CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012397	Salmonella enterica strain FORC_019 plasmid pFORC19, complete sequence	0 crisprs	cas14j	0	0	3	0
NZ_CP012396	Salmonella enterica strain FORC_019 chromosome, complete genome	2 crisprs	PD-DExK,WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,csa3,DEDDh,DinG	0	12	8	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2659 : 47362

Escherichia_phage(21.43%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067855.1\|2659_3364_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000018329.1\|3514_4330_+	aminoglycoside O-phosphotransferase APH(3')-Ia	A0A193DTG4	Autographa_californica_nuclear_polyhedrosis_virus	6.1e-163	100.0
WP_001067855.1\|4519_5224_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_014837927.1\|5260_6388_-	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_000248278.1\|6438_6666_-	hypothetical protein	NA	NA	NA	NA
WP_000951934.1\|6689_6881_+	hypothetical protein	NA	NA	NA	NA
WP_000587837.1\|7362_7905_-	AAA family ATPase	NA	NA	NA	NA
WP_000557454.1\|7917_8778_-	aminoglycoside N-acetyltransferase AAC(3)-IId	NA	NA	NA	NA
WP_077951587.1\|8920_9256_+	hypothetical protein	A4KWT9	Enterobacteria_phage	2.8e-37	100.0
WP_001067858.1\|9201_9906_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000077926.1\|10060_10342_-	hypothetical protein	NA	NA	NA	NA
WP_000398480.1\|10391_10583_-	hypothetical protein	NA	NA	NA	NA
WP_001371937.1\|10674_11046_-	hypothetical protein	NA	NA	NA	NA
WP_000341066.1\|11388_11781_+	hypothetical protein	NA	NA	NA	NA
WP_024136327.1\|12412_12706_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000088046.1\|12710_14036_+	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_000134171.1\|14096_14303_+	hypothetical protein	NA	NA	NA	NA
WP_000985911.1\|14404_14815_+	hypothetical protein	NA	NA	NA	NA
WP_001572439.1\|14827_15643_+	HNH endonuclease	G0X580	Salmonella_phage	1.1e-15	36.5
WP_001043843.1\|15896_16322_+	hypothetical protein	NA	NA	NA	NA
WP_001572440.1\|17066_17366_+	hypothetical protein	NA	NA	NA	NA
WP_032192809.1\|17678_19718_-	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	2.5e-24	24.8
WP_001572342.1\|19714_20701_-	hypothetical protein	NA	NA	NA	NA
WP_001194555.1\|21731_21935_+	hypothetical protein	NA	NA	NA	NA
WP_001287392.1\|22276_22681_-	H-NS histone family protein	NA	NA	NA	NA
WP_000175476.1\|23178_23415_-	hypothetical protein	NA	NA	NA	NA
WP_001572344.1\|23456_23912_-	hypothetical protein	NA	NA	NA	NA
WP_000490638.1\|23971_24637_-	hypothetical protein	NA	NA	NA	NA
WP_001426317.1\|24694_25075_-	hypothetical protein	NA	NA	NA	NA
WP_000193209.1\|25717_26536_+	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_001572381.1\|26532_27738_+	hypothetical protein	NA	NA	NA	NA
WP_001201739.1\|28559_28943_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.1e-13	36.3
WP_000609174.1\|28939_29287_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.7e-59	95.7
WP_001000406.1\|29336_30872_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	4.8e-262	88.1
WP_000833382.1\|32032_33460_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	3.4e-100	52.3
WP_001572389.1\|33674_34190_+	thermonuclease family protein	A0A1X6WF84	Pacmanvirus	2.1e-07	38.6
WP_000975182.1\|34192_35089_+	hypothetical protein	NA	NA	NA	NA
WP_015059496.1\|35310_35544_+	hypothetical protein	NA	NA	NA	NA
WP_001572393.1\|36205_36436_+	hypothetical protein	NA	NA	NA	NA
WP_000185304.1\|36772_37234_+	hypothetical protein	NA	NA	NA	NA
WP_000074418.1\|37263_37671_+	hypothetical protein	NA	NA	NA	NA
WP_062873134.1\|37721_38015_-	hypothetical protein	NA	NA	NA	NA
WP_066038544.1\|38007_38250_-	hypothetical protein	NA	NA	NA	NA
WP_000608644.1\|38473_39736_+\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_000239590.1\|39991_40867_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
WP_001393253.1\|40913_41246_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
WP_031613424.1\|41471_41822_-	hypothetical protein	NA	NA	NA	NA
WP_001351729.1\|43686_44079_+	cysteine hydrolase	NA	NA	NA	NA
WP_000058717.1\|44216_45101_+	EamA family transporter	NA	NA	NA	NA
WP_000804064.1\|45132_46332_-	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_000164043.1\|46437_47088_+	tetracycline resistance transcriptional repressor TetR(A)	NA	NA	NA	NA
WP_000844627.1\|47119_47362_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

52853 : 70517

Escherichia_phage(40.0%)

transposase,integrase

attL 57115:57127|attR 70734:70746

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000935452.1\|52853_54158_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_001067855.1\|54204_54909_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000098781.1\|55211_56876_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_077907510.1\|56808_57834_+	AAA family ATPase	NA	NA	NA	NA
57115:57127	attL	NA	NA	NA	NA
WP_001121400.1\|58022_59060_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_000346690.1\|59667_60561_+	virulence genes transcriptional activator SpvR	NA	NA	NA	NA
WP_001576629.1\|60734_60899_+	glycoside hydrolase family protein	A0A0M4R365	Salmonella_phage	3.3e-12	63.0
WP_001676649.1\|61072_61840_+	virulence protein SpvA	NA	NA	NA	NA
WP_001676648.1\|62021_63797_+	SPI-2 type III secretion system effector NAD(+)--protein-arginine ADP-ribosyltransferase SpvB	NA	NA	NA	NA
WP_001122242.1\|64077_64803_+	type III secretion system effector phosphothreonine lyase SpvC	NA	NA	NA	NA
WP_001676646.1\|65064_65715_+	SPI-2 type III secretion system effector cysteine hydrolase SpvD	NA	NA	NA	NA
WP_000064919.1\|65841_66267_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.4e-24	50.4
WP_001541541.1\|66323_66674_+	helix-turn-helix domain-containing protein	A0A077SLN2	Escherichia_phage	1.9e-44	80.5
WP_000900095.1\|66740_67301_-	inverse autotransporter beta domain-containing protein	NA	NA	NA	NA
WP_071530243.1\|67456_67744_+	hypothetical protein	NA	NA	NA	NA
WP_000905606.1\|68020_68506_-	membrane protein	NA	NA	NA	NA
WP_001541544.1\|68499_69009_-	CaiF/GrlA family transcriptional regulator	NA	NA	NA	NA
WP_000545756.1\|69012_69726_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000082169.1\|69734_70517_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.6e-51	91.1
70734:70746	attR	NA	NA	NA	NA

DBSCAN-SWA_3

103583 : 110491

Escherichia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000925628.1\|103583_104006_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.0e-29	52.4
WP_000457542.1\|104005_105280_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	3.9e-156	64.5
WP_000064277.1\|105361_106336_-	ParB/RepB/Spo0J family partition protein	A0A1B0V750	Salmonella_phage	5.1e-84	53.5
WP_000427676.1\|106335_107541_-	ParA family protein	A0A077SL49	Escherichia_phage	1.5e-162	69.3
WP_000728919.1\|107955_108897_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	4.7e-74	54.7
WP_000176303.1\|108893_109499_-	DUF2913 family protein	NA	NA	NA	NA
WP_001527010.1\|109555_109891_-	hypothetical protein	NA	NA	NA	NA
WP_001541564.1\|110074_110491_-	hypothetical protein	O64348	Escherichia_phage	8.2e-07	42.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP012396

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012396_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012396_1

940959-941598

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAAC	CRT

10 spacers

cas3,cas8e,cse2gr11,cas7

The CRISPR arrays of NZ_CP012396_1

>merge|NZ_CP012396|1|940959-941598|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACTGAGGATTTCGCCGCGCTGTTGGCCTCCAGATTCGTGTTCCCCGCGCCAGCGGGGATAAACTGCCGTGCCTGTCCAGGACAAATTGCCGATTATTGTGTTCCCCGCGCCAGCGGGGATAAACTGCTGCCGGTCTGTGCTGTTGTCGTCAATAATCAGTGTTCCCCGCGCCAGCGGGGATAAACCGGCATGTGACAGTCTGATTTTTATAGCGCATGAGTGTTCCCCGCGCCAGCGGGGATAAACCCAATTTAGGGGCCGGAACTCCGGGAAAGGCAGCGTGTTCCCCGCGCCAGCGGGGATAAACCGCAAACACCAAGCTCTTCCGCCGCGCGTTCCTGAGTGTTCCCCGCGCCAGCGGGGATAAACCGTTGCTCTCATTAAAGGGGTTTCCATGTTTGATGTGTTCCCCGCGCCAGCGGGGATAAACCGCGGTCGCAGCCTGGCCTGTTGCCGTAGAATCGGTGTTCCCCTCGCCAGCGGGGATAAACCGAGTTACTGATGCAGACTGCGGATCTTAATCGGGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCGCCAACGACTGGAATTTTTGCGTGTAGCCGTGTTCCCCGCGCCAACAAGGATAGCCGT

>NZ_CP012396|1|1|940959-941537|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACTG	AGGATTTCGCCGCGCTGTTGGCCTCCAGATTC
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CCGTGCCTGTCCAGGACAAATTGCCGATTATT
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CTGCCGGTCTGTGCTGTTGTCGTCAATAATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCATGTGACAGTCTGATTTTTATAGCGCATGA
GTGTTCCCCGCGCCAGCGGGGATAAACCC	AATTTAGGGGCCGGAACTCCGGGAAAGGCAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAACACCAAGCTCTTCCGCCGCGCGTTCCTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCTCTCATTAAAGGGGTTTCCATGTTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGTCGCAGCCTGGCCTGTTGCCGTAGAATCG
GTGTTCCCCTCGCCAGCGGGGATAAACCG	AGTTACTGATGCAGACTGCGGATCTTAATCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP012396|1|1|940959-941598|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACTG	AGGATTTCGCCGCGCTGTTGGCCTCCAGATTC
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CCGTGCCTGTCCAGGACAAATTGCCGATTATT
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CTGCCGGTCTGTGCTGTTGTCGTCAATAATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCATGTGACAGTCTGATTTTTATAGCGCATGA
GTGTTCCCCGCGCCAGCGGGGATAAACCC	AATTTAGGGGCCGGAACTCCGGGAAAGGCAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAACACCAAGCTCTTCCGCCGCGCGTTCCTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCTCTCATTAAAGGGGTTTCCATGTTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGTCGCAGCCTGGCCTGTTGCCGTAGAATCG
GTGTTCCCCTCGCCAGCGGGGATAAACCG	AGTTACTGATGCAGACTGCGGATCTTAATCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCAACGACTGGAATTTTTGCGTGTAGCC
GTGTTCCCCGCGCCAACAAGGATAGCCGT

>NZ_CP012396|1|1|940959-941596|CRT
GTGTTCCCCGCGCCAGCGGGGATAAAC	TGAGGATTTCGCCGCGCTGTTGGCCTCCAGATTC
GTGTTCCCCGCGCCAGCGGGGATAAAC	TGCCGTGCCTGTCCAGGACAAATTGCCGATTATT
GTGTTCCCCGCGCCAGCGGGGATAAAC	TGCTGCCGGTCTGTGCTGTTGTCGTCAATAATCA
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGGCATGTGACAGTCTGATTTTTATAGCGCATGA
GTGTTCCCCGCGCCAGCGGGGATAAAC	CCAATTTAGGGGCCGGAACTCCGGGAAAGGCAGC
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGCAAACACCAAGCTCTTCCGCCGCGCGTTCCTGA
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGTTGCTCTCATTAAAGGGGTTTCCATGTTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGCGGTCGCAGCCTGGCCTGTTGCCGTAGAATCG
GTGTTCCCCTCGCCAGCGGGGATAAAC	CGAGTTACTGATGCAGACTGCGGATCTTAATCGG
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGTGCGCCAACGACTGGAATTTTTGCGTGTAGCC
GTGTTCCCCGCGCCAACAAGGATAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012396.1\|WP_001290670.1\|945166_946879_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP012396.1\|WP_000178270.1\|930522_931029_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
NZ_CP012396.1\|WP_001207998.1\|941696_942494_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
NZ_CP012396.1\|WP_000039870.1\|946980_947715_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP012396.1\|WP_001044459.1\|931048_931822_-\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|185177
NZ_CP012396.1\|WP_000108313.1\|942581_942944_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP012396.1\|WP_000210863.1\|936836_938474_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP012396.1\|WP_000206417.1\|953995_955054_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP012396.1\|WP_000036734.1\|938556_939855_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP012396.1\|WP_001199961.1\|939990_940662_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP012396.1\|WP_001145541.1\|947802_948756_-\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP012396.1\|WP_000029737.1\|949199_951863_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP012396.1\|WP_000210451.1\|935808_936609_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP012396.1\|WP_000832393.1\|930037_930508_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
NZ_CP012396.1\|WP_001079646.1\|929504_930041_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185168
NZ_CP012396.1\|WP_000210932.1\|943367_945167_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP012396.1\|WP_000368579.1\|951874_953431_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP012396.1\|WP_000981797.1\|931834_934534_-\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|185176
NZ_CP012396.1\|WP_000117945.1\|953427_953982_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP012396.1\|WP_000842512.1\|934613_935201_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185169

Protein	Function_ID	Function_description	E-value
NZ_CP012396.1\|WP_001290670.1\|945166_946879_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP012396.1\|WP_000178270.1\|930522_931029_-\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	4.31975e-105
NZ_CP012396.1\|WP_001207998.1\|941696_942494_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.00381e-102
NZ_CP012396.1\|WP_000039870.1\|946980_947715_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.73232e-139
NZ_CP012396.1\|WP_001044459.1\|931048_931822_-\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
NZ_CP012396.1\|WP_000108313.1\|942581_942944_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NZ_CP012396.1\|WP_000210863.1\|936836_938474_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP012396.1\|WP_000206417.1\|953995_955054_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.28543e-133
NZ_CP012396.1\|WP_000036734.1\|938556_939855_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP012396.1\|WP_001199961.1\|939990_940662_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
NZ_CP012396.1\|WP_001145541.1\|947802_948756_-\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP012396.1\|WP_000029737.1\|949199_951863_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP012396.1\|WP_000210451.1\|935808_936609_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
NZ_CP012396.1\|WP_000832393.1\|930037_930508_-\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	2.10162e-98
NZ_CP012396.1\|WP_001079646.1\|929504_930041_-\|fimbrial-protein	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	7.785e-121
NZ_CP012396.1\|WP_000210932.1\|943367_945167_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP012396.1\|WP_000368579.1\|951874_953431_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP012396.1\|WP_000981797.1\|931834_934534_-\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|185176	PRK15273, PRK15273, fimbrial biogenesis outer membrane usher protein.	0
NZ_CP012396.1\|WP_000117945.1\|953427_953982_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
NZ_CP012396.1\|WP_000842512.1\|934613_935201_-\|fimbrial-protein	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	5.36845e-100

>NZ_CP012396.1|WP_001199961.1|939990_940662_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP012396.1|WP_000036734.1|938556_939855_+|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP012396.1|WP_000210863.1|936836_938474_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>NZ_CP012396.1|WP_000210451.1|935808_936609_+|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NZ_CP012396.1|WP_000842512.1|934613_935201_-|fimbrial-protein
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>NZ_CP012396.1|WP_000981797.1|931834_934534_-|fimbrial-biogenesis-outer-membrane-usher-protein
MMNNTWKSVLCPIACGVGMLLSLSPYSASGKDIEFNTDFLDVKNRDNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVTQLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDWDPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQASYDHRDDDENTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVVSDDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTLHVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASWGVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQGNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVTYNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYNGDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQGAQADGYYSHQGALTDIDLSADYEEGSYRSLGMSLRGGMTLTTQGGALHRGSLAGSTRLLVDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWLAGVKAGETLKVFWDGAAQCEASLPSTFTPELLANALLLPCKMLEGQPPTAPQKSSPLPAQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME
>NZ_CP012396.1|WP_001044459.1|931048_931822_-|fimbria/pilus-periplasmic-chaperone
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>NZ_CP012396.1|WP_000178270.1|930522_931029_-|fimbrial-protein
MTMLTRWKMLVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCTVGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>NZ_CP012396.1|WP_000832393.1|930037_930508_-|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGEMLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTSVPELGIELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>NZ_CP012396.1|WP_001079646.1|929504_930041_-|fimbrial-protein
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFSGSATVSFEYQ
>NZ_CP012396.1|WP_001207998.1|941696_942494_+|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGKNFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NZ_CP012396.1|WP_000108313.1|942581_942944_-|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NZ_CP012396.1|WP_000210932.1|943367_945167_+|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGVVAVTPVPERKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIDLAWSRDQKEKIYVQDKLREQGAELWCWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NZ_CP012396.1|WP_001290670.1|945166_946879_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVAITDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP012396.1|WP_000039870.1|946980_947715_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP012396.1|WP_001145541.1|947802_948756_-|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP012396.1|WP_000029737.1|949199_951863_+|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NZ_CP012396.1|WP_000368579.1|951874_953431_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP012396.1|WP_000117945.1|953427_953982_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>NZ_CP012396.1|WP_000206417.1|953995_955054_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITALHENMNEVYAQETAFKNFNVMNQQGSMKDVLDFICA

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Crispr_ID: NZ_CP012396_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012396_2

957750-958266

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

8 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP012396_2

>merge|NZ_CP012396|2|957750-958266|CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGACGTTGGCTGAAAACGGTTTTTCGGTCCGCCTGTGTTCCCCGCGCCAGCGGGGATAAACCGAATATATGGCGCTCACGCGCATGAGCATTCTCGTGTTCCCCGCGCCAGCGGGGATAAACCGCAGGGCAAATTCATCCGCCGCTGACCACTGGTGTGTTCCCCGCGCCAGCGGGGATAAACCGGACGCTTACATCTCACCGAGAGATTTTGAGGCGTGTTCCCCGCGCCAGCGGGGATAAACCGGGAACTGGTTTAGCTATCGCTGCCGGGGCTATGTGTTCCCCGCGCCAGCGGGGATAAACCGGATTGCTCAGATTGGGAATTTGACCAGCGGCCGTGTTCCCCGCGCCAGCGGGGATAAACCGTCACGAGGGCCCCCTTATTGGGTCGGGCAGGTGTGTTCCCCGCGCCAGCGGGGATAAACCGGTTGGGTTGCATAGATGACACGCTTATAAATAGTGTTCCCCGCGTCAGCGGGGATAAACAC

>NZ_CP012396|2|2|957750-958266|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGTTGGCTGAAAACGGTTTTTCGGTCCGCCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATATATGGCGCTCACGCGCATGAGCATTCTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGGCAAATTCATCCGCCGCTGACCACTGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCTTACATCTCACCGAGAGATTTTGAGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAACTGGTTTAGCTATCGCTGCCGGGGCTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATTGCTCAGATTGGGAATTTGACCAGCGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACGAGGGCCCCCTTATTGGGTCGGGCAGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTGGGTTGCATAGATGACACGCTTATAAATA
GTGTTCCCCGCGTCAGCGGGGATAAACAC

>NZ_CP012396|2|2|957750-958266|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGTTGGCTGAAAACGGTTTTTCGGTCCGCCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATATATGGCGCTCACGCGCATGAGCATTCTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGGCAAATTCATCCGCCGCTGACCACTGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCTTACATCTCACCGAGAGATTTTGAGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAACTGGTTTAGCTATCGCTGCCGGGGCTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATTGCTCAGATTGGGAATTTGACCAGCGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACGAGGGCCCCCTTATTGGGTCGGGCAGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTGGGTTGCATAGATGACACGCTTATAAATA
GTGTTCCCCGCGTCAGCGGGGATAAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012396.1\|WP_001221538.1\|965637_966399_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP012396.1\|WP_001145541.1\|947802_948756_-\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP012396.1\|WP_001092251.1\|960495_961935_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP012396.1\|WP_000134246.1\|964607_965657_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP012396.1\|WP_000490481.1\|958280_959327_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP012396.1\|WP_000039870.1\|946980_947715_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP012396.1\|WP_001518648.1\|957359_957653_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP012396.1\|WP_000741653.1\|963421_964132_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP012396.1\|WP_000206417.1\|953995_955054_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP012396.1\|WP_001219253.1\|964131_964611_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP012396.1\|WP_000085115.1\|955064_955811_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP012396.1\|WP_000281483.1\|955792_956443_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP012396.1\|WP_000117945.1\|953427_953982_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP012396.1\|WP_000029737.1\|949199_951863_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP012396.1\|WP_000368579.1\|951874_953431_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP012396.1\|WP_001118109.1\|962544_962901_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP012396.1\|WP_001173663.1\|961921_962527_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP012396.1\|WP_000144830.1\|956439_957360_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP012396.1\|WP_000372384.1\|959577_960486_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP012396.1\|WP_000517480.1\|963091_963403_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156

Protein	Function_ID	Function_description	E-value
NZ_CP012396.1\|WP_001221538.1\|965637_966399_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
NZ_CP012396.1\|WP_001145541.1\|947802_948756_-\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP012396.1\|WP_001092251.1\|960495_961935_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP012396.1\|WP_000134246.1\|964607_965657_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP012396.1\|WP_000490481.1\|958280_959327_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP012396.1\|WP_000039870.1\|946980_947715_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.73232e-139
NZ_CP012396.1\|WP_001518648.1\|957359_957653_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62
NZ_CP012396.1\|WP_000741653.1\|963421_964132_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.09575e-119
NZ_CP012396.1\|WP_000206417.1\|953995_955054_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.28543e-133
NZ_CP012396.1\|WP_001219253.1\|964131_964611_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	3.84083e-103
NZ_CP012396.1\|WP_000085115.1\|955064_955811_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.23137e-48
NZ_CP012396.1\|WP_000281483.1\|955792_956443_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	7.7595e-75
NZ_CP012396.1\|WP_000117945.1\|953427_953982_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
NZ_CP012396.1\|WP_000029737.1\|949199_951863_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP012396.1\|WP_000368579.1\|951874_953431_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP012396.1\|WP_001118109.1\|962544_962901_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	4.85353e-49
NZ_CP012396.1\|WP_001173663.1\|961921_962527_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	4.61291e-146
NZ_CP012396.1\|WP_000144830.1\|956439_957360_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.63116e-157
NZ_CP012396.1\|WP_000372384.1\|959577_960486_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP012396.1\|WP_000517480.1\|963091_963403_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64

>NZ_CP012396.1|WP_001518648.1|957359_957653_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>NZ_CP012396.1|WP_000144830.1|956439_957360_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPESLGDSGHRGHG
>NZ_CP012396.1|WP_000281483.1|955792_956443_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASTIFDVQTRPFAPMLSAGQTLRFNLRANPTICKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALEWLARQGEQNGFTLREASVDAYRQQQIRREKSRQMIQFSSVDYTGVLVINEPALFLQRLAQGYGKSRAFGCGMMMIKPGDDA
>NZ_CP012396.1|WP_000085115.1|955064_955811_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNTFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGNAADVLREAYRWYQDQFNALKLTLPGLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NZ_CP012396.1|WP_000206417.1|953995_955054_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITALHENMNEVYAQETAFKNFNVMNQQGSMKDVLDFICA
>NZ_CP012396.1|WP_000117945.1|953427_953982_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>NZ_CP012396.1|WP_000368579.1|951874_953431_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP012396.1|WP_000029737.1|949199_951863_+|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NZ_CP012396.1|WP_001145541.1|947802_948756_-|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP012396.1|WP_000039870.1|946980_947715_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP012396.1|WP_000490481.1|958280_959327_-|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NZ_CP012396.1|WP_000372384.1|959577_960486_+|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NZ_CP012396.1|WP_001092251.1|960495_961935_+|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYCEETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NZ_CP012396.1|WP_001173663.1|961921_962527_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NZ_CP012396.1|WP_001118109.1|962544_962901_+|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>NZ_CP012396.1|WP_000517480.1|963091_963403_+|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NZ_CP012396.1|WP_000741653.1|963421_964132_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLTISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NZ_CP012396.1|WP_001219253.1|964131_964611_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NZ_CP012396.1|WP_000134246.1|964607_965657_+|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NZ_CP012396.1|WP_001221538.1|965637_966399_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012396_1	1.6\|941293\|33\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941293-941325	33	NZ_CP032236	Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence	63403-63435	4	0.879
NZ_CP012396_1	1.6\|941293\|33\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941293-941325	33	NZ_LN681230	Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence	91355-91387	4	0.879
NZ_CP012396_1	1.15\|941230\|34\|NZ_CP012396\|CRT	941230-941263	34	NZ_CP044178	Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1	18967-19000	5	0.853
NZ_CP012396_1	1.15\|941230\|34\|NZ_CP012396\|CRT	941230-941263	34	CP053324	Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence	25136-25169	5	0.853
NZ_CP012396_1	1.16\|941291\|35\|NZ_CP012396\|CRT	941291-941325	35	NZ_CP032236	Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence	63403-63437	5	0.857
NZ_CP012396_1	1.16\|941291\|35\|NZ_CP012396\|CRT	941291-941325	35	NZ_LN681230	Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence	91353-91387	5	0.857
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP044178	Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1	18969-19000	6	0.812
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	CP053324	Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence	25138-25169	6	0.812
NZ_CP012396_1	1.15\|941230\|34\|NZ_CP012396\|CRT	941230-941263	34	NZ_LN890526	Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence	31716-31749	6	0.824
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_LN890526	Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence	31718-31749	7	0.781
NZ_CP012396_1	1.3\|941110\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941110-941141	32	MG592432	Vibrio phage 1.050.O._10N.286.48.A6, partial genome	21687-21718	8	0.75
NZ_CP012396_1	1.3\|941110\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941110-941141	32	MG592431	Vibrio phage 1.049.O._10N.286.54.B5, partial genome	21426-21457	8	0.75
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP053022	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence	329022-329053	8	0.75
NZ_CP012396_1	1.8\|941416\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941416-941447	32	MN694003	Marine virus AFVG_250M677, complete genome	17629-17660	8	0.75
NZ_CP012396_1	1.18\|941414\|34\|NZ_CP012396\|CRT	941414-941447	34	MN694003	Marine virus AFVG_250M677, complete genome	17627-17660	8	0.765
NZ_CP012396_1	1.1\|940988\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	940988-941019	32	CP006879	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence	405613-405644	9	0.719
NZ_CP012396_1	1.3\|941110\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941110-941141	32	NC_047790	Pseudoalteromonas phage C5a, complete genome	34441-34472	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP048340	Escherichia coli strain 142 plasmid p142_C, complete sequence	2410-2441	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_LR130559	Escherichia coli strain MS14385 isolate MS14385 plasmid 5	41882-41913	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP020518	Escherichia coli strain 222 plasmid unnamed2, complete sequence	13450-13481	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP020497	Escherichia coli strain 103 plasmid unnamed2, complete sequence	37140-37171	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP040921	Escherichia coli strain FC853_EC plasmid p853EC2, complete sequence	32060-32091	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	CP053252	Escherichia coli strain SCU-204 plasmid pSCU-204-5, complete sequence	19381-19412	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP042622	Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-7, complete sequence	2614-2645	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_LT985302	Escherichia coli strain ECOR 39 genome assembly, plasmid: RCS82_pI	11943-11974	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP028194	Escherichia coli strain CFSAN018748 plasmid pGMI14-004_3, complete sequence	15383-15414	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP024865	Escherichia coli strain AR_0015 plasmid unitig_3_pilon, complete sequence	22646-22677	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	AP019710	Escherichia coli O145:H28 122715 plasmid pO145_122715_2 DNA, complete genome	4361-4392	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP024829	Escherichia coli strain CREC-544 plasmid pCREC-544_3, complete sequence	2221-2252	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP009861	Escherichia coli strain ECONIH1 plasmid pECO-b75, complete sequence	2868-2899	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	CP025877	Escherichia coli strain 503458 plasmid p503458_49, complete sequence	18343-18374	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP023368	Escherichia coli strain 1428 plasmid p48, complete sequence	4914-4945	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP032259	Escherichia coli strain AR_0067 plasmid unnamed2, complete sequence	23402-23433	9	0.719
NZ_CP012396_1	1.5\|941232\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941232-941263	32	NZ_CP037450	Escherichia coli strain ATCC 25922 plasmid unnamed, complete sequence	15851-15882	9	0.719
NZ_CP012396_1	1.6\|941293\|33\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941293-941325	33	NZ_CP031947	Ruegeria sp. AD91A plasmid unnamed1, complete sequence	143751-143783	9	0.727
NZ_CP012396_2	2.2\|957840\|32\|NZ_CP012396\|CRISPRCasFinder,CRT	957840-957871	32	KY006853	Erythrobacter phage vB_EliS_R6L, complete genome	41418-41449	9	0.719
NZ_CP012396_2	2.6\|958084\|32\|NZ_CP012396\|CRISPRCasFinder,CRT	958084-958115	32	MK449011	Streptococcus phage Javan92, complete genome	36157-36188	9	0.719
NZ_CP012396_2	2.6\|958084\|32\|NZ_CP012396\|CRISPRCasFinder,CRT	958084-958115	32	MK448835	Streptococcus phage Javan93, complete genome	36157-36188	9	0.719
NZ_CP012396_2	2.6\|958084\|32\|NZ_CP012396\|CRISPRCasFinder,CRT	958084-958115	32	MK448836	Streptococcus phage Javan95, complete genome	37400-37431	9	0.719
NZ_CP012396_2	2.6\|958084\|32\|NZ_CP012396\|CRISPRCasFinder,CRT	958084-958115	32	MK448825	Streptococcus phage Javan639, complete genome	37400-37431	9	0.719
NZ_CP012396_2	2.8\|958206\|32\|NZ_CP012396\|CRISPRCasFinder,CRT	958206-958237	32	NZ_MG266000	Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence	5501-5532	9	0.719
NZ_CP012396_1	1.1\|940988\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	940988-941019	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	699963-699994	10	0.688
NZ_CP012396_1	1.7\|941355\|32\|NZ_CP012396\|PILER-CR,CRISPRCasFinder	941355-941386	32	NZ_LR134399	Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence	103231-103262	10	0.688
NZ_CP012396_1	1.16\|941291\|35\|NZ_CP012396\|CRT	941291-941325	35	NZ_CP031947	Ruegeria sp. AD91A plasmid unnamed1, complete sequence	143751-143785	11	0.686

1. spacer 1.6|941293|33|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP032236 (Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence) position: , mismatch: 4, identity: 0.879

caaacaccaagctcttccgccgcgcgttcctga	CRISPR spacer
catttaccaagctcttccgctgcgcgttcctga	Protospacer
**  .***************.************

2. spacer 1.6|941293|33|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_LN681230 (Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence) position: , mismatch: 4, identity: 0.879

caaacaccaagctcttccgccgcgcgttcctga	CRISPR spacer
catttaccaagctcttccgctgcgcgttcctga	Protospacer
**  .***************.************

3. spacer 1.15|941230|34|NZ_CP012396|CRT matches to NZ_CP044178 (Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1) position: , mismatch: 5, identity: 0.853

ccaattt----aggggccggaactccgggaaaggcagc	CRISPR spacer
----tttgagaaggggccggaactccgggaaaggcacc	Protospacer
    ***    ************************* *

4. spacer 1.15|941230|34|NZ_CP012396|CRT matches to CP053324 (Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.853

ccaattt----aggggccggaactccgggaaaggcagc	CRISPR spacer
----tttgagaaggggccggaactccgggaaaggcacc	Protospacer
    ***    ************************* *

5. spacer 1.16|941291|35|NZ_CP012396|CRT matches to NZ_CP032236 (Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence) position: , mismatch: 5, identity: 0.857

cgcaaacaccaagctcttccgccgcgcgttcctga	CRISPR spacer
ggcatttaccaagctcttccgctgcgcgttcctga	Protospacer
 ***  .***************.************

6. spacer 1.16|941291|35|NZ_CP012396|CRT matches to NZ_LN681230 (Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence) position: , mismatch: 5, identity: 0.857

cgcaaacaccaagctcttccgccgcgcgttcctga	CRISPR spacer
ggcatttaccaagctcttccgctgcgcgttcctga	Protospacer
 ***  .***************.************

7. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP044178 (Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1) position: , mismatch: 6, identity: 0.812

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccgggaaaggcacc	Protospacer
 .   ************************* *

8. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to CP053324 (Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccgggaaaggcacc	Protospacer
 .   ************************* *

9. spacer 1.15|941230|34|NZ_CP012396|CRT matches to NZ_LN890526 (Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence) position: , mismatch: 6, identity: 0.824

ccaattt----aggggccggaactccgggaaaggcagc	CRISPR spacer
----tttgagaaggggccggaactccggaaaaggcacc	Protospacer
    ***    *****************.******* *

10. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_LN890526 (Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence) position: , mismatch: 7, identity: 0.781

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggaaaaggcacc	Protospacer
 .   *****************.******* *

11. spacer 1.3|941110|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to MG592432 (Vibrio phage 1.050.O._10N.286.48.A6, partial genome) position: , mismatch: 8, identity: 0.75

ctgccggtctgtgctgttgtcgtcaataatca	CRISPR spacer
aatctgctctgtgctgttgtagtcaattataa	Protospacer
   *.* ************* ****** ** *

12. spacer 1.3|941110|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to MG592431 (Vibrio phage 1.049.O._10N.286.54.B5, partial genome) position: , mismatch: 8, identity: 0.75

ctgccggtctgtgctgttgtcgtcaataatca	CRISPR spacer
aatctgctctgtgctgttgtagtcaattataa	Protospacer
   *.* ************* ****** ** *

13. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP053022 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence) position: , mismatch: 8, identity: 0.75

---aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
gtcagtt---gggccggaaagccgggaaaggcata	Protospacer
   *.**   *********  ************

14. spacer 1.8|941416|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to MN694003 (Marine virus AFVG_250M677, complete genome) position: , mismatch: 8, identity: 0.75

cggtcgcagcctggcctgttgccgtagaatcg	CRISPR spacer
cgatcgcagcctgggctgttgccgtgctcgcc	Protospacer
**.*********** **********.    *

15. spacer 1.18|941414|34|NZ_CP012396|CRT matches to MN694003 (Marine virus AFVG_250M677, complete genome) position: , mismatch: 8, identity: 0.765

cgcggtcgcagcctggcctgttgccgtagaatcg	CRISPR spacer
cgcgatcgcagcctgggctgttgccgtgctcgcc	Protospacer
****.*********** **********.    *

16. spacer 1.1|940988|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to CP006879 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence) position: , mismatch: 9, identity: 0.719

aggatttcgccgcgctgttggcctccagattc	CRISPR spacer
cagggtcgaccgcgctgtcgccctccagattc	Protospacer
 .*. *. .*********.* ***********

17. spacer 1.3|941110|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NC_047790 (Pseudoalteromonas phage C5a, complete genome) position: , mismatch: 9, identity: 0.719

ctgccggtctgtgctgttgtcgtcaataatca	CRISPR spacer
tttggtgtctgtgccgttttcgtcaataagct	Protospacer
.*    ********.*** ********** *

18. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP048340 (Escherichia coli strain 142 plasmid p142_C, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

19. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_LR130559 (Escherichia coli strain MS14385 isolate MS14385 plasmid 5) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

20. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP020518 (Escherichia coli strain 222 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

21. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP020497 (Escherichia coli strain 103 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

22. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP040921 (Escherichia coli strain FC853_EC plasmid p853EC2, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

23. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to CP053252 (Escherichia coli strain SCU-204 plasmid pSCU-204-5, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

24. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP042622 (Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-7, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

25. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_LT985302 (Escherichia coli strain ECOR 39 genome assembly, plasmid: RCS82_pI) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

26. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP028194 (Escherichia coli strain CFSAN018748 plasmid pGMI14-004_3, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

27. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP024865 (Escherichia coli strain AR_0015 plasmid unitig_3_pilon, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

28. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to AP019710 (Escherichia coli O145:H28 122715 plasmid pO145_122715_2 DNA, complete genome) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

29. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP024829 (Escherichia coli strain CREC-544 plasmid pCREC-544_3, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

30. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP009861 (Escherichia coli strain ECONIH1 plasmid pECO-b75, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

31. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to CP025877 (Escherichia coli strain 503458 plasmid p503458_49, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

32. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP023368 (Escherichia coli strain 1428 plasmid p48, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

33. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP032259 (Escherichia coli strain AR_0067 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

34. spacer 1.5|941232|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP037450 (Escherichia coli strain ATCC 25922 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

aatttaggggccggaactccgggaaaggcagc	CRISPR spacer
tgagaaggggccggaactccggtaaagggcac	Protospacer
 .   ***************** *****  .*

35. spacer 1.6|941293|33|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP031947 (Ruegeria sp. AD91A plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

caaacaccaagctcttccgccgcgcgttcctga	CRISPR spacer
gaaacaccaaggtcttccgccgcacgggcaaag	Protospacer
 ********** ***********.**  *  ..

36. spacer 2.2|957840|32|NZ_CP012396|CRISPRCasFinder,CRT matches to KY006853 (Erythrobacter phage vB_EliS_R6L, complete genome) position: , mismatch: 9, identity: 0.719

aatatatggcgctcacgcgcatgagcattctc	CRISPR spacer
acgcaatggcgctgacgcgcatgatcatttcg	Protospacer
*    ******** ********** ****..

37. spacer 2.6|958084|32|NZ_CP012396|CRISPRCasFinder,CRT matches to MK449011 (Streptococcus phage Javan92, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

38. spacer 2.6|958084|32|NZ_CP012396|CRISPRCasFinder,CRT matches to MK448835 (Streptococcus phage Javan93, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

39. spacer 2.6|958084|32|NZ_CP012396|CRISPRCasFinder,CRT matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

40. spacer 2.6|958084|32|NZ_CP012396|CRISPRCasFinder,CRT matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

41. spacer 2.8|958206|32|NZ_CP012396|CRISPRCasFinder,CRT matches to NZ_MG266000 (Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence) position: , mismatch: 9, identity: 0.719

gttgggttgcatagatgacacgcttataaata	CRISPR spacer
gaattatggcatagatgacatgattataaatt	Protospacer
*    .* ************.* ********

42. spacer 1.1|940988|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

aggatttcgccgcgctgttggcctccagattc	CRISPR spacer
gggatatcgccgcgctgatggcctatgaccac	Protospacer
.**** *********** ****** ... . *

43. spacer 1.7|941355|32|NZ_CP012396|PILER-CR,CRISPRCasFinder matches to NZ_LR134399 (Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.688

ttgctctcattaaaggggtttccatgtttgat	CRISPR spacer
gattcgtcattacagtggtttccatgttttag	Protospacer
   .. ****** ** ************* *

44. spacer 1.16|941291|35|NZ_CP012396|CRT matches to NZ_CP031947 (Ruegeria sp. AD91A plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.686

cgcaaacaccaagctcttccgccgcgcgttcctga	CRISPR spacer
gagaaacaccaaggtcttccgccgcacgggcaaag	Protospacer
 . ********** ***********.**  *  ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1414852 : 1420905

Salmonella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_105789229.1\|1414852_1415020_+	hypothetical protein	A0A1R3Y5S2	Salmonella_virus	1.3e-11	63.5
WP_105789228.1\|1415035_1415179_+	hypothetical protein	A0A1R3Y5S2	Salmonella_virus	1.7e-12	82.9
WP_000400616.1\|1416168_1418091_-	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	5.6e-300	77.3
WP_000703599.1\|1418108_1418363_-	glycosyltransferase	A8CG95	Salmonella_phage	3.1e-25	79.5
WP_001576268.1\|1418331_1418721_-	GtrA family protein	A0A192Y6N5	Salmonella_phage	1.1e-50	85.6
WP_000377779.1\|1419963_1420905_-	membrane protein	E7DYY8	Enterobacteria_phage	1.6e-146	87.8

DBSCAN-SWA_2

1657338 : 1666509

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569168.1\|1657338_1658286_+	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	2.8e-10	27.8
WP_000824854.1\|1658269_1659001_+	ABC transporter permease	NA	NA	NA	NA
WP_001261696.1\|1658981_1659089_-	protein YohO	NA	NA	NA	NA
WP_001240420.1\|1659148_1659880_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.5e-99	86.9
WP_000272845.1\|1660102_1661788_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	6.2e-279	91.1
WP_000598637.1\|1661784_1662504_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000950414.1\|1662550_1663018_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	4.3e-73	89.7
WP_001197951.1\|1663074_1663605_-	YehR family lipoprotein	NA	NA	NA	NA
WP_000703145.1\|1663776_1664235_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	6.4e-53	72.5
WP_000195340.1\|1664475_1666509_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	6.1e-55	26.9

DBSCAN-SWA_3

1733707 : 1744214

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001144948.1\|1733707_1735111_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	4.0e-21	26.5
WP_000981469.1\|1735288_1736182_+	GalU regulator GalF	A0A127AW70	Bacillus_phage	4.8e-44	42.2
WP_000697846.1\|1736558_1737644_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.6e-102	53.9
WP_001023658.1\|1737643_1738543_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.1e-30	36.0
WP_000857535.1\|1738590_1739469_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.1e-108	65.5
WP_000973709.1\|1739469_1740021_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.3e-52	58.0
WP_066038535.1\|1740026_1741001_+	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_000648783.1\|1741016_1741790_+	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_000565913.1\|1741794_1742874_+	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.7e-16	24.5
WP_000126349.1\|1742900_1744214_+	lipopolysaccharide biosynthesis protein RfbH	H8ZJ36	Ostreococcus_tauri_virus	7.0e-52	35.1

DBSCAN-SWA_4

1857137 : 1904633

Salmonella_phage(77.78%)

holin,portal,integrase,head,capsid,tail,plate,transposase,terminase,protease

attL 1860038:1860052|attR 1908228:1908242

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001680077.1\|1857137_1858412_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	2.4e-73	39.9
WP_001675175.1\|1859075_1859366_-	DUF4102 domain-containing protein	H2BDA3	Pseudomonas_phage	1.2e-07	49.1
WP_000598920.1\|1859737_1860535_-	DgsA anti-repressor MtfA	NA	NA	NA	NA
1860038:1860052	attL	NA	NA	NA	NA
WP_000532847.1\|1860826_1861816_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	8.6e-196	100.0
WP_000414876.1\|1861817_1862060_-	DUF4224 domain-containing protein	Q8HAA9	Salmonella_phage	9.5e-40	100.0
WP_001061370.1\|1862084_1862654_-	3'-5' exoribonuclease	A0A192Y6E0	Salmonella_phage	9.3e-110	99.5
WP_000208076.1\|1862650_1863514_-	DUF551 domain-containing protein	S4TSR6	Salmonella_phage	5.2e-64	49.2
WP_000267991.1\|1863510_1863804_-	hypothetical protein	A0A1V0E5L2	Salmonella_phage	1.5e-50	100.0
WP_000065085.1\|1864075_1864435_-	Eaf protein	T1SA95	Salmonella_phage	1.0e-58	89.9
WP_000071068.1\|1864431_1864947_-	DUF262 domain-containing protein	A0A2H4FWH2	Salmonella_phage	1.3e-94	96.5
WP_000764235.1\|1864943_1865174_-	hypothetical protein	Q8HAA4	Salmonella_phage	2.0e-34	100.0
WP_000008351.1\|1865244_1865784_-	hypothetical protein	A0A192Y8M4	Salmonella_phage	2.6e-98	100.0
WP_000551790.1\|1865878_1866796_-	recombination-associated protein RdgC	S4TWL4	Salmonella_phage	1.3e-97	59.7
WP_000078504.1\|1867365_1867617_+	hypothetical protein	NA	NA	NA	NA
WP_001067433.1\|1867692_1867878_-	hypothetical protein	A0A1C9II97	Salmonella_phage	1.2e-13	73.3
WP_001020644.1\|1868083_1868779_-	helix-turn-helix transcriptional regulator	Q8HAA0	Salmonella_phage	2.7e-127	99.6
WP_001191666.1\|1868876_1869101_+	helix-turn-helix transcriptional regulator	A0A1C9IHV8	Salmonella_phage	1.9e-34	100.0
WP_000509728.1\|1869129_1869684_+	hypothetical protein	A0A1C9II13	Salmonella_phage	3.4e-101	98.9
WP_001087406.1\|1869680_1870838_+	peptidase	Q8HA97	Salmonella_phage	2.8e-214	98.4
WP_000620702.1\|1870834_1871059_+	hypothetical protein	A0A1C9II64	Salmonella_phage	3.3e-39	100.0
WP_000096529.1\|1871055_1872030_+	hypothetical protein	A0A1C9IHW0	Salmonella_phage	1.2e-165	97.8
WP_000054227.1\|1872026_1872500_+	PerC family transcriptional regulator	A0A1C9IHW0	Salmonella_phage	3.9e-53	94.6
WP_000200166.1\|1872496_1873378_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1C9II58	Salmonella_phage	8.3e-166	96.2
WP_000779149.1\|1873386_1873776_+	RusA family crossover junction endodeoxyribonuclease	A0A1C9IIA0	Salmonella_phage	1.9e-69	99.2
WP_001061459.1\|1873792_1874653_+	KilA-N domain-containing protein	A0A192Y6F8	Salmonella_phage	1.5e-159	98.3
WP_012543375.1\|1874660_1875650_+	DUF968 domain-containing protein	A0A1C9IHZ5	Salmonella_phage	1.9e-190	97.6
WP_001047141.1\|1875663_1876416_+	antitermination protein	A0A192Y5X6	Salmonella_phage	1.9e-134	92.0
WP_000357930.1\|1876465_1877539_+	hypothetical protein	NA	NA	NA	NA
WP_000765639.1\|1877551_1878124_+	hypothetical protein	NA	NA	NA	NA
WP_001294874.1\|1878212_1878602_+	membrane protein	K7PHB9	Enterobacterial_phage	1.8e-40	71.0
WP_000226304.1\|1878588_1878870_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	3.3e-36	80.6
WP_001075993.1\|1878869_1879487_+	glycoside hydrolase family 19 protein	Q8HA86	Salmonella_phage	3.2e-92	78.9
WP_000127618.1\|1879483_1880023_+	DUF2514 domain-containing protein	A0A0A0P0G7	Enterobacteria_phage	5.3e-06	37.2
WP_001135228.1\|1880046_1880397_+	HNH endonuclease	M1FQV2	Enterobacteria_phage	3.1e-63	95.7
WP_000501481.1\|1880543_1880981_+\|terminase	phage terminase small subunit P27 family	A0A1J0GV10	Halomonas_phage	1.6e-32	63.7
WP_000257219.1\|1880980_1882711_+\|terminase	terminase large subunit	Q8W631	Enterobacteria_phage	3.2e-198	58.9
WP_077905357.1\|1882982_1884077_+\|portal	phage portal protein	A0A1W6JP33	Morganella_phage	7.3e-180	82.7
WP_000003793.1\|1884069_1884672_+\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	2.0e-99	91.5
WP_000766103.1\|1884681_1885911_+\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	1.8e-206	90.9
WP_000927251.1\|1885990_1886314_+\|head,tail	phage gp6-like head-tail connector protein	Q8SBH7	Shigella_phage	2.6e-40	72.0
WP_000776844.1\|1886310_1886715_+\|head	phage head closure protein	A0A192Y6C2	Salmonella_phage	1.5e-69	96.3
WP_001135695.1\|1886686_1887199_+	hypothetical protein	Q8HAC8	Salmonella_phage	1.4e-85	93.5
WP_000779215.1\|1887195_1887756_+	hypothetical protein	A0A192Y5U4	Salmonella_phage	3.0e-105	99.5
WP_000497739.1\|1887759_1887924_+	DUF2635 domain-containing protein	Q8HAC6	Salmonella_phage	1.0e-24	100.0
WP_001007993.1\|1887913_1889410_+\|tail	tail sheath protein	Q8HAC5	Salmonella_phage	3.0e-277	99.2
WP_000515952.1\|1889409_1889766_+\|tail	tail protein	A0A192Y8K0	Salmonella_phage	2.6e-62	100.0
WP_000588852.1\|1889762_1890089_+\|tail	phage tail assembly protein	Q8HAC3	Salmonella_phage	2.3e-52	99.1
WP_000785387.1\|1890173_1892102_+\|tail	phage tail tape measure protein	Q8HAC2	Salmonella_phage	0.0e+00	99.5
WP_000863817.1\|1892135_1893476_+	DNA circularization protein	A0A192Y5U9	Salmonella_phage	1.1e-249	99.1
WP_001066630.1\|1893472_1894531_+\|plate	baseplate protein	A0A192Y7L7	Salmonella_phage	1.3e-202	100.0
WP_001273650.1\|1894530_1895064_+\|plate	phage baseplate assembly protein	Q8HAB9	Salmonella_phage	2.1e-95	99.4
WP_000605050.1\|1895068_1895482_+	hypothetical protein	Q8HAB8	Salmonella_phage	1.1e-75	100.0
WP_001699732.1\|1895474_1896554_+\|plate	baseplate J/gp47 family protein	A0A192Y6E4	Salmonella_phage	5.5e-204	99.4
WP_001207832.1\|1896556_1897144_+	DUF2313 domain-containing protein	A0A192Y5V3	Salmonella_phage	2.9e-114	100.0
WP_000554738.1\|1897130_1898693_+	hypothetical protein	Q8HAB4	Salmonella_phage	9.8e-287	99.8
WP_015701331.1\|1898662_1899262_+\|tail	tail fiber assembly protein	Q8HAB3	Salmonella_phage	5.9e-107	100.0
WP_000492926.1\|1899546_1900554_-	type III secretion system effector arginine glycosyltransferase	Q8HAB2	Salmonella_phage	7.9e-197	100.0
WP_001526483.1\|1900766_1900988_+	helix-turn-helix domain-containing protein	Q8HAB1	Salmonella_phage	1.2e-36	100.0
WP_001176778.1\|1902330_1903149_+	hypothetical protein	NA	NA	NA	NA
WP_001028172.1\|1903610_1904633_+\|transposase	IS110-like element ISSaen1 family transposase	NA	NA	NA	NA
1908228:1908242	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2436819 : 2452763

Escherichia_phage(62.5%)

holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001082296.1\|2436819_2437254_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	9.4e-30	52.1
WP_000159240.1\|2437303_2437642_-	EamA family transporter	NA	NA	NA	NA
WP_000802786.1\|2438487_2439033_-	glycoside hydrolase family 108 protein	A0A0U2S643	Escherichia_phage	2.3e-89	83.4
WP_000445513.1\|2439029_2439311_-\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.3e-16	49.4
WP_001688615.1\|2439300_2439489_-	hypothetical protein	Q8W636	Enterobacteria_phage	9.4e-11	57.4
WP_000900605.1\|2439410_2439806_-	tellurite resistance TerB family protein	Q71TK7	Escherichia_phage	4.7e-44	88.9
WP_000640113.1\|2441976_2442513_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.4e-70	70.9
WP_000774470.1\|2442509_2442800_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	5.1e-40	76.0
WP_000940751.1\|2442799_2443399_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	5.5e-97	82.9
WP_000882662.1\|2443922_2444135_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	2.5e-28	95.7
WP_000556390.1\|2444504_2445437_+	hypothetical protein	NA	NA	NA	NA
WP_001033796.1\|2445433_2445988_+	hypothetical protein	NA	NA	NA	NA
WP_001676916.1\|2446149_2446479_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	6.5e-23	51.7
WP_001227859.1\|2446751_2447219_+	helix-turn-helix domain-containing protein	A0A0U2QW76	Escherichia_phage	1.0e-53	66.9
WP_085981757.1\|2447603_2447759_+	DUF1391 family protein	M4QQ57	Salicola_phage	2.6e-06	48.9
WP_000004762.1\|2447866_2448388_-	hypothetical protein	NA	NA	NA	NA
WP_000560208.1\|2448825_2449047_+	cell division protein FtsZ	A0A0U2RTC4	Escherichia_phage	7.9e-33	83.6
WP_000800272.1\|2449131_2449449_+	hypothetical protein	NA	NA	NA	NA
WP_001676915.1\|2449476_2450094_+	exodeoxyribonuclease	A0A088CD28	Shigella_phage	2.5e-36	41.9
WP_001156217.1\|2450410_2451346_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	7.2e-144	97.3
WP_000123686.1\|2451389_2452763_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.1e-51	32.0

DBSCAN-SWA_6

2644053 : 2693303

Enterobacteria_phage(26.09%)

lysis,holin,integrase,tail,protease

attL 2673818:2673847|attR 2693439:2693468

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000984498.1\|2644053_2644935_-\|protease	protease HtpX	NA	NA	NA	NA
WP_001091237.1\|2645128_2647177_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	8.0e-87	33.5
WP_000431401.1\|2647196_2647883_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_000145727.1\|2647980_2648565_-	GAF domain-containing protein	NA	NA	NA	NA
WP_001207294.1\|2648606_2649890_+	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_001529852.1\|2649858_2652492_+	PqiB family protein	NA	NA	NA	NA
WP_001531515.1\|2652569_2654009_+	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_024131108.1\|2654126_2654363_+	DUF1480 family protein	NA	NA	NA	NA
WP_000457838.1\|2654473_2654665_+	YebW family protein	NA	NA	NA	NA
WP_000986173.1\|2654683_2655334_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	7.2e-58	50.9
WP_001134856.1\|2655557_2655722_-	membrane protein	NA	NA	NA	NA
WP_000182071.1\|2656006_2656729_-	SPI-1 type III secretion system guanine nucleotide exchange factor SopE2	NA	NA	NA	NA
WP_000422882.1\|2657412_2657808_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	9.2e-16	32.8
WP_000030934.1\|2658137_2658614_+	hypothetical protein	NA	NA	NA	NA
WP_001025515.1\|2658986_2659406_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001576019.1\|2659778_2660048_+	hypothetical protein	B6SCX2	Bacteriophage	3.1e-07	47.9
WP_001576018.1\|2660213_2660354_+	hypothetical protein	NA	NA	NA	NA
WP_001233445.1\|2663492_2664407_+	DMT family transporter	NA	NA	NA	NA
WP_000480735.1\|2664539_2664698_+	hypothetical protein	NA	NA	NA	NA
WP_000848072.1\|2664707_2665322_+	disulfide bond formation protein B	NA	NA	NA	NA
WP_000457876.1\|2666456_2666582_-	hypothetical protein	NA	NA	NA	NA
WP_012543349.1\|2667151_2667352_+	phage encoded PagK	NA	NA	NA	NA
WP_001687735.1\|2667448_2667949_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.5e-63	77.4
WP_000348541.1\|2670053_2670545_-	DUF1441 family protein	Q9EYD0	Enterobacteria_phage	7.1e-42	56.2
WP_001576014.1\|2670599_2670788_+	hypothetical protein	NA	NA	NA	NA
WP_000789530.1\|2670852_2671020_+	lytic enzyme	NA	NA	NA	NA
WP_001050883.1\|2671276_2671810_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	5.4e-11	43.0
WP_001013467.1\|2671863_2672094_-	hypothetical protein	Q8HA86	Salmonella_phage	6.1e-28	93.7
WP_077681935.1\|2672283_2672778_+	RecE	A0A0U2I1R6	Escherichia_phage	3.7e-22	70.3
WP_000622159.1\|2673421_2673691_+\|integrase	tyrosine-type recombinase/integrase	K7PHK0	Enterobacteria_phage	2.7e-11	47.8
2673818:2673847	attL	NA	NA	NA	NA
WP_001536069.1\|2674635_2675436_+	hypothetical protein	NA	NA	NA	NA
WP_000161704.1\|2675915_2676638_+	SPI-1 type III secretion system guanine nucleotide exchange factor SopE	NA	NA	NA	NA
WP_072100756.1\|2677188_2678052_-	DUF1983 domain-containing protein	K7PKJ2	Enterobacteria_phage	9.0e-48	78.9
WP_001152416.1\|2680692_2681388_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.0e-89	66.7
WP_000877926.1\|2681477_2682011_+	superoxide dismutase [Cu-Zn]	Q9MC02	Salmonella_phage	1.8e-46	54.0
WP_001541990.1\|2682905_2683385_-\|lysis	lysis protein	Q56118	Enterobacteria_phage	1.4e-55	77.0
WP_000984586.1\|2683402_2683855_-	lysozyme	A0A0M4R365	Salmonella_phage	2.3e-79	97.3
WP_001574216.1\|2683838_2684168_-\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
WP_001574215.1\|2684443_2685130_+	PipA/GogA/GtgA family type III secretion system effector	Q9MBM0	Phage_Gifsy-2	1.8e-131	99.6
WP_000798708.1\|2685490_2685940_+	hypothetical protein	NA	NA	NA	NA
WP_001574213.1\|2686313_2686838_-	hypothetical protein	NA	NA	NA	NA
WP_001097218.1\|2686934_2687624_-	antitermination protein	I6PDF8	Cronobacter_phage	2.1e-60	54.9
WP_000784710.1\|2687753_2687981_-	DNA breaking-rejoining protein	A0A0M4RU10	Salmonella_phage	2.2e-14	66.7
WP_000940753.1\|2687977_2688577_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	4.7e-96	82.9
WP_000972675.1\|2688640_2688946_-	hypothetical protein	NA	NA	NA	NA
WP_001237395.1\|2689577_2691557_-	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	1.9e-162	46.3
WP_001575998.1\|2691970_2692249_+	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.4e-10	37.5
WP_000087636.1\|2692223_2693303_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	3.0e-101	52.5
2693439:2693468	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2865695 : 2906393

Salmonella_phage(28.57%)

tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000938186.1\|2865695_2866376_+\|protease	type III secretion system effector protease PipA	Q9MBM0	Phage_Gifsy-2	2.2e-81	71.0
WP_000374046.1\|2866994_2867654_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	2.7e-44	52.4
WP_000904449.1\|2867740_2868070_+	sulfurtransferase TusE	NA	NA	NA	NA
WP_000072884.1\|2868066_2868348_-	acylphosphatase	NA	NA	NA	NA
WP_000548080.1\|2868396_2869176_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_000859416.1\|2869201_2869750_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_000140478.1\|2869964_2871176_+	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_000561983.1\|2871233_2871551_+	heat shock protein HspQ	NA	NA	NA	NA
WP_001676378.1\|2871595_2872009_-	CoA-binding protein	NA	NA	NA	NA
WP_000847719.1\|2872182_2872845_+	DUF2057 family protein	NA	NA	NA	NA
WP_000424187.1\|2872939_2873398_+	methylglyoxal synthase	NA	NA	NA	NA
WP_000420505.1\|2873433_2875488_-	DNA helicase IV	A7KV33	Bacillus_phage	8.5e-20	27.6
WP_001261222.1\|2875611_2876058_+	YccF domain-containing protein	NA	NA	NA	NA
WP_000950876.1\|2876076_2878230_+	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_066038538.1\|2878216_2878822_-	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_000288733.1\|2879038_2879548_+	cell division inhibitor SulA	NA	NA	NA	NA
WP_001674965.1\|2879904_2880957_+	porin OmpA	NA	NA	NA	NA
WP_000877172.1\|2881028_2881481_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_000156448.1\|2881666_2883427_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000227928.1\|2883495_2884014_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_001537784.1\|2884113_2884281_-	ribosome modulation factor	NA	NA	NA	NA
WP_000759136.1\|2884536_2885100_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_000433414.1\|2885096_2886737_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_000333139.1\|2886741_2887995_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_000053044.1\|2888009_2889917_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.4e-53	29.8
WP_001086485.1\|2889929_2892038_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_000224079.1\|2892136_2893246_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_001574119.1\|2893242_2893785_-	cell division protein ZapC	NA	NA	NA	NA
WP_000291723.1\|2893950_2894961_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_000193790.1\|2895168_2897781_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	6.3e-20	22.8
WP_000497441.1\|2898207_2898399_+	DinI-like family protein	S4TNM0	Salmonella_phage	6.2e-26	95.2
WP_001525490.1\|2898669_2899356_+	hypothetical protein	NA	NA	NA	NA
WP_000334547.1\|2899715_2900342_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	1.4e-66	63.2
WP_001674638.1\|2900989_2901958_-	SPI-2 type III secretion system effector SseI	Q9MBL9	Phage_Gifsy-2	3.0e-193	99.4
WP_072100753.1\|2902183_2902432_+\|tail	phage tail protein	A0A1B0VCD0	Salmonella_phage	2.1e-18	66.2
WP_000143167.1\|2902435_2903017_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.7e-95	89.5
WP_000583382.1\|2903016_2904726_-\|tail	tail fiber protein	A0A0U2SAV1	Escherichia_phage	1.5e-91	66.0
WP_000729406.1\|2904722_2905349_-	hypothetical protein	A0A0U2RK03	Escherichia_phage	3.3e-92	71.6
WP_000274547.1\|2905332_2905962_-	hypothetical protein	A0A0U2RJZ0	Escherichia_phage	1.6e-75	65.9
WP_001676370.1\|2905982_2906393_+	enterohemolysin	H6WRX0	Salmonella_phage	5.0e-33	100.0

DBSCAN-SWA_8

2977672 : 2984985

Ralstonia_phage(16.67%)

integrase,protease

attL 2972469:2972483|attR 2983721:2983735

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2972469:2972483	attL	NA	NA	NA	NA
WP_001539594.1\|2977672_2978050_+\|integrase	integrase	A0A077KET4	Ralstonia_phage	1.2e-20	41.0
WP_001117984.1\|2978211_2978409_+	hypothetical protein	NA	NA	NA	NA
WP_000934064.1\|2978621_2980898_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.2e-165	42.3
WP_000520789.1\|2980928_2981249_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	4.5e-13	45.7
WP_000447499.1\|2981572_2981794_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
WP_000125875.1\|2981923_2983870_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.0e-39	43.1
2983721:2983735	attR	NA	NA	NA	NA
WP_001201751.1\|2983866_2984985_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.4e-08	38.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012397

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP012396

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection