CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP015835	Escherichia coli strain MS6198 plasmid pMS6198A, complete sequence	0 crisprs	DEDDh	0	0	0
NZ_CP015834	Escherichia coli strain MS6198 chromosome, complete genome	5 crisprs	DinG,cas3,DEDDh,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,RT,WYL,PD-DExK	2	32	12
NZ_CP015836	Escherichia coli strain MS6198 plasmid pMS6198B, complete sequence	0 crisprs	csa3	0	0	1
NZ_CP015838	Escherichia coli strain MS6198 plasmid pMS6198D, complete sequence	0 crisprs	RT	0	0	0
NZ_CP015837	Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence	0 crisprs	cas14j	0	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

107 : 97452

107

Escherichia_phage(64.36%)

transposase,holin,tail,terminase,head,portal,integrase

attL 26450:26466|attR 75926:75942

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000047923.1\|107_1541_-	bleomycin hydrolase	A0A1B0VAD6	Salmonella_phage	3.7e-272	100.0
WP_000002800.1\|1537_1894_-	hypothetical protein	Q71TP1	Escherichia_phage	1.0e-61	100.0
WP_033560574.1\|1893_5619_-	transglycosylase SLT domain-containing protein	A0A1B0VDM8	Salmonella_phage	0.0e+00	85.8
WP_000926342.1\|5700_6582_-	hypothetical protein	Q71TC9	Escherichia_phage	2.7e-172	98.6
WP_000523980.1\|6596_7208_-	hypothetical protein	Q71TN8	Escherichia_phage	2.9e-109	99.5
WP_023153778.1\|7218_7785_-	hypothetical protein	Q1MVL0	Enterobacteria_phage	1.1e-99	99.5
WP_032192786.1\|8015_8909_+	DUF4760 domain-containing protein	A0A1B5FPC5	Escherichia_phage	3.4e-26	30.3
WP_001057312.1\|8960_9437_-	hypothetical protein	NA	NA	NA	NA
WP_000093548.1\|9459_9810_-	hypothetical protein	NA	NA	NA	NA
WP_001396852.1\|10168_10288_+	ash family protein	NA	NA	NA	NA
WP_071550046.1\|10306_10528_+	host cell division inhibitor Icd-like protein	Q38557	Escherichia_phage	9.3e-26	80.3
WP_033560573.1\|10524_11616_+	phage antirepressor KilAC domain-containing protein	A0A077SLR9	Escherichia_phage	7.1e-159	79.8
WP_001187875.1\|11780_12581_+	phage antirepressor KilAC domain-containing protein	Q1MVK4	Enterobacteria_phage	1.9e-148	100.0
WP_062914760.1\|12610_13456_+	hypothetical protein	Q1MVK3	Enterobacteria_phage	1.8e-149	97.5
WP_052761440.1\|13720_14776_+	ParA family protein	H2BD62	Pseudomonas_phage	9.0e-143	70.8
WP_001561122.1\|14845_15133_-	DUF3892 domain-containing protein	NA	NA	NA	NA
WP_061327236.1\|15421_16018_-	hypothetical protein	A0A1B0VBK8	Salmonella_phage	6.3e-109	99.5
WP_001615627.1\|16189_16699_-	hypothetical protein	A0A077SK14	Escherichia_phage	1.7e-91	100.0
WP_000035302.1\|16710_17292_-	hypothetical protein	A0A077SL48	Escherichia_phage	4.5e-104	100.0
WP_000041756.1\|17327_18143_-	hypothetical protein	A0A1B0V835	Salmonella_phage	1.2e-113	99.6
WP_000085137.1\|18152_19742_-	hypothetical protein	Q71TB2	Escherichia_phage	2.9e-302	98.9
WP_069383073.1\|19802_21509_-	hypothetical protein	Q1MVJ5	Enterobacteria_phage	1.8e-310	94.2
WP_000038866.1\|21734_22736_-	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	1.7e-178	100.0
WP_001285362.1\|22752_23949_-	AAA family ATPase	A0A077SL49	Escherichia_phage	1.6e-225	100.0
WP_032247076.1\|24117_24927_-	GIY-YIG nuclease family protein	A0A077SK46	Escherichia_phage	3.2e-156	98.1
WP_001113742.1\|25219_26104_-	RepB family plasmid replication initiator protein	A0A077SLP3	Escherichia_phage	2.1e-161	100.0
WP_029401364.1\|26439_26832_-	hypothetical protein	Q1MVJ1	Enterobacteria_phage	2.0e-71	98.5
26450:26466	attL	NA	NA	NA	NA
WP_032333495.1\|27009_27432_-	hypothetical protein	Q71TL5	Escherichia_phage	1.2e-58	90.7
WP_069383074.1\|27471_28260_-	hypothetical protein	A0A077SK48	Escherichia_phage	3.0e-114	95.0
WP_001177862.1\|28721_29006_+	hypothetical protein	Q71TA2	Escherichia_phage	2.5e-47	97.9
WP_000472529.1\|28998_29904_+	recombination-associated protein RdgC	A0A077SK17	Escherichia_phage	1.6e-159	99.7
WP_000660970.1\|29900_31919_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	Q1MVI4	Enterobacteria_phage	0.0e+00	96.6
WP_000751808.1\|33893_34721_+	hypothetical protein	A0A077SLJ6	Escherichia_phage	1.6e-131	100.0
WP_001276602.1\|35110_36475_+	replicative DNA helicase	O80281	Escherichia_phage	3.6e-253	99.6
WP_001569381.1\|36474_36777_+	hypothetical protein	NA	NA	NA	NA
WP_069383075.1\|36773_37748_+	hypothetical protein	Q71TK3	Escherichia_phage	4.2e-187	98.8
WP_000535205.1\|37794_38427_-	hypothetical protein	A0A1B0V872	Salmonella_phage	6.9e-90	100.0
WP_000212027.1\|38419_39436_-	hypothetical protein	A0A077SLQ1	Escherichia_phage	6.6e-191	99.1
WP_015974270.1\|39437_40223_-	hypothetical protein	Q71T90	Escherichia_phage	9.4e-145	100.0
WP_000896796.1\|40209_40938_-	hypothetical protein	A0A077SK19	Escherichia_phage	2.7e-138	99.6
WP_001141908.1\|40941_42159_-	hypothetical protein	A0A077SL53	Escherichia_phage	1.1e-224	100.0
WP_000235786.1\|42168_42546_-	hypothetical protein	Q38620	Escherichia_phage	2.2e-67	100.0
WP_000840931.1\|42692_42938_+	hypothetical protein	Q71T86	Escherichia_phage	5.7e-40	100.0
WP_069383076.1\|42940_43519_+	VRR-NUC domain-containing protein	Q71T85	Escherichia_phage	3.4e-99	92.2
WP_000096174.1\|43585_43741_+	hypothetical protein	Q71TJ4	Escherichia_phage	7.0e-20	100.0
WP_000484110.1\|44242_44869_+	norphogenetic protein	Q71T82	Escherichia_phage	6.1e-123	100.0
WP_023352819.1\|44865_45543_+	metallophosphoesterase	Q71TJ1	Escherichia_phage	1.1e-133	99.6
WP_000684845.1\|45539_46241_+	hypothetical protein	Q1MVG6	Enterobacteria_phage	4.2e-144	100.0
WP_000107689.1\|46542_47805_+	hypothetical protein	A0A1B0V7L1	Salmonella_phage	5.4e-235	100.0
WP_069383077.1\|47877_48384_+	3'-phosphatase	A0A1B0VAK0	Salmonella_phage	1.2e-92	98.8
WP_000675639.1\|48578_49307_+	hypothetical protein	Q71T76	Escherichia_phage	4.9e-140	99.1
WP_072650063.1\|49310_50189_+	phosphoadenosine phosphosulfate reductase family protein	A0A2R2Z314	Escherichia_phage	1.3e-171	95.5
WP_000158002.1\|50185_50389_+	hypothetical protein	A0A2R2Z313	Escherichia_phage	1.5e-30	94.0
WP_023352820.1\|50381_50621_+	hypothetical protein	S5MQM0	Escherichia_phage	1.3e-36	97.5
WP_063816970.1\|50617_51265_+	ead/Ea22-like family protein	K7P881	Enterobacteria_phage	1.7e-54	60.2
WP_000797276.1\|51437_51626_+	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	5.3e-30	96.8
WP_000951710.1\|51627_51837_+	hypothetical protein	A0A0F6TJE4	Escherichia_coli_O157_typing_phage	8.8e-34	94.2
WP_068880404.1\|51833_53111_+	DUF551 domain-containing protein	Q1MVF7	Enterobacteria_phage	4.1e-81	59.1
WP_000516537.1\|53193_53427_+	hypothetical protein	A0A1B0V7L5	Salmonella_phage	1.6e-36	97.4
WP_000269004.1\|53605_53899_+	hypothetical protein	A0A077SK23	Escherichia_phage	3.1e-45	92.8
WP_068880407.1\|53905_54280_+	hypothetical protein	A0A1B0VBU7	Salmonella_phage	5.4e-66	96.0
WP_000057451.1\|54261_54912_+	hypothetical protein	A0A077SK55	Escherichia_phage	4.9e-99	96.7
WP_001142394.1\|54895_55180_+	hypothetical protein	A0A222YXZ5	Escherichia_phage	2.4e-05	100.0
WP_001344848.1\|55164_55374_-	hypothetical protein	A0A222YY00	Escherichia_phage	1.1e-31	98.6
WP_001283837.1\|55547_55799_+	DNA polymerase III subunit theta	A0A077SLL5	Escherichia_phage	1.4e-38	100.0
WP_000506726.1\|55922_56312_+	DNA repair protein	Q1MVE7	Enterobacteria_phage	1.4e-69	99.2
WP_001190712.1\|56384_56606_+	type II toxin-antitoxin system Phd/YefM family antitoxin	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
WP_001216047.1\|56605_56986_+	type II toxin-antitoxin system death-on-curing family toxin	Q71T66	Escherichia_phage	2.5e-63	99.2
WP_000113019.1\|56990_57170_+	hypothetical protein	Q71TH5	Escherichia_phage	2.7e-23	98.3
WP_000644102.1\|57197_58241_+	DUF968 domain-containing protein	A0A1B0VBU2	Salmonella_phage	3.0e-207	99.4
WP_001312282.1\|58329_58782_+	late promoter-activating protein (Gp10)	Q71T63	Escherichia_phage	6.7e-79	99.3
WP_032335092.1\|58868_60062_+	hypothetical protein	Q5QBP3	Enterobacteria_phage	7.4e-202	96.7
WP_000124150.1\|60061_61546_+\|terminase	terminase	Q71T61	Escherichia_phage	1.5e-292	100.0
WP_000611656.1\|61570_62422_-	hypothetical protein	A0A077SLM8	Escherichia_phage	6.1e-158	99.6
WP_000874154.1\|62532_62742_-	hypothetical protein	Q5XLQ8	Enterobacteria_phage	4.8e-32	100.0
WP_000542332.1\|63346_63568_+	hypothetical protein	A0A077SLI9	Escherichia_phage	3.4e-36	100.0
WP_000067530.1\|63575_64607_+\|integrase	tyrosine-type recombinase/integrase	Q71TG5	Escherichia_phage	9.9e-195	100.0
WP_001224236.1\|64657_64969_+	hypothetical protein	A0A077SK03	Escherichia_phage	2.3e-46	99.0
WP_000848375.1\|65215_65776_+	Ref family protein	A0A077SL37	Escherichia_phage	5.0e-100	100.0
WP_071961621.1\|65965_66607_+	maturation control protein	A0A077SK30	Escherichia_phage	5.3e-114	98.6
WP_023156640.1\|66663_67971_+	SIR2 family protein	NA	NA	NA	NA
WP_000747846.1\|68017_68266_-	hypothetical protein	Q71TG0	Escherichia_phage	1.8e-41	100.0
WP_000224043.1\|68262_68703_-	hypothetical protein	A0A077SLF0	Escherichia_phage	1.7e-79	100.0
WP_069383079.1\|68736_75504_-	N-6 DNA methylase	Q1MVN7	Enterobacteria_phage	0.0e+00	98.8
WP_069383080.1\|75579_77301_+\|portal	phage portal protein	A0A077SL38	Escherichia_phage	0.0e+00	99.5
75926:75942	attR	NA	NA	NA	NA
WP_001312284.1\|77333_78464_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q9G0F2	Phage_Gifsy-1	9.2e-186	84.5
WP_000132937.1\|78576_79596_+\|head	head processing protein	Q71TR6	Escherichia_phage	4.4e-179	96.8
WP_024187336.1\|79640_79889_-	hypothetical protein	Q71TF4	Escherichia_phage	1.0e-36	100.0
WP_001345478.1\|79881_80439_-	lysozyme	Q71TF3	Escherichia_phage	4.2e-107	100.0
WP_000068865.1\|80608_81097_+	single-stranded DNA-binding protein	A0A1B0VAF5	Salmonella_phage	5.0e-88	100.0
WP_001376650.1\|81294_81972_+	DUF2829 domain-containing protein	A0A1B0VBT1	Salmonella_phage	1.2e-127	99.6
WP_024946700.1\|81978_82761_+	hypothetical protein	A0A1B0VDP8	Salmonella_phage	7.1e-145	99.6
WP_001165936.1\|82790_83099_-	hypothetical protein	O21974	Escherichia_phage	5.4e-48	97.1
WP_033559806.1\|83088_86076_-	hypothetical protein	A0A1B0VFX4	Salmonella_phage	0.0e+00	99.6
WP_000175491.1\|86088_86454_-	hypothetical protein	A0A1B0V846	Salmonella_phage	9.3e-47	98.3
WP_032333432.1\|86450_88370_-	phage protein DarA	A0A1B0V7H1	Salmonella_phage	0.0e+00	98.6
WP_032333430.1\|88371_88974_-	hypothetical protein	Q1MVM6	Enterobacteria_phage	1.2e-99	99.5
WP_000580776.1\|88960_89404_-	hypothetical protein	A0A077SK09	Escherichia_phage	1.3e-82	100.0
WP_000887652.1\|89400_89730_-\|holin	holin	Q37876	Escherichia_phage	1.3e-52	100.0
WP_000145199.1\|89804_90068_-	hypothetical protein	Q71TD9	Escherichia_phage	1.1e-22	67.1
WP_001165547.1\|90503_91076_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	4.4e-83	85.0
WP_071961622.1\|91633_92131_+\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	1.9e-50	60.1
WP_023156927.1\|92141_92570_+\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	1.3e-39	54.9
WP_000503756.1\|92580_93078_+\|tail	tail fiber protein	K7P7Q7	Enterobacteria_phage	9.1e-45	59.1
WP_000367942.1\|93083_93695_-\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	3.6e-83	78.6
WP_071961623.1\|93694_94153_-\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	1.4e-44	57.4
WP_001286325.1\|97017_97452_-	hypothetical protein	A0A077SLL3	Escherichia_phage	7.4e-75	99.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP015834

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015834_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015834_1

1016071-1016218

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGTACAGGCAGCTTAGAAA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP015834_1

>merge|NZ_CP015834|1|1016071-1016218|CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAAGGAACAATCTTGCAAAGGCTGTGAAAGTTGGCGTTCACTGCCGTACAGGCAGCTTAGAAATTCACTGGTAACATACTCCACCCGCCCACCATGTTCACTGCCGTACAGGCAGATAAAATG

>NZ_CP015834|1|1|1016071-1016218|CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAA	GGAACAATCTTGCAAAGGCTGTGAAAGTTGGC
GTTCACTGCCGTACAGGCAGCTTAGAAA	TTCACTGGTAACATACTCCACCCGCCCACCAT
GTTCACTGCCGTACAGGCAGATAAAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015834.1\|WP_022645454.1\|1019574_1021341_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NZ_CP015834.1\|WP_022645447.1\|1006463_1006706_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015834.1\|WP_000934041.1\|1013579_1015856_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NZ_CP015834.1\|WP_000770177.1\|1007140_1007440_+\|DUF4222-domain-containing-protein	unknown	unknown	gnl\|CDD\|372855
NZ_CP015834.1\|WP_022645455.1\|1023601_1027672_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NZ_CP015834.1\|WP_000228473.1\|1022972_1023467_+\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
NZ_CP015834.1\|WP_022645449.1\|1006901_1007135_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015834.1\|WP_001040187.1\|1016603_1016822_-\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NZ_CP015834.1\|WP_022645448.1\|1006678_1006900_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015834.1\|WP_000520781.1\|1013228_1013549_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP015834.1\|WP_022645452.1\|1012091_1012373_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015834.1\|WP_000537432.1\|1021463_1022429_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NZ_CP015834.1\|WP_022645451.1\|1009943_1011833_+\|Clp-protease-ClpP	unknown	unknown	gnl\|CDD\|132927
NZ_CP015834.1\|WP_022645450.1\|1007436_1008846_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|316042
NZ_CP015834.1\|WP_000067771.1\|1028452_1029796_+\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NZ_CP015834.1\|WP_001114742.1\|1009752_1009947_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015834.1\|WP_000886683.1\|1029886_1031179_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP015834.1\|WP_001295343.1\|1027830_1028442_+\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NZ_CP015834.1\|WP_022645453.1\|1017106_1017811_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP015834.1\|WP_001202192.1\|1017852_1019574_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865

Protein	Function_ID	Function_description	E-value
NZ_CP015834.1\|WP_022645454.1\|1019574_1021341_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP015834.1\|WP_000934041.1\|1013579_1015856_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NZ_CP015834.1\|WP_000770177.1\|1007140_1007440_+\|DUF4222-domain-containing-protein	gnl\|CDD\|372855	pfam13973, DUF4222, Domain of unknown function (DUF4222). This short protein is likely to be of phage origin. For example it is found in the Enterobacteria phage YYZ-2008. It is largely found in enteric bacteria. The molecular function of this protein is unknown.	2.39229e-22
NZ_CP015834.1\|WP_022645455.1\|1023601_1027672_+\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NZ_CP015834.1\|WP_000228473.1\|1022972_1023467_+\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
NZ_CP015834.1\|WP_001040187.1\|1016603_1016822_-\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NZ_CP015834.1\|WP_000520781.1\|1013228_1013549_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
NZ_CP015834.1\|WP_022645450.1\|1007436_1008846_+\|AAA-family-ATPase	gnl\|CDD\|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	1.63065e-39
NZ_CP015834.1\|WP_000537432.1\|1021463_1022429_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NZ_CP015834.1\|WP_022645451.1\|1009943_1011833_+\|Clp-protease-ClpP	gnl\|CDD\|132927	cd07016, S14_ClpP_1, Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease. Clp protease (caseinolytic protease; ClpP; Peptidase S14) is a highly conserved serine protease present throughout in bacteria and eukaryota, but seems to be absent in archaea, mollicutes and some fungi. This subfamily only contains bacterial sequences. Clp proteases are involved in a number of cellular processes such as degradation of misfolded proteins, regulation of short-lived proteins and housekeeping removal of dysfunctional proteins. They are also implicated in the control of cell growth, targeting DNA-binding protein from starved cells. ClpP has also been linked to the tight regulation of virulence genes in the pathogens Listeria monocytogenes and Salmonella typhimurium. This enzyme belong to the family of ATP-dependent proteases; the functional Clp protease is comprised of two components: a proteolytic component and one of several regulatory ATPase components, both of which are required for effective levels of protease activity in the presence of ATP, although the proteolytic subunit alone does possess some catalytic activity. Active site consists of the triad Ser, His and Asp; some members have lost all of these active site residues and are therefore inactive, while others may have one or two large insertions. ClpP seems to prefer hydrophobic or non-polar residues at P1 or P1' positions in its substrate. The protease exists as a tetradecamer made up of two heptameric rings stacked back-to-back such that the catalytic triad of each subunit is located at the interface between three monomers, thus making oligomerization essential for function.	9.50704e-72
NZ_CP015834.1\|WP_000886683.1\|1029886_1031179_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP015834.1\|WP_000067771.1\|1028452_1029796_+\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP015834.1\|WP_001295343.1\|1027830_1028442_+\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
NZ_CP015834.1\|WP_022645453.1\|1017106_1017811_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.78168e-138
NZ_CP015834.1\|WP_001202192.1\|1017852_1019574_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0

>NZ_CP015834.1|WP_000934041.1|1013579_1015856_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NZ_CP015834.1|WP_000520781.1|1013228_1013549_+|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NZ_CP015834.1|WP_022645452.1|1012091_1012373_+|hypothetical-protein
MTEAELLGLIRRAGGISQQTDEQATQPDSVTAENYARVVAEVMRRDGIQLNGVDMRNIRTRVLELLAYRRRVEMYREKEKITYHWKKPERLRR
>NZ_CP015834.1|WP_022645451.1|1009943_1011833_+|Clp-protease-ClpP
MKTWFSIKAMADVVHVRIYDEIGGYGVKASALTDEINACGNASEIHLRIHSPGGDIFEGLAIYNALKNHPAKKIVHIEGMAASMASFIAMCGDHIVMPENAMMMIHAPRGVTAGVSGDVRRFADLMDKLGDTMAETYAGRTGRSKQEITSMMEAETWMDGNECKANGFADEVIPAITAMARIESKRIGDFSNMPEKIKSMISQKTGSGEQERLNGIRELFGTFNGRYNDLAISCLADSECSVENARERLLLAMGKESTPTNKTTPANLYYAYTDNGNITGDAMRQGLNARLGHERAERGNPYAMMSLFDMAQASLTHRGISTGSYGTRSQIVNAAFTHSSSDFTDILAGGAEKSVLAGWEHSGETFRQWTKKGSLSNFREARRVGLNGFSTLNKVPEGAEYKYITTSDRGEPIALATYGNIFSITRQAIINDDLDQLSTVPMAMGRAASRTVGNLVNLVLTGNVKLSDGIALFDKKHSNLIEAGLTTPGLSAARHLMRTQKDKNGEVLNIAPKFLLVPAALEDRALQMINSTAPFGADKNSGIFNPYHKLLDIIVDPRLDDISEKQWYMLSAQGTDTIEVAYLDGNDEPYLEQQEGFIVDGVAWKVRIDAGVAALDYRGMVKSGGTDSL
>NZ_CP015834.1|WP_001114742.1|1009752_1009947_+|hypothetical-protein
MPENNTRKPDKSATVHIDAGTMEKIERYQQFIKDNHPGMPVPTKGQITRSAVEYWYRATLGAWL
>NZ_CP015834.1|WP_022645450.1|1007436_1008846_+|AAA-family-ATPase
MKLAPNVKRLPKDKYTDAIIFAGIDAHSFAEHYIIAQAKKAGDPVPPVYLGRYQLSELDNLQIVDDGRYRATVIRAGNIEEPQLLTIATKLAIAGVQEARLLSENFELLEEWSDQLPRLREAWERGESLVMKKIPQRKTTLPMSVGSTGYDTQLDYVVKGIIPASSLCSIYGASGSYKSFLAGSWACHVSTGRQWGGRRVAHGAVLYVVGEGGIGVPRRVKAWEVVHGEQVKNLYLVNRPIFPAAPLDIDEMVIAARQVERETGKPVRMIILDTLARCFGGNDENDSRDMGAFIRGCDELKRRTGATVLVVHHSGKDETKGARGSSAFRASLDAEYRIRREDAGSEALVISCTKMKDAEELKEAAYDLRVVELFTDADGELITSLVVVDKPRPPVELERIEEAGNKTENHTALWGCIRSRTQHGDKCTIPLLRDDMKKLGYDTKHLKRWLAKLEKDDVIYIDGDDVGPL
>NZ_CP015834.1|WP_000770177.1|1007140_1007440_+|DUF4222-domain-containing-protein
MKLKYSGLTASGNTHPKFTRGDIYRDQYGGTVMIKGVEERRVTYRREGYEYDCVMPVYQFRRDFSLVQTAPHNVPTSNARARANIQKLKTMINGFRSKK
>NZ_CP015834.1|WP_022645449.1|1006901_1007135_+|hypothetical-protein
MRDIYQETIDRAFSALAYAEGMYEILQMWLETFGDNECDVKKARIITSLITLLEPVINELQEIETLHDRYNEQHTGE
>NZ_CP015834.1|WP_022645448.1|1006678_1006900_+|hypothetical-protein
MRDDRFNSLKQEFSGVSDDASDALSAISELIRASFFLIGTKEYKSTGIDVLSIAADYADFVTEVILRKTTDGD
>NZ_CP015834.1|WP_022645447.1|1006463_1006706_+|hypothetical-protein
MHNKTTPDAAAAALTTLMHALIDIECTAELAQGEEQKDRTQFALECIRYTATRSLNDAKNILIADCENGGGLCVMIVLIP
>NZ_CP015834.1|WP_001040187.1|1016603_1016822_-|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NZ_CP015834.1|WP_022645453.1|1017106_1017811_-|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWCEDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNKFWVPRCLFSPQE
>NZ_CP015834.1|WP_001202192.1|1017852_1019574_-|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEATLRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NZ_CP015834.1|WP_022645454.1|1019574_1021341_-|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQTALDNAWVSEFLPLLPQGIDMPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVAGGPFATLLAHRQEEI
>NZ_CP015834.1|WP_000537432.1|1021463_1022429_-|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NZ_CP015834.1|WP_000228473.1|1022972_1023467_+|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NZ_CP015834.1|WP_022645455.1|1023601_1027672_+|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEEDESHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPTQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPVQQPYYAPAPEQSAQQPYYAPAPEQSVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSAGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFTLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPIAPQQQYQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NZ_CP015834.1|WP_001295343.1|1027830_1028442_+|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NZ_CP015834.1|WP_000067771.1|1028452_1029796_+|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTKDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NZ_CP015834.1|WP_000886683.1|1029886_1031179_+|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG

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Crispr_ID: NZ_CP015834_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015834_2

3073624-3074507

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACTC	PILER-CR

14 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP015834_2

>merge|NZ_CP015834|2|3073624-3074507|CRT,CRISPRCasFinder,PILER-CR
GCGAGTTCTACCGCAGGGGCGGGGAATTCTAAGTGATATCCATCATCGCATCCAGTGCGCCCGGTTTATCCCCGCTGGCGCGGGGAACTCGCCGGAAAATATTCATGATGGGGGTGGTTATGGCGGTTTATCCCCGCTGGCGCGGGGAACTCGGGGCCGCCGTGTTCACATTTGCCTAATTTCCCGGTTTATCCCCGCTGGCGCGGGGAACTCAACATGTCTTTCGTCAATTTTGGCGCTATAAACGGTTTATCCCCGCTGGCGCGGGGAACTCTATATAAACGAGGTGAATTTATGGAAACTGTACGGTTTATCCCCGCTGGCGCGGGGAACTCGTTAGTTTTCTGAAAAAATTGTTTTCTTACGCTGGTTTATCCCCGCTGGCGCGGGGAACTCAATATTGTCGTGGACAAATGCCGGTGTTATTGCGGTTTATCCCCGCTGGCGCGGGGAACTCTTCGAGACACTTCTCTGCAAAATTAATGAAATCGGTTTATCCCCGCTGGCGCGGGGAACTCCAGGTATCAAGAAATAATCGAAGCCTTCATGACGGTTTATCCCCGCTGGCGCGGGGAACTCAATTGATTGCTGGGTGATATTGGAAAATGTTGCGGTTTATCCCCGCTGGCGCGGGGAACTCTACCGTACAGACTGCCGGATATTATTTTTTTGCGGTTTATCCCCGCTGGCGCGGGGAACTCCGACGTTCGACGAAATGCGCGATGGCGGTCGGCGGTTTATCCCCGCTGGCGCGGGGAACTCTTCTGCGTCCCCGATGTCTGGCCCGACTGGTCCGGTTTATCCCCGCTGGCGCGGGGAACTCTATATGACCGGAACACTTCCGCCTGACGTTTGCGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP015834|2|1|3073624-3074507|CRT
GCGAGTTCTACCGCAGGGGCGGGGAATTC	TAAGTGATATCCATCATCGCATCCAGTGCGCC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCCGGAAAATATTCATGATGGGGGTGGTTATGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GGGGCCGCCGTGTTCACATTTGCCTAATTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AACATGTCTTTCGTCAATTTTGGCGCTATAAA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATAAACGAGGTGAATTTATGGAAACTGTA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GTTAGTTTTCTGAAAAAATTGTTTTCTTACGC
TGGTTTATCCCCGCTGGCGCGGGGAACTC	AATATTGTCGTGGACAAATGCCGGTGTTATTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCGAGACACTTCTCTGCAAAATTAATGAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CAGGTATCAAGAAATAATCGAAGCCTTCATGA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AATTGATTGCTGGGTGATATTGGAAAATGTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TACCGTACAGACTGCCGGATATTATTTTTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CGACGTTCGACGAAATGCGCGATGGCGGTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCTGCGTCCCCGATGTCTGGCCCGACTGGTC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATGACCGGAACACTTCCGCCTGACGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP015834|2|2|3073685-3074507|CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCCGGAAAATATTCATGATGGGGGTGGTTATGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GGGGCCGCCGTGTTCACATTTGCCTAATTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AACATGTCTTTCGTCAATTTTGGCGCTATAAA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATAAACGAGGTGAATTTATGGAAACTGTA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GTTAGTTTTCTGAAAAAATTGTTTTCTTACGC
TGGTTTATCCCCGCTGGCGCGGGGAACTC	AATATTGTCGTGGACAAATGCCGGTGTTATTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCGAGACACTTCTCTGCAAAATTAATGAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CAGGTATCAAGAAATAATCGAAGCCTTCATGA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AATTGATTGCTGGGTGATATTGGAAAATGTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TACCGTACAGACTGCCGGATATTATTTTTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CGACGTTCGACGAAATGCGCGATGGCGGTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCTGCGTCCCCGATGTCTGGCCCGACTGGTC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATGACCGGAACACTTCCGCCTGACGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP015834|2|1|3073747-3074507|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GGGGCCGCCGTGTTCACATTTGCCTAATTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AACATGTCTTTCGTCAATTTTGGCGCTATAAA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATAAACGAGGTGAATTTATGGAAACTGTA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GTTAGTTTTCTGAAAAAATTGTTTTCTTACGCT
GGTTTATCCCCGCTGGCGCGGGGAACTCA	ATATTGTCGTGGACAAATGCCGGTGTTATTGC
GGTTTATCCCCGCTGGCGCGGGGAACTCT	TCGAGACACTTCTCTGCAAAATTAATGAAATC
GGTTTATCCCCGCTGGCGCGGGGAACTCC	AGGTATCAAGAAATAATCGAAGCCTTCATGAC
GGTTTATCCCCGCTGGCGCGGGGAACTCA	ATTGATTGCTGGGTGATATTGGAAAATGTTGC
GGTTTATCCCCGCTGGCGCGGGGAACTCT	ACCGTACAGACTGCCGGATATTATTTTTTTGC
GGTTTATCCCCGCTGGCGCGGGGAACTCC	GACGTTCGACGAAATGCGCGATGGCGGTCGGC
GGTTTATCCCCGCTGGCGCGGGGAACTCT	TCTGCGTCCCCGATGTCTGGCCCGACTGGTCC
GGTTTATCCCCGCTGGCGCGGGGAACTCT	ATATGACCGGAACACTTCCGCCTGACGTTTGC
GGTTTATCCCCGCTGGCGCGGGGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015834.1\|WP_000372392.1\|3071405_3072314_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP015834.1\|WP_022646035.1\|3074898_3075816_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP015834.1\|WP_001290706.1\|3084429_3086142_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP015834.1\|WP_000281399.1\|3075831_3076431_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP015834.1\|WP_022646031.1\|3066239_3067289_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP015834.1\|WP_001246104.1\|3068998_3069322_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP015834.1\|WP_022646033.1\|3072565_3073603_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP015834.1\|WP_000752798.1\|3078198_3078681_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|187801
NZ_CP015834.1\|WP_000517476.1\|3068493_3068805_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP015834.1\|WP_022646039.1\|3080596_3083263_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP015834.1\|WP_022646038.1\|3078673_3080182_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|236613
NZ_CP015834.1\|WP_001295182.1\|3065497_3066259_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP015834.1\|WP_022646032.1\|3069976_3071404_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP015834.1\|WP_001219242.1\|3067285_3067765_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP015834.1\|WP_001173673.1\|3069371_3069977_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP015834.1\|WP_000246131.1\|3067764_3068475_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP015834.1\|WP_022646036.1\|3076417_3077092_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
NZ_CP015834.1\|WP_022646034.1\|3074612_3074897_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP015834.1\|WP_022646040.1\|3083621_3084356_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP015834.1\|WP_022646037.1\|3077094_3078186_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843

Protein	Function_ID	Function_description	E-value
NZ_CP015834.1\|WP_000372392.1\|3071405_3072314_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP015834.1\|WP_022646035.1\|3074898_3075816_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.75252e-159
NZ_CP015834.1\|WP_001290706.1\|3084429_3086142_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP015834.1\|WP_000281399.1\|3075831_3076431_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	4.3792e-101
NZ_CP015834.1\|WP_022646031.1\|3066239_3067289_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP015834.1\|WP_001246104.1\|3068998_3069322_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP015834.1\|WP_022646033.1\|3072565_3073603_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP015834.1\|WP_000752798.1\|3078198_3078681_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187801	cd09670, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.51297e-33
NZ_CP015834.1\|WP_000517476.1\|3068493_3068805_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP015834.1\|WP_022646039.1\|3080596_3083263_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	0
NZ_CP015834.1\|WP_022646038.1\|3078673_3080182_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|236613	PRK09693, PRK09693, Cascade antiviral complex protein; Validated.	0
NZ_CP015834.1\|WP_001295182.1\|3065497_3066259_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP015834.1\|WP_022646032.1\|3069976_3071404_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP015834.1\|WP_001219242.1\|3067285_3067765_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP015834.1\|WP_001173673.1\|3069371_3069977_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP015834.1\|WP_000246131.1\|3067764_3068475_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.32778e-121
NZ_CP015834.1\|WP_022646036.1\|3076417_3077092_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	8.37717e-102
NZ_CP015834.1\|WP_022646034.1\|3074612_3074897_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.20986e-62
NZ_CP015834.1\|WP_022646040.1\|3083621_3084356_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	2.62447e-137
NZ_CP015834.1\|WP_022646037.1\|3077094_3078186_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	7.42279e-152

>NZ_CP015834.1|WP_022646033.1|3072565_3073603_+|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSVEATNWNLGNKDGYQQRSKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIILPLVKKLAKAS
>NZ_CP015834.1|WP_000372392.1|3071405_3072314_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP015834.1|WP_022646032.1|3069976_3071404_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLILIDRLSNVTVGAGMVHEPVSQATAAPSQFSVFELELNALVRRHFPHWGARDLLGDK
>NZ_CP015834.1|WP_001173673.1|3069371_3069977_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP015834.1|WP_001246104.1|3068998_3069322_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP015834.1|WP_000517476.1|3068493_3068805_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP015834.1|WP_000246131.1|3067764_3068475_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKHVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP015834.1|WP_001219242.1|3067285_3067765_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP015834.1|WP_022646031.1|3066239_3067289_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHSREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELVELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP015834.1|WP_001295182.1|3065497_3066259_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>NZ_CP015834.1|WP_022646034.1|3074612_3074897_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMLVVVTENVPPRLRGRLAIWLLEVRAGVYVGDVSARIREMIWEQISGLAEEGNVVMAWATNTESGFEFQTFGVNRRTPVDLDGLRLVSFLPV
>NZ_CP015834.1|WP_022646035.1|3074898_3075816_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYVLLAKQYGVKWNGRRYDPKDWEKGDTVNQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS
>NZ_CP015834.1|WP_000281399.1|3075831_3076431_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKRNTPEGCHVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKRLDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSGDGKSGKIQTVCFEGVITINDAPALIDLVQQGIGPAKSMGCGLLSLAPL
>NZ_CP015834.1|WP_022646036.1|3076417_3077092_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCKASDPQKALLNYEPVGGDIYSEESVTGHYLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
>NZ_CP015834.1|WP_022646037.1|3077094_3078186_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSDYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKLVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMSELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGEA
>NZ_CP015834.1|WP_000752798.1|3078198_3078681_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MADEIDAMALYRAWQQLDNGACAQIRRVSEPDELRDIPAFYRLVQPFGWENPRHQQALLRMVFCLSAGKNVIRHQDKKPEQTTGISLGRALANSGRINERRIFQLIRADRTADMVQLRRLLTHAEPVLDWPLMARMLTWWGKRERQQLLEDFVLTTNKNA
>NZ_CP015834.1|WP_022646038.1|3078673_3080182_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNLLIDNWIPVRPRNGGEVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPITTFVCGIDLRSTVLLNVLTIPRLQKQFPNELHTENQPTWVKPVKPNESVPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANINFSQADEVIADLRDKLHQLCEMLFNQSEAPYAHHPKLISTLALARATLYKHLRELKPQGGPSNG
>NZ_CP015834.1|WP_022646039.1|3080596_3083263_-|CRISPR-associated-helicase/endonuclease-Cas3
MEPFKYICHYWGKSSKSLTKGNDIHLLIYHCLDVAAVADCWWEQSVVLQNAFCQNEMLSKQMVKAWLLFFIALHDIGKFDIRFQYKSAESWLKLNPATPSLNGPSTQMCRKFNHGAAGLYWFNQDSLSEQSPGDFFSFFDAAPHPYESWFPWVEAVTGHHGFILHSQDQDKSRWEMPASLASYAAQDKQAREEWISVLEALFLTPAGLSINDIPPDCSSLLAGFCSLADWLGSWTTTNTFLFKEDAPSNINALRTYFQDRQQDASRVLELSGLVSNKRCYEGVHALLDNGYQPRQLQVLVDALPAAPGLTVIEAPTGSGKTETALAYAWKLIDQQLADSVIFALPTQATANAMLSRMEANASRLFTSPNLILAHGNSRFNHLFQSIKSRAFTEQGQEEAWVQCCQWLSQSNKKVFLGQIGVCTIDQVLISVLPVKHRFIRGLGIGRSVLIVDEVHAYDTYMNGLLEAVLKAQADVGGSVILLSATLPMKQKQKLLDTYGLHTDPEENNSAYPLINWRGVNGAQRFDLLAHSEQLPPRFSIRPEPIYLADMLPDLRMLERMIVAANAGAQVCLICNLVDVAQLCHQRLKELNNTQVDIDLFHARFTLNDRREKENRVISNFGKNGKRNVGRILVATQVVEQSLDVDFDWLITQHCPADLLFQRLGRLHRHHRKYRPAGFEVPLASVLLPDGEGYGRHEHIYSNVRVMWRTQQHIEELNGASLFFPDAYRQWLDSIYDDAEMDEPEWVIKGMDKYESAECEKRFKARKVLQWAEEYSLQDNDETILAVTRDGEMSLPLLPYLQTSSGKQLLDGQVYEDLSHEQQYEALALNRVNVPFTWKRNFSEVVDEDGVLWLEGKQNQDGWIWQGNNIVITYTRDEGMTRVIPANPK
>NZ_CP015834.1|WP_022646040.1|3083621_3084356_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWNNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP015834.1|WP_001290706.1|3084429_3086142_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD

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Crispr_ID: NZ_CP015834_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015834_3

3100054-3101366

Unclear

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
GGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

21 spacers

The CRISPR arrays of NZ_CP015834_3

>merge|NZ_CP015834|3|3100054-3101366|CRISPRCasFinder,CRT,PILER-CR
TGGTTCATCCCCGCTGGCGCGGGGAACACGTCCTGTTTTTGACCGGCGGTAAATGTTGCCTGCGGTTTATCCCCGCTGGCGCGGGGAACACAATATCCGTTCCTCGCTCTGCGTTTTCGTTGACGGTTTATCCCCGCTGGCGCGGGGAACACGGTCGGGTATTTCATTATGCATCCTGAACTAACGGTTTATCCCCGCTGGCGCGGGGAACACTATGCGCTTGCTGCTGCGTTGATGTACGCGGCCGGTTTATCCCCGCTGGCGCGGGGAACACTTAACTACCTGAACACCGGGAAGACTCCGGACCGGTTTATCCCCGCTGGCGCGGGGAACACGATTCAATGTCCGACGCATCCAAGTAAATATTCGGTTTATCCCCGCTGGCGCGGGGAACACGGATGAGCAGGGAGCAACAAAAGTAGCCGGAATGGTTTATCCCCGCTGGCGCGGGGAACACCCATACATTAACACGGTGTGGCCACATTTCAACGGTTTATCCCCGCTGGCGCGGGGAACACGCGCGGCCGCGATATCGTTAGCACTGGCTCCCGCGGTTTATCCCCGCTGGCGCGGGGAACACCAAAACACCTGAACGTTGAGATAGGGCTAAATCGGTTTATCCCCGCTGGCGCGGGGAACACGTTGTCGTATTCCTTAGAAATCTGATGCCAGCCCGGTTTATCCCCGCTGGCGCGGGGAACACTGACTGACCGGGAAAAGAAAACACCTGGCGAACGGTTTATCCCCGCTGGCGCGGGGAACACAATTTTTCCAGTGGTGTCGTTGTAATTAAGGACGGTTTATCCCCGCTGGCGCGGGGAACACAGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGGCGGTTTATCCCCGCTGGCGCGGGGAACACATCCGTTAATTATTGAGAGAGCTATCAGCTATCGGTTTATCCCCGCTGGCGCGGGGAACACTCTAATTGCGCTTTGATAAATGGAGTTAAAGCCGGTTTATCCCCGCTGGCGCGGGGAACACGAATTCGGAATCACATTAAAAGGGAACCCGATAGGTTTATCCCCGCTGGCGCGGGGAACACCCAGGTCCCATTTGTCGATCGGCAGCGCCATTCGGTTTATCCCCGCTGGCGCGGGGAACACTGTTAATTCAGCAAGTTGAGATTGTGTCAGTCCGGTTTATCCCCGCTGGCGCGGGGAACACAAGAGAACAGCTTATATCTGATGCCGGTTTGCCGGTTTATCCCCGCTGGCGCGGGGAACACACACCGGCGAGATCGTATTTTTTGCCGCTGAGCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP015834|3|3|3100054-3101366|CRISPRCasFinder
TGGTTCATCCCCGCTGGCGCGGGGAACAC	GTCCTGTTTTTGACCGGCGGTAAATGTTGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATATCCGTTCCTCGCTCTGCGTTTTCGTTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGTCGGGTATTTCATTATGCATCCTGAACTAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TATGCGCTTGCTGCTGCGTTGATGTACGCGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTAACTACCTGAACACCGGGAAGACTCCGGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATTCAATGTCCGACGCATCCAAGTAAATATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATGAGCAGGGAGCAACAAAAGTAGCCGGAA
TGGTTTATCCCCGCTGGCGCGGGGAACAC	CCATACATTAACACGGTGTGGCCACATTTCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCGGCCGCGATATCGTTAGCACTGGCTCCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAACACCTGAACGTTGAGATAGGGCTAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTGTCGTATTCCTTAGAAATCTGATGCCAGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGACTGACCGGGAAAAGAAAACACCTGGCGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTTTCCAGTGGTGTCGTTGTAATTAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCCGTTAATTATTGAGAGAGCTATCAGCTAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTAATTGCGCTTTGATAAATGGAGTTAAAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTCGGAATCACATTAAAAGGGAACCCGAT
AGGTTTATCCCCGCTGGCGCGGGGAACAC	CCAGGTCCCATTTGTCGATCGGCAGCGCCATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGTTAATTCAGCAAGTTGAGATTGTGTCAGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAGAGAACAGCTTATATCTGATGCCGGTTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACACCGGCGAGATCGTATTTTTTGCCGCTGAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP015834|3|2|3100054-3101366|CRT
TGGTTCATCCCCGCTGGCGCGGGGAACAC	GTCCTGTTTTTGACCGGCGGTAAATGTTGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATATCCGTTCCTCGCTCTGCGTTTTCGTTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGTCGGGTATTTCATTATGCATCCTGAACTAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TATGCGCTTGCTGCTGCGTTGATGTACGCGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTAACTACCTGAACACCGGGAAGACTCCGGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATTCAATGTCCGACGCATCCAAGTAAATATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATGAGCAGGGAGCAACAAAAGTAGCCGGAA
TGGTTTATCCCCGCTGGCGCGGGGAACAC	CCATACATTAACACGGTGTGGCCACATTTCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCGGCCGCGATATCGTTAGCACTGGCTCCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAACACCTGAACGTTGAGATAGGGCTAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTGTCGTATTCCTTAGAAATCTGATGCCAGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGACTGACCGGGAAAAGAAAACACCTGGCGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTTTCCAGTGGTGTCGTTGTAATTAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCCGTTAATTATTGAGAGAGCTATCAGCTAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTAATTGCGCTTTGATAAATGGAGTTAAAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTCGGAATCACATTAAAAGGGAACCCGAT
AGGTTTATCCCCGCTGGCGCGGGGAACAC	CCAGGTCCCATTTGTCGATCGGCAGCGCCATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGTTAATTCAGCAAGTTGAGATTGTGTCAGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAGAGAACAGCTTATATCTGATGCCGGTTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACACCGGCGAGATCGTATTTTTTGCCGCTGAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP015834|3|2|3100055-3101366|PILER-CR
GGTTCATCCCCGCTGGCGCGGGGAACAC	GTCCTGTTTTTGACCGGCGGTAAATGTTGCCTGC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AATATCCGTTCCTCGCTCTGCGTTTTCGTTGAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GGTCGGGTATTTCATTATGCATCCTGAACTAAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TATGCGCTTGCTGCTGCGTTGATGTACGCGGCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TTAACTACCTGAACACCGGGAAGACTCCGGACC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GATTCAATGTCCGACGCATCCAAGTAAATATTC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GGATGAGCAGGGAGCAACAAAAGTAGCCGGAAT
GGTTTATCCCCGCTGGCGCGGGGAACAC	CCATACATTAACACGGTGTGGCCACATTTCAAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCGGCCGCGATATCGTTAGCACTGGCTCCCGC
GGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAACACCTGAACGTTGAGATAGGGCTAAATC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GTTGTCGTATTCCTTAGAAATCTGATGCCAGCCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TGACTGACCGGGAAAAGAAAACACCTGGCGAAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTTTCCAGTGGTGTCGTTGTAATTAAGGAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGGC
GGTTTATCCCCGCTGGCGCGGGGAACAC	ATCCGTTAATTATTGAGAGAGCTATCAGCTATC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TCTAATTGCGCTTTGATAAATGGAGTTAAAGCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTCGGAATCACATTAAAAGGGAACCCGATA
GGTTTATCCCCGCTGGCGCGGGGAACAC	CCAGGTCCCATTTGTCGATCGGCAGCGCCATTC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TGTTAATTCAGCAAGTTGAGATTGTGTCAGTCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AAGAGAACAGCTTATATCTGATGCCGGTTTGCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	ACACCGGCGAGATCGTATTTTTTGCCGCTGAGC
GGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015834.1\|WP_000109537.1\|3089961_3090222_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP015834.1\|WP_022646048.1\|3102670_3103543_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP015834.1\|WP_000581937.1\|3108050_3108299_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP015834.1\|WP_001071641.1\|3106852_3107644_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP015834.1\|WP_000046818.1\|3110658_3111960_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP015834.1\|WP_022646042.1\|3088699_3089971_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP015834.1\|WP_022646044.1\|3091817_3092597_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP015834.1\|WP_000021342.1\|3095529_3096315_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP015834.1\|WP_022646046.1\|3097937_3099416_+\|kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP015834.1\|WP_000210878.1\|3104987_3106625_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP015834.1\|WP_022646045.1\|3094005_3095460_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP015834.1\|WP_023908985.1\|3090960_3091821_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP015834.1\|WP_001130256.1\|3090238_3090814_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP015834.1\|WP_001164562.1\|3096633_3097911_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP015834.1\|WP_000254750.1\|3107715_3108051_-\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP015834.1\|WP_000147668.1\|3092574_3093984_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP015834.1\|WP_001199973.1\|3101705_3102377_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP015834.1\|WP_000036723.1\|3103602_3104901_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP015834.1\|WP_000226815.1\|3108376_3110611_-\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP015834.1\|WP_000186450.1\|3112016_3114773_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848

Protein	Function_ID	Function_description	E-value
NZ_CP015834.1\|WP_000109537.1\|3089961_3090222_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	3.07968e-40
NZ_CP015834.1\|WP_022646048.1\|3102670_3103543_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	2.57168e-95
NZ_CP015834.1\|WP_000581937.1\|3108050_3108299_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP015834.1\|WP_001071641.1\|3106852_3107644_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	6.52379e-160
NZ_CP015834.1\|WP_000046818.1\|3110658_3111960_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP015834.1\|WP_022646042.1\|3088699_3089971_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	3.94463e-124
NZ_CP015834.1\|WP_022646044.1\|3091817_3092597_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	4.70543e-60
NZ_CP015834.1\|WP_000021342.1\|3095529_3096315_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	8.62537e-140
NZ_CP015834.1\|WP_022646046.1\|3097937_3099416_+\|kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	8.58462e-109
NZ_CP015834.1\|WP_000210878.1\|3104987_3106625_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP015834.1\|WP_022646045.1\|3094005_3095460_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.79726e-81
NZ_CP015834.1\|WP_023908985.1\|3090960_3091821_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	2.43837e-88
NZ_CP015834.1\|WP_001130256.1\|3090238_3090814_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	1.33799e-87
NZ_CP015834.1\|WP_001164562.1\|3096633_3097911_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.87501e-29
NZ_CP015834.1\|WP_000254750.1\|3107715_3108051_-\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.22533e-74
NZ_CP015834.1\|WP_000147668.1\|3092574_3093984_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.9507e-51
NZ_CP015834.1\|WP_001199973.1\|3101705_3102377_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP015834.1\|WP_000036723.1\|3103602_3104901_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP015834.1\|WP_000226815.1\|3108376_3110611_-\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP015834.1\|WP_000186450.1\|3112016_3114773_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0

>NZ_CP015834.1|WP_022646046.1|3097937_3099416_+|kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKTWAWSEDAAVMEKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFMPVESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNEDSIQSWSNA
>NZ_CP015834.1|WP_001164562.1|3096633_3097911_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIIFTFLLFQKIRTADSAPAMASSK
>NZ_CP015834.1|WP_000021342.1|3095529_3096315_-|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP015834.1|WP_022646045.1|3094005_3095460_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDVEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNHLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWTLLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP015834.1|WP_000147668.1|3092574_3093984_-|MFS-transporter
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP015834.1|WP_022646044.1|3091817_3092597_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGNIGPDVSLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEDAVLLETVADLRFAPEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFITLEQRTENGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAAIIRKTVAVELPAMQCLHLARAEQRRGATLIDGQTVAEKAQKLWQNYLRQRMQP
>NZ_CP015834.1|WP_023908985.1|3090960_3091821_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTDKRPLCLSLARQAGADKNATLPSGMQQLNIVPGALPDWLVSLENLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVCNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEAMVTNIHADCQ
>NZ_CP015834.1|WP_001130256.1|3090238_3090814_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISHIVKKIKSAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP015834.1|WP_000109537.1|3089961_3090222_+|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTVQWLINACPAGLFSLTPEGDLRIDYRSCLECGTCRLLCDEKTLQQWRYPPSGFGITYRFG
>NZ_CP015834.1|WP_022646042.1|3088699_3089971_+|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTQALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRACYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLLGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL
>NZ_CP015834.1|WP_001199973.1|3101705_3102377_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP015834.1|WP_022646048.1|3102670_3103543_+|YgcG-family-protein
MRYFILIFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTRKLESIFNNTQVQIAVLIIPTTKDETIEQYATRVFNNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAKGLELAIIALNNQLTSQHQYSANPSESESASSSDYYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDLFLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKKASGRSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>NZ_CP015834.1|WP_000036723.1|3103602_3104901_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP015834.1|WP_000210878.1|3104987_3106625_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP015834.1|WP_001071641.1|3106852_3107644_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEAQQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP015834.1|WP_000254750.1|3107715_3108051_-|endoribonuclease-MazF
MVSRYVPDTGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP015834.1|WP_000581937.1|3108050_3108299_-|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP015834.1|WP_000226815.1|3108376_3110611_-|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP015834.1|WP_000046818.1|3110658_3111960_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLECFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLHNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP015834.1|WP_000186450.1|3112016_3114773_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG

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Crispr_ID: NZ_CP015834_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015834_4

4973747-4973881

Orphan

Consensus_repeat	Method
GTGCTGTGTAGGTCGGATAAGGCGTTCATGCCGCATCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015834_4

>merge|NZ_CP015834|4|4973747-4973881|CRISPRCasFinder
GTGCTGTGTAGGTCGGATAAGGCGTTCATGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTGCCGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCACGCCGCATCCG

>NZ_CP015834|4|4|4973747-4973881|CRISPRCasFinder
GTGCTGTGTAGGTCGGATAAGGCGTTCATGCCGCATCCG	ACAATAACAGCATTGCCTGATGCGACGCTGCCGCGTCTTATCAGGCCTACGAGTTCA
GTGCTGTGTAGGTCGGATAAGGCGTTCACGCCGCATCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015834.1\|WP_069383069.1\|4980672_4981992_-\|gnt-II-system-L-idonate-transporter	unknown	unknown	gnl\|CDD\|129873
NZ_CP015834.1\|WP_001294573.1\|4978027_4979530_-\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP015834.1\|WP_000079641.1\|4969100_4970297_+\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP015834.1\|WP_001295681.1\|4976784_4977867_+\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP015834.1\|WP_001309160.1\|4984656_4985676_-\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP015834.1\|WP_001353502.1\|4964540_4964993_+\|toxin-antitoxin-biofilm-protein-TabA	unknown	unknown	gnl\|CDD\|225345
NZ_CP015834.1\|WP_000786399.1\|4973207_4973651_-\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP015834.1\|WP_001309158.1\|4966445_4966676_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015834.1\|WP_000584114.1\|4975684_4976785_+\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP015834.1\|WP_000397144.1\|4973906_4975418_-\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP015834.1\|WP_001309159.1\|4979607_4980606_-\|DNA-binding-transcriptional-regulator-IdnR	unknown	unknown	gnl\|CDD\|380489
NZ_CP015834.1\|WP_001197411.1\|4982841_4983873_-\|L-idonate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|182130
NZ_CP015834.1\|WP_000012907.1\|4966776_4967781_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP015834.1\|WP_000896738.1\|4984089_4984653_+\|gluconokinase	unknown	unknown	gnl\|CDD\|182097
NZ_CP015834.1\|WP_001309157.1\|4966105_4966459_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015834.1\|WP_000998695.1\|4982053_4982818_-\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|181225
NZ_CP015834.1\|WP_001059422.1\|4968404_4968908_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP015834.1\|WP_000416382.1\|4970352_4973208_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP015834.1\|WP_000002953.1\|4967942_4968359_+\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP015834.1\|WP_000036525.1\|4965115_4966090_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP015834.1\|WP_069383069.1\|4980672_4981992_-\|gnt-II-system-L-idonate-transporter	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP015834.1\|WP_001294573.1\|4978027_4979530_-\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP015834.1\|WP_000079641.1\|4969100_4970297_+\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	1.34664e-150
NZ_CP015834.1\|WP_001353502.1\|4964540_4964993_+\|toxin-antitoxin-biofilm-protein-TabA	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	2.33363e-69
NZ_CP015834.1\|WP_000786399.1\|4973207_4973651_-\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NZ_CP015834.1\|WP_000584114.1\|4975684_4976785_+\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP015834.1\|WP_001295681.1\|4976784_4977867_+\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP015834.1\|WP_001309159.1\|4979607_4980606_-\|DNA-binding-transcriptional-regulator-IdnR	gnl\|CDD\|380489	cd01575, PBP1_GntR, ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. This group represents the ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of GntR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding, which in turn changes the DNA binding affinity of the repressor.	1.4437e-109
NZ_CP015834.1\|WP_001197411.1\|4982841_4983873_-\|L-idonate-5-dehydrogenase	gnl\|CDD\|182130	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional.	0
NZ_CP015834.1\|WP_000012907.1\|4966776_4967781_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP015834.1\|WP_000896738.1\|4984089_4984653_+\|gluconokinase	gnl\|CDD\|182097	PRK09825, idnK, gluconokinase.	1.3617e-126
NZ_CP015834.1\|WP_000397144.1\|4973906_4975418_-\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP015834.1\|WP_000998695.1\|4982053_4982818_-\|gluconate-5-dehydrogenase	gnl\|CDD\|181225	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional.	0
NZ_CP015834.1\|WP_001059422.1\|4968404_4968908_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.57543e-19
NZ_CP015834.1\|WP_001309160.1\|4984656_4985676_-\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.21683e-169
NZ_CP015834.1\|WP_000002953.1\|4967942_4968359_+\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
NZ_CP015834.1\|WP_000416382.1\|4970352_4973208_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0

>NZ_CP015834.1|WP_000786399.1|4973207_4973651_-|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP015834.1|WP_000416382.1|4970352_4973208_-|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP015834.1|WP_000079641.1|4969100_4970297_+|DUF898-domain-containing-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFCYFAILMTVSADMPLVGCVLTLLLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGFWWVTFFLPILMAIGMGTVFFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLARISRGIMPSLPFL
>NZ_CP015834.1|WP_001059422.1|4968404_4968908_-|GNAT-family-N-acetyltransferase
MNNIAPQSPVMRRLTQQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYDGEVVGGGGIAPLTGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCEVRMLREL
>NZ_CP015834.1|WP_000002953.1|4967942_4968359_+|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP015834.1|WP_000012907.1|4966776_4967781_-|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
>NZ_CP015834.1|WP_001309158.1|4966445_4966676_+|hypothetical-protein
MKQPDFAKWYFYQLLKDYEGEQLYLNELGYVYGNEEKTNEIVKNNPGYVVKIFEEKMVNELKIRTRMMKILRKIYV
>NZ_CP015834.1|WP_001309157.1|4966105_4966459_+|hypothetical-protein
MQYFGDSEKIKYACSVINHIDFSRDQSKDFSCDQSKIKIAETLFFNLDKEHYKNSRKLQELIWDKLVAYVNDFNLSNQEKSRLILRLFDDVKLLFNEVPVSILVNDIFFEGFFHEAT
>NZ_CP015834.1|WP_000036525.1|4965115_4966090_+|hypothetical-protein
MSKISGWNFSQNITSADNCKQKNEDLDTWYVGMNDFARIAGGQNSRSNILSPRAFLEFLAKIFTLGYVDFSKRSNEAGRNMMAHIKSSSYIKNNDGSEIMKFVMNNPEGERADLSKVEIEITLASAFNNGIREGHTVIIFTQPDGSTNRYEGKSFERKDESSLHLITNKILACYQREANKEIARLLNIPQELNNSQDLNNSQVSCKDSVDSTITDLLEKPLNNALLAIRKEHLLLMPYVCNESISYLLGEKGILKEIDDLNAVNNYLLNNKKATDNEINDIKVNLSHILIDSLDDAKVNLTPVIDSILEIFLKFPYINDVRILD
>NZ_CP015834.1|WP_001353502.1|4964540_4964993_+|toxin-antitoxin-biofilm-protein-TabA
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTRDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP015834.1|WP_000397144.1|4973906_4975418_-|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP015834.1|WP_000584114.1|4975684_4976785_+|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP015834.1|WP_001295681.1|4976784_4977867_+|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP015834.1|WP_001294573.1|4978027_4979530_-|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGVAQAGTVSEKLLARLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP015834.1|WP_001309159.1|4979607_4980606_-|DNA-binding-transcriptional-regulator-IdnR
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL
>NZ_CP015834.1|WP_069383069.1|4980672_4981992_-|gnt-II-system-L-idonate-transporter
MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGLPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
>NZ_CP015834.1|WP_000998695.1|4982053_4982818_-|gluconate-5-dehydrogenase
MNDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV
>NZ_CP015834.1|WP_001197411.1|4982841_4983873_-|L-idonate-5-dehydrogenase
MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF
>NZ_CP015834.1|WP_000896738.1|4984089_4984653_+|gluconokinase
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGSASDQRCE
>NZ_CP015834.1|WP_001309160.1|4984656_4985676_-|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF

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Crispr_ID: NZ_CP015834_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015834_5

5142427-5142591

Orphan

Consensus_repeat	Method
CTAACGTGCAGGTTTTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACACGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015834_5

>merge|NZ_CP015834|5|5142427-5142591|CRISPRCasFinder
CTAACGTGCAGGTTTTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACACGGTATTTGGGTGCAGATGCCAGATGCGACGCGGGCGCGCCTTATCTGGCCTACGAAGGGCTAACGTGCAGGTTTGGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACACGG

>NZ_CP015834|5|5|5142427-5142591|CRISPRCasFinder
CTAACGTGCAGGTTTTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACACGG	TATTTGGGTGCAGATGCCAGATGCGACGCGGGCGCGCCTTATCTGGCCTACGAAGGG
CTAACGTGCAGGTTTGGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACACGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015834.1\|WP_001272335.1\|5142684_5143716_-\|16S-rRNA-(guanine(1207)-N(2))-methyltransferase-RsmC	unknown	unknown	gnl\|CDD\|181902
NZ_CP015834.1\|WP_001422893.1\|5141708_5141945_+\|DUF1435-domain-containing-protein	unknown	unknown	gnl\|CDD\|369291
NZ_CP015834.1\|WP_000870712.1\|5144661_5145339_+\|pyrimidine-5'-nucleotidase	unknown	unknown	gnl\|CDD\|181865
NZ_CP015834.1\|WP_001088430.1\|5150498_5151362_-\|YjjW-family-glycine-radical-enzyme-activase	unknown	unknown	gnl\|CDD\|274938
NZ_CP015834.1\|WP_001092461.1\|5144200_5144647_+\|ribosomal-protein-S18-alanine-N-acetyltransferase	unknown	unknown	gnl\|CDD\|181904
NZ_CP015834.1\|WP_001295748.1\|5147411_5148017_+\|molecular-chaperone-OsmY	unknown	unknown	gnl\|CDD\|182556
NZ_CP015834.1\|WP_000204018.1\|5143818_5144232_+\|DNA-polymerase-III-subunit-psi	unknown	unknown	gnl\|CDD\|180735
NZ_CP015834.1\|WP_001385581.1\|5148427_5149501_+\|patatin-family-protein	unknown	unknown	gnl\|CDD\|227013
NZ_CP015834.1\|WP_000175940.1\|5145429_5147019_+\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NZ_CP015834.1\|WP_000490275.1\|5148145_5148307_+\|DUF1328-domain-containing-protein	unknown	unknown	gnl\|CDD\|227774
NZ_CP015834.1\|WP_001376704.1\|5137992_5138763_-\|threonine/serine-exporter-ThrE-family-protein	unknown	unknown	gnl\|CDD\|225514
NZ_CP015834.1\|WP_001305619.1\|5135599_5136094_-\|DUF2501-domain-containing-protein	unknown	unknown	gnl\|CDD\|236951
NZ_CP015834.1\|WP_000799911.1\|5136142_5136880_-\|DNA-replication-protein-DnaC	unknown	unknown	gnl\|CDD\|181180
NZ_CP015834.1\|WP_000331576.1\|5140779_5141568_-\|siderophore-iron-reductase-FhuF	unknown	unknown	gnl\|CDD\|182616
NZ_CP015834.1\|WP_000098815.1\|5136882_5137422_-\|primosomal-protein-DnaT	unknown	unknown	gnl\|CDD\|179484
NZ_CP015834.1\|WP_000936635.1\|5139381_5140107_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP015834.1\|WP_001309201.1\|5140064_5140742_+\|DNA-binding-transcriptional-activator-BglJ	unknown	unknown	gnl\|CDD\|236915
NZ_CP015834.1\|WP_022646477.1\|5149497_5150280_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|171118
NZ_CP015834.1\|WP_000538191.1\|5137528_5138002_-\|threonine/serine-exporter	unknown	unknown	gnl\|CDD\|182143
NZ_CP015834.1\|WP_001292674.1\|5133054_5135346_-\|phosphatidylglycerol--membrane-oligosaccharide-glycerophosphotransferase	unknown	unknown	gnl\|CDD\|179648

Protein	Function_ID	Function_description	E-value
NZ_CP015834.1\|WP_001272335.1\|5142684_5143716_-\|16S-rRNA-(guanine(1207)-N(2))-methyltransferase-RsmC	gnl\|CDD\|181902	PRK09489, rsmC, 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC.	0
NZ_CP015834.1\|WP_001422893.1\|5141708_5141945_+\|DUF1435-domain-containing-protein	gnl\|CDD\|369291	pfam07256, DUF1435, Protein of unknown function (DUF1435). This family consists of several hypothetical Enterobacterial proteins of around 80 residues in length. The function of this family is unknown.	1.64081e-26
NZ_CP015834.1\|WP_000870712.1\|5144661_5145339_+\|pyrimidine-5'-nucleotidase	gnl\|CDD\|181865	PRK09449, PRK09449, dUMP phosphatase; Provisional.	8.3853e-174
NZ_CP015834.1\|WP_001088430.1\|5150498_5151362_-\|YjjW-family-glycine-radical-enzyme-activase	gnl\|CDD\|274938	TIGR04041, glycine_radical_enzyme_activase_YjjW_family, glycine radical enzyme activase, YjjW family. Members of this family are radical SAM enzymes, designated YjjW in E. coli, that are paired with and appear to activate a glycyl radical enzyme of unknown function, designated YjjI. This activase and its target are found in Clostridial species as well as E. coli and cousins. Members of this family may be misannotated as pyruvate formate lyase activating enzyme. [Protein fate, Protein modification and repair].	6.64188e-163
NZ_CP015834.1\|WP_001092461.1\|5144200_5144647_+\|ribosomal-protein-S18-alanine-N-acetyltransferase	gnl\|CDD\|181904	PRK09491, rimI, ribosomal-protein-alanine N-acetyltransferase; Provisional.	1.40837e-111
NZ_CP015834.1\|WP_001295748.1\|5147411_5148017_+\|molecular-chaperone-OsmY	gnl\|CDD\|182556	PRK10568, PRK10568, molecular chaperone OsmY.	4.36119e-102
NZ_CP015834.1\|WP_000204018.1\|5143818_5144232_+\|DNA-polymerase-III-subunit-psi	gnl\|CDD\|180735	PRK06856, PRK06856, DNA polymerase III subunit psi; Validated.	5.48557e-70
NZ_CP015834.1\|WP_001385581.1\|5148427_5149501_+\|patatin-family-protein	gnl\|CDD\|227013	COG4667, COG4667, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only].	1.02103e-167
NZ_CP015834.1\|WP_000175940.1\|5145429_5147019_+\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NZ_CP015834.1\|WP_000490275.1\|5148145_5148307_+\|DUF1328-domain-containing-protein	gnl\|CDD\|227774	COG5487, COG5487, Small integral membrane protein [Function unknown].	4.97087e-08
NZ_CP015834.1\|WP_001376704.1\|5137992_5138763_-\|threonine/serine-exporter-ThrE-family-protein	gnl\|CDD\|225514	COG2966, COG2966, Uncharacterized conserved protein [Function unknown].	3.2051e-97
NZ_CP015834.1\|WP_001305619.1\|5135599_5136094_-\|DUF2501-domain-containing-protein	gnl\|CDD\|236951	PRK11667, PRK11667, hypothetical protein; Provisional.	4.66508e-71
NZ_CP015834.1\|WP_000799911.1\|5136142_5136880_-\|DNA-replication-protein-DnaC	gnl\|CDD\|181180	PRK07952, PRK07952, DNA replication protein DnaC; Validated.	2.89557e-176
NZ_CP015834.1\|WP_000331576.1\|5140779_5141568_-\|siderophore-iron-reductase-FhuF	gnl\|CDD\|182616	PRK10647, PRK10647, ferric iron reductase involved in ferric hydroximate transport; Provisional.	4.21041e-176
NZ_CP015834.1\|WP_000098815.1\|5136882_5137422_-\|primosomal-protein-DnaT	gnl\|CDD\|179484	PRK02854, PRK02854, primosomal protein DnaT.	6.32406e-124
NZ_CP015834.1\|WP_000936635.1\|5139381_5140107_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.97362e-26
NZ_CP015834.1\|WP_001309201.1\|5140064_5140742_+\|DNA-binding-transcriptional-activator-BglJ	gnl\|CDD\|236915	PRK11475, PRK11475, DNA-binding transcriptional activator BglJ; Provisional.	8.38273e-127
NZ_CP015834.1\|WP_022646477.1\|5149497_5150280_+\|metal-dependent-hydrolase	gnl\|CDD\|171118	PRK11449, PRK11449, metal-dependent hydrolase.	3.83975e-179
NZ_CP015834.1\|WP_000538191.1\|5137528_5138002_-\|threonine/serine-exporter	gnl\|CDD\|182143	PRK09917, PRK09917, threonine/serine exporter.	4.73594e-99
NZ_CP015834.1\|WP_001292674.1\|5133054_5135346_-\|phosphatidylglycerol--membrane-oligosaccharide-glycerophosphotransferase	gnl\|CDD\|179648	PRK03776, PRK03776, phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.	0

>NZ_CP015834.1|WP_001422893.1|5141708_5141945_+|DUF1435-domain-containing-protein
MLQRTLGSGWGVLLPGLLIAGLMYADLSPDQWRIVILMGLILTPVMLYHKQLRHYVLLPSCLALIAGIMLMIMNLNQG
>NZ_CP015834.1|WP_000331576.1|5140779_5141568_-|siderophore-iron-reductase-FhuF
MAYRSAPLYEDVIWRTHLQPQDAGLAQAIRATIAEHREHLLEFIRLDEPAPLNAMTLAQWSSTNALSSLLVVYSDHIYRNQPTMIRENKPLISLWAQWYIGLMVPPLMLALLTQEKALDVSPEHFHVEFHETGRAACFWVDVCEDKNATLHSPQQRMETLISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKMLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCMLK
>NZ_CP015834.1|WP_001309201.1|5140064_5140742_+|DNA-binding-transcriptional-activator-BglJ
MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQESFQDAMSRISFAAVIFSFSAMRGERREGLSCLTELAIKFPRTRRLVIADDDIEARLIGSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREILRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEASNVLHPY
>NZ_CP015834.1|WP_000936635.1|5139381_5140107_+|response-regulator-transcription-factor
MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDLTLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLMCPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERKVLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELNLPSVYGDAAEWNTAELRREMSHS
>NZ_CP015834.1|WP_001376704.1|5137992_5138763_-|threonine/serine-exporter-ThrE-family-protein
MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMDSVESSISSNAIVLTTIKDGQCLTSTRKNQDRGINMHVVTEVQHIVILAEHHLLDYKGVEKRFSQIQPLRYPRWLVALMVGLSCACFCKLNKGGWDGAVITFFASTVAMYIRQLLAQRHLHPQINFCLTAFAATTISGLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMFKGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV
>NZ_CP015834.1|WP_000538191.1|5137528_5138002_-|threonine/serine-exporter
MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGSIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
>NZ_CP015834.1|WP_000098815.1|5136882_5137422_-|primosomal-protein-DnaT
MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFIRLAALWGVALRAPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPKRDVNTVSEPDSQIPPGFRG
>NZ_CP015834.1|WP_000799911.1|5136142_5136880_-|DNA-replication-protein-DnaC
MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAALERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDLSNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVMDRMRLGNSLWVIFNWDSYRSRVTGKEY
>NZ_CP015834.1|WP_001305619.1|5135599_5136094_-|DUF2501-domain-containing-protein
MMKTVKHLLCCAIAASALISTGAHAASWKDALSSAASELGNQNNTTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLEKLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGLNFIS
>NZ_CP015834.1|WP_001292674.1|5133054_5135346_-|phosphatidylglycerol--membrane-oligosaccharide-glycerophosphotransferase
MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRRHHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKTTWKGKTAFKDTVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG
>NZ_CP015834.1|WP_001272335.1|5142684_5143716_-|16S-rRNA-(guanine(1207)-N(2))-methyltransferase-RsmC
MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSRQMGDNARFSLVATADDVADCNTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPEFDADKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
>NZ_CP015834.1|WP_000204018.1|5143818_5144232_+|DNA-polymerase-III-subunit-psi
MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVANDLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQVASPALTELRANPTARAALWQQICTYEHDFFPRND
>NZ_CP015834.1|WP_001092461.1|5144200_5144647_+|ribosomal-protein-S18-alanine-N-acetyltransferase
MNTISSLETTDLPAAYHIEQRAHAFPWSEKTFASNQGERYLNFQLTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM
>NZ_CP015834.1|WP_000870712.1|5144661_5145339_+|pyrimidine-5'-nucleotidase
MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVSLLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYALEQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHNREQPEGIAPTWTVSSLHELEQLLCKH
>NZ_CP015834.1|WP_000175940.1|5145429_5147019_+|peptide-chain-release-factor-3
MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
>NZ_CP015834.1|WP_001295748.1|5147411_5148017_+|molecular-chaperone-OsmY
MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVDSSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEAVKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVETTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK
>NZ_CP015834.1|WP_000490275.1|5148145_5148307_+|DUF1328-domain-containing-protein
MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLVSLFMGRKRP
>NZ_CP015834.1|WP_001385581.1|5148427_5149501_+|patatin-family-protein
MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLDEFMRAQFNPFDLYLGTSAGAQNLSAYICNQPGYARKVIMRYTTKREFFDPLRFVRGGNLIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVIRASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQWFKRMERWLGDSSLQPLVNLVQHHETSYREIQQFIEKPPGQLRIFEIYPPKPLHSIALGSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVTPESIVIPPAPVANDTLVTEVIDAPQANDPTFNNEDLA
>NZ_CP015834.1|WP_022646477.1|5149497_5150280_+|metal-dependent-hydrolase
MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAANFARVLALAENYQPLYASLGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDLFGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRQNLPRTGVVHGFSGSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASMLLETDAPDMPLNGFQGQPNRPEQAARVFAVLCELRPEPADEIAEVLLNNTYAVFNVRG
>NZ_CP015834.1|WP_001088430.1|5150498_5151362_-|YjjW-family-glycine-radical-enzyme-activase
MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTMGRCNDCGECVPQCPHQALQIVNSKVVWNAAVCEQCDTCLKMCPQHATPMAQSMNVDEVLSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLCHLTCLVDSNGMLSETGWEKLLPVCDGAMLDLKAWGGACHQQLTGRDNQQIKRSISLLAERGKLAELRLLVIPGHVDYLQHIDELAAFIKGLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEQLADALREHGVSRLIFPALYL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP015834_3	3.7\|3100450\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100450-3100481	32	NZ_CP015834.1	3121167-3121198	1	0.969
NZ_CP015834_3	3.28\|3100450\|33\|NZ_CP015834\|PILER-CR	3100450-3100482	33	NZ_CP015834.1	3121166-3121198	1	0.97

1. spacer 3.7|3100450|32|NZ_CP015834|CRISPRCasFinder,CRT matches to position: 3121167-3121198, mismatch: 1, identity: 0.969

ggatgagcagggagcaacaaaagtagccggaa	CRISPR spacer
ggatgagcagggagcaacaaaagtagctggaa	Protospacer
***************************.****

2. spacer 3.28|3100450|33|NZ_CP015834|PILER-CR matches to position: 3121166-3121198, mismatch: 1, identity: 0.97

ggatgagcagggagcaacaaaagtagccggaat	CRISPR spacer
ggatgagcagggagcaacaaaagtagctggaat	Protospacer
***************************.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015834_2	2.1\|3073653\|32\|NZ_CP015834\|CRT	3073653-3073684	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	3	0.906
NZ_CP015834_2	2.5\|3073898\|32\|NZ_CP015834\|CRT,CRISPRCasFinder,PILER-CR	3073898-3073929	32	MF547662	Clostridioides phage LIBA6276, complete genome	37369-37400	4	0.875
NZ_CP015834_2	2.5\|3073898\|32\|NZ_CP015834\|CRT,CRISPRCasFinder,PILER-CR	3073898-3073929	32	MF547663	Clostridioides phage LIBA2945, complete genome	37369-37400	4	0.875
NZ_CP015834_2	2.5\|3073898\|32\|NZ_CP015834\|CRT,CRISPRCasFinder,PILER-CR	3073898-3073929	32	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	83504-83535	5	0.844
NZ_CP015834_2	2.13\|3074386\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074386-3074417	32	MK972713	Salmonella phage SW5, complete genome	27687-27718	5	0.844
NZ_CP015834_2	2.13\|3074386\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074386-3074417	32	MK972714	Salmonella phage SW3, complete genome	27909-27940	5	0.844
NZ_CP015834_2	2.13\|3074386\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074386-3074417	32	NC_049460	Salmonella phage SI7, complete genome	18129-18160	5	0.844
NZ_CP015834_2	2.22\|3074387\|32\|NZ_CP015834\|PILER-CR	3074387-3074418	32	MK972713	Salmonella phage SW5, complete genome	27687-27718	5	0.844
NZ_CP015834_2	2.22\|3074387\|32\|NZ_CP015834\|PILER-CR	3074387-3074418	32	MK972714	Salmonella phage SW3, complete genome	27909-27940	5	0.844
NZ_CP015834_2	2.22\|3074387\|32\|NZ_CP015834\|PILER-CR	3074387-3074418	32	NC_049460	Salmonella phage SI7, complete genome	18129-18160	5	0.844
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1203814-1203845	6	0.812
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1167510-1167541	6	0.812
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1203814-1203845	6	0.812
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1167510-1167541	6	0.812
NZ_CP015834_2	2.1\|3073653\|32\|NZ_CP015834\|CRT	3073653-3073684	32	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	112768-112799	7	0.781
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1175642-1175673	7	0.781
NZ_CP015834_2	2.14\|3074447\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074447-3074478	32	LR597649	Escherichia phage ESSI2_ev015 genome assembly, chromosome: 1	17850-17881	7	0.781
NZ_CP015834_2	2.14\|3074447\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074447-3074478	32	NC_049393	Escherichia phage ESSI2_ev040 genome assembly, chromosome: 1	17628-17659	7	0.781
NZ_CP015834_2	2.14\|3074447\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074447-3074478	32	NC_049394	Escherichia phage ESSI2_ev129 genome assembly, chromosome: 1	17890-17921	7	0.781
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1175642-1175673	7	0.781
NZ_CP015834_2	2.23\|3074448\|32\|NZ_CP015834\|PILER-CR	3074448-3074479	32	LR597649	Escherichia phage ESSI2_ev015 genome assembly, chromosome: 1	17850-17881	7	0.781
NZ_CP015834_2	2.23\|3074448\|32\|NZ_CP015834\|PILER-CR	3074448-3074479	32	NC_049393	Escherichia phage ESSI2_ev040 genome assembly, chromosome: 1	17628-17659	7	0.781
NZ_CP015834_2	2.23\|3074448\|32\|NZ_CP015834\|PILER-CR	3074448-3074479	32	NC_049394	Escherichia phage ESSI2_ev129 genome assembly, chromosome: 1	17890-17921	7	0.781
NZ_CP015834_3	3.18\|3101123\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3101123-3101154	32	NC_018022	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence	373536-373567	7	0.781
NZ_CP015834_2	2.1\|3073653\|32\|NZ_CP015834\|CRT	3073653-3073684	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1428097-1428128	8	0.75
NZ_CP015834_2	2.7\|3074020\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074020-3074051	32	NZ_CP008818	Ochrobactrum anthropi strain OAB plasmid 2, complete sequence	52227-52258	8	0.75
NZ_CP015834_2	2.7\|3074020\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074020-3074051	32	NC_009671	Ochrobactrum anthropi ATCC 49188 plasmid pOANT03, complete sequence	23638-23669	8	0.75
NZ_CP015834_2	2.9\|3074142\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074142-3074173	32	MN694482	Marine virus AFVG_250M11, complete genome	1728-1759	8	0.75
NZ_CP015834_2	2.10\|3074203\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074203-3074234	32	NZ_CP024236	Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence	57083-57114	8	0.75
NZ_CP015834_2	2.11\|3074264\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074264-3074295	32	CP022610	Escherichia coli strain ATCC 700415 plasmid unnamed, complete sequence	10541-10572	8	0.75
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NC_031109	Gordonia phage Jumbo, complete genome	25391-25422	8	0.75
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NZ_CP050093	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence	398774-398805	8	0.75
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NC_008384	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence	565533-565564	8	0.75
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NZ_CP042332	Bosea sp. F3-2 plasmid pB32-1, complete sequence	63515-63546	8	0.75
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	350647-350678	8	0.75
NZ_CP015834_2	2.16\|3074021\|32\|NZ_CP015834\|PILER-CR	3074021-3074052	32	NZ_CP008818	Ochrobactrum anthropi strain OAB plasmid 2, complete sequence	52227-52258	8	0.75
NZ_CP015834_2	2.16\|3074021\|32\|NZ_CP015834\|PILER-CR	3074021-3074052	32	NC_009671	Ochrobactrum anthropi ATCC 49188 plasmid pOANT03, complete sequence	23638-23669	8	0.75
NZ_CP015834_2	2.18\|3074143\|32\|NZ_CP015834\|PILER-CR	3074143-3074174	32	MN694482	Marine virus AFVG_250M11, complete genome	1728-1759	8	0.75
NZ_CP015834_2	2.19\|3074204\|32\|NZ_CP015834\|PILER-CR	3074204-3074235	32	NZ_CP024236	Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence	57083-57114	8	0.75
NZ_CP015834_2	2.20\|3074265\|32\|NZ_CP015834\|PILER-CR	3074265-3074296	32	CP022610	Escherichia coli strain ATCC 700415 plasmid unnamed, complete sequence	10541-10572	8	0.75
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NC_031109	Gordonia phage Jumbo, complete genome	25391-25422	8	0.75
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NZ_CP050093	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence	398774-398805	8	0.75
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NC_008384	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence	565533-565564	8	0.75
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NZ_CP042332	Bosea sp. F3-2 plasmid pB32-1, complete sequence	63515-63546	8	0.75
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	350647-350678	8	0.75
NZ_CP015834_3	3.4\|3100267\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100267-3100298	32	MN855615	Siphoviridae sp. isolate 320, complete genome	7076-7107	8	0.75
NZ_CP015834_3	3.4\|3100267\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100267-3100298	32	NC_034248	Rhizobium phage RHEph10, complete genome	31444-31475	8	0.75
NZ_CP015834_3	3.9\|3100572\|33\|NZ_CP015834\|CRISPRCasFinder,CRT	3100572-3100604	33	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	413541-413573	8	0.758
NZ_CP015834_3	3.13\|3100818\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100818-3100849	32	NC_013085	Synechococcus phage S-RSM4, complete genome	75536-75567	8	0.75
NZ_CP015834_3	3.13\|3100818\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100818-3100849	32	FM207411	Synechococcus phage S-RSM4 complete genome	75536-75567	8	0.75
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	405764-405795	8	0.75
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NZ_CP053710	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence	354033-354064	8	0.75
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NZ_CP053712	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence	91487-91518	8	0.75
NZ_CP015834_1	1.2\|1016159\|32\|NZ_CP015834\|CRISPRCasFinder	1016159-1016190	32	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9736-9767	9	0.719
NZ_CP015834_1	1.2\|1016159\|32\|NZ_CP015834\|CRISPRCasFinder	1016159-1016190	32	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9737-9768	9	0.719
NZ_CP015834_1	1.2\|1016159\|32\|NZ_CP015834\|CRISPRCasFinder	1016159-1016190	32	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9736-9767	9	0.719
NZ_CP015834_2	2.1\|3073653\|32\|NZ_CP015834\|CRT	3073653-3073684	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	141278-141309	9	0.719
NZ_CP015834_2	2.5\|3073898\|32\|NZ_CP015834\|CRT,CRISPRCasFinder,PILER-CR	3073898-3073929	32	MN693584	Marine virus AFVG_25M163, complete genome	29591-29622	9	0.719
NZ_CP015834_2	2.5\|3073898\|32\|NZ_CP015834\|CRT,CRISPRCasFinder,PILER-CR	3073898-3073929	32	MN103543	Pseudomonas phage vB_PaeM_PS119XW, complete genome	258501-258532	9	0.719
NZ_CP015834_2	2.5\|3073898\|32\|NZ_CP015834\|CRT,CRISPRCasFinder,PILER-CR	3073898-3073929	32	MK599315	Pseudomonas phage PA1C, complete genome	257887-257918	9	0.719
NZ_CP015834_2	2.6\|3073959\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3073959-3073990	32	MN812211	Flavobacterium phage vB_FspS_laban6-1, complete genome	21752-21783	9	0.719
NZ_CP015834_2	2.6\|3073959\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3073959-3073990	32	NZ_CP012534	Psychrobacter sp. P11G5 plasmid pPspP11G5a, complete sequence	26937-26968	9	0.719
NZ_CP015834_2	2.8\|3074081\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074081-3074112	32	MT446414	UNVERIFIED: Escherichia virus TH43, complete genome	38100-38131	9	0.719
NZ_CP015834_2	2.10\|3074203\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074203-3074234	32	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	137043-137074	9	0.719
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	555186-555217	9	0.719
NZ_CP015834_2	2.12\|3074325\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3074325-3074356	32	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	471692-471723	9	0.719
NZ_CP015834_2	2.15\|3073959\|33\|NZ_CP015834\|PILER-CR	3073959-3073991	33	MN812211	Flavobacterium phage vB_FspS_laban6-1, complete genome	21752-21784	9	0.727
NZ_CP015834_2	2.17\|3074082\|32\|NZ_CP015834\|PILER-CR	3074082-3074113	32	MT446414	UNVERIFIED: Escherichia virus TH43, complete genome	38100-38131	9	0.719
NZ_CP015834_2	2.19\|3074204\|32\|NZ_CP015834\|PILER-CR	3074204-3074235	32	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	137043-137074	9	0.719
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	555186-555217	9	0.719
NZ_CP015834_2	2.21\|3074326\|32\|NZ_CP015834\|PILER-CR	3074326-3074357	32	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	471692-471723	9	0.719
NZ_CP015834_3	3.2\|3100145\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100145-3100176	32	MK448690	Streptococcus phage Javan169, complete genome	9831-9862	9	0.719
NZ_CP015834_3	3.2\|3100145\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100145-3100176	32	MK448854	Streptococcus phage Javan146, complete genome	11811-11842	9	0.719
NZ_CP015834_3	3.6\|3100389\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100389-3100420	32	NZ_CP016721	Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11B, complete sequence	30466-30497	9	0.719
NZ_CP015834_3	3.6\|3100389\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100389-3100420	32	NZ_CP016727	Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08B, complete sequence	30464-30495	9	0.719
NZ_CP015834_3	3.12\|3100757\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100757-3100788	32	MW084976	Bacillus phage Kirov, complete genome	56770-56801	9	0.719
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	JX469828	Uncultured bacterium plasmid pRSB223, complete sequence	47585-47616	9	0.719
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	JX469829	Uncultured bacterium plasmid pB1, complete sequence	23183-23214	9	0.719
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	393203-393234	9	0.719
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NC_008766	Acidovorax sp. JS42 plasmid pAOVO02, complete sequence	3158-3189	9	0.719
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	569059-569090	9	0.719
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NZ_MN366361	Bacterium plasmid pALTS33, complete sequence	54575-54606	9	0.719
NZ_CP015834_3	3.25\|3100267\|33\|NZ_CP015834\|PILER-CR	3100267-3100299	33	MN855615	Siphoviridae sp. isolate 320, complete genome	7075-7107	9	0.727
NZ_CP015834_3	3.30\|3100572\|34\|NZ_CP015834\|PILER-CR	3100572-3100605	34	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	413540-413573	9	0.735
NZ_CP015834_2	2.6\|3073959\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3073959-3073990	32	NZ_KX711616	Bacillus subtilis strain 72 plasmid pBS72, complete sequence	1474-1505	10	0.688
NZ_CP015834_3	3.14\|3100879\|32\|NZ_CP015834\|CRISPRCasFinder,CRT	3100879-3100910	32	NC_004929	Ruegeria sp. PR1b plasmid pSD20, complete sequence	67373-67404	10	0.688
NZ_CP015834_2	2.6\|3073959\|32\|NZ_CP015834\|CRT,CRISPRCasFinder	3073959-3073990	32	NC_023026	Francisella novicida strain PA10-7858 plasmid pFNPA10, complete sequence	2981-3012	11	0.656
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15004-15060	11	0.807
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	12104-12160	13	0.772
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	263-319	14	0.754
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	31243-31299	15	0.737
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3364-3420	16	0.719
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3363-3419	16	0.719
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3363-3419	16	0.719
NZ_CP015834_4	4.1\|4973786\|57\|NZ_CP015834\|CRISPRCasFinder	4973786-4973842	57	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3363-3419	16	0.719

1. spacer 2.1|3073653|32|NZ_CP015834|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 3, identity: 0.906

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
caagtgatgtccatcatcgcatccagtgcgtc	Protospacer
.*******.*********************.*

2. spacer 2.5|3073898|32|NZ_CP015834|CRT,CRISPRCasFinder,PILER-CR matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 4, identity: 0.875

-tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
ttttataag-gaggtgaatttatggaaacagta	Protospacer
 * *****. ******************* ***

3. spacer 2.5|3073898|32|NZ_CP015834|CRT,CRISPRCasFinder,PILER-CR matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 4, identity: 0.875

-tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
ttttataag-gaggtgaatttatggaaacagta	Protospacer
 * *****. ******************* ***

4. spacer 2.5|3073898|32|NZ_CP015834|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

-tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
ttttatagg-gaggtgaatttatggaaacagta	Protospacer
 * ****.. ******************* ***

5. spacer 2.13|3074386|32|NZ_CP015834|CRT,CRISPRCasFinder matches to MK972713 (Salmonella phage SW5, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

6. spacer 2.13|3074386|32|NZ_CP015834|CRT,CRISPRCasFinder matches to MK972714 (Salmonella phage SW3, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

7. spacer 2.13|3074386|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NC_049460 (Salmonella phage SI7, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

8. spacer 2.22|3074387|32|NZ_CP015834|PILER-CR matches to MK972713 (Salmonella phage SW5, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

9. spacer 2.22|3074387|32|NZ_CP015834|PILER-CR matches to MK972714 (Salmonella phage SW3, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

10. spacer 2.22|3074387|32|NZ_CP015834|PILER-CR matches to NC_049460 (Salmonella phage SI7, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

11. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 6, identity: 0.812

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cggcgttcgacgaactgcgcgatggccgcgtg	Protospacer
**.*********** *********** *.  *

12. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 6, identity: 0.812

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
caacgatggacgaaatgcgcgatggcgaacgc	Protospacer
*.*** * *******************. **

13. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 6, identity: 0.812

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cggcgttcgacgaactgcgcgatggccgcgtg	Protospacer
**.*********** *********** *.  *

14. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 6, identity: 0.812

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
caacgatggacgaaatgcgcgatggcgaacgc	Protospacer
*.*** * *******************. **

15. spacer 2.1|3073653|32|NZ_CP015834|CRT matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 7, identity: 0.781

taagtgat-atccatcatcgcatccagtgcgcc	CRISPR spacer
-ggttgatcgtccttcatcgcagccagtgcgcc	Protospacer
 .. **** .*** ******** **********

16. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.781

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cagcgatggacgaaatgcgcgatggcgaacgc	Protospacer
*..** * *******************. **

17. spacer 2.14|3074447|32|NZ_CP015834|CRT,CRISPRCasFinder matches to LR597649 (Escherichia phage ESSI2_ev015 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

18. spacer 2.14|3074447|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NC_049393 (Escherichia phage ESSI2_ev040 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

19. spacer 2.14|3074447|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NC_049394 (Escherichia phage ESSI2_ev129 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

20. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.781

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cagcgatggacgaaatgcgcgatggcgaacgc	Protospacer
*..** * *******************. **

21. spacer 2.23|3074448|32|NZ_CP015834|PILER-CR matches to LR597649 (Escherichia phage ESSI2_ev015 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

22. spacer 2.23|3074448|32|NZ_CP015834|PILER-CR matches to NC_049393 (Escherichia phage ESSI2_ev040 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

23. spacer 2.23|3074448|32|NZ_CP015834|PILER-CR matches to NC_049394 (Escherichia phage ESSI2_ev129 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

24. spacer 3.18|3101123|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NC_018022 (Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence) position: , mismatch: 7, identity: 0.781

-ccaggtcccatttgtcgatcggcagcgccatt	CRISPR spacer
agcatgt-gcatttgtccatcggcatcgccatc	Protospacer
  ** **  ******** ******* ******.

25. spacer 2.1|3073653|32|NZ_CP015834|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

taagtg---atatccatcatcgcatccagtgcgcc	CRISPR spacer
---gtgcgcccctccatcaccgcttccagtgcgcc	Protospacer
   ***    . *******.*** ***********

26. spacer 2.7|3074020|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP008818 (Ochrobactrum anthropi strain OAB plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.75

aatattgtcgtggacaaatgccggtgttattg-	CRISPR spacer
aattgtgtcgtggacaaatgcc-gcgtcgccga	Protospacer
***  ***************** *.**....*

27. spacer 2.7|3074020|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NC_009671 (Ochrobactrum anthropi ATCC 49188 plasmid pOANT03, complete sequence) position: , mismatch: 8, identity: 0.75

aatattgtcgtggacaaatgccggtgttattg-	CRISPR spacer
aattgtgtcgtggacaaatgcc-gcgtcgccga	Protospacer
***  ***************** *.**....*

28. spacer 2.9|3074142|32|NZ_CP015834|CRT,CRISPRCasFinder matches to MN694482 (Marine virus AFVG_250M11, complete genome) position: , mismatch: 8, identity: 0.75

caggtatcaagaaataatcgaagccttcatga	CRISPR spacer
aactaaactagaaaaaatcgaagccttaatga	Protospacer
 *   * * ***** ************ ****

29. spacer 2.10|3074203|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP024236 (Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

aattgattgctgggtgatattggaaaatgttg-	CRISPR spacer
cccggagtgctgggtgatattagaaaa-gttac	Protospacer
  . ** **************.***** ***.

30. spacer 2.11|3074264|32|NZ_CP015834|CRT,CRISPRCasFinder matches to CP022610 (Escherichia coli strain ATCC 700415 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

taccgtacagactgccggatattatttttttg	CRISPR spacer
ctcgctaaagactgccggatatgatttttctt	Protospacer
. *  ** ************** ******.*

31. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NC_031109 (Gordonia phage Jumbo, complete genome) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cgacgttcgacaaaatccgcgatggtattgtc	Protospacer
***********.**** ********.. *

32. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP050093 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcgttcgccgaaatgcgcgatgccgtcaga	Protospacer
 *.****** ************** ** . *.

33. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NC_008384 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcgttcgccgaaatgcgcgatgccgtcaga	Protospacer
 *.****** ************** ** . *.

34. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP042332 (Bosea sp. F3-2 plasmid pB32-1, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcggtcgacgaaatgcgcgacggcgtcgtg	Protospacer
 *.** ****************.**** .  *

35. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
ccatattcgccgaattgcgcgatggcggcggc	Protospacer
* *..**** **** *************. *

36. spacer 2.16|3074021|32|NZ_CP015834|PILER-CR matches to NZ_CP008818 (Ochrobactrum anthropi strain OAB plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.75

aatattgtcgtggacaaatgccggtgttattg-	CRISPR spacer
aattgtgtcgtggacaaatgcc-gcgtcgccga	Protospacer
***  ***************** *.**....*

37. spacer 2.16|3074021|32|NZ_CP015834|PILER-CR matches to NC_009671 (Ochrobactrum anthropi ATCC 49188 plasmid pOANT03, complete sequence) position: , mismatch: 8, identity: 0.75

aatattgtcgtggacaaatgccggtgttattg-	CRISPR spacer
aattgtgtcgtggacaaatgcc-gcgtcgccga	Protospacer
***  ***************** *.**....*

38. spacer 2.18|3074143|32|NZ_CP015834|PILER-CR matches to MN694482 (Marine virus AFVG_250M11, complete genome) position: , mismatch: 8, identity: 0.75

caggtatcaagaaataatcgaagccttcatga	CRISPR spacer
aactaaactagaaaaaatcgaagccttaatga	Protospacer
 *   * * ***** ************ ****

39. spacer 2.19|3074204|32|NZ_CP015834|PILER-CR matches to NZ_CP024236 (Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

aattgattgctgggtgatattggaaaatgttg-	CRISPR spacer
cccggagtgctgggtgatattagaaaa-gttac	Protospacer
  . ** **************.***** ***.

40. spacer 2.20|3074265|32|NZ_CP015834|PILER-CR matches to CP022610 (Escherichia coli strain ATCC 700415 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

taccgtacagactgccggatattatttttttg	CRISPR spacer
ctcgctaaagactgccggatatgatttttctt	Protospacer
. *  ** ************** ******.*

41. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NC_031109 (Gordonia phage Jumbo, complete genome) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cgacgttcgacaaaatccgcgatggtattgtc	Protospacer
***********.**** ********.. *

42. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NZ_CP050093 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcgttcgccgaaatgcgcgatgccgtcaga	Protospacer
 *.****** ************** ** . *.

43. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NC_008384 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcgttcgccgaaatgcgcgatgccgtcaga	Protospacer
 *.****** ************** ** . *.

44. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NZ_CP042332 (Bosea sp. F3-2 plasmid pB32-1, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcggtcgacgaaatgcgcgacggcgtcgtg	Protospacer
 *.** ****************.**** .  *

45. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
ccatattcgccgaattgcgcgatggcggcggc	Protospacer
* *..**** **** *************. *

46. spacer 3.4|3100267|32|NZ_CP015834|CRISPRCasFinder,CRT matches to MN855615 (Siphoviridae sp. isolate 320, complete genome) position: , mismatch: 8, identity: 0.75

tatgcgcttgctgctgcgttgatgtacgcggc	CRISPR spacer
tatgcgcttgctggtgctttgatgggcagtgg	Protospacer
************* *** ****** .*.  *

47. spacer 3.4|3100267|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NC_034248 (Rhizobium phage RHEph10, complete genome) position: , mismatch: 8, identity: 0.75

tatgcgcttgctgctgcgttgatgtacgcggc	CRISPR spacer
tctccttatgctgctgcgttgatggccgcggt	Protospacer
* * * . ****************  *****.

48. spacer 3.9|3100572|33|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 8, identity: 0.758

gcgcggccgcgatatcgttagcactggctcccg	CRISPR spacer
cggcggccgcgatatcgttcgcgctgccgcgcc	Protospacer
  ***************** **.*** * * *

49. spacer 3.13|3100818|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NC_013085 (Synechococcus phage S-RSM4, complete genome) position: , mismatch: 8, identity: 0.75

aatttttccagtggtgtcgttgtaattaagga-----	CRISPR spacer
gatttttccaatgctgtcgttgt-----aggagctac	Protospacer
.*********.** *********     ****

50. spacer 3.13|3100818|32|NZ_CP015834|CRISPRCasFinder,CRT matches to FM207411 (Synechococcus phage S-RSM4 complete genome) position: , mismatch: 8, identity: 0.75

aatttttccagtggtgtcgttgtaattaagga-----	CRISPR spacer
gatttttccaatgctgtcgttgt-----aggagctac	Protospacer
.*********.** *********     ****

51. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ggacgaagcaggcgcgcggggcgctggcgggg	Protospacer
.*.. **. ******** ********** ***

52. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP053710 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ggacgaagcaggcgcgcggggcgctggcgggg	Protospacer
.*.. **. ******** ********** ***

53. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP053712 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.75

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ggacgaagcaggcgcgcggggcgctggcgggg	Protospacer
.*.. **. ******** ********** ***

54. spacer 1.2|1016159|32|NZ_CP015834|CRISPRCasFinder matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttcactggtaacatactccacccgcccaccat	CRISPR spacer
tgtcctggtaacatgttccacccgcccggtgt	Protospacer
* . **********..***********. ..*

55. spacer 1.2|1016159|32|NZ_CP015834|CRISPRCasFinder matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttcactggtaacatactccacccgcccaccat	CRISPR spacer
tgtcctggtaacatgttccacccgcccggtgt	Protospacer
* . **********..***********. ..*

56. spacer 1.2|1016159|32|NZ_CP015834|CRISPRCasFinder matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttcactggtaacatactccacccgcccaccat	CRISPR spacer
tgtcctggtaacatgttccacccgcccggtgt	Protospacer
* . **********..***********. ..*

57. spacer 2.1|3073653|32|NZ_CP015834|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.719

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
ctcatcgcatccatcatcggttccagtgcgcc	Protospacer
.  .* ..***********  ***********

58. spacer 2.5|3073898|32|NZ_CP015834|CRT,CRISPRCasFinder,PILER-CR matches to MN693584 (Marine virus AFVG_25M163, complete genome) position: , mismatch: 9, identity: 0.719

tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
aatataaacgaggtgagtttatagatatcccc	Protospacer
 ***************.*****.** *.. .

59. spacer 2.5|3073898|32|NZ_CP015834|CRT,CRISPRCasFinder,PILER-CR matches to MN103543 (Pseudomonas phage vB_PaeM_PS119XW, complete genome) position: , mismatch: 9, identity: 0.719

tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
tccataaccgaggtgaatgtatggaagaagcg	Protospacer
* .**** ********** *******.  *..

60. spacer 2.5|3073898|32|NZ_CP015834|CRT,CRISPRCasFinder,PILER-CR matches to MK599315 (Pseudomonas phage PA1C, complete genome) position: , mismatch: 9, identity: 0.719

tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
tccataaccgaggtgaatgtatggaagaagcg	Protospacer
* .**** ********** *******.  *..

61. spacer 2.6|3073959|32|NZ_CP015834|CRT,CRISPRCasFinder matches to MN812211 (Flavobacterium phage vB_FspS_laban6-1, complete genome) position: , mismatch: 9, identity: 0.719

gttagttttctgaaaaaattgttttcttacgc	CRISPR spacer
atcttttttaagaaaaaattgttttcttattt	Protospacer
.*.  ****  ******************. .

62. spacer 2.6|3073959|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP012534 (Psychrobacter sp. P11G5 plasmid pPspP11G5a, complete sequence) position: , mismatch: 9, identity: 0.719

gttagttt---tctgaaaaaattgttttcttacgc	CRISPR spacer
---catctggaactggaaaaactgttttcttacgc	Protospacer
    .*.*    ***.*****.*************

63. spacer 2.8|3074081|32|NZ_CP015834|CRT,CRISPRCasFinder matches to MT446414 (UNVERIFIED: Escherichia virus TH43, complete genome) position: , mismatch: 9, identity: 0.719

ttcgagacacttctctgcaaaattaatgaaat	CRISPR spacer
ataaatttccttctctgcaaagttgatgaaat	Protospacer
 * .*  . ************.**.*******

64. spacer 2.10|3074203|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

aattgattgctgggtgatattggaaaatgttg	CRISPR spacer
atttgatagctggctgatattggaaggcaatc	Protospacer
* ***** ***** ***********.... *

65. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
ctctcagcgacgaactgcgcgatgccggtcga	Protospacer
*  .   ******* ********* ******.

66. spacer 2.12|3074325|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
atgtgctcgaggaaatgcgcgatgccggtctc	Protospacer
  ..*.**** ************* *****

67. spacer 2.15|3073959|33|NZ_CP015834|PILER-CR matches to MN812211 (Flavobacterium phage vB_FspS_laban6-1, complete genome) position: , mismatch: 9, identity: 0.727

gttagttttctgaaaaaattgttttcttacgct	CRISPR spacer
atcttttttaagaaaaaattgttttcttatttt	Protospacer
.*.  ****  ******************. .*

68. spacer 2.17|3074082|32|NZ_CP015834|PILER-CR matches to MT446414 (UNVERIFIED: Escherichia virus TH43, complete genome) position: , mismatch: 9, identity: 0.719

ttcgagacacttctctgcaaaattaatgaaat	CRISPR spacer
ataaatttccttctctgcaaagttgatgaaat	Protospacer
 * .*  . ************.**.*******

69. spacer 2.19|3074204|32|NZ_CP015834|PILER-CR matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

aattgattgctgggtgatattggaaaatgttg	CRISPR spacer
atttgatagctggctgatattggaaggcaatc	Protospacer
* ***** ***** ***********.... *

70. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
ctctcagcgacgaactgcgcgatgccggtcga	Protospacer
*  .   ******* ********* ******.

71. spacer 2.21|3074326|32|NZ_CP015834|PILER-CR matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
atgtgctcgaggaaatgcgcgatgccggtctc	Protospacer
  ..*.**** ************* *****

72. spacer 3.2|3100145|32|NZ_CP015834|CRISPRCasFinder,CRT matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 9, identity: 0.719

aatatccgttcctcgctctgcgttttcgttga	CRISPR spacer
gaaatccgtttctcgctctccgttttgctctt	Protospacer
.* *******.******** ******  *.

73. spacer 3.2|3100145|32|NZ_CP015834|CRISPRCasFinder,CRT matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 9, identity: 0.719

aatatccgttcctcgctctgcgttttcgttga	CRISPR spacer
gaaatccgtttctcgctctccgttttgctctt	Protospacer
.* *******.******** ******  *.

74. spacer 3.6|3100389|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP016721 (Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11B, complete sequence) position: , mismatch: 9, identity: 0.719

gattcaatgtccgacgcatccaagtaaatatt	CRISPR spacer
ctttcaatgtcctacgcattcaagtcatgaaa	Protospacer
  ********** ******.***** *  *

75. spacer 3.6|3100389|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP016727 (Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08B, complete sequence) position: , mismatch: 9, identity: 0.719

gattcaatgtccgacgcatccaagtaaatatt	CRISPR spacer
ctttcaatgtcctacgcattcaagtcatgaaa	Protospacer
  ********** ******.***** *  *

76. spacer 3.12|3100757|32|NZ_CP015834|CRISPRCasFinder,CRT matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 9, identity: 0.719

tgactgaccgggaaaagaaaacacctggcgaa	CRISPR spacer
ttatagactgggaaaagaaaacacttggaatt	Protospacer
* *. ***.***************.*** .

77. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to JX469828 (Uncultured bacterium plasmid pRSB223, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

78. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to JX469829 (Uncultured bacterium plasmid pB1, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

79. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
tgatggctgaggcgcgccgggcgctgcccggc	Protospacer
 *.* .  ****************** *.**

80. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NC_008766 (Acidovorax sp. JS42 plasmid pAOVO02, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

81. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
catgtgaagcggcgcgccgggcgcgggctccg	Protospacer
 .  *.*** ************** ****  *

82. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NZ_MN366361 (Bacterium plasmid pALTS33, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

83. spacer 3.25|3100267|33|NZ_CP015834|PILER-CR matches to MN855615 (Siphoviridae sp. isolate 320, complete genome) position: , mismatch: 9, identity: 0.727

tatgcgcttgctgctgcgttgatgtacgcggcc	CRISPR spacer
tatgcgcttgctggtgctttgatgggcagtggt	Protospacer
************* *** ****** .*.  * .

84. spacer 3.30|3100572|34|NZ_CP015834|PILER-CR matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 9, identity: 0.735

gcgcggccgcgatatcgttagcactggctcccgc	CRISPR spacer
cggcggccgcgatatcgttcgcgctgccgcgccg	Protospacer
  ***************** **.*** * * *

85. spacer 2.6|3073959|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NZ_KX711616 (Bacillus subtilis strain 72 plasmid pBS72, complete sequence) position: , mismatch: 10, identity: 0.688

gttagttttctgaaaaaattgttttcttacgc	CRISPR spacer
aaagcttttcttaaaagattgttttctttgtc	Protospacer
.  . ****** ****.***********   *

86. spacer 3.14|3100879|32|NZ_CP015834|CRISPRCasFinder,CRT matches to NC_004929 (Ruegeria sp. PR1b plasmid pSD20, complete sequence) position: , mismatch: 10, identity: 0.688

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccctctggcaggcgcgccgggcgcaggcgggg	Protospacer
   *. .. *************** *** ***

87. spacer 2.6|3073959|32|NZ_CP015834|CRT,CRISPRCasFinder matches to NC_023026 (Francisella novicida strain PA10-7858 plasmid pFNPA10, complete sequence) position: , mismatch: 11, identity: 0.656

gttagttttctgaaaaaattgttttcttacgc	CRISPR spacer
aacgccactctgaaaaagttgttttctttcgt	Protospacer
. .. . .*********.********** **.

88. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 11, identity: 0.807

-acaataacagcattgcctgatgcgacgctgccgcgtcttatcaggcctacgagttca	CRISPR spacer
aacaattacca-ggtgcctgatgcgacgctggcgcgtcttatcatgcctacgagcccg	Protospacer
 ***** ** . . ***************** ************ *********..*.

89. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 13, identity: 0.772

-----acaataacagcattgcctgatgcgacgctgccgcgtcttatcaggcctacgagtt	CRISPR spacer
ctccgacgtt-----cggtgcctgatgcgacgctggcgcgtcttatcaggcctacgagtc	Protospacer
     **. *     *. ***************** ***********************.

90. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 14, identity: 0.754

-----acaataacagcattgcctgatgcgacgctgccgcgtcttatcaggcctacgagtt	CRISPR spacer
atccggcaat-----caatgcctgatgcgacgctgtcgcgtcttatcaggcctacaaacc	Protospacer
     .****     ** *****************.*******************.*...

91. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 15, identity: 0.737

--acaataacagcattgcctgatgcgacgctgccgcgtcttatcaggcctacgagttca	CRISPR spacer
atccggtaat--caatgcctgatgcgacgctgtcgcgtcttatcaggcctacagccgtt	Protospacer
   *..***.  ** *****************.*******************.. . .

92. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 16, identity: 0.719

acaataacagcat-----tgcctgatgcgacgctgccgcgtcttatcaggcctacgagtt	CRISPR spacer
-----agttgtacgcaggtgcctgatgcgacgctggcgcgtcttatcatgcctacgagcc	Protospacer
     *.. *.*.     ***************** ************ *********..

93. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 16, identity: 0.719

acaataacagcat-----tgcctgatgcgacgctgccgcgtcttatcaggcctacgagtt	CRISPR spacer
-----agttgtacgcaggtgcctgatgcgacgctggcgcgtcttatcatgcctacgagcc	Protospacer
     *.. *.*.     ***************** ************ *********..

94. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 16, identity: 0.719

acaataacagcat-----tgcctgatgcgacgctgccgcgtcttatcaggcctacgagtt	CRISPR spacer
-----agttgtacgcaggtgcctgatgcgacgctggcgcgtcttatcatgcctacgagcc	Protospacer
     *.. *.*.     ***************** ************ *********..

95. spacer 4.1|4973786|57|NZ_CP015834|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 16, identity: 0.719

acaataacagcat-----tgcctgatgcgacgctgccgcgtcttatcaggcctacgagtt	CRISPR spacer
-----agttgtacgcaggtgcctgatgcgacgctggcgcgtcttatcatgcctacgagcc	Protospacer
     *.. *.*.     ***************** ************ *********..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

204459 : 270284

Emiliania_huxleyi_virus(11.11%)

plate,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022645195.1\|204459_205812_+\|protease	sigma E protease regulator RseP	NA	NA	NA	NA
WP_001240896.1\|205841_208274_+	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_000758956.1\|208395_208881_+	molecular chaperone Skp	NA	NA	NA	NA
WP_001139282.1\|208884_209910_+	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_000210739.1\|210014_210470_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_000565966.1\|210473_211262_+	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_022645196.1\|211261_212410_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_022645197.1\|212406_213003_+	ribonuclease HII	V5LS49	Emiliania_huxleyi_virus	2.3e-26	40.0
WP_001294757.1\|213039_216522_+	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	2.2e-209	36.9
WP_000055746.1\|216534_217494_+	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_001020966.1\|217592_219734_+	lysine decarboxylase LdcC	NA	NA	NA	NA
WP_000901098.1\|219790_220180_+	VOC family protein	NA	NA	NA	NA
WP_022645198.1\|220244_221543_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_000062318.1\|221591_221852_-	Rho-binding antiterminator	NA	NA	NA	NA
WP_000417058.1\|221838_222039_-	YaeP family protein	NA	NA	NA	NA
WP_001185283.1\|222204_222750_+	YaeQ family protein	NA	NA	NA	NA
WP_000635528.1\|222746_223169_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000239184.1\|223182_223893_+	envelope stress response activation lipoprotein NlpE	NA	NA	NA	NA
WP_022645199.1\|224048_224873_-	YaeF family permuted papain-like enzyme	NA	NA	NA	NA
WP_022645200.1\|224925_226644_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_000094006.1\|226754_227462_-\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_001202329.1\|227458_227863_-	Rcs stress response system protein RcsF	NA	NA	NA	NA
WP_069383053.1\|227980_228796_-	methionine ABC transporter substrate-binding lipoprotein MetQ	NA	NA	NA	NA
WP_001294600.1\|228835_229489_-	methionine ABC transporter permease MetI	NA	NA	NA	NA
WP_000593991.1\|229481_230513_-	methionine ABC transporter ATP-binding protein MetN	G9BWD6	Planktothrix_phage	7.2e-36	40.2
WP_001140178.1\|230700_231273_+	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase	NA	NA	NA	NA
WP_022645201.1\|237042_237846_+	2,5-didehydrogluconate reductase DkgB	A0A1V0SDE7	Indivirus	2.7e-38	35.8
WP_000648568.1\|237842_238757_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001230983.1\|238997_239798_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000211702.1\|239874_240645_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000644685.1\|240692_242051_-	murein transglycosylase D	A0A2H4J9N7	uncultured_Caudovirales_phage	5.8e-09	36.0
WP_001052732.1\|242122_242878_-	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_001308373.1\|242911_243634_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000917883.1\|243630_244098_-	ribonuclease HI	J9Q745	Salmonella_phage	1.0e-50	58.7
WP_001308374.1\|244162_244894_+	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	7.6e-40	38.6
WP_022645202.1\|245428_246214_+	hypothetical protein	NA	NA	NA	NA
WP_022645203.1\|246363_246831_-	hypothetical protein	NA	NA	NA	NA
WP_022645204.1\|246845_247754_-	hypothetical protein	NA	NA	NA	NA
WP_022645205.1\|247797_248280_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_022645206.1\|248303_249656_-	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_122988716.1\|249666_253101_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_022645208.1\|253209_254625_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_022645209.1\|254629_255373_-	type VI secretion system-associated protein TagO	NA	NA	NA	NA
WP_022645210.1\|255369_258129_-	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	7.2e-83	29.0
WP_022645211.1\|258137_258899_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_022645212.1\|258903_260235_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_001080149.1\|260237_260762_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_001113710.1\|260758_262039_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_022645213.1\|262063_263146_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_022645214.1\|263109_264960_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_022645215.1\|264963_265377_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_022645216.1\|265383_266859_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_022645217.1\|266909_267134_-	hypothetical protein	NA	NA	NA	NA
WP_000037391.1\|267168_267669_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_001142958.1\|268365_268884_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_085949836.1\|269070_270284_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	4.7e-103	58.4

DBSCAN-SWA_2

548486 : 614801

Enterobacteria_phage(61.11%)

tRNA,head,terminase,capsid,portal,lysis,integrase,tail,protease,transposase

attL 558638:558684|attR 606347:606393

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000912345.1\|548486_549872_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.9e-45	34.8
WP_001143564.1\|549907_550429_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_000190288.1\|550536_550749_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_000729155.1\|550750_551617_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
WP_000776555.1\|552088_552631_+	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
WP_022645303.1\|552850_553543_+	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_022645304.1\|553573_556183_+	fimbrial biogenesis usher protein	NA	NA	NA	NA
WP_000691076.1\|556195_557203_+	type 1 fimbrin D-mannose specific adhesin FimH	NA	NA	NA	NA
WP_001255235.1\|557213_557729_+	fimbria assembly protein	NA	NA	NA	NA
WP_000805428.1\|557731_558364_-	fimbria biosynthesis transcriptional regulator FimZ	NA	NA	NA	NA
558638:558684	attL	NA	NA	NA	NA
WP_001299447.1\|558697_559861_-\|integrase	site-specific integrase	A0A088CD23	Shigella_phage	3.4e-199	86.3
WP_000488407.1\|560059_560338_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
WP_022645305.1\|560385_560604_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	5.4e-34	97.2
WP_000548537.1\|560995_561187_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_000149544.1\|561159_561342_-	DUF1317 domain-containing protein	A0A1U8QQC1	Enterobacteria_phage	6.9e-27	96.7
WP_000186848.1\|561338_562019_-	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	1.6e-132	100.0
WP_022645306.1\|562015_562801_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.9e-148	99.2
WP_020241285.1\|562806_563103_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	3.6e-49	99.0
WP_000233579.1\|563179_563386_-	hypothetical protein	K7PM31	Enterobacteria_phage	7.1e-28	83.8
WP_000858975.1\|563980_564670_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.8e-92	75.0
WP_001067458.1\|564774_565005_+	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
WP_001182772.1\|565074_565614_+	toxin YdaT domain-containing protein	M9NZI6	Enterobacteria_phage	1.5e-61	66.1
WP_000147901.1\|565610_566630_+	replication protein	A0A0M5M7Y1	Salmonella_phage	4.4e-110	63.8
WP_000788890.1\|566626_567328_+	Replication protein P	M1FJ72	Enterobacteria_phage	7.9e-127	97.4
WP_000145902.1\|567324_567627_+	hypothetical protein	A0A0N6WES4	Escherichia_phage	1.7e-41	93.5
WP_001070451.1\|567694_568027_+	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_032139864.1\|568118_568226_+	hypothetical protein	NA	NA	NA	NA
WP_000709074.1\|568283_569810_+	recombinase family protein	Q3HQV4	Burkholderia_phage	3.6e-31	27.7
WP_001351655.1\|569921_570245_+	hypothetical protein	NA	NA	NA	NA
WP_000379700.1\|570706_571063_+	hypothetical protein	NA	NA	NA	NA
WP_072130332.1\|571152_571254_+	hypothetical protein	NA	NA	NA	NA
WP_001053034.1\|571250_571706_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	4.9e-61	67.5
WP_000224912.1\|571705_571876_+	hypothetical protein	K7P7K0	Enterobacteria_phage	1.4e-13	69.8
WP_000774504.1\|571868_572159_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.8e-46	92.7
WP_001099712.1\|572155_572518_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	4.3e-60	96.5
WP_000971074.1\|572514_572655_+	YlcG family protein	K7PHH3	Enterobacteria_phage	6.5e-09	69.8
WP_022645308.1\|572740_573118_+	antitermination protein Q	Q777W5	Enterobacteria_phage	8.1e-54	83.3
WP_000780581.1\|573273_573798_-	lipocalin family protein	A0A1W6JNX6	Morganella_phage	1.1e-48	54.1
WP_000592546.1\|573990_574950_+	DUF523 and DUF1722 domain-containing protein	NA	NA	NA	NA
WP_022645309.1\|575301_576033_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000839582.1\|576997_577213_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	1.2e-33	98.6
WP_001135261.1\|577212_577710_+	lysozyme RrrD	A0A1B5FP97	Escherichia_phage	4.2e-90	97.6
WP_000092273.1\|577706_578174_+\|lysis	lysis protein	A0A2D1GLQ7	Escherichia_phage	1.6e-75	96.8
WP_001139678.1\|578161_578314_+	hypothetical protein	K7PKL2	Enterobacteria_phage	3.1e-20	96.0
WP_000079508.1\|578665_579076_-	DUF1398 family protein	C6ZCX4	Enterobacteria_phage	1.3e-52	76.3
WP_000105084.1\|579132_579366_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.3e-21	94.4
WP_000453580.1\|579754_580300_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.8e-95	100.0
WP_001027268.1\|580274_582200_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.7
WP_000198149.1\|582196_582403_+	gpW family protein	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001553867.1\|582399_584001_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	8.5e-310	99.2
WP_022645310.1\|583981_585301_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	6.9e-233	98.2
WP_001297109.1\|585310_585643_+\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.2e-55	100.0
WP_022645311.1\|585698_586724_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.0e-191	99.4
WP_000158919.1\|586765_587164_+	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.1e-64	100.0
WP_000753007.1\|587175_587529_+\|head,tail	head-tail joining protein	A0A0K2FJB7	Enterobacteria_phage	4.4e-62	99.1
WP_001595432.1\|587540_588119_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
WP_000683105.1\|588115_588511_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_001547245.1\|588518_589259_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	1.7e-127	95.9
WP_001468358.1\|589274_589697_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.8e-71	97.9
WP_022645312.1\|589678_590113_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	1.5e-64	99.2
WP_069383054.1\|590105_592667_+\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	92.4
WP_000847321.1\|592663_592993_+\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	8.9e-57	97.2
WP_001152639.1\|592992_593691_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.3e-134	100.0
WP_022645314.1\|593696_594440_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	5.9e-149	97.6
WP_000090891.1\|594376_595009_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	2.2e-96	99.5
WP_023909233.1\|595069_598549_+	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	89.6
WP_038431964.1\|598616_599216_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	4.4e-102	92.5
WP_023909117.1\|599280_601638_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A1X7QGG5	Escherichia_phage	2.2e-117	50.1
WP_001204892.1\|601637_601907_+	hypothetical protein	NA	NA	NA	NA
WP_022645319.1\|601919_602960_+\|tail	tail fiber domain-containing protein	A0A0E3M4A9	Enterobacteria_phage	2.1e-176	91.9
WP_000386784.1\|603971_604721_+	DNA-binding transcriptional activator AppY	NA	NA	NA	NA
WP_001201842.1\|604969_605923_-\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001177457.1\|606435_607197_-	DNA-binding transcriptional regulator EnvY	NA	NA	NA	NA
606347:606393	attR	NA	NA	NA	NA
WP_022645321.1\|607379_608270_-	DUF4434 family protein	NA	NA	NA	NA
WP_022645322.1\|608270_611243_-	bacteriophage adsorption protein NfrA	NA	NA	NA	NA
WP_022645323.1\|611229_613467_-	phage adsorption protein NrfB	NA	NA	NA	NA
WP_022645324.1\|613664_614801_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

931981 : 1004759

Salmonella_phage(69.39%)

head,terminase,capsid,portal,lysis,plate,integrase,tail

attL 969999:970013|attR 1008487:1008501

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001595551.1\|931981_933034_-\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	4.8e-104	55.8
WP_022645415.1\|933116_934793_-	DUF4041 domain-containing protein	A0A142LP25	Marinitoga_camini_virus	9.8e-83	66.8
WP_022645416.1\|934813_935410_-	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.4e-39	42.9
WP_000188448.1\|935505_935727_+	hypothetical protein	NA	NA	NA	NA
WP_022645417.1\|935759_936269_+	phage regulatory CII family protein	E5G6L3	Salmonella_phage	1.3e-86	98.2
WP_000956182.1\|936276_936477_+	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	7.1e-33	98.5
WP_001311552.1\|936440_936782_+	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	1.7e-55	98.2
WP_001244228.1\|936849_937083_+	DUF2732 family protein	E5G6L6	Salmonella_phage	6.4e-33	98.7
WP_001399246.1\|937082_937310_+	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	7.8e-36	98.7
WP_000104157.1\|937306_938164_+	DNA adenine methylase	E5G6L8	Salmonella_phage	4.1e-162	98.2
WP_022645418.1\|938160_940575_+	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.6
WP_001154434.1\|940728_940917_+	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_001217562.1\|940927_941161_+	DinI family protein	E5G6M1	Salmonella_phage	2.3e-35	98.7
WP_022645419.1\|941335_942394_-	hypothetical protein	NA	NA	NA	NA
WP_022645420.1\|942927_944709_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_022645421.1\|944745_945780_-\|portal	phage portal protein	E5G6M3	Salmonella_phage	2.3e-167	85.5
WP_022645422.1\|945779_947546_-\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.5
WP_022645423.1\|947688_948522_+\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	2.8e-123	91.0
WP_000742503.1\|948538_949597_+\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	8.4e-181	93.1
WP_021534472.1\|949600_950251_+\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	9.6e-111	95.8
WP_000673523.1\|950346_950811_+\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	6.4e-77	89.6
WP_000868175.1\|950810_951014_+\|tail	tail protein X	E5G6M9	Salmonella_phage	1.4e-31	92.5
WP_000171568.1\|951017_951233_+	hypothetical protein	E5G6N0	Salmonella_phage	1.8e-26	80.3
WP_022645424.1\|951213_951726_+	lysozyme	E5G6N1	Salmonella_phage	2.0e-87	91.1
WP_022645425.1\|951727_952105_+	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	8.8e-16	40.0
WP_022645426.1\|952101_952530_+\|lysis	LysB family phage lysis regulatory protein	E5G6N2	Salmonella_phage	1.9e-46	75.2
WP_001595569.1\|952625_953057_+\|tail	phage tail protein	E5G6N3	Salmonella_phage	9.9e-72	93.7
WP_021522006.1\|953049_953496_+	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	4.0e-60	84.2
WP_022645427.1\|953437_954244_-	hypothetical protein	NA	NA	NA	NA
WP_000993764.1\|954347_954926_+\|plate	phage baseplate assembly protein V	A0A1S6KZX7	Salmonella_phage	7.2e-94	86.5
WP_000177597.1\|954922_955282_+	GPW/gp25 family protein	A0A1S6KZZ4	Salmonella_phage	2.8e-51	85.7
WP_022645428.1\|955268_956177_+\|plate	baseplate assembly protein	A0A1S6KZY6	Salmonella_phage	3.5e-143	90.7
WP_022645429.1\|956169_956775_+\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.2e-110	92.5
WP_022645430.1\|956771_958313_+\|tail	phage tail protein	M1TAS6	Escherichia_phage	7.6e-199	71.2
WP_022645431.1\|958312_958915_+\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	3.7e-93	84.4
WP_000046146.1\|959048_960221_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	7.8e-204	90.0
WP_001207660.1\|960230_960746_+\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	2.1e-89	95.3
WP_022645432.1\|960800_961103_+\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	3.5e-39	88.0
WP_000763311.1\|961117_961237_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.8e-13	87.2
WP_022645433.1\|961229_964307_+\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	69.3
WP_022645434.1\|964303_964789_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	1.6e-65	79.4
WP_022645435.1\|964785_965886_+	phage late control D family protein	E5G6Q3	Salmonella_phage	1.0e-176	85.2
WP_000972391.1\|965976_966195_+	ogr/Delta-like zinc finger family protein	Q53ZE7	Salmonella_virus	7.5e-20	69.0
WP_001024876.1\|966430_968116_-	aspartate:alanine antiporter	NA	NA	NA	NA
WP_000681108.1\|968385_968763_+	inner membrane protein YbjM	NA	NA	NA	NA
WP_001195231.1\|968792_969050_-	glutaredoxin 1	A0A2I7SAE2	Vibrio_phage	7.8e-24	63.1
WP_022645436.1\|969209_969497_+	DUF1418 family protein	NA	NA	NA	NA
WP_022645437.1\|969480_970203_+	nitroreductase NfsA	NA	NA	NA	NA
969999:970013	attL	NA	NA	NA	NA
WP_000684321.1\|970263_971166_+	30S ribosomal protein S6--L-glutamate ligase	I3ULC9	Synechococcus_phage	2.6e-37	34.4
WP_000203025.1\|971253_971730_+	YbjN domain-containing protein	NA	NA	NA	NA
WP_000126075.1\|972080_973193_+	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_000996007.1\|973287_974421_+	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	1.4e-29	34.0
WP_000105436.1\|974430_975384_+	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_001061658.1\|975380_976226_+	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_000389260.1\|976285_976774_+	YbjO family protein	NA	NA	NA	NA
WP_001149713.1\|976814_977942_+	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A1X9I6F4	Streptococcus_phage	3.5e-28	27.6
WP_001295905.1\|977970_978702_-	ABC transporter substrate-binding protein ArtJ	NA	NA	NA	NA
WP_000464489.1\|978927_979596_-	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_001001702.1\|979595_980312_-	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_000756575.1\|980318_981050_-	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000027205.1\|981067_981796_-	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	6.0e-29	36.7
WP_001270657.1\|982013_982529_-	lipoprotein	NA	NA	NA	NA
WP_022645438.1\|983176_984946_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_001160731.1\|985156_985480_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_001255167.1\|985476_986307_+	N-acetylmuramoyl-L-alanine amidase AmiD	A0A1B0UZW5	Roseobacter_phage	5.7e-07	30.0
WP_001305933.1\|986303_987317_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_022645439.1\|987415_988846_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000566375.1\|988856_989858_-	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_000815366.1\|989894_991613_-	ubiquinone-dependent pyruvate dehydrogenase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	6.8e-31	24.0
WP_000178691.1\|991745_992714_-	NADH oxidoreductase	NA	NA	NA	NA
WP_022645440.1\|992725_994378_-	hydroxylamine reductase	NA	NA	NA	NA
WP_022645441.1\|994520_995420_-	L-lysine exporter LysO	NA	NA	NA	NA
WP_000488716.1\|995877_996573_-	aquaporin Z	NA	NA	NA	NA
WP_000599806.1\|996998_998657_+	ATP-dependent endonuclease	NA	NA	NA	NA
WP_001400542.1\|998653_999610_-	DUF535 domain-containing protein	NA	NA	NA	NA
WP_000746460.1\|999760_1000876_+	macrolide transporter subunit MacA	NA	NA	NA	NA
WP_022645444.1\|1000872_1002819_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	6.5e-38	40.1
WP_000410785.1\|1002891_1003116_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	2.3e-16	61.2
WP_022645445.1\|1003520_1004759_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	4.5e-125	52.5
1008487:1008501	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1402149 : 1481739

Escherichia_phage(39.29%)

holin,head,terminase,capsid,portal,integrase,tail,protease,transposase

attL 1402937:1402953|attR 1429178:1429194

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024181814.1\|1402149_1403496_+\|transposase	IS4-like element IS4 family transposase	NA	NA	NA	NA
1402937:1402953	attL	NA	NA	NA	NA
WP_000301651.1\|1403550_1406226_-	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_022645592.1\|1406702_1407350_+	NAAT family transporter YchE	NA	NA	NA	NA
WP_001211525.1\|1407507_1407804_-	hypothetical protein	NA	NA	NA	NA
WP_000182039.1\|1408087_1409719_+	oligopeptide ABC transporter substrate-binding protein OppA	NA	NA	NA	NA
WP_000911112.1\|1409804_1410725_+	oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_000979659.1\|1410739_1411648_+	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_000110931.1\|1411659_1412673_+	murein tripeptide/oligopeptide ABC transporter ATP binding protein OppD	G9BWD6	Planktothrix_phage	2.0e-14	31.7
WP_000994905.1\|1412669_1413674_+	murein tripeptide/oligopeptide ABC transporter ATP binding protein OppF	G3M9Y6	Bacillus_virus	2.3e-15	30.7
WP_000366959.1\|1413726_1414056_-	YciU family protein	NA	NA	NA	NA
WP_000214516.1\|1414090_1415551_-	cardiolipin synthase	NA	NA	NA	NA
WP_001309467.1\|1415693_1415867_+	YciY family protein	NA	NA	NA	NA
WP_000020078.1\|1415921_1417175_-	voltage-gated potassium channel protein	NA	NA	NA	NA
WP_000967595.1\|1417475_1417772_-	YciI family protein	NA	NA	NA	NA
WP_001357407.1\|1417995_1418712_+	TonB system transport protein TonB	NA	NA	NA	NA
WP_000108160.1\|1418751_1419150_-	acyl-CoA thioester hydrolase YciA	NA	NA	NA	NA
WP_000808667.1\|1419254_1419794_-	septation protein A	NA	NA	NA	NA
WP_000028546.1\|1419823_1420567_-	UPF0259 family protein	NA	NA	NA	NA
WP_000737218.1\|1420923_1421577_+	outer membrane protein OmpW	NA	NA	NA	NA
WP_001735157.1\|1421622_1422753_-\|integrase	phage integrase Arm DNA-binding domain-containing protein	O21940	Phage_21	5.7e-103	51.4
WP_000113189.1\|1422730_1422979_-	excisionase	NA	NA	NA	NA
WP_022645593.1\|1423043_1425515_-	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.2
WP_001090200.1\|1425607_1425799_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449192.1\|1425795_1425984_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001171942.1\|1426551_1426770_-	hypothetical protein	NA	NA	NA	NA
WP_000379575.1\|1426929_1427085_-	DUF1391 family protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_000362153.1\|1427350_1427770_-	hypothetical protein	K7PK07	Enterobacteria_phage	8.8e-25	65.1
WP_000391950.1\|1427870_1428152_+	helix-turn-helix domain-containing protein	K7PHA1	Enterobacteria_phage	6.5e-24	72.6
WP_000693949.1\|1428135_1428561_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001262390.1\|1428632_1429703_+	hypothetical protein	A0A088CD36	Shigella_phage	2.6e-52	56.6
1429178:1429194	attR	NA	NA	NA	NA
WP_022645595.1\|1429743_1430166_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	7.4e-64	89.9
WP_000403785.1\|1430223_1430580_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.8e-58	99.2
WP_001224662.1\|1430673_1430856_+	hypothetical protein	A0A2R2Z308	Escherichia_phage	1.4e-27	100.0
WP_000753060.1\|1430848_1431025_+	hypothetical protein	A0A2R2X2A8	Escherichia_phage	6.7e-27	94.8
WP_000813254.1\|1431946_1432102_+	type I toxin-antitoxin system toxin HokD	A0A0U2QV81	Escherichia_phage	1.5e-17	96.1
WP_023141427.1\|1432269_1432542_+	hypothetical protein	I6PCV7	Cronobacter_phage	4.2e-12	50.8
WP_022645596.1\|1432543_1433602_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.4e-89	48.0
WP_000139998.1\|1433602_1433965_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	9.6e-36	63.6
WP_001545909.1\|1433979_1434801_+	antitermination protein	K7P7B9	Enterobacteria_phage	1.8e-77	58.6
WP_000562553.1\|1435697_1435829_+	DUF3927 family protein	H6WZJ7	Escherichia_phage	3.7e-06	100.0
WP_000871291.1\|1436109_1436445_-	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	5.2e-44	74.8
WP_000874243.1\|1436704_1436893_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	7.2e-27	95.2
WP_001323614.1\|1436889_1437051_+	hypothetical protein	Q08JA2	Stx2-converting_phage	5.4e-15	91.3
WP_000372595.1\|1437200_1437416_+\|holin	class II holin family protein	A0A2R2Z340	Escherichia_phage	3.4e-33	98.6
WP_000193264.1\|1437420_1437771_+	YdfR family protein	K7PGU6	Enterobacteria_phage	1.4e-36	94.0
WP_000992097.1\|1437834_1438368_+	lysozyme	Q08J98	Stx2-converting_phage	1.5e-98	93.2
WP_075202333.1\|1438584_1438767_+	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	2.2e-17	77.0
WP_000738421.1\|1438857_1439151_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	5.9e-44	90.7
WP_001415975.1\|1439510_1439705_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	4.3e-27	96.9
WP_000453611.1\|1440093_1440639_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.3e-94	98.3
WP_022645597.1\|1440613_1442539_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	98.9
WP_000198149.1\|1442535_1442742_+	gpW family protein	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_022645598.1\|1442738_1444340_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	8.5e-310	99.2
WP_022645599.1\|1444320_1445640_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	8.1e-234	98.6
WP_001338090.1\|1445649_1445982_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	6.5e-55	99.1
WP_032140162.1\|1446037_1447063_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	3.8e-186	96.8
WP_000158868.1\|1447104_1447500_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	5.7e-58	95.5
WP_000752960.1\|1447511_1447865_+\|head,tail	head-tail joining protein	A0A2R9YJJ5	Escherichia_phage	7.6e-62	99.1
WP_001398561.1\|1447876_1448455_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	8.6e-79	97.9
WP_021550753.1\|1448451_1448847_+\|tail	phage tail protein	A0A0K2FIF4	Enterobacteria_phage	8.5e-70	97.7
WP_001317730.1\|1448854_1449595_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	5.2e-129	97.2
WP_000479193.1\|1449610_1450033_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.2e-60	85.7
WP_000459457.1\|1450014_1450449_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_022645607.1\|1450441_1453003_+\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	89.3
WP_000847401.1\|1452999_1453329_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	6.0e-53	92.7
WP_001152612.1\|1453328_1454027_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.1e-132	98.7
WP_022645608.1\|1454031_1454775_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.9e-143	95.1
WP_071597161.1\|1454711_1455344_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	1.4e-95	99.0
WP_069383056.1\|1455404_1458884_+	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	89.5
WP_000290529.1\|1458942_1461288_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0E3M0V5	Enterobacteria_phage	9.5e-92	45.4
WP_000654156.1\|1461284_1461566_+	hypothetical protein	A0A1X7QHA1	Escherichia_phage	4.1e-18	50.0
WP_000235987.1\|1461575_1462280_+	hypothetical protein	A0A1X7QGH6	Escherichia_phage	9.2e-59	61.7
WP_000355602.1\|1462290_1462584_+	hypothetical protein	NA	NA	NA	NA
WP_022645610.1\|1462777_1463446_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000937495.1\|1463502_1463772_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	9.3e-20	79.4
WP_000251936.1\|1463886_1464057_+	hypothetical protein	A0A0U2RK60	Escherichia_phage	9.4e-10	62.5
WP_001056491.1\|1465096_1465597_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000807651.1\|1465682_1465862_-	general stress protein	NA	NA	NA	NA
WP_022645611.1\|1466252_1467059_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_022645612.1\|1467058_1468252_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_001195273.1\|1468263_1469622_-	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	3.9e-37	41.2
WP_000763524.1\|1469625_1471221_-	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	1.7e-52	38.5
WP_022645613.1\|1471220_1472783_-	anthranilate synthase component I	NA	NA	NA	NA
WP_001700591.1\|1472874_1472919_-	trp operon leader peptide	NA	NA	NA	NA
WP_001285663.1\|1473056_1473938_+	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001295575.1\|1473934_1474555_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_022645614.1\|1474582_1476472_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_001291217.1\|1476682_1477558_+	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_022645615.1\|1477727_1478750_+	hypothetical protein	NA	NA	NA	NA
WP_001000715.1\|1478759_1479068_+	hypothetical protein	NA	NA	NA	NA
WP_001278893.1\|1479124_1479715_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_000559277.1\|1479711_1480470_-	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	23.4
WP_000422059.1\|1480689_1481739_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5

DBSCAN-SWA_5

1699083 : 1766808

Enterobacteria_phage(50.0%)

terminase,lysis,portal,tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088895425.1\|1699083_1700312_-\|transposase	IS3-like element IS2 family transposase	Q9ZXG3	Shigella_phage	1.3e-177	99.3
WP_022645702.1\|1706807_1708400_-	autoinducer-2 kinase	NA	NA	NA	NA
WP_000154352.1\|1708478_1709432_-	transcriptional regulator LsrR	NA	NA	NA	NA
WP_001194902.1\|1709680_1711216_+	autoinducer 2 ABC transporter ATP-binding protein LsrA	A0A2H4PQG7	Staphylococcus_phage	3.2e-16	24.0
WP_022645703.1\|1711209_1712238_+	autoinducer 2 ABC transporter permease LsrC	NA	NA	NA	NA
WP_001222725.1\|1712237_1713230_+	autoinducer 2 ABC transporter permease LsrD	NA	NA	NA	NA
WP_000172485.1\|1713241_1714264_+	autoinducer 2 ABC transporter substrate-binding protein LsrB	NA	NA	NA	NA
WP_022645704.1\|1714290_1715166_+	3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase	NA	NA	NA	NA
WP_000558525.1\|1715189_1715480_+	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase	NA	NA	NA	NA
WP_022645705.1\|1715536_1716295_+	trans-aconitate 2-methyltransferase	NA	NA	NA	NA
WP_022645706.1\|1716298_1717213_-	bestrophin family protein	NA	NA	NA	NA
WP_022645707.1\|1717409_1718861_-	tagaturonate reductase	NA	NA	NA	NA
WP_022645708.1\|1719088_1720507_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.4e-18	36.1
WP_022645709.1\|1720645_1721005_-	DUF4186 domain-containing protein	NA	NA	NA	NA
WP_000257409.1\|1721004_1721931_-	glutaminase B	NA	NA	NA	NA
WP_000156623.1\|1721994_1723383_-	succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000366505.1\|1723483_1724365_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_022645710.1\|1724442_1725558_+	putative protein YneK	NA	NA	NA	NA
WP_000210799.1\|1725707_1726898_+	L-arabinose MFS transporter	NA	NA	NA	NA
WP_000885033.1\|1726922_1727588_-	NAAT family transporter MarC	NA	NA	NA	NA
WP_022645711.1\|1727799_1728234_+	multiple antibiotic resistance transcriptional regulator MarR	NA	NA	NA	NA
WP_000091199.1\|1728254_1728638_+	MDR efflux pump AcrAB transcriptional activator MarA	D0R0F8	Streptococcus_phage	4.7e-09	32.3
WP_000803527.1\|1728669_1728888_+	multiple antibiotic resistance protein MarB	NA	NA	NA	NA
WP_000087204.1\|1728918_1729818_-	O-acetylserine/cysteine exporter	NA	NA	NA	NA
WP_022645712.1\|1730012_1731200_+	efflux MFS transporter YdeE	NA	NA	NA	NA
WP_000901367.1\|1731326_1731422_+	protein MgtS	NA	NA	NA	NA
WP_000592819.1\|1731640_1732531_-	diguanylate cyclase DgcZ	A0A127AWB9	Bacillus_phage	1.4e-19	37.0
WP_022645713.1\|1732785_1733178_-	YdeI family stress tolerance OB fold protein	NA	NA	NA	NA
WP_022645714.1\|1733543_1735589_-	peptidyl-dipeptidase Dcp	NA	NA	NA	NA
WP_000636571.1\|1735725_1736472_+	bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG	NA	NA	NA	NA
WP_022645715.1\|1736560_1737247_+	DNA-binding transcriptional regulator YdfH	NA	NA	NA	NA
WP_000214712.1\|1737423_1737627_+	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2
WP_000527788.1\|1737662_1739123_-	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	6.6e-43	30.1
WP_120795384.1\|1741100_1741214_+	hypothetical protein	A0A1C9IHU6	Salmonella_phage	8.4e-07	80.6
WP_000836768.1\|1741282_1741516_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
WP_000086527.1\|1741832_1742423_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-24	38.8
WP_001546828.1\|1742650_1742944_-	hypothetical protein	NA	NA	NA	NA
WP_001546829.1\|1742986_1744027_-\|tail	tail fiber domain-containing protein	A0A0E3M4A9	Enterobacteria_phage	4.5e-155	80.5
WP_001546830.1\|1744037_1744316_-	hypothetical protein	A0A0E3GMJ7	Enterobacteria_phage	3.8e-24	54.3
WP_001546831.1\|1744312_1746685_-\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0E3M0V5	Enterobacteria_phage	4.1e-103	47.5
WP_001228249.1\|1746749_1747349_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	1.5e-102	92.0
WP_022645716.1\|1747416_1750896_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.3
WP_023277304.1\|1750956_1751604_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	4.7e-110	94.9
WP_001613114.1\|1753134_1754643_-\|portal	phage portal protein	A5LH29	Enterobacteria_phage	1.2e-286	99.2
WP_001072975.1\|1754642_1754855_-	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_000507029.1\|1754851_1756951_-\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	0.0e+00	99.0
WP_000421825.1\|1756959_1757499_-	DUF1441 family protein	A5LH26	Enterobacteria_phage	1.8e-94	100.0
WP_000548585.1\|1758049_1758256_-	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	7.6e-22	77.9
WP_023356416.1\|1758543_1758954_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	1.2e-55	78.5
WP_001082503.1\|1759273_1759738_-\|lysis	lysis protein	A0A0K2FJD0	Enterobacteria_phage	5.9e-62	84.2
WP_001274706.1\|1760036_1760570_-	lysozyme	Q08J98	Stx2-converting_phage	1.7e-97	95.5
WP_039052575.1\|1760625_1760940_-	YdfR family protein	K7PGU6	Enterobacteria_phage	5.4e-51	98.1
WP_000839561.1\|1760944_1761160_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	5.9e-33	95.8
WP_001348108.1\|1761411_1761786_-	hypothetical protein	NA	NA	NA	NA
WP_000506936.1\|1761957_1762386_-	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_029380182.1\|1762752_1762881_-	DUF3927 family protein	H6WZJ7	Escherichia_phage	4.7e-06	96.4
WP_000762866.1\|1763602_1764424_-	antitermination protein	K7P7B9	Enterobacteria_phage	1.2e-78	59.0
WP_000904112.1\|1764420_1764795_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	8.4e-35	62.7
WP_001695976.1\|1764807_1765857_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	2.7e-107	54.0
WP_001429486.1\|1765858_1766137_-	hypothetical protein	I6PCV7	Cronobacter_phage	4.3e-12	48.4
WP_000887491.1\|1766595_1766808_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.7e-29	97.1

DBSCAN-SWA_6

1769984 : 1786642

Escherichia_phage(33.33%)

lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032285383.1\|1769984_1770401_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.8e-62	90.3
WP_032285382.1\|1770441_1771512_-	phage replisome organizer	A0A088CD36	Shigella_phage	7.4e-52	56.1
WP_032285381.1\|1771583_1772009_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001072337.1\|1772005_1772260_-	hypothetical protein	A0A2I6PIE5	Escherichia_phage	2.8e-18	60.3
WP_000233320.1\|1772339_1772759_+	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	4.2e-19	47.5
WP_032154077.1\|1773056_1773212_+	DUF1391 family protein	M4QQ57	Salicola_phage	3.4e-06	51.1
WP_000344944.1\|1773213_1773789_+	hypothetical protein	NA	NA	NA	NA
WP_000854559.1\|1774275_1774464_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001083297.1\|1774460_1774652_+\|lysis	lysis protein YdfD	NA	NA	NA	NA
WP_069383057.1\|1774744_1777216_+	exonuclease	A0A192Y6E0	Salmonella_phage	8.5e-59	56.7
WP_000005552.1\|1777288_1777540_+	excisionase family protein	S4TND0	Salmonella_phage	2.2e-15	50.0
WP_000876985.1\|1777574_1778855_+	DUF3596 domain-containing protein	B6DZ48	Enterobacteria_phage	1.7e-156	62.6
WP_001389342.1\|1778856_1778985_-	hypothetical protein	NA	NA	NA	NA
WP_000836037.1\|1779042_1780062_-	Zn-dependent oxidoreductase	E3SJ82	Synechococcus_phage	4.3e-17	26.2
WP_001295394.1\|1780073_1781288_-	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	1.4e-46	29.0
WP_001304355.1\|1781493_1781820_-	YnfA family protein	A0A218MNG8	uncultured_virus	2.9e-23	54.5
WP_000705197.1\|1781954_1782296_+	DUF1283 family protein	NA	NA	NA	NA
WP_001138584.1\|1782330_1782891_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_001445899.1\|1782893_1783604_-	YnfC family lipoprotein	NA	NA	NA	NA
WP_001295396.1\|1783711_1784017_+	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_022645727.1\|1784215_1786642_+	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	1.7e-213	49.2

DBSCAN-SWA_7

2329439 : 2338155

Enterobacteria_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000735124.1\|2329439_2330567_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAI1	Catovirus	5.3e-32	30.4
WP_001362820.1\|2330576_2331815_-	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_001100791.1\|2331846_2332395_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	4.2e-51	56.1
WP_000857549.1\|2332399_2333278_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.5e-106	64.1
WP_001023627.1\|2333335_2334235_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.5e-29	35.6
WP_000699418.1\|2334234_2335320_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.4e-101	54.2
WP_000183060.1\|2335692_2336586_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_001116131.1\|2336760_2338155_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	2.8e-19	31.9

DBSCAN-SWA_8

2431707 : 2441149

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001329822.1\|2431707_2432844_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	4.2e-162	97.4
WP_022645869.1\|2432840_2434841_+	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.8
WP_022645870.1\|2434965_2435427_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	3.5e-75	98.7
WP_001295430.1\|2435467_2435938_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_012311742.1\|2435984_2436704_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001334139.1\|2436700_2438386_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	9.5e-304	99.5
WP_001240398.1\|2438607_2439339_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.8e-111	99.0
WP_001216963.1\|2439398_2439506_+	protein YohO	NA	NA	NA	NA
WP_022645871.1\|2439486_2440218_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_022645872.1\|2440222_2441149_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	2.2e-23	30.8

DBSCAN-SWA_9

3712613 : 3768103

uncultured_Caudovirales_phage(50.0%)

tail,tRNA,head,terminase,capsid,portal,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000366126.1\|3712613_3713111_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	2.5e-26	54.8
WP_000257293.1\|3713116_3713755_-	stringent starvation protein A	NA	NA	NA	NA
WP_000829818.1\|3714148_3714541_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_000847559.1\|3714556_3714985_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_001190805.1\|3715203_3716331_-	cell division protein ZapE	NA	NA	NA	NA
WP_001295270.1\|3716524_3716923_+	DUF1043 family protein	NA	NA	NA	NA
WP_001295271.1\|3717076_3718444_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	2.3e-21	25.6
WP_000497723.1\|3718533_3719601_+	outer membrane-stress sensor serine endopeptidase DegS	A0A1S5Y2X3	uncultured_archaeal_virus	6.8e-05	24.2
WP_001315036.1\|3719663_3720602_-	malate dehydrogenase	NA	NA	NA	NA
WP_001257846.1\|3721036_3721507_+	transcriptional regulator ArgR	NA	NA	NA	NA
WP_000695690.1\|3721871_3722135_+	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_001029013.1\|3722191_3722464_-	barstar family protein	NA	NA	NA	NA
WP_000510964.1\|3722555_3724523_-	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_000854023.1\|3724528_3725461_-	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_000051841.1\|3725468_3725672_-	AaeX family protein	NA	NA	NA	NA
WP_000440317.1\|3725854_3726784_+	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
WP_021541362.1\|3726911_3728357_-\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_022646171.1\|3728512_3732313_-	AsmA2 domain-containing protein YhdP	NA	NA	NA	NA
WP_000123197.1\|3732380_3733850_-	ribonuclease G	NA	NA	NA	NA
WP_000203099.1\|3733839_3734433_-	nucleoside triphosphate pyrophosphatase YhdE	NA	NA	NA	NA
WP_000179409.1\|3734441_3734930_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_000802511.1\|3734929_3736033_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_000913396.1\|3736098_3737142_-	rod shape-determining protein MreB	F2Y0P3	Organic_Lake_phycodnavirus	6.7e-05	22.3
WP_022646172.1\|3737446_3739387_-	RNase E specificity factor CsrD	NA	NA	NA	NA
WP_022646173.1\|3739538_3740513_+	oxidoreductase	NA	NA	NA	NA
WP_000838294.1\|3740549_3741380_+	hypothetical protein	NA	NA	NA	NA
WP_000354622.1\|3742245_3742716_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_000884639.1\|3742726_3744076_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_000787055.1\|3744167_3745214_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_000048617.1\|3745210_3746173_-	sugar kinase	NA	NA	NA	NA
WP_000137049.1\|3746194_3747184_-	ABC transporter permease	NA	NA	NA	NA
WP_022646174.1\|3747184_3748684_-	sugar ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	4.7e-12	32.3
WP_001361192.1\|3748744_3749635_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_000275531.1\|3749670_3750525_-	tagatose bisphosphate family class II aldolase	NA	NA	NA	NA
WP_000843961.1\|3750866_3751697_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.2e-09	27.0
WP_032140302.1\|3751728_3752664_+	sugar kinase	NA	NA	NA	NA
WP_000381171.1\|3752756_3752999_+	YhdT family protein	NA	NA	NA	NA
WP_001175698.1\|3752988_3754440_+	sodium/pantothenate symporter	NA	NA	NA	NA
WP_001145812.1\|3754451_3755333_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_001219652.1\|3755661_3756627_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_000462905.1\|3756652_3756949_+	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_001449337.1\|3757730_3758012_-	hypothetical protein	NA	NA	NA	NA
WP_022646176.1\|3758017_3759679_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	1.2e-277	82.6
WP_001353110.1\|3759662_3760019_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	6.1e-51	83.8
WP_001251188.1\|3760138_3760324_-	hypothetical protein	NA	NA	NA	NA
WP_001145897.1\|3760307_3760748_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	9.1e-65	76.0
WP_001287546.1\|3760747_3761050_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	1.4e-27	61.1
WP_000270252.1\|3761042_3762257_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	7.5e-210	87.3
WP_000798770.1\|3762258_3762819_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	9.8e-88	84.4
WP_000733254.1\|3762873_3764043_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	6.7e-163	75.8
WP_022646177.1\|3764440_3765037_+	hypothetical protein	NA	NA	NA	NA
WP_000365446.1\|3765096_3765606_+	hypothetical protein	NA	NA	NA	NA
WP_001122065.1\|3765640_3765901_-	hypothetical protein	NA	NA	NA	NA
WP_001553503.1\|3766285_3768103_-	hypothetical protein	Q7M2A8	Enterobacteria_phage	1.7e-128	47.9

DBSCAN-SWA_10

4661931 : 4678452

Burkholderia_phage(33.33%)

plate,holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022646405.1\|4661931_4662723_+	nucleotidyltransferase domain-containing protein	A0A2D1GQQ2	Pseudomonas_phage	2.0e-46	45.1
WP_022646406.1\|4662736_4663192_-	hypothetical protein	F6MIM0	Haemophilus_phage	6.6e-26	42.7
WP_022646407.1\|4663188_4663896_-	DUF4376 domain-containing protein	A0A0E3JQ06	Enterobacteria_phage	5.3e-14	42.4
WP_022646408.1\|4663892_4665503_-\|tail	phage tail protein	A0A0M3ULH6	Salmonella_phage	3.8e-84	39.1
WP_022646409.1\|4665505_4666222_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	3.1e-22	37.2
WP_022646410.1\|4666214_4667330_-\|plate	baseplate J/gp47 family protein	Q6QI99	Burkholderia_phage	2.0e-100	51.7
WP_022646411.1\|4667320_4667680_-	GPW/gp25 family protein	Q6QIA0	Burkholderia_phage	1.1e-34	64.2
WP_000679403.1\|4667778_4668480_-\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	6.4e-12	36.3
WP_022646412.1\|4668489_4669530_-	phage late control D family protein	A4JWL3	Burkholderia_virus	2.0e-73	45.1
WP_001269711.1\|4669517_4669727_-\|tail	tail protein X	A4JWL2	Burkholderia_virus	1.3e-16	60.3
WP_022646413.1\|4669726_4670680_-\|tail	phage tail protein	A4JWL1	Burkholderia_virus	3.3e-35	50.8
WP_022646414.1\|4670679_4673055_-	hypothetical protein	A4JWL0	Burkholderia_virus	1.0e-56	26.0
WP_015674804.1\|4673156_4673285_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_022646415.1\|4673244_4673562_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_000907502.1\|4673612_4674137_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	9.5e-69	69.0
WP_022646416.1\|4674136_4675561_-\|tail	phage tail sheath family protein	A4JWK5	Burkholderia_virus	7.0e-191	70.2
WP_000875310.1\|4675550_4675748_-	hypothetical protein	NA	NA	NA	NA
WP_022646417.1\|4675744_4676200_-	hypothetical protein	NA	NA	NA	NA
WP_000777272.1\|4676344_4676659_-	membrane protein	Q5ZQY8	Pseudomonas_phage	9.2e-19	43.2
WP_000266448.1\|4676671_4677277_-	lytic transglycosylase domain-containing protein	Q5ZQZ1	Pseudomonas_phage	3.3e-57	57.1
WP_022646418.1\|4677279_4677567_-\|holin	putative holin	Q6QIC8	Burkholderia_phage	3.9e-16	48.6
WP_000619864.1\|4678104_4678452_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	2.2e-21	49.0

DBSCAN-SWA_11

4707697 : 4753872

Enterobacteria_phage(56.25%)

tail,integrase,tRNA,terminase,lysis,portal,protease

attL 4729301:4729315|attR 4756222:4756236

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000390072.1\|4707697_4707871_+	hypothetical protein	K7PJQ2	Enterobacteria_phage	9.8e-23	98.2
WP_001093918.1\|4707918_4708200_-	pyocin activator PrtN family protein	K7PGU0	Enterobacteria_phage	8.7e-45	98.9
WP_001061348.1\|4708236_4708809_-	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	1.2e-109	99.5
WP_039052442.1\|4708808_4709612_-	DUF551 domain-containing protein	K7PH57	Enterobacteria_phage	5.4e-79	94.0
WP_001151811.1\|4709615_4709765_-	hypothetical protein	NA	NA	NA	NA
WP_024190088.1\|4709766_4710354_-	hypothetical protein	Q9MCT8	Escherichia_phage	4.9e-98	76.4
WP_000008179.1\|4710344_4710881_-	5'-deoxynucleotidase	A0A0P0ZCH9	Stx2-converting_phage	1.2e-98	98.3
WP_039052441.1\|4711008_4711833_-	DUF2303 family protein	U5P439	Shigella_phage	5.0e-149	99.3
WP_039052440.1\|4711898_4712261_-	hypothetical protein	Q8SBF8	Shigella_phage	4.9e-56	94.2
WP_000357060.1\|4712722_4713226_+	hypothetical protein	A0A077K9U2	Edwardsiella_phage	1.2e-31	47.6
WP_000450740.1\|4713593_4714220_-	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	3.2e-47	48.8
WP_032353353.1\|4714317_4714518_+	cell division protein	NA	NA	NA	NA
WP_000514174.1\|4714555_4715140_+	hypothetical protein	A0A1C9II13	Salmonella_phage	5.5e-57	60.9
WP_001250270.1\|4715315_4715528_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	5.4e-15	68.5
WP_039052439.1\|4715484_4716477_+	hypothetical protein	U5P0A0	Shigella_phage	1.4e-92	97.6
WP_039052438.1\|4716571_4717225_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.1e-127	100.0
WP_000210187.1\|4717221_4717548_+	LexA family transcriptional regulator	A5LH73	Enterobacteria_phage	1.6e-53	100.0
WP_000767134.1\|4717544_4717934_+	RusA family crossover junction endodeoxyribonuclease	A5LH74	Enterobacteria_phage	3.2e-69	100.0
WP_001061445.1\|4717953_4718763_+	KilA-N domain-containing protein	A0A291AWU7	Escherichia_phage	4.0e-151	99.6
WP_001433852.1\|4718770_4719760_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.9e-195	99.7
WP_039052437.1\|4719773_4720526_+	antitermination protein	Q8SBE4	Shigella_phage	7.6e-136	98.4
WP_039052436.1\|4720806_4721232_+	hypothetical protein	A0A291AWZ9	Escherichia_phage	3.0e-73	97.9
WP_000917724.1\|4721455_4721659_+	hypothetical protein	A0A291AWX6	Escherichia_phage	6.1e-32	100.0
WP_021521156.1\|4721809_4722862_+	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	6.1e-208	99.7
WP_000839596.1\|4722929_4723145_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_001529529.1\|4723149_4723500_+	YdfR family protein	K7PGU6	Enterobacteria_phage	6.4e-37	94.0
WP_001529530.1\|4723563_4724097_+	lysozyme	K7PLY1	Enterobacteria_phage	1.3e-100	97.2
WP_001300226.1\|4724093_4724561_+\|lysis	lysis protein	K7PH77	Enterobacteria_phage	2.9e-77	100.0
WP_001139681.1\|4724548_4724701_+	hypothetical protein	K7PKL2	Enterobacteria_phage	4.7e-21	96.0
WP_001205135.1\|4724842_4725019_-	hypothetical protein	NA	NA	NA	NA
WP_000421825.1\|4725374_4725914_+	DUF1441 family protein	A5LH26	Enterobacteria_phage	1.8e-94	100.0
WP_000507030.1\|4725922_4728022_+\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	0.0e+00	99.4
WP_001072975.1\|4728018_4728231_+	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_001529531.1\|4728230_4729739_+\|portal	phage portal protein	K7PJP3	Enterobacteria_phage	2.3e-288	99.2
4729301:4729315	attL	NA	NA	NA	NA
WP_001136590.1\|4729683_4731711_+\|protease	Clp protease ClpP	A5LH30	Enterobacteria_phage	0.0e+00	99.5
WP_001097055.1\|4731797_4732121_+	DUF2190 family protein	A0A291AWX2	Escherichia_phage	2.5e-51	99.1
WP_001283153.1\|4732113_4732389_+	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	2.3e-45	100.0
WP_069383065.1\|4732400_4732991_+\|tail	phage tail protein	A5LH33	Enterobacteria_phage	9.4e-81	79.6
WP_001079398.1\|4732987_4733389_+\|tail	tail protein	A0A291AWY2	Escherichia_phage	8.3e-73	100.0
WP_000211088.1\|4733400_4734144_+\|tail	phage tail protein	A0A291AWU6	Escherichia_phage	3.0e-132	99.6
WP_001398454.1\|4734204_4734591_+\|tail	phage minor tail protein G	A5LH36	Enterobacteria_phage	2.3e-64	97.7
WP_001161009.1\|4734599_4734929_+\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.6e-56	100.0
WP_039052374.1\|4739008_4739752_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	4.7e-146	95.1
WP_069383066.1\|4740355_4743835_+	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.2
WP_001228228.1\|4743902_4744502_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	1.2e-102	93.0
WP_069383067.1\|4744566_4746915_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0E3M0V5	Enterobacteria_phage	9.5e-92	46.3
WP_022646431.1\|4746911_4747193_+	hypothetical protein	A0A1X7QHA1	Escherichia_phage	4.1e-18	50.0
WP_001595444.1\|4747202_4747907_+\|tail	tail fiber domain-containing protein	A0A1X7QGH6	Escherichia_phage	7.0e-59	61.7
WP_022646432.1\|4747917_4748205_+	hypothetical protein	NA	NA	NA	NA
WP_001217539.1\|4748315_4748564_-	DinI-like family protein	A5LH55	Enterobacteria_phage	1.1e-38	100.0
WP_000332260.1\|4748625_4749723_-\|integrase	site-specific integrase	S5MDN5	Escherichia_phage	4.0e-210	99.2
WP_077877367.1\|4749811_4750849_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_000891408.1\|4750982_4751225_+	envelope stress response protein PspG	NA	NA	NA	NA
WP_022646433.1\|4751390_4752374_-	quinone oxidoreductase	NA	NA	NA	NA
WP_000918363.1\|4752456_4753872_+	replicative DNA helicase	O80281	Escherichia_phage	4.8e-200	78.3
4756222:4756236	attR	NA	NA	NA	NA

DBSCAN-SWA_12

4947613 : 5016452

Vibrio_phage(20.0%)

holin,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001162175.1\|4947613_4948966_+\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_001232240.1\|4949148_4949535_+	cytochrome b562	NA	NA	NA	NA
WP_001106222.1\|4949579_4950044_-	anaerobic ribonucleoside-triphosphate reductase-activating protein	H6WXC9	Vibrio_phage	1.1e-52	59.7
WP_000187778.1\|4950201_4952340_-	anaerobic ribonucleoside-triphosphate reductase	A0A2I7QNQ7	Vibrio_phage	1.5e-266	64.5
WP_001339491.1\|4952733_4954389_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_001299664.1\|4954438_4955860_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_001181324.1\|4955978_4956926_-	HTH-type transcriptional regulator TreR	C6ZCU4	Enterobacteria_phage	7.9e-13	21.8
WP_001387276.1\|4957110_4957164_+	mgtA regulatory leader peptide MgtL	NA	NA	NA	NA
WP_000471889.1\|4957303_4960000_+	magnesium-translocating P-type ATPase	M1HLC0	Paramecium_bursaria_Chlorella_virus	9.0e-46	27.4
WP_000047538.1\|4960205_4960592_-	2-iminobutanoate/2-iminopropanoate deaminase	NA	NA	NA	NA
WP_000148581.1\|4960664_4961126_-	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_000013046.1\|4961138_4962074_-	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	2.9e-52	40.2
WP_001296693.1\|4962077_4962212_-	pyr operon leader peptide	NA	NA	NA	NA
WP_000230277.1\|4962492_4962888_-	RidA family protein	NA	NA	NA	NA
WP_000500725.1\|4963018_4963732_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000256670.1\|4963802_4964396_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001353502.1\|4964540_4964993_+	toxin-antitoxin biofilm protein TabA	NA	NA	NA	NA
WP_000036525.1\|4965115_4966090_+	hypothetical protein	NA	NA	NA	NA
WP_001309157.1\|4966105_4966459_+	hypothetical protein	NA	NA	NA	NA
WP_001309158.1\|4966445_4966676_+	hypothetical protein	NA	NA	NA	NA
WP_000012907.1\|4966776_4967781_-	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_000002953.1\|4967942_4968359_+	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_001059422.1\|4968404_4968908_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000079641.1\|4969100_4970297_+	DUF898 domain-containing protein	NA	NA	NA	NA
WP_000416382.1\|4970352_4973208_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.3e-140	36.7
WP_000786399.1\|4973207_4973651_-	DNA polymerase III subunit chi	NA	NA	NA	NA
WP_000397144.1\|4973906_4975418_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	6.0e-47	38.0
WP_000584114.1\|4975684_4976785_+	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_001295681.1\|4976784_4977867_+	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_001294573.1\|4978027_4979530_-	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	4.6e-84	44.2
WP_001309159.1\|4979607_4980606_-	DNA-binding transcriptional regulator IdnR	NA	NA	NA	NA
WP_069383069.1\|4980672_4981992_-	gnt-II system L-idonate transporter	NA	NA	NA	NA
WP_000998695.1\|4982053_4982818_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_001197411.1\|4982841_4983873_-	L-idonate 5-dehydrogenase	NA	NA	NA	NA
WP_000896738.1\|4984089_4984653_+	gluconokinase	NA	NA	NA	NA
WP_001309160.1\|4984656_4985676_-	NADPH-dependent aldehyde reductase Ahr	A0A0G2Y405	Acanthamoeba_polyphaga_mimivirus	1.1e-44	30.7
WP_000050905.1\|4990062_4990206_+	hypothetical protein	NA	NA	NA	NA
WP_000483767.1\|4990233_4991580_-\|transposase	IS4-like element IS4 family transposase	NA	NA	NA	NA
WP_000179691.1\|4992188_4993406_+	MFS transporter	NA	NA	NA	NA
WP_000611568.1\|4993417_4994536_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_000594405.1\|4994578_4994704_+	hypothetical protein	NA	NA	NA	NA
WP_000254999.1\|4994756_4995014_-	hypothetical protein	NA	NA	NA	NA
WP_085948656.1\|4995327_4996494_+\|transposase	IS3-like element IS911 family transposase	Q716C2	Shigella_phage	1.8e-184	99.3
WP_000625671.1\|4996429_4996843_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_001293436.1\|4996905_4998903_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	7.4e-21	25.9
WP_001254932.1\|4999959_5001111_-\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-42	35.6
WP_000177057.1\|5002369_5002627_+	hypothetical protein	NA	NA	NA	NA
WP_000175457.1\|5003183_5003951_-	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
WP_000684852.1\|5003951_5004908_-	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	8.2e-18	26.1
WP_000125187.1\|5004904_5005903_-	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_000879155.1\|5005899_5006802_-	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_000188283.1\|5006846_5009171_-	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_001068910.1\|5009257_5010211_-	fec operon regulator FecR	NA	NA	NA	NA
WP_001283626.1\|5010207_5010729_-	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_000555337.1\|5012479_5012737_+	hypothetical protein	NA	NA	NA	NA
WP_000823243.1\|5013469_5014828_+	esterase-like activity of phytase family protein	NA	NA	NA	NA
WP_000998017.1\|5015066_5016452_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	6.9e-260	89.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP015836

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

38555 : 80357

Escherichia_phage(25.0%)

integrase,transposase

attL 39724:39783|attR 88164:89384

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061856962.1\|38555_39773_-\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	2.0e-226	100.0
39724:39783	attL	NA	NA	NA	NA
WP_087758690.1\|39794_40914_+\|transposase	IS3-like element ISSen4 family transposase	S5WIU1	Leptospira_phage	1.7e-51	42.8
WP_039052454.1\|41898_42675_+	hypothetical protein	NA	NA	NA	NA
WP_039052447.1\|42676_44941_+	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_039052448.1\|45283_46264_+\|transposase	IS5 family transposase	A0A077SK28	Escherichia_phage	2.9e-180	97.2
WP_039052449.1\|47772_48165_-	plasmid partitioning/stability family protein	NA	NA	NA	NA
WP_039052450.1\|48169_49141_-	plasmid segregation protein parM	A0A222YXF2	Escherichia_phage	9.7e-67	42.6
WP_000633913.1\|49369_50014_+	AAA family ATPase	A0A222YXS3	Escherichia_phage	1.9e-39	43.0
WP_000239529.1\|50007_50283_+	hypothetical protein	NA	NA	NA	NA
WP_157916581.1\|50902_51142_-	resolvase	NA	NA	NA	NA
WP_039052451.1\|51248_51857_-	hypothetical protein	NA	NA	NA	NA
WP_039052452.1\|51926_52277_-	hypothetical protein	NA	NA	NA	NA
WP_000246635.1\|52954_53950_+	hypothetical protein	NA	NA	NA	NA
WP_000991831.1\|53953_54886_+	hypothetical protein	NA	NA	NA	NA
WP_001586223.1\|55178_55364_+	hypothetical protein	NA	NA	NA	NA
WP_024187432.1\|55364_56267_+	hypothetical protein	NA	NA	NA	NA
WP_001586225.1\|56268_57138_+	hypothetical protein	NA	NA	NA	NA
WP_001586226.1\|57194_58760_-	ATP-binding protein	NA	NA	NA	NA
WP_001586228.1\|59046_59559_+	hypothetical protein	NA	NA	NA	NA
WP_000545985.1\|59592_60726_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_001403958.1\|61693_62179_-	hypothetical protein	NA	NA	NA	NA
WP_001586230.1\|62569_65191_+	hypothetical protein	A0A1B1IUG5	uncultured_Mediterranean_phage	5.9e-18	23.7
WP_001261274.1\|65389_65620_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_001403920.1\|65708_65984_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_000348883.1\|66206_66737_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001275013.1\|66740_67010_-	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_123002471.1\|67897_68887_+	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	2.5e-102	63.7
WP_001586233.1\|69209_69950_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	56.9
WP_042004909.1\|70070_70253_-	hypothetical protein	NA	NA	NA	NA
WP_001440647.1\|70319_70481_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_029702141.1\|71160_71901_-\|integrase	tyrosine-type recombinase/integrase	I3WFA4	Macacine_betaherpesvirus	1.6e-24	57.6
WP_029702172.1\|72853_73303_-	hypothetical protein	NA	NA	NA	NA
WP_000027057.1\|76930_77791_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|77973_78531_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000608644.1\|79094_80357_+\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
88164:89384	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015837

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP015834

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP015836

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection