CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP012491	Escherichia coli strain CFSAN004176 plasmid pCFSAN004176P_03, complete sequence	0 crisprs	NA	0	1
NZ_CP012492	Escherichia coli strain CFSAN004176 plasmid pCFSAN004176P_01, complete sequence	0 crisprs	NA	0	1
NZ_CP012493	Escherichia coli strain CFSAN004176 plasmid pCFSAN004176G_02, complete sequence	0 crisprs	NA	0	1
NZ_CP014583	Escherichia coli strain CFSAN004176 chromosome, complete genome	8 crisprs	c2c9_V-U4,DEDDh,DinG,cas3,csa3,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	3	17

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 95101

112

Escherichia_phage(61.11%)

portal,tail,head,holin,integrase

attL 31865:31881|attR 82927:82943

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024183070.1\|459_936_+\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	1.2e-46	58.2
WP_001408994.1\|946_1408_+\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	2.0e-54	69.6
WP_023154361.1\|1418_1886_+\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	1.4e-50	65.8
WP_023156927.1\|1896_2325_+\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	1.3e-39	54.9
WP_064754908.1\|2353_2839_+\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	2.0e-41	53.6
WP_042004948.1\|2867_3278_+\|tail	tail fiber protein	K7PH60	Enterobacterial_phage	1.9e-48	70.4
WP_071852594.1\|3306_3786_+\|tail	tail fiber protein	K7P7Q7	Enterobacteria_phage	3.2e-39	54.4
WP_000367945.1\|3791_4403_-\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	3.6e-83	78.6
WP_077886821.1\|4402_6982_-\|tail	tail fiber protein	A0A1B0V7G4	Salmonella_phage	8.7e-14	45.5
WP_001286325.1\|6993_7428_-	hypothetical protein	A0A077SLL3	Escherichia_phage	7.4e-75	99.3
WP_001189832.1\|7506_8343_-	hypothetical protein	A0A1B0V7F2	Salmonella_phage	1.4e-154	100.0
WP_000047923.1\|8342_9776_-	bleomycin hydrolase	A0A1B0VAD6	Salmonella_phage	3.7e-272	100.0
WP_000002800.1\|9772_10129_-	hypothetical protein	Q71TP1	Escherichia_phage	1.0e-61	100.0
WP_023351689.1\|10128_13503_-	transglycosylase SLT domain-containing protein	Q1MVL3	Enterobacteria_phage	0.0e+00	85.9
WP_000926345.1\|13584_14466_-	hypothetical protein	A0A1B0VBL3	Salmonella_phage	3.7e-174	99.7
WP_000523975.1\|14480_15092_-	hypothetical protein	Q71TN8	Escherichia_phage	2.7e-107	98.0
WP_000188920.1\|15102_15669_-	hypothetical protein	A0A077SK12	Escherichia_phage	6.6e-100	99.5
WP_024174696.1\|15823_16993_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_000780957.1\|16994_17501_-	hypothetical protein	NA	NA	NA	NA
WP_032346387.1\|17589_18108_-	hypothetical protein	Q71TC4	Escherichia_phage	3.1e-19	92.2
WP_000245708.1\|18508_18730_+	host cell division inhibitor Icd-like protein	A0A077SLM6	Escherichia_phage	2.8e-38	98.6
WP_000743162.1\|18726_19770_+	phage antirepressor Ant	Q71TN2	Escherichia_phage	3.6e-176	94.8
WP_001187871.1\|19934_20735_+	phage antirepressor KilAC domain-containing protein	Q1MVK4	Enterobacteria_phage	5.4e-148	99.6
WP_023154394.1\|20764_21610_+	hypothetical protein	Q1MVK3	Enterobacteria_phage	3.8e-152	99.3
WP_059339312.1\|21660_21906_+	hypothetical protein	A0A1B0VDM5	Salmonella_phage	3.5e-13	46.2
WP_001313475.1\|22087_22243_+	type I toxin-antitoxin system toxin HokD	A0A1I9LJU7	Stx_converting_phage	1.0e-15	92.2
WP_000509939.1\|22359_22869_-	hypothetical protein	Q1MVJ9	Enterobacteria_phage	1.3e-91	100.0
WP_000035301.1\|22880_23462_-	hypothetical protein	Q1MVJ8	Enterobacteria_phage	7.3e-102	97.4
WP_046659860.1\|23497_24313_-	hypothetical protein	A0A1B0V835	Salmonella_phage	6.8e-114	100.0
WP_000085143.1\|24322_25912_-	hypothetical protein	Q71TB2	Escherichia_phage	1.1e-306	100.0
WP_000067710.1\|25972_27679_-	hypothetical protein	Q71TM1	Escherichia_phage	0.0e+00	100.0
WP_000038866.1\|27904_28906_-	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	1.7e-178	100.0
WP_001285362.1\|28922_30119_-	AAA family ATPase	A0A077SL49	Escherichia_phage	1.6e-225	100.0
WP_001076427.1\|30676_31537_-	replication protein RepA	Q71TL8	Escherichia_phage	4.7e-158	100.0
WP_001281116.1\|31854_32247_-	hypothetical protein	A0A077SLJ1	Escherichia_phage	2.0e-71	99.2
31865:31881	attL	NA	NA	NA	NA
WP_000007769.1\|32424_32847_-	hypothetical protein	A0A1B0VCB0	Salmonella_phage	2.7e-58	100.0
WP_000890198.1\|32886_33675_-	hypothetical protein	A0A1B0V830	Salmonella_phage	7.3e-121	99.6
WP_161403143.1\|33688_33841_-	hypothetical protein	NA	NA	NA	NA
WP_001177860.1\|34137_34422_+	hypothetical protein	Q71TA2	Escherichia_phage	3.5e-49	100.0
WP_000472529.1\|34414_35320_+	recombination-associated protein RdgC	A0A077SK17	Escherichia_phage	1.6e-159	99.7
WP_023155377.1\|35316_37335_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	Q1MVI4	Enterobacteria_phage	0.0e+00	95.1
WP_000467133.1\|38986_39421_+	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	8.1e-74	100.0
WP_000146942.1\|39420_39585_+	DUF3927 family protein	Q1MVI2	Enterobacteria_phage	6.9e-18	98.1
WP_059339311.1\|40057_41422_+	replicative DNA helicase	O80281	Escherichia_phage	5.3e-252	99.3
WP_023155375.1\|41421_42420_+	hypothetical protein	Q71TK3	Escherichia_phage	1.4e-193	99.1
WP_000535201.1\|42466_43099_-	hypothetical protein	A0A077SK50	Escherichia_phage	9.0e-90	99.4
WP_000212015.1\|43091_44108_-	hypothetical protein	A0A077SLQ1	Escherichia_phage	4.5e-192	99.7
WP_000602717.1\|44109_44895_-	hypothetical protein	Q71T90	Escherichia_phage	4.6e-144	99.6
WP_000896801.1\|44881_45610_-	hypothetical protein	A0A077SK19	Escherichia_phage	9.3e-139	100.0
WP_001141908.1\|45613_46831_-	hypothetical protein	A0A077SL53	Escherichia_phage	1.1e-224	100.0
WP_000235789.1\|46840_47218_-	hypothetical protein	Q38620	Escherichia_phage	6.4e-67	99.2
WP_000840931.1\|47364_47610_+	hypothetical protein	Q71T86	Escherichia_phage	5.7e-40	100.0
WP_000943612.1\|47612_48191_+	VRR-NUC domain-containing protein	A0A077SLK0	Escherichia_phage	8.8e-108	100.0
WP_000095380.1\|48257_48413_+	hypothetical protein	A0A077SK20	Escherichia_phage	1.2e-19	100.0
WP_032144601.1\|48354_49017_+	hypothetical protein	A0A077SL54	Escherichia_phage	4.5e-124	100.0
WP_069356943.1\|48914_49541_+	norphogenetic protein	A0A077SK52	Escherichia_phage	3.6e-123	99.5
WP_001354545.1\|49537_50215_+	metallophosphoesterase	A0A077SLQ6	Escherichia_phage	7.6e-135	100.0
WP_000684849.1\|50211_50913_+	hypothetical protein	A0A077SLK3	Escherichia_phage	7.1e-144	100.0
WP_000107690.1\|51214_52477_+	hypothetical protein	A0A1B0V7L1	Salmonella_phage	1.6e-234	99.8
WP_032275633.1\|52549_53056_+	3'-phosphatase 5'-polynucleotide kinase phage-associated protein	A0A077SK53	Escherichia_phage	3.8e-91	97.0
WP_000675633.1\|53250_53979_+	hypothetical protein	Q71T76	Escherichia_phage	3.5e-138	97.8
WP_000158003.1\|54062_54266_+	hypothetical protein	A0A2R2Z313	Escherichia_phage	6.8e-31	94.0
WP_000476202.1\|54258_54498_+	hypothetical protein	S5MQM0	Escherichia_phage	2.0e-34	92.4
WP_001290016.1\|54494_55196_+	ead/Ea22-like family protein	A0A0U2QW67	Escherichia_phage	2.7e-50	55.0
WP_001018057.1\|55192_55483_+	DUF4752 family protein	A0A2I6TCB0	Escherichia_phage	1.2e-36	82.3
WP_059336898.1\|55479_56214_+	hypothetical protein	A0A2I6TCG8	Escherichia_phage	3.8e-39	54.6
WP_000215167.1\|56210_56510_+	hypothetical protein	A5VWB2	Enterobacteria_phage	1.3e-57	99.0
WP_000161574.1\|56511_56997_+	ead/Ea22-like family protein	A5VWB3	Enterobacteria_phage	3.1e-45	88.9
WP_000951712.1\|56998_57208_+	hypothetical protein	A0A0F6TJE4	Escherichia_coli_O157_typing_phage	2.0e-33	92.8
WP_000207969.1\|57204_57567_+	hypothetical protein	A0A1B0V865	Salmonella_phage	4.0e-58	98.3
WP_000797279.1\|57739_57928_+	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	1.4e-30	98.4
WP_000628758.1\|58441_59011_+	DUF551 domain-containing protein	G9L6B4	Escherichia_phage	1.4e-102	95.7
WP_000382636.1\|59001_59259_+	hypothetical protein	A0A077SLR0	Escherichia_phage	2.0e-40	97.6
WP_000002126.1\|59258_59540_+	ASCH domain-containing protein	A0A077SLL0	Escherichia_phage	3.4e-49	100.0
WP_000267998.1\|59563_59857_+	hypothetical protein	A0A077SK23	Escherichia_phage	4.2e-50	99.0
WP_000988652.1\|59863_60238_+	hypothetical protein	A0A077SL57	Escherichia_phage	1.2e-68	100.0
WP_000057460.1\|60219_60894_+	hypothetical protein	A0A077SK55	Escherichia_phage	1.1e-114	97.6
WP_001261541.1\|60890_61253_+	hypothetical protein	A0A1B0VBR1	Salmonella_phage	2.2e-56	99.2
WP_001062547.1\|62328_62685_-	hypothetical protein	A0A1B0VCG1	Salmonella_phage	3.1e-63	99.2
WP_001133673.1\|62685_63270_-	hypothetical protein	Q1MVE8	Enterobacteria_phage	1.5e-110	99.0
WP_000506724.1\|63444_63834_+	DNA repair protein	A0A077SK24	Escherichia_phage	6.4e-70	99.2
WP_001190712.1\|63906_64128_+	type II toxin-antitoxin system Phd/YefM family antitoxin	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
WP_001216045.1\|64127_64508_+	type II toxin-antitoxin system death-on-curing family toxin	Q71T66	Escherichia_phage	1.9e-63	100.0
WP_000113018.1\|64512_64692_+	hypothetical protein	Q71TH5	Escherichia_phage	1.2e-23	98.3
WP_000648833.1\|64719_65763_+	DUF968 domain-containing protein	A0A077SLM1	Escherichia_phage	1.1e-206	99.7
WP_001326849.1\|65851_66304_+	late promoter-activating protein	Q71T63	Escherichia_phage	3.0e-79	100.0
WP_000219618.1\|66389_67583_+	hypothetical protein	A0A077SL59	Escherichia_phage	4.7e-180	99.7
WP_000124159.1\|67582_69067_+	hypothetical protein	Q5QBP2	Enterobacteria_phage	4.3e-292	99.8
WP_000611656.1\|69091_69943_-	hypothetical protein	A0A077SLM8	Escherichia_phage	6.1e-158	99.6
WP_000874154.1\|70053_70263_-	hypothetical protein	Q5XLQ8	Enterobacteria_phage	4.8e-32	100.0
WP_000542336.1\|70867_71089_+	hypothetical protein	Q5QBN7	Enterobacteria_phage	4.5e-36	100.0
WP_001776219.1\|71096_72128_+\|integrase	tyrosine-type recombinase/integrase	Q71TG5	Escherichia_phage	4.9e-194	99.7
WP_001749391.1\|72178_72490_+	hypothetical protein	Q5QBN5	Enterobacteria_phage	2.1e-47	100.0
WP_001776220.1\|72737_73298_+	Ref family protein	Q5QBN4	Enterobacteria_phage	5.0e-100	98.9
WP_001408825.1\|73486_74128_+	hypothetical protein	A0A077SK30	Escherichia_phage	2.5e-111	97.2
WP_000072647.1\|74327_74936_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000747846.1\|75018_75267_-	hypothetical protein	Q71TG0	Escherichia_phage	1.8e-41	100.0
WP_000224043.1\|75263_75704_-	hypothetical protein	A0A077SLF0	Escherichia_phage	1.7e-79	100.0
WP_069356944.1\|75737_82505_-	N-6 DNA methylase	Q1MVN7	Enterobacteria_phage	0.0e+00	98.9
WP_069356945.1\|82580_84290_+\|portal	phage portal protein	Q1MVN6	Enterobacteria_phage	0.0e+00	99.5
82927:82943	attR	NA	NA	NA	NA
WP_000132937.1\|84282_85302_+\|head	head processing protein	Q71TR6	Escherichia_phage	4.4e-179	96.8
WP_001345478.1\|85593_86151_-	lysozyme	Q71TF3	Escherichia_phage	4.2e-107	100.0
WP_000068865.1\|86319_86808_+	single-stranded DNA-binding protein	A0A1B0VAF5	Salmonella_phage	5.0e-88	100.0
WP_001776225.1\|87005_87794_+	hypothetical protein	A0A077SK34	Escherichia_phage	4.0e-143	98.8
WP_001165936.1\|87823_88132_-	hypothetical protein	O21974	Escherichia_phage	5.4e-48	97.1
WP_001776226.1\|88121_91109_-	hypothetical protein	A0A1B0VFX4	Salmonella_phage	0.0e+00	99.6
WP_024200403.1\|91121_91487_-	hypothetical protein	Q1MVM8	Enterobacteria_phage	3.9e-45	98.3
WP_059339291.1\|91483_93403_-	hypothetical protein	A0A1B0V7H1	Salmonella_phage	0.0e+00	96.9
WP_001345482.1\|93404_94007_-	hypothetical protein	Q1MVM6	Enterobacteria_phage	5.4e-100	100.0
WP_000580776.1\|93993_94437_-	hypothetical protein	A0A077SK09	Escherichia_phage	1.3e-82	100.0
WP_000887652.1\|94433_94763_-\|holin	holin	Q37876	Escherichia_phage	1.3e-52	100.0
WP_000145199.1\|94837_95101_-	hypothetical protein	Q71TD9	Escherichia_phage	1.1e-22	67.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP014583

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014583_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_1

926466-926557

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014583_1

>merge|NZ_CP014583|1|926466-926557|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTCCCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP014583|1|1|926466-926557|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTCCCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_069357131.1\|919982_920621_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP014583.1\|WP_001028096.1\|924508_925003_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NZ_CP014583.1\|WP_001365086.1\|915980_919943_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP014583.1\|WP_069357134.1\|932232_932832_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP014583.1\|WP_024226939.1\|932828_935375_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP014583.1\|WP_000979516.1\|915716_915926_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014583.1\|WP_000024560.1\|931834_932140_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP014583.1\|WP_000420617.1\|930914_931835_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP014583.1\|WP_001126780.1\|922703_923090_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP014583.1\|WP_069357132.1\|923097_923898_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP014583.1\|WP_069357133.1\|929394_930654_-\|YccE-family-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP014583.1\|WP_001365093.1\|925023_926352_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP014583.1\|WP_001143120.1\|927597_927825_+\|YccJ-family-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP014583.1\|WP_001001183.1\|923907_924498_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP014583.1\|WP_069357135.1\|935374_936547_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992
NZ_CP014583.1\|WP_001307100.1\|921999_922692_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP014583.1\|WP_069357669.1\|920908_922000_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP014583.1\|WP_001151437.1\|926980_927577_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP014583.1\|WP_001044273.1\|927862_929104_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP014583.1\|WP_001120112.1\|936676_937369_+\|two-component-system-response-regulator-TorR	unknown	unknown	gnl\|CDD\|182711

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_069357131.1\|919982_920621_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	3.31602e-153
NZ_CP014583.1\|WP_001028096.1\|924508_925003_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	8.28716e-106
NZ_CP014583.1\|WP_001365086.1\|915980_919943_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP014583.1\|WP_069357134.1\|932232_932832_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	9.24929e-84
NZ_CP014583.1\|WP_024226939.1\|932828_935375_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP014583.1\|WP_000024560.1\|931834_932140_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	5.75956e-65
NZ_CP014583.1\|WP_000420617.1\|930914_931835_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP014583.1\|WP_001126780.1\|922703_923090_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	5.99808e-85
NZ_CP014583.1\|WP_069357132.1\|923097_923898_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	8.06106e-141
NZ_CP014583.1\|WP_069357133.1\|929394_930654_-\|YccE-family-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP014583.1\|WP_001365093.1\|925023_926352_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP014583.1\|WP_001143120.1\|927597_927825_+\|YccJ-family-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP014583.1\|WP_001001183.1\|923907_924498_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	2.57102e-129
NZ_CP014583.1\|WP_069357135.1\|935374_936547_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0
NZ_CP014583.1\|WP_001307100.1\|921999_922692_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	2.45431e-169
NZ_CP014583.1\|WP_069357669.1\|920908_922000_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP014583.1\|WP_001151437.1\|926980_927577_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	8.51484e-133
NZ_CP014583.1\|WP_001044273.1\|927862_929104_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP014583.1\|WP_001120112.1\|936676_937369_+\|two-component-system-response-regulator-TorR	gnl\|CDD\|182711	PRK10766, PRK10766, two-component system response regulator TorR.	5.89892e-138

>NZ_CP014583.1|WP_001365093.1|925023_926352_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP
>NZ_CP014583.1|WP_001028096.1|924508_925003_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
>NZ_CP014583.1|WP_001001183.1|923907_924498_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
>NZ_CP014583.1|WP_069357132.1|923097_923898_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRKRLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP014583.1|WP_001126780.1|922703_923090_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP014583.1|WP_001307100.1|921999_922692_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFAHIA
>NZ_CP014583.1|WP_069357669.1|920908_922000_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAVRMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPSAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP014583.1|WP_069357131.1|919982_920621_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGETLRDEIFFNQTVENVQRIIIEGIRPR
>NZ_CP014583.1|WP_001365086.1|915980_919943_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLENLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLVDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGRHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVAMLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELHKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGLTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP014583.1|WP_000979516.1|915716_915926_-|hypothetical-protein
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NZ_CP014583.1|WP_001151437.1|926980_927577_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP014583.1|WP_001143120.1|927597_927825_+|YccJ-family-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP014583.1|WP_001044273.1|927862_929104_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAAAVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECPPPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDANGFCPMDKFDSVLNEAVK
>NZ_CP014583.1|WP_069357133.1|929394_930654_-|YccE-family-protein
MGSNIHGISCTANNYLKQAWNDIKNEYEKNQTYSITLFENTLVCFMRLYNELRRKVNEEDTPCLECESLEKEFEEMQNDNDLSLFMRTLRTNDTQIYSGVSEGITYTIQYVRDIDIVRVSLPGRASESITDFKGYYWYGFMEYIENINACDDVFSEYCFDDENISVQPERINTPGISDLDSDIDLSGISFIQRETNQALGLKYAPVDGDGYCLLRAILVLKQHDYSWALVSYKMQKEVYNEFIKMVDKKTIEALVDTAFYNLREDVKTLFGVDLQSDNQIQGQSSLMSWSFLFFKKQFIDSCLNNEKCILHLPEFIFNDNKNLLALDTDTSDRIKAVKNFLAVLSDSICSLFIVNSNVASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKLNNKEMNAQLDYLNRYAIY
>NZ_CP014583.1|WP_000420617.1|930914_931835_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPAARGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP014583.1|WP_000024560.1|931834_932140_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
>NZ_CP014583.1|WP_069357134.1|932232_932832_-|molecular-chaperone-TorD
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIAPLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFAARCHQYDSFGFYAALSQLLLVLVECDHQNR
>NZ_CP014583.1|WP_024226939.1|932828_935375_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATEAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLSDHVHNAARIRYPMVRVDWLRKRHRSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYEQLKAKVAAGEVEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFQPYLLGEKDGQPKDAAWAEKLTGIDAESIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS
>NZ_CP014583.1|WP_069357135.1|935374_936547_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSACWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKSIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>NZ_CP014583.1|WP_001120112.1|936676_937369_+|two-component-system-response-regulator-TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC

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Crispr_ID: NZ_CP014583_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_2

1115608-1115756

Orphan

I-F

Consensus_repeat	Method
ATTTCTAAGCTGCCTGTACGGCAGTGAAC	CRISPRCasFinder
ATTTCTAAGCTGCCTGTACGGCAGTGAAC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP014583_2

>merge|NZ_CP014583|2|1115608-1115756|CRISPRCasFinder,PILER-CR
GCATTTTATCTGTCTGTACGGCAGTGAACATGGTGGGCGGGTGGAGTATGTTACCTGTGAATTTCTAAGCTGCCTGTACGGCAGTGAACGCGTTCGCAAAGGTTTTACCGCACCCCGTCGATTTCTAAGCTGCCTGTACGGCAGTGAAC

>NZ_CP014583|2|2|1115608-1115756|CRISPRCasFinder
GCATTTTATCTGTCTGTACGGCAGTGAAC	ATGGTGGGCGGGTGGAGTATGTTACCTGTGA
ATTTCTAAGCTGCCTGTACGGCAGTGAAC	GCGTTCGCAAAGGTTTTACCGCACCCCGTCG
ATTTCTAAGCTGCCTGTACGGCAGTGAAC

>NZ_CP014583|2|1|1115617-1115756|PILER-CR
CTGTCTGTACGGCAGTGAACATGGTGGGC	GGGTGGAGTATGTTACCTGTGAATTTCTAAG
CTGCCTGTACGGCAGTGAACGCGTTCGCA	AAGGTTTTACCGCACCCCGTCGATTTCTAAG
CTGCCTGTACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_000491142.1\|1126651_1127551_+\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287
NZ_CP014583.1\|WP_000228473.1\|1108359_1108854_-\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
NZ_CP014583.1\|WP_001202175.1\|1112253_1113975_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
NZ_CP014583.1\|WP_069357177.1\|1104157_1108225_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NZ_CP014583.1\|WP_000410785.1\|1118918_1119143_+\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NZ_CP014583.1\|WP_000886683.1\|1100654_1101947_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP014583.1\|WP_000188180.1\|1119215_1121162_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NZ_CP014583.1\|WP_001043619.1\|1110486_1112253_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NZ_CP014583.1\|WP_001040187.1\|1115005_1115224_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NZ_CP014583.1\|WP_069357180.1\|1123377_1125036_-\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NZ_CP014583.1\|WP_069357179.1\|1121158_1122274_-\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NZ_CP014583.1\|WP_069357175.1\|1102037_1103381_-\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NZ_CP014583.1\|WP_001298299.1\|1125461_1126157_+\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NZ_CP014583.1\|WP_001355621.1\|1122424_1123381_+\|VirK/YbjX-family-protein	unknown	unknown	gnl\|CDD\|225537
NZ_CP014583.1\|WP_069357176.1\|1103391_1104003_-\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NZ_CP014583.1\|WP_000520781.1\|1118275_1118596_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP014583.1\|WP_000458817.1\|1127694_1129347_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NZ_CP014583.1\|WP_069357178.1\|1114016_1114721_+\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP014583.1\|WP_000537418.1\|1109398_1110364_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NZ_CP014583.1\|WP_000934041.1\|1115968_1118245_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_000491142.1\|1126651_1127551_+\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	8.74036e-118
NZ_CP014583.1\|WP_000228473.1\|1108359_1108854_-\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
NZ_CP014583.1\|WP_001202175.1\|1112253_1113975_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP014583.1\|WP_069357177.1\|1104157_1108225_-\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NZ_CP014583.1\|WP_000410785.1\|1118918_1119143_+\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NZ_CP014583.1\|WP_000886683.1\|1100654_1101947_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP014583.1\|WP_000188180.1\|1119215_1121162_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NZ_CP014583.1\|WP_001043619.1\|1110486_1112253_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP014583.1\|WP_001040187.1\|1115005_1115224_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NZ_CP014583.1\|WP_069357180.1\|1123377_1125036_-\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NZ_CP014583.1\|WP_069357179.1\|1121158_1122274_-\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NZ_CP014583.1\|WP_069357175.1\|1102037_1103381_-\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP014583.1\|WP_001298299.1\|1125461_1126157_+\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	2.04944e-144
NZ_CP014583.1\|WP_001355621.1\|1122424_1123381_+\|VirK/YbjX-family-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	1.27645e-131
NZ_CP014583.1\|WP_069357176.1\|1103391_1104003_-\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	4.68714e-125
NZ_CP014583.1\|WP_000520781.1\|1118275_1118596_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
NZ_CP014583.1\|WP_000458817.1\|1127694_1129347_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NZ_CP014583.1\|WP_069357178.1\|1114016_1114721_+\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	4.77454e-138
NZ_CP014583.1\|WP_000537418.1\|1109398_1110364_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NZ_CP014583.1\|WP_000934041.1\|1115968_1118245_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0

>NZ_CP014583.1|WP_001040187.1|1115005_1115224_+|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NZ_CP014583.1|WP_069357178.1|1114016_1114721_+|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKLSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
>NZ_CP014583.1|WP_001202175.1|1112253_1113975_+|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRISDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NZ_CP014583.1|WP_001043619.1|1110486_1112253_+|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEVELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI
>NZ_CP014583.1|WP_000537418.1|1109398_1110364_+|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NZ_CP014583.1|WP_000228473.1|1108359_1108854_-|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NZ_CP014583.1|WP_069357177.1|1104157_1108225_-|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPSQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQAYQQPAAQEPLYQQPQSVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAGAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVPPQQQYQQPQQPVAPQPQYQQPQQQVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADCMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NZ_CP014583.1|WP_069357176.1|1103391_1104003_-|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSSVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NZ_CP014583.1|WP_069357175.1|1102037_1103381_-|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGTTTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAKVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPREIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NZ_CP014583.1|WP_000886683.1|1100654_1101947_-|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
>NZ_CP014583.1|WP_000934041.1|1115968_1118245_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NZ_CP014583.1|WP_000520781.1|1118275_1118596_-|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NZ_CP014583.1|WP_000410785.1|1118918_1119143_+|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NZ_CP014583.1|WP_000188180.1|1119215_1121162_-|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGITLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NZ_CP014583.1|WP_069357179.1|1121158_1122274_-|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPVDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NZ_CP014583.1|WP_001355621.1|1122424_1123381_+|VirK/YbjX-family-protein
MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG
>NZ_CP014583.1|WP_069357180.1|1123377_1125036_-|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLRPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NZ_CP014583.1|WP_001298299.1|1125461_1126157_+|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRD
>NZ_CP014583.1|WP_000491142.1|1126651_1127551_+|L-lysine-exporter-LysO
MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NZ_CP014583.1|WP_000458817.1|1127694_1129347_+|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA

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Crispr_ID: NZ_CP014583_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_3

1254831-1254975

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014583_3

>merge|NZ_CP014583|3|1254831-1254975|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGTAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTACCGGATGC

>NZ_CP014583|3|3|1254831-1254975|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGTAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTACCGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_097310820.1\|1247852_1249021_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP014583.1\|WP_069357195.1\|1249067_1249358_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014583.1\|WP_069357199.1\|1263150_1264209_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP014583.1\|WP_000815435.1\|1261181_1262177_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NZ_CP014583.1\|WP_071961483.1\|1252056_1252299_+\|excisionase	unknown	unknown	gnl\|CDD\|116439
NZ_CP014583.1\|WP_000891515.1\|1265838_1265988_-\|multidrug-efflux-pump-accessory-protein-AcrZ	unknown	unknown	gnl\|CDD\|371231
NZ_CP014583.1\|WP_069357198.1\|1254998_1257260_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NZ_CP014583.1\|WP_001303965.1\|1250423_1250723_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014583.1\|WP_069357197.1\|1252276_1253347_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271181
NZ_CP014583.1\|WP_024225840.1\|1253481_1254765_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP014583.1\|WP_000679973.1\|1260187_1261141_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP014583.1\|WP_085948186.1\|1250861_1252018_-\|IS3-like-element-IS600-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP014583.1\|WP_000213425.1\|1262331_1263150_+\|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase	unknown	unknown	gnl\|CDD\|182523
NZ_CP014583.1\|WP_069357196.1\|1249488_1250187_+\|DUF1311-domain-containing-protein	unknown	unknown	gnl\|CDD\|164889
NZ_CP014583.1\|WP_000763378.1\|1246766_1246988_+\|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|222775
NZ_CP014583.1\|WP_000723652.1\|1258951_1260004_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
NZ_CP014583.1\|WP_000113008.1\|1264900_1265674_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NZ_CP014583.1\|WP_069357193.1\|1246984_1247686_+\|ead/Ea22-like-family-protein	unknown	unknown	gnl\|CDD\|379401
NZ_CP014583.1\|WP_001036475.1\|1257442_1258876_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP014583.1\|WP_000604034.1\|1264211_1264901_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_097310820.1\|1247852_1249021_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.51237e-140
NZ_CP014583.1\|WP_069357199.1\|1263150_1264209_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP014583.1\|WP_000815435.1\|1261181_1262177_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NZ_CP014583.1\|WP_071961483.1\|1252056_1252299_+\|excisionase	gnl\|CDD\|116439	pfam07825, Exc, Excisionase-like protein. The phage-encoded excisionase protein (Xis) is involved in excisive recombination by regulating the assembly of the excisive intasome and by inhibiting viral integration. It adopts an unusual 'winged'-helix structure in which two alpha helices are packed against two extended strands. Also present in the structure is a two-stranded anti-parallel beta-sheet, whose strands are connected by a four-residue 'wing'. During interaction with DNA, helix alpha2 is thought to insert into the major groove, while the wing contacts the adjacent minor groove or phosphodiester backbone. The C-terminal region of Xis is involved in interaction with phage-encoded integrase (Int), and a putative C-terminal alpha helix may fold upon interaction with Int and/or DNA.	5.98231e-34
NZ_CP014583.1\|WP_000891515.1\|1265838_1265988_-\|multidrug-efflux-pump-accessory-protein-AcrZ	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
NZ_CP014583.1\|WP_069357198.1\|1254998_1257260_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NZ_CP014583.1\|WP_069357197.1\|1252276_1253347_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	8.75088e-62
NZ_CP014583.1\|WP_024225840.1\|1253481_1254765_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP014583.1\|WP_000679973.1\|1260187_1261141_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.20085e-82
NZ_CP014583.1\|WP_085948186.1\|1250861_1252018_-\|IS3-like-element-IS600-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.01838e-72
NZ_CP014583.1\|WP_000213425.1\|1262331_1263150_+\|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
NZ_CP014583.1\|WP_069357196.1\|1249488_1250187_+\|DUF1311-domain-containing-protein	gnl\|CDD\|164889	PHA02067, PHA02067, hypothetical protein.	2.74302e-16
NZ_CP014583.1\|WP_000763378.1\|1246766_1246988_+\|TraR/DksA-family-transcriptional-regulator	gnl\|CDD\|222775	PHA00080, PHA00080, DksA-like zinc finger domain containing protein.	6.38004e-27
NZ_CP014583.1\|WP_000723652.1\|1258951_1260004_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NZ_CP014583.1\|WP_000113008.1\|1264900_1265674_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
NZ_CP014583.1\|WP_069357193.1\|1246984_1247686_+\|ead/Ea22-like-family-protein	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	1.12168e-16
NZ_CP014583.1\|WP_001036475.1\|1257442_1258876_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NZ_CP014583.1\|WP_000604034.1\|1264211_1264901_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146

>NZ_CP014583.1|WP_024225840.1|1253481_1254765_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSRRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDHDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NZ_CP014583.1|WP_069357197.1|1252276_1253347_+|tyrosine-type-recombinase/integrase
MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQSNIELFSGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNPVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHVDALGISMKETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
>NZ_CP014583.1|WP_071961483.1|1252056_1252299_+|excisionase
MSVKLRLPQYLTLQEWNARQRRPRSLETVRRWVRECRIFPPPVKDGREYLFHESAVKVDLNRPVTGSLLKRIRNGKKAKS
>NZ_CP014583.1|WP_085948186.1|1250861_1252018_-|IS3-like-element-IS600-family-transposase
MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKGLGTPGSRTVAELESEILQLRKALNEARLERDIFKKSNSVFCTGVAEKYALIEQWRQQFPIEAMCQVFGVSRSGYYNWVQHEPSDRKQSDERLKLEIKVAHIRTRETYGTRRLQTELAENGIIVGRDRLARLRKELRLRCKQKRKFRATTNSNHNLPVAPNLLNQTFAPTAPNQVWVADLTYVATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKALFMALRSQRPPAGLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESLSHYRFNNRDEAISVIREYIEIFYNRQRRHSRLGNISPAAFREKYHQMAA
>NZ_CP014583.1|WP_001303965.1|1250423_1250723_+|hypothetical-protein
MACSTFNPLTLQKYQPDPEDLCSLCGGNHGKAAMIECKDKIHICLNCVDVLVDIKNEREDKKRSEAVRALDSWMRDGYSAAQIYDLAISKGEIPGVRIE
>NZ_CP014583.1|WP_069357196.1|1249488_1250187_+|DUF1311-domain-containing-protein
MKNILLASLLVASPGAFAASFDCQKASTAIEHKICDNERLSKLDEQLSSAYSSALKGNPENADTLKMVQRQWVNMRGKLTDNKALELAYLIQINGLKGLGSSVSVTAANDIPTSAQKHSEEQEETSKAEAKSVKNGNELTLESFRAKYVEVDGEYYSTTSIPRGSSFLFTCASRIADDQVNIWKKQAAKEGKIDLFFEVENHLHTAMLNANFQKLNSAPAKRGICNLINAVP
>NZ_CP014583.1|WP_069357195.1|1249067_1249358_+|hypothetical-protein
MAKFSAPLQLPDEEHEGETFNECPLSWGMSVEQYVSEFRKCLAEVRAQGVEMYADNLDNGADDAERGDFDDAVKFLRSEASGVRLFADQLRKGGNQ
>NZ_CP014583.1|WP_097310820.1|1247852_1249021_-|IS3-family-transposase
MKKRNFSAEFKRESAQLVVDQNYTVADAAKAMDIGLSTMTRWVKQLRDERQGKTPKASPITPEQIEIRELRKKLQRIEMENEIFKKGYRALDVRLPEQFSIIGKLRAHYPVVTLCHVFGVHRSSYRYWKNRPEKPDGRRAVLRSQVLELHNISHGSAGARSIATMATLIGFRMGRWLAGRLMKELGLVSCQQPAHRYKRGGREHVTIPNHLGRQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLLARKPVGWAMSFSPDSRLTIKALKMAWEIRSKPAGVMFHSDQGSHYTSRQFRQLLWRYQIKQSLSRRGNCWDNSPMERFFRSLKNEWIPVTGYMNFSDAAHEITDYIVGYYNALRPHEYNGGLPPNESENRYWKNSKAVASFC
>NZ_CP014583.1|WP_069357193.1|1246984_1247686_+|ead/Ea22-like-family-protein
MSEINYQALREIAKQATQGEWVAFISTGTGTYAVHTPGDKRCEDVIKWTGFDGLKNAENNARYVAAFNPKVALELLGEIKRLEDTNIDAMCRIAPLETKLAALVAENAGLKHAMAVTLDHVSVTDAGQAGVAAMIINDALHHSETPATDAFLAEIRAEARNEGINYTASRLAAAFNHGFINKSLREVFDVTRMILSAKEELANEPYPIDGLSGEYAEKSLEEWAEQIRKGVQS
>NZ_CP014583.1|WP_000763378.1|1246766_1246988_+|TraR/DksA-family-transcriptional-regulator
MADIIDSASEIEELQRNTAIKMRRLNYQTISATHCCECGDPIDERRRLVVQGCRTCASCQEDLELISKQRGSK
>NZ_CP014583.1|WP_069357198.1|1254998_1257260_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYTPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NZ_CP014583.1|WP_001036475.1|1257442_1258876_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NZ_CP014583.1|WP_000723652.1|1258951_1260004_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NZ_CP014583.1|WP_000679973.1|1260187_1261141_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIS
>NZ_CP014583.1|WP_000815435.1|1261181_1262177_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NZ_CP014583.1|WP_000213425.1|1262331_1263150_+|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NZ_CP014583.1|WP_069357199.1|1263150_1264209_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRSQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMSKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>NZ_CP014583.1|WP_000604034.1|1264211_1264901_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NZ_CP014583.1|WP_000113008.1|1264900_1265674_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFTVAGNALADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASEQKDFIIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>NZ_CP014583.1|WP_000891515.1|1265838_1265988_-|multidrug-efflux-pump-accessory-protein-AcrZ
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: NZ_CP014583_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_4

1906876-1907007

Orphan

Consensus_repeat	Method
AATGCAGACTAACCCGCAGATCCAGCAGCGAAGAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014583_4

>merge|NZ_CP014583|4|1906876-1907007|CRISPRCasFinder
AATGCAGACTAACCCGCAGATCCAGCAGCGAAGAGAGGCAGCGCGTGAGCGCATTCAGCCCGCCTCGCCTGAGCAGCGCCAGGCAGTCCGCGAGAAAATGCAGACTAACCCACAGATCCAGCAGCGAAGAGA

>NZ_CP014583|4|4|1906876-1907007|CRISPRCasFinder
AATGCAGACTAACCCGCAGATCCAGCAGCGAAGAGA	GGCAGCGCGTGAGCGCATTCAGCCCGCCTCGCCTGAGCAGCGCCAGGCAGTCCGCGAGAA
AATGCAGACTAACCCACAGATCCAGCAGCGAAGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_000969915.1\|1915142_1916516_+\|aromatic-amino-acid-transporter-AroP	unknown	unknown	gnl\|CDD\|182324
NZ_CP014583.1\|WP_000003820.1\|1911013_1913677_-\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	unknown	unknown	gnl\|CDD\|236500
NZ_CP014583.1\|WP_000923721.1\|1917408_1917960_-\|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD	unknown	unknown	gnl\|CDD\|236984
NZ_CP014583.1\|WP_000683335.1\|1894883_1895420_-\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|185321
NZ_CP014583.1\|WP_000360904.1\|1919143_1919584_+\|prepilin-peptidase-dependent-pilin	unknown	unknown	gnl\|CDD\|236718
NZ_CP014583.1\|WP_024225964.1\|1898062_1899613_-\|multicopper-oxidase-CueO	unknown	unknown	gnl\|CDD\|236810
NZ_CP014583.1\|WP_001295568.1\|1899778_1900126_+\|YacC-family-pilotin-like-protein	unknown	unknown	gnl\|CDD\|370620
NZ_CP014583.1\|WP_000102485.1\|1907357_1908782_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|180579
NZ_CP014583.1\|WP_024225966.1\|1909106_1910999_-\|pyruvate-dehydrogenase-complex-dihydrolipoyllysine-residue-acetyltransferase	unknown	unknown	gnl\|CDD\|236999
NZ_CP014583.1\|WP_000734287.1\|1901113_1901908_+\|adenosylmethionine-decarboxylase	unknown	unknown	gnl\|CDD\|235480
NZ_CP014583.1\|WP_000331776.1\|1913837_1914602_-\|pyruvate-dehydrogenase-complex-transcriptional-repressor-PdhR	unknown	unknown	gnl\|CDD\|181879
NZ_CP014583.1\|WP_000651599.1\|1894180_1894843_+\|carbonate-dehydratase	unknown	unknown	gnl\|CDD\|182460
NZ_CP014583.1\|WP_024225967.1\|1920968_1922171_+\|protein-transport-protein-HofC	unknown	unknown	gnl\|CDD\|182559
NZ_CP014583.1\|WP_001303793.1\|1902481_1905079_-\|bifunctional-aconitate-hydratase-2/2-methylisocitrate-dehydratase	unknown	unknown	gnl\|CDD\|236424
NZ_CP014583.1\|WP_001025153.1\|1919593_1920979_+\|type-II-secretion-system-protein-GspE	unknown	unknown	gnl\|CDD\|236694
NZ_CP014583.1\|WP_000384306.1\|1901944_1902307_-\|YacL-family-protein	unknown	unknown	gnl\|CDD\|235372
NZ_CP014583.1\|WP_001135174.1\|1918047_1918941_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|181612
NZ_CP014583.1\|WP_000150637.1\|1893145_1894072_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP014583.1\|WP_000818411.1\|1900231_1901098_+\|polyamine-aminopropyltransferase	unknown	unknown	gnl\|CDD\|234843
NZ_CP014583.1\|WP_024225963.1\|1895625_1898016_+\|quinoprotein-glucose-dehydrogenase	unknown	unknown	gnl\|CDD\|274418

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_000969915.1\|1915142_1916516_+\|aromatic-amino-acid-transporter-AroP	gnl\|CDD\|182324	PRK10238, PRK10238, aromatic amino acid transporter AroP.	0
NZ_CP014583.1\|WP_000003820.1\|1911013_1913677_-\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	gnl\|CDD\|236500	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed.	0
NZ_CP014583.1\|WP_000923721.1\|1917408_1917960_-\|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD	gnl\|CDD\|236984	PRK11789, PRK11789, 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD.	2.22246e-138
NZ_CP014583.1\|WP_000683335.1\|1894883_1895420_-\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|185321	PRK15423, PRK15423, hypoxanthine phosphoribosyltransferase; Provisional.	6.06525e-121
NZ_CP014583.1\|WP_000360904.1\|1919143_1919584_+\|prepilin-peptidase-dependent-pilin	gnl\|CDD\|236718	PRK10574, PRK10574, putative major pilin subunit; Provisional.	5.85141e-108
NZ_CP014583.1\|WP_024225964.1\|1898062_1899613_-\|multicopper-oxidase-CueO	gnl\|CDD\|236810	PRK10965, PRK10965, multicopper oxidase; Provisional.	0
NZ_CP014583.1\|WP_001295568.1\|1899778_1900126_+\|YacC-family-pilotin-like-protein	gnl\|CDD\|370620	pfam09691, T2SS_PulS_OutS, Type II secretion system pilotin lipoprotein (PulS_OutS). This family comprises lipoproteins from four gamma proteobacterial species: PulS protein of Klebsiella pneumoniae (P20440), the OutS protein of Erwinia chrysanthemi (Q01567) and Pectobacterium chrysanthemi, and the functionally uncharacterized E. coli protein EtpO. PulS and OutS have been shown to interact with and facilitate insertion of secretins into the outer membrane, suggesting a chaperone-like, or piloting function for members of this family. In the pilotin from this four-helix protein from enterohemorrhagic Escherichia coli, the straight helix alpha2, the curved helix alpha3 and the bent helix alpha4 surround the central N-terminal helix alpha1. These helices create a prominent groove, mainly formed by side chains of helices 1,2 and 3 suggesting this groove is important as a binding site.	8.48865e-08
NZ_CP014583.1\|WP_000102485.1\|1907357_1908782_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|180579	PRK06467, PRK06467, dihydrolipoamide dehydrogenase; Reviewed.	0
NZ_CP014583.1\|WP_024225966.1\|1909106_1910999_-\|pyruvate-dehydrogenase-complex-dihydrolipoyllysine-residue-acetyltransferase	gnl\|CDD\|236999	PRK11854, aceF, pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated.	0
NZ_CP014583.1\|WP_000734287.1\|1901113_1901908_+\|adenosylmethionine-decarboxylase	gnl\|CDD\|235480	PRK05462, PRK05462, adenosylmethionine decarboxylase.	0
NZ_CP014583.1\|WP_000331776.1\|1913837_1914602_-\|pyruvate-dehydrogenase-complex-transcriptional-repressor-PdhR	gnl\|CDD\|181879	PRK09464, pdhR, pyruvate dehydrogenase complex transcriptional repressor PdhR.	2.65103e-167
NZ_CP014583.1\|WP_000651599.1\|1894180_1894843_+\|carbonate-dehydratase	gnl\|CDD\|182460	PRK10437, PRK10437, carbonic anhydrase; Provisional.	2.75383e-171
NZ_CP014583.1\|WP_024225967.1\|1920968_1922171_+\|protein-transport-protein-HofC	gnl\|CDD\|182559	PRK10573, PRK10573, protein transport protein HofC.	0
NZ_CP014583.1\|WP_001303793.1\|1902481_1905079_-\|bifunctional-aconitate-hydratase-2/2-methylisocitrate-dehydratase	gnl\|CDD\|236424	PRK09238, PRK09238, bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated.	0
NZ_CP014583.1\|WP_001025153.1\|1919593_1920979_+\|type-II-secretion-system-protein-GspE	gnl\|CDD\|236694	PRK10436, PRK10436, hypothetical protein; Provisional.	0
NZ_CP014583.1\|WP_000384306.1\|1901944_1902307_-\|YacL-family-protein	gnl\|CDD\|235372	PRK05248, PRK05248, hypothetical protein; Provisional.	3.86085e-68
NZ_CP014583.1\|WP_001135174.1\|1918047_1918941_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|181612	PRK09016, PRK09016, carboxylating nicotinate-nucleotide diphosphorylase.	0
NZ_CP014583.1\|WP_000150637.1\|1893145_1894072_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.41864e-103
NZ_CP014583.1\|WP_000818411.1\|1900231_1901098_+\|polyamine-aminopropyltransferase	gnl\|CDD\|234843	PRK00811, PRK00811, polyamine aminopropyltransferase.	2.3388e-178
NZ_CP014583.1\|WP_024225963.1\|1895625_1898016_+\|quinoprotein-glucose-dehydrogenase	gnl\|CDD\|274418	TIGR03074, PQQ_membr_DH, membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family. This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases.	0

>NZ_CP014583.1|WP_001303793.1|1902481_1905079_-|bifunctional-aconitate-hydratase-2/2-methylisocitrate-dehydratase
MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEAAYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKADGVIFQTAV
>NZ_CP014583.1|WP_000384306.1|1901944_1902307_-|YacL-family-protein
MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
>NZ_CP014583.1|WP_000734287.1|1901113_1901908_+|adenosylmethionine-decarboxylase
MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
>NZ_CP014583.1|WP_000818411.1|1900231_1901098_+|polyamine-aminopropyltransferase
MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS
>NZ_CP014583.1|WP_001295568.1|1899778_1900126_+|YacC-family-pilotin-like-protein
MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKNDCGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKALARDSLSLLAYVK
>NZ_CP014583.1|WP_024225964.1|1898062_1899613_-|multicopper-oxidase-CueO
MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDARNRIQLTIGAGQSTFGEKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVNELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGNMNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISSVGDMMLHPFHIHGTQFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHNAPKEHAYMAHCHLLEHEDTGMMLGFTV
>NZ_CP014583.1|WP_024225963.1|1895625_1898016_+|quinoprotein-glucose-dehydrogenase
MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWCSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDTNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPKKDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
>NZ_CP014583.1|WP_000683335.1|1894883_1895420_-|hypoxanthine-phosphoribosyltransferase
MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLDE
>NZ_CP014583.1|WP_000651599.1|1894180_1894843_+|carbonate-dehydratase
MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGHSTIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHANHK
>NZ_CP014583.1|WP_000150637.1|1893145_1894072_-|ABC-transporter-ATP-binding-protein
MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGKSTTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQAGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLILDEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENTSMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLSEQGIQVLSMRNKANRLEELFVSLVNEKQGDRA
>NZ_CP014583.1|WP_000102485.1|1907357_1908782_-|dihydrolipoyl-dehydrogenase
MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNPKAKKK
>NZ_CP014583.1|WP_024225966.1|1909106_1910999_-|pyruvate-dehydrogenase-complex-dihydrolipoyllysine-residue-acetyltransferase
MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAAAAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEIKVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDEVEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIRRLAREFGINLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKVDFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVNAPEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSDIRRLVM
>NZ_CP014583.1|WP_000003820.1|1911013_1913677_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type
MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQEQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTIKGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFNIDADKVNPRLA
>NZ_CP014583.1|WP_000331776.1|1913837_1914602_-|pyruvate-dehydrogenase-complex-transcriptional-repressor-PdhR
MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLETRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEAAHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAREASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN
>NZ_CP014583.1|WP_000969915.1|1915142_1916516_+|aromatic-amino-acid-transporter-AroP
MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGVVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTAKAVKAH
>NZ_CP014583.1|WP_000923721.1|1917408_1917960_-|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD
MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFGGPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQYQGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIAKNMTGHCDIAPDRKTDPGPAFDWARFRVLVSKETT
>NZ_CP014583.1|WP_001135174.1|1918047_1918941_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANNDITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQSLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLRSALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVENLEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVDFISVGALTKHVQALDLSMRFR
>NZ_CP014583.1|WP_000360904.1|1919143_1919584_+|prepilin-peptidase-dependent-pilin
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN
>NZ_CP014583.1|WP_001025153.1|1919593_1920979_+|type-II-secretion-system-protein-GspE
MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFATTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHIEPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVELAGNAVSFRIATLPCRGGEKVVLRLLQQVSQALDVNTLGMQPLQLADFAHALQQPQGLVLVTGPTGSGKTVTLYSALQTLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGVLRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVARWMLSSALTLVIAQRLVRKLCPHCRQQQGEPIHIPDTVWPSPLPHWQAPGCVHCYHGFYGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEELIRVLGMPHGE
>NZ_CP014583.1|WP_024225967.1|1920968_1922171_+|protein-transport-protein-HofC
MASKQLWRWHGITGDGNAHDGMLWAESRALLLMALQQQMVTPLSLKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAHDLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVKSALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSWLLVLFGFLLAIANKLLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNTGEFSPLCLQLVRTGEASGSLDLMLDNLAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMSGMG

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Crispr_ID: NZ_CP014583_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_5

1969728-1969843

Orphan

Consensus_repeat	Method
AACGCCTGATGCGACGCTGACGCGTCTTATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014583_5

>merge|NZ_CP014583|5|1969728-1969843|CRISPRCasFinder
AACGCCTGATGCGACGCTGACGCGTCTTATCTGGCCTACACGCTGCGATTTTGTAGGCCGGATAAGCAAAGCGCATCCGGCATTCAACGCCTGATGCGACGCTGGCGCGTCTTATC

>NZ_CP014583|5|5|1969728-1969843|CRISPRCasFinder
AACGCCTGATGCGACGCTGACGCGTCTTATC	TGGCCTACACGCTGCGATTTTGTAGGCCGGATAAGCAAAGCGCATCCGGCATTC
AACGCCTGATGCGACGCTGGCGCGTCTTATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_000888666.1\|1969907_1970603_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP014583.1\|WP_000746151.1\|1977956_1980311_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP014583.1\|WP_000610901.1\|1983459_1983837_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP014583.1\|WP_000800457.1\|1980363_1981650_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP014583.1\|WP_001248770.1\|1959067_1959199_-\|glucose-uptake-inhibitor-SgrT	unknown	unknown	gnl\|CDD\|374203
NZ_CP014583.1\|WP_000235700.1\|1962065_1963676_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	unknown	unknown	gnl\|CDD\|181853
NZ_CP014583.1\|WP_069357271.1\|1970677_1973029_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP014583.1\|WP_001295536.1\|1961106_1962090_+\|thiamine-ABC-transporter-substrate-binding-subunit	unknown	unknown	gnl\|CDD\|236883
NZ_CP014583.1\|WP_000637846.1\|1957787_1958966_-\|sugar-efflux-transporter-SetA	unknown	unknown	gnl\|CDD\|129977
NZ_CP014583.1\|WP_001200573.1\|1976886_1977702_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP014583.1\|WP_001355662.1\|1959287_1960943_+\|DNA-binding-transcriptional-regulator-SgrR	unknown	unknown	gnl\|CDD\|184188
NZ_CP014583.1\|WP_001148403.1\|1964427_1965192_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP014583.1\|WP_069357270.1\|1968205_1969708_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP014583.1\|WP_001300811.1\|1965277_1966156_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP014583.1\|WP_000241259.1\|1981649_1982639_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP014583.1\|WP_000951769.1\|1966494_1968195_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP014583.1\|WP_000916285.1\|1963659_1964358_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	unknown	unknown	gnl\|CDD\|182716
NZ_CP014583.1\|WP_001117011.1\|1973192_1976099_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP014583.1\|WP_001065358.1\|1982635_1983457_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP014583.1\|WP_000525175.1\|1976110_1976770_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_000888666.1\|1969907_1970603_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	9.28933e-180
NZ_CP014583.1\|WP_000746151.1\|1977956_1980311_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP014583.1\|WP_000610901.1\|1983459_1983837_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	3.63315e-76
NZ_CP014583.1\|WP_000800457.1\|1980363_1981650_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP014583.1\|WP_001248770.1\|1959067_1959199_-\|glucose-uptake-inhibitor-SgrT	gnl\|CDD\|374203	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT.	0.00206924
NZ_CP014583.1\|WP_000235700.1\|1962065_1963676_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	gnl\|CDD\|181853	PRK09433, thiP, thiamine transporter membrane protein; Reviewed.	0
NZ_CP014583.1\|WP_069357271.1\|1970677_1973029_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP014583.1\|WP_001295536.1\|1961106_1962090_+\|thiamine-ABC-transporter-substrate-binding-subunit	gnl\|CDD\|236883	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional.	0
NZ_CP014583.1\|WP_000637846.1\|1957787_1958966_-\|sugar-efflux-transporter-SetA	gnl\|CDD\|129977	TIGR00899, Sugar_efflux_transporter_A, sugar efflux transporter. This family of proteins is an efflux system for lactose, glucose, aromatic glucosides and galactosides, cellobiose, maltose, a-methyl glucoside and other sugar compounds. They are found in both gram-negative and gram-postitive bacteria. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP014583.1\|WP_001200573.1\|1976886_1977702_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.09407e-169
NZ_CP014583.1\|WP_001355662.1\|1959287_1960943_+\|DNA-binding-transcriptional-regulator-SgrR	gnl\|CDD\|184188	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR.	0
NZ_CP014583.1\|WP_001148403.1\|1964427_1965192_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	2.87417e-49
NZ_CP014583.1\|WP_069357270.1\|1968205_1969708_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP014583.1\|WP_001300811.1\|1965277_1966156_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP014583.1\|WP_000241259.1\|1981649_1982639_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP014583.1\|WP_000951769.1\|1966494_1968195_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP014583.1\|WP_000916285.1\|1963659_1964358_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	gnl\|CDD\|182716	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ.	3.50301e-164
NZ_CP014583.1\|WP_001117011.1\|1973192_1976099_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP014583.1\|WP_001065358.1\|1982635_1983457_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.1992e-148
NZ_CP014583.1\|WP_000525175.1\|1976110_1976770_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	1.55263e-158

>NZ_CP014583.1|WP_069357270.1|1968205_1969708_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGSHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
>NZ_CP014583.1|WP_000951769.1|1966494_1968195_+|ribulokinase
MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
>NZ_CP014583.1|WP_001300811.1|1965277_1966156_-|arabinose-operon-transcriptional-regulator-AraC
MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>NZ_CP014583.1|WP_001148403.1|1964427_1965192_-|DedA-family-protein
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV
>NZ_CP014583.1|WP_000916285.1|1963659_1964358_+|thiamine-ABC-transporter-ATP-binding-protein-ThiQ
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQHKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTDELLSGKASASALLGITG
>NZ_CP014583.1|WP_000235700.1|1962065_1963676_+|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGNWVAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFTVIEKLPGRNVKTD
>NZ_CP014583.1|WP_001295536.1|1961106_1962090_+|thiamine-ABC-transporter-substrate-binding-subunit
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPKIKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
>NZ_CP014583.1|WP_001355662.1|1959287_1960943_+|DNA-binding-transcriptional-regulator-SgrR
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANKQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
>NZ_CP014583.1|WP_001248770.1|1959067_1959199_-|glucose-uptake-inhibitor-SgrT
MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES
>NZ_CP014583.1|WP_000637846.1|1957787_1958966_-|sugar-efflux-transporter-SetA
MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREVGAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRHYLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPLAFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVRMLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVKRYGKRRMMVIAVAAGVLFYTGLIFFHSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMPGRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
>NZ_CP014583.1|WP_000888666.1|1969907_1970603_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP014583.1|WP_069357271.1|1970677_1973029_+|DNA-polymerase-II
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVANIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>NZ_CP014583.1|WP_001117011.1|1973192_1976099_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
>NZ_CP014583.1|WP_000525175.1|1976110_1976770_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPHLLLHAEMLTITHPAYGNSMTFKAPADF
>NZ_CP014583.1|WP_001200573.1|1976886_1977702_-|co-chaperone-DjlA
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
>NZ_CP014583.1|WP_000746151.1|1977956_1980311_+|LPS-assembly-protein-LptD
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
>NZ_CP014583.1|WP_000800457.1|1980363_1981650_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
>NZ_CP014583.1|WP_000241259.1|1981649_1982639_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
>NZ_CP014583.1|WP_001065358.1|1982635_1983457_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKDQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
>NZ_CP014583.1|WP_000610901.1|1983459_1983837_+|Co2+/Mg2+-efflux-protein-ApaG
MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH

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Crispr_ID: NZ_CP014583_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_6

3546002-3546122

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014583_6

>merge|NZ_CP014583|6|3546002-3546122|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGGGTG

>NZ_CP014583|6|6|3546002-3546122|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTG	CTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_024226833.1\|3546379_3547081_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP014583.1\|WP_000145828.1\|3533722_3534067_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP014583.1\|WP_000785722.1\|3551311_3551716_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP014583.1\|WP_000031415.1\|3551718_3552024_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP014583.1\|WP_069357440.1\|3538902_3541197_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NZ_CP014583.1\|WP_001297162.1\|3537660_3538869_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP014583.1\|WP_000719990.1\|3541210_3541600_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP014583.1\|WP_000096086.1\|3551022_3551322_-\|YqjK-like-family-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP014583.1\|WP_000401598.1\|3543311_3544643_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP014583.1\|WP_000732233.1\|3550444_3550837_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP014583.1\|WP_000384145.1\|3548730_3549096_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP014583.1\|WP_000104211.1\|3534255_3535194_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP014583.1\|WP_000107712.1\|3536303_3537635_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP014583.1\|WP_001295544.1\|3546192_3546357_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014583.1\|WP_069357441.1\|3549388_3550375_-\|glutathionyl-hydroquinone-reductase-YqjG	unknown	unknown	gnl\|CDD\|223512
NZ_CP014583.1\|WP_001198807.1\|3548132_3548489_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP014583.1\|WP_001041010.1\|3547185_3548082_+\|DNA-binding-transcriptional-regulator-YhaJ	unknown	unknown	gnl\|CDD\|176122
NZ_CP014583.1\|WP_000460519.1\|3544670_3545981_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP014583.1\|WP_069357439.1\|3535292_3536282_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP014583.1\|WP_000622115.1\|3541671_3543036_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_000145828.1\|3533722_3534067_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	6.78402e-66
NZ_CP014583.1\|WP_000785722.1\|3551311_3551716_-\|phage-holin-family-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP014583.1\|WP_000031415.1\|3551718_3552024_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP014583.1\|WP_069357440.1\|3538902_3541197_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP014583.1\|WP_001297162.1\|3537660_3538869_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP014583.1\|WP_069357439.1\|3535292_3536282_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP014583.1\|WP_000096086.1\|3551022_3551322_-\|YqjK-like-family-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP014583.1\|WP_000401598.1\|3543311_3544643_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53913e-167
NZ_CP014583.1\|WP_000732233.1\|3550444_3550837_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	3.31068e-25
NZ_CP014583.1\|WP_000384145.1\|3548730_3549096_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
NZ_CP014583.1\|WP_000104211.1\|3534255_3535194_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP014583.1\|WP_000107712.1\|3536303_3537635_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP014583.1\|WP_000719990.1\|3541210_3541600_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP014583.1\|WP_069357441.1\|3549388_3550375_-\|glutathionyl-hydroquinone-reductase-YqjG	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP014583.1\|WP_001198807.1\|3548132_3548489_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.17161e-38
NZ_CP014583.1\|WP_001041010.1\|3547185_3548082_+\|DNA-binding-transcriptional-regulator-YhaJ	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
NZ_CP014583.1\|WP_000460519.1\|3544670_3545981_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0
NZ_CP014583.1\|WP_024226833.1\|3546379_3547081_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	6.08497e-67
NZ_CP014583.1\|WP_000622115.1\|3541671_3543036_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0

>NZ_CP014583.1|WP_000460519.1|3544670_3545981_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP014583.1|WP_000401598.1|3543311_3544643_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP014583.1|WP_000622115.1|3541671_3543036_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP014583.1|WP_000719990.1|3541210_3541600_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP014583.1|WP_069357440.1|3538902_3541197_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTLEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP014583.1|WP_001297162.1|3537660_3538869_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP014583.1|WP_000107712.1|3536303_3537635_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSKPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP014583.1|WP_069357439.1|3535292_3536282_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIETKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP014583.1|WP_000104211.1|3534255_3535194_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP014583.1|WP_000145828.1|3533722_3534067_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQAKFELNLISKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP014583.1|WP_001295544.1|3546192_3546357_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP014583.1|WP_024226833.1|3546379_3547081_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSDHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>NZ_CP014583.1|WP_001041010.1|3547185_3548082_+|DNA-binding-transcriptional-regulator-YhaJ
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>NZ_CP014583.1|WP_001198807.1|3548132_3548489_-|DUF805-domain-containing-protein
MQWYLSVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLELPYLSMLYLLATFLPVLALAIRRLHDTDRSGAWALLFFVPFIGWLVLLVFFCTEGTSGSNRYGNDPKFGSN
>NZ_CP014583.1|WP_000384145.1|3548730_3549096_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP014583.1|WP_069357441.1|3549388_3550375_-|glutathionyl-hydroquinone-reductase-YqjG
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGPHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP014583.1|WP_000732233.1|3550444_3550837_-|DoxX-family-protein
MKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP014583.1|WP_000096086.1|3551022_3551322_-|YqjK-like-family-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP014583.1|WP_000785722.1|3551311_3551716_-|phage-holin-family-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP014583.1|WP_000031415.1|3551718_3552024_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: NZ_CP014583_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_7

4039124-4039212

Unclear

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014583_7

>merge|NZ_CP014583|7|4039124-4039212|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCGAATAGCAATAGTCCATAGATTTGCGAAAACAGGTGTTCCCCGCGCCAGCGGGGATAAACC

>NZ_CP014583|7|7|4039124-4039212|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_069357498.1\|4039850_4041329_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP014583.1\|WP_001268450.1\|4036947_4037820_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP014583.1\|WP_001130266.1\|4048453_4049029_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP014583.1\|WP_024226273.1\|4035589_4036888_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP014583.1\|WP_001299652.1\|4046669_4047449_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP014583.1\|WP_001071648.1\|4032845_4033637_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP014583.1\|WP_000581937.1\|4032191_4032440_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP014583.1\|WP_000021321.1\|4042951_4043737_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP014583.1\|WP_000046790.1\|4028530_4029832_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP014583.1\|WP_001288227.1\|4037833_4037974_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014583.1\|WP_172907124.1\|4045282_4046692_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP014583.1\|WP_001199979.1\|4038112_4038784_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP014583.1\|WP_000109367.1\|4049045_4049306_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP014583.1\|WP_024226276.1\|4043806_4045261_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP014583.1\|WP_000210878.1\|4033864_4035502_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP014583.1\|WP_001501379.1\|4047445_4048306_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP014583.1\|WP_000254738.1\|4032439_4032775_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP014583.1\|WP_069357500.1\|4049296_4050568_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP014583.1\|WP_069357497.1\|4029879_4032114_+\|GTP-diphosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP014583.1\|WP_001164581.1\|4041355_4042633_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_069357498.1\|4039850_4041329_-\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.89419e-109
NZ_CP014583.1\|WP_001268450.1\|4036947_4037820_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	3.79081e-101
NZ_CP014583.1\|WP_001130266.1\|4048453_4049029_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP014583.1\|WP_024226273.1\|4035589_4036888_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP014583.1\|WP_001299652.1\|4046669_4047449_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.56693e-62
NZ_CP014583.1\|WP_001071648.1\|4032845_4033637_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP014583.1\|WP_000581937.1\|4032191_4032440_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP014583.1\|WP_000046790.1\|4028530_4029832_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP014583.1\|WP_000021321.1\|4042951_4043737_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.84461e-140
NZ_CP014583.1\|WP_172907124.1\|4045282_4046692_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00857e-51
NZ_CP014583.1\|WP_001199979.1\|4038112_4038784_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.23739e-155
NZ_CP014583.1\|WP_000109367.1\|4049045_4049306_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	8.55479e-42
NZ_CP014583.1\|WP_024226276.1\|4043806_4045261_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	8.373e-83
NZ_CP014583.1\|WP_000210878.1\|4033864_4035502_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP014583.1\|WP_001501379.1\|4047445_4048306_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	3.33557e-88
NZ_CP014583.1\|WP_000254738.1\|4032439_4032775_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP014583.1\|WP_069357500.1\|4049296_4050568_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	2.47098e-127
NZ_CP014583.1\|WP_069357497.1\|4029879_4032114_+\|GTP-diphosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP014583.1\|WP_001164581.1\|4041355_4042633_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	2.41032e-29

>NZ_CP014583.1|WP_001199979.1|4038112_4038784_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVISRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP014583.1|WP_001288227.1|4037833_4037974_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNESKITDAAVNLFIQI
>NZ_CP014583.1|WP_001268450.1|4036947_4037820_-|YgcG-family-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKFAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVCISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGKSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>NZ_CP014583.1|WP_024226273.1|4035589_4036888_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIALALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP014583.1|WP_000210878.1|4033864_4035502_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP014583.1|WP_001071648.1|4032845_4033637_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP014583.1|WP_000254738.1|4032439_4032775_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP014583.1|WP_000581937.1|4032191_4032440_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP014583.1|WP_069357497.1|4029879_4032114_+|GTP-diphosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLTAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP014583.1|WP_000046790.1|4028530_4029832_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLGSLQAIRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP014583.1|WP_069357498.1|4039850_4041329_-|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPACRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP014583.1|WP_001164581.1|4041355_4042633_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP014583.1|WP_000021321.1|4042951_4043737_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP014583.1|WP_024226276.1|4043806_4045261_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMTEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP014583.1|WP_172907124.1|4045282_4046692_+|MFS-transporter
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHCYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP014583.1|WP_001299652.1|4046669_4047449_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP014583.1|WP_001501379.1|4047445_4048306_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRGLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP014583.1|WP_001130266.1|4048453_4049029_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP014583.1|WP_000109367.1|4049045_4049306_-|ferredoxin-family-protein
MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP014583.1|WP_069357500.1|4049296_4050568_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEEEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRIPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDILQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: NZ_CP014583_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014583_8

4064927-4065138

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP014583_8

>merge|NZ_CP014583|8|4064927-4065138|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGAATTTGAGGCGGGGCGATCAATTGAGCCGTAGTGTTCCCCGCGCCAGCGGGGATAAACCGAATAGCGGGTACGGCTGAAAAGTGGATTTTACGTGTTCCCCGCGCCAGCGGGGATAAACCGTCCGTTTGGTCCACCAAATGTTTGATGCTTCAGTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP014583|8|2|4064927-4065138|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATTTGAGGCGGGGCGATCAATTGAGCCGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAGCGGGTACGGCTGAAAAGTGGATTTTAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCCGTTTGGTCCACCAAATGTTTGATGCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP014583|8|8|4064927-4065138|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATTTGAGGCGGGGCGATCAATTGAGCCGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAGCGGGTACGGCTGAAAAGTGGATTTTAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCCGTTTGGTCCACCAAATGTTTGATGCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP014583|8|1|4064927-4065138|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATTTGAGGCGGGGCGATCAATTGAGCCGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAGCGGGTACGGCTGAAAAGTGGATTTTAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCCGTTTGGTCCACCAAATGTTTGATGCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014583.1\|WP_001246104.1\|4069500_4069824_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP014583.1\|WP_001090361.1\|4067418_4068846_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP014583.1\|WP_001219242.1\|4071057_4071537_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP014583.1\|WP_000246140.1\|4070347_4071058_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP014583.1\|WP_000039850.1\|4054912_4055647_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP014583.1\|WP_001295182.1\|4072563_4073325_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP014583.1\|WP_000063176.1\|4064536_4064830_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP014583.1\|WP_000085072.1\|4062241_4062988_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP014583.1\|WP_024226281.1\|4059053_4060613_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP014583.1\|WP_000568926.1\|4071533_4072583_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP014583.1\|WP_000144855.1\|4063616_4064540_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP014583.1\|WP_000956458.1\|4055911_4056064_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP014583.1\|WP_000372106.1\|4066508_4067417_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP014583.1\|WP_001173673.1\|4068845_4069451_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP014583.1\|WP_000206407.1\|4061157_4062231_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP014583.1\|WP_000490402.1\|4065219_4066257_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP014583.1\|WP_069357501.1\|4056256_4058956_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP014583.1\|WP_069357502.1\|4060609_4061143_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP014583.1\|WP_000281454.1\|4062969_4063620_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP014583.1\|WP_000517476.1\|4070017_4070329_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156

Protein	Function_ID	Function_description	E-value
NZ_CP014583.1\|WP_001246104.1\|4069500_4069824_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP014583.1\|WP_001090361.1\|4067418_4068846_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP014583.1\|WP_001219242.1\|4071057_4071537_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP014583.1\|WP_000246140.1\|4070347_4071058_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	5.68505e-122
NZ_CP014583.1\|WP_000039850.1\|4054912_4055647_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	2.39575e-137
NZ_CP014583.1\|WP_001295182.1\|4072563_4073325_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP014583.1\|WP_000063176.1\|4064536_4064830_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP014583.1\|WP_000085072.1\|4062241_4062988_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.20842e-47
NZ_CP014583.1\|WP_024226281.1\|4059053_4060613_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	7.29179e-164
NZ_CP014583.1\|WP_000568926.1\|4071533_4072583_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP014583.1\|WP_000144855.1\|4063616_4064540_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.10193e-157
NZ_CP014583.1\|WP_000956458.1\|4055911_4056064_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP014583.1\|WP_000372106.1\|4066508_4067417_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP014583.1\|WP_001173673.1\|4068845_4069451_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP014583.1\|WP_000206407.1\|4061157_4062231_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	6.3804e-147
NZ_CP014583.1\|WP_000490402.1\|4065219_4066257_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP014583.1\|WP_069357501.1\|4056256_4058956_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	4.52878e-178
NZ_CP014583.1\|WP_069357502.1\|4060609_4061143_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	4.14942e-29
NZ_CP014583.1\|WP_000281454.1\|4062969_4063620_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.4219e-90
NZ_CP014583.1\|WP_000517476.1\|4070017_4070329_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62

>NZ_CP014583.1|WP_000063176.1|4064536_4064830_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP014583.1|WP_000144855.1|4063616_4064540_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRGTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHWGRGG
>NZ_CP014583.1|WP_000281454.1|4062969_4063620_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRPFVSELRTGQSLCFNLRANPTICKAGKRHDLLMEAKRQVKGQAEGRDIWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTAPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP014583.1|WP_000085072.1|4062241_4062988_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDTLRNAYQQYQDHFRKLKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP014583.1|WP_000206407.1|4061157_4062231_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDSGSPKTVILGGATRLRVSSQSLKRAWRTSELFEQALAGHIGVRSGRIAREAATILIEKGIEDKKAIEWAVEIADYLGKAKKDKKQKNDKKPKDPLTSAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEKDLALLRKDRMAVDIAMFGRMLAKKPGFNVEAACQVAHAFGVSETIVENDFFTAVDDLRQASEDAGAGHVDETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLEVAVQRITTLRENMNTVYEQKTDYASFDVMNKQGSMKDVLDFICA
>NZ_CP014583.1|WP_069357502.1|4060609_4061143_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKDEHKVALRKWHEELQDKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWLDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMKKGRFTRLLAVKTPDDLLRQLRRAVKLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>NZ_CP014583.1|WP_024226281.1|4059053_4060613_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDISAPRADLQGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPDSPSFMQDFDELKVKATSIASLLPDAPGKQTKERNTDHFIKRDTTQHLCLHCVPLALFSIQLNAPIGGRGYYPGLRGGGPLTTLIELLEYQGNQQTPLWRKLWLNVMPQDEADLPLPKTFDDLVFPWLAPTRTSELDGAVVTDEQVNKLQAYWGMPRRIRIDFKTTSIGNCDICGRQSDALLGLMSLKNYGVQYVMWRHPLTPRLPLKEGGDFYSVKPQPGGLIWRDWLGLIEVGNSKNNTELPAQVVKLLNASNLKQTRVGLWGFGFDFEDMKVRCWYEHHFPLLLNKKEDLIPKLRLAAQAASHILSLLHRALKEAWFSEKKTTKLDFGFVDIDFWNKTQHRFLRLVRKIEEGQDPDELLSKWQKEMWLFARQDFDDRVFTNPYEPVDLERVMTARKKYFTTSAEKQNANAAREKKQEAAE
>NZ_CP014583.1|WP_069357501.1|4056256_4058956_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKEGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGRPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFLPRVAHPMDIKGYWQKTLVQAQNALTVLPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQAIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEGVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYVTGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATVGLIGKVG
>NZ_CP014583.1|WP_000956458.1|4055911_4056064_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP014583.1|WP_000039850.1|4054912_4055647_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP014583.1|WP_000490402.1|4065219_4066257_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP014583.1|WP_000372106.1|4066508_4067417_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFIHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP014583.1|WP_001090361.1|4067418_4068846_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP014583.1|WP_001173673.1|4068845_4069451_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP014583.1|WP_001246104.1|4069500_4069824_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP014583.1|WP_000517476.1|4070017_4070329_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP014583.1|WP_000246140.1|4070347_4071058_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAVPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP014583.1|WP_001219242.1|4071057_4071537_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP014583.1|WP_000568926.1|4071533_4072583_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQTLLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP014583.1|WP_001295182.1|4072563_4073325_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014583_1	1.1\|926492\|40\|NZ_CP014583\|CRISPRCasFinder	926492-926531	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	1	0.975
NZ_CP014583_5	5.1\|1969759\|54\|NZ_CP014583\|CRISPRCasFinder	1969759-1969812	54	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	165411-165464	1	0.981
NZ_CP014583_8	8.3\|4065078\|32\|NZ_CP014583\|PILER-CR,CRISPRCasFinder,CRT	4065078-4065109	32	MK448454	Streptococcus satellite phage Javan361, complete genome	9192-9223	8	0.75
NZ_CP014583_5	5.1\|1969759\|54\|NZ_CP014583\|CRISPRCasFinder	1969759-1969812	54	NZ_CP048385	Citrobacter freundii strain 62 plasmid p6_C, complete sequence	72431-72484	12	0.778

1. spacer 1.1|926492|40|NZ_CP014583|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 1, identity: 0.975

gcgctgcgggtcattcttgaaattccccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
************************ ***************

2. spacer 5.1|1969759|54|NZ_CP014583|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 1, identity: 0.981

tggcctacacgctgcgattttgtaggccggataagcaaagcgcatccggcattc	CRISPR spacer
tggcctacacgctgcgattttgtaggccggataagcaaagcgcatccggcattg	Protospacer
*****************************************************

3. spacer 8.3|4065078|32|NZ_CP014583|PILER-CR,CRISPRCasFinder,CRT matches to MK448454 (Streptococcus satellite phage Javan361, complete genome) position: , mismatch: 8, identity: 0.75

tccgtttggtccaccaaatgtttgatgcttca	CRISPR spacer
tcttatcaatccaccaaatttttgattcttca	Protospacer
**.  *...********** ****** *****

4. spacer 5.1|1969759|54|NZ_CP014583|CRISPRCasFinder matches to NZ_CP048385 (Citrobacter freundii strain 62 plasmid p6_C, complete sequence) position: , mismatch: 12, identity: 0.778

tggcctacacgct-----gcgattttgtaggccggataagcaaagcgcatccggcattc	CRISPR spacer
-----tacaaattaattcgcggtattgtaggccggataagcaaagcgcatccggcagta	Protospacer
     **** ..*     ***.* ******************************** *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1605 : 10005

Enterobacteria_phage(66.67%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000847298.1\|1605_1935_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_141073548.1\|3324_3957_+\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	2.7e-102	97.6
WP_069356987.1\|4192_7672_+	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	95.3
WP_001449501.1\|7740_8364_+	Ail/Lom family outer membrane beta-barrel protein	A0A1U8QHD6	Enterobacteria_phage	8.7e-69	60.4
WP_069356988.1\|8429_9734_+\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	1.6e-77	98.2
WP_044861268.1\|9735_10005_+\|tail	phage tail fiber C-terminal domain-containing protein	Q9EYE9	Enterobacteria_phage	5.1e-42	94.4

DBSCAN-SWA_2

286953 : 352626

Stx2-converting_phage(28.3%)

tail,transposase,protease,holin,terminase,integrase

attL 299946:300005|attR 351426:352690

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000214712.1\|286953_287157_+	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2
WP_044705919.1\|287240_288653_-	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	6.4e-43	30.1
WP_001120551.1\|290156_290399_+	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_001121225.1\|290993_291644_+	type III secretion system effector NleG7	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_000491541.1\|291868_292744_-	hypothetical protein	A0A0P0ZCT1	Stx2-converting_phage	2.8e-158	97.6
WP_001023386.1\|292884_293154_-\|tail	phage tail fiber C-terminal domain-containing protein	A0A1I9LJT0	Stx_converting_phage	6.0e-43	95.5
WP_071961467.1\|293155_294469_-\|tail	phage tail protein	Q6H9S9	Enterobacteria_phage	1.1e-76	98.9
WP_085948186.1\|294938_296095_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_001063025.1\|298222_298444_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
299946:300005	attL	NA	NA	NA	NA
WP_085948186.1\|299989_301146_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357033.1\|301207_302512_-\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	8.3e-255	99.8
WP_000958380.1\|302508_303072_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_001303046.1\|303361_303727_-	HNH endonuclease	A0A0P0ZCH0	Stx2-converting_phage	2.0e-65	100.0
WP_071961468.1\|303768_303993_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	3.8e-19	90.6
WP_001303878.1\|304074_304389_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_012816791.1\|304915_305101_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000675931.1\|305322_305436_-	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_085948186.1\|305924_307081_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000138558.1\|307616_307889_+	hypothetical protein	NA	NA	NA	NA
WP_024182511.1\|308144_308360_-\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	1.7e-32	97.2
WP_032316861.1\|308799_310650_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.4
WP_000466957.1\|311220_311652_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
WP_000762928.1\|312217_313039_-	antitermination protein	K7P7B9	Enterobacteria_phage	4.1e-82	61.2
WP_001217410.1\|313035_313410_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.1e-33	62.7
WP_001265233.1\|313422_314472_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	3.4e-110	54.3
WP_000191872.1\|314473_314746_-	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_000756596.1\|314867_315212_-	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_000935259.1\|315331_315544_-	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_069357035.1\|316582_316927_-	ead/Ea22-like family protein	NA	NA	NA	NA
WP_077886833.1\|316913_317219_-	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	7.8e-39	79.0
WP_077886881.1\|317215_317491_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.9e-28	73.6
WP_069357037.1\|317523_318240_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.8e-70	60.7
WP_069357038.1\|318269_319010_-	ATP-binding protein	V5UQI5	Shigella_phage	6.4e-119	87.1
WP_069357039.1\|319016_319982_-	hypothetical protein	U5P0A0	Shigella_phage	6.5e-55	60.6
WP_069357040.1\|319962_320484_-	hypothetical protein	NA	NA	NA	NA
WP_071961527.1\|320467_320740_-	helix-turn-helix domain-containing protein	H6WRX5	Salmonella_phage	4.2e-20	63.4
WP_042106857.1\|320865_321258_+	helix-turn-helix domain-containing protein	H6WRX4	Salmonella_phage	1.3e-14	39.6
WP_001022416.1\|321304_321664_-	helix-turn-helix domain-containing protein	A0A222YXG1	Escherichia_phage	7.2e-60	94.1
WP_042106859.1\|321666_321969_-	type II toxin-antitoxin system HigB family toxin	A0A0P0ZE17	Stx2-converting_phage	4.9e-17	42.2
WP_077886834.1\|322244_322397_+	DUF1391 family protein	M4QQ57	Salicola_phage	6.6e-07	53.2
WP_069357042.1\|322408_323047_+	hypothetical protein	NA	NA	NA	NA
WP_001133037.1\|323047_323257_-	hypothetical protein	NA	NA	NA	NA
WP_069357044.1\|323819_324008_+	cell division inhibitor	NA	NA	NA	NA
WP_069357045.1\|324004_324193_+	DUF1482 family protein	NA	NA	NA	NA
WP_069357046.1\|324288_326760_+	exonuclease	A0A192Y6E0	Salmonella_phage	5.7e-55	56.0
WP_042059548.1\|326830_327082_+	excisionase family protein	S4TND0	Salmonella_phage	4.9e-15	50.0
WP_001171554.1\|327614_327995_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|327991_328339_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|328388_329927_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_085948186.1\|330280_331437_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000422741.1\|331666_332092_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|332088_332439_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_032285709.1\|332469_334083_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.5e-181	63.4
WP_085948186.1\|334118_335275_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357662.1\|335336_335468_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	7.9e-17	97.7
WP_069357047.1\|335751_337602_-	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	95.6
WP_000261909.1\|338369_339083_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_069357048.1\|339703_340522_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000090265.1\|340675_341047_-	antitermination protein	Q777W5	Enterobacteria_phage	1.0e-53	84.0
WP_001217436.1\|341036_341408_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_069357049.1\|341420_342470_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	2.1e-107	54.0
WP_069357663.1\|342471_342750_-	hypothetical protein	I6PCV7	Cronobacter_phage	7.4e-12	50.8
WP_001004961.1\|343935_344586_-	hypothetical protein	NA	NA	NA	NA
WP_000887491.1\|344751_344964_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.7e-29	97.1
WP_001278454.1\|345153_345258_-	hypothetical protein	NA	NA	NA	NA
WP_000206794.1\|345373_345958_-	DUF551 domain-containing protein	A0A0P0ZD75	Stx2-converting_phage	5.5e-33	83.5
WP_069357050.1\|346014_346410_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.3e-30	50.7
WP_085948186.1\|347585_348741_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_077886835.1\|348782_349712_-\|integrase	site-specific integrase	Q20GI2	Phage_258-320	2.3e-105	61.1
WP_000005552.1\|349731_349983_-	excisionase family protein	S4TND0	Salmonella_phage	2.2e-15	50.0
WP_097310802.1\|350055_351417_-	exonuclease	A0A192Y6E0	Salmonella_phage	8.0e-59	57.0
WP_085948186.1\|351469_352626_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
351426:352690	attR	NA	NA	NA	NA

DBSCAN-SWA_3

604148 : 699266

102

Enterobacteria_phage(43.55%)

portal,tail,tRNA,protease,holin,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000984512.1\|604148_605030_-\|protease	protease HtpX	NA	NA	NA	NA
WP_001315679.1\|605221_607270_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	6.8e-86	33.5
WP_000431368.1\|607289_607988_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_001043882.1\|608084_608582_-	L-methionine (R)-S-oxide reductase	NA	NA	NA	NA
WP_069357076.1\|608711_609995_+	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_001297532.1\|609963_612597_+	lipid-binding membrane homeostasis protein YebT	NA	NA	NA	NA
WP_024226338.1\|612676_614116_+	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_001295499.1\|614233_614470_+	DUF1480 family protein	NA	NA	NA	NA
WP_001296140.1\|614574_614766_+	YebW family protein	NA	NA	NA	NA
WP_069357077.1\|614766_615423_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	1.5e-55	49.8
WP_000976472.1\|615818_616160_-	YebY family protein	NA	NA	NA	NA
WP_000879280.1\|616172_617045_-	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_000168747.1\|617048_617423_-	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_000916763.1\|617561_617792_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.3e-14	61.8
WP_000011652.1\|617893_618550_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_000944256.1\|618573_619236_+	exodeoxyribonuclease X	Q6UAU3	Klebsiella_phage	2.0e-07	41.6
WP_000936951.1\|619232_621293_-	oligopeptidase B	NA	NA	NA	NA
WP_000024745.1\|621501_622161_-	tellurite resistance TerB family protein	NA	NA	NA	NA
WP_001295500.1\|622487_622844_-	protein YebF	NA	NA	NA	NA
WP_000257738.1\|622910_623201_-	DNA damage-inducible protein YebG	NA	NA	NA	NA
WP_069357078.1\|623334_624513_+	formate-dependent phosphoribosylglycinamide formyltransferase	NA	NA	NA	NA
WP_069357079.1\|624568_625210_-	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_001069467.1\|625246_627058_-	phosphogluconate dehydratase	NA	NA	NA	NA
WP_000301727.1\|627292_628768_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	4.4e-79	37.5
WP_001056694.1\|629105_629975_+	DNA-binding transcriptional regulator HexR	NA	NA	NA	NA
WP_000091148.1\|630102_631545_+	pyruvate kinase	NA	NA	NA	NA
WP_000448381.1\|631677_632649_-	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_024226335.1\|634105_635038_-	zinc ABC transporter substrate-binding protein ZnuA	NA	NA	NA	NA
WP_000202996.1\|635116_635872_+	zinc ABC transporter ATP-binding protein ZnuC	G3M9Y6	Bacillus_virus	1.3e-18	28.3
WP_000571478.1\|635868_636654_+	zinc ABC transporter permease subunit ZnuB	NA	NA	NA	NA
WP_000568519.1\|636802_637813_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	5.6e-09	25.5
WP_000580323.1\|637821_638433_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_072686579.1\|638571_638637_-	hypothetical protein	NA	NA	NA	NA
WP_024226333.1\|638707_639310_+	YebB family permuted papain-like enzyme	NA	NA	NA	NA
WP_001295503.1\|639311_639833_-	crossover junction endodeoxyribonuclease RuvC	G3MA90	Bacillus_virus	2.0e-10	35.1
WP_000907234.1\|639867_640608_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_001300367.1\|640636_641089_-	dihydroneopterin triphosphate diphosphatase	NA	NA	NA	NA
WP_001258662.1\|641206_642979_-\|tRNA	aspartate--tRNA ligase	NA	NA	NA	NA
WP_000891620.1\|643288_643855_+	hydrolase	NA	NA	NA	NA
WP_001261935.1\|644161_644410_+	DinI-like family protein	Q687E4	Enterobacteria_phage	3.5e-37	95.1
WP_122993102.1\|644780_645794_-	M85 family metallopeptidase	NA	NA	NA	NA
WP_122988840.1\|646008_646086_-	hypothetical protein	NA	NA	NA	NA
WP_044861268.1\|646195_646465_-\|tail	phage tail fiber C-terminal domain-containing protein	Q9EYE9	Enterobacteria_phage	5.1e-42	94.4
WP_069356988.1\|646466_647771_-\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	1.6e-77	98.2
WP_001449501.1\|647836_648460_-	Ail/Lom family outer membrane beta-barrel protein	A0A1U8QHD6	Enterobacteria_phage	8.7e-69	60.4
WP_069356987.1\|648528_652008_-	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	95.3
WP_141073548.1\|652243_652876_-\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	2.7e-102	97.6
WP_069357080.1\|652821_653565_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.5e-147	97.2
WP_069357081.1\|653569_654268_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	2.6e-130	97.4
WP_000847298.1\|654267_654597_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_000918266.1\|654593_657239_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	99.7
WP_000532075.1\|657282_657591_-\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	3.0e-54	99.0
WP_069357082.1\|657617_658040_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	1.1e-72	99.3
WP_000235101.1\|658053_658806_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.2e-134	98.8
WP_000682716.1\|658813_659212_-\|tail	tail protein	Q9EYD7	Enterobacteria_phage	5.9e-71	100.0
WP_000974958.1\|659224_659848_-\|tail	phage tail protein	Q8VNN3	Enterobacteria_phage	8.9e-106	100.0
WP_001281348.1\|659850_660132_-	DNA breaking-rejoining protein	Q8VNN4	Enterobacteria_phage	2.1e-46	100.0
WP_001097065.1\|660124_660451_-	DUF2190 family protein	Q9EYD5	Enterobacteria_phage	6.1e-50	100.0
WP_001114424.1\|660538_662563_-\|protease	Clp protease ClpP	S5M7Q8	Escherichia_phage	0.0e+00	99.8
WP_069357083.1\|662507_664010_-\|portal	phage portal protein	S5MW34	Escherichia_phage	1.6e-289	99.6
WP_000102415.1\|664009_664222_-	hypothetical protein	S5MBY8	Escherichia_phage	3.0e-29	98.6
WP_001077625.1\|664218_666342_-\|terminase	phage terminase large subunit family protein	Q9EYD1	Enterobacteria_phage	0.0e+00	100.0
WP_000348565.1\|666338_666815_-	DUF1441 family protein	Q9EYD0	Enterobacteria_phage	2.1e-83	100.0
WP_012816791.1\|667330_667516_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_001092902.1\|668034_668568_-	lysozyme	G9L6J6	Escherichia_phage	2.1e-100	96.6
WP_069357666.1\|668604_669150_-	hypothetical protein	Q08JA0	Stx2-converting_phage	1.1e-46	80.5
WP_000284510.1\|669153_669369_-\|holin	class II holin family protein	G9L6J5	Escherichia_phage	9.0e-34	100.0
WP_001290217.1\|669445_669718_-	DUF826 domain-containing protein	A0A0P0ZC09	Stx2-converting_phage	4.8e-24	100.0
WP_000143457.1\|669758_669938_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	3.7e-25	98.3
WP_069357084.1\|670074_672021_-	DUF1737 domain-containing protein	A0A075M342	Escherichia_Stx1-converting_recombinant_phage	0.0e+00	97.5
WP_000738072.1\|672531_672801_-	Shiga toxin Stx2a subunit B	Q6DWN4	Enterobacteria_phage	1.2e-43	100.0
WP_000649753.1\|672812_673772_-	Shiga toxin Stx2c subunit A	Q776Q3	Enterobacteria_phage	5.6e-176	100.0
WP_000483505.1\|674154_675213_-	site-specific DNA-methyltransferase	A0A0N7KZF8	Stx2-converting_phage	2.9e-205	98.0
WP_000917741.1\|675364_675562_-	hypothetical protein	A0A0P0ZDH6	Stx2-converting_phage	8.0e-29	100.0
WP_001204809.1\|675777_676158_-	antitermination protein Q	S5M7R9	Escherichia_phage	1.4e-66	99.2
WP_001202271.1\|676176_677166_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	8.9e-193	98.2
WP_001065352.1\|677217_677475_-	hypothetical protein	Q8W639	Enterobacteria_phage	1.2e-21	71.1
WP_000203852.1\|677471_678872_-	replicative DNA helicase	Q8W640	Enterobacteria_phage	1.7e-245	92.4
WP_069357085.1\|678868_679747_-	ATP-binding protein	Q8W641	Enterobacteria_phage	6.0e-140	95.6
WP_001247844.1\|679757_680666_-	hypothetical protein	Q8W642	Enterobacteria_phage	2.4e-59	94.0
WP_000621233.1\|680652_680886_-	hypothetical protein	A0A1C9II64	Salmonella_phage	1.6e-12	47.2
WP_000587259.1\|680882_681545_-	ash family protein	Q8W643	Enterobacteria_phage	3.7e-110	92.5
WP_001090254.1\|681653_682361_-	Rha family transcriptional regulator	Q8W645	Enterobacteria_phage	1.6e-114	90.2
WP_000944728.1\|682442_682676_-	helix-turn-helix domain-containing protein	A0A1B5FPK9	Escherichia_phage	1.2e-28	77.0
WP_000789654.1\|682832_683522_+	LexA family transcriptional regulator	A0A1B5FPF4	Escherichia_phage	3.0e-115	88.2
WP_000387836.1\|683670_684372_+	helix-turn-helix domain-containing protein	A0A1B5FPB8	Escherichia_phage	1.5e-37	59.7
WP_000147364.1\|684368_684569_+	hypothetical protein	NA	NA	NA	NA
WP_000553977.1\|684767_684950_+	hypothetical protein	Q8W652	Enterobacteria_phage	2.9e-09	52.7
WP_001365075.1\|684955_685528_+	hypothetical protein	Q8W653	Enterobacteria_phage	5.5e-78	71.3
WP_000720006.1\|685897_686725_+	hypothetical protein	Q8W654	Enterobacteria_phage	1.2e-129	97.5
WP_001484100.1\|686765_687137_+	DUF5406 family protein	Q8W655	Enterobacteria_phage	2.3e-61	95.1
WP_001193437.1\|687328_687583_+	excisionase family protein	Q859D3	Escherichia_coli_phage	3.0e-44	100.0
WP_000063650.1\|687616_688903_+	DUF3596 domain-containing protein	Q20GI2	Phage_258-320	6.9e-254	99.8
WP_069190626.1\|688907_689684_+	DUF72 domain-containing protein	Q859D1	Escherichia_coli_phage	4.7e-72	99.2
WP_000252980.1\|689736_690132_+	MAPEG family protein	NA	NA	NA	NA
WP_000019588.1\|690172_690916_+	carboxy-S-adenosyl-L-methionine synthase CmoA	F5B419	Synechococcus_phage	4.6e-24	30.0
WP_000564725.1\|690912_691884_+\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_069357086.1\|692048_694478_-	trimethylamine N-oxide reductase TorZ	NA	NA	NA	NA
WP_024226209.1\|694502_695603_-	NapC/NirT family cytochrome c	NA	NA	NA	NA
WP_069357087.1\|695990_696737_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_001307851.1\|696750_697317_-	VOC family protein	NA	NA	NA	NA
WP_069357088.1\|697532_699266_+\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	3.4e-86	33.5

DBSCAN-SWA_4

783128 : 812667

Escherichia_phage(44.12%)

transposase,terminase,tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032316817.1\|783128_783458_-\|tail	prophage tail fiber N-terminal domain-containing protein	Q6H9S9	Enterobacteria_phage	6.9e-49	100.0
WP_069357095.1\|783518_783941_-	hypothetical protein	A0A291AWV9	Escherichia_phage	2.6e-32	51.6
WP_032312299.1\|783942_784221_-	hypothetical protein	I6PCV7	Cronobacter_phage	2.2e-11	48.4
WP_000422686.1\|784521_784947_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	2.0e-48	99.0
WP_069356963.1\|784943_785294_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.0e-39	65.5
WP_000080195.1\|785324_786938_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000958398.1\|788756_789320_-\|terminase	terminase small subunit	B6DZ97	Enterobacteria_phage	7.3e-83	94.1
WP_001303046.1\|789609_789975_-	HNH endonuclease	A0A0P0ZCH0	Stx2-converting_phage	2.0e-65	100.0
WP_069357096.1\|790016_790244_+	DUF3950 domain-containing protein	A0A0P0ZCA1	Stx2-converting_phage	1.5e-34	98.7
WP_000736096.1\|790612_790837_-	hypothetical protein	NA	NA	NA	NA
WP_047091958.1\|790922_791108_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.3e-17	98.3
WP_001043239.1\|791329_791548_-	hypothetical protein	Q687G2	Enterobacteria_phage	1.0e-16	93.3
WP_085948186.1\|792037_793193_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000731190.1\|793476_793821_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	3.8e-58	99.1
WP_024165672.1\|793825_794041_-\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	7.7e-33	98.6
WP_069357098.1\|794474_796325_-	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	99.0
WP_069357099.1\|796896_797325_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	6.4e-63	97.1
WP_069357100.1\|797563_798253_-	antiterminator	I6PDF8	Cronobacter_phage	6.3e-52	47.1
WP_069357101.1\|798249_798615_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	7.9e-38	66.7
WP_069357102.1\|798615_799674_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	8.0e-91	48.6
WP_069357667.1\|799675_799954_-	hypothetical protein	I6PCV7	Cronobacter_phage	3.7e-11	50.8
WP_001260977.1\|800089_800347_+	type II toxin-antitoxin system ParD family antitoxin	A0A0N7C055	Escherichia_phage	1.5e-30	86.7
WP_069357103.1\|800352_800652_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2R2Z2Y1	Escherichia_phage	1.1e-50	98.0
WP_069357104.1\|800854_801244_-	hypothetical protein	A0A222YWE8	Escherichia_phage	5.9e-23	52.1
WP_069357105.1\|801339_801696_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	2.3e-58	99.2
WP_069357106.1\|801697_802159_-	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	6.2e-64	65.2
WP_000699805.1\|802145_802379_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	3.6e-12	50.7
WP_077886885.1\|802375_802657_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	3.6e-30	73.6
WP_069357108.1\|802689_803457_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	4.3e-78	67.3
WP_157917783.1\|803491_804034_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.7e-84	98.0
WP_069357109.1\|803945_804986_-	phage replisome organizer	A0A0U2RT81	Escherichia_phage	3.7e-104	93.4
WP_069357110.1\|805057_805483_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_069357111.1\|805466_805739_-	helix-turn-helix domain-containing protein	H6WRX5	Salmonella_phage	5.0e-13	50.0
WP_069357112.1\|805848_806250_+	helix-turn-helix domain-containing protein	A0A1B5FPF4	Escherichia_phage	1.3e-12	53.0
WP_000100899.1\|806277_806469_+	hypothetical protein	NA	NA	NA	NA
WP_000936798.1\|806468_806756_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_021523420.1\|807030_807183_+	DUF1391 family protein	M4QQ57	Salicola_phage	1.7e-07	53.2
WP_172907136.1\|807194_807554_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.7e-06	51.0
WP_069357115.1\|808282_808471_+	cell division inhibitor	NA	NA	NA	NA
WP_000199478.1\|808467_808656_+	DUF1482 family protein	NA	NA	NA	NA
WP_069357116.1\|808748_811187_+	exonuclease	V5UQJ3	Shigella_phage	1.3e-112	45.1
WP_069357117.1\|811248_811455_+	excisionase	NA	NA	NA	NA
WP_085948186.1\|811511_812667_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

957495 : 1010451

Enterobacteria_phage(37.5%)

tail,portal,head,capsid,transposase,protease,holin,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000003671.1\|957495_958083_-\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA
WP_001186424.1\|958079_958787_-	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_069357138.1\|958805_960599_-	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_001058323.1\|960595_961714_-	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_012817749.1\|962829_963582_+	type III effector	NA	NA	NA	NA
WP_001023445.1\|963706_963976_-\|tail	phage tail fiber C-terminal domain-containing protein	Q687E5	Enterobacteria_phage	2.1e-43	97.8
WP_085948186.1\|964187_965343_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357139.1\|966622_967246_-	Ail/Lom family outer membrane beta-barrel protein	A0A1U8QHD6	Enterobacteria_phage	2.3e-69	61.8
WP_069357140.1\|967313_970790_-	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	96.5
WP_158707114.1\|971036_971669_-\|tail	tail assembly protein	A0A0P0ZDX8	Stx2-converting_phage	1.8e-101	94.7
WP_069357142.1\|971614_972358_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	3.3e-147	97.6
WP_069357143.1\|972368_973067_-\|tail	phage minor tail protein L	Q6H9T5	Enterobacteria_phage	4.6e-127	95.7
WP_032211147.1\|973066_973396_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	5.2e-57	97.2
WP_069357144.1\|973392_976008_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	81.7
WP_071961477.1\|975988_976402_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	1.9e-43	84.2
WP_069357145.1\|976428_976851_-\|tail	phage minor tail protein G	S5MQJ3	Escherichia_phage	2.6e-64	90.7
WP_069357146.1\|976866_977616_-\|tail	phage tail protein	S5M7Q5	Escherichia_phage	9.6e-131	95.2
WP_042106356.1\|977623_978019_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	1.7e-57	80.9
WP_069357147.1\|978015_978591_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	2.9e-50	58.3
WP_069357148.1\|978606_978960_-\|tail	phage tail protein	A0A0K2FJB7	Enterobacteria_phage	1.9e-41	70.1
WP_069357149.1\|978952_979336_-	DNA-packaging protein FI	NA	NA	NA	NA
WP_069357150.1\|979387_980416_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.3e-114	62.2
WP_069357151.1\|980473_980821_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.2e-23	53.3
WP_069357152.1\|980857_982363_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.0e-99	53.7
WP_069357153.1\|982352_983945_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	1.8e-182	60.5
WP_000259002.1\|983941_984148_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_069357154.1\|984131_986060_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.4e-263	66.5
WP_000235436.1\|986031_986541_-\|terminase	terminase small subunit	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_032176216.1\|986942_987167_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.2e-21	90.9
WP_001302717.1\|987248_987563_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_123056124.1\|988047_988233_-	hypothetical protein	A0A0P0ZCT3	Stx2-converting_phage	1.5e-13	88.5
WP_000459343.1\|988454_988592_-	hypothetical protein	Q687G2	Enterobacteria_phage	2.2e-17	95.6
WP_000992152.1\|988751_989285_-	lysozyme	B6DZ92	Enterobacteria_phage	6.2e-100	96.0
WP_000731190.1\|989335_989680_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	3.8e-58	99.1
WP_000284518.1\|989684_989900_-\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	2.0e-33	100.0
WP_001290231.1\|989976_990249_-	DUF826 domain-containing protein	A0A0P0ZBB8	Stx2-converting_phage	2.2e-21	100.0
WP_000143462.1\|990289_990469_-	DUF1378 family protein	A0A0P0ZCJ7	Stx2-converting_phage	3.7e-25	100.0
WP_032212763.1\|990604_992542_-	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	0.0e+00	96.7
WP_000466957.1\|993020_993452_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
WP_097310795.1\|993897_994611_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_069357156.1\|994747_994945_-	TrmB family transcriptional regulator	Q9MC00	Enterobacteria_phage	1.0e-28	96.9
WP_069357157.1\|995168_995723_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	2.1e-66	68.0
WP_069357158.1\|995731_996091_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	6.2e-35	60.9
WP_069357159.1\|996103_997153_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.6e-115	57.8
WP_069357667.1\|997154_997433_-	hypothetical protein	I6PCV7	Cronobacter_phage	3.7e-11	50.8
WP_001260977.1\|997568_997826_+	type II toxin-antitoxin system ParD family antitoxin	A0A0N7C055	Escherichia_phage	1.5e-30	86.7
WP_069357103.1\|997831_998131_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2R2Z2Y1	Escherichia_phage	1.1e-50	98.0
WP_077886843.1\|998335_998836_-	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	9.8e-23	64.8
WP_001002669.1\|998966_999278_-	hypothetical protein	A0A222YY67	Escherichia_phage	1.2e-50	82.5
WP_069357160.1\|999270_999525_-	hypothetical protein	A0A0U2RK51	Escherichia_phage	6.7e-44	98.8
WP_179985401.1\|999521_1000169_-	ead/Ea22-like family protein	A0A0U2QW67	Escherichia_phage	4.2e-90	79.6
WP_069357161.1\|1000155_1000461_-	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	9.8e-50	96.0
WP_069357162.1\|1000457_1000880_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	9.4e-67	93.6
WP_000693883.1\|1002051_1002477_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000747951.1\|1002460_1002703_-	hypothetical protein	H9C161	Pectobacterium_phage	4.8e-07	55.8
WP_001397087.1\|1003094_1003433_+	peptidase S24-like family protein	H9C160	Pectobacterium_phage	2.5e-06	30.7
WP_172907137.1\|1003778_1004078_+	hypothetical protein	NA	NA	NA	NA
WP_045903484.1\|1004149_1004368_+	hypothetical protein	NA	NA	NA	NA
WP_069357164.1\|1004390_1004798_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	1.0e-09	40.9
WP_000449192.1\|1005568_1005757_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001090200.1\|1005753_1005945_+	DUF1482 family protein	NA	NA	NA	NA
WP_085948186.1\|1006385_1007541_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_085948186.1\|1008435_1009592_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000375138.1\|1009791_1010451_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	5.2e-48	54.9

DBSCAN-SWA_6

1236580 : 1253347

Escherichia_phage(27.78%)

transposase,tail,integrase,holin

attL 1233927:1233941|attR 1253421:1253435

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1233927:1233941	attL	NA	NA	NA	NA
WP_085948186.1\|1236580_1237736_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357675.1\|1239755_1241069_-\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	1.4e-76	97.0
WP_000284515.1\|1241293_1241509_-\|holin	class II holin family protein	A0A0P0ZC45	Stx2-converting_phage	2.0e-33	100.0
WP_033816266.1\|1241651_1242050_+	hypothetical protein	H6WZJ8	Escherichia_phage	6.9e-11	83.3
WP_000499454.1\|1242130_1242289_-	DUF3927 family protein	NA	NA	NA	NA
WP_001302581.1\|1242374_1243118_-	hypothetical protein	NA	NA	NA	NA
WP_001235472.1\|1243370_1243994_-	antitermination protein	K7PM87	Enterobacteria_phage	2.2e-112	98.1
WP_053884950.1\|1243990_1244656_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	1.5e-130	99.1
WP_032205168.1\|1244808_1244991_+	hypothetical protein	A0A1I9LJN0	Stx_converting_phage	7.2e-24	98.3
WP_032205166.1\|1244987_1245668_+	YqaJ viral recombinase family protein	B6DZ61	Enterobacteria_phage	1.5e-130	97.8
WP_000682294.1\|1245664_1245826_+	DUF1317 family protein	A0A0N7CHV0	Escherichia_phage	7.7e-22	96.0
WP_000129285.1\|1245818_1246376_+	phage N-6-adenine-methyltransferase	E5AGF8	Erwinia_phage	2.0e-61	62.3
WP_000188870.1\|1246452_1246668_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.0e-32	100.0
WP_000763378.1\|1246766_1246988_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	8.4e-35	97.3
WP_069357193.1\|1246984_1247686_+	ead/Ea22-like family protein	A0A0U2QW67	Escherichia_phage	1.6e-50	55.3
WP_097310820.1\|1247852_1249021_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	4.3e-170	91.1
WP_069357195.1\|1249067_1249358_+	hypothetical protein	Q9MCR3	Enterobacteria_phage	2.0e-20	94.5
WP_069357196.1\|1249488_1250187_+	DUF1311 domain-containing protein	J9Q6K3	Salmonella_phage	2.1e-100	81.5
WP_001303965.1\|1250423_1250723_+	hypothetical protein	G9L655	Escherichia_phage	2.4e-53	100.0
WP_085948186.1\|1250861_1252018_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_071961483.1\|1252056_1252299_+	excisionase	Q77WA4	Escherichia_phage	1.6e-34	100.0
WP_069357197.1\|1252276_1253347_+\|integrase	tyrosine-type recombinase/integrase	Q9MCR4	Enterobacteria_phage	1.5e-201	99.7
1253421:1253435	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1712748 : 1777061

Staphylococcus_phage(16.67%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000131044.1\|1712748_1714782_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	3.4e-21	27.4
WP_001299022.1\|1714910_1715498_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_000089075.1\|1715511_1716984_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_001159102.1\|1716997_1718668_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	4.7e-61	31.2
WP_024230919.1\|1718880_1719549_+	membrane protein	NA	NA	NA	NA
WP_001364640.1\|1719791_1720487_-	lactate utilization protein C	NA	NA	NA	NA
WP_000023907.1\|1720479_1721907_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_001102129.1\|1721917_1722637_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_000339589.1\|1723155_1724010_-	DNA-binding transcriptional regulator RclR	NA	NA	NA	NA
WP_000474077.1\|1725669_1725906_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_069357242.1\|1725917_1726511_+	reactive chlorine species resistance protein RclC	NA	NA	NA	NA
WP_001299025.1\|1726670_1727540_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.3e-53	41.7
WP_000621018.1\|1727788_1728646_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_024230918.1\|1728766_1733020_-	intimin-like adhesin FdeC	NA	NA	NA	NA
WP_001174461.1\|1733585_1734437_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-47	40.7
WP_069357243.1\|1734463_1735453_+	aldo/keto reductase	NA	NA	NA	NA
WP_024226490.1\|1735484_1736378_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000662258.1\|1736840_1736942_+	hypothetical protein	NA	NA	NA	NA
WP_000803999.1\|1737305_1737569_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_024226489.1\|1737568_1737709_+	50S ribosomal protein L36	NA	NA	NA	NA
WP_001147277.1\|1737743_1737971_-	hypothetical protein	NA	NA	NA	NA
WP_001296902.1\|1738793_1739336_+	ECP biosynthesis operon DNA-binding transcriptional regulator EcpR	NA	NA	NA	NA
WP_000730974.1\|1739410_1739998_+	common pilus major fimbrillin subunit EcpA	NA	NA	NA	NA
WP_000716398.1\|1740055_1740724_+	fimbrial chaperone EcpB	NA	NA	NA	NA
WP_069357244.1\|1740749_1743275_+	fimbrial usher EcpC	NA	NA	NA	NA
WP_069357245.1\|1743264_1744908_+	fimbrial adhesin EcpD	NA	NA	NA	NA
WP_069357246.1\|1744876_1745587_+	fimbrial chaperone EcpE	NA	NA	NA	NA
WP_001303809.1\|1745899_1746229_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_085948186.1\|1746461_1747618_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000893278.1\|1748633_1749887_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	9.8e-96	47.2
WP_001285288.1\|1749898_1751002_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_069357247.1\|1751289_1752345_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	2.9e-117	60.6
WP_000174677.1\|1752383_1752785_-	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_000189543.1\|1752842_1754087_-	esterase FrsA	NA	NA	NA	NA
WP_001291990.1\|1754178_1754637_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_001293016.1\|1754897_1756355_+	cytosol nonspecific dipeptidase	NA	NA	NA	NA
WP_071961488.1\|1756411_1757002_-	peptide chain release factor H	NA	NA	NA	NA
WP_025380665.1\|1757055_1757481_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	5.8e-48	97.9
WP_069356963.1\|1757477_1757828_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.0e-39	65.5
WP_000080195.1\|1757858_1759472_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_071961489.1\|1760949_1761402_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001226164.1\|1761398_1762454_-	DNA polymerase IV	NA	NA	NA	NA
WP_000207568.1\|1762524_1763310_-	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
WP_001365368.1\|1763254_1764622_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_000598760.1\|1764726_1765005_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_001030484.1\|1764997_1765354_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_000543899.1\|1765410_1766184_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.2e-19	37.7
WP_000729704.1\|1766369_1766630_+	type II toxin-antitoxin system antitoxin DinJ	NA	NA	NA	NA
WP_000615979.1\|1766632_1766911_+	type II toxin-antitoxin system mRNA interferase toxin YafQ	NA	NA	NA	NA
WP_001225679.1\|1767066_1767807_+	murein L,D-transpeptidase	NA	NA	NA	NA
WP_001365365.1\|1767777_1768545_-	class II glutamine amidotransferase	NA	NA	NA	NA
WP_000284050.1\|1768750_1769329_-	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
WP_069357249.1\|1769568_1772013_+	acyl-CoA dehydrogenase FadE	NA	NA	NA	NA
WP_000532698.1\|1772055_1772529_-	C-lysozyme inhibitor	NA	NA	NA	NA
WP_001118027.1\|1772682_1773453_+	2-oxoglutaramate amidase	NA	NA	NA	NA
WP_069357250.1\|1773494_1774631_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_001077737.1\|1775099_1775477_-	hypothetical protein	NA	NA	NA	NA
WP_176551833.1\|1775476_1775755_-	type IV secretion protein Rhs	NA	NA	NA	NA
WP_069357251.1\|1775924_1777061_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2037047 : 2109590

Enterobacteria_phage(38.46%)

tail,tRNA,head,transposase,holin,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069357277.1\|2037047_2037734_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_001303782.1\|2038133_2038274_-	hypothetical protein	NA	NA	NA	NA
WP_001194358.1\|2038369_2039086_+	two-component system response regulator ArcA	NA	NA	NA	NA
WP_000920343.1\|2039145_2040498_-	cell envelope integrity protein CreD	NA	NA	NA	NA
WP_069357278.1\|2040555_2041980_-	two-component system sensor histidine kinase CreC	Q8QKV7	Ectocarpus_siliculosus_virus	2.7e-09	20.4
WP_069357279.1\|2041995_2042676_-	two-component system response regulator CreB	W8CYM9	Bacillus_phage	1.8e-27	34.7
WP_000875487.1\|2042688_2043162_-	protein CreA	NA	NA	NA	NA
WP_000371666.1\|2043372_2044242_+	MDR efflux pump AcrAB transcriptional activator RobA	NA	NA	NA	NA
WP_000942344.1\|2044238_2044886_-	2,3-diphosphoglycerate-dependent phosphoglycerate mutase GpmB	NA	NA	NA	NA
WP_024177800.1\|2044937_2045450_+	inosine/xanthosine triphosphatase	NA	NA	NA	NA
WP_000068679.1\|2045596_2045923_-	trp operon repressor	NA	NA	NA	NA
WP_000409458.1\|2046012_2047950_-	murein transglycosylase	A0A1P8CWQ1	Bacillus_phage	2.3e-11	35.7
WP_000046749.1\|2048160_2049828_+	energy-dependent translational throttle protein EttA	A0A1V0SKJ1	Klosneuvirus	3.7e-42	26.4
WP_069357280.1\|2050097_2051366_-	multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR	A0A0C5K935	Enterococcus_phage	3.3e-83	42.7
WP_001029697.1\|2051386_2052769_-	DNA repair protein RadA	NA	NA	NA	NA
WP_001132955.1\|2052817_2053786_-	phosphoserine phosphatase	NA	NA	NA	NA
WP_000124615.1\|2053891_2054536_+	YtjB family periplasmic protein	NA	NA	NA	NA
WP_000105889.1\|2054563_2055580_+	lipoate--protein ligase LplA	NA	NA	NA	NA
WP_000566153.1\|2055611_2055761_+	hypothetical protein	NA	NA	NA	NA
WP_000224877.1\|2056035_2056755_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_000816471.1\|2056834_2058058_-	phosphopentomutase	NA	NA	NA	NA
WP_000477811.1\|2058109_2059432_-	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	2.3e-79	39.8
WP_069357281.1\|2059558_2060326_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_069357282.1\|2060583_2062134_+	YjjI family glycine radical enzyme	NA	NA	NA	NA
WP_001088381.1\|2062105_2062969_+	YjjW family glycine radical enzyme activase	NA	NA	NA	NA
WP_000563078.1\|2063081_2063864_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_001299187.1\|2063860_2064934_-	patatin family protein	NA	NA	NA	NA
WP_000490275.1\|2065055_2065217_-	DUF1328 domain-containing protein	A0A0N7CBR2	Salmonella_phage	1.8e-10	64.2
WP_024225983.1\|2065343_2065949_-	molecular chaperone OsmY	NA	NA	NA	NA
WP_000202564.1\|2066341_2067928_-	peptide chain release factor 3	D0R0F5	Streptococcus_phage	5.3e-30	24.9
WP_001217539.1\|2068147_2068396_+	DinI-like family protein	A5LH55	Enterobacteria_phage	1.1e-38	100.0
WP_001372053.1\|2068822_2068936_+	hypothetical protein	A0A1C9IHU6	Salmonella_phage	1.4e-06	77.8
WP_000836769.1\|2069004_2069238_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	6.4e-33	88.3
WP_060616940.1\|2069617_2070208_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	4.7e-24	38.3
WP_085948186.1\|2070764_2071920_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357283.1\|2072147_2072966_-\|tail	tail fiber protein	K7PHC9	Enterobacteria_phage	8.5e-48	66.1
WP_069357284.1\|2073065_2073809_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	4.9e-151	98.4
WP_001152535.1\|2073814_2074513_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.8e-131	98.3
WP_000847347.1\|2074512_2074842_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	3.6e-58	99.1
WP_044782212.1\|2074838_2077400_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	97.3
WP_024226131.1\|2077392_2077827_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	5.8e-64	98.3
WP_000479169.1\|2077808_2078231_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.1e-70	96.4
WP_024229183.1\|2078246_2078987_-\|tail	phage tail protein	A0A2I6TC77	Escherichia_phage	1.5e-128	95.9
WP_069357285.1\|2078994_2079390_-\|tail	phage tail protein	A0A0K2FIF4	Enterobacteria_phage	2.2e-70	99.2
WP_069357286.1\|2079386_2079965_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	8.6e-79	96.9
WP_000753007.1\|2079976_2080330_-\|head,tail	head-tail joining protein	A0A0K2FJB7	Enterobacteria_phage	4.4e-62	99.1
WP_000158906.1\|2080341_2080740_-	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_000198149.1\|2081229_2081436_-	gpW family protein	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_069357287.1\|2081432_2083358_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.5
WP_000422741.1\|2083766_2084192_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|2084188_2084539_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_032285709.1\|2084569_2086183_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.5e-181	63.4
WP_032154345.1\|2086806_2087001_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	3.7e-26	95.2
WP_000548594.1\|2087251_2087458_-	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	2.6e-22	80.9
WP_001019207.1\|2087753_2087927_-	addiction module toxin, GnsA/GnsB family	NA	NA	NA	NA
WP_001443523.1\|2088099_2088255_-	hypothetical protein	NA	NA	NA	NA
WP_071961531.1\|2088402_2088591_-	cold-shock protein	NA	NA	NA	NA
WP_000066495.1\|2088601_2088814_-	cold shock protein CspI	A0A1W6JNX5	Morganella_phage	1.2e-22	74.3
WP_001071778.1\|2089177_2089675_-	DUF2514 domain-containing protein	NA	NA	NA	NA
WP_001101173.1\|2089671_2090205_-	lysozyme	K7PLY1	Enterobacteria_phage	1.4e-96	93.8
WP_001557934.1\|2090318_2090579_+	hypothetical protein	NA	NA	NA	NA
WP_000189900.1\|2090526_2091078_-	YdfR family protein	Q08JA0	Stx2-converting_phage	1.0e-36	51.1
WP_000839581.1\|2091082_2091298_-\|holin	class II holin family protein	A5LH82	Enterobacteria_phage	7.9e-30	90.1
WP_000066482.1\|2092050_2092266_-	cold shock-like protein CspB	A0A1W6JNX5	Morganella_phage	2.6e-25	76.5
WP_001557932.1\|2092566_2092779_+	cold shock-like protein CspF	NA	NA	NA	NA
WP_122993159.1\|2092833_2092923_+	hypothetical protein	NA	NA	NA	NA
WP_000203370.1\|2093548_2093734_+	hypothetical protein	NA	NA	NA	NA
WP_001557930.1\|2094894_2095647_-	antitermination protein	K7PGU5	Enterobacteria_phage	2.4e-134	97.2
WP_016235097.1\|2095660_2096650_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	8.1e-194	98.8
WP_001061427.1\|2096657_2097500_-	KilA-N domain-containing protein	S5MC03	Escherichia_phage	1.1e-138	91.5
WP_000767113.1\|2097519_2097909_-	RusA family crossover junction endodeoxyribonuclease	A0A0P0ZD39	Stx2-converting_phage	7.1e-69	100.0
WP_069357288.1\|2097905_2098559_-	phage N-6-adenine-methyltransferase	K7PGU4	Enterobacteria_phage	5.2e-125	97.2
WP_072147590.1\|2098558_2099053_-	PerC family transcriptional regulator	A0A291AWV6	Escherichia_phage	4.3e-87	98.1
WP_069357289.1\|2099049_2099868_-	helix-turn-helix domain-containing protein	A0A291AWW0	Escherichia_phage	5.2e-122	98.5
WP_000933943.1\|2099864_2100101_-	hypothetical protein	A0A291AX25	Escherichia_phage	2.7e-39	98.7
WP_050922078.1\|2100093_2100930_-	ash family protein	A0A291AWU3	Escherichia_phage	4.8e-147	96.8
WP_000515860.1\|2100926_2101478_-	hypothetical protein	Q8SBF4	Shigella_phage	7.6e-101	100.0
WP_000649477.1\|2101521_2101722_-	helix-turn-helix domain-containing protein	U5P445	Shigella_phage	7.9e-32	100.0
WP_000859462.1\|2101812_2102487_+	LexA family transcriptional repressor	Q8SBF6	Shigella_phage	1.2e-132	100.0
WP_000500990.1\|2102689_2103202_-	hypothetical protein	NA	NA	NA	NA
WP_024226706.1\|2103670_2104033_+	hypothetical protein	U5P4J6	Shigella_phage	1.3e-56	94.2
WP_024226707.1\|2104098_2104923_+	DUF2303 family protein	U5P439	Shigella_phage	3.0e-149	99.6
WP_000008177.1\|2105050_2105587_+	5'-deoxynucleotidase	A5LH62	Enterobacteria_phage	9.0e-99	98.3
WP_024226708.1\|2105951_2106836_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_024226709.1\|2107006_2108143_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_106898618.1\|2108422_2109590_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	4.3e-170	91.1

DBSCAN-SWA_9

2134627 : 2200625

Shigella_phage(20.0%)

transposase,integrase

attL 2134585:2134644|attR 2199093:2200356

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2134585:2134644	attL	NA	NA	NA	NA
WP_085948186.1\|2134627_2135784_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_120795393.1\|2136873_2136957_+	iraD leader peptide IdlP	NA	NA	NA	NA
WP_069357296.1\|2136953_2137346_+	anti-adapter protein IraD	NA	NA	NA	NA
WP_000340757.1\|2137338_2138250_-	hypochlorite stress DNA-binding transcriptional regulator HypT	NA	NA	NA	NA
WP_000568417.1\|2138314_2139487_-	beta-aspartyl-peptidase	NA	NA	NA	NA
WP_000211971.1\|2139499_2139961_-	hypothetical protein	NA	NA	NA	NA
WP_001295597.1\|2139957_2140641_-	nucleoside recognition pore and gate family inner membrane transporter	NA	NA	NA	NA
WP_001151854.1\|2140891_2141446_+	RNA 2'-phosphotransferase	A0A2R2ZGT8	Clostridioides_phage	2.7e-37	45.6
WP_001141192.1\|2141458_2142637_-	MFS transporter	NA	NA	NA	NA
WP_001298932.1\|2142704_2143565_-	YjiK family protein	NA	NA	NA	NA
WP_000657676.1\|2143629_2143887_-	DUF3343 domain-containing protein	NA	NA	NA	NA
WP_000222495.1\|2143883_2144651_-	hypothetical protein	NA	NA	NA	NA
WP_024226720.1\|2144660_2145812_-	2-hydroxyacyl-CoA dehydratase subunit D	NA	NA	NA	NA
WP_001037377.1\|2145927_2147208_-	DUF445 domain-containing protein	NA	NA	NA	NA
WP_001137015.1\|2147248_2148481_-	multidrug efflux MFS transporter MdtM	NA	NA	NA	NA
WP_000181139.1\|2148958_2149915_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	1.1e-59	50.8
WP_000394276.1\|2151746_2151911_+	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_001324160.1\|2154881_2155838_-	GTPase	NA	NA	NA	NA
WP_000467859.1\|2155848_2156052_-	YbdD/YjiX family protein	NA	NA	NA	NA
WP_001298933.1\|2156101_2158252_-	pyruvate/proton symporter BtsT	NA	NA	NA	NA
WP_001175455.1\|2158644_2159157_-	4-hydroxyphenylacetate 3-monooxygenase reductase subunit	NA	NA	NA	NA
WP_000801478.1\|2159174_2160737_-	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component	NA	NA	NA	NA
WP_000332891.1\|2160987_2161878_-	4-hydroxyphenylacetate catabolism regulatory protein HpaA	NA	NA	NA	NA
WP_001285769.1\|2161887_2163264_-	4-hydroxyphenylacetate permease	NA	NA	NA	NA
WP_000431706.1\|2163438_2164227_-	4-hydroxy-2-oxoheptanedioate aldolase	NA	NA	NA	NA
WP_069357297.1\|2164237_2165041_-	2-oxo-hepta-3-ene-1,7-dioic acid hydratase	NA	NA	NA	NA
WP_001119865.1\|2165151_2165532_-	5-carboxymethyl-2-hydroxymuconate Delta-isomerase	NA	NA	NA	NA
WP_000516970.1\|2165541_2166393_-	3,4-dihydroxyphenylacetate 2,3-dioxygenase	NA	NA	NA	NA
WP_024226716.1\|2166394_2167861_-	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000679092.1\|2167857_2169147_-	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase	NA	NA	NA	NA
WP_000543915.1\|2169418_2169865_+	homoprotocatechuate degradation operon regulator HpaR	NA	NA	NA	NA
WP_000919569.1\|2169983_2171648_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	6.2e-13	39.6
WP_024226714.1\|2171696_2173058_-	MFS transporter	NA	NA	NA	NA
WP_000091570.1\|2173272_2174187_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000106030.1\|2174325_2175348_+	L-galactonate oxidoreductase	A0A2K9L7I1	Tupanvirus	2.7e-11	26.3
WP_001292661.1\|2175487_2177779_-	phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase	NA	NA	NA	NA
WP_001308243.1\|2178032_2178527_-	DUF2501 domain-containing protein	NA	NA	NA	NA
WP_000799911.1\|2178575_2179313_-	DNA replication protein DnaC	V5UQI5	Shigella_phage	7.6e-64	50.8
WP_000098818.1\|2179315_2179855_-	primosomal protein DnaT	T1SA92	Salmonella_phage	2.9e-28	62.8
WP_000538183.1\|2179961_2180435_-	threonine/serine exporter	NA	NA	NA	NA
WP_069357298.1\|2180425_2181196_-	threonine/serine exporter ThrE family protein	NA	NA	NA	NA
WP_000936630.1\|2181814_2182540_+	response regulator transcription factor	NA	NA	NA	NA
WP_069357299.1\|2182497_2183175_+	DNA-binding transcriptional activator BglJ	NA	NA	NA	NA
WP_000331559.1\|2183212_2184001_-	siderophore-iron reductase FhuF	NA	NA	NA	NA
WP_001403902.1\|2184141_2184378_+	DUF1435 domain-containing protein	NA	NA	NA	NA
WP_001272319.1\|2184804_2185836_-	16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC	NA	NA	NA	NA
WP_000204019.1\|2185938_2186376_+	DNA polymerase III subunit psi	NA	NA	NA	NA
WP_001092458.1\|2186320_2186767_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_000870697.1\|2186781_2187459_+	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_001218281.1\|2187843_2189067_+\|integrase	site-specific integrase	A5LH57	Enterobacteria_phage	9.5e-237	99.0
WP_069357300.1\|2189149_2190331_-	MFS transporter	NA	NA	NA	NA
WP_106898618.1\|2190324_2191493_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	4.3e-170	91.1
WP_069357301.1\|2191549_2191885_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	5.9e-40	66.1
WP_000422741.1\|2191881_2192307_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_097310792.1\|2192853_2193843_-	restriction endonuclease	NA	NA	NA	NA
WP_069357303.1\|2193971_2197487_-	ATP-binding protein	NA	NA	NA	NA
WP_085948186.1\|2197952_2199108_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357304.1\|2199133_2199457_-	hypothetical protein	NA	NA	NA	NA
WP_085948186.1\|2199468_2200625_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
2199093:2200356	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2519237 : 2530878

Enterobacteria_phage(33.33%)

transposase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217541.1\|2519237_2519486_+	DinI-like family protein	A5LH55	Enterobacteria_phage	3.1e-38	98.8
WP_069357342.1\|2519646_2520288_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	1.4e-106	99.1
WP_072140863.1\|2520369_2520999_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.4e-79	93.5
WP_069357343.1\|2521071_2521653_-	T3SS effector NleG family protein	H6WZN1	Escherichia_phage	1.1e-46	53.2
WP_001023420.1\|2521765_2522035_-\|tail	phage tail fiber C-terminal domain-containing protein	H6WZN0	Escherichia_phage	3.8e-45	100.0
WP_000268987.1\|2522036_2523350_-\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	4.8e-77	98.6
WP_001427270.1\|2523414_2524014_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	1.7e-109	98.5
WP_085948186.1\|2524982_2526139_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_106898619.1\|2526177_2526942_+	DUF2303 family protein	Q8SBF9	Shigella_phage	2.8e-133	98.8
WP_000008177.1\|2527070_2527607_+	5'-deoxynucleotidase	A5LH62	Enterobacteria_phage	9.0e-99	98.3
WP_021567715.1\|2527597_2527948_+	hypothetical protein	A0A0P0ZBF8	Stx2-converting_phage	6.6e-58	96.6
WP_021567714.1\|2527944_2528430_+	class I SAM-dependent methyltransferase	H9C170	Pectobacterium_phage	3.7e-67	76.5
WP_071961501.1\|2528426_2529536_+	ead/Ea22-like family protein	G9L6G3	Escherichia_phage	1.8e-77	92.1
WP_069357345.1\|2529535_2530108_+	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	6.7e-108	97.9
WP_001093909.1\|2530144_2530417_+	pyocin activator PrtN family protein	S5MQM5	Escherichia_phage	5.9e-38	86.7
WP_000549966.1\|2530443_2530878_-	type II toxin-antitoxin system YafO family toxin	A0A0S2SYH1	Pseudomonas_phage	5.2e-36	51.0

DBSCAN-SWA_11

3758536 : 3818452

Stx2-converting_phage(30.0%)

transposase,protease,integrase

attL 3775171:3775187|attR 3818656:3818672

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001034520.1\|3758536_3763105_+\|protease	lipoprotein metalloprotease SslE	NA	NA	NA	NA
WP_001297673.1\|3763252_3764062_+	prepilin peptidase PppA	NA	NA	NA	NA
WP_001324279.1\|3764127_3764538_+	type II secretion system pilot lipoprotein GspS-beta	NA	NA	NA	NA
WP_000135068.1\|3764555_3765515_+	type II secretion system protein GspC	NA	NA	NA	NA
WP_069357458.1\|3765544_3767605_+	type II secretion system secretin GspD	NA	NA	NA	NA
WP_000249348.1\|3767604_3769098_+	type II secretion system ATPase GspE	NA	NA	NA	NA
WP_001173448.1\|3769097_3770321_+	type II secretion system inner membrane protein GspF	NA	NA	NA	NA
WP_001087296.1\|3770337_3770793_+	type II secretion system major pseudopilin GspG	NA	NA	NA	NA
WP_001115140.1\|3770796_3771360_+	type II secretion system minor pseudopilin GspH	NA	NA	NA	NA
WP_000820106.1\|3771356_3771728_+	type II secretion system minor pseudopilin GspI	NA	NA	NA	NA
WP_001255034.1\|3771724_3772324_+	type II secretion system minor pseudopilin GspJ	NA	NA	NA	NA
WP_000633205.1\|3772326_3773304_+	type II secretion system minor pseudopilin GspK	NA	NA	NA	NA
WP_024226662.1\|3773300_3774479_+	type II secretion system protein GspL	NA	NA	NA	NA
WP_000942793.1\|3774480_3775017_+	GspM family type II secretion system protein YghD	NA	NA	NA	NA
3775171:3775187	attL	NA	NA	NA	NA
WP_069357459.1\|3775346_3776189_-	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_069357460.1\|3776273_3776465_-	DUF957 domain-containing protein	NA	NA	NA	NA
WP_069357461.1\|3776837_3777215_-	toxin	NA	NA	NA	NA
WP_069357462.1\|3777304_3777673_-	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
WP_069357463.1\|3777747_3777969_-	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
WP_069357464.1\|3778031_3778508_-	RadC family protein	NA	NA	NA	NA
WP_069357465.1\|3778523_3779009_-	antirestriction protein	A9J566	Pseudomonas_phage	2.0e-12	31.0
WP_085947772.1\|3779167_3780381_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.3e-100	57.1
WP_001121622.1\|3782064_3783714_+	type III secretion system effector EspL2	NA	NA	NA	NA
WP_069357327.1\|3784322_3785312_+	type III secretion system effector arginine glycosyltransferase NleB	Q8HAB2	Salmonella_phage	3.7e-98	58.5
WP_000609742.1\|3785360_3786035_+	type III secretion system effector cysteine methyltransferase NleE	NA	NA	NA	NA
WP_000422686.1\|3798236_3798662_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	2.0e-48	99.0
WP_069356963.1\|3798658_3799009_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.0e-39	65.5
WP_085948186.1\|3800584_3801741_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_001369053.1\|3802341_3802539_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_001013320.1\|3802783_3803209_-	hypothetical protein	NA	NA	NA	NA
WP_000270999.1\|3803205_3803589_-	hypothetical protein	NA	NA	NA	NA
WP_000221524.1\|3803756_3804326_-	inovirus Gp2 family protein	NA	NA	NA	NA
WP_000236756.1\|3804525_3804720_+	hypothetical protein	NA	NA	NA	NA
WP_001342960.1\|3805868_3806075_+	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_000782722.1\|3806163_3806772_+	hypothetical protein	NA	NA	NA	NA
WP_069357468.1\|3809230_3810103_+	hypothetical protein	NA	NA	NA	NA
WP_085947772.1\|3810661_3811874_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.3e-100	57.1
WP_085948186.1\|3811986_3813143_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000631719.1\|3815177_3815525_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	1.0e-42	72.0
WP_001341423.1\|3815521_3816196_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	30.8
WP_001218841.1\|3817186_3818452_-\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	2.7e-77	38.3
3818656:3818672	attR	NA	NA	NA	NA

DBSCAN-SWA_12

4081494 : 4088604

Escherichia_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001279007.1\|4081494_4082133_-	aldolase	A0A077SK32	Escherichia_phage	4.1e-82	74.5
WP_000590409.1\|4082129_4083392_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	4.4e-136	61.7
WP_069357503.1\|4083388_4084267_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	5.2e-112	73.8
WP_024226287.1\|4084462_4085230_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.5e-70	56.7
WP_001141339.1\|4085280_4085937_-	protein-serine/threonine phosphatase	K7P7V3	Enterobacteria_phage	5.6e-50	45.3
WP_001272924.1\|4086042_4088604_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6

DBSCAN-SWA_13

4456933 : 4561231

115

Enterobacteria_phage(62.16%)

tail,portal,tRNA,plate,head,capsid,transposase,integrase,terminase,holin

attL 4538950:4539009|attR 4561236:4562501

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_097310774.1\|4456933_4457629_-	LexA family transcriptional regulator	A0A0N7BTS4	Escherichia_phage	8.3e-129	96.1
WP_069357539.1\|4457704_4457911_+	helix-turn-helix transcriptional regulator	A0A0N7C2U7	Escherichia_phage	2.6e-22	94.3
WP_000229809.1\|4458138_4458345_+	hypothetical protein	G9L683	Escherichia_phage	1.1e-25	94.1
WP_000810176.1\|4458352_4458799_+	recombination protein NinB	A0A0N7C2V1	Escherichia_phage	3.4e-75	92.6
WP_000153270.1\|4458795_4459323_+	phage N-6-adenine-methyltransferase	K7PJZ4	Enterobacterial_phage	9.5e-101	100.0
WP_001254221.1\|4459319_4459502_+	NinE family protein	Q8H9Z6	Enterobacteria_phage	1.3e-28	98.3
WP_000612803.1\|4460005_4461778_-	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	0.0e+00	99.7
WP_001108084.1\|4462323_4462890_+	HNH endonuclease	A0A1U9AJK5	Stx1_converting_phage	6.6e-108	99.5
WP_069357540.1\|4462864_4463467_+	recombination protein NinG	A0A1U9AJF8	Stx1_converting_phage	3.5e-91	94.6
WP_001028854.1\|4463463_4464129_+	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001235461.1\|4464125_4464749_+	antitermination protein	K7PM87	Enterobacteria_phage	3.0e-114	100.0
WP_000783734.1\|4465289_4465613_+\|holin	phage holin, lambda family	G5DA93	Enterobacteria_phage	1.3e-52	100.0
WP_085948186.1\|4465963_4467119_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357542.1\|4467684_4468578_+	scaffolding protein	A0A088CPT0	Enterobacteria_phage	2.6e-127	97.6
WP_085948123.1\|4469040_4470209_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.7e-171	91.5
WP_069357543.1\|4471312_4471774_+\|head	head DNA stabilization protein	A5VW70	Enterobacteria_phage	3.5e-83	99.3
WP_069357544.1\|4471783_4473202_+	packaged DNA stabilization protein gp10	A0A088CQ70	Enterobacteria_phage	8.7e-274	99.2
WP_069357545.1\|4473201_4474050_+	hypothetical protein	Q716G6	Shigella_phage	3.8e-99	96.8
WP_069357546.1\|4474049_4474505_+	DUF2824 family protein	Q716G5	Shigella_phage	3.3e-86	98.0
WP_069357547.1\|4474507_4475197_+	DNA transfer protein	A0A2H4FUQ9	Salmonella_phage	2.3e-115	98.7
WP_069357548.1\|4475206_4476622_+	DNA transfer protein	I6RSG0	Salmonella_phage	2.4e-199	80.5
WP_069357549.1\|4476621_4478460_+	DNA transfer protein	A0A192Y934	Salmonella_phage	3.5e-251	75.7
WP_000890120.1\|4478479_4478809_-	hypothetical protein	NA	NA	NA	NA
WP_000821222.1\|4478927_4479347_+	hypothetical protein	B9UDL3	Salmonella_phage	1.5e-72	97.8
WP_000090241.1\|4479363_4479615_-	Arc family DNA-binding protein	B9UDL4	Salmonella_phage	1.3e-39	98.8
WP_000677939.1\|4479705_4479867_+	Arc family DNA-binding protein	A8CG91	Salmonella_phage	2.7e-22	98.1
WP_033546471.1\|4479935_4480814_+	antirepressor	I6R977	Salmonella_phage	1.5e-95	78.1
WP_094188220.1\|4480915_4482943_+	hypothetical protein	Q716G1	Shigella_phage	3.0e-78	58.4
WP_069357550.1\|4483035_4484193_-\|integrase	prophage integrase IntS	A5VW56	Enterobacteria_phage	6.9e-221	99.2
WP_000368131.1\|4484504_4485437_-	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
WP_000776768.1\|4485730_4486486_+	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_024226479.1\|4486667_4487726_-	hypothetical protein	NA	NA	NA	NA
WP_001296861.1\|4488091_4489432_-	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_001296869.1\|4489803_4490088_+	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_000531955.1\|4490268_4491579_+	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_000426156.1\|4491578_4493723_+	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_001195819.1\|4493925_4494411_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_024226478.1\|4495085_4495649_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_024231067.1\|4495730_4498373_+	fimbrial usher protein YfcU	NA	NA	NA	NA
WP_001281615.1\|4498392_4499145_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_000842082.1\|4499119_4499668_+	fimbrial protein	NA	NA	NA	NA
WP_000730291.1\|4500120_4500645_+	fimbrial protein	NA	NA	NA	NA
WP_001356216.1\|4500631_4501504_+	DUF2544 domain-containing protein	NA	NA	NA	NA
WP_000730806.1\|4501625_4502177_-	endonuclease SmrB	NA	NA	NA	NA
WP_069357551.1\|4502342_4503275_+	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_000918470.1\|4503309_4504395_+	chorismate synthase	A0A291AU41	Pandoravirus	9.1e-90	48.4
WP_069357552.1\|4504398_4505223_+	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_069357553.1\|4505222_4506032_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_069357554.1\|4506031_4506580_+	elongation factor P hydroxylase	NA	NA	NA	NA
WP_000559764.1\|4506613_4506892_+	YfcL family protein	NA	NA	NA	NA
WP_000683799.1\|4507012_4509019_-\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_000817183.1\|4509177_4510398_+	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_069357555.1\|4510681_4511503_+	arabinose transporter	NA	NA	NA	NA
WP_000615813.1\|4511499_4512495_-	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_000215750.1\|4512724_4513516_-	site-specific DNA-methyltransferase	Q775B4	Bordetella_phage	8.7e-66	52.6
WP_032144146.1\|4513460_4513658_-	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_032140709.1\|4513907_4514048_-	Hok/Gef family protein	S5M7Q0	Escherichia_phage	3.8e-09	65.2
WP_085948186.1\|4514210_4515367_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000290462.1\|4515892_4516405_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	1.5e-90	97.1
WP_069357556.1\|4516460_4516835_+\|tail	phage tail protein	A0A0A7NPZ0	Enterobacteria_phage	2.6e-36	72.4
WP_000333503.1\|4516843_4516999_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	9.7e-22	96.1
WP_069357557.1\|4516985_4519793_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	98.2
WP_000979957.1\|4519805_4520294_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	3.0e-85	99.4
WP_000954205.1\|4520450_4521023_+	serine acetyltransferase	NA	NA	NA	NA
WP_069357558.1\|4521066_4521645_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	3.5e-96	89.0
WP_077775673.1\|4521644_4522499_-\|tail	tail fiber protein	K7PHC9	Enterobacteria_phage	9.8e-39	89.8
WP_000071720.1\|4523784_4524315_-\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	1.1e-93	99.4
WP_001111960.1\|4524307_4525204_-\|plate	baseplate J/gp47 family protein	A0A0A7NPY5	Enterobacteria_phage	6.0e-156	98.3
WP_001067552.1\|4525207_4525537_-	GPW/gp25 family protein	A0A0A7NQ90	Enterobacteria_phage	1.1e-54	99.1
WP_077886894.1\|4525554_4526121_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	8.6e-100	97.9
WP_000356339.1\|4526132_4526768_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	1.1e-114	100.0
WP_000920594.1\|4526760_4527228_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	2.6e-86	100.0
WP_077886868.1\|4527214_4527772_-	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	2.2e-63	94.1
WP_000072327.1\|4527768_4528161_-	M15 family metallopeptidase	A0A0A7NQ86	Enterobacteria_phage	5.8e-71	100.0
WP_000104350.1\|4528157_4528481_-\|holin	phage holin family protein	A0A0A7NRY9	Enterobacteria_phage	1.6e-50	99.1
WP_032197599.1\|4528483_4528684_-\|tail	tail protein X	A0A0A7NV57	Enterobacteria_phage	5.1e-31	97.0
WP_069357560.1\|4528683_4529178_-\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	3.5e-89	98.2
WP_069357561.1\|4529279_4530080_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	5.1e-130	91.4
WP_069357562.1\|4530125_4531178_-\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	4.0e-191	95.7
WP_001262673.1\|4531200_4532037_-\|capsid	GPO family capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	2.7e-150	100.0
WP_000613781.1\|4532191_4533943_+	helix-turn-helix domain-containing protein	A0A0A7NV54	Enterobacteria_phage	0.0e+00	97.9
WP_000087814.1\|4533942_4534989_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	2.2e-202	99.7
WP_069357563.1\|4535003_4535528_-	hypothetical protein	NA	NA	NA	NA
WP_001519213.1\|4536087_4536495_-	hypothetical protein	A0A0A7NRY2	Enterobacteria_phage	3.4e-21	90.0
WP_001163782.1\|4536491_4536824_-	carboxylate--amine ligase	A0A0A7NV51	Enterobacteria_phage	5.5e-54	96.4
WP_069357564.1\|4536887_4537199_-	plasmid partitioning/stability family protein	A0A0A7NPT5	Enterobacteria_phage	9.4e-48	95.1
WP_069357565.1\|4537203_4538163_-	plasmid segregation protein ParM	A0A0A7NPX4	Enterobacteria_phage	3.8e-180	99.1
4538950:4539009	attL	NA	NA	NA	NA
WP_085948186.1\|4539013_4540169_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_001471916.1\|4542335_4542701_-	hypothetical protein	A0A0A7NRY1	Enterobacteria_phage	1.9e-60	96.7
WP_077886869.1\|4542697_4543294_-	ash family protein	S5MQL6	Escherichia_phage	1.3e-08	44.6
WP_069357567.1\|4543325_4543625_-	hypothetical protein	A0A0A7NRX6	Enterobacteria_phage	1.1e-40	88.9
WP_000153707.1\|4543621_4543888_-	winged helix-turn-helix transcriptional regulator	A0A0A7NV47	Enterobacteria_phage	3.1e-31	77.3
WP_000985163.1\|4543884_4544088_-	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	1.9e-25	83.6
WP_029392824.1\|4544111_4544528_-	hypothetical protein	NA	NA	NA	NA
WP_000021655.1\|4544620_4544734_-	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	6.2e-10	100.0
WP_069357568.1\|4544730_4544973_-	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	5.2e-38	98.8
WP_000159462.1\|4544984_4545263_-	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	3.6e-35	81.5
WP_054192163.1\|4545273_4545624_-	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	5.2e-55	92.2
WP_000203260.1\|4545743_4545950_-	hypothetical protein	NA	NA	NA	NA
WP_000004248.1\|4545956_4546244_-	hypothetical protein	A0A0M4RCW1	Salmonella_phage	6.7e-24	53.7
WP_000581441.1\|4546359_4546680_+	helix-turn-helix transcriptional regulator	Q1JS29	Enterobacteria_phage	1.3e-12	45.0
WP_069357569.1\|4546776_4547781_+\|integrase	tyrosine-type recombinase/integrase	A0A0M4RTQ0	Salmonella_phage	2.2e-98	55.7
WP_024231164.1\|4547939_4549097_+	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	7.9e-23	29.1
WP_069357570.1\|4549162_4550176_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_024226472.1\|4550175_4550988_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_000364335.1\|4551070_4551730_+	DedA family protein	NA	NA	NA	NA
WP_000118404.1\|4551885_4552800_+	acetyl-CoA carboxylase, carboxyltransferase subunit beta	NA	NA	NA	NA
WP_024226471.1\|4552869_4554138_+	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000146992.1\|4554127_4554790_+	cell division protein DedD	NA	NA	NA	NA
WP_000262113.1\|4555048_4555537_+	colicin V production protein	NA	NA	NA	NA
WP_000334220.1\|4555573_4557091_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.9e-87	44.0
WP_000825704.1\|4557185_4557755_+	flavin prenyltransferase UbiX	NA	NA	NA	NA
WP_000422741.1\|4557971_4558397_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|4558393_4558744_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_085948186.1\|4560074_4561231_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
4561236:4562501	attR	NA	NA	NA	NA

DBSCAN-SWA_14

4828492 : 4837299

Enterobacteria_phage(44.44%)

terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069357603.1\|4828492_4829182_+	antitermination protein	I6PDF8	Cronobacter_phage	5.8e-58	47.6
WP_001302581.1\|4829366_4830110_+	hypothetical protein	NA	NA	NA	NA
WP_000499454.1\|4830195_4830354_+	DUF3927 family protein	NA	NA	NA	NA
WP_100224537.1\|4831346_4831577_-	hypothetical protein	NA	NA	NA	NA
WP_000992175.1\|4831735_4832269_+	lysozyme	B6DZ92	Enterobacteria_phage	6.2e-100	96.0
WP_001303555.1\|4832424_4832607_+	hypothetical protein	NA	NA	NA	NA
WP_001280929.1\|4832619_4832751_+	hypothetical protein	A0A0N7BYT9	Escherichia_phage	9.4e-10	88.4
WP_001208680.1\|4832978_4833164_+	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_001303878.1\|4833690_4834005_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001299328.1\|4834086_4834311_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	4.1e-21	92.7
WP_000235436.1\|4834705_4835215_+\|terminase	terminase small subunit	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_106898625.1\|4835471_4836041_+\|tail	phage tail fiber C-terminal domain-containing protein	B6DZB7	Enterobacteria_phage	1.7e-39	100.0
WP_001023460.1\|4836042_4836312_+\|tail	phage tail fiber C-terminal domain-containing protein	Q687E5	Enterobacteria_phage	7.1e-44	97.8
WP_000950982.1\|4836417_4837299_+	hypothetical protein	A5LH48	Enterobacteria_phage	3.9e-147	90.4

DBSCAN-SWA_15

4927091 : 5029337

Enterobacteria_phage(33.96%)

tail,tRNA,head,capsid,transposase,protease,integrase,terminase,lysis,holin

attL 4940617:4940676|attR 5008461:5009726

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087891248.1\|4927091_4928298_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	3.9e-97	62.2
WP_001128468.1\|4930714_4930879_+	hypothetical protein	NA	NA	NA	NA
WP_000973176.1\|4931343_4931889_+	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	NA	NA	NA	NA
WP_024226617.1\|4931885_4932629_+	adenosylcobinamide-GDP ribazoletransferase	NA	NA	NA	NA
WP_024226619.1\|4932640_4933720_+	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	NA	NA	NA	NA
WP_000986346.1\|4933781_4934717_+	L,D-transpeptidase	NA	NA	NA	NA
WP_001011483.1\|4935173_4936091_+	nitrogen assimilation transcriptional regulator NAC	NA	NA	NA	NA
WP_069357618.1\|4936192_4937143_+	HTH-type transcriptional regulator Cbl	NA	NA	NA	NA
WP_122985555.1\|4937260_4938904_+	toxic metabolite efflux MATE transporter YeeO	NA	NA	NA	NA
WP_000532912.1\|4939532_4940249_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
4940617:4940676	attL	NA	NA	NA	NA
WP_085948186.1\|4940681_4941837_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357619.1\|4941834_4943313_-	AMP nucleosidase	NA	NA	NA	NA
WP_000477884.1\|4945044_4946097_+	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_122367527.1\|4946358_4953435_-	inverse autotransporter adhesin YeeJ	NA	NA	NA	NA
WP_001515476.1\|4953924_4954722_-	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_024226620.1\|4954957_4955983_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.2e-102	58.2
WP_000096344.1\|4955982_4956186_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_069357621.1\|4957198_4957351_-	DUF1391 family protein	M4QQ57	Salicola_phage	1.1e-06	53.2
WP_001003379.1\|4957542_4957950_-	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	7.2e-24	45.4
WP_000476986.1\|4958027_4958255_+	transcriptional regulator	NA	NA	NA	NA
WP_069357622.1\|4958238_4958790_+	hypothetical protein	NA	NA	NA	NA
WP_000020543.1\|4958761_4959802_+	DNA-binding protein	A0A0U2RT81	Escherichia_phage	1.9e-89	86.7
WP_157909734.1\|4959713_4960256_+	replication protein	A0A0U2JGJ0	Escherichia_phage	4.4e-85	98.7
WP_001340033.1\|4960362_4960563_+	hypothetical protein	A0A0U2SAW4	Escherichia_phage	5.9e-11	93.9
WP_001227887.1\|4961006_4961849_+	hypothetical protein	NA	NA	NA	NA
WP_000827089.1\|4962887_4964261_+	ATP-binding protein	NA	NA	NA	NA
WP_001124204.1\|4964247_4964883_+	HNH endonuclease	NA	NA	NA	NA
WP_000887487.1\|4965139_4965352_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.1e-23	81.4
WP_032285709.1\|4965709_4967323_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.5e-181	63.4
WP_000624722.1\|4967353_4967704_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|4967700_4968126_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_069357623.1\|4968179_4970105_+\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	97.1
WP_001063106.1\|4970149_4970371_+	hypothetical protein	B6DZA0	Enterobacteria_phage	2.2e-35	98.6
WP_000125988.1\|4972897_4973224_+\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_069357624.1\|4973233_4973584_+\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.0e-58	99.1
WP_000573391.1\|4973580_4974027_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001275476.1\|4974435_4975152_+	immunoglobulin domain-containing protein	A0A0P0ZD29	Stx2-converting_phage	5.6e-128	98.7
WP_001030043.1\|4975157_4975532_+\|tail	phage tail assembly chaperone	A0A0P0ZE84	Stx2-converting_phage	1.7e-64	99.2
WP_122993730.1\|4975627_4975837_+	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	2.6e-30	92.8
WP_069357625.1\|4975887_4979130_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	95.4
WP_000807944.1\|4979122_4979464_+\|tail	phage tail protein	H6WZM2	Escherichia_phage	1.2e-61	98.2
WP_069357626.1\|4979463_4980162_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	3.2e-128	96.1
WP_069357142.1\|4980172_4980916_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	3.3e-147	97.6
WP_158707115.1\|4980861_4981494_+\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	1.2e-102	98.1
WP_000649829.1\|4981762_4982290_-	superoxide dismutase family protein	Q9MC02	Salmonella_phage	1.8e-59	60.5
WP_069357629.1\|4982423_4985900_+	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	96.8
WP_053888632.1\|4985966_4986566_+	Ail/Lom family outer membrane beta-barrel protein	B6ETG5	Enterobacteria_phage	1.7e-109	98.5
WP_069357630.1\|4986630_4987944_+\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	2.8e-77	98.9
WP_001023386.1\|4987945_4988215_+\|tail	phage tail fiber C-terminal domain-containing protein	A0A1I9LJT0	Stx_converting_phage	6.0e-43	95.5
WP_069357631.1\|4988327_4988903_+	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	4.1e-57	60.0
WP_001118087.1\|4989193_4989775_+	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	7.9e-48	54.3
WP_075209616.1\|4989842_4990478_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.6e-73	90.7
WP_001144080.1\|4991737_4992388_-	T3SS effector NleG family protein	B6DZZ5	Stx2-converting_phage	2.8e-25	37.2
WP_001132165.1\|4992570_4993161_+	bfpT-regulated chaperone	NA	NA	NA	NA
WP_000799399.1\|4993439_4994303_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000531601.1\|4994286_4995423_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	9.4e-29	39.8
WP_069357632.1\|4995672_4996899_+	peptidase T	NA	NA	NA	NA
WP_064226077.1\|4996947_4998069_-	[50S ribosomal protein L16]-arginine 3-hydroxylase	NA	NA	NA	NA
WP_000735412.1\|4998144_4999605_-	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_001265481.1\|4999604_5000276_-	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000423729.1\|5000444_5001815_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
WP_001297479.1\|5001818_5002460_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_001297484.1\|5002495_5003602_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000476089.1\|5003655_5004117_-	phosphatase NudJ	NA	NA	NA	NA
WP_001248692.1\|5004126_5004780_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000444487.1\|5004951_5006202_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_077886876.1\|5006315_5007230_-\|integrase	tyrosine-type recombinase/integrase	Q77Z02	Phage_21	3.3e-173	99.0
WP_085948186.1\|5007298_5008455_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_000088653.1\|5008714_5008951_-	excisionase	NA	NA	NA	NA
WP_000488406.1\|5009090_5009330_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	3.9e-38	94.9
WP_000763364.1\|5009377_5009596_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	1.8e-34	95.8
WP_000188880.1\|5009694_5009910_-	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	2.9e-32	98.6
5008461:5009726	attR	NA	NA	NA	NA
WP_000544528.1\|5010827_5011133_+\|holin	phage holin family protein	A0A286N2Q5	Klebsiella_phage	7.0e-40	87.6
WP_001180491.1\|5011119_5011596_+	glycoside hydrolase family protein	K7PKV2	Enterobacteria_phage	1.0e-85	96.8
WP_012738274.1\|5011812_5011995_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	1.7e-17	100.0
WP_000738495.1\|5012085_5012379_-	serum resistance lipoprotein Bor	K7PL54	Enterobacteria_phage	1.5e-47	99.0
WP_000079504.1\|5012681_5013092_-	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	2.7e-71	98.5
WP_069357633.1\|5013377_5013584_+	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	2.2e-29	98.5
WP_001300120.1\|5013748_5013943_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	1.5e-27	98.4
WP_000453622.1\|5014331_5014877_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	3.1e-94	98.3
WP_047651814.1\|5014851_5016777_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.8
WP_000198149.1\|5016773_5016980_+	gpW family protein	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_069357634.1\|5019015_5022087_+\|tail	prophage tail fiber N-terminal domain-containing protein	U5N099	Enterobacteria_phage	1.9e-68	82.1
WP_000885594.1\|5022086_5022668_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.3e-103	95.3
WP_069357635.1\|5022787_5023678_-	manganese catalase family protein	NA	NA	NA	NA
WP_001079482.1\|5023696_5024203_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001166090.1\|5024239_5024740_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000134810.1\|5024818_5025001_-	general stress protein	NA	NA	NA	NA
WP_000239870.1\|5025498_5026167_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_024226582.1\|5026712_5028197_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_032205137.1\|5028383_5029337_-\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA

DBSCAN-SWA_16

5131191 : 5166687

Escherichia_phage(46.43%)

portal,tail,transposase,holin,terminase,integrase

attL 5126223:5126237|attR 5173110:5173124

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5126223:5126237	attL	NA	NA	NA	NA
WP_077886897.1\|5131191_5131674_-\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	7.0e-42	52.3
WP_085948186.1\|5131654_5132811_-\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_069357646.1\|5133097_5134138_+	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_157832601.1\|5134049_5134592_+	replication protein	A0A0U2JGJ0	Escherichia_phage	1.5e-85	98.7
WP_001449026.1\|5135254_5136013_+	AcfC family adhesin Paa	NA	NA	NA	NA
WP_000961821.1\|5136291_5136504_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.3e-16	72.9
WP_069357647.1\|5136777_5137038_+	hypothetical protein	NA	NA	NA	NA
WP_071961523.1\|5137104_5137383_+	hypothetical protein	A0A077KB22	Edwardsiella_phage	1.4e-05	37.1
WP_069357649.1\|5137384_5138440_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.2e-89	48.4
WP_000140002.1\|5138440_5138806_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	67.5
WP_069357650.1\|5138802_5139492_+	antiterminator	I6PDF8	Cronobacter_phage	2.8e-60	51.5
WP_069357651.1\|5141011_5142862_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.1
WP_024164617.1\|5143300_5143516_+\|holin	class II holin family protein	A0A0P0ZC45	Stx2-converting_phage	7.7e-33	98.6
WP_001135302.1\|5143515_5144013_+	lysozyme RrrD	A0A1B5FP97	Escherichia_phage	1.4e-90	97.6
WP_001208681.1\|5144229_5144415_+	membrane protein	A0A1U9AJA4	Stx1_converting_phage	2.9e-20	78.7
WP_001303878.1\|5144941_5145256_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_000074669.1\|5145337_5145562_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	2.7e-20	92.5
WP_001377217.1\|5145603_5146134_+	HNH endonuclease	H6WZK7	Escherichia_phage	1.2e-90	93.2
WP_069357653.1\|5146249_5146813_+\|terminase	terminase small subunit	B6DZ97	Enterobacteria_phage	4.7e-82	93.0
WP_085948186.1\|5147434_5148590_+\|transposase	IS3-like element IS600 family transposase	NA	NA	NA	NA
WP_185768400.1\|5148673_5149729_+\|terminase	terminase large subunit	H6WZK9	Escherichia_phage	1.0e-199	97.2
WP_054192414.1\|5151773_5151995_+	hypothetical protein	H6WZL1	Escherichia_phage	1.1e-31	90.4
WP_054446607.1\|5151940_5153305_+\|portal	phage portal protein	B6DZX6	Stx2-converting_phage	8.1e-253	96.5
WP_158707113.1\|5153301_5156538_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	78.9
WP_069357654.1\|5156530_5156872_+\|tail	phage tail protein	H6WZM2	Escherichia_phage	9.6e-62	98.2
WP_069357655.1\|5156871_5157570_+\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	6.4e-129	96.1
WP_071961524.1\|5157580_5158381_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	5.1e-146	97.2
WP_069357656.1\|5161118_5161388_+\|tail	phage tail fiber C-terminal domain-containing protein	Q6H9S8	Enterobacteria_phage	3.5e-43	95.5
WP_069357657.1\|5161607_5162150_+	hypothetical protein	Q9LA55	Enterobacteria_phage	1.4e-51	68.6
WP_106409363.1\|5162094_5162289_+\|tail	phage tail fiber C-terminal domain-containing protein	A0A2R2Z347	Escherichia_phage	1.1e-09	87.2
WP_001025663.1\|5162631_5163954_-	type III secretion system effector NleA	H6WZN2	Escherichia_phage	2.1e-221	83.9
WP_106409364.1\|5165546_5165669_+\|tail	phage tail fiber C-terminal domain-containing protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
WP_069357658.1\|5165775_5166687_+	type III secretion system effector kinase NleH1-2	A5LH48	Enterobacteria_phage	1.6e-132	81.5
5173110:5173124	attR	NA	NA	NA	NA

DBSCAN-SWA_17

5172406 : 5190303

Enterobacteria_phage(54.55%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_169301324.1\|5172406_5173057_+	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	8.6e-27	32.4
WP_000063650.1\|5173936_5175223_-	DUF3596 domain-containing protein	Q20GI2	Phage_258-320	6.9e-254	99.8
WP_001193437.1\|5175256_5175511_-	excisionase family protein	Q859D3	Escherichia_coli_phage	3.0e-44	100.0
WP_001484100.1\|5175702_5176074_-	DUF5406 family protein	Q8W655	Enterobacteria_phage	2.3e-61	95.1
WP_000720006.1\|5176114_5176942_-	hypothetical protein	Q8W654	Enterobacteria_phage	1.2e-129	97.5
WP_001365075.1\|5177311_5177884_-	hypothetical protein	Q8W653	Enterobacteria_phage	5.5e-78	71.3
WP_000553977.1\|5177889_5178072_-	hypothetical protein	Q8W652	Enterobacteria_phage	2.9e-09	52.7
WP_000147364.1\|5178270_5178471_-	hypothetical protein	NA	NA	NA	NA
WP_000387836.1\|5178467_5179169_-	helix-turn-helix domain-containing protein	A0A1B5FPB8	Escherichia_phage	1.5e-37	59.7
WP_000789654.1\|5179317_5180007_-	LexA family transcriptional regulator	A0A1B5FPF4	Escherichia_phage	3.0e-115	88.2
WP_000944728.1\|5180163_5180397_+	helix-turn-helix domain-containing protein	A0A1B5FPK9	Escherichia_phage	1.2e-28	77.0
WP_001090254.1\|5180478_5181186_+	Rha family transcriptional regulator	Q8W645	Enterobacteria_phage	1.6e-114	90.2
WP_000587259.1\|5181294_5181957_+	ash family protein	Q8W643	Enterobacteria_phage	3.7e-110	92.5
WP_000621233.1\|5181953_5182187_+	hypothetical protein	A0A1C9II64	Salmonella_phage	1.6e-12	47.2
WP_001247844.1\|5182173_5183082_+	hypothetical protein	Q8W642	Enterobacteria_phage	2.4e-59	94.0
WP_069357085.1\|5183092_5183971_+	ATP-binding protein	Q8W641	Enterobacteria_phage	6.0e-140	95.6
WP_000203852.1\|5183967_5185368_+	replicative DNA helicase	Q8W640	Enterobacteria_phage	1.7e-245	92.4
WP_001065352.1\|5185364_5185622_+	hypothetical protein	Q8W639	Enterobacteria_phage	1.2e-21	71.1
WP_001202271.1\|5185673_5186663_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	8.9e-193	98.2
WP_001204809.1\|5186681_5187062_+	antitermination protein Q	S5M7R9	Escherichia_phage	1.4e-66	99.2
WP_000917741.1\|5187277_5187475_+	hypothetical protein	A0A0P0ZDH6	Stx2-converting_phage	8.0e-29	100.0
WP_000483505.1\|5187626_5188685_+	site-specific DNA-methyltransferase	A0A0N7KZF8	Stx2-converting_phage	2.9e-205	98.0
WP_000738072.1\|5190033_5190303_+	Shiga toxin Stx2a subunit B	Q6DWN4	Enterobacteria_phage	1.2e-43	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP012493

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30126 : 37603

Escherichia_phage(33.33%)

integrase

attL 22399:22412|attR 36149:36162

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
22399:22412	attL	NA	NA	NA	NA
WP_074384196.1\|30126_30621_+\|integrase	tyrosine-type recombinase/integrase	I3WFA4	Macacine_betaherpesvirus	5.3e-53	95.5
WP_021499534.1\|30758_31034_-	hypothetical protein	NA	NA	NA	NA
WP_069356972.1\|31027_31672_-	AAA family ATPase	A0A222YXS3	Escherichia_phage	8.8e-40	43.5
WP_001103690.1\|31900_32872_+	hypothetical protein	A0A222YXF2	Escherichia_phage	7.4e-67	42.9
WP_000340832.1\|32876_33269_+	plasmid partitioning/stability family protein	NA	NA	NA	NA
WP_069356973.1\|33273_34533_-	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	4.7e-138	59.0
WP_000618110.1\|34965_35214_-	DinI-like family protein	Q2A098	Sodalis_phage	1.9e-14	48.0
WP_021499538.1\|35632_36535_+	DUF1281 domain-containing protein	NA	NA	NA	NA
36149:36162	attR	NA	NA	NA	NA
WP_001732000.1\|36531_36843_+	hypothetical protein	NA	NA	NA	NA
WP_069356974.1\|36919_37603_+	DNA methylase	A0A2I7RE86	Vibrio_phage	3.9e-30	36.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP012492

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

25053 : 34554

Enterobacteria_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024257415.1\|25053_26259_+	AAA family ATPase	Q1MVJ3	Enterobacteria_phage	4.3e-205	89.0
WP_001233382.1\|26255_27227_+	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	3.4e-112	67.9
WP_000080195.1\|28502_30116_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_069356963.1\|30146_30497_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.0e-39	65.5
WP_000422686.1\|30493_30919_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	2.0e-48	99.0
WP_001297096.1\|31477_32257_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_069356965.1\|32256_33237_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	2.1e-186	94.7
WP_085948186.1\|33398_34554_+\|transposase	IS3-like element IS600 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012491

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP014583

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP012493

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP012492

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection