CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP015256	Bacillus thuringiensis Bt18247 plasmid p12509, complete sequence	0 crisprs	NA	0	0
NZ_CP015250	Bacillus thuringiensis Bt18247, complete genome	9 crisprs	cas3,csa3,WYL,c2c9_V-U4,RT,DinG,cas14j,cas14k,DEDDh	4	16
NZ_CP015252	Bacillus thuringiensis Bt18247 plasmid p130548 sequence	0 crisprs	NA	0	1
NZ_CP015251	Bacillus thuringiensis Bt18247 plasmid p174778, complete sequence	0 crisprs	NA	0	1
NZ_CP015255	Bacillus thuringiensis Bt18247 plasmid p15092, complete sequence	0 crisprs	NA	0	0
NZ_CP015253	Bacillus thuringiensis Bt18247 plasmid p113275, complete sequence	0 crisprs	RT,csa3	0	2
NZ_CP015254	Bacillus thuringiensis Bt18247 plasmid p81952, complete sequence	0 crisprs	RT,csa3	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015250_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_1

1651700-1651975

Orphan

Consensus_repeat	Method
AGCACCTTGAGGTCCAGTAGCNCC	CRT

5 spacers

The CRISPR arrays of NZ_CP015250_1

>merge|NZ_CP015250|1|1651700-1651975|CRT
AGCACCTTGAGGTCCAGTAGCCCCAGTAGCGCCTGCTGGCCCTTGAGCACCTTGAGGTCCAGTAGCCCCAGTAGCGCCTGCTGGCCCTTGAACGCCTTGAGCACCTTGAGCACCAGTAGCGCCTGCTGGCCCTTGAATACCTTGAGCACCTTGAGGTCCAGTAGCCCCTTGAGCACCTGCTGGTCCCTGAGCACCTTGAGGTCCTTGAGCCCCAGTAGCGCCTTGAGCACCAGCCGGACCTTGAGGTCCAGTAGCGCCTTGAGGTCCAGTAGCACC

>NZ_CP015250|1|1|1651700-1651975|CRT
AGCACCTTGAGGTCCAGTAGCCCC	AGTAGCGCCTGCTGGCCCTTG
AGCACCTTGAGGTCCAGTAGCCCC	AGTAGCGCCTGCTGGCCCTTGAACGCCTTG
AGCACCTTGAGCACCAGTAGCGCC	TGCTGGCCCTTGAATACCTTG
AGCACCTTGAGGTCCAGTAGCCCC	TTGAGCACCTGCTGGTCCCTG
AGCACCTTGAGGTCCTTGAGCCCC	AGTAGCGCCTTGAGCACCAGCCGGACCTTGAGGTCCAGT
AGCGCCTTGAGGTCCAGTAGCACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_069355305.1\|1643201_1644410_+\|NO-inducible-flavohemoprotein	unknown	unknown	gnl\|CDD\|237337
NZ_CP015250.1\|WP_000067551.1\|1663117_1663609_+\|DUF3907-family-protein	unknown	unknown	gnl\|CDD\|379028
NZ_CP015250.1\|WP_053564895.1\|1662705_1663095_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_001094860.1\|1655186_1655381_-\|DUF3924-domain-containing-protein	unknown	unknown	gnl\|CDD\|289807
NZ_CP015250.1\|WP_053564902.1\|1645646_1646447_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP015250.1\|WP_000600585.1\|1644442_1644955_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_CP015250.1\|WP_069355309.1\|1659148_1659937_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_069355306.1\|1648506_1650549_+\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_CP015250.1\|WP_053564903.1\|1642523_1643042_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_064531931.1\|1641311_1642409_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100081
NZ_CP015250.1\|WP_000806236.1\|1655502_1656033_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271192
NZ_CP015250.1\|WP_000380276.1\|1646564_1647563_-\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NZ_CP015250.1\|WP_064531936.1\|1650628_1651057_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_053564898.1\|1654126_1654972_+\|DUF72-domain-containing-protein	unknown	unknown	gnl\|CDD\|224714
NZ_CP015250.1\|WP_000010853.1\|1659941_1662521_-\|bifunctional-lysylphosphatidylglycerol-flippase/synthetase-MprF	unknown	unknown	gnl\|CDD\|225451
NZ_CP015250.1\|WP_000110707.1\|1658264_1658972_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP015250.1\|WP_069355308.1\|1656140_1657955_-\|HAMP-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|274368
NZ_CP015250.1\|WP_000883009.1\|1645125_1645353_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_053564899.1\|1652721_1653987_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|236901
NZ_CP015250.1\|WP_000231445.1\|1647574_1648195_-\|DUF47-domain-containing-protein	unknown	unknown	gnl\|CDD\|224310

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_069355305.1\|1643201_1644410_+\|NO-inducible-flavohemoprotein	gnl\|CDD\|237337	PRK13289, PRK13289, NO-inducible flavohemoprotein.	0
NZ_CP015250.1\|WP_000067551.1\|1663117_1663609_+\|DUF3907-family-protein	gnl\|CDD\|379028	pfam13047, DUF3907, Protein of unknown function (DUF3907). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 160 amino acids in length. There is a conserved AYTG sequence motif.	3.16407e-78
NZ_CP015250.1\|WP_001094860.1\|1655186_1655381_-\|DUF3924-domain-containing-protein	gnl\|CDD\|289807	pfam13062, DUF3924, Protein of unknown function (DUF3924). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length.	4.03713e-27
NZ_CP015250.1\|WP_053564902.1\|1645646_1646447_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.95752e-36
NZ_CP015250.1\|WP_000600585.1\|1644442_1644955_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	4.52796e-23
NZ_CP015250.1\|WP_000010853.1\|1659941_1662521_-\|bifunctional-lysylphosphatidylglycerol-flippase/synthetase-MprF	gnl\|CDD\|225451	COG2898, COG2898, Uncharacterized conserved protein [Function unknown].	6.25958e-139
NZ_CP015250.1\|WP_069355306.1\|1648506_1650549_+\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP015250.1\|WP_064531931.1\|1641311_1642409_+\|site-2-protease-family-protein	gnl\|CDD\|100081	cd06160, S2P-M50_like_2, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with additional putative N- and C-terminal transmembrane spanning regions, relative to the core protein, and no PDZ domains.	2.72262e-41
NZ_CP015250.1\|WP_000806236.1\|1655502_1656033_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.9028e-41
NZ_CP015250.1\|WP_053564898.1\|1654126_1654972_+\|DUF72-domain-containing-protein	gnl\|CDD\|224714	COG1801, COG1801, Uncharacterized conserved protein [Function unknown].	1.70089e-73
NZ_CP015250.1\|WP_000110707.1\|1658264_1658972_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	1.77954e-168
NZ_CP015250.1\|WP_069355308.1\|1656140_1657955_-\|HAMP-domain-containing-sensor-histidine-kinase	gnl\|CDD\|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.23154e-61
NZ_CP015250.1\|WP_000231445.1\|1647574_1648195_-\|DUF47-domain-containing-protein	gnl\|CDD\|224310	COG1392, COG1392, Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism].	7.0682e-51
NZ_CP015250.1\|WP_053564899.1\|1652721_1653987_-\|PAS-domain-containing-protein	gnl\|CDD\|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.11436e-64
NZ_CP015250.1\|WP_000380276.1\|1646564_1647563_-\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	2.92405e-106

>NZ_CP015250.1|WP_064531936.1|1650628_1651057_-|hypothetical-protein
MRVMSLIRIWIALMVCIILCVGFFLTLKYSTISKAERKTVPYKLLYTKQNDIPYSNSTNNEKKVIKGMLITKASNYETLLHIAETIKDQYTNKGIDEITLSIHNENNGSYEEELPYEPISKGTIIVTYDSQSFGSTNITLNE
>NZ_CP015250.1|WP_069355306.1|1648506_1650549_+|PBP1A-family-penicillin-binding-protein
MKLKNTHFKKMLEWFNKRKKLRNSLIVLGSVLVTIFIAVNIIISTQDISELKQAVPQPTLIYDANNEVATKLASSKTEGVKRKDIPDIMVQAIVAVEDKEFFNHHGIYYSGIISAVFKNITAGEVVAGGSTITQQLAKNVFLTQDRTFSRKIKEYFLTKKIERTYTKDEIIEMYMNQIYFGEGAWGIKRAAKSYFDKEVKDLSISEAATIAGLIKAPSAYSPYKNFNKSIERRNVVLSLMKEQGYISEEQYNKEKESGLVLKRGVDDKYKGKYSQYVDYIVREAMDKYELTQNEILAGGYRIYTELDPKKQQAVEDVVNNDSYFKDSGSDQLMQTGVVLINPKTGGVPALVGGRGPYQFLQFNHATQLKRQPGSTLKPLAVYVPALEQGYEVYDILKDEPFHIKEYEPKNSDQAFHGNVTMYEAVAKSYNVSAVWLLEQIGLDKGLKSLERFGIPLVPEDRTYPIALGGMHVGTSPFVMAQAYSTFANDGVQVEAHAIREVQNAEGEIIGKWYKKETRVTSEKIAQKMTYLLKGVVEKGTGGKAKVNNVDTAGKTGTTQLVNGPSVGAKDSWFVGYTPDLVGAIWVGYDKTDSEHYVPGGSQITTTMFRDIMKKANANPAQKAFQLSLISEADYKKQLQTIEEEKRRKEEEKKRQEEEQQRKKEQQEWFDKVKEWIPSLW
>NZ_CP015250.1|WP_000231445.1|1647574_1648195_-|DUF47-domain-containing-protein
MVFKSKKDKFSEMLMNVSENLKEGAQFFVEYKIKNASDLKEFSMRMKEYESKGDSFIHEIIMELNKAFITPIEREDILQLAMSMDDVLDGLDHSAGLFEMYSITEADEYMIKFVEAINQCAIEIANSVELLSKKKLVDIRTNAIKIKDYESQCDDIRRHAIKHLFSREKDPIKIIQFKEIYEELEEVADSCQSVANVLETIIMKNA
>NZ_CP015250.1|WP_000380276.1|1646564_1647563_-|inorganic-phosphate-transporter
MDTLLILTVLVVICALAFDFINGFHDTANAIATAVSTKALKPRHAIIMAAIMNFLGAMTFTGVAKTITKDIVDPFALQNGSLVILAALLAAIAWNLITWYYGIPSSSSHAIIGSIAGAAIAAAGISSLNLKGFIKILEALIISPIIAFVIGYIVYSIFKVVFKNFNLTKTNKNFRIFQIFTAALQAYTHGTNDAQKAMGIITMALMANNYHTSSDIPFWVQLSCAIAMGLGTSVGGWKIIKTVGGQIMKIRPVNGVAADLSSSLVIFGATFIHLPVSTTHVISSSILGVGASHRVKGVKWGTAKRMLITWVITLPISASLAALFYYLLHFVF
>NZ_CP015250.1|WP_053564902.1|1645646_1646447_-|sulfite-exporter-TauE/SafE-family-protein
MEYIMLLFIGLIAGTVGSLVGLGGGIIIVPLLIGLHSLSPQLAVGTSMVTVVFTGLSSTLTYMKHKRVDYKSGLILFIGSGPGGIIGSWANKFLNQDTFSLYFGVFLIFVSILLMLRDKLKPLSLSNTSVIKRSFTDNDGNTVHYQFPPFLAIFIAFIVGFISGLFGIGGGALLVPAMMLLFAFPAHIAVATSMFIVFLSAIVSSATHISLGNVSWIYALILIPGAWIGGKIGAYINTKLSGNAVINLLRITLIILGTRLIIISLL
>NZ_CP015250.1|WP_000883009.1|1645125_1645353_+|hypothetical-protein
MLDAMRMTDMRIPANAIIHVEEMKGGVVLSVEVDGQIIYTMAYDEETDSYAELYDRNDKRACQVHEDFMGWSLLH
>NZ_CP015250.1|WP_000600585.1|1644442_1644955_-|Crp/Fnr-family-transcriptional-regulator
MILHKGDVLFRQGEDGPLYFIKTGLLKVVRLEEDGTPFLFNIIVPGETIPHHSLISPKEYHGTAIALIKTEVEPITSSEWYERLQANPESYANIAMQLQSKLRMMQQRIDQLTTVSPKERLHRLQEWFTLYLGDIPIYEILTQTEIGQLIGIRRETVNRLLREQIKNEVK
>NZ_CP015250.1|WP_069355305.1|1643201_1644410_+|NO-inducible-flavohemoprotein
MLSAKTIEIVKSTVPLLQEKGVEITTRFYQILFSEHPELLNIFNHTNQKKGRQQQALANAVYAAATYIDNLEAIIPVVKQIGHKHRSLGIKAEHYPIVGTCLLRAIKEVAGAPDEVLNAWGEAYGVIADAFISIEAEMYEEAAHKEGGWKDFRNFVIVKKVKESDVITSFYLKPEDGGKVSSFIPGQYVTVQINIEGETYTHNRQYSLSDAPGKEYYRISVKKEKGVDTPDGKVSNYLHEHVKEGDVLPVSAPAGDFVLNMDSTLPVVLISGGVGITPMMSMLNTLIEQDSKRNVYFVHAAINSNTHAMKEHVKAVENEYEQVKAYTCYSAPTEKDIEMKNFDKEGFVESEWLKTIIPTTEAEFYFCGPVAFMKHINAALTDLGVKQEHIHYEFFGPATSLQ
>NZ_CP015250.1|WP_053564903.1|1642523_1643042_+|hypothetical-protein
MKKLLSVFGIIIVMIIASYSLMKVLLHYANKPAEVNTIAQVEDVQEETKVLDFIRMTHESYNNFLNYGKAENYTDGDWKQFKQWFQQQEPSLKNIHTEIKNEKIKRDVNRSYEIVKKGVELQNIEYVVYAHRVYHDLDIIVNKYRGETNIWGYTEFGDGKDRKVIEQAIQTK
>NZ_CP015250.1|WP_064531931.1|1641311_1642409_+|site-2-protease-family-protein
MKNNKKGLWGIIVAIGLFLLSKLKWVFAIFKLAKFSTVFSMFLSLGAYAVLYGWKFGVALIYLLFVHEMGHLWAAKRKGIPTSPAIFIPFMGALIGMKEMPKNAKDEAYIAYMGPLFGLLSFLPAIPLYIMTQEPFWALVILLGSMINFFNLIPVSPLDGGRIISVVSTKIWGAGLILLLGYSIYFKSILGGFIVIIGCMELYRVIKRDEPIKELGHKIDGMKEYVARLEEELKETGAVHRTIYMMHHEMNALRQSEREKELQIGELQKMEVLEYLLPKFEPLDYVPYEDEIDEYTIHIREAFEASERKLNEWKTEKEQQENYYKVDTKTKWTVFACYIGLIAILGYTAYEGYIVLQEHLPRRNV
>NZ_CP015250.1|WP_053564899.1|1652721_1653987_-|PAS-domain-containing-protein
MLPNDATVSHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLRIKKTRTTHSIQEIPKENKEANFQLTCDSLFLFEQLEKHFVHIFDAFSHHVTFVDSKGNITLCNQVAADDFGVIRNDIIGKPIQQLLNLPEEKIKAIETLRTGTEIYNEEVLDKNYGIINNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQESVSTSNQELFKNLLIPELDRANNIITKFLAVSKTREFTREPFPINTFLRDYIQQLLASEVSLHNISIDYNFSNELDDILVNIDRHELVQVFLNLFQNAVDAQGDKPLSIQITSYRLDNFVRITFTDNGIGIPPAIQEYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSAPDGTTFTISIPILPKVNREAINL
>NZ_CP015250.1|WP_053564898.1|1654126_1654972_+|DUF72-domain-containing-protein
MLFIGVTGWGDHNSLYIDSYENRNKLRTYSEYFPIVEVDSSFYAMQPARNYIKWAMETPKDFSFVVKAYQGMTGHMKGEIPFSTFDEMFDVYKQSILPLLEADKLKTILFQYPPWFDCKKKNVDFLRYTKEKMEGLPCAIEFRNQTWFYPEMIDKTLQFLEQEKWVHTICDEPQAGIGSVPLVLEVTNSDMALIRFHGRNVHGWLDKGENWRAVRCLYRYNNKELEEWVERLEQLKKKTKDIYVLFNNNSGGDAADNAKQLMKMMNITYGEPKPEQLNFFE
>NZ_CP015250.1|WP_001094860.1|1655186_1655381_-|DUF3924-domain-containing-protein
MNTLTIELPKETAEKLDLLKQAYEKKTGASISESTLVQTLISKEFIQAITPFDLQQFVNGKEQH
>NZ_CP015250.1|WP_000806236.1|1655502_1656033_-|tyrosine-type-recombinase/integrase
MKQAGQPIQNEKQLETIKNILLQSSKRDGLLFVLAVNSGLKVSEILQLKVSDVIDENENVRHSILFYNEKVKKHKWFAVNEDLQHAIEDYMKERKTWKRNEPLLKSQKGTKSITRQHAWYILNKAAKEVGLEGISSHTLRKTWGYCAYKSGVDIAFLQHFFDHSTPSKTLKYIGIA
>NZ_CP015250.1|WP_069355308.1|1656140_1657955_-|HAMP-domain-containing-sensor-histidine-kinase
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVDNYDKSDKSYEKVRKLKQEFHDKTNADMQFLDSNGIIKSDNNYYIDVFNPNNNKQYSIPLNNLLTPEEYNKFENLGLKKDVIINVDGVVQENNIITPQKLGTNYNQWQNEHFYSDFQSINGNPSKNRLTSRYKSTTRIVFTGVITKLQLPSKAEVRLANDIETLQAVQYFADIIRDGTSNSNQLNTFILDGGENIKNSIFVKPIIENGKITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTSYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELTQQVYTKLLFSMEEKHLQVNVDADPSILVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSIIEAEDTVKVEIENTGNPIPEESLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK
>NZ_CP015250.1|WP_000110707.1|1658264_1658972_-|purine-nucleoside-phosphorylase
MSVHIEAKQGEIAESILLPGDPLRAKYIAETFLEDVTCYNNVRGMLGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSYGVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFPGFDFAPAANFDLLKKAYDAGTEKGLHVRVGNVLTADVFYRESMDMVKKLGDYGVLAVEMETTALYTLAAKYGVNALSVLTVSDHIFTGEETTSEERQTTFNEMIEIALDAAIQQ
>NZ_CP015250.1|WP_069355309.1|1659148_1659937_+|hypothetical-protein
MVGDVLKNLVIGLIALVLIVAGGFYIKKYQENEETVGDVQEVKWDVSNGKENEKVDIVFQLLNKKNNEIRGVNDQIRAVIVDGQLKHIQQIKPTFAGNGSYKLSSKIAKDEEYTIFLYEDKNKSVESFARKDFGRTKEENNKKKVKFPIDSVLTKKIGEYEVSLLFGALHPNEPVTLTFQFQAKKGEKLKLHSERGEVESLYIVDETKENFLYAMPVDTDEQLQYRITFPAEGTYKMWGNFYINGKKYEKEFIVQVQKRKNS
>NZ_CP015250.1|WP_000010853.1|1659941_1662521_-|bifunctional-lysylphosphatidylglycerol-flippase/synthetase-MprF
MSFSWKRFLQIGKIIFPFVVLTIVFFQAKKELAGISFLEAIDTIKNIPTGGVFLAITLGAFAVSTMFFYDYVMLRYLKADIPVQKIFRISWIANTLNGFIGFGGLVGAGVRTMLYRPYIKENGKLIKSIAWMTTAFINGLAILSFLGLIGILDTRFILHEKPWLWPVLIFFALFVPIYIGFSKLKNRKATQTEGQEEEEKNPTVLYSLVSLVEWVSAGIVMYVILLLFGIEIEFQKFLGVYVIAALAGVVSLVPGGLGSFDLVFLTGLGQYGIDTGVLLPAMLLYRLVYYILPFCLGLIFAAFEMTGVAIKKFEDKPFIAPALETTGVIWTLQRDFLGKLGSWASAALTVFAGLMVILSTILPTSINRAHALHILAPKHLIQFSFSLSLTFGILLLILSRGIYYGTKRSYYMTIVSLIGAAIFNTLKGIDVEETFILLIVLAVLYMLRKRFVREKMEVSLSDIVKVFIFLLVTLYLYKNLGILFAGAKEAFKPDFVVRNITQVKRSALAAAFFVPTFLLIGSLIANRYRNEFPGQPANDKRLQNFLDEHGGNVLSHLGFLGDKQFFFSSDGKALILFSITGKRLIVLGDPIGDPSSYRTVLQEFLAEADRFGYICVFYQIESKWMSLYHDFGYNFFKLGEEAVVDLNTFTITGKKRAGMRATFNRFEREGYTFSIHEPPFSDELYEELRKVSDAWLGGKKEKGFSLGYFDREYISRAPIATLSDADGKIIAFTTFMPVYQNGSLSVDLMRYYPDAPSGIMDAIFIHLFQWAKENEYHSFNIGMAPLSNVGLSTQSFWSERVAAAIFNNVRYTYSFSGLRHFKEKYKPAWSGKYLAFRKNHSLPITMLSVTKLIGKRKNS
>NZ_CP015250.1|WP_053564895.1|1662705_1663095_+|hypothetical-protein
MIIKGYVGYELEKAKPNTSEDFFNRSEVTYILNDKEKTFSVLYVRYFEEVLQEITPFEGNPVYKVEEQNIYLRDIVAICCLVKDRELRAQKRLYLNNMEEFQQYFDEGTVLKVQEILAELHKNKRVEIA
>NZ_CP015250.1|WP_000067551.1|1663117_1663609_+|DUF3907-family-protein
MSNLMVENQTEQVSIFLEDAIHLITNYVNYHTLPSLLEETPAGNEQYYKGLLASMRRLLVFCEEGHDACFVLLNSQPFRKTAAEKILYKIYHQVIAEFFSPKSDYWYENSRSAYTGKNSIVFQQTPPASLGQVMKSLEGKFQLMREELEYYETDYQTKMLHKY

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Crispr_ID: NZ_CP015250_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_2

1741372-1741533

Orphan

Consensus_repeat	Method
TCAACAACAGCAGCAACCTTATGTGAATCAAGCTCAACAATCACAAGCTCAGCAACC	PILER-CR

2 spacers

DinG

The CRISPR arrays of NZ_CP015250_2

>merge|NZ_CP015250|2|1741372-1741533|PILER-CR
TCAACAACAGCAGCAACCTTATGTAAATCAGGCCCAACAACCACAACAGCAGCAACCTTATGTGAATCAAGCTCAACAATCACAAGCTCAGCAACCATACATGAATCAACAACAGCAGCAACCTTATGTGAATCAAGCTCAACAATCACAAGCTCAGCAACC

>NZ_CP015250|2|1|1741372-1741533|PILER-CR
TCAACAACAGCAGCAACCTTATGTAAATCAGGCCCAACAACCACAACAGCAGCAACCTTATG	TGAATCAAGCTCAACAAT
CACAAGCTCAGCAACCATACATGAATCAACAACAGCAGCAACCTTATGTGAATCAAGCTCAA	CAAT
CACAAGCTCAGCAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_000728542.1\|1733377_1734085_+\|DNA-replication-protein-DnaD	unknown	unknown	gnl\|CDD\|226445
NZ_CP015250.1\|WP_000546292.1\|1741983_1742406_+\|spore-coat-protein	unknown	unknown	gnl\|CDD\|371387
NZ_CP015250.1\|WP_000521224.1\|1744107_1745247_+\|class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223194
NZ_CP015250.1\|WP_069355319.1\|1747669_1749187_+\|carboxypeptidase	unknown	unknown	gnl\|CDD\|341054
NZ_CP015250.1\|WP_000242652.1\|1740835_1741027_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|290882
NZ_CP015250.1\|WP_001252036.1\|1740206_1740449_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_000866496.1\|1750940_1751534_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP015250.1\|WP_000786937.1\|1740464_1740809_+\|YppE-family-protein	unknown	unknown	gnl\|CDD\|378052
NZ_CP015250.1\|WP_000622431.1\|1743114_1743450_+\|cell-division-regulator-GpsB	unknown	unknown	gnl\|CDD\|237616
NZ_CP015250.1\|WP_000493700.1\|1745630_1747568_+\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP015250.1\|WP_142245165.1\|1738785_1739790_+\|DUF2515-domain-containing-protein	unknown	unknown	gnl\|CDD\|371209
NZ_CP015250.1\|WP_000809230.1\|1751537_1752860_+\|xanthine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP015250.1\|WP_044307511.1\|1749868_1750615_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|171806
NZ_CP015250.1\|WP_069355320.1\|1749235_1749709_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP015250.1\|WP_000368570.1\|1745308_1745491_+\|DUF3921-domain-containing-protein	unknown	unknown	gnl\|CDD\|289805
NZ_CP015250.1\|WP_000155599.1\|1738058_1738661_-\|Holliday-junction-resolvase-RecU	unknown	unknown	gnl\|CDD\|235015
NZ_CP015250.1\|WP_000933035.1\|1734100_1734748_+\|endonuclease-III	unknown	unknown	gnl\|CDD\|223255
NZ_CP015250.1\|WP_069355316.1\|1735295_1737992_-\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_CP015250.1\|WP_000761571.1\|1732069_1733257_+\|aspartate-transaminase-AspB	unknown	unknown	gnl\|CDD\|235596
NZ_CP015250.1\|WP_029441862.1\|1734751_1735270_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_000728542.1\|1733377_1734085_+\|DNA-replication-protein-DnaD	gnl\|CDD\|226445	COG3935, DnaD, Putative primosome component and related proteins [DNA replication, recombination, and repair].	1.97344e-62
NZ_CP015250.1\|WP_000622431.1\|1743114_1743450_+\|cell-division-regulator-GpsB	gnl\|CDD\|237616	PRK14127, PRK14127, cell division regulator GpsB.	1.92897e-44
NZ_CP015250.1\|WP_000521224.1\|1744107_1745247_+\|class-I-SAM-dependent-RNA-methyltransferase	gnl\|CDD\|223194	COG0116, COG0116, Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair].	0
NZ_CP015250.1\|WP_069355319.1\|1747669_1749187_+\|carboxypeptidase	gnl\|CDD\|341054	cd06460, M32_Taq, Peptidase family M32, which includes thermostable carboxypeptidases TaqCP, PfuCP and FisCP. Peptidase family M32 is a subclass of metallocarboxypeptidases, distributed mainly in bacteria and archaea, whose members contain a HEXXH motif that participates in coordinating a divalent cation such as Zn2+ or Co2+. It includes the thermostable carboxypeptidases (E.C. 3.4.17.19) from Thermus aquaticus (TaqCP) and Pyrococcus furiosus (PfuCP), which have broad specificities toward a wide range of C-terminal substrates that include basic, aromatic, neutral and polar amino acids. These enzymes have a similar fold to the M3 peptidases such as neurolysin and the M2 angiotensin converting enzyme (ACE). The keratin-degrading extremophilic eubacterium Fervidobacterium islandicum M32 carboxypeptidase (FisCP) plays an important role in cellular metabolism, and significantly enhances the degradation of native chicken feathers. It has been shown to mainly cleave the C-termini of peptides with a basic amino acid sequence. Novel M32 peptidases from some eukaryotes: protozoa Trypanosoma cruzi, a causative agent of Chagas' disease, and Leishmania major, a parasite that causes leishmaniasis, have been identified, thus making these enzymes an attractive potential target for drug development against these organisms.	0
NZ_CP015250.1\|WP_000242652.1\|1740835_1741027_-\|hypothetical-protein	gnl\|CDD\|290882	pfam14178, YppF, YppF-like protein. The YppF-like protein family includes the B. subtilis YppF protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There is a conserved LLDF sequence motif.	2.84918e-29
NZ_CP015250.1\|WP_000866496.1\|1750940_1751534_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	1.08441e-122
NZ_CP015250.1\|WP_000786937.1\|1740464_1740809_+\|YppE-family-protein	gnl\|CDD\|378052	pfam08807, DUF1798, Bacterial domain of unknown function (DUF1798). This domain is found in many hypothetical proteins. The structure of one of the proteins in this family has been solved and it adopts an all alpha helical fold.	6.66665e-36
NZ_CP015250.1\|WP_000546292.1\|1741983_1742406_+\|spore-coat-protein	gnl\|CDD\|371387	pfam11122, Spore-coat_CotD, Inner spore coat protein D. This family is conserved in the Enterobacteriaceae family. CotD is an inner spore coat protein that is expressed in the middle phase of mother cell gene expression. Along with CotD, CotH, CotS and CotT it is assumed to assemble into the loose skeleton of the matrix, between the shells of SpoIVA and CotE. Coat proteins do not share much sequence similarity between species, but this does not imply they do not share secondary, tertiary, or quaternary features.	1.80691e-13
NZ_CP015250.1\|WP_000493700.1\|1745630_1747568_+\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	9.15673e-110
NZ_CP015250.1\|WP_142245165.1\|1738785_1739790_+\|DUF2515-domain-containing-protein	gnl\|CDD\|371209	pfam10720, DUF2515, Protein of unknown function (DUF2515). This family is conserved in Firmicutes. Several members are annotated as YppC. The function is not known.	4.51871e-174
NZ_CP015250.1\|WP_044307511.1\|1749868_1750615_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|171806	PRK12897, PRK12897, type I methionyl aminopeptidase.	0
NZ_CP015250.1\|WP_069355320.1\|1749235_1749709_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.58234e-12
NZ_CP015250.1\|WP_000368570.1\|1745308_1745491_+\|DUF3921-domain-containing-protein	gnl\|CDD\|289805	pfam13060, DUF3921, Protein of unknown function (DUF3921). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length.	1.04951e-26
NZ_CP015250.1\|WP_000155599.1\|1738058_1738661_-\|Holliday-junction-resolvase-RecU	gnl\|CDD\|235015	PRK02234, recU, Holliday junction-specific endonuclease; Reviewed.	1.10731e-116
NZ_CP015250.1\|WP_000933035.1\|1734100_1734748_+\|endonuclease-III	gnl\|CDD\|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	3.94636e-113
NZ_CP015250.1\|WP_069355316.1\|1735295_1737992_-\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	0
NZ_CP015250.1\|WP_000761571.1\|1732069_1733257_+\|aspartate-transaminase-AspB	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NZ_CP015250.1\|WP_000809230.1\|1751537_1752860_+\|xanthine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	0

>NZ_CP015250.1|WP_000242652.1|1740835_1741027_-|hypothetical-protein
MVLGDLKQAFSQKKGYCTENANELLDFARHWYLEGKICISDYRTLIKELEINGATKPTTMTEA
>NZ_CP015250.1|WP_000786937.1|1740464_1740809_+|YppE-family-protein
MKNEALIQSSEKLMQYNNEANVKKRELIEYDFYKDMKPFVDMVDEELEKWKELAYTWIKEEKPKYIHVQQIDQVYDNLQTNVLQCFVNKGKGKRFFETHQAVSYTLQNIVEQCK
>NZ_CP015250.1|WP_001252036.1|1740206_1740449_+|hypothetical-protein
MAMVQKEDVMKKMDQMLSSLDLLEMNIGIRMNHALKDASEKICNKIEITEMHIEHMENKLVHHEEKGNWVKTFQNVVVSA
>NZ_CP015250.1|WP_142245165.1|1738785_1739790_+|DUF2515-domain-containing-protein
MKMKQNREKNFCTEKEKAIIRNIKKKTEIANVDNISRTQSYQEYYLRNSEIRWAFLASMVSRNAGWNMTDLEGRYYATVLPETVKKHLFLLYEQANWIIFLDAFPQLLLYEESKKRRAPLFHLLQYFSVSIFMEKEWLLFWERRDMNRLMTALIINEQNKIQKPVIENTYFKKHVFHTALFKVQERFHISAVIFPTIEGRMYGFSVYQFETLKQRIELGKKLAWLLFHPIYNGSFYKFALQTTHTGSREDYEVYAQETRKSYTPTLRDIYPVILHEEIKMRDWFCTNMKMNVLFVLEEPKEEVNITEWYRRKREQIYRLSIVNRFAKRMDEFMI
>NZ_CP015250.1|WP_000155599.1|1738058_1738661_-|Holliday-junction-resolvase-RecU
MTIRYPNGKRYNQASQPQKTPIKTHTYSNRGMSLEEELNETNQYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVVAHNGIAFVIIKFTLFDEFYLLDAKHIIAFWNRQNTGGRKSITKEEIEEHGSLLSCGYHPRIDYIRVLDTVYFS
>NZ_CP015250.1|WP_069355316.1|1735295_1737992_-|PBP1A-family-penicillin-binding-protein
MSDNYRSRTERNHVKNQEKKTNKEEKPKKKGSFFKKFLIGCLLLGIVGLVAGVSAFFVMVKDAPKLDKSKLVNPLSTKFLDKNGNFFYEYGAEKRTHVTYDQIPKVVENAFLATEDSRFYDHNGIDFKRTTKAVMENVTGGFGSQGGSTITQQVVKNYFLTMDKTAKRKVQEWYLSYKLEQQYSKHEILEMYLNKINLGNRSYGIATAAQKYYGKDLKDLQLHEAAMLAGLPQGPNIYDPTKKENVERATNRRNVVLSLMNRHGYITKEEMNNAVKIPVTEGLQPSSEVTEMKYQAFLDAVVKEVEKEYPDVNIGSDGLTIHTTLDQDAQDYADKIMDGNLIKYPDDQFQGSFVFMDTQSGEVRAIGAGRKESKSTFKGHNMATDLKRQVGSTMKPIFDYGPAIENLQWSTYHQLNDSEYTYSNGKKIQNATKSYKGDVSLREALKKSLNIPALKTAQTVGLNKSKEFAEGLGMTFKEGKVYESTAIGSNDSSPLEVAGAYATFGNSGNYNKPHFVKEVTFPDGKKKSFKPKEHRAMQDYTAYMVTDVLRDVVKPGSGGTGPTAYVSGVDVAGKTGTQNFDESVLQKYDIPADANRDSWFAGYTPQYTMAVWTGYEKDGPKNYVSDRSTRIAQQMFQVMMSKFATDKSRFERPSSVQEINGELYVKGAKKDAIKEIKVDAPSGLNVTFDGASTVTLNWSGPAEVDAYAASYKATDGSSGSLSISGTTATLGGIKPGVTYSFSVVAKKGTGTSPAVGASFTAPGGTPDAKKAEEDAKKKADEEAKKKADEEAQKKANEDKVKQDEAKKKADEEAKKQQEQQQEQQRKQQEEAQKKADEEARRKTEEEAKKKAEEEAKKKAEEEAKKKAEEEAKKQQEQQHQNTGGDTPHADGTVITTES
>NZ_CP015250.1|WP_029441862.1|1734751_1735270_+|hypothetical-protein
MERVIEIPKEFHCLPFFKESVNSIEYHTDESFEEIIQNTYFIFDIERQYEPWKEIENSIPAMLNVWKNKHEDIAILFRNRNKQEAEGPMILFAAHLLSVVYWLNEQPVHSLNEMQINTNKLKVQPVNFMERYSFIIKKPSNYHSYIQLAQLYIEIEKLYVKKMITKKKSASR
>NZ_CP015250.1|WP_000933035.1|1734100_1734748_+|endonuclease-III
MLNKTQIRYCLDTMADMYPEAHCELVHDNPFELVIAVALSAQCTDVLVNKVTRNLFQKYKTPEDYLSVSLEELQQDIRSIGLYRNKAKNIQKLCRMLLDDYNGEVPSDRDELTKLPGVGRKTANVVVSVAFGIPAIAVDTHVERVSKRLAICRWKDSVLEVEKTLMKKVPMDEWGVTHHRMIFFGRYHCKAQRPQCEECRLLEVCREGKKRMKVK
>NZ_CP015250.1|WP_000728542.1|1733377_1734085_+|DNA-replication-protein-DnaD
MKKKMMLQWFEQGSIAIPKLLMMHYKKLGLNETEFMVVLHVHTFLESGNSFPTPSEISERMTITEMKCMEVIQALIQKGFLSLEGGQRSEAMMCESYSLQPLWEKILHFLMDESIEEEQKEKKQLQVNLYTVFEKEFGRPLSPFECETLGMWEDQDQHHPNLIQAALREAVMSGKLNFRYIDRILFEWKKNGIKTVDQAQNQGQKFRANQQRAQQMTKQETKFTGKVPFYNWLEQ
>NZ_CP015250.1|WP_000761571.1|1732069_1733257_+|aspartate-transaminase-AspB
MKLAKRVAALTPSSTLEITAKAQALKAEGHDVIGLGAGEPDFNTPEHIMDAAHKAMLEGHTKYTPTGGLQSLKQEIVKKFTRDQGIAYDPSEIIVCNGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEDNEYKITAKQLREAITEKTKAVIINSPSNPTGMIYSKEELQQLGEVCLEHDILIVSDEIYEKLIYGGVEYTSIAQLSNALKEQTLIINGVSKSHSMTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGSQEPVETMRQAFEERLNIIYDKLIQIPGFTCIKPQGAFYLFPNVKEAVALSGYATVDDWAKALLEEEKVALVPGTGFGAPNNVRLSYATSLEQVEKALERIHTFMKSKVQA
>NZ_CP015250.1|WP_000546292.1|1741983_1742406_+|spore-coat-protein
MHHCHPCFGGHKPVGPICTTAPVVHPTKQCVTHSFSTTVVPHIFPTHTTHVHHQQIKNQNFFPQTNSNVNVVDPIDPGFGGGCGPCGHGHHHHGHQISPFGPGPNVSPFGPGPNVSPFLPNNVSPVGPNIGPNVGGIFKK
>NZ_CP015250.1|WP_000622431.1|1743114_1743450_+|cell-division-regulator-GpsB
MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAVTQVPQQPVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
>NZ_CP015250.1|WP_000521224.1|1744107_1745247_+|class-I-SAM-dependent-RNA-methyltransferase
MGKVTLIATAAMGIEALVAREVRDLGYECQVENSKVTFEADEKAICRTNLWLRTADRVKIKVGEFKATTFDELFEKTKALNWGDYIPENGEFPVIGKSLKSELFSVSDCQRIVKKAVVEKLKTTYKRTTWFEEDGPLFRIEIAMLKDIATLTIDASGVGLHKRGYRMDQGEAPLKETLAASLIKLTNWKPDRPFVDPFCGSGTIPIEAALIGQNIAPGFNRGFASDEWGWVGKQNWREARQEAEDLANYDQRLQIIGSDIDHRMIRVAQDNAEEVGLGDLITFKQMQVKDFTTKEDYGYVVTNPPYGERLSEKALVEQLYKEMGQVFRPLDTWSAYVLTSYEAFEKCYGKDASKKRKLFNGFIRTDYYQYFGKRPPRNS
>NZ_CP015250.1|WP_000368570.1|1745308_1745491_+|DUF3921-domain-containing-protein
MDNFQLSMIQKAIHRTYDELGKEVDSQGAIVDEIQKAQEEYLSALSHETAIDKRYLKSLI
>NZ_CP015250.1|WP_000493700.1|1745630_1747568_+|ATP-dependent-DNA-helicase
MFTEKRLPFEVGKQDNFYDKLNEWIGDVFYDILPEKGFEERDEQIFMAFQLERAFQEKKVMFAEAGVGTGKTIVYLLYAICYARYTGKPAIIACADETLIEQLVKEEGDIAKLSEALGLSVDVRLAKSMDNYLCLRKLEDVMSGRAPEVIEDVYYELPQFVFDHGTMQNFTHYGDRKEFPLLNDEEWSKVNWDYFQDCFTCDSRHRCGQTLSREHYRKAADLIICSQDFYMDHIWTYDARKREGQIPLLPESSCVVFDEGHLVEYAAQKALTYRLKQTMMEQLLTRLLQNDIREEFAHLVEETIWQTERFFDVLQENKKEIAGSDRLEITVTEKVTAEAKRLYAKIGEVGDALVFESEMHTVNTYDLNIVDEHLDVLEHSLRLFMHEKNVITWGEEGDGAFTLVIMPRAVEEVLQEKVFSKKIPYIFSSATLSNNDSFAFTANSLGVKDYLSFSVASPFDYEEQMAVNLLSHTKENEWERKCQYTLENIQKTNGRTLVLFRTTQELAAFKEYVSKEQMSVPFLYEGDQEISQLVSRFQNEEETVLCAVHLWEGLDIPGSSLSHVIIWSLPFPPNDPVFEAKRKHVNDPFWDVDVPYMILRLRQGIGRLIRTSEDKGAISIFLSDSEDEKVVAAVKNVLPVEGKEL
>NZ_CP015250.1|WP_069355319.1|1747669_1749187_+|carboxypeptidase
MTVATYEVEKQFLTYVKKIQNYGEALSLMFWDLRTGAPKKGVDQRSEVIGMLSSEVFAMSTSDEMGNYLTELEALIREDKLSETTTKMVEECRKEYDRNKKIPQAEYEAYVKLEAKAESVWEEAREKSDFEMFRPYLEKIVEFKKKFITYWGYETYKYNTLLDMYEPGITVEVLDHVFGQLRERIVPLVKEISESKKGLKTSALSEQFSKEKQKNFTLELLKQLNYDFEAGRLDETVHPFEITLNRGDVRITTRYDEKDFRMAVFGTIHECGHAVYEQNIAEQFEGTPLCSGTSMGIHESQSLFFENFIGRNKSFWKKNYDLLKEYSDGQFDDMSVDEFYDAINESKPSFIRIEADELTYPLHVMVRYELEKELFDGTLQVKDLPAAWNDKMEAYLGIRPENDAQGVLQDVHWAGGSFGYFPSYALGYMYAAQFKQRMLKDIPNFDALLEEGNVTPIREWLTEHIHQYGKTKKPLEILEDVTGEGLNANYLADYLEAKYRAIYEL
>NZ_CP015250.1|WP_069355320.1|1749235_1749709_+|GNAT-family-N-acetyltransferase
MGYTYTVMKQEEAEEIAYNWHYEGKYSFYDIKADEEDLAEFLHGESRGDHTFSVKQNGILIGFFTVCKMNDGTVDIGLGMRPDITGNGFGLQFVNAGLAFSKEKYGCKYITLSVATFNERAIKVYKRAGFEVVGTFIQKTNGSCFEFLKMNYICKRD
>NZ_CP015250.1|WP_044307511.1|1749868_1750615_+|type-I-methionyl-aminopeptidase
MITIKTKNEIDLMHESGKLLASCHKEIAKMIKPGITTQEINTFVEMYLKKHGATSEQKDYNGYPYAICASVNDEMCHAFPADVPLTEGDIVTIDMVVNLNGGLSDSAWTYRVGKVSDEAEKLLLVAENALYKGVDQAVIGNHVGDIGYAIESYVTNEGFSVARDFTGHGIGKEIHEEPAIFHFGKQGQGPQLQEGMVITIEPIVNVGMRYSKVDLNGWTARTMDGKLSAQYEHTLAITKDGPIILTKL
>NZ_CP015250.1|WP_000866496.1|1750940_1751534_+|xanthine-phosphoribosyltransferase
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPSVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDENDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGVRVESLAEIASLDNGTVTFVQQETAEVK
>NZ_CP015250.1|WP_000809230.1|1751537_1752860_+|xanthine-permease
MKQHPFKIASLGMQHMLAMYAGAIIVPLIVGGGLGLNQKELTYLVSIDLLMCGVATILQALSNRFFGIGLPVVLGCTFTAVGPMIAIGKQYGVSSIYGAIIAAGLFVVIFAKLFGKLVKLFPPVVTGSVVTVIGVTLVPAAINDMAGGVGSKDFGSLENLALAFGVLLFIIIMYRFFDGFIRSISILLGLLFGTIVAAFMGKVSLQAVGEADWFHGIQPFYFGTPTFELTPVITMILVACVGIVEATGVYFALSDICNKKIGEKELTKGYRAEGLAMVLGGIFNAFPYTTYSQNVGLVQLTGVRNRVIIYTCGGMLIVLGFIPKIAAITTIIPKSVLGGAMLAMFGMVMAYGIKMLSSVDFGKQENLLIVACSVGIGLGVTVVPTLFSQLPENIRILTDNGIVLGSASAVLLNIVFNMVPQRKVKVKEEPVSMQSAVREA

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Crispr_ID: NZ_CP015250_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_3

3318164-3318272

Orphan

Consensus_repeat	Method
TATATCAACGATTTTTCAAATATATCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015250_3

>merge|NZ_CP015250|3|3318164-3318272|CRISPRCasFinder
TATATCAACGATTTTTCAAATATATCGTTCATTACTTACAATATATCAACGATTTTTCAAATATATCGATCGTAACTTGCAGTATATCAACGATTTTTCAAATATATCG

>NZ_CP015250|3|1|3318164-3318272|CRISPRCasFinder
TATATCAACGATTTTTCAAATATATCG	TTCATTACTTACAATATATCAACGATTTTTCAAATATATCGATCGTAACTTGCAG
TATATCAACGATTTTTCAAATATATCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_000444089.1\|3300473_3301160_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP015250.1\|WP_069355916.1\|3318399_3319632_-\|DUF4073-domain-containing-protein	unknown	unknown	gnl\|CDD\|290024
NZ_CP015250.1\|WP_069355911.1\|3302600_3303029_-\|DUF5412-domain-containing-protein	unknown	unknown	gnl\|CDD\|375187
NZ_CP015250.1\|WP_069355923.1\|3327200_3328460_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP015250.1\|WP_069355913.1\|3305902_3309100_-\|bifunctional-P-450/NADPH--P450-reductase	unknown	unknown	gnl\|CDD\|223446
NZ_CP015250.1\|WP_001046608.1\|3317006_3318002_-\|D-cysteine-desulfhydrase	unknown	unknown	gnl\|CDD\|179673
NZ_CP015250.1\|WP_069355917.1\|3319958_3320918_-\|RNA-splicing-ligase-RtcB	unknown	unknown	gnl\|CDD\|376465
NZ_CP015250.1\|WP_000005108.1\|3309834_3311313_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP015250.1\|WP_069355919.1\|3322692_3323274_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379324
NZ_CP015250.1\|WP_000636463.1\|3301350_3302292_-\|class-A-beta-lactamase	unknown	unknown	gnl\|CDD\|185339
NZ_CP015250.1\|WP_069355920.1\|3323424_3324537_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP015250.1\|WP_069355922.1\|3325257_3326322_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP015250.1\|WP_069354853.1\|3315172_3316318_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP015250.1\|WP_069355921.1\|3324586_3325258_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP015250.1\|WP_000916241.1\|3321200_3321419_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376465
NZ_CP015250.1\|WP_069355915.1\|3312714_3314505_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NZ_CP015250.1\|WP_084746166.1\|3321556_3322477_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|377216
NZ_CP015250.1\|WP_069355914.1\|3311740_3312334_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_053565487.1\|3326507_3327131_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238042
NZ_CP015250.1\|WP_069355912.1\|3303579_3305691_+\|TerD-family-protein	unknown	unknown	gnl\|CDD\|132992

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_000444089.1\|3300473_3301160_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.65915e-88
NZ_CP015250.1\|WP_069355916.1\|3318399_3319632_-\|DUF4073-domain-containing-protein	gnl\|CDD\|290024	pfam13285, DUF4073, Domain of unknown function (DUF4073). This family is frequently found at the C-terminus of bacterial proteins carrying the family, Metallophos pfam00149.	1.75259e-101
NZ_CP015250.1\|WP_069355911.1\|3302600_3303029_-\|DUF5412-domain-containing-protein	gnl\|CDD\|375187	pfam17428, DUF5412, Family of unknown function (DUF5412). This is a family of unknown function found in Bacteria. Members of this family have one or two predicted trans-membrane regions.	1.91256e-52
NZ_CP015250.1\|WP_069355923.1\|3327200_3328460_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.06355e-60
NZ_CP015250.1\|WP_069355913.1\|3305902_3309100_-\|bifunctional-P-450/NADPH--P450-reductase	gnl\|CDD\|223446	COG0369, CysJ, Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism].	1.78941e-171
NZ_CP015250.1\|WP_001046608.1\|3317006_3318002_-\|D-cysteine-desulfhydrase	gnl\|CDD\|179673	PRK03910, PRK03910, D-cysteine desulfhydrase; Validated.	0
NZ_CP015250.1\|WP_069355917.1\|3319958_3320918_-\|RNA-splicing-ligase-RtcB	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	1.77162e-59
NZ_CP015250.1\|WP_000005108.1\|3309834_3311313_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.5603e-109
NZ_CP015250.1\|WP_069355919.1\|3322692_3323274_+\|AAA-family-ATPase	gnl\|CDD\|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	1.81256e-10
NZ_CP015250.1\|WP_000636463.1\|3301350_3302292_-\|class-A-beta-lactamase	gnl\|CDD\|185339	PRK15442, PRK15442, beta-lactamase TEM; Provisional.	4.64828e-61
NZ_CP015250.1\|WP_069355920.1\|3323424_3324537_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	1.10353e-13
NZ_CP015250.1\|WP_069355922.1\|3325257_3326322_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.22532e-09
NZ_CP015250.1\|WP_069354853.1\|3315172_3316318_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.55043e-25
NZ_CP015250.1\|WP_069355921.1\|3324586_3325258_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.42083e-102
NZ_CP015250.1\|WP_000916241.1\|3321200_3321419_-\|hypothetical-protein	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	6.57794e-05
NZ_CP015250.1\|WP_069355915.1\|3312714_3314505_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	9.92976e-69
NZ_CP015250.1\|WP_084746166.1\|3321556_3322477_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|377216	pfam04072, LCM, Leucine carboxyl methyltransferase. Family of leucine carboxyl methyltransferases EC:2.1.1.-. This family may need divides a the full alignment contains a significantly shorter mouse sequence.	2.03029e-59
NZ_CP015250.1\|WP_053565487.1\|3326507_3327131_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	7.11682e-12
NZ_CP015250.1\|WP_069355912.1\|3303579_3305691_+\|TerD-family-protein	gnl\|CDD\|132992	cd06974, TerD_like, Uncharacterized proteins involved in stress response, similar to tellurium resistance terD. Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.	1.44056e-14

>NZ_CP015250.1|WP_001046608.1|3317006_3318002_-|D-cysteine-desulfhydrase
MNLAKFPRKKYTESYTPIEKLNNFSEALGGPTIYFKRDDLLGLTAGGNKTRKLEFLVADAQEKGADTLITAGGIQSNHCRLTLAAAVKEKMKCILVLEEGLEPEEKRDFNGNYFLYHLLGAENVIVVPNGADLMEEMNKVAKEVSEKGSTPYVIPVGGSNPTGAMGYVACAQEIMAQSFEQGIDFSSVVCVSGSGGMHAGLITGFSGTQSHIPVIGINVSRGKAEQEEKVAKLVDETSAHVGIPNFISRDAVTCFDEYVGPGYALPTPEMVEAVQLLAKTEGILLDPVYTGKAVAGLIDLIRKGKFNKEDNILFVHSGGSPALYANTSLFA
>NZ_CP015250.1|WP_069354853.1|3315172_3316318_-|IS110-family-transposase
METLHSHCAGLDVHQKEIVVCTYIGNSETELTKEIRTFPTLTKHLFEMLQWLEELHITHLAMESTGIYWKPVFNILEDYFDITLANAQRIKNVPGRKTDVADAEWIAKLLRYGLIEKSFVPPSDIRELRDLTRLRKKMIGNMTAEKNRIQKTLECSNIKLGSIISDVFGVSGRKLLTRLVEQGYVNSHEVEENIHGSMMPKASQITESLFGTLNPHQIFLIRQSWNHILFLEESIQQIEEKIDQLLSIYQEQVELLLTIPGVKKHAAASIIAEVGVEMRQFPSAQHLASWAGLSPGNHESAGKKKNSRTTKGNPHIQSMLCEVAWAISRTRHTWLSGKYWSLAARRGKKKALIAIAHKVIKIIYHILDQRSGFIEYSKVLS
>NZ_CP015250.1|WP_069355915.1|3312714_3314505_-|S9-family-peptidase
MIQFPMEDAEQFFRSYSIGRFTVSEDEGKLIFSTNLNGHSNLWAMDLPNLSPYPLTYCNQSSNFIKMDSLNRFILAGFDKDGDENYHIYALKPEGGGLLELIPAGETEKDYFVHLTEDGERLYYVTSKDNPMFLNSRCYNIRTKEDTLLLTGVETPTYVEAVSPNESSYIVLKSYSNTYNVGYVKKGEELICLVPSSEKEHTVGSISYIDENTVIFVTNYEEEFSYVASFDLNKQEFKPICKIEKEDISDIKWHAETKNGYIVSSKGVTDRLYKFVWDKKELILLNSPVDTISQIEITKSENLYLLGESATKTANIYYKKNRDTEWAALTKNYVIGLSESSFVEPDVITYASFDGLNIEALLFRAKGEVQNGYTIFWPHGGPQSAETKDFRALFQYLLRQGYNIFAPNFRGSTRYGSTFTKMIEGDWGEAPRLDCVAGIEWLFEQGISTPDKLFVMGGSYGGYMTLLLHGRHSEYFRAAIDIFGPSNLFSFIESMPENWKPLAVNLIGDINNDKDKLIQDSPITYLNQMNKPLLIIQGANDPRVVKEESDQIFHALQEQGVDVEYLVLDDEGHGFSKKENEIYVYRRITEFLAKHK
>NZ_CP015250.1|WP_069355914.1|3311740_3312334_+|hypothetical-protein
MDQYWYLNSKGNGEQYTNQISLYSQPEITKSEVMNDLKLPENWSYRVYPVSWDSPANYTGFSPQPPPFSWGQPINYAGMMPQGHPDNWTPLPGHAGFNFQKPSFPWAQPFNHTGMFAQGHLAALLSPPTKPFHFNTNNSGVFGNPPGWGSPWAPMGWGNNGGNGQPGMLGNLLTAGKGTMNGIGMISSLIGMGKFFF
>NZ_CP015250.1|WP_000005108.1|3309834_3311313_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MSETLHKRKPPYLMLVILFIGAFVSFLNNSLLNVALPSIMKDLNIQDYSTIQWLSTGYMLVSGILIPASAFLITRFSNRSLFITSMVIFILGTALAAVAPNFGLLLTGRMVQAAGSSVMGPLLMNIMLVSFPREKRGTAMGIFGLVMITAPAIGPTLSGYIVEYYDWRLLFEMILPLAIISLLLGIWKSENVMKQNKNAKLDYLSLLLSSVGFGGLLYGFSSASSDGWTNKFVLTTLIIGAIALIAFIIRQLKMDEPLLDLRVYKYPMFALASVIAIVNAVAMFSGMILTPAYVQNVRGISPLSSGLMMLPGAVIMGIMSPITGKLFDKYGPRILGIVGLSITAVSTYMLASLQIDSSHTHIILIYTLRMFGMAMVMMPLMTNGLNQLPTRLNPHGTAVNNTAQQVSGSIGTAILVTIMNSVTKTKAESLMSHIDPTTFTETTKAIVTQKALLSGIQYSFYVALGMNVVALLLVFFVKRVDTSAEAVEKLNR
>NZ_CP015250.1|WP_069355913.1|3305902_3309100_-|bifunctional-P-450/NADPH--P450-reductase
MEKKVSAIPQPKTYGPLGNLPLIDKDKPTLSFIKIAEEYGPIFQIQTLSDTIIVVSGHELVAEVCDETRFDKSIEGALAKVRAFAGDGLFTSETHEPNWKKAHNILMPTFSQRAMKDYHAMMVDIAVQLVQKWARLNPNENVDVPEDMTRLTLDTIGLCGFNYRFNSFYRETPHPFITSMTRALDEAMHQLQRLDIEDKLMWRTKRQFQHDIQSMFSLVDNIIAERKSNGNQEENDLLSRMLNVPDPETGEKLDDENIRFQIITFLIAGHETTSGLLSFAIYFLLKNPDKLKKAYEEVDRVLTDPTPTYQQVMKLKYIRMILNESLRLWPTAPAFSLYAKEDTVIGGKYPIKKGEDRISVLIPQLHRDKDAWGDNVEEFQPERFEELDKVPHHAYKPFGNGQRACIGMQFALHEATLVMGMLLQHFELIDYQNYQLDVKQTLTLKPGDFKIRILPRKQTISHPTVLTPTEDKLKNAEIKQHVQKPPSIIGADNLSLLVLYGSDTGVAEGIARELADTASLEGVRTEVVALNDRIGSLPKEGAVLIVTSSYNGKPPSNAGQFVQWLEELKPDELKGVQYAVFGCGDHNWASTYQRIPRYIDEQMAQKGATRFSKRGEADASGDFEEQLEQWKQSMWSDAMKAFGLELNKNMEKERSTLSLQFVSRLGGSPLARTYEAVYASILENRELQSSSSDRSTRHIEVSLPEGATYKEGDHLGVLPVNSEKNINRILKRFGLNGKDQVILSASGRSINHIPLDSPVSLLDLISYSVEVQEAATRAQIREMVTFTACPPHKKELEALLEEGVYHEQILKKRISMLDLLEKYEACEIRFERFLELLPALKPRYYSISSSPLVAHNRLSITVGVVNAPAWSGEGTYEGVASNYLAQRHNKDEIICFIRTPQSNFELPKDPETPIIMVGPGTGIAPFRGFLQARRVQKQKGINLGQAHLYFGCRHPEKDYLYRTELENDERDGLISLHTAFSRLEGHPKTYVQHLIKQDRINLISLLDNGAHLYICGDGSKMAPDVEDTLCQAYQEIHEVSEQEARNWLDRVQDEGRYGKDVWAGI
>NZ_CP015250.1|WP_069355912.1|3303579_3305691_+|TerD-family-protein
MKNSIYIRRSLKVIIKREENKLPNIYLATVLKNLESLGFTFSEPLIEELQTLSVDAFTSFYKELVKHLKEMVGAHIQFTPMYPNFPQQMMDLSDADLYINAVIHYVTLRLPVSKVEERLPLLDSVDLKVIDLGSEEDFNQMISQLISANSSISSTDKTDVEWAITHTEDVSCFLPNVIPHKENMSFIIGVLLINRKISADAAAKYFKTATDVLRLAVALSEGDVSLASSVRFKKFNRAERRFLLGLLEQCGNITEDMIRYKKRWIRLGEILHPAEYHTRFPKTHRAFEMLRNNIKVETFNGKIEAALLNRDIMTAKNLLKTRPGEFARRLDHLIRLCSNKSTDVFNILEDFLSIIGNVSTPVLLQLTAHFKHRNDKNEFRTFFPKGNVAKAIGIENTLPFISEDICLMIVKMCEDTLKNRFTELPSLGKVFLDEQLKNHLVPFSQRSASKALRTLSRGSKVDLPEGDTIRFFLWWKEGYVNGQHTGRVDIDLSAAMYDEDWQYKEHVSFTNLRSKNFKAYHSGDITSAPKGASEFIDFDIPSVLKYGGRYVVMTLLSYTDQPYKDLPECFTGWMVRQYPGSGEVFEPSTVQDKVDITADTQISIPVILDLKERKLIWTDLSLTRDLTYDNTIEANQKGMILVGKALTNLVKPNLYDLFRLHIEARGELVQEIEEAESIFSLDKGITPFDIEKIISDFIADRQD
>NZ_CP015250.1|WP_069355911.1|3302600_3303029_-|DUF5412-domain-containing-protein
MSIINTKGEIKKTKRKVLLTILTMLVIIIGFGYWKLFSLQGVPKGELIRTVKSPDGKYLIKTYFHNAGSLSADAVRGELVNLDTDSEKNIYWNYPDTDPYIEWVNKNIVRIGDQTLDVSQKETYNWRDDDKHVKEMPKQFSR
>NZ_CP015250.1|WP_000636463.1|3301350_3302292_-|class-A-beta-lactamase
MIVLNKFFNILHYKKMVPVVFLSCATLIGCSDGNTQSELPKQTNQTKQETTGNDSFAKLEKEFDAKLGIYALDTDTNQTVTYQSDKRFAYASTHKALAVGVLLQKKSIEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGPSEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRDLLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNHDKEDAKYDDKLIAEATKIALGVLKAKNK
>NZ_CP015250.1|WP_000444089.1|3300473_3301160_-|response-regulator-transcription-factor
MESKILIVDDDKEIRNLISVYLENEGLKTQKVEDAIQALQLLEEKEFDLIILDIMMPNMDGIEACMKIREDRNMPIIMLSAKSEDIDKIQGLASGADDYLSKPFNPLELIARVKSQLRRFKKYNTSIEHNKSILEIGDLTVNTDTRQVWVRGKETRLTPKEFAILELLARNKGIVLSVAKIYEAVWKEVFYKSDNTVMVHITKIRDKIEEDSKHPIYIKTVWGIGYKI
>NZ_CP015250.1|WP_069355916.1|3318399_3319632_-|DUF4073-domain-containing-protein
MKKTVALLAVMTALLPTFSAHAEGKEQVRKSATTFNVISDIQGDLGDFDHVLKDMNKVTPLSRALIMNGDITPTGQQSQYDDVKRVLNKNKHPENVWSTVGNHEFYAGKWTADGKLSQSTWPNGVTEETLFGRYLQFSGQEKVYHKKELDGYPLLFLGTEKYMKYHDSKMWDEVYMSDEQLGWLKQNLEEYSQKDKNKPIFIFSHHVLPDTVSGSRQSPYLQDYLNVDKLYDILKDYPQVVFFTSHTHWDLNLPDWAGKKKITGGDEKGFTVVNTGGIETGWMSAGPNGGEKTAPDGYSFKQGLQVKAYGNDVIVTAYDYKRDKDIKKLLISDSKIAQMAPNVTADDSKNIIVGATEYMEYSIEGTNEWHTYSKANPPNFDGDKVVYVRHKGEMNLEPGLTQLLRFSVNK
>NZ_CP015250.1|WP_069355917.1|3319958_3320918_-|RNA-splicing-ligase-RtcB
MEVVMINKKKEEINFDHLDETIRKFVPSGFRIRDKEHRFSKMIDFDSVRAPFTLQRAQKSIGTLGGGNHFVELNEDDKGNVYIVIHSGSRNLGKQVAEYYQNFAYEQLINVKSIKEEIIERLTKEGRQQEIHEALREIKKPVIRKELAYLEGQGFKDYMNDMKIAQKYAELNRKAMTDEIVTKMDWKVTDQFTTIHNYIDMDNMILRKGAISAQKDERVIIPINMRDGSIIAFGKGNPDWNFSGPHGAGRIMSRKKAKEVLNLEDFQNTMTEVWTTSVAESTLDEAPMVYKPMDEIIQNTKETIDIKHIIKPIYNFKAN
>NZ_CP015250.1|WP_000916241.1|3321200_3321419_-|hypothetical-protein
MLKLQGKYNEAKVFTTNVEKTAAGQIIDLCNQQFVKDSKIRIMPDTHAGAGCTIGTTMTIQDKIVPNLVGVN
>NZ_CP015250.1|WP_084746166.1|3321556_3322477_-|class-I-SAM-dependent-methyltransferase
MCVKQGEASVTSLVSAFGRAYHSEFDNPKIFDDYVAKDFISQKERNNIETNMVQGIHFFNTDIAEQFQDNPKEILNWITQVQLSPTPLARAAYCERVLLHEITLGTKQYVILGAGLDTFSFRHRELENKIEIFEVDHPSTQVFKKERIKETELEVPKNLHFVSMDFTKGFSYEQLRNEGFEHKKTFFSLLGVTYYLTKEELASLLECLFEMVPAGSSIVFDYPDENLFTEKGLSNRVENMVKMAAVGGEPMKSCYSYAEMEALLEKAGLLIYEHLSPEDIDVLYFEGRNDYLEAFETVHYVHAVKR
>NZ_CP015250.1|WP_069355919.1|3322692_3323274_+|AAA-family-ATPase
MKRLIIITVGKTHSGKTTFARALEKELPHSFVMDQDNQAEFINTHYEKLQPTEGSNTLKHSLSKFIVDYAKEHTNLHLIICNSNRSLNGRMYLLNELFKKEEYIRVLVHFDIPDDVLYERVALSKRSTNIFRGNYSSFKEVLHRQQVESLHEDVVDPIENEADYLFVIRNSKDVNSTILKIVHLAKEFSPTPK
>NZ_CP015250.1|WP_069355920.1|3323424_3324537_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKTKQTIAASTLALAMIAGANSAHAEVNDATPQQSTGDRLAEIKQHKQELDAKLQQHKENVDQTLNELNKVKENVDTKVNELHERKQVADEKINEVKQHKQELDAKLQQDKQIAEDKIAEIKEHKKQVEDKVAEVKEHKQNIDNKVNEIKEHKQTVDEKVNEMKQHKENIDQKVNELKEVKKQVDEKLAELKKAKQTAEDKLAELKENKPNTGNTLEELKKIKGNLDSLSANLELAKQDVKNKLAELQKAREDLLNKINEIKQSKQTVSDDFTKKKQDLDIKINDFKHTEKKIDDKLAELHTTKQNVDNKINEVSQSKQTQADNGTKNNNAKELPNAGSEQSNNMALGMLSVLGGILLLTRNKIKTLFSK
>NZ_CP015250.1|WP_069355921.1|3324586_3325258_-|ABC-transporter-ATP-binding-protein
MTSLLKLDKVSKVYGEGNTEVTALHPMSLNVKAGEFIGIVGPSGSGKSTLLSIAGALLSPSKGDIYIREQNITKLSEKEMTDIRLKKIGFIFQFANLVPYLNVKEQLLYIAKLKKENKQDSEKRADHLLAAFGLGERKNHYPNQLSGGEKQRVAIARAFMNNPDLILADEPTASLDSKRAREVVEMMKREVKESQKAAIMITHDERMLDVCDRILTLRDGQLI
>NZ_CP015250.1|WP_069355922.1|3325257_3326322_-|ABC-transporter-permease
MFLALRELKQSKLRYGLIGLIMVLLSFLVLVISGLANGLSYDNASSIQNMEANKFVLADDAENKLLRSQIKKDDVDNVVSQVGEKEAVPFRVKVSTYEKKDSSKKVDIAIFSSERDSFLEPNIVKGEKLGTANNEMVADESIKEKGIDIGDTIIDPVSKKEFTIVGFTKDQMFSHTPVVYVNEDVWGAISQPNQKDYSAIALNTDKEVKNAHVIDKKEVLQSIPGFKEEQGTLTMIIAFLLVIAALLIGVFFYVITLQKTQQLGVLKAIGTKNSYLANSLVVQALFLSVVAMVISIVLVQGLEQILPAGMPFLLTTPMIAQYAAIFIVISILGTLISLYQVLKVDALEAIGGGM
>NZ_CP015250.1|WP_053565487.1|3326507_3327131_+|helix-turn-helix-domain-containing-protein
MKPVLTLTTYSQLKALSDPLRAEMMIRLCERPYTGQLLSEKFGISRAKIHYHLKELEKNGLIEIVYTEEKNGIIQKFYQSVAKGFTPATDLLPHLEILSESGRQIFLQMIERTKSQILAAPEEAFTLRNASEDPAKWNYVSSCWEFDATPEQFQVWVKKFYELMAELNEITKGADKDPNSKPYYISTTALQIAERTMQQFIKKEEKS
>NZ_CP015250.1|WP_069355923.1|3327200_3328460_+|MFS-transporter
MDILKNRNFLLLFLGRIFTNIGDSLYYVAAMWLVYKLSGNPFYSGLAGSLTLLPSALQFLTGPFVDRWSIKNTLVITQVLQCILILIIPITHYFDLLTVQLLLIIMPIVAFIEQFAYPAQSKALPLLLHKTQLLKGNSLFSFAYQGIDLICTTLSGILVALFGAITLYVIDSFTFAITALLFVSLKMPKQTEANTVLSTKQYFTDLKEGFSIVFRSLMGVFLIGSVVANFSIGMTMAILPSFADSLGGVRLYGFFLAAISAGCLIGALFSSWVGKHNVGRVSIISFATGAFFWFLSTVVPFQWLSIFLFGLAWISIGATNILFATIGQIVIPNQYLGRINSVTRSMGTIAMPLGSLIGGYTANVYSSQLIFALASIGILFISLVWLLHPKLRALPKADEITADTFELRFKEERGKGAAL

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Crispr_ID: NZ_CP015250_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_4

3469632-3469740

Orphan

Consensus_repeat	Method
AGTACCGTAAAGCTTGTCTCTCTCTTACATGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015250_4

>merge|NZ_CP015250|4|3469632-3469740|CRISPRCasFinder
AGTACCGTAAAGCTTGTCTCTCTCTTACATGTACTATTATGAAATATATTCAATACAATGAATAGTACGTACTTTAAAGTACCGTAAAGCTTGTTTCTCTCTTACATGT

>NZ_CP015250|4|2|3469632-3469740|CRISPRCasFinder
AGTACCGTAAAGCTTGTCTCTCTCTTACATGT	ACTATTATGAAATATATTCAATACAATGAATAGTACGTACTTTAA
AGTACCGTAAAGCTTGTTTCTCTCTTACATGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_069355982.1\|3465925_3466999_-\|glycosyl-hydrolase	unknown	unknown	unknown
NZ_CP015250.1\|WP_000236189.1\|3477210_3477606_-\|transcriptional-regulator-Spx	unknown	unknown	gnl\|CDD\|79035
NZ_CP015250.1\|WP_000158938.1\|3464937_3465537_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP015250.1\|WP_069355984.1\|3471549_3471918_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|377753
NZ_CP015250.1\|WP_001089891.1\|3468260_3469475_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP015250.1\|WP_142245131.1\|3470534_3471050_-\|heme-degrading-domain-containing-protein	unknown	unknown	gnl\|CDD\|179430
NZ_CP015250.1\|WP_000668225.1\|3461521_3462091_-\|HAD-hydrolase-like-protein	unknown	unknown	gnl\|CDD\|284381
NZ_CP015250.1\|WP_069355981.1\|3463240_3463978_-\|GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|238348
NZ_CP015250.1\|WP_069356650.1\|3456737_3458966_-\|enhancin	unknown	unknown	gnl\|CDD\|367432
NZ_CP015250.1\|WP_069355986.1\|3476180_3476594_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP015250.1\|WP_053563934.1\|3467404_3468244_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381383
NZ_CP015250.1\|WP_000573532.1\|3476783_3476918_-\|BA3454-family-stress-response-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_043938932.1\|3470018_3470492_-\|4-oxalocrotonate-tautomerase	unknown	unknown	gnl\|CDD\|179107
NZ_CP015250.1\|WP_069355980.1\|3462150_3463248_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015
NZ_CP015250.1\|WP_069355985.1\|3474958_3475648_-\|DUF3888-domain-containing-protein	unknown	unknown	gnl\|CDD\|379024
NZ_CP015250.1\|WP_000573515.1\|3477028_3477163_-\|BA3454-family-stress-response-protein	unknown	unknown	gnl\|CDD\|274085
NZ_CP015250.1\|WP_069355979.1\|3459329_3461054_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP015250.1\|WP_000987464.1\|3475720_3476056_-\|IDEAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|197982
NZ_CP015250.1\|WP_001014163.1\|3472688_3474008_-\|septum-formation-initiator	unknown	unknown	gnl\|CDD\|273283
NZ_CP015250.1\|WP_001000104.1\|3464281_3464599_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_000236189.1\|3477210_3477606_-\|transcriptional-regulator-Spx	gnl\|CDD\|79035	PRK12559, PRK12559, transcriptional regulator Spx; Provisional.	2.13029e-77
NZ_CP015250.1\|WP_000158938.1\|3464937_3465537_-\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	2.21981e-110
NZ_CP015250.1\|WP_069355984.1\|3471549_3471918_-\|DUF1304-domain-containing-protein	gnl\|CDD\|377753	pfam06993, DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.	2.09704e-37
NZ_CP015250.1\|WP_043938932.1\|3470018_3470492_-\|4-oxalocrotonate-tautomerase	gnl\|CDD\|179107	PRK00745, PRK00745, 4-oxalocrotonate tautomerase; Provisional.	3.35171e-08
NZ_CP015250.1\|WP_069356650.1\|3456737_3458966_-\|enhancin	gnl\|CDD\|367432	pfam03272, Mucin_bdg, Putative mucin or carbohydrate-binding module. This family is the putative binding domain for the substrates of enhancin, and other similar metallopeptidases. This is not the enzymically active, peptidase, part of the proteins - see pfam13402.	1.66616e-38
NZ_CP015250.1\|WP_000668225.1\|3461521_3462091_-\|HAD-hydrolase-like-protein	gnl\|CDD\|284381	pfam06941, NT5C, 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). This family consists of several 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C (NT5C) proteins. 5'(3')-Deoxyribonucleotidase is a ubiquitous enzyme in mammalian cells whose physiological function is not known.	2.10916e-06
NZ_CP015250.1\|WP_069355981.1\|3463240_3463978_-\|GTP-cyclohydrolase-II	gnl\|CDD\|238348	cd00641, GTP_cyclohydro2, GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the precursor molecule for the synthesis of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which are essential to cell metabolism. The enzyme is present in plants and numerous pathogenic bacteria, especially gram negative organisms, who are dependent on endogenous synthesis of the vitamin because they lack an appropriate uptake system. For animals and humans, which lack this biosynthetic pathway, riboflavin is the essential vitamin B2. GTP cyclohydrolase II requires magnesium ions for activity and has a bound catalytic zinc. The functionally active form is thought to be a homodimer. A paralogous protein is encoded in the genome of Streptomyces coelicolor, which converts GTP to 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (FAPy), an activity that has otherwise been reported for unrelated GTP cyclohydrolases III.	3.21802e-82
NZ_CP015250.1\|WP_142245131.1\|3470534_3471050_-\|heme-degrading-domain-containing-protein	gnl\|CDD\|179430	PRK02487, PRK02487, heme-degrading domain-containing protein.	8.72421e-88
NZ_CP015250.1\|WP_069355986.1\|3476180_3476594_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	3.30595e-25
NZ_CP015250.1\|WP_053563934.1\|3467404_3468244_-\|aldo/keto-reductase	gnl\|CDD\|381383	cd19157, AKR_AKR5G1-3, AKR5G family of aldo-keto reductase (AKR). Bacillus subtilis glyoxal reductase (GR), uncharacterized oxidoreductase YtbE, and Bacillus aryabhattai aldo-keto reductase are founding members of aldo-keto reductase family 5 member G1-3 (AKR5G1-3), respectively. GR (YvgN, EC 1.1.1.283), also called methylglyoxal reductase, reduces glyoxal and methylglyoxal (2-oxopropanal). It is not involved in vitamin B6 biosynthesis.	0
NZ_CP015250.1\|WP_001089891.1\|3468260_3469475_-\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.71407e-112
NZ_CP015250.1\|WP_069355980.1\|3462150_3463248_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	5.75504e-136
NZ_CP015250.1\|WP_069355985.1\|3474958_3475648_-\|DUF3888-domain-containing-protein	gnl\|CDD\|379024	pfam13027, DUF3888, Protein of unknown function (DUF3888). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 111 and 149 amino acids in length.	1.39548e-16
NZ_CP015250.1\|WP_000573515.1\|3477028_3477163_-\|BA3454-family-stress-response-protein	gnl\|CDD\|274085	TIGR02344, T-complex_protein_1_subunit_gamma, T-complex protein 1, gamma subunit. Members of this family, all eukaryotic, are part of the group II chaperonin complex called CCT (chaperonin containing TCP-1) or TRiC. The archaeal equivalent group II chaperonin is often called the thermosome. Both are somewhat related to the group I chaperonin of bacterial, GroEL/GroES. This family consists exclusively of the CCT gamma chain (part of a paralogous family) from animals, plants, fungi, and other eukaryotes.	0.00485711
NZ_CP015250.1\|WP_069355979.1\|3459329_3461054_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.63636e-57
NZ_CP015250.1\|WP_000987464.1\|3475720_3476056_-\|IDEAL-domain-containing-protein	gnl\|CDD\|197982	smart00914, IDEAL, A short protein domain of unknown function. It is found at the C-terminus of proteins in the UPF0302 family. It is named after the sequence of the most conserved region in some members.	1.89878e-06
NZ_CP015250.1\|WP_001014163.1\|3472688_3474008_-\|septum-formation-initiator	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	1.01502e-141
NZ_CP015250.1\|WP_001000104.1\|3464281_3464599_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	2.6441e-28

>NZ_CP015250.1|WP_001089891.1|3468260_3469475_-|MFS-transporter
MNSYTASSSEVQTNRRSIFALLALAISAFGIGTTEFVSVGLLPSISEDLHVSVTTAGLTVSLYALGVAFGAPVLTSLTANMSRKTLLMWIMIIFIIGNGIAAVATSFTVLLIARIISALSHGVFMSIGSTIAAALVPENKRASAIAIMFTGVTVATITGAPIGTFIGQQFGWRTSFLAIVVIGIIALIANSILIPSNMKKGASVSFRDQFKLITNGRLLLVFIITALGYGGTFVTFTYLSPLLQEVTGFKANTVTIILLVYGIAIAIGNVIGGKLSNHNPIRALFYMFFIQAIILFVLTFTAPFKVAGLITIILMGLFAFMNVPGLQVYVVMLAERFVPSAVDVASAINIAAFNAGIALGAYLGGIVTNSLGLIHTAWVGGIMVVGAVILTAWSMTLEKRDQVK
>NZ_CP015250.1|WP_053563934.1|3467404_3468244_-|aldo/keto-reductase
MKNLQSKTVLSNGVEMPWFGLGVFKVEEGPELVEAIKSAIKAGYRSIDTAAIYGNETAVGEGIRAGIEATGISREELFITSKVWNADQGYEETIAAYEESLKKLKLDYLDLYLVHWPVEGKYKDTWRALETLYKEKRVRAIGVSNFQIHHLQDVIKDAEIKPMINQVEYHPRLTQKELQAFCKEQGIQMEAWSPLMQGQLLDNETLQEIAEKHGKTTAQVILRWDLQNEVITIPKSTKEHRIIANADVFNFELTKEDMEKIDALNQNHRVGPDPDNFDF
>NZ_CP015250.1|WP_069355982.1|3465925_3466999_-|glycosyl-hydrolase
MEKFILAFDRELVIAEKKDSTWSVQSQFVGANPVALASDPYDPERMYCGTFDRGLWRSKDGGSSWEAIGALPSFGEVFPANAIHMRAITAVSVSPAKGDDGNGIVYVGTEPSAMFVSKNGGDSFELLTDYRQMPSYSSWFFPQRTYTHHVKHIEIDANNPETIYTTIEVGGLIKSVDGGKTWTEEKEGNYPQDIHILKSHGDAPNRLYGVLGDSFLKEPGQEYAESNDGGKTWNYMCSGLKHHYAYQMAVNPNDPENIIIATSSNPHVAHDYNNGNCESFIYKKEKNQSWAEMNVGLPTPKGTIIPVLKATSDGTFYLFSNKGVYQSVDGGSNWTSLEIPWENSFMEQHPYEMLIIK
>NZ_CP015250.1|WP_000158938.1|3464937_3465537_-|nitroreductase-family-protein
MTKDFYTALKERRTYYGINKEVQVSDEKIKEIVEFAVKYTPSAFNSQTARLVVLFGEAHDKLWDITTETLRKVVGDGDFSGTQQKMDSFKAGYGTVLFFEDEAIVKSLQEKFAAYAENFPIWSHQASGMHQLVVWTGLEAEGLGASLQHYNPLIDDEVKQEWNVPANWKLIAQMPFGNPTAAPGEKEFQPLEERVKFHK
>NZ_CP015250.1|WP_001000104.1|3464281_3464599_+|helix-turn-helix-transcriptional-regulator
MNDSTLCPRFEKGMKFFSQRWTALIIYQLFSGSQRFCTLESSLPVSGRLLSERLKELELEGIVERKVFPETPVRIEYSLTQKGFALEAIIRGIEEWSQEWIELEE
>NZ_CP015250.1|WP_069355981.1|3463240_3463978_-|GTP-cyclohydrolase-II
MVTTDTIHMLEDKIQFIHQDGKDIYLVGPIKLPINLYGETKIFQWYSWLQCSEVTNSVEGIIKKLSSINLADMQQSSVLVYGDFENSEDALIRMHSICHTGDIFGSKRCDCGFQLKQSLQMITEHGSGALFYLANHEGRGIGLFSKAMTYLLQENGLDTVEANLNLGFEDDVRNYDDTIEVLKALRSKPVKLITNNPKKLEVLQKAGLNVTSREPLWGDISEFNEKYLQTKIQRSGHFEGGHLHA
>NZ_CP015250.1|WP_069355980.1|3462150_3463248_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MLEHELYMKLALENAKAMKGQTTPNPLVGSVIVNDNRIVGVGAHMKAGEPHAEIHAIRMAGEQARGATIYVTLEPCSHYGRTGPCAEAIVQAGIKKVVVATLDPNPLVSGRGIKILQDAGIEVLVGVCEEESKKMNEVFNKYILTKRPFVTIKSGVTLDGKIATSSSDSKWITSTEARQEVHQIRNENAAILVGANTVQKDNPSLTTRIPNGRNPIRIILDSTLRIPMEANVVTDGEAPTWIFTTSNHAAKKKKALENAGVKVFVTSGEKHINLHEMLDVLGQKGVSSLLIEGGGEVNASFIENKLMDKLILYVAPKIIGGRLAPSFVGGTGITKMQDAIEFKDISFTQVGKDYRFIGYPEYRKI
>NZ_CP015250.1|WP_000668225.1|3461521_3462091_-|HAD-hydrolase-like-protein
MKFGFDIDDTLIDLRQHAFHLYNKKLNKKVGLDVFHSLKTIEIHEAFGMTSEEGSHMWNSLLDEIYYTSCSPFPYAVETLQELEKQGHEIYYITARPKEHGEQTKKWLIEKGFPVHEDRFFYGMRDEEKIHFIQEIKLNYFFDDKPAVLETLIGKPINVYAKTTSYNQHLNIPRITSWTELGDIIKKEM
>NZ_CP015250.1|WP_069355979.1|3459329_3461054_-|methyl-accepting-chemotaxis-protein
MELLRNSKVGTKLNILIAISSIACIVLSLIGFLGLERGKSTSSNMYEDNLLPIERIGIVESNFYHVNMNFMEIMLSKDEKRMNELIREMDGIRKENDHLLKLFEAKVISTKEKELYNTFHETFNELRTQMKKAQELGKSNNEEAYAYYLKEIEPNMQKSIKSIRELILYNSNNAELLQKENNNSAQNTMIMFVSISILAILIIMLIGYIIKLTIRKPLALLQDDMEKVAAGDLTTRTPYKANNELGHIVQSFNSMLDNLQQLIANVKMTTQEVISTTEGVLQDTNRASSISNEVVQTVLEVKTKIEGQVTSIQESSSSMEEITTGVQTVAESSAVVAEVAVTTTERINIGSEVINHSILQMNSVHDVVEETSKVINKLVTHTQQIDTALAAITNIAEQTNLLALNAAIEAARAGENGKGFAVVAAEVRDLAEQSKESAKEVNHLIKSIQKDTQDTVNVMQKGQQKAVEGKEAAYKANQTFLSIMRDIDKITSQIQEVSAATEEMSAGTEEVNASLSLVSETATDVKKETLQTVNSIQSQAVSIEQISIQSNKMKEKVEELTELVSKFNITEQKG
>NZ_CP015250.1|WP_069356650.1|3456737_3458966_-|enhancin
MKRLLVIGIMYTMFFLIGNIHLHADERTNVKEITSLEEPTWIFQAGISKGKYHDRQDLGFILQRNTPLKVRQTNPNFKDKLTLRLLSNDSKNEKSIQVGNEWITIQGDTPLVPFIDTPYGEEHAVLEYQVGNESATKPLPIYKQQGSVSQFFSTWDQFDGEYALLQGESFQLFIPKKDKEIVRSLKDFQSLDELIAYYEDIFAMYDSIIGLDGSAVENKKSQNRYFLKADISGAGGAYYGTNWTANSSDSTKMWLDKLSWGTLHEIAHGYQAGFDNQGIFTGEVSNNLFGVQYQYSKYGKKADQVGWLFNFGKKEQVERNLYNALMKENKNYDDLDLRQKLILLTMAKQKAGDEAFAKMYQGYRKLASNAAFKKDDHSLPDLMNQYYSENGQVDFTPVFERWGFKLNNKQVEINRAKGYPAVTSLAYIVPESQLAKARALVDSDITINSNFEIVTNQQIASLGLKGNLHIHLNTNEIDTLKGGKIKLKEGNTVVQEKTIETTDINLQDVPNGVYTVEISGGKTDSMYHFSSYYAYVKEKDNSLTIDVNEMKVSKLVNQTIQFLGLGDDQFAELNTDLEQKQAVFTVTTKTPHSYYTDEKYASIEVFNDKGEKIYTKEMEGTNVTIVNDSISLKEGYRIKIYHDEIKKRLTSTATIINPMNKTNEFIMTKWGLKNTYLKNNPEENLMQRIDEEMEEIIGNPVLKEIPMQKLEMKKNVWMAINMLSEPQKITYINKYKDSLYNE
>NZ_CP015250.1|WP_043938932.1|3470018_3470492_-|4-oxalocrotonate-tautomerase
MPLIELNTWPTMSTEEKKEFIYNVTELTIKLLKIVPDKIQVLITELEKENWGKAGAVASDATFAEKSRVSNWETKESYDTPGRNVDGMAIIKIDIWNTFDQETKDKWVNELTQVTFKYTHAPLDKVLILIREMIPGNWGQSGVTGANADFLSRSRTF
>NZ_CP015250.1|WP_142245131.1|3470534_3471050_-|heme-degrading-domain-containing-protein
MSVWHKTIMEVKDMSTSNLNEISKQILKEEETLQFSSFTNEDALQLGLFIVETAKREGKLIAVDITKNGVQLFHFKMTGTNAENTKWIERKKRVVSLHDRSSYYMQIQSEITGISYNEKYLLNTSEYAAFGGCFPIRIKNVGVIGMITVSGLPPEEDHELVVRAVKNHLNQ
>NZ_CP015250.1|WP_069355984.1|3471549_3471918_-|DUF1304-domain-containing-protein
MEIIAAILVGIVALEHLFIMILEMFFIDSKVAKRAFKLPKHLEGDRNVAIMFANQGLYNGFLAAGLIWGLVLGLNPIGYMVQLFFVICVVAAIFGGFTSNKSIIVKQGLPAVLALVALLCMI
>NZ_CP015250.1|WP_001014163.1|3472688_3474008_-|septum-formation-initiator
MNGNTAKKIEVQAENTALKNEQYADPKKWHKQDTTWALSLFGTAIGAGVLFLPINAGSGGLLSLLLITLLAYPVMYYSHRALAKMIYASNSADEGITGTIREYFGNKASIIFNIVYFGSIYTIVLMYSVALTNTASSFIVHQLHMAEPPRAILSLVLVLGLIAILNFGQDITVKVMSMLVYPFIVSLLFIAISLIPQWNTSMLSFSAVSTASTGTGYFGTILMILPIIVFSFNHSPMISSFVVKQRATYGIEATDAKCAQIQKVCYIMTFAVVMFFVWSSALSLTPDDIKMAKEQNLSILSYLANELNSPVITIAAPIIAFVAITKSFLGHYIGAFEVMRDMIIKFGKSRGKDIEEKTIKTIILTFVVLSCWFVAYTNPSILGLIDSLSGPLVAAILCLLPMYAIQKVPVLAKYKGKMSNVFVIIVGVLTVLASIKSLF
>NZ_CP015250.1|WP_069355985.1|3474958_3475648_-|DUF3888-domain-containing-protein
MKIRLTMVSIICLFSFLLPCISAQAIVEKENDINRNFGIDLTGYELYSFGDFNQLDYKITPLTQLFLGIVQTEGEWINEPRLYIKGNKGYFHLLKADGTNVLYTVEKSGDFWRIIDVKRKKINRIPVPKKLLKEVVIELLLEPISKEVENYYKEPKLWYRGSEKILEIRKDTTNYTFYVTLQIQTFEGAHNPPYGEDTITFRIKGNDLKTIHYKHRDISEEESNKLHLR
>NZ_CP015250.1|WP_000987464.1|3475720_3476056_-|IDEAL-domain-containing-protein
MMSNNNHVLKVGDWVRGISNEGELIVGYIVSLDDVEDIVTVSIVKRDGQYTINEAILLFSKHVNKLPESKVINKEQILYLIDLALLTGDEEWFIELSSKLNSINELVNGGV
>NZ_CP015250.1|WP_069355986.1|3476180_3476594_-|Rrf2-family-transcriptional-regulator
MNSDFTLAIHSLTYLALQPDRMSTSNAISESAGVHPVRIRKVLSLLKKHKFIQSKEGTGGGFIFARDLGEVNLWHIYQITSEGALQPKCPESNNQCVVGSNMRKVLFAIFLGAEEHLGEYLKNYTMKEVVDLINQER
>NZ_CP015250.1|WP_000573532.1|3476783_3476918_-|BA3454-family-stress-response-protein
MIEVCVTVNYNDRNYQTNVIVSKDTIWTKIKQLAEEQVKKQWSV
>NZ_CP015250.1|WP_000573515.1|3477028_3477163_-|BA3454-family-stress-response-protein
MIEVCVTVNYKDRNYQTNVIVNKDTIWTKIEQLAEEQVKKQWGF
>NZ_CP015250.1|WP_000236189.1|3477210_3477606_-|transcriptional-regulator-Spx
MVILYTTASCASCRKAKAWLEEHQIDYIEKNIVSNSMTVDELKSILRLTEEGATEIISTRSKTFQDLNINIDELSLNEFYTLIIEHPLMLRRPIMLDEKRLQIGFNEEEIRKFLPRSVRTFLNIELQKLAN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015250_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_5

4824309-4824378

Orphan

Consensus_repeat	Method
CCTTGCACTCCTTGGGGACCCATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015250_5

>merge|NZ_CP015250|5|4824309-4824378|CRISPRCasFinder
CCTTGTATCCCTTGCGGACCAGTTGGACCAATATCTCCTTGCACACCTTGGATTCCTTGGGGACCTTGTA

>NZ_CP015250|5|3|4824309-4824378|CRISPRCasFinder
CCTTGTATCCCTTGCGGACCAGTT	GGACCAATATCTCCTTGCACA
CCTTGGATTCCTTGGGGACCTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_069356324.1\|4822107_4823121_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP015250.1\|WP_053563526.1\|4818696_4819212_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|349770
NZ_CP015250.1\|WP_000512463.1\|4826619_4826844_-\|spore-germination-protein	unknown	unknown	gnl\|CDD\|371190
NZ_CP015250.1\|WP_000094153.1\|4820554_4821040_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP015250.1\|WP_000180554.1\|4833629_4834052_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|212152
NZ_CP015250.1\|WP_053563527.1\|4815757_4816543_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|181585
NZ_CP015250.1\|WP_001110852.1\|4826275_4826599_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_000621772.1\|4817999_4818233_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP015250.1\|WP_000185943.1\|4818235_4818700_-\|molybdopterin-synthase-catalytic-subunit-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP015250.1\|WP_000141254.1\|4826925_4827231_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP015250.1\|WP_069356326.1\|4827660_4828785_-\|homoserine-O-acetyltransferase	unknown	unknown	gnl\|CDD\|235859
NZ_CP015250.1\|WP_069356328.1\|4832168_4833254_+\|spore-germination-protein-GerHC	unknown	unknown	gnl\|CDD\|274338
NZ_CP015250.1\|WP_016080015.1\|4821077_4822091_-\|molybdopterin-synthase-adenylyltransferase-MoeB	unknown	unknown	gnl\|CDD\|183547
NZ_CP015250.1\|WP_053563525.1\|4819181_4820471_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP015250.1\|WP_000171889.1\|4827428_4827611_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_000717656.1\|4817492_4817906_-\|DUF3888-domain-containing-protein	unknown	unknown	gnl\|CDD\|379024
NZ_CP015250.1\|WP_084746249.1\|4828937_4831082_+\|spore-germination-protein-GerIA	unknown	unknown	gnl\|CDD\|377020
NZ_CP015250.1\|WP_069356323.1\|4816556_4817414_-\|glucose-uptake-protein-GlcU	unknown	unknown	gnl\|CDD\|227309
NZ_CP015250.1\|WP_000038781.1\|4833346_4833532_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_069356327.1\|4831098_4832199_+\|GerAB/ArcD/ProY-family-transporter	unknown	unknown	gnl\|CDD\|281794

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_069356324.1\|4822107_4823121_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	5.52146e-155
NZ_CP015250.1\|WP_053563526.1\|4818696_4819212_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|349770	cd03116, MobB, molybdopterin-guanine dinucleotide biosynthesis protein B. Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In Escherichia coli, the synthesis of Moco involves genes from several loci: moa, mob, mod, moe and mog. The mob locus contains mobA and mobB genes. MobB catalyzes the attachment of the guanine dinucleotide to molybdopterin.	3.06432e-41
NZ_CP015250.1\|WP_000512463.1\|4826619_4826844_-\|spore-germination-protein	gnl\|CDD\|371190	pfam10676, gerPA, Spore germination protein gerPA/gerPF. This is a bacterial family of proteins that are required for the formation of functionally normal spores. Proteins in this family may be involved in establishing normal coat structure and/or permeability which could control the access of germinants to their receptor.	3.97675e-14
NZ_CP015250.1\|WP_000094153.1\|4820554_4821040_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.35023e-97
NZ_CP015250.1\|WP_000180554.1\|4833629_4834052_+\|hypothetical-protein	gnl\|CDD\|212152	cd11545, NTP-PPase_YP_001813558, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Exiguobacterium sibiricum YP_001813558.1 protein and its bacterial homologs. This family contains a putative NTP_PPase (YP_001813558.1) from Exiguobacterium sibiricum and its bacterial homologs. Unlike normal dimeric dUTPase-like proteins with a central four-helix bundle forming the active site, YP_001813558.1 displays a very unusual interlaced segment-swapped dimer that might be important for it to adapt to an extremely cold environment. Moreover, structural analysis and comparisons indicate that YP_001813558.1 potentially prefers to hydrolyze dCTPs or its derivatives.	1.24419e-63
NZ_CP015250.1\|WP_053563527.1\|4815757_4816543_-\|glucose-1-dehydrogenase	gnl\|CDD\|181585	PRK08936, PRK08936, glucose-1-dehydrogenase; Provisional.	0
NZ_CP015250.1\|WP_000621772.1\|4817999_4818233_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	6.9521e-22
NZ_CP015250.1\|WP_000185943.1\|4818235_4818700_-\|molybdopterin-synthase-catalytic-subunit-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	4.58146e-57
NZ_CP015250.1\|WP_000141254.1\|4826925_4827231_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.8779e-23
NZ_CP015250.1\|WP_069356326.1\|4827660_4828785_-\|homoserine-O-acetyltransferase	gnl\|CDD\|235859	PRK06765, PRK06765, homoserine O-acetyltransferase; Provisional.	0
NZ_CP015250.1\|WP_069356328.1\|4832168_4833254_+\|spore-germination-protein-GerHC	gnl\|CDD\|274338	TIGR02887, Spore_germination_protein_B3, germination protein, Ger(x)C family. Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination].	2.91538e-99
NZ_CP015250.1\|WP_016080015.1\|4821077_4822091_-\|molybdopterin-synthase-adenylyltransferase-MoeB	gnl\|CDD\|183547	PRK12475, PRK12475, thiamine/molybdopterin biosynthesis MoeB-like protein; Provisional.	0
NZ_CP015250.1\|WP_053563525.1\|4819181_4820471_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.01032e-159
NZ_CP015250.1\|WP_000717656.1\|4817492_4817906_-\|DUF3888-domain-containing-protein	gnl\|CDD\|379024	pfam13027, DUF3888, Protein of unknown function (DUF3888). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 111 and 149 amino acids in length.	1.31353e-05
NZ_CP015250.1\|WP_084746249.1\|4828937_4831082_+\|spore-germination-protein-GerIA	gnl\|CDD\|377020	pfam03323, GerA, Bacillus/Clostridium GerA spore germination protein.	0
NZ_CP015250.1\|WP_069356323.1\|4816556_4817414_-\|glucose-uptake-protein-GlcU	gnl\|CDD\|227309	COG4975, GlcU, Putative glucose uptake permease [Carbohydrate transport and metabolism].	3.5706e-118
NZ_CP015250.1\|WP_069356327.1\|4831098_4832199_+\|GerAB/ArcD/ProY-family-transporter	gnl\|CDD\|281794	pfam03845, Spore_permease, Spore germination protein.	7.96736e-94

>NZ_CP015250.1|WP_069356324.1|4822107_4823121_-|GTP-3',8-cyclase-MoaA
MQEMVKDFFGRPLQDLRISVIDRCNFRCTYCMPAEIFGPDYAFLKDEFLLTFDEIERLAKLFVNIGVRKIRITGGEPLLRKDLAKLIARLVKIDELIDIGLTTNAIHLTKQAKALKEAGLHRVNVSLDAIDDDIFKNINGRNINTKPVIKGIIAAKEAGLEVKVNMVVKKGMNDHQVLPMAAYFKEQGITLRFIEFMDVGSTNGWNFDQVVTKRELIEMIHKVYPLEPAEAHYFGEVAKRYRYVGTNVEVGFITSVSESFCGSCTRARISADGKFYTCLFATEGLNVRELLRGNLSDEELLSVIQDVWMNRKDRYSDERTEESAKNRPKIEMSYIGG
>NZ_CP015250.1|WP_016080015.1|4821077_4822091_-|molybdopterin-synthase-adenylyltransferase-MoeB
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKVTIADRDYVEWSNLQRQQLYTEEDAKQYKPKAIAAAEHLQAINSEVEINPVVTDVTVQEMEELVRDVDLILDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTILPGKTPCFRCLMEHPASGATCDTAGIIQPAVQLVVAHQITEALKILVEDFGALRETMLSFDLWNNQQMAFKVNRQKKDTCLSCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRKNFNLEEIKKRLQRSVEIKATPYLLSFPVEEYRFVLFTDGRAFIHGTNDMNVAKSLYARYIG
>NZ_CP015250.1|WP_000094153.1|4820554_4821040_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MSSFTHFNDQGRAKMVDISDKKTTVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSEEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRNS
>NZ_CP015250.1|WP_053563525.1|4819181_4820471_-|molybdopterin-molybdotransferase-MoeA
MVEKRIPIQVAEAVERVMKYAKYGEVEEISITESYGRILGEDVVSDHDVPHFDRSPYDGFAIRAEDTKGATQENPIEFEVIGEIGAGSVFLEEVGAFKAIRIMTGAAIPEECNAVVMLELTEGFEKNGKTYMKLKRPFNNGDNVSFKGEDIKQNQVLVKKGVAINPGVAALLATFGYSTVKVVKQPVVGIVTTGSELLEVHEPLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDACFTAVQLAMDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDGKLLFGLSGNPSACYVGFELFVHPIIKTYLYAKEPHVYRADAILQKDFSKPNPFTRFVRANVTIVDGALQAMPVGLDKSSAVSSLADANAFIVLPGGTRGFETGMKVSVLLLEHSEGCDWPWAKPLQSYK
>NZ_CP015250.1|WP_053563526.1|4818696_4819212_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MGKAPSILQIVGYQNSGKTTLVEKILHVLAESEMKVATIKHHGHGGFPEVAQKDSERHRKAGAVVSSVEGAGLLSLSSLRKKWSLQEIIRLYEFFEVDTILIEGYKKENYPKVVLLRSAEDVELLHKVENIVAIITWYDVPANIREEYKVFHITEEELYIDWFLQTVRSAK
>NZ_CP015250.1|WP_000185943.1|4818235_4818700_-|molybdopterin-synthase-catalytic-subunit-MoaE
MTNTYYEVIDTEISIEEVTKKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGLEVKEKWPGTYVAITHRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
>NZ_CP015250.1|WP_000621772.1|4817999_4818233_-|molybdopterin-converting-factor-subunit-1
MIRVLLFAHLQEEAGTSELQIEKENITVAELKDVVAKEYNVPVSEPIMVAINEEYANEDDRVQDGDVVALIPPVSGG
>NZ_CP015250.1|WP_000717656.1|4817492_4817906_-|DUF3888-domain-containing-protein
MKKICVIITAICSIFFSSPSDSFAKESREQLLESALLNRYYSVIRQVTEDQYECDAVINIKRLGRKDEFVPRFEVTLQFLTFQGAHNPPNDKVTLTLEDYLDHIKVKNVEREKNVSNDVVEKICARKKEKMKAHSND
>NZ_CP015250.1|WP_069356323.1|4816556_4817414_-|glucose-uptake-protein-GlcU
MDIFLAILPAIFWGSIVLFNVKLGGGPYSQTLGTTFGALIFSIVVYIFMKPVLTPTVIGVGVVSGLFWALGQANQLKSIDLMGVSRTMPISTGLQLVATTLFGVIVFHEWSTTISVVLGILALICIIVGVILTSLQSEEEKNAEQAANFKRGIIILLISTVGYLVYVVVIRLFNVDGWSALLPQAVGMVLGGILLTFKHHPFNKYAIRNIIPGLIWAAGNMFLFISQPRVGVATSFSLSQMGIIISTLGGILILGEKKTKRQLTGIVVGIVFIIAAGIMLGIAKS
>NZ_CP015250.1|WP_053563527.1|4815757_4816543_-|glucose-1-dehydrogenase
MYSDLEGKVVVITGSATGLGRAMGVRFAKEKAKVVINYRSRESEANDVLEEIKKVGGEAIAVKGDVTVESDVVNLIQSAVKEFGTLDVMINNAGIENAVPSHEMPLEDWNKVINTNLTGAFLGSREAIKYFVEHDIKGSVINMSSVHEKIPWPLFVHYAASKGGIKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPKKRADVESMIPMGYIGNPEEIAAVATWLASSEASYVTGITLFADGGMTLYPSFQAGRG
>NZ_CP015250.1|WP_001110852.1|4826275_4826599_-|hypothetical-protein
MPAHIKEFVIVNNTGNIFTGDNLSDTSFTASKSYSGSMGCTWIDVVTVIGTETKLCLQPGDSVTTTYTRGTPAGTVTGTNMGQSVNASGIAQAVPNTDNMDSIAGLP
>NZ_CP015250.1|WP_000512463.1|4826619_4826844_-|spore-germination-protein
MGINLRKVKIINNTGAVNVGDCYDISPLAVAKVYAGAGGSSAAIFLNGKRQPEAVIRTSVFLPPLATSTRTLGS
>NZ_CP015250.1|WP_000141254.1|4826925_4827231_-|rhodanese-like-domain-containing-protein
MTEVNTITTEEVQERLENGETLFLVDVREDEEVAAGKIPEAVHIKMGDIPHKVDFFNKENEYIFICRSGMRSENVCHYLNEQGFKTVNMVGGMLQYEGETK
>NZ_CP015250.1|WP_000171889.1|4827428_4827611_+|hypothetical-protein
MTLFLFIMGIVFLLAAIIALSMKNNRKINSPQEMSFLFLLLSIAFFGIAIATYIFRLQIM
>NZ_CP015250.1|WP_069356326.1|4827660_4828785_-|homoserine-O-acetyltransferase
MQIVKKEKFVLKEFAFENGREIPVQMGYETYGTLNRERSNVILVCHYFSATSHAAGKYTVHDEESGWWDGLIGPGKAIDTNKYFVICTDNLCNVQARNPYVITTGPKSINPETGEEYAMDFPVFTFLDVARMQYELIKGMGISRLHAVIGPSAGGMIAQQWAVHYPHMVERMIGVITNPQNPIITSVNVAQNAIEAIQLDPSWKDGKYGEEQPIKGLHLASRMMFMNAFDEHFYEMAFPRNSIEIEPYEKFSTLTSFEKEINTATYRSIELVDANSWMYTAKAVLLHDIAHGFSSLEESLSNIEANVLMIPCKQDLLQPSRYNYKMVDILQKQGKYAEVYEIESINGHMAGAFDIHLFEKKVYEFLNRKVSSFV
>NZ_CP015250.1|WP_084746249.1|4828937_4831082_+|spore-germination-protein-GerIA
MIWNWLRKKKKSNTPEANETDNWEQHSNNQEGDNEEQTRSMKHNKGKNNEQKDSSQDKQQSAKQEDSSQNKQQSSKQKDSSQDKQQSAKQEDSSQNKQQSSKQKDSSQGKQQSAKQEDSSQDKQQSAKQEDSSQDKQQAKQEDSSQDKQQSAKQGDSSQDKQQSAKQEDSSQDKQQSAKQEDSSQDKQQSAKQGDSSQDKKQNTKQDEPSQSKQQSSGGNSIYDFTKPEKDRIHSLQDLIEKLKKSSDFINYHTSDDETMPYWISYYRPSLDGEKLQKYLMPTLLEKPCASLEQLKEHIPMSGITITNDLQKIEDMVLKGHAIIQLNQQDQKCMLANIAIDNYRAPTPPLNESTVIGPQEGFVEDIDTNINLVRKRLPVLDLQTKEMIIGEFSKTKVVMMYLDNLAEKDNVDFLEESLRALEYDQINDSAYIQELMGEKSIFPLYINTERTDRVTKALIDGKIAIFVDGSPSVLLTPVSYFDFFISPEDYNVSWLYATFSRILRLIAVLFSICATPLYVAVLNYHYELIPSDLLETLILSRAQVPFPPLIEALFLELAIDLLREAGARLPMKVGQTLGIVGGIVIGQASVQAGLTSNILLIIVALSALASFITPIYKMGNAVRLLRFPFLMFAEIGGLFGISLGFIFLFTHLFRLTSLRKPYALFYPTRQQSVKDSWIRFPLTMIDTRDVQARPQHVKKAAKGISTKHRSDFDD
>NZ_CP015250.1|WP_069356327.1|4831098_4832199_+|GerAB/ArcD/ProY-family-transporter
MSKVQEKYQISPIFVFFLIHGAQFGAGVLGFARIIAKAAGYDGWMGVIITGIFIHILIWMMYVLLKETNGNLVDLHRQTFGKWLGNGISIIFMAYFLIVSISVIRTYVEIIQVWMFPTASTFMLTLFLCLVSYYIISSGFRVITGICVISVGGTLGYLFLSLFVLKYSHWDNLLPIFTHSFSDILKAAHLSIYSMTGFEIYLMVYPFVKKPMQSHKFAQYGALFSNLLYLFSTLLAFTFFSEKQLLKTIWAQLSMTQVIQLPFIERLEYIAISAYALVIITSFILPLWAATRGTHEIFRVKQRGVLIAFFLITVIVSQLLTNRHDINNFISNASKVSSWLIYVYIPILFIIVWVKRKWKKSKAQVN
>NZ_CP015250.1|WP_069356328.1|4832168_4833254_+|spore-germination-protein-GerHC
MEKIKSTSKLILISCITFFSLTGCLQKNIIDDVQLIQGSVFDVAKDNKVKVTFVCPIQKKGNKVQVFEGSANAVKQVKADTSLESSQPFASGQMRVALYTIRLAKTGMSTSFDTLLRDVNIGNALYAALLDGNGTELLKGKYSTSYNVAIYIKKLLEHNMETGPLPADNLHIGAFRYYQEGKDYYIPILKKHGDKIKITGIGLFKKDKYIGKIAEKDMFIFKGLLEKHKLDSHEFKTDSAYVMINNIRSVPTYDIKIKNGKPSFFIHVHLDARIQELSKQINLENNKNTKKIEKNVQKQLDIQAAKLIKQFKSLNVDPLGLGAKYKQHYRPFKLEEWRQMYKDVPVHIKYTVNITNSGVIE
>NZ_CP015250.1|WP_000038781.1|4833346_4833532_+|hypothetical-protein
MSKKLVKPILNGILFLGVFLFAHTYLKNVSFTRYLLVVIPMLLVGIFGIDLISSLLIKKEE
>NZ_CP015250.1|WP_000180554.1|4833629_4834052_+|hypothetical-protein
MTNEKGLDKGYELVAKMHEVFGHPVTNTPTKLTEERAKIRASFMQEELEEFLEATTVEDQYDALIDLIYFAFGTFAEMGVRPDKGFEIVNNANMAKLFPDGKPRFREGDGKILKPEGWQAPEPQLRAEIERQRQEAEKNC

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Crispr_ID: NZ_CP015250_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_6

4824681-4824822

Orphan

Consensus_repeat	Method
CCTTGCACTCCTTGGGGACCCATC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP015250_6

>merge|NZ_CP015250|6|4824681-4824822|CRISPRCasFinder
CCTTGTATTCCTTGAGGACCTTGCACTCCTTGTGCACCCGTCGCTCCTTGAATGCCTTGGATTCCTTGCACTCCTTGGGGACCCATCGGACCTGTTGGGCCAATCCCCCCTTGAGCACCTTGCACTCCTTGGGGACCCTCTG

>NZ_CP015250|6|4|4824681-4824822|CRISPRCasFinder
CCTTGTATTCCTTGAGGACCTTGC	ACTCCTTGTGCACCCGTCGCTCCTTGAATGCCTTGGATT
CCTTGCACTCCTTGGGGACCCATC	GGACCTGTTGGGCCAATCCCCCCTTGAGCA
CCTTGCACTCCTTGGGGACCCTCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_069356324.1\|4822107_4823121_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP015250.1\|WP_053563526.1\|4818696_4819212_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|349770
NZ_CP015250.1\|WP_000512463.1\|4826619_4826844_-\|spore-germination-protein	unknown	unknown	gnl\|CDD\|371190
NZ_CP015250.1\|WP_000094153.1\|4820554_4821040_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP015250.1\|WP_000180554.1\|4833629_4834052_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|212152
NZ_CP015250.1\|WP_053563527.1\|4815757_4816543_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|181585
NZ_CP015250.1\|WP_001110852.1\|4826275_4826599_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_000621772.1\|4817999_4818233_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP015250.1\|WP_000185943.1\|4818235_4818700_-\|molybdopterin-synthase-catalytic-subunit-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP015250.1\|WP_000141254.1\|4826925_4827231_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP015250.1\|WP_069356326.1\|4827660_4828785_-\|homoserine-O-acetyltransferase	unknown	unknown	gnl\|CDD\|235859
NZ_CP015250.1\|WP_069356328.1\|4832168_4833254_+\|spore-germination-protein-GerHC	unknown	unknown	gnl\|CDD\|274338
NZ_CP015250.1\|WP_016080015.1\|4821077_4822091_-\|molybdopterin-synthase-adenylyltransferase-MoeB	unknown	unknown	gnl\|CDD\|183547
NZ_CP015250.1\|WP_053563525.1\|4819181_4820471_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP015250.1\|WP_000171889.1\|4827428_4827611_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_000717656.1\|4817492_4817906_-\|DUF3888-domain-containing-protein	unknown	unknown	gnl\|CDD\|379024
NZ_CP015250.1\|WP_084746249.1\|4828937_4831082_+\|spore-germination-protein-GerIA	unknown	unknown	gnl\|CDD\|377020
NZ_CP015250.1\|WP_069356323.1\|4816556_4817414_-\|glucose-uptake-protein-GlcU	unknown	unknown	gnl\|CDD\|227309
NZ_CP015250.1\|WP_000038781.1\|4833346_4833532_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_069356327.1\|4831098_4832199_+\|GerAB/ArcD/ProY-family-transporter	unknown	unknown	gnl\|CDD\|281794

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_069356324.1\|4822107_4823121_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	5.52146e-155
NZ_CP015250.1\|WP_053563526.1\|4818696_4819212_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|349770	cd03116, MobB, molybdopterin-guanine dinucleotide biosynthesis protein B. Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In Escherichia coli, the synthesis of Moco involves genes from several loci: moa, mob, mod, moe and mog. The mob locus contains mobA and mobB genes. MobB catalyzes the attachment of the guanine dinucleotide to molybdopterin.	3.06432e-41
NZ_CP015250.1\|WP_000512463.1\|4826619_4826844_-\|spore-germination-protein	gnl\|CDD\|371190	pfam10676, gerPA, Spore germination protein gerPA/gerPF. This is a bacterial family of proteins that are required for the formation of functionally normal spores. Proteins in this family may be involved in establishing normal coat structure and/or permeability which could control the access of germinants to their receptor.	3.97675e-14
NZ_CP015250.1\|WP_000094153.1\|4820554_4821040_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.35023e-97
NZ_CP015250.1\|WP_000180554.1\|4833629_4834052_+\|hypothetical-protein	gnl\|CDD\|212152	cd11545, NTP-PPase_YP_001813558, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Exiguobacterium sibiricum YP_001813558.1 protein and its bacterial homologs. This family contains a putative NTP_PPase (YP_001813558.1) from Exiguobacterium sibiricum and its bacterial homologs. Unlike normal dimeric dUTPase-like proteins with a central four-helix bundle forming the active site, YP_001813558.1 displays a very unusual interlaced segment-swapped dimer that might be important for it to adapt to an extremely cold environment. Moreover, structural analysis and comparisons indicate that YP_001813558.1 potentially prefers to hydrolyze dCTPs or its derivatives.	1.24419e-63
NZ_CP015250.1\|WP_053563527.1\|4815757_4816543_-\|glucose-1-dehydrogenase	gnl\|CDD\|181585	PRK08936, PRK08936, glucose-1-dehydrogenase; Provisional.	0
NZ_CP015250.1\|WP_000621772.1\|4817999_4818233_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	6.9521e-22
NZ_CP015250.1\|WP_000185943.1\|4818235_4818700_-\|molybdopterin-synthase-catalytic-subunit-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	4.58146e-57
NZ_CP015250.1\|WP_000141254.1\|4826925_4827231_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.8779e-23
NZ_CP015250.1\|WP_069356326.1\|4827660_4828785_-\|homoserine-O-acetyltransferase	gnl\|CDD\|235859	PRK06765, PRK06765, homoserine O-acetyltransferase; Provisional.	0
NZ_CP015250.1\|WP_069356328.1\|4832168_4833254_+\|spore-germination-protein-GerHC	gnl\|CDD\|274338	TIGR02887, Spore_germination_protein_B3, germination protein, Ger(x)C family. Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination].	2.91538e-99
NZ_CP015250.1\|WP_016080015.1\|4821077_4822091_-\|molybdopterin-synthase-adenylyltransferase-MoeB	gnl\|CDD\|183547	PRK12475, PRK12475, thiamine/molybdopterin biosynthesis MoeB-like protein; Provisional.	0
NZ_CP015250.1\|WP_053563525.1\|4819181_4820471_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.01032e-159
NZ_CP015250.1\|WP_000717656.1\|4817492_4817906_-\|DUF3888-domain-containing-protein	gnl\|CDD\|379024	pfam13027, DUF3888, Protein of unknown function (DUF3888). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 111 and 149 amino acids in length.	1.31353e-05
NZ_CP015250.1\|WP_084746249.1\|4828937_4831082_+\|spore-germination-protein-GerIA	gnl\|CDD\|377020	pfam03323, GerA, Bacillus/Clostridium GerA spore germination protein.	0
NZ_CP015250.1\|WP_069356323.1\|4816556_4817414_-\|glucose-uptake-protein-GlcU	gnl\|CDD\|227309	COG4975, GlcU, Putative glucose uptake permease [Carbohydrate transport and metabolism].	3.5706e-118
NZ_CP015250.1\|WP_069356327.1\|4831098_4832199_+\|GerAB/ArcD/ProY-family-transporter	gnl\|CDD\|281794	pfam03845, Spore_permease, Spore germination protein.	7.96736e-94

>NZ_CP015250.1|WP_069356324.1|4822107_4823121_-|GTP-3',8-cyclase-MoaA
MQEMVKDFFGRPLQDLRISVIDRCNFRCTYCMPAEIFGPDYAFLKDEFLLTFDEIERLAKLFVNIGVRKIRITGGEPLLRKDLAKLIARLVKIDELIDIGLTTNAIHLTKQAKALKEAGLHRVNVSLDAIDDDIFKNINGRNINTKPVIKGIIAAKEAGLEVKVNMVVKKGMNDHQVLPMAAYFKEQGITLRFIEFMDVGSTNGWNFDQVVTKRELIEMIHKVYPLEPAEAHYFGEVAKRYRYVGTNVEVGFITSVSESFCGSCTRARISADGKFYTCLFATEGLNVRELLRGNLSDEELLSVIQDVWMNRKDRYSDERTEESAKNRPKIEMSYIGG
>NZ_CP015250.1|WP_016080015.1|4821077_4822091_-|molybdopterin-synthase-adenylyltransferase-MoeB
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKVTIADRDYVEWSNLQRQQLYTEEDAKQYKPKAIAAAEHLQAINSEVEINPVVTDVTVQEMEELVRDVDLILDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTILPGKTPCFRCLMEHPASGATCDTAGIIQPAVQLVVAHQITEALKILVEDFGALRETMLSFDLWNNQQMAFKVNRQKKDTCLSCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRKNFNLEEIKKRLQRSVEIKATPYLLSFPVEEYRFVLFTDGRAFIHGTNDMNVAKSLYARYIG
>NZ_CP015250.1|WP_000094153.1|4820554_4821040_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MSSFTHFNDQGRAKMVDISDKKTTVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSEEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRNS
>NZ_CP015250.1|WP_053563525.1|4819181_4820471_-|molybdopterin-molybdotransferase-MoeA
MVEKRIPIQVAEAVERVMKYAKYGEVEEISITESYGRILGEDVVSDHDVPHFDRSPYDGFAIRAEDTKGATQENPIEFEVIGEIGAGSVFLEEVGAFKAIRIMTGAAIPEECNAVVMLELTEGFEKNGKTYMKLKRPFNNGDNVSFKGEDIKQNQVLVKKGVAINPGVAALLATFGYSTVKVVKQPVVGIVTTGSELLEVHEPLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDACFTAVQLAMDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDGKLLFGLSGNPSACYVGFELFVHPIIKTYLYAKEPHVYRADAILQKDFSKPNPFTRFVRANVTIVDGALQAMPVGLDKSSAVSSLADANAFIVLPGGTRGFETGMKVSVLLLEHSEGCDWPWAKPLQSYK
>NZ_CP015250.1|WP_053563526.1|4818696_4819212_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MGKAPSILQIVGYQNSGKTTLVEKILHVLAESEMKVATIKHHGHGGFPEVAQKDSERHRKAGAVVSSVEGAGLLSLSSLRKKWSLQEIIRLYEFFEVDTILIEGYKKENYPKVVLLRSAEDVELLHKVENIVAIITWYDVPANIREEYKVFHITEEELYIDWFLQTVRSAK
>NZ_CP015250.1|WP_000185943.1|4818235_4818700_-|molybdopterin-synthase-catalytic-subunit-MoaE
MTNTYYEVIDTEISIEEVTKKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGLEVKEKWPGTYVAITHRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
>NZ_CP015250.1|WP_000621772.1|4817999_4818233_-|molybdopterin-converting-factor-subunit-1
MIRVLLFAHLQEEAGTSELQIEKENITVAELKDVVAKEYNVPVSEPIMVAINEEYANEDDRVQDGDVVALIPPVSGG
>NZ_CP015250.1|WP_000717656.1|4817492_4817906_-|DUF3888-domain-containing-protein
MKKICVIITAICSIFFSSPSDSFAKESREQLLESALLNRYYSVIRQVTEDQYECDAVINIKRLGRKDEFVPRFEVTLQFLTFQGAHNPPNDKVTLTLEDYLDHIKVKNVEREKNVSNDVVEKICARKKEKMKAHSND
>NZ_CP015250.1|WP_069356323.1|4816556_4817414_-|glucose-uptake-protein-GlcU
MDIFLAILPAIFWGSIVLFNVKLGGGPYSQTLGTTFGALIFSIVVYIFMKPVLTPTVIGVGVVSGLFWALGQANQLKSIDLMGVSRTMPISTGLQLVATTLFGVIVFHEWSTTISVVLGILALICIIVGVILTSLQSEEEKNAEQAANFKRGIIILLISTVGYLVYVVVIRLFNVDGWSALLPQAVGMVLGGILLTFKHHPFNKYAIRNIIPGLIWAAGNMFLFISQPRVGVATSFSLSQMGIIISTLGGILILGEKKTKRQLTGIVVGIVFIIAAGIMLGIAKS
>NZ_CP015250.1|WP_053563527.1|4815757_4816543_-|glucose-1-dehydrogenase
MYSDLEGKVVVITGSATGLGRAMGVRFAKEKAKVVINYRSRESEANDVLEEIKKVGGEAIAVKGDVTVESDVVNLIQSAVKEFGTLDVMINNAGIENAVPSHEMPLEDWNKVINTNLTGAFLGSREAIKYFVEHDIKGSVINMSSVHEKIPWPLFVHYAASKGGIKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPKKRADVESMIPMGYIGNPEEIAAVATWLASSEASYVTGITLFADGGMTLYPSFQAGRG
>NZ_CP015250.1|WP_001110852.1|4826275_4826599_-|hypothetical-protein
MPAHIKEFVIVNNTGNIFTGDNLSDTSFTASKSYSGSMGCTWIDVVTVIGTETKLCLQPGDSVTTTYTRGTPAGTVTGTNMGQSVNASGIAQAVPNTDNMDSIAGLP
>NZ_CP015250.1|WP_000512463.1|4826619_4826844_-|spore-germination-protein
MGINLRKVKIINNTGAVNVGDCYDISPLAVAKVYAGAGGSSAAIFLNGKRQPEAVIRTSVFLPPLATSTRTLGS
>NZ_CP015250.1|WP_000141254.1|4826925_4827231_-|rhodanese-like-domain-containing-protein
MTEVNTITTEEVQERLENGETLFLVDVREDEEVAAGKIPEAVHIKMGDIPHKVDFFNKENEYIFICRSGMRSENVCHYLNEQGFKTVNMVGGMLQYEGETK
>NZ_CP015250.1|WP_000171889.1|4827428_4827611_+|hypothetical-protein
MTLFLFIMGIVFLLAAIIALSMKNNRKINSPQEMSFLFLLLSIAFFGIAIATYIFRLQIM
>NZ_CP015250.1|WP_069356326.1|4827660_4828785_-|homoserine-O-acetyltransferase
MQIVKKEKFVLKEFAFENGREIPVQMGYETYGTLNRERSNVILVCHYFSATSHAAGKYTVHDEESGWWDGLIGPGKAIDTNKYFVICTDNLCNVQARNPYVITTGPKSINPETGEEYAMDFPVFTFLDVARMQYELIKGMGISRLHAVIGPSAGGMIAQQWAVHYPHMVERMIGVITNPQNPIITSVNVAQNAIEAIQLDPSWKDGKYGEEQPIKGLHLASRMMFMNAFDEHFYEMAFPRNSIEIEPYEKFSTLTSFEKEINTATYRSIELVDANSWMYTAKAVLLHDIAHGFSSLEESLSNIEANVLMIPCKQDLLQPSRYNYKMVDILQKQGKYAEVYEIESINGHMAGAFDIHLFEKKVYEFLNRKVSSFV
>NZ_CP015250.1|WP_084746249.1|4828937_4831082_+|spore-germination-protein-GerIA
MIWNWLRKKKKSNTPEANETDNWEQHSNNQEGDNEEQTRSMKHNKGKNNEQKDSSQDKQQSAKQEDSSQNKQQSSKQKDSSQDKQQSAKQEDSSQNKQQSSKQKDSSQGKQQSAKQEDSSQDKQQSAKQEDSSQDKQQAKQEDSSQDKQQSAKQGDSSQDKQQSAKQEDSSQDKQQSAKQEDSSQDKQQSAKQGDSSQDKKQNTKQDEPSQSKQQSSGGNSIYDFTKPEKDRIHSLQDLIEKLKKSSDFINYHTSDDETMPYWISYYRPSLDGEKLQKYLMPTLLEKPCASLEQLKEHIPMSGITITNDLQKIEDMVLKGHAIIQLNQQDQKCMLANIAIDNYRAPTPPLNESTVIGPQEGFVEDIDTNINLVRKRLPVLDLQTKEMIIGEFSKTKVVMMYLDNLAEKDNVDFLEESLRALEYDQINDSAYIQELMGEKSIFPLYINTERTDRVTKALIDGKIAIFVDGSPSVLLTPVSYFDFFISPEDYNVSWLYATFSRILRLIAVLFSICATPLYVAVLNYHYELIPSDLLETLILSRAQVPFPPLIEALFLELAIDLLREAGARLPMKVGQTLGIVGGIVIGQASVQAGLTSNILLIIVALSALASFITPIYKMGNAVRLLRFPFLMFAEIGGLFGISLGFIFLFTHLFRLTSLRKPYALFYPTRQQSVKDSWIRFPLTMIDTRDVQARPQHVKKAAKGISTKHRSDFDD
>NZ_CP015250.1|WP_069356327.1|4831098_4832199_+|GerAB/ArcD/ProY-family-transporter
MSKVQEKYQISPIFVFFLIHGAQFGAGVLGFARIIAKAAGYDGWMGVIITGIFIHILIWMMYVLLKETNGNLVDLHRQTFGKWLGNGISIIFMAYFLIVSISVIRTYVEIIQVWMFPTASTFMLTLFLCLVSYYIISSGFRVITGICVISVGGTLGYLFLSLFVLKYSHWDNLLPIFTHSFSDILKAAHLSIYSMTGFEIYLMVYPFVKKPMQSHKFAQYGALFSNLLYLFSTLLAFTFFSEKQLLKTIWAQLSMTQVIQLPFIERLEYIAISAYALVIITSFILPLWAATRGTHEIFRVKQRGVLIAFFLITVIVSQLLTNRHDINNFISNASKVSSWLIYVYIPILFIIVWVKRKWKKSKAQVN
>NZ_CP015250.1|WP_069356328.1|4832168_4833254_+|spore-germination-protein-GerHC
MEKIKSTSKLILISCITFFSLTGCLQKNIIDDVQLIQGSVFDVAKDNKVKVTFVCPIQKKGNKVQVFEGSANAVKQVKADTSLESSQPFASGQMRVALYTIRLAKTGMSTSFDTLLRDVNIGNALYAALLDGNGTELLKGKYSTSYNVAIYIKKLLEHNMETGPLPADNLHIGAFRYYQEGKDYYIPILKKHGDKIKITGIGLFKKDKYIGKIAEKDMFIFKGLLEKHKLDSHEFKTDSAYVMINNIRSVPTYDIKIKNGKPSFFIHVHLDARIQELSKQINLENNKNTKKIEKNVQKQLDIQAAKLIKQFKSLNVDPLGLGAKYKQHYRPFKLEEWRQMYKDVPVHIKYTVNITNSGVIE
>NZ_CP015250.1|WP_000038781.1|4833346_4833532_+|hypothetical-protein
MSKKLVKPILNGILFLGVFLFAHTYLKNVSFTRYLLVVIPMLLVGIFGIDLISSLLIKKEE
>NZ_CP015250.1|WP_000180554.1|4833629_4834052_+|hypothetical-protein
MTNEKGLDKGYELVAKMHEVFGHPVTNTPTKLTEERAKIRASFMQEELEEFLEATTVEDQYDALIDLIYFAFGTFAEMGVRPDKGFEIVNNANMAKLFPDGKPRFREGDGKILKPEGWQAPEPQLRAEIERQRQEAEKNC

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Crispr_ID: NZ_CP015250_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_7

4825023-4825172

Orphan

Consensus_repeat	Method
CCTTGCACTCCTTGGGGACCCATC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP015250_7

>merge|NZ_CP015250|7|4825023-4825172|CRISPRCasFinder
CCTTGTATTCCTTGCGGGCCCTGAAGTCCCTCTGGGCCTTCTGGACCTGTTGGTCCTATATCGCCCATTGGACCTTGTATCCCTTGAACTCCTTGTAGTCCTGTTGCTCCTGATGGCCCTGGTACTCCTTGAATTCCTTGTGGACCTTGA

>NZ_CP015250|7|5|4825023-4825172|CRISPRCasFinder
CCTTGTATTCCTTGCGGGCCCTGA	AGTCCCTCTGGGCCTTCTGGACCTGTTGGTCCTATATCGCCCATTGGACCTTGTATC
CCTTGAACTCCTTGTAGTCCTGTT	GCTCCTGATGGCCCTGGTACT
CCTTGAATTCCTTGTGGACCTTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_069356324.1\|4822107_4823121_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP015250.1\|WP_053563526.1\|4818696_4819212_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|349770
NZ_CP015250.1\|WP_000512463.1\|4826619_4826844_-\|spore-germination-protein	unknown	unknown	gnl\|CDD\|371190
NZ_CP015250.1\|WP_000094153.1\|4820554_4821040_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP015250.1\|WP_000180554.1\|4833629_4834052_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|212152
NZ_CP015250.1\|WP_053563527.1\|4815757_4816543_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|181585
NZ_CP015250.1\|WP_001110852.1\|4826275_4826599_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_000621772.1\|4817999_4818233_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP015250.1\|WP_000185943.1\|4818235_4818700_-\|molybdopterin-synthase-catalytic-subunit-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP015250.1\|WP_000141254.1\|4826925_4827231_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP015250.1\|WP_069356326.1\|4827660_4828785_-\|homoserine-O-acetyltransferase	unknown	unknown	gnl\|CDD\|235859
NZ_CP015250.1\|WP_069356328.1\|4832168_4833254_+\|spore-germination-protein-GerHC	unknown	unknown	gnl\|CDD\|274338
NZ_CP015250.1\|WP_016080015.1\|4821077_4822091_-\|molybdopterin-synthase-adenylyltransferase-MoeB	unknown	unknown	gnl\|CDD\|183547
NZ_CP015250.1\|WP_053563525.1\|4819181_4820471_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP015250.1\|WP_000171889.1\|4827428_4827611_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_000717656.1\|4817492_4817906_-\|DUF3888-domain-containing-protein	unknown	unknown	gnl\|CDD\|379024
NZ_CP015250.1\|WP_084746249.1\|4828937_4831082_+\|spore-germination-protein-GerIA	unknown	unknown	gnl\|CDD\|377020
NZ_CP015250.1\|WP_069356323.1\|4816556_4817414_-\|glucose-uptake-protein-GlcU	unknown	unknown	gnl\|CDD\|227309
NZ_CP015250.1\|WP_000038781.1\|4833346_4833532_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_069356327.1\|4831098_4832199_+\|GerAB/ArcD/ProY-family-transporter	unknown	unknown	gnl\|CDD\|281794

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_069356324.1\|4822107_4823121_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	5.52146e-155
NZ_CP015250.1\|WP_053563526.1\|4818696_4819212_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|349770	cd03116, MobB, molybdopterin-guanine dinucleotide biosynthesis protein B. Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In Escherichia coli, the synthesis of Moco involves genes from several loci: moa, mob, mod, moe and mog. The mob locus contains mobA and mobB genes. MobB catalyzes the attachment of the guanine dinucleotide to molybdopterin.	3.06432e-41
NZ_CP015250.1\|WP_000512463.1\|4826619_4826844_-\|spore-germination-protein	gnl\|CDD\|371190	pfam10676, gerPA, Spore germination protein gerPA/gerPF. This is a bacterial family of proteins that are required for the formation of functionally normal spores. Proteins in this family may be involved in establishing normal coat structure and/or permeability which could control the access of germinants to their receptor.	3.97675e-14
NZ_CP015250.1\|WP_000094153.1\|4820554_4821040_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.35023e-97
NZ_CP015250.1\|WP_000180554.1\|4833629_4834052_+\|hypothetical-protein	gnl\|CDD\|212152	cd11545, NTP-PPase_YP_001813558, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Exiguobacterium sibiricum YP_001813558.1 protein and its bacterial homologs. This family contains a putative NTP_PPase (YP_001813558.1) from Exiguobacterium sibiricum and its bacterial homologs. Unlike normal dimeric dUTPase-like proteins with a central four-helix bundle forming the active site, YP_001813558.1 displays a very unusual interlaced segment-swapped dimer that might be important for it to adapt to an extremely cold environment. Moreover, structural analysis and comparisons indicate that YP_001813558.1 potentially prefers to hydrolyze dCTPs or its derivatives.	1.24419e-63
NZ_CP015250.1\|WP_053563527.1\|4815757_4816543_-\|glucose-1-dehydrogenase	gnl\|CDD\|181585	PRK08936, PRK08936, glucose-1-dehydrogenase; Provisional.	0
NZ_CP015250.1\|WP_000621772.1\|4817999_4818233_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	6.9521e-22
NZ_CP015250.1\|WP_000185943.1\|4818235_4818700_-\|molybdopterin-synthase-catalytic-subunit-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	4.58146e-57
NZ_CP015250.1\|WP_000141254.1\|4826925_4827231_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.8779e-23
NZ_CP015250.1\|WP_069356326.1\|4827660_4828785_-\|homoserine-O-acetyltransferase	gnl\|CDD\|235859	PRK06765, PRK06765, homoserine O-acetyltransferase; Provisional.	0
NZ_CP015250.1\|WP_069356328.1\|4832168_4833254_+\|spore-germination-protein-GerHC	gnl\|CDD\|274338	TIGR02887, Spore_germination_protein_B3, germination protein, Ger(x)C family. Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination].	2.91538e-99
NZ_CP015250.1\|WP_016080015.1\|4821077_4822091_-\|molybdopterin-synthase-adenylyltransferase-MoeB	gnl\|CDD\|183547	PRK12475, PRK12475, thiamine/molybdopterin biosynthesis MoeB-like protein; Provisional.	0
NZ_CP015250.1\|WP_053563525.1\|4819181_4820471_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.01032e-159
NZ_CP015250.1\|WP_000717656.1\|4817492_4817906_-\|DUF3888-domain-containing-protein	gnl\|CDD\|379024	pfam13027, DUF3888, Protein of unknown function (DUF3888). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 111 and 149 amino acids in length.	1.31353e-05
NZ_CP015250.1\|WP_084746249.1\|4828937_4831082_+\|spore-germination-protein-GerIA	gnl\|CDD\|377020	pfam03323, GerA, Bacillus/Clostridium GerA spore germination protein.	0
NZ_CP015250.1\|WP_069356323.1\|4816556_4817414_-\|glucose-uptake-protein-GlcU	gnl\|CDD\|227309	COG4975, GlcU, Putative glucose uptake permease [Carbohydrate transport and metabolism].	3.5706e-118
NZ_CP015250.1\|WP_069356327.1\|4831098_4832199_+\|GerAB/ArcD/ProY-family-transporter	gnl\|CDD\|281794	pfam03845, Spore_permease, Spore germination protein.	7.96736e-94

>NZ_CP015250.1|WP_069356324.1|4822107_4823121_-|GTP-3',8-cyclase-MoaA
MQEMVKDFFGRPLQDLRISVIDRCNFRCTYCMPAEIFGPDYAFLKDEFLLTFDEIERLAKLFVNIGVRKIRITGGEPLLRKDLAKLIARLVKIDELIDIGLTTNAIHLTKQAKALKEAGLHRVNVSLDAIDDDIFKNINGRNINTKPVIKGIIAAKEAGLEVKVNMVVKKGMNDHQVLPMAAYFKEQGITLRFIEFMDVGSTNGWNFDQVVTKRELIEMIHKVYPLEPAEAHYFGEVAKRYRYVGTNVEVGFITSVSESFCGSCTRARISADGKFYTCLFATEGLNVRELLRGNLSDEELLSVIQDVWMNRKDRYSDERTEESAKNRPKIEMSYIGG
>NZ_CP015250.1|WP_016080015.1|4821077_4822091_-|molybdopterin-synthase-adenylyltransferase-MoeB
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKVTIADRDYVEWSNLQRQQLYTEEDAKQYKPKAIAAAEHLQAINSEVEINPVVTDVTVQEMEELVRDVDLILDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTILPGKTPCFRCLMEHPASGATCDTAGIIQPAVQLVVAHQITEALKILVEDFGALRETMLSFDLWNNQQMAFKVNRQKKDTCLSCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRKNFNLEEIKKRLQRSVEIKATPYLLSFPVEEYRFVLFTDGRAFIHGTNDMNVAKSLYARYIG
>NZ_CP015250.1|WP_000094153.1|4820554_4821040_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MSSFTHFNDQGRAKMVDISDKKTTVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSEEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRNS
>NZ_CP015250.1|WP_053563525.1|4819181_4820471_-|molybdopterin-molybdotransferase-MoeA
MVEKRIPIQVAEAVERVMKYAKYGEVEEISITESYGRILGEDVVSDHDVPHFDRSPYDGFAIRAEDTKGATQENPIEFEVIGEIGAGSVFLEEVGAFKAIRIMTGAAIPEECNAVVMLELTEGFEKNGKTYMKLKRPFNNGDNVSFKGEDIKQNQVLVKKGVAINPGVAALLATFGYSTVKVVKQPVVGIVTTGSELLEVHEPLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDACFTAVQLAMDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDGKLLFGLSGNPSACYVGFELFVHPIIKTYLYAKEPHVYRADAILQKDFSKPNPFTRFVRANVTIVDGALQAMPVGLDKSSAVSSLADANAFIVLPGGTRGFETGMKVSVLLLEHSEGCDWPWAKPLQSYK
>NZ_CP015250.1|WP_053563526.1|4818696_4819212_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MGKAPSILQIVGYQNSGKTTLVEKILHVLAESEMKVATIKHHGHGGFPEVAQKDSERHRKAGAVVSSVEGAGLLSLSSLRKKWSLQEIIRLYEFFEVDTILIEGYKKENYPKVVLLRSAEDVELLHKVENIVAIITWYDVPANIREEYKVFHITEEELYIDWFLQTVRSAK
>NZ_CP015250.1|WP_000185943.1|4818235_4818700_-|molybdopterin-synthase-catalytic-subunit-MoaE
MTNTYYEVIDTEISIEEVTKKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGLEVKEKWPGTYVAITHRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
>NZ_CP015250.1|WP_000621772.1|4817999_4818233_-|molybdopterin-converting-factor-subunit-1
MIRVLLFAHLQEEAGTSELQIEKENITVAELKDVVAKEYNVPVSEPIMVAINEEYANEDDRVQDGDVVALIPPVSGG
>NZ_CP015250.1|WP_000717656.1|4817492_4817906_-|DUF3888-domain-containing-protein
MKKICVIITAICSIFFSSPSDSFAKESREQLLESALLNRYYSVIRQVTEDQYECDAVINIKRLGRKDEFVPRFEVTLQFLTFQGAHNPPNDKVTLTLEDYLDHIKVKNVEREKNVSNDVVEKICARKKEKMKAHSND
>NZ_CP015250.1|WP_069356323.1|4816556_4817414_-|glucose-uptake-protein-GlcU
MDIFLAILPAIFWGSIVLFNVKLGGGPYSQTLGTTFGALIFSIVVYIFMKPVLTPTVIGVGVVSGLFWALGQANQLKSIDLMGVSRTMPISTGLQLVATTLFGVIVFHEWSTTISVVLGILALICIIVGVILTSLQSEEEKNAEQAANFKRGIIILLISTVGYLVYVVVIRLFNVDGWSALLPQAVGMVLGGILLTFKHHPFNKYAIRNIIPGLIWAAGNMFLFISQPRVGVATSFSLSQMGIIISTLGGILILGEKKTKRQLTGIVVGIVFIIAAGIMLGIAKS
>NZ_CP015250.1|WP_053563527.1|4815757_4816543_-|glucose-1-dehydrogenase
MYSDLEGKVVVITGSATGLGRAMGVRFAKEKAKVVINYRSRESEANDVLEEIKKVGGEAIAVKGDVTVESDVVNLIQSAVKEFGTLDVMINNAGIENAVPSHEMPLEDWNKVINTNLTGAFLGSREAIKYFVEHDIKGSVINMSSVHEKIPWPLFVHYAASKGGIKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPKKRADVESMIPMGYIGNPEEIAAVATWLASSEASYVTGITLFADGGMTLYPSFQAGRG
>NZ_CP015250.1|WP_001110852.1|4826275_4826599_-|hypothetical-protein
MPAHIKEFVIVNNTGNIFTGDNLSDTSFTASKSYSGSMGCTWIDVVTVIGTETKLCLQPGDSVTTTYTRGTPAGTVTGTNMGQSVNASGIAQAVPNTDNMDSIAGLP
>NZ_CP015250.1|WP_000512463.1|4826619_4826844_-|spore-germination-protein
MGINLRKVKIINNTGAVNVGDCYDISPLAVAKVYAGAGGSSAAIFLNGKRQPEAVIRTSVFLPPLATSTRTLGS
>NZ_CP015250.1|WP_000141254.1|4826925_4827231_-|rhodanese-like-domain-containing-protein
MTEVNTITTEEVQERLENGETLFLVDVREDEEVAAGKIPEAVHIKMGDIPHKVDFFNKENEYIFICRSGMRSENVCHYLNEQGFKTVNMVGGMLQYEGETK
>NZ_CP015250.1|WP_000171889.1|4827428_4827611_+|hypothetical-protein
MTLFLFIMGIVFLLAAIIALSMKNNRKINSPQEMSFLFLLLSIAFFGIAIATYIFRLQIM
>NZ_CP015250.1|WP_069356326.1|4827660_4828785_-|homoserine-O-acetyltransferase
MQIVKKEKFVLKEFAFENGREIPVQMGYETYGTLNRERSNVILVCHYFSATSHAAGKYTVHDEESGWWDGLIGPGKAIDTNKYFVICTDNLCNVQARNPYVITTGPKSINPETGEEYAMDFPVFTFLDVARMQYELIKGMGISRLHAVIGPSAGGMIAQQWAVHYPHMVERMIGVITNPQNPIITSVNVAQNAIEAIQLDPSWKDGKYGEEQPIKGLHLASRMMFMNAFDEHFYEMAFPRNSIEIEPYEKFSTLTSFEKEINTATYRSIELVDANSWMYTAKAVLLHDIAHGFSSLEESLSNIEANVLMIPCKQDLLQPSRYNYKMVDILQKQGKYAEVYEIESINGHMAGAFDIHLFEKKVYEFLNRKVSSFV
>NZ_CP015250.1|WP_084746249.1|4828937_4831082_+|spore-germination-protein-GerIA
MIWNWLRKKKKSNTPEANETDNWEQHSNNQEGDNEEQTRSMKHNKGKNNEQKDSSQDKQQSAKQEDSSQNKQQSSKQKDSSQDKQQSAKQEDSSQNKQQSSKQKDSSQGKQQSAKQEDSSQDKQQSAKQEDSSQDKQQAKQEDSSQDKQQSAKQGDSSQDKQQSAKQEDSSQDKQQSAKQEDSSQDKQQSAKQGDSSQDKKQNTKQDEPSQSKQQSSGGNSIYDFTKPEKDRIHSLQDLIEKLKKSSDFINYHTSDDETMPYWISYYRPSLDGEKLQKYLMPTLLEKPCASLEQLKEHIPMSGITITNDLQKIEDMVLKGHAIIQLNQQDQKCMLANIAIDNYRAPTPPLNESTVIGPQEGFVEDIDTNINLVRKRLPVLDLQTKEMIIGEFSKTKVVMMYLDNLAEKDNVDFLEESLRALEYDQINDSAYIQELMGEKSIFPLYINTERTDRVTKALIDGKIAIFVDGSPSVLLTPVSYFDFFISPEDYNVSWLYATFSRILRLIAVLFSICATPLYVAVLNYHYELIPSDLLETLILSRAQVPFPPLIEALFLELAIDLLREAGARLPMKVGQTLGIVGGIVIGQASVQAGLTSNILLIIVALSALASFITPIYKMGNAVRLLRFPFLMFAEIGGLFGISLGFIFLFTHLFRLTSLRKPYALFYPTRQQSVKDSWIRFPLTMIDTRDVQARPQHVKKAAKGISTKHRSDFDD
>NZ_CP015250.1|WP_069356327.1|4831098_4832199_+|GerAB/ArcD/ProY-family-transporter
MSKVQEKYQISPIFVFFLIHGAQFGAGVLGFARIIAKAAGYDGWMGVIITGIFIHILIWMMYVLLKETNGNLVDLHRQTFGKWLGNGISIIFMAYFLIVSISVIRTYVEIIQVWMFPTASTFMLTLFLCLVSYYIISSGFRVITGICVISVGGTLGYLFLSLFVLKYSHWDNLLPIFTHSFSDILKAAHLSIYSMTGFEIYLMVYPFVKKPMQSHKFAQYGALFSNLLYLFSTLLAFTFFSEKQLLKTIWAQLSMTQVIQLPFIERLEYIAISAYALVIITSFILPLWAATRGTHEIFRVKQRGVLIAFFLITVIVSQLLTNRHDINNFISNASKVSSWLIYVYIPILFIIVWVKRKWKKSKAQVN
>NZ_CP015250.1|WP_069356328.1|4832168_4833254_+|spore-germination-protein-GerHC
MEKIKSTSKLILISCITFFSLTGCLQKNIIDDVQLIQGSVFDVAKDNKVKVTFVCPIQKKGNKVQVFEGSANAVKQVKADTSLESSQPFASGQMRVALYTIRLAKTGMSTSFDTLLRDVNIGNALYAALLDGNGTELLKGKYSTSYNVAIYIKKLLEHNMETGPLPADNLHIGAFRYYQEGKDYYIPILKKHGDKIKITGIGLFKKDKYIGKIAEKDMFIFKGLLEKHKLDSHEFKTDSAYVMINNIRSVPTYDIKIKNGKPSFFIHVHLDARIQELSKQINLENNKNTKKIEKNVQKQLDIQAAKLIKQFKSLNVDPLGLGAKYKQHYRPFKLEEWRQMYKDVPVHIKYTVNITNSGVIE
>NZ_CP015250.1|WP_000038781.1|4833346_4833532_+|hypothetical-protein
MSKKLVKPILNGILFLGVFLFAHTYLKNVSFTRYLLVVIPMLLVGIFGIDLISSLLIKKEE
>NZ_CP015250.1|WP_000180554.1|4833629_4834052_+|hypothetical-protein
MTNEKGLDKGYELVAKMHEVFGHPVTNTPTKLTEERAKIRASFMQEELEEFLEATTVEDQYDALIDLIYFAFGTFAEMGVRPDKGFEIVNNANMAKLFPDGKPRFREGDGKILKPEGWQAPEPQLRAEIERQRQEAEKNC

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Crispr_ID: NZ_CP015250_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_8

5089273-5089372

Orphan

Consensus_repeat	Method
TAATCCAGTTCCAGTGGCTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015250_8

>merge|NZ_CP015250|8|5089273-5089372|CRISPRCasFinder
TAATCCAGTTCCAGTGGCTAGAACAGTCGGTCGTTTCACCCCTTCCTGTTCTGAGCGAGCCACCTGCACTTTTTATCTAATCCAGTTCCAGCGGCTAGAA

>NZ_CP015250|8|6|5089273-5089372|CRISPRCasFinder
TAATCCAGTTCCAGTGGCTAGAA	CAGTCGGTCGTTTCACCCCTTCCTGTTCTGAGCGAGCCACCTGCACTTTTTATC
TAATCCAGTTCCAGCGGCTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_157452921.1\|5084798_5085698_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP015250.1\|WP_069356427.1\|5099262_5099445_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_069356421.1\|5086532_5087255_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293807
NZ_CP015250.1\|WP_001096344.1\|5093280_5093427_+\|YuzL-family-protein	unknown	unknown	gnl\|CDD\|316626
NZ_CP015250.1\|WP_106823632.1\|5081785_5082985_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|133427
NZ_CP015250.1\|WP_001002981.1\|5082981_5083230_-\|spore-coat-protein	unknown	unknown	gnl\|CDD\|377935
NZ_CP015250.1\|WP_023523353.1\|5093524_5094364_+\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NZ_CP015250.1\|WP_069356426.1\|5098476_5099235_+\|TrmB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197223
NZ_CP015250.1\|WP_069356425.1\|5096289_5098290_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP015250.1\|WP_069356423.1\|5090661_5093043_-\|3-hydroxyacyl-CoA-dehydrogenase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl\|CDD\|224170
NZ_CP015250.1\|WP_069356420.1\|5085986_5086529_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP015250.1\|WP_001180555.1\|5083243_5083429_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_069356419.1\|5083572_5084286_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP015250.1\|WP_000666168.1\|5080749_5081763_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|379113
NZ_CP015250.1\|WP_069356422.1\|5087341_5089126_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173850
NZ_CP015250.1\|WP_069354784.1\|5085652_5085922_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP015250.1\|WP_069356424.1\|5095909_5096212_-\|MTH1187-family-thiamine-binding-protein	unknown	unknown	gnl\|CDD\|376658
NZ_CP015250.1\|WP_000436780.1\|5094386_5095304_-\|proline-dehydrogenase	unknown	unknown	gnl\|CDD\|223580
NZ_CP015250.1\|WP_001290600.1\|5095615_5095861_-\|YusU-family-protein	unknown	unknown	gnl\|CDD\|313925
NZ_CP015250.1\|WP_001206331.1\|5089467_5090640_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|181072

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_157452921.1\|5084798_5085698_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.19002e-31
NZ_CP015250.1\|WP_069356421.1\|5086532_5087255_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	5.2906e-71
NZ_CP015250.1\|WP_001096344.1\|5093280_5093427_+\|YuzL-family-protein	gnl\|CDD\|316626	pfam14115, YuzL, YuzL-like protein. The YuzL-like protein family includes the B. subtilis YuzL protein, which is functionally uncharacterized. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 50 amino acids in length.	1.45126e-05
NZ_CP015250.1\|WP_106823632.1\|5081785_5082985_-\|L-lactate-dehydrogenase	gnl\|CDD\|133427	cd05291, HicDH_like, L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases. L-2-hydroxyisocapronate dehydrogenase (HicDH) catalyzes the conversion of a variety of 2-oxo carboxylic acids with medium-sized aliphatic or aromatic side chains. This subfamily is composed of HicDHs and some bacterial L-lactate dehydrogenases (LDH). LDHs catalyze the last step of glycolysis in which pyruvate is converted to L-lactate. Bacterial LDHs can be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. Members of this subfamily with known structures such as the HicDH of Lactobacillus confusus, the non-allosteric LDH of Lactobacillus pentosus, and the allosteric LDH of Bacillus stearothermophilus, show that they exist as homotetramers. The HicDH-like subfamily is part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP015250.1\|WP_001002981.1\|5082981_5083230_-\|spore-coat-protein	gnl\|CDD\|377935	pfam07875, Coat_F, Coat F domain. The Coat F proteins, which contribute to the Bacillales spore coat. It occurs multiple times in the genomes it is found in.	7.47702e-15
NZ_CP015250.1\|WP_023523353.1\|5093524_5094364_+\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	1.37581e-57
NZ_CP015250.1\|WP_069356426.1\|5098476_5099235_+\|TrmB-family-transcriptional-regulator	gnl\|CDD\|197223	cd09124, PLDc_like_TrmB_middle, Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins. Middle phospholipase D (PLD)-like domain of the transcriptional regulator TrmB and similar proteins. TrmB acts as a bifunctional sugar-sensing transcriptional regulator which controls two operons encoding maltose/trehalose and maltodextrin ABC transporters of Pyrococcus fruiosus. It functions as a dimer. Full length TrmB includes an N-terminal DNA-binding domain, a C-terminal sugar-binding domain and middle region that has been named as a PLD-like domain. The middle domain displays homology to PLD enzymes, which contain one or two HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue) per chain. The HKD motif characterizes the PLD superfamily. Due to the lack of key residues related to PLD activity in the PLD-like domain, members of this subfamily are unlikely to carry PLD activity.	8.76682e-26
NZ_CP015250.1\|WP_069356425.1\|5096289_5098290_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.42825e-65
NZ_CP015250.1\|WP_069356423.1\|5090661_5093043_-\|3-hydroxyacyl-CoA-dehydrogenase/enoyl-CoA-hydratase-family-protein	gnl\|CDD\|224170	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism].	1.08136e-82
NZ_CP015250.1\|WP_069356420.1\|5085986_5086529_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.05612e-26
NZ_CP015250.1\|WP_069356419.1\|5083572_5084286_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.78596e-17
NZ_CP015250.1\|WP_000666168.1\|5080749_5081763_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	1.39354e-86
NZ_CP015250.1\|WP_069356422.1\|5087341_5089126_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	0
NZ_CP015250.1\|WP_069354784.1\|5085652_5085922_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	7.25723e-07
NZ_CP015250.1\|WP_069356424.1\|5095909_5096212_-\|MTH1187-family-thiamine-binding-protein	gnl\|CDD\|376658	pfam01910, Thiamine_BP, Thiamine-binding protein. The crystal structure of two of these members shows that this domain has a ferredoxin like fold and is likely to exists as at least homodimers. Sulphate ions are are located at the dimer interfaces, which are thought to confer additional stability. Although the function of this domain remains to be identified, its structure suggests a role in protein-protein interactions possibly regulated by the binding of small-molecule ligands. Solution of the structure of the hyperthermophilic anaerobic Thermotoga maritima sequence, UniProtKB:Q9WYV6, shows that this has a beta-alpha-beta-beta-alpha-beta ferredoxin-like fold and assembles as a homotetramer. It was possible to identify a pocket in each monmer that bound an unidentified ligand. It was also found that it bound charged thiamine though not hydroxymethyl pyrimidine. It is proposed that it is transporting charged thiamine around the cytoplasm. Under oxidative conditions this bacterium is under stress, and the transcriiptional unit within which this protein is expressed is up-regulated in these conditions, suggesting that the chelation of cytoplasmic thaimine is part of the response mechanism to such oxidatvie stress, which is mediated by this family.	2.14235e-38
NZ_CP015250.1\|WP_000436780.1\|5094386_5095304_-\|proline-dehydrogenase	gnl\|CDD\|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	4.77238e-79
NZ_CP015250.1\|WP_001290600.1\|5095615_5095861_-\|YusU-family-protein	gnl\|CDD\|313925	pfam10835, DUF2573, Protein of unknown function (DUF2573). Some members in this bacterial family of proteins are annotated as YusU however no function is currently known. This family of proteins appears to be restricted to Bacillus spp.	3.2756e-35
NZ_CP015250.1\|WP_001206331.1\|5089467_5090640_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|181072	PRK07661, PRK07661, acetyl-CoA C-acetyltransferase.	0

>NZ_CP015250.1|WP_069356422.1|5087341_5089126_-|acyl-CoA-dehydrogenase
MEKTVGNAVKGGSFLVDEITIDQVFTPEDFSSEHKMIAKTTEDFIVNEVLPELEYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGGIGLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFVVYAKIDGEHFSAFIVEKEYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRKAMKGELPLLQKAQKLQEELMMMMPEEVGDEPLALQKYLVTNAKKIGLMVAGLAAQKYGKALDKEQEILVNIADIVSNLYAMESAVLRTEKAIKTTGLEKNKQKVLYTEVFCQEAFNEIEADAKETLIAVENGDMLRMMLSSLRKLTRHTPLNVIPKKREIAVKILEDERYTV
>NZ_CP015250.1|WP_069356421.1|5086532_5087255_-|MBL-fold-metallo-hydrolase
MRMIHEKALYQLSFLPRAFPVNCYFVEEDDGLTLIDAALPYSAKGILQAAEKIGKPITKIVLTHAHDDHIGALDALKEVLPHVPVHISKRDAKLLEGDTTLQKDEPNIPIKGGVPKKVKTVPDVLLEDGDRVGSLLAIMTPGHTPGSMSFLDVRNKALIVGDAFQTRGGMAVSGQMKFWFPFPAMATWSKEISLQSAQKLSEYEPSLLAAGHGKMIKNPGAVIELSIKEAKRNIESKKEG
>NZ_CP015250.1|WP_069356420.1|5085986_5086529_-|TetR/AcrR-family-transcriptional-regulator
MSPRIGLTLQKIVETAAEIADTNGIQEVTLASLAQRLGIRSPSLYNHVKGLQDVRKNLGIYGIKQLHNKLEEAAEDKRMDEVIHALGEAYVAFVRKHPGLYEATFLRDEEVRKAGDEIVKLCLRVLQQYGLEGENALHATRGFRSICHGFASIEQQGGFGLPLDLDISLHVLLETFIKGL
>NZ_CP015250.1|WP_069354784.1|5085652_5085922_-|transposase
MKKQYDEMFKRQCVELVIKEGRSISSIQREFDLGNGTLNVWIKKYSTQISSYESNELEELRSLRREIQALKKENEFLKKAATFFASNQN
>NZ_CP015250.1|WP_157452921.1|5084798_5085698_-|IS3-family-transposase
MSKKGGNLLCQQPKLTRFQFIRQYNQIFGVRWLCHRLQVSVSGFYDYIHRKPTENQKKRKKTAAYIVMQFKCLKGRMGYRKLYRYLVNKGVKVTLSQVRQALCKSGLQSKVVTYYKKRKQEHRTFPNVLKRSFKPGKKDIPTVVCDITEFRLMNGMKVYFCAALDISTRRVLGYSLDTCQDAQLVKDTIQQVKNTYGKRENILFHSDQGSQFSSYQVTDFCKQQKIQQSMSRKGNCWDNAVIESFFSIFKRECLHGEKLISLSQVNQLVAEFIYMYYHSVRPHSTLNGMTPYQYSKSIA
>NZ_CP015250.1|WP_069356419.1|5083572_5084286_-|CPBP-family-intramembrane-metalloprotease
MRKTVLDAYNAEREVDNITYKNLVVTIASILGFSLLGGLFLALALGIFGEEVLRANLEGYYLLLFDAAVVTIVLFAYKPVLHFIKNIWDVSVLKNGKTYLYLLIGFIIIALTQYVMLELFSFESAEQQRDQLGSLGLQNSLQSIIYVLSVAIITPIKEEILYRGILYRFFEKKYSFLVGIIISSFIFGILHGGFPVTAMIMGIVFAMLYKKTQSILPSIILHIVWNLLVSISMIVSL
>NZ_CP015250.1|WP_001180555.1|5083243_5083429_-|hypothetical-protein
MQNLTELEVENLRHLIGGHATIINKLEQYAQTCTDPQLKQMLQKDAQDARNTKQQLMTFLG
>NZ_CP015250.1|WP_001002981.1|5082981_5083230_-|spore-coat-protein
MNEKDMVNDYLAGLNASLTSYANYIAQSDNEQLHQTLIQIRNQDEARQRNMYEYAKQKSYYKPAAPANPMIVQQLKSQLSAE
>NZ_CP015250.1|WP_106823632.1|5081785_5082985_-|L-lactate-dehydrogenase
MTGKRRRANLFARFLFVYVNKYIINIFPVVTNMTKMEYNNSQKGQKLCSIFHKVSMVSIVRTSIIRIVKNKRNRLYDQLGEIAMKRHTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYQVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGGKPILQILEEQKERFGEIDLDEIVEKTAKAGWEIYKRKGTTYYGIGNSLAYIASSIFNDDHRVIAVSAILDGEYGEYDICTGVPAIITRDGIREVVELNLTEDEESRFAKSNDILRDYMKTIGY
>NZ_CP015250.1|WP_000666168.1|5080749_5081763_-|PTS-sugar-transporter-subunit-IIC
MKEYIMSRVFKASAGIAQGIFVSLGIGLLIENIGRIVDIPLLITIGVVAKSLMAPAIGAGIAFMLGANGLVIFSAMVAGAIGAGSISITEAGLIIKTGEPIGALLTATLAVYIGKRLSGKTALDMMLVPFAAILGSGLVGIWLSHNITPVLNAVGAFIKDSSAGSPFIASIVIAVVWGLLLISPASSAALAIALSLDGVAGGAALAGCVAQFIGFSVISAKENNLGGILAQALCTPKVQLPNITKNPMILVPTVVASAIVGPVSALIFQLEAGKEIAGLGLSSLIAPINLISSEGWEVLPAMVITYIVIPVAVSYILYIALKKAGRIHSGDMTVPQS
>NZ_CP015250.1|WP_001206331.1|5089467_5090640_-|acetyl-CoA-C-acetyltransferase
MREAVIVAGARTPIGKAKRGSLKTVRPDDLGALVVKETLKRANYEGPIDDLIFGCAMPEAEQGLNMARNIGGLAGLSYDVPAITINRYCSSGLQSIAYGAERIMLGHSEAVLSGGAESMSLVPMMGHVVRPNSRLVEAAPEYYMGMGHTAEQVAVKYGISREEQDAFAVRSHQRAAKALAAGNFADETVSVDVTLRSVGSNNKLQEETIIFAQDEGVRAETTLDILGKLRPAFNVRGSVTAGNSSQMSDGAASVLLMDREKAVSDGMKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFELNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFELL
>NZ_CP015250.1|WP_069356423.1|5090661_5093043_-|3-hydroxyacyl-CoA-dehydrogenase/enoyl-CoA-hydratase-family-protein
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLELLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKETDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMIKRGYSIGEVDSVTGPLIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPAFMHDMLDKKWFGSKTGQGFFLKQGKEILELNPETMEYEARKKLKAASVELSKQEKGLANKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEENGVVVPTWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGASLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIELVVKNFQDAMTKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMPNGVEFDLQKVANKVFESVAMAKVSTSAQEAVSNNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLVLGAEAMHLSGYISEHDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN
>NZ_CP015250.1|WP_001096344.1|5093280_5093427_+|YuzL-family-protein
MAKLKKNPSKAGISAASVTGNAGPHNHGVEKGRQGNNQQYKKHNMGEK
>NZ_CP015250.1|WP_023523353.1|5093524_5094364_+|D-alanyl-D-alanine-carboxypeptidase
MKRTIVMIVMIATLFTGMIFFSYAQRQQAVRADQPNITGQYGVTIDANTGEILYGKREDERSYPASIAKMMTTLLLLENVKEDEEITVTENAIKTESQSKKIKLRAGEKLKRDEALKLMLIISADPIAESIAEHIAGSKNEFVKMMNARAKELGTKHATFKNASGADAIGNKVSPYDIAIITKEALKYPVVLEYMNSTRTTLHTSERSPNIANYGREELYDDPYAIGSKSGLSALGKYTVVTVDEKDGKRVINVVLSSTRAQLYPDTKKMAHYAFQQLK
>NZ_CP015250.1|WP_000436780.1|5094386_5095304_-|proline-dehydrogenase
MEQLMRNSFLFLSKNKALTKLAKKYGLRFGAGRFVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGREGLDSQLSLKMTSMGLDISDEIVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSEYDNIGTVIQAYLYRTEKDIEDLNAYNPNLRLVKGAYKEPEEVAFPDKKDVDDNYKKIIKMHLLNGNYTAIASHDEAIIEYTKKLAEEHNIPRDQFEFQMLYGIRNERQLELVKEGYKMRVYVPYGNDWYGYFMRRLAERPANVAFVLKGMVKK
>NZ_CP015250.1|WP_001290600.1|5095615_5095861_-|YusU-family-protein
MSEKFNEQFDGLLEKYTELLLGESSEERKEQVQKWALYSYIAKTMPALVKHWNETYPDAKEEMVQLITDIKRLNEEKRNEQ
>NZ_CP015250.1|WP_069356424.1|5095909_5096212_-|MTH1187-family-thiamine-binding-protein
MAIVDVSIIPVGTGNPSVSEYVAEVQKVLEKNADRVKYQLTPMNTIIEGDLPVILEVIQQMHEVPYKKGAQRVATTIRIDDRRDKVSTMEKKLNSVRSKL
>NZ_CP015250.1|WP_069356425.1|5096289_5098290_-|methyl-accepting-chemotaxis-protein
MLRSLRLKIAVVFSVLISMMFVILGTAVYQLQKEKEVRSLDEYSQNAMDLVTEQLTTFIQRTDEDMGYYANSEMIRNMLQGGVTPEEEAFLTKEFAEYKKNHPGILDLYIGTKDKKTLSANLAEGGQVPEGYDPTTRPWYKDSEADVKKVHWGQPSYEIATGKLSVGVSKAITAQDGSVLGVVAMDVSLGTIQKLLHNIQYNNDGEMFIINDKNMALVYPEKIGKDVSKEPLIKSLNKEVTKYAVTTIKGEDVVVYSQSFDTMKWTIGIFYPKETIDGLLNSTRNTVIIMACISLLVGIVASYLFSRRLARPLQLLKNHVQKVAEGDLTLRMKVTSKDEVGELTKHFNDMVEQMNEMVSKIKNSVSTVQQSTNSLHYLTNETVAASREVSGAMDDVSGGASTLANSVDEVSAQLENMAESVEQMNSSVDEIKGVAGKAEEASKQGLNTMRNLIRTRGQSSSIVVHTEEASDKLEQRVGSIQNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATGEITTMIGDVQVEVKRVVEVVSKLKDIADVQNKVTTEAEMEFRTIMSVVNTISTSVEKIVEEVHNIGYEQGEITAVMHTIAGTSQESAAVSEEVHAATESQVNHLEKVAHTMESLTEHMRDLERLVEQFKVEE
>NZ_CP015250.1|WP_069356426.1|5098476_5099235_+|TrmB-family-transcriptional-regulator
MLQKFGFSQYESQAYEVVVSSNEPLDATTIVKHSGVPKAKIYEVLARLIDKGMVMDSVSEKKKLYTALPLKLAIEKLTTEFQSNIKELETNISKKSFTDDRVWSLKMQSSIRVQSKELIESAKESIRISAWNDTLLEYLPLLEQKAKQGVQIESLIVGEVETDLENMHFLIPAEEPNALERYLLLIVDDREILFAGVEQESWQAMKTMSQPFVKFFTEFFYHDVALAKITQKHHDLFMKDEEIKSLLMKLRY
>NZ_CP015250.1|WP_069356427.1|5099262_5099445_-|hypothetical-protein
MYSNFSIIGLLISMLPLFLIILALRWIRFIYQNSEKQVEQNEKIIELLMEIKEQNKKESK

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Crispr_ID: NZ_CP015250_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015250_9

5390515-5390648

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP015250_9

>merge|NZ_CP015250|9|5390515-5390648|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGGTTCTTCTTTTTTGTCACTAGTTGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTGTCTTCTGTTTTATTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP015250|9|7|5390515-5390648|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGG	TTCTTCTTTTTTGTCACTAGTTGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTGTCTTCTGTTTTATTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015250.1\|WP_069356553.1\|5399656_5401159_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP015250.1\|WP_000672651.1\|5394367_5395387_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP015250.1\|WP_069356552.1\|5397695_5397932_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP015250.1\|WP_069356547.1\|5385412_5386156_-\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP015250.1\|WP_069356554.1\|5401155_5403018_-\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
NZ_CP015250.1\|WP_025709680.1\|5383841_5384609_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP015250.1\|WP_069356549.1\|5391535_5392240_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP015250.1\|WP_069356548.1\|5386416_5387094_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP015250.1\|WP_001207149.1\|5384721_5385423_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP015250.1\|WP_000544012.1\|5389465_5389738_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP015250.1\|WP_084746309.1\|5398134_5399655_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP015250.1\|WP_069356550.1\|5392239_5393082_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP015250.1\|WP_003272396.1\|5396939_5397650_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP015250.1\|WP_000931959.1\|5387439_5387874_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP015250.1\|WP_000411275.1\|5395595_5396900_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP015250.1\|WP_000457978.1\|5388303_5389305_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP015250.1\|WP_069356546.1\|5382720_5383602_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP015250.1\|WP_000008903.1\|5390046_5390181_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015250.1\|WP_069356545.1\|5380845_5382660_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP015250.1\|WP_069356551.1\|5393259_5394267_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054

Protein	Function_ID	Function_description	E-value
NZ_CP015250.1\|WP_069356553.1\|5399656_5401159_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	4.11976e-178
NZ_CP015250.1\|WP_069356547.1\|5385412_5386156_-\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	2.62301e-83
NZ_CP015250.1\|WP_069356552.1\|5397695_5397932_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	6.73739e-23
NZ_CP015250.1\|WP_069356550.1\|5392239_5393082_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.59516e-90
NZ_CP015250.1\|WP_000672651.1\|5394367_5395387_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	5.30147e-135
NZ_CP015250.1\|WP_025709680.1\|5383841_5384609_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.31022e-105
NZ_CP015250.1\|WP_069356549.1\|5391535_5392240_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.584e-05
NZ_CP015250.1\|WP_069356548.1\|5386416_5387094_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.61933e-82
NZ_CP015250.1\|WP_001207149.1\|5384721_5385423_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.4197e-83
NZ_CP015250.1\|WP_000544012.1\|5389465_5389738_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP015250.1\|WP_084746309.1\|5398134_5399655_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	1.1151e-150
NZ_CP015250.1\|WP_069356551.1\|5393259_5394267_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.51089e-32
NZ_CP015250.1\|WP_003272396.1\|5396939_5397650_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	1.11897e-33
NZ_CP015250.1\|WP_000931959.1\|5387439_5387874_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP015250.1\|WP_000411275.1\|5395595_5396900_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP015250.1\|WP_000457978.1\|5388303_5389305_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP015250.1\|WP_069356546.1\|5382720_5383602_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP015250.1\|WP_069356545.1\|5380845_5382660_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP015250.1\|WP_069356554.1\|5401155_5403018_-\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0

>NZ_CP015250.1|WP_000008903.1|5390046_5390181_-|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEELEREE
>NZ_CP015250.1|WP_000544012.1|5389465_5389738_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP015250.1|WP_000457978.1|5388303_5389305_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP015250.1|WP_000931959.1|5387439_5387874_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP015250.1|WP_069356548.1|5386416_5387094_-|CpsD/CapB-family-tyrosine-protein-kinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHVRSIIVTSADPGDGKTTTIANLAVVFGQQGKKVLLIGADLRKPTIQNLFVIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKILGVVLNDKREGKEQYGYY
>NZ_CP015250.1|WP_069356547.1|5385412_5386156_-|capsular-biosynthesis-protein
MEETISLKELFHTLKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGAMFQAGEIQTNIQLTNTYKVIIKSPVILEQVNEKLNLNMTSQALTGKINVANEKDSQVISVTAEDKDPKLARDIANATADVFKGEVAKIMNVDNVTVLSKAEVAENQSPIKPAPMLNVAIAFSVGLIVSVGLAFLLEYLDNTVKKEEDVENLLGLPVLGIVARMDEETMNVKSHAPSSRKVRGQTIGS
>NZ_CP015250.1|WP_001207149.1|5384721_5385423_-|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAIDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTHSERLEKCVQTTSVDNLHFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASILVVRSESTEKETAVKAKGLLESAKGKLLGVVLNDREREEGLYYYYGAN
>NZ_CP015250.1|WP_025709680.1|5383841_5384609_-|tyrosine-protein-phosphatase
MIDLHCHILPGIDDGAQTVTDSLAMAQQAVAEGIHTIVATPHHQNGKYVNERTPIIHHVKQLNDELQQHNIPLTILPGQEVRLYGDLLEDYEADKIVTLNETNKYIFIEFPSNHVPRYAEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNLVNKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMVASDAHNTTSRGFHLAESYELIEKEFGMNVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP015250.1|WP_069356546.1|5382720_5383602_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPIEQCDRRYQVRQFVEKPAEGTAPSNLAIMGRYVLTPEIFMFLENQQTGAGGEIQLTDAIQRLNEVQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQNEDLNVELMKYMKELVKKEEVHS
>NZ_CP015250.1|WP_069356545.1|5380845_5382660_-|polysaccharide-biosynthesis-protein
MSYRRRLSLLILLDSFIVLTAVYLSYWFIHPNVLNKIPMTVIISSITLLCSHHVFAAIYKLYNKAWEYASIGELKQIFKAITLSILVTAIVQQIINHDIYVRILAIAWMLHLLLIGGSRFVWRMFRDTYITKATNDKKRTLIIGAGSAGTMVVRQLQHNKEADLYPIAFVDDDRNKQKLEIYNVPVVGTTNHIQEIVEDNDIEHIIIAIPSLNRGQINEIFEKCRKTKAKTQIVPMLEDLLDGKLSVNEFRDVQVEDLLGREPIKLDDAGIGEKITGKTILVTGAGGSIGSEICRQVMKYKPAKIVLLGHGENSIYNIEMEMRVTYKDTVEITTEIADIQDRHKIFEIMKKHQPYIVYHAAAHKHVPLMERNPEEAVKNNIFGTKNVAEAADTFKVNTFVMVSTDKAVNPTNVMGATKRFAEMIVQHMASVSTGTRFVAVRFGNVLGSRGSVIPLFKKQIQKGGPVTVTHPDMIRYFMTIPEASRLVIQAGTLARGGELFVLDMGAPVKIVDLAKNLITLSGFSIEEIGIEFTGLRPGEKMYEELLNEGEIHPEQIFPKIHIGKAVLIDQGILRQFMNDFEGISKEEIRERLLDIANNKVNIKN
>NZ_CP015250.1|WP_069356549.1|5391535_5392240_-|ABC-transporter-permease
MTFSMRRFSAIFRKEVQDFKTNSQVLLMAFLPIILSFLFSRFGVGKEMLGTTTIMAFLFVAGFVQSMVIAEEKEKHTLRVLMLSPASSVEVLLGKSLLTSGLTMVICIANLFILDQLNINLPLVGLIFLCGTILFIVLGTMIGLLASSVPQTSLIGMPILMTMYLAVQFEPMVENKVIKTLIEYLPTSHIVKAIKSLVDGAGFSSISGHVLNVGVWLIIALIACLIVYKKKQMD
>NZ_CP015250.1|WP_069356550.1|5392239_5393082_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFSGKTALRNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLTQVNLLDDKKTPVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNEEGTTIFLTTHNMDEAETLCNRIAFLCGGEIVALDTPENLRLQYAKNQIEVVLKDKQKEVVQKDELGAKRISEWMKKGELLSIHSHEPTLGDIFIEVTGRGL
>NZ_CP015250.1|WP_069356551.1|5393259_5394267_-|ATP-binding-cassette-domain-containing-protein
MALLELKQLGKANQLPAVELEVEKGQCIVLQCNNHTAKVLHRIIIGEEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLLGLYESKISIEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDIESTVIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKVEIEQEEAEKVDEEKVVQIIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLSELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP015250.1|WP_000672651.1|5394367_5395387_-|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVESLPMEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGGKKNNADVTDTVKDQVYKSKDELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVEIKTMNDYEGKLMVKK
>NZ_CP015250.1|WP_000411275.1|5395595_5396900_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP015250.1|WP_003272396.1|5396939_5397650_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVLFLVGYREMKPISDEQKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKDKANIQKWEVEQSPDGYKATSYKKFASHEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQKVNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP015250.1|WP_069356552.1|5397695_5397932_-|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMNSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP015250.1|WP_084746309.1|5398134_5399655_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCIAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKNRASNEAAMKYVISGGIGTAITLFGMSYLYGITGSTNIVDMQKVLTGELASGIQLLLALAVLLLLVGLSFKIATVPFHMWAPDVYEGATTPVTAFLGTISKIAGFLLIIRLFLMVFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTLDSMWFYMLAYMLMNIGAFAIIHGLILQNDKENITIFTGLYKKSPFAAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP015250.1|WP_069356553.1|5399656_5401159_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAIVLACTYASGKSLSLFDEKVKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLAMLAAIAAFSIKRNLKAFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIVELKEILRSVSAEGELIIPSSLQLGVFISIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDIATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLAALNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSEITALGGLAKSVPVLSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK
>NZ_CP015250.1|WP_069356554.1|5401155_5403018_-|NADH-quinone-oxidoreductase-subunit-L
MIDYAWLIPLFPLVSFLLLIIFGKKIREGSSVLSIFFVFLSFILAVLVLIERFSEASVKHKWVWLRAGDVDISFGFEVTALGALMLFIVTLVSLLVHVYSKGYMKGDERLPTFYAYLGLFTFAMLGLVISTNLLQLYIFWELVGLGSFLLIGFYFFKEEVKAAAKKAFIMTRIGDVGLFIGMILIFWYAGSFEYDAIFRAIYTGDLPPYMITITAILIFIGAMGKSGQFPLHTWLPDAMEGPTPVSALIHAATMVAAGVYLVATMFPLFSASTVAMQTVAIVGAFTAIFAASIGLVQTDIKRVLAYSTVSQLGYMMLALGSAGYVAGVFHLTTHAFFKALLFLAAGSVIHAVHTQNINKMGGLQKKMKVTGTLFLIGTLAISGVPLLSGFFSKDEILAATWMNGNYVLFTLAVIAAFLTAFYMFRLYFLVFTGETKTKEDVHESPRVMTYPMIVLGVLAVVAGYINTPWFGTFLGDWLTKDVGFKVEEAHGPVWIMIVATLVSFAGIALAYFIYGKKSISRDWAGGTETSLYNLLKEKYYVDELYNMTVIPITKGIAHVLRLFEVYVVEGIAVLIGSVVKGTSNLGSKLQNGNVQVYGTVTAVSLAVLVIILLYTGGDLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015250_1	1.2\|1651769\|30\|NZ_CP015250\|CRT	1651769-1651798	30	NC_017074	Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC5, complete sequence	33031-33060	7	0.767
NZ_CP015250_1	1.2\|1651769\|30\|NZ_CP015250\|CRT	1651769-1651798	30	NC_010408	Clavibacter michiganensis subsp. sepedonicus plasmid pCSL1, complete sequence	50963-50992	7	0.767
NZ_CP015250_1	1.2\|1651769\|30\|NZ_CP015250\|CRT	1651769-1651798	30	NZ_CP042507	Leclercia adecarboxylata strain E1 plasmid pE1_002, complete sequence	97957-97986	7	0.767
NZ_CP015250_1	1.2\|1651769\|30\|NZ_CP015250\|CRT	1651769-1651798	30	NZ_CP026170	Leclercia sp. LSNIH1 plasmid pLEC-000f, complete sequence	65102-65131	7	0.767
NZ_CP015250_1	1.2\|1651769\|30\|NZ_CP015250\|CRT	1651769-1651798	30	NZ_CP052873	Enterobacter cloacae strain 3849 plasmid p3846III, complete sequence	124708-124737	7	0.767
NZ_CP015250_1	1.2\|1651769\|30\|NZ_CP015250\|CRT	1651769-1651798	30	NZ_CP026390	Leclercia sp. LSNIH3 plasmid pLEC-5e18, complete sequence	79130-79159	7	0.767
NZ_CP015250_6	6.2\|4824768\|30\|NZ_CP015250\|CRISPRCasFinder	4824768-4824797	30	NZ_CP022424	Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence	120413-120442	8	0.733
NZ_CP015250_9	9.1\|5390538\|31\|NZ_CP015250\|CRISPRCasFinder	5390538-5390568	31	JX238501	Bacillus phage phiAGATE, complete genome	124559-124589	8	0.742
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_CP014851	Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence	100650-100683	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	8	0.765
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47181-47214	11	0.676
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47565-47598	11	0.676
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47949-47982	11	0.676
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48333-48366	11	0.676
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48717-48750	11	0.676
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49101-49134	11	0.676
NZ_CP015250_9	9.2\|5390592\|34\|NZ_CP015250\|CRISPRCasFinder	5390592-5390625	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49485-49518	11	0.676

1. spacer 1.2|1651769|30|NZ_CP015250|CRT matches to NC_017074 (Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC5, complete sequence) position: , mismatch: 7, identity: 0.767

agtagcgcctgctggcccttgaacgccttg	CRISPR spacer
ttgaacgcctgctggcccttgaacgcttaa	Protospacer
   *.*********************.* .

2. spacer 1.2|1651769|30|NZ_CP015250|CRT matches to NC_010408 (Clavibacter michiganensis subsp. sepedonicus plasmid pCSL1, complete sequence) position: , mismatch: 7, identity: 0.767

agtagcgcctgctggcccttgaacgccttg	CRISPR spacer
gcgagctgctgctggcccttgaacgcccag	Protospacer
.  ***  *******************. *

3. spacer 1.2|1651769|30|NZ_CP015250|CRT matches to NZ_CP042507 (Leclercia adecarboxylata strain E1 plasmid pE1_002, complete sequence) position: , mismatch: 7, identity: 0.767

agtagcgcctgctggcccttgaacgccttg	CRISPR spacer
agccctacctgctcgcccctgaacgccttg	Protospacer
**.  ..****** ****.***********

4. spacer 1.2|1651769|30|NZ_CP015250|CRT matches to NZ_CP026170 (Leclercia sp. LSNIH1 plasmid pLEC-000f, complete sequence) position: , mismatch: 7, identity: 0.767

agtagcgcctgctggcccttgaacgccttg	CRISPR spacer
agccctacctgctcgcccctgaacgccttg	Protospacer
**.  ..****** ****.***********

5. spacer 1.2|1651769|30|NZ_CP015250|CRT matches to NZ_CP052873 (Enterobacter cloacae strain 3849 plasmid p3846III, complete sequence) position: , mismatch: 7, identity: 0.767

agtagcgcctgctggcccttgaacgccttg	CRISPR spacer
agccctacctgctcgcccctgaacgccttg	Protospacer
**.  ..****** ****.***********

6. spacer 1.2|1651769|30|NZ_CP015250|CRT matches to NZ_CP026390 (Leclercia sp. LSNIH3 plasmid pLEC-5e18, complete sequence) position: , mismatch: 7, identity: 0.767

agtagcgcctgctggcccttgaacgccttg	CRISPR spacer
agccctacctgctcgcccctgaacgccttg	Protospacer
**.  ..****** ****.***********

7. spacer 6.2|4824768|30|NZ_CP015250|CRISPRCasFinder matches to NZ_CP022424 (Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence) position: , mismatch: 8, identity: 0.733

ggacctgttgggccaatccccccttgagca	CRISPR spacer
cggtgggttggcccaatccccgcttgagcg	Protospacer
 *..  ***** ********* *******.

8. spacer 9.1|5390538|31|NZ_CP015250|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

ttcttcttttttgtcactagttgaaccgctt	CRISPR spacer
ctaaccttttttgccactagttaaaccgccc	Protospacer
.*  .********.********.******..

9. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_CP014851 (Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tttatcttcttttttattttctggtttattttcc	Protospacer
.**.****** ****************  * ..*

10. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

11. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

12. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

13. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

14. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

15. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

16. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

17. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

18. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

19. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

20. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

21. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

22. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

23. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

24. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

25. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

26. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

27. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

28. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

29. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

30. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

31. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

32. spacer 9.2|5390592|34|NZ_CP015250|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

235078 : 301107

Bacillus_phage(17.65%)

tRNA,transposase,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_064531738.1\|235078_235651_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_000583418.1\|235744_236104_+	holo-ACP synthase	NA	NA	NA	NA
WP_002094231.1\|236260_237211_+	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
WP_069354767.1\|237328_238498_+	alanine racemase	NA	NA	NA	NA
WP_000004570.1\|238806_239094_+	antitoxin EndoAI	NA	NA	NA	NA
WP_000635965.1\|239098_239449_+	type II toxin-antitoxin system endoribonuclease NdoA	A0A2P0ZKX3	Lactobacillus_phage	1.7e-13	37.7
WP_000426207.1\|239517_241686_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_001143640.1\|241743_241860_-	cortex morphogenetic protein CmpA	NA	NA	NA	NA
WP_069354768.1\|242055_242514_+	SprT family protein	NA	NA	NA	NA
WP_069354769.1\|249010_249484_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_069354770.1\|249464_250157_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_000367207.1\|250171_250615_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_065229655.1\|250614_251631_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	5.4e-68	43.1
WP_069354771.1\|252112_254101_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	5.1e-54	30.3
WP_069354772.1\|254233_254863_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_001246204.1\|254892_255084_-	YdiK family protein	NA	NA	NA	NA
WP_053565405.1\|255080_255830_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000917311.1\|256221_256506_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8
WP_001029992.1\|256544_258179_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.3e-156	57.8
WP_069354773.1\|258740_259970_+	WXG100 family type VII secretion target	A0A2H4J389	uncultured_Caudovirales_phage	2.6e-64	58.9
WP_000481695.1\|259990_260449_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_000743908.1\|261115_262654_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	8.8e-22	31.7
WP_000833094.1\|263039_264365_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	7.1e-44	29.5
WP_000929891.1\|264510_265212_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.3e-40	36.9
WP_016513331.1\|265195_266701_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	5.4e-32	30.8
WP_000821101.1\|272012_272972_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_069354774.1\|273171_273903_+	DsbA family oxidoreductase	NA	NA	NA	NA
WP_069354776.1\|280380_281133_-	AAA family ATPase	A0A059NT77	Lactococcus_phage	7.8e-56	46.9
WP_069354777.1\|281122_282418_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-09	27.1
WP_069354779.1\|282989_284363_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_069356602.1\|284480_285440_+	proline dehydrogenase	NA	NA	NA	NA
WP_069354780.1\|291464_292541_-	glycosyl transferase	NA	NA	NA	NA
WP_000551407.1\|292774_293647_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000405127.1\|293674_294397_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_053565457.1\|294612_295407_-	RNA methyltransferase	A0A288WG17	Bacillus_phage	8.8e-66	51.2
WP_069354781.1\|295700_296606_+	NAD-dependent epimerase/dehydratase family protein	L7RCI0	Acanthamoeba_polyphaga_moumouvirus	4.5e-26	31.0
WP_069354782.1\|296692_297988_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.5e-11	27.5
WP_069354783.1\|297977_298730_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	3.5e-56	46.5
WP_053565455.1\|298874_299651_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_069354784.1\|299983_300253_+\|transposase	transposase	NA	NA	NA	NA
WP_157452918.1\|300207_301107_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	7.2e-24	37.3

DBSCAN-SWA_2

349999 : 485929

151

Bacillus_phage(77.42%)

holin,tRNA,terminase,transposase,plate,coat,capsid,protease,tail,head,portal,integrase

attL 347355:347373|attR 471242:471260

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
347355:347373	attL	NA	NA	NA	NA
WP_000086999.1\|349999_350290_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000051441.1\|350305_351763_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_001047685.1\|351777_353205_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_000977679.1\|353709_354615_+	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	4.1e-27	30.8
WP_064532115.1\|354755_355499_+	HAD family hydrolase	NA	NA	NA	NA
WP_047792105.1\|355578_357018_+	4-aminobutyrate--2-oxoglutarate transaminase	NA	NA	NA	NA
WP_053565389.1\|357133_358501_+	PAS domain-containing protein	NA	NA	NA	NA
WP_069354794.1\|358493_359945_+	NADP-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000263262.1\|359992_360316_+	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_064532119.1\|360448_360940_+	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_000007372.1\|360985_362215_-	aminopeptidase	NA	NA	NA	NA
WP_064532121.1\|362331_363414_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_069354795.1\|364101_365169_-\|integrase	site-specific integrase	H0UST3	Bacillus_phage	5.0e-157	76.9
WP_069354796.1\|365957_367220_+	transcriptional regulator	W8CYT9	Bacillus_phage	6.5e-188	79.9
WP_030022621.1\|367578_367926_-	helix-turn-helix transcriptional regulator	I7J6V3	Bacillus_phage	7.0e-52	92.0
WP_065484921.1\|368072_368309_+	helix-turn-helix transcriptional regulator	W8CYU0	Bacillus_phage	1.3e-33	92.2
WP_023523419.1\|368341_368530_+	helix-turn-helix transcriptional regulator	W8CYN7	Bacillus_phage	5.7e-24	90.3
WP_069354797.1\|369036_369339_+	hypothetical protein	A0A0S2GLB6	Bacillus_phage	1.1e-24	60.8
WP_069354798.1\|369637_370456_+	replication protein	A0A1P8VVR3	Streptococcus_phage	6.8e-21	45.7
WP_069354799.1\|370406_371270_+	ATP-binding protein	A0A1B0T6C3	Bacillus_phage	5.6e-90	63.3
WP_069354800.1\|371283_371571_+	hypothetical protein	A0A1B1P7W1	Bacillus_phage	3.0e-16	47.4
WP_069354801.1\|371567_371834_+	hypothetical protein	A0A0S2GLK4	Bacillus_phage	3.1e-23	61.4
WP_069354802.1\|371872_372040_+	DUF3954 domain-containing protein	A0A0S2GLF5	Bacillus_phage	2.8e-14	64.8
WP_069354803.1\|372073_372883_+	phage antirepressor KilAC domain-containing protein	A0A2H4JAT4	uncultured_Caudovirales_phage	2.6e-73	50.8
WP_069354804.1\|373012_373216_-	hypothetical protein	A0A2H4J3A3	uncultured_Caudovirales_phage	6.4e-13	67.3
WP_127064183.1\|373431_373545_+	DUF3983 domain-containing protein	A0A1B0T6D3	Bacillus_phage	9.9e-08	86.5
WP_069354805.1\|373847_374333_+	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	5.9e-81	93.2
WP_065485748.1\|374329_374872_+\|integrase	site-specific integrase	A0A1B0T6D2	Bacillus_phage	3.5e-90	93.9
WP_069354806.1\|375078_375303_+	hypothetical protein	W8CYG8	Bacillus_phage	5.2e-24	73.6
WP_069354807.1\|375584_376340_-	hypothetical protein	NA	NA	NA	NA
WP_069354808.1\|376893_377835_+	hypothetical protein	A0A2I7SCF1	Paenibacillus_phage	7.7e-69	57.6
WP_069354809.1\|377844_378216_+	hypothetical protein	NA	NA	NA	NA
WP_069354810.1\|378366_378681_+	hypothetical protein	A0A1B0T6C6	Bacillus_phage	5.6e-40	78.8
WP_069354811.1\|378677_379070_+	HNH endonuclease	A0A1B1P7N1	Bacillus_phage	6.2e-73	96.2
WP_069354812.1\|379152_379578_+\|terminase	P27 family phage terminase small subunit	A0A1B0T688	Bacillus_phage	1.2e-64	88.6
WP_069354813.1\|379574_381299_+\|terminase	terminase large subunit	A0A1B0T685	Bacillus_phage	2.2e-308	90.4
WP_069354814.1\|381314_382499_+\|portal	phage portal protein	A0A1B0T684	Bacillus_phage	3.1e-216	96.4
WP_069354815.1\|382488_383070_+\|head,protease	HK97 family phage prohead protease	A0A1B0T687	Bacillus_phage	7.3e-94	94.2
WP_069354816.1\|383071_384370_+\|capsid	phage major capsid protein	A0A1B0T682	Bacillus_phage	1.4e-182	97.6
WP_069354817.1\|384438_384756_+	collagen-like protein	NA	NA	NA	NA
WP_069354818.1\|384770_385031_+\|head,tail	phage gp6-like head-tail connector protein	A0A1C8E967	Bacillus_phage	1.4e-36	88.4
WP_069354819.1\|385008_385341_+	hypothetical protein	A0A1C8E986	Bacillus_phage	5.7e-51	93.5
WP_069354820.1\|385330_385660_+	hypothetical protein	A0A1B1P7P2	Bacillus_phage	2.2e-55	96.3
WP_069354821.1\|385659_386037_+	HK97 gp10 family phage protein	A0A1C8E995	Bacillus_phage	6.2e-62	96.0
WP_069354822.1\|386048_386705_+\|tail	phage tail protein	A0A1B1P7Q4	Bacillus_phage	1.8e-104	88.2
WP_069354823.1\|386716_387103_+	hypothetical protein	A0A1C8E984	Bacillus_phage	1.5e-63	96.1
WP_015406517.1\|387141_387330_+	hypothetical protein	A0A1C8E979	Bacillus_phage	4.1e-30	96.8
WP_069354824.1\|390871_391555_+\|tail	phage tail protein	A0A1B0T6A0	Bacillus_phage	1.4e-125	96.0
WP_069354825.1\|391551_393894_+	endopeptidase	A0A1B0T695	Bacillus_phage	0.0e+00	94.5
WP_069354826.1\|395137_395419_+	hypothetical protein	D2XR31	Bacillus_phage	1.3e-32	75.3
WP_069354827.1\|395421_395625_+	hypothetical protein	D2XR32	Bacillus_phage	1.7e-18	62.1
WP_069354828.1\|395684_396725_+	N-acetylmuramoyl-L-alanine amidase	A0A1B1P878	Bacillus_phage	1.2e-160	78.8
WP_069354829.1\|396706_396958_-	hypothetical protein	A0A1B0T6A3	Bacillus_phage	4.2e-22	92.3
WP_069354830.1\|398262_398493_-	helix-turn-helix domain-containing protein	S5MBY6	Brevibacillus_phage	4.1e-08	38.9
WP_139362471.1\|398735_398867_+	hypothetical protein	W8CYT8	Bacillus_phage	3.2e-18	90.7
WP_069354831.1\|398884_399205_+	hypothetical protein	A0A0S2GLK1	Bacillus_phage	3.4e-37	67.0
WP_069354832.1\|399216_400383_+	DNA translocase FtsK	A0A0S2GLG9	Bacillus_phage	6.4e-190	83.2
WP_069354833.1\|400372_400981_+	hypothetical protein	A0A0S2GLL8	Bacillus_phage	1.3e-98	87.1
WP_069354834.1\|400977_401859_-	cytosolic protein	I7ILW0	Bacillus_phage	1.3e-110	75.8
WP_065486040.1\|402227_402824_+	hypothetical protein	NA	NA	NA	NA
WP_016083714.1\|402870_404067_-	NupC family nucleoside transporter	NA	NA	NA	NA
WP_069354835.1\|404492_405872_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	4.2e-116	46.3
WP_069354836.1\|405930_407055_-\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	4.0e-213	98.7
WP_069354837.1\|407911_408475_-	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	5.1e-36	49.0
WP_069354838.1\|408609_408954_-	DUF4064 domain-containing protein	A0A0S2MVJ2	Bacillus_phage	2.6e-43	82.5
WP_069354839.1\|408973_409501_-	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	1.6e-87	95.4
WP_069354840.1\|409686_410040_-	helix-turn-helix transcriptional regulator	A0A1B1P888	Bacillus_phage	2.6e-22	46.4
WP_084746330.1\|410556_411684_+	hypothetical protein	H0UST6	Bacillus_phage	2.4e-109	52.1
WP_069356603.1\|411975_412158_+	hypothetical protein	NA	NA	NA	NA
WP_001020466.1\|412168_412516_-	helix-turn-helix transcriptional regulator	S5MUA5	Brevibacillus_phage	1.3e-10	39.4
WP_069354842.1\|412681_412954_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069354843.1\|412916_413642_+	Rha family transcriptional regulator	A0A1B1P7T7	Bacillus_phage	6.9e-110	80.2
WP_069354844.1\|413685_414036_+	helix-turn-helix domain-containing protein	A0A1B0T6C2	Bacillus_phage	2.4e-52	87.1
WP_157452919.1\|414032_414200_+	hypothetical protein	A0A0U3B230	Bacillus_phage	6.0e-17	79.6
WP_069354845.1\|414410_415280_+	chromosomal replication initiator DnaA	A0A0U3TZZ4	Bacillus_phage	1.9e-98	68.0
WP_042595748.1\|415294_416209_+	AAA family ATPase	A0A0U3U1U1	Bacillus_phage	2.4e-168	98.0
WP_069354846.1\|416221_416416_+	hypothetical protein	A0A1B1P7U7	Bacillus_phage	8.7e-28	92.2
WP_069354847.1\|416432_416711_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	2.5e-12	59.3
WP_069354848.1\|416703_417063_+	cell division protein SepF	A0A1B1P7A1	Bacillus_phage	3.2e-31	52.5
WP_000717826.1\|417082_417250_+	DUF3954 domain-containing protein	A0A1B0T6B8	Bacillus_phage	1.4e-13	62.3
WP_000109490.1\|417275_417527_+	hypothetical protein	A0A0K2CNP4	Brevibacillus_phage	4.9e-07	42.2
WP_069354849.1\|417546_418002_+	nucleoside triphosphate pyrophosphohydrolase family protein	A0A0U4IBD0	Bacillus_phage	1.9e-20	49.5
WP_069354850.1\|418041_418230_+	hypothetical protein	NA	NA	NA	NA
WP_069354851.1\|418267_418600_+	hypothetical protein	NA	NA	NA	NA
WP_069354852.1\|418811_419009_+	hypothetical protein	A0A1B1P864	Bacillus_phage	5.9e-24	81.5
WP_016136473.1\|419045_419243_+	hypothetical protein	I7IDJ9	Bacillus_phage	3.6e-29	96.9
WP_016090449.1\|419429_419612_+	hypothetical protein	A0A0S2MVH2	Bacillus_phage	4.3e-29	100.0
WP_000130745.1\|419641_419764_+	DUF3983 domain-containing protein	NA	NA	NA	NA
WP_001013578.1\|419784_419973_+	hypothetical protein	NA	NA	NA	NA
WP_069354853.1\|420210_421356_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.7e-41	28.5
WP_069354855.1\|421837_422320_+	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	1.2e-70	82.5
WP_069354856.1\|422319_422862_+\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	8.6e-89	91.1
WP_069354857.1\|423512_423731_+	cell division protein FtsK	A0A1B1P7C1	Bacillus_phage	5.1e-08	41.5
WP_069354858.1\|423771_424035_+	hypothetical protein	NA	NA	NA	NA
WP_069354859.1\|424040_424370_+	HNH endonuclease	A0A1B1P757	Bacillus_phage	4.6e-21	51.0
WP_069354860.1\|424372_424681_+	hypothetical protein	NA	NA	NA	NA
WP_069354861.1\|424990_425491_+	RNA polymerase subunit sigma-70	A0A1B1P762	Bacillus_phage	3.3e-10	35.6
WP_069354862.1\|425474_427142_+\|terminase	terminase large subunit	A0A1B1P766	Bacillus_phage	1.0e-180	57.8
WP_069354863.1\|427160_428399_+\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	1.8e-78	39.8
WP_069354864.1\|428340_429048_+\|protease	Clp protease ClpP	D2XR17	Bacillus_phage	1.4e-43	50.8
WP_069354865.1\|429064_430195_+\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	1.3e-99	51.0
WP_069354866.1\|430211_430535_+	hypothetical protein	A0A1B1P751	Bacillus_phage	7.8e-13	39.8
WP_069354867.1\|430524_430890_+\|head,tail	phage head-tail adapter protein	NA	NA	NA	NA
WP_069354868.1\|430867_431248_+	hypothetical protein	NA	NA	NA	NA
WP_069354869.1\|431237_431648_+	hypothetical protein	NA	NA	NA	NA
WP_069354870.1\|431649_432213_+\|tail	phage tail protein	Q8W5Z9	Listeria_phage	1.3e-39	44.5
WP_069354871.1\|432287_432656_+	hypothetical protein	A0A1S7FZ84	Listeria_phage	1.7e-08	33.7
WP_069354872.1\|432838_436621_+\|tail	phage tail tape measure protein	A0A1C8E982	Bacillus_phage	9.9e-75	58.6
WP_069354873.1\|436613_437300_+\|tail	phage tail protein	A0A2H4J851	uncultured_Caudovirales_phage	1.7e-81	63.7
WP_069354874.1\|439536_439803_+	transcriptional regulator	NA	NA	NA	NA
WP_069354853.1\|440002_441148_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.7e-41	28.5
WP_069354875.1\|441433_442993_+\|plate	BppU family phage baseplate upper protein	B5LPS6	Bacillus_virus	9.6e-125	51.1
WP_069354876.1\|443005_443509_+	hypothetical protein	A0A1B1P805	Bacillus_phage	1.1e-58	67.1
WP_069354853.1\|443827_444973_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.7e-41	28.5
WP_069354877.1\|445319_446279_+\|integrase	site-specific integrase	A0A0S2GLC8	Bacillus_phage	9.6e-176	95.3
WP_069354878.1\|446294_446720_+\|holin	phage holin family protein	A0A1B1P787	Bacillus_phage	3.7e-71	97.9
WP_069354879.1\|446719_447505_+	N-acetylmuramoyl-L-alanine amidase	S5M842	Bacillus_phage	1.9e-76	58.8
WP_000566708.1\|448069_449059_+\|tRNA	tRNA-dihydrouridine synthase	NA	NA	NA	NA
WP_064532123.1\|449654_450683_+	hypothetical protein	NA	NA	NA	NA
WP_064532125.1\|450737_451292_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_064532127.1\|451641_452160_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.6e-20	36.5
WP_064532129.1\|452255_452963_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_064532131.1\|453163_453859_-	hypothetical protein	NA	NA	NA	NA
WP_064532133.1\|453873_454983_-	dipeptide epimerase	Q6A202	Oenococcus_phage	1.5e-18	25.3
WP_064532135.1\|455076_456348_+	hypothetical protein	NA	NA	NA	NA
WP_064532137.1\|456336_457758_-	Na+/H+ antiporter NhaC	NA	NA	NA	NA
WP_069354880.1\|458054_459206_+	amidohydrolase	NA	NA	NA	NA
WP_001005627.1\|459364_459970_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_069354881.1\|460006_461533_-	alkyl hydroperoxide reductase subunit F	A0A1W6JNB4	Lactococcus_phage	4.1e-19	30.8
WP_000924420.1\|461547_462111_-	peroxiredoxin	NA	NA	NA	NA
WP_053565378.1\|462702_463932_+	S-methyl-5-thioribose kinase	NA	NA	NA	NA
WP_064532143.1\|463941_464988_+	S-methyl-5-thioribose-1-phosphate isomerase	NA	NA	NA	NA
WP_053565376.1\|465041_465683_+	L-fuculose-phosphate aldolase	NA	NA	NA	NA
WP_053565375.1\|466111_467119_-	iron ABC transporter permease	NA	NA	NA	NA
WP_053565374.1\|467115_468156_-	iron ABC transporter permease	NA	NA	NA	NA
WP_053565373.1\|468204_469122_-	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_064532145.1\|469455_470505_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_000235474.1\|470701_471070_-	hypothetical protein	NA	NA	NA	NA
WP_000276022.1\|471265_471496_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
471242:471260	attR	NA	NA	NA	NA
WP_053565371.1\|471731_472247_+	hypothetical protein	NA	NA	NA	NA
WP_053565370.1\|472267_472717_+\|coat	spore coat protein	NA	NA	NA	NA
WP_053565369.1\|472879_473548_+	hypothetical protein	NA	NA	NA	NA
WP_000434728.1\|473786_475052_+	hypothetical protein	NA	NA	NA	NA
WP_069354786.1\|476273_477386_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000424116.1\|478223_478604_+	hypothetical protein	NA	NA	NA	NA
WP_053565367.1\|478632_479265_-	cyclase family protein	NA	NA	NA	NA
WP_069354883.1\|479612_480722_+	hypothetical protein	NA	NA	NA	NA
WP_069354884.1\|480833_481616_+	nucleotidyltransferase domain-containing protein	Q8SCS5	Pseudomonas_phage	8.4e-45	43.5
WP_069354885.1\|481629_482931_-	aromatic acid/H+ symport family MFS transporter	NA	NA	NA	NA
WP_069354886.1\|483074_484601_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_069354786.1\|484816_485929_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

786436 : 862861

Bacillus_phage(78.43%)

holin,terminase,transposase,capsid,protease,tail,head,portal,integrase

attL 794997:795016|attR 840758:840777

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069354786.1\|786436_787549_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000665754.1\|789259_789601_+	hypothetical protein	NA	NA	NA	NA
WP_000964465.1\|789622_789952_+	hypothetical protein	NA	NA	NA	NA
WP_000873271.1\|789968_791123_-	MFS transporter	NA	NA	NA	NA
WP_000645827.1\|791348_792401_+	(R,R)-butanediol dehydrogenase	E3SJ82	Synechococcus_phage	3.9e-21	27.6
WP_000948241.1\|792519_792864_+	two pore domain potassium channel family protein	NA	NA	NA	NA
WP_000730997.1\|793117_793969_+	phospholipase C	NA	NA	NA	NA
WP_069354969.1\|794045_795020_+	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	4.5e-88	59.5
794997:795016	attL	NA	NA	NA	NA
WP_069354970.1\|795030_796131_-\|integrase	site-specific integrase	A0A0S2GLI2	Bacillus_phage	2.2e-200	97.0
WP_069354971.1\|796940_798161_+	hypothetical protein	A0A0U3TNF6	Bacillus_phage	2.3e-113	50.9
WP_069354972.1\|798563_798908_-	helix-turn-helix transcriptional regulator	H0UST7	Bacillus_phage	4.7e-16	41.5
WP_000819158.1\|799077_799284_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069354973.1\|799349_799538_+	helix-turn-helix transcriptional regulator	W8CYN7	Bacillus_phage	3.3e-24	91.9
WP_069354974.1\|799750_800545_+	antirepressor	A0A0S2GLP8	Bacillus_phage	2.0e-134	94.7
WP_069354975.1\|800707_801022_+	hypothetical protein	A0A0S2GLB6	Bacillus_phage	2.7e-50	96.2
WP_069354777.1\|801316_802612_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-09	27.1
WP_069354776.1\|802601_803354_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	7.8e-56	46.9
WP_060851838.1\|803544_804192_+	sigma-70 family RNA polymerase sigma factor	A0A0S2GLJ1	Bacillus_phage	3.5e-113	96.7
WP_069354976.1\|804435_805440_+	DNA replication protein DnaD	A0A0S2GLI6	Bacillus_phage	2.6e-184	96.7
WP_069354977.1\|805402_806215_+	DNA replication protein	A0A0S2GLK2	Bacillus_phage	7.4e-153	98.9
WP_000436951.1\|806256_806523_+	hypothetical protein	A0A0S2GLK4	Bacillus_phage	7.7e-43	100.0
WP_069354978.1\|806594_806759_+	DUF3954 domain-containing protein	A0A0S2GLF5	Bacillus_phage	7.1e-23	94.4
WP_069354979.1\|807147_807390_+	hypothetical protein	A0A0S2MV78	Bacillus_phage	3.8e-28	71.2
WP_069354980.1\|807433_807769_+	hypothetical protein	NA	NA	NA	NA
WP_069354981.1\|808091_808694_-	hypothetical protein	NA	NA	NA	NA
WP_069354983.1\|809093_809492_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_069354984.1\|810372_810654_+	hypothetical protein	A0A0S2GLD3	Bacillus_phage	9.7e-44	97.8
WP_069354985.1\|811017_811503_+	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	2.5e-71	80.7
WP_069354986.1\|811499_812042_+\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	3.8e-89	91.7
WP_069354987.1\|812244_812490_+	hypothetical protein	W8CYG8	Bacillus_phage	5.8e-37	96.3
WP_030022649.1\|814324_814537_+	hypothetical protein	A0A0S2GM40	Bacillus_phage	3.3e-28	94.3
WP_084746338.1\|814771_814981_+	hypothetical protein	NA	NA	NA	NA
WP_069354989.1\|814970_815345_+	HNH endonuclease	A0A2H4J3B4	uncultured_Caudovirales_phage	3.0e-56	82.3
WP_069354990.1\|815663_816167_+\|terminase	phage terminase small subunit P27 family	A0A0S2GLF2	Bacillus_phage	3.3e-87	98.2
WP_069354991.1\|816168_817863_+\|terminase	terminase large subunit	H0USW3	Bacillus_phage	0.0e+00	98.2
WP_069354992.1\|818051_819305_+\|portal	phage portal protein	A0A0S2GLJ4	Bacillus_phage	3.2e-240	98.8
WP_069354993.1\|819291_820002_+\|protease	Clp protease ClpP	H0USW5	Bacillus_phage	6.7e-126	97.9
WP_069354994.1\|820039_821212_+\|capsid	phage major capsid protein	H0USW6	Bacillus_phage	9.8e-207	96.1
WP_069354995.1\|821232_821520_+\|head,tail	phage gp6-like head-tail connector protein	H0USW7	Bacillus_phage	5.6e-39	86.2
WP_069354996.1\|821506_821830_+\|head	phage head closure protein	W8CYF9	Bacillus_phage	1.4e-54	96.3
WP_000763224.1\|821822_822260_+	HK97 gp10 family phage protein	A0A0S2GLH3	Bacillus_phage	1.8e-76	99.3
WP_069354997.1\|822256_822616_+	DUF3168 domain-containing protein	W8CYY6	Bacillus_phage	2.9e-61	98.3
WP_000896770.1\|822616_823225_+\|tail	tail protein	W8CYT6	Bacillus_phage	5.8e-102	100.0
WP_069354998.1\|823274_823592_+	hypothetical protein	A0A0S2GLH2	Bacillus_phage	2.1e-50	93.3
WP_069354786.1\|827407_828520_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069354999.1\|828888_829239_+	hypothetical protein	A0A288WG88	Bacillus_phage	1.9e-44	78.4
WP_084745960.1\|829253_830735_+\|tail	phage tail protein	W8CYY9	Bacillus_phage	1.0e-277	92.7
WP_069355000.1\|830731_834757_+	hypothetical protein	H0USX5	Bacillus_phage	0.0e+00	94.2
WP_030026929.1\|834882_835107_+	hypothetical protein	A0A1B1P780	Bacillus_phage	7.0e-29	95.9
WP_069355001.1\|835181_835607_+\|holin	phage holin family protein	A0A1B1P787	Bacillus_phage	3.7e-71	98.6
WP_000542505.1\|835606_836425_+	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	4.7e-147	88.6
WP_069355002.1\|836483_836714_-	helix-turn-helix domain-containing protein	S5MBY6	Brevibacillus_phage	1.1e-08	40.3
WP_069355003.1\|837006_837420_+	hypothetical protein	A0A1B1P7T3	Bacillus_phage	3.7e-52	72.9
WP_069355004.1\|837432_837756_+	hypothetical protein	A0A1B1P7T1	Bacillus_phage	2.6e-40	75.0
WP_069355005.1\|837767_838934_+	DNA translocase FtsK	W8CYG2	Bacillus_phage	2.5e-202	90.7
WP_069355006.1\|838923_839532_+	hypothetical protein	A0A0S2GLL8	Bacillus_phage	1.9e-108	95.5
WP_069355007.1\|839536_840418_-	HTH domain-containing protein	I7ILW0	Bacillus_phage	3.2e-157	98.3
WP_000373756.1\|840915_842088_+	amino acid deaminase/aldolase	NA	NA	NA	NA
840758:840777	attR	NA	NA	NA	NA
WP_064532063.1\|842075_843392_+	FAD-binding protein	NA	NA	NA	NA
WP_000128025.1\|843445_844597_-	VanZ family protein	NA	NA	NA	NA
WP_001268332.1\|844768_844972_+	hypothetical protein	NA	NA	NA	NA
WP_053565233.1\|845092_845380_-	hypothetical protein	NA	NA	NA	NA
WP_000434794.1\|845559_846372_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_000495032.1\|846508_847450_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.3e-11	32.4
WP_053565232.1\|847670_848942_+	cell wall-binding protein	A0A0S2SXZ8	Bacillus_phage	5.4e-33	64.7
WP_000154019.1\|849054_849273_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_053565231.1\|849265_849739_+	hypothetical protein	NA	NA	NA	NA
WP_069355008.1\|849855_850488_+	class A sortase	NA	NA	NA	NA
WP_069355009.1\|851733_853119_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	4.9e-64	32.7
WP_069355010.1\|853372_854674_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_069355011.1\|854815_856537_+	DUF2339 domain-containing protein	NA	NA	NA	NA
WP_069355012.1\|856572_858120_-	DNA-binding protein	NA	NA	NA	NA
WP_001164892.1\|858300_859692_-	amino acid permease	NA	NA	NA	NA
WP_069355013.1\|859972_861265_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	4.5e-43	31.4
WP_000816201.1\|861443_861707_+	MerR family transcriptional regulator	Q331V0	Clostridium_botulinum_C_phage	3.8e-18	32.0
WP_063535666.1\|861703_862861_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q331V1	Clostridium_botulinum_C_phage	3.2e-125	60.9

DBSCAN-SWA_4

1154778 : 1253962

103

Bacillus_phage(55.56%)

holin,terminase,transposase,capsid,protease,tail,head,portal,integrase

attL 1150965:1150986|attR 1225278:1225299

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1150965:1150986	attL	NA	NA	NA	NA
WP_157452921.1\|1154778_1155678_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|1155632_1155902_-\|transposase	transposase	NA	NA	NA	NA
WP_000991356.1\|1155979_1156231_-	hypothetical protein	NA	NA	NA	NA
WP_065228404.1\|1156644_1157175_+	general stress protein	NA	NA	NA	NA
WP_000635853.1\|1157314_1157518_+	DUF4028 domain-containing protein	NA	NA	NA	NA
WP_000637511.1\|1157660_1157972_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_069355110.1\|1158566_1158872_-	hypothetical protein	NA	NA	NA	NA
WP_080497259.1\|1158989_1159985_-	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_069355112.1\|1160157_1161144_+	choloylglycine hydrolase family protein	M1HS66	Paramecium_bursaria_Chlorella_virus	3.5e-32	28.9
WP_000273536.1\|1161265_1161406_-	YflJ family protein	G3MBD1	Bacillus_virus	6.1e-07	63.4
WP_069355113.1\|1161560_1161923_+	hypothetical protein	NA	NA	NA	NA
WP_000539552.1\|1161949_1162135_-	hypothetical protein	NA	NA	NA	NA
WP_069355114.1\|1162343_1163585_+	DNA repair exonuclease	NA	NA	NA	NA
WP_069355115.1\|1163581_1166506_+	AAA family ATPase	NA	NA	NA	NA
WP_069355116.1\|1166547_1167504_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
WP_069355117.1\|1167523_1168681_-\|integrase	site-specific integrase	A0A0M5M609	Bacillus_phage	9.4e-202	88.8
WP_069355118.1\|1168739_1169165_-	ImmA/IrrE family metallo-endopeptidase	A0A1C8E988	Bacillus_phage	5.0e-76	97.9
WP_000102963.1\|1169180_1169603_-	helix-turn-helix transcriptional regulator	A0A0M4QX29	Bacillus_phage	2.2e-52	75.0
WP_069355119.1\|1169872_1170055_+	helix-turn-helix transcriptional regulator	A0A1C8E998	Bacillus_phage	2.0e-21	85.0
WP_000127561.1\|1170057_1170330_+	DUF771 domain-containing protein	A0A1C8E9B3	Bacillus_phage	2.0e-46	98.9
WP_069355120.1\|1170514_1171267_+	antirepressor	A0A2H4JBC7	uncultured_Caudovirales_phage	4.8e-106	81.0
WP_001186272.1\|1171278_1171467_+	hypothetical protein	A0A2H4J4V8	uncultured_Caudovirales_phage	6.1e-26	96.8
WP_069355121.1\|1171493_1171928_+	replication terminator protein	A0A0S2MVA8	Bacillus_phage	1.4e-73	99.3
WP_000178946.1\|1171945_1172659_+	hypothetical protein	A0A0S2MV99	Bacillus_phage	1.9e-128	99.6
WP_038413184.1\|1172658_1172874_+	hypothetical protein	A0A1C8E9A6	Bacillus_phage	3.6e-30	94.4
WP_069355122.1\|1172806_1173145_+	hypothetical protein	A0A0S2MVH7	Bacillus_phage	6.4e-50	96.4
WP_069355123.1\|1173238_1174174_+	DnaD domain protein	A0A0S2MVA0	Bacillus_phage	9.4e-144	84.9
WP_069355124.1\|1174185_1174665_+	hypothetical protein	A0A0S2MV74	Bacillus_phage	1.7e-80	93.1
WP_065485659.1\|1174657_1174888_+	hypothetical protein	A0A1C8E9C2	Bacillus_phage	1.3e-33	98.7
WP_069355125.1\|1175503_1175938_+	hypothetical protein	A0A2H4JBD8	uncultured_Caudovirales_phage	1.5e-75	94.4
WP_065485656.1\|1176062_1176599_+	dUTPase	A0A2H4J4W9	uncultured_Caudovirales_phage	4.5e-90	91.0
WP_069355126.1\|1176778_1177249_-	hypothetical protein	NA	NA	NA	NA
WP_065485654.1\|1178576_1178789_+	hypothetical protein	D2XR53	Bacillus_phage	2.4e-15	57.5
WP_113732895.1\|1179093_1179207_+	DUF3983 domain-containing protein	A0A1B0T6D3	Bacillus_phage	4.2e-06	77.8
WP_069355127.1\|1179497_1179974_+	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	9.2e-71	91.2
WP_069354777.1\|1180028_1181324_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-09	27.1
WP_069354776.1\|1181313_1182066_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	7.8e-56	46.9
WP_069355128.1\|1182173_1182455_+\|integrase	tyrosine-type recombinase/integrase	W8CYP1	Bacillus_phage	3.9e-37	87.0
WP_065485648.1\|1182914_1183133_+	hypothetical protein	H0USV5	Bacillus_phage	5.2e-21	66.2
WP_069356614.1\|1183525_1184023_-	hypothetical protein	NA	NA	NA	NA
WP_000377847.1\|1185483_1185759_+	hypothetical protein	H0USV6	Bacillus_phage	4.0e-18	53.8
WP_069355129.1\|1186558_1186867_+	hypothetical protein	A0A288WFY9	Bacillus_phage	7.2e-16	45.5
WP_065485642.1\|1186882_1187218_+	alpha/beta hydrolase	D2XR61	Bacillus_phage	6.8e-52	89.2
WP_069355130.1\|1187339_1187651_+\|terminase	terminase	D2XR14	Bacillus_phage	4.7e-39	86.3
WP_069355131.1\|1187647_1189315_+\|terminase	terminase large subunit	D2XR15	Bacillus_phage	3.7e-308	92.4
WP_069355132.1\|1189326_1190487_+\|portal	phage portal protein	D2XR16	Bacillus_phage	1.1e-173	82.5
WP_069355133.1\|1190470_1191253_+\|protease	Clp protease ClpP	A0A0A7RWX3	Clostridium_phage	5.1e-58	58.6
WP_069355134.1\|1191256_1192411_+\|capsid	phage major capsid protein	A0A2H4JHU0	uncultured_Caudovirales_phage	2.7e-201	92.2
WP_069355135.1\|1192416_1192710_+	hypothetical protein	D2XR19	Bacillus_phage	1.0e-43	90.7
WP_069355136.1\|1192711_1193065_+\|head	phage head closure protein	A0A2H4JGG7	uncultured_Caudovirales_phage	1.3e-56	93.1
WP_069355137.1\|1193066_1193411_+	HK97 gp10 family phage protein	D2XR21	Bacillus_phage	2.8e-53	94.6
WP_069355138.1\|1193407_1193737_+	hypothetical protein	D2XR22	Bacillus_phage	1.1e-51	90.8
WP_069355139.1\|1193737_1194331_+\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	2.2e-101	91.3
WP_000415935.1\|1194337_1194694_+	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	5.7e-41	70.8
WP_069355140.1\|1194924_1196157_+	hypothetical protein	A0A2H4JAI2	uncultured_Caudovirales_phage	5.9e-186	85.6
WP_069356615.1\|1196434_1198828_+	hypothetical protein	A0A2H4JC82	uncultured_Caudovirales_phage	1.3e-35	40.5
WP_069355141.1\|1198864_1200337_+\|tail	phage tail protein	D2XPZ5	Bacillus_virus	7.7e-217	71.5
WP_069355142.1\|1200333_1206036_+	peptidase S74	D2XR28	Bacillus_phage	0.0e+00	44.7
WP_069355143.1\|1206075_1206501_+\|holin	phage holin family protein	A0A0S2MVC4	Bacillus_phage	7.0e-70	96.5
WP_069355144.1\|1206500_1207436_+	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	8.8e-150	80.1
WP_069355145.1\|1207573_1208296_-	geobacillin-26 family protein	NA	NA	NA	NA
WP_084746347.1\|1210343_1212023_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	9.3e-49	33.9
WP_069356616.1\|1212114_1212948_-	cytosolic protein	A0A2H4J6G7	uncultured_Caudovirales_phage	2.6e-121	82.3
WP_069355149.1\|1213608_1213941_+	DUF1904 family protein	NA	NA	NA	NA
WP_069354786.1\|1214810_1215923_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069355150.1\|1216026_1216605_-	LysE family translocator	NA	NA	NA	NA
WP_069355151.1\|1217444_1218389_+	ring-cleaving dioxygenase	NA	NA	NA	NA
WP_001072581.1\|1218433_1219411_+	ring-cleaving dioxygenase	NA	NA	NA	NA
WP_069355152.1\|1219687_1220785_+	histidine kinase	A0A2H4J8G3	uncultured_Caudovirales_phage	2.9e-91	49.2
WP_000723609.1\|1220785_1220989_+	hypothetical protein	NA	NA	NA	NA
WP_069355153.1\|1221230_1222103_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000449223.1\|1222181_1222382_+	hypothetical protein	NA	NA	NA	NA
WP_000554479.1\|1222596_1223448_+	DUF2935 domain-containing protein	G5CQX5	Megavirus	1.5e-07	26.2
WP_069355154.1\|1223903_1225100_+	oxalate decarboxylase family bicupin	NA	NA	NA	NA
WP_069355155.1\|1225483_1225933_+	helix-turn-helix transcriptional regulator	X2CXD8	Lactobacillus_phage	7.5e-06	34.9
1225278:1225299	attR	NA	NA	NA	NA
WP_000394286.1\|1226030_1226591_+	glycerol uptake operon antiterminator GlpP	NA	NA	NA	NA
WP_001272200.1\|1226819_1227641_+	glycerol uptake facilitator protein GlpF	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	5.2e-29	36.7
WP_000760011.1\|1227654_1229145_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_029442064.1\|1229278_1230961_+	aerobic glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_069355156.1\|1231518_1232586_-	hypothetical protein	NA	NA	NA	NA
WP_084746010.1\|1233228_1233801_+	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_069355158.1\|1233819_1234230_+	DUF2283 domain-containing protein	NA	NA	NA	NA
WP_069355159.1\|1234972_1235506_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_069355160.1\|1235510_1235918_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_069355161.1\|1235925_1237179_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_069354786.1\|1237364_1238477_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_053565080.1\|1238859_1239423_-	hypothetical protein	NA	NA	NA	NA
WP_069355162.1\|1239509_1241840_-	AAA family ATPase	NA	NA	NA	NA
WP_069355163.1\|1242117_1242363_+	cytoplasmic protein	NA	NA	NA	NA
WP_064532786.1\|1242566_1243439_-	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_000172690.1\|1243882_1244077_-	hypothetical protein	NA	NA	NA	NA
WP_069355164.1\|1244192_1244528_+	DUF1878 family protein	NA	NA	NA	NA
WP_000834924.1\|1244533_1245091_-	HTH-type transcriptional regulator Hpr	NA	NA	NA	NA
WP_000030302.1\|1245389_1245752_-	general stress protein	NA	NA	NA	NA
WP_001016835.1\|1245933_1246368_-	HIT family protein	X4YH05	Lactococcus_phage	1.6e-05	30.5
WP_053565078.1\|1246930_1247674_+	ABC transporter ATP-binding protein EcsA	A0A2H4PQG7	Staphylococcus_phage	8.3e-26	29.3
WP_069355165.1\|1247666_1248878_+	ABC transporter permease EcsB	NA	NA	NA	NA
WP_069355166.1\|1248891_1249599_+	ecs operon protein EcsC	NA	NA	NA	NA
WP_069355167.1\|1249710_1250028_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000902681.1\|1250138_1250453_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001996881.1\|1250991_1251240_-	hypothetical protein	NA	NA	NA	NA
WP_063546722.1\|1251380_1252634_+	DUF2974 domain-containing protein	NA	NA	NA	NA
WP_069354786.1\|1252849_1253962_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1422059 : 1540870

114

Bacillus_phage(36.0%)

bacteriocin,transposase,coat,protease,integrase

attL 1476792:1476851|attR 1539640:1541225

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069355219.1\|1422059_1422530_-\|coat	spore coat protein CotY	NA	NA	NA	NA
WP_053565002.1\|1422672_1424739_-	ATP-dependent helicase	A0A068EQC7	Bacillus_phage	6.2e-79	31.9
WP_000543305.1\|1424838_1425261_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000765871.1\|1425262_1425781_-	hypothetical protein	NA	NA	NA	NA
WP_053565000.1\|1425874_1426606_-	esterase family protein	NA	NA	NA	NA
WP_069355220.1\|1426810_1427722_+	DMT family transporter	NA	NA	NA	NA
WP_069355221.1\|1428214_1428613_-	hypothetical protein	NA	NA	NA	NA
WP_053564997.1\|1428768_1430247_-	sodium/proline symporter PutP	NA	NA	NA	NA
WP_069355222.1\|1431277_1432696_+	anthranilate synthase component I	NA	NA	NA	NA
WP_065482727.1\|1432692_1433280_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.8e-47	47.9
WP_053564994.1\|1433276_1434302_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.3e-50	34.5
WP_069355223.1\|1434303_1435065_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	2.4e-36	40.6
WP_069355224.1\|1435061_1435676_+	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
WP_069355225.1\|1435672_1436866_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_069355226.1\|1436869_1437646_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000946150.1\|1437719_1438079_+	DUF4029 domain-containing protein	NA	NA	NA	NA
WP_064532940.1\|1438193_1439693_+	lactate permease	NA	NA	NA	NA
WP_064532942.1\|1439783_1440467_+	YukJ family protein	NA	NA	NA	NA
WP_000424522.1\|1440481_1441315_-	hypothetical protein	NA	NA	NA	NA
WP_069355227.1\|1441511_1442297_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_069355228.1\|1442316_1443552_+	YARHG domain-containing protein	NA	NA	NA	NA
WP_065482744.1\|1443590_1444019_-	hypothetical protein	NA	NA	NA	NA
WP_001110229.1\|1444219_1445554_+	CoA-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	4.4e-17	27.0
WP_064532952.1\|1445654_1446143_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000996808.1\|1446439_1446850_+	DUF3908 domain-containing protein	NA	NA	NA	NA
WP_064532956.1\|1447561_1449103_-	SagB/ThcOx family dehydrogenase	NA	NA	NA	NA
WP_064532958.1\|1449118_1451068_-	TOMM precursor leader peptide-binding protein	NA	NA	NA	NA
WP_064532960.1\|1451064_1452984_-\|bacteriocin	putative thiazole-containing bacteriocin maturation protein	NA	NA	NA	NA
WP_000569893.1\|1453107_1454367_-	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_069355229.1\|1454500_1457368_-	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_069355230.1\|1458191_1458401_+	helix-turn-helix transcriptional regulator	S5M643	Brevibacillus_phage	2.3e-05	39.3
WP_048564894.1\|1458403_1458781_+	hypothetical protein	NA	NA	NA	NA
WP_001178303.1\|1458809_1458992_+	DUF3976 domain-containing protein	NA	NA	NA	NA
WP_069355231.1\|1459125_1459488_+	hypothetical protein	NA	NA	NA	NA
WP_001169495.1\|1459912_1460509_+	DUF4878 domain-containing protein	NA	NA	NA	NA
WP_000834471.1\|1461194_1461356_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_000054715.1\|1461388_1462288_+	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.8e-14	26.5
WP_069355233.1\|1462280_1463522_+	ABC transporter permease	NA	NA	NA	NA
WP_069355234.1\|1464238_1464505_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069355235.1\|1464523_1465144_+	hypothetical protein	NA	NA	NA	NA
WP_069355236.1\|1465144_1465450_+	hypothetical protein	NA	NA	NA	NA
WP_069355237.1\|1465485_1465704_+	hypothetical protein	NA	NA	NA	NA
WP_069355238.1\|1465720_1466110_+	adenylate kinase	NA	NA	NA	NA
WP_083594897.1\|1466641_1467193_-	hypothetical protein	NA	NA	NA	NA
WP_069355240.1\|1467982_1468816_+	hypothetical protein	NA	NA	NA	NA
WP_084746025.1\|1468794_1469211_+	DUF4263 domain-containing protein	NA	NA	NA	NA
WP_083594900.1\|1469382_1471269_+	AAA family ATPase	E5E3R2	Burkholderia_phage	3.0e-11	22.7
WP_069354784.1\|1471555_1471825_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|1471779_1472679_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_071720110.1\|1473078_1473327_+	hypothetical protein	NA	NA	NA	NA
WP_069355243.1\|1473420_1473777_-	hypothetical protein	NA	NA	NA	NA
WP_069355244.1\|1473954_1474224_-	hypothetical protein	NA	NA	NA	NA
WP_157452921.1\|1475167_1476067_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|1476021_1476291_-\|transposase	transposase	NA	NA	NA	NA
1476792:1476851	attL	NA	NA	NA	NA
WP_069354786.1\|1476909_1478022_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069355247.1\|1478876_1479107_-	hypothetical protein	NA	NA	NA	NA
WP_069355248.1\|1479361_1479595_-	hypothetical protein	NA	NA	NA	NA
WP_069355249.1\|1479913_1481179_-	DEAD/DEAH box helicase family protein	A0A1P8CWT6	Bacillus_phage	3.2e-78	42.4
WP_069354782.1\|1482115_1483411_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.5e-11	27.5
WP_069354783.1\|1483400_1484153_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	3.5e-56	46.5
WP_084746028.1\|1484149_1485079_-\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	5.7e-24	25.3
WP_069355251.1\|1485542_1486010_-	hypothetical protein	NA	NA	NA	NA
WP_053564957.1\|1486617_1486839_-	hypothetical protein	NA	NA	NA	NA
WP_069355252.1\|1487006_1487762_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000251856.1\|1488283_1488511_+	hypothetical protein	NA	NA	NA	NA
WP_069355253.1\|1488663_1489950_+	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_000767792.1\|1490141_1490711_+	signal peptidase I	NA	NA	NA	NA
WP_000172852.1\|1490773_1491361_+	cell division protein FtsN	NA	NA	NA	NA
WP_069355254.1\|1491495_1492338_+	DUF4047 domain-containing protein	NA	NA	NA	NA
WP_069355255.1\|1492724_1493318_+	camelysin	NA	NA	NA	NA
WP_000578885.1\|1493357_1493681_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000276219.1\|1493760_1493895_-	DNA-binding anti-repressor SinI	NA	NA	NA	NA
WP_069355256.1\|1494237_1496625_+\|protease	M6 family metalloprotease domain-containing protein	NA	NA	NA	NA
WP_069355257.1\|1496796_1498164_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000720333.1\|1498403_1499387_+	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	2.7e-24	37.1
WP_069355258.1\|1499383_1500232_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	8.6e-11	23.3
WP_000714190.1\|1500238_1501039_+	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
WP_069355259.1\|1501077_1502127_+	spermidine/putrescine ABC transporter substrate-binding protein PotD	NA	NA	NA	NA
WP_016513124.1\|1502186_1502834_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_069355260.1\|1502945_1505138_+	MMPL family transporter	NA	NA	NA	NA
WP_000490302.1\|1505240_1505657_+	hypothetical protein	NA	NA	NA	NA
WP_069355261.1\|1505757_1506681_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000599010.1\|1506772_1507378_+	DUF1648 domain-containing protein	NA	NA	NA	NA
WP_016513122.1\|1507418_1508246_-	hypothetical protein	U5Q0C0	Bacillus_phage	3.7e-43	67.7
WP_157452921.1\|1509260_1510160_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|1510114_1510384_-\|transposase	transposase	NA	NA	NA	NA
WP_084746362.1\|1511265_1512681_-	glycolate oxidase subunit GlcD	NA	NA	NA	NA
WP_069355262.1\|1512791_1513907_-	carbohydrate diacid regulator	NA	NA	NA	NA
WP_069355263.1\|1514043_1515018_+	YVTN family beta-propeller repeat-containing protein	NA	NA	NA	NA
WP_001046397.1\|1515010_1515682_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.6e-52	44.8
WP_053564942.1\|1515685_1517086_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	5.0e-40	34.5
WP_071714541.1\|1517438_1518158_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_000869147.1\|1518326_1519046_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_000061930.1\|1519062_1520484_+	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_000147182.1\|1520483_1521194_+	lactate utilization protein C	NA	NA	NA	NA
WP_069355264.1\|1521306_1522029_+	prepilin peptidase	NA	NA	NA	NA
WP_069355265.1\|1522043_1522355_+	hypothetical protein	A0A109QIR8	Bacillus_phage	4.3e-08	33.0
WP_000893034.1\|1522382_1523234_-	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_069355266.1\|1523436_1524237_-	TerC family protein	A0A068EP98	Bacillus_phage	1.6e-27	39.5
WP_069355267.1\|1524531_1525851_-	potassium transporter TrkH	NA	NA	NA	NA
WP_000241212.1\|1525965_1526151_-	alpha/beta-type small acid-soluble spore protein	A0A1P8CX76	Bacillus_phage	2.4e-14	70.7
WP_001067916.1\|1526299_1526743_-	MaoC family dehydratase	NA	NA	NA	NA
WP_000448592.1\|1526844_1527369_-	polyhydroxyalkanoic acid inclusion protein PhaP	NA	NA	NA	NA
WP_000939954.1\|1527411_1527864_-	poly-beta-hydroxybutyrate-responsive repressor	NA	NA	NA	NA
WP_000566941.1\|1528062_1528545_+	polyhydroxyalkanoic acid synthase subunit PhaR	NA	NA	NA	NA
WP_000250407.1\|1528695_1529439_+	acetoacetyl-CoA reductase	Q06VL0	Trichoplusia_ni_ascovirus	3.2e-17	30.0
WP_000206336.1\|1529522_1530608_+	class III poly(R)-hydroxyalkanoic acid synthase subunit PhaC	NA	NA	NA	NA
WP_000772526.1\|1530702_1531896_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_001204706.1\|1531919_1533269_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_069355268.1\|1533307_1533643_-	DUF3905 domain-containing protein	NA	NA	NA	NA
WP_000750893.1\|1534172_1535249_+	putative 2-aminoethylphosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000006196.1\|1535268_1536270_+	putative 2-aminoethylphosphonate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.6e-30	36.3
WP_069355269.1\|1538049_1538844_+	phosphonoacetaldehyde hydrolase	NA	NA	NA	NA
WP_069354786.1\|1539757_1540870_+\|transposase	IS110 family transposase	NA	NA	NA	NA
1539640:1541225	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2047763 : 2106065

Bacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069355414.1\|2047763_2048909_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.3e-41	28.5
WP_069355415.1\|2049170_2050136_-	arsenic resistance protein	NA	NA	NA	NA
WP_000522528.1\|2050429_2051122_+	FMN-dependent NADH-azoreductase	NA	NA	NA	NA
WP_001284784.1\|2051360_2052716_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_000750850.1\|2052801_2053221_+	VOC family protein	NA	NA	NA	NA
WP_069355416.1\|2053550_2055200_+	copper resistance protein	NA	NA	NA	NA
WP_065228652.1\|2055234_2055855_+	DUF1775 domain-containing protein	NA	NA	NA	NA
WP_023521703.1\|2055897_2056803_-	DMT family transporter	NA	NA	NA	NA
WP_069355417.1\|2056900_2057770_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000704073.1\|2057891_2058323_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_000216673.1\|2058393_2059044_+	DsbA family oxidoreductase	NA	NA	NA	NA
WP_001277021.1\|2059101_2059704_+	nitroreductase family protein	NA	NA	NA	NA
WP_069355419.1\|2060839_2061928_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q332I1	Clostridium_botulinum_C_phage	2.5e-140	68.7
WP_001006602.1\|2062605_2063619_+	AI-2E family transporter	NA	NA	NA	NA
WP_000715322.1\|2063707_2064652_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_069355421.1\|2064852_2066289_+	flavin monoamine oxidase family protein	NA	NA	NA	NA
WP_001044939.1\|2066395_2067319_+	GTP-binding protein	NA	NA	NA	NA
WP_000062000.1\|2067581_2068799_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000149338.1\|2068888_2069662_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	4.4e-14	27.2
WP_001196696.1\|2069639_2070341_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.5e-13	31.3
WP_000382788.1\|2070362_2071223_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_002083259.1\|2071272_2072226_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_069355414.1\|2072447_2073593_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.3e-41	28.5
WP_000404994.1\|2073887_2074676_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_053564740.1\|2074796_2075345_+	DUF4865 family protein	NA	NA	NA	NA
WP_053564739.1\|2075388_2075808_+	tautomerase family protein	NA	NA	NA	NA
WP_069355422.1\|2075797_2076070_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_001205523.1\|2076274_2076718_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_069355423.1\|2076838_2077894_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_069355424.1\|2078486_2079890_+	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_069355425.1\|2079876_2080893_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_069355426.1\|2080892_2082614_+	thiol reductant ABC exporter subunit CydD	W8CYL7	Bacillus_phage	3.3e-25	24.3
WP_069355427.1\|2082610_2084335_+	thiol reductant ABC exporter subunit CydC	A0A2H4UU96	Bodo_saltans_virus	1.1e-20	25.1
WP_069355428.1\|2084467_2085616_+	hypothetical protein	NA	NA	NA	NA
WP_069355429.1\|2085723_2088285_+	glycosyltransferase	A0A1V0SAH6	Catovirus	5.8e-10	31.1
WP_069355430.1\|2088304_2089435_+	DegT/DnrJ/EryC1/StrS family aminotransferase	NA	NA	NA	NA
WP_053564731.1\|2089427_2089994_+	acyltransferase	NA	NA	NA	NA
WP_000459099.1\|2090178_2090400_+	hypothetical protein	NA	NA	NA	NA
WP_000695203.1\|2090490_2090937_+	hypothetical protein	NA	NA	NA	NA
WP_069355431.1\|2091265_2092267_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_053564729.1\|2092473_2093427_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	4.2e-22	29.2
WP_001029924.1\|2093676_2094276_+	nitroreductase family protein	NA	NA	NA	NA
WP_001244281.1\|2094322_2094493_-	hypothetical protein	NA	NA	NA	NA
WP_069355432.1\|2095179_2096466_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.8e-10	30.6
WP_084746073.1\|2097008_2098304_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.5e-11	27.5
WP_069355433.1\|2098293_2098626_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.2e-11	40.8
WP_069354784.1\|2098677_2098947_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|2098901_2099801_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069355434.1\|2100988_2102749_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.1e-273	98.0
WP_069356626.1\|2102789_2103467_+	response regulator transcription factor	W8CYM9	Bacillus_phage	5.6e-122	98.7
WP_053564723.1\|2104561_2105149_-	DUF3139 domain-containing protein	NA	NA	NA	NA
WP_000818985.1\|2105345_2106065_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0

DBSCAN-SWA_7

2510480 : 2554860

Bacillus_phage(28.57%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069355583.1\|2510480_2511377_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_142238912.1\|2511376_2512036_+	chloramphenicol acetyltransferase	NA	NA	NA	NA
WP_053564524.1\|2512292_2512898_+	CTP synthase	NA	NA	NA	NA
WP_069355584.1\|2512968_2513835_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000591705.1\|2513964_2515008_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000093107.1\|2515086_2515518_-	hypothetical protein	NA	NA	NA	NA
WP_069355585.1\|2515804_2516929_+	choloylglycine hydrolase	NA	NA	NA	NA
WP_142238913.1\|2516980_2517244_+	hypothetical protein	NA	NA	NA	NA
WP_069355586.1\|2517340_2518243_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_069354786.1\|2518454_2519567_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_001262982.1\|2519977_2520667_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_069355587.1\|2520925_2521813_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_053564519.1\|2521846_2522443_+	DUF1349 domain-containing protein	NA	NA	NA	NA
WP_053564518.1\|2522664_2524419_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.9e-47	28.7
WP_069355588.1\|2524411_2526208_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.2e-55	28.3
WP_001257871.1\|2526876_2527380_-	hypothetical protein	NA	NA	NA	NA
WP_001123247.1\|2527765_2528050_-	DUF4183 domain-containing protein	NA	NA	NA	NA
WP_000774115.1\|2528292_2528565_-	hypothetical protein	NA	NA	NA	NA
WP_069354783.1\|2528907_2529660_-	AAA family ATPase	A0A059NT77	Lactococcus_phage	3.5e-56	46.5
WP_069354782.1\|2529649_2530945_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.5e-11	27.5
WP_053564517.1\|2531140_2531923_-	glycosyltransferase family 2 protein	A0A1V0SJD8	Klosneuvirus	1.2e-22	32.1
WP_069355589.1\|2532102_2532687_-	LysE family transporter	NA	NA	NA	NA
WP_130813712.1\|2532742_2533357_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069355590.1\|2533723_2534293_-	collagen-like protein	NA	NA	NA	NA
WP_157452945.1\|2534545_2535313_+	DUF4183 domain-containing protein	NA	NA	NA	NA
WP_069355592.1\|2535873_2537172_+	collagen-like repeat preface domain-containing protein	NA	NA	NA	NA
WP_000126322.1\|2537737_2538370_-	cupin domain-containing protein	NA	NA	NA	NA
WP_000010317.1\|2538599_2538905_+	hypothetical protein	NA	NA	NA	NA
WP_069355593.1\|2538998_2540309_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_069355594.1\|2540286_2541156_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_069356634.1\|2541651_2542245_+	methyltransferase domain-containing protein	A0A2P1JQT7	Mycobacterium_phage	1.0e-10	33.9
WP_000137396.1\|2542558_2543671_+	toxic anion resistance protein	NA	NA	NA	NA
WP_069355595.1\|2543695_2544529_+	DUF3974 domain-containing protein	NA	NA	NA	NA
WP_069355596.1\|2544586_2546146_-	family 10 glycosylhydrolase	NA	NA	NA	NA
WP_069355597.1\|2546373_2546679_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_001032277.1\|2546690_2547974_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_001021962.1\|2548052_2548319_+	hypothetical protein	NA	NA	NA	NA
WP_069354786.1\|2549017_2550130_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069355598.1\|2551284_2552412_+	alpha-helical pore-forming toxin family protein	NA	NA	NA	NA
WP_157452921.1\|2553736_2554636_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|2554590_2554860_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2643122 : 2755386

105

Bacillus_phage(61.9%)

bacteriocin,tRNA,transposase,terminase,capsid,protease,tail,head,portal,integrase

attL 2676558:2676574|attR 2749959:2749975

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053564423.1\|2643122_2643779_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_053564422.1\|2644097_2644301_+	hypothetical protein	NA	NA	NA	NA
WP_071730552.1\|2644328_2644571_-	hypothetical protein	NA	NA	NA	NA
WP_053564420.1\|2644681_2645608_+	alcohol dehydrogenase catalytic domain-containing protein	NA	NA	NA	NA
WP_053564419.1\|2645689_2646547_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_053564418.1\|2646602_2647100_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_069355627.1\|2647358_2647988_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_053564416.1\|2648240_2648942_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_053564415.1\|2648938_2649841_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_053564414.1\|2649982_2650153_+	DUF2197 domain-containing protein	NA	NA	NA	NA
WP_053564413.1\|2650560_2652114_+\|tRNA	lysine--tRNA ligase	NA	NA	NA	NA
WP_001128402.1\|2652173_2652602_-	cell wall hydrolase	NA	NA	NA	NA
WP_017656684.1\|2652752_2653667_+	acetamidase/formamidase family protein	NA	NA	NA	NA
WP_069355628.1\|2653794_2654502_+	response regulator transcription factor	NA	NA	NA	NA
WP_053564412.1\|2654498_2655482_+	sensor histidine kinase	NA	NA	NA	NA
WP_000376270.1\|2655801_2656428_-	hypothetical protein	NA	NA	NA	NA
WP_069356636.1\|2656985_2658614_+	ABC-F type ribosomal protection protein	A0A1B0RXA0	Streptococcus_phage	6.0e-53	33.4
WP_053564411.1\|2658634_2659228_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_053565503.1\|2659747_2660242_+	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_053564410.1\|2660558_2661329_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-32	39.9
WP_069355630.1\|2661303_2663238_+	ABC transporter permease	NA	NA	NA	NA
WP_053564408.1\|2663305_2663977_+	hypothetical protein	NA	NA	NA	NA
WP_053564407.1\|2664085_2664427_-	DUF3914 domain-containing protein	NA	NA	NA	NA
WP_053564406.1\|2664706_2665948_+	lipase	NA	NA	NA	NA
WP_053564405.1\|2666035_2667061_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_069355631.1\|2667150_2668599_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_003270605.1\|2668603_2669518_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_053564403.1\|2669824_2670514_+	thiaminase II	NA	NA	NA	NA
WP_002082716.1\|2670911_2671175_+	DUF3937 domain-containing protein	NA	NA	NA	NA
WP_069355632.1\|2671724_2672045_+\|bacteriocin	heterocycloanthracin/sonorensin family bacteriocin	NA	NA	NA	NA
WP_053564402.1\|2672539_2673025_+	hypothetical protein	NA	NA	NA	NA
WP_000736205.1\|2673336_2674038_+	DUF3962 domain-containing protein	NA	NA	NA	NA
WP_046392720.1\|2674076_2675186_-\|integrase	site-specific integrase	A0A0U3U8Y8	Bacillus_phage	4.1e-146	78.4
WP_069355633.1\|2675832_2677035_+	hypothetical protein	D2XQ10	Bacillus_virus	1.2e-82	46.2
2676558:2676574	attL	NA	NA	NA	NA
WP_071740166.1\|2677031_2677217_+	hypothetical protein	NA	NA	NA	NA
WP_000425256.1\|2677477_2677828_-	helix-turn-helix transcriptional regulator	A0A288WFW4	Bacillus_phage	7.4e-17	39.7
WP_061139252.1\|2678011_2678308_+	helix-turn-helix transcriptional regulator	A0A288WG89	Bacillus_phage	1.1e-08	46.5
WP_000522024.1\|2678523_2678790_+	helix-turn-helix domain-containing protein	A0A0U3ULL9	Bacillus_phage	1.6e-35	90.6
WP_000190248.1\|2679164_2679911_+	DnaD domain protein	A0A1B0T6C0	Bacillus_phage	4.2e-78	79.9
WP_084746103.1\|2679849_2680725_+	ATP-binding protein	Q2I8C8	Bacillus_phage	1.7e-62	45.5
WP_069355634.1\|2680740_2680935_+	hypothetical protein	A0A1B1P7U7	Bacillus_phage	4.3e-27	90.6
WP_000805171.1\|2680960_2681134_+	DUF3954 domain-containing protein	A0A1B1P7U5	Bacillus_phage	1.8e-24	98.2
WP_069355635.1\|2681148_2681403_+	hypothetical protein	A0A0U3SU43	Bacillus_phage	1.1e-35	84.5
WP_053564389.1\|2681417_2681630_+	hypothetical protein	A0A1B0T6B5	Bacillus_phage	4.3e-20	79.0
WP_069355636.1\|2681778_2682375_-	exosporium leader peptide-containing protein	NA	NA	NA	NA
WP_053564388.1\|2682563_2682923_-	cell division protein DivIVC	NA	NA	NA	NA
WP_016124630.1\|2684119_2685289_+	hypothetical protein	F2Y2K8	Organic_Lake_phycodnavirus	8.5e-09	27.0
WP_016124632.1\|2686162_2686819_+	hypothetical protein	NA	NA	NA	NA
WP_000166181.1\|2687175_2687658_+	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	1.1e-71	83.1
WP_001012146.1\|2687657_2688200_+\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	2.9e-89	91.7
WP_016124636.1\|2688496_2688841_+	hypothetical protein	NA	NA	NA	NA
WP_069355637.1\|2689133_2689778_+	hypothetical protein	NA	NA	NA	NA
WP_069355638.1\|2690203_2690701_+	hypothetical protein	A0A288WFY4	Bacillus_phage	7.2e-34	46.4
WP_069355639.1\|2690837_2691116_+	hypothetical protein	NA	NA	NA	NA
WP_069354853.1\|2694437_2695583_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.7e-41	28.5
WP_069355640.1\|2695990_2696224_+	hypothetical protein	A0A0K2CZF4	Paenibacillus_phage	5.6e-05	41.3
WP_069355641.1\|2696220_2696601_-	DUF2513 domain-containing protein	A0A1Q1PVT8	Staphylococcus_phage	2.8e-17	42.6
WP_069355643.1\|2697057_2697393_+	HNH endonuclease	D2XR61	Bacillus_phage	8.3e-50	85.6
WP_069355644.1\|2697516_2697828_+\|terminase	terminase	D2XR14	Bacillus_phage	2.7e-39	84.3
WP_069355645.1\|2697824_2699492_+\|terminase	terminase large subunit	D2XR15	Bacillus_phage	9.4e-304	91.4
WP_046946472.1\|2699500_2700646_+\|portal	phage portal protein	D2XR16	Bacillus_phage	1.2e-180	87.0
WP_069356638.1\|2700645_2701389_+\|protease	Clp protease ClpP	D2XR17	Bacillus_phage	3.3e-131	97.6
WP_069355646.1\|2701392_2702547_+\|capsid	phage major capsid protein	A0A2H4JHU0	uncultured_Caudovirales_phage	9.4e-202	92.2
WP_001098851.1\|2702552_2702846_+	hypothetical protein	D2XR19	Bacillus_phage	2.0e-44	91.8
WP_069355647.1\|2702847_2703201_+\|head	phage head closure protein	A0A2H4JGG7	uncultured_Caudovirales_phage	1.5e-57	94.8
WP_069355648.1\|2703202_2703544_+	HK97 gp10 family phage protein	D2XR21	Bacillus_phage	2.6e-51	92.0
WP_069355649.1\|2703543_2703873_+	hypothetical protein	D2XR22	Bacillus_phage	4.8e-50	89.9
WP_069355650.1\|2703873_2704461_+\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	9.6e-86	81.0
WP_069355651.1\|2704465_2704828_+	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	1.1e-52	84.2
WP_069355652.1\|2705058_2708634_+	DUF2207 domain-containing protein	A0A2H4JAI2	uncultured_Caudovirales_phage	2.3e-190	87.6
WP_069355653.1\|2708675_2710151_+\|tail	phage tail protein	D2XR27	Bacillus_phage	3.5e-161	57.9
WP_069355654.1\|2710147_2715907_+	peptidase S74	D2XR28	Bacillus_phage	0.0e+00	45.3
WP_069355414.1\|2716079_2717225_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.3e-41	28.5
WP_069355655.1\|2717720_2721014_+	hypothetical protein	NA	NA	NA	NA
WP_053564349.1\|2721387_2723070_+	RNAseH domain-containing protein	NA	NA	NA	NA
WP_053564347.1\|2724189_2724606_+	DUF3995 domain-containing protein	NA	NA	NA	NA
WP_000878369.1\|2724726_2724930_+	hypothetical protein	NA	NA	NA	NA
WP_000362069.1\|2725258_2725471_-	hypothetical protein	NA	NA	NA	NA
WP_069355656.1\|2725680_2726685_+	DUF1835 domain-containing protein	NA	NA	NA	NA
WP_000282689.1\|2726830_2727235_+	hypothetical protein	NA	NA	NA	NA
WP_069355657.1\|2727394_2728630_+	cytochrome P450	NA	NA	NA	NA
WP_000106397.1\|2728897_2730181_+	MFS transporter	NA	NA	NA	NA
WP_069355658.1\|2730170_2730803_+	Vat family streptogramin A O-acetyltransferase	A0A2R8FE91	Brazilian_cedratvirus	1.6e-25	43.1
WP_000046095.1\|2730873_2731029_+	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_000289127.1\|2731131_2731629_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_069355659.1\|2731769_2732984_+	cytochrome P450	NA	NA	NA	NA
WP_023522059.1\|2733093_2733672_+	hypothetical protein	NA	NA	NA	NA
WP_000766393.1\|2733847_2734699_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_053564341.1\|2735121_2736909_+	PAS domain-containing protein	NA	NA	NA	NA
WP_069355660.1\|2737143_2739270_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_069355661.1\|2739346_2739877_+	signal peptidase I	NA	NA	NA	NA
WP_069355662.1\|2740135_2741323_+	UDP-glucosyltransferase	A0A2H4ZK81	Cryptophlebia_leucotreta_granulosis_virus	8.9e-06	26.2
WP_069355663.1\|2742468_2743017_+	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_069355664.1\|2743027_2744728_+	energy-coupling factor ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.0e-15	30.0
WP_069355665.1\|2744720_2745521_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000120182.1\|2745657_2745765_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_053564335.1\|2745857_2747126_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	4.1e-25	29.6
WP_071714916.1\|2747261_2747456_-\|integrase	tyrosine-type recombinase/integrase	A0A1B0T6A8	Bacillus_phage	6.7e-12	66.0
WP_000754941.1\|2747761_2747911_+	DUF3954 domain-containing protein	A0A1B0T6B8	Bacillus_phage	1.8e-09	63.6
WP_053564333.1\|2750400_2750808_-	DUF4870 domain-containing protein	NA	NA	NA	NA
2749959:2749975	attR	NA	NA	NA	NA
WP_053564332.1\|2751109_2751574_-	hypothetical protein	NA	NA	NA	NA
WP_000796393.1\|2751881_2752346_-	hypothetical protein	NA	NA	NA	NA
WP_069355666.1\|2752927_2753122_+	hypothetical protein	NA	NA	NA	NA
WP_069355667.1\|2753688_2753988_-	hypothetical protein	NA	NA	NA	NA
WP_069354786.1\|2754273_2755386_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

2780293 : 2824965

Wolbachia_phage(18.18%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069354853.1\|2780293_2781439_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.7e-41	28.5
WP_157452929.1\|2781793_2782462_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_000026312.1\|2782651_2782831_-	hypothetical protein	NA	NA	NA	NA
WP_000587696.1\|2782922_2783180_-	hypothetical protein	NA	NA	NA	NA
WP_069355682.1\|2783315_2784746_+	glucose dehydrogenase	NA	NA	NA	NA
WP_053564289.1\|2784938_2785511_+	hypothetical protein	NA	NA	NA	NA
WP_000185959.1\|2785543_2786107_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001048947.1\|2786184_2786565_+	nucleotide excision repair endonuclease	NA	NA	NA	NA
WP_069355683.1\|2786622_2786829_-	hypothetical protein	NA	NA	NA	NA
WP_069355684.1\|2786961_2787741_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_069355685.1\|2789060_2789588_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000999062.1\|2789604_2790126_+	bacillithiol transferase BstA	NA	NA	NA	NA
WP_069355686.1\|2790713_2791826_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000522472.1\|2792299_2792677_-	PH domain-containing protein	A6N235	Microbacterium_phage	5.5e-10	36.4
WP_053564294.1\|2793267_2793639_+	hypothetical protein	NA	NA	NA	NA
WP_157452930.1\|2793799_2793970_+	hypothetical protein	NA	NA	NA	NA
WP_001987779.1\|2794532_2794940_+	DUF1992 domain-containing protein	NA	NA	NA	NA
WP_069355687.1\|2795018_2795834_+	DUF1963 domain-containing protein	NA	NA	NA	NA
WP_069355688.1\|2796620_2797391_-	hypothetical protein	A0A0K2CNR4	Brevibacillus_phage	8.1e-16	31.9
WP_069355689.1\|2797687_2798383_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_053564299.1\|2798446_2799370_-	hypothetical protein	A0A1B1SHC5	Bacillus_phage	1.3e-76	52.0
WP_053564302.1\|2800475_2800901_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_069355414.1\|2802578_2803724_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.3e-41	28.5
WP_069355691.1\|2804039_2805056_-	serine hydrolase	NA	NA	NA	NA
WP_001071389.1\|2805157_2805424_-\|bacteriocin	heterocycloanthracin/sonorensin family bacteriocin	NA	NA	NA	NA
WP_069355692.1\|2805623_2806070_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_069355693.1\|2806086_2806434_-	divalent cation tolerance protein CutA	K7YGE2	Megavirus	1.6e-11	36.0
WP_069355694.1\|2806464_2806923_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_069355695.1\|2806999_2807923_-	nucleoside hydrolase	NA	NA	NA	NA
WP_069355696.1\|2809533_2810448_-	EamA family transporter	NA	NA	NA	NA
WP_069355697.1\|2810600_2812034_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_069355698.1\|2812078_2812609_-	DUF4269 domain-containing protein	NA	NA	NA	NA
WP_053564312.1\|2812775_2813237_+	DUF2306 domain-containing protein	NA	NA	NA	NA
WP_053564313.1\|2813370_2814216_-	SH3 domain-containing protein	A0A0S2MVR5	Bacillus_phage	1.6e-65	69.3
WP_069355699.1\|2814502_2815381_-	glycerophosphodiester phosphodiesterase	A0A076G4Q2	Staphylococcus_phage	8.3e-33	37.6
WP_053564315.1\|2815426_2816227_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_053564316.1\|2816738_2817443_+	hypothetical protein	NA	NA	NA	NA
WP_053564317.1\|2817492_2818137_-	DUF1295 domain-containing protein	NA	NA	NA	NA
WP_069355700.1\|2818159_2818957_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_069355701.1\|2819220_2820516_-	MFS transporter	NA	NA	NA	NA
WP_000703280.1\|2820628_2821852_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_069354782.1\|2822204_2823500_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.5e-11	27.5
WP_069355702.1\|2823489_2823840_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.1e-12	40.8
WP_157452921.1\|2823841_2824741_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|2824695_2824965_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_10

3243053 : 3292680

Bacillus_phage(28.57%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069354784.1\|3243053_3243323_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|3243277_3244177_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069355891.1\|3244328_3246185_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_001072312.1\|3246243_3246810_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_157452933.1\|3247221_3248655_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_069355892.1\|3248830_3249460_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_069355893.1\|3249488_3249653_+	DUF2197 domain-containing protein	NA	NA	NA	NA
WP_000651402.1\|3250076_3250886_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000577091.1\|3251747_3252194_-	hypothetical protein	NA	NA	NA	NA
WP_069355896.1\|3253443_3254208_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.1e-20	32.4
WP_001178563.1\|3254377_3254818_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_000501367.1\|3254986_3256192_-	M20 family metallopeptidase	NA	NA	NA	NA
WP_069355897.1\|3256458_3258768_-	AAA family ATPase	NA	NA	NA	NA
WP_001145268.1\|3258879_3259272_+	VOC family protein	NA	NA	NA	NA
WP_000656651.1\|3259572_3259806_-	hypothetical protein	NA	NA	NA	NA
WP_053564027.1\|3260209_3261301_+	low temperature requirement protein A	NA	NA	NA	NA
WP_000833211.1\|3262118_3262472_-	YxeA family protein	A0A0K2CYS5	Paenibacillus_phage	2.2e-13	38.0
WP_069355898.1\|3264959_3265700_-	YrrS family protein	NA	NA	NA	NA
WP_002094078.1\|3265937_3266372_-	hypothetical protein	NA	NA	NA	NA
WP_069355899.1\|3266925_3268239_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_069355900.1\|3268662_3269118_-	hypothetical protein	NA	NA	NA	NA
WP_000956453.1\|3269117_3269312_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069355901.1\|3269513_3270920_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_069355902.1\|3271293_3273378_-	serine hydrolase	NA	NA	NA	NA
WP_069356645.1\|3273469_3274636_-	serine hydrolase	A0A1D8EXR7	Mycobacterium_phage	7.4e-21	27.0
WP_063547880.1\|3275801_3277121_+	septum formation initiator	NA	NA	NA	NA
WP_063547882.1\|3277526_3278399_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_069355903.1\|3278519_3279389_+	DMT family transporter	NA	NA	NA	NA
WP_000323764.1\|3279628_3279934_-	monooxygenase	NA	NA	NA	NA
WP_031312939.1\|3280130_3280481_-	DoxX family membrane protein	NA	NA	NA	NA
WP_001048563.1\|3280812_3281232_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000589730.1\|3281707_3282106_-	DUF1259 domain-containing protein	NA	NA	NA	NA
WP_000912131.1\|3282844_3283168_-	hypothetical protein	NA	NA	NA	NA
WP_069355904.1\|3283188_3283659_-	hypothetical protein	NA	NA	NA	NA
WP_001264516.1\|3283930_3284605_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.4e-32	33.9
WP_069355905.1\|3284601_3285975_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.2e-24	29.0
WP_001104104.1\|3286166_3286382_-	hypothetical protein	NA	NA	NA	NA
WP_001064062.1\|3286728_3288174_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_069355906.1\|3288794_3289673_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_069355907.1\|3290032_3291370_+	erythromycin esterase family protein	NA	NA	NA	NA
WP_069355908.1\|3291927_3292680_-\|transposase	transposase	A0A059NT77	Lactococcus_phage	1.7e-55	46.9

DBSCAN-SWA_11

3549048 : 3616153

Macacine_betaherpesvirus(18.18%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069354784.1\|3549048_3549318_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|3549272_3550172_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069356013.1\|3551992_3552706_+	exosporium leader peptide-containing protein	NA	NA	NA	NA
WP_069356014.1\|3552861_3554403_-	alpha-amylase	NA	NA	NA	NA
WP_069356015.1\|3554606_3555398_+	N-hydroxyarylamine O-acetyltransferase	NA	NA	NA	NA
WP_029442916.1\|3555515_3557303_+	oligoendopeptidase F	NA	NA	NA	NA
WP_069356016.1\|3557350_3558397_-	agmatine deiminase family protein	NA	NA	NA	NA
WP_069356017.1\|3558584_3559406_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_069356018.1\|3559448_3560426_-	peptidyl-arginine deiminase	NA	NA	NA	NA
WP_069356019.1\|3560657_3561590_-	hypothetical protein	NA	NA	NA	NA
WP_000916570.1\|3561770_3562187_-	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
WP_016080772.1\|3562355_3563513_-	agmatine deiminase family protein	M1HPT6	Paramecium_bursaria_Chlorella_virus	3.9e-38	29.9
WP_000915203.1\|3563841_3564969_-	serine hydrolase	G1DB24	Mycobacterium_phage	1.5e-18	32.3
WP_069356020.1\|3565328_3565457_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_069356021.1\|3565566_3566796_-	MFS transporter	NA	NA	NA	NA
WP_069356022.1\|3566882_3567734_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_069356023.1\|3567726_3568236_+	DUF3916 domain-containing protein	NA	NA	NA	NA
WP_069356024.1\|3568274_3569219_-	glycerophosphodiester phosphodiesterase	A0A076G4Q2	Staphylococcus_phage	7.0e-38	33.8
WP_069356025.1\|3569586_3570183_-	hypothetical protein	NA	NA	NA	NA
WP_069356026.1\|3570183_3572490_-	AAA family ATPase	NA	NA	NA	NA
WP_069356027.1\|3572541_3573126_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_069356028.1\|3573577_3573841_-	DUF4176 domain-containing protein	NA	NA	NA	NA
WP_069356029.1\|3573837_3574617_-	hypothetical protein	NA	NA	NA	NA
WP_069356030.1\|3574635_3575619_-	type VII secretion protein	NA	NA	NA	NA
WP_069356031.1\|3575615_3576419_-	hypothetical protein	NA	NA	NA	NA
WP_069356032.1\|3576662_3578282_-	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_000571870.1\|3578792_3579137_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000646436.1\|3579155_3580154_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_053563873.1\|3580337_3581804_+	YdiU family protein	A0A075BSJ0	Microcystis_phage	9.2e-45	30.4
WP_069356033.1\|3582059_3583154_+	histidine kinase	A0A2H4J8G3	uncultured_Caudovirales_phage	4.4e-100	51.6
WP_000721431.1\|3583153_3583363_+	hypothetical protein	NA	NA	NA	NA
WP_069356034.1\|3583436_3584036_-	FMN-binding negative transcriptional regulator	NA	NA	NA	NA
WP_053563872.1\|3584728_3585076_-	DUF4260 domain-containing protein	NA	NA	NA	NA
WP_082187992.1\|3585088_3585235_-	transporter	NA	NA	NA	NA
WP_053563871.1\|3585282_3586674_-	FAD-binding protein	NA	NA	NA	NA
WP_000737896.1\|3586800_3587199_-	DUF2871 family protein	NA	NA	NA	NA
WP_053563870.1\|3587452_3587956_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_053563869.1\|3588972_3589542_+	hypothetical protein	NA	NA	NA	NA
WP_053563868.1\|3589951_3591367_+	phosphatidylinositol-specific phospholipase C	NA	NA	NA	NA
WP_001049835.1\|3591538_3592915_-	chitin-binding protein	A0A0K1Y848	Apis_mellifera_filamentous_virus	4.6e-22	36.1
WP_069354782.1\|3593418_3594714_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.5e-11	27.5
WP_069354783.1\|3594703_3595456_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	3.5e-56	46.5
WP_069356035.1\|3596517_3597561_+	cell filamentation protein Fic	NA	NA	NA	NA
WP_000055706.1\|3598415_3599909_+	spore germination protein	NA	NA	NA	NA
WP_000527368.1\|3599910_3601014_+	endospore germination permease	NA	NA	NA	NA
WP_069356036.1\|3601010_3602138_+	Ger(x)C family spore germination protein	NA	NA	NA	NA
WP_069356038.1\|3604601_3605150_-	hypothetical protein	NA	NA	NA	NA
WP_069356039.1\|3605472_3607839_-	DUF3472 domain-containing protein	NA	NA	NA	NA
WP_069354853.1\|3609933_3611079_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.7e-41	28.5
WP_014482097.1\|3612249_3613518_-	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_069356041.1\|3614041_3614260_-	aspartate phosphatase	NA	NA	NA	NA
WP_157452921.1\|3615029_3615929_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|3615883_3616153_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_12

4479588 : 4586577

Klosneuvirus(20.0%)

tRNA,transposase,coat,protease,integrase

attL 4484709:4484732|attR 4570728:4570751

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000903182.1\|4479588_4480356_-\|tRNA	tRNA threonylcarbamoyladenosine dehydratase	NA	NA	NA	NA
WP_000840885.1\|4480656_4482432_-\|tRNA	aspartate--tRNA ligase	A0A1V0SIS0	Klosneuvirus	5.4e-15	33.1
WP_069356224.1\|4482444_4483716_-\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_069356225.1\|4484329_4484662_-	YrdB family protein	NA	NA	NA	NA
4484709:4484732	attL	NA	NA	NA	NA
WP_001266965.1\|4484929_4485370_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_001262795.1\|4485386_4487570_-	GTP diphosphokinase	A0A1B1IUF0	uncultured_Mediterranean_phage	2.4e-12	36.5
WP_000346217.1\|4487780_4488293_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.8e-30	43.8
WP_069356226.1\|4488340_4490680_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	6.6e-85	33.0
WP_069356227.1\|4490781_4491675_-	cation transporter	NA	NA	NA	NA
WP_069356228.1\|4491831_4494096_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	3.3e-33	35.7
WP_000886979.1\|4494365_4494650_-	histidine kinase	NA	NA	NA	NA
WP_000198301.1\|4494835_4496395_+	stage V sporulation protein B	NA	NA	NA	NA
WP_000454821.1\|4496475_4497123_-	DUF421 domain-containing protein	NA	NA	NA	NA
WP_000349148.1\|4497226_4497610_+	TIGR04086 family membrane protein	NA	NA	NA	NA
WP_069356229.1\|4497646_4497907_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	7.4e-06	44.8
WP_000125365.1\|4497934_4499074_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.1e-82	42.3
WP_000354014.1\|4499086_4500139_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_000970410.1\|4500158_4500359_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_000344450.1\|4500355_4501357_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	6.8e-07	26.3
WP_000464511.1\|4501362_4501980_-	Holliday junction DNA helicase RuvA	NA	NA	NA	NA
WP_000823606.1\|4502168_4503113_+	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_069356230.1\|4503124_4503655_-	BofC protein	NA	NA	NA	NA
WP_069356231.1\|4504085_4504520_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_016080194.1\|4504553_4505201_-	spore cortex protein	NA	NA	NA	NA
WP_069356232.1\|4505380_4507315_-\|coat	spore coat assembly protein ExsA	NA	NA	NA	NA
WP_069356233.1\|4507540_4508647_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_069356234.1\|4508677_4509511_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_069356235.1\|4509530_4511060_-	L-aspartate oxidase	NA	NA	NA	NA
WP_069356236.1\|4511212_4512355_+	aminotransferase class V-fold PLP-dependent enzyme	A0A1X7QGF3	Faustovirus	2.1e-28	28.6
WP_053563610.1\|4512354_4512897_+	transcription repressor NadR	NA	NA	NA	NA
WP_053563609.1\|4512976_4513624_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_000621693.1\|4513784_4514636_-	prephenate dehydratase	NA	NA	NA	NA
WP_069356237.1\|4514732_4516646_-	ABC transporter permease	NA	NA	NA	NA
WP_069356238.1\|4516695_4518618_-	ABC transporter permease	NA	NA	NA	NA
WP_000114529.1\|4518592_4519369_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-29	38.4
WP_069356239.1\|4519462_4520545_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_002082113.1\|4520534_4521242_-	response regulator transcription factor	NA	NA	NA	NA
WP_000497127.1\|4521382_4522669_-	GTPase ObgE	NA	NA	NA	NA
WP_001003587.1\|4522668_4523217_-	sporulation protein	NA	NA	NA	NA
WP_000944957.1\|4523280_4523571_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_001993153.1\|4523574_4523919_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_000270907.1\|4523930_4524239_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_069356240.1\|4524408_4525797_-	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_000599064.1\|4525864_4526725_-	stage IV sporulation protein SpoIVFB	NA	NA	NA	NA
WP_000797475.1\|4526717_4527464_-	stage IV sporulation protein SpoIVFA	NA	NA	NA	NA
WP_000503309.1\|4527597_4528395_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_000391521.1\|4528397_4529084_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_000975765.1\|4529119_4529665_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_001135487.1\|4529679_4530531_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_000466736.1\|4530572_4531592_-	rod shape-determining protein MreB	NA	NA	NA	NA
WP_069356241.1\|4532025_4533447_+	hypothetical protein	NA	NA	NA	NA
WP_069356242.1\|4533639_4536447_+	hypothetical protein	NA	NA	NA	NA
WP_061688026.1\|4536476_4538240_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_069356243.1\|4538226_4538979_+	hypothetical protein	NA	NA	NA	NA
WP_080449851.1\|4539519_4539951_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_061688029.1\|4540260_4540536_-	hypothetical protein	NA	NA	NA	NA
WP_069354782.1\|4540988_4542284_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.5e-11	27.5
WP_157452921.1\|4542566_4543466_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|4543420_4543690_-\|transposase	transposase	NA	NA	NA	NA
WP_061688066.1\|4545414_4545912_+	hypothetical protein	NA	NA	NA	NA
WP_061688030.1\|4546305_4546524_-	hypothetical protein	H0USV5	Bacillus_phage	6.8e-21	66.2
WP_000645584.1\|4547998_4548121_-	DUF3983 domain-containing protein	NA	NA	NA	NA
WP_061688031.1\|4548375_4548621_+	hypothetical protein	NA	NA	NA	NA
WP_069356244.1\|4551913_4552255_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_069356245.1\|4552392_4552632_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_069356246.1\|4553284_4555048_-	sulfate permease	A0A2H4J153	uncultured_Caudovirales_phage	6.8e-34	24.2
WP_069356247.1\|4555148_4555580_-	DNA mismatch repair protein	NA	NA	NA	NA
WP_069356248.1\|4555581_4555935_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069356249.1\|4556244_4557012_+	C39 family peptidase	NA	NA	NA	NA
WP_069354786.1\|4558517_4559630_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069356251.1\|4560228_4563303_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	3.4e-41	23.1
WP_084746238.1\|4563623_4564250_-	JAB domain-containing protein	NA	NA	NA	NA
WP_029443367.1\|4564296_4564872_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_069356252.1\|4565105_4566056_-	stage II sporulation protein B	NA	NA	NA	NA
WP_069356253.1\|4566220_4567522_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000072222.1\|4567615_4570261_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.5e-165	43.1
WP_069356254.1\|4570748_4571774_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
4570728:4570751	attR	NA	NA	NA	NA
WP_157452936.1\|4571840_4572851_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_000712942.1\|4572931_4574218_-	glutamate-1-semialdehyde 2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	1.7e-05	34.1
WP_069356256.1\|4574217_4575207_-	porphobilinogen synthase	NA	NA	NA	NA
WP_069356257.1\|4575227_4575980_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_016080168.1\|4575982_4576912_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_000009005.1\|4576927_4577761_-	cytochrome c assembly protein	NA	NA	NA	NA
WP_069356258.1\|4577778_4579113_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_000133921.1\|4579528_4579981_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000359774.1\|4579983_4580400_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_000869118.1\|4580434_4581031_-	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
WP_000097288.1\|4581027_4583358_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	9.5e-177	43.5
WP_000119173.1\|4583540_4585211_-\|protease	ATP-dependent protease LonB	E3T4F6	Cafeteria_roenbergensis_virus	8.7e-15	33.5
WP_000472289.1\|4585317_4586577_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.0e-148	66.3

DBSCAN-SWA_13

4635566 : 4643251

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069356272.1\|4635566_4636490_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.0e-46	44.0
WP_069356273.1\|4636615_4637551_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	3.1e-22	25.0
WP_000018029.1\|4637552_4638245_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.7e-36	38.2
WP_001014310.1\|4638587_4638782_+	YwbE family protein	NA	NA	NA	NA
WP_053563583.1\|4638820_4640020_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.6e-71	41.0
WP_000587818.1\|4640314_4640638_+	heme oxygenase	NA	NA	NA	NA
WP_069356274.1\|4640710_4641475_-	class B sortase	NA	NA	NA	NA
WP_069356275.1\|4641507_4642278_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.6e-14	29.1
WP_001036841.1\|4642267_4643251_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.2e-17	26.9

DBSCAN-SWA_14

5043715 : 5084286

Bacillus_virus(14.29%)

transposase,coat,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000614218.1\|5043715_5044717_-\|coat	spore coat protein CotS	NA	NA	NA	NA
WP_000665102.1\|5044837_5045329_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	4.6e-41	54.5
WP_069356408.1\|5045352_5045832_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_063548939.1\|5045994_5047098_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_069356409.1\|5047042_5048389_+	adenine/guanine phosphoribosyltransferase	NA	NA	NA	NA
WP_000241506.1\|5048394_5049507_+\|protease	cysteine protease StiP family protein	NA	NA	NA	NA
WP_000575380.1\|5049503_5050319_+	HAD hydrolase family protein	NA	NA	NA	NA
WP_069356410.1\|5050875_5051457_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_000276470.1\|5051645_5052410_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_000503347.1\|5052517_5053150_-	transcriptional regulator	NA	NA	NA	NA
WP_000274010.1\|5053230_5053671_-	DUF86 domain-containing protein	NA	NA	NA	NA
WP_000439090.1\|5053818_5054790_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000392613.1\|5054806_5055073_+	DUF3055 domain-containing protein	NA	NA	NA	NA
WP_001174588.1\|5055446_5055944_+	hypothetical protein	NA	NA	NA	NA
WP_000435946.1\|5055989_5056298_-	YutD family protein	NA	NA	NA	NA
WP_000744131.1\|5056416_5056995_+	hypothetical protein	NA	NA	NA	NA
WP_000178777.1\|5057029_5057764_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_069356411.1\|5057864_5058680_+\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_069356412.1\|5058705_5059137_-	hypothetical protein	NA	NA	NA	NA
WP_069356413.1\|5059270_5059825_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_069356414.1\|5059899_5060379_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_000166367.1\|5060399_5061296_-	lipoyl synthase	NA	NA	NA	NA
WP_069356415.1\|5061485_5062469_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_000021807.1\|5062542_5063274_-	sporulation protein YunB	NA	NA	NA	NA
WP_000248467.1\|5063328_5063631_-	DUF1805 domain-containing protein	NA	NA	NA	NA
WP_084746263.1\|5063696_5065088_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_001118824.1\|5065638_5067036_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_000009523.1\|5067084_5067516_-	iron-sulfur cluster assembly scaffold protein SufU	A0A0K1LS29	Mycobacterium_phage	1.5e-14	37.6
WP_069356417.1\|5067505_5068726_-	cysteine desulfurase SufS	Q2XUY6	environmental_halophage	1.8e-118	47.8
WP_000152173.1\|5068725_5070018_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000929163.1\|5070033_5070819_-	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	7.0e-07	26.1
WP_000722397.1\|5071057_5071864_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_053563423.1\|5071937_5072750_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000359401.1\|5072773_5073439_-	ABC transporter permease	NA	NA	NA	NA
WP_000601791.1\|5073431_5074457_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-29	38.1
WP_069356418.1\|5074868_5075213_-	hypothetical protein	NA	NA	NA	NA
WP_000568174.1\|5075365_5075665_-	thioredoxin family protein	NA	NA	NA	NA
WP_000640870.1\|5075677_5076022_-	hypothetical protein	NA	NA	NA	NA
WP_069354853.1\|5076731_5077877_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.7e-41	28.5
WP_000026896.1\|5078079_5078463_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_000218968.1\|5078504_5078870_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.1e-21	48.6
WP_000826910.1\|5079364_5079892_-	hypothetical protein	NA	NA	NA	NA
WP_000713773.1\|5080036_5080684_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000666168.1\|5080749_5081763_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_106823632.1\|5081785_5082985_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_001002981.1\|5082981_5083230_-\|coat	spore coat protein	NA	NA	NA	NA
WP_001180555.1\|5083243_5083429_-	hypothetical protein	NA	NA	NA	NA
WP_069356419.1\|5083572_5084286_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_15

5184459 : 5262386

Bacillus_phage(73.58%)

holin,terminase,transposase,capsid,tail,protease,head,portal,integrase

attL 5175948:5175966|attR 5264664:5264682

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5175948:5175966	attL	NA	NA	NA	NA
WP_069356453.1\|5184459_5184828_-\|holin	CidA/LrgA family holin-like protein	NA	NA	NA	NA
WP_069356454.1\|5185177_5186128_+	nucleoside hydrolase	NA	NA	NA	NA
WP_000103951.1\|5186179_5187475_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.1e-182	75.4
WP_001231158.1\|5187505_5189035_-	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_001231038.1\|5189031_5189787_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_001036331.1\|5189819_5191004_-	phosphoglycerate kinase	NA	NA	NA	NA
WP_000161234.1\|5191143_5192148_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_001258185.1\|5192174_5193203_-	gapA transcriptional regulator CggR	NA	NA	NA	NA
WP_000869726.1\|5193338_5193584_-	glutaredoxin family protein	NA	NA	NA	NA
WP_000647953.1\|5193593_5194901_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_000216166.1\|5195439_5195646_+	DUF1657 domain-containing protein	NA	NA	NA	NA
WP_001228545.1\|5195739_5196225_+	hypothetical protein	NA	NA	NA	NA
WP_000095399.1\|5196254_5196731_+	stage V sporulation protein AC	NA	NA	NA	NA
WP_000938970.1\|5196731_5197748_+	stage V sporulation protein AD	NA	NA	NA	NA
WP_000575919.1\|5197744_5198095_+	stage V sporulation protein AE	NA	NA	NA	NA
WP_000215916.1\|5198106_5198313_+	DUF1657 domain-containing protein	NA	NA	NA	NA
WP_069356455.1\|5198333_5199203_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_001049162.1\|5199443_5200025_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.3e-55	56.5
WP_000250307.1\|5200426_5200675_-	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_000006566.1\|5200698_5201649_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.3e-52	38.4
WP_000712187.1\|5201737_5202691_-	YvcK family protein	A1IMD5	Streptococcus_phage	2.6e-64	43.1
WP_000138459.1\|5202694_5203576_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	4.6e-07	28.9
WP_001190080.1\|5203596_5204055_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_000455196.1\|5204284_5205091_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_069356457.1\|5205423_5206299_+	cytosolic protein	I7ILW0	Bacillus_phage	4.3e-122	81.9
WP_069356458.1\|5206301_5206910_-	hypothetical protein	A0A0S2GLL8	Bacillus_phage	5.3e-103	89.6
WP_069356459.1\|5206899_5208066_-	DNA translocase FtsK	W8CYG2	Bacillus_phage	4.0e-184	81.6
WP_069356460.1\|5208076_5208397_-	hypothetical protein	A0A0S2GLK1	Bacillus_phage	4.5e-37	71.7
WP_157452938.1\|5208414_5208546_-	hypothetical protein	W8CYT8	Bacillus_phage	4.2e-18	90.7
WP_069356461.1\|5208859_5209084_+	helix-turn-helix transcriptional regulator	A0A1B1P883	Bacillus_phage	2.7e-28	79.7
WP_069356462.1\|5210181_5210382_+	hypothetical protein	NA	NA	NA	NA
WP_069356463.1\|5210747_5211938_+	peptidase S8	A0A1B0T6A2	Bacillus_phage	3.5e-167	74.2
WP_069356464.1\|5212509_5212707_+	hypothetical protein	A0A1B0T6A3	Bacillus_phage	3.3e-22	93.7
WP_069356465.1\|5212793_5213546_-	N-acetylmuramoyl-L-alanine amidase	S5M842	Bacillus_phage	1.1e-73	79.3
WP_069356667.1\|5213545_5213752_-	hypothetical protein	D2XR32	Bacillus_phage	3.9e-26	83.3
WP_069356466.1\|5213760_5214042_-	hypothetical protein	D2XR31	Bacillus_phage	2.9e-32	75.8
WP_069356467.1\|5215263_5217690_-	endopeptidase	A0A1B1P770	Bacillus_phage	0.0e+00	81.6
WP_069356468.1\|5217686_5218370_-\|tail	phage tail protein	A0A1C8EA72	Bacillus_phage	6.5e-110	82.7
WP_069356668.1\|5218371_5220777_-\|tail	phage tail tape measure protein	D2XR26	Bacillus_phage	2.5e-111	87.8
WP_069356469.1\|5222407_5222869_-	hypothetical protein	A0A1B1P772	Bacillus_phage	3.6e-64	79.7
WP_069356470.1\|5222940_5223525_-\|tail	phage tail protein	A0A1B1P778	Bacillus_phage	2.2e-90	83.8
WP_084746273.1\|5223525_5223951_-	hypothetical protein	A0A1B1P769	Bacillus_phage	2.7e-61	82.9
WP_069356670.1\|5223937_5224315_-	hypothetical protein	A0A1B1P759	Bacillus_phage	8.4e-59	92.8
WP_069356471.1\|5224331_5224688_-\|head	phage head closure protein	A0A1B1P760	Bacillus_phage	1.1e-47	78.8
WP_069356472.1\|5224668_5224965_-	hypothetical protein	A0A1B1P751	Bacillus_phage	6.2e-41	86.7
WP_069356473.1\|5224969_5225431_-	hypothetical protein	X2KQD1	Enterococcus_phage	8.5e-13	37.2
WP_069356474.1\|5225518_5226676_-\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	1.4e-83	43.0
WP_069356475.1\|5226716_5227430_-\|protease	Clp protease ClpP	A0A2H4JC91	uncultured_Caudovirales_phage	1.5e-56	53.7
WP_069356476.1\|5227416_5228583_-\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	7.3e-186	82.6
WP_084746419.1\|5228594_5230211_-\|terminase	terminase large subunit	A0A1B1P766	Bacillus_phage	3.3e-237	71.7
WP_069356477.1\|5230242_5230764_-	RNA polymerase subunit sigma-70	E2ELI1	Clostridium_phage	3.1e-27	46.2
WP_069356672.1\|5230952_5231261_-	hypothetical protein	A0A1B1P767	Bacillus_phage	1.6e-39	82.7
WP_069356479.1\|5231263_5231611_-	HNH endonuclease	A0A1B1P757	Bacillus_phage	3.6e-24	51.3
WP_157452939.1\|5232086_5233100_-	DUF2974 domain-containing protein	NA	NA	NA	NA
WP_069354777.1\|5233877_5235173_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-09	27.1
WP_069354776.1\|5235162_5235915_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	7.8e-56	46.9
WP_069356481.1\|5236279_5236822_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1P746	Bacillus_phage	2.1e-95	98.9
WP_069356482.1\|5236818_5237289_-	ArpU family transcriptional regulator	A0A1B1P744	Bacillus_phage	8.3e-48	61.2
WP_157452940.1\|5237585_5237717_-	DUF3983 domain-containing protein	A0A1B0T6D3	Bacillus_phage	6.5e-11	88.4
WP_069356484.1\|5238341_5239139_-	phage antirepressor KilAC domain-containing protein	A0A1Q1PVZ8	Staphylococcus_phage	3.3e-73	52.5
WP_069356485.1\|5239352_5239751_-	hypothetical protein	A0A1B0T6B6	Bacillus_phage	8.8e-67	96.2
WP_069356486.1\|5239785_5239953_-	DUF3954 domain-containing protein	A0A0S2GLF5	Bacillus_phage	6.0e-17	77.8
WP_069356487.1\|5240025_5240292_-	hypothetical protein	A0A0S2GLK4	Bacillus_phage	9.8e-38	89.8
WP_069356488.1\|5240288_5240573_-	hypothetical protein	A0A1B1P7W1	Bacillus_phage	3.5e-17	50.5
WP_069356489.1\|5240545_5241451_-	ATP-binding protein	A0A1B0T6C3	Bacillus_phage	9.9e-90	62.1
WP_069356490.1\|5241401_5242250_-	replication protein	A0A0H4IPD8	Staphylococcus_phage	2.4e-21	58.6
WP_069356492.1\|5242684_5243005_-	hypothetical protein	A0A0S2GLB6	Bacillus_phage	2.9e-28	67.3
WP_023523419.1\|5243511_5243700_-	helix-turn-helix transcriptional regulator	W8CYN7	Bacillus_phage	5.7e-24	90.3
WP_023523420.1\|5243778_5243982_-	helix-turn-helix transcriptional regulator	A0A0A7AQV9	Bacillus_phage	4.0e-15	59.1
WP_023523421.1\|5244142_5244502_+	helix-turn-helix transcriptional regulator	H0UST7	Bacillus_phage	3.3e-12	38.5
WP_157452941.1\|5244831_5244978_-	hypothetical protein	NA	NA	NA	NA
WP_069356673.1\|5245017_5246178_-	helix-turn-helix transcriptional regulator	A0A0A7AQH4	Bacillus_phage	1.9e-125	60.7
WP_069356493.1\|5246845_5247907_+\|integrase	site-specific integrase	A0A0S2GLI2	Bacillus_phage	3.2e-164	82.7
WP_001288078.1\|5248144_5249101_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.4e-89	53.6
WP_000517723.1\|5249186_5250698_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_069356494.1\|5250836_5251349_-	acetyltransferase	NA	NA	NA	NA
WP_069356495.1\|5251382_5252033_-	pyrophosphatase PpaX	NA	NA	NA	NA
WP_069356496.1\|5252100_5252913_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_001127251.1\|5252937_5253867_-	HPr(Ser) kinase/phosphatase	NA	NA	NA	NA
WP_001267308.1\|5254023_5254404_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_069356497.1\|5254592_5257469_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	57.2
WP_016118880.1\|5257474_5259451_-	excinuclease ABC subunit B	NA	NA	NA	NA
WP_069356498.1\|5259601_5260033_-	DUF4362 domain-containing protein	NA	NA	NA	NA
WP_053563372.1\|5260078_5260699_-	hypothetical protein	NA	NA	NA	NA
WP_069354786.1\|5261273_5262386_-\|transposase	IS110 family transposase	NA	NA	NA	NA
5264664:5264682	attR	NA	NA	NA	NA

DBSCAN-SWA_16

5555104 : 5608907

Streptococcus_phage(11.76%)

holin,tRNA,transposase,protease,integrase

attL 5604315:5604330|attR 5609024:5609039

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000168869.1\|5555104_5555797_-\|holin	antiholin-like protein LrgB	NA	NA	NA	NA
WP_053563271.1\|5555832_5556264_-\|holin	antiholin-like murein hydrolase modulator LrgA	NA	NA	NA	NA
WP_000921848.1\|5556396_5557137_-	response regulator transcription factor	NA	NA	NA	NA
WP_069354786.1\|5557728_5558841_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069356586.1\|5560787_5562086_+	MFS transporter	NA	NA	NA	NA
WP_001242450.1\|5562138_5563707_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.3e-15	23.9
WP_000047620.1\|5564067_5565138_-	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_000094037.1\|5565355_5565982_+	superoxide dismutase [Mn]	Q56AR7	Bacillus_thuringiensis_phage	2.6e-57	53.2
WP_100910525.1\|5566070_5566964_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_000540540.1\|5567060_5567651_-	acetamide transporter	NA	NA	NA	NA
WP_069356587.1\|5568022_5568424_+	hypothetical protein	NA	NA	NA	NA
WP_053563268.1\|5568979_5569996_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	3.6e-96	51.6
WP_069356588.1\|5570181_5570829_-	hemolysin III family protein	NA	NA	NA	NA
WP_069356589.1\|5570993_5571554_+	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_069356590.1\|5571702_5572941_-	hypothetical protein	NA	NA	NA	NA
WP_069356591.1\|5573184_5574630_-	ATP-dependent RNA helicase DbpA	A0A1V0SBR7	Catovirus	1.3e-59	34.4
WP_069356592.1\|5575104_5576088_+	GMP reductase	G3MBI2	Bacillus_virus	1.7e-159	84.4
WP_069356593.1\|5576225_5578043_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	2.6e-121	38.7
WP_069356594.1\|5578080_5578959_-	radical SAM protein	NA	NA	NA	NA
WP_069356595.1\|5579180_5581199_-	GAF domain-containing protein	NA	NA	NA	NA
WP_069356596.1\|5581278_5581779_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_001052833.1\|5581838_5582024_-	CxxH/CxxC protein	NA	NA	NA	NA
WP_000008031.1\|5582077_5583253_-\|protease	serine protease	W5SAB9	Pithovirus	1.0e-09	31.9
WP_000522837.1\|5583316_5584111_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	6.1e-43	35.3
WP_000383720.1\|5584094_5584937_-	hypothetical protein	NA	NA	NA	NA
WP_069356597.1\|5584917_5586234_-	hypothetical protein	NA	NA	NA	NA
WP_000755367.1\|5586230_5588072_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	8.9e-37	35.0
WP_000971865.1\|5588075_5588783_-	cell wall metabolism DNA-binding response regulator WalR	W8CYM9	Bacillus_phage	7.6e-45	42.7
WP_000100230.1\|5589576_5590866_-	adenylosuccinate synthase	L7Y4J5	Megavirus	9.5e-70	36.2
WP_001286147.1\|5591081_5592431_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	2.5e-121	52.3
WP_000864223.1\|5592458_5592905_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_001113779.1\|5592901_5594875_-	DHH family phosphoesterase	NA	NA	NA	NA
WP_053563260.1\|5594953_5595889_-	YybS family protein	NA	NA	NA	NA
WP_000918873.1\|5595969_5596203_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_002094213.1\|5596248_5596770_-	single-stranded DNA-binding protein	A0A290GHL8	Caldibacillus_phage	4.0e-51	61.8
WP_001233781.1\|5596796_5597087_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_069356598.1\|5597278_5598379_-	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_000435486.1\|5598494_5598692_-	DUF951 domain-containing protein	NA	NA	NA	NA
WP_000365111.1\|5598712_5599594_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_053563259.1\|5599853_5600450_+\|protease	spore protease YyaC	A0A0A8WIQ6	Clostridium_phage	1.1e-23	38.8
WP_053563258.1\|5600470_5601328_-	stage 0 sporulation protein Spo0J	I3NLC2	Bifidobacterium_phage	2.5e-18	34.4
WP_113303242.1\|5601314_5602103_-	sporulation initiation inhibitor protein Soj	Q8JL10	Natrialba_phage	6.3e-24	29.7
WP_000799016.1\|5602266_5603139_-	nucleoid occlusion protein	S5VTK0	Leptospira_phage	9.1e-16	36.4
WP_001019628.1\|5603244_5603964_-	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_069356599.1\|5603986_5605876_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
5604315:5604330	attL	NA	NA	NA	NA
WP_000393762.1\|5605922_5607299_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_000022795.1\|5607525_5608143_-	protein jag	NA	NA	NA	NA
WP_000727740.1\|5608139_5608907_-\|integrase	YidC family membrane integrase SpoIIIJ	NA	NA	NA	NA
5609024:5609039	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP015252

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

168 : 85796

Macacine_betaherpesvirus(16.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069356772.1\|168_363_-\|transposase	transposase	NA	NA	NA	NA
WP_069356684.1\|492_1098_-	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	2.4e-15	32.0
WP_157452921.1\|1490_2390_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|2344_2614_-\|transposase	transposase	NA	NA	NA	NA
WP_157452953.1\|3272_3554_-	hypothetical protein	NA	NA	NA	NA
WP_069354782.1\|4025_5321_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	2.2e-42	31.8
WP_069354783.1\|5310_6063_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	3.5e-56	46.5
WP_069356777.1\|7346_7730_-	hypothetical protein	NA	NA	NA	NA
WP_069356778.1\|7877_9635_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_069356779.1\|9631_11026_-	isochorismate synthase	NA	NA	NA	NA
WP_069356780.1\|11190_11877_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	7.1e-72	59.4
WP_069356823.1\|12679_12967_+	adhesin	NA	NA	NA	NA
WP_084746135.1\|13490_14363_-	recombinase family protein	A0A219Y9V9	Aeromonas_phage	2.5e-37	48.6
WP_084746451.1\|14521_17515_+\|transposase	Tn3 family transposase	A0A125RQ78	Bacillus_phage	0.0e+00	55.5
WP_069356678.1\|18859_19435_-	recombinase family protein	A0A1V0E035	Clostridioides_phage	1.6e-24	35.6
WP_069356783.1\|19786_20935_+	HBL/NHE enterotoxin family protein	NA	NA	NA	NA
WP_069356784.1\|20979_22170_+	HBL/NHE enterotoxin family protein	NA	NA	NA	NA
WP_069356785.1\|22252_23155_+	HBL/NHE enterotoxin family protein	NA	NA	NA	NA
WP_069356786.1\|23239_24088_+	hypothetical protein	NA	NA	NA	NA
WP_069356788.1\|26343_27285_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_069356789.1\|27649_28006_-	hypothetical protein	NA	NA	NA	NA
WP_001032326.1\|28154_28382_-	hypothetical protein	NA	NA	NA	NA
WP_069356824.1\|28812_29616_+	ADP ribosyltransferase	Q331X8	Clostridium_botulinum_C_phage	2.4e-15	28.7
WP_069356791.1\|31010_32201_-	C1 family peptidase	A0A2K9L9R4	Tupanvirus	9.6e-16	26.7
WP_157452954.1\|32571_33888_+	hypothetical protein	NA	NA	NA	NA
WP_069356780.1\|33902_34589_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	7.1e-72	59.4
WP_069356793.1\|35140_36058_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_069356794.1\|36384_36966_+	recombinase family protein	A0A219Y9V9	Aeromonas_phage	2.8e-29	39.7
WP_069356795.1\|36986_37421_-	hypothetical protein	NA	NA	NA	NA
WP_069356796.1\|38348_39164_+	5'-nucleotidase, lipoprotein e(P4) family	NA	NA	NA	NA
WP_030029980.1\|40334_40520_-	hypothetical protein	NA	NA	NA	NA
WP_069356797.1\|41140_42925_+	acetyltransferase	B5WZU0	Pseudomonas_phage	2.4e-39	31.1
WP_069356798.1\|43058_43739_+	autotransporter	NA	NA	NA	NA
WP_069356799.1\|43759_44032_+	hypothetical protein	NA	NA	NA	NA
WP_069356800.1\|44367_44844_-	hypothetical protein	NA	NA	NA	NA
WP_069356801.1\|48060_48291_+	hypothetical protein	NA	NA	NA	NA
WP_069356803.1\|48815_49928_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_157452955.1\|51503_51677_+	hypothetical protein	NA	NA	NA	NA
WP_157452921.1\|51709_52609_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|52563_52833_-\|transposase	transposase	NA	NA	NA	NA
WP_069356804.1\|57754_60169_-	conjugal transfer protein TraE	G3MBM1	Bacillus_virus	3.0e-08	23.2
WP_069356805.1\|60505_60850_-	hypothetical protein	NA	NA	NA	NA
WP_069356806.1\|60850_61681_-	hypothetical protein	NA	NA	NA	NA
WP_084746453.1\|61746_62232_-	hypothetical protein	NA	NA	NA	NA
WP_069356808.1\|62702_63173_-	hypothetical protein	NA	NA	NA	NA
WP_016110563.1\|63403_63619_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069356809.1\|63819_64317_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069356810.1\|64650_65595_+	Replicase RepFR55	NA	NA	NA	NA
WP_016110568.1\|67020_68211_+	ParM/StbA family protein	NA	NA	NA	NA
WP_069356811.1\|68217_68601_+	hypothetical protein	NA	NA	NA	NA
WP_157452956.1\|68917_69055_-	Phr family secreted Rap phosphatase inhibitor	NA	NA	NA	NA
WP_069356812.1\|69056_70151_-	tetratricopeptide repeat protein	A0A2H4J8G3	uncultured_Caudovirales_phage	4.9e-83	46.9
WP_157452921.1\|70694_71594_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|71548_71818_-\|transposase	transposase	NA	NA	NA	NA
WP_069356813.1\|72305_73502_-	DUF3801 domain-containing protein	NA	NA	NA	NA
WP_061685793.1\|73765_74476_+	hypothetical protein	NA	NA	NA	NA
WP_069356814.1\|74492_75812_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_069356815.1\|75898_76099_+	hypothetical protein	NA	NA	NA	NA
WP_157452957.1\|76236_76395_+	hypothetical protein	NA	NA	NA	NA
WP_069354782.1\|76477_77773_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	2.2e-42	31.8
WP_069354783.1\|77762_78515_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	3.5e-56	46.5
WP_000156990.1\|78724_78910_+	hypothetical protein	NA	NA	NA	NA
WP_069356816.1\|79011_80193_+	cell division protein FtsK	H0USY1	Bacillus_phage	7.8e-127	55.3
WP_069356817.1\|80131_80749_+	hypothetical protein	Q2LIA9	Bacillus_phage	6.9e-34	45.1
WP_069356818.1\|80758_80989_-	helix-turn-helix transcriptional regulator	A0A0S2MVM0	Bacillus_phage	1.7e-17	54.5
WP_069356819.1\|81847_82069_-	hypothetical protein	NA	NA	NA	NA
WP_084746457.1\|82479_82674_-	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_157452958.1\|82708_83320_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.0e-50	49.5
WP_069356772.1\|83574_83769_-\|transposase	transposase	NA	NA	NA	NA
WP_069356684.1\|83898_84504_-	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	2.4e-15	32.0
WP_157452921.1\|84896_85796_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP015253

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

20494 : 66375

Bacillus_phage(50.0%)

integrase,transposase

attL 20378:20437|attR 38629:40214

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
20378:20437	attL	NA	NA	NA	NA
WP_069354786.1\|20494_21607_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069356840.1\|24091_25390_+	hypothetical protein	NA	NA	NA	NA
WP_084746464.1\|25423_26209_+	hypothetical protein	NA	NA	NA	NA
WP_069356841.1\|26319_26766_+	hypothetical protein	NA	NA	NA	NA
WP_069356842.1\|26909_27344_-	hypothetical protein	NA	NA	NA	NA
WP_069356843.1\|27792_28491_-	hypothetical protein	A0A1B1P7T2	Bacillus_phage	7.2e-48	44.7
WP_069356844.1\|28496_29678_-	DNA translocase FtsK	A0A1B1P7T5	Bacillus_phage	2.8e-68	39.4
WP_069356845.1\|29999_30473_+	DUF559 domain-containing protein	NA	NA	NA	NA
WP_069356846.1\|30869_31160_-	hypothetical protein	NA	NA	NA	NA
WP_069356847.1\|31603_31891_-	hypothetical protein	NA	NA	NA	NA
WP_069356848.1\|31966_32197_-	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_029437091.1\|32246_32474_-	hypothetical protein	NA	NA	NA	NA
WP_157452962.1\|32517_32715_-	hypothetical protein	NA	NA	NA	NA
WP_069356850.1\|32837_33041_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_069356851.1\|33180_33753_-\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	7.0e-33	42.4
WP_069354783.1\|34196_34949_-	AAA family ATPase	A0A059NT77	Lactococcus_phage	3.5e-56	46.5
WP_069354782.1\|34938_36234_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	2.2e-42	31.8
WP_069356852.1\|36659_37070_+	hypothetical protein	NA	NA	NA	NA
WP_069354786.1\|37458_38571_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069356853.1\|38689_39199_-	DUF4367 domain-containing protein	NA	NA	NA	NA
WP_084746043.1\|39472_40726_+\|transposase	transposase	NA	NA	NA	NA
38629:40214	attR	NA	NA	NA	NA
WP_157452921.1\|41469_42369_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|42323_42593_-\|transposase	transposase	NA	NA	NA	NA
WP_069356890.1\|42719_43034_+	XRE family transcriptional regulator	NA	NA	NA	NA
WP_002187663.1\|43087_43276_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_069354786.1\|43795_44908_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069356854.1\|45322_45547_+	hypothetical protein	NA	NA	NA	NA
WP_069356855.1\|45543_46227_+	hypothetical protein	NA	NA	NA	NA
WP_069356856.1\|46800_47196_+	hypothetical protein	NA	NA	NA	NA
WP_069356857.1\|47211_47595_+	hypothetical protein	NA	NA	NA	NA
WP_069356858.1\|47773_48343_-	recombinase family protein	A0A219Y9V9	Aeromonas_phage	4.3e-30	40.1
WP_069356754.1\|48584_49967_+	MmcB family DNA repair protein	NA	NA	NA	NA
WP_069356771.1\|50076_50472_-	hypothetical protein	NA	NA	NA	NA
WP_069356755.1\|50573_53546_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.6e-75	25.5
WP_084746466.1\|53693_54212_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_069356760.1\|54383_55421_+	hypothetical protein	NA	NA	NA	NA
WP_157452951.1\|55702_56471_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_069356763.1\|56932_57910_+	hypothetical protein	NA	NA	NA	NA
WP_069356764.1\|58451_59639_+	pesticidal crystal protein Cry6Ba	O64021	Bacillus_phage	1.4e-46	34.3
WP_069356676.1\|61403_62294_-	hypothetical protein	NA	NA	NA	NA
WP_084746474.1\|63381_66375_-\|transposase	Tn3 family transposase	A0A125RQ78	Bacillus_phage	0.0e+00	55.4

DBSCAN-SWA_2

86348 : 92837

Bacillus_phage(66.67%)

transposase,integrase

attL 84053:84068|attR 95680:95695

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
84053:84068	attL	NA	NA	NA	NA
WP_069356860.1\|86348_87134_+\|integrase	tyrosine-type recombinase/integrase	S5M9V8	Brevibacillus_phage	1.0e-26	31.6
WP_069356872.1\|87185_90203_-\|transposase	Tn3 family transposase	A0A125RQ78	Bacillus_phage	0.0e+00	99.1
WP_069356873.1\|90274_91195_-\|integrase	tyrosine-type recombinase/integrase	A0A0A7AR08	Bacillus_phage	9.9e-170	99.0
WP_001007679.1\|91350_91608_+	hypothetical protein	A0A125RQ77	Bacillus_phage	9.5e-38	90.6
WP_002163075.1\|91576_91840_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A125RQ76	Bacillus_phage	2.2e-42	96.6
WP_069356874.1\|92213_92837_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	3.7e-11	28.8
95680:95695	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP015254

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2696 : 63164

Streptococcus_phage(21.05%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069355686.1\|2696_3809_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000348470.1\|5107_5338_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001106069.1\|5534_6071_+	helix-turn-helix transcriptional regulator	A0A0S2SXM8	Bacillus_phage	4.0e-06	37.4
WP_069356896.1\|6397_7597_+	hypothetical protein	NA	NA	NA	NA
WP_157452921.1\|9954_10854_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|10808_11078_-\|transposase	transposase	NA	NA	NA	NA
WP_000846305.1\|11368_12565_+	ParM/StbA family protein	NA	NA	NA	NA
WP_000532774.1\|12578_12998_+	hypothetical protein	NA	NA	NA	NA
WP_000271589.1\|13044_13320_+	hypothetical protein	D2XQ08	Bacillus_virus	2.2e-16	56.5
WP_069356897.1\|13724_14021_-	hypothetical protein	NA	NA	NA	NA
WP_000066815.1\|14067_14397_-	hypothetical protein	NA	NA	NA	NA
WP_000680007.1\|14435_14696_-	hypothetical protein	NA	NA	NA	NA
WP_069356898.1\|14954_17804_+	Mobilization protein	NA	NA	NA	NA
WP_069356899.1\|17813_18476_+	hypothetical protein	NA	NA	NA	NA
WP_000532062.1\|18608_18905_+	hypothetical protein	H0USY0	Bacillus_phage	5.8e-15	43.7
WP_000156991.1\|18906_19092_+	hypothetical protein	NA	NA	NA	NA
WP_069356827.1\|20523_22329_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.0e-29	27.2
WP_069356900.1\|22919_23537_+	hypothetical protein	Q2LIA9	Bacillus_phage	6.0e-38	46.6
WP_000468340.1\|23541_23778_-	helix-turn-helix transcriptional regulator	S5MBY6	Brevibacillus_phage	4.8e-12	41.1
WP_069355414.1\|24391_25537_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.3e-41	28.5
WP_157452963.1\|26210_26456_-	hypothetical protein	NA	NA	NA	NA
WP_069356720.1\|26474_27182_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	9.3e-43	42.5
WP_069356684.1\|27526_28132_+	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	2.4e-15	32.0
WP_084746135.1\|28841_29714_-	recombinase family protein	A0A219Y9V9	Aeromonas_phage	2.5e-37	48.6
WP_069356720.1\|30166_30874_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	9.3e-43	42.5
WP_069354776.1\|31052_31805_-	AAA family ATPase	A0A059NT77	Lactococcus_phage	7.8e-56	46.9
WP_069354777.1\|31794_33090_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.7e-42	31.0
WP_069356903.1\|33922_34864_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_100248682.1\|35299_35524_-	hypothetical protein	NA	NA	NA	NA
WP_069354784.1\|35675_35945_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|35899_36799_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_084746481.1\|36899_37241_-	hypothetical protein	NA	NA	NA	NA
WP_069356720.1\|37705_38413_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	9.3e-43	42.5
WP_069356906.1\|38478_38667_-	hypothetical protein	NA	NA	NA	NA
WP_069356907.1\|39068_39398_+	hypothetical protein	NA	NA	NA	NA
WP_000136353.1\|39588_40131_-	hypothetical protein	NA	NA	NA	NA
WP_069355686.1\|41706_42819_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_061656737.1\|43343_43574_-	hypothetical protein	NA	NA	NA	NA
WP_069356930.1\|44156_44675_+	hypothetical protein	NA	NA	NA	NA
WP_069356931.1\|44902_46048_-	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_069356908.1\|47227_48649_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_157452964.1\|48713_49913_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_069356910.1\|49954_51013_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_084746483.1\|51242_52841_+	hypothetical protein	NA	NA	NA	NA
WP_069356911.1\|53372_53816_-	hypothetical protein	NA	NA	NA	NA
WP_084746485.1\|54400_54814_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_065486709.1\|55053_55371_-	hypothetical protein	A0A2H4JAV2	uncultured_Caudovirales_phage	7.4e-16	42.1
WP_069356913.1\|55617_55824_+	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_069356915.1\|57672_58311_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.7e-09	25.4
WP_069356916.1\|58300_58849_-	hypothetical protein	NA	NA	NA	NA
WP_069356917.1\|58862_59372_-	stage II sporulation protein M	NA	NA	NA	NA
WP_069356918.1\|59376_61083_-	hypothetical protein	NA	NA	NA	NA
WP_016106960.1\|61164_61488_-\|bacteriocin	circular bacteriocin, circularin A/uberolysin family	NA	NA	NA	NA
WP_069356919.1\|62456_63164_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.7e-42	42.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP015251

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

467 : 87861

Macacine_betaherpesvirus(34.62%)

integrase,protease,transposase

attL 3473:3532|attR 16635:17861

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157452921.1\|467_1367_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|1321_1591_-\|transposase	transposase	NA	NA	NA	NA
WP_069356676.1\|2469_3360_+	hypothetical protein	NA	NA	NA	NA
3473:3532	attL	NA	NA	NA	NA
WP_069354784.1\|3540_3810_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|3764_4664_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069356678.1\|5286_5862_-	recombinase family protein	A0A1V0E035	Clostridioides_phage	1.6e-24	35.6
WP_157452946.1\|6034_6208_-	hypothetical protein	NA	NA	NA	NA
WP_157452921.1\|7185_8085_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|8039_8309_-\|transposase	transposase	NA	NA	NA	NA
WP_157452947.1\|8349_8523_+	hypothetical protein	S6AND0	Bacillus_phage	1.9e-05	74.2
WP_069356679.1\|8495_9497_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_069356680.1\|9900_11073_+\|integrase	site-specific integrase	A0A142F1N9	Bacillus_phage	1.2e-05	25.0
WP_069356683.1\|12540_13467_+\|integrase	site-specific integrase	A0A1B1P793	Bacillus_phage	2.3e-65	44.3
WP_157452921.1\|15502_16402_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|16356_16626_-\|transposase	transposase	NA	NA	NA	NA
WP_069356684.1\|18634_19240_+	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	2.4e-15	32.0
16635:17861	attR	NA	NA	NA	NA
WP_069356685.1\|22283_22856_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_157452921.1\|23289_24189_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|24143_24413_-\|transposase	transposase	NA	NA	NA	NA
WP_069356686.1\|24661_25573_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	8.7e-09	31.4
WP_069356687.1\|25554_26664_-	polysaccharide pyruvyl transferase family protein	A0A2H4UTU3	Bodo_saltans_virus	7.1e-05	25.4
WP_069356688.1\|28877_29240_+	hypothetical protein	NA	NA	NA	NA
WP_069356689.1\|29309_29657_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069356690.1\|31201_32200_+	glycosyltransferase family 1 protein	L7RD44	Acanthamoeba_polyphaga_moumouvirus	1.0e-10	41.6
WP_069356691.1\|32162_33260_+	polysaccharide pyruvyl transferase family protein	NA	NA	NA	NA
WP_069354784.1\|36167_36437_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|36391_37291_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_084746426.1\|38131_38515_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_069356693.1\|38891_39482_+	DUF3967 domain-containing protein	A0A1Z1LZN4	Bacillus_phage	1.2e-08	31.6
WP_069354784.1\|41898_42168_+\|transposase	transposase	NA	NA	NA	NA
WP_157452921.1\|42122_43022_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069356695.1\|43167_44244_-	CDP-glucose 4,6-dehydratase	J7Q7J8	Aeropyrum_coil-shaped_virus	3.1e-13	37.9
WP_069356696.1\|44259_45228_-	SDR family NAD(P)-dependent oxidoreductase	A0A1V0SKV4	Klosneuvirus	7.3e-22	29.2
WP_069356697.1\|45260_47375_-	glycosyl transferase	NA	NA	NA	NA
WP_069356698.1\|47394_48135_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_069356699.1\|50225_50726_-	hypothetical protein	NA	NA	NA	NA
WP_069356700.1\|50752_51247_-	hypothetical protein	NA	NA	NA	NA
WP_157452948.1\|52698_52944_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_069354782.1\|54159_55455_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	2.2e-42	31.8
WP_069356704.1\|56099_56525_+	hypothetical protein	NA	NA	NA	NA
WP_084746428.1\|59040_60639_+	hypothetical protein	NA	NA	NA	NA
WP_069356707.1\|61166_61610_-	hypothetical protein	NA	NA	NA	NA
WP_127814282.1\|62185_62236_-	hypothetical protein	NA	NA	NA	NA
WP_065486709.1\|62880_63198_-	hypothetical protein	A0A2H4JAV2	uncultured_Caudovirales_phage	7.4e-16	42.1
WP_069356708.1\|63992_64184_+	hypothetical protein	NA	NA	NA	NA
WP_069356709.1\|64410_64746_-\|protease	protease inhibitor I42 family protein	NA	NA	NA	NA
WP_078185372.1\|66664_67252_-	methyltransferase	NA	NA	NA	NA
WP_069356711.1\|67688_68114_-	hypothetical protein	NA	NA	NA	NA
WP_084746430.1\|68372_71093_-	collagenase	NA	NA	NA	NA
WP_069356712.1\|71868_72144_-	hypothetical protein	H0USV6	Bacillus_phage	2.4e-15	49.5
WP_069356769.1\|73605_74103_+	hypothetical protein	NA	NA	NA	NA
WP_069356713.1\|74494_74713_-	hypothetical protein	H0USV5	Bacillus_phage	2.0e-20	64.9
WP_157452921.1\|75292_76192_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|76146_76416_-\|transposase	transposase	NA	NA	NA	NA
WP_069356716.1\|78455_78680_+	hypothetical protein	H0USX6	Bacillus_phage	2.9e-19	77.8
WP_157452921.1\|81503_82403_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.5e-24	37.3
WP_069354784.1\|82357_82627_-\|transposase	transposase	NA	NA	NA	NA
WP_069354786.1\|85479_86592_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_069356720.1\|87153_87861_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	9.3e-43	42.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage