGRLIELHAVNGAGDVMITVALASTVFFSVPTDEARGRVTLYLAITLAPFAVLAPVIGPLLDRIPHGRRAAMAAAMLARAVLALGLSGAVATGGLELYPAALGVLVASKAYGVIRSAVVPRLLPPRISLVKANSRVTLAGLLATGTAAPIGAGLHHIGPQWPLYGACALFALDTFWALRLPPKVDSAKGEHKALMLAGPRRRPGLRTVGPSVLHGLQANVAFRMLSGFLIFFLAFLLREHPVAGQSAAVSLGVVGVAAGLGNACGTTVGAWLKARGPEAIIATVLGVALAAAVLAAVFFGAGMVAVLAAAAGLCQALAKLSLDALIQRDVPEEVRTSAFARSETLLQMAWVVGGAIGIVLPLNGVLGMTVAASIVCTGAAVSVRGLLAAARHGGGHPRPRVA
>NZ_CP016559.1|WP_003959000.1|3016569_3017046_+|hypothetical-protein
MTVAFFSGKRRRTAATIGAVSAALLTLSACEKPTPLATVTVGTESVNSEAACYNDGKAIKESLIQDCLNEKAGKTVKVALDDKIRFGVDPEIAENGWTLFIGGQPAEQEPYTKTYRSIPASAFFTSQTGQAPDKTKVSIVETSGKKLIGIWTFTLEKK
>NZ_CP016559.1|WP_009997173.1|3017122_3017869_+|futalosine-hydrolase
MRVLVVTAVAAEAEAVAAGLGAGPAPVPLSARTLAGGVGPAAAAASTARELALAAAAGTPYDLVVSAGIGGGFAPYAPVGSLVVADAIVAADLGADSPDGFLPLDELGFGRTSHRPPAALAARAAEAAGALLAPVLTVSTVTGTAARAAALSGRHPRAAAEAMEGFGVAEAATAAAVPVLEVRGISNPVGPRDRAAWRIGDALGALRTGFAGIAPVLEAAFPKAAGAPVRTAAHPAAPGHPDVDEESL
>NZ_CP016559.1|WP_003958998.1|3017865_3018705_+|1,4-dihydroxy-6-naphthoate-synthase
MTLRIAYSPCPNDTFVFDALAHGRVPGAPALDVTFADIDLTNGMAERGEGDVLKVSYAVLPWILDEYALLPCGGALGRGCGPLVLTREPGVELAGRTVAVPSERSTAYLLFRLWAAEKVPGGVGEVVVLPFHEIMPAVRDGRVDAGLVIHEARFTYQGYGLHCLADMGEHWEDVTGLPIPLGAIVARRSLGAPELRRLAESIRTSVRMAWDDPEASRPYVREHAQEMNPAVADQHIGLYVNEFTAALGEDGYAAVRGLLTRAAAEGLVPPLAPGALDFV
>NZ_CP016559.1|WP_003958997.1|3018904_3019288_-|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPDGVDSLKPGQRVEFGVVAGQRGDQALSVVVLDPTPSVAAAQRRKPDELASIVQDLTTLLENVTQQLERGRYPDKAHGAKIANMLRAVADQLDV
>NZ_CP016559.1|WP_003958996.1|3019477_3019717_+|hypothetical-protein
MTATPDAPGDGLVRVGGVVFIVGAVATLVTMAPLFLGTDPFPPIAYGVCMLMGVGFLISGVGVLRSIAAQRRTAKSLSS

Crispr_ID: NZ_CP016559_11

• CRISPR_ID: NZ_CP016559_11
• CRISPR_location: 4051319-4051390
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP016559_11

Consensus_repeat	Method
CAACCTCCCCCGGAGGGGGCACC	CRISPRCasFinder

spacers of NZ_CP016559_11

>11.1|4051342|26|NZ_CP016559|CRISPRCasFinder
CCCAAGGGGCTGGAATGTGCGCGGGC

CRISPR arrays and Neighbor proteins around NZ_CP016559_11

CRISPR arrays

The CRISPR arrays of NZ_CP016559_11

>merge|NZ_CP016559|11|4051319-4051390|CRISPRCasFinder
CAACCTCCCCCGGAGGGGGCACCCCCAAGGGGCTGGAATGTGCGCGGGCCAACCTCCCCCAGAGGGGGCACC

>NZ_CP016559|11|10|4051319-4051390|CRISPRCasFinder
CAACCTCCCCCGGAGGGGGCACC	CCCAAGGGGCTGGAATGTGCGCGGGC
CAACCTCCCCCAGAGGGGGCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003960839.1|4046495_4047608_-|hypothetical-protein	unknown	unknown	gnl|CDD|224481
NZ_CP016559.1|WP_009996496.1|4058278_4058863_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP016559.1|WP_003960836.1|4049932_4051069_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP016559.1|WP_003960831.1|4057098_4057899_+|type-III-pantothenate-kinase	unknown	unknown	gnl|CDD|237347
NZ_CP016559.1|WP_003960837.1|4049061_4049739_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP016559.1|WP_003953590.1|4039813_4040968_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213262
NZ_CP016559.1|WP_003958854.1|4060545_4060881_+|Lsr2-family-protein	unknown	unknown	gnl|CDD|378714
NZ_CP016559.1|WP_003953586.1|4042542_4043508_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270324
NZ_CP016559.1|WP_003958853.1|4060901_4061216_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003960838.1|4047752_4048949_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP016559.1|WP_003960833.1|4054118_4056107_+|L-aspartate-oxidase	unknown	unknown	gnl|CDD|236102
NZ_CP016559.1|WP_003953589.1|4041095_4041806_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224095
NZ_CP016559.1|WP_086012146.1|4043605_4045039_+|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NZ_CP016559.1|WP_003960834.1|4052919_4054122_+|pantoate--beta-alanine-ligase	unknown	unknown	gnl|CDD|376824
NZ_CP016559.1|WP_003960835.1|4052011_4052923_+|DUF2520-domain-containing-protein	unknown	unknown	gnl|CDD|227782
NZ_CP016559.1|WP_003960840.1|4045177_4046320_-|NADH-quinone-oxidoreductase-subunit-D	unknown	unknown	gnl|CDD|223722
NZ_CP016559.1|WP_003953587.1|4041805_4042543_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224095
NZ_CP016559.1|WP_003960832.1|4056103_4057099_+|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl|CDD|236125
NZ_CP016559.1|WP_003958857.1|4058873_4059056_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003958855.1|4059840_4060380_+|amino-acid-N-acetyltransferase	unknown	unknown	gnl|CDD|236132

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016559.1|WP_003960836.1|4049932_4051069_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.3e-11	38.9	0.9

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003960839.1|4046495_4047608_-|hypothetical-protein	gnl|CDD|224481	COG1565, COG1565, Uncharacterized conserved protein [Function unknown].	9.66786e-19
NZ_CP016559.1|WP_009996496.1|4058278_4058863_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	6.47946e-07
NZ_CP016559.1|WP_003960836.1|4049932_4051069_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.88687e-13
NZ_CP016559.1|WP_003960831.1|4057098_4057899_+|type-III-pantothenate-kinase	gnl|CDD|237347	PRK13318, PRK13318, type III pantothenate kinase.	5.1993e-152
NZ_CP016559.1|WP_003960837.1|4049061_4049739_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.27178e-73
NZ_CP016559.1|WP_003953590.1|4039813_4040968_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	7.72106e-145
NZ_CP016559.1|WP_003958854.1|4060545_4060881_+|Lsr2-family-protein	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	4.0403e-54
NZ_CP016559.1|WP_003953586.1|4042542_4043508_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270324	cd13606, PBP2_ProX_like, Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold. This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.18974e-85
NZ_CP016559.1|WP_003960838.1|4047752_4048949_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.99473e-47
NZ_CP016559.1|WP_003960833.1|4054118_4056107_+|L-aspartate-oxidase	gnl|CDD|236102	PRK07804, PRK07804, L-aspartate oxidase; Provisional.	0
NZ_CP016559.1|WP_003953589.1|4041095_4041806_+|ABC-transporter-permease	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	9.77887e-56
NZ_CP016559.1|WP_086012146.1|4043605_4045039_+|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	8.77486e-11
NZ_CP016559.1|WP_003960834.1|4052919_4054122_+|pantoate--beta-alanine-ligase	gnl|CDD|376824	pfam02569, Pantoate_ligase, Pantoate-beta-alanine ligase. Pantoate-beta-alanine ligase, also know as pantothenate synthase, (EC:6.3.2.1) catalyzes the formation of pantothenate from pantoate and alanine.	2.58746e-132
NZ_CP016559.1|WP_003960835.1|4052011_4052923_+|DUF2520-domain-containing-protein	gnl|CDD|227782	COG5495, COG5495, Uncharacterized conserved protein [Function unknown].	1.79041e-49
NZ_CP016559.1|WP_003960840.1|4045177_4046320_-|NADH-quinone-oxidoreductase-subunit-D	gnl|CDD|223722	COG0649, NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion].	1.93806e-146
NZ_CP016559.1|WP_003953587.1|4041805_4042543_+|ABC-transporter-permease	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.1498e-56
NZ_CP016559.1|WP_003960832.1|4056103_4057099_+|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl|CDD|236125	PRK07896, PRK07896, carboxylating nicotinate-nucleotide diphosphorylase.	1.39047e-145
NZ_CP016559.1|WP_003958855.1|4059840_4060380_+|amino-acid-N-acetyltransferase	gnl|CDD|236132	PRK07922, PRK07922, amino-acid N-acetyltransferase.	3.90115e-109

Protein sequences

>NZ_CP016559.1|WP_003960836.1|4049932_4051069_-|winged-helix-turn-helix-transcriptional-regulator
MGAVSVTIDISGLPRERIVFEISPLAELGVALHALAEPGHHPGLHGWATATSAALQPDLADRLCEADFLWRSTFSDVFMPFAALPPDPARGARGMHTLADELDLLDRFDDERFVSAALEFTCGSTYSEGGPSALSDPARRERSLELAAHRGPRQLDFTKRLLKDPAAVRAWVRRLFEDCERAFFADTWARIAPQLAADARHKTELLRHKGLAETLHAVSPALTVDEDHTCVTADKFAEGRTTAVDPDLGPGLTLVPSSFGWPHLMVLHAPGWRPVIHYPIGAPALQGPGTVELLQRRMEALAHPVRMRLCRNLARAAYTTSELAESYGITAPEVSRHLGVLKRAGLVSTRRRGRYVLHQLDVTAVARLGSDYLETVLR
>NZ_CP016559.1|WP_003960837.1|4049061_4049739_+|response-regulator-transcription-factor
MSIKVMLVDDQVLLRTGFRMVLAAQPDMEVVAEAGDGAEAIELLRSTAVDVVLMDVRMPRLDGVEATRRICAQPDPPKVLILTTFDLDEYAFSGLKAGASGFMLKDVPPGELLAAIRSVHSGDAVVAPSTTRRLLDRFSPMLPSGGPEPRNKEVDRLTEREREVMMLVAQGLSNGEIAGRLVLSEATVKTHVGRILTKLNLRDRVQVVVLAYETGLVRAGGGPAR
>NZ_CP016559.1|WP_003960838.1|4047752_4048949_+|sensor-histidine-kinase
MHRVYDFVRRHPTGSDTFWGVVLLSVALLDLSMVDRYNPGWIGVPLSVGFSIVVALRRRMPEQMLLLTAVLALVQLVAGIQTYPGDFAMLVIIYTVAAHDAARWARRLALVAGIVAAPVSQLVWPPPGDVSIAARVFLVVILVVPFVLAWVLGDSNRTRRAYFAQLEERALQLEKEREAQAKVAVAAERARIARELHDVVAHNVSVMVVQADGAAYVLDVAPDQAKKALETISTTGRQALAEMRRLLGVLRTNDGPDGDEYVPQPDVGQIEDLVEQVRKAGTTVDFRIEGTPRPLPSGVELTAYRIVQEALTNTRKHGGPQVGASVRLVYFDDGLGLLVEDDGRGASHELYEDGGADGKGHGLIGMRERVGMVGGTLDAGPRPGGGFRISALLPLKPA
>NZ_CP016559.1|WP_003960839.1|4046495_4047608_-|hypothetical-protein
MSGDDKVSAVGGTGGGAAGSGISGCGREGAGAVEVGAIGAGAVGAVGAVGAVEERGWREAAESALYGPGGFYRRPEGPAGHFRTSVHASPLFAGAVARLLRETARRLADEGRLEPSGAVSFVDMAAGRGELATGVLAALPDGFPVRAYAVERAERPAGLDPRITWTAAPPPGISGLLFANEWLDNVPVDVAEVDEDGTVRRVLVDEDGTERLGPPVTGADARWLDRWWPLARPGARAEIGRSRDAAWARAAGSVRAGLAVAVDYAHRSGDRPPFGTLTGFRSGREVRPVPDGSCDITAHVALDACALPGGTLTTQREALRALGVSGGRPPLTLAAADPAGYVRALAAAGEAAELTARGGLGDFLWLRQPR
>NZ_CP016559.1|WP_003960840.1|4045177_4046320_-|NADH-quinone-oxidoreductase-subunit-D
MTETTFGIGGAAESTDMVLNIGPQHPSTHGVLRLRLVLDGEIVRSAEPVVGYMHRGAEKLFEARDYRQIIMLANRHDWLSAFSNELGVVMAVERMLGMEVPERAVWTRTLLAELNRVLNHLMFLGSYPLELGGITPVFHAFREREELQNVMEEISGGRMHYMFNRVGGLKEDLPAGWLGRVRHTVAEVRSRMDVYDRLVLGNEIFRGRTRGVGTLSAAAAHAYGVSGPIARASGVDFDLRRDEPYLAYGELTDTLKVVTRAEGDCLARFEVLLDQTHNSLDLADACLDRIAGLAPGPVNQRLPKVLKAPEGHTYAWTENPLGINGYYLVSKGEKTPYRLKLRSASYNNIQALTELLPGTLVADMVAILGSLFFVVGDIDK
>NZ_CP016559.1|WP_086012146.1|4043605_4045039_+|hypothetical-protein
MPRGRHRHSPPLHRLLPPSAVAGVAVVCAAGSWLLTEPLLLQTLATVSAAAAVTGGVLMRRWDRSAGRRVADLTRSRAGEAWRSEERIAELETAAEEARESRLKLEAKLRAKRIELAGLRGEHAALLRRYATSETERASVLEDRRQLEADSPSPAHTHAKAGAPKALPPAPTPPRYLQAARALENLARSAAGQRRAPEQGAPGRPAPARPGALPAARPGELPPAPVRSPRPVGPGAQAPAAAPVPAPSAPVPSAAVPVPVDRPGSGAARVPAPAAEPSPAAPQGSAAVDTAIATAAPATSSVAIAEPATVTAAVAAPAIAPPAAPVPAPAAKPRAASGAGAGAPAAAAIVPYGSRRGSAQNRPEGNFDFFGNAAGGPSPERARKAIEAAVQEEDLADVVGEEALAERTAEPAATDERPVAKDPAAQESAAKDRAAKDATASAASPAREAEAGDVIDLTAHDETEKLDLEALRNAISS
>NZ_CP016559.1|WP_003953586.1|4042542_4043508_+|ABC-transporter-substrate-binding-protein
MRKTPTLAGAVLATAALTAALTACGGDSLEDSGGSPGGGSGGRGSLVVGSASFTESKVLAELYAQLLADAGYRTSVTTVKNRELYEPSLEKGEIDVVPEYAATLAEFLNAKVNGPKAPERKPVASSDANATVAALSKLAEPRGLKVLPPGKAVDQNAFAVSREFAEKNKLKTLSDLGESKLGVRIAAGDECAVRPFCAPGLKSVYGIDVTGIDPKGVGTPQSKQAVRDGVTQLVLTTTTDAALEGLVFLEDDKKLQNADNVLPVVNAKDAGDPRIASALGRLTSVLTTEDLAELNRRVDTERAKPKDVAKEYLVSRDLLKK
>NZ_CP016559.1|WP_003953587.1|4041805_4042543_+|ABC-transporter-permease
MGVLADAWTWLATGSNWSGEDGAWHRLGEHVYVSGVALAVACAVALPLACWLGHIGKGGALAVNLSNAGRAIPVFAVLALLMLTPLRTAGYTPTIIALVLFAVPPLLTNAYVGMREVDRAVVEAARGMGMSARQVFLRVELPLAYPLLMTGVRSAAVQVVATATIASMVGQGGLGRIITAGFTTFDTPQVVAGALLAALLALLVEAVLVTADRLLDPRRRATAAGRRARWTSPLPTAPGTSGRSS
>NZ_CP016559.1|WP_003953589.1|4041095_4041806_+|ABC-transporter-permease
MSAHGAVAPVRENCLTANDWICGEYLRTRAQELTDATVEHIWITGTSVLIGLLVAFPLALLARSRPAFAGPVLGLTTLLYTIPSLAMFSLLLPLLGLSAALVVTGLVLYSLTILVRNILAGLAAVPEEAREAARGLGYGPARLLWEVELPLALPALMAGVRMATVSTVALTTVGALIGRGGLGDLIDDGVQTTFKAQVLAASVLCVLLAVVADLLLLGLQRLLTPWTRIRRAEEAV
>NZ_CP016559.1|WP_003953590.1|4039813_4040968_-|ATP-binding-cassette-domain-containing-protein
MIRFEHVTKRYPDGTTAVDDLSFEVAEGELVTLVGPSGCGKTTTMKMVNRLIEPSDGRISVDGRDIAAVDPVELRRGIGYVIQQVGLFPHKTVLENTATVPHLLGWSRARARARAAELLDLVGLDPAVHGPRYPEQLSGGQRQRVGVARALAADPPVLLMDEPFGAVDPVVRDHLQSAFLRLQSQVRKTVLFVTHDIEEAVRLGDRIAVYGQGRIEQFDAPAAVLGAPATPYVADFVGADRGLKRLSVTPIEEGDLEQPPVVRLDDPLPRELGARWAVVLDAAGELHGWLSAEQARGTGTVGERARRMDAWLPLGASLKQAFSTMLQHDAGWIAVIDPEGTGRFLGVLTPARLHEALRRSIDADAHDIARADVALESIETTTPG
>NZ_CP016559.1|WP_003960835.1|4052011_4052923_+|DUF2520-domain-containing-protein
MNPTAPPDPQDRPARLTVGVVGAGRVGPALAASLALAGHRPVAASGVSDASRRRAAELLPDVPLVTPSEVLARSELVLLTVPDDALPALVEGLAETGAVRPGQLLVHTSGRFGAAVLDPATRAGALPLALHPAMTFTGTAVDVQRLAGCSFGVTAPGELRLAAEALVIEMGGEPEWITEESRPLYHAALALGANHLVTLVAQSMELLRAAGVGAPDRMLGPLLGAALDNALRSGDAALTGPVARGDAGTVAAHIAELRRHAPGAVAGYLAMARTTADRALAQGLLKPELAEDLLGVLAEDDRR
>NZ_CP016559.1|WP_003960834.1|4052919_4054122_+|pantoate--beta-alanine-ligase
MTAPHTPGATGHAPENAAPENAAPENATPTPGVDLVPDIAGLRRTLDRRAVPGRTAVVMTMGALHRGHATLIRAARDRVGPEGFVTVTVFVNPLQFGAGEDLDRYPRTLDADLALAARAGADVVFAPAATGMYPAGRPGVTVAAGPMGERLEGASRPGHFDGMLTVVAKLLQLTRPDLAFFGQKDAQQLALIRRMVHDLDFPVEIVGVETVREDDGLALSSRNRYLSAAERETALALSRALFAARDRLAAQQALTARAEAAGGTLARAAALSALGEARLAADAAAVAQAVTGCADAVRAAARAVLDEAGRATPPLELDYLALVDPADFTEVGADHQGDAILAVAARVGTTRLIDNITVGPLGIPGTPDTTDPTGTPDTTGPADPTGSQDGADSPRPGDRP
>NZ_CP016559.1|WP_003960833.1|4054118_4056107_+|L-aspartate-oxidase
MTGIRLTAPAPGWSIDADVVVVGSGVAGLTAALRCAAAGLSTVVVTKARLDDGSTRWAQGGIAAAIGEGDTPGQHRDDTLVAGAGLCAGSAVDALVTEGPGAVHRLIATGARFDLDADGDIALTREGGHHRRRIAHAGGDATGAEISRALVGAVRDAGLRTVENALVLDLITDDRGRTAGVTLHVMGEGQHDGVGAVHAPAVVLATGGMGQVFAATTNPAVSTGDGVALALRAGAEVSDLEFVQFHPTVLFLGTDSEGQQPLVSEAVRGEGAHLVDADGVRFMLGAHELAELAPRDIVAKAIMRRMREHGADHMYLDARHFGAGMWEHRFPTILAACRAHGIDPVTEPVPVAPAAHYASGGVRTDLHGRTTVPGLWACGEVACTGVHGANRLASNSLLEGLVFAERIAADIAATAHEAGTAGTAAKAHEAGTADEAGTTAKAGTAGTAGTTGTAAKAHEPATVITDATDRAPARTPAPAQPPAPVPPPAPAPAPLPLIDPAARATIQRIMSHGAGVLRSDESLRKAAAALEAVHREALEASAAPAPGAATAETPGGGGTKTAEPGVESWETANLLCVARVLTAAALAREETRGCHWREDHPDRDDTIWRRHLVVRLAPDRTLVVTPTDGTEFPAVPAVPAVPAVPAVPVVPAVPTHPREHQQ
>NZ_CP016559.1|WP_003960832.1|4056103_4057099_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MSTPDDRPFREDLPLAADGCGDSCGCAHEGDDAVECGLDPALAALLAGQGLDPVQVEDIAHVALSEDLDGGVDVTSVATVPADAVATGDFTAREAGTVAGLQIAEAVLSVIATEEFTVERHVEDGDRVEAGQKLLSVTTTTRELLTGERSALNLLCRLSGIATATRAWADTLEGTGARVRDTRKTTAGLRALEKYAVRCGGGVNHRMSLSDAALVKDNHVVAAGGVAAAFTAVREAFPELPIEVEADTLEQVREVLDAGADLILLDNFTPARTAEAVELVAGRALLESSGRLTLGNARAYAETGVDFLAVGALTHSAPILDIGLDLREADL
>NZ_CP016559.1|WP_003960831.1|4057098_4057899_+|type-III-pantothenate-kinase
MLLTIDVGNTHTVLGLFDGDEIVEHWRISTDSRRTADELAVLLQGLMGMHPLLGVELGDGIEGIAISSTVPSVLHELREVTRRYYGDVPAVLVEPGVKTGVPILTDNPKEVGADRIINAVAAVELYGGPAIVVDFGTATTFDAVSPSGAYTGGVIAPGIEISVDALGVKGAQLRKIELARPRSVIGKNTVEAMQSGIVYGFAGQVDGVVRRMKTELAPDRPEDVRVIATGGLAPMVLGESSEIDEHEPWLTLIGLRLVYERNIARM
>NZ_CP016559.1|WP_009996496.1|4058278_4058863_+|hypothetical-protein
MAFSADELRVLRRALAVAVHPGPLPDEDVRDCLRLADSVDEATREAGRLRAFLLADLDRYRSALPGSATSYLELLQDALAAGYHPLPEDLAALRSLDGGPVAAALLERCGAAGRSARVPSPAPAPRTRLLALPGGRAAADRDPAPKPKPKPRPAPEPAQPAPRPPAPGERPVPKPSEVFPPRRRPAPPPQQRAV
>NZ_CP016559.1|WP_003958857.1|4058873_4059056_+|hypothetical-protein
MDYVSALLPPVVMATFFTALIVTIVRTQGGPNKAKEDAIVDAALARAGASPAAATSADKD
>NZ_CP016559.1|WP_003958855.1|4059840_4060380_+|amino-acid-N-acetyltransferase
MSYTAPKGSVTVRRARTGDVRAVRRLVDPYVGEGILLDKATVTLYESIQEFWVAERDEDGTVVGCGALHVMWEDLAEVRTLAVDPAFTGQGIGHLLLDKLLGTARRLGVRRVFCLTFEVDFFVKHGFQEIGETSADTDVIGTDVYAELLRSYDEGVAEFLGLERVKPNTLGNSRMLLHL
>NZ_CP016559.1|WP_003958854.1|4060545_4060881_+|Lsr2-family-protein
MAQKVQVLLVDDLDGGEADETVTFALDGKTYEIDLTTANADKLRSILEPYAKNGRRTGGRASSGRGKGRAAASGNKDTAEIRAWAKANGYEVNDRGRVPATVREAYEKANG
>NZ_CP016559.1|WP_003958853.1|4060901_4061216_-|hypothetical-protein
MPPGSPLFDTLRNHSHTKSDHTTVSGRPPGQDVLPSGRAPAGTGPRRPAPGGPPSGVRPPVPGREVERDATAAECHRVRLLRMNARTHGCANAYKYAACEYSAD

Crispr_ID: NZ_CP016559_12

• CRISPR_ID: NZ_CP016559_12
• CRISPR_location: 4370833-4370910
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_12

Consensus_repeat	Method
GTGGGGGTGTCCTCCCTCGGGGAGA	CRISPRCasFinder

spacers of NZ_CP016559_12

>12.1|4370858|28|NZ_CP016559|CRISPRCasFinder
CCGAGGAGCGGAGGGCCAATTCAGCCCT

CRISPR arrays and Neighbor proteins around NZ_CP016559_12

CRISPR arrays

The CRISPR arrays of NZ_CP016559_12

>merge|NZ_CP016559|12|4370833-4370910|CRISPRCasFinder
GTGGGGGTGTCCTCCCTCGGGGAGACCGAGGAGCGGAGGGCCAATTCAGCCCTGTGGGGGTTTCCTCCCTCGGGGAGA

>NZ_CP016559|12|11|4370833-4370910|CRISPRCasFinder
GTGGGGGTGTCCTCCCTCGGGGAGA	CCGAGGAGCGGAGGGCCAATTCAGCCCT
GTGGGGGTTTCCTCCCTCGGGGAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_009996349.1|4387962_4388640_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP016559.1|WP_003960678.1|4357557_4359168_-|coenzyme-F420-0:L-glutamate-ligase	unknown	unknown	gnl|CDD|183957
NZ_CP016559.1|WP_003957147.1|4374136_4375108_+|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl|CDD|223131
NZ_CP016559.1|WP_003960671.1|4383832_4385116_+|IS30-family-transposase	unknown	unknown	gnl|CDD|225382
NZ_CP016559.1|WP_003957149.1|4377056_4377671_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003956777.1|4361567_4361831_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP016559.1|WP_003956784.1|4369274_4370642_+|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl|CDD|236557
NZ_CP016559.1|WP_003956782.1|4368697_4369222_+|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240574
NZ_CP016559.1|WP_003956778.1|4362486_4366404_+|glycosyltransferase	unknown	unknown	gnl|CDD|224137
NZ_CP016559.1|WP_009996356.1|4375436_4376894_+|adenosylhomocysteinase	unknown	unknown	gnl|CDD|377487
NZ_CP016559.1|WP_079133012.1|4385197_4386406_-|hypothetical-protein	unknown	unknown	gnl|CDD|370818
NZ_CP016559.1|WP_003956772.1|4356461_4357430_+|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl|CDD|223200
NZ_CP016559.1|WP_003956774.1|4359164_4360121_-|2-phospho-L-lactate-transferase	unknown	unknown	gnl|CDD|237443
NZ_CP016559.1|WP_003957146.1|4372865_4374029_+|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl|CDD|380414
NZ_CP016559.1|WP_003956775.1|4360125_4360683_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380416
NZ_CP016559.1|WP_003960674.1|4371268_4371451_+|hypothetical-protein	unknown	unknown	gnl|CDD|225391
NZ_CP016559.1|WP_003960676.1|4366406_4368005_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003956781.1|4368075_4368450_-|DUF3499-domain-containing-protein	unknown	unknown	gnl|CDD|378788
NZ_CP016559.1|WP_003960669.1|4386570_4387722_+|S-methyl-5-thioribose-1-phosphate-isomerase	unknown	unknown	gnl|CDD|273112
NZ_CP016559.1|WP_003960673.1|4371539_4372676_+|bifunctional-glucose-6-phosphate/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|378434

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003960678.1|4357557_4359168_-|coenzyme-F420-0:L-glutamate-ligase	gnl|CDD|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	0
NZ_CP016559.1|WP_003957147.1|4374136_4375108_+|cation-diffusion-facilitator-family-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	4.00214e-42
NZ_CP016559.1|WP_003960671.1|4383832_4385116_+|IS30-family-transposase	gnl|CDD|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.58984e-97
NZ_CP016559.1|WP_079133012.1|4385197_4386406_-|hypothetical-protein	gnl|CDD|370818	pfam10110, GPDPase_memb, Membrane domain of glycerophosphoryl diester phosphodiesterase. Members of this family comprise the membrane domain of the prokaryotic enzyme glycerophosphoryl diester phosphodiesterase.	2.65442e-05
NZ_CP016559.1|WP_003956777.1|4361567_4361831_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	3.40422e-28
NZ_CP016559.1|WP_003960673.1|4371539_4372676_+|bifunctional-glucose-6-phosphate/mannose-6-phosphate-isomerase	gnl|CDD|378434	pfam10432, bact-PGI_C, Bacterial phospho-glucose isomerase C-terminal SIS domain. This is the C-terminal SIS domain of a bacterial phospho-glucose isomerase EC:5.3.1.9 protein which is similar to eukaryote homologs to the extent that the sequence includes the cluster of threonines and serines that forms the sugar phosphate-binding site in conventional PGI. This domain contributes a good proportion of the active catalytic site residues. This PGI uses the same catalytic mechanisms for both glucose ring-opening and isomerisation for the interconversion of glucose 6-phosphate to fructose 6-phosphate. It is associated with family SIS, pfam01380.	6.07093e-20
NZ_CP016559.1|WP_003956782.1|4368697_4369222_+|metallopeptidase-family-protein	gnl|CDD|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	4.05029e-27
NZ_CP016559.1|WP_003956784.1|4369274_4370642_+|phosphomannomutase/phosphoglucomutase	gnl|CDD|236557	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed.	0
NZ_CP016559.1|WP_009996356.1|4375436_4376894_+|adenosylhomocysteinase	gnl|CDD|377487	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.	0
NZ_CP016559.1|WP_009996349.1|4387962_4388640_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.30279e-88
NZ_CP016559.1|WP_003956772.1|4356461_4357430_+|DNA-3-methyladenine-glycosylase-2-family-protein	gnl|CDD|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	5.7938e-25
NZ_CP016559.1|WP_003956774.1|4359164_4360121_-|2-phospho-L-lactate-transferase	gnl|CDD|237443	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional.	1.39494e-172
NZ_CP016559.1|WP_003957146.1|4372865_4374029_+|mannose-6-phosphate-isomerase,-class-I	gnl|CDD|380414	cd07011, cupin_PMI_type_I_N, type I phosphomannose isomerase in eukaryotes and bacteria, N-terminal cupin domain. This subfamily contains type I phosphomannose isomerase (PMI; E.C. 5.3.1.8; also known as mannose-6-phosphate isomerase) found in eukaryotes and some bacteria such as Salmonella enterica. PMI catalyzes the reversible isomerization of fructose-6-phosphate (F6P) and mannose-6-phosphate (M6P), the first committed step in the synthesis of mannosylated glycoproteins. The active site, located within the N-terminal jelly roll-like beta-barrel cupin fold, contains a single essential zinc atom and forms a deep, open cavity large enough to contain M6P or F6P. PMI type I also has a C-terminal beta-barrel fold which has diverged considerably from the N-terminal domain and is not included here. This subfamily contains an alpha helical domain that is found in eukaryotic and some prokaryotic PMIs but is not present in their archaeal counterparts. F6P is a substrate for glycolysis and gluconeogenesis, while M6P is a substrate for production of activated mannose donor guanosine 5'-diphosphate D-mannose, an important precursor of mannosylated biomolecules such as glycoproteins, bacterial exopolysaccharides and fungal cell wall components. PMI is also essential for survival, virulence and possibly pathogenicity of some bacteria and protozoan parasites, as well as for cell wall integrity of certain yeasts. Thus, PMI is a potential target against fungal infections causing serious illness or death.	6.42855e-111
NZ_CP016559.1|WP_003956775.1|4360125_4360683_-|cupin-domain-containing-protein	gnl|CDD|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.44216e-23
NZ_CP016559.1|WP_003960674.1|4371268_4371451_+|hypothetical-protein	gnl|CDD|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	1.34335e-12
NZ_CP016559.1|WP_003956781.1|4368075_4368450_-|DUF3499-domain-containing-protein	gnl|CDD|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	3.4489e-57
NZ_CP016559.1|WP_003960669.1|4386570_4387722_+|S-methyl-5-thioribose-1-phosphate-isomerase	gnl|CDD|273112	TIGR00512, methylthioribose-1-phosphate_isomerase_predicted, S-methyl-5-thioribose-1-phosphate isomerase. The delineation of this family was based in part on a discussion and neighbor-joining phylogenetic study, by Kyrpides and Woese, of archaeal and other proteins homologous to the alpha, beta, and delta subunits of eukaryotic initiation factor 2B (eIF-2B), a five-subunit molecule that catalyzes GTP recycling for eIF-2. This clade is now recognized to include the methionine salvage pathway enzyme MtnA. [Amino acid biosynthesis, Aspartate family].	1.81715e-124
NZ_CP016559.1|WP_003956778.1|4362486_4366404_+|glycosyltransferase	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	1.96604e-35

Protein sequences

>NZ_CP016559.1|WP_003956784.1|4369274_4370642_+|phosphomannomutase/phosphoglucomutase
MAADLSQIVKAYDVRGVVPDQWDEGLAELFGAAFVQVTDAGAIVIGHDMRPSSPGLAAAFARGATARGADVTLIGLCSTDQLYFASGHLGLPGAMFTASHNPAQYNGIKMCRAGAAPVGQDTGLSDIRALVERWSDEGAPEPAAEPGTVTERDTLDEYAAHLLSLVDLSGMRPLKVVVDAGNGMGGHTVPTVLAPLPLTVVPLYFELDGTFPNHEANPLDPANIVDLQQRVLAEQADLGLAFDGDADRCFVVDERGEGVSPSAITALVAARELAKHPGGTVIHNLITSWSVPEVVREMGGTPVRTRVGHSFIKEEMARSGAIFGGEHSAHYYFRDFWNADTGMLAALHVLAALGSADVPLSALVHQYDRYHGSGEINSTVDDQAARLAAVRAAFASRPGVTIDELDGLTVTSADWWFNLRPSNTEPLLRLNVETRDPATLAPLRDEVLSLVRTTA
>NZ_CP016559.1|WP_003956782.1|4368697_4369222_+|metallopeptidase-family-protein
MWRHIDPRPGPRPVSGAGGRSLRVRESYAASVMDSPPPHGPAEPRPRHRDRHGRGMRGPVTPPQVPLAASRAEAFSDLVQDSVERLERRWPQLADVDFLVMDVPYVTEDTVPLGSSAPAGRDSPARVVIYRRPVEIRAKNREERALLVHEVVVEQVAELLGLSPESVDPRYGQE
>NZ_CP016559.1|WP_003956781.1|4368075_4368450_-|DUF3499-domain-containing-protein
MSPVRRCSRTACGRPAVATLTYVYADSTAVLGPLATYAEPHCYDLCAEHSERLTAPRGWEVVRLTDASAPARPSGDDLEALANAVREAARPQGRAAEAQGGRRAADPMEVARRGHLRVLRSPES
>NZ_CP016559.1|WP_003960676.1|4366406_4368005_+|hypothetical-protein
MKRTTISLLATATALAAITAVASLTAPGAAETTAEAKAPARLPIERSSLLCPAPSGSDVAETRYTAFTPPALSGPGSRSTESGGTGEKGELGETGKAGESGGARPTAGLRPSVSGQSERRVEPGQSRPDPRAAGKPVVPLTEPGTPVSAEESAPDAPALVGTATGRLAPGWTAQQTTVVAAGATRGALGLSCTPPETDLWIPGASTAKERQDYVHLTNPDDSPAVVDIEMFGANGELRTTLTEGIPVPARAGLPILLSTLTADVAPDVTVHVSTRSGRIGAAVRVGEAETGSDWLTGAARPAATAVLPGIPADATSVRLVAYAPGAHDAELKVELAGPEGRIVPAGSESLHVKAGMTASIDLGDVTRGEPGSLIVSPEEGARATPVVAALRIVRGEGDEREIAFIPATVPVGERATVADNRAKGSTLSLTAPEKEARVRVTASAGTEGGAPVTKTYTVRARTTLAFPVPVPAGVKGSFALTVRTESGGPVHAARTLELPENGVEMFTVQPLQDDRGTVAVPKAQPDMSVLED
>NZ_CP016559.1|WP_003956778.1|4362486_4366404_+|glycosyltransferase
MSATTAAFSPAHPPEFPRHVVTAVLVAHDGARWLPDAVAGLLGQDRPVQNVIAADTGSADDSARLLTEAFGPDRVLHLARRTGFGAAVDEAVRTAPVLTPEDLPYLKRPSGWDPVTRTWQDDAYDLPDLPHGEPVQWLWLLHDDSAPEPGALTELLRVADSDADAAVLGPKLRGWYDRRQLLEAGVSIANSGRRWTGLDRREQDQGQHDQIRSVLSVSSAGMLIRRDVFERLGGFDRRLPLMRDDVDLCWRAHAAGHRVLVAPDAVLRHAEAAARERRTVDCAGRSVVNPHRVDKSGAVYTLLTNARAAALPYVLLRVVLGTVLRTLAYLVGKAPVQAVDEVMGMAAVLLRPERIVAGRRRRAAARTADTRGLRPLFPPFGATLRVTAERVAGHFGADGSTDAAGSRHGGTIGATESGPGGEDADYLEIEQFARLKKIARRPAPVLFALLFLVSLVACRGLLGSGALAGGALFAAPDGLAELWSRHADAWHPVGTGGTQTAPPYLAILATLSAFFLGSTGLALTVLLVCSVPLAGLSAYFASRPLVGSRLLRAWASVAYAFLPAVTGALATGRLGTAVLAILLPLIARAAVAAHGFGRSGRGSWRATWTYALLLTTATAFTPVVWALALVLGLGALAVRRSALKVQGPRFLAVAATPVLALAPWSFTVLTDPSALLREVGVDIGGAGASALDLLGMSPGGPKAVGGLLLIGVVLAALTALLREDRKFAIRTAWAVALVGLLFAVVTNRSTWAGPATLVYGAALLAAAVLGAELGRTRVGARSFGWRQPAAVLVALAAALGPLIGAAVWMVGGAAGPLERRDPVQVPAFVAEESGTEDQPRTLVLGGTSAAEVSYTLLRGSGGRLGDAELAAAADPDPRFDTMVANLVAGSGADQAGQLSGYAIRYVLVRDGAPREFSRVLDSTPGLNRLSQLDGSALWRVNRQVARAMIIREDGDPLPVETAEVGADTRIPAGGAGRILRIADRADEGWRATLDGRELPGKTVDGWAQGFELPAAGGRLTLSYENPTGHTVRVWAQGLLALVLIVLALPGRRVDNDDDLPEEPEAAVPPPARGADADGRRARRLRAQTPPLPADALLPADAVDLTAPVAPDGPFPAAAPGEPPYPYGYGDIPQQQQQQQQQQQQQHEHSGPQAHGQPQPQPQPQPQSHQQQHAQHRHGQPQPGGYPEPFPPQAPGPCGGEGGGYGTPGGYGGADPYGRTAHGAPESAAPQSGLPGPRAPHGGGDPAAPYEPPIPYQGYDQADPYGTAGYDRRANPDGRAGHDSDGQGAYGPYDPSGTDPHTTRGE
>NZ_CP016559.1|WP_003956777.1|4361567_4361831_+|WhiB-family-transcriptional-regulator
MTELFEQLLVEDADDEIGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRAECLEYALANDERFGIWGGLSERERRRLKKAAV
>NZ_CP016559.1|WP_003956775.1|4360125_4360683_-|cupin-domain-containing-protein
MNSDSDLQIAGDILAVQHLLQPAAEHPSTVADFVGLARSVAADRARWAPLVRYDATTRWYHRLRTGPGYEVWLLSWLPGQSSGAHDHGRSSGVLTVLRGTLTEHTRRGPHTLAAGAQRVFAPGHAHDVVNDALEPAVSLHVYFPGLTEMPMHGAAGRTADTDANVTAPQPTATTRTATDVLRLTN
>NZ_CP016559.1|WP_003956774.1|4359164_4360121_-|2-phospho-L-lactate-transferase
MRIVVLAGGIGGARFLRGLQRAAPDADVTVIGNTGDDIHLFGLKVCPDLDTVMYTLGGGINEEQGWGRQDESFKVKEELAAYGVGPEWFGLGDRDFATHIVRTQMIAAGYPLSAVTEALCARWQPGVRLLPMSDDRVETHVAVELDGERKVIHFQEYWVRLRASVAAEAVVPVGAEQAKPAPGVLEAVAAADVVLFPPSNPVVSVGTILAVPGIREAVAEAGVPVVGLSPIVGNAPVRGMADKVLAAVGVEATAAAVARHYGPGLLDGWLVDTVDTAAVAEVEAAGIRCRAVPLMMTDLAATAEMARQALALAEEVRG
>NZ_CP016559.1|WP_003960678.1|4357557_4359168_-|coenzyme-F420-0:L-glutamate-ligase
MTAFQEPVRAAAQTSVQASAQASAEASAEASAEARAQASAEARARAAVEQASGAGAPHLAEPGRPAPLDGAPPFGTPSETPSVLGGPGAAVGEGDAPSFSVRALTGFPEVRPGDDIAALIAAARPGLADGDILIVTSKIVSKAEGRVLAAADREAAIDAETVRVVARRGTLRIVENRLGLVMAAAGVDASNTPSGTVLLLPTDPDASARAIRAGLRAALGVDVGVVVTDTSGRPWRSGLTDIAIGADGVAVLDDLRGGTDAYGNPLTATIVATADELAAAGDLVKGKAAGLPVAVVRGLGRLVGDRPGDDGDEGTERGTGARALVRSAGGDLFRLGTSEAVREAVAQRRTVREFTDRPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESESSRTELLDAMRDAWIADLRRDGKSEESIAKRVRRGEVLRRAPYLVVPCLVADGSHHYGDARRDTAEREMFVVAMGAGVQNLLVALAGEGLGSAWVSSTMFCRDVVRSVLALPEHWDPMGAVAVGHAAAPPKERPGREPEAFIEVR
>NZ_CP016559.1|WP_003956772.1|4356461_4357430_+|DNA-3-methyladenine-glycosylase-2-family-protein
MSGRFQPAPRPAPAAARPVQPSAPARRWTPPGPLDLGLVLTPLRRGPADPTYRATPDGAFWRTSRTPEGPGSLRITAVGDQVEAHAWGPGAAWLLDGLPALLGADDDPGALVPRHRLVALSQRRRPGLRLTRTGLVLETLIPTILEQKVTTDEAYRAWRLLVRRHGEAAPGPTPGLFVLPDARTWSLVPSWEWHRAGVDDKRAATILRAARVAHRLEETAGLPPEQARARLELIPGIGPWTSTETVQRSHGAPDAVTVGDLHLPGIVGYALTGNRDADDTAMLDLLAPYAGQRHRAARLILLSGRVPPRRTPKMPRVHIGRL
>NZ_CP016559.1|WP_003960674.1|4371268_4371451_+|hypothetical-protein
MAIEAGLLDILACPACHAPLDDRTESETPELICTGTECGLAYPVRDEIPVLLVDEARRPA
>NZ_CP016559.1|WP_003960673.1|4371539_4372676_+|bifunctional-glucose-6-phosphate/mannose-6-phosphate-isomerase
MLDESLLDAPEALSRADRRGLLRGAAEAGARVRTAARHAAEAGIAELKPDGRPRAVLIAGSGTAAGGVADLVGALAGAGAPVTRLAPTGVAPAPGALRWALPGWAGSLDLLLVVTTDGSEPGLALLAEQAYRRGCAVVAVAPQRSPLAEAVDGHHGLVVPMATAPYELYEETPAASPGALWALFTPLLALLDRVGLLEAPPETLDKVADRLDRTAERCGPAIATYSNPAKTLAAELADSLPLIWTEGPGAAPAGRRFAAVLAELAGRPALAAELPEALPAHGVLLVSDLAAGADPDDFFRDRVEEPQALRARVVLLRDRPIDGLTAAPAARELALGHDTPISELEPEGGTELESIAELLAVTDFAAVYLALATPATPS
>NZ_CP016559.1|WP_003957146.1|4372865_4374029_+|mannose-6-phosphate-isomerase,-class-I
MDRLVNTVRPYAWGSTTAIPDLLGTAPTGEPQAEMWMGAHPGAPSRLDRGGLDEVIAADPVRELGAPAVDRFGPQLPFLFKILAAGAPLSLQVHPDLDQARAGFAAEERAGIPADAPHRNYKDANHKPELICALTPFDGLCGFRPVPVTAELLAGLGVDSLKPYADLLHAHPEEAALREVLTAVLTADPDRIAATVTEAATAADRLGGPYAPYARLAHHFPGDPGVIAAMLLNHVRLQPGEALYLGAGVPHAYLSGLGVEIMANSDNVLRCGLTPKHIDVPELLRIVRFTANDPGVLRPEASETGEEVYATPVDEFRLSRFVLAPGAAAHDLTTPGPQILLCTAGQATAGAQTLTPGASVFVPAGEPTRVSASASGSATLFRATVAH
>NZ_CP016559.1|WP_003957147.1|4374136_4375108_+|cation-diffusion-facilitator-family-transporter
MSASGGTKAIVAALAANLAIAVAKFVAFLFSGSSSMLAESVHSLADSGNQGLLLLGGRRARRAATPEHPFGYGRERYIYAFLVSIVLFSVGGMFAIYEGYEKIKHPHPIERWYWPVGVLIFAIIAESLSFRTAIKESNAVRGTLSWKEFVRRAKAPELPVVLLEDLGALVGLFLALIGVSLALATGDGLWDGIGTLCIGVLLILIALVLAAETKSLLLGESAGPEDLRKIERAIVDGDRVTRIIHMRTLHLGPEELLVAAKISVPNDDTAPEVAASINAAEERIRAACPIARVIYLEPDIYRESADAAGINPAKTPGGPNPPH
>NZ_CP016559.1|WP_009996356.1|4375436_4376894_+|adenosylhomocysteinase
MTTVTAGQDFKVADLSLAAFGRKEITLAEHEMPGLMSIRKEYAEQQPLAGARVTGSLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIAVGPNGTPEDPQGVPVFAWKGETLEEYWWCTEQALTWPNSPTGGPNMILDDGGDATLLVHKGVEFEKAGEAPDPATADSEEYGYILRLLNRTLSENPQKWTRLASEIRGVTEETTTGVHRLYEMHRDGTLLFPAINVNDAVTKSKFDNKYGCRHSLVDGINRATDVLIGGKVAVICGYGDVGKGCAESLRGQGARVIITEIDPICALQAAMDGYQVTTLDEVVGQADIFITTTGNKDIIMASDMAKMKHQAIVGNIGHFDNEIDMAGLAQIPGIVKDEVKPQVHTWTFPDGKVLIVLSEGRLLNLGNATGHPSFVMSNSFADQTLAQIELFTKPEEYPTDVYVLPKHLDEKVARLHLDSLGVKLTTLRPEQAAYIGVTVEGPYKPDHYRY
>NZ_CP016559.1|WP_003957149.1|4377056_4377671_+|hypothetical-protein
MPRGRYSLHDPHDRTPLGEERFQCAPGPSGWRYVSRVTTPSGDHAGSVDLSLDALGRPIRLSLQSLSWQIRGAALDGVTWVRTDPTGTHATEGNAPAHAFTGTSPAFLVATARLLRLTPGSPATRVRLVAFTDPVLAPRTIDQSWALVKSEAHATDNGPLTVDEYQVSALDTGEQHTVHLTGDVVLAAPGIELEDLETPPSVFP
>NZ_CP016559.1|WP_003960671.1|4383832_4385116_+|IS30-family-transposase
MDFEIRKVRTVAQGRRKLRAEREEYFRLVKAGYSCKEASALVGVNARTGREWRNGRWDPKRFRPPVSRTTAVPGQGVYTQRAPVPRERVPLPARARSRYLSERERIHIADRLREKAPIRSIAAELGRSPSTISREVRRNRTEGTRGQWHYRPFAAQARADARRPRPKPRKITHNSELRDAVQRGLDEQWSPEQICHALRRQFPDQPEMHVVHETVYQALYVQGRGHLRRELAGALRTGRARRRPHRQANCRQARFTDPMVMISDRPAEADDRAVPGHWEGDLIIGKNNGSAIGTLVERSTRYVMLLHLPADHTAASVRDALAETVRTLPPHLKRSLTWDQGSEMAGHHAFSVATDVPVYFCNPGSPWQRGSNENTNGLLRQYFPKGTDLSVHTREHLDSVAAQLNRRPRKTLDWETPAERLSKLLTA
>NZ_CP016559.1|WP_079133012.1|4385197_4386406_-|hypothetical-protein
MRWTTVNDTPGWASPGSADDRNTNPPRPAEPAGSSQWADNQPPPAPWSGQTGGHGAPTPPPAPGWGGGPHHGWGVPVAAKPGVIPLRPLGVTEILEGSVATLRGHWPTVLGITLTVSVFAQLCITAADLAFGIEPVKQSAEPGTDEALREAFDSARVALINALPTMFIGLIVTFLVTALLTMVVSRAVLGRKLSLTEAWQEARPRLPQLLGLTFLLPLIAVAIAATAMTPGLLLGGNSGALLLTLGTLVGMPLMIWVMVRFTLAPTALMLERQGVMAALRRSARLVEGAWWRTFGIMLLTILISFVIQLIVGIPFIALGYLADSGGMSDLMAGRTPDSWQFLLVTGIGAVIGYAISYPLSAGVTALLYIDQRIRRESLDLELARVADLPGSGTPSPTSGFTS
>NZ_CP016559.1|WP_003960669.1|4386570_4387722_+|S-methyl-5-thioribose-1-phosphate-isomerase
MADQYARDGVDDSPRMLPVLRWEEPPDGAVVVLLDQTRLPADEVELVCTDVPALVRAIQSLAVRGAPLLGITGAYGVALAAARGYDVEESAGLLERARPTAVNLGYGVRRALDAYRAAAGRGEAEAAAAALMAAKELHRQDAEASARMAAHGLAFLDGLFPGGGHRVLTHCNTGALVSGGEGTAFAVALSAHRAGRLRRLWVDETRPLLQGARLTAYEAARNGLPYTLLTDNAAGSLFAAGEVDAVLIGADRIAADGAVANKVGSYPLAVLAKYHRVPFVVVAPTTTIDPGTPDGASIVVEQRSADEVTELAAPVLVSAAGQDGPSFGGRRTAPLGTQAYNPAFDVTPPELVTAIVTEEGVLSPVTREGVTEVCAKARRVVSG
>NZ_CP016559.1|WP_009996349.1|4387962_4388640_+|response-regulator-transcription-factor
MKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLPGRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIIKPFKPKELVARIRARLRRSEEPAPEQLTIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLEQVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGPS

Crispr_ID: NZ_CP016559_13

• CRISPR_ID: NZ_CP016559_13
• CRISPR_location: 4680178-4680277
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas2,cas1,cas4,cas3,cas5,cas7,cas6

Consensus repeat of NZ_CP016559_13

Consensus_repeat	Method
CCGGCTGACCCGTCTGGACCTGCGGAACAAC	CRISPRCasFinder

spacers of NZ_CP016559_13

>13.1|4680209|38|NZ_CP016559|CRISPRCasFinder
GAGCTGCGCGCTGTTCCCGACGCGATCGGGCGGCTGGA

CRISPR arrays and Neighbor proteins around NZ_CP016559_13

CRISPR arrays

The CRISPR arrays of NZ_CP016559_13

>merge|NZ_CP016559|13|4680178-4680277|CRISPRCasFinder
CCGGCTGACCCGTCTGGACCTGCGGAACAACGAGCTGCGCGCTGTTCCCGACGCGATCGGGCGGCTGGACCGGCTGACCCATCTGGACCTGCGGAACAAC

>NZ_CP016559|13|12|4680178-4680277|CRISPRCasFinder
CCGGCTGACCCGTCTGGACCTGCGGAACAAC	GAGCTGCGCGCTGTTCCCGACGCGATCGGGCGGCTGGA
CCGGCTGACCCATCTGGACCTGCGGAACAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein	unknown	unknown	gnl|CDD|368264
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	gnl|CDD|366863
NZ_CP016559.1|WP_003960521.1|4677834_4678455_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380376
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NZ_CP016559.1|WP_003960523.1|4674664_4676080_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NZ_CP016559.1|WP_003960526.1|4670889_4671417_+|hypothetical-protein	unknown	unknown	gnl|CDD|235826
NZ_CP016559.1|WP_003955767.1|4689163_4690612_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003955749.1|4673517_4674684_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP016559.1|WP_003960525.1|4671419_4672634_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl|CDD|187824
NZ_CP016559.1|WP_003955752.1|4677089_4677692_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP016559.1|WP_003955751.1|4676147_4676975_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028
NZ_CP016559.1|WP_003955754.1|4678456_4679230_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235546
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl|CDD|274215
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP016559.1|WP_003955748.1|4672642_4673527_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|369792
NZ_CP016559.1|WP_003955745.1|4669654_4670893_+|hypothetical-protein	unknown	unknown	gnl|CDD|198065
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl|CDD|187853

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	1.8e-19	65.0	1.9
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	3.6e-41	135.7	0.0
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	6.2e-20	67.1	0.0
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	2.6e-87	287.5	0.0
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	4.2e-23	76.1	0.0
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	2.7e-97	320.5	0.0
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	7.5e-53	174.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein	gnl|CDD|368264	pfam05048, NosD, Periplasmic copper-binding protein (NosD). NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.	2.65019e-14
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	gnl|CDD|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.11272e-62
NZ_CP016559.1|WP_003960521.1|4677834_4678455_+|cupin-domain-containing-protein	gnl|CDD|380376	cd06121, cupin_YML079wp, Saccharomyces cerevisiae YML079wp and related proteins, cupin domain. This family includes eukaryotic, bacterial, and archaeal proteins homologous to YML079wp, a Saccharomyces cerevisiae cupin-like protein of unknown function that structurally resembles plant seed storage and ligand-binding proteins (canavalin, glycinin, auxin binding protein) as well as the bacterial RmlC epimerase. YML079wp is non-essential in yeast and localizes to the nucleus and cytoplasm. The presence of a hydrophobic ligand within a well-conserved binding pocket inside the cupin beta-barrel and sequence similarity with bacterial epimerases suggests a possible biochemical function for YML079wp and its homologs. Also included in this family are Shewanella oneidensis So0799, Agrobacterium fabrum Atu3615 and Branchiostoma belcheri Bbduf985. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold and forms a homodimer.	5.77295e-56
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	6.94624e-33
NZ_CP016559.1|WP_003960523.1|4674664_4676080_+|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.94514e-44
NZ_CP016559.1|WP_003960526.1|4670889_4671417_+|hypothetical-protein	gnl|CDD|235826	PRK06549, PRK06549, acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated.	0.00718963
NZ_CP016559.1|WP_003955749.1|4673517_4674684_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.83513e-22
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	9.11141e-48
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	gnl|CDD|187824	cd09693, Cas5_I, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.00967e-17
NZ_CP016559.1|WP_003955752.1|4677089_4677692_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	4.75122e-34
NZ_CP016559.1|WP_003960525.1|4671419_4672634_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.7512e-17
NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	9.41376e-84
NZ_CP016559.1|WP_003955754.1|4678456_4679230_+|SDR-family-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	3.42752e-78
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl|CDD|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	1.26178e-102
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.44346e-26
NZ_CP016559.1|WP_003955748.1|4672642_4673527_+|HAD-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	6.49526e-71
NZ_CP016559.1|WP_003955745.1|4669654_4670893_+|hypothetical-protein	gnl|CDD|198065	smart00997, AdoHcyase_NAD, S-adenosyl-L-homocysteine hydrolase, NAD binding domain.	1.5889e-10
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.75477e-134

Protein sequences

>NZ_CP016559.1|WP_003955754.1|4678456_4679230_+|SDR-family-oxidoreductase
MTRSDLPDLTGQTVLVTGASGGIGSAVARRFADAGAAVVVHGHHGREQAERLAAELTARECRAVALTADLTDEAACRRLVADSAAWSGRLTGLVNCAGVQPVRQLAEMTTAEWRQVVDTNLAGAFTCTQAAVPVLAAHGGGSVTHIASIEGSHPAFQHAHYCASKAALIMHARSAALEYGPLGVRVNTVSPGLIDRPGLDGEWPEGVRRWKQAAPLGRLGTGQDVGNACVFLASGLASWITGHDLVVDGGVSSAPTW
>NZ_CP016559.1|WP_003960521.1|4677834_4678455_+|cupin-domain-containing-protein
MTGKTGKTGNTGKEAMRAPRPTVADLTALYGLEPMPLEGGRFRRTWAGPPGPDGHPVGSAIVVLLSTEDDQFSAMHRLPTDEVWHFYLGDPVELLLLEADGTSRVVVLGPDVLGGQLVQFTVTAGTWMGGGVAAGGEWALFGCTMAPGFSSEDYEGGDAGALAARYPEVAGRIEALCRPGVPLRHPAGSEGALDGPGGSSATGSEG
>NZ_CP016559.1|WP_003955752.1|4677089_4677692_+|histidine-phosphatase-family-protein
MKIYLVRHGQSQWQVSPSEDWDTSLSPLGHEQAGHLGKWFAEGAPLDGTSRLSVGSVVTSPLKRARETAGHLCDSLGVTAGVQPTLKEAAFHVVSELPKASAPFAPWPAEPLSERYRDFRAQARTALEELTRRAEETGQPVLAVTHGGLIKTVVRTIAESDTFCLKLYNCGINEIEWANGRWRVVHINLWDHLPPALRTT
>NZ_CP016559.1|WP_003955751.1|4676147_4676975_+|hypothetical-protein
MISPKMPQNESVYSRSGDSVVFNQLALKIEMDEVSNEDYYRWLDDMIATIGERVPGAKIVEKEGARQTPPLNTAIYYDTEDFRILHTGALLRTSCNKITHAFCAFKAAQDENHVRRDHRHVFDGEEKATIQAAPSSPEAVAVVQRLMARTDIQHPGTFLEESYGIPRTELIPTVKLDDLRYTFFVWLDKRDALRCSIDRATVSNLRLPEAERVERPVSEVELAIYPRIEPEIAQDPRVVELIKVLSEDLCARFDTRVTSDIKYQRSATALGMGGR
>NZ_CP016559.1|WP_003960523.1|4674664_4676080_+|cation:proton-antiporter
MSLETAEVAHVLLALIALLVAAHLGGYLFARMRQPQVIGEILGGLMLGPTVLGEIAPDAQRWLLPTDGATGHVLGAFYQIGLLLLVYLTGTELRASRQEKGQRAIGFITVSGLVLPFGFGLAIASVADTEDLIGPNGSPTTLALVFGMAVAVTSVPVISRIMMDLGILQSLFARIVLAVAVIEDILLYVILAVVLGVAQANADETYGLWAWLDVDSLPVAIGYFSVVPLVFLGLLLWLGPRSFSGLTASRANVVEQRSPLAFRLVVVFLLCAACTGLGIDPIFGALVAGMCTAGDTGKRAKESQETLRHVSMGLFVPIYFAIVGVKLDLIRNFDPLFFLWFFVLACLVKTFSVWLGARAAGESHPAAMNLAVAMNARGGPGIVLASVAFGAHIINESFFTSLVLLSIISSQIAGAWLGRVVAQGKPLMPPAAGAPAPDSAPDSDSSTSTSTSTSTSEDAASARAGTRNTGR
>NZ_CP016559.1|WP_003955749.1|4673517_4674684_+|Gfo/Idh/MocA-family-oxidoreductase
MDIAIVGTGRDSGVHARWISECPAFSVTAVACDRAAEAEAEAGTDGFGTGTGEAGTVGSGRSGSGTAGSGAVGTGAGAVLDAVRTYHPHAEPAADALALIRHGRIDAVALTGPADGHGLGPARDTLVSEALARGLLVMCEAPLARDRSTALRLAEEAHTRAARAHVALPLRENPALRHARKALAEGAIGDLLTLDVELHDGAAGPDRTAPGRRAAGVLVERGTHALDLVPWLTGTDLWEVASAWTHRVQDTPYPARETDRPDRGGDDIAQAELRTVVRPARARVTVSRTPAPRPQLLVTVRGDRGVLHTRVDTADGSGLLTLATGAREAQQVFGAHPMNPYRRLADDPHARVGLTPGFDDGLAALTLVDAVLTASGTERRQGSVPGNR
>NZ_CP016559.1|WP_003955748.1|4672642_4673527_+|HAD-family-hydrolase
MIVSDLDGTLLDSRGGISERTRAAVRAAHRAGHVFVLASARPVRDVRPIAEALGHRAIAVCSNGAVSYDYARDTVVDHHPMEQADAMGVITALRRRFPGVRLGCERWPDLLLEDGFALDPALSPEARRVRALEEEIDGRGLGKLIVQTEGSAHDYYRVAADALPPGLATVTVSTPAFCEITRRGVTKAMALDLLAGRLSIPVERVVAFGDMPNDLPMLRWAGRSVAMANAHPDVLAAADETTLSNDEDGVAHRLEALLAEASDCAPGSPAPLPPPSPRTTAHRTAQRDKEHPWT
>NZ_CP016559.1|WP_003960525.1|4671419_4672634_+|MFS-transporter
MLAAYRSCLSPQHSKYLLISNLLGRLPNGMAPLAIALFLRSQGLGFGTVGAVTALYGLSMAVGGPLLGRAVDRFGQVRVLPVSAGISAVGFLALVGAGDGSVAAASAAAVLAGLFSPPLEPCLRTLWPSVLKDPRDISAAYALDASLQEVVFVAGPLLVVGLTSVADPSVALVVTTVAMLVGTLAYIVPEPVRHWRAEPRTPDWAGPLRSVRLRQLLVSLAFVGAGLGALNIATVAYQEHVGSDGLSGILLGVNAAGALIGGLYYGAREWRADTSQRLTVLLLGMFLCNLPLVLVPHPIVVGVLVFCSGLFLAPALTCGFAIIGEVAPQGTVTEAFAWMVTAVLAGNALGSSTAGTAEQQVGIWASFLVLVVAGAVAFATAALFRRGRSGFGGPTALSGKQAAS
>NZ_CP016559.1|WP_003960526.1|4670889_4671417_+|hypothetical-protein
MTRPTPRPGVDWDAARRRLLVGYGAAGDHPRQEEVSVPARVVLDGQGGAVDVDIMALPDRVADALARYAVSVRRSPQDGIALDTDAGWLWLHLADGVPAEQLRGTAHVRITLDGSRIAEVELTLSPTAEAEPAPPPTTGTGPIPRPATGAGPLSRPPGAGPAPDPTTAPMPGDRR
>NZ_CP016559.1|WP_003955745.1|4669654_4670893_+|hypothetical-protein
MTQSPASETALYLRRPATPGKPSRATRATSARTRSAVGPGPRTGRPRLPALRKVVESFPADGVSLVVTGDVAPGTVAYLRVLADALDVSAVITPPGPGGAECAAHLGGALVLTPDHPQDLVRTVAEYTGRLTRRTSVPVVVQGPGCLLSDEGSGLLAEQGARGAVWSAQCGVPRRTTEPSRLRLPVFTTAGSALDPLIDAPAGHAIAQTLEHRLRHDLARSLSECTVAVLGFGGRHAAVAAALRALGAEVSVCDRDSLAACAAVLAGYRVTDRAELLGGADVVVDLQGDLPPDRDALRLLKAGAVVVTEGFHPPDQHPDGTFGALTRVERNEGLAVCRFQDKPLYLLTGCAPSHVDERIVGRLHDLLCCELYLCVRELARGPRPPGVRGLSREQCEEIAWIWCETYGRSPWS
>NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase
MDQTGIAPDESLPLSQRLLGRIRDVPDFPQEGIVFKDITPLLADPGAFSDLVDALADLAVRQGATAVAGLEARGFILAAPVALKAGLGFVPVRKAGKLPGPTLAQSYALEYGTAEIEVQRDAFAPGSRVLVVDDVLATGGTLEASIRLIRDAGAQVVAVGLLMELGFLGGRDRLHPTLDGVPMEAVITL
>NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein
MIRFSRTLSSPWSAAAVGAAVLFGVAAPAPAAHAAPLACGQTVTVSVVLSANLLNCPGDGLIVGGNGITIDLNGRTVDGVGLGVGIRNNGFDNVTVTNSGSTPARVQEFDHGVQLNAGTLGNIVEKLTVQNNEFSGIGLNNAHSDNRVRNNHIDRQAHRGVEITAGSSGNLIADNRITGNQGGGVFAQNAVGNRVERNQISGSGGAGLALEGSRTNTLLANTVGTSSDGAIVLRLGSDGNLVQGNSSSGSADAGLTVSGSAGNRILSNTLHGSGDSGIVLDSAHGSTVTGNDVSRNTGGIELSFANNNTIESNIASNTTGDGISLNGSLNNQLRLNKAENNGSSGIYVVGDAAAGSGNQLVGNIANANKGSGIFVSKAVHTLQGNTARGNNSWGISADRGNVDGGANRAGGNAQSGQCTGVVCAP
>NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2
MFVILIYDTAVERNPRVLKTCRKYLHWTQRSVFQGELSAAQYRALMAALSGAIDPGYDSIRTYTVRSPEMVETDTLGVDLGGPGDII
>NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MPAVGRTYWLTEPCRIRREDNSVRVERQDGSPVRIPITDIRDLVVFDHVDVNTSALSLLSRSGVTLHVLDHYGNHAGHFSPAESMASAAVVRRQVEITADEEQRLAIGRSLVLASAQNLRWSLDTDLLDPALDSLNAALPGCGSSEAIMGEEGNFRRTAWAVLDQRLPPWLRLNGRTRRPPTNAGNAFISYLNSIVYARVLTALRSTPLHPAIGFLHADTDRRRNTLALDLAEPFKPLFAERLLRRTAHQKHLKQNDFETDVGRASLSKDGRKKIAALVREELATTVYHRSLKRKVSYEELIHLEALKIVRLCLEGQPYKPFRPWW
>NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein
MSPSADPLSDGAAPVGGVHITYLVHCPRQLWLYARGYRPEQRSDLVAFGEVVNETTFPRRRDVDLGEAKIDWVTTGAVVHETKSSRAPAPAHSAQVRHYCLLLERRGVNVRGGVVHYPLVRRTVDVLWDDDARTRAEDAEADAQAVIAAATAPERLTRDQCRGCSYLDYCWGD
>NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3
MTNPPPRASLNDVRAKSTPAEDRERLTTHSRTVHAAVGLIEDRIANAGVLADSPAFWSQVRRAALLHDAGKIAEGFQRQVEPRGIPWGERHEVLSLAYADLLAGAAAWSEDDLTMVATLVATHHRALHNDGGTGHGGKPALSRIYNKETDWEEAFGTSVEDVDGRPVVQVPRFLHRELLAWFCGFLAVDPPSTRPGDPSLAQRARHLLQRLLDTWHHPVRPHRGLLAVLAQGALTLADRSGSAHIGLQTHMPLPYDYLARLPYHPHSHQRQAAETLGHLTLVAPTGSGKTEAGLAWAATQIGTMPGRPRVVWTLPYRASLNAIRRRLSEDLIPVPGERKADIGLLHGTVAQTLLADGLDDDCPGREPNTPPTADQARKARAQAGAMRLFTQRVRVATPHQLLSGAIAGPAYSSVLLEQANCVFVLDELHAYEPRTFGRLCAAMRLWERLGSRFAVLSATLAEVMIRIIEESVEQPVTVHRSPEGSGPVRHRLTLDELPIDAPESVQRIRDWLNEGHSVLAVVNTVARAQELFGQLADDARAARPGDPHAALLLHSRFRNGDRDTIERALLRRHPERRPGDGALRGGLVVATQAVEVSLQLDFDRAAVECAPVEAVAQRAGRVNRRGLHPDGPVEFRVHRVDGPRPYDPDAMDAAWAALRGLVADGATALSEQDIDELLRRAYATEWGKGWEEQARAARDAFAARFLTFTDPFHDRSEFARELSEAFDSTEVLHHDDAEEYRALTRGKAGDPLLASRLLIPLRLGQLRQFDCSFDPYLKVNMTDSAYDPTLGLQPPAARETIL
>NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5
MTGGPRPGARPPTGVPVTEPLSAWRVVFYAPVASFRDPLFPGLTRGLPVPPPSTVRGLLAAATGEPSESLAFGMAAWSEGGGTDDETYHPISASGLNPSVAGRVRPGKGGMTIRSRPFLTGVHLTVWLPGPDGARIADALRRPRWPLRLGRSQDLVHVGERTRVTLNPAEEAAVGSALAPLSGHDVPSATVHRLAASVSTDRMASRWTDYLWCDIPAGRHPVRGAYEDATCRAHPGAEKGQALWLLEP
>NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MAYLAGRMLVSVEAGAPNNGRSADTTARVKYATVRGRRHPYVSAQAVRRWIRDGMVRQGVPASPVTRVGKAQQRAQKANTDADPITYPDDDLFGYMRAGAKKDDDATTLRDSPFMLGTLLSVTPAHPTEDFGVMARGVSEPVLHGHEFYSADLAAPFLLDLPRIGTFTLPNAHGVGRPNYLSQEAALQVARAAALGAGAESFRGQDSVRLPVAERRRRAALLLESIAHLHGGAKQALHYGDRVPHVIVLVPFHGGVNPLTHVITGDEEGLRIRGDVLRGELEAWAGEWEAPVRIGWRPGFRDDLRERFEKECAAEIADRTVVIGHPRTILLELAAEMRDGTTLDHWFEDPVREPVREPVR
>NZ_CP016559.1|WP_003955767.1|4689163_4690612_-|hypothetical-protein
MTAPHPAPTPDPAPLALTGHPLQRAGAWAVTVMAGRKHPEEVSADDLNQVMETVLTDAAGAGAAAKTDSSYDWWKVLFALYPNAKVTHAGRPRDAAALRGALTPMFAPDGTGPGQLPCTFCGTPATAVWAKSMLPLFDSNTALNTLPPGVPGWPVCRGCRIAMWALPYGSWVTAGSATVLSCETTAAEREFALRNVRRAQRIVHAGFEGSAAGVRPELVTLRALRAVGSELSATTLWSFKNDNQEPWLRVTRTRRAVPRFLAAVEGNAALRRGWRLLELALTQRDTDGRVTAQGSVEAARLLFEPEDGRGRYLPSQLHQLLSDTERWPLRDRTALTRLALHYEKEVYGMAPDLEGVATLIVDWIEHGSGSPRGRLAEYKSAGLSDYRLGLLLHQACFRLSFDGRRPVTGPDDWRPFLEKRPRAWEHRMLLTAEVFRLLHQRGIAVGDPPEDPKEREQVERQVNQPLLDTTPEPGYDDYFGGA
>NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6
MRIRVDVATDAPHLTWADVHGPARAVVYRLLEEHDPAIARSLHDDGWRGHPLKPIGVTSPQFKGAPQKNGVYTTSPHGAIWFGSPVPEIAAALVTALARRTEIVWGNARLRVRGFSIEVAAPAPVEGLVELETATPVVVRHERRELLPGDEHYIERLAHNLTHKADVLGLPAPRSLRLLKAGPRRRFSVRGAPRIGAQVRVSMEADPRFVDAIRSWGLGLDTVQGFGWIR

Crispr_ID: NZ_CP016559_14

• CRISPR_ID: NZ_CP016559_14
• CRISPR_location: 4682591-4683076
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas2,cas1,cas4,cas3,cas5,cas7,cas6

Consensus repeat of NZ_CP016559_14

Consensus_repeat	Method
GTTGCGAACCCACCAGGGCTGATGACGAC	CRISPRCasFinder
GTTGCGAACCCACCAGGGCTGATGACGAC	CRT
GTTGCGAACCCACCAGGGCTGATGACGAC	PILER-CR

spacers of NZ_CP016559_14

>14.1|4682620|40|NZ_CP016559|CRISPRCasFinder,CRT
GCGCGCACTGGCTCGGCCAGCCCCTGGCCGTCGTCGGCGA
>14.2|4682689|35|NZ_CP016559|CRISPRCasFinder,CRT,PILER-CR
TGGGGAGGGCCCCGGGAAGGGGCGGGGGAGGGGTC
>14.3|4682753|38|NZ_CP016559|CRISPRCasFinder,CRT,PILER-CR
ACCCAGGCCCTCGGCCTCCACGTCCAGCTCACCCACCG
>14.4|4682820|35|NZ_CP016559|CRISPRCasFinder,CRT,PILER-CR
CTTGACGGGCGACGCCATCCCATGGCGTTCACCCT
>14.5|4682884|35|NZ_CP016559|CRISPRCasFinder,CRT,PILER-CR
GCGCGCGCTCTCGGCTACCCCGCTGCCCGGATCAC
>14.6|4682948|35|NZ_CP016559|CRISPRCasFinder,CRT,PILER-CR
CTCCACGTCTCCGCAGAAGGCGACTGGGCCATCTC
>14.7|4683012|36|NZ_CP016559|CRISPRCasFinder,CRT,PILER-CR
CACACTGCGCCAGGACGCTCCCGACTCGGCGTGGGT

CRISPR arrays and Neighbor proteins around NZ_CP016559_14

CRISPR arrays

The CRISPR arrays of NZ_CP016559_14

>merge|NZ_CP016559|14|4682591-4683076|CRISPRCasFinder,CRT,PILER-CR
GGTGGGAGCCTGCGGGGGCTGATGACGACGCGCGCACTGGCTCGGCCAGCCCCTGGCCGTCGTCGGCGAGTTGCGAACCCACCAGGGTTGATGACGACTGGGGAGGGCCCCGGGAAGGGGCGGGGGAGGGGTCGTTGCGAACCCACCAGGGCTGATGACGACACCCAGGCCCTCGGCCTCCACGTCCAGCTCACCCACCGGTTGCGAACCCACCAGGGCTGATGACGACCTTGACGGGCGACGCCATCCCATGGCGTTCACCCTGTTGCGAACCCACCAGGGCTGATGACGACGCGCGCGCTCTCGGCTACCCCGCTGCCCGGATCACGTTGCGAACCCACCAGGGCTGATGACGACCTCCACGTCTCCGCAGAAGGCGACTGGGCCATCTCGTTGCGAACCTACCAGGGCTGATGACGACCACACTGCGCCAGGACGCTCCCGACTCGGCGTGGGTGTTGCGAACCCACCAGGGCTGATGACGAC

>NZ_CP016559|14|13|4682591-4683076|CRISPRCasFinder
GGTGGGAGCCTGCGGGGGCTGATGACGAC	GCGCGCACTGGCTCGGCCAGCCCCTGGCCGTCGTCGGCGA
GTTGCGAACCCACCAGGGTTGATGACGAC	TGGGGAGGGCCCCGGGAAGGGGCGGGGGAGGGGTC
GTTGCGAACCCACCAGGGCTGATGACGAC	ACCCAGGCCCTCGGCCTCCACGTCCAGCTCACCCACCG
GTTGCGAACCCACCAGGGCTGATGACGAC	CTTGACGGGCGACGCCATCCCATGGCGTTCACCCT
GTTGCGAACCCACCAGGGCTGATGACGAC	GCGCGCGCTCTCGGCTACCCCGCTGCCCGGATCAC
GTTGCGAACCCACCAGGGCTGATGACGAC	CTCCACGTCTCCGCAGAAGGCGACTGGGCCATCTC
GTTGCGAACCTACCAGGGCTGATGACGAC	CACACTGCGCCAGGACGCTCCCGACTCGGCGTGGGT
GTTGCGAACCCACCAGGGCTGATGACGAC

>NZ_CP016559|14|2|4682591-4683076|CRT
GGTGGGAGCCTGCGGGGGCTGATGACGAC	GCGCGCACTGGCTCGGCCAGCCCCTGGCCGTCGTCGGCGA
GTTGCGAACCCACCAGGGTTGATGACGAC	TGGGGAGGGCCCCGGGAAGGGGCGGGGGAGGGGTC
GTTGCGAACCCACCAGGGCTGATGACGAC	ACCCAGGCCCTCGGCCTCCACGTCCAGCTCACCCACCG
GTTGCGAACCCACCAGGGCTGATGACGAC	CTTGACGGGCGACGCCATCCCATGGCGTTCACCCT
GTTGCGAACCCACCAGGGCTGATGACGAC	GCGCGCGCTCTCGGCTACCCCGCTGCCCGGATCAC
GTTGCGAACCCACCAGGGCTGATGACGAC	CTCCACGTCTCCGCAGAAGGCGACTGGGCCATCTC
GTTGCGAACCTACCAGGGCTGATGACGAC	CACACTGCGCCAGGACGCTCCCGACTCGGCGTGGGT
GTTGCGAACCCACCAGGGCTGATGACGAC

>NZ_CP016559|14|1|4682660-4683076|PILER-CR
GTTGCGAACCCACCAGGGTTGATGACGAC	TGGGGAGGGCCCCGGGAAGGGGCGGGGGAGGGGTC
GTTGCGAACCCACCAGGGCTGATGACGAC	ACCCAGGCCCTCGGCCTCCACGTCCAGCTCACCCACCG
GTTGCGAACCCACCAGGGCTGATGACGAC	CTTGACGGGCGACGCCATCCCATGGCGTTCACCCT
GTTGCGAACCCACCAGGGCTGATGACGAC	GCGCGCGCTCTCGGCTACCCCGCTGCCCGGATCAC
GTTGCGAACCCACCAGGGCTGATGACGAC	CTCCACGTCTCCGCAGAAGGCGACTGGGCCATCTC
GTTGCGAACCTACCAGGGCTGATGACGAC	CACACTGCGCCAGGACGCTCCCGACTCGGCGTGGGT
GTTGCGAACCCACCAGGGCTGATGACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003955755.1|4679230_4680418_+|hypothetical-protein	unknown	unknown	gnl|CDD|275380
NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein	unknown	unknown	gnl|CDD|368264
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	gnl|CDD|366863
NZ_CP016559.1|WP_029182926.1|4693111_4694719_+|ATP-binding-protein	unknown	unknown	gnl|CDD|366045
NZ_CP016559.1|WP_003960521.1|4677834_4678455_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380376
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NZ_CP016559.1|WP_003960523.1|4674664_4676080_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NZ_CP016559.1|WP_003955767.1|4689163_4690612_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003955749.1|4673517_4674684_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl|CDD|187824
NZ_CP016559.1|WP_003955752.1|4677089_4677692_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP016559.1|WP_003955751.1|4676147_4676975_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028
NZ_CP016559.1|WP_003955754.1|4678456_4679230_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235546
NZ_CP016559.1|WP_065757163.1|4694715_4696878_+|ATP-binding-protein	unknown	unknown	gnl|CDD|206743
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl|CDD|274215
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP016559.1|WP_003955748.1|4672642_4673527_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|369792
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl|CDD|187853

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	1.8e-19	65.0	1.9
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	3.6e-41	135.7	0.0
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	6.2e-20	67.1	0.0
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	2.6e-87	287.5	0.0
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	4.2e-23	76.1	0.0
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	2.7e-97	320.5	0.0
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	7.5e-53	174.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003955755.1|4679230_4680418_+|hypothetical-protein	gnl|CDD|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	1.66064e-48
NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein	gnl|CDD|368264	pfam05048, NosD, Periplasmic copper-binding protein (NosD). NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.	2.65019e-14
NZ_CP016559.1|WP_065757163.1|4694715_4696878_+|ATP-binding-protein	gnl|CDD|206743	cd11383, YfjP, YfjP GTPase. The Era (E. coli Ras-like protein)-like YfjP subfamily includes several uncharacterized bacterial GTPases that are similar to Era. They generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain.	7.17954e-37
NZ_CP016559.1|WP_029182926.1|4693111_4694719_+|ATP-binding-protein	gnl|CDD|366045	pfam00350, Dynamin_N, Dynamin family.	2.09161e-07
NZ_CP016559.1|WP_003960521.1|4677834_4678455_+|cupin-domain-containing-protein	gnl|CDD|380376	cd06121, cupin_YML079wp, Saccharomyces cerevisiae YML079wp and related proteins, cupin domain. This family includes eukaryotic, bacterial, and archaeal proteins homologous to YML079wp, a Saccharomyces cerevisiae cupin-like protein of unknown function that structurally resembles plant seed storage and ligand-binding proteins (canavalin, glycinin, auxin binding protein) as well as the bacterial RmlC epimerase. YML079wp is non-essential in yeast and localizes to the nucleus and cytoplasm. The presence of a hydrophobic ligand within a well-conserved binding pocket inside the cupin beta-barrel and sequence similarity with bacterial epimerases suggests a possible biochemical function for YML079wp and its homologs. Also included in this family are Shewanella oneidensis So0799, Agrobacterium fabrum Atu3615 and Branchiostoma belcheri Bbduf985. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold and forms a homodimer.	5.77295e-56
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	6.94624e-33
NZ_CP016559.1|WP_003960523.1|4674664_4676080_+|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.94514e-44
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.75477e-134
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	9.11141e-48
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	gnl|CDD|187824	cd09693, Cas5_I, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.00967e-17
NZ_CP016559.1|WP_003955752.1|4677089_4677692_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	4.75122e-34
NZ_CP016559.1|WP_003955749.1|4673517_4674684_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.83513e-22
NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	9.41376e-84
NZ_CP016559.1|WP_003955754.1|4678456_4679230_+|SDR-family-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	3.42752e-78
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl|CDD|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	1.26178e-102
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.44346e-26
NZ_CP016559.1|WP_003955748.1|4672642_4673527_+|HAD-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	6.49526e-71
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	gnl|CDD|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.11272e-62

Protein sequences

>NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein
MIRFSRTLSSPWSAAAVGAAVLFGVAAPAPAAHAAPLACGQTVTVSVVLSANLLNCPGDGLIVGGNGITIDLNGRTVDGVGLGVGIRNNGFDNVTVTNSGSTPARVQEFDHGVQLNAGTLGNIVEKLTVQNNEFSGIGLNNAHSDNRVRNNHIDRQAHRGVEITAGSSGNLIADNRITGNQGGGVFAQNAVGNRVERNQISGSGGAGLALEGSRTNTLLANTVGTSSDGAIVLRLGSDGNLVQGNSSSGSADAGLTVSGSAGNRILSNTLHGSGDSGIVLDSAHGSTVTGNDVSRNTGGIELSFANNNTIESNIASNTTGDGISLNGSLNNQLRLNKAENNGSSGIYVVGDAAAGSGNQLVGNIANANKGSGIFVSKAVHTLQGNTARGNNSWGISADRGNVDGGANRAGGNAQSGQCTGVVCAP
>NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase
MDQTGIAPDESLPLSQRLLGRIRDVPDFPQEGIVFKDITPLLADPGAFSDLVDALADLAVRQGATAVAGLEARGFILAAPVALKAGLGFVPVRKAGKLPGPTLAQSYALEYGTAEIEVQRDAFAPGSRVLVVDDVLATGGTLEASIRLIRDAGAQVVAVGLLMELGFLGGRDRLHPTLDGVPMEAVITL
>NZ_CP016559.1|WP_003955755.1|4679230_4680418_+|hypothetical-protein
MMACSAAPTQRGFTDVHGGTVRRFLSGAGTSSTSRGAVFVTDHGLSSCTWTSVTDDMTGKVVSLSAREQGMRSLPEALPEIARLEDLAALDLSFNLLDDLPADLGRLHRLTELRLDSNQFSRFPDAVLGLTGLQVLSLYRNGLSNVPSGLGGLREIRVLNLAGNRLSSVPAEIGALSRLHTLDLGHNELTDIPPSLGDVTGLSRYLYLSDNKITSVPDSLCRLGHLRYLNITDNRLTALPERFGDLASLRELRLYHNRLTGLPRSIGALRELREAHLMGNRLTGLPEEIGGLADLRELRLMDNRVTALPDTIGGLVRLTRLDLRNNELRAVPDAIGRLDRLTHLDLRNNRLHELPPTLAALPRLEKLDLRWNPLALDPLPAWVSSLEQRGCVVLT
>NZ_CP016559.1|WP_003955754.1|4678456_4679230_+|SDR-family-oxidoreductase
MTRSDLPDLTGQTVLVTGASGGIGSAVARRFADAGAAVVVHGHHGREQAERLAAELTARECRAVALTADLTDEAACRRLVADSAAWSGRLTGLVNCAGVQPVRQLAEMTTAEWRQVVDTNLAGAFTCTQAAVPVLAAHGGGSVTHIASIEGSHPAFQHAHYCASKAALIMHARSAALEYGPLGVRVNTVSPGLIDRPGLDGEWPEGVRRWKQAAPLGRLGTGQDVGNACVFLASGLASWITGHDLVVDGGVSSAPTW
>NZ_CP016559.1|WP_003960521.1|4677834_4678455_+|cupin-domain-containing-protein
MTGKTGKTGNTGKEAMRAPRPTVADLTALYGLEPMPLEGGRFRRTWAGPPGPDGHPVGSAIVVLLSTEDDQFSAMHRLPTDEVWHFYLGDPVELLLLEADGTSRVVVLGPDVLGGQLVQFTVTAGTWMGGGVAAGGEWALFGCTMAPGFSSEDYEGGDAGALAARYPEVAGRIEALCRPGVPLRHPAGSEGALDGPGGSSATGSEG
>NZ_CP016559.1|WP_003955752.1|4677089_4677692_+|histidine-phosphatase-family-protein
MKIYLVRHGQSQWQVSPSEDWDTSLSPLGHEQAGHLGKWFAEGAPLDGTSRLSVGSVVTSPLKRARETAGHLCDSLGVTAGVQPTLKEAAFHVVSELPKASAPFAPWPAEPLSERYRDFRAQARTALEELTRRAEETGQPVLAVTHGGLIKTVVRTIAESDTFCLKLYNCGINEIEWANGRWRVVHINLWDHLPPALRTT
>NZ_CP016559.1|WP_003955751.1|4676147_4676975_+|hypothetical-protein
MISPKMPQNESVYSRSGDSVVFNQLALKIEMDEVSNEDYYRWLDDMIATIGERVPGAKIVEKEGARQTPPLNTAIYYDTEDFRILHTGALLRTSCNKITHAFCAFKAAQDENHVRRDHRHVFDGEEKATIQAAPSSPEAVAVVQRLMARTDIQHPGTFLEESYGIPRTELIPTVKLDDLRYTFFVWLDKRDALRCSIDRATVSNLRLPEAERVERPVSEVELAIYPRIEPEIAQDPRVVELIKVLSEDLCARFDTRVTSDIKYQRSATALGMGGR
>NZ_CP016559.1|WP_003960523.1|4674664_4676080_+|cation:proton-antiporter
MSLETAEVAHVLLALIALLVAAHLGGYLFARMRQPQVIGEILGGLMLGPTVLGEIAPDAQRWLLPTDGATGHVLGAFYQIGLLLLVYLTGTELRASRQEKGQRAIGFITVSGLVLPFGFGLAIASVADTEDLIGPNGSPTTLALVFGMAVAVTSVPVISRIMMDLGILQSLFARIVLAVAVIEDILLYVILAVVLGVAQANADETYGLWAWLDVDSLPVAIGYFSVVPLVFLGLLLWLGPRSFSGLTASRANVVEQRSPLAFRLVVVFLLCAACTGLGIDPIFGALVAGMCTAGDTGKRAKESQETLRHVSMGLFVPIYFAIVGVKLDLIRNFDPLFFLWFFVLACLVKTFSVWLGARAAGESHPAAMNLAVAMNARGGPGIVLASVAFGAHIINESFFTSLVLLSIISSQIAGAWLGRVVAQGKPLMPPAAGAPAPDSAPDSDSSTSTSTSTSTSEDAASARAGTRNTGR
>NZ_CP016559.1|WP_003955749.1|4673517_4674684_+|Gfo/Idh/MocA-family-oxidoreductase
MDIAIVGTGRDSGVHARWISECPAFSVTAVACDRAAEAEAEAGTDGFGTGTGEAGTVGSGRSGSGTAGSGAVGTGAGAVLDAVRTYHPHAEPAADALALIRHGRIDAVALTGPADGHGLGPARDTLVSEALARGLLVMCEAPLARDRSTALRLAEEAHTRAARAHVALPLRENPALRHARKALAEGAIGDLLTLDVELHDGAAGPDRTAPGRRAAGVLVERGTHALDLVPWLTGTDLWEVASAWTHRVQDTPYPARETDRPDRGGDDIAQAELRTVVRPARARVTVSRTPAPRPQLLVTVRGDRGVLHTRVDTADGSGLLTLATGAREAQQVFGAHPMNPYRRLADDPHARVGLTPGFDDGLAALTLVDAVLTASGTERRQGSVPGNR
>NZ_CP016559.1|WP_003955748.1|4672642_4673527_+|HAD-family-hydrolase
MIVSDLDGTLLDSRGGISERTRAAVRAAHRAGHVFVLASARPVRDVRPIAEALGHRAIAVCSNGAVSYDYARDTVVDHHPMEQADAMGVITALRRRFPGVRLGCERWPDLLLEDGFALDPALSPEARRVRALEEEIDGRGLGKLIVQTEGSAHDYYRVAADALPPGLATVTVSTPAFCEITRRGVTKAMALDLLAGRLSIPVERVVAFGDMPNDLPMLRWAGRSVAMANAHPDVLAAADETTLSNDEDGVAHRLEALLAEASDCAPGSPAPLPPPSPRTTAHRTAQRDKEHPWT
>NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2
MFVILIYDTAVERNPRVLKTCRKYLHWTQRSVFQGELSAAQYRALMAALSGAIDPGYDSIRTYTVRSPEMVETDTLGVDLGGPGDII
>NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MPAVGRTYWLTEPCRIRREDNSVRVERQDGSPVRIPITDIRDLVVFDHVDVNTSALSLLSRSGVTLHVLDHYGNHAGHFSPAESMASAAVVRRQVEITADEEQRLAIGRSLVLASAQNLRWSLDTDLLDPALDSLNAALPGCGSSEAIMGEEGNFRRTAWAVLDQRLPPWLRLNGRTRRPPTNAGNAFISYLNSIVYARVLTALRSTPLHPAIGFLHADTDRRRNTLALDLAEPFKPLFAERLLRRTAHQKHLKQNDFETDVGRASLSKDGRKKIAALVREELATTVYHRSLKRKVSYEELIHLEALKIVRLCLEGQPYKPFRPWW
>NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein
MSPSADPLSDGAAPVGGVHITYLVHCPRQLWLYARGYRPEQRSDLVAFGEVVNETTFPRRRDVDLGEAKIDWVTTGAVVHETKSSRAPAPAHSAQVRHYCLLLERRGVNVRGGVVHYPLVRRTVDVLWDDDARTRAEDAEADAQAVIAAATAPERLTRDQCRGCSYLDYCWGD
>NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3
MTNPPPRASLNDVRAKSTPAEDRERLTTHSRTVHAAVGLIEDRIANAGVLADSPAFWSQVRRAALLHDAGKIAEGFQRQVEPRGIPWGERHEVLSLAYADLLAGAAAWSEDDLTMVATLVATHHRALHNDGGTGHGGKPALSRIYNKETDWEEAFGTSVEDVDGRPVVQVPRFLHRELLAWFCGFLAVDPPSTRPGDPSLAQRARHLLQRLLDTWHHPVRPHRGLLAVLAQGALTLADRSGSAHIGLQTHMPLPYDYLARLPYHPHSHQRQAAETLGHLTLVAPTGSGKTEAGLAWAATQIGTMPGRPRVVWTLPYRASLNAIRRRLSEDLIPVPGERKADIGLLHGTVAQTLLADGLDDDCPGREPNTPPTADQARKARAQAGAMRLFTQRVRVATPHQLLSGAIAGPAYSSVLLEQANCVFVLDELHAYEPRTFGRLCAAMRLWERLGSRFAVLSATLAEVMIRIIEESVEQPVTVHRSPEGSGPVRHRLTLDELPIDAPESVQRIRDWLNEGHSVLAVVNTVARAQELFGQLADDARAARPGDPHAALLLHSRFRNGDRDTIERALLRRHPERRPGDGALRGGLVVATQAVEVSLQLDFDRAAVECAPVEAVAQRAGRVNRRGLHPDGPVEFRVHRVDGPRPYDPDAMDAAWAALRGLVADGATALSEQDIDELLRRAYATEWGKGWEEQARAARDAFAARFLTFTDPFHDRSEFARELSEAFDSTEVLHHDDAEEYRALTRGKAGDPLLASRLLIPLRLGQLRQFDCSFDPYLKVNMTDSAYDPTLGLQPPAARETIL
>NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5
MTGGPRPGARPPTGVPVTEPLSAWRVVFYAPVASFRDPLFPGLTRGLPVPPPSTVRGLLAAATGEPSESLAFGMAAWSEGGGTDDETYHPISASGLNPSVAGRVRPGKGGMTIRSRPFLTGVHLTVWLPGPDGARIADALRRPRWPLRLGRSQDLVHVGERTRVTLNPAEEAAVGSALAPLSGHDVPSATVHRLAASVSTDRMASRWTDYLWCDIPAGRHPVRGAYEDATCRAHPGAEKGQALWLLEP
>NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MAYLAGRMLVSVEAGAPNNGRSADTTARVKYATVRGRRHPYVSAQAVRRWIRDGMVRQGVPASPVTRVGKAQQRAQKANTDADPITYPDDDLFGYMRAGAKKDDDATTLRDSPFMLGTLLSVTPAHPTEDFGVMARGVSEPVLHGHEFYSADLAAPFLLDLPRIGTFTLPNAHGVGRPNYLSQEAALQVARAAALGAGAESFRGQDSVRLPVAERRRRAALLLESIAHLHGGAKQALHYGDRVPHVIVLVPFHGGVNPLTHVITGDEEGLRIRGDVLRGELEAWAGEWEAPVRIGWRPGFRDDLRERFEKECAAEIADRTVVIGHPRTILLELAAEMRDGTTLDHWFEDPVREPVREPVR
>NZ_CP016559.1|WP_003955767.1|4689163_4690612_-|hypothetical-protein
MTAPHPAPTPDPAPLALTGHPLQRAGAWAVTVMAGRKHPEEVSADDLNQVMETVLTDAAGAGAAAKTDSSYDWWKVLFALYPNAKVTHAGRPRDAAALRGALTPMFAPDGTGPGQLPCTFCGTPATAVWAKSMLPLFDSNTALNTLPPGVPGWPVCRGCRIAMWALPYGSWVTAGSATVLSCETTAAEREFALRNVRRAQRIVHAGFEGSAAGVRPELVTLRALRAVGSELSATTLWSFKNDNQEPWLRVTRTRRAVPRFLAAVEGNAALRRGWRLLELALTQRDTDGRVTAQGSVEAARLLFEPEDGRGRYLPSQLHQLLSDTERWPLRDRTALTRLALHYEKEVYGMAPDLEGVATLIVDWIEHGSGSPRGRLAEYKSAGLSDYRLGLLLHQACFRLSFDGRRPVTGPDDWRPFLEKRPRAWEHRMLLTAEVFRLLHQRGIAVGDPPEDPKEREQVERQVNQPLLDTTPEPGYDDYFGGA
>NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6
MRIRVDVATDAPHLTWADVHGPARAVVYRLLEEHDPAIARSLHDDGWRGHPLKPIGVTSPQFKGAPQKNGVYTTSPHGAIWFGSPVPEIAAALVTALARRTEIVWGNARLRVRGFSIEVAAPAPVEGLVELETATPVVVRHERRELLPGDEHYIERLAHNLTHKADVLGLPAPRSLRLLKAGPRRRFSVRGAPRIGAQVRVSMEADPRFVDAIRSWGLGLDTVQGFGWIR
>NZ_CP016559.1|WP_029182926.1|4693111_4694719_+|ATP-binding-protein
MDARPQLINALTALRDRVAAVRLPLPLPGAPRARQTRRELLAQLDDYLIPRLKNPGAPLLAVVGGSTGAGKSTLVNSLVGRRVSEAGVLRPTTRMPVLVCHPDDLHWFEGMRVLPHLTRVWLPRQDDDGDEGGDPGENTPEGGNRLRIETAPSLPRGLALLDAPDIDSLVVENRLLAAELICAADVWVMVTTASRYADAVPWHLLRTAKEYDATLVIVLDRVPHQVVTEVSRQYAALLTKAGLGEVPRFTIPELPESAGGGSGLLPTTAVAPLFGWLAHRVEDPAARQQALGRTATGVIDSLRARMPELAAAVAGQYAAAVRLMGVVEDAYDAEHARLNRQLAAGAVLAGDARTRWRGFPRDSSAGEVLDSLTGSLCSLVQCAVAAADEQVCDSWRWEPGAGALDPAGRLDPEAAERIGITVRRWRRELEELAEDEVSGADLNTAPDPETVAALLAAALLGGRRAKGAGGRLAERIGMPGALRLRERGGELLHICVGTLLGGERDRRLAPLDALDVSPEPQAELIAALSVLQRVK
>NZ_CP016559.1|WP_065757163.1|4694715_4696878_+|ATP-binding-protein
MRTVAAAFDDIAPDTTVSPQRSMRSTRSTGSGSVGESQRGTVGGSQRGTEGDCEGVNPYEKTTDGPGEGKEREPDTGAGRRPRGSRPQAVRWDDGLIARRARPDGRSHPGDRADAPGTPRPGADSGPGGAPENAAGAGPGDGPGSEDLTGYPGGSGAAVRPRGDEPPPFGGTYDGPLRARLDALRELIGLSRTRLESSALAEARRVLDEASARQRLSSRHTVVAIAGATGSGKSTLFNALAQVPLSETGLRRPITSAPIACSWSEGEAGLLDRLAIPPRLRRRPLAGGEEALSGLVLVDLPDHDSALVRHREQVDRVLALVDAVIWVVDPEKYADAALHERYLRPLAGHAEVMFVVLNQVDRLTADAADQVLDDLRGLLDDDGMALGEHGETGATVLALSALTGEGVGELREALGHFVRSRTAAARRLSADVDAAAEELRPAYVAGGRTGLDERARDEFAARLAEAVGAGAAGEAAEREWRRHAVRACRTPWLRLWRWYGRVRTPGSGSPSAVAPVEEEPTARQRVEQAVRAVADEAAAGLPAPWAQAVRETAVRGAEGLPEALDELAAREAAETGKRPLRPAWWPAAVLTQMSMTLLQLYGGLWLTGQIVGVLPPGLTVPALLMAAGVIGGPLVEWACTAAVRGPARRYEQDARRRLREAAAGCGRAMVLDPVAGELMRYREVRERYGTVAGRNATTLVGRSARRRTRSARMGSRARGR

Crispr_ID: NZ_CP016559_15

• CRISPR_ID: NZ_CP016559_15
• CRISPR_location: 4692171-4692593
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: cas6,cas7,cas5,cas3,cas4,cas1,cas2

Consensus repeat of NZ_CP016559_15

Consensus_repeat	Method
GTTGCGAACCCACCAGGGCTGA	CRT
GTTGCGAACCCACCAGGGCTGATGACGAC	CRISPRCasFinder
GTTGCGAACCCACCAGGGCTGATGACGAC	PILER-CR

spacers of NZ_CP016559_15

>15.1|4692193|44|NZ_CP016559|CRT
ATGACGACGGCAAGGCGATCCGTCCCTGCTTCCTTCTCCAGGCC
>15.2|4692259|44|NZ_CP016559|CRT
ATGACGACTGAGATCAGCCATCTGCACGCGGGTCACCAGCCACT
>15.3|4692325|44|NZ_CP016559|CRT
TGGCAACGCCCCGACGCCATGGTCGCCGCCGTCCGCATGGTCAT
>15.4|4692391|43|NZ_CP016559|CRT
TGACGACCCGCACCGGCACGGTCACCGTCCCACGCAATCACAT
>15.5|4692456|43|NZ_CP016559|CRT
TGACGACGGCGGAGACCCGACGCTGGCTCGATGAGGCCGACGC
>15.6|4692521|44|NZ_CP016559|CRT
TGACGACCAGCCGGTCAAGCTCGTCCGCGATCGGGTCGGCCTTG
>15.7|4692332|37|NZ_CP016559|CRISPRCasFinder
GCCCCGACGCCATGGTCGCCGCCGTCCGCATGGTCAT
>15.8|4692398|36|NZ_CP016559|CRISPRCasFinder
CCGCACCGGCACGGTCACCGTCCCACGCAATCACAT
>15.9|4692463|36|NZ_CP016559|CRISPRCasFinder,PILER-CR
GGCGGAGACCCGACGCTGGCTCGATGAGGCCGACGC
>15.10|4692528|37|NZ_CP016559|CRISPRCasFinder,PILER-CR
CAGCCGGTCAAGCTCGTCCGCGATCGGGTCGGCCTTG

CRISPR arrays and Neighbor proteins around NZ_CP016559_15

CRISPR arrays

The CRISPR arrays of NZ_CP016559_15

>merge|NZ_CP016559|15|4692171-4692593|CRT,CRISPRCasFinder,PILER-CR
GTTGCGAATCCCCCAGGGGCTGATGACGACGGCAAGGCGATCCGTCCCTGCTTCCTTCTCCAGGCCGTTACGAACCCACCAGGGACTAATGACGACTGAGATCAGCCATCTGCACGCGGGTCACCAGCCACTGTTGCGAACCCACCAGGGCTGATGGCAACGCCCCGACGCCATGGTCGCCGCCGTCCGCATGGTCATGTTGCGACCCCCCCGGGGCTGATGACGACCCGCACCGGCACGGTCACCGTCCCACGCAATCACATGTTGCGAACCCACCAGGGCTGATGACGACGGCGGAGACCCGACGCTGGCTCGATGAGGCCGACGCGTTGCGAACCCACCAGGGCTGATGACGACCAGCCGGTCAAGCTCGTCCGCGATCGGGTCGGCCTTGGTTGCGAACCCACCAGGGCTGATGACGAC

>NZ_CP016559|15|3|4692171-4692586|CRT
GTTGCGAATCCCCCAGGGGCTG	ATGACGACGGCAAGGCGATCCGTCCCTGCTTCCTTCTCCAGGCC
GTTACGAACCCACCAGGGACTA	ATGACGACTGAGATCAGCCATCTGCACGCGGGTCACCAGCCACT
GTTGCGAACCCACCAGGGCTGA	TGGCAACGCCCCGACGCCATGGTCGCCGCCGTCCGCATGGTCAT
GTTGCGACCCCCCCGGGGCTGA	TGACGACCCGCACCGGCACGGTCACCGTCCCACGCAATCACAT
GTTGCGAACCCACCAGGGCTGA	TGACGACGGCGGAGACCCGACGCTGGCTCGATGAGGCCGACGC
GTTGCGAACCCACCAGGGCTGA	TGACGACCAGCCGGTCAAGCTCGTCCGCGATCGGGTCGGCCTTG
GTTGCGAACCCACCAGGGCTGA

>NZ_CP016559|15|14|4692303-4692593|CRISPRCasFinder
GTTGCGAACCCACCAGGGCTGATGGCAAC	GCCCCGACGCCATGGTCGCCGCCGTCCGCATGGTCAT
GTTGCGACCCCCCCGGGGCTGATGACGAC	CCGCACCGGCACGGTCACCGTCCCACGCAATCACAT
GTTGCGAACCCACCAGGGCTGATGACGAC	GGCGGAGACCCGACGCTGGCTCGATGAGGCCGACGC
GTTGCGAACCCACCAGGGCTGATGACGAC	CAGCCGGTCAAGCTCGTCCGCGATCGGGTCGGCCTTG
GTTGCGAACCCACCAGGGCTGATGACGAC

>NZ_CP016559|15|2|4692434-4692593|PILER-CR
GTTGCGAACCCACCAGGGCTGATGACGAC	GGCGGAGACCCGACGCTGGCTCGATGAGGCCGACGC
GTTGCGAACCCACCAGGGCTGATGACGAC	CAGCCGGTCAAGCTCGTCCGCGATCGGGTCGGCCTTG
GTTGCGAACCCACCAGGGCTGATGACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003960515.1|4698255_4699779_+|TQXA-domain-containing-protein	unknown	unknown	gnl|CDD|274864
NZ_CP016559.1|WP_003960513.1|4700029_4701694_+|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein	unknown	unknown	gnl|CDD|368264
NZ_CP016559.1|WP_065757163.1|4694715_4696878_+|ATP-binding-protein	unknown	unknown	gnl|CDD|206743
NZ_CP016559.1|WP_003960511.1|4703279_4705802_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223481
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NZ_CP016559.1|WP_106428648.1|4705834_4707058_+|N-methyl-L-tryptophan-oxidase	unknown	unknown	gnl|CDD|236887
NZ_CP016559.1|WP_003955767.1|4689163_4690612_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl|CDD|187853
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl|CDD|274215
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl|CDD|187824
NZ_CP016559.1|WP_003955781.1|4701713_4702154_+|acyl-CoA-thioesterase	unknown	unknown	gnl|CDD|223894
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	gnl|CDD|366863
NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028
NZ_CP016559.1|WP_003955783.1|4702150_4702840_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003960509.1|4707069_4708251_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl|CDD|176893
NZ_CP016559.1|WP_029182926.1|4693111_4694719_+|ATP-binding-protein	unknown	unknown	gnl|CDD|366045
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP016559.1|WP_003955777.1|4697101_4697794_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|236092
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	1.8e-19	65.0	1.9
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	3.6e-41	135.7	0.0
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	6.2e-20	67.1	0.0
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	2.6e-87	287.5	0.0
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	4.2e-23	76.1	0.0
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	2.7e-97	320.5	0.0
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	7.5e-53	174.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003960515.1|4698255_4699779_+|TQXA-domain-containing-protein	gnl|CDD|274864	TIGR03934, fibronectin-binding_protein_I_partial, TQXA domain. This model describes a domain of about 40 residues with an invariant TQ dipeptide in an almost invariant TQxA[VI]W motif. This domain occurs in surface-expressed proteins of Gram-positive bacteria, many of which are anchored by LPXTG-containing sortase target domains. Numerous members of this family have domains pfam05738 (Cna protein B-type domain) and pfam08341 (fibronectin-binding protein signal sequence).	8.5378e-11
NZ_CP016559.1|WP_003960513.1|4700029_4701694_+|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein	gnl|CDD|368264	pfam05048, NosD, Periplasmic copper-binding protein (NosD). NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.	2.65019e-14
NZ_CP016559.1|WP_065757163.1|4694715_4696878_+|ATP-binding-protein	gnl|CDD|206743	cd11383, YfjP, YfjP GTPase. The Era (E. coli Ras-like protein)-like YfjP subfamily includes several uncharacterized bacterial GTPases that are similar to Era. They generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain.	7.17954e-37
NZ_CP016559.1|WP_003960511.1|4703279_4705802_+|FAD-dependent-oxidoreductase	gnl|CDD|223481	COG0404, GcvT, Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism].	1.28065e-104
NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	6.94624e-33
NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.75477e-134
NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl|CDD|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	1.26178e-102
NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5	gnl|CDD|187824	cd09693, Cas5_I, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.00967e-17
NZ_CP016559.1|WP_003955781.1|4701713_4702154_+|acyl-CoA-thioesterase	gnl|CDD|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	2.82648e-29
NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein	gnl|CDD|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.11272e-62
NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	9.41376e-84
NZ_CP016559.1|WP_003960509.1|4707069_4708251_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl|CDD|176893	cd08884, RHO_alpha_C_GbcA-like, C-terminal catalytic domain of GbcA (glycine betaine catabolism A) from Pseudomonas aeruginosa PAO1 and related aromatic ring hydroxylating dioxygenases. C-terminal catalytic domain of GbcA (glycine betaine catabolism A) from Pseudomonas aeruginosa PAO1 and related Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs, also known as aromatic ring hydroxylating dioxygenases). RHOs utilize non-heme Fe(II) to catalyze the addition of hydroxyl groups to the aromatic ring, an initial step in the oxidative degradation of aromatic compounds. RHOs are composed of either two or three protein components, and are comprised of an electron transport chain (ETC) and an oxygenase. The ETC transfers reducing equivalents from the electron donor to the oxygenase component, which in turn transfers electrons to the oxygen molecules. The oxygenase components are oligomers, either (alpha)n or (alpha)n(beta)n. The alpha subunits are the catalytic components and have an N-terminal domain, which binds a Rieske-like 2Fe-2S cluster, and a C-terminal domain which binds the non-heme Fe(II). The Fe(II) is co-ordinated by conserved His and Asp residues. GbcA is involved in glycine betaine (GB) catabolism in Pseudomonas aeruginosa; it may remove a methyl group from GB via a dioxygenase mechanism, producing dimethylglycine and formaldehyde. This subfamily belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket.	9.3469e-70
NZ_CP016559.1|WP_106428648.1|4705834_4707058_+|N-methyl-L-tryptophan-oxidase	gnl|CDD|236887	PRK11259, solA, N-methyl-L-tryptophan oxidase.	0
NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.44346e-26
NZ_CP016559.1|WP_003955777.1|4697101_4697794_+|single-stranded-DNA-binding-protein	gnl|CDD|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	2.82096e-18
NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	9.11141e-48
NZ_CP016559.1|WP_029182926.1|4693111_4694719_+|ATP-binding-protein	gnl|CDD|366045	pfam00350, Dynamin_N, Dynamin family.	2.09161e-07

Protein sequences

>NZ_CP016559.1|WP_003955768.1|4690620_4691313_-|CRISPR-associated-endoribonuclease-Cas6
MRIRVDVATDAPHLTWADVHGPARAVVYRLLEEHDPAIARSLHDDGWRGHPLKPIGVTSPQFKGAPQKNGVYTTSPHGAIWFGSPVPEIAAALVTALARRTEIVWGNARLRVRGFSIEVAAPAPVEGLVELETATPVVVRHERRELLPGDEHYIERLAHNLTHKADVLGLPAPRSLRLLKAGPRRRFSVRGAPRIGAQVRVSMEADPRFVDAIRSWGLGLDTVQGFGWIR
>NZ_CP016559.1|WP_003955767.1|4689163_4690612_-|hypothetical-protein
MTAPHPAPTPDPAPLALTGHPLQRAGAWAVTVMAGRKHPEEVSADDLNQVMETVLTDAAGAGAAAKTDSSYDWWKVLFALYPNAKVTHAGRPRDAAALRGALTPMFAPDGTGPGQLPCTFCGTPATAVWAKSMLPLFDSNTALNTLPPGVPGWPVCRGCRIAMWALPYGSWVTAGSATVLSCETTAAEREFALRNVRRAQRIVHAGFEGSAAGVRPELVTLRALRAVGSELSATTLWSFKNDNQEPWLRVTRTRRAVPRFLAAVEGNAALRRGWRLLELALTQRDTDGRVTAQGSVEAARLLFEPEDGRGRYLPSQLHQLLSDTERWPLRDRTALTRLALHYEKEVYGMAPDLEGVATLIVDWIEHGSGSPRGRLAEYKSAGLSDYRLGLLLHQACFRLSFDGRRPVTGPDDWRPFLEKRPRAWEHRMLLTAEVFRLLHQRGIAVGDPPEDPKEREQVERQVNQPLLDTTPEPGYDDYFGGA
>NZ_CP016559.1|WP_003955765.1|4688081_4689164_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MAYLAGRMLVSVEAGAPNNGRSADTTARVKYATVRGRRHPYVSAQAVRRWIRDGMVRQGVPASPVTRVGKAQQRAQKANTDADPITYPDDDLFGYMRAGAKKDDDATTLRDSPFMLGTLLSVTPAHPTEDFGVMARGVSEPVLHGHEFYSADLAAPFLLDLPRIGTFTLPNAHGVGRPNYLSQEAALQVARAAALGAGAESFRGQDSVRLPVAERRRRAALLLESIAHLHGGAKQALHYGDRVPHVIVLVPFHGGVNPLTHVITGDEEGLRIRGDVLRGELEAWAGEWEAPVRIGWRPGFRDDLRERFEKECAAEIADRTVVIGHPRTILLELAAEMRDGTTLDHWFEDPVREPVREPVR
>NZ_CP016559.1|WP_003955764.1|4687338_4688085_-|CRISPR-associated-protein-Cas5
MTGGPRPGARPPTGVPVTEPLSAWRVVFYAPVASFRDPLFPGLTRGLPVPPPSTVRGLLAAATGEPSESLAFGMAAWSEGGGTDDETYHPISASGLNPSVAGRVRPGKGGMTIRSRPFLTGVHLTVWLPGPDGARIADALRRPRWPLRLGRSQDLVHVGERTRVTLNPAEEAAVGSALAPLSGHDVPSATVHRLAASVSTDRMASRWTDYLWCDIPAGRHPVRGAYEDATCRAHPGAEKGQALWLLEP
>NZ_CP016559.1|WP_106428647.1|4684933_4687342_-|CRISPR-associated-helicase/endonuclease-Cas3
MTNPPPRASLNDVRAKSTPAEDRERLTTHSRTVHAAVGLIEDRIANAGVLADSPAFWSQVRRAALLHDAGKIAEGFQRQVEPRGIPWGERHEVLSLAYADLLAGAAAWSEDDLTMVATLVATHHRALHNDGGTGHGGKPALSRIYNKETDWEEAFGTSVEDVDGRPVVQVPRFLHRELLAWFCGFLAVDPPSTRPGDPSLAQRARHLLQRLLDTWHHPVRPHRGLLAVLAQGALTLADRSGSAHIGLQTHMPLPYDYLARLPYHPHSHQRQAAETLGHLTLVAPTGSGKTEAGLAWAATQIGTMPGRPRVVWTLPYRASLNAIRRRLSEDLIPVPGERKADIGLLHGTVAQTLLADGLDDDCPGREPNTPPTADQARKARAQAGAMRLFTQRVRVATPHQLLSGAIAGPAYSSVLLEQANCVFVLDELHAYEPRTFGRLCAAMRLWERLGSRFAVLSATLAEVMIRIIEESVEQPVTVHRSPEGSGPVRHRLTLDELPIDAPESVQRIRDWLNEGHSVLAVVNTVARAQELFGQLADDARAARPGDPHAALLLHSRFRNGDRDTIERALLRRHPERRPGDGALRGGLVVATQAVEVSLQLDFDRAAVECAPVEAVAQRAGRVNRRGLHPDGPVEFRVHRVDGPRPYDPDAMDAAWAALRGLVADGATALSEQDIDELLRRAYATEWGKGWEEQARAARDAFAARFLTFTDPFHDRSEFARELSEAFDSTEVLHHDDAEEYRALTRGKAGDPLLASRLLIPLRLGQLRQFDCSFDPYLKVNMTDSAYDPTLGLQPPAARETIL
>NZ_CP016559.1|WP_003955760.1|4684415_4684937_-|Dna2/Cas4-domain-containing-protein
MSPSADPLSDGAAPVGGVHITYLVHCPRQLWLYARGYRPEQRSDLVAFGEVVNETTFPRRRDVDLGEAKIDWVTTGAVVHETKSSRAPAPAHSAQVRHYCLLLERRGVNVRGGVVHYPLVRRTVDVLWDDDARTRAEDAEADAQAVIAAATAPERLTRDQCRGCSYLDYCWGD
>NZ_CP016559.1|WP_003955759.1|4683435_4684416_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MPAVGRTYWLTEPCRIRREDNSVRVERQDGSPVRIPITDIRDLVVFDHVDVNTSALSLLSRSGVTLHVLDHYGNHAGHFSPAESMASAAVVRRQVEITADEEQRLAIGRSLVLASAQNLRWSLDTDLLDPALDSLNAALPGCGSSEAIMGEEGNFRRTAWAVLDQRLPPWLRLNGRTRRPPTNAGNAFISYLNSIVYARVLTALRSTPLHPAIGFLHADTDRRRNTLALDLAEPFKPLFAERLLRRTAHQKHLKQNDFETDVGRASLSKDGRKKIAALVREELATTVYHRSLKRKVSYEELIHLEALKIVRLCLEGQPYKPFRPWW
>NZ_CP016559.1|WP_003955758.1|4683165_4683429_-|CRISPR-associated-endonuclease-Cas2
MFVILIYDTAVERNPRVLKTCRKYLHWTQRSVFQGELSAAQYRALMAALSGAIDPGYDSIRTYTVRSPEMVETDTLGVDLGGPGDII
>NZ_CP016559.1|WP_003955757.1|4681115_4682393_-|copper-binding-protein
MIRFSRTLSSPWSAAAVGAAVLFGVAAPAPAAHAAPLACGQTVTVSVVLSANLLNCPGDGLIVGGNGITIDLNGRTVDGVGLGVGIRNNGFDNVTVTNSGSTPARVQEFDHGVQLNAGTLGNIVEKLTVQNNEFSGIGLNNAHSDNRVRNNHIDRQAHRGVEITAGSSGNLIADNRITGNQGGGVFAQNAVGNRVERNQISGSGGAGLALEGSRTNTLLANTVGTSSDGAIVLRLGSDGNLVQGNSSSGSADAGLTVSGSAGNRILSNTLHGSGDSGIVLDSAHGSTVTGNDVSRNTGGIELSFANNNTIESNIASNTTGDGISLNGSLNNQLRLNKAENNGSSGIYVVGDAAAGSGNQLVGNIANANKGSGIFVSKAVHTLQGNTARGNNSWGISADRGNVDGGANRAGGNAQSGQCTGVVCAP
>NZ_CP016559.1|WP_003955756.1|4680479_4681049_+|adenine-phosphoribosyltransferase
MDQTGIAPDESLPLSQRLLGRIRDVPDFPQEGIVFKDITPLLADPGAFSDLVDALADLAVRQGATAVAGLEARGFILAAPVALKAGLGFVPVRKAGKLPGPTLAQSYALEYGTAEIEVQRDAFAPGSRVLVVDDVLATGGTLEASIRLIRDAGAQVVAVGLLMELGFLGGRDRLHPTLDGVPMEAVITL
>NZ_CP016559.1|WP_029182926.1|4693111_4694719_+|ATP-binding-protein
MDARPQLINALTALRDRVAAVRLPLPLPGAPRARQTRRELLAQLDDYLIPRLKNPGAPLLAVVGGSTGAGKSTLVNSLVGRRVSEAGVLRPTTRMPVLVCHPDDLHWFEGMRVLPHLTRVWLPRQDDDGDEGGDPGENTPEGGNRLRIETAPSLPRGLALLDAPDIDSLVVENRLLAAELICAADVWVMVTTASRYADAVPWHLLRTAKEYDATLVIVLDRVPHQVVTEVSRQYAALLTKAGLGEVPRFTIPELPESAGGGSGLLPTTAVAPLFGWLAHRVEDPAARQQALGRTATGVIDSLRARMPELAAAVAGQYAAAVRLMGVVEDAYDAEHARLNRQLAAGAVLAGDARTRWRGFPRDSSAGEVLDSLTGSLCSLVQCAVAAADEQVCDSWRWEPGAGALDPAGRLDPEAAERIGITVRRWRRELEELAEDEVSGADLNTAPDPETVAALLAAALLGGRRAKGAGGRLAERIGMPGALRLRERGGELLHICVGTLLGGERDRRLAPLDALDVSPEPQAELIAALSVLQRVK
>NZ_CP016559.1|WP_065757163.1|4694715_4696878_+|ATP-binding-protein
MRTVAAAFDDIAPDTTVSPQRSMRSTRSTGSGSVGESQRGTVGGSQRGTEGDCEGVNPYEKTTDGPGEGKEREPDTGAGRRPRGSRPQAVRWDDGLIARRARPDGRSHPGDRADAPGTPRPGADSGPGGAPENAAGAGPGDGPGSEDLTGYPGGSGAAVRPRGDEPPPFGGTYDGPLRARLDALRELIGLSRTRLESSALAEARRVLDEASARQRLSSRHTVVAIAGATGSGKSTLFNALAQVPLSETGLRRPITSAPIACSWSEGEAGLLDRLAIPPRLRRRPLAGGEEALSGLVLVDLPDHDSALVRHREQVDRVLALVDAVIWVVDPEKYADAALHERYLRPLAGHAEVMFVVLNQVDRLTADAADQVLDDLRGLLDDDGMALGEHGETGATVLALSALTGEGVGELREALGHFVRSRTAAARRLSADVDAAAEELRPAYVAGGRTGLDERARDEFAARLAEAVGAGAAGEAAEREWRRHAVRACRTPWLRLWRWYGRVRTPGSGSPSAVAPVEEEPTARQRVEQAVRAVADEAAAGLPAPWAQAVRETAVRGAEGLPEALDELAAREAAETGKRPLRPAWWPAAVLTQMSMTLLQLYGGLWLTGQIVGVLPPGLTVPALLMAAGVIGGPLVEWACTAAVRGPARRYEQDARRRLREAAAGCGRAMVLDPVAGELMRYREVRERYGTVAGRNATTLVGRSARRRTRSARMGSRARGR
>NZ_CP016559.1|WP_003955777.1|4697101_4697794_+|single-stranded-DNA-binding-protein
MNDPTVTLVGNAATQVEYRETATGGMARFRLAVTPRRWDRVRETWVDGRTSFYTVLAWRGLARNLAGSVAVGEPLLVHGRLRVREGDAEGYRDTRGDDGGGEDRSAVRRWTSVEIDAVAVGHDLSRGTAAFRRAPKAAPPTAAPPLSAAPPPTAVPPADSLGPERDPRGKPAPGPAGDAVEDPLCDEWDEKGRAVPGAAADPVDADSGLPSTVRPGMPPGVPATAVVPPF
>NZ_CP016559.1|WP_003960515.1|4698255_4699779_+|TQXA-domain-containing-protein
MCANFCAPTGDGNGRGRRSLRRSTAAFLTSGLLLAGALTGLGAGTARADDGVRPQDGALATLDGLKTFDRAVVRAKGRSHSIPAGLFEMTVEGGGRLKTYGVDLHDPAQDQARYRETPWRQTALGARREAGRIHWILRNSYPQVDDLTRLAEAAGTGPLTPRTAAAGTQVAIWRYSDGADVVALDPAAEKLADWLERRARPGTEPRASVALEPSAVAGRPGTRIGPVTVRTGAERVSLAPAPAAAADGVEVTDAAGKPVTSVADGARVYIRVPSGARDGSAALTAQTATSVPVGRALTSATGSQAQILAHSSESTVTAQTLAVWAEKGPIPALSARHDCAASQVEITAANADTAPFTFTLADAEHTVPARGSRTVRLPAVEDQPYEVPITGADGFRKSFRGVLDCRTAGAAVPAPSATAPGSGTGSAAEPGTGGPSPMTVPRLAPASADTAPALPDEDLAATGSTGITPLIAGGAAVLMAIGGGVLFTLRRKEPRAAGAERRDPTWE
>NZ_CP016559.1|WP_003960513.1|4700029_4701694_+|energy-dependent-translational-throttle-protein-EttA
MAEYIYTMRKTRKAHGDKVILDDVTLSFLPGAKIGVVGPNGAGKSTVLKIMAGLEQPSNGDAFLSPGYTVGILLQEPPLDESKTVLENVQGGVAEIKGKLDRFNEIAELMATDYSDALLDEMGKLQEELDHANAWDLDAQLEQAMDALGCPPGDWAVTNLSGGEKRRVALCKLLLEAPDLLLLDEPTNHLDAESVQWLEAHLAKYPGTVVAITHDRYFLDNVAGWILELDRGRAIGYEGNYSTYLETKQTRLKVEGQKDAKRAKRLREELEWVRSNAKGRQAKSKARLARYEEMAAEADKMRKLDFEEIQIPPGPRLGSIVVEVENLSKGFGDKLLIDNLSFTLPRNGIVGVIGPNGAGKTTLFKMIQGLEQPDSGSIKVGETVKISYVDQSRANIDPKKSLWAVVSDELDYINVGQVEMPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLLLLDEPTNDLDVETLSSLENALLEFPGAAVVVSHDRWFLDRVATHILAYEGDSKWFWFEGNFESYEKNKVERLGPDAARPHRATYKKLTRG
>NZ_CP016559.1|WP_003955781.1|4701713_4702154_+|acyl-CoA-thioesterase
MTRHIYRCPLRWSDMDAFGHVNNVVFLRYLEEARIDFMFRLRPSDGSPSFSGGSVVARHEIDYVRPLVHRHEPVVIESWVTKIGAAALTIAYEVKDAEGADLVYARASTIVVPYDLEAGRPRRISAEEKSYLQRYLPPVEEDALVG
>NZ_CP016559.1|WP_003955783.1|4702150_4702840_+|hypothetical-protein
MSVPVQRLSCADAREAEDLSAFLARLLRYDRAAAVRLQAGGPDGALPQLAVFGRPPSFEVLAIRAARLAEPARLDVTVSAGELLEAIQGADFTVPGPVTGPPWAGVLPPRGGWRDLAGLPGADRMREAVAAAVAEFRARDEALPEERRTRAERDRVGREIWSRTLGDTPLPLRAVHAAQSLGFLRPGVPAALLASGSWLRLRTPFGSVALRTGGLGPLSVTPTRPPHQH
>NZ_CP016559.1|WP_003960511.1|4703279_4705802_+|FAD-dependent-oxidoreductase
MASRPGGPGASRAPETPAPARRADVPPGAPDPRRVPVVIIGAGIVGCALADELTARGWSAVTVVEQGPLPAPGGSTSHAPGLVFQLNASRTMARLAARTVRAFSGLGAFHPVGGVEIATTEERLADLHRRAGLAASWGLPAEVVPPARCRELWPLLAPGAVLGGLHTPGDGIADALTAATRHRERAAARGARFLDRHTVTAIEQENGHVSAVVTDRGCLPAGRVVAAAGLWGPVIGAMAGVTVPLLPLAHQYARTGQLPRPLPRGLPILRHQEKDLYVRAHDGDTLGIGSYAHRVLPVDPRALPAYDEAPVMPSSLPFTPEDWAPSWDEAVSLLPALGGTAVADAFNGVFSFTPDGMPLLGEAPELGGFWLAEAVWVTHSAGAAEALAQWMTDGHPALDLHECDIARFDEAQRSPAYTAERGARAFAEVYDIVHPLDPPKAPRPLRISPFHQRQRELGAHFLEGGGWERPQWYGANAALLDDPDLFPGGERPPARDTWAARHWSPVVAAEARATRERVALHDMTPLRRLEVTGPGALAFLQRMTTNQLARPVGSVSYTLLLDERAGIRSDLTVTRLGEDRFQLGANTPADLDWLLRHAPAAVQIRDITSGTCCIGVWGPRARALIQPLTRDDFSHRGFGYFRARRTHLGDVPVLALRLSYVGELGWELYTTPDLGLRLWDTLWEAGAALGLTAAGRGALESLRLEKGYRAWGRDMTTEDTPYEAGLGFVVRPEKGDFTGRNALGPRNPARRLTCLTLDDPAAVVLGKEPVHLLGAPAPAGHVTSAAYGYTIGRCVAYAWLPALPVGTPVHIAYFGEKIPATVAEEPLVDPEMTRIRSAAG
>NZ_CP016559.1|WP_106428648.1|4705834_4707058_+|N-methyl-L-tryptophan-oxidase
MPRTARTPGAARTAGAARTARRKAAHDVIVLGLGGMGSAAAAHLAARGARVLGLEKHGPVHRHGSSHGGSRVTRQSYFEDPAYVPLLLRAYELYEQVERDTGREIALLCGGVMVGTPASRTVAGARRSAEAWGLPHELLDARELRRRFPTFTPAENEIGLYEARAGLLRPESTVAAHLQLALRHGAELHFQEPAVRWEPYRDGVRVHTPEDTYTAGHLVICPGAWAPRLLADLGVPIRIERQIMYWFQPRGGTGPYAPDRHPIYVWEDAAGVQVYGFPAIDGPDGGAKAAFFRRNGTPCTPETIDRTVHEHEVRAMARQLDGCLPTLPGTLLKAVTCMYSTTPDEHFVIARHPEHPGHTTVACGFSGHGFKFVTVVGEILADLALDGTTRHPIALFDPGRFAAPAPA
>NZ_CP016559.1|WP_003960509.1|4707069_4708251_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MAEPSRPGTTSASGITGASPGAPAPTPGGSLIATLPGAAYSSPEIFAREQEAVFENLWCCVLRSAELAAPGDFRTVTVGRESVLVLRNTAGELRAFLNVCSHRGTRLCAGESGTVRRTLRCSYHAWSYDLDGTLVAAPNLARMPDLDRTAYGLRPVALREWLGYTWLCLAEEPPSFDEHVRGAATERLGDPAAIDRYDAEGLMLGHRVRYDVRANWKLLVENFMECYHCSTIHPELVAVLPEFGGGYAAQTKVGQGASFAGAARGFTVDGGPGFERLPGLAEEQDRRYFAITVRPQVFINLVPDHVILHRMFPHAHDRTVVECDWLYAPDVVASGADLSHSVELFHRVNEQDFAVCERTQPGMASRAYRAGGVLVPAEHHIGEFHAWVTRMLA

Crispr_ID: NZ_CP016559_16

• CRISPR_ID: NZ_CP016559_16
• CRISPR_location: 4922963-4923067
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_16

Consensus_repeat	Method
ATCCCCTGTAGCTCAATTGGCAGAGCA	CRISPRCasFinder

spacers of NZ_CP016559_16

>16.1|4922990|51|NZ_CP016559|CRISPRCasFinder
GCCGGCTGTTAACCGGCAGGTTACTGGTTCGAGTCCAGTCGGGGGAGCGCG

CRISPR arrays and Neighbor proteins around NZ_CP016559_16

CRISPR arrays

The CRISPR arrays of NZ_CP016559_16

>merge|NZ_CP016559|16|4922963-4923067|CRISPRCasFinder
ATCCCCTGTAGCTCAATTGGCAGAGCAGCCGGCTGTTAACCGGCAGGTTACTGGTTCGAGTCCAGTCGGGGGAGCGCGATCCCCTGTAGCTCAATTGGCAGAGCA

>NZ_CP016559|16|15|4922963-4923067|CRISPRCasFinder
ATCCCCTGTAGCTCAATTGGCAGAGCA	GCCGGCTGTTAACCGGCAGGTTACTGGTTCGAGTCCAGTCGGGGGAGCGCG
ATCCCCTGTAGCTCAATTGGCAGAGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003960394.1|4913461_4915375_+|DNA-primase	unknown	unknown	gnl|CDD|235551
NZ_CP016559.1|WP_003954039.1|4931278_4931995_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003954029.1|4921009_4922446_-|sugar-kinase	unknown	unknown	gnl|CDD|198375
NZ_CP016559.1|WP_009996129.1|4922482_4922782_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003954033.1|4924351_4925938_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003960395.1|4912101_4913370_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|170080
NZ_CP016559.1|WP_003960386.1|4929258_4930311_-|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP016559.1|WP_003954020.1|4909745_4910450_-|DUF218-domain-containing-protein	unknown	unknown	gnl|CDD|225500
NZ_CP016559.1|WP_003960396.1|4910542_4911922_+|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098
NZ_CP016559.1|WP_003960389.1|4927648_4928323_-|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NZ_CP016559.1|WP_003960390.1|4923545_4924355_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003960397.1|4908342_4908945_-|TIGR03086-family-protein	unknown	unknown	gnl|CDD|274424
NZ_CP016559.1|WP_003954034.1|4925934_4926825_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213231
NZ_CP016559.1|WP_003960385.1|4930307_4931249_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003954040.1|4932006_4932216_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_009996130.1|4918777_4920511_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP016559.1|WP_129555063.1|4928390_4928768_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003954035.1|4926821_4927652_-|membrane-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003954025.1|4915655_4916813_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|235640
NZ_CP016559.1|WP_003954026.1|4916846_4918781_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003960394.1|4913461_4915375_+|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP016559.1|WP_003954029.1|4921009_4922446_-|sugar-kinase	gnl|CDD|198375	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases. This subgroup is composed of D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17) from bacteria and eukaryota. They share high sequence similarity with Escherichia coli xylulokinase (EcXK), which catalyzes the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. Some uncharacterized sequences are also included in this subfamily. EcXK exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ might be required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	8.99104e-114
NZ_CP016559.1|WP_003954026.1|4916846_4918781_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP016559.1|WP_003960395.1|4912101_4913370_+|FAD-dependent-oxidoreductase	gnl|CDD|170080	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional.	3.19356e-75
NZ_CP016559.1|WP_003960386.1|4929258_4930311_-|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	5.82479e-44
NZ_CP016559.1|WP_003954020.1|4909745_4910450_-|DUF218-domain-containing-protein	gnl|CDD|225500	COG2949, SanA, Uncharacterized membrane protein [Function unknown].	4.72198e-55
NZ_CP016559.1|WP_003960396.1|4910542_4911922_+|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NZ_CP016559.1|WP_003960389.1|4927648_4928323_-|RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	6.05668e-29
NZ_CP016559.1|WP_003960397.1|4908342_4908945_-|TIGR03086-family-protein	gnl|CDD|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	8.03913e-54
NZ_CP016559.1|WP_003954034.1|4925934_4926825_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.17269e-100
NZ_CP016559.1|WP_009996130.1|4918777_4920511_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.39995e-157
NZ_CP016559.1|WP_003954025.1|4915655_4916813_+|RNA-polymerase-sigma-factor	gnl|CDD|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	1.10762e-161

Protein sequences

>NZ_CP016559.1|WP_009996129.1|4922482_4922782_-|hypothetical-protein
MRYRLTFVAGLALGYVLGTRAGRERYEQLRKSVRQISQNPAVRNAAESAALEGRQLAGRAFHAVSDKIGDRVPESVAERVRSLRERGTNGEDDWGTSNT
>NZ_CP016559.1|WP_003954029.1|4921009_4922446_-|sugar-kinase
MGIVAGLDSSSAFTQIVVCDADTGAVLRQGYAPHAVDPKAVEADPQTWLLSLGEAATGGLLEGVQAIGVCAQQGLVPLDQQGTLVRPALLGNDKRAQVAAADLIDGLGGREYWAHAVGSVPQATHPVAKLRWLARTEPQAARRVAAVLQPHDWLVWQLLGRPPRRTTDRGSASGTGYWSAGTGGYRPDLVELALGHQCALPEVLGPADAAGTTPEGLLISAGTGETMAAALGLGVRPGDAVISLGATGSVMAVHHEALADPHGMITSYADATGLHLPVVHTLNAVRVLRGTAEMLGVDDLDTLSGLALKSTPGSCGLVLLPYLEGERTPRLPHTAGTLSGLRRESMKPEHLARAAFEGMLCSLADALDVLRGRGVDVRRVFLLGASAGLPAVQAVAPGIFGTQVVVPQPADYTALGAARQAAWALGVAHGTLSPAAPPHWPEPALQILDPGDTAAVGHAIRQQYAATRDQLHPGAFGY
>NZ_CP016559.1|WP_009996130.1|4918777_4920511_-|ABC-transporter-ATP-binding-protein
MLIQLLRSHLAPYRQPITLLVVLQLLQTSATLYLPNLNADIIDKGVVRGDTGEIMRLGAVMIGISLVQVVCNIGAVYYGARTAAALGRDVRTAVFDRVQSFSAREVGHFGAPSLITRTTNDVLQVQTLVLMSFTLMVSAPIMCVGGIVMALGQDVALSTVLLAVVPVLGIAVTLLVLRMRPLFRAMQERLDTVNRVLREQITGNRVIRAFVRDGYEQERFRAANTDLTEVALGTGRLTALMFPTVLTVVNVSSVAVVWFGAHRIDSGAIEIGQLTAFLAYLMQIVMAVMMATFMFMMVPRAEVCAERIQEVLDTPSSVAPPAEPVRELSRHGHLEIRDVDFSYPGAEESVLRSIGLVARPGETTAVIGSTGSGKSTLLGLVPRLFDVTDGAVLVDGADVRDLDPDLLARTVGLVPQKPYLFSGTVATNLRYGRPDADDEELWHALEVAQAADFVRELDAGLNAPIAQGGTNVSGGQRQRLAIARTLVQRPEIYLFDDSFSALDYATDAALRSALAAETAEATVVIVAQRVSTIREADRIVVLDEGRVVGTGTHRELMAGNETYREIVLSQLTEAEAA
>NZ_CP016559.1|WP_003954026.1|4916846_4918781_-|ABC-transporter-ATP-binding-protein
MSSPRVMMGGSAERSMDFKGSGKRLLKQLAPDRALLWVMLAAAVLSVGLSVAGPMVLGWATDRVFAGVVGRELPEGTTKEETVERLRSEGDGSLADMLSGVDFVPGRGIDFGAVGEVLLIALALFVVSGLLALVSTRLAIVVINRSMHRMRAEVQAKLSRLPLSYFDRAKRGEVLSRVTNDIDNISQTLQQTMGQLINSLLTIVGVLGMMFWVSPLLALVALVTVPVSVVVAARVGKRSQPHFVQQWKSTGKLNAHIEEMYTGHTLVKVFGRQRESAGQFAEQNEALYEAGFKAQFHSGVMQPLMFFVSNLNYVLVAVVGGLRVASGSLSIGEVQAFIQYSRQFSMPLTQVASMANLVQSGVASAERVFELLDAEEQEADGPSVERPERPAGQVSLEKVSFRYEPDRPLIEDLSLRVEPGQTVAIVGPTGAGKTTLVNLLMRFYEVTGGRIGLDGVDVAKMSRDELRSSIGMVLQDTWLFGGTIADNIAYGAAPGRKVTRAEIEEAARAAHAHRFIRTLPDGYDTVLADDGAEGAGVSAGEKQLITIARAFLSDPVILVLDEATSSVDTRTEVLIQKAMARLAHGRTSFVIAHRLSTIRDADVILVMENGSIVEQGTHDELLTAGGAYARLYSAQFAEAVAEVD
>NZ_CP016559.1|WP_003954025.1|4915655_4916813_+|RNA-polymerase-sigma-factor
MQTRTLTETPAERSARPDPLPAVPAQSPSPHHPEAPAAEALQDGAGAEENAEESAEAIGGTGAEESAPRPGSARTARSESSGPSSDLFRQYLREIGRIPLLTAAEEVELARRVEAGLFAEEKLAATPDLNSSRLAADLDRLVVMGRMAKRRLIEANLRLVVSVAKRYVGRGLTMLDLVQEGNLGLIRAVEKFDYTRGYKFSTYATWWIRQAMSRALADQARTIRVPVHVVELINRVVRVQRRMLQEQGSEPTPEEVAAQLDLPPERVSEVLRLAQEPVSLHAPVGEEEDVALGDLIEDGDAASPVESAAFLLLREHLEAVLSTLGERERKVVQLRYGLADGRPRTLEEIGRIFGVTRERIRQIESKTLNKLRDHAFADQLRGYLD
>NZ_CP016559.1|WP_003960394.1|4913461_4915375_+|DNA-primase
MAGRINDDDIKAVRDAVPIDAVVSEYLQLRNAGGGNLKGLCPFHDEKSPSFQVSPGKGLFHCFGCQEGGDTIAFVMKIDHLTFSEAVERLAGTAGITLRYEEGGYNPSHQRGERIRLVEAHKVAAQYYAEQLENSPEAAAGRTFLAERGFDQAAALHFGVGYSPQGWDHLTRFLRGKGFSDKELTLSGLSQEGRRGPIDRFRGRLMWPIRDISGDVVGFGARKLHESDNGPKYLNTPETAIYKKSQVLYGIDLAKKEIVRTSTAVVVEGYTDVMACHLAGVTTAIATCGTAFGGDHIKILRRLLMDHATAEVIFTFDGDAAGQKAALRAFEDDQKFAAETSIAITPGGMDPCDLRLAEGDAAVEALVGSRTPLFEFAMRQIVQRHNLENPAGQAGALDEAAPVVAKIKNPAIQHGSAVQLAGMIGILDTQFVVKRVAQLARWARDRGGRGPAPGDTRRRGPQPPQQATAPAPAGGPALHLRSPAHRTERELLKLALQHPELVSPAFDAYGMDEFTAAPYAAVRQTVADAGGTEQGLSDGPGYLARVREAAPNDTVRALVTELAVEAIHARTVDEIYAGVQLVQVRLRAVDRRVLEIQGTLTRLGQHADPERFSAVQNELWVLQQYAQSLRTHGAAAL
>NZ_CP016559.1|WP_003960395.1|4912101_4913370_+|FAD-dependent-oxidoreductase
MVDGHQTFVIVGGGLAGAKAAETLRQEGFTGRVILVGDERDHPYERPPLSKGYLLGKDERDSVFVHEPSWYAQADVELHLGQSVVAVDRAARTVRLSDGTVLGYDKLLLATGAEPRRLDIPGTSLAGVHHLRRLAHAERLRQVLASLGRDNGQLVIAGAGWIGLEVAAAARSYGAEVTVIEPEPTPLHQAIGPELGQFFADLHTEHGVRFHFGARLTEITGQDGMVLGVRTDDGDEHPAHDVLAAIGAAPRTALAEAAGLTLADRAHGGGIAVDASLRTSDPDIYAAGDVAAAEHPGIGARLRVEHWANALNGGPAAARAMLGQEVAYDRVPYFFSDQYDLGMEYSGWAPAGSYDQVVVRGDAGKREFIAFWLKEGRVLAGMNVNVWDVTAPIQQLIRSGGAVDADALADPSVPLDSLSGQG
>NZ_CP016559.1|WP_003960396.1|4910542_4911922_+|deoxyguanosinetriphosphate-triphosphohydrolase
MAGTTGTTHHPDQPRRTDTRHGTPGPGTGAEGGHGASGPYDGAATARFAPEPDKRPGRTAFQRDRARVLHSSALRRLAGKTQVVTPGTRHPAWDASPRTRLTHSLECAQVGRELGAALGCDPDLVEAACLSHDMGHPPFGHNGESVLNEIAKDIGGFEGNAQSLRLLTRIEPKRFVHTPGGDVVSVGLNLTRAALDAATKYPWPRGGRPTDPGSAKFGVYEDDLPVFAWVREGAPEGRTCFEAQVMDWSDDVAYSVHDLEDALHAGHVDPRALLSAAERKAVLEVAISRYTPADTDPEELSAALERLLAQEWWPHEYDGSALAQARLKDATSQLIGRFCLAAEEATRLAHGTGRLTRYGAELVVPAETRLECAVLKAVADRYVMRRADQEAIRAEQRVLLTELADALAARAPEGLEPQFHALFTAADDDRERGRVIVDQLASLTDAAARALHARLTARP
>NZ_CP016559.1|WP_003954020.1|4909745_4910450_-|DUF218-domain-containing-protein
MTQTGTPSRPLPRLRLPRTRRGKRWLVRGAMFVCVLALLPATWTHRVADRHVHAAEDVPAQDVALVFGAGLWQGRPTPYLAHRLDTAADLYRRGKVKVILVTGDNSREEYDEPDAMRTYLVGRGVPERRIVSDHAGFDSWDSCVRAKEIFGVDRAVLVSQGFHIRRAVALCRTAGIESYGVGVAEPFDSHRIHGAVRELGAAGKAALDAALRPDPRFLGERERGVREALADARG
>NZ_CP016559.1|WP_003960397.1|4908342_4908945_-|TIGR03086-family-protein
MGINDTGGTRDATALLARHAEALALFGDRVHAVRADQWDEATPCTEWSVRDLVNHLTAEQLWVPDLVTEGSTVTEVGGVHDGDVLGTRPKTSWDSAARAARKAFAAPGALERTVWLSYGQTPAVAYCAQMITDAVVHAWDLSRAIGADERLPEALVAFALEEVTPYAAGLSDSGLFAPPIEPPPGDGHQTRLLALLGRRA
>NZ_CP016559.1|WP_003960390.1|4923545_4924355_-|hypothetical-protein
MIAPRTAPAAGPVPRKRKKAVSGRRYAAQVRALLPFERRAARTGPLLWGAAVGIVSCAVPAVFGLSLVPGAAAALLFLSAVVGAVGTVFALEDRAAPTTGLCPSPWWLRRSLRTASALLLLTVAWCAGAALVHQALPPAERPVFPYADAAVAALALSLLAMALALLTARFTQGRGNGAAAASAFALCVLVLLFLPSGIELFSSPEDLPRWEAAAARWDVFALLLAPVTALLHRQPPPREGGNGKRRGVSPALGRGPGARDLRRSQHDHQ
>NZ_CP016559.1|WP_003954033.1|4924351_4925938_-|hypothetical-protein
MSAIRQEAPPASAHRATGSRPVRSLAVVEASRLIRHPLVLGTMALCCVLWIYQTAVTHDTAFPVLHDQDRYLQTQLLILAAGVFLGTHIAVLRSARDETEPWFALMVLTPWQRTAAHLLAVLPVAGLAALLVTVRIVWLALLPGAIGSPSPAELATSPAVVLLAGTLAVLTGTLVRAVAAGPLILGVAAIATVAGGIADSSSWRWLLPTAEEDDMRTALPAHLLDRPAGPHLVYVLLLVAVCAVGALLRAGMASAAVRTAGVLALVGAVSVGALQLQHARDGAAEAQALDSPSRQQRCAEEGGVRYCAYPDFTDRREQWAPVARAILAPLPVEARNARYVVRQHISPDTGPLVVLDVAGMLRKWALDDRRAGTPGAVVVGTHWGDHSDQGSDATAGFATEFAHRAVAGEGAALDAASPSGTVRACGARAVVSVWLAGQAAPMTERALRSVLGRSGGDVVGFAGTLSTTEFGRMETDLGMALLDRPRDDVARGVRRSWDELTAAATTARRAAELLGVPVPAGSGKGCAS
>NZ_CP016559.1|WP_003954034.1|4925934_4926825_-|ABC-transporter-ATP-binding-protein
MTIRPGAGDGTSVDRLTVRYRKAHALDGISLSLGSGVTGLLGPNGAGKTTLMRVLATASIPSEGEVTVLGRDPRVPAQRQDIRRRLGYLPQTPGFHHHFTAFEFVDYVAILKEHTDRRGRHDEVRRVLEAVGLSQDRSKKIKALSGGMRQRVALAAALIGDPELLILDEPTVGLDPEQRLRFRELIADIAARRPVLLSTHQTEDVAALCHRVIVMGRGRVRHDSSPRELSEVARGAVWFSGERDPRALAGWRTGTGAFRNIGSPPPGAELAEPTLEDAYLLLNADLPAHTQEGSTP
>NZ_CP016559.1|WP_003954035.1|4926821_4927652_-|membrane-protein
MTRDSTGGRHPLPDALRRYALGTLGAVEIRSVEPHIDACADCRAQIAVVSDPVPIERGWQRLDHALDTPVPGRCERLLLTVGVSDHTARLLAATAMLRSSWLCGTALTLVLTVLLARSAAAAAPVSFLAVAPLLPAAGIAVSIGRHSDPAYELGKVAAPSGFRLVLLRMTAVLAATLPLTALAALSLPVSGFRAFCWVLPSLLVTVLCLLLLPRTGAMPAATVSVGVWLTAVFLTRHSDLLFSPAAQAVLAGMLLAALLLLLLLRADFDFDKEIRV
>NZ_CP016559.1|WP_003960389.1|4927648_4928323_-|RNA-polymerase-sigma-factor
MDEKPDDELLAAMAESDRDAFEALYRRYAPWLRARLGYRCADITQLDDAVQEAFLSVWRICARGHPPEVRDCAGWLWRIAERRLIDAARTHRSQGRLHQLLAGLRRPGVPSAEEQALEAGEFSGAHTALRRLPEELRAVVQATVIDGLTTRQAADRLGLPVGTVKTRAMRARGRLREELAHGEGTGQVPESGIAPGGRRRESGDRLRRGFRPGPAKRTSGERET
>NZ_CP016559.1|WP_129555063.1|4928390_4928768_-|hypothetical-protein
MSAPAPTEFADATAMELAERSTTIPPAMTVLANLRITLSFLFGLTKDQTMNEKEVMQGQGNATRGPSRNTEGNGYTRNPRRSGVNRETPSPHVRRDMNTPRTDNTEEQPKVIKRNRQAATEGELM
>NZ_CP016559.1|WP_003960386.1|4929258_4930311_-|serine-hydrolase
MMRADTAGFLLTGHVRRLVDEGAATAAAGAVIRGPDRAAAVFGHRARPTADDVPPAGPDTLFALGSVTKTFTALLLAEMAAAGVVSYDDPIENHLPPEAGPRAGADPITLGELASHGGGLPRLPGNLYRRAWKRWLSDPYACYGTADLYRATARLRPRPAPRPVRYSTFGAGLLGQLLANAARTPYPELLTRRVLAPLGLRRTTVPDEETLTAHAATGHRGRRPVGHWRFDALAGAGALYSSPTDLLRYLHALLEPATAPPPLTAALTAVREPRRPTGPGPTHKTLGWDLREVHGRTLLWHTGGTGGFTCYTAFCPDAGTAVAVLANTTPTRRETTLRAGRRLFREVTFD
>NZ_CP016559.1|WP_003960385.1|4930307_4931249_-|hypothetical-protein
MDAEAVRLARQVSEGAVEWLGRMRGAFALCRDVPDYEIDANQLKALSELALAAGTVHREAVAGHRCAATAESLLEYAWRQFDEGELLYRLQVYTPAATHPMEIYGLFAAVDLRHQRMDDLSAHLMGLRAARSTEHLPNRRLAVAASARRIGVPIQDDIKALTDQTWLGGTPEPWMMDTNNAYGVTHTVFHLTDYGNDPDGLAEPLQDYLHLWLPVWVEVFAETRFWDLLLEFLIVGTCLKRPLFFPEVWRQVALAQQNDGMMPNGLTVPPAEAHLAWVNHHHPTIVAAVAGTLTVSRALTLTTAAATAGAGSA
>NZ_CP016559.1|WP_003954039.1|4931278_4931995_-|hypothetical-protein
MTTPHQPSPGSVETATCVLAGALTRALQEDGDAFGVSRSLGAWGDRTGGLAAVRVLGADVLTPFVLTGRPLPAEDAALVRTAVRAHPAPRHQPLEAALWGARDAALVRALAALGVDGADWEGLAPASPSPDGLAADWMSLTAVLVPLASAAHPFTDTALRTQLAGRRLDLSRGLVRALLRRDLLSAARMARWLVLDASATVPDLVGPALEHLATLGADDPRVQLEVAVARRLTARARC
>NZ_CP016559.1|WP_003954040.1|4932006_4932216_-|hypothetical-protein
MTVESAVTNEVRALIAAEGEASRSFGPGSIKGVGAIALLLLLSANPRRNEPIEDAFGGSVQNLACAAAF

Crispr_ID: NZ_CP016559_17

• CRISPR_ID: NZ_CP016559_17
• CRISPR_location: 5674791-5674879
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_17

Consensus_repeat	Method
GTGCCTCCCGCTCGCGGGAGTGCCG	CRISPRCasFinder

spacers of NZ_CP016559_17

>17.1|5674816|39|NZ_CP016559|CRISPRCasFinder
TACGCAGGACGAAGACGGCGCCGCGGAAGCGGGCCACGT

CRISPR arrays and Neighbor proteins around NZ_CP016559_17

CRISPR arrays

The CRISPR arrays of NZ_CP016559_17

>merge|NZ_CP016559|17|5674791-5674879|CRISPRCasFinder
GTGCCTCCCGCTCGCGGGAGTGCCGTACGCAGGACGAAGACGGCGCCGCGGAAGCGGGCCACGTGTGCCTCCCGCTCGCGGGGGTGCCG

>NZ_CP016559|17|16|5674791-5674879|CRISPRCasFinder
GTGCCTCCCGCTCGCGGGAGTGCCG	TACGCAGGACGAAGACGGCGCCGCGGAAGCGGGCCACGT
GTGCCTCCCGCTCGCGGGGGTGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003959944.1|5666641_5667196_+|hypothetical-protein	unknown	unknown	gnl|CDD|237865
NZ_CP016559.1|WP_009995663.1|5686687_5687728_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486
NZ_CP016559.1|WP_003958408.1|5673672_5674758_+|prephenate-dehydrogenase	unknown	unknown	gnl|CDD|235824
NZ_CP016559.1|WP_003959941.1|5671349_5672384_+|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl|CDD|377122
NZ_CP016559.1|WP_003958407.1|5675549_5676236_+|(d)CMP-kinase	unknown	unknown	gnl|CDD|234579
NZ_CP016559.1|WP_003958401.1|5684291_5686001_-|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl|CDD|238832
NZ_CP016559.1|WP_009995667.1|5678529_5678910_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003959940.1|5672428_5673121_-|nucleotidyltransferase	unknown	unknown	gnl|CDD|313370
NZ_CP016559.1|WP_003959942.1|5668506_5669163_+|SMC-Scp-complex-subunit-ScpB	unknown	unknown	gnl|CDD|377219
NZ_CP016559.1|WP_003959943.1|5667298_5668510_+|segregation/condensation-protein-A	unknown	unknown	gnl|CDD|280735
NZ_CP016559.1|WP_003958412.1|5670537_5671353_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|223979
NZ_CP016559.1|WP_065757186.1|5679104_5679950_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003959939.1|5676232_5676934_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_CP016559.1|WP_009995668.1|5676993_5678442_+|ribosome-biogenesis-GTPase-Der	unknown	unknown	gnl|CDD|179525
NZ_CP016559.1|WP_003958403.1|5681373_5682645_+|glycosyltransferase	unknown	unknown	gnl|CDD|340847
NZ_CP016559.1|WP_003959936.1|5680484_5681213_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|369056
NZ_CP016559.1|WP_044972352.1|5665619_5666645_+|ParA-family-protein	unknown	unknown	gnl|CDD|379293
NZ_CP016559.1|WP_003959933.1|5686299_5686515_+|hypothetical-protein	unknown	unknown	gnl|CDD|288556
NZ_CP016559.1|WP_003958413.1|5669201_5670332_+|rRNA-pseudouridine-synthase	unknown	unknown	gnl|CDD|224108
NZ_CP016559.1|WP_003958409.1|5673313_5673676_+|chorismate-mutase	unknown	unknown	gnl|CDD|377905

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003959944.1|5666641_5667196_+|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	0.000295877
NZ_CP016559.1|WP_009995663.1|5686687_5687728_-|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	7.73835e-29
NZ_CP016559.1|WP_003958408.1|5673672_5674758_+|prephenate-dehydrogenase	gnl|CDD|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	1.75409e-125
NZ_CP016559.1|WP_003959941.1|5671349_5672384_+|ADP-ribosylglycohydrolase-family-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	7.40895e-35
NZ_CP016559.1|WP_003958407.1|5675549_5676236_+|(d)CMP-kinase	gnl|CDD|234579	PRK00023, cmk, (d)CMP kinase.	1.01971e-96
NZ_CP016559.1|WP_003958401.1|5684291_5686001_-|cytochrome-c-oxidase-subunit-I	gnl|CDD|238832	cd01662, Ubiquinol_Oxidase_I, Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits in ubiquinol oxidase varies from two to five. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons from ubiquinol to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from ubiquinol on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. It is generally believed that the channels contain water molecules that act as 'proton wires' to transfer the protons. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are believed to be transferred directly from ubiquinol (the electron donor) to the low-spin heme, and directly from the low-spin heme to the binuclear center.	0
NZ_CP016559.1|WP_003959940.1|5672428_5673121_-|nucleotidyltransferase	gnl|CDD|313370	pfam10127, Nuc-transf, Predicted nucleotidyltransferase. Members of this family of bacterial proteins catalyze the transfer of nucleotide residues from nucleoside diphosphates or triphosphates into dimer or polymer forms.	1.39139e-41
NZ_CP016559.1|WP_003959942.1|5668506_5669163_+|SMC-Scp-complex-subunit-ScpB	gnl|CDD|377219	pfam04079, SMC_ScpB, Segregation and condensation complex subunit ScpB. This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.	9.4673e-67
NZ_CP016559.1|WP_003959943.1|5667298_5668510_+|segregation/condensation-protein-A	gnl|CDD|280735	pfam02616, SMC_ScpA, Segregation and condensation protein ScpA. This is a family of proteins that from part of the condensin complex that regulates chromosome segregation. This is the A subunit, which binds to the ScpB subunit, pfam04079, and SMC, pfam02463, to participate in chromosomal partition during cell division. The condensin complex pulls DNA away from the mid-cell into both cell halves. These proteins are part of the Kleisin superfamily.	2.33171e-52
NZ_CP016559.1|WP_003958412.1|5670537_5671353_+|NUDIX-hydrolase	gnl|CDD|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	1.96215e-28
NZ_CP016559.1|WP_003959939.1|5676232_5676934_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.44675e-32
NZ_CP016559.1|WP_009995668.1|5676993_5678442_+|ribosome-biogenesis-GTPase-Der	gnl|CDD|179525	PRK03003, PRK03003, GTP-binding protein Der; Reviewed.	0
NZ_CP016559.1|WP_003958403.1|5681373_5682645_+|glycosyltransferase	gnl|CDD|340847	cd03820, GT4_AmsD-like, amylovoran biosynthesis glycosyltransferase AmsD and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.	5.32931e-99
NZ_CP016559.1|WP_003959936.1|5680484_5681213_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|369056	pfam06737, Transglycosylas, Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.	4.30621e-34
NZ_CP016559.1|WP_044972352.1|5665619_5666645_+|ParA-family-protein	gnl|CDD|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	1.29496e-87
NZ_CP016559.1|WP_003959933.1|5686299_5686515_+|hypothetical-protein	gnl|CDD|288556	pfam11720, Inhibitor_I78, Peptidase inhibitor I78 family. This family includes Aspergillus elastase inhibitor and belongs to MEROPS peptidase inhibitor family I78.	0.00244243
NZ_CP016559.1|WP_003958413.1|5669201_5670332_+|rRNA-pseudouridine-synthase	gnl|CDD|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	1.3737e-84
NZ_CP016559.1|WP_003958409.1|5673313_5673676_+|chorismate-mutase	gnl|CDD|377905	pfam07736, CM_1, Chorismate mutase type I. Chorismate mutase EC:5.4.99.5 catalyzes the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine.	1.02699e-53

Protein sequences

>NZ_CP016559.1|WP_003958408.1|5673672_5674758_+|prephenate-dehydrogenase
MRTAAVIGTGLIGTSAALALSGRGVTVHLIDHDPERARTAAALGAGTDDPLEGPVDLAVVAVPPALTATALADAMRAGIARGYLDVASVKGGPRRELEALSLDLSSYIGTHPMSGKERSGPLAATADLFEGRPWVLTPTPVTDTEVLNLALELVALCRAVPVVMDADAHDRAVALVSHTPQLVSSMVAARLREADETAVRLCGQGIRDVTRIAASDPRMWVDILSANPGPVADVLSGIAADLDGTVAALRALASADPAKREDGVGAIEDVLRRGNAGRSRVPGKHGAAPAAYEIVAVLISDEPGELARIFADAGRAAVNIEDVRIEHATGQQAGLVQLMVEPAAAAVLSATLRERGWSIRH
>NZ_CP016559.1|WP_003958409.1|5673313_5673676_+|chorismate-mutase
MAVRAVRGAVQLERDEAGHMDERVSALLTAILERNGIDEDDLISVWFTATPDLRSGFPAAAARGLGIVDVPLICAQEMDVASAMPRVVRILAHVDSGLERSEITHVYLGAAAALRKDIAQ
>NZ_CP016559.1|WP_003959940.1|5672428_5673121_-|nucleotidyltransferase
MTPEELIHEHTIYSCVMGSRAFGLATDGSDIDRRGVFLAPTALYWRFEKPPRHVEGPAEEQFSWELERFCELALRANPNILECLHSPLVERIDATGRELRELRGAFLSRQVHETFTGYALGQRRRLEGQLREGGVPRWKHAMHLLRLLASCRELLRTGELVLDVGAERERLLAVKRGEVGWPEVESWMHRTADEVERAVARSPLPAAPDRARVEDFLVRTRRASALGRPG
>NZ_CP016559.1|WP_003959941.1|5671349_5672384_+|ADP-ribosylglycohydrolase-family-protein
MTTLWTARTVTRQAATGSLIGLALGDALGFPTEFNDVPAILAKAGPWRGMDLPRPAFVSDDTQMTLAVGRAVRTAMDRGLLTGPRLTGPLRDEYIAWSRSPENNRMPGHTCMVACEQLADGRLPWLRATQIGSKGCGANMRVAPIGLVPGLSDQQRAGAAQLQSALTHGHPTALAAADLTARAIHLLVRGAQPEQLVGRLRSYAYENRTRYHEHWLGALWTLAPDPSPEAFIARGWDECLTALDRLTDALAAPDPEADPCRTTGDGWIAEEALASALHCFLLLPGEPVAALRRAACTRGDSDSIAAITGALAGAHLGADAWPKEWAERIEYRSDLLSLGALWDA
>NZ_CP016559.1|WP_003958412.1|5670537_5671353_+|NUDIX-hydrolase
MTTHQRQGVREADGRAAAARDDEEDDQEGQDGQPYDPRAFPPFAVTVDLAVLTVRDSRLQVLLVRRGESPYRGAWALPGGFVRPEESAGSAARRELAEETGLGHDTVHGLHLEQLRTYSDPGRDPRMRVVSVAYTALLPDLPEPRGGGDAAHAQWVPRDRTGPLAFDHDRILADAHDRIRAKLEYTCLATGFCPPEFTLGELQQVYETVWGVPLDRPNFRRKVLATPGFVEAVEGPPRRTGGRGKPAALYRAGPASALHPPLLRPEGRPQP
>NZ_CP016559.1|WP_003958413.1|5669201_5670332_+|rRNA-pseudouridine-synthase
MRSSGRNSGNSGGRGDRGGSGGTGAGRGNYRGAGNGRDDKQQKRTGRPRPEERRYDVGGFSGGPGGDGGGGERKGRGTAARGGAKGGPKQSQSPQRGRGGRTAPARSREYDARAEERNRERYANRPEIKTPKTFGEQEGERLQKVLARAGVGSRRACEELIEAGRVEVNGSIVIEQGVRVDPENDEIKVDGLTVATQSYLFFALNKPAGVVSTMEDPDGRQCLGDYVTNRETRLFHVGRLDTETEGIILLTNHGELAHRLTHPRYGVKKTYLAAIQGPLPRELGKRLKDGIALEDGYARADHFRVVENTGKNYLVEVTLHEGRKHIVRRMLAEAGFPVDRLVRTAFGPIGLGDQKSGWLRRLSNTEVGMLMKEVGL
>NZ_CP016559.1|WP_003959942.1|5668506_5669163_+|SMC-Scp-complex-subunit-ScpB
MSDLKPALEAVLMVVDEPATEEHLAKILEHPRRAVADALRELADEYTVQGRGFELRLVAGGWRFYSRPEHSAAVERFVLDGQQARLTQAALETLAVVAYRQPVSRSRVSAVRGVNCDGVLRTLLQRGLVEEAGTEPETGAILYRTTNHFLERMGLRGLDELPELAPFLPEADAVEAETAEGVPSFDPDAPDDHAEEGMGVLGGTADEDGRDDQHDRHD
>NZ_CP016559.1|WP_003959943.1|5667298_5668510_+|segregation/condensation-protein-A
MPPTDLPRPPRRTLGRGPGAAPETERDESCAPPEPPECPAADPVPDIPVQDIPVQDGPVPRGPVRDTPADDAPADDVPADDSDDSDGTGETGEPGWADESDGANGAAEGAPGEDRRFTVRLANFEGPFDLLLQLISKHKLDVTEVALSRVTDEFMTYIRALGDDWDLDQTTEFLVVAATLLDLKAARLLPAAEVEDEADLALLEARDLLFARLLQYRAYKQIAGILADRLDAEGRRFPRTVGLEPHHADLLPEVVISIGAEGFARLAAKAARPRPRPQLYVDHIHAPLVSVREQARIVVALLRERGRATFRELAEGTEDTLTVVARFLALLELYRDRAVALEQEDALGELIVTWTGGDGAATVTDEFDRPPDSPRDPAAGRTADTGTEQAEQAEAAEKGKDPA
>NZ_CP016559.1|WP_003959944.1|5666641_5667196_+|hypothetical-protein
MSLPGADELFRTTGGTALQPSSPRTRPTAGEPRVPAPAGESDPLETPAAGPGAQEHPASGSGGGGEGRGRAEEAPAQPASAAARGRRPQTAQPAQESAAAPARRAPRGRANRRPSGRERHDEKITVYVSAEELMDLEHARLVLRGEHGLAVDRGRIVREAVAVVLADLEQRGDASILVRRLRGR
>NZ_CP016559.1|WP_044972352.1|5665619_5666645_+|ParA-family-protein
MKMMDGLHVNATAGNESGRESTHFAAYEELPEGHFYDPDAEYEPDPEYAATLAPDAARQRRERIGPTGRPLPYFPIPGPLTDHGPAKIIAMCNQKGGVGKTTSTINLGAALAEYGRRVLLVDFDPQGALSVGLGVNPMELDLTVYNLLMERGMSADEVLLKTAVPNMDLLPSNIDLSAAEVQLVSEVARESTLQRALKPLMSDYDYIVIDCQPSLGLLTVNALTAAHKVIVPLECEFFALRGVALLTETIEKVQERLNPELELDGILATMYDSRTVHSREVLARVVEAFGDHVYHTVIGRTVRFPETTVAGEPITTYASNSVGAAAYRQLAREVLARCHAE
>NZ_CP016559.1|WP_003958407.1|5675549_5676236_+|(d)CMP-kinase
MSDTVESVIVAIDGPAGTGKSSTSRAVAAELGLSYLDTGAQYRAITWWMINNGVDVADPAAIASAAEKPAIVSGTDPDGPTITVDGADAAGPIRTQEVSSKVSAVSAVPEVRTRITELQRAIAAAAPAGIVVEGRDIGTTVLPDADLKIFLTASAEARAARRTGELKGADLAATKEALIKRDAADSSRKTSPLAKADDAVEVDTTDLTLQQVIECVVTLVREKQQATR
>NZ_CP016559.1|WP_003959939.1|5676232_5676934_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MTRAVGAPPAPGGSGRTGAAPSARGAAVGRGIGIGLMNGFWRPRILGAWRVPATGPVILAVNHTHFVDGPMLMGTAPRPVHFLIKKEAFIGPLDPFLRGIGQLKVDRSGADRSAVTGALAVLEQGGVLGIFPEGTRGEGDFASLRGGLTYFAVRSGAPVVPVAVLGGDERPGRLVKALPALGSRVDVIFGDAFHAGDGSGRRTRAALDEATAGLQRRLRAHLENARRLTGRAG
>NZ_CP016559.1|WP_009995668.1|5676993_5678442_+|ribosome-biogenesis-GTPase-Der
MNDQHDHGALGDAEYAEFMELAAEEGFDLEAVEEAIDEAGHGPLPVLAVVGRPNVGKSTLVNRIIGRREAVVEDKPGVTRDRVTYEAEWAGRRFKVVDTGGWEQDVLGIDASVAAQAEYAIEAADAVVFVVDASVGATDTDEAVVRLLRRAGKPVVLCANKVDGPSGEADAAALWSLGLGEPHPVSALHGRGTGDMLDAVLEALPEAPAQSFGTAVGGPRRIALIGRPNVGKSSLLNKVAREERVVVNELAGTTRDPVDELIELGGVTWKFVDTAGIRRRVHLQEGADYYASLRTAAAVEKAEVAVVLIDASENISVQDQRIVTMAVEAGRAMVIAFNKWDTLDEERRYYLEREIETELGQIAWAPRVNVSARTGRHMEKLVPAIETALAGWETRVPTGRLNAFLGELVAAHPHPIRGGKQPRILFGTQAGTKPPRFVLFSSGFLEHGYRRFVERRLREEFGFEGTPIQISVRVREKRGRKK
>NZ_CP016559.1|WP_009995667.1|5678529_5678910_-|hypothetical-protein
MHSYDPSRHPYGQIPAMRPARETPHDYPSAPPVTPLSTGSSTPIYEALCAEFRRAFRTLPGDRSGEEDLVFRSFGTGQYPGHHPGRGFGSGAPAPYPGTGWQPFPGPLAPVGHYPAALPPAPRRGL
>NZ_CP016559.1|WP_065757186.1|5679104_5679950_-|hypothetical-protein
MPRMLDVSEDVRAEIGDQEADRLLAGESAPSGYDCTSCRTPGDTEQECTSTVLFVGEETAVLAFAHASCIPSQVVRVAEDQLQGAVRSITGEQRSAAAPPVPAPVPGAAPDRTPPPEPAPGQAVLGITSGLILVSGALHPALVVEPTGPIARPGTDGSSGDVFLPLLIEQGFAPVHDVDRAPVPLSGWSVLLAMGQLHAVLQPGPAGGSPVAWWQAHQPLQVTEDWRTTANKTHTVLVYAAPAGSIGQQPREDLMRDALEKAAAGGRLVAAAMPLAGTGSS
>NZ_CP016559.1|WP_003959936.1|5680484_5681213_+|LysM-peptidoglycan-binding-domain-containing-protein
MVTSSRSTSGSPAPVPGARAGARGSRGAGRPGTLALAGAALIAPLVVLGAGTGTARAADAGVWDRIARCESGGNWHINTGNGYYGGLQFAPSTWRAHGGTAYAPTADRASRSQQIAVAVRVQRAQGWGAWPTCSARAGAHGSAPSVAAAPERRPATAPRSPAVRQAPAADRNRTRAVPQRATGHTSRSGERARGTAYTVRAGDTLSSIAQAHGTDWRTLHTANRQVVGADPDLIVPGQRLTL
>NZ_CP016559.1|WP_003958403.1|5681373_5682645_+|glycosyltransferase
MRISFLLHNAYGIGGTIRTTFNLARELAERHEVEIVSVFRHRENPLMGSPTGVTLRHLVDLRKNSPGYDGDHPDHRRPAKVFPRGDGRHKQYSRLTDERIAAHLAAVEADVVIGTRPGLNMHIARQTRPGPLRIGQEHLTLDGHGYRLRREIGYRYPLLDAVTTVTEADADAYRALGLPGLRIEAVPNSVPAPSVGPADTSAKYVVAAGRLTRVKRYDDLVAAFAKVAAAHPDWKLRIYGSGDRTGNERDDLAAQIEKLGLTGTVALMGNADPLEDEWVKGSIAAVTSARESFGMTIVEAMRCGLPVVSTDCPHGPREIIEDGVDGRLVPVGDIDAIAGALRELIEDDEARRRAGAAALTASERFDPARIALRHEALFTELSERADTGRPRSAARDAAFRAQGAVFDALYSARYRAASLIRRG
>NZ_CP016559.1|WP_003958401.1|5684291_5686001_-|cytochrome-c-oxidase-subunit-I
MSGTRTAAPGGERDDVRELRLVRVLVTWLTTTDHKKIGHLYLITSFGFFLIAGLLALLMRAELARPGLQLISNEQFNQAFTLHGTIMLLLFATPAFAGFANEIMPLQIGSPDVAFPRLNALAYWLYLFGGLIVLGSLLTPGGPASFGWFAYAPLNSATHTPGVGADLWIMGLALSGFGTILGAVNFITTVVGLRAPGMTMFRLPVFTWNVLFTSILVLFAFPVLAASLLVLEADRRLGAQVFEPASGGALLWQHLFWFFGHPEVYIIALPFFGIVTEILPVFSRKPVFGYLTLVGATMAITGLSVVVWAHHMFATGAVLLPFFSFMSFLIAVPTGVKFFNWTGTMLRGSLSFETPMLWSVGFLVSFLFGGLTGVILASPPLDFQVTDSYFVVGHFHYVVFGTVVFATFAGFHFWWPKFTGKMLDERLGKIHFWTLFIGFHTTFLVQHWLGAEGMPRRYADYLAVDGFTALNSVSTVGAFLLGLSTLPFLYNVWHTAKYGVKVEVDDPWGYGRSLEWATSCPPPRHNFVTLPRIRSESPAFDLHHPEYAPLRLPPLPAPPVPSSEDPARP
>NZ_CP016559.1|WP_003959933.1|5686299_5686515_+|hypothetical-protein
MGTAPRPPGHPDDATSAYVGLSAETAEQRARRRGWTTVRALPPGAIITLEYLEGRINFEVRGGEVVRCWSG
>NZ_CP016559.1|WP_009995663.1|5686687_5687728_-|phosphatase-PAP2-family-protein
MRTDIFARLDREPEPPKIEIPRMSRTRLALFGGTSAFYLAIVVAVLASTWLVIVDWKIMLFRPYQQWPSLHPFLDCFVVLGQRGPTAVMVAAWLGWRSWRQHTLRPLLVLGVSLLLLNATVGAVKIGLGRLGPHYATRIGSPELFAGGDIFPSGHTANAVVTWGILAYLATTPTTRRYLSALSATVSLGVGLTTVYLGTHWLSDVLLGWAAGLLILLALPWCEPLIGRTEAWILERRERWRARRRLAPSLPVAAGGPRPAAGAALRTPAEDAVDGVREPVGAVPPPAQGGPRPPAARKQPQRQKGGAGRSGERLTQTIPQPVRAERSAVAPAGARPAPSSRPSSGG

Crispr_ID: NZ_CP016559_18

• CRISPR_ID: NZ_CP016559_18
• CRISPR_location: 5720216-5720303
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_18

Consensus_repeat	Method
TTTTTTGTGGCTCGGTTCGCCTCCGGGGTGC	CRISPRCasFinder

spacers of NZ_CP016559_18

>18.1|5720247|26|NZ_CP016559|CRISPRCasFinder
CAGAGCGTGCGCCGACGGACGCCCCC

CRISPR arrays and Neighbor proteins around NZ_CP016559_18

CRISPR arrays

The CRISPR arrays of NZ_CP016559_18

>merge|NZ_CP016559|18|5720216-5720303|CRISPRCasFinder
TTTTTTGTGGCTCGGTTCGCCTCCGGGGTGCCAGAGCGTGCGCCGACGGACGCCCCCTTTTTTGTGGCTCGGTTCGCCTCCGGGGTGC

>NZ_CP016559|18|17|5720216-5720303|CRISPRCasFinder
TTTTTTGTGGCTCGGTTCGCCTCCGGGGTGC	CAGAGCGTGCGCCGACGGACGCCCCC
TTTTTTGTGGCTCGGTTCGCCTCCGGGGTGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_009995646.1|5714506_5714935_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|274679
NZ_CP016559.1|WP_003957505.1|5719823_5720201_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224639
NZ_CP016559.1|WP_003957513.1|5727699_5729193_+|citrate:proton-symporter	unknown	unknown	gnl|CDD|225407
NZ_CP016559.1|WP_003957517.1|5730851_5731352_+|redox-sensitive-transcriptional-activator-SoxR	unknown	unknown	gnl|CDD|133385
NZ_CP016559.1|WP_003959901.1|5726002_5727361_-|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|235421
NZ_CP016559.1|WP_003957514.1|5729510_5730140_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380061
NZ_CP016559.1|WP_003957506.1|5721026_5722133_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|99707
NZ_CP016559.1|WP_003959914.1|5712587_5713565_-|lytic-polysaccharide-monooxygenase	unknown	unknown	gnl|CDD|376983
NZ_CP016559.1|WP_029182860.1|5723615_5723879_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957503.1|5717597_5719091_+|tripartite-tricarboxylate-transporter-TctA	unknown	unknown	gnl|CDD|225870
NZ_CP016559.1|WP_078564411.1|5710117_5710984_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP016559.1|WP_003959903.1|5723959_5725204_-|CoA-transferase	unknown	unknown	gnl|CDD|224717
NZ_CP016559.1|WP_003957516.1|5730225_5730687_-|MaoC-family-dehydratase	unknown	unknown	gnl|CDD|239534
NZ_CP016559.1|WP_003957500.1|5716053_5717037_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270234
NZ_CP016559.1|WP_003957501.1|5717033_5717594_+|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl|CDD|377815
NZ_CP016559.1|WP_003959915.1|5711205_5712303_-|hypothetical-protein	unknown	unknown	gnl|CDD|274414
NZ_CP016559.1|WP_003957504.1|5719164_5719665_-|DUF402-domain-containing-protein	unknown	unknown	gnl|CDD|377233
NZ_CP016559.1|WP_003959906.1|5722413_5723223_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238861
NZ_CP016559.1|WP_003957510.1|5725200_5725953_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP016559.1|WP_003959911.1|5715236_5715926_-|response-regulator	unknown	unknown	gnl|CDD|226931

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_009995646.1|5714506_5714935_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	1.49287e-11
NZ_CP016559.1|WP_003957505.1|5719823_5720201_+|GntR-family-transcriptional-regulator	gnl|CDD|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	9.45541e-23
NZ_CP016559.1|WP_003957513.1|5727699_5729193_+|citrate:proton-symporter	gnl|CDD|225407	COG2851, CitM, H+/citrate symporter [Energy production and conversion].	4.24617e-85
NZ_CP016559.1|WP_003957517.1|5730851_5731352_+|redox-sensitive-transcriptional-activator-SoxR	gnl|CDD|133385	cd01110, HTH_SoxR, Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator. Helix-turn-helix (HTH) transcriptional regulator SoxR. The global regulator, SoxR, up-regulates gene expression of another transcription activator, SoxS, which directly stimulates the oxidative stress regulon genes in E. coli. The soxRS response renders the bacterial cell resistant to superoxide-generating agents, macrophage-generated nitric oxide, organic solvents, and antibiotics. The SoxR proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the unusually long spacer between the -35 and -10 promoter elements. They also harbor a regulatory C-terminal domain containing an iron-sulfur center.	1.00399e-75
NZ_CP016559.1|WP_003959901.1|5726002_5727361_-|homogentisate-1,2-dioxygenase	gnl|CDD|235421	PRK05341, PRK05341, homogentisate 1,2-dioxygenase; Provisional.	0
NZ_CP016559.1|WP_003957514.1|5729510_5730140_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	2.3212e-34
NZ_CP016559.1|WP_003957506.1|5721026_5722133_-|AAA-family-ATPase	gnl|CDD|99707	cd00009, AAA, The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.	2.37512e-08
NZ_CP016559.1|WP_003959914.1|5712587_5713565_-|lytic-polysaccharide-monooxygenase	gnl|CDD|376983	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading. This domain is found associated with a wide variety of cellulose binding domains. This is a family of two very closely related proteins that together act as both a C1- and a C4-oxidising lytic polysaccharide mono-oxygenase, degrading cellulose. This domain is also found in baculoviral spheroidins and spindolins, protein of unknown function.	6.09565e-66
NZ_CP016559.1|WP_003957503.1|5717597_5719091_+|tripartite-tricarboxylate-transporter-TctA	gnl|CDD|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_CP016559.1|WP_078564411.1|5710117_5710984_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.86131e-18
NZ_CP016559.1|WP_003959903.1|5723959_5725204_-|CoA-transferase	gnl|CDD|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	2.33082e-130
NZ_CP016559.1|WP_003957516.1|5730225_5730687_-|MaoC-family-dehydratase	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	1.67248e-90
NZ_CP016559.1|WP_003957500.1|5716053_5717037_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	3.94597e-84
NZ_CP016559.1|WP_003957501.1|5717033_5717594_+|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl|CDD|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	4.59836e-13
NZ_CP016559.1|WP_003959915.1|5711205_5712303_-|hypothetical-protein	gnl|CDD|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	1.93629e-06
NZ_CP016559.1|WP_003957504.1|5719164_5719665_-|DUF402-domain-containing-protein	gnl|CDD|377233	pfam04167, DUF402, Protein of unknown function (DUF402). Family member FomD is a predicted protein from a fosfomycin biosynthesis gene cluster in Streptomyces wedmorensis. Its function is unknown.	4.70128e-18
NZ_CP016559.1|WP_003959906.1|5722413_5723223_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	1.63999e-54
NZ_CP016559.1|WP_003957510.1|5725200_5725953_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	5.48488e-42
NZ_CP016559.1|WP_003959911.1|5715236_5715926_-|response-regulator	gnl|CDD|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.05832e-71

Protein sequences

>NZ_CP016559.1|WP_003957505.1|5719823_5720201_+|GntR-family-transcriptional-regulator
MTLKIVIDAASATAPFEQLRTQISERARSGALPVGYRLPTVRGLAEELGLAANTVAKAYRALEADGVVETRGRNGTFVAAAQGAGARELAAAAKSFAERARRLGADRDTAHAAARDAIRAVYGDD
>NZ_CP016559.1|WP_003957504.1|5719164_5719665_-|DUF402-domain-containing-protein
MTAPPTVTVRLLKAGREKVVYRAALLTDDGTHIVVRAPWTIPVRDLGFVRFEPGDVFTEHFWRDRWYAVKEVRTGDGALKGWYCDIALPARLTGAELVSEDLELDLWVSGDGTSVLRLDEDEFAASGLAERDPEAAGRARAALDELEALVRAGRLGELLERPGGAR
>NZ_CP016559.1|WP_003957503.1|5717597_5719091_+|tripartite-tricarboxylate-transporter-TctA
MDSLNSLIDGFGTALTPINLLWAVIGVLLGTAIGVLPGIGPAMAVALLLPVTYGLEPTGAFIMFAGIYYGAMFGGSTTSILLNTPGESAAVVAAIEGNPMAKSGRGSQALAAAAIGHFTGGLIGTLLLVALAPTVAELAVDIGAPDYFAIMVLAFIAVTSVLGSSRIRGLASLLIGLTIGLIGLDSMTGQQRLTFGNLHLADGVDVVIVAVGLFAIGEALWVAAHLRRGATAPIPVGRPWLGKDDVKRTWKPWLRGPFIGFPFGAIPAGGAEIPTFLSYVTEKRLSKNKKEFGKGAIEGVAGPESAASASASGTLVSMLTLGLPTTAVAAVMLAAFQQYGIQPGPLLFEREPDLVWGLIASLFVGLVLLLALNLPLAPVWAKLLRIPRPYLYAGILFFAGVGAYAVGGEALDLVILLIIGLLGFGMRRYGLPVLPAVIGVILGPSAEQQLRRALQISDGSVTGLVNTPFSVTVYVIIAILLAWPLLKKLVVRRRSHS
>NZ_CP016559.1|WP_003957501.1|5717033_5717594_+|tripartite-tricarboxylate-transporter-TctB-family-protein
MNSQETPATPTEQTSTGPGAASRGSWLRERSELGVGVLLFAIGVLVLGDALTMDVDIAQRGPVGPRTVPIAVGIGLLVIAVLLAVDVLRGGRGEAESGEDIDLSEPSDWRTVLLLAGVFLGFAVLIGPLGFPISGMLLFWGAAFALGSRSFDRDPLIAATLSLVTYYLFNNLLGVPLPGGPLMGVL
>NZ_CP016559.1|WP_003957500.1|5716053_5717037_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MRLRTPLAVLGAALLVFVGPPLLSEGESSDSGTRIPGLRIMVPNTPGGGYDITARTAAKNAEDADLTSDIEVFNLPGAGGTVGLAQLVNERGNGKLAMSMGLGVVGAVHTNKAPKTLADTTPIARLTEEQDIVVVSKDSPYKSIQDLVTAWKKNPGKLPVGGGSSPGGPDHLAPMLMAQAAGIAPKTVNYIPFDGGGELLASILGNKVAFGVSGVGEYLDQIKAGELRLLAVTGPERVPGLDAPTLREAGIDTEFTNWRGIVAPPGLTDAERDKLVTLVEKLHASPQWKESLKKHGWNDAFLTGEKFGDFLDEQDKRVDSVLKELGL
>NZ_CP016559.1|WP_003959911.1|5715236_5715926_-|response-regulator
MNVLVVDDDFMVAKLHSRYVASTAGFRVAGVAHSGAEALSAAERLRPDLVLLDIYLPDMDGLMVLRELRAAEALDTARPSADALFITAARDAGLVRAALRAGALHYLIKPFNQSALQEQLRHVAALRSRFDRLGEARQEDVDQIFGTRPPGSRELPKGLAAHTAELVERILREHRGDLSATECAEAGSLSRVSARRYLEYFAETGRVEVSLRYGGTGRPERRYRLVGGG
>NZ_CP016559.1|WP_009995646.1|5714506_5714935_+|pyridoxamine-5'-phosphate-oxidase
MTLTREERQQFLAEPHIAALAVNAGDDGRAPLTVPVWYHYAPGRDVWIMTGLGSRKERLIARAGRFSLLVDRERPTVRYVSVEGPVVGTCPATRRHVAEISARYLPARKVASYVEFVEKELGDQVIIQMRPQRWNSADLGPV
>NZ_CP016559.1|WP_003959914.1|5712587_5713565_-|lytic-polysaccharide-monooxygenase
MTTRRTAAVAAALGVVPLALTALTVTPAAAHGSMLDPVSRVSACFAEGPESPDSAACKAMVAAGGTQPLYDWNEVNIGDAAGRHRQIIPDGKLCSVGRDKYKGLDAPRADWPSSPMAAGSKTFRWRATAPHRGTLELYITREGYDPTKPLKWSDLEAQPFAKVTDPRLENGSYVFDGQVPNRTGRHLIYSILQRSDSPEAFYTCSDVVFGGKAPAGAPAAQAPSENAIEQGAGNSSVDHGGHGGDTAAEKKANAEHVAQRTGGGNAPQTQVAHTTELAATSEQALAETGGDSTSMYIAIGGAAALALGAAGMFASARRRAGGSAI
>NZ_CP016559.1|WP_003959915.1|5711205_5712303_-|hypothetical-protein
MKRTSDGPPDGASTAGPAAPTGFLAEVRDAVSVRAALLVIGVLLLQLAFITSYIGAFHEPRPHEVPLAVAAPDPLTTAGTVRGLAALPGDPLDPRAVADEAEARRQIENRDVDGALIVDPRGTTDRLLVASAAGASLADALAGAVGAAEQRQGRTVRVTDVVPNAAGDARGLSSFYLVIGWCVGGYLCAAVLAISAGARPANIHRALIRLGVLLLYSIAAGLLGTVIAGPVLQALPGGVAPLWGLGTLLVFTVGAITLALQGLLGIVGIGLAIALVVVLGNPSAGGAYPWPMLPPFWSAIGPALPPGAGTFAARSISYFHGHAVGGPLLVLAAWAVAGSVVTLVCATARTLTGDRPAAPAGTTAP
>NZ_CP016559.1|WP_078564411.1|5710117_5710984_-|alpha/beta-hydrolase
MRHRVRTSDGRHLMVERLGDPHGRPVFLLHGTPGCRLGPAPRGMVLYQRRTQLIAYDRPGYGGSDRLPGRSVADVARDVRDIADELGLDRFAVVGRSGGAPHALACAALLPERVTRAAALVTLAPRDAAGLDWFEGMAASNVLEYTFASDHPDVLTERFILRSAQIREDPIRLLNDLRKELTESDRMVVQDAGVRGMLLRNYQEALRTSAYGWIDDALAFSSPWGFDPADIKAPVMLWHGEKDVFSPVGHSRWLAERIPGATAVLEPSAAHFDALHALPRALTWLVEE
>NZ_CP016559.1|WP_003957506.1|5721026_5722133_-|AAA-family-ATPase
MATAPVPPQHAVPVRITLDDNDSPTDVIDALFLGRFTSGEQPYAHGHQVERVKRDADLLPPGARVLRSARDDDRRAVLAEGEGFTVLVSHWNRGADVTVTAVSAELAERIVKESTADAEDEPEPEPDDVTMGFWYVSPRRGPYRTTRPISAGPWEEIRRNYTAPVAEAMDRLMKVTPDDIAGRLLLLHGPPGTGKTSALRTLARSWQDWCQVDCVLDPERLFSDVGYLMDIAIGEDDESTGKERWRLLLLEDCDELIRGEARHMAGQALSRLLNLTDGLLGQGRNVLVGVTTNEDLERLHPAVVRPGRCLARIEVGPLTHAESVGWLGREEGVGRQGSTLAELYALRRGTGPASVPGQNDGADAGLYL
>NZ_CP016559.1|WP_003959906.1|5722413_5723223_+|SGNH/GDSL-hydrolase-family-protein
MKLSRITAFSSSLLLGAALALTGAAQAQAAENAAPVDYVALGDSYSSGLGAGGYDSASGDCKRSNRAFPKLWAAANSPSSFGFTACAGAITSDVTSKQLGPVNASTDLVSISVGGNDAGFADVMTTCVLQSEANCINRVNQARAFVDATLAGRLDSVYNAISSRAPSARVVVLGYPRFYQLNGGCLAGLSENERRAINGGADHLNTALAKRAANHGFDFADVVPHFTGHEICSGDSWLHSVNWLNIGESYHPTASGQSGGYLPAFRSRA
>NZ_CP016559.1|WP_029182860.1|5723615_5723879_+|hypothetical-protein
MERITVRSRPRVPAITCGSQATSSRLDRHLSVLGGPAVPQRDAVEATSLMRELTSRDVRHDRDRGKGGVALFAPLRRLRRSLFGSRR
>NZ_CP016559.1|WP_003959903.1|5723959_5725204_-|CoA-transferase
MSRADGTRGGGPAQPPRPPQPLPLEGITVVAVEQAVAAPFATRQLGDLGARVIKVERPDGGDFARGYDTAARGLASHFVWCNRGKESVAVDLKDPRGLALVRRLIADADVFVQNLAQGAAARLGLDAATLCAGHPRLVAVDISGYGAGGPYAHRRAYDMLVQCEAGLVSVTGTAEHPAKAGIPAADIAAAMYAFSGVLAALLRRGVSGRGGPVEVSMLDALAEWMGHPLHHGMHGGEPPARTGVAHAVIAPYDAYPTADGGQVLLSVQNDREWRRLAERVLERPELADDPRFASNRARTLHRARTDEAVAGALGRLTAAEAVERLDAAGIACARLNSVADVVAHPQLAARDRWRETPSPAGPLRALLPPIGLPGGPEPRMGAVPALGEHTEAVLRSLGVTEAESLALRRDGVVA
>NZ_CP016559.1|WP_003957510.1|5725200_5725953_-|GntR-family-transcriptional-regulator
MTSSFAPDSVVLNRKLPLWYQVSQSLRASILGRGPDASLRLPTEEQLAAHYGVSVLTMRQALKELEEEGLISRHRRRGTFIEPGARRCAPRRLLGSIDAIVAQQSGERTAVLGHGPVPVPGEIAEHFPGLTEVVTYRRLRSDGESGEPTNWAENAVRPDVAARLDVADLERWPMTKVLRDAVGVRISRITDTVEARLADPVTAHLLQVPLLSPILHYTGVTYDEDGRVVDVARIHYRGDRFSFSVTVAAE
>NZ_CP016559.1|WP_003959901.1|5726002_5727361_-|homogentisate-1,2-dioxygenase
MSGIERARQTTEAMERARKTAEGLGYSPGFGNEHSSEAAPGALPVGRNSPQRAPLGLYAEQLSGSAFTEPRAHNRRTWLYRIRPSAAHPPLHRIDNGALRGAPFTETVPDPNRLRWDPLPEPAPGTDWLAGLWTLGGNGDAARRTGMAVHLYHANAPMTGRVFGDADGELLIVPELGGLLLVTELGALAARPGEVALIPRGVRFRVELLDERARGYVCENHGRPFVLPDLGPIGANGLANARDFRAPVAAYEDRTEPVEVVTKFCGNLWAAEYDHSPLDVVAWHGNHVPYVYDLRRFNAIGSISYDHPDPSIFTVLTSPSDTPGLAGVDFVAFVPRWLVGEDTFRPPYFHRNVMSEYMGLIEGAYDAKSAGAGGFVPGGGSLHNMMSAHGPDRETFDRASAATLRPQKIDDGLAFMFETRWPLTATARAAGADHLQKGYDGVWQGLERHFPS
>NZ_CP016559.1|WP_003957513.1|5727699_5729193_+|citrate:proton-symporter
MLTILGFAMIATFLVLIMMKKMSPIAALVLIPALFCVLVGKGAELGDYVIEGVGNLAPTAAMLMFAIVYFGVMIDVGLFDPIVRAILRFCKADPMRVVVGTALLAAIVSLDGDGSTTFMITVSAMYPLYKRLKMSLVVMTGIAATANGVMNTLPWGGPTARAATALKLDAADIFVPMIPALAVGLLFVFILAYVLGLRERKRLGYLSLDEVLSSEQGDALVKVGGGAKAASGAGKGAKNKGAKGKGKGAGGAKGAGQAAGSGSSGTGTGSDEDAVDGPAQVEEGFQGLDPNRPTLRPKLYWFNAGLTIALLTAMIMELLPIPVLFLLGAALALTVNYPNMAEQKARIGAHAENVLNVAGMVFAAAVFTGVLTGTGMVKSMADWLVGAVPEGMGPHMAIVTGLLSLPLTYFMSNDGFYFGVLPVLAEAGAAHGVSPLEIARASLVGQALHMSSPLVPAVYVLVGMAKVEFGDHTRFTVKWAALTSLVVLAAGVAFGII
>NZ_CP016559.1|WP_003957514.1|5729510_5730140_+|TetR/AcrR-family-transcriptional-regulator
MGTADDTTGDEVPWGEVTPEAARKLLVAAVEAFAERGYHATTTRDIAGRAGMSPAALYIHYRTKEELLHRISRIGHERALEVLETAAARPGTPGERLADAVSSFVRWHAWRHDTARVVQYELDALSPEHRTEIVELRRRSGAVLRGVLREGVESGEFDVPDLPGTTLAVLSLCIDVARWFNTRGARTPEEVGALYADLVLRMVAARPAV
>NZ_CP016559.1|WP_003957516.1|5730225_5730687_-|MaoC-family-dehydratase
MAGPRIFTSADELRAAVGEQLGHSDWLEIDQRRIDLFAEATGDHQWIHVDAGRAAEGPFGTTIAHGYLTLSLLPALVPQVMRVEGVTMGINYGTDKVRFPAPVPVGSRLRATAVLTEVREAGGGVQVTTAVTVEREGGEKPVCVADSVSRYYF
>NZ_CP016559.1|WP_003957517.1|5730851_5731352_+|redox-sensitive-transcriptional-activator-SoxR
MPDSTDQIKELTVGQLSARSGAAVSALHFYEAKGLISSRRTSGNQRRYTRDTLRRVAFVRAAQRVGIPLATIRDALAELPDERTPDREDWARLSRTWRRELEDRITQLHRLRDHLTECIGCGCLSLETCVLSNPDDTFGRSMAGSRLMPVRYPEQGPEPGRGRSGG

Crispr_ID: NZ_CP016559_19

• CRISPR_ID: NZ_CP016559_19
• CRISPR_location: 6441379-6441458
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016559_19

Consensus_repeat	Method
CCGGAGGCGAACCGAGCCACAAAAA	CRISPRCasFinder

spacers of NZ_CP016559_19

>19.1|6441404|30|NZ_CP016559|CRISPRCasFinder
GGGGCGTCCGTCGGCAGACGCTTCAGCGTC

CRISPR arrays and Neighbor proteins around NZ_CP016559_19

CRISPR arrays

The CRISPR arrays of NZ_CP016559_19

>merge|NZ_CP016559|19|6441379-6441458|CRISPRCasFinder
CCGGAGGCGAACCGAGCCACAAAAAGGGGCGTCCGTCGGCAGACGCTTCAGCGTCCCGGAGGCGAACCGAGCCACAAAAA

>NZ_CP016559|19|18|6441379-6441458|CRISPRCasFinder
CCGGAGGCGAACCGAGCCACAAAAA	GGGGCGTCCGTCGGCAGACGCTTCAGCGTC
CCGGAGGCGAACCGAGCCACAAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016559.1|WP_003959440.1|6452005_6453247_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133058
NZ_CP016559.1|WP_003957665.1|6434621_6435980_+|membrane-protein	unknown	unknown	gnl|CDD|379080
NZ_CP016559.1|WP_003959442.1|6442535_6443228_-|DUF305-domain-containing-protein	unknown	unknown	gnl|CDD|367619
NZ_CP016559.1|WP_003959444.1|6438182_6439199_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957670.1|6441478_6442342_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_009995277.1|6439191_6440529_-|DUF2252-domain-containing-protein	unknown	unknown	gnl|CDD|313268
NZ_CP016559.1|WP_003957676.1|6447387_6448056_-|hypothetical-protein	unknown	unknown	gnl|CDD|225512
NZ_CP016559.1|WP_003957674.1|6445143_6446139_-|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238042
NZ_CP016559.1|WP_003957664.1|6434288_6434591_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957662.1|6431300_6433085_-|nickel-dependent-hydrogenase-large-subunit	unknown	unknown	gnl|CDD|380187
NZ_CP016559.1|WP_003957667.1|6437627_6438224_+|DUF4240-domain-containing-protein	unknown	unknown	gnl|CDD|379426
NZ_CP016559.1|WP_029182819.1|6430006_6430675_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957675.1|6446257_6447391_-|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|223513
NZ_CP016559.1|WP_003957666.1|6436036_6437113_-|chitinase	unknown	unknown	gnl|CDD|119350
NZ_CP016559.1|WP_003957663.1|6433202_6434285_-|hydrogenase-expression-protein-HypE	unknown	unknown	gnl|CDD|224654
NZ_CP016559.1|WP_009995281.1|6430830_6431304_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957672.1|6443320_6443890_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016559.1|WP_003957673.1|6444017_6444701_-|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_CP016559.1|WP_003957677.1|6448247_6449276_-|hypothetical-protein	unknown	unknown	gnl|CDD|381626
NZ_CP016559.1|WP_003959441.1|6449493_6451374_-|DUF2334-domain-containing-protein	unknown	unknown	gnl|CDD|200549

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016559.1|WP_003957665.1|6434621_6435980_+|membrane-protein	gnl|CDD|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	2.71275e-05
NZ_CP016559.1|WP_003959442.1|6442535_6443228_-|DUF305-domain-containing-protein	gnl|CDD|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	2.08342e-50
NZ_CP016559.1|WP_009995277.1|6439191_6440529_-|DUF2252-domain-containing-protein	gnl|CDD|313268	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252). This domain, found in various hypothetical bacterial proteins, has no known function.	4.78977e-168
NZ_CP016559.1|WP_003957674.1|6445143_6446139_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	7.09522e-09
NZ_CP016559.1|WP_003957676.1|6447387_6448056_-|hypothetical-protein	gnl|CDD|225512	COG2964, COG2964, Uncharacterized protein conserved in bacteria [Function unknown].	2.56229e-37
NZ_CP016559.1|WP_003957662.1|6431300_6433085_-|nickel-dependent-hydrogenase-large-subunit	gnl|CDD|380187	NF033181, NiFeSe_hydrog, nickel-dependent hydrogenase large subunit. Members of this family are the large subunit of the periplasmic nickel-dependent hydrogenase. Some members contain a selenocysteine residue.	2.49538e-74
NZ_CP016559.1|WP_003957667.1|6437627_6438224_+|DUF4240-domain-containing-protein	gnl|CDD|379426	pfam14024, DUF4240, Protein of unknown function (DUF4240). This presumed domain is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 169 and 263 amino acids in length. This domain is often associated with the WGR domain pfam05406.	2.28669e-43
NZ_CP016559.1|WP_003957673.1|6444017_6444701_-|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	5.98693e-49
NZ_CP016559.1|WP_003957675.1|6446257_6447391_-|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|223513	COG0436, COG0436, Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism].	2.87093e-76
NZ_CP016559.1|WP_003957666.1|6436036_6437113_-|chitinase	gnl|CDD|119350	cd02871, GH18_chitinase_D-like, GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus.	1.87008e-102
NZ_CP016559.1|WP_003957663.1|6433202_6434285_-|hydrogenase-expression-protein-HypE	gnl|CDD|224654	COG1740, HyaA, Ni,Fe-hydrogenase I small subunit [Energy production and conversion].	4.37064e-53
NZ_CP016559.1|WP_003959440.1|6452005_6453247_+|glycosyltransferase-family-2-protein	gnl|CDD|133058	cd06436, GlcNAc-1-P_transferase, N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1,6-N-acetyl-D-glucosamine. N-acetyl-glucosamine transferase is responsible for the synthesis of bacteria Poly-beta-1,6-N-acetyl-D-glucosamine (PGA). Poly-beta-1,6-N-acetyl-D-glucosamine is a homopolymer that serves as an adhesion for the maintenance of biofilm structural stability in diverse eubacteria. N-acetyl-glucosamine transferase is the product of gene pgaC. Genetic analysis indicated that all four genes of the pgaABCD locus were required for the PGA production, pgaC being a glycosyltransferase.	1.8609e-81
NZ_CP016559.1|WP_003957677.1|6448247_6449276_-|hypothetical-protein	gnl|CDD|381626	cd19608, GH113_mannanase-like, Glycoside hydrolase family 113 beta-1,4-mannanase and similar proteins. Mannan endo-1,4-beta mannosidase (E.C 3.2.1.78) randomly cleaves (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans and is also called beta-1,4-mannanase, endo-1,4-beta-mannanase, endo-beta-1,4-mannase, beta-mannanase B, beta-1, 4-mannan 4-mannanohydrolase, endo-beta-mannanase, beta-D-mannanase, 1,4-beta-D-mannan mannanohydrolase, and 4-beta-D-mannan mannanohydrolase. (1->4)-beta-linked mannans are polysaccharides with a linear polymer backbone of (1->4)-beta-linked mannose units (in plants and fungi) or alternating mannose and glucose/galactose units (glucomannan in plants and fungi, and galactomannan and galactoglucomannan in plants), such as in the hemicellulose fraction of hard- and softwoods. Complete degradation of mannan requires a series of enzymes, including beta-1,4-mannanase. According to the CAZy database beta-1,4-mannanases are grouped into various glycoside hydrolase (GH) families; GH family 113 beta-1,4-mannanases include mostly bacterial and archaeal sequences.	1.36509e-105
NZ_CP016559.1|WP_003959441.1|6449493_6451374_-|DUF2334-domain-containing-protein	gnl|CDD|200549	cd10923, CE4_COG5298, Putative NodB-like catalytic domain of uncharacterized proteins found in bacteria. This family corresponds to a group of uncharacterized bacterial proteins with high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily. Some family members contain an additional copper amine oxidase N-terminal domain.	2.26075e-78

Protein sequences

>NZ_CP016559.1|WP_009995277.1|6439191_6440529_-|DUF2252-domain-containing-protein
MATPGERASRGKDRRKAVPRSSLGAWIPHADRPDPLRMLSEQEADRVQELLPVRHGRMAASPFAFLRGAAAVMAADLAARPRTGLTVQLCGDAHPLNFGMYASPERALLFDLNDFDETLPGPFEWDVERLAAGAAVAALEHGHSATAARRAAVTAAQEYRRTMRTLALAGELAVWYARIDTAELLPLIRPGNRPMAEAQFARARRRTSLQALGKLTEVVDGKRRFRPEPPLISPVDALDRSTVRAIFGEYRASLPEDRRMLLDAFRVVDVAAKVVGVGSVGTRCFVALLTGRDADDPLFLQVKEAGPAVLERWLPPSAHGHHGHRVVAGQRLLQSASDIFLGWVTGPTGRHFYWRQLRDMKGSVDLAGMSAETTARYAGLCGTALAQAHARTGDRIAIAAYLGGGDVFDRAIGEFAVRYADQNARDHTALVSAIASGDLAATSGV
>NZ_CP016559.1|WP_003959444.1|6438182_6439199_-|hypothetical-protein
MSEPPRPPGPAPGAPDGPRPPRDVPPERPLLRAVLADPHHLPEHLAWFALRHMGPAADHALVRLRERHPDADTARLRALVAAHGRRSTVAEGSLVGGPFLLLVPLAFCAALLNQARTVLELAGLDGRDPTSPERAAELLVLMGVYEDTARARTALATIADTAPVPRRALLRPRPLWDVTLRMARLLGLLTPPGQAEGGRSRRRLVLQSVRWAVTGAVFALSLVAPLVLLPYMAVSYHRATERLTDRAALFYFSEPPSARGSRVPGLSAAVLRAVLSLLLPAGLVVLVLLLGLRLWDSPWPAAVVALFGASVAVGAFWHLLRRLRRSRPVLPVGDEDGE
>NZ_CP016559.1|WP_003957667.1|6437627_6438224_+|DUF4240-domain-containing-protein
MTMDIAAAHETLPLDDFWQLIDAARERATEERPFAQALTDILADCPPQTILAYERTFTDVHERLYRWDVWAAAFLIGGGCSDDSFMDFRAGVISQGREWYERVLASPDSLARHPLALDGDPGHLENLFDERVNYAAAKAYPRALGDPEAWDAMVAEGYDADEPEEDTMGEAFDFGDEREMRRRLPSLTVLIADGEDRP
>NZ_CP016559.1|WP_003957666.1|6436036_6437113_-|chitinase
MIHRTLRLLGAGLALAFLAQLPATAAAAPASPVPPRADRAETCAVKSKPAGKVLQGYWENWDGAANGVHPPLGWIPITDPRIRAHGYNVLNAAFPVIRSDGTVLWENGMDTTVKVPTPAEMCQAKADGQTILMSIGGAAAGIDLSSRAVADRFIATIVPILKRFNFDGIDIDIETGLVGTGNINQLSASQANLIHIIDGVLAQMPPNFGLTMAPETAYVTGGSVVYGSIWGSYLPIIKKYADNGRLWWLNMQYYNGSMYGCSGDSYAAGTVAGFRAQTDCLNRGLVIQGTTIRVPYDKQAPGLPAQPGAGGGHMAPGLVTQAWNGYGNALKGLMTWSLNWDGSRNWTFGDNVRALQGR
>NZ_CP016559.1|WP_003957665.1|6434621_6435980_+|membrane-protein
MAHQTHREDLPPTVAVPLPRRLGEISRRRGATAAAARTARACGTAPGAAGRHGTPATAPPGRDRGARGARGGRDTAAPPGPARLARTVWTVVGVHAVSTAVHLLILALLNPPGGPRLKDRLLAWDALLYLSIATDGYPRGLSYTPEGSLTGNNLAFFPLYPQLVRLLHRSTGTDAGTAAIALSHLALLAALFATYALLTRLYGERVAVIGSVLLAGAQPMALTFLMGYSEALFLALATATLLAAHRGAWLTAGVLTLLAGLTRPAAGAVALALIAAVVLEIRRTGRLDWRPVTAVVVGCSGTPAYLLWVGNRVGQLNGWFVIQEAGWGTHWDSGAAFLRFLLDTFRAADGWVALSTALLLLAAVCATAVAWRRGVWPPLLVYGTTVVVLTLGQSNYYHSKLRLIVPALVFLVPPALALARARTRTAVAVLAAATLFGSWYGAHMLTVWRYAI
>NZ_CP016559.1|WP_003957664.1|6434288_6434591_+|hypothetical-protein
MSPRFRDARDASEERRLHNGHNTLFRHMSGWGAPLGSLGKPHSGGAVRATRSRLPPSARPRLPPSRSGRPAPGSHRRAPGGPPPRCDPSLSGQPGTRRRA
>NZ_CP016559.1|WP_003957663.1|6433202_6434285_-|hydrogenase-expression-protein-HypE
MSDTGTTTAKAEGPHGAADSDVVHILWINAGLSCDGDSVALTAAMQPSIEEIVTGALPGLPKVAVHWPLIDFECGPVQGADTFIEWFFKGERGELDPFVLVVEGSIPNEQIKQEGYWCGFGDDPRTGQPITTSEWLDRLAPQATAIVAIGTCATYGGIHAMAGNPTGAMGVPDYLGWDWTSKAGLPIVCVPGCPIQPDNLAETLTYLLYQLAGSAPMIPLDDKLRPAWLFGATVHEGCDRGGYYEQGQFATEYGTPECLVRLGCWGPVVKCNVTKRGWLGGVGGCPNVGGICIACTMPGFPDKFMPFMDPPPGSLVSSDASSAYGSVIRRLRSITLRTVDKEPKWRHPGDRLTTGYRTPW
>NZ_CP016559.1|WP_003957662.1|6431300_6433085_-|nickel-dependent-hydrogenase-large-subunit
MAPTTKAAGDGSGLMEMSWDPITRIVGSLGIHTKIDFKAKRVAECYSTSSVFRGYSVFMRGKDPRDAHFITSRICGICGDNHATCSVYAQNMAYGVKPPHLGEWIINLGEAAEYMFDHNIFQENLVGVDYCEKMVKETNPGVLEQAERTEAPHAGDHGYRTIADIMRALNPIEGEFYREALQVSRYTREMFCLMEGRHVHPSTLYPGGVGTVATVQLFTDYLTRLMRYVEFMKKVVPLHDDLFDFFYEALPGYEEVGRRRVLLGCWGSLNDPDHCDFTYRRMTDWGRKMFVTPGVVVDGKLVTNDLTEINLGIRILLGSSYYEDWEGRDLFVARDPLGNPVDPRHPWNQHTIPAPQKRDFDDKYSWVMSPRWFDGKDHLALDTGGGPIARLWSTALSGLVDIGYIKATGHSVRINLPRSMTKPEATFEWKIPAWSNAIERNRARTYFQAYAAAAALHFTEKALEEVRAGRHKTWERFEVPDESIGCGFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNASVRDSYGTPGPYEDAVQNTPIFEENPPENFKGIDIMRAVRSFDPCLPCGVHMYVGGGRTLQRMHVPTGLSGLGG
>NZ_CP016559.1|WP_009995281.1|6430830_6431304_-|hypothetical-protein
MTAEETGARVQRALDRLTDDTAREAGEELVRALLALHGDGLDRLVRALPQGALGRALDDPAVAGLLTLHDLHPEPVGTRIGRALDATGAGRVERTGFDPATGTLTLRREGRGCGARPEDVENALACHAPEVTAVVWEREESERPLLQIGSRPPAEAR
>NZ_CP016559.1|WP_029182819.1|6430006_6430675_-|hypothetical-protein
MLRGLRRTPAVRPERCGLCSQRVDDGHRHLADTAARALVCVCIACALLFERPDGQREGQREGQPERQEQGRAPAQGRYLPLPDRCLTDPGHEPDEAAWTALRIPVSTAFVLDNTALGRRILCYPSPAGATEAERDEDAWRAAFGNSRLAAVLRPDVEALLLRRTGDRIRCLLVPVDVCYELVGRMRLRWRGFDGGAEANADLDAFFADLAERAEPLPKETVA
>NZ_CP016559.1|WP_003957670.1|6441478_6442342_-|hypothetical-protein
MTKRRTLITAGVSAVALALTLTACADDGGDPGSSTAISHIHGVEIGPADGKLYVATHNGIYTPDKDGKPSLVGDRKDDFMGFTTAGKSRFLASGHPAPGRDAPSNLGLIESTDTGRTWKDRSLSGEVDFHSLVHAHDTIYGYDSTNGLLRVSKDGENWDNRSKLAALDLAVSPGDPETVLATTESGVSRSTDGGRTFAPGAGPVLAFISWTAEDALYGVDPKGTVSVSADGGKSWKKTGTLPGGGPQALTAVDGKRLVAASQDGVYESTDGGTDFTRRLDVTPDDAH
>NZ_CP016559.1|WP_003959442.1|6442535_6443228_-|DUF305-domain-containing-protein
MTASPRPSRGAVLRRRGALLAAVVAAGLTLAACGGDDDMAGMDHGGTQSSAAGPASPDAAAGSGSGANPAPGAFNDTDVMFAQMMIPHHEQALEMSALADGRAEDTEITALAREISGAQDPEIQKMTSWLRAWGKPGTAPMDHGSGHGSESGGMARMMSAKDLAGLKAAQGRAFDRAFAQLMIDHHKGAVEMAEDERKNGRNATARQLAEDVITTQSAEIARLEKILARL
>NZ_CP016559.1|WP_003957672.1|6443320_6443890_-|hypothetical-protein
MRARRWTRAAGAWGHLLLVAVLALGVFAMHTTGHPEGGSGMSHAGAAPETMAGPTAGSGPKNPFGPEHTAGWENTAAVASVAVPADASGTAAEGPHGPGGGASALGPAVPGTDADPGPGSASHDSGMAMDMSTLCVAILGAWVVLALVRAALGRRATWLTALRGALIAAVRPQPPPPGPLLAELSILRI
>NZ_CP016559.1|WP_003957673.1|6444017_6444701_-|HAD-family-phosphatase
MSIPRTTSVIFDLDGTLVDSEPNYWEAGRRLLAEYGVTDYDWERHSRFIGIGTRETLEILRGEYGIEASVETLLAGKNRHYLALARTATEVFPQMRAFVELLHAAGVPLAVASGSSRAAIEAVLAATGLDTLITTTVSAEEVPRGKPEPDVFLAAARLLGSAPADCVVVEDAAPGAAAAHAAGMRCIAVPYEEATAADPAFARADLLYAGGQSAFTAEGAYAWLRSR
>NZ_CP016559.1|WP_003957674.1|6445143_6446139_-|winged-helix-turn-helix-transcriptional-regulator
MLRIHFTGDDLRRVTVADGFDPLWEVLLSLHLAQEPDHGHLAFSEWRRTVRPLVREPSPLRLLTQLARPWGYSPDFLTPGRGEDGFGAQLDRVLSTPRARLKAELSQLAAESPPTPWTRALGSGDPGALRRLGDAMTAYHRRALAPYQGAMLAHAEADRAQQARALLSGGLDRLLSQLHPRVVWEAPVLQIPVYADQDVYLGGRGLVLVPSYFCRIQPITLMDGEQPPVLVYPISPPLGRLIRDPMRADADGTAPVVALLGRTRAALLEAAAHTGTTTELGRRVGVAPPVVSRHTAVLRKAGLLETRREGGAVRHRITRLGIALLNGEMPE
>NZ_CP016559.1|WP_003957675.1|6446257_6447391_-|pyridoxal-phosphate-dependent-aminotransferase
MTRLPDFRLETHLSRWEFTARHHLTASDMQTMTLSELLTLADDEDREAFGALSLGYTDTFGDPALREAVAGMYENAEADDVVCFAGAEEGLYLAMNVLLGADDHAVVVTPNYQSAETVPLALCEVTGVALDERHDWALDLDRVAAALRPNTRVVSVNFPHNPTGKVIPAADFAALTRMCDERGIRLFSDEVYRGLERDPARALPQAADLSERALSLNVTSKSLGMPGLRVGWIVCRDRELRSRLERAKHYTSICNAAPSEVLARIAIKARRSILERNRALIAEQLPLFDAFFADFPELFEWRAPDGGCVAFPRYRGADGVEEFCARLVAEAGVLLLPASVYRSELTATPDDRFRIGFGRRGAEEALREFGDWLRRRG
>NZ_CP016559.1|WP_003957676.1|6447387_6448056_-|hypothetical-protein
MRNESEHDTASGGSPDPRLTLWEPVCRAIALLLGPYAEVVLHDPDTDRVMGIWNAMGPRGAGDPSLLGELDALDPADRDVYGPYEKLLADGRRLSSVSAVLRAPDGHPSAVLCVNLDRTPLEQAAALLSSFGAPVVRRPEPLFEQDWSERIQHIVGGYVRDHGRPVERLGRAERLTVVGLLDEAGVFEVRRAAPVVAGALKASRSTVYALLSEHRARRTTTP
>NZ_CP016559.1|WP_003957677.1|6448247_6449276_-|hypothetical-protein
MRALRRATAAVTAAVAVLTGCSTGDGGGPAAEQPPARIRGITLPGWDTGDYERREAGRYLRQIAATGARWVVFTPTWYQDGTRRATPRAGQETVSDRGVRRVVGLARSAGLKVMLKPHVDLDDGGDRARIRPADRDAWFTAYRGFITHYARIAAELGVEQFAVGTELAGTSADRANWRRVIRVVREVYPGPLTYAANYDEYDRIGFWSSLDLIGIDAYWPLADAATADPARLARGWEPVVGELAAFAARQHRRILFTEAGYTSQHGAVTAPYSWTVSGRPGYAEQAAAYEALLTAFDGRPWWAGVCWWMWDDWPDSAETPQRLAYSPRGKPAEEVLRRRWKE
>NZ_CP016559.1|WP_003959441.1|6449493_6451374_-|DUF2334-domain-containing-protein
MSQPRRRTRPAWSAFIALGVAALLGGGLLTPGTAAARDGLGGVGGSANLAHTSGIQGQNTKAIASAALKADAERRAQKATQRGVRSPGVQQTVKKLEKLRSEAAPRPRAKAQAAPPGQAKALVLYDNAGPFGHLGELYAMGMANLGGRFGTVTSKPVQEYTSGMIETFDTTVYIGSTYYNASLPDAVPQDFYLDVLLSDRPVIWMGQNIWNMAHSISLQEFEFKYGWDPTNSYYDNGAGIGRVSKVEYKGQTLTRRIPDGQDPGILRPLIKQGPGYPDPTVVATAVDTDGGVEKRFPWALRSGNLTYIGELPFTFVSEADRVVAIHDLLFDALAPQTAEQHRALIRIEDINPLSDTTRLRAIADYLKSQNIAYGINVIPVYSDPKGSENNGIPRTVRLQQRPALVNTIKYMLANGAVLMNHGYTHQYGNVDNPYNGVTGADFEFFRAHVNPANNHVVYDGPVAEDSTAWAQGRVDAGLNEFTRAGLPRAKLWTTPHYAGSATDYRVFSQNYAARLERSLYFAGTLTGQPVDSTRYLGQFFPYPVTDVYGTKVLPENIGSYEPVASNQNPPRLEADLIANAKANLAVRDGFASFYYHPFHTVAPLKTIVEGIQALGYTFVSPESLLS
>NZ_CP016559.1|WP_003959440.1|6452005_6453247_+|glycosyltransferase-family-2-protein
MNADPLIWASILLIVLAGTYNFGLFLLSRRKVPLAPPSGEQRFYVFLLACLNEEMVLGDSLARITELPAENCVALVIDDASDDRTAEIARAADPDRVWLHQRHLPDARRGKGAALNDGVRLLRASGLLGGRDPQDVIICVVDADGRLDRHVIEAVDPFFNDPSTGATQIGVRMYNREKGLLARLQDMEFVVYGDVFQSARRFIGSVGMGGNGQFMRLSALDSLGENPWSDSLTEDLDLGVRLIAKGWTNQYCPTAAVSQQAVLDVRRLVRQRSRWFQGHLQSADLAPLILRDVPGRAAMDLIYHLSSPVLILLTSLLPLSFLVAVLGTVAGSVARGEPMVDVMWFAGPYVLSFTVAWIYGFVYRQRERTLRPLQAALLGHAFVFYGYIWFAAGWMGVWRTVTGKTTWLKTARS

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP016559_18	18.1|5720247|26|NZ_CP016559|CRISPRCasFinder	5720247-5720272	26	NZ_CP016559.1	4920924-4920949	1	0.962
NZ_CP016559_19	19.1|6441404|30|NZ_CP016559|CRISPRCasFinder	6441404-6441433	30	NZ_CP016559.1	5915183-5915212	1	0.967

1. spacer 18.1|5720247|26|NZ_CP016559|CRISPRCasFinder matches to position: 4920924-4920949, mismatch: 1, identity: 0.962

cagagcgtgcgccgacggacgccccc	CRISPR spacer
cagagcgtgcgccgacggtcgccccc	Protospacer
****************** *******

2. spacer 19.1|6441404|30|NZ_CP016559|CRISPRCasFinder matches to position: 5915183-5915212, mismatch: 1, identity: 0.967

ggggcgtccgtcggcagacgcttcagcgtc	CRISPR spacer
ggggcgtccgtcggcggacgcttcagcgtc	Protospacer
***************.**************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MN694304	Marine virus AFVG_250M1043, complete genome	35213-35236	2	0.917
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	686540-686563	3	0.875
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	98957-98980	3	0.875
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	629633-629656	3	0.875
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	KU985096	Mycobacterium phage Kazan, complete genome	43181-43204	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MG099952	Mycobacterium phage WunderPhul, complete genome	42977-43000	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MK359352	Mycobacterium phage JewelBug, complete genome	43913-43936	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	KX375815	Mycobacterium phage ToneTone, complete genome	42908-42931	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MK494090	Mycobacterium phage Jordennis, complete genome	43407-43430	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	KX641261	Mycobacterium phage Isiphiwo, complete genome	43192-43215	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	KF560333	Mycobacterium phage Artemis2UCLA, complete genome	42885-42908	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	KU695582	Mycobacterium phage McFly, complete genome	43810-43833	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MT024861	Mycobacterium phage Pmask, complete genome	43814-43837	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MK359360	Mycobacterium phage Hexamo, complete genome	42882-42905	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	KX576638	Mycobacterium phage Gruunaga, complete genome	43206-43229	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MH051253	Mycobacterium phage GreedyLawyer, complete genome	43141-43164	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NC_042309	Mycobacterium virus Gladiator, complete genome	43251-43274	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MT657338	Mycobacterium phage SuperCallie99, complete genome	43697-43720	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NC_042334	Mycobacterium virus Jeffabunny, complete genome	42975-42998	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MN728683	Mycobacterium phage Yokurt, complete genome	42979-43002	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NC_022965	Mycobacterium phage CloudWang3, complete genome	43397-43420	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	JF937092	Mycobacterium phage DaVinci, complete genome	42576-42599	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	JN698999	Mycobacterium phage Blue7, complete genome	43105-43128	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MF668288	Mycobacterium phage Wiks, complete genome	42979-43002	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MH020240	Mycobacterium phage SuperAwesome, complete genome	43853-43876	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NC_042318	Mycobacterium virus Hammer, complete genome	42913-42936	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MG099945	Mycobacterium phage Koko, complete genome	43737-43760	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MK894433	Mycobacterium phage Kipper29, complete genome	43194-43217	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NC_022985	Mycobacterium phage Zaka, complete genome	42979-43002	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	JN049605	Mycobacterium virus EricB, complete genome	43168-43191	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	MH779517	Mycobacterium phage Zulu, complete genome	43357-43380	4	0.833
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NC_029077	Mycobacterium phage VohminGhazi, complete genome	43176-43199	4	0.833
NZ_CP016559_10	10.1|3003067|25|NZ_CP016559|CRISPRCasFinder	3003067-3003091	25	MT270409	Phaeobacter phage MD18, complete genome	71939-71963	4	0.84
NZ_CP016559_10	10.1|3003067|25|NZ_CP016559|CRISPRCasFinder	3003067-3003091	25	MN602268	Bacteriophage DSS3_MAL1, complete genome	109132-109156	4	0.84
NZ_CP016559_3	3.3|1234225|24|NZ_CP016559|CRT	1234225-1234248	24	NZ_CP022417	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-2, complete sequence	154461-154484	5	0.792
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NZ_CP034999	Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence	299564-299597	5	0.853
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NZ_KY000068	Agrobacterium deltaense strain Tun151 plasmid pTi_Tun151, complete sequence	96789-96818	6	0.8
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NC_007491	Rhodococcus erythropolis PR4 plasmid pREL1, complete sequence	28546-28575	7	0.767
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NC_015952	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence	56858-56887	7	0.767
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NZ_CP050125	Rhodococcus erythropolis strain KB1 plasmid plas1, complete sequence	210086-210115	7	0.767
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NZ_CP034156	Rhodococcus sp. NJ-530 plasmid unnamed4, complete sequence	216900-216929	7	0.767
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NZ_CP008954	Amycolatopsis japonica strain DSM 44213 plasmid pAmyja1, complete sequence	20364-20397	7	0.794
NZ_CP016559_19	19.1|6441404|30|NZ_CP016559|CRISPRCasFinder	6441404-6441433	30	NZ_CP039899	Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence	202628-202657	7	0.767
NZ_CP016559_19	19.1|6441404|30|NZ_CP016559|CRISPRCasFinder	6441404-6441433	30	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	653816-653845	7	0.767
NZ_CP016559_19	19.1|6441404|30|NZ_CP016559|CRISPRCasFinder	6441404-6441433	30	NZ_CP039890	Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence	202628-202657	7	0.767
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NC_012520	Rhodococcus opacus B4 plasmid pROB01, complete sequence	28222-28251	8	0.733
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NZ_CP021375	Rhizobium sp. ACO-34A plasmid pRACO34Aa, complete sequence	98215-98244	8	0.733
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NC_023316	Streptomyces sp. 14R-10 plasmid pZL1, complete sequence	99732-99761	8	0.733
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1854786-1854815	8	0.733
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	167716-167749	8	0.765
NZ_CP016559_14	14.1|4682620|40|NZ_CP016559|CRISPRCasFinder,CRT	4682620-4682659	40	NC_004934	Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence	25492-25531	8	0.8
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	717594-717623	9	0.7
NZ_CP016559_3	3.2|1234177|30|NZ_CP016559|CRT	1234177-1234206	30	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	330956-330985	9	0.7
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NC_023722	Rhodococcus phage ReqiPine5, complete genome	42269-42302	9	0.735
NZ_CP016559_15	15.7|4692332|37|NZ_CP016559|CRISPRCasFinder	4692332-4692368	37	MK880124	Microbacterium phage IAmGroot, complete genome	6862-6898	9	0.757
NZ_CP016559_15	15.7|4692332|37|NZ_CP016559|CRISPRCasFinder	4692332-4692368	37	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	352156-352192	9	0.757
NZ_CP016559_15	15.7|4692332|37|NZ_CP016559|CRISPRCasFinder	4692332-4692368	37	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	472590-472626	9	0.757
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NZ_CP033971	Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence	23780-23813	10	0.706
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NZ_CP007792	Corynebacterium marinum DSM 44953 plasmid pCmarinum1, complete sequence	80406-80439	10	0.706
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	504747-504780	10	0.706
NZ_CP016559_15	15.7|4692332|37|NZ_CP016559|CRISPRCasFinder	4692332-4692368	37	NZ_CP040824	Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence	69161-69197	10	0.73
NZ_CP016559_15	15.7|4692332|37|NZ_CP016559|CRISPRCasFinder	4692332-4692368	37	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	626227-626263	10	0.73
NZ_CP016559_15	15.7|4692332|37|NZ_CP016559|CRISPRCasFinder	4692332-4692368	37	KT001914	Caulobacter phage Seuss, complete genome	75763-75799	10	0.73
NZ_CP016559_9	9.1|2805970|34|NZ_CP016559|CRISPRCasFinder	2805970-2806003	34	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	14401-14434	11	0.676

1. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MN694304 (Marine virus AFVG_250M1043, complete genome) position: , mismatch: 2, identity: 0.917

ccgttgatccggctgacgctccgg	CRISPR spacer
ctggtgatccggctgacgctccgg	Protospacer
*.* ********************

2. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgatccggctgacgctccgg	CRISPR spacer
tcgttgatccgggtgacgatccgg	Protospacer
.*********** ***** *****

3. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgatccggctgacgctccgg	CRISPR spacer
ccgttgatccggctgacgatcagc	Protospacer
****************** ** * 

4. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgatccggctgacgctccgg	CRISPR spacer
ccgttgatccggctgacgatcagc	Protospacer
****************** ** * 

5. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to KU985096 (Mycobacterium phage Kazan, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

6. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MG099952 (Mycobacterium phage WunderPhul, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

7. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MK359352 (Mycobacterium phage JewelBug, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

8. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to KX375815 (Mycobacterium phage ToneTone, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

9. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MK494090 (Mycobacterium phage Jordennis, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

10. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to KX641261 (Mycobacterium phage Isiphiwo, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

11. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to KF560333 (Mycobacterium phage Artemis2UCLA, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

12. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to KU695582 (Mycobacterium phage McFly, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

13. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MT024861 (Mycobacterium phage Pmask, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

14. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MK359360 (Mycobacterium phage Hexamo, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

15. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to KX576638 (Mycobacterium phage Gruunaga, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

16. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MH051253 (Mycobacterium phage GreedyLawyer, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

17. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NC_042309 (Mycobacterium virus Gladiator, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

18. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MT657338 (Mycobacterium phage SuperCallie99, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

19. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NC_042334 (Mycobacterium virus Jeffabunny, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

20. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MN728683 (Mycobacterium phage Yokurt, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

21. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NC_022965 (Mycobacterium phage CloudWang3, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

22. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to JF937092 (Mycobacterium phage DaVinci, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

23. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to JN698999 (Mycobacterium phage Blue7, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

24. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MF668288 (Mycobacterium phage Wiks, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

25. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MH020240 (Mycobacterium phage SuperAwesome, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

26. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NC_042318 (Mycobacterium virus Hammer, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

27. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MG099945 (Mycobacterium phage Koko, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

28. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MK894433 (Mycobacterium phage Kipper29, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

29. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NC_022985 (Mycobacterium phage Zaka, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

30. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to JN049605 (Mycobacterium virus EricB, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

31. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to MH779517 (Mycobacterium phage Zulu, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccga	Protospacer
. *******.*************.

32. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NC_029077 (Mycobacterium phage VohminGhazi, complete genome) position: , mismatch: 4, identity: 0.833

ccgttgatccggctgacgctccgg	CRISPR spacer
tggttgatctggctgacgctccgc	Protospacer
. *******.************* 

33. spacer 10.1|3003067|25|NZ_CP016559|CRISPRCasFinder matches to MT270409 (Phaeobacter phage MD18, complete genome) position: , mismatch: 4, identity: 0.84

ccccgtcaaaccgccccggcggctc	CRISPR spacer
ccccgtcgaaccgccccggcgagtt	Protospacer
*******.*************. *.

34. spacer 10.1|3003067|25|NZ_CP016559|CRISPRCasFinder matches to MN602268 (Bacteriophage DSS3_MAL1, complete genome) position: , mismatch: 4, identity: 0.84

ccccgtcaaaccgccccggcggctc	CRISPR spacer
ccccgtcgaaccgccccggcgagtt	Protospacer
*******.*************. *.

35. spacer 3.3|1234225|24|NZ_CP016559|CRT matches to NZ_CP022417 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-2, complete sequence) position: , mismatch: 5, identity: 0.792

ccgttgatccggctgacgctccgg	CRISPR spacer
ggattgatccggctgacgctcccc	Protospacer
  .*******************  

36. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NZ_CP034999 (Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence) position: , mismatch: 5, identity: 0.853

-gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
ggtgcggc-cgacgtcggtcgccgcgtccttgacc	Protospacer
 ** **** ******* * *************** 

37. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NZ_KY000068 (Agrobacterium deltaense strain Tun151 plasmid pTi_Tun151, complete sequence) position: , mismatch: 6, identity: 0.8

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
ggcatgatccggccgaggttccagctccgg	Protospacer
    ************ ***** *******

38. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NC_007491 (Rhodococcus erythropolis PR4 plasmid pREL1, complete sequence) position: , mismatch: 7, identity: 0.767

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
gttttgatgcggccgacgtttccgctgccg	Protospacer
 . ***** ***********.***** * *

39. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NC_015952 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence) position: , mismatch: 7, identity: 0.767

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
cgcccgttccggccgaggtgcccgctccgg	Protospacer
*  ..* ********* ** **********

40. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NZ_CP050125 (Rhodococcus erythropolis strain KB1 plasmid plas1, complete sequence) position: , mismatch: 7, identity: 0.767

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
gttttgatgcggccgacgtttccgctgccg	Protospacer
 . ***** ***********.***** * *

41. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NZ_CP034156 (Rhodococcus sp. NJ-530 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
gttttgatgcggccgacgtttccgctgccg	Protospacer
 . ***** ***********.***** * *

42. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NZ_CP008954 (Amycolatopsis japonica strain DSM 44213 plasmid pAmyja1, complete sequence) position: , mismatch: 7, identity: 0.794

gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
ctccggctcgacgtccggcgtcgcggcggcggcg	Protospacer
 *******************.**** *  .*.**

43. spacer 19.1|6441404|30|NZ_CP016559|CRISPRCasFinder matches to NZ_CP039899 (Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence) position: , mismatch: 7, identity: 0.767

ggggcgtccgtcggcagacgcttca-gcgtc	CRISPR spacer
accctgtgcgtcggcagacgcttcaggcgt-	Protospacer
.   .** ***************** **** 

44. spacer 19.1|6441404|30|NZ_CP016559|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.767

ggggcgtccgtcggcagacgcttcagcgtc	CRISPR spacer
ggcgcgtccggcggcagacgctttgccgcg	Protospacer
** ******* ************.. **. 

45. spacer 19.1|6441404|30|NZ_CP016559|CRISPRCasFinder matches to NZ_CP039890 (Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence) position: , mismatch: 7, identity: 0.767

ggggcgtccgtcggcagacgcttca-gcgtc	CRISPR spacer
accctgtgcgtcggcagacgcttcaggcgt-	Protospacer
.   .** ***************** **** 

46. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NC_012520 (Rhodococcus opacus B4 plasmid pROB01, complete sequence) position: , mismatch: 8, identity: 0.733

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
gtcttgatacggccgacgtttccgctgcca	Protospacer
 . ***** ***********.***** * .

47. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NZ_CP021375 (Rhizobium sp. ACO-34A plasmid pRACO34Aa, complete sequence) position: , mismatch: 8, identity: 0.733

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
acatcataccggccgacgttccagctccgt	Protospacer
 *.*..  ************** ****** 

48. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NC_023316 (Streptomyces sp. 14R-10 plasmid pZL1, complete sequence) position: , mismatch: 8, identity: 0.733

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
atgcccaggcggccgacgctcccgctccgg	Protospacer
 .*.. *  *********.***********

49. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 8, identity: 0.733

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
gcaatgatccggccgacggtcccggtcgaa	Protospacer
 *. ************** ***** ** ..

50. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 8, identity: 0.765

gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
gaacggcgcgacgtccggcgcggcgtccccgggg	Protospacer
*  **** ************* ******..*. *

51. spacer 14.1|4682620|40|NZ_CP016559|CRISPRCasFinder,CRT matches to NC_004934 (Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence) position: , mismatch: 8, identity: 0.8

-gcgcgcactggctcggccagcccctggccgtcgtcggcga	CRISPR spacer
gccgtgc-ctacctcggtcagcccctggccgtcgtcgtcgt	Protospacer
  **.** **. *****.******************* ** 

52. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 9, identity: 0.7

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
ggggcgatccggccgacgttcctgctggtc	Protospacer
  * .*****************.***    

53. spacer 3.2|1234177|30|NZ_CP016559|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 9, identity: 0.7

ccgttgatccggccgacgttcccgctccgg	CRISPR spacer
ggggcgatccggccgacgttcctgctggtc	Protospacer
  * .*****************.***    

54. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NC_023722 (Rhodococcus phage ReqiPine5, complete genome) position: , mismatch: 9, identity: 0.735

gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
gatcgcctcgacgtccggcgccgcatcccgcgag	Protospacer
* .** ******************.***.  . *

55. spacer 15.7|4692332|37|NZ_CP016559|CRISPRCasFinder matches to MK880124 (Microbacterium phage IAmGroot, complete genome) position: , mismatch: 9, identity: 0.757

gccccgacgccatggtcgccgccgtccgcatggtcat-	CRISPR spacer
acctcgacgccatcgtcgccgccgtccg-ataaccccc	Protospacer
.**.********* ************** **...* . 

56. spacer 15.7|4692332|37|NZ_CP016559|CRISPRCasFinder matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 9, identity: 0.757

gccccgacgccatggtcgccgccgtccgcatggtcat	CRISPR spacer
ccgccgtcgccatggccgccgccgtccgccgggcgct	Protospacer
 * *** ********.*************  **.  *

57. spacer 15.7|4692332|37|NZ_CP016559|CRISPRCasFinder matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 9, identity: 0.757

gccccgacgccatggtcgccgccgtccgcatggtcat	CRISPR spacer
ccgccgtcgccatggccgccgccgtccgccgggcgct	Protospacer
 * *** ********.*************  **.  *

58. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NZ_CP033971 (Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
cacacactggaagtccggcgccgcgtccttgcga	Protospacer
  *  .** ** *******************  .

59. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NZ_CP007792 (Corynebacterium marinum DSM 44953 plasmid pCmarinum1, complete sequence) position: , mismatch: 10, identity: 0.706

gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
aaccggctcgacgtcctgcaccgcgtgtgtgtga	Protospacer
. ************** **.****** . **  .

60. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.706

gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
cgtcggctcgccgcccggcgccgcgtcggtcggg	Protospacer
  .******* **.*************  * . *

61. spacer 15.7|4692332|37|NZ_CP016559|CRISPRCasFinder matches to NZ_CP040824 (Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence) position: , mismatch: 10, identity: 0.73

gccccgacgccatggtcgccgccgtccgcatggtcat	CRISPR spacer
agcccgacgccacggtcgcggccgtccgggccttcct	Protospacer
. **********.****** ******** ..  ** *

62. spacer 15.7|4692332|37|NZ_CP016559|CRISPRCasFinder matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 10, identity: 0.73

gccccgacgccatggtcgccgccgtccgcatggtcat	CRISPR spacer
aggccgacgccatcgtcgcggccgtccgctcgcagat	Protospacer
.  ********** ***** ********* .*   **

63. spacer 15.7|4692332|37|NZ_CP016559|CRISPRCasFinder matches to KT001914 (Caulobacter phage Seuss, complete genome) position: , mismatch: 10, identity: 0.73

gccccgacgccatggtcgccgccgtccgca--tggtcat	CRISPR spacer
tcgccgacgccctggccgccgccgtccgcgcccagcc--	Protospacer
 * ******** ***.*************.  ..*.*  

64. spacer 9.1|2805970|34|NZ_CP016559|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 11, identity: 0.676

gtccggctcgacgtccggcgccgcgtccttgacg	CRISPR spacer
cagcggctcgaggtccggggccgcgtcgccgcac	Protospacer
   ******** ****** ******** ..*   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	6772467 : 6787533	12	Synechococcus_phage(25.0%)	plate,tail	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP016559|6772467:6787533|DBSCAN-SWA
CTCATGACAACTGCGTATGCACACCGACGGCCGCCGCCACGCCCACGCCCACACCGCGCCGCGCGCCCCGTGGCCCGGGCCGCAGCACCCCGTCGCGGTTGAGCCGCAGCGGACGCGCGCCCCCGAGCACCGGCGGCGGCAGCGGGACGAACGCCGTGTCCACGCCGACCGTGGAGCGCGAACCGACCACGAGCCCCGAGCCGCCGGCGCGCACCGAACCGACCGTGTGCGCGGGCGCCTGCCGCCGCACCAGCCGGGCCAGCGCCGCCCCGTCTGCCGCCCCCGCGGGCAGCAGCAGCCGGAACCGGTGCGCCTGCGCGGTGAGCGGATCGGCGTCCGGGTCGCCGAAGGCGCGCAGCGGCGCCGCGCCCAGGGCCGAGCCGCCCACCCGGAACCGTCCGGCGGCCCGGCCGAACAGCCGTACCGTGCCCAGCCCCTCACCGGCACCGGCCGCCCCCGCCGCCGCGCCCGGGGGGCGGAGCTGCGCCCAGCGCCGGTCGGCCGCCAGCTCGTCGATCACCGGCGCCACCCCGAACACGATGCGCACCGCCTCCCGCAGCGCCCAGGGCGTGCCCCGGCGCCGGTACAGCTCCGGCGCCGCGGCCAGCAGGGCACGCCGGGTCGCCGCGTCCCAGCCGGACTCGTACGAAAGACCCAGCAGCCCGGCCAGCCAGGGCAGCGCCCGGTCCGGGACACCGGCGGGGTCCAGCAGCGCGGGAGCGCGTTCGATGGTCCGGTCCAGTTCCGCGAGGGTCGCGTCGAACAGCGACAGGAACCGCTCGGTGAAGTCGTCCGCCGCCGGGTCCTCCCGGAACGCGGGCGGCAGCAGATCCGCGCCGGTCACCCGGGGGAAGTCCAGCCGGACCCGGCGGACCACCGGGGTGGCGGAGCCGTCGCCCGTGAGCCGCAGCCGCAGCCGCAGGAAGCGGCCCGGCGGCTGGTCGACGAGGAAGTCGGTGAGGCCCGGGGCCGCGTGCTGCCAGTCGGAGTCCGCGCAGCCGCCGTCCTCGGTCACCACGATCGAGGCGGTGACCGCCGTGCCCGGCGGGAGGTCGGCGTCCAGACGGACGCGGTGCCAGCGGCAGCGGGCGATGCCGCTGTCGATCAGCGCCGTCAGCAGATGGCCCGAGGTCACGAGGTCGGCGGTCGGCGCCGGCGGGGTGGTCCGCGGCCCGCCGTGCCAGGTCCAGCAGGAGGTCACGGGCTCCTCGGGGCCCGGTTCCCGCAGACAGAAGCCGTCGGCGTCGGCCGCGGCCAGGGTGCTCGGAGGCAGGGCGGCGGCCAGTTCGGCCGCGGTCGCGGGCCGGAAGGGCCGCCCCCGGCCGCCCCGGTGGACGCGCGGCACACCGCCGTCCTCGGTCAGCAGCCAGATCGTGCCGTCGGGCGCGGCGCGCAGCCCGGCCACCGCTCCGGCGGCCCCGGTCCGCAGCACCTCGCGCAGCCGTCCGTCCGGGCCGTAGCGGCGCAGCGCGGTGGTGCCGCGGCGGGCCACCAGGATCTCGCCGCGGGGCGCGGGCGCGGCCCAGCGGGCCCCGTCGACGTCGATGACGGCGGTGAGCCGTCCGCCCTCGCGGTCCCACACGAGCACCCGGCCGGGCTCGACCACGACCAGCCGGTGGCTCCGCGCGGCGACGGACCACGGCCGCACCAGGGGCACCGGGCCGCACGCCGGCGGCCACACGGGCAGCCATCCGCCGCCGCACACGTCCCGCCGCAGCAGCCCCGGCCGCTTCCCGGGCACCAGCAGATACCAGTCCCCGGCCCGGCACCCCGGCGCCAGCCGCCGATCGGGGAACCAGGGCAACAGCTCCCCCCGGGTCGGCCCGTCCGGCACCCCCCGACGGGCCAGCCGGATGCCCTCGGGATCGTCGAGCCCGACGATCCCCGAAACCCCCGGCTCCTCCGGACCGGTGTACGGGTCCCACCCGGTCCACGCGTCGAGCAGCCGGAACGTCGCCGGCCCCGGAACACAGCTCATGAGCCCTCTCCTCCCGCCGCCCCCTCGACCGCCCCCACCCGCACCGGCGCCCCGCCGCGCCCACGACCGTCCGCGAACGGCCGCCCCGAGCCGGGACACCTGCCTCCGCGCCGGGAACGGCCGGAGCCCGACCCGCCGCCGGTACCGAACGCGGCCCCGGCGCGGTGGTGTGCCCGTGCCGGGAACGACCGCGGCCCGCTGTTGCCGTGCGTACGGCTGCGGCCGGCGCCGCCGTGCCGTGCGCCGGTGGTTCCCGGGCACGGCGGGGTGGTGGCGCGGTGGCGCCGTGGCCGCCGTGCGGGCGGCTGGGGCGCGCTGCCCGGTGTGCGCCGGAGGCCGTGGCCCGCACCGGTGGTGGCGCGGTGGCGCCGTGCCGGGGAGCCGGTGCGGCGGGTCGGAGCCGTCCCGCCGGGCACGGGGGAGGGCCCGCCGTCGGCGTCCGTACGGCCGTATCCGCCCCAGGGCCGGGGCCCGCGCTGTCCGCCGGTGGTGATGTGGGCCCGCGGCGCACGGACCCCGGAACGGGGCGTTCCCGCCGTCGGGCACCTGCCGTCGTGTCCGGGGCCGGGCCGGGGCCCGGAGACCCGTGCGGACGCGGCGCGGTGCCGCGGTGGGGCGGGGACGCGGTGGTGCCGTGGCTGTGCCCGCTGCGCACGGCCGCGGTCGTGGCCGCCGTCGGCCGCCGACGCCCGGACGGGCACGGGGTGTTCCTGCGCCGGGACCGGCCGCGGCCCGCTGCCGCGCCGGGCCCCCGCGGTGCCGTCCGGCGGAAGGACGGGTGCCGTGGCGCGTGGTGTCTGCGGACGCACGGCGGAGGACGGGGGTACGCCCTCCCGTCCCCCGGGCCGCCGGGGCGCGGGGGAGTGCCTGCGAGCCGTCGCGACGCGGGCGGGACCCCGGTGGCACGACGGGAGGCCGTGGCCCGCACGGGTGACGGTGCCGTGCCGCCGTGCCGGGAACGCCCGTGGCCCGCCGTCGCCGTGCACGTGGCTGCGGCTGTCACCGGGTGCGGGCGTGGTGCGGTGGGGTGCGCCGAGGGCCGCAGGGCTCGGCGGATCGCCGTTGACGCGGTGGTGCCGAGAACGGGGCGTCCCCGCCCTCGGGCACCTGCCGTCGGGCACGGGTCGCGGTCGCGGCGTCGGGACGGGTGCGGAAGGCAGGGAAGGCAGGGTCATGACGGGGCTCCCGTGTCCTCGACCGGGATCAGCAGGGGGCGTTCGGGCCACACCAGGCGGTCCGCGCCGATGGGGTGGTCGGCGCACGCGGGCAGCCGTACCCCGTCGACGGTGAAGGAGAGCCGGGACACCGACAGCACCCCGTCGACCGTCAGCAGCCGCCGCACCAGCGGCGTGTGCCGCAGCGCGCCGCCGAACGGCCAGCCCGCGCCGTCGTCGCCGCCGCGCAGCGGGTCCAGATATCCGGTCACCGCGTCACCCGCCCGCGCCAGCACCGCCGAGCGGTCCTGGTCCGGGTCGAGGGTCACCCACGCCTCCACGGCGACCCTCCGGTACGCCACGGGGGCGGCGACCACCGTCACCCCTGCGGGCGCCACCGTGCCGGTGAGGAAGTCGGCCACCGCCTGGAGCGCGGCGGCGGTGGGCAGCGGCGGGCCCGCCGCCGGGTCCGCGTCCGGCAGGGGCTCCGGCACCACGAGCACCCCCACCACACCGGGGATCGCGACCCCCGGGTAGCCGGGGTGCAGACCGGGCACACCCCGGGCGCGGGCCACCGCCGCTCCGGGCGCGCGGGTCGCCAGCAGCCCGTAGTCGGCGGGGGCCACGGCCCGCCCCCGGGCGCGCAGTTCGCCCACGCCCCGGCGGATCGCCTCCGCGTCCGGCTCGGCGTCCTCGCCCCCCGACGCCGGGAACGGATTGGTCACCCCGAGCACGAACGGCAGCGCGGTCACCACCGCGTTGACGGCTCCCGCGGCGACCGTGCCCGCCGCGCCGCCGCCCACGCGGTACCGCACCGCGCGCACATTGCGGAACCCCGGCGGCACGGCCGCGCCGTGCACCCCGTCCCCGAAGGCCACCTCGCCGGTGGCGTGGTCCACGGTGAACACCCGGTCGTCCGCGCCGTACGCGGCCAGGCTCTCCACCTCCTGCCAGCGGGCGGCGGTCGGCACGGTGGTCCCGAAGACATCGCCGCCCGTGTCGTCGTCGACCTCGATCACCAGCGACCCGGCGAGGATCGGCACCTGGCTCAGCCGCAGCACCCGGCGGCCCGCGCCGGAGACGTCCTGCACCGGTTGCAGCGGCTCGTCGCGGACCGTGCGGGCGGCGGTCGCCGCGACCGTGTTCAGCCGCAGCCCCGACACCACCGGGCCGGGCCCGTCGAAGGCGCCGTGCGCGATCCGCAGCCGCAGCCAGCGCAGCGGCGGCCCCTGCCGGAACCCCGCAGGAGTGCCCGGCGCCCACGTCCGGGGCACCCGCAGCTCCACGGTGCCGCTCCCGCGCAGCCCGTCCGTGCCGTCCCGGACCACCTCGGCGGGGACGAACCGGGTCCCGTCCAGGACGTCCCACTCCAGCAGCGGCCCGGCGGGCGGCGGGAGTTCCGCGCCACCGGAGCGCGCGGGCGCGGGCGGCACCGCGACCACCACGAGCCCCAGCGACAGCCGGGGGTACGGGGCCGCCGCCCCGGCCAGCGCGATCCACAGCCCGTCGCCCGGCCGGGGGTCCCGGCCGAACGGCGCGAACGGCCGCCCCGGCCCGGCGGGCCCCAGCGGCAACTGCTCCGGCGTCCCCGCCTCCTGCACCGCGAGTGCCGCCACCGTCGCCGGGGTCGCGTACAGGTCGTCGTCCGTCTCGTAGACCACCTGGCCGTCCGGTCCCGGCGCGGCGGCCTGGAACCCGGCCGGGACGAGCACCGACGCCCCGTCCGGCGGGTTCACCGTGAACTCCAGCAGCGCGGCGGCCGGCCCGGCGGGCCTGCGCCGCACCCCGGCCGTGGCCAGGTGCTCCGCGAGGATCTTCTCCGGCAGCCGGTTGACCCGGCTCAGCACCGGCTCGGCCTGGGTGCCGAACAGCCGCACCAGCGCGACCCCCGCGTCCTGGCGGTCCGACGCGGTCCAGTCGGGGGTGTATCCGGCGATCCGGCCGCGCACCGCGCCGCGGACGGCCTCCCGGGTCGCGTCCACCAGCTCCGGCTGCACACCGCTCGGGCCCGGGCCCGGCACCATCCGGCCCTCCGCGCGCGCCCCGCGCTCCCACCACACACCGTCGGTCATTCCAGCCCCTCCCCGCCGCCCGACGCGGCGCTCACCCGGGTCCGGACCGACCGCAGCACCGGCAGCTCCGCCGCCCGCAGCCGCACGTCCCGGCAGTCCTCCCCGGGCGCGGCGCCGTCGAGACCGATCGCGACACCGGCGACCTCGGCCAGGTCGCCCAGCGCCCGCTGCGCGGCCCGCAGCAGCGCCGCGGGCCGCAGCGGCCCGCCGAACGGCCACCCCCCGGCGTCCTCGCCGCCCACCAGCGGATCGAGATGGCGGCGCAGCGCCGCCGTGAGAACCGCCGCCACCCGCGCCCGGTCGGCGGGGGCGCCCGCCAGATCCACCCGCAGCGCCACCTCGCGGTAGTCGGGCGGGCGGACGAACACCTCCGAGGTGAGCAGCCGCGCCCCGGCGAGCCGCCGGGCCACCGCGCACAGCGCGCCCGGGTCCGGCACGGGCGCGGCGACCTGCCCCGCCGGGTCGTCGTCCCGGGGCACCCCCGGCACGATCCGCACGGTCACCGCGCCCGGCACCGCGGCGCAGGGGAAACCGGGGTGTTCCCCGACCGAGGCGTGGGCGCGGGCCACGGCGACCCCCGGGGTCGTGCGCGCGAGGGTGACGAAGTCCTCGGCGGTGACCGCCCGGGTCACCTCGCCGAGCGAGCCGCCCGCGCGGTCGCGGGCCCCGGCGACCGTCTCCGGGTCCGCGCCGCCCGCCGCCTGCACCGGGTTGGCGCCGCTCAGCGCGCCCCGCCGGGCGATCGGGCCGTCGGCGGGCAGCCAGTTGTCCGTCAGCCCGCCGTTGCCCTCCCGGCCGCCCCCGAGCCCGTACACGACGTGGACCTCGTCCCCGGGCCGGGGGACGGCGCCGGTGAGCCCGTCGCCGAAGACGAGCGCCCCGGCGGCCCGGTCGAGGGTGAAGACCCGGTCGCCGGGCGCGCCGAAGGTGAAGTCCGGGACGGGCCGCCACTCCTGACCGGCGATCACCGCCGCCGCGTCCAGGAGCCGCCCCCCGGCGTCCGGGAGCACCAGCCGCTGACCGGGCAGTTTCAGCCATGCCTCGGTCTGCTCCGCCACCTCCCGAGCGGTGGCGGTCCGCCGCCGGCGGTTGCGCGCGGCGGACACGTTGACGTCGAGCCGCAGCAGCCGGGGCGGCGCGGCGAAGGTCGCCGCGTCGGCGGTGAGCAGGACGCCGCGGTCGAGGGTGGTCCAGTCGGCCGGGGGGTGGAGCCGCACCACCCCCGGCCGCCGCAGCCCGGCCGTGCCGTCGTCGACCCGTGCGAAGGCGCCCGCCCGGTCCGTGCCCGGCCGGAACCAGGACCAGGTCAGCTCCGCGGGCGGCGGGACGTCCCCGACCGCCCCCGGCAGCCAGGACGGCACGCACGCCGCCGGGGCGTCCAGGCCGAACAGCAGGGACAGCGGCCCCGGCGCCGGATGCGCCCCGGCCAGCGGCAGGGTGAGGGCGACCCGGGCCGGGCCGCCGTCGGCCGCGAGCAGCGCCACCGGCCGCCCGGTCCGCAGATCCGCCGTCCGGTCGCGGTCGGTGACGACGGTGATCCCGGCCGAGGGGTCGAGCGGATAGACGGCCACGTCGTCGTCGAGACAGAAGGGGATCAGCCCCCGCGGGTCCCGGGACAGCGCGGTCCCCGCGGGGACGACGGGCACCGCCGTGTCCGGCCACTCGGCGGTCAGCCGCAGCACGGTGGCCGCCGGGACGGCGGGCCGCGGCGGATCGCTGCCCAGCAGCCGCAGTATGGCCACCACCAGCGCGTCCGGCACCTGGTCCAGCCAGTACAGCCGCTGCTCCAGCAGATAGGCGAAGAGCTCCAGCAGGGTGACCCCGGGGTCCACGGGCGCGTGCAGCGTCCAGCGCCCGTCGGACTCGGCGGGGATGCGGCGGCGCACCGCCGCCATCATGTCGGCCCAGGTGAGATCGTCCAGCCGGGGCGGGGGCAGGGTCATGGTGTACTCCCCAGCAGACCCGTGTAGTACGGGAAGACCAGATTGGCCTTGGTGTTGCTGCGCCGGACGCGGTACTCGACCGAGACGGTCACCCGGGACCCGTCGACGGGGTCGGTCTCCGCGCGGACCGACTCCAGCTCCACCCGGGGCTCGTGGTCGCGGACCGCGTCCGCGATCGAGCCCTCCAGGTCGCGCAGGCTCTGCACGCTGCCCGGCGCGAACACCGACTCCTGGGCGCGGGTGCCGAGATCGGGCCGCATCACCCGCTCGCCGAGCGCCGTCAGCAGCAGCGCCCGCAGACAGTGCTCGATGCTCTCCTCGCCGACGGCGTAGCCGAGCCGCCCCGCCTCGTCCGGCAGGACCGGGAAGCGCCAGCCCGTTCCGAGGAAGTCCTCGCTCATGCGCATCTCCCCTTCTTGGCCAGGACGGACGCCGGGTCCAGCGGCACGGCCGGCGGCCCCGTCGGCCCGGCGGCGGACGGATGGGTGTGCATGTTGAACGCCGCGAGCAGCGCGTTCCCCAGCACCAGCGGCTCGGTGGCGCCGCCGCCGAGGTCGATCGCGGGGGAGTCGACGGTCACCCTGGGCGCCGTCAGCGTGATCTCCCCCTGCGCGGAGACGGTCACGCTGCCGCCCGGCGCGGCGGTGATCCTGACCGCCTTGCCCTCGTCGTCCAGCTCCACCACATGCCCCGCCGCGGACGTGATCCGCACGGCGGCCTTCGCCCGGGTGTCGTCGAGGACGACCTCGTGCCCGTGCCGGGTGCGGATGGCCTTCTGGTCGCGTCCCCCGGTGCGCGCGGTGGGTGGCTTGTCCTGGCCGTTGTAGAGCCCGCCCACCACGATCGGGAAGCGCATGTCCCCGTGGACGAAGGCGACCAGCACCTCGTCGCCCTTCTCCGGGACGAACACCGTGCCGTAGCCGCCGCCCGCGTACGGCTGCGCGACCCGGCACCAGTCGGTGACCGTGCTGCCGTCGAACCAGGGGAAGGTGAGTTTGACGCGGGCCTCGTCGTCGCCGTCGTTCTCCACGACGAGCGCCTCGACGACACCGTAGTACCGCTTGTCGGTGGAGCGGGCACGCGGAGTGGTCCTGCTCGTCACTGGTCCCCCTGATGAATCCGCCGGCCGGTGAACTGGGTGAAGAAACCACTGGTGTTGAGGGTGTGCTCGACCCGTTTCACGAAGTACGTCCCGGAGAACCGGCGGCCGAGGCCGTAGATCTCCAGGTTGTCGCCCGGCCGCAGCTCCGGCAGCCCCGCGACCCGGCCGGTCGCGGTGATGAACTCGTACGCCCGCTCCCGCAGCAGGCTGATCGCCAGCTCCCGGGCCTCCTGATCGCTGGAGACCGGGGCGTCGACGACCACCTCCTGACGGCCCTGGAGCGTGCTCTCGGCCACCTGGGGGCCGCTCTGCCCATCGGCCGTGTTCTGCCCGGCGGGCAGGTTCTCGGCGGTGGCGGTGAACGCGATCGCCGCCTTGGTACGGGGGTCCCAGCCCCGCACGGTGACCTTGCTGACCTGCTGGGACACCGTCAGGGTCGGGGTGAAGTCCAGCAGGTTGGGCACCAGCCCCGCGGGCTGGGCGCTCGGCCCCGTGGACAGCCCCGGCGCGTACGCCAGCCGGTACAGCCGGATCGGGCGGCCGTCGCGGCCGTCGGTGGGGCGGATGAAGTGCAGGGTGTCCTGGCCGGAGGCCGCGTCCGGCAGGATGTAGCAGTCGAAGTCGAGCCGCTTGGCCCGTTCCATCAGAAAGCTCGCGTCGTCCTGGTTCTTCTGCACCACCAGGTCGTGGACGGCCCCCTCCCGGGTGACCTCGATCCGGAGCTGATTGCGGAGCGCGATCTGCTCCGCGATCCGCCAGTCCGGCATATTGCGGTAGATCTTGGGCTCGGTCTCGGCCGGTTTGCGGTCCTTCAGCCGCAGCATCCCGTCCACCCCGCTGACGGCGACCGTCGGCGACTCGTTGTCGGAGAACTTCGGACTGAGCGTGCTGATCGTCCCGGTGGCCACGGTGAGCAGCTTGTCCGCGTAGCCGAGCCGCACCGAGACCCGGCCGCCCAGCCGGAACGCGCGCGAGTCGCTGTGCTTGAACCGCAGCCCCACGTCGTCCCAGTTGTTCAGGGTCAGATCGAACCCCGACATCTCCTCGATGTCCCGGTGCACCTTGATGTCGATGACGTCGTTCTTCGTGGACGGGTCCACCTCAAGGCCCTCGATCCGCACCTCGAACTCGGGCGCGTACCGGTCCGGGGAGGCGATCTCGGGCGTGGGGGAGGTCATCGCGGTCCCCTCACGGCAGCCGGGGCACGGACAGCACCCGTCCCGGCCGCAGCTCGCGCGGATCGCTGATGCCGTTGGCGCGCGCCAGCTCCCGCCAGGCGTCCGGCCGCCGGTACACCGCGGCCGAGATGCTGCTGAGGGTGTCGCCCCGGCGCACCACGTACGTCTTGTCCACCGTGGGCGAGGAGAGCGGGTTCCGCGCGGTCTGCGCCGCCGCCGTGCGGTACTCCTTGAGCGTCAGGTCGAGCAGCGCCCGCAGCGGCACCCCGTCCTGGCGGAACATCTGGTACTGCACGTCCAGCTTCTCCACGACCCCCGTGAACACCGACTGGTCCCAGACGAAGCGGACCACCGGCGGCGCGTGCTCCCGGCTGTCGGGGCGCATCAGGTTCCGCAGCGCGTCGACATACGCCGTCCGGACGTTCTCCAGCGTGTCGGAGGTGTCCATCAGCGCCTGGACGCTCAGGGTCTCCGTGCCGCCGCGCACGAACTGGAGCGGCGGGGTTTCCAGCCCCGGGATGGTGATCTCCGCGAACGTGTTGCTCTTGCTCAGCTTGTAGTCGGTCGGGTTGAACCGCAGCGGGATGCGCCGCTGCCGCTCGTCCGCGATCACCGGCCGGACGATCTCCAGCCGGGCCTGGGCGGCGCGCTGCCGGGCGAAGGACACGGGCGTCACACTCACGGCTGTCCCTCCCCGTCCCCGATACGGCGCTCGGAGCGGGTGTGCTCCGCCCGCGCGCAGGCGTTCTCGTACAGCCGCGACCACGCCTGGATGTGCTGGTTGAACAGCCGGGTGAAGACCTTGCCGTCGTCGCCCTCCACCTGGAAACGGACCTCCAGATGGTGAATGATCACCTTCGGCACCCCGGTCACCTCCCCTGGGCCGGCCATGCGGCCGCCGCCGGCACGGCGTCCTGGAGCACCTTCGTCAGCCCCTCGTGCGCGATCTCCAGGGACTCCACCGCGACCGCGTTCTGCTCGCCGTGCAGATCCGGGCCGCTCCACTTGGCCGCGAGCCCGCCGTGGAACGCCCACGCGGCGGCGGGCACCCCGTCCTGGCCGAGCAGGACCACCGCGCCGTCGCGGCGGGCCCCCAGCGCGTCCGACAGACCCGCCTGGTACCAGGCCCACAGCCCCGGGTCACGGACCACCCCGCGCTTGAGGACGATCCGGTTCCAGCTGTGCCGCAGCGGCAGCTGGTGCACCGAGTCATTGCGCCCGCCCTCCGGGTACGCCGTCACCTCCAGTTGGGCGCCCATCCCGGTGACCTCCTGGAACGCCCCCGAGGCCACGAGCGGCAGCAACAGCGCCTGCGCTCCCGGCAGATAGGCGTCCCCGGCGTCCAGCGTCACCAGGAAACGGAACTTCGGCAACGGTTCCAGGGTCATGCCTCGATCACCTCCAGACCGCGGTCCGCGCCGAGGATCAGACGCAGCCGGATGAACTCCATCGGGACGGCCGGGGCGACCGCCACCTCGCAGACCGTCGTGGCCGGGTCCTGCCCCGGCGGGTTGTTGCTGTCGTCGCACACCACCCGGAACGCCTCGTCGGGCCGGGCCCCCGCGAGGGCGCCCGCGCGGAAGGCCGCGAGCAGGACCGAGGTCAGCGCCCGCACCAGCGCCAGCCGCAGCTCGGGCGAGTTGACGTCGAACACCAGTGGGGCCGCGACCCGCCGGATCGCCCGCACCAGCAGATGCAGCAGCCTGCGGTGGGCGATGTACCGGACCCGCGGCACGGGGGAGAGGGTGCGCCCGCCCCAGACCGTGAGCCCCCGGCCCCGGGTGCACCGCAGCAGATCGATGCCCGCGTCCGCCAGCCGCAGCCGCTGCTGCGGCGGGAGCGCCACCGCCAGGTCCACCGCCTCCAGGAGCACCGCGTTGGCGGGGGTGTGGTGCGCCCCGCGCTCCGCGTCCAGCCGGGCGATCACCCCCAGCACATGCCCGGACGCCGGGACCGTGCGCGCCCCGTTGCCCTCCGGCACCAACAGCGGCGGGTGGTACACCGCGGCGGTCGCCGCCGCGTCGCCGTCGCCGGACGCGGTCAGCTCCCCGGCGAAGGCGACCGCGCCGTCCACGGCCGACAGCTCCGGCGGCACGTCCAGCACCACCAGCCGGTCCAGCAGCGGCCGCACGGCCGCCAGCAGCTCCCGCACCAGCTCCCGGTGGTCCGGCCCGGCCAGATCCGTGCCGAGGTCCGGGAGGGCCACCAGCGAGGGCTCGGGCAGCGCCACGAGCCGCACCACGGCGTCCCGGTAGGCGTCCCGGTCCGGCGGGCTGTCGCCGCCCCCGGCGAGCGTCAGCTCCCAGGTACGGGTGATCGGCCCGGGCGGGGCGGCCGGGTCGGCCGCGCCCGCCGGTTCCACGGGCACCAGCCGGACCAGCCGGGACGCCGCCAGCGCCGATTCCAACGCGTCCGGCGCCAGCCCGGGAAACCACTCCGTGGGCTCCCCGGGGACCGCCACCCGCACATCCACCGCCGGGTGCCCGGCGACCGTGCTCGACCGGAAACGGACCGTGATCCGCCCCCCGTTGGCCCACGCCCCCGGGCTGCCGGCGACCACCTCGTACCGCCGGGCGGCGAACCCCGCGACCTCCCCGACCGTCCACCCGGCGCGCGCGGTCCGGCCCGGCCCGGCGACCCGCAGCAGCCACGCCGTGCGCCCGCCGTTCTCGAAGAAGCCGCGCACCGCGTACGGGGCCGACGCGGAGCCGTCCGGCCCCCCGAAGGCGCCCAGCACATCGCGCCAGCTCTCCACCCGCACGGGGGTGCCCACCGGGCCCCGGCGGAACCCGCCCAGGAACGCGGCCACATCCGTGCGCAGCGGTTCCTCGTCCGAGCCGCGCGGCTCGGACGTCAGGGACACCCCGGGGAGCGCTTCGGTCGTCATGTCAGACGTCGATCTCCAGCTTCTCGACCGCCAGCACCAGCGTCTCCATGGCGATCTCGTTCTTCGTGGCGTTCAGGCTCGGCCCGGTGTACTTCGTCGGCCAGCCCCGGTCGAAGTTCCAGCGCATGCACTCCTGGCGGTTCTCGTCCAGCAGCACGATCGAACCGGAGGTGCGCCGCACCTTGCCGTTCAGCGCCTCGACCACCCAGTTCCAGAAGCCGACATGGCCGGTGATCCCGCGCTTGAAGGTGAGGTTGGTGAACTTCTTCAGCCCGGGGATCTTGCGGACGGTGGTGTCCTCGCTCCCGTTGCGGTACTCGATCACCGGAATCTCCAGTTCGAGTCCGCTGGCCTCGGTGAACGAACCGCTCACCGCGACCCCGTCGTCGCTGACGTTGGTCACGATGATCTGGAAGTTGTATGAGGCATAGGGGTCGTCCCTGGTCACAGGGGGCATGGTGGCTCTCCTCGGCTTGTCCGTCGGCTGCTCAGGCGGTCTGGGTCTCGCGGGTCTTCTGCTGGATCCGGAAGATCACGAACTCGGCCGGGAAGACCGGCGCGACACCGATGACGCAGATCAGCCGGCCGTTGGCCAGATCGTCCTCGGTCATCGTGGTGCGGTCGCAGGCGACGAAGAACGCCTCGTCGGCGGTGGTCCCGGCGAGCGCCCCGCTGCGCCACACCGTGGTGAGGAAGTTCGTGACCGTCTGACGCACCAGCGCCCACAGCGCCTCGTCGTTCGGCTCGAACACCACCCACTGGGTGCCCTCGTCGATCGACTCCTCCAGGAAGAGGAAGAGCCGCCGCACATTGATGTACTTCCAGGAGCTGTCCGACGACAGGGTGCGCGCGCCCCACACCCGCTGCCCGAACCCCGGGAAGAACCGCAGCGCGTTGATCCCCTTGGGGTTGAGCAGGTCCTGATGGCGCTTGGTCACGTCCTGCGCGATGCCGTCGACCGCCCGGATGCCCCGGATGACCGTGTTGGCCGGGGCCTTGTGCACCCCGCGCTCCACGTCCACCCGGGCGTAGATCCCGGCGAGATGGCCCGACGGCGGCACCTCGACATCCCGGTTGACCGAGGGGTCCCGGGTCACCAGCCACGGGTAGTACAGCGCCGCGTACCGGGTGTCGAAGCGCTCCCGGAACGCCTGGATGCCCTCCAGGTCGAGCCCGTCCTGCGGATCGAGCACCGCGAACCGGTCCCGCAACAGCTCGCAGTGGGTGACGAGGGCCGACTCCACCGTGCCCGACCACATCGCGGGCACCGCGCAGACGGACACCTCGTCGATGTCCTCCAGCGCCACGATGCCGGTCCGCCGCCCGCTGCCGCCGTCCGTGCCGGTGAAGTCGGCCACGCTCAGCCCGGGATAGGCGTCGTCGCCGCCCTCCAGCGCCAGCCAGGACCCGATCGCGGGCACCGGGAACTCGGCCGGGTCGGTGGAGAGGCCGGGCAGCGCCGTCGCCCGCACGAGCTGGGAGCGGGCCGCCAGCACCGAGGGCAGCCCCGTGTCGGCGTCCCCGGTCAGCCGCAGCCCGCCGAAGCTCTCCGTCACCTGCGCGCCCGTCGCGTCGGCGTACCGGGTGTCGACCTGGGCCTCGACCAGATGGAGCCGGTCCGTCTCGTAGCAGGTCCCCGGCACGTCGCCGTCGAAGGTGACGAGGTCCGCGTCGATCGCGGCGACCCTCCGCACGGTCAGCGCGGCGCCGTCGTCGAACTGGGTCACCGCGCCCGGGTACAGCCTGCTCGCGCCGCCGATCCGCAGCTTCGGCCCGGTGGCGACATTGCCCCGCCGCACCCGGCGCACCCCGAGCCCCGCCTGCCACGCGGGATGGGGGGTGTTCGCCGGGAAGGTCAGCCGGACCGTACCGGCCGCGGGCTGCCCCACCTGCACCGGGTACCGGACGTCCCCGATCTGCGCCCACACCTCGCCGGGCAGGTCGTCGGGGTCGAGACCGGTCACCGACGCCACGTCCACGGTGGCGCTGTCCGCGTCCGCGTCCGCGAGCAGCCGGGTGACGAACAGCGCGCCCTCCTGCGGGTCCGGGAGCACCGGCAGCGCCGCCGACACCACCGGCTGGATCCGTACCCGCGCCGCGTCGCCCCAGGCGCCGGGGGAGACCGCGGCGAACCGCAGGCCCGCCTCGGTGGAGCGGGTGCCGACCTGGACGTAGTCCCCGCGTGCCGTCCTGACCTCGGCGGGCAGCGGGGTGTCCAGCACGATCCGCCGCCCCGTCCGGTCGTACGAGGCGATCCGCGCCGTGTGGATCGCCTGCTGGTCGTCCCCGCGCAGGATCTGGACCTGCTGCCCGACCCCGCTGAAGCCGATCAGATGCCCCAGTTGCAGACCCCGGGCACCGCGGGCCGCGTCCGCCGCGACCGGGCTCACCAGACCCCGGCCCAGCGTCCCCGACGAGGGCACCGCCCGCGCGCTGACGACCCGCTTCACATACAGCCGCTGGCCCCCGTTGTCGAAGAACCCCTTGACGGCCAGCGGGAAGAGCCACCAGCGGCCCCCCTCGGCCGGGTCGTTCGCCCAGGTGTCGCGGACGGTCGCGGCCGGCTCCGGCAGAAAGCCGCCGAACGTGTTCTGGAACTCCAGGAACGAGGTGACCAGCTTCGGCTTGCCGGACGAGGGGCCCCGGGCCGTCACCCCGACCATCCCCGCCGTGCTGGTGCTCACCCCCGCGATCGGCCGCGGCCCCGCGTCGATCTCCTCGATGTAGACACCGGGGCTCAGATACTCCGCCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP016559|6772467:6787533|6784781_6785237_-|WP_003959210.1|tail|DBSCAN-SWA
MPPVTRDDPYASYNFQIIVTNVSDDGVAVSGSFTEASGLELEIPVIEYRNGSEDTTVRKIPGLKKFTNLTFKRGITGHVGFWNWVVEALNGKVRRTSGSIVLLDENRQECMRWNFDRGWPTKYTGPSLNATKNEIAMETLVLAVEKLEIDV
>NZ_CP016559|6772467:6787533|6781903_6782575_-|WP_003959158.1|DBSCAN-SWA
MSVTPVSFARQRAAQARLEIVRPVIADERQRRIPLRFNPTDYKLSKSNTFAEITIPGLETPPLQFVRGGTETLSVQALMDTSDTLENVRTAYVDALRNLMRPDSREHAPPVVRFVWDQSVFTGVVEKLDVQYQMFRQDGVPLRALLDLTLKEYRTAAAQTARNPLSSPTVDKTYVVRRGDTLSSISAAVYRRPDAWRELARANGISDPRELRPGRVLSVPRLP
>NZ_CP016559|6772467:6787533|6779609_6780014_-|WP_003959155.1|DBSCAN-SWA
MSEDFLGTGWRFPVLPDEAGRLGYAVGEESIEHCLRALLLTALGERVMRPDLGTRAQESVFAPGSVQSLRDLEGSIADAVRDHEPRVELESVRAETDPVDGSRVTVSVEYRVRRSNTKANLVFPYYTGLLGSTP
>NZ_CP016559|6772467:6787533|6782571_6782784_-|WP_003959159.1|DBSCAN-SWA
MAGPGEVTGVPKVIIHHLEVRFQVEGDDGKVFTRLFNQHIQAWSRLYENACARAEHTRSERRIGDGEGQP
>NZ_CP016559|6772467:6787533|6775615_6777670_-|WP_003959214.1|plate|DBSCAN-SWA
MTDGVWWERGARAEGRMVPGPGPSGVQPELVDATREAVRGAVRGRIAGYTPDWTASDRQDAGVALVRLFGTQAEPVLSRVNRLPEKILAEHLATAGVRRRPAGPAAALLEFTVNPPDGASVLVPAGFQAAAPGPDGQVVYETDDDLYATPATVAALAVQEAGTPEQLPLGPAGPGRPFAPFGRDPRPGDGLWIALAGAAAPYPRLSLGLVVVAVPPAPARSGGAELPPPAGPLLEWDVLDGTRFVPAEVVRDGTDGLRGSGTVELRVPRTWAPGTPAGFRQGPPLRWLRLRIAHGAFDGPGPVVSGLRLNTVAATAARTVRDEPLQPVQDVSGAGRRVLRLSQVPILAGSLVIEVDDDTGGDVFGTTVPTAARWQEVESLAAYGADDRVFTVDHATGEVAFGDGVHGAAVPPGFRNVRAVRYRVGGGAAGTVAAGAVNAVVTALPFVLGVTNPFPASGGEDAEPDAEAIRRGVGELRARGRAVAPADYGLLATRAPGAAVARARGVPGLHPGYPGVAIPGVVGVLVVPEPLPDADPAAGPPLPTAAALQAVADFLTGTVAPAGVTVVAAPVAYRRVAVEAWVTLDPDQDRSAVLARAGDAVTGYLDPLRGGDDGAGWPFGGALRHTPLVRRLLTVDGVLSVSRLSFTVDGVRLPACADHPIGADRLVWPERPLLIPVEDTGAPS
>NZ_CP016559|6772467:6787533|6780010_6780715_-|WP_003959156.1|DBSCAN-SWA
MTSRTTPRARSTDKRYYGVVEALVVENDGDDEARVKLTFPWFDGSTVTDWCRVAQPYAGGGYGTVFVPEKGDEVLVAFVHGDMRFPIVVGGLYNGQDKPPTARTGGRDQKAIRTRHGHEVVLDDTRAKAAVRITSAAGHVVELDDEGKAVRITAAPGGSVTVSAQGEITLTAPRVTVDSPAIDLGGGATEPLVLGNALLAAFNMHTHPSAAGPTGPPAVPLDPASVLAKKGRCA
>NZ_CP016559|6772467:6787533|6772467_6774444_-|WP_065757207.1|tail|DBSCAN-SWA
MSCVPGPATFRLLDAWTGWDPYTGPEEPGVSGIVGLDDPEGIRLARRGVPDGPTRGELLPWFPDRRLAPGCRAGDWYLLVPGKRPGLLRRDVCGGGWLPVWPPACGPVPLVRPWSVAARSHRLVVVEPGRVLVWDREGGRLTAVIDVDGARWAAPAPRGEILVARRGTTALRRYGPDGRLREVLRTGAAGAVAGLRAAPDGTIWLLTEDGGVPRVHRGGRGRPFRPATAAELAAALPPSTLAAADADGFCLREPGPEEPVTSCWTWHGGPRTTPPAPTADLVTSGHLLTALIDSGIARCRWHRVRLDADLPPGTAVTASIVVTEDGGCADSDWQHAAPGLTDFLVDQPPGRFLRLRLRLTGDGSATPVVRRVRLDFPRVTGADLLPPAFREDPAADDFTERFLSLFDATLAELDRTIERAPALLDPAGVPDRALPWLAGLLGLSYESGWDAATRRALLAAAPELYRRRGTPWALREAVRIVFGVAPVIDELAADRRWAQLRPPGAAAGAAGAGEGLGTVRLFGRAAGRFRVGGSALGAAPLRAFGDPDADPLTAQAHRFRLLLPAGAADGAALARLVRRQAPAHTVGSVRAGGSGLVVGSRSTVGVDTAFVPLPPPVLGGARPLRLNRDGVLRPGPRGARRGVGVGVAAAVGVHTQLS
>NZ_CP016559|6772467:6787533|6785268_6787533_-|WP_003959209.1|tail|DBSCAN-SWA
MAEYLSPGVYIEEIDAGPRPIAGVSTSTAGMVGVTARGPSSGKPKLVTSFLEFQNTFGGFLPEPAATVRDTWANDPAEGGRWWLFPLAVKGFFDNGGQRLYVKRVVSARAVPSSGTLGRGLVSPVAADAARGARGLQLGHLIGFSGVGQQVQILRGDDQQAIHTARIASYDRTGRRIVLDTPLPAEVRTARGDYVQVGTRSTEAGLRFAAVSPGAWGDAARVRIQPVVSAALPVLPDPQEGALFVTRLLADADADSATVDVASVTGLDPDDLPGEVWAQIGDVRYPVQVGQPAAGTVRLTFPANTPHPAWQAGLGVRRVRRGNVATGPKLRIGGASRLYPGAVTQFDDGAALTVRRVAAIDADLVTFDGDVPGTCYETDRLHLVEAQVDTRYADATGAQVTESFGGLRLTGDADTGLPSVLAARSQLVRATALPGLSTDPAEFPVPAIGSWLALEGGDDAYPGLSVADFTGTDGGSGRRTGIVALEDIDEVSVCAVPAMWSGTVESALVTHCELLRDRFAVLDPQDGLDLEGIQAFRERFDTRYAALYYPWLVTRDPSVNRDVEVPPSGHLAGIYARVDVERGVHKAPANTVIRGIRAVDGIAQDVTKRHQDLLNPKGINALRFFPGFGQRVWGARTLSSDSSWKYINVRRLFLFLEESIDEGTQWVVFEPNDEALWALVRQTVTNFLTTVWRSGALAGTTADEAFFVACDRTTMTEDDLANGRLICVIGVAPVFPAEFVIFRIQQKTRETQTA
>NZ_CP016559|6772467:6787533|6777666_6779613_-|WP_003959213.1|DBSCAN-SWA
MTLPPPRLDDLTWADMMAAVRRRIPAESDGRWTLHAPVDPGVTLLELFAYLLEQRLYWLDQVPDALVVAILRLLGSDPPRPAVPAATVLRLTAEWPDTAVPVVPAGTALSRDPRGLIPFCLDDDVAVYPLDPSAGITVVTDRDRTADLRTGRPVALLAADGGPARVALTLPLAGAHPAPGPLSLLFGLDAPAACVPSWLPGAVGDVPPPAELTWSWFRPGTDRAGAFARVDDGTAGLRRPGVVRLHPPADWTTLDRGVLLTADAATFAAPPRLLRLDVNVSAARNRRRRTATAREVAEQTEAWLKLPGQRLVLPDAGGRLLDAAAVIAGQEWRPVPDFTFGAPGDRVFTLDRAAGALVFGDGLTGAVPRPGDEVHVVYGLGGGREGNGGLTDNWLPADGPIARRGALSGANPVQAAGGADPETVAGARDRAGGSLGEVTRAVTAEDFVTLARTTPGVAVARAHASVGEHPGFPCAAVPGAVTVRIVPGVPRDDDPAGQVAAPVPDPGALCAVARRLAGARLLTSEVFVRPPDYREVALRVDLAGAPADRARVAAVLTAALRRHLDPLVGGEDAGGWPFGGPLRPAALLRAAQRALGDLAEVAGVAIGLDGAAPGEDCRDVRLRAAELPVLRSVRTRVSAASGGGEGLE
>NZ_CP016559|6772467:6787533|6783277_6784780_-|WP_003959211.1|tail|DBSCAN-SWA
MTTEALPGVSLTSEPRGSDEEPLRTDVAAFLGGFRRGPVGTPVRVESWRDVLGAFGGPDGSASAPYAVRGFFENGGRTAWLLRVAGPGRTARAGWTVGEVAGFAARRYEVVAGSPGAWANGGRITVRFRSSTVAGHPAVDVRVAVPGEPTEWFPGLAPDALESALAASRLVRLVPVEPAGAADPAAPPGPITRTWELTLAGGGDSPPDRDAYRDAVVRLVALPEPSLVALPDLGTDLAGPDHRELVRELLAAVRPLLDRLVVLDVPPELSAVDGAVAFAGELTASGDGDAAATAAVYHPPLLVPEGNGARTVPASGHVLGVIARLDAERGAHHTPANAVLLEAVDLAVALPPQQRLRLADAGIDLLRCTRGRGLTVWGGRTLSPVPRVRYIAHRRLLHLLVRAIRRVAAPLVFDVNSPELRLALVRALTSVLLAAFRAGALAGARPDEAFRVVCDDSNNPPGQDPATTVCEVAVAPAVPMEFIRLRLILGADRGLEVIEA
>NZ_CP016559|6772467:6787533|6782762_6783281_-|WP_003959160.1|tail|DBSCAN-SWA
MTLEPLPKFRFLVTLDAGDAYLPGAQALLLPLVASGAFQEVTGMGAQLEVTAYPEGGRNDSVHQLPLRHSWNRIVLKRGVVRDPGLWAWYQAGLSDALGARRDGAVVLLGQDGVPAAAWAFHGGLAAKWSGPDLHGEQNAVAVESLEIAHEGLTKVLQDAVPAAAAWPAQGR
>NZ_CP016559|6772467:6787533|6780711_6781893_-|WP_003959157.1|DBSCAN-SWA
MTSPTPEIASPDRYAPEFEVRIEGLEVDPSTKNDVIDIKVHRDIEEMSGFDLTLNNWDDVGLRFKHSDSRAFRLGGRVSVRLGYADKLLTVATGTISTLSPKFSDNESPTVAVSGVDGMLRLKDRKPAETEPKIYRNMPDWRIAEQIALRNQLRIEVTREGAVHDLVVQKNQDDASFLMERAKRLDFDCYILPDAASGQDTLHFIRPTDGRDGRPIRLYRLAYAPGLSTGPSAQPAGLVPNLLDFTPTLTVSQQVSKVTVRGWDPRTKAAIAFTATAENLPAGQNTADGQSGPQVAESTLQGRQEVVVDAPVSSDQEARELAISLLRERAYEFITATGRVAGLPELRPGDNLEIYGLGRRFSGTYFVKRVEHTLNTSGFFTQFTGRRIHQGDQ

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065757207.1|6772467_6774444_-|tail	phage tail protein	NA	NA	NA	NA
WP_003959214.1|6775615_6777670_-|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_003959213.1|6777666_6779613_-	hypothetical protein	NA	NA	NA	NA
WP_003959155.1|6779609_6780014_-	GPW/gp25 family protein	G8EXQ2	Synechococcus_phage	4.4e-05	30.6
WP_003959156.1|6780010_6780715_-	hypothetical protein	NA	NA	NA	NA
WP_003959157.1|6780711_6781893_-	phage late control D family protein	NA	NA	NA	NA
WP_003959158.1|6781903_6782575_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_003959159.1|6782571_6782784_-	hypothetical protein	NA	NA	NA	NA
WP_003959160.1|6782762_6783281_-|tail	phage tail protein	T2KT02	uncultured_phage	1.4e-08	35.3
WP_003959211.1|6783277_6784780_-|tail	tail protein	H6WFT7	Cyanophage	6.9e-11	29.6
WP_003959210.1|6784781_6785237_-|tail	phage tail protein	NA	NA	NA	NA
WP_003959209.1|6785268_6787533_-|tail	tail protein	J9PVC2	Bacillus_phage	1.4e-47	32.2

2. NZ_CP016560

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016560_1

• CRISPR_ID: NZ_CP016560_1
• CRISPR_location: 161315-161404
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP016560_1

Consensus_repeat	Method
CGGCACCGTCACCCGGCGCGGGGT	CRISPRCasFinder

spacers of NZ_CP016560_1

>1.1|161339|42|NZ_CP016560|CRISPRCasFinder
ACACGGACGCGGCGACAGCCGGGGCAGGCGCCGGAGATGAGC

CRISPR arrays and Neighbor proteins around NZ_CP016560_1

CRISPR arrays

The CRISPR arrays of NZ_CP016560_1

>merge|NZ_CP016560|1|161315-161404|CRISPRCasFinder
CGGCACCGTCACCCGGCGCGGGGTACACGGACGCGGCGACAGCCGGGGCAGGCGCCGGAGATGAGCCGACACCGTCACCCGGCGCGGGGT

>NZ_CP016560|1|1|161315-161404|CRISPRCasFinder
CGGCACCGTCACCCGGCGCGGGGT	ACACGGACGCGGCGACAGCCGGGGCAGGCGCCGGAGATGAGC
CGACACCGTCACCCGGCGCGGGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016560.1|WP_003953103.1|153039_153510_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003953101.1|156131_156752_-|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|376808
NZ_CP016560.1|WP_003953100.1|156825_157425_-|riboflavin-biosynthesis-protein-RibD	unknown	unknown	gnl|CDD|223340
NZ_CP016560.1|WP_003953104.1|152302_153043_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003953105.1|151093_152032_-|hydroxyurea-phosphotransferase	unknown	unknown	gnl|CDD|309685
NZ_CP016560.1|WP_003953098.1|158581_159136_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003953099.1|157511_158453_-|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|176856
NZ_CP016560.1|WP_003953096.1|161827_162157_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003963325.1|164816_165284_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239217
NZ_CP016560.1|WP_003953102.1|153523_155746_-|DUF1906-domain-containing-protein	unknown	unknown	gnl|CDD|119380
NZ_CP016560.1|WP_003953095.1|162458_163223_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003953106.1|150486_150942_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003953085.1|173210_173780_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NZ_CP016560.1|WP_106432070.1|167696_169811_+|AfsR/SARP-family-transcriptional-regulator	unknown	unknown	gnl|CDD|276938
NZ_CP016560.1|WP_003953092.1|165348_166398_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP016560.1|WP_003953088.1|170770_171244_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003953086.1|171803_172850_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NZ_CP016560.1|WP_003963324.1|163275_164787_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016560.1|WP_003953107.1|149342_150404_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132005
NZ_CP016560.1|WP_003953087.1|171361_171736_+|hypothetical-protein	unknown	unknown	gnl|CDD|319937

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016560.1|WP_003953099.1|157511_158453_-|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	8.5e-11	37.0	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016560.1|WP_003953101.1|156131_156752_-|NAD(P)H-dependent-oxidoreductase	gnl|CDD|376808	pfam02525, Flavodoxin_2, Flavodoxin-like fold. This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.	3.07362e-13
NZ_CP016560.1|WP_003953100.1|156825_157425_-|riboflavin-biosynthesis-protein-RibD	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	3.42622e-14
NZ_CP016560.1|WP_003953105.1|151093_152032_-|hydroxyurea-phosphotransferase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	1.06205e-58
NZ_CP016560.1|WP_003953099.1|157511_158453_-|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl|CDD|176856	cd07814, SRPBCC_CalC_Aha1-like, Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Micromonospora echinospora CalC, human Aha1, and related proteins. Proteins in this group belong to the SRPBCC domain superfamily of proteins, which bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. MeCalC confers resistance to the enediyne, calicheamicin gamma 1 (CLM), by a self sacrificing mechanism which results in inactivation of both CalC and the highly reactive diradical enediyne species. MeCalC can also inactivate two other enediynes, shishijimicin and namenamicin. A crucial Gly of the MeCalC CLM resistance mechanism is not conserved in this subgroup. This family also includes the C-terminal, Bet v1-like domain of Aha1, one of several co-chaperones, which regulate the dimeric chaperone Hsp90. Aha1 promotes dimerization of the N-terminal domains of Hsp90, and stimulates its low intrinsic ATPase activity, and may regulate the dwell time of Hsp90 with client proteins. Aha1 can act as either a positive or negative regulator of chaperone-dependent activation, depending on the client protein, but the mechanisms by which these opposing functions are achieved are unclear. Aha1 is upregulated in a number of tumor lines co-incident with the activation of several signaling kinases.	1.76413e-13
NZ_CP016560.1|WP_003963325.1|164816_165284_+|NUDIX-hydrolase	gnl|CDD|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	2.19473e-19
NZ_CP016560.1|WP_003953102.1|153523_155746_-|DUF1906-domain-containing-protein	gnl|CDD|119380	cd06418, GH25_BacA-like, BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of Bacillus subtilis. BacA has a C-terminal catalytic glycosyl hydrolase family 25 (GH25) domain and an N-terminal peptidoglycan-binding domain comprised of three alpha helices which is similar to a domain found in matrixins.	2.85629e-71
NZ_CP016560.1|WP_003953085.1|173210_173780_-|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	5.46431e-22
NZ_CP016560.1|WP_106432070.1|167696_169811_+|AfsR/SARP-family-transcriptional-regulator	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	1.0645e-43
NZ_CP016560.1|WP_003953092.1|165348_166398_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.85503e-10
NZ_CP016560.1|WP_003953086.1|171803_172850_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	0.00309854
NZ_CP016560.1|WP_003953107.1|149342_150404_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|132005	TIGR02960, probable_RNA_polymerase_sigma_subunit, RNA polymerase sigma-70 factor, TIGR02960 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family.	1.00376e-163
NZ_CP016560.1|WP_003953087.1|171361_171736_+|hypothetical-protein	gnl|CDD|319937	cd08349, BLMA_like, Bleomycin binding protein (BLMA) and similar proteins. BLMA also called Bleomycin resistance protein, confers Bm resistance by directly binding to Bm. Bm is a glycopeptide antibiotic produced naturally by actinomycetes. It is a potent anti-cancer drug, which acts as a strong DNA-cutting agent, thereby causing cell death. BLMA is produced by actinomycetes to protect themselves against their own lethal compound. BLMA has two identically-folded subdomains, with the same alpha/beta fold; these two halves have no sequence similarity. BLMAs are dimers and each dimer binds to two Bm molecules at the Bm-binding pockets formed at the dimer interface; two Bm molecules are bound per dimer. BLMA belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. As for the larger superfamily, this family contains members with or without domain swapping.	8.62736e-20

Protein sequences

>NZ_CP016560.1|WP_003953098.1|158581_159136_-|hypothetical-protein
MGDIDDALIRADQELFTREPPKSTQARVRFLLGRLKTTKAVAEAIGVTRRSVERYLSGERRTPPRPIADRIEKEVRLRWQPRVRERRRREAAARTGITVETRARFGYTAPIGTTDDPRMRRLTVHLPPQYADRLFTAQHEGAAERRLREIVAEGLQRVYFRDEGARAAGLDVEITDIDYLDLSY
>NZ_CP016560.1|WP_003953099.1|157511_158453_-|metalloregulator-ArsR/SmtB-family-transcription-factor
MTAQKYSLTRIFSVTNTKAMDALLTALADPARWRLVALLAERPRPVGVLARLAEARQPQTTKHLQTLERAGVVTSQRSGQRRVYTLRPAVLRELAAELDRLADAADRATGAGTAHDRYGLSLHTERSTAREAGEGWADGRSFRFLRPLAAGIGPVWRHLTESPLLAHWWTPDELRVSELVFEPRPGGRIVLEYRDTEDTDGSDPVVGRAEGTVDDVRPGERLSYRLSPLLPDGGTAFTAQVDLDLRPMGTGTGTGTGTGGTGAGTELDVHYRITGSTADSADFVAGIEIGFGQSLDRLRETLAEGPAEAPDTS
>NZ_CP016560.1|WP_003953100.1|156825_157425_-|riboflavin-biosynthesis-protein-RibD
MPQQTSRRRVVTNIALSLDGRYAGPDPLDSGWVLPYAVTDVASDHLTSLWTPATTALLGRVNAEGFLAHWPTVIGAEGTDPRHEAFARWLVDTDKVVLSSSRTEAPWERTTLVDKPAAEVVDELKETDGGDILVLSSASVIKPLLAADRVDRLALTVFPVFLGAGPRLFDADLPAGKWSLVSEAAGEHGTLCLVYDRVR
>NZ_CP016560.1|WP_003953101.1|156131_156752_-|NAD(P)H-dependent-oxidoreductase
MITDEHPWTGRSFLFLLGSSRPGGNTETLARAAAEHLPADIPQRWVDLNELPLPDFQDGRHETGEWPVEETEQMLREATLEATDVVLATPLYWYTVSAQTKRYLDYWSGWLGTPGLDFKKHMAGRTLWGVTVMAERQENRADTLTETLNSTAAYMGMRFGGVLLGNGSRPGQVRNDERALRRAEDFFHREAPLAEFPRVESTAGVV
>NZ_CP016560.1|WP_003953102.1|153523_155746_-|DUF1906-domain-containing-protein
MADEMVRRAQAFINAAYDGKLGIGHLPENGETGWKTMFALTRALQYELGIATLSDTFGPTTLSTLQTKYPILNASTVPSANFARIIQSALYCKGYDGGEIDGRYNSRVIASILKLKQNMGVDFAYPGSDLVPKVFKGLLNMDAYTTVNGGSNTIRGVQQWLNGNYVHRRDFFIIPADGHHSRDVAKSMLFAVQYELGMADGTANGVFGPGTQAGLKNHPVASGDSNTWVRLFSAGMVLNQRPTAFTGTFTSALASAVSDFQAFVKLPVNGRGDFSTWASLLVSHGDQSRKGAACDGVTRITPERAATLKAEGITYIGRYLTNPTGGKPYEKEIQEGELATIAANGLRCFPIYQTYGRDASDFSYIAGRTAGQAAINAALDHGFKPGTRIFFAVDFDALLEDIVNNVLPHFKGIQDAIADDGNRFQIGAYGPRNVCTRVAEAGHSTASFVSDMSSGFSGNFGYPLPADWAYDQIVTRTVGTGAGSIEIDVNIASGRDTGQGTFNTPRTAKPDTRLDPSVTTAMMTDVGKYMESLGYPNSGGTRSYQHWKCFQTTVLDHDQVITELSNRHKMRKALIQTTAYWEMRHIDPADEAAWATVIAAFNTTGKYIRDTSTGIAKQRAVTLIGAWNHGLTKGYVTGRPILDVGRDEDKYNIWKKAYDDQAFALTSVAVIHMWDIDGKPGGDDNSPAIGPPRLNFNDREIYEVLRRYQGPPVEPALGEAKKRMGLYYIMEKYNSISRNV
>NZ_CP016560.1|WP_003953103.1|153039_153510_-|hypothetical-protein
MSGDAPYESHNPVLLLLLLLTGVIATPWLAVRAGLLLARTGARRTRRTLLKGAVALAWAGMIGMYTWGLLHLFFLDESNQAKACQETLGPEKIKNLNGYESSFVPLRFGCRTESGRTYEAAIPGYVNPVTGLLGVTSIVLTGYAIRSDKKLEETTT
>NZ_CP016560.1|WP_003953104.1|152302_153043_-|hypothetical-protein
MTVKISRRTALRRAAFVAVGAAVASQAISLPARAAASGPDPNEIREAVRKAQERNKRVLTGVPSKNGWEMEKVADGNGNIHTRPVPGLPFGIQVRMGDAETVLVHVLQRFHYEVDALRDGDVIGWRAPGTVRKGLAESNQASGTAVRIRPGSYPFGARGGFYPLEEQAIRDILADCEGVVRWSGDDRKPDESLFSVDVPPGDERLTRVAEKIRGWHFTPGSGSGVLVDPLQPQRRASARRLAARQV
>NZ_CP016560.1|WP_003953105.1|151093_152032_-|hydroxyurea-phosphotransferase
MSSSTLIDVPDVFAASYGTQGPEARAWLVELPRIGGEFLDRWRLRPDGPPAHGMASLVLPVLREDGTPAVLKLQQLREETAHTATGLLAWRGEGVVRLLDHDERSATQLLERLDAARTLSSLDDDDTAMAALAGLLARLTAVAAPIGVRKLSGIAAAMLERTPEAVTRLGDPAERRLVEVCASAVAELIGESGDRLLHWDLHYDNVLAARREPWLAIDPEPLAGDPGFELLPALDSAWEKVAASGGPGVTRTVLRRFDLLTGALGLERDRAVGWTLGRVLQNALWDIEDGKVALEPTQVAIATALLEHRSAR
>NZ_CP016560.1|WP_003953106.1|150486_150942_+|hypothetical-protein
MTDNRYGTPATRADLELRALHRLAGPWRVSGGATGTVTYRWLEGGHFLAQDIDLTQNGQRIVGMEIIGRSKPFGAEKPGEDILSHFYDNEGNTFDYVYDPSDDGDTLTIWAGEKGSPAFYQGTFSPDGDTLSGSWTYPGGGGYSSVMTRVR
>NZ_CP016560.1|WP_003953107.1|149342_150404_+|sigma-70-family-RNA-polymerase-sigma-factor
MWSSAEDQRTAEAIRAGDQSAFGELAARHRHELHVHCYRMLGSFTEAEDMVQETLLRAWDKRTTFEGRSGFRAWLYRIATNACLDTLARRRRRTTAAVDSGGGPAASVAAEVTWLQPCPDRLLDLAAPAAAEPETAAIGRETIELAFLAAIQHLPPRQRAVLVLRDAAGLPAQETADTLEMSVPSVKSALQRARATLREHLPEKRTDWNAATGPTPAERALLDRYVAACRRSDLPALTALLHEDARQCMPPAHLVFSGREAILDMWRPVLEGEGSWGVWYSRTLEVNRQPAAVNYVRRPGAERYTAVNIDVLRIENGLITDITTFGPELLPAAGLSATLDPADLDPADPDPGM
>NZ_CP016560.1|WP_003953096.1|161827_162157_+|hypothetical-protein
MAGAVSAAAESVRIRPALAPRSAPTGHRGVFRSFTSWHPTVPDQWQPTADRRHSGAGSHIPPRSSAGSRTARPPATATATTPPASIRTQPRTTVPTGYRRVGSRVDGMP
>NZ_CP016560.1|WP_003953095.1|162458_163223_+|hypothetical-protein
MHTRTRDEYGPRAKPSYPVCCRPHRYGERDPALRRSARCGALGGVHGGEEWGGVFTHAGQYPGSALVAGALDQLRARRTHRLLRQETERLVASLPLPRPFDLSRFVGNLEEARGRRIVMKPMPAHLAGLTGFCGLWIKHDTRPLDLILHLTGGSPSHELQIKVHELVHLWAEDATGVVGTDEVLRDLTPARVRELIASGQAAGRHRYDTAVEKRTEDAATLISQRALNPPLIEDSVARRLAEDFSYPFGSDTAL
>NZ_CP016560.1|WP_003963324.1|163275_164787_+|hypothetical-protein
MSVTDAFSYAIAGLLILQPLLRAKSAWNGHRRERSLWGFFAALAVSWLCRTSEVKALLDRTGVLDLSYLFKHVTAIIGICVLLRYVTAVYAETGRTTGHPAGHSTGLPGDRTGSDHGADHGADRRRSARVSAVVHRIATRASAGTIAVMAATFFFLLHPPDTAAPSFLERHEGDPGLPVYMGLFYLYMGTAAAVCAVQWGGAARVTPVRSVRVGMLMMSWAMALAVVYVLLRTAFVVTVSFTTVPDDISRTQEAVTDSLLYLFSVLWGVGAIAPLARAGSYRYRAVRSLLSLHWLWRDLATAAPDVVRHRPSRLFARLPVVGRPLDTFRDVFTSPDPSLLVRVSRYTVDIRDCIFELRRQAPTDLAERARDHVRSLPHGTFGTDGTPGTDGPFGDGAFGDGTLGDGTPGGNRAHGTDRARGTAGREGHDPEILAEALWIRSALLYRAPSPPGPPRSVPAPYPFDPGTDPRQEVPHLRAVACAYGRVRACDVRAVLARATADCA
>NZ_CP016560.1|WP_003963325.1|164816_165284_+|NUDIX-hydrolase
MTNPLARPTMSAGALLDNGKGEYLIVKPGYKEGWNLPGGGVDEGETPRQACERELREELGIEQTPGRLLVSTYVQTADGGHIYWIFDGGTLTPEQQQAIVIQESELTAFRFSGPDDISPTDIPPSRRPLWDAALGALRDGGSVHLEVAGPRPERR
>NZ_CP016560.1|WP_003953092.1|165348_166398_-|helix-turn-helix-domain-containing-protein
MICSRGSRPSSAHSRSNPMPDRIFDGNKLRDYRVIRRMSQSDLAAALDIRTNAVYRWENGLATPPQERLPGIAAMLGADLDELFPRPAPPNLADLRCDAGMRQSDTTRYTNSMSPMPIRAAEQGRRALSDEAVTALARAYNVTRAELLAAQRRSFGFDQPAVPEQTAPTAPTALVAQGARARRGDHPSAGTRVEPGRQEQAGRQSKEMPAQAATTIAEKIAYLRAELHGGTGPSDADLAVAGNGRGGPAVLTERLVRELRTGRRTTAPDGVLDALALAFDVPPVYFRSSDPGVHRLVVSARAVHNEFTIMAARGGEQEISREARDQLRDFISDTMAEILGTGEDEPRTP
>NZ_CP016560.1|WP_106432070.1|167696_169811_+|AfsR/SARP-family-transcriptional-regulator
MFQRSDPTAAPPGRPVDRNRGVYVEFQLLGPVEVRDEGRPIALSGSKMHTALAALLLARGRVVSDERLSELLWGLRPPATRNAQIYTHISRLRQRLGPSVGLTRRQPGYRLVTDGAHVDAFEFERLERLGRTALEERRFAQAASVLRRALDLWQGPALGNVTPYLAEVELPRFEEARMSVLEDRIGAELALGRHGPLTSELTWLVGEFPLRERLRAQLMTALYRCGRQAEALHVYHEGREVLTEELGVDPGSDLTAAYQAVLSRELDNLPQPARVVLQEPPAGAAAPLVTLPSATADFTGRTAELDQVRERLAPSPGHRPTAFGPRRLLVSGMPGVGKTALAVQAAHTMAEEFPDGLLHLRLRAADGTPADCGDVLTGLLRQLGESPERLRAPDGDRLRLDDLIHRCRTLTAGRKLLVLLDDAVNELQLEPLLPATADAAVLVTSRNQFSMGPGSWTVTLEPLTTEESFGLLAAVIGDARVRAEPEAAREVVEACARLPLALRAAATRLAVRPHWPVARLARRLADPAARLAELRVGTLDVRRVLSAALGRRQEREVELIHRLVHCADGEFTASQAALPLFGLPGEVAEERAEDFLERLVEASLLEAHGVDGAGAPRYRFHPLLRLTVAPARPALSALSALPTAAMPAMPVSAGAAPGDSGPAAGRPFSVPDTSGPAATVPRTAAGTSVVERVRPRAQERIAVG
>NZ_CP016560.1|WP_003953088.1|170770_171244_+|hypothetical-protein
MAPRKTLGMIVAAAALVAGQFAVGNASAAPAQASPLQQKVDTFLEQHPEARQTSRNTVDFPGGSATIAEPGATVDRTRAPACDNGWLCVQVANGTIYRYYTCQLYQFRGTGDGTFNNNQSSGTVARFYNQNGTQRWTNTAKDTGTASWTPVWSIRPC
>NZ_CP016560.1|WP_003953087.1|171361_171736_+|hypothetical-protein
METNRADDIGGGCGADEEVIPVLRVADAAVAVAWYARLGFVQQWEHRFEPGLPVFTEVARGRVRLFLSEHMGDARPDTLVHLRVTDLDAVAAEFGAEPEEQPWGRETELRDPDGNRLRVGSVDG
>NZ_CP016560.1|WP_003953086.1|171803_172850_-|hypothetical-protein
MRHVRKVSFPAIAVLALAIGLSGSASATPADVGRPDSGPTVLSSPALLDDGTAVDSAADGKRLAEYWTPERMAAALPPHVPDPTTALRAGKAPGPDGEPSAVAPLETPASAAKGSGTPEGPTAEPRIPQSSKTGRVFYRDPIRGTSHACTASMVNSGSRQLVLTAGHCVHTGPVNGRPGAFMTHWTYVPGFRSGQRPYGVFWAKRMTTFASWASHGDVGRDVAFVVTELVNGRKLGDVTGGWGIAFNQPKSMNYMLNGYPSNHGGGNVQQYCGIVVSAQHPSDPSRIYVACAWAEGASGSPFLAAFNQQTLMGYANGVQTQWGCCQYAISPYFDNGVMQLYRSVADVT
>NZ_CP016560.1|WP_003953085.1|173210_173780_-|GNAT-family-N-acetyltransferase
MTTSFWTGTRVRLRGVEPSDWDTFMRFDQHSGHQRSGEAVLPPRSAEGYRGWAKERSTAKPEEDCFQLAIEAVGGPGQAVGIINTYDADPCAGHFRYGISIGAEHQGQGFATEAAVILMRYMFAERRYHKCEVDIYGYNEASLALHRRLGFTEEGRRREHAFLAGAYHDLVAMGLLADEFAELHSLGGL

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016560_1	1.1|161339|42|NZ_CP016560|CRISPRCasFinder	161339-161380	42	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	902323-902364	0	1.0
NZ_CP016560_1	1.1|161339|42|NZ_CP016560|CRISPRCasFinder	161339-161380	42	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	504083-504124	0	1.0
NZ_CP016560_1	1.1|161339|42|NZ_CP016560|CRISPRCasFinder	161339-161380	42	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	161339-161380	0	1.0

1. spacer 1.1|161339|42|NZ_CP016560|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 0, identity: 1.0

acacggacgcggcgacagccggggcaggcgccggagatgagc	CRISPR spacer
acacggacgcggcgacagccggggcaggcgccggagatgagc	Protospacer
******************************************

2. spacer 1.1|161339|42|NZ_CP016560|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 0, identity: 1.0

acacggacgcggcgacagccggggcaggcgccggagatgagc	CRISPR spacer
acacggacgcggcgacagccggggcaggcgccggagatgagc	Protospacer
******************************************

3. spacer 1.1|161339|42|NZ_CP016560|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 0, identity: 1.0

acacggacgcggcgacagccggggcaggcgccggagatgagc	CRISPR spacer
acacggacgcggcgacagccggggcaggcgccggagatgagc	Protospacer
******************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	572470 : 608462	35	Synechococcus_phage(25.0%)	protease,tail,plate	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP016560|572470:608462|DBSCAN-SWA
CTCAATGGCCTTCCGGGAGCGGGGACGGTGGGAGAGACGGTGGCGAAGAGTCAGTGGGGCGAGCAGGGCCAGCGGGGCCAGCAGGATCGGAAGGGAGGACCTCGACCGTGAACGGCAGATGCGCGGGGCGGGCGGCGGCCACCACGGCGTGGAGCCGGTACCGGTCGACGCGCTCCGGCTCCGGCACCGTCAGCCGCACCAGCAGCGAGGCCACCGGATGCCCGGGAAACGGGCCCAGCGGCCGGGCGGACCAGACCGCGCCCCCGCTCTCCACGATCTCCGGACGCGCCCCGAACGCCTGCCGGACGGTGCGCGCCAGCCCCTCGACCGTGCCCCGCAGCCGGTGCAGGGCCACCGCCGACGCGACCGCCCGGCGGCGCGCCTCCAGCGGTTCGGAGCCGTCCAGCTCCGGCCCCACCCAGTCGGCGAGCCAGTCGACGAAGTCCTCCGGCGCCAACGACGGCGTGAAATACGCCTCCAGACAGTCCAGGACGTTGAACAGCGGGGCCAGGACGACATCCAGACCGCTGACGAACCGCTGCGCCAGCTCGTCCTCCGCGTAGACGGCGGGCAGCCGCTCCCCGAGCGGATGCGCGGAGGCCAGCCCCGGCAGGGTGCCGCGCGCCGTACCCGCCGTATCTGTCGTGCCCGCCGTGCGCGCTGTCTCCACCCCCCTCACCGTGCCTCGACGACGCGGACCCGGTGGTCGAACGGGAAGAGCAGGGCCGACGGCACCAGGTCGATGCGGTCGGTCGCGTCCCCCCGCCGCCCCGTCAGCGGATCGGCCGGATGCAACTGCACCTCGTCCACCAGCTCCACCCCCGGCACGCGCTGGAGCGCGGCGAAGATCTCACCCGCCCGCAGCGGGCGCCCGAACGGCCAGCCCTCGCCGTGCGCGCCGCCCGTCAGCGGATCGAGATACGCGTACAGGGCGTCCAGGGCCGCGTCCCGCACCCAGTCGATCCGTACCGCGCGGAACGCGTGCAGGGTCGCCACCACCGTGACGCCCTGGTAGAACGGCGGACCCACGGCCAGCCGGGTGCCGATCGGCCGCCGCTCGTCGAGGAAGGACGTGACCCGCTCCAGCAGCTCGTCCCCGGGCACCAGTTGCTCGAACCGCAGCCGCCGCCCGACGTCGGGCACCGCCTGCGGCACCACCAGGACCCGGACCGCGTTGTCGCCCGCCTCGGCCCGGTCGGCCGCCAGACAGGCGATCCGCGCGGCCTCCGGCGCGGCCCGCCGCGCCAGCTCCTCGTAGTCGCGGGCGGTCACGGCCCGCTCCTGCGCGCGCAGCGCGATCGGCGCCCTGGTCTTGGCCTCCTCGACGGTCTCCCCGTCCACCCCGCCGCGCGCGCCCTCCCGGTTCTCCACCCGGGCGATGTACGGGATGGAGCTGCGCAGCACCCGCAGACTGCCGCGCGCCACGTTCCCGGCCCGGCCGCCGCCGGTGCGGTAGCGGGCCGCCCGGACCGTCGCCCCCTTGCGGGGCACCGCCCCGTACTGCCGCAGCGAGCCGTCCGCCGTCCGCACCCCGGGGCCGAAGCGGATCTCCCCGGTGGCCGCGTCGAGGACGGCGTGCCGGTCGGCGGGTCCGGAGGCCGCGAACTCGTCGACGACCTCCCAGCGGCGCCAGCCCTCGCCCTCCGACACCTCCAGGGTCAGCCCGCCCACGACCGGGGCGTGCGCGAGCCGCAGCCGCTGCCCGGGGACCCCCTCCGACTCCCCGAGGATCTCGTCCCTGACCCGTTCGGAGTGCGCGGCGTCGGTGGTGCCGCCGATGGTGAAGGCGCTCGCGGCCCGCACGGTGGGGGACTCGCTGTAGAACGGCTGCCCGGCCGCCGCCTCGACCACCCGGCAGCGCACCCAGCCCGCGTCCACCCGGGTCTGGCGGGACACCGCGTGCCCGGCGGGCAGATGGAGGATCACCTCGCCGGGCCGGTTGAGCCCGCCGGTGGAGTCCGTGTCGACCTCGCAGCCGCGCCAGCCGTCGGCCGTCCACGCCTCCCACACCAGCGGGGGCTGCCGCGGGTCGACGCCGACACCGTCGACCCGGCTGTCCAGCCGCAGCACCAGCACACACCGGGGCGCCGCTGCCGAGAGCCCGAACAGGACCTGGTCGCCGGGGCGCGGGGGGTCCCCGAACACGGCCGTGTCGGTGCCGCCGAGGACATCCTGCGAGCGGTCCTCGGCGGGGGCGCCCTCGGGCTGCCGCAGGATGTGCGTCAGCGCGCACGGCACGACCGTCAGATCCTCCGTGGTGGAGAAGACCACCGCCTCCTCGGCCTCGGTCCGCAGGGTCGCGACCTCGGTGCCCGTGGGCAGCACCACCGGCTCGGGCTGCGGCGCGGACAGCCAGAACGTGACCGGCGCGCGGGCCGCCGACGGCGGGAAGAGGGTGACGCCCAGCAGATCCAGGAAGGCGAGCCGGTTCTTCTCCGGCACCCGGTTGAGCCGGTAGACGATCTGGTCGGCCATGTGCGCGACCGCCTCGATCAGGGTGACCCCCGGGTCCGAGACGTTGTGGTCGCTCCACTCGGGGCACCGCTGCTGGATATAGCGCTTGGCGTCGTCGACGAACTGCTGGAAGCGGCGGTCGTCGAGATGGGGAGCGGGCAGGGCCATCAGAGTCGTTCGCTTTCGCCGCCGGCCGGATGTCCGCCCGGACCCTCGTACGGGGCCTCGGACGGGATGACATAGAAGGGGAAGACGAGACTGCGGGGGTTGTTGGTGCCCCGGACCGAGTACCGGACGTCGATATGGAGCACGGTCGGATCGTCGGGCGCGGGCGTCACCGTCACATCCCGGACCTCGATCCGCGGCTCCCAGCGGTCCAGCGAGGTCCGCACCTCGTGCTGGATGCGTCCCGCGGTGGCGTCGTTGACCGGCGCGAACACCAGATCGTGCACGGCGCAGCCGAACTCGGGCCGCATGGGCCGCTCCCCCGGCGCGGTCGCCAGGACCAGCCGCATCGACTCCTCGATCTCACGGTCCCGGCGCACCAGCGCGATACCGCCGCCCGGGTCGATCCGCAGCGGGAACGACCATCCCGCGCCGATGAACTGCTCGCTCATCCCCGGTCCCCTCGCACGCGCTCCTCCACCCCTCGATATCGCCGGTGCCGCACCAACGGACCCGGTCTCAGAACGGCACCCCGTTGCGGAGCGTCGCCCCGGTCAGGGTCACGGTCGTGGCCGTGACCGACGCGTTGACGGCGGCCTTCAGCGACACCGAGCCGATCGCGTCGAGCTGCACACTCGCCCCGGCCTTGACGGCGACCTGCCCGACCGCTTCGAGCGAGAGCGAACGCCCCGCCTTCAGCGTGAGATCACCGGCCGACTCCACCCGCACCGCGCGGGTGCCGCTGATGGTCACCGAGCCGTCGCTGCCGATGGTCAGGGCGGTGCTCGCCTCGTCCAGCTCGATCCGCAGCCCGTTCCCCCCGGTCTGGAGGAGAATGCCGCCGCCGCTCCCGGCCGCCGCTCCCGGCCCGCCCGACTCGATCAGCTCGACCGTGTGTCCGCTGCGGGCCGTCAGCGCACGCCAGTTGACCCGGCCGCTGGTCGGATCGACCGGGGGCCGTCCCTTGGGCTCCTCCGGCGGCCGGTCCACCCCGTTGTACAGACCGGCGAGGACATACGGATGGGCCAGCGAGCCCCGGTCGAACGCGCACAGCACCTCGTCGTCGACCTCGGGCAGCAGCAGCCCCCCGCCCCCGACCCCGCCGAACTGCGCCACCCGGGACCAGTCGCTCTCATAGGTGTCCGACAGCCACGGGAACCGCAGCCGCACCCGCCCCAGACCCAGCGGGTCCTTGGTGTTGGTGACGACCGCGAGCGCCACCCCCGGCATCGGCGGCGCGCTCGCCGTCGCGCCCGACGCCAGCCCGTACAGGGAACGGAACTGCCGCCCCGACACCGTCAGCCAGGTGGTGAACGGCTGCCCCGACGCGAACACGTGCCGCACCCCGGTCGCCGTGTACTTGCCCTCGAACGGGGTGCCCGCGCCGTTCACCGACACCGGGACCCCGGGCCGCAGCTCCGGATTGCCCGTGACGGCCACCTCCAACTCGGCGAACGAGCCGGTGATGTCGTCGGCGAGCGCCCGCGCGGCCTGGGTGACCTGCGCCTGGGTCGTGAACGGCGGCCGGGTCGCGGTGGCCTCCGCCTGCCCGAACAACGGGGTGACCTGGCCCGGCGTCAGCCCGGCCGTGATCCCCGGGTTCGCGGTCGCGGGCGCGGGCGCGACCAGGGTCCGCCGCGTCAGCATGTCCCAGCCGCGCACCGACACCCGGTCCACCTGGTCGGCGGCGGTCATCGCGACCCGGCTGTGCAGCGTGTTGGCGCCGAAGTCCAGGACATAGGGGCTCTGCGCGGCCGGGGTGGCGTCCGAGGGCGCGCCCGCCGCCGACGGCAGCGCCGTGAACTCCAGCCGCCCGTCCCCGTCGCACGCCAGCCGGACATCGTTCTCGGCCGCCAGCCCCGACAGGAAGTCCCAGTCGGTGGTCCCCGGCTGGGTGGCCAGCTCGTACACGGTCGTCGTCGCGTCCACCCGCCCCAGCGCGACCCCGCAGCGGGCCGCGACCCGCCGCACGATGTCGGACGCGGTCATCTGCGCGTACCCCACCACGGGACGGTTGCGCAGCAGCCGGTGCGCCGGGTCGTACCCGCGCACCACCAGATGCCGCCCGCTCGCCGGGTCGGCGTCCACCTCCAGGGCGGTCACCTCCCCCGTCAGCATCGGCGGCCCGGCCCGGCCGTCCGTGAACGGGTGGAGCACCACCGGCGCCCCGATCGTCAGCCGGGGGAACTCCGTCGTCAGCAGGCCGTCCTTGTCGCTGAACGTGAGCTGGAACGCGGAGGGCACATTCAGGCTCGCGTCCACCCAGCCCTCGATCAGCAGCAGCGCCAGCGGTTCGGGCAGCTCCGCGCCGCCCACCGACACCTGCAACAGGGTGGTGAAGGTCGTCTCGCTCACGCCCGCCCCCTCCGCTCCGTCGCCCGCCCTTGTGCCTGCCCCTCGTGCCCCTTCACCGTGCTCGCCCCTTCGCCTCGTCCGGGCCGTGCGCCGCCCGTCCGCCCATGCCTGCCGCCCGTCCGCCCGAGGTGGTCTCCCGTTCGCTCGCGGCGGGCAGCAGCAGCTCGGTCCCCGGCCGCAGCCGCATCGGGTCGTCGACGGAGTTCGCCTCGGCGATCAGCCGCCACCGCCCCGCGTCCCCGTACTCCCGCCACGCCAGCGAGGGCAGGGTGTCCCCGGCCACGGTGCGGTGGATCCGGTGTGCCGAGAGCGCCCCCGAGGTCGGGTTCTGCCTCTTGGTCGCGGTGGCGATCTCCGTCAGCGCCAGCGAACAGGTCGCCCGCAGCGGCATCCCGTTCGGACTGAACAGCGTGTACGTGGCGTCCACGCTCGTCACATACGCGGTGAACTGCACCGTCGAGAACGCGCCCCAGGAGAACCGCACCCACGGCGGCGACGGCGCCTTGGCCGCGATGGACTGCGGTGTCACCTCGCAGCACGAGAGCAGCAGGGCCACCTGGTCCTGAACGGTCGCCGCGCCCGGGGTCCCCGACGCGTCGAGGAACACCTCCAGCCGCAGATTGGCCGGGTGGGCGCCGGTGAACTTCGCCGGGGCGCCCCGGGTGTACGCGACGGCCGGCGGTGTGGTCCAGCTCGCCGAGCGGCCCAGCCGGAGCTGCGAGGGGTTGAACCGGAACCGCACCTCGCCGAGCGGGCCACCGGGGTCGCCCGCCAGATCCGTCGGCGGGCTGAGGATGGCGAGGACGGCGCGCGAGAGTCCGGCGGATGGATTGCCGACGGGGGTGGACACGGGTCACGCACCCCCCGCGTCGGTGAAGCCGTGATGGGCGATCTCCAGGGTCTCGGTCGCCACCGCCGGACTCTCCGGATTCAGCGTCGGCCCCGTCCAGCTCACCGGCAGCACCTCCATCAGGCCCCACTGGGCCACGATCGAGCCGTCGGCGCGCAGGGCGGCGATCTGCGCGGTGGGGCGGGTGATTCCGGTGGTGACCGAGGAGATCCAGGTGGCGACCCGTGCCGTGTCGGCGGTCAGCGGACGGGTCAGCCGGATGGTGGAGAAGTTCACCCGGGTGGGCAACTGCCAGACGAACCCGTTGTTCCCGCCCTCCTGGTGCCGCTCGATCTCCACGGTGGAGGACAGCCCCTCACAGCCGTTGAACAGGCCGAGGTTCTGCCCGTCGACGGTGAGGGTGAAGAAGACGGTGGAGCCGGGGTCAGGGGTGGCGGGCATGGTATCCGGGTTCTCCGCGGGTGGGTGGGGACGGATCGGGATCGGGAACGGGGCAGGGGGCGCGGGTCAGCCGTCCCGCAGCCGGCCCACCCGTTCCCGGTCCCCGCGCAACTCGGCCCTGAGCAGCCGGGACAGCGGGGCGACGAGTCGGCGCGCGAGCCGGTCGAGATCCTGGGGGGTGGGGTCGGCGGCGGTGTCGTCGGCGGGGGGCGGTGGTTGCGGCGGCTGGGGTTGCGGTGGCTGCGGTGGCTGCGGTGGGGGAGTGGCGCGTGGCTGGACCACGGGGACGGGTGGTGCGGGCGCCGGTGCCGATGCGGGCGCCGGTACCGCGGATCTCGCGATCGTGATCGGTGCCGGGGGAACGGGAAGGGCGGGGGCGGGTGCGGAGAGGGCGGCGGGCCGTGGCGCGGGGCCGGGGCCGAGAGGGACCGGTGCCGCGGTGGTGCTCCTCCGGTCACCCGGCTCGATCCGCCGCAGCGGTGCCGGACCGCCACCGCCAGGGGGAGGGGGCGCCGGTGCCGTCGGTGGTGTCGGACCGCTTCCGTGGGAGACCGTCAACGGGCGGGACGAGGCCAGCGGCCCGCCGGAGGGGGCGCGTTGAAGGGCGGGGAGGGGGACCTGCACACGGGGGAGGGGCACCGGGTCCGGTGCGGGGGGTGGGGCTGCCGGTGCCGGTGATGATGGCGGCGGCGGTGGTGGTGATGGTGGAGCGGTGGTCCGTTGCACGGGCGCGCCGGGCGACGGCGCCGGACCTGCGGAGAGGGGCGCGCCGATGGAGGACCGTCGCCGCGAACCGCCGGGCCCGGGGCCCTCGGGCGCCCGGTCCCGGGTGGTCCGCCTCACCACGGGCCGCCGCTGGACGAACGGTCCGCGTTCCTCGGGGGCAGGGCTCCCCGCGCCGGTGGGGGAGACCGGCGCGGGGAGGGCGGGCGATGCCTCCGGCGCCGGAGGCATCGCCAGGGGCTTCCCCACGGCGGCGATCCGCCGCGAGGGCACCACAGGCCGCGGAGACACCGTCAACGGCGCACCCCCCACCACCGCCCGCACCACCGGCGCCGGAGCGCCGCTTCCACCCCTGACGGCCGGACCGGACACCCCGGTGCCCTCGACGGCGGGTGCTCGCTGAACGGCCGGGGCCGGGGTCGGGGCCGAGGCCGGGGTCGGGGCTGCGGTGCGTCGGTTGTCGGCGGGGCGGGGCGCGGCTGTTGTGCCGTTCGCGGTCCGCTGCACGCCGGGGGAGCGTGGAGCGGGCTGCTGGTGCGGTGGTTCAGGTTCGGGGGTGTGCCTCGGGGAGGTGTCTCCGCCTCCGGCGGGGGCTCGTTGAACGGTGCGTTCGGCAGCGGTGGGCGGGGCCGTGGTGTCGTTGGCGGGCGTGGTCCGTGGGGCGGGTGGTGCGTGCTCGTCCCCGGCGGGGGCTCGTTGGATGCTGGGTGTGGGTGTGGGTGGGGGTGTGGTCCGGAGTGCGGGCTGCTGTTGTGGTCCGGCGCCGGGCGCGGGCGAGGCGTCCTCGCTCCTGGCGGGGGCTCCGGTGGTGGGCGCGGGTGGGGTGTGCCCGGCCGGAGCGGCGGCTCGTTGAACGGTGGTGTCGACGGCGGGCGTGCGTGGGGTGTCCTCGCCTCTGGCGGGGCGTTGGGCTGTGGTGGCGGGCTGCTGTTGCCGTGTTTCGGTGATGTGCGCGGGGGCGGCGCGTTCGTTCGGGGCGATGGCTCGTCGGACGGTGGTGTCGGCGGTGGGCCGGTCGTCGGCCGGGGCGTCGTTCGTGGCTGTGGCCTCGGTGGCGCGCTGCTGTCGTGGTCCGGCGCCGGGTGCCCGTGGGGTGTCTTCGCTCCTGGCGGGGGCCCGTTGAACGGTGCTGTCGGCCGTGGGCCGGTCGCCGGTCGGGGCGGGGCCGGGGGTGCTGGTGATGTCCCCCGGTGCCGGGCGCGGACCGGGAGCCGGGGTCCGGGCCCGTTGGACGGCGGGGGCATCGGCGGACGACGACTCGGTTCGCGGGGATGCGTTGACGGGCGCGGAAGCGGCAACGGGGTTCCGGGGCACAGGCTCCGCGCCCCGGACGCCCCGGACGCCCCGGCCTTGCCCGGTCGACGTACGGGCCCCCTCGGCCGGACGCCCTCCGGGGCCGTCGATCCGGCCGGGTCCGGGCACGGGGCCGCTACCGCCGGGCACGGAGCGCTGTACGTCCTGCCTCCTGCCGTCGCGCGGGTCCGGCACGGAACCGCCGTCCATGGGCGCGCCGGTGGCCGCCCGGCCTTCGGTACGGACCGCCCGGGTCCGCTGTGCGGGGGCCACGGGGCTACTGATGCCGGGGTCGGCGCCGATGCCTGTCGCCCCACCGCCTTCTGAGAGGGCACGGGGGAGGGCGGGGGCTGGGGCGCTGCTGGCAGGGGTTCGTTGTACGGCGGGTCGGGGTGCCTGTGGGGTGGTCGGGGTGGCCGACGGTGTGCTGGCACTGGGTGCGCGGCCGGGGGCGGAGTCGGTGACGGGGCTGTCGACGGTCGGTTCGCTGCCTGCACGGGTGAGGGTGGGGGCGTCGTCGTTCACGGCGGGGGCTCGCTGCACGGCGGGCCCGAGACTCTCCGGAGTGGTCGCGGGGACCGGAGCGGGTGACGGCGCGCCGATATGGGGTGTGCGGCTGGAGGCGGAGTCGGTGACGGGGCTGTCGACGGTCTGTGCCCCGCCGGTGTTGGCGGTGGCGGCTGTGTCGTTCATGGCGGGGGTTCGTTGTACGGCGGGCTGGGGTGTCTGTGGGGTGGCCGACGGTGTGCCGGCACTGGGTGTGCGGCTGGAGGCGGGATTGGTTCCGGGGCTGTCGACGGTCTGTTCCCGGCCGGTGGTGGTGGGGGCTGTGTCGTTCACGGTGGGGGTTCGTTGTACGGCGGGCTGGGGTGTTTCCGGGGTGGTTGGGGTGCCTGGAGCGGTTGACGGTGTGCTGGCACTGGGTGTGCGGCTGGAAGCGGAATCGGTACCCCGGTTGACGACGGTCTGTTCCCGGCCGGTGTTGGTGAGGGTGGCGGGGGTTCGTTGTACGGCGGGTCGGGGTGCCTGTGGGGTGGCCGGGGGGCCCGAGGCGGGTGACGGCGCGCCGCCACCGGGCGTATGGCCGGATGCGGAGTCGGTACCCGGGCCGACGACGGTCCGCCCTCCGCCCGAGGCGTCGGCGGCGTCGGCGGCGTTCACCGCTGTCGGCCGTGCACCCGCGTCCGCGTCCGTACCCGCGCCCGTACCCGTCCGATCCGATCCCGCTGGGGAGCCGGACCGGCCGGGACCGGCGGTCCGCCCGCCGCCGTCCGGGGTGGAACGCTGCACCGGCGTGGTGGCCTCGGCCCCCGGGGTGGGCACGGACGGGCGCGGGGCCGCCGGGACGCGTCCCCCGCCCTCTCGGCCTCCGCCGCCCCGCGCTTCCCGCGCTTCCCGTGGTGGTGCTGAGCCTCCGGAACGGGTCGACCGGCCCGGGTCGCCGACCGTGGCCCGCCGCCCCGTTGTGACGTCTTCCCCACCCGGCCCGGACGGCCTGTCCGCGGTGGACGCGGCGGACCGCCGCTGCACAGCGTCGACCGGCCCCGGCCCCGGCCCCGTTCCCGTCCCCACCGCCTCCGCCGCCCTCGTTCCCCGCACCGTTCCGGACTGCGGAGTCCCGGATTCCGGCGCCTCCGGCAGATCCGGGACGACACGCGGCAGATCCGGGCCACCAGCGGCCGGGCCACCAGGAACGGCACGCGGCGAATCCGGAGCACGCGGCGCATCCGGAGTGCGCGGCCCCTCCAGGCCCCCCGGCGCATCGGACCCGCCGCCTCCGCGCCGCGCCACGGGCAGCCGCTGAACGGGCAGGGACCCCCCGGGGGAGCCCCCCACCGGGGGCCCGGCGACCGGGGTGAGGACATCGCGGACGACACCGTGGGGCGCGTCGCCGTCGACGGCGTGGCCGACGCCCCCGCCGACGAAGGAGTGGTGCCGATGGGTGGCCAGCCGATCGGCGAAACCGAGGTCCGCGGTCAGCCGGGGTGCGCCCAGCGCGCGCTGGATGGGGGCGGTGACCGTCCAGCCCGCCTCAGGACCGCCCCCGACCGGAGCAGCGGGCTCCGGAGCGGCGGAGGCCACGTCGGAGGGCATGGCGGAGGTCACGGCGGAGGACTCCGGGGCGGCGGAAGCGTCCGGGGCGCCCCCGTCACCCGTCCCCTGCCCGCCGCCCCGCAGCCGAGCCAACCAGCCCATCCCTCGTCACCCCTGCCCTTCGTCCTGCCCCACCAGGGCGGCCACCCGCCGTACGTACGCCCGCCGGTCGGCGTGCTCCAGATCGAGGATCGAGTCCATCCCCCAGTGCAGGTGGAAGGCCAGGTACGCGGTTTCCTCCTCGATCCGGTCGGCCGCGTACGTCACGATTCCCCCAGGCGGCTCCCGGCCAGCTCCACCTCGAACGACTCCTCGCAGTGCGGGCACGCCACGGCCGCCCGGGTGTGGCCCTCGGCGTTGATCTGCCGATAGAAGTCCTGGAGGAAGGCGAGGTCGGAGGCGAACATCTGCTCCACCGTGCCGTCGTGGACGGCGGGCAGCGTGCCGAGCCGGGTGATGACCCGGCCGAGCAGGACCACCGACAGATACGCGGGGTTCTCGCGCACCCGTATGTCCCGCAGCGGCACCAGCTCGTCGCGGGCCGTGGCCAGACGCATGGCCCCGTGCCGGTGGACCGTGCCGCTCTCGTCGAGGTAGCCGCGCGGCAGCTCGAACGCGAACTCGGTCCGCAGGGGCGCGGACCGCCCGCCCGCCCCACCGCCACCGGTGGCCTCGTGGACACCGGTGACCCCACCGGTCCCGGGAAACCCCGGTGCCCCGGCGGACCCCGGTGCCCCGGGCGCTTCCCGTCGCATCAGCCGAGCGTCAGTTCTTCGAAGGTGATGGTGATCGTCTCGGTCAGGGCCGAGGTGTCACCCGCCTTCGCCGAGCTGACCTCCACCTTGCTGCACCACGCGTTGCTGAGGTTGTAGCGCTTGACCGGCCGCCGCTCGTAGTCCATGAAGATGATGCTGGCGTTCTTGCGGGCCGAGCCCATGTTCCCCTCGATGGACTCCCTGATCCACTGGGTGAACACCGCCGACTGGGTCGCGCCGCGGACCACCGTGCACTCCCCGGCCTTGCGGGCTCCGGGCAGCTTCTTCACCATCGGCTGCCCGTTCGCGGACACCTGCTTGTACTCGATGACGTCCTGATCCATCGTGAGGCTGCTGACCTCCTGGAGGAACTCGACCATGACACCGTCGATCTGGATGCCGAAATTATGTGCGACGAGGGCATCGCCGGGCTGAAGAGACATAGCGGATCACTCCTGTGCTGAACGGGACGAGGGGGACGGGAAGCGGACCGGCTGCGCGGACGGAAGCGCGGAGCGCGGAGGGGGGGGTCACTCCTCCAGTTCGGCGCCGCCCCCGGAGATCTGCGCCATCCGGAAGACCACGAACTCGGCGGGCTTGACCGGCGCGATACCGATCTCGCAGACCACCCGGCCCAGGTCCACGGACTCCGGGGGGTTGGTCTCCTCGTCGCACTTCACATAGAACGCGTCCTCGGGCCGCTGCCCGAACAGCGCGCCCGAACGCCACTCCGTGACCAGGAAGGCCGAGATATTGCGCCGGATGCGCGCCCACAGCGCCTGGTCGTTGGGCTCGAAGACCACCCACTGGGTGCCGACGAGGATCGACTCCTCCAGATAGTTGAAGTACCGGCGCACATTGAGGTACCGCCAGGCCGCGTCGGAGCTGAGGGTCCGCGCCCCCCACACCCGGACGCCCCGCCCCGGGAAGGCCCGGATGCAGTTGATCCCCGTCGGGTTGAGGAGGTCCTGCTCCCCCCGGGTGATCTGGAGGTCCAGGTCGACCGCGCCGCGCACCACCTCGTTGGCAGGTGCCTTGTGCACACCGCGCTCGAAGTCGTTCCGGGCCCACACACCGGCCATATGGCCCGACGGCGGCACACTGCGGGTCTGCCCGGTCGACGGATCGAAGATCTTGACCCAGGGGTAGTAGACGGCCGCGTACCGCGAGTCGTACCCCGCCGTCTCCATCCGCCAGGCGCGGACCTGCTGGGCGTTCAGACCCGGCGGCGTGTCCAGGACGGCCATCCGGTCGCCCATCAGCTCACAGTGCGCGATCAGACCGAGCTGGACGGCTTTGACCTGCTCCAGATCGATCAGGCCCCGCTGATGGGCGGACATCAGATCCGGCACGGCGACCATGCTCACCGCGTCGATCGCCTCCAGACCGCCGAAGCCGGTGCGGTCGGCGGAGTCCCCGATGAACCGGGTCGGCCCGAGCCCGCCTCCCGCCGCGTCCGGAACCACCGGAGCGGCCCCACCGGCGGTCCCCGGCGCGGGGGCCGGCGGCTCCAGGGCGACGGTCTGCGGCTCCGGCTTGGCGAGCTGGCCGCCCGTCCGCGCCTCCTCGATCACGATCGTCCGGGAACGCTGCCGGACCTGCGTGACCACGTAGTTCTTCGCGGACTTGCGATGGCTGACGTCGAAGGACTCCACGACGGTGTCGCCGTCCTTGACGACGAGGGTGAACCGGTCGGCGTTCCCCTCACCCTCCGGGTGCGCCACCTCGACGGTGAGACCGCCGCCGTCCGCACCGGCCGCGACGGCCGACACGGTGAACGGCCCCAGCGCCGCCGGCCGCCCCGGCGGCAACTGCGCGGGCGCGTCCGCCACGGCCCCCGCTCCCGGGGCGGCGGCCGGGTAGGTGCCGTCGGACGTGCCGCCGATCCGGATCACGTACGCGGCGCTGCCACCGTTGTTGAAGAAGCCGTAGACGGCCTGCGCCAGGTAGTACCCGTCCGTGAACTCGCCGAACTCGGCCACGTACTGGGACCAGTTGGTCACCAGCGTCGGCTCGTTCAGCACACCGGTGGGTGCCAGGCCGACGAAGGCAGCCACCGACGTCCCGATGCCCTCGATGGGCCGGGAGCCGCTGGCGACCTCTTCGACATAGACACCGGGGGACAGGTAGTTGGGCATGAGGCGCTCTCCCGGAACGAATGAGGGGGATGCATGACGGAACGCATGCATGAACGAGAGGAATGCGGGGGATGGCGAGAGGACGAGCAGACGACAAGCGGAGTGACAACGGGCCGCGCCGGACGCCTGGGTGCACAGGACGGACCGGCGACACGGGGTCCGGCCCCGACCCTGACCCATCGAGGGCGCCCGGGGCAGGGATGCGCGTACCTCCGTCGGGGCAACCACGGATGCCCGAAAGGACCTGCGGGGCCCGGCCGGACCCGTTCCGCCCCATCCCCGCCCGGGATCTCCCGGGCCGGGTCGGACCCGGCCGGACGCCCACCGATACCGTTTCCCCGCACACGCCGACGACCGACCGAAAGGGCAAGGTGACGGCCATGCCGGGCAGCGGCGAGGCCCCTGGCGGACTGCGGTTCCGCCTGCTCGGACCCCTCCAGGGCGAACAGAACGGCCGGCACCTGCCGCTCGGCCCGCCCCAGCAGCGCGCCTTCCTCGCCGTCCTGCTGCTGCGCGTGGACCGGCCCGTCTCCACCGCCGAACTCATCGACGCCCTCTGGGGCGAACGCCTCCCCGACCGCGCCGTCGGCACCCTCCGCACCTATGTCTCCCGGCTCCGCCGCCTCCTCGAACCGGAGCGGCCCGCCCGCTCGGCCGCCACCGTGCTCGTCTCCACCGACGACGGCTATCTGCTCCGCGTGCCCCCCGGGGCCGTCGACACCGTCGAGTTCGAACGCCGCACCTCCGCCGCCGGGCGGCTCCGGGCGGCCGGGGACACCGAAAGCGCCCACGGGGAACTCGACGCCGCCCTCGAGCTGTGGTCCGGCACACCCCTCACCGGGCTCCCCGGACCGCACGCCGCCCGCCAGCGCGACCGGCTCACCGAACTCTGGCTCACCGCTCGCGAGGACCACTTCCACTGCTCCCTCGCGCTGGAACGGCACACCGCGACCATCCCCCCGCTGCGGGCCTTCGCCGCCGAACACCCCCTGCGCGAACGGACGCAGGCCCTCCTGATGCAGGCCCTGCACCGGGACGGCCGACAGGCCGAGGCCCTCGGCGTGTACGAGGAGACCTGCCGCGCCCTCGCCGGGGAACTCGGGGTCGGACCCGGCCGCGAACTCTCCGCCCTGCACACCCGGCTGCGCACCGCCGCCCCCGGCGAACTCCCCGAGGCCCGCGCCACCGTGGTCCGCGTCCGGGTCCCCCGCTCCCCGGCGGCCCCGGGCGACACCCTCGAACGGGTCCTCGCCGAGACCCGGGCCGCGCTCGTCCGCTTCCGCCCCGACCTCGTCCTCACCGCGCCGCGCCCCGGCCCGCCCCCTCCGTCGGCCGCGCCCCCGCCCCTTCCCGAACTGTCCCTGCCAGGGCTGACCGAGGACTTCCAGCAGCGGATCGCCGACGCCGTCGCCGCGGCGCTCTCCGCCCTCACCGACACCGACGCCGACATCGGAACCGAGAACGGCACGGGCACCGGCACAGGGACCGGCACGGGCACCGGGACCGACAACGGCACGGGACGGACGGCGAACGGGCGGGTCCCGGCCGCCCTCGACGCCACCGGGGAGCTGCTGACGACCTGGTCCCGTCTCGTCCAGGGAACCGCCGACTGCCACCGGCCCATCGCCCCGGCCCACCGGCTCCTCGCCGCCGCCCGCCGCCACGGCGACCCCTCCGCCGCGGGCCGGGCCCTGCACATCCTCGCCACCGCGCCCCCCGTGGGCATCGACGACCTCGGCCGGAACATCGACCGGCTGCGCCGCGCCCTGCGGCACTCGACGAGCCCCGGCGACACCCCGGCCTCGGCCGAGGGCGCCCTCGACCTCGCCCTTCTCCTCGTCCTCGTCGGCCGCCCCCGGGAGGCCCTGCCCTGGAGCGAGCGCGCCCGGGACCGGTACGCCGACCTCGACGCCCCCCACCACCGGGCGCGCGCCCTCGCCCTGACCGCCCGCGCGCACGCCCTGCGCGGCGACGCCGAGGCCGCAGGGCGGGCGGGCGACCAGGCCCTCGACGAGGCCCGCGCCCTCGCCGACCCGCACACCCTGGGCTCCGTCCTGCACCATGTCGGCTGCGCCCGGCTCGCCCTCGGCGACCACGGCCGGGCCGTCGCCCATCTGCGCGAGGCCCGGTACCACCACCGGCGCACCGGCCAGCCGCGCTGGGAGGCCCACGCCTGGTCCCGGCTCGCGGAGGGCGCCCTCGCCCAGCGGCGCCCCGAGGAGGCGGCGGCCTGCGCCACCCAGGCGCTCGCCCTCGAACGGACCGTCAGGGACCCGATCTGCCGGGGCCTGGCCCTCGCCGCCCGCAGACAGGCCCTCCACATCCTCGACACCCACCCCCCGGGAACCCCCCTGGACCTCCCCGCCCCACCCCTGTGACCACGCCCCCGAAGGCCCCCGCCACCACCGTGCCCGCGCGCCCCGCCGCGCCTGCCCGCCGCGCGGACGGCACCCGGCGACGACATCCCGGCTGCTACCGTGCCATCCGGCCGAAAACCGTCCCCGAGCGGTCGTAGCCGGTGCGCGAAGCCGGTGCCGGCGGCCGAAGCGGCCGAACGCTCCGGCGCCGACCCGCTCCACTCCGTCCCGCCCCGGCACGGTCCGGTCCGGTCCGGTCCGGGACGACGCCCGCCGCCGTCGCCCGGGAGTGCCCCCGGGGACGCGGCCCCGGCCCCGAGGGCAGCCGGGGCGGGCCGAAAGGGCAGCCGGGCAGGGGGAAACGCGCGGTCGGGCAGAGGGGCCGACCGGACGGGCAAGGGCAACCGGCCCCGGAGGCAGTCGGCGCTGCCCCCGGCGCGGCCCTTCCGGGCTGGGGCCGGGCGCGCCCGCTTCCTACCGTTCCCGCATGACCCTCTGGACGTCTCTGGACCCCCCTGCCCGCACCGTCGAACCGGGCGGGCACGCCACCGCGCGGCTGCGGCTGCGCAACACCGGAGACACGGTCGAGGAGTACCGGATCTCCCTCGTCGGCGCCCCCGCCGGATGGGCCCGCGCGGAGCCCGACGTGCTCCGGCTGTACCCGGGGACGGAGGGCACGGCCGAGATCTCGTTCGCCCCGCCCCGTACCTCCGACGCACCCGCGGGGCCCGCCCCGTACGGCATCCGTGTCGAACCACGTGACCAGCCCGAACTGCGGACGGTGGTCGAAGGACAGGTCACCGTCACCCCGTTCGCGCAGATCAAGGCCGAACTGCTGCCGCCGAACCTGATCGGCCGGTTCCGGGGCCGGGCCCGGATCGCCGTCGACAACCTCGGCAACACCCCGCTGACGGCCTCGCTCACGGTCCGCGACGAGAGCAACGGCCTCACCTTCGACCTCCAGCCGGGCGCGGTCCAGATCGGGCCCGGCCGCGCCGCCTTCGCCGACCTCGTGGTCCGGCCCCAGGAGATCCGCTGGACCGGCACCGCGCAGGAACACCGGCTGACCCTCTCGGTCCGCCGCTCCGGCGACGAGCACGGCCAGGATCTGAACGGGGTCTTCGACCAGCGCCCCGTCCTGCCCCCGTGGCTGGTCGTCGTCGGCGGGCTGCTGGTCGCCGCCTGTGTGGCCTTCGTCGCCATCTGGCTGGCCTTCACCCCCACCTTCGGCAGCTCCGCGGGCGAGACCCGGGCCGCCGGCCGTCAGCCCCTCCCCCAGGGGGAGAAGAACGCTCTTCCGCCCGCGCCGGACGCCCCACCGGGGGAGCCGCTCAAGGAACGGCCCTCCGGCTCGGACGGCGGTTCCGACCCAGGCCCCGGTCCCGGCTCCGGCCCCGACCGCGGGGCCCCCGCCGGGGGAGGAGACCCCGGCGCCGGGTCGCCGGACCGGGGCGGCGCCCCCGCGGGACCGGACCGCCGTCCCGCCGCCGGAGGGGACAAGGGCCCCTCCACACCGGATCGGCGGCCCGCCCCGAGAACCACGAAGCCCCAACCCGCGAAGCCCAGACCCACACCGCCCAGGCCCGCGCCCGTCGGGCCGCCGTGGCGGAAGGGCTACCAGTCGGACGACATCGTGCTCTTCGCGCAGCACCGGCTGTCCACGCTCGGCAGCAGGAACCCCTGCAACCTCGCGAAGAACTTCACCCCCGGGGTGATCGACGACCGCACCGACCGCTCCCTGCGCTGCTATCAGCGGGCGGTGATGGAGCATCCCAAGCTCACCCGGCAGCTCACCCGCACGGACCCCTACGGAACCCTGGGCCGGGCCACGCTCGCGTCGATGTGGACCCAGTCCATCAAGCCGTCCGACGTCACCCTCGGGTCGGAGAACATCGAGGTGACGAAGCTCAACGCCGCCCTGTGGTGGGCCACCCAGGCCGAGATCTCCGACGGCGACCTCCACCGCGACCGCGCCTACGCCCGGCTGGGCATCGCCTACTTCTCCGGCAAGGGGAGAGCGGTCACCCCGTTCAACAAGAGCGTGGAACACATGGTCCGCGTCTATCAGCAGCGGGTCGGCCTGAAGGCCACCGGCCAGGTGAACTGGGACACCCTCTTCGCCCTCCTCGGGGGCTCGGTCCACCGCCCCGGCGTCCCGGGCCGCTGACCGGCCCACCGGCCCCGTGCCACCGGCCCCGGTCGCGGTCACCCGCGCCCGGGGCCGACACGTCCCCCGGCACCGGCACCGGTACCGCTACGGGCCCCACCCCGTCCCCGGCACCAGCCGCCCCGACTTCAGATACTCCCGCCGCGCCCCGGCCCGTACATCGTCCGAGGTCACCGCCCCGCCCCGGGCAGCCGCCAGATACGCGGCGGTGGCCGCGCCCGCCCGGATGGACCCGCCCGCCAGCTCGAACTCCTTGGCGAACGCCGCGAGGCCGTCGTCGAGCCCCGGCTCCCGGGGCGCCCCCGCCAGCGAGGACCGCCACAGCCGCAGCCGCGCCTCGGGGTCCGGGAAGGGGAAGTCGACCACCATGTCGAGCCGCCGGGTGAACGCCTCGTCGATGTTCGCCCGCAGATTGGTGGTGAGGATCGCGATCCCGTCGAAGGACTCCAGCCGCTGGAGCAGGAACGCGCTCTCCAGATTGGCGTACCGGTCGTGCGAACTCCGCACCTCGGACCGTTTGCCGAACACCGCGTCGGCCTCGTCGAAGAGCAGCACCACATCCGTCCGGTCGATCTCGGCGAAGATCCGCTCCAGGTTCTTCTCGGTCTCGCCCACATACTTGTCGACCACCGAGGACAGGTCGATCACATAGAGATCCAGGCCGAGTTCCCCGGCCACCACCTCGGCGGCGAGGGTCTTGCCGGTGCCCGAGTCCCCGGCGAACAGGGCCACCACACCCCGCCCCCGGCCCCCGCCGGTCCGCAGCCGCCACTCGCCGAGCACCCGGTCGCGGTGGCGGGCCCGCCCCACCAGCTCGCCCAGCATCCCCAGGGGCTCCCCGGGCAGCACGAGATCGGTGAAGCCGACGGCGGGCCGGACGCACCGCGCGAACCGGCCCAGCAGCGGGGCCGACAGCAGCCGGGCACTGCGCCGGACATGCCCGGGACCCACCGGCACCCCCTCGAAATCGGCCAGCGTCACCGCCGCCCGCGCCGCGCGCCGCACCCGCTCCCCGCCCGCCCGGTAGGCGCCGACCGCCGTCGCCAGGTCCCCCGCGTAGTCGGGCAGCTCCGCACGCCAGACGCTCAACGGGTCGGCCCCCGCCGACACGTCCTCCACCGGAATGACGACGGAACGGGGCGCCCAGCCCGGGTCGTACGCCACCGGCCCGGCCAGCACGACCGTCACGTCCTGCTGCTCGGTCAACGTCCGTACCAGGGGGCCGGGCTCCTTCGGCAGCGGCTCGACGACCAGGGCCGTCCCCGCGCCCCGCAGCCGTGCTTCGCGCACCAGCGCCCGGGCCACCCCCGCGTCCTTGTCGTCGCCGCGGGGCCGGAACCGCAGCACGGACCGGCCCGCCGCGCGCAGCGCCCCCGTCACCGCGTCGGCTCCGTCGCCGTCGCCCTTGTCCCGCAGATGGACGCGGACCGGACGCCTGTACGCGGCGATCCTGGCCGCGGTCTCGTGCCCCGTGTCCCGTTCCGTGTCCTGTCCCGTGTCCTGTCCTGTGTCCTGTTTCGCGTTCTGCCCATCGGTACCGGACGGGCTGCTCCCGGCCGTGGCGGGCAGCCACTCGACTCCGGCGTCCGACAGCAGCGCGTCCAGCCGCTCGTCCCCGAGCAGATGGGCGATCACCCGCTCCGGTACCCGTACGGCCCGCCCCGGAAGGGGGCGTTCCTCGTCCTCCAGGGTCAGCAGCCCCCCGGCGATCAGGGGCGCGTCCGGGTGGAACCGGGCCCGTGCCACCGGCTCCCAGGGGCCCGTGCCCAGCAGCTCCAGGGCGAGCGAGACGGTGGCCCGGCGGCGGCCCACATCGTCGTTGAGATACCCGTACAGAGCCTCGAACCGGCCGTCCACGTCCGGGGCGAGCCCGGCGAGCAGAATCCATCCGTCGAAGCCGGACAGGCCGAACCGGTCCACCAGCGATCCGAGCCGCGCCCCGAGCGGGGGGAGCCCGGGCACCGGCCCGGCACCCGAGCCGACGGGGACGGCGGCCAGTTCGACCGCGCTCTCGTGCGTCATGTACATCCCGCGCAGGGGGTCGTGCGCCGTCGGGTCCGCCGCCGAACGGGCCGCGACCCGCTCGGCCACCGCCCGGCGCAGCTCTTCCAGTACGGTCAGCAGCTCACCGGCGGCGCCGGTGGCCGGTCCGCCGGCCGCCGACGGCCCCCGCGGGGCGGCTGCGACGGTGTCCCTGTCCGGCCCGGTCATGACTCCGTCCCCCGCTCCGGCTTCCGCTTCGCCCCCGGGCCCGGCTCCGCGGCCCCTGTCTCCTCGGCTGTTCCGGCGGTTGCCGCCGCCCCCGCGCGTTCCGTTCCATTCCCCGGCCGGGTCCGTGCCTCGGCCCGGATCACGCGCGGACGGCCCCGGGCGGCGTCGGGGCCCTGCCGGTCCCGCACCGTGACCTCGATCTCCGTCACCGGCGGGCCGACCTCCCAGACGGGCGTGACCGGGAACGGAGTGGTGATCACCACGTCGAGCGAGGGCTTCAGCTCCCCGCCCAGCGCCGACCAGATATCCGCAAGGGAGCGCGACTCGGCAGGCGGCACGGCCACCGTCAACGGGATCGGAATCCGGTACTCCGACAGCGCCGCCGGGACCGATCCCGCGGGCAGGGTCTCGTGCGGCAGCAGCGTGGCGAGGACCCCCGACAGCAGCCGGTGCTCGTCCTCCGGCCGGGTGGTCCACGCCGTCACCAGGTACGACAGCCGGTACCACCGCATCGGCTGCCGCTGGCGCACCACCACGCCCCGCTCGTCCCGCTCGGCGCGGGCTCCCCGTTCGCGCCGGGCCACGTCCTCGCGGATGTCGTACAGATAGGCGTTGACCGTCGGGGCGTTCCGGCGCGCGGCCCAGTCCCGGGTCGGCGCGTCGAAGGCGACCTCCCCGGTCCCCTCGGGCAGGGCCCCGCCCCGCAACAGGCGCCGCAGCGCCTCGTCCATCTCGTGGATCATCGTCAGGAATACGTCCTTCACTCGGTGAGGGGACCGCCGGGGCGGCCGTCGGGCGCGGTGGCGCGGGCACGGAGGCGGCAAAGACAGCAAAGACGGGAGCGGCGGGAGCGGCGGGAGAGGCGGCGGGGATGGCGGAGGGCCGGTCAGATATAGCCCTCGCGCAGGGCGAAGGCCACGGCGTGCGCCCGGTTGGAGAGCTGGAGCCGGGTCATCACCCCGTGCAGGATGTTCTTGATGGTCCGCTCGGAGTAGGCGAGCTTCTGCGAGATCTGCCGGGTGTCGAGCCCGTCGGCGATCAGCCGCAGGACGTCGACCTCCCGCGGGGCCATCCCGAGCAGCGGTACCGAACCCGTGCCGCTCTCCTCACTGCCGCACCGCCTCAGCCGTCCCACCTGTGTCAGCAGTTGGTTGAGCAGATCGATGGGGAGATCGCTCTCGCCCCGGGCCGCGCGGTGCACGGCCTTCAACAGCCGGGCCTCGGTGGCCTCATGACGCCACAGGATCGCCCGTACCCCGCATTCGACGACGGTCAGCAGATCGTCCTCACGCAGCTCGCGGGCGACCAGGACGACCGGTCGCTCCAGACCGCGCGAGATCCGCCGCAGCTCGGCGGCGACCACCTCGTCGAGCCGGTCGACCACCATCACGACCACCCCCGCGCAGCCCTCGGCCCCGCTCTCCTCGACCACCTCGACGGAGCCCTGGTGGCGCAGCAGGCTTCTGACCCCGGCCCGCCCGATCGGATCGGCCGCCTGGACACCCACCCGTATCCGCTCCGAAGGCAACTGGCCCACGTATCCGTCCTCTCTCGCTCGGCAGGTTGTTCATCCGGCCGCCACCCGACCGGCGTCAGAGCTTCACCTGGGCGAATCAACAGCCAGTCAACACGCCTTAACACTGGCCGAATCCCATCGCCGCGTCCGTCGCTTCCGCCCCGTCCCCTGTCTCCCGAAGGCCCCGGGAGTACCCCGCGTACCGGGCACTCGGCGCGGCCGTGCGCTGCCCTTCCGGTCGGGGTGCTCTGCCCTCCGGTACCTCGCGGCGGGAAGCGCCCGTCCGTTACACAGGACGTGCCGGACGCACAGGGCGGTTCGGAGCACAGGACGTGCCGGAATCCCGTGTCGGAAGAGGTCCCGCGTGTACAGCCACGAGAACGCCAGGACCAGTGGTCCCACGGCGGCCGAAAGGCCCGAGCGGAAGGCGCAGCGAGGGCTTCTCGCCTGGCAGGGAACCGCGGGGAACGCCGCCGTCGTCCAGATGCTCCGCCGGGCGGGCCACCCCTGGGCGCAGGGCGGCGGGGACGGCGGCCACGCCCAGGGCGACCGGGCCCCGGACCAGGAACAGCACCGGCACGGCCCCGGCTGCGACCACCGGCGGACCGGCCCGGCGGCACCGCCCGTACAGCGCTCGACGGCGGAGCCCGTACAGCGTTCCGCCGTCCACGATGTGCTCCGCACCCCCGGACAGCCGCTGGACACCACCACCCGCACCGAGATGGAGGCCCGCCTCGGCGCGGACTTCTCCGATGTCCGCGTCCACCGGGACACCGCAGCGCAGGCGTCCGCGGCCGAGGTCAACGCCCGTGCCTACACCTCCGGCAGCCATGTGGTCCTGGGCGGCGGCGGTACCGACAAACACACCCTCGCCCATGAGCTGACCCATGTGATCCAGCAGCGGCAGGGCCCCGTCGCCGGAACGGAGAACGGGTCCGGGCTACGGGTGTCGGACCCCTCGGACCGCTTCGAGCGCGAGGCGGAGGCGAACGCGGCCCGGGTGATGCGCGGGCCCGTTCCCGAACGGGACGGCCAAGGGGCCGCACAGCCATGAGAAGATCCCCGTTCACCTCCCTGAACAGGGCGGGGAACGTGAGGGGGGAACCGGAACGTGGTCATGTTGGCCGAGAGTTGGTCGGACCCTTCCGTGGTGGTGTCCATCGCGGCACTGCTGGCGACGGTGGCGGTCGGCGTCGTGGCGGCGGTGGTGGCGCGGCGGGCCTCGTTCGCCAAGCGGCGGCTGACCCACGATCTGGCACCCCCGGCGAGACTTCTGCCCCCGGGGTCCGGCGACCGGCTCGTGGTGACCTGTGACGGCAGCGCCCTCCGCGATCCCCACATCGCGGAGGTGCACCTCGCCAACACGGGACGCCGGGACATCGCCAGTGGTCTCTTCGACGGTGCCCGGCCGATCAGGTTCGAGCTGAACGCCCCGGTCGTCGAGATCCTCGACACCCACTGGGAGGGCGCCACCCACGCCCGGCCGACCGTCACCGCCGACGGGTCGGCGCTCCTCCTCCAGCCGACGCTGCTGCCCCGGGGACTGGAGATGACCGTCCGGGCCCTGGTGGACGGGCGGCCGAGCCTGACCATCCACGCCGAGTTGCTCGATGTGGACGTGCGCCGCCGCCCGCGCGCGGCCACGTGGGAGAAGTCCACCCGGCGCGCGGTCCTCGCCTCCGCCGTGGCCCTCCTCTCCACCGTGGTCCAGGCGGTCCTCCTAGCCCTCCAGCCCTGAACGGTCCCTGCTGAACGGTCTGTTCGGGGCGGATCCCTGCCCTCGGGAACCCTTGCCGGGGATGATTTTTGGCCCTAGGGTCGGGCCGGTCATGTTGTCGATCATGCAGGGGGTTTTGATGATCAAGGCAAGGCTCAAGGCGTCCGTCGCGGCACTCGCGGCCACGGTGCTCTTCACCGGTCTGTCCGCCGGCGAGGCGATGGCGGTGCCCAACTCGACGAAGACGTTCTCCCTTTCGGGAACGTACCAGGGCCACACCGGATACACAGAGGGCTACCTCTACTTCTACAACCGGTCCGTGGGGATCACCGGCACGGTCAAGTCGAACACCACCGGCTGTGTCCAGGTCGTCATCGCGGTGCACGCGGGCGGCAGGGAGACGGACCACCAGACCCGGACGGCATGCGGCCGGGGCACCGGCACGTCCACGGGCTTCAACTACACCGCGTCGGCCGACATCCCGGGCGGTGCCGACGAAGTGGAGATCAATCTTGCCGGGCTGGACGGCAGGGGACAGATCGACGCCGTGATCACCGGTGGCCGCTATCGTCCGTAGCCGGCCGGCTCGGTAGAGTCCCGCCGGTGAAACGGCGCAGACAGAAGAGACTCACCCGCGGACTGATCGACGCGGCCCTGACCGGGGACCTCCACCGCACCCGCGCGCTGCTGCGGGCCGGGGCCGACCCGGCGGTGCCCGACCGGGACGGCGCCACCGCCCTGTACATCGCCGCCGTCCAGGGCGAAGCACCCGTCGCCCGGCTGCTGTTGGCGGCCGGTGCACCGCCGGACGCGGAGAGCGGCCCCGGGGGAGAGGGGCACGGAGGAGGCTGGGACGGGACGCCGCTGTGCGCCGCCGCGTGCTGGGGGCACGAGGACGCGGTGCGCGTTCTCCTGGAGCACGGGGCGGACCCCGGGCTCCGGGAGGACCGGGGGAGCGGGCGGACCCCGCTGGAGTGGGTCCGGGACACCCCGGGCGGGCCCCACCCCGTGGTCGAACGGCTGCTCCTGGAGGCCCTGGCCCGCCGCCCCGGCGCATAGGACCCGGGCCTGGCCCGGTCAGGCGGCGGTGTCGATGATGGCCCAGGTCTCCCGGCCGTCGGCCGTGGCGCGGCTGCCGCAGCCCCGGGGGCCGAGCCGGTGCAGCCGGGTGAGGACGGCGGGGTCCAGCGGCGCGGGATGCGGCCGGTGGCTGAGCGCGAGGACGAGCACCAGCCGGTTCTGCTCGGAGACATGGACGCTGATCCGCCGCCCGCCGTCGGCCACCGCCGTCCGTACGAGGAACTTGACCACGTCACCGGTGCCCTCGGGCGCCGGGAGCCGCCAGGCGGTGATCTGCTCCGTCACCGCGCGGGCGGCCCGGGACGCGACCCAGGGCGCGGACTCGAACGCCCAGGCGGCGCCGGGGCGGTTGGCCATGAGGGGACGCCGCCGGGGCTCCGCCGCGACGACCGGGGGGTTCGGCGGCGGATCGGGCGGCGGCGGTGGGTTCTTCGGCGGTTTCGGGGTGTTCGGGGGCCAGTCAGGGGGGCGCGGCTTGGTCGCTGACGGGCTGCTCGGGGGTTCCACGCTCACCTCCGCGGAGTGGACGCCGGGCGCTGTGGACGGAGTCTTCCCCCACGGTGACACGCCGACGCCCGAAAGCCCCATGCCTTGTCCAGCAGATGGGACGGGCGGTATCGCATCGAGGACGGGCGGCCCTCGGGGCGCCGGGAGGGGACGGCCGCCGCGCCGCGCCCCGCCACGCCCGCCACGCCCCGCCCGGTTCGGGGGAGCTCCGCGCCACCCGCGGCACGGTGGCCGCGCGGACGACACCCGCTGTACCGACACCGGCTGTACCGAAACCCGCCGTACCGAAACCCGCTGCGCCGACCCCGGCTGCGCCACCTCGGGCGGTCATCCTCAACAGGGCCACCCGCGGATGCCCGTCGTCCGCACCGGCGCGGAGCCCACCCGGTACTCCGTCACCACCCCGCGCACCGGCCTCGACCTCCTCGTCGTCGGTCGCGGCCACAGCGACGCCGGCGGCGACGGAACGGCCGGCGGGGTCCGGGGCACCCCGGCCACCGCCGACGCGGTGATCACCGCCCACCGGGTGTCGGCCCGTTCGCCGTACGGGGCGGCGCGGCGCCGCGTCTTCCGGTAAAGACGGATATCAGCGGATAAGGCGTAGCGACTATTTCCAGCCATGTTCATATCGTGGCTCCCGGTGCCCGACGGCCCGGCGTGTCCTAAAAGATCTTCACATCGGTGGCACATCCGCGGCGGAATCTGTGCCGCGATGATCCGCAAACCGTCACCCTCCGTGCTGCCGCCTTCTGCCGCACAACCTTCTGGCCTGCGAAGACATGTCCGTATGGCAGCCAACCAAAGGAACCCCCCTACTGCGTCTGCCACCCCCCGTGTAGTCATGTCGCGGCGGCTCGCAAACACTTCGGGGGGCCGCCTCAGCCATGTCTTTGGGAGTTCATTCCGCCATGTCCAGACTCACCCGCCGCCAGGTCATCGGAGTCGTCACCGGCGCCGCCGCGGGCTCGGCGCTCGCCGGTCTCGCCACCGCGACCGCCGACAGCCCGCCCCCGGCGAAGGCCACCGCCGCGCCCGCCGGTACCACCGGACCCGACTCCTTCGACGAGGTCTTCCAGGGCCGCCGCATCCAGGGCCTGCCCGCCGAGGGCGGGGCCGCCCACGCCCGCGGCGCCCACGCCCGCGGCGCCCACGGCCACGCCGGGCACGGCCCCGCCTACCGCGTCCTCATCGACGGCCGCGAACTCCATGTCATGCGCCACGGAAAGATGGGCTGGAGCAGCGCGATCAACCACTACGAGAGGTTCGCGACCCCGCTCGACGCCGCGCGCACCGCGGTCGTCTCCCTCAAGGGCGCCGCCGTCGTCCCCTTCGACCCCACCGTCTGAGCCGGGAGCCACCGCCATGACCGTACGCAAGAACCAGGCGAACCTCACGGCCGCCGAGAAGAAGGCGTTCGTCAACGCCGTCCTGGAGCTGAAGCGCAGGGGCGTCTACGACGAGTTCGTCGCCGCCCACCGCCTCCGCTTCAACGTCGACATGAACACCGGGATATACGTGGGCCACTTCGGCCCCTCGTTCCTCCCCTGGCACCGCAAGTACCTCATCGACTTCGAGCGGGAACTGAAGAAGATCGACGCGTCGGTGTCGATCCCGTACTGGGACTGGACCGCCGACAACACCGCCGCGTCCTCCCTCTGGGCCCCGGACTTCCTCGGCGGCACCGGACGCCCCCTGGACGACCAGGTCATGGACGGGCCCTTCGCCTACTCCGGCGGCAAGTGGACGATCACCGTCCAGGCCGACAGCCGGCCCTTCCTCGCCCGTAACCTCGGCTACCGGGTCCCCACCCTGCCCACCCGCGCCCAGGTCGACGCCGCCCTCGCCATGCCGACCTACGACTCCGCCCCCTTCCGGGACGGATCGGCGGGCTTCCGCTCCGAACTCGAAGGCTCCTCGGGGTATATGAGCATGCACAACCGGGTGCACACCTGGGTCTGGGGGCAGATGGAGTCCAGCGTCTCCCCGAACGACCCGGTGTTCTGGCTGCACCACGCGTTCGTCGACAAGCTCTGGGCCGAGTGGCACGCCCTCCACCCGGGCAGCGCCGAGTACCTCCCCGCCGCCGCCACCCCCGATGTGATCGACCTGAACGAGCCCATGCCTCCGTGGACCGCGACTCCGCAGAGCGTGCTGGACCACACCCAGTTCTACATCTACGTCTGACCGACCCCGGCCGGACGCCCCCACCCGCGGTACGGGGGCGTCCGGAACCCGGGCGGGCCGTGTCTCCCCACGCGGTCCGGACCTGCCGTTCCAGCGGTGTACGATGATCTTGTTGCTCGCGCCGGTGGAAGCCGGTCGGGACACAGGCGTTGGTGGTCCAAGGAAAGACACCCCACTTCCCGTGGGGGGATGCAGGTGCAAGGCCTGCCCAGCGCTCCGCTCACCGGGCCCCGGCCTCCCCCTCAGGGAGACCGGGGCCCTCGTGTGTGCCCGGGACCCGCCGCTGAGGTGTTCAGCGGGACGCGCCCCGGGTGTTCACGGTGCTGACGGGCCCGTGGCGGCGTGTGCCGGAAACCGGACTCGATCGCCGTACGGCCGTCGAACGTGTGTCCTGGTGTCGGACCGGAAGCGTTTACTTTCCGAAGAAAGTAATATGGGGCCATGGCCGCCGAGCAGTCGAAGATCCAGCCGCTGAACGCGGGCGAAGAGGCGCTGGTCCGCTCGATCCACCGCATCGTCCACGTCCTGCCCAAGGTCATGGACGCGACCATGCAGCGCGAGCAGCGGATCTCGTTGACCGAGTACCTGACGCTGTTCCGGCTCTCCGAGGCGCCGGAGCGGAAGATGCGGATGAGCGAGCTGGCCGAGGTCTCGTTCCTGTCGCTGAGCGGTATGACCCATGTGGTCACCCGGCTCCAGGCGGAGGACCTGGTGGAGCGGGCGCGTGACGCGGAGGACCGCCGCGGCTGGCACGCGGTGCTCACCGACCGGGGCATGGCCCGGCTGCACGAGGCGGGGCCAAGCAACCTGAGCGGGGTGCGCCGCTATCTCCTCGACCATCTCCAGGGCTTCGACCTGCACGCCCTCGCCCAGGCGTTCGACGCCGTCGGGGACTCTCCGGGGGAGCCCACCGGCGGCCGTTGAGGCAGCCCGCAGCCGCGGCGGTCCGCGGCCGGAATCAGGGAGTCGCGCTCGTATGACGACACACACCAGCAACCTGGCCGCGTTCCTCCGCTCGCACCGGGAGCGGCTCAAGCCCGAACAGGTCGGACTGGCCTCCCACGGCCGACGGCGCACACCGGGCCTGCGCCGCGGGGAACTCGCCACGCTCGCCGGACTGAGCGTCGAGTATCTGGAACGTCTCGAACAGGGCCGGGACACCAACCCCTCCGGCGCGGTGCTCACCGCGCTCGCCGACGCGCTGCGCCTGTCCCAGGACGAGAAACAGCACCTCGCGCTGCTGGCCATGCGACAGCACAGCGCCACGCTCCTGCCCGTTCCGCGTCCGGTCGGCGACGATCCACGCCCCGGTGTGCGCGAACTCCTGGGCCGCCTCGACCCCACCCCGGCCTGTCTGCTCGGACCGGTCTACAACGTGGTGACCTGGAACGCGGCCTGGGAGACGGCCGCCCGCCCACTGGGCGTCCTGGATCTGGACCCGCCCGACCTCGTCCGCTACCACTTCCTGAACCCCAAGGCCCGCCGGACCTTCGACGACCAGTCATGGGCGGAGACCGCGGACGAGGTGGTCGGCTGGCTGCGGGCCGCCGAACCGGACTGGGGCGACGACGACGCCTTCCGGGCGCTGATGAGCGATGTGCACACGGTCCCCGAGTTCGCCTCCCGGTGGGCCGCCCACACGATCGCCTCCCGGCGGCCCGCCAGCAAACGCGTCTGGCACCCCGGGGCCGGGCATCTGAACATCCGTCTCGAAGTCCTCTTCGTCGGAGAGGCGAACCACTGGCTCCAGCTCTGGCTGCCGAGCGACGAGGACACCGCGACGGCCCTCGCCTCCCTCACCCGCACCCGGACGGACCCCGTGCCCCACCCCCGCGAACCCCGTGAACCGGCGCGGGAGGCATAGCCCGCGCGCCTCCCGGCCCGGCCGCAGCGTCTCCCTCCCCCTACGGGTACGGCCGCGGCGTTCCTGCGCGGCCCCCCGGCGCGCACTGTGGGACCAGGGGCGTACGACAGAGCGAAAGGAACGGTCCGATGCAGCTCAGGCCGATGCGATCGTGGATTCACCACAGCCGGGGAAAGGTGCTGCGCCAGGCGGTGACCGGACGGAGGGAACTGGGTGGCCTGTACGAGGACATGCTCACCAGGCAGGGCTTCGAGGGACGCGACGCCTATCTGTACCGGCGCGCCGAGCCGACCGCCTGGAAGCACGCGGAGGAGGGCGCGGCCAACCGCACCTACGACGGGCAACTCGTGGAGCCCACCGACCGGACCCGCCCCGACGGCGGCCCGCTGCGCCTGTTCCACCACCCCGCGCTGGCCGTCTCCGTCAGCAGGCGCGGCGCGAACATGCCCTTCTCGGTCCGCAACGTCGACGGGGACGAGCTGTACTTCGTCCACGAGGGCACCGGCACCTTCTACACCGAGTTCGGTCCGATCCCGTACGAGCCCGGCGACTACATCCTGCTGCCGAAGGGCGTCACCTACCGGATTCGTCCGTCCGGACCGGTGAACTACTTCCTCGTCGTCGAGTCGGCCGAAGAGCTGGGCTTCGCCGACACCGGCGTCCTCGGCCGCCGGGCCCCTTTCGACCCCGGTCTGCTGTACATCCCCTCCCCGGAGCTGGACGAGCTGGGCGACGGCCGGGACGAGCGCGGCACCTGGCCGGTACGGCTCAAGATCCGCGACGGGTACGCCAGCCTCGTCTACGACGCCGACCCGATCGACGTCGAGGGCTGGTCGGGCGACCTCTTCCCGTTCAAGCTGAACATCCGCGACTACCGGCCGGTCATGAGCGACCGCATCCATGTCATGCCGTCCGCGTACGCGGTCTTCGCCACCTCGACCTTCATGGTGGGCAACTTTCTGCCCCGCCCCTTCGAGACGGCCCCGGACGCGGCGGTCTTCCCGCCCTACCACCGCAATGTGGACTACGACGAGTTCACCTTTTTCCACGGCGGAACGGTGCTCGGCATGCCCATCGCCCCCGCCACCATGGCCCTCGTCCCGCAGGGGCTGCACCACGGCCTGCCCGCCGAGGTCCAGGCGCAGGTGACCGGGCGGCTGAAGCCGGGCGACCGCATCGACACCGAGGTCGTCTTCGTGGACACGACGGTGCCGCTGACCCCCACCCCGGAGGCCGAGGCCGCGCAGCGCCACGCCGAGCAGGAGTCCGGGGCCCCGACGGCACCGGTGGGGGACTGGATGTGAGGACCGGCCGCTGACGGGCGGGCCGCCACGCGCCCGCGCGGCGGGAGGGGGCGCGCCGGGCCGGGCCGGGCCGGCCGCCCGACGGGGAGACCGGTGGACCGGTCTCCCCGGCCTCGGTGTAGACATGACCTGAAGCACCCTCGCCGATCAGGAGAGAACATGTCCACCGACGCAACGATCAGGACCCGCCTCACCCCCGTCCCCCGCCCGGCTCAGGAGGCCGCGCGGGCGCTCCTCCGCGACGGCCACCGGACCCAGGCGGTGGTACGGCTGCGCAAGGGCACGGACCTCGGACTGCGGCAGGCCGCTGCCGCCGCCGACCTCCTGGCCGAGGACGTCCGGCTGCCCGCCTCGCACCAGGAGGCCATCGACGTCCTCGAAGAACTCCTGCCCGACGTCCACCGCGAGGTCGCCGCCATGGCACGCGGCGGTGACGAGGTCCGGGCCACCCGGCTGCTGCGCCAGGAGACCGGAGTCGGTCTGGTCATCGGGTACCAGCTCGTCAGCGCGCTCAACGAGCGGGACCGGAGCGCGTAGGCCGGGCCGGTCGCGTTCCCGTCCCTCGCCATCGGGGTAGGTCGACCACGGCACGAACCATCCGTGAGCCGTCTGTGTCCACGGGCGCCGTGACGACCAAGGAGGACGCCATGTCCCGACCGGACTTACCCGGTGGTTCACCCGCCACGGGCGCCGACGCCCAGCCCGCACTGAAACGGGTGATGGGCCCGGGTCTGCTGTTGCTGTTCATCGTCGGCGACATCCTCGGCACCGGGATCTACGCGCTGACCGGGCAGGTGGCCGGGGAGGTCGGGGGAGCGGCCTGGCTGCCGTTCGTCATCGCCTTCTCCGTCGCGCTGGTCACCGCCTGCTCCTATCTGGAGCTGGTCACCAAGTACCCGCAGGCCGCGGGCGCCGCCCTCTATGTGCACAAGGCGTTCCGCACCCACTTCCTGACCTTCCTCGTGTGCTTCACCGTGATGTGTTCCGGCATCACCTCGGCGTCGGCGGCCTCCCGGGCCTTCGCGGCCAATATGGTCACCGGCTTCAAGACCGACGCGGGTGACGGTGTCGTCCTGCTGATCGCGCTGGGTTTCATGGGCCTGGTGCTGTTCGTCAATCTGCGGGGTGTCACCGAGAGCCTCAAGGTCAATGTCGTGCTGACGGCCGTGGAACTGGCGGGTCTGCTGCTGGTCGTCCTGATCAGCGCCTACTTCATCGCGGGCGGGAACGCGGACTTCTCCCGGGTCGTCGCCTTCGACACCGACTCCGACAAGAGCGCCTTCCTGGCGGTGAGTACGGCGACCTCGCTGGCCTTCTTCGCCATGGTCGGCTTCGAGGACTCCGTCAACATGGCGGAGGAGACCAGGGAACCCGCGCGGATCTTCCCCCGCATGATGTTCACCGGACTGGGCATCGCCGGGCTGATCTATGTGGTGGTGTCGATCTGCGCCGTCGCTGTCGTCCCGGTGGGGCGACTCGCCGCCAGTGAGACCCCGCTGGCCACGGTCGTCCAGACGGCAGCCCCCGACTTCCCCATCTCCGATCTGCTGCCGTTCATCTCCCTGTTCGCCGTGGCCAACTCCGCGCTGATCAACATGTTGATGGCCAGCCGGCTGCTGTACGGCATGAGCAGACAGGGCGTGCTTCCCCCCTTCCTCGCCAAGGTCCACCCCGTACGGCGCACCCCGCGGGCGGCGATCCTGTTCACCACGGCCGTCGCCGTCGGCCTCATCACCTTCGTCTCACTGAACCCGGACAGCTCGGTCGTCGCCCTGCTCGGCGGTACGACCACCCTGCTGCTGCTCACGGTCTTCGCGGGCGTCCATCTCTCGGTCCTCGTCCTGCGCCGGGACAAGGTCGCGGCCCCGCACTTCCGGGCGGGCCGTGCACTGCCCGTACTGGGCGCGCTGAGCTGCCTCTATCTGGTCCTGCCCTGGTCCTCCGGCCGCCCTGCCGAGCAGTACCGCATCGCGGGGGTGCTGCTGCTGATCGGCCTGGCCCTCTGGTCGGTCACCTGGCTCACCCGCCGCACCGCCCCTGGCTCGGCCCCCGCCGCCCCTGACACCGGCCGACCGGACGGGGCCCCGCGCTGACGGGCCGGGATCGCCCAACGGCAGGAGCACGCCCGTTTCCGGACGCCCGCCCGATGTCATGGTTGAACTGACTCAGGGCCTTGCATGAGGGTGGCCGCATGGATGACACCGGTGTCGATCGCTGCCCCGTCTGCTGGTCGCCGGTAGCGGACAGCGCGCAGTGGGTCCTGCTGTCCCGGCATCAGACCTCCGAAGGCGTGCTTGAGTACTGCCTGTCGGGTTGTGGATGCGTGGCCGTCCTGCTGGGCGGGGACCTGGTGAAGGCCGTTCCCCATGGATGCGCGCGGCTCATCGGCGTACGGCCGTGGGGTCCGGGGTCCCGGATCGCGTCGAGCCGATAGCCCGACGGCCGGGAGCCCGCTGCCCGCACCCCGCTCGGCGCCGAGTGCGCCCGGTCCGGTCCTCAGCGGAACCGGGCCGGCTTCTTCAGGCGGACCTCGTCCACGCCCAGCAGACCGAGCAGCGGCACCTTGGCGGTCCGCTGGTCCGGGTCGACCACCAGGCCGGATTCGCGGATCCGGGTCAGCAGGAGTTCGGCCAGGGGGAGGACCATATGGCGGCCCCAGCACCGCTCCGACGCGTGGCCGAACGGGAGATAGCCCGGGGTCCTGTCGGGGTCGAGCCCGTCCCAGCGGTCGGGGCGGAAGGCTTCCGGGTCGTCCCACAGCGCCGGGTCCCGATGGGACAGCAGCGGGAGCAGGAGGACATCGTCCTTCGAGCCGATCCTGCCGTCGACGGCCGGGTACTCGGGGGAGGCGTTGCGCAGGAGGTTCCAGGAGGGCGGCAGCAGCCGCAGGGTCTCGTGGACGATGTTCCGGTTCGGCGTGTCGTCGGCGAAGGGGAAGCCGAGCCAGAGCGCGTTGGCCACCAGCGTGGACACGGTGAAACAGACCGGGGCGGCGGACCTGCGGTACATGCCCATGGCGTACCGGCGCTCCTGGTAGCCCATGGCTCCGGCGGTCCGGTCGGCGAGGGCGGTGCGGCCGTCGCCCTGCCGGGGCAGGCGGGGCAGGGCCGCGCCGAGCGTGACCACGGACCAGGTGAGCACCGGGGTGAGTTCGAGTCTGCGGCTCATCAGCAGGCGCAGCCGGTAGGGGTCCCGGCCGAGAATGAGGTCGCGCAGGACGTAGTGCCCGGTCCAGGGCCAGGGCCCGGACAGGTCGACGTCCTTCGGCAGGGGGTGCCTGAGCGCCTCGCGGACATCGGCGCCGACGGTCCGCGTCACCGCCGACGCCTCGGCGCGCGGTATCGAGCGCCCGAGCAGCGGCTTGAAGGTGGGCCGTTCGGTCTCCGTGGCACGGCGCGCGGCAAGCACACGGTCCATGACCTCGGGTCCCGCGACGCCGATGGTGTCGGGTTCCAGCCGGAAGACGTCCTGCCCCGTGTGGTCGTCCATGAGGGCGGCCAGCCGTGGGCTGAACACGGTGGTGCGGAGGCGCTGCGGCGATGACGTGGGCATGATTCTCCGGAAGGCGTCGGGGCGCCGCCGTCCAGCCGGACCGTGGAGCCGTGGGGGAGCGGTCCGGCCGGACGGCGGGGTCACATCGGTGATGCGGCCGAGAACGGGGACATCACCACCAGATGTACCAGGCGTACCCCTTCAGGCTCTTTCCTTCCGAGACCTTGTGGCGTATGGCGAAGAGCAGCTTGGTCACGGCACTTCCTCTCAGCGTGGATCGGACGGCACGCGGCGGTCCCGGTCCGGGGCGGCGCCGGTGCGCACCGCGTGCCGATGGCGCAGTGAGGCTTCCCTGCCCCGGCCAATGGCTAATCCAAGGAAGCGCCTCTCCCTCGTGTGTGCGAGCGGTTCTGGACCGTGCGGAAGTGTGATTGGCCCGTTAAATGCGGCTGGTTTTGGGGGTTTGGCAGTGTTCAGCCGTGGTGTGCGCACCGGCAGGTTGGCCGGATATCGGTGCCGTGAACGCTCTTTCCCGGCGTGCCGTCCCCGATGTGCACGGCGGAGGCGGGTGTCAGTCGTCCCGTACGGTGAGGCCGATGTGCCGGGCGAGCACGGGCGCCAGGTCGAAGAGCTGCGTGGTGCTGACCGTGGCGCCCTTGAGCGCCTCCACCCCGGAGCCGATGCCCAGCGCGGTGGCCTCGCGCAGGTCCACCCGGGAGAGGACGGCCCGGTCGAGGCCGACGCGGTCCAGGGCCGTCCCCGGGAAGGTGACACCGGTCAGGGACGCACCGGCGAAGTCCACGTCCCGCAGCAGGCAGTCGACGAACGAGACCTCCCGCAGCACGGCCGCGCGCAGATTGACCGAGTCGAACTTGCACTGCTGGAAGACGACCCGCTGGAGCCGGGCCCCGTGGAGCTGGGTGCCCGCCAGCAGACTGGAGAGACACGCGGTGTCCAGCCAGCCGGTCTCCGCGAGATCGGTGCCGACGGTGCGGACGTTGTGCATCCAGACGGTGTCGAGACGGGCGCGCCGGAGCCGTCCGCCCGTGAACGTCACGGAGGTGAGGGCCGACTCGCTGAAACGGGCCATCCCGGCGTCGATGTCGTCGAGGGCGAGGCCGTCGAGATGGGCCCACTCGTAGTCGCCGTCCCGTTCCGGTTCCCCCGTGAAGGGTTCCAGGCGGTGTGCGTAGGGGAGTTCGCTCAGGTCCTGCGGGGTGCGCGTGGGCATGGTGTCCTTCCGGGGCGGTCGGGGAAGATCCGGCGGGGCCGAAGATAGCCCTCCGCGCTGACACCGGCCCGCTACCGCATCCACGCCACCGCGGCGACCGCCTGGCGCTGACCCGCCGGTGGTCCACCGCCGGGCGGCCGGGACGGCCGCAGGAGGCCGGCCTCCAGGAATTACCTCTCAAAATTGTCAAAAACAGGCACGTTGCGCTCCCAAACGAGCATCTGTGTACGGGACATGGAACGTTTCGAACGCTATTCCCGTCCTGCTGGGCGAAGCGTGTGGTCGGCCGACCGCACGTCAGGTCCCACAGGGGGAAACATGCCCACGTTCACCGAACGAGCCGCCGCCGTCCTCATGACCTCCGCGCTCGCCGTGACCGGCCTCGCCGCGACCGCCACCCCGGCCGCCGCCATCCACGGCGGGCAGAACACGACCGTCACGGACCACCCGTACGCGATGCTGCTGGTCACCCCCGACGGCCAGCAGGTCTGCGGCGGCACACTGGTGGAGCCCACCAAGGTGCTCACGGCCGCGCACTGCGTCGACGGCCTGGCCACGACCGATCTCCAGGTCATCGGCGGCCGTACGGAGGTGGCGGGCACCAAGGGAACCGTGCGGGCCATCCGCTCCATCGCCCTGCACCCCCGGTACAACGAGGGCGGCTTCCTGGCCAACGACGCCGCCGTGATCACGCTCACCGCGTCGATGCCGTACCGGACGCTGCCCGTCGCGGGCCCGAAGGACACCGCCCTCTACGCCGTCGGCAGCACCGCGAAGGCCGTGGGCTGGGGCCGGATCGCCCGTGACACCCCGGCCACCCGGCTGAAGTCGGCGCAGCTCACCCTCTCGCCGATCGCCGCGTGCGACCCGTTCACCGACACCGGCGACTCGCTCGCCCGCAAGGTCTGCGGCACCCCGCCCGCGGGCACCCAGAACAGCATCTGCCGGGGCGACTCGGGCGGCCCGCTCATCGCGGGCGGCAAGGTGATCGGCGTGGTCACCACCGGCAACAAGTACTGCGACACCGAGCACCTGAAGTCGGTCTTCACCCGCACCAGCGCCGTCGCGGCCGACCTCGGGCTGCGCACCGGCTGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP016560|572470:608462|584129_585737_-|WP_009999522.1|tail|DBSCAN-SWA
MPNYLSPGVYVEEVASGSRPIEGIGTSVAAFVGLAPTGVLNEPTLVTNWSQYVAEFGEFTDGYYLAQAVYGFFNNGGSAAYVIRIGGTSDGTYPAAAPGAGAVADAPAQLPPGRPAALGPFTVSAVAAGADGGGLTVEVAHPEGEGNADRFTLVVKDGDTVVESFDVSHRKSAKNYVVTQVRQRSRTIVIEEARTGGQLAKPEPQTVALEPPAPAPGTAGGAAPVVPDAAGGGLGPTRFIGDSADRTGFGGLEAIDAVSMVAVPDLMSAHQRGLIDLEQVKAVQLGLIAHCELMGDRMAVLDTPPGLNAQQVRAWRMETAGYDSRYAAVYYPWVKIFDPSTGQTRSVPPSGHMAGVWARNDFERGVHKAPANEVVRGAVDLDLQITRGEQDLLNPTGINCIRAFPGRGVRVWGARTLSSDAAWRYLNVRRYFNYLEESILVGTQWVVFEPNDQALWARIRRNISAFLVTEWRSGALFGQRPEDAFYVKCDEETNPPESVDLGRVVCEIGIAPVKPAEFVVFRMAQISGGGAELEE
>NZ_CP016560|572470:608462|595099_595726_+|WP_003957059.1|DBSCAN-SWA
MVMLAESWSDPSVVVSIAALLATVAVGVVAAVVARRASFAKRRLTHDLAPPARLLPPGSGDRLVVTCDGSALRDPHIAEVHLANTGRRDIASGLFDGARPIRFELNAPVVEILDTHWEGATHARPTVTADGSALLLQPTLLPRGLEMTVRALVDGRPSLTIHAELLDVDVRRRPRAATWEKSTRRAVLASAVALLSTVVQAVLLALQP
>NZ_CP016560|572470:608462|575090_575540_-|WP_003963524.1|DBSCAN-SWA
MSEQFIGAGWSFPLRIDPGGGIALVRRDREIEESMRLVLATAPGERPMRPEFGCAVHDLVFAPVNDATAGRIQHEVRTSLDRWEPRIEVRDVTVTPAPDDPTVLHIDVRYSVRGTNNPRSLVFPFYVIPSEAPYEGPGGHPAGGESERL
>NZ_CP016560|572470:608462|583598_584042_-|WP_003963532.1|tail|DBSCAN-SWA
MSLQPGDALVAHNFGIQIDGVMVEFLQEVSSLTMDQDVIEYKQVSANGQPMVKKLPGARKAGECTVVRGATQSAVFTQWIRESIEGNMGSARKNASIIFMDYERRPVKRYNLSNAWCSKVEVSSAKAGDTSALTETITITFEELTLG
>NZ_CP016560|572470:608462|602803_603181_+|WP_003963542.1|DBSCAN-SWA
MSTDATIRTRLTPVPRPAQEAARALLRDGHRTQAVVRLRKGTDLGLRQAAAAADLLAEDVRLPASHQEAIDVLEELLPDVHREVAAMARGGDEVRATRLLRQETGVGLVIGYQLVSALNERDRSA
>NZ_CP016560|572470:608462|595787_596282_+|WP_003957060.1|DBSCAN-SWA
MIFGPRVGPVMLSIMQGVLMIKARLKASVAALAATVLFTGLSAGEAMAVPNSTKTFSLSGTYQGHTGYTEGYLYFYNRSVGITGTVKSNTTGCVQVVIAVHAGGRETDHQTRTACGRGTGTSTGFNYTASADIPGGADEVEINLAGLDGRGQIDAVITGGRYRP
>NZ_CP016560|572470:608462|596782_597016_-|WP_106428661.1|DBSCAN-SWA
MVKFLVRTAVADGGRRISVHVSEQNRLVLVLALSHRPHPAPLDPAVLTRLHRLGPRGCGSRATADGRETWAIIDTAA
>NZ_CP016560|572470:608462|592468_593215_-|WP_003963537.1|DBSCAN-SWA
MIHEMDEALRRLLRGGALPEGTGEVAFDAPTRDWAARRNAPTVNAYLYDIREDVARRERGARAERDERGVVVRQRQPMRWYRLSYLVTAWTTRPEDEHRLLSGVLATLLPHETLPAGSVPAALSEYRIPIPLTVAVPPAESRSLADIWSALGGELKPSLDVVITTPFPVTPVWEVGPPVTEIEVTVRDRQGPDAARGRPRVIRAEARTRPGNGTERAGAAATAGTAEETGAAEPGPGAKRKPERGTES
>NZ_CP016560|572470:608462|597644_597869_+|WP_003957064.1|DBSCAN-SWA
MPVVRTGAEPTRYSVTTPRTGLDLLVVGRGHSDAGGDGTAGGVRGTPATADAVITAHRVSARSPYGAARRRVFR
>NZ_CP016560|572470:608462|597294_597477_-|WP_003957063.1|DBSCAN-SWA
MAGVAGRGAAAVPSRRPEGRPSSMRYRPSHLLDKAWGFRASACHRGGRLRPQRPASTPRR
>NZ_CP016560|572470:608462|604835_605078_+|WP_003957073.1|DBSCAN-SWA
MDDTGVDRCPVCWSPVADSAQWVLLSRHQTSEGVLEYCLSGCGCVAVLLGGDLVKAVPHGCARLIGVRPWGPGSRIASSR
>NZ_CP016560|572470:608462|594352_595042_+|WP_003957058.1|DBSCAN-SWA
MYSHENARTSGPTAAERPERKAQRGLLAWQGTAGNAAVVQMLRRAGHPWAQGGGDGGHAQGDRAPDQEQHRHGPGCDHRRTGPAAPPVQRSTAEPVQRSAVHDVLRTPGQPLDTTTRTEMEARLGADFSDVRVHRDTAAQASAAEVNARAYTSGSHVVLGGGGTDKHTLAHELTHVIQQRQGPVAGTENGSGLRVSDPSDRFEREAEANAARVMRGPVPERDGQGAAQP
>NZ_CP016560|572470:608462|605140_606196_-|WP_003963544.1|DBSCAN-SWA
MPTSSPQRLRTTVFSPRLAALMDDHTGQDVFRLEPDTIGVAGPEVMDRVLAARRATETERPTFKPLLGRSIPRAEASAVTRTVGADVREALRHPLPKDVDLSGPWPWTGHYVLRDLILGRDPYRLRLLMSRRLELTPVLTWSVVTLGAALPRLPRQGDGRTALADRTAGAMGYQERRYAMGMYRRSAAPVCFTVSTLVANALWLGFPFADDTPNRNIVHETLRLLPPSWNLLRNASPEYPAVDGRIGSKDDVLLLPLLSHRDPALWDDPEAFRPDRWDGLDPDRTPGYLPFGHASERCWGRHMVLPLAELLLTRIRESGLVVDPDQRTAKVPLLGLLGVDEVRLKKPARFR
>NZ_CP016560|572470:608462|573144_575091_-|WP_003963523.1|plate|DBSCAN-SWA
MALPAPHLDDRRFQQFVDDAKRYIQQRCPEWSDHNVSDPGVTLIEAVAHMADQIVYRLNRVPEKNRLAFLDLLGVTLFPPSAARAPVTFWLSAPQPEPVVLPTGTEVATLRTEAEEAVVFSTTEDLTVVPCALTHILRQPEGAPAEDRSQDVLGGTDTAVFGDPPRPGDQVLFGLSAAAPRCVLVLRLDSRVDGVGVDPRQPPLVWEAWTADGWRGCEVDTDSTGGLNRPGEVILHLPAGHAVSRQTRVDAGWVRCRVVEAAAGQPFYSESPTVRAASAFTIGGTTDAAHSERVRDEILGESEGVPGQRLRLAHAPVVGGLTLEVSEGEGWRRWEVVDEFAASGPADRHAVLDAATGEIRFGPGVRTADGSLRQYGAVPRKGATVRAARYRTGGGRAGNVARGSLRVLRSSIPYIARVENREGARGGVDGETVEEAKTRAPIALRAQERAVTARDYEELARRAAPEAARIACLAADRAEAGDNAVRVLVVPQAVPDVGRRLRFEQLVPGDELLERVTSFLDERRPIGTRLAVGPPFYQGVTVVATLHAFRAVRIDWVRDAALDALYAYLDPLTGGAHGEGWPFGRPLRAGEIFAALQRVPGVELVDEVQLHPADPLTGRRGDATDRIDLVPSALLFPFDHRVRVVEAR
>NZ_CP016560|572470:608462|583107_583599_-|WP_003963531.1|DBSCAN-SWA
MRREAPGAPGSAGAPGFPGTGGVTGVHEATGGGGAGGRSAPLRTEFAFELPRGYLDESGTVHRHGAMRLATARDELVPLRDIRVRENPAYLSVVLLGRVITRLGTLPAVHDGTVEQMFASDLAFLQDFYRQINAEGHTRAAVACPHCEESFEVELAGSRLGES
>NZ_CP016560|572470:608462|590348_592472_-|WP_003963536.1|DBSCAN-SWA
MTGPDRDTVAAAPRGPSAAGGPATGAAGELLTVLEELRRAVAERVAARSAADPTAHDPLRGMYMTHESAVELAAVPVGSGAGPVPGLPPLGARLGSLVDRFGLSGFDGWILLAGLAPDVDGRFEALYGYLNDDVGRRRATVSLALELLGTGPWEPVARARFHPDAPLIAGGLLTLEDEERPLPGRAVRVPERVIAHLLGDERLDALLSDAGVEWLPATAGSSPSGTDGQNAKQDTGQDTGQDTERDTGHETAARIAAYRRPVRVHLRDKGDGDGADAVTGALRAAGRSVLRFRPRGDDKDAGVARALVREARLRGAGTALVVEPLPKEPGPLVRTLTEQQDVTVVLAGPVAYDPGWAPRSVVIPVEDVSAGADPLSVWRAELPDYAGDLATAVGAYRAGGERVRRAARAAVTLADFEGVPVGPGHVRRSARLLSAPLLGRFARCVRPAVGFTDLVLPGEPLGMLGELVGRARHRDRVLGEWRLRTGGGRGRGVVALFAGDSGTGKTLAAEVVAGELGLDLYVIDLSSVVDKYVGETEKNLERIFAEIDRTDVVLLFDEADAVFGKRSEVRSSHDRYANLESAFLLQRLESFDGIAILTTNLRANIDEAFTRRLDMVVDFPFPDPEARLRLWRSSLAGAPREPGLDDGLAAFAKEFELAGGSIRAGAATAAYLAAARGGAVTSDDVRAGARREYLKSGRLVPGTGWGP
>NZ_CP016560|572470:608462|578800_579016_-|WP_157849255.1|DBSCAN-SWA
MVQPRATPPPQPPQPPQPQPPQPPPPADDTAADPTPQDLDRLARRLVAPLSRLLRAELRGDRERVGRLRDG
>NZ_CP016560|572470:608462|579506_579860_+|WP_009999520.1|DBSCAN-SWA
MEDRRREPPGPGPSGARSRVVRLTTGRRWTNGPRSSGAGLPAPVGETGAGRAGDASGAGGIARGFPTAAIRREGTTGRGDTVNGAPPTTARTTGAGAPLPPLTAGPDTPVPSTAGAR
>NZ_CP016560|572470:608462|575607_577443_-|WP_003963526.1|DBSCAN-SWA
MSETTFTTLLQVSVGGAELPEPLALLLIEGWVDASLNVPSAFQLTFSDKDGLLTTEFPRLTIGAPVVLHPFTDGRAGPPMLTGEVTALEVDADPASGRHLVVRGYDPAHRLLRNRPVVGYAQMTASDIVRRVAARCGVALGRVDATTTVYELATQPGTTDWDFLSGLAAENDVRLACDGDGRLEFTALPSAAGAPSDATPAAQSPYVLDFGANTLHSRVAMTAADQVDRVSVRGWDMLTRRTLVAPAPATANPGITAGLTPGQVTPLFGQAEATATRPPFTTQAQVTQAARALADDITGSFAELEVAVTGNPELRPGVPVSVNGAGTPFEGKYTATGVRHVFASGQPFTTWLTVSGRQFRSLYGLASGATASAPPMPGVALAVVTNTKDPLGLGRVRLRFPWLSDTYESDWSRVAQFGGVGGGGLLLPEVDDEVLCAFDRGSLAHPYVLAGLYNGVDRPPEEPKGRPPVDPTSGRVNWRALTARSGHTVELIESGGPGAAAGSGGGILLQTGGNGLRIELDEASTALTIGSDGSVTISGTRAVRVESAGDLTLKAGRSLSLEAVGQVAVKAGASVQLDAIGSVSLKAAVNASVTATTVTLTGATLRNGVPF
>NZ_CP016560|572470:608462|582952_583171_-|WP_106432077.1|DBSCAN-SWA
MPALRGVVRGGAGREPPGGIVTYAADRIEEETAYLAFHLHWGMDSILDLEHADRRAYVRRVAALVGQDEGQG
>NZ_CP016560|572470:608462|586117_588115_+|WP_009999523.1|DBSCAN-SWA
MPGSGEAPGGLRFRLLGPLQGEQNGRHLPLGPPQQRAFLAVLLLRVDRPVSTAELIDALWGERLPDRAVGTLRTYVSRLRRLLEPERPARSAATVLVSTDDGYLLRVPPGAVDTVEFERRTSAAGRLRAAGDTESAHGELDAALELWSGTPLTGLPGPHAARQRDRLTELWLTAREDHFHCSLALERHTATIPPLRAFAAEHPLRERTQALLMQALHRDGRQAEALGVYEETCRALAGELGVGPGRELSALHTRLRTAAPGELPEARATVVRVRVPRSPAAPGDTLERVLAETRAALVRFRPDLVLTAPRPGPPPPSAAPPPLPELSLPGLTEDFQQRIADAVAAALSALTDTDADIGTENGTGTGTGTGTGTGTDNGTGRTANGRVPAALDATGELLTTWSRLVQGTADCHRPIAPAHRLLAAARRHGDPSAAGRALHILATAPPVGIDDLGRNIDRLRRALRHSTSPGDTPASAEGALDLALLLVLVGRPREALPWSERARDRYADLDAPHHRARALALTARAHALRGDAEAAGRAGDQALDEARALADPHTLGSVLHHVGCARLALGDHGRAVAHLREARYHHRRTGQPRWEAHAWSRLAEGALAQRRPEEAAACATQALALERTVRDPICRGLALAARRQALHILDTHPPGTPLDLPAPPL
>NZ_CP016560|572470:608462|578296_578734_-|WP_003963528.1|tail|DBSCAN-SWA
MPATPDPGSTVFFTLTVDGQNLGLFNGCEGLSSTVEIERHQEGGNNGFVWQLPTRVNFSTIRLTRPLTADTARVATWISSVTTGITRPTAQIAALRADGSIVAQWGLMEVLPVSWTGPTLNPESPAVATETLEIAHHGFTDAGGA
>NZ_CP016560|572470:608462|607685_608462_+|WP_003963547.1|protease|DBSCAN-SWA
MPTFTERAAAVLMTSALAVTGLAATATPAAAIHGGQNTTVTDHPYAMLLVTPDGQQVCGGTLVEPTKVLTAAHCVDGLATTDLQVIGGRTEVAGTKGTVRAIRSIALHPRYNEGGFLANDAAVITLTASMPYRTLPVAGPKDTALYAVGSTAKAVGWGRIARDTPATRLKSAQLTLSPIAACDPFTDTGDSLARKVCGTPPAGTQNSICRGDSGGPLIAGGKVIGVVTTGNKYCDTEHLKSVFTRTSAVAADLGLRTG
>NZ_CP016560|572470:608462|603291_604737_+|WP_003963543.1|DBSCAN-SWA
MSRPDLPGGSPATGADAQPALKRVMGPGLLLLFIVGDILGTGIYALTGQVAGEVGGAAWLPFVIAFSVALVTACSYLELVTKYPQAAGAALYVHKAFRTHFLTFLVCFTVMCSGITSASAASRAFAANMVTGFKTDAGDGVVLLIALGFMGLVLFVNLRGVTESLKVNVVLTAVELAGLLLVVLISAYFIAGGNADFSRVVAFDTDSDKSAFLAVSTATSLAFFAMVGFEDSVNMAEETREPARIFPRMMFTGLGIAGLIYVVVSICAVAVVPVGRLAASETPLATVVQTAAPDFPISDLLPFISLFAVANSALINMLMASRLLYGMSRQGVLPPFLAKVHPVRRTPRAAILFTTAVAVGLITFVSLNPDSSVVALLGGTTTLLLLTVFAGVHLSVLVLRRDKVAAPHFRAGRALPVLGALSCLYLVLPWSSGRPAEQYRIAGVLLLIGLALWSVTWLTRRTAPGSAPAAPDTGRPDGAPR
>NZ_CP016560|572470:608462|598654_599476_+|WP_003957066.1|DBSCAN-SWA
MTVRKNQANLTAAEKKAFVNAVLELKRRGVYDEFVAAHRLRFNVDMNTGIYVGHFGPSFLPWHRKYLIDFERELKKIDASVSIPYWDWTADNTAASSLWAPDFLGGTGRPLDDQVMDGPFAYSGGKWTITVQADSRPFLARNLGYRVPTLPTRAQVDAALAMPTYDSAPFRDGSAGFRSELEGSSGYMSMHNRVHTWVWGQMESSVSPNDPVFWLHHAFVDKLWAEWHALHPGSAEYLPAAATPDVIDLNEPMPPWTATPQSVLDHTQFYIYV
>NZ_CP016560|572470:608462|588581_590261_+|WP_003963535.1|DBSCAN-SWA
MTLWTSLDPPARTVEPGGHATARLRLRNTGDTVEEYRISLVGAPAGWARAEPDVLRLYPGTEGTAEISFAPPRTSDAPAGPAPYGIRVEPRDQPELRTVVEGQVTVTPFAQIKAELLPPNLIGRFRGRARIAVDNLGNTPLTASLTVRDESNGLTFDLQPGAVQIGPGRAAFADLVVRPQEIRWTGTAQEHRLTLSVRRSGDEHGQDLNGVFDQRPVLPPWLVVVGGLLVAACVAFVAIWLAFTPTFGSSAGETRAAGRQPLPQGEKNALPPAPDAPPGEPLKERPSGSDGGSDPGPGPGSGPDRGAPAGGGDPGAGSPDRGGAPAGPDRRPAAGGDKGPSTPDRRPAPRTTKPQPAKPRPTPPRPAPVGPPWRKGYQSDDIVLFAQHRLSTLGSRNPCNLAKNFTPGVIDDRTDRSLRCYQRAVMEHPKLTRQLTRTDPYGTLGRATLASMWTQSIKPSDVTLGSENIEVTKLNAALWWATQAEISDGDLHRDRAYARLGIAYFSGKGRAVTPFNKSVEHMVRVYQQRVGLKATGQVNWDTLFALLGGSVHRPGVPGR
>NZ_CP016560|572470:608462|577495_578293_-|WP_003963527.1|DBSCAN-SWA
MSTPVGNPSAGLSRAVLAILSPPTDLAGDPGGPLGEVRFRFNPSQLRLGRSASWTTPPAVAYTRGAPAKFTGAHPANLRLEVFLDASGTPGAATVQDQVALLLSCCEVTPQSIAAKAPSPPWVRFSWGAFSTVQFTAYVTSVDATYTLFSPNGMPLRATCSLALTEIATATKRQNPTSGALSAHRIHRTVAGDTLPSLAWREYGDAGRWRLIAEANSVDDPMRLRPGTELLLPAASERETTSGGRAAGMGGRAAHGPDEAKGRAR
>NZ_CP016560|572470:608462|598176_598638_+|WP_003957065.1|DBSCAN-SWA
MSLGVHSAMSRLTRRQVIGVVTGAAAGSALAGLATATADSPPPAKATAAPAGTTGPDSFDEVFQGRRIQGLPAEGGAAHARGAHARGAHGHAGHGPAYRVLIDGRELHVMRHGKMGWSSAINHYERFATPLDAARTAVVSLKGAAVVPFDPTV
>NZ_CP016560|572470:608462|599917_600400_+|WP_003957067.1|DBSCAN-SWA
MAAEQSKIQPLNAGEEALVRSIHRIVHVLPKVMDATMQREQRISLTEYLTLFRLSEAPERKMRMSELAEVSFLSLSGMTHVVTRLQAEDLVERARDAEDRRGWHAVLTDRGMARLHEAGPSNLSGVRRYLLDHLQGFDLHALAQAFDAVGDSPGEPTGGR
>NZ_CP016560|572470:608462|600452_601340_+|WP_003957069.1|DBSCAN-SWA
MTTHTSNLAAFLRSHRERLKPEQVGLASHGRRRTPGLRRGELATLAGLSVEYLERLEQGRDTNPSGAVLTALADALRLSQDEKQHLALLAMRQHSATLLPVPRPVGDDPRPGVRELLGRLDPTPACLLGPVYNVVTWNAAWETAARPLGVLDLDPPDLVRYHFLNPKARRTFDDQSWAETADEVVGWLRAAEPDWGDDDAFRALMSDVHTVPEFASRWAAHTIASRRPASKRVWHPGAGHLNIRLEVLFVGEANHWLQLWLPSDEDTATALASLTRTRTDPVPHPREPREPAREA
>NZ_CP016560|572470:608462|593358_594009_-|WP_003957057.1|DBSCAN-SWA
MGQLPSERIRVGVQAADPIGRAGVRSLLRHQGSVEVVEESGAEGCAGVVVMVVDRLDEVVAAELRRISRGLERPVVLVARELREDDLLTVVECGVRAILWRHEATEARLLKAVHRAARGESDLPIDLLNQLLTQVGRLRRCGSEESGTGSVPLLGMAPREVDVLRLIADGLDTRQISQKLAYSERTIKNILHGVMTRLQLSNRAHAVAFALREGYI
>NZ_CP016560|572470:608462|572470_573073_-|WP_106432093.1|tail|DBSCAN-SWA
MASAHPLGERLPAVYAEDELAQRFVSGLDVVLAPLFNVLDCLEAYFTPSLAPEDFVDWLADWVGPELDGSEPLEARRRAVASAVALHRLRGTVEGLARTVRQAFGARPEIVESGGAVWSARPLGPFPGHPVASLLVRLTVPEPERVDRYRLHAVVAAARPAHLPFTVEVLPSDPAGPAGPARPTDSSPPSLPPSPLPEGH
>NZ_CP016560|572470:608462|606707_607367_-|WP_003963545.1|DBSCAN-SWA
MPTRTPQDLSELPYAHRLEPFTGEPERDGDYEWAHLDGLALDDIDAGMARFSESALTSVTFTGGRLRRARLDTVWMHNVRTVGTDLAETGWLDTACLSSLLAGTQLHGARLQRVVFQQCKFDSVNLRAAVLREVSFVDCLLRDVDFAGASLTGVTFPGTALDRVGLDRAVLSRVDLREATALGIGSGVEALKGATVSTTQLFDLAPVLARHIGLTVRDD
>NZ_CP016560|572470:608462|601468_602644_+|WP_003963541.1|DBSCAN-SWA
MQLRPMRSWIHHSRGKVLRQAVTGRRELGGLYEDMLTRQGFEGRDAYLYRRAEPTAWKHAEEGAANRTYDGQLVEPTDRTRPDGGPLRLFHHPALAVSVSRRGANMPFSVRNVDGDELYFVHEGTGTFYTEFGPIPYEPGDYILLPKGVTYRIRPSGPVNYFLVVESAEELGFADTGVLGRRAPFDPGLLYIPSPELDELGDGRDERGTWPVRLKIRDGYASLVYDADPIDVEGWSGDLFPFKLNIRDYRPVMSDRIHVMPSAYAVFATSTFMVGNFLPRPFETAPDAAVFPPYHRNVDYDEFTFFHGGTVLGMPIAPATMALVPQGLHHGLPAEVQAQVTGRLKPGDRIDTEVVFVDTTVPLTPTPEAEAAQRHAEQESGAPTAPVGDWM
>NZ_CP016560|572470:608462|596308_596764_+|WP_003957061.1|DBSCAN-SWA
MKRRRQKRLTRGLIDAALTGDLHRTRALLRAGADPAVPDRDGATALYIAAVQGEAPVARLLLAAGAPPDAESGPGGEGHGGGWDGTPLCAAACWGHEDAVRVLLEHGADPGLREDRGSGRTPLEWVRDTPGGPHPVVERLLLEALARRPGA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106432093.1|572470_573073_-|tail	phage tail protein	NA	NA	NA	NA
WP_003963523.1|573144_575091_-|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_003963524.1|575090_575540_-	GPW/gp25 family protein	A0A1D8KR06	Synechococcus_phage	2.9e-10	30.1
WP_003963526.1|575607_577443_-	VgrG-related protein	NA	NA	NA	NA
WP_003963527.1|577495_578293_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_003963528.1|578296_578734_-|tail	phage tail protein	NA	NA	NA	NA
WP_157849255.1|578800_579016_-	hypothetical protein	NA	NA	NA	NA
WP_009999520.1|579506_579860_+	hypothetical protein	NA	NA	NA	NA
WP_106432077.1|582952_583171_-	hypothetical protein	NA	NA	NA	NA
WP_003963531.1|583107_583599_-	hypothetical protein	NA	NA	NA	NA
WP_003963532.1|583598_584042_-|tail	phage tail protein	NA	NA	NA	NA
WP_009999522.1|584129_585737_-|tail	tail protein	J9PVC2	Bacillus_phage	3.5e-69	34.6
WP_009999523.1|586117_588115_+	transcriptional regulator	NA	NA	NA	NA
WP_003963535.1|588581_590261_+	hydrolase	NA	NA	NA	NA
WP_003963536.1|590348_592472_-	ATP-binding protein	A0A0R6PCP6	Moraxella_phage	1.6e-18	30.4
WP_003963537.1|592468_593215_-	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_003957057.1|593358_594009_-	response regulator transcription factor	NA	NA	NA	NA
WP_003957058.1|594352_595042_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_003957059.1|595099_595726_+	hypothetical protein	NA	NA	NA	NA
WP_003957060.1|595787_596282_+	hypothetical protein	NA	NA	NA	NA
WP_003957061.1|596308_596764_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_106428661.1|596782_597016_-	hypothetical protein	NA	NA	NA	NA
WP_003957063.1|597294_597477_-	hypothetical protein	NA	NA	NA	NA
WP_003957064.1|597644_597869_+	hypothetical protein	NA	NA	NA	NA
WP_003957065.1|598176_598638_+	tyrosinase	NA	NA	NA	NA
WP_003957066.1|598654_599476_+	tyrosinase family protein	NA	NA	NA	NA
WP_003957067.1|599917_600400_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003957069.1|600452_601340_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003963541.1|601468_602644_+	homogentisate 1,2-dioxygenase	NA	NA	NA	NA
WP_003963542.1|602803_603181_+	hypothetical protein	NA	NA	NA	NA
WP_003963543.1|603291_604737_+	APC family permease	NA	NA	NA	NA
WP_003957073.1|604835_605078_+	hypothetical protein	NA	NA	NA	NA
WP_003963544.1|605140_606196_-	cytochrome P450	NA	NA	NA	NA
WP_003963545.1|606707_607367_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_003963547.1|607685_608462_+|protease	serine protease	Q6JPG5	Neodiprion_lecontei_nucleopolyhedrovirus	1.5e-14	28.5