CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017305	Chlorobaculum limnaeum strain DSM 1677 chromosome, complete genome	6 crisprs	cas3,cas2,cas1,csx1,csx15,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,DEDDh,cas7,cas8c,cas5,csa3,Cas9_archaeal,cas8e,cse2gr11,cas6e	0	5	2	0

1. NZ_CP017305

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017305_1

• CRISPR_ID: NZ_CP017305_1
• CRISPR_location: 1044895-1045749
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 11 spacers
• Cas_protein_info: cas2,cas1,csx1,csx15,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7

Consensus repeat of NZ_CP017305_1

Consensus_repeat	Method
CATCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACT	PILER-CR
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CRISPRCasFinder
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CRT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	PILER-CR

spacers of NZ_CP017305_1

>1.1|1044934|36|NZ_CP017305|PILER-CR
AATCATGTTTTGGAGCCTTGCTCCAGTAATCTACAT
>1.2|1045009|34|NZ_CP017305|PILER-CR
GGGAACGCATCTCCTACAATTTCAGCTATCCCCG
>1.3|1044931|40|NZ_CP017305|CRISPRCasFinder,CRT
TAATCATGTTTTGGAGCCTTGCTCCAGTAATCTACATCAA
>1.4|1045006|38|NZ_CP017305|CRISPRCasFinder,CRT
CGGGAACGCATCTCCTACAATTTCAGCTATCCCCGCAT
>1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT
TTCAGAGATAATAAATATCTTTTTAAACATTATACTT
>1.6|1045151|47|NZ_CP017305|CRISPRCasFinder,CRT
TTGTAGATTAGCCACCATTCTTGATAGATCAGACGTCCGTTTTTTTC
>1.7|1045233|36|NZ_CP017305|CRISPRCasFinder,CRT,PILER-CR
TCAAGTATCTCCTCGTATGTACCCACAATATCACTT
>1.8|1045304|42|NZ_CP017305|CRISPRCasFinder,CRT,PILER-CR
GAAATTCTCTTGCATCTTTTACTGTAAAGTTTCTATTAGCAG
>1.9|1045381|39|NZ_CP017305|CRISPRCasFinder,CRT,PILER-CR
GGCTTGCGTTCCCACGTTTTCAGCGACCATGGCATATGA
>1.10|1045455|40|NZ_CP017305|CRISPRCasFinder,CRT,PILER-CR
CAAGCGCATTCCGCGTCTGTCCATGGGCCATACGTGAATC
>1.11|1045530|39|NZ_CP017305|CRISPRCasFinder,CRT,PILER-CR
GGTCGTATGACGAAAAGTCTTCCGAAGTCCGGTAAGATT
>1.12|1045604|39|NZ_CP017305|CRISPRCasFinder,CRT,PILER-CR
TTTTTCCTGACTGTCACGCTTCGTGCAATACAGCGCGGC
>1.13|1045678|37|NZ_CP017305|CRISPRCasFinder,CRT
TTTTTTCCCGATCCTCGGTACGATCCGCGACCAGCTC

CRISPR arrays and Neighbor proteins around NZ_CP017305_1

CRISPR arrays

The CRISPR arrays of NZ_CP017305_1

>merge|NZ_CP017305|1|1044895-1045749|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
TCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTAATCATGTTTTGGAGCCTTGCTCCAGTAATCTACATCAACTTTATAGCTTATTGCACTCGCAGAGGATTGAAACCGGGAACGCATCTCCTACAATTTCAGCTATCCCCGCATCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTCAGAGATAATAAATATCTTTTTAAACATTATACTTCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTGTAGATTAGCCACCATTCTTGATAGATCAGACGTCCGTTTTTTTCCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTCAAGTATCTCCTCGTATGTACCCACAATATCACTTCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACGAAATTCTCTTGCATCTTTTACTGTAAAGTTTCTATTAGCAGCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACGGCTTGCGTTCCCACGTTTTCAGCGACCATGGCATATGACTTTATAGCTTATTGCACTCGCAGAGGATTGAAACCAAGCGCATTCCGCGTCTGTCCATGGGCCATACGTGAATCCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACGGTCGTATGACGAAAAGTCTTCCGAAGTCCGGTAAGATTCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTTTTCCTGACTGTCACGCTTCGTGCAATACAGCGCGGCCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTTTTTCCCGATCCTCGGTACGATCCGCGACCAGCTCCTTTATAGCTTATTGCACTCGCAGAGGATTTTCGT

>NZ_CP017305|1|1|1044895-1045079|PILER-CR
TCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTAA	TCATGTTTTGGAGCCTTGCTCCAGTAATCTACATCA
ACTTTATAGCTTATTGCACTCGCAGAGGATTGAAACCGG	GAACGCATCTCCTACAATTTCAGCTATCCCCGCA
TCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTCAGAGATAATAAATATCTTTTTAAACATTATACTTCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTGTAGATTAGCCACCATTCTTGATAGATCAGACGTCCGTTTTTTTCCTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TCAAGTATCTCCTCGTATGTACCCACAATATCACTT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GAAATTCTCTTGCATCTTTTACTGTAAAGTTTCTATTAGCAG
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGCTTGCGTTCCCACGTTTTCAGCGACCATGGCATATGA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CAAGCGCATTCCGCGTCTGTCCATGGGCCATACGTGAATC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGTCGTATGACGAAAAGTCTTCCGAAGTCCGGTAAGATT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTTTTCCTGACTGTCACGCTTCGTGCAATACAGCGCGGC


>NZ_CP017305|1|1|1044896-1045749|CRISPRCasFinder
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TAATCATGTTTTGGAGCCTTGCTCCAGTAATCTACATCAA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CGGGAACGCATCTCCTACAATTTCAGCTATCCCCGCAT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTCAGAGATAATAAATATCTTTTTAAACATTATACTT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTGTAGATTAGCCACCATTCTTGATAGATCAGACGTCCGTTTTTTTC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TCAAGTATCTCCTCGTATGTACCCACAATATCACTT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GAAATTCTCTTGCATCTTTTACTGTAAAGTTTCTATTAGCAG
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGCTTGCGTTCCCACGTTTTCAGCGACCATGGCATATGA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CAAGCGCATTCCGCGTCTGTCCATGGGCCATACGTGAATC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGTCGTATGACGAAAAGTCTTCCGAAGTCCGGTAAGATT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTTTTCCTGACTGTCACGCTTCGTGCAATACAGCGCGGC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTTTTTCCCGATCCTCGGTACGATCCGCGACCAGCTC
CTTTATAGCTTATTGCACTCGCAGAGGATTTTCGT

>NZ_CP017305|1|1|1044896-1045749|CRT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TAATCATGTTTTGGAGCCTTGCTCCAGTAATCTACATCAA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CGGGAACGCATCTCCTACAATTTCAGCTATCCCCGCAT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTCAGAGATAATAAATATCTTTTTAAACATTATACTT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTGTAGATTAGCCACCATTCTTGATAGATCAGACGTCCGTTTTTTTC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TCAAGTATCTCCTCGTATGTACCCACAATATCACTT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GAAATTCTCTTGCATCTTTTACTGTAAAGTTTCTATTAGCAG
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGCTTGCGTTCCCACGTTTTCAGCGACCATGGCATATGA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CAAGCGCATTCCGCGTCTGTCCATGGGCCATACGTGAATC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGTCGTATGACGAAAAGTCTTCCGAAGTCCGGTAAGATT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTTTTCCTGACTGTCACGCTTCGTGCAATACAGCGCGGC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTTTTTCCCGATCCTCGGTACGATCCGCGACCAGCTC
CTTTATAGCTTATTGCACTCGCAGAGGATTTTCGT

>NZ_CP017305|1|2|1045198-1045677|PILER-CR
	TCATGTTTTGGAGCCTTGCTCCAGTAATCTACATCA
ACTTTATAGCTTATTGCACTCGCAGAGGATTGAAACCGG	GAACGCATCTCCTACAATTTCAGCTATCCCCGCA
TCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTCAGAGATAATAAATATCTTTTTAAACATTATACTTCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTTGTAGATTAGCCACCATTCTTGATAGATCAGACGTCCGTTTTTTTCCTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TCAAGTATCTCCTCGTATGTACCCACAATATCACTT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GAAATTCTCTTGCATCTTTTACTGTAAAGTTTCTATTAGCAG
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGCTTGCGTTCCCACGTTTTCAGCGACCATGGCATATGA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CAAGCGCATTCCGCGTCTGTCCATGGGCCATACGTGAATC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GGTCGTATGACGAAAAGTCTTCCGAAGTCCGGTAAGATT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TTTTTCCTGACTGTCACGCTTCGTGCAATACAGCGCGGC
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017305.1|WP_069809197.1|1041861_1042416_-|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl|CDD|129813
NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl|CDD|367635
NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl|CDD|187811
NZ_CP017305.1|WP_069809196.1|1040315_1041560_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809195.1|1039681_1040041_-|GTPase	unknown	unknown	unknown
NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein	csx1	pfam09670_csx1_CAS-III	gnl|CDD|378236
NZ_CP017305.1|WP_069809192.1|1037588_1038164_+|DUF134-domain-containing-protein	unknown	unknown	gnl|CDD|224261
NZ_CP017305.1|WP_069809200.1|1043494_1044493_-|chlorophyll-synthase-ChlG	unknown	unknown	gnl|CDD|236052
NZ_CP017305.1|WP_069809198.1|1042412_1043066_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997
NZ_CP017305.1|WP_069809194.1|1038655_1039681_+|zinc-dependent-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|176258
NZ_CP017305.1|WP_157098344.1|1036429_1037398_+|bifunctional-methionine-sulfoxide-reductase-B/A-protein	unknown	unknown	gnl|CDD|235499
NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|273866
NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP017305.1|WP_069809199.1|1043078_1043498_-|YjbQ-family-protein	unknown	unknown	gnl|CDD|223509
NZ_CP017305.1|WP_157098345.1|1057110_1057596_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809193.1|1038160_1038529_+|dinitrogenase-iron-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238431
NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	gnl|CDD|187735
NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl|CDD|273863

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	2.1e-18	61.6	1.0
NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	7.7e-60	197.0	0.4
NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	5.9e-35	115.6	0.0
NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.5e-87	288.3	0.0
NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein	csx1	pfam09670_csx1_CAS-III	2.5e-11	37.8	0.0
NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	9.3e-28	91.0	0.3
NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	2.3e-89	295.3	0.1
NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	5.9e-36	117.0	0.0
NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	2.7e-12	41.3	14.9

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017305.1|WP_069809197.1|1041861_1042416_-|TIGR00730-family-Rossman-fold-protein	gnl|CDD|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	6.80562e-56
NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	3.15696e-20
NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	6.82271e-92
NZ_CP017305.1|WP_069809200.1|1043494_1044493_-|chlorophyll-synthase-ChlG	gnl|CDD|236052	PRK07566, PRK07566, chlorophyll synthase ChlG.	7.7271e-156
NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein	gnl|CDD|378236	pfam09670, Cas_Cas02710, CRISPR-associated protein (Cas_Cas02710). Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	2.6275e-06
NZ_CP017305.1|WP_069809192.1|1037588_1038164_+|DUF134-domain-containing-protein	gnl|CDD|224261	COG1342, COG1342, Predicted DNA-binding proteins [General function prediction only].	2.24334e-26
NZ_CP017305.1|WP_069809198.1|1042412_1043066_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	8.92537e-32
NZ_CP017305.1|WP_069809194.1|1038655_1039681_+|zinc-dependent-alcohol-dehydrogenase-family-protein	gnl|CDD|176258	cd08298, CAD2, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.94244e-171
NZ_CP017305.1|WP_157098344.1|1036429_1037398_+|bifunctional-methionine-sulfoxide-reductase-B/A-protein	gnl|CDD|235499	PRK05550, PRK05550, bifunctional methionine sulfoxide reductase B/A protein; Provisional.	0
NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.06917e-62
NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	1.88041e-33
NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.38067e-104
NZ_CP017305.1|WP_069809199.1|1043078_1043498_-|YjbQ-family-protein	gnl|CDD|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	1.21775e-48
NZ_CP017305.1|WP_069809193.1|1038160_1038529_+|dinitrogenase-iron-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238431	cd00851, MTH1175, This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).	6.0794e-23
NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.56749e-30
NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein	gnl|CDD|187735	cd09766, Csx15_I-U, CRISPR/Cas system-associated protein Csx15. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein loosely associated with CRISPR/Cas systems; some are fused to AAA ATPase domain, also known as TTE2665 family.	5.27135e-37
NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein	gnl|CDD|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	0.000102351

Protein sequences

>NZ_CP017305.1|WP_069809200.1|1043494_1044493_-|chlorophyll-synthase-ChlG
MAGAETQERQESGKAANGEKGALNVRKMVPPQNRSSEPLTSLRLFVRFLKPVTWIPVVWSFVCGAVASGAFGWREVGSVKFLLAVLLTGPLATGTCQMLNDYFDRDLDEINEPNRPIPGGAISLRSATMLIALWSVLSVLVGWLVHPLIALYVVIGIINAHLYSANPIKLKKRLWAGNIIVAVSYLIIPWVAGEIAYRPDFSLQAITPSLIVAALYTIASTGTMTINDFKSIEGDRQVGIHTLPAVFGERKAALIAAVMIDLGQLMAAGYMFMIGEPTYGWVTALLVVPQFLLQFSLVRSPRTWDVRYNAIAQNFLVAGMMVCAFAIKSIEP
>NZ_CP017305.1|WP_069809199.1|1043078_1043498_-|YjbQ-family-protein
MTCGDTISLESRGFSEIHDITPEVRRIVAKSGVRSGIVTISAIGSTASVTTMEFEPALVEDFREKLQQLFPSTERSRHSETWGDDNGFSHMRASFMGPAVTLPVSGGEPVLGTWQQIVFIDHDNRPRSREIFMQLVGEP
>NZ_CP017305.1|WP_069809198.1|1042412_1043066_-|glycosyltransferase-family-2-protein
MQTPHFDLRPAISVILPTFDRAPLLAHAIESVVAQSFAEWELIVVDDGSSDDTFAVVDAFLRQHGNIRYMKHRNRKAALSRNAGIQASFGRYVTFLDSDDLYLPEHLESRFRMLEAMPETTLLSGGFVCEGDPWVRDRNDPGQWIHVRECIAGATMFGRRELFMELGGFQALDYAEDTDLWERASQRFRVLKIDQPESYIYRRSPDSITRTYKQTPS
>NZ_CP017305.1|WP_069809197.1|1041861_1042416_-|TIGR00730-family-Rossman-fold-protein
MIRSVTVYCSSSNRAPDPYFNEAEALGRGLAERKIGMVFGGGHVGLMGCAADAVMRCGGQVRGVIPRFLEEREVAHYGLTELRVVETMHERKMLLTGWADAFVILPGGFGTLDEFLEILTWKHLGHHEKPIILLNVDGFWDQLLQFFERIAKEKMVGESYRAFYDVCDSAEEALALIDRHNASV
>NZ_CP017305.1|WP_069809196.1|1040315_1041560_+|hypothetical-protein
MKPIRIDDYCFDRIHLWLQYDACVPQFIEMVVEVFYPANRKANGLVMFDHGFLIGNDLLWYPKKIAGMLLDDNPLFGINPSDYYNYSSALVEKNWAMAFVSASHAQVDWMPWTDIGGNPRVGQEAYAAASYLIKYGMTNFFWLVEAEGHNSRSFDAELASKAKFLISNNVIFAGHSVGGAHAQAAACGFDTLRQIGANQCRPFNPVIYNREFLPAFSMPMASWKEEHRANPVGLLMLSPVDQSVPLFIPGMSDYRAALASRPMPMAMITGQCDCACLDMSQPPAWSDNGTESQFSQLTGGGKGSWVVASQVERGSHCGYLTDKSPLCSVADMPSECKRCPEGTAYKPMGAEAVFTSEMFRKFIGIYPDGGGFQGGFSDWIQSDFITWLNQKSPCCDLNLMQMPGGGYIDNVPPV
>NZ_CP017305.1|WP_069809195.1|1039681_1040041_-|GTPase
MTTSLIFIYSTDSGTASALLDTGHKALSPSTYHCSLCELTQDTLGEKVRWREFRTSIGLPMEFFHRDEFERKYDLAFDYPVILRKNDKIEILLNKERIDKISNLDDLIDTIRQEMAKTA
>NZ_CP017305.1|WP_069809194.1|1038655_1039681_+|zinc-dependent-alcohol-dehydrogenase-family-protein
MNAMLLERVADLSHETQPLARRSLPVPEPGAGEILLRVGACGVCHTELDEIEGRTPPPRFPVIPGHQVVGSMVACGAGVTGIETGSRRGVAWIYSSCGHCDLCLSGHENLCADFRATGRDTDGGYAEYMVAPAAFTYPIPDLFTDAEAAPLLCGGAIGYRSLMLAGLRDGQILGLTGFGASGHQVLKLARYLYPASPVFVFARSEKDRDLARSLGADWAGDTTDAPPELCASIIDTTPAWLPVLAALERLRPGGRLVINAIRKENRDRELLAGISYERHLWMEKEIKSVANITRADVSTFLDIAARMELRPEVRCYPLGEANRVLLDLRHGRVTGAAVLVP
>NZ_CP017305.1|WP_069809193.1|1038160_1038529_+|dinitrogenase-iron-molybdenum-cofactor-biosynthesis-protein
MKIIIPLDEYSGPGSLVCDHFGSAPFFATVDMVGGEVKIIDNNNMHHDHGQCAPADSFADMGADAIVVKGIGARAAAKMQSLGIAIYMAGSAQRLIDVIEQFGSGILKKLDAQQACQGHGCH
>NZ_CP017305.1|WP_069809192.1|1037588_1038164_+|DUF134-domain-containing-protein
MPRPMKCRAIAQDPEHREFGPFCAGNRDAEPLVMSFDEFEAIRLADVEGLYQEEAARQMQVSRQTFGNILASARKKLGEMLVLGRMLNVTGGNIMVSQEERAFGCAACGHQWSLPFGVARPAECPSCSSQNIHRMSPGGGFGGGRRGGGRCRGFRTGLQKREGSGDRCCQTGGQGNGQGRMRRNQQEGGEA
>NZ_CP017305.1|WP_157098344.1|1036429_1037398_+|bifunctional-methionine-sulfoxide-reductase-B/A-protein
MSFRIVSIILVFLLASCGARPVDTAAPRAETAVKKEGSMTYKELTPEEKWVIIDKGTERPFSGQYYLNKEKGVYQCKQCGAALFRSDAKFDSGTGWPSFDDAIPGAVRQETDRDGLRIEILCANCGGHLGHVFYNEGFTSKNARYCVNSISLSFDPADKPATTTEKAVFAGGCFWGVEYHFKKTKGVLSTTVGYTGGKTAHPTYEQVCTGRTGHAEAIEVEFDPSVVSYEELAKLFFEIHDPTQVDRQGPDVGEQYRSAVFYQNEQQQKIAEALIGQLKNRGYEVVTTVEKGGEFWPAELYHQDYYEKTGHRPYCHIYQKRF
>NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGVAVQYSVFECFLSDQDYATLRHRLRKLMDSKHPLDSIRYYRLCRSCVEKVDTDGNRPFAVASPFIIA
>NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1
MGWLYNQMALPETIFQAWYKVAANDGRPGWDNKSIDDYSLRLDENLASLSKALLSGSYQPGPLLKLVMLKPDGNERALLIPGVMDRVAQTAAAMVLSPLIEAELGSSTFAYRPGISRQGAAREIERLHREGYQWVLDADIRNFFDSVRHDLLFQRLASLIDDRELLSILHRWLTAEIVDGATPRRRNTIGLPQGCPISPALANLYLDRFDEALEGEGFKLVRFADDFLVLCKTRPKAEAALKLSESVLGDLKLELNSEKTRITTFADGFKYLGYLFIRSLVIPTKMHPEEWYDKLGKFRLRRKSQHLVPPDPDAMSDERAQFELETGEGEPIQLSKADLLQTEFGARLLESLEKEQVSVDDFLDKIARQDEERLREKREALKKLYSPFLNTLYLQEQGSVMRKDGERFSIEKEGTVVSEVIVRHIEQVVVFGNVALTTPVMQYCLQNEIPVTFLSQHGSYFGRLEATMADNAEMQRFQFLRSIDEPFALETARAIVVAKITNSRTMIRRRTSAIRERDGEVYGRIQTHLALMGDLAAKAETCDEIDGLRGFEGKASALYFECYGLLFSKNLPFHTPSFQRVRRPPTDPVNSLLSFGYSMLHNNVFSMVRLCGMNPYIGFLHAERKGNPGLVNDLVEEFRTVIDSLVLYTLNRGLLKENDFYCRKDQPGCFLSNDARKRYIKIFEERMWQESRDGSTGKTLNFRRQMEKQVRMMRDVIAGTRTQYDPYRLKW
>NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein
MAINPIQKKIKAQQAIKKFAETVVGNKNIGWLSVLCLCLFFIASGWFSDGLAEYIDYLLGGLGPAVINYKLLISIFIILLFWFFVVNVVHGDKDKIIVNNDQSLPTKELVLFLSNFRNIASKESSINAGELVSKEYLEQKYAENAFHFDLLLDTTWEMPFRAIQYHVSKLQHVVLVTSSGGKKSSLESDLFVKLAHVLYPNIRIEEHVVDFENLEQIFDLINHVYEKAKQSGLREDDVLVDITGGQKTNTIAAAIATLAIGRQFEYITTGEKIVRSYDVGYFSRDAS
>NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein
MAIQPLILNFSGHPVSPGQQQAIEKHMHWPSSSVVDVRLGNVPEDNNFAAAITKAIERAGLSREEWQTTPIVAVPAGYPAVWSVILAELHGRLGHFPDVARLRPTQPGASEKYEVAEILNLRELRHASRSKR
>NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MARSGQDIIEFGITLLREHLWNVSADVAEAFRLAGVRESELTLAALKSPFGGDMYFKPAQLSVTAMNYPDSEAPPDFSCVEPGEDEHGLTALEKYGSFVATNANESLPVCHLFKTAAAIQDCLLADGDSEKPFLLVSADFSGIQDTVYTISSKGALKTLRARSFMLELLTEHIVYEILHSCQAERQAIIYSGGGGFSLLLPNRAGVVTAIEGYREVLNRWALQEFSGKFFIALDATPCNAASLESEADFTALRQCQSESLDKLKRQKFLKQLDELFTPTMPKQLTTRTECQITRRDDLLPEKMRDREKGTFMSSVPHERRDDDCYTWLSESCFHQFRLGDKLIDAKKVYRYEEKPDKDKIGYLTLKGINDQDVYYSIDKIVQKDADVWQINSWESTSPTVLYAQYVRKHGELSDFAKEAERESIESVEGRTPKNDDTATFEGLASSSCGADLIGALRMDVDDMGKMFSKIASLPELSVKSRMLNLFFKVYLNEICAGNLGKEEKPTDIVGKNYQEKNPDGTNKGRNVSVVYVGGDDLFILGAWDETAELAFDIQRCFACFTGGSFDSEKKGCGISGGLTLHQPKFPLYQMAQKSGEAEHVAKNDKDTIYGDIEKNRIALFYDDSKYQRRLKMKTPERYRYMLSMTWNLSGDFLIPLMKTYCECGSLKSQDGRLVLEIDKFSYQTIEKWFAVIEKYQESYMLYLPTMARVMKQVEEGKNMNADLFKKLFSYLYTNEESKKNWISHLHIALNWLSFLRRTK
>NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2
MCCCYCNGNDKKKKTVTPNQLRRFYTYIKSIDLANRQTEESVVNFKDKYKLKFILPKIAGSSERESLEDLYEVLNACIKDNKINSVKDFRIFMEFFEAILDYHSTFKSQKQDN
>NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MSDVERMIKLLGYIKITGEIEALTGLHIGGTADSIDKGGIDNPVIKNPVTNEPYIPGSSLRGRIRSLLEKKTAQILSPMTNNKEIWMEIYKSDDDKYKGNKAQSTIDAMNSAVCRIFGNSASYENVPSVLIVRDALYTDKTRDQYMQGGKGGLPITEAKMEIAVDRITAHALPRTIERVPAGAKFLFEIVYKIQSTSFISMIDENGIVKKINKYIADDKVIKKDIENLLWALKQIEEHDGLGGNTSRGHGQVKFSVSPLNCEVFESEYKPKIEDIVNEINNK
>NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MKTYIVHLYFKNALRVGAANASIDIEATQDFIHSDTLWAAIANHWAILGNVNGISFDEFLSGFGSKEGEPKSDPLFLLSSAFPLTENGIKYWLPKPLSVPMAFSKSNTNDPEHQRETYGKKVKQEKFIPLNVFKDWINFEKNASDVGSLERNGISGGQIRPHATLDRISMQAQLFHSGITYFDKFEERVGLYFLVRCNENTKTSLEKIFEVIYNAGAIGGDRSIGLGALAEKPFFIEATAFDDLFSTENSNAHCLLSLSCPNNDEIPKDQDVIAYNTILRKGWTGSLSIGLQRKRQTIYMFSEGSVFRKPIKGSLVDITPDRSITPEWNGMHNVYRYGYALSVPVKIDLND
>NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein
MISKIIELETLTPLFIKGKEEKYGEGFIRIGEELFSVDNDKLCEFIYNNTYDIVGNKTIGKPDYVEFYSDFLLKEQNNEKLSCYNKFAREFGFDEKNDYRKIPERYKEKSIQYFLLSTRLLQGNNVDKKRVMIEHKIAKGITRLEQSNRSGNRFIQNGNNRRYIPGSSIKGAIRNAVLWKILSEYSKKVWLQSFVKYHLSVVDVLSKVSDLIDQREFHQAQILINQNAVLSQAHLINGNRIDKEKLSELKKKYAEFFSDKQDTEQQTMKSISFTEFTPSILISDSFVDDYNKYLDSYNKRWNDANDTLRDFFRLVKVSDANFVQDCNLKAENGEGRLQRYIWYPSKKPNLPKKI
>NZ_CP017305.1|WP_157098345.1|1057110_1057596_+|hypothetical-protein
MSKTQFLHLKNPDKVRVRDMIHPNGSSIAPKSRCLIVEGQNATEPLGWCKLRVLGDAKDMPRPSIDTATIKTELITKQNMQNAKGNYINSGKPLTEREVQKSNATAKAILKQAEKKNTNATHIKYKVGQTVYATVEECVPLTSLKVIIGDQVLNIKALRRI

Crispr_ID: NZ_CP017305_2

• CRISPR_ID: NZ_CP017305_2
• CRISPR_location: 1048730-1049136
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: cas1,cas2,csx1,csx15,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7

Consensus repeat of NZ_CP017305_2

Consensus_repeat	Method
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	PILER-CR
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CRISPRCasFinder
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CRT

spacers of NZ_CP017305_2

>2.1|1048765|42|NZ_CP017305|PILER-CR,CRISPRCasFinder,CRT
CTACCACAACTGACATGTTTTTAAAAATAGAGGGTTTAAAAA
>2.2|1048842|40|NZ_CP017305|PILER-CR,CRISPRCasFinder,CRT
TGAAAATAATTGTCCATGCCCCTTTTGGGATACGACGTGT
>2.3|1048917|36|NZ_CP017305|PILER-CR,CRISPRCasFinder,CRT
GAACGAAAATACATTATTTACTTTATACAAAGAACT
>2.4|1048988|37|NZ_CP017305|PILER-CR,CRISPRCasFinder,CRT
TCATGAGATGAGCCAGAAAAGGACGTTCTAACAAATG
>2.5|1049060|42|NZ_CP017305|CRISPRCasFinder,CRT
ACACGAATGTCCGTTGTTGCTTCTCAAAACATCAAAATACCT

CRISPR arrays and Neighbor proteins around NZ_CP017305_2

CRISPR arrays

The CRISPR arrays of NZ_CP017305_2

>merge|NZ_CP017305|2|1048730-1049136|PILER-CR,CRISPRCasFinder,CRT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAACCTACCACAACTGACATGTTTTTAAAAATAGAGGGTTTAAAAACTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTGAAAATAATTGTCCATGCCCCTTTTGGGATACGACGTGTCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACGAACGAAAATACATTATTTACTTTATACAAAGAACTCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACTCATGAGATGAGCCAGAAAAGGACGTTCTAACAAATGCTTTATAGCTTATTGCACTCGCAGAGGATTGAAACACACGAATGTCCGTTGTTGCTTCTCAAAACATCAAAATACCTCTTTATAGCTTATTGCGCTCGCAGAGGATTGAGTA

>NZ_CP017305|2|3|1048730-1049059|PILER-CR
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CTACCACAACTGACATGTTTTTAAAAATAGAGGGTTTAAAAA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TGAAAATAATTGTCCATGCCCCTTTTGGGATACGACGTGT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GAACGAAAATACATTATTTACTTTATACAAAGAACT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TCATGAGATGAGCCAGAAAAGGACGTTCTAACAAATG
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC

>NZ_CP017305|2|2|1048730-1049136|CRISPRCasFinder
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CTACCACAACTGACATGTTTTTAAAAATAGAGGGTTTAAAAA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TGAAAATAATTGTCCATGCCCCTTTTGGGATACGACGTGT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GAACGAAAATACATTATTTACTTTATACAAAGAACT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TCATGAGATGAGCCAGAAAAGGACGTTCTAACAAATG
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	ACACGAATGTCCGTTGTTGCTTCTCAAAACATCAAAATACCT
CTTTATAGCTTATTGCGCTCGCAGAGGATTGAGTA

>NZ_CP017305|2|2|1048730-1049136|CRT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	CTACCACAACTGACATGTTTTTAAAAATAGAGGGTTTAAAAA
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TGAAAATAATTGTCCATGCCCCTTTTGGGATACGACGTGT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	GAACGAAAATACATTATTTACTTTATACAAAGAACT
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	TCATGAGATGAGCCAGAAAAGGACGTTCTAACAAATG
CTTTATAGCTTATTGCACTCGCAGAGGATTGAAAC	ACACGAATGTCCGTTGTTGCTTCTCAAAACATCAAAATACCT
CTTTATAGCTTATTGCGCTCGCAGAGGATTGAGTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017305.1|WP_069809197.1|1041861_1042416_-|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl|CDD|129813
NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl|CDD|367635
NZ_CP017305.1|WP_069808623.1|1057665_1058892_+|ISL3-family-transposase	unknown	unknown	gnl|CDD|376574
NZ_CP017305.1|WP_069809195.1|1039681_1040041_-|GTPase	unknown	unknown	unknown
NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein	csx1	pfam09670_csx1_CAS-III	gnl|CDD|378236
NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl|CDD|187811
NZ_CP017305.1|WP_069809196.1|1040315_1041560_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809198.1|1042412_1043066_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997
NZ_CP017305.1|WP_069809194.1|1038655_1039681_+|zinc-dependent-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|176258
NZ_CP017305.1|WP_069809193.1|1038160_1038529_+|dinitrogenase-iron-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238431
NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NZ_CP017305.1|WP_169817615.1|1059057_1060443_+|hypothetical-protein	csx1	cd09747_csx1_CAS-III	gnl|CDD|187878
NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|273866
NZ_CP017305.1|WP_069809200.1|1043494_1044493_-|chlorophyll-synthase-ChlG	unknown	unknown	gnl|CDD|236052
NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP017305.1|WP_069809199.1|1043078_1043498_-|YjbQ-family-protein	unknown	unknown	gnl|CDD|223509
NZ_CP017305.1|WP_157098345.1|1057110_1057596_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	gnl|CDD|187735
NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl|CDD|273863

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	2.1e-18	61.6	1.0
NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	7.7e-60	197.0	0.4
NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	5.9e-35	115.6	0.0
NZ_CP017305.1|WP_169817615.1|1059057_1060443_+|hypothetical-protein	csx1	cd09747_csx1_CAS-III	6.8e-24	79.1	5.2
NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.5e-87	288.3	0.0
NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein	csx1	pfam09670_csx1_CAS-III	2.5e-11	37.8	0.0
NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	9.3e-28	91.0	0.3
NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	2.3e-89	295.3	0.1
NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	5.9e-36	117.0	0.0
NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	2.7e-12	41.3	14.9

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017305.1|WP_069809197.1|1041861_1042416_-|TIGR00730-family-Rossman-fold-protein	gnl|CDD|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	6.80562e-56
NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	3.15696e-20
NZ_CP017305.1|WP_069808623.1|1057665_1058892_+|ISL3-family-transposase	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	4.31948e-94
NZ_CP017305.1|WP_069809200.1|1043494_1044493_-|chlorophyll-synthase-ChlG	gnl|CDD|236052	PRK07566, PRK07566, chlorophyll synthase ChlG.	7.7271e-156
NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein	gnl|CDD|378236	pfam09670, Cas_Cas02710, CRISPR-associated protein (Cas_Cas02710). Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	2.6275e-06
NZ_CP017305.1|WP_069809198.1|1042412_1043066_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	8.92537e-32
NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	6.82271e-92
NZ_CP017305.1|WP_069809194.1|1038655_1039681_+|zinc-dependent-alcohol-dehydrogenase-family-protein	gnl|CDD|176258	cd08298, CAD2, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.94244e-171
NZ_CP017305.1|WP_069809193.1|1038160_1038529_+|dinitrogenase-iron-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238431	cd00851, MTH1175, This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).	6.0794e-23
NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.06917e-62
NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	1.88041e-33
NZ_CP017305.1|WP_169817615.1|1059057_1060443_+|hypothetical-protein	gnl|CDD|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	4.22693e-19
NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.38067e-104
NZ_CP017305.1|WP_069809199.1|1043078_1043498_-|YjbQ-family-protein	gnl|CDD|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	1.21775e-48
NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.56749e-30
NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein	gnl|CDD|187735	cd09766, Csx15_I-U, CRISPR/Cas system-associated protein Csx15. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein loosely associated with CRISPR/Cas systems; some are fused to AAA ATPase domain, also known as TTE2665 family.	5.27135e-37
NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein	gnl|CDD|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	0.000102351

Protein sequences

>NZ_CP017305.1|WP_069809202.1|1046283_1048479_+|CRISPR-associated-endonuclease-Cas1
MGWLYNQMALPETIFQAWYKVAANDGRPGWDNKSIDDYSLRLDENLASLSKALLSGSYQPGPLLKLVMLKPDGNERALLIPGVMDRVAQTAAAMVLSPLIEAELGSSTFAYRPGISRQGAAREIERLHREGYQWVLDADIRNFFDSVRHDLLFQRLASLIDDRELLSILHRWLTAEIVDGATPRRRNTIGLPQGCPISPALANLYLDRFDEALEGEGFKLVRFADDFLVLCKTRPKAEAALKLSESVLGDLKLELNSEKTRITTFADGFKYLGYLFIRSLVIPTKMHPEEWYDKLGKFRLRRKSQHLVPPDPDAMSDERAQFELETGEGEPIQLSKADLLQTEFGARLLESLEKEQVSVDDFLDKIARQDEERLREKREALKKLYSPFLNTLYLQEQGSVMRKDGERFSIEKEGTVVSEVIVRHIEQVVVFGNVALTTPVMQYCLQNEIPVTFLSQHGSYFGRLEATMADNAEMQRFQFLRSIDEPFALETARAIVVAKITNSRTMIRRRTSAIRERDGEVYGRIQTHLALMGDLAAKAETCDEIDGLRGFEGKASALYFECYGLLFSKNLPFHTPSFQRVRRPPTDPVNSLLSFGYSMLHNNVFSMVRLCGMNPYIGFLHAERKGNPGLVNDLVEEFRTVIDSLVLYTLNRGLLKENDFYCRKDQPGCFLSNDARKRYIKIFEERMWQESRDGSTGKTLNFRRQMEKQVRMMRDVIAGTRTQYDPYRLKW
>NZ_CP017305.1|WP_069809201.1|1045813_1046098_+|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGVAVQYSVFECFLSDQDYATLRHRLRKLMDSKHPLDSIRYYRLCRSCVEKVDTDGNRPFAVASPFIIA
>NZ_CP017305.1|WP_069809200.1|1043494_1044493_-|chlorophyll-synthase-ChlG
MAGAETQERQESGKAANGEKGALNVRKMVPPQNRSSEPLTSLRLFVRFLKPVTWIPVVWSFVCGAVASGAFGWREVGSVKFLLAVLLTGPLATGTCQMLNDYFDRDLDEINEPNRPIPGGAISLRSATMLIALWSVLSVLVGWLVHPLIALYVVIGIINAHLYSANPIKLKKRLWAGNIIVAVSYLIIPWVAGEIAYRPDFSLQAITPSLIVAALYTIASTGTMTINDFKSIEGDRQVGIHTLPAVFGERKAALIAAVMIDLGQLMAAGYMFMIGEPTYGWVTALLVVPQFLLQFSLVRSPRTWDVRYNAIAQNFLVAGMMVCAFAIKSIEP
>NZ_CP017305.1|WP_069809199.1|1043078_1043498_-|YjbQ-family-protein
MTCGDTISLESRGFSEIHDITPEVRRIVAKSGVRSGIVTISAIGSTASVTTMEFEPALVEDFREKLQQLFPSTERSRHSETWGDDNGFSHMRASFMGPAVTLPVSGGEPVLGTWQQIVFIDHDNRPRSREIFMQLVGEP
>NZ_CP017305.1|WP_069809198.1|1042412_1043066_-|glycosyltransferase-family-2-protein
MQTPHFDLRPAISVILPTFDRAPLLAHAIESVVAQSFAEWELIVVDDGSSDDTFAVVDAFLRQHGNIRYMKHRNRKAALSRNAGIQASFGRYVTFLDSDDLYLPEHLESRFRMLEAMPETTLLSGGFVCEGDPWVRDRNDPGQWIHVRECIAGATMFGRRELFMELGGFQALDYAEDTDLWERASQRFRVLKIDQPESYIYRRSPDSITRTYKQTPS
>NZ_CP017305.1|WP_069809197.1|1041861_1042416_-|TIGR00730-family-Rossman-fold-protein
MIRSVTVYCSSSNRAPDPYFNEAEALGRGLAERKIGMVFGGGHVGLMGCAADAVMRCGGQVRGVIPRFLEEREVAHYGLTELRVVETMHERKMLLTGWADAFVILPGGFGTLDEFLEILTWKHLGHHEKPIILLNVDGFWDQLLQFFERIAKEKMVGESYRAFYDVCDSAEEALALIDRHNASV
>NZ_CP017305.1|WP_069809196.1|1040315_1041560_+|hypothetical-protein
MKPIRIDDYCFDRIHLWLQYDACVPQFIEMVVEVFYPANRKANGLVMFDHGFLIGNDLLWYPKKIAGMLLDDNPLFGINPSDYYNYSSALVEKNWAMAFVSASHAQVDWMPWTDIGGNPRVGQEAYAAASYLIKYGMTNFFWLVEAEGHNSRSFDAELASKAKFLISNNVIFAGHSVGGAHAQAAACGFDTLRQIGANQCRPFNPVIYNREFLPAFSMPMASWKEEHRANPVGLLMLSPVDQSVPLFIPGMSDYRAALASRPMPMAMITGQCDCACLDMSQPPAWSDNGTESQFSQLTGGGKGSWVVASQVERGSHCGYLTDKSPLCSVADMPSECKRCPEGTAYKPMGAEAVFTSEMFRKFIGIYPDGGGFQGGFSDWIQSDFITWLNQKSPCCDLNLMQMPGGGYIDNVPPV
>NZ_CP017305.1|WP_069809195.1|1039681_1040041_-|GTPase
MTTSLIFIYSTDSGTASALLDTGHKALSPSTYHCSLCELTQDTLGEKVRWREFRTSIGLPMEFFHRDEFERKYDLAFDYPVILRKNDKIEILLNKERIDKISNLDDLIDTIRQEMAKTA
>NZ_CP017305.1|WP_069809194.1|1038655_1039681_+|zinc-dependent-alcohol-dehydrogenase-family-protein
MNAMLLERVADLSHETQPLARRSLPVPEPGAGEILLRVGACGVCHTELDEIEGRTPPPRFPVIPGHQVVGSMVACGAGVTGIETGSRRGVAWIYSSCGHCDLCLSGHENLCADFRATGRDTDGGYAEYMVAPAAFTYPIPDLFTDAEAAPLLCGGAIGYRSLMLAGLRDGQILGLTGFGASGHQVLKLARYLYPASPVFVFARSEKDRDLARSLGADWAGDTTDAPPELCASIIDTTPAWLPVLAALERLRPGGRLVINAIRKENRDRELLAGISYERHLWMEKEIKSVANITRADVSTFLDIAARMELRPEVRCYPLGEANRVLLDLRHGRVTGAAVLVP
>NZ_CP017305.1|WP_069809193.1|1038160_1038529_+|dinitrogenase-iron-molybdenum-cofactor-biosynthesis-protein
MKIIIPLDEYSGPGSLVCDHFGSAPFFATVDMVGGEVKIIDNNNMHHDHGQCAPADSFADMGADAIVVKGIGARAAAKMQSLGIAIYMAGSAQRLIDVIEQFGSGILKKLDAQQACQGHGCH
>NZ_CP017305.1|WP_069809203.1|1049152_1050016_+|hypothetical-protein
MAINPIQKKIKAQQAIKKFAETVVGNKNIGWLSVLCLCLFFIASGWFSDGLAEYIDYLLGGLGPAVINYKLLISIFIILLFWFFVVNVVHGDKDKIIVNNDQSLPTKELVLFLSNFRNIASKESSINAGELVSKEYLEQKYAENAFHFDLLLDTTWEMPFRAIQYHVSKLQHVVLVTSSGGKKSSLESDLFVKLAHVLYPNIRIEEHVVDFENLEQIFDLINHVYEKAKQSGLREDDVLVDITGGQKTNTIAAAIATLAIGRQFEYITTGEKIVRSYDVGYFSRDAS
>NZ_CP017305.1|WP_069809204.1|1050245_1050644_+|hypothetical-protein
MAIQPLILNFSGHPVSPGQQQAIEKHMHWPSSSVVDVRLGNVPEDNNFAAAITKAIERAGLSREEWQTTPIVAVPAGYPAVWSVILAELHGRLGHFPDVARLRPTQPGASEKYEVAEILNLRELRHASRSKR
>NZ_CP017305.1|WP_069809205.1|1051008_1053288_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MARSGQDIIEFGITLLREHLWNVSADVAEAFRLAGVRESELTLAALKSPFGGDMYFKPAQLSVTAMNYPDSEAPPDFSCVEPGEDEHGLTALEKYGSFVATNANESLPVCHLFKTAAAIQDCLLADGDSEKPFLLVSADFSGIQDTVYTISSKGALKTLRARSFMLELLTEHIVYEILHSCQAERQAIIYSGGGGFSLLLPNRAGVVTAIEGYREVLNRWALQEFSGKFFIALDATPCNAASLESEADFTALRQCQSESLDKLKRQKFLKQLDELFTPTMPKQLTTRTECQITRRDDLLPEKMRDREKGTFMSSVPHERRDDDCYTWLSESCFHQFRLGDKLIDAKKVYRYEEKPDKDKIGYLTLKGINDQDVYYSIDKIVQKDADVWQINSWESTSPTVLYAQYVRKHGELSDFAKEAERESIESVEGRTPKNDDTATFEGLASSSCGADLIGALRMDVDDMGKMFSKIASLPELSVKSRMLNLFFKVYLNEICAGNLGKEEKPTDIVGKNYQEKNPDGTNKGRNVSVVYVGGDDLFILGAWDETAELAFDIQRCFACFTGGSFDSEKKGCGISGGLTLHQPKFPLYQMAQKSGEAEHVAKNDKDTIYGDIEKNRIALFYDDSKYQRRLKMKTPERYRYMLSMTWNLSGDFLIPLMKTYCECGSLKSQDGRLVLEIDKFSYQTIEKWFAVIEKYQESYMLYLPTMARVMKQVEEGKNMNADLFKKLFSYLYTNEESKKNWISHLHIALNWLSFLRRTK
>NZ_CP017305.1|WP_084022319.1|1053421_1053763_+|type-III-A-CRISPR-associated-protein-Csm2
MCCCYCNGNDKKKKTVTPNQLRRFYTYIKSIDLANRQTEESVVNFKDKYKLKFILPKIAGSSERESLEDLYEVLNACIKDNKINSVKDFRIFMEFFEAILDYHSTFKSQKQDN
>NZ_CP017305.1|WP_069809207.1|1053775_1054624_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MSDVERMIKLLGYIKITGEIEALTGLHIGGTADSIDKGGIDNPVIKNPVTNEPYIPGSSLRGRIRSLLEKKTAQILSPMTNNKEIWMEIYKSDDDKYKGNKAQSTIDAMNSAVCRIFGNSASYENVPSVLIVRDALYTDKTRDQYMQGGKGGLPITEAKMEIAVDRITAHALPRTIERVPAGAKFLFEIVYKIQSTSFISMIDENGIVKKINKYIADDKVIKKDIENLLWALKQIEEHDGLGGNTSRGHGQVKFSVSPLNCEVFESEYKPKIEDIVNEINNK
>NZ_CP017305.1|WP_069809208.1|1054645_1055701_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MKTYIVHLYFKNALRVGAANASIDIEATQDFIHSDTLWAAIANHWAILGNVNGISFDEFLSGFGSKEGEPKSDPLFLLSSAFPLTENGIKYWLPKPLSVPMAFSKSNTNDPEHQRETYGKKVKQEKFIPLNVFKDWINFEKNASDVGSLERNGISGGQIRPHATLDRISMQAQLFHSGITYFDKFEERVGLYFLVRCNENTKTSLEKIFEVIYNAGAIGGDRSIGLGALAEKPFFIEATAFDDLFSTENSNAHCLLSLSCPNNDEIPKDQDVIAYNTILRKGWTGSLSIGLQRKRQTIYMFSEGSVFRKPIKGSLVDITPDRSITPEWNGMHNVYRYGYALSVPVKIDLND
>NZ_CP017305.1|WP_069809209.1|1055705_1056770_+|hypothetical-protein
MISKIIELETLTPLFIKGKEEKYGEGFIRIGEELFSVDNDKLCEFIYNNTYDIVGNKTIGKPDYVEFYSDFLLKEQNNEKLSCYNKFAREFGFDEKNDYRKIPERYKEKSIQYFLLSTRLLQGNNVDKKRVMIEHKIAKGITRLEQSNRSGNRFIQNGNNRRYIPGSSIKGAIRNAVLWKILSEYSKKVWLQSFVKYHLSVVDVLSKVSDLIDQREFHQAQILINQNAVLSQAHLINGNRIDKEKLSELKKKYAEFFSDKQDTEQQTMKSISFTEFTPSILISDSFVDDYNKYLDSYNKRWNDANDTLRDFFRLVKVSDANFVQDCNLKAENGEGRLQRYIWYPSKKPNLPKKI
>NZ_CP017305.1|WP_157098345.1|1057110_1057596_+|hypothetical-protein
MSKTQFLHLKNPDKVRVRDMIHPNGSSIAPKSRCLIVEGQNATEPLGWCKLRVLGDAKDMPRPSIDTATIKTELITKQNMQNAKGNYINSGKPLTEREVQKSNATAKAILKQAEKKNTNATHIKYKVGQTVYATVEECVPLTSLKVIIGDQVLNIKALRRI
>NZ_CP017305.1|WP_069808623.1|1057665_1058892_+|ISL3-family-transposase
MPSLITHYQQLLGLPETWKVSDVRLSTSGPRIEIHLEYIGPKVECPECGKAGRIYDLAPEQRWRHLDTMEYETHLIARVPRCECKEHRIKTIQVPWATRYSRYTLKFEALAVELLQECSSIQSASRLLRLNWHATNEIMNRAVKRGLSRRNKEAIAHLGLDEKSFRAGHQYVTILNDLKGGRVLEVVQSRTTDGAEALLLSFEASQRQGVKSISMDMWKPFAIAAKKHLPQADIVHDRFHISKYLNEAVDTVRRQESRQLHHAGDRTLIGSKFTWLRNPENMTESQRTSFDQLMACELKTGKAWSMKNMFREFWRLGCRESASFFFDYWSERVDQLALKPMIKVKELLKRHLDNILNYFEHEMTNAVSEGLNSKIQLYKASARGFHSFHSYRIRILFYCGKLNMAITG
>NZ_CP017305.1|WP_169817615.1|1059057_1060443_+|hypothetical-protein
MNKRKEWLDKSIADSLDVWSKDADELQHFTGTLKYFGFKQCGISFEIDASNKVPYFQHSLDLFKIVSQKQIAKEDIGLPFLEKFPEYDALITIVGFSPEPLMHTILALAPKKVYPVATEESARDFYKVSLNPITKKPDGKIGYFEAIIERYKEPYQTIIVEDIKKNVASIGSMDTFKRVREIIHAVRQDDKNAKIAIDITGGKKSADVSAFLTASIERNIDIYYVDFEDHNGVKACCGTEFLNKLDNPYDIYNIESVSQAIKLFKQYNYSAASEIFKQTHSKLTDDIVKNYEMVSEKKRIKNMQEAVECYLYLDCFDYSKIDINILPEVQRDLLRDDKYCGTLNYLLNSERRYKQAYYNDAVIRLLQVVEFLLVINSESVYQAIERCIRDDKLKSGLHKLRKARNDFAHNNKVVEESVYTDGIICVKQLVCEKFLKTTNEIDADLKKYTLSTEFNADGTLK

Crispr_ID: NZ_CP017305_3

• CRISPR_ID: NZ_CP017305_3
• CRISPR_location: 1437016-1437113
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP017305_3

Consensus_repeat	Method
ATTCAGGAGGGTTTTAACCCGAC	CRISPRCasFinder

spacers of NZ_CP017305_3

>3.1|1437039|52|NZ_CP017305|CRISPRCasFinder
AGTTATCGGGAAAATCAATCTTCCCTCCTCTTCTGTTGCCCTGGCGTCTTAC

CRISPR arrays and Neighbor proteins around NZ_CP017305_3

CRISPR arrays

The CRISPR arrays of NZ_CP017305_3

>merge|NZ_CP017305|3|1437016-1437113|CRISPRCasFinder
ATTCAGGAGGGTTTTAACCCGACAGTTATCGGGAAAATCAATCTTCCCTCCTCTTCTGTTGCCCTGGCGTCTTACATTCAGGAGGGTTTCAACCCGAC

>NZ_CP017305|3|3|1437016-1437113|CRISPRCasFinder
ATTCAGGAGGGTTTTAACCCGAC	AGTTATCGGGAAAATCAATCTTCCCTCCTCTTCTGTTGCCCTGGCGTCTTAC
ATTCAGGAGGGTTTCAACCCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017305.1|WP_069809695.1|1431267_1432197_-|sodium:calcium-antiporter	unknown	unknown	gnl|CDD|273039
NZ_CP017305.1|WP_069809702.1|1435195_1435933_+|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl|CDD|376413
NZ_CP017305.1|WP_069809712.1|1444276_1444456_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809708.1|1442436_1443243_-|thioredoxin	unknown	unknown	gnl|CDD|225660
NZ_CP017305.1|WP_169817652.1|1437887_1438229_-|hypothetical-protein	unknown	unknown	gnl|CDD|379487
NZ_CP017305.1|WP_069809691.1|1429549_1430257_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl|CDD|181800
NZ_CP017305.1|WP_069809690.1|1428873_1429542_-|VTT-domain-containing-protein	unknown	unknown	gnl|CDD|223659
NZ_CP017305.1|WP_069809688.1|1427844_1428756_-|transketolase	unknown	unknown	gnl|CDD|238970
NZ_CP017305.1|WP_157098368.1|1439144_1440002_-|DUF4292-domain-containing-protein	unknown	unknown	gnl|CDD|372917
NZ_CP017305.1|WP_069809704.1|1437260_1437884_-|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|173193
NZ_CP017305.1|WP_157098369.1|1443603_1444233_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809696.1|1432896_1433631_-|PASTA-domain-containing-protein	unknown	unknown	gnl|CDD|225372
NZ_CP017305.1|WP_069809713.1|1444658_1445132_+|DUF2141-domain-containing-protein	unknown	unknown	gnl|CDD|378303
NZ_CP017305.1|WP_069809698.1|1433674_1434649_-|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|173833
NZ_CP017305.1|WP_069809703.1|1435929_1436943_+|esterase	unknown	unknown	gnl|CDD|366286
NZ_CP017305.1|WP_069809707.1|1441702_1442278_-|5'-nucleotidase	unknown	unknown	gnl|CDD|284381
NZ_CP017305.1|WP_069809700.1|1434738_1434939_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809706.1|1440163_1441348_+|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl|CDD|224017
NZ_CP017305.1|WP_069809693.1|1430330_1430729_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809705.1|1438355_1438958_+|superoxide-dismutase	unknown	unknown	gnl|CDD|223678

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017305.1|WP_069809695.1|1431267_1432197_-|sodium:calcium-antiporter	gnl|CDD|273039	TIGR00367, Uncharacterized_membrane_protein_MJ0091, K+-dependent Na+/Ca+ exchanger related-protein. This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General].	2.27938e-52
NZ_CP017305.1|WP_069809705.1|1438355_1438958_+|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	4.34784e-98
NZ_CP017305.1|WP_069809708.1|1442436_1443243_-|thioredoxin	gnl|CDD|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	9.54783e-50
NZ_CP017305.1|WP_069809702.1|1435195_1435933_+|twin-arginine-translocase-subunit-TatC	gnl|CDD|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	1.13946e-61
NZ_CP017305.1|WP_069809691.1|1429549_1430257_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl|CDD|181800	PRK09362, PRK09362, phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed.	1.55777e-144
NZ_CP017305.1|WP_069809690.1|1428873_1429542_-|VTT-domain-containing-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.91668e-24
NZ_CP017305.1|WP_069809688.1|1427844_1428756_-|transketolase	gnl|CDD|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	4.01485e-125
NZ_CP017305.1|WP_157098368.1|1439144_1440002_-|DUF4292-domain-containing-protein	gnl|CDD|372917	pfam14125, DUF4292, Domain of unknown function (DUF4292). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 243 and 287 amino acids in length.	1.81923e-52
NZ_CP017305.1|WP_069809696.1|1432896_1433631_-|PASTA-domain-containing-protein	gnl|CDD|225372	COG2815, COG2815, Uncharacterized protein conserved in bacteria [Function unknown].	7.80156e-32
NZ_CP017305.1|WP_069809713.1|1444658_1445132_+|DUF2141-domain-containing-protein	gnl|CDD|378303	pfam09912, DUF2141, Uncharacterized protein conserved in bacteria (DUF2141). This domain, found in various hypothetical prokaryotic proteins, has no known function.	7.45567e-46
NZ_CP017305.1|WP_069809698.1|1433674_1434649_-|polyprenyl-synthetase-family-protein	gnl|CDD|173833	cd00685, Trans_IPPS_HT, Trans-Isoprenyl Diphosphate Synthases, head-to-tail. These trans-Isoprenyl Diphosphate Synthases (Trans_IPPS) catalyze head-to-tail (HT) (1'-4) condensation reactions. This CD includes all-trans (E)-isoprenyl diphosphate synthases which synthesize various chain length (C10, C15, C20, C25, C30, C35, C40, C45, and C50) linear isoprenyl diphosphates from precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). They catalyze the successive 1'-4 condensation of the 5-carbon IPP to allylic substrates geranyl-, farnesyl-, or geranylgeranyl-diphosphate. Isoprenoid chain elongation reactions proceed via electrophilic alkylations in which a new carbon-carbon single bond is generated through interaction between a highly reactive electron-deficient allylic carbocation and an electron-rich carbon-carbon double bond. The catalytic site consists of a large central cavity formed by mostly antiparallel alpha helices with two aspartate-rich regions (DDXX(XX)D) located on opposite walls. These residues mediate binding of prenyl phosphates via bridging Mg2+ ions, inducing proposed conformational changes that close the active site to solvent, protecting and stabilizing reactive carbocation intermediates. Farnesyl diphosphate synthases produce the precursors of steroids, cholesterol, sesquiterpenes, farnsylated proteins, heme, and vitamin K12; and geranylgeranyl diphosphate and longer chain synthases produce the precursors of carotenoids, retinoids, diterpenes, geranylgeranylated chlorophylls, ubiquinone, and archaeal ether linked lipids. Isoprenyl diphosphate synthases are widely distributed among archaea, bacteria, and eukareya.	3.25075e-92
NZ_CP017305.1|WP_069809703.1|1435929_1436943_+|esterase	gnl|CDD|366286	pfam00756, Esterase, Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.	3.30692e-20
NZ_CP017305.1|WP_069809707.1|1441702_1442278_-|5'-nucleotidase	gnl|CDD|284381	pfam06941, NT5C, 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). This family consists of several 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C (NT5C) proteins. 5'(3')-Deoxyribonucleotidase is a ubiquitous enzyme in mammalian cells whose physiological function is not known.	1.67966e-69
NZ_CP017305.1|WP_069809706.1|1440163_1441348_+|class-I-SAM-dependent-rRNA-methyltransferase	gnl|CDD|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	1.28101e-122
NZ_CP017305.1|WP_069809704.1|1437260_1437884_-|dephospho-CoA-kinase	gnl|CDD|173193	PRK14731, coaE, dephospho-CoA kinase; Provisional.	4.01759e-122
NZ_CP017305.1|WP_169817652.1|1437887_1438229_-|hypothetical-protein	gnl|CDD|379487	pfam14129, DUF4296, Domain of unknown function (DUF4296). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is approximately 90 amino acids in length.	0.000207887

Protein sequences

>NZ_CP017305.1|WP_069809703.1|1435929_1436943_+|esterase
MRPELVFEAVPGLTLQGNPLGDPAERHVPVYLPPSYHASNTKRFPVIWLLAGFASTGMSFLNFGFGRPTVPEMLDSLIRRGEMPETIIVMPDCMTRYGGSQYVDSAATGQYESYLTGELIPHIDRQFRTLPSARHRAVAGKSSGGFGALRLGMRHPELFSAVGCHSGDMDFELCYRPNFPVAARILEKYKGDIAAFFTRWESLDKKPRSEFALLDMMAMAACYSPDPSKPAPGNMRLPFEPRACQLVPEVWEHWKRFDPLTMLEASTCQDALGSLRQLFLDCGSQDEYNLQFGHRRFSARAAELGIAHRYEEFPDTHADTSYRYRISLPLLAQAIAG
>NZ_CP017305.1|WP_069809702.1|1435195_1435933_+|twin-arginine-translocase-subunit-TatC
MGFLDHLEELRWRLIRAGIAFLVAAIASAFYSEFLVNEVLIRPLKESGPNIQLQNLVPYGQISLYLQVVVFTAFVLAFPFLVWQIWQFIEPGLHETERAASRFMILFISACFFSGIAFGYFVFMPISLKFFAGFGSDLIANNIAVQDYISFFLGTLLTTGLVFELPFISYVLSKIGLLTPAFMRFYRRHAVITLLVVAALVTPSTDMVTQMVIAVPMLLLYEFSIFISGRVQKNRNKKLMQESAS
>NZ_CP017305.1|WP_069809700.1|1434738_1434939_+|hypothetical-protein
MIEQITIRRAGFMTLKNHLRTRTIFVTMKRIKGSPGARRHALPGILPNFSETLDGPFKAIRPRTST
>NZ_CP017305.1|WP_069809698.1|1433674_1434649_-|polyprenyl-synthetase-family-protein
MDINVVTSSVTEELKQFQARYKTVLHSSNSLVDKVTRYVLRQQGKQIRPTLVILAAKACGGVHDVTYRGAIMVELLHSATLIHDDVVDGAEMRRGIPSINALWKNKISVLIGDYLLSKGLLYSLENKDYRSLHLVSEAVRRMSEGEILQIQKTRSLDITEDDYLSVIADKTGSLIATSCAIGAATATDSEEEIASLKSYGEFLGLAFQIRDDLLDYTGDSKKTGKQLGIDIKDRKITLPLIYALRHSDKAEQNKIKSILKSSRKRSVRSGEVIEFVTRKGGLDYAAEVAEGFADKALESIAKFPESDAKRSLQLLVDFVMKRQH
>NZ_CP017305.1|WP_069809696.1|1432896_1433631_-|PASTA-domain-containing-protein
MKKVLILLLSIIVAIVAADKLLLPFLTESGAQTTVPDVRNMNYDTAASQLRKAGLNATKSYNVRYLPDVPPDRVIDQVPEAGAIVKPGRSIALVLNRQDKPSYPMPDLVGRTEAEALRELERLGMVVSSVQTQAVSDSDQDGRVLIQSVPPDVVLKSGNEVSFIVGKLEQEPLGMRRVIVPDVLGMSVDQARGVIVRNGLAVGKIIYEYSDLLVPDTVISQNPSANAMVQFGQPVELTVAAGSN
>NZ_CP017305.1|WP_069809695.1|1431267_1432197_-|sodium:calcium-antiporter
MSDYLLLLAGVASAAIGGEFFVRGAVGIASVLRIAPSIIGVTIAAFATSSPELSVAVNSGLAGKSQLSLGDALGSNIVNISLVLGITLLIAGIPVGSDVLKRDMPVAVLAPLLTGILLIDGIIDRLEGLFMFAIFVAWMATTVKQALKERAPSNSKVAVTKRFLPWVHVFAGLLLLVAAGRLIVLSTTGIAKDFGIDDFIIGATLVAFGTSVPELASTVLAKIKGHDEIGVGTVVGSNIFNSLFIVAVAAIIRPIRVPLTEVVPAILFGILSLLIALPRRGTGWVRRRQGVLLVLMYSIYVTTLFFFSR
>NZ_CP017305.1|WP_069809693.1|1430330_1430729_-|hypothetical-protein
MSKKFDVKEQARDILEENLDMEAVIYLGRISEEMEQIFSSNPTPSFADVQRIVTDYFTTDGRPAAFIEDWLRTAEEHARTRGLDDVERPKAILSDLGVFRFMWFLKERGLTEEQINIVLTGAVQQATGQQGE
>NZ_CP017305.1|WP_069809691.1|1429549_1430257_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MNKITLLHEGKAKKVWQTEDPDLIIQEFKDDATAFNNKKKGSIADKGVTNNAISCRLFTMLGENGIPTHFVSQLNDRDMLCKKLDIVLIEVVTRNVAAGSLVRRYGFAEGTVLPKPIVELYLKNDDLDDPLMNDEHAVALGLGTCEEVAQLKAMAEKINALLVPWFAERHLRLVDFKLEFGRHKGEILLGDEISPDTCRFWDAESGEKLDKDRFRLDLGGVEDAYSEVKRRVLEQ
>NZ_CP017305.1|WP_069809690.1|1428873_1429542_-|VTT-domain-containing-protein
MPEISLMLDTVVAYLQQADPSSVYAVLFLSAYFENVIPPIPGDVPIALAGYLLAFNHITFVSALFWSTTGSVAGFMTVFLLSRFLGLKLYAAGQSEVRHKFAQSVHKLFPPSEMEVVRQKFSGHGYLAVVVNRFLFGSRAVICIVAGMLHLKVSLVLLASLVSSLLWNILLLSSGYLLGSNWDKIGQYAVFYSIPFTALFAGLMVWAVVKYLKKRKQGNAGA
>NZ_CP017305.1|WP_069809688.1|1427844_1428756_-|transketolase
MGKHLKPYPQEKRGKHLQLSTIDELKDMARQVRRDVIRMLAKSNSGHTGGSLGMADIFTALYFRILQHHPHQFRQGADHDMLFLSNGHIAPVWYSVLARSGYFSLDELNYLREVDSYLQGHPTCESGLPGIHIASGSLGQGLSVAVGAALGLRMEGKKGEVFCLMGDGECQEGQIWEAAMSAAHYQLGNLIGIVDYNNQQIDGEVCDVMDVEPFADKWRAFGWDVLTCDGNDIEHFIDTLEYLRKDKNRTKPVVVLATTVMGKGVPFFEGTMPDKSNWHGKAPSKEDEAKALEILGVTIFGDF
>NZ_CP017305.1|WP_069809704.1|1437260_1437884_-|dephospho-CoA-kinase
MERLPLLVGVTGGIGSGKSTVCAMLAGMGCELFEADQIAKELQLEDPQVIRGIEELFGREVYSRDGSGKLQIDRKAIASVVFADPEKLIALNRLIHPKVREAFVREVKRCAREGKRILCKEAAILFEAGADRDLDRIIVVAANDGLRLNRAVKRGLDREEARKRMQAQWPQERLIERAHYVIFNDGTLEELRLQVEQVYRSLLTVAE
>NZ_CP017305.1|WP_169817652.1|1437887_1438229_-|hypothetical-protein
MQKGVALLRRLSFIALFGLLLAGCGSQNREKLNADDLHFAAFYADYLARSGGTSEEAAAPYAELTAAGLDTLFARHKLDQKTFDARLKAYSRDPELWRKVLQEVRRNLDEQKQ
>NZ_CP017305.1|WP_069809705.1|1438355_1438958_+|superoxide-dismutase
MSYQQPALPYADNALEPHISANTIGFHYGKHHATYVKNYNALVEGTPFDAMSLEEVIVQTASDASKVGVFNNGAQAWNHTFYWNGLTPNGGGEPTGEIAAKIAEDFGSVDKFKEELKNAAATQFGSGWAWLVLDNGTLKVTKTGNAQNPITSGQTPLLCIDVWEHAYYLDYQNRRPDHVAAVIENLINWDFVNANYAAAK
>NZ_CP017305.1|WP_157098368.1|1439144_1440002_-|DUF4292-domain-containing-protein
MKSVMKWVGVTAFLVMAGCAQMKTVTREPDLPAERVRLTPELKGLYESVATSAGTLKAMDGYADIYLETPKRRAKAYCTVQLQKSKDARLIVTAGILGWPVADLLIRPDSLFVNDMLNNRMLVGRNNGENLGKIIGVNAGAGRLTETLFGIADVREPASDIASVRHGGGRVSFTVKSANGTKELVVDPLTRELAGLVYFDHWGRKSVEFRFADYRSQADGNGAELRAPREIDMILYRADDPEGSRSLKVVYDERVINPPDFTINFKRPAKTKTVNLDEVERLPWL
>NZ_CP017305.1|WP_069809706.1|1440163_1441348_+|class-I-SAM-dependent-rRNA-methyltransferase
MHALYLKPKEHRRLLGGHLWVFSNELREVPRDIAAGETVQLFTSDGRLLGAGFFNPQSLIAFRLLTRDEEQADRDFFRRKLLEALKLREKIYPETETNAWRLVHGESDGLPGLVIDRFDQAFVLQSFSAGIDLHLPLFAELLRELFDPKAIVVRNESTLRELEGLPLYRETVLGESDDIHQTIRDGGISYRVNILEGQKTGFFLDQRENRRHVRKYSAGADVLDVYTNDGGFALNAMHAGAKSTTMVDISQEALQRAEQNARMNGFGDFSIVAADAFETLGRLRQESRSFDLVILDPPSFTKSRKTVPTALKAYTKLNRLGAHLVRNEGFLATASCSHHVSEEDFLAAVQLGATQAGKHLRLISRAAQPPDHPVLLSMPETSYLKFACFYVTNL
>NZ_CP017305.1|WP_069809707.1|1441702_1442278_-|5'-nucleotidase
MSENSIVIGVDLDGVCADFYGRMRQIAAEWFERPVYELPEEVSWGLSEWGITTQSQYDSLHRFAVTQRELFSSMEVIPGARKYLRLLSDEGFRIRIITHRLFIHYFHAAAVQQTVNWLDSHGIPYWDLCFMKEKSQVGADIYIEDSPGNVEQLRNKGLFTICFGNSTNRHIEAPRANSWQEVYDTVKAFAG
>NZ_CP017305.1|WP_069809708.1|1442436_1443243_-|thioredoxin
MQSSTPFDFQTDVIELSKTIPVLVDFWAQWCGPCRILAPVLKRLADRHAGKWVLVKVNTEEYPEISAQYGIRGIPNVKLFSNGEVIEEFTGALPEHQIEQWLSKALPSPWAEDVERAATEIAAGDNDAAVFLLEGVLANEPENRKAAAMLVKLILFSRPDEALRLAEPLEAEPEYADLSEAVRTLGALLARPSTALPKSESLEAYGLAVESLRKGDLDRALERFIAVLRDDRYYDGDGSRKACIAIFRLLGEEHEITMKHRQAFDRAF
>NZ_CP017305.1|WP_157098369.1|1443603_1444233_+|hypothetical-protein
MSAPMAAFAGTGDLALGVKGGTAGIGGEVTIGVIDNLNFRTGYNYFNYDGSTTESDIDYDYELKLRSLPLLVDLHPFGGGFRVTTGIFLNHNEVTGTAQPTGTTIEIGGTDYPVAGVGTLDAKIDFRKTAPYLGIGWGNAVNSSSPLSLSLDIGVMFQGTPKVSLDATGALASNPAFQESLDQEIEDVKDDIENLKYYPIISLGIAYKF
>NZ_CP017305.1|WP_069809712.1|1444276_1444456_-|hypothetical-protein
MPVNSTLQLAADAIEDARKRLERARVDADDDYEIRQALRHLEDASGYIRKASKELKEQG
>NZ_CP017305.1|WP_069809713.1|1444658_1445132_+|DUF2141-domain-containing-protein
MRSTVPAVLLFSLFATPSITLADSGSAGRIEVLIDNVRSAYGVVGVALFNAKKGFPDNSSMAIEGRSVPAGKSCKVIFENVPYGTYAVSVLHDENGNGKMDKGVFGIPKEGFGVSNNPEIKMGPPSFAESRFDLKSRELSLNIGMKYLRKPETQVRQ

Crispr_ID: NZ_CP017305_4

• CRISPR_ID: NZ_CP017305_4
• CRISPR_location: 1509474-1509574
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP017305_4

Consensus_repeat	Method
CTCATCGGCGGAATGCCCGCCGC	CRISPRCasFinder

spacers of NZ_CP017305_4

>4.1|1509497|55|NZ_CP017305|CRISPRCasFinder
GAGGCAGGGCGACTCCTGCGGCGCGGACGCCATCGCGATGGGCTCGACCACCGTC

CRISPR arrays and Neighbor proteins around NZ_CP017305_4

CRISPR arrays

The CRISPR arrays of NZ_CP017305_4

>merge|NZ_CP017305|4|1509474-1509574|CRISPRCasFinder
CTCATCGGCGGAATGCCCGCCGCGAGGCAGGGCGACTCCTGCGGCGCGGACGCCATCGCGATGGGCTCGACCACCGTCCTCATCGGCGGCATGCCCGCCGC

>NZ_CP017305|4|4|1509474-1509574|CRISPRCasFinder
CTCATCGGCGGAATGCCCGCCGC	GAGGCAGGGCGACTCCTGCGGCGCGGACGCCATCGCGATGGGCTCGACCACCGTC
CTCATCGGCGGCATGCCCGCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017305.1|WP_157098372.1|1503480_1503630_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809816.1|1506891_1507602_+|hypothetical-protein	unknown	unknown	gnl|CDD|224566
NZ_CP017305.1|WP_069809841.1|1531630_1531960_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809812.1|1506249_1506693_+|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NZ_CP017305.1|WP_069809804.1|1501731_1502382_+|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	unknown	unknown	gnl|CDD|236837
NZ_CP017305.1|WP_069809837.1|1527278_1527641_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809814.1|1506697_1506892_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809818.1|1507598_1509365_+|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl|CDD|273730
NZ_CP017305.1|WP_069809806.1|1502857_1503475_+|DUF4255-domain-containing-protein	unknown	unknown	gnl|CDD|379449
NZ_CP017305.1|WP_069809832.1|1525469_1526795_+|ATP-binding-protein	unknown	unknown	gnl|CDD|223540
NZ_CP017305.1|WP_069809800.1|1500416_1501490_-|metallophosphoesterase-family-protein	unknown	unknown	gnl|CDD|277343
NZ_CP017305.1|WP_069809839.1|1527924_1531611_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NZ_CP017305.1|WP_069809822.1|1509751_1510192_+|GPW/gp25-family-protein	unknown	unknown	gnl|CDD|377431
NZ_CP017305.1|WP_069809808.1|1503653_1505741_+|phage-tail-sheath-subtilisin-like-domain-containing-protein	unknown	unknown	gnl|CDD|226028
NZ_CP017305.1|WP_169817623.1|1510216_1513891_+|hypothetical-protein	unknown	unknown	gnl|CDD|274051
NZ_CP017305.1|WP_069809810.1|1505798_1506236_+|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NZ_CP017305.1|WP_069809826.1|1513927_1517302_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809828.1|1517344_1520101_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809830.1|1520329_1522144_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809834.1|1526865_1527288_+|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240038

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017305.1|WP_069809816.1|1506891_1507602_+|hypothetical-protein	gnl|CDD|224566	COG1652, XkdP, Uncharacterized protein containing LysM domain [Function unknown].	0.000502692
NZ_CP017305.1|WP_069809812.1|1506249_1506693_+|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	3.18888e-51
NZ_CP017305.1|WP_069809804.1|1501731_1502382_+|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	gnl|CDD|236837	PRK11081, PRK11081, tRNA guanosine-2'-O-methyltransferase; Provisional.	1.50538e-101
NZ_CP017305.1|WP_069809818.1|1507598_1509365_+|type-VI-secretion-system-tip-protein-VgrG	gnl|CDD|273730	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein. This model represents the Vgr family of proteins, associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region, VGXXXXXX, found in the Vgr of Rhs classes G and E.	3.71896e-85
NZ_CP017305.1|WP_069809806.1|1502857_1503475_+|DUF4255-domain-containing-protein	gnl|CDD|379449	pfam14065, DUF4255, Protein of unknown function (DUF4255). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 320 amino acids in length.	3.11565e-33
NZ_CP017305.1|WP_069809800.1|1500416_1501490_-|metallophosphoesterase-family-protein	gnl|CDD|277343	cd07398, MPP_YbbF-LpxH, Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain. YbbF/LpxH is an Escherichia coli UDP-2,3-diacylglucosamine hydrolase thought to catalyze the fourth step of lipid A biosynthesis, in which a precursor UDP-2,3-diacylglucosamine is hydrolyzed to yield 2,3-diacylglucosamine 1-phosphate and UMP. YbbF belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.61058e-06
NZ_CP017305.1|WP_069809839.1|1527924_1531611_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	4.32262e-19
NZ_CP017305.1|WP_069809822.1|1509751_1510192_+|GPW/gp25-family-protein	gnl|CDD|377431	pfam04965, GPW_gp25, Gene 25-like lysozyme. This family includes the phage protein Gene 25 from T4 which is a structural component of the outer wedge of the baseplate that has acidic lysozyme activity. The family also includes relatives from bacteria that are also presumably lysozymes.	3.05332e-29
NZ_CP017305.1|WP_069809808.1|1503653_1505741_+|phage-tail-sheath-subtilisin-like-domain-containing-protein	gnl|CDD|226028	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only].	8.84772e-52
NZ_CP017305.1|WP_169817623.1|1510216_1513891_+|hypothetical-protein	gnl|CDD|274051	TIGR02243, hypothetical_protein_SCD8A.17c, putative baseplate assembly protein. This family consists of a large, conserved hypothetical protein in phage tail-like regions of at least six bacterial genomes: Gloeobacter violaceus PCC 7421, Geobacter sulfurreducens PCA, Streptomyces coelicolor A3(2), Streptomyces avermitilis MA-4680, Mesorhizobium loti, and Myxococcus xanthus. The C-terminal region is identified by the broader model pfam04865 as related to baseplate protein J from phage P2, but that relationship is not observed directly. [Mobile and extrachromosomal element functions, Prophage functions].	8.43267e-07
NZ_CP017305.1|WP_069809810.1|1505798_1506236_+|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	4.13551e-51
NZ_CP017305.1|WP_069809832.1|1525469_1526795_+|ATP-binding-protein	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	3.34847e-38
NZ_CP017305.1|WP_069809834.1|1526865_1527288_+|NUDIX-domain-containing-protein	gnl|CDD|240038	cd04682, Nudix_Hydrolase_23, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	2.56971e-34

Protein sequences

>NZ_CP017305.1|WP_069809818.1|1507598_1509365_+|type-VI-secretion-system-tip-protein-VgrG
MSPENTIPTPATPDVCTFAVLVDGAEIPGRFQLVALSVSHELNRIPAAELHLLDGQASTGTFAASDDELFIPGKEIEIQLGYRSTNDKVFKGLIVKQSVRIRKNGSFLFVECRGNAVKMTRGVKSRYFVDMKDSDVMEEIIGEHGLTSDVTASTPEAGSVVQYESTDWDFLLCRAEANGMVVAVADDTVTVAPPDTSAATAVTVRFGATVLELDAEMDARVQQSGIKATSWSPADQAMVESEASEPSTTGNGNLSADDLAGVLGGDTGVIRHGGNLSQPELQAWADGRLMKERLSKVRGRVRFQGMAAILPGQVIEVTGIGARFEGKLYVSGVRQTVSGGNWETDVQFGLDPELFPERYNLRPLPASGLLPGVGGLQMGVVTVLEGDPESMGRIKVRLPLISDSDEGVWARLATLDAGDGRGTFFRPEIGDEVVVGFIADDPRHPVVLGMCHSGAKPAPEPASDDNHRKGYVSREKLMLTFDDEKKIIHLETPGGNKLSLSDEKKGILIEDMNGNKITLDDKGITIESASDIVLKATGDLKAEGVNIELAAQSGFKAEGSATAELSGASAEVKGSATAKISGGMVQIN
>NZ_CP017305.1|WP_069809816.1|1506891_1507602_+|hypothetical-protein
MAESGKLEKMLILAFADSKKAESGGKKEADDYVEALINPESYTQSYKLKFSKSGQGQGSSGQQLKYEYSEPGEMSFDFLFDNTGIIDGTPRDSIADDVQKFRKVLTDYKGDAHEPRHFKLVWGENSIFKGRVTSLEITYKLFKPDGTPLRATAKVTFKSSIEEEKRAATEDRQSADLTHIRKVRAGDTLPLMCFRIYGDSKYYLDVAAANGLDNFRSLTPGAEIRFPPIDKTGKLS
>NZ_CP017305.1|WP_069809814.1|1506697_1506892_+|hypothetical-protein
MPVEIRELHIKVTVNESESGDGASAGREAGERSGNSAGGAADREAIVAECVEQVLRIMQNKRER
>NZ_CP017305.1|WP_069809812.1|1506249_1506693_+|phage-tail-protein
MVDYYPPWGFYFRVVFGISKDKNDARFQSVSGLSVEYDFETFREGGENRFEHKLPVRTKYADLVLKRGLLTDSTVIGWLTDAFQNRSFTPTDLSVNLLNEKGEPLQTWNVVHAIPKKWLVSDFNANENSVVIETMELSYRYFTVQKG
>NZ_CP017305.1|WP_069809810.1|1505798_1506236_+|phage-tail-protein
MAQEYPIPRFHFQVDWGGAKLSFTEVTGLVMEREKIEYRHSDSKDFSKIAMPGMVKNSNITLKRGKFENDFDFNAWLEAVANERVENRRDVTIRLLNEKHAPVAAWTAARCFPVKITAPDLKSDANEVAIESIELAHEGLKLMKV
>NZ_CP017305.1|WP_069809808.1|1503653_1505741_+|phage-tail-sheath-subtilisin-like-domain-containing-protein
MATMYKTPGVYIEEIPKFPPSIAPVATAIPAFIGYTEKALKNGESLTSKPTRIESIAEYVELFGEGPSQKIELYLDADNNYISSGKPAGSKARLLYDSLRMFYANGGGNCYIVSIGSYEESLDKQAFLDGLAAVESEDEPTILLFPDAVNLDDSGLHDVQVAALSQCNKLMDRVALCDTVNSGDFGADVQRLRDGIGINNLKYGAAYGPWINTSLPRTFYNRDLTLRRDDKNGDPIALNSLTSDSAIQQMLSDVAEAQKAVDALRDAENAAAGEGKSWTEQLKKLSDAYNALPADADLTTDVQPALQGIYDLLALVVANVKDMADGLPAVVSASPDPSVPETKDFILAKDITQYLGSSALKSSVFDVLAAHYNYLATTGMPGEPEEGSEEEPENVTIKLFSDNPSSATTDLGKAIELLDYANAAAFLAVSKTDVTAKYAAATTAREMADIARNAAAQAASSIIALFRFAESSAAEYEKKFNDALLSSFGTYKSLVSKAIESMNQLPPSGAIAGVYAAVDSNRGVWKAPANVSLNSVVSPAAKISQEQQADYNVDVNAGKSVNIIRSFTGKGVLVWGARTLAGNDNEWRYVNVRRFFNFVEESVKKATEQFVFEPNDANTWVRIQAMIENFLTVLWRQGALQGIKPEHAFYVSLGLGKTMTALDILEGRMIIEIGMAAVRPAEFIILRFSHKMAES
>NZ_CP017305.1|WP_157098372.1|1503480_1503630_+|hypothetical-protein
MTERTERTSSGLFAPLRIAAVCGVGGDFGIVDSEGKPLALSCFGDIHLT
>NZ_CP017305.1|WP_069809806.1|1502857_1503475_+|DUF4255-domain-containing-protein
MISHALTIVVNELNSHLKDIYAMDTEIARPGNPSDGFDMSNNSSSRESVIFSVINIREEKTLKNQPNYLRDETTLKALYENPPVFLNFQILVMAPHANYSNGLLMISRVLRFFQYKNVFTQDNVQPASITSNAPTNDLDCLESFKLIFDLYSPSMEEINHLWGTLGGKQYPFVIYWMRMLDLKFSAPPQEGSLIQEVITDITHKY
>NZ_CP017305.1|WP_069809804.1|1501731_1502382_+|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH
MVSPERFRKIRELLEKRQTDLTLVMDNVNKPHNLAAIIRSCDAVGIHQVHAISYRSSIKTKQHTAAGASRWLKVRLSESVTPVGEKLRKAGAQILVAHYCPEAVDFRAIDYTRPTAIVMGEELKGPSEEALDLADNYIYIPMMGMVESLNVSVAAALILFEAQRQRQAAGLYDTRRFNDADFERLLFEYTYPRLAAVLREQGKPYPTLDENGGFTE
>NZ_CP017305.1|WP_069809800.1|1500416_1501490_-|metallophosphoesterase-family-protein
MSLHQKKHPHLEKLLETARPVRLDSSSKVLILSDLHMGNGGRRDEFRRNAELVRSMLQEYYLPGQYSLVLNGDIEELFKFSVEDITRVWGHIYELFLQFEKNGFFWKTYGNHDSDLFEERDYPLSKHLLESIRFQYEEEVMLLFHGHQASILLWETYPLVSRAVVLFLRYVAKPIGIRNFSTAYNSRRRFAIEKSIYEFSNQAKIVSIIGHTHRPLFESLSKVDHLNYKIEELCRQYSSAPKDERLAIKERIGELKAMLDACFTEGKKIGLRSGRYNNIVIPSVFNSGCAIGKRGVTALEIDGDRIRLVYWFKEKQGRRFVSDRNHEPEQLGNSGFYRIVLNEDHLDYVFSRIRLLA
>NZ_CP017305.1|WP_069809822.1|1509751_1510192_+|GPW/gp25-family-protein
MQYPFLGRGWAFPPVFDRNLPGARMLEDEADIASSLAVLLGTAQGERVMMPWFGCNLDELIYESLDTRIKTLVADKIESAILYHEPRIRLEKVSIEKSDENEGILLISIDYLVKATNSRFNMVYPFYIQEGTDIDMAITVNPLGEN
>NZ_CP017305.1|WP_169817623.1|1510216_1513891_+|hypothetical-protein
MKQANPDRLMRDGTSRKQRFPAALDPSSAPIDGRRPEELIAFARNYSASVRYHDQNNAEIDDWKRFFSEDIAVRVACAAIENVERYRRRIKELLDILKNEGGAASEAQPATVLGWLFSDIGTLARELDRLKEGFDPAVALKATLRNLIASRLAPAFGKLVAAFKGGVKLGHIQPETEADGEIVIFEAAPEPFEAICAAGLSKEWITGEATEWAAYIDSIGADETLYATLPGLDAYGRLARHNLFTSQLDLFLKACARTVADAKAALPELLTGRDDHQPHYALFLAFVQLMELSRTHLNTLTARHLDFYYKEVLKLAPNASEPDKVHLLFELVKNRETARLEAGTLFKGKDEAGRSIEYALDEELVANRAAVEAMRAVRHSLNSDDKPRLYAWPKIDSGDGIGGEITATDGQWHPFLNGTGVTSLAEVGFVIASNCLLLREGNREITLTLEFTGGKVSQTAFCNSFDFYLSTGKKWVQATLDTAKLSNSASKKITISLLFDGAQSAVEPMTGADPGNALPATLPMLKAVLKQESAKSLPLSTLQELRLNAAKSQLDISVGYGGDNQPDGYGLKSLAVSNKFGDLKTDKPFQPFGATPESGDWLVVGSDELFQKKGARFQLRIVWKGLPFWRGDIDFDWVNEFYPKADFAFLKQGAWPEKNELENQRLFSWKNAEVAIPASKTALPALALTETHFDTTRYTLDSRCGFMKLTLDGDFGHKLYPLTLSRYMMRVAAKDTELVDDCMTLWKKERHSLYVWKDGRKEPKNPKNFTSQFVETFSKCLPVEPYTPVIESLTLSYTASTTLSDAALYQLTPFGSKAIAPGEETGLLHRFDNEGEFYLGIGDFTPGQNLTVLFQLAEGSAAPTVSKPEKHVSWSWLRSNEWVDFETSEMSDDTTQLTRSGIIRFAVPATATSGDALLGGEKLHWLRATIREKPEAVCKIIAVATQAARATRVTGGDSAGQLAAESIKKAVTPDASVKKITQPYASFGGRKAEDETAFRTRVSERLRHRNRAITMWDYERLVLEAFPQIYKVKCLNHTRYEPGATGAGIYRELAPGHVTIVTVPNLRNSNAVDPLRPYTSLGDLDLVRTFLEAHTSEFVTLHVQNPAFETIETGFSVRFMPGINEAFYKALLQQELTRFLSPWAFEEGMDIAFGGRIHKSSLIDFVEERSYVDYVTAFRMYHTGSDGKKSDDLDEASASLPLSILVSAEASRHEITPISGELDG
>NZ_CP017305.1|WP_069809826.1|1513927_1517302_+|hypothetical-protein
MAVTTGTIQKEPRREPDQEFTALRRKGIELIERMSSRWWTDYNSHDPGVTMLEALCYAITDLGYRIGWDIADLLQNPPGDGSGDSIQPFFTAREILTVNPLTADDFRRLLIDHEGIGKAWIANSQTDCESAWYADCKHDRLSFMPTGAQTFERNAISPRGIRDVFVQFENDPELGDLNDRKIRHAFAIQPSEGKALEVTAEFRMPAWSTKAWGETSVYVNDGGKLKGSVTGVTLNNIVESERKLSYLADLKILFTPDPVDKDESDSGDDAEVATVITLDLPAVPVRLYGSTSELKSYGDTWSFSDFDSAELARAVAEPFLLKSAAVQRITGEATSLLRARRNLCEEFCRIEPVQTEEVAICAEILVTAEADIEQVFASMVFAIENCFNPPLAFHSLDELLREGMAVEEIFEGPMLKHGFLKQEELDNARLRKSLRTSDIINEIVEIEGVVAVRNLRLTRYDSAGNPASGVADIAPGVDKKKISAEWTLEISENCLPILSIDNSAFLFFKNDLPFVADFAEVRDTLEQLRGEAERLKARHSGSLDLPVPAGRYRDPEQYTPVQYSLPATYGTGPDGVREPATAERRAQVKQLKGYLMVFEQLLANTFSQLAGARHLFSLDPEMQQTMFVQSLNDENLILGVTEILKAELDEAALHGMVETTATMQERRGRFLDHLLARFGEQFSDYALRLTGYDGKKKPAETLIEDKLAFLSALPELSRDRAKGLNTAATALTPEDEAVLKKRISLLAGLAPETAEKIIVVEHLLLRPRFPGDALMEACLDEQPCGACGEADPYSFQLTVVMPGWLAPFDKNIELRRFVENTIRQELPCHILGKICWVDNHDYDAAYREKLTVPLADYLREEGRNAGNARPSVGNAQKGANNLHDAALESFSAWMKSEQYRTTPDDKRQTTLRDLFVAELDPLSNIYSGVSNYDVISPTIYDMMSEHFAEVVEDDRWYIYKRFKDAWDAWLAALPERQRREWKPAGFVSRVQALMTGMIGSWLDPAQTARQALEQFGDLFDRAMRELAAAGDAVDDPKEVVAIILDCALRYPPFNSRSLSADEKEALQRLFIELYAPRLHDSLLLREVVTMHARLTSIYPPATLHDCVDGNDVNPVRLDSTILGA
>NZ_CP017305.1|WP_069809828.1|1517344_1520101_+|hypothetical-protein
MIPENNIYPSFEVNQVLSAAHLNTLHDRLDEQNRLTRATLHGVGIACGLEVSMTKSAGNATISISKGYGVTSEGYAVIIGDAGFRADRCRSLEVKDGYEPLLLDKADGAGDILELLDSDHEHYLDEGTTTIDADDALEMAVVLYVELLETSLKTCTPGSCDDKGKKVTVNLRKLLVPTSYLDALHEEVAGEIDKSDAEGDFFPNLAARLDLADLRMPRFDVPATTLTDAESIIAAYKKILIDPLDDADKSLFKRIGEALDAARTAYAPLLDESEKEFSSALAALEARFTAPENSKDAAFQYYYDFLNDLIQAYDEFRAKAFELTALCNPPSRLFPRHLELGEPEASSGDTPSAEAGIISYRHYFRPSPALGELKARREEVQSLYNRLQAMVASFDPLAPDSSKSADENIRVTPSRPADAPLSQRAIPCYYDPKSARLLDAWDYAKTTAGRSAHNCGCRVEGDESLDWSLDQRGFFRIEGHIGLDWDKALDALQKKIAAYRLPFDVLVLKTETPPGGLPEEELQGYLPEFLKKHPGIEHQSGVMPGGTFVMVCNKAGSTASSPYNAILSRFGSKAIVADFSLPYRIAETVKPADIAVAECEYDWIDTIRHLNNITLRKYRKQATSSAPAAHEAEAGRLASNYVVRIRQYEIQGRNFLGNRSFIDVVVPLAELKQYGHAAIMKRLNEEFPLGVVFDHTAGSGNVLIRAVRGQRFRIELEGVQGNRIRYAYTENGMYRFQNDLWEQIGESGEKSACRLIAGNYDENVYLWLRQHFGQPSKLTTIQRPTAKEVIDWQKLTLARARRYAKAGSLPISALLETIASAIRQIDPNAGIVLVGSWANGSWLSRIEAENLASFGGSKENLDAFRSLNKKVTGRSGYSDIDLMIDSAEAITPEMIRVVSGYAITMFRGKKDAQKGVVL
>NZ_CP017305.1|WP_069809830.1|1520329_1522144_+|hypothetical-protein
MTTVERHTIGKQFLDIRYNGSATGAMALQSAISGLNRHGIAPRIEQILDRHADSASVLKIDRLEVDAGAVPLEEIESRLPAMIAEALDKALADIAMPEAKISGEAIEESPARRLSEAEAAVDALLFFLRHGTLPATWRPQSHESFEAQLHEAWKRPDLARQTAEALASPTARQRLLAQFSRQIPVTLLETLLPDAMPVIEKILDNFRNAGLPEESTGRIERELIDEALALSTRRTNISTEELQVMLVEIAMSLPEIQASVPDDFRSDESLKNPRSQEKSRTSATDSAEGETARVTRDSAPPAHRESDETPLSGQSESDLAHSDNHPPNMSSETAAQDGQSTPSGNQRSDRSVGVTERSPDSFSVSRDANTGNRTTGNSSPEQTNEPWAHGASGDRPATTSQASFSGSGSDSTAKHQDSGHQRTPFRHTAEPVPEHPDERRGLYVENAGLVLLHPFLPQMFEALGIAGDDELLRPGEALRLLHYLATGDETAPEYELALPKILCGLPPASLAGEAGPFTDEEREESAALLSAVIRHWEALKNTSPDGLREAFLKRPGKLTRWHDGGWLLQVESNSFDILLDRLPWGFSMIRLPWMPSMLHVEWRF
>NZ_CP017305.1|WP_069809832.1|1525469_1526795_+|ATP-binding-protein
MNNQDSSLLPAIDWLETIIDARFAQHCKGSGDRGIPRLQLSTTNLRLAEFMRSHEPDAEEFALLMLALAPHLQPDFFGKIIAEYLPDGGDFPEFGGVRGVNHRGLLPTGETAQFVIGGDDLEKRLDVQRLLGPEHWFAKEHILWLEPVPEGEPVMSGRLTLNPEVVEQLTLGTTSKPRFSMEFPAEYIETGMEWSDLVLPAATLRQISEIEHWITHNDTLLGDWGMKKRVKPGYRALFYGPPGTGKTLTATLLGKQTGKEVFRIDLSRIISKYIGETEKNLSRLFDKADSKNWILFFDEADALFGKRTDIRDAHDKYANQETAYLLQRIESHNGLVILASNRRGNLDEAFSRRFQSIIHFPMPKPEERHALWLNTLPERMMTDAEIDWQAIATRYELSGASILNIVHYCAIESLANPAHPLDNKRLEKAIMREFIKEGKVV
>NZ_CP017305.1|WP_069809834.1|1526865_1527288_+|NUDIX-domain-containing-protein
MKRAGASIILKNPRNQVLLFLRDDKPEIPYPNLWDLPGGHVEDAETPKACIMREMLEEIETDVSACHRHAIYDFPDRIEYIFLMDFEAAAETIPLHEGQCLRWFAEKEIPWDNLAFGFEFVLRDYFAGRQRWDDDGEVQD
>NZ_CP017305.1|WP_069809837.1|1527278_1527641_-|hypothetical-protein
MDSSAGRPKPSSIHVEWRENGDFVFSCRYRRAGERDAPEAARRADERHHFPTMTLAMGNVLRKLRREHISFPLFLVSLAFNHRNLLSEIDRLLQALHNHVDQQKGSGEYTCLVTSREDQS
>NZ_CP017305.1|WP_069809839.1|1527924_1531611_-|tetratricopeptide-repeat-protein
MAIQVFIKERSREGEKFTATVQFDALGESEPLTVENPATPEQEQELEWYFEQWLNFPFTDKARAERAAGIIRAYGESLFAQVFRSDPDVYAEYRSAMGRGGVTLQVIGSPEFHALHWEALKDPNQPHPLAVDQPVVRKNHKAVVDPARVAEAPELRVLLVTARPSGRKDVGYRTISRPLIEELETGKLPATIDIVRPGSFRALLQHLEATRNDHGDGYYHMLHLDLHGAVLTYAEYQHISEQAASSSAHLFKGYGCSPVEQYDDERAFLMFEDGESHDGNGGELVSAEDIASQLRLHQIPVVALNACQSGKQVGATETSLGSRLLQSGAQLVIAMGYSVTVSAARLFMTRFYQELLAGREPATAIRSARLELFRDKARKGAYNREIDLEDWMLPVIYQNTPVQFRFSAAAPRAAFAMPRYPKPATAYGFFGRDLDVLEIERRLLKRGNLLLVQGMGGAGKSTLLHHLGWWWQKTRFVEQVFYFGYDLKAYRLPMIIAAIGEQLGLPLTGRMQEDRHEVTRYLKSSRHLLMLDNMESITGERLSIPNTLNDAERQELKGFLQELTGGKTLVLLGSRGNEEWLQPNPLNQHRIYDLPGLDGEASSQLADKILRDIGAPNYPDQPEHRDAFKRLLRLLGGYPLAIEVVLSNLARSTPAEVLQRLEAADIDLDNQSATAGKTDSIIKCIDYSHSNLSEPARQLLLTLAPFKGVVNKRWLEQYSKKLLAQPVLAGLPCEKWEEVLREAEKMGLLKPHENEGLAEFGYLSLQPVFPFFLNTRLNDPAQAERKAAIETAFREHYEGIGDFFGELTDSKEAGQKQAGYALIGVEYENFYTALQIALRQQQSILTVFLNLSNYLDKTQQHQQGLELGRQVMQGLERWPEELIQGQIGYEFVGVLVDEIGTRSMKLQQFQEAEVTYSKALELWDGMTIPSSEQKGTARATILHQLGMVAQEQRKYEEAEGYFKDALAIKIEYNARYEQASTLHQLGRVAQEQRKYAEAERYYKDALAIKIEYNARYEQAGTLHQLGIVAQAQQKYDEAEQYYKEALAIKIEYNARYEQAKTLHQLGNVAYLQRKYAEAERYYKEALVIKIEYNDRYEQAGTLHQLGNVAYLQRKYEEAEGYYKEALGIYVEFNDRYEQASTLHQLGMVAEEQRKYEEAQAYALEAAELFVEFNDQYSLAIVLGTLGRIWRATKDRGIIDKVAVLLNSSASECEQLLDEAAEAEGSKKV
>NZ_CP017305.1|WP_069809841.1|1531630_1531960_-|hypothetical-protein
MDYRLAFDPSLDLAADELAAAWNASEFAEEATASLQPAFAASFPIGEMTLLLLSAAASIPAAVIATFITDYLKRKFPDKKPPAIEVTTIYSLDGELLFIIRKSIERQES

Crispr_ID: NZ_CP017305_5

• CRISPR_ID: NZ_CP017305_5
• CRISPR_location: 1568924-1569013
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP017305_5

Consensus_repeat	Method
GCCGGTCAGCGGCCTCGTCAATCT	CRISPRCasFinder

spacers of NZ_CP017305_5

>5.1|1568948|42|NZ_CP017305|CRISPRCasFinder
GGAGGAGCTGTACTGCTCCGAAACGATGGTGAGCGACCTTTC

CRISPR arrays and Neighbor proteins around NZ_CP017305_5

CRISPR arrays

The CRISPR arrays of NZ_CP017305_5

>merge|NZ_CP017305|5|1568924-1569013|CRISPRCasFinder
GCCGGTCAGCGGCCTCGTCAATCTGGAGGAGCTGTACTGCTCCGAAACGATGGTGAGCGACCTTTCGCCGGTGAGCGGCCTCGTCAATCT

>NZ_CP017305|5|5|1568924-1569013|CRISPRCasFinder
GCCGGTCAGCGGCCTCGTCAATCT	GGAGGAGCTGTACTGCTCCGAAACGATGGTGAGCGACCTTTC
GCCGGTGAGCGGCCTCGTCAATCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017305.1|WP_069809904.1|1575954_1577502_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl|CDD|225098
NZ_CP017305.1|WP_157098378.1|1582012_1582714_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809910.1|1581036_1581933_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809892.1|1559170_1560106_-|thioredoxin-disulfide-reductase	unknown	unknown	gnl|CDD|273540
NZ_CP017305.1|WP_069809896.1|1565540_1567916_-|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl|CDD|224471
NZ_CP017305.1|WP_069809887.1|1556423_1556633_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809908.1|1578756_1580646_-|molecular-chaperone-HtpG	unknown	unknown	gnl|CDD|235366
NZ_CP017305.1|WP_069811489.1|1557405_1557699_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|224583
NZ_CP017305.1|WP_069809906.1|1577605_1578481_-|rubrerythrin-family-protein	unknown	unknown	gnl|CDD|153122
NZ_CP017305.1|WP_069809889.1|1557061_1557409_-|DUF86-domain-containing-protein	unknown	unknown	gnl|CDD|225236
NZ_CP017305.1|WP_069811495.1|1560622_1564171_-|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|235554
NZ_CP017305.1|WP_069809902.1|1571625_1573509_-|biotin-attachment-protein	unknown	unknown	gnl|CDD|227349
NZ_CP017305.1|WP_157098375.1|1571062_1571200_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809894.1|1560193_1560523_-|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_CP017305.1|WP_157098374.1|1569665_1571066_-|DUF262-domain-containing-protein	unknown	unknown	gnl|CDD|377008
NZ_CP017305.1|WP_069811497.1|1564333_1565380_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340832
NZ_CP017305.1|WP_084022348.1|1557733_1558087_-|addiction-module-protein	unknown	unknown	gnl|CDD|378247
NZ_CP017305.1|WP_157098376.1|1571257_1571437_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069809891.1|1558368_1558821_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069811499.1|1573616_1575149_-|fumarate-hydratase	unknown	unknown	gnl|CDD|377546

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017305.1|WP_069809904.1|1575954_1577502_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl|CDD|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	6.50582e-119
NZ_CP017305.1|WP_069809892.1|1559170_1560106_-|thioredoxin-disulfide-reductase	gnl|CDD|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	1.39777e-156
NZ_CP017305.1|WP_069809896.1|1565540_1567916_-|glycoside-hydrolase-family-65-protein	gnl|CDD|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	0
NZ_CP017305.1|WP_069809908.1|1578756_1580646_-|molecular-chaperone-HtpG	gnl|CDD|235366	PRK05218, PRK05218, heat shock protein 90; Provisional.	0
NZ_CP017305.1|WP_069811489.1|1557405_1557699_-|nucleotidyltransferase-family-protein	gnl|CDD|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	8.23115e-32
NZ_CP017305.1|WP_069809906.1|1577605_1578481_-|rubrerythrin-family-protein	gnl|CDD|153122	cd02431, Ferritin_CCC1_C, CCC1-related domain of ferritin. Ferritin_CCC1_like_C: The proteins of this family contain two domains. This is the C-terminal domain that is closely related to the CCC1, a vacuole transmembrane protein functioning as an iron and manganese transporter. The N-terminal domain is similar to ferritin-like diiron-carboxylate proteins, which are involved in a variety of iron ion related functions, such as iron storage and regulation, mono-oxygenation, and reactive radical production. This family may be unique to certain bacteria and archaea. .	1.94368e-57
NZ_CP017305.1|WP_069809889.1|1557061_1557409_-|DUF86-domain-containing-protein	gnl|CDD|225236	COG2361, COG2361, Uncharacterized conserved protein [Function unknown].	2.24615e-37
NZ_CP017305.1|WP_069811495.1|1560622_1564171_-|DNA-polymerase-III-subunit-alpha	gnl|CDD|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NZ_CP017305.1|WP_069809902.1|1571625_1573509_-|biotin-attachment-protein	gnl|CDD|227349	COG5016, COG5016, Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion].	9.8296e-147
NZ_CP017305.1|WP_069809894.1|1560193_1560523_-|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	3.21342e-49
NZ_CP017305.1|WP_157098374.1|1569665_1571066_-|DUF262-domain-containing-protein	gnl|CDD|377008	pfam03235, DUF262, Protein of unknown function DUF262.	7.91471e-09
NZ_CP017305.1|WP_069811497.1|1564333_1565380_-|glycosyltransferase-family-4-protein	gnl|CDD|340832	cd03802, GT4_AviGT4-like, UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.	1.25634e-153
NZ_CP017305.1|WP_084022348.1|1557733_1558087_-|addiction-module-protein	gnl|CDD|378247	pfam09720, Unstab_antitox, Putative addiction module component. This entry defines several short bacterial proteins, typically about 75 amino acids long, which are always found as part of a pair (at least) of small genes. The other protein in the pair always belongs to a family of plasmid stabilisation proteins (IPR007712). It is likely that this protein and its partner comprise some form of addiction module - a pair of genes consisting of a stable toxin and an unstable antitoxin which mediate programmed cell death - although these gene-pairs are usually found on the bacterial main chromosome.	9.70269e-09
NZ_CP017305.1|WP_069811499.1|1573616_1575149_-|fumarate-hydratase	gnl|CDD|377546	pfam05681, Fumerase, Fumarate hydratase (Fumerase). This family consists of several bacterial fumarate hydratase proteins FumA and FumB. Fumarase, or fumarate hydratase (EC 4.2.1.2), is a component of the citric acid cycle. In facultative anaerobes such as Escherichia coli, fumarase also engages in the reductive pathway from oxaloacetate to succinate during anaerobic growth. Three fumarases, FumA, FumB, and FumC, have been reported in E. coli. fumA and fumB genes are homologous and encode products of identical sizes which form thermolabile dimers of Mr 120,000. FumA and FumB are class I enzymes and are members of the iron-dependent hydrolases, which include aconitase and malate hydratase. The active FumA contains a 4Fe-4S centre, and it can be inactivated upon oxidation to give a 3Fe-4S centre.	1.95199e-94

Protein sequences

>NZ_CP017305.1|WP_069809896.1|1565540_1567916_-|glycoside-hydrolase-family-65-protein
MTGSSLSGDGMPVEELDVLFELSPEEWLLRKKGYRKAAKAIQINETLLTTGNGYLNVRGSLEELPPGHCGGMYLAGIYDKSEADVEELVKCPMWTDVSVWHEGGKFCLSCCQALEHEQVLDMRKGILHRRTTFKNPHGKILTLETSRLVFMHDPHRGYMRVKITPRNFSGQIRVLSGLNGQVYNRGFFPREQYKHLQLERIERGRNFMYLEMKTRERGIRIALGASWKMVSGSAPMLRWEPRIYGEKLTSEITIDAARGHSYAFEKLAVVMTSRDVPEERSRSMMREAICNLRSYVRTGAPVEIGRHLDVWSELWKQADVRIDGDEAAQKAFRYNIYQLLINGPAKPGPIGAKFLSSEGYMGHVFWDTEIFILPFYIHNFPAMARNALMYRFNTLPGAIVNAEKSGCEGARFAWESATTGEDVTPRFASKLEKIIRFIYTGVEEEHIVSDVIYGVERYFRVTGDEGFLLHCGLEMVFLTARYWASRVTRVGERYEIHTVIGPDEFHEHVNNNAYTNWLVKWHLRLAAMLFKHVGKTAPEALRELEEKISLGDDEPARWLDISRCLKFTQNAETGLIEQFDGYFALKDHVIGRCDRSGHPVLPPGVTYRNIGRTQLIKQADVLLMMLLFPHSFSFEEKRANYDFYEPRTAHKSSLSHCTHAMMGLAVAERNNAYRYFMKTALFDLENLHDNTELGIHAASVGGSWQTVIHGFGGLLLKSDRIVLNPWLPKKWDRLAFRVKWRERTVHLDITHTEVLITIEAASEMTLPCTLYGKTYKICTNEPRTLSYCPPR
>NZ_CP017305.1|WP_069811497.1|1564333_1565380_-|glycosyltransferase-family-4-protein
MKKLRIAQISPLIESVPPKKYGGTERVVYYLTEGLVERGHEVTLFASGDSITSARLIAPVTQSLRLGRKIHSTIIMHMLMLSRVYEEMAGEFDIIHSHLEYLTLPYASRSRTPTVLTMHGRLDIPDYVDILKRYSSMAWVSISDSQRAPVPGINWAGTVYHGYPENLFDYNPDPENYFIYLGRFSEEKRPDEAIRLARACKIRLKLAAKIDAADKAYFKAKVEPLLDSPYIEYIGEVDDRRKGELLRNARALLNPIDWPEPFGLVMIEALACGTPVIVRRCGSSPEVITDGVSGFVCDSQLDFIHAIHNIGAISRAACRREFERRFTLRHMVENYETLYRNVIAAASA
>NZ_CP017305.1|WP_069811495.1|1560622_1564171_-|DNA-polymerase-III-subunit-alpha
MEFVHLHTHTHYSMQSSPIFPGELFAACKKQGMTTVAVTDYGAMFNMPELFGQARKAEVKLIMGAEVYLAGTDSRDGGRPATLILLIRDGVGYRNMCVILSRAARDGFSNGLPHVDRAVLEEYREGLVCLSAAHSGLVGRALLSGNEAEAASHASWYRDLFGEHFYLELQKHGAPYEEQLVPGTIHLAEKLGIPLVATNNVHYLDRRDSGCYRAMIANRTKERLASQNLQCLPGHENYFKSAAEMSALFDNAHGELDNTVKIAESCSYKFIDQDPNLPQFPLPEGFDSEKEYLRHLTWEGAREKYGSEDGAVPDDVKARVELELGVIEKMGYSSYFLIVSDLIAASRRLGYSVGPGRGSAAGSIIAYLTGITRIDPLKYKLLFERFLNPERISMPDIDIDFTPVGKQKVLEYTVQKYGAESVAKVVAIGTLGAKAAIRDAGRVLDVPLKAVDQLAKLVPSKPGTSLEDAFREVKELKRLVDTEPQYQQLMQYARAMEGRARNVSMHAGAVVITNGALEEQVPLYVSNKIETEERKYADEFDQNDIDGTKADSSDEKQVVTQFDKNCIEQAGLLKIDYLGLETLAVIDETLRLIKKRHGIDIDLEKVPIDDRQTFRIFQEGKMAGIFQFESSGMQSYMTRLQPTTIGDIIAMSALYRPGALNAVIDEHRNAVDLFVDRKHGREEIDYMHPMLEEILKETYGVIVYQEQVMQISQVMGRFSLGKADNLRKAMGKKDPKLMQKFKEEFVNGAVSIAVNEALASRIFDLMAEFAGYGFNKSHSAAYGVLAYWTGYLKAHYTIEFVTAILNSEIGDTERMKHLTDEAKGFGIFTLPPSINKSDALFSVDEHKGKPCIRVGLSAIKQVGGGARAVVAARLRREGKPFLNLFDLTASVDLRAMNRKALESLIQAGALDEIDPNRARLLANVDKAIRFGQIQNKAVTLGQGGFFNDDFSDEQAGVHYPDLDNAEPMPDSEKLQHEKRLVGFYLSHHPLDRFRRDWEAFANLTLDMREVTPSKLYKAIGVIVSVKPYQDRKGKQMLFGVLEDFTGKADFTVFASVYEQYRHMLQPDEAVMLSVEAEAKDGSLKLLVREVAPLKKVRSAMVRKVVLRIDADDSTQLGKLQQVREIFEKHKGGTPVDFEVRATIGSCNETLKLFARNTPIEADDELLDQLEELLGPDNVKITG
>NZ_CP017305.1|WP_069809894.1|1560193_1560523_-|thioredoxin
MSGKYFEATDKNFQAEILGSDKVALVDFWASWCGPCMMLGPVIEELAGDYEGKAIIAKLNVDENPNTAGQYGIRSIPTMLIIKGGKVVDQMVGALPKNMISKKLDEHIG
>NZ_CP017305.1|WP_069809892.1|1559170_1560106_-|thioredoxin-disulfide-reductase
MDNEIRDVVIIGTGPAGYTSAIYTGRANLKPLVIDGHQPGGQLMITTDIENFPGFPEGIPGPELMGRMRDQAARFGVEFQFGSVSEADVSRSPFSLTLDNGQEILARTLIIATGANAKWLGIESEEKYRGRGVSACATCDGFFFRNCRVFVVGGGDTAMEEALYLTKFASEVVLVHRRDEFRASKIMSLRASKNEKITTMLNQVVDEILGDDMKVTGIRLKNVKNGELTEHACDGVFMAIGHEPNARLFKGQLDMDDYGYILTKCHSTETSVKGVFACGDVQDYTYRQAVTAVGTGCMAAIEAERFLESIR
>NZ_CP017305.1|WP_069809891.1|1558368_1558821_-|hypothetical-protein
MTIKDIAFFAGLFLGSTLLLSTTYVFVKRQAFGLGGVVLIIFGSFMVGLSIWTSFEFSFKKDGSITAKYTQEIKEDLGEKTADINGNIEFLKLKIAELSQDVAALKIANPKAAPSKELVKSREVKEQEFKRNSDYSILVFIKMLKKKQRA
>NZ_CP017305.1|WP_084022348.1|1557733_1558087_-|addiction-module-protein
MASPKHSTANGDGLDVKLMFLCFVMCIITLKGFFSRRKAKLKAHDRVIEEALTLSADIRLNLIEKLLMSFNQPADEEIDRLWAGNAELRIAQVEEGTVKFVIVEEVFAKPSRKYKFS
>NZ_CP017305.1|WP_069811489.1|1557405_1557699_-|nucleotidyltransferase-family-protein
MKNVTEIQTALKPYMAKLKEEYQINRLGMFGSYVRNEQTSGSDLDLLVTFTSTPSLFKFIALENYLSDLLGVKVDLVMESALKPRIGKYIRKELVIL
>NZ_CP017305.1|WP_069809889.1|1557061_1557409_-|DUF86-domain-containing-protein
MSINREFIDYLEDILDAMVKIEKFIADQSFYDFAQDDKSQFAVIRAFEIIGEASKKIPEHVKEKYRNVPWRVMAGMRDKLVHEYFGVDIEVVWKTATEDIKDLKPIIHGIIKNYQ
>NZ_CP017305.1|WP_069809887.1|1556423_1556633_+|hypothetical-protein
MTVKFSVFLATRHIPRLKISACPTASNGALWLLVDDTADDGDGFRVATGIGGVWRAEYTHGIDKPPTCA
>NZ_CP017305.1|WP_157098374.1|1569665_1571066_-|DUF262-domain-containing-protein
MRKPDFQRETSDWDKGKIASFIKSFIDGDLIPSIILWQAGQYTFVIDGAHRLSALIAWVNDDYGNGFISQSFFNHEVDNEQKRVAEQTKRHVDKEVGSYASFMAAIRNPEQAKPELLASANKLGFLSLQLQWVTGSAEKAETSFFTINQKATPISDTEIALLKARKKPYAMASRAILRSGSGHKYWDSFSPEIQAQVERLAKEINENLFTPEMKTPVKTLDLPLAGKGYSSRTLPLIFDLVKLSNNVSETEVSEDLDGNETIRFLKSTIKVIHRFTTTHPSSLGLHPAVYFYSEKGRYQPTAFMAWIEIIKDFDKRGYFDRFTEIREKIESVLIRYKYFTNQVTVKYGSGLKGYKQLKEVYERMIDMIENNTDLADIGVELKKRFSYLNLEDKGEQSQSKEFNQNTKSEVFLKSALESANRCKICNGYIHLNSITIDHIDRKEDGGIGVADNGQVTHPYCNTTYKN
>NZ_CP017305.1|WP_157098375.1|1571062_1571200_-|hypothetical-protein
MSNVNLDALIKREDFAVEGGSVAQNLADKLKVSELVKGESFFILL
>NZ_CP017305.1|WP_157098376.1|1571257_1571437_-|hypothetical-protein
MKTGIVIEKDGDGYLARVEGHQNLFAFAYSEKDTLMELKNVVEIIIDYHLEQVNDERVI
>NZ_CP017305.1|WP_069809902.1|1571625_1573509_-|biotin-attachment-protein
MKKIRFMDVSFRDGFQSCYGARVKTEDFLPVLEAAVEAGTDNFEIGGGARFQSLYFYCQEDAFEMMDACRRVVGPDINLQTLSRGANVVGLVSQSRDIIDLHAKLFKKHGVSTIRNFDALMDVRNLAWSGQCIVDAGLKHQVVVALMGLPPGLNESYCHTPQFYLDKLKEILDAGIPFDSVAFKDASGTTTPAVIYETVKGARKMLPEGTVLQFHTHDTAGMGVACNYAAIEAGIDIIDLAMAPVSGGTAEVDILTMWHRLRGTDFTLDIDQEKCLKVESIFIEHMDKYYMPPEAKEVNPVIPFSPMPGGALTANTQMMRDHDTLHFFPEVIRNMREVVAKGGFGSSVTPVSQFYFQQAFANTVQGPWKKIVDGYGKMVLGYFGKTPAAPDPEVVALAAEQLGLEPTVQDVHDINDRNPELGIEHNRKLLEEAGLEATDENIFIAATCGAKGIGFLKGDKPMGIRYKADVEAEEKAKHSEEELKVTSHGNSLQDRLQELIRPASRSSLSGNYLVMVDGKSFNVVIADGVAMAQSVASGLQPFVMPQMAAPAPQLQHQGTPVLPSMPGNVFKMEVKAGQKVEEGQEVAVMEAMKMESPVKAPVSGIVTVVLAKPGDTLSANQPLMYIE
>NZ_CP017305.1|WP_069811499.1|1573616_1575149_-|fumarate-hydratase
MKQFRDSMIALITETSANLPSDVRKAIAEAAAKEAPDSRAGLAMSAITLNIDMAVDNVAPVCQDTGMPTFFVHAPKGADLLAMKRDIEAAIAEATRTGKLRPNAVDSLTGKNSGNNLGDHVPVIHFEPWERDEIEVKLILKGGGCENKNIQYSLPAEIPGLGRAARDLDGVRKCILHAVYQAQGQGCSPGFIGVGIGGDRTSGFELAKKQLLRSVDDTNADAVLADLEAEILDKADTLNIGPMGFAGKVTLLGCKIGKSHRVPASFFVSVAYNCWAYRRLGVIVDPQEGAITEWQYRYPGEIKRMAHGVGIPLTGREVVLRAPISEETIRSLKVGDIVIVDGEIHTGRDAFHHYIMHHDLPEGLDIRGGIIYHCGPVMLKNEAGEYRVVAAGPTTSIREEPYQSDVIEKLGLRAVIGKGGMGPKTLAGLQKHGAVYLNAIGGAAQYYARCIEKVTGVDFLEEMGVPEAMWHLQAKAFPCIVTMDAHGNSLHQQVDEESFAKLESLGSAKD
>NZ_CP017305.1|WP_069809904.1|1575954_1577502_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MIQPAEALRRPEAYPHPVSADITVVETHISWIFLTGEFAYKLKKPVSLGFLDFSTLERRKHFCHEELRLNRRLCPELYLDVLPVTESEGKLRIGGEGEAVDYVIRMAQFDRNFELDRLLRNNELTASQIDEAAAVIAAFHAETPRADPAATFGTPEVILRPMLENLDLTEEVARTIEERSDIEKLRHWTLAEHRRLSGVVRERKALGMVRECHGDLHTGNMVIRDGEIVIFDCIEFSHALSIIDVMSDVAFLFMDLEHSGHPELAWHFLNGWLSKNGDYSGLQVLRLYCVYRAMVRAKVTSIRLAQESDEEAKSKTRAEHHSYIQLALGYTRQRTPMLLLTHGVSGSGKSLISSKLADRGGFIHIRSDVERKRLFGIDSLERSDEKGFDIYTPEATQQTYAAMLDAASTALSAGFPVIVDATFPDSHRRAPFIRLARTLECRCRILCFHASREALRERVRTRHEAGSDASEADLRVLEAQLHTSAPPDGDEKALCINVNTEGKVQIEALLAALER
>NZ_CP017305.1|WP_069809906.1|1577605_1578481_-|rubrerythrin-family-protein
MNQLPETDLRFITRFQKNEITEHHIYKNLARRVEGVKNRRIFAQISEDELRHYNVWKKFTGKDVEPDRFRIWLFSMIAMLFGFTFAVKIMEGGEQNAQMEYERVASMGSEIRGLIEDEEEHEQALIAVLDEERLQYTGSIVLGLNDALVELTGALAGLTFALQNTQLVALTAMITGFAAALSMASSEYLSTKAEPGTKNPLKASIYTGVAYLIAVAVLIVPYLFLANIYLSLALAFGGALVVIALFNFYVSVAKSVPFKNRFLEMAGLIVVVSGISFLAGLGIRYFFGIEV
>NZ_CP017305.1|WP_069809908.1|1578756_1580646_-|molecular-chaperone-HtpG
MSSNTTSPVREFEYKAEMKQLLDLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEGLERSGDLKITITVDKESGNFVIEDTGIGMSEDELISNLGTVAKSGTLGFMEALKEQQKEGQRLDANLIGQFGVGFYSVFMVTDEVTVETRSLESGSQGWRWKSSGQGSYTIEPVEREARGTRISFTLKEEFKEFAEEYRIEQVIKKYSNFVEYPICIGSRQINSMTALWQRPKSELKPEEVNEFYKFIANDFKDPLDYLHVSVEGAVSFKALLFIPSEAPMELLYNQGALEKRGPQLYVKKVLIQNECRDLLPEYLRFVSGVVDTEDLSLNVSRELVQASPVMAKIKQILTSKLLGWFDTIAKEEPEKFRTFYNAFGTILKIGLNTDFTNRDKLIDLLRFETTKTAEGEYVTLKQYSERMAEGQTEIYYHSGSSRAQMLAHPNLEYFKKRDIEVLLLSDPVDVFVIPSIFEYDKKPLKSIEKAEIDMSTVEPEGERLGAEGTVGVISLFKEVLGDRIADVVESKRLVSSPVTLVSGKDAMDSQFEKMMKMMSKDADMPASKKILEVNTAHPIIRNLAGKHAVGLSTDPVVRAAVMQLFESALLLEGDLESVADYVSRMNELVEAATRA
>NZ_CP017305.1|WP_069809910.1|1581036_1581933_-|hypothetical-protein
MKRLLLLSLSVLLTGNVAFGADTTASATIGDITNDNSNNATALSGGTFYNSSGGSVSQNFEASQPIPYLPGTPGVGATALTLFNLKGYPAQALGATLLSKNMVYASHHDVALGVSGGTKIIFNASFPASRSANKDRNVYINLSGVGRGEVIGSLTVQSRKDKADEVDFSTLLFDARQYIAGVRDLKGYNVTLLSVPSTISIALGVDGKASGATLAPLASGLINGPLGVMAGLGSGFTSNEGVTAPTALIGCTFLVLVDSEQSNVVNLLSNKNEPDESNGNGYSNSKKKYEAIQKDDGE
>NZ_CP017305.1|WP_157098378.1|1582012_1582714_-|hypothetical-protein
MTKVACQSRHKAGVFFDNDLKKKTKNSQKSMGDLIMKKTIITAMVAVSALGFSGTSFAVGAAAAAPDLFSNNDIELDVSLINETNDFNVDVDKSVDIDVDKRVRFDSSINADDDAPAAGGNLQVAYDAPAVGGDMIDVSSVAFALQLGDAESTYADLDFMGSGGVIAGSGPAAAAADASPLGGAAAAGGDSGNVNITATSGAITTGAVDINLSNTATALGVGGSYNYNAAVTP

Crispr_ID: NZ_CP017305_6

• CRISPR_ID: NZ_CP017305_6
• CRISPR_location: 2359906-2362375
• CRISPR_type: TypeI-E
• Repeat_type: I-B,III-A,III-B
• Spacer_info: 40 spacers
• Cas_protein_info: cas2,cas1,cas5,cas6e,cse2gr11,cas8e,cas3

Consensus repeat of NZ_CP017305_6

Consensus_repeat	Method
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CRISPRCasFinder
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CRT

spacers of NZ_CP017305_6

>6.1|2359934|33|NZ_CP017305|CRISPRCasFinder,CRT
CCGCTCGCGGCTGATGGTGAGTTTTTGCTGTGC
>6.2|2359995|33|NZ_CP017305|CRISPRCasFinder,CRT
CGTCAGGATCGAGCACGTTGGTACTGGCATAAG
>6.3|2360056|33|NZ_CP017305|CRISPRCasFinder,CRT
CTACATCGCGCACGGAAAAAACATCACCTGGGA
>6.4|2360117|33|NZ_CP017305|CRISPRCasFinder,CRT
TTTTCAAGTGTGTACAAATTTAGGGCTACATAC
>6.5|2360178|34|NZ_CP017305|CRISPRCasFinder,CRT
TACATATTCATGTAACTACATAACAGCACAACTG
>6.6|2360240|33|NZ_CP017305|CRISPRCasFinder,CRT
TCGAAGAGGTTCCTTTACATTGGAGAATTCCAC
>6.7|2360301|33|NZ_CP017305|CRISPRCasFinder,CRT
CCTTTTTCATTGACTACTTGCAAGTTTATCGAG
>6.8|2360362|33|NZ_CP017305|CRISPRCasFinder,CRT
TAGCTGAAAAATCGGTCAAAAACGCTTTCGAGG
>6.9|2360423|33|NZ_CP017305|CRISPRCasFinder,CRT
TATCGCGTTCCGTAATACGGGATTACAGGGATG
>6.10|2360484|33|NZ_CP017305|CRISPRCasFinder,CRT
CACATTAAAGCGATCATACGCCGCGCGACTTGT
>6.11|2360545|33|NZ_CP017305|CRISPRCasFinder,CRT
CCCGTCCATGTGCCTGGATATCTTGCATATCCC
>6.12|2360606|33|NZ_CP017305|CRISPRCasFinder,CRT
CCGGTCAAACGGCGGCTGCTTCGGCATACTGAT
>6.13|2360667|33|NZ_CP017305|CRISPRCasFinder,CRT
TTTCCGGCATCTCGTCCGCGACGAGCGCCAGCT
>6.14|2360728|33|NZ_CP017305|CRISPRCasFinder,CRT
CCCGGCCTTGCTCCACTTCGTGAAGTCCGTCGC
>6.15|2360789|33|NZ_CP017305|CRISPRCasFinder,CRT
TATTTATCTATATTTTCGTACCATTGCCGTTCT
>6.16|2360850|33|NZ_CP017305|CRISPRCasFinder,CRT
TGGCTTAACGGAATTATTAAAGACGTTTGCCAG
>6.17|2360911|33|NZ_CP017305|CRISPRCasFinder,CRT
CGGCGTCCAAGAAGGAAACGACGAAAGCGTACT
>6.18|2360972|33|NZ_CP017305|CRISPRCasFinder,CRT
CTTACACGATCACATATAAGCATTATAAAAAAA
>6.19|2361033|33|NZ_CP017305|CRISPRCasFinder,CRT
CTTCAGAAGCGAATTACCCGATCAGGAAAGTTT
>6.20|2361094|33|NZ_CP017305|CRISPRCasFinder,CRT
CCCCGCGCTGGGCGGGGCTGGTGGGCTGATTGC
>6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT
TTCTTCAGAGCCAGAAGATTTCTGCTTCTACGA
>6.22|2361216|33|NZ_CP017305|CRISPRCasFinder,CRT
TATTTCGACAAATTGCTTGCTATTGATGATGAA
>6.23|2361277|33|NZ_CP017305|CRISPRCasFinder,CRT
TTTTGTGCTGCGCGCGGCGTTCCTGACAACCCC
>6.24|2361338|33|NZ_CP017305|CRISPRCasFinder,CRT
TCGGTCAGGTGCTGATCGACCATATCCGTGACG
>6.25|2361399|34|NZ_CP017305|CRISPRCasFinder,CRT
CTGGCGAGCGCATCGTGTTGCCGATTTCGGACGA
>6.26|2361461|33|NZ_CP017305|CRISPRCasFinder,CRT
CTCAGCAAGCTCGCGCGTCGCTTCATCATGGTC
>6.27|2361522|33|NZ_CP017305|CRISPRCasFinder,CRT
TGGCTTTTACGATTTGTCGAACGGTTTGGGCAC
>6.28|2361583|33|NZ_CP017305|CRISPRCasFinder,CRT
CTCCACCGATGACAAAAGAAGTTCCTCAAGTCA
>6.29|2361644|33|NZ_CP017305|CRISPRCasFinder,CRT
CAGAATGCACCCCTCGACGATCCGTAATCGTCA
>6.30|2361705|33|NZ_CP017305|CRISPRCasFinder,CRT
CTTTGCTTTTTTACGGTTTTCCTCCCACTGGTG
>6.31|2361766|33|NZ_CP017305|CRISPRCasFinder,CRT
TCCGTCAAAGAACGGCGACATCTATGTGATCTC
>6.32|2361827|33|NZ_CP017305|CRISPRCasFinder,CRT
CTTTGACTGTGGACTCATAGGAAGCGTACCGGT
>6.33|2361888|33|NZ_CP017305|CRISPRCasFinder,CRT
CGAGATGGGTACGTCGCCCTATACGGTCGATGA
>6.34|2361949|33|NZ_CP017305|CRISPRCasFinder,CRT
CATCAAAGGAGAGTCATCATGACAAGCGAAGCA
>6.35|2362010|33|NZ_CP017305|CRISPRCasFinder,CRT
TTTAAGCTCCTTTTTCTTATGCTGTTCCAGACT
>6.36|2362071|33|NZ_CP017305|CRISPRCasFinder,CRT
CTCGCCCACATGACCGTAACCGCCAGAACCATC
>6.37|2362132|33|NZ_CP017305|CRISPRCasFinder,CRT
CGGAGATGGCATCATGACAAACGCAGAAAAACT
>6.38|2362193|33|NZ_CP017305|CRISPRCasFinder,CRT
CGGGAGTTCCGACATACGTCGCTGCCGCCGACA
>6.39|2362254|33|NZ_CP017305|CRISPRCasFinder,CRT
TTTTATTTCAGTCACCAGCACCGGCTCCGTCTC
>6.40|2362315|33|NZ_CP017305|CRISPRCasFinder,CRT
CTCAGGCCAATAATAACTGAAACGGGTATCGCG

CRISPR arrays and Neighbor proteins around NZ_CP017305_6

CRISPR arrays

The CRISPR arrays of NZ_CP017305_6

>merge|NZ_CP017305|6|2359906-2362375|CRISPRCasFinder,CRT
GTCTTCCCCACGCCCGTGGGGGTGTTTCCCGCTCGCGGCTGATGGTGAGTTTTTGCTGTGCGTCTTCCCCACGCCCGTGGGGGTGTTTCCGTCAGGATCGAGCACGTTGGTACTGGCATAAGGTCTTCCCCACGCCCGTGGGGGTGTTTCCTACATCGCGCACGGAAAAAACATCACCTGGGAGTCTTCCCCACGCCCGTGGGGGTGTTTCTTTTCAAGTGTGTACAAATTTAGGGCTACATACGTCTTCCCCACGCCCGTGGGGGTGTTTCTACATATTCATGTAACTACATAACAGCACAACTGGTCTTCCCCACGCCCGTGGGGGTGTTTCTCGAAGAGGTTCCTTTACATTGGAGAATTCCACGTCTTCCCCACGCCCGTGGGGGTGTTTCCCTTTTTCATTGACTACTTGCAAGTTTATCGAGGTCTTCCCCACGCCCGTGGGGGTGTTTCTAGCTGAAAAATCGGTCAAAAACGCTTTCGAGGGTCTTCCCCACGCCCGTGGGGGTGTTTCTATCGCGTTCCGTAATACGGGATTACAGGGATGGTCTTCCCCACGCCCGTGGGGGTGTTTCCACATTAAAGCGATCATACGCCGCGCGACTTGTGTCTTCCCCACGCCCGTGGGGGTGTTTCCCCGTCCATGTGCCTGGATATCTTGCATATCCCGTCTTCCCCACGCCCGTGGGGGTGTTTCCCGGTCAAACGGCGGCTGCTTCGGCATACTGATGTCTTCCCCACGCCCGTGGGGGTGTTTCTTTCCGGCATCTCGTCCGCGACGAGCGCCAGCTGTCTTCCCCACGCCCGTGGGGGTGTTTCCCCGGCCTTGCTCCACTTCGTGAAGTCCGTCGCGTCTTCCCCACGCCCGTGGGGGTGTTTCTATTTATCTATATTTTCGTACCATTGCCGTTCTGTCTTCCCCACGCCCGTGGGGGTGTTTCTGGCTTAACGGAATTATTAAAGACGTTTGCCAGGTCTTCCCCACGCCCGTGGGGGTGTTTCCGGCGTCCAAGAAGGAAACGACGAAAGCGTACTGTCTTCCCCACGCCCGTGGGGGTGTTTCCTTACACGATCACATATAAGCATTATAAAAAAAGTCTTCCCCACGCCCGTGGGGGTGTTTCCTTCAGAAGCGAATTACCCGATCAGGAAAGTTTGTCTTCCCCACGCCCGTGGGGGTGTTTCCCCCGCGCTGGGCGGGGCTGGTGGGCTGATTGCGTCTTCCCCACGCCCGTGGGGGTGTTTCTTCTTCAGAGCCAGAAGATTTCTGCTTCTACGAGTCTTCCCCACGCCCGTGGGGGTGTTTCTATTTCGACAAATTGCTTGCTATTGATGATGAAGTCTTCCCCACGCCCGTGGGGGTGTTTCTTTTGTGCTGCGCGCGGCGTTCCTGACAACCCCGTCTTCCCCACGCCCGTGGGGGTGTTTCTCGGTCAGGTGCTGATCGACCATATCCGTGACGGTCTTCCCCACGCCCGTGGGGGTGTTTCCTGGCGAGCGCATCGTGTTGCCGATTTCGGACGAGTCTTCCCCACGCCCGTGGGGGTGTTTCCTCAGCAAGCTCGCGCGTCGCTTCATCATGGTCGTCTGCCCCACGCCCGTGGGGGTGTTTCTGGCTTTTACGATTTGTCGAACGGTTTGGGCACGTCTTCCCCACGCCCGTGGGGGTGTTTCCTCCACCGATGACAAAAGAAGTTCCTCAAGTCAGTCTTCCCCACGCCCGTGGGGGTGTTTCCAGAATGCACCCCTCGACGATCCGTAATCGTCAGTCTTCCCCACGCCCGTGGGGGTGTTTCCTTTGCTTTTTTACGGTTTTCCTCCCACTGGTGGTCTTCCCCACGCCCGTGGGGGTGTTTCTCCGTCAAAGAACGGCGACATCTATGTGATCTCGTCTTCCCCACGCCCGTGGGGGTGTTTCCTTTGACTGTGGACTCATAGGAAGCGTACCGGTGTCTTCCCCACGCCCGTGGGGGTGTTTCCGAGATGGGTACGTCGCCCTATACGGTCGATGAGTCTTCCCCACGCCCGTGGGGGTGTTTCCATCAAAGGAGAGTCATCATGACAAGCGAAGCAGTCTTCCCCACGCCCGTGGGGGTGTTTCTTTAAGCTCCTTTTTCTTATGCTGTTCCAGACTGTCTTCCCCACGCCCGTGGGGGTGTTTCCTCGCCCACATGACCGTAACCGCCAGAACCATCGTCTTCCCCACGCCCGTGGGGGTGTTTCCGGAGATGGCATCATGACAAACGCAGAAAAACTGTCTTCCCCACGCCCGTGGGGGTGTTTCCGGGAGTTCCGACATACGTCGCTGCCGCCGACAGTCTTCCCCACGCCCGTGGGGGTGTGCGTTTTATTTCAGTCACCAGCACCGGCTCCGTCTCGTCTTCCCCACGCCCGTGGGGGTGTGCGCTCAGGCCAATAATAACTGAAACGGGTATCGCGGTCTTCCCCACGCCCGTGGGGGTGTGCG

>NZ_CP017305|6|6|2359906-2362375|CRISPRCasFinder
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCGCTCGCGGCTGATGGTGAGTTTTTGCTGTGC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGTCAGGATCGAGCACGTTGGTACTGGCATAAG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTACATCGCGCACGGAAAAAACATCACCTGGGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTTCAAGTGTGTACAAATTTAGGGCTACATAC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TACATATTCATGTAACTACATAACAGCACAACTG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TCGAAGAGGTTCCTTTACATTGGAGAATTCCAC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCTTTTTCATTGACTACTTGCAAGTTTATCGAG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TAGCTGAAAAATCGGTCAAAAACGCTTTCGAGG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TATCGCGTTCCGTAATACGGGATTACAGGGATG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CACATTAAAGCGATCATACGCCGCGCGACTTGT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCCGTCCATGTGCCTGGATATCTTGCATATCCC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCGGTCAAACGGCGGCTGCTTCGGCATACTGAT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTCCGGCATCTCGTCCGCGACGAGCGCCAGCT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCCGGCCTTGCTCCACTTCGTGAAGTCCGTCGC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TATTTATCTATATTTTCGTACCATTGCCGTTCT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TGGCTTAACGGAATTATTAAAGACGTTTGCCAG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGGCGTCCAAGAAGGAAACGACGAAAGCGTACT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTACACGATCACATATAAGCATTATAAAAAAA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTCAGAAGCGAATTACCCGATCAGGAAAGTTT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCCCGCGCTGGGCGGGGCTGGTGGGCTGATTGC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTCTTCAGAGCCAGAAGATTTCTGCTTCTACGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TATTTCGACAAATTGCTTGCTATTGATGATGAA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTTGTGCTGCGCGCGGCGTTCCTGACAACCCC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TCGGTCAGGTGCTGATCGACCATATCCGTGACG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTGGCGAGCGCATCGTGTTGCCGATTTCGGACGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTCAGCAAGCTCGCGCGTCGCTTCATCATGGTC
GTCTGCCCCACGCCCGTGGGGGTGTTTC	TGGCTTTTACGATTTGTCGAACGGTTTGGGCAC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTCCACCGATGACAAAAGAAGTTCCTCAAGTCA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CAGAATGCACCCCTCGACGATCCGTAATCGTCA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTTGCTTTTTTACGGTTTTCCTCCCACTGGTG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TCCGTCAAAGAACGGCGACATCTATGTGATCTC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTTGACTGTGGACTCATAGGAAGCGTACCGGT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGAGATGGGTACGTCGCCCTATACGGTCGATGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CATCAAAGGAGAGTCATCATGACAAGCGAAGCA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTAAGCTCCTTTTTCTTATGCTGTTCCAGACT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTCGCCCACATGACCGTAACCGCCAGAACCATC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGGAGATGGCATCATGACAAACGCAGAAAAACT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGGGAGTTCCGACATACGTCGCTGCCGCCGACA
GTCTTCCCCACGCCCGTGGGGGTGTGCG	TTTTATTTCAGTCACCAGCACCGGCTCCGTCTC
GTCTTCCCCACGCCCGTGGGGGTGTGCG	CTCAGGCCAATAATAACTGAAACGGGTATCGCG
GTCTTCCCCACGCCCGTGGGGGTGTGCG

>NZ_CP017305|6|3|2359906-2362375|CRT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCGCTCGCGGCTGATGGTGAGTTTTTGCTGTGC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGTCAGGATCGAGCACGTTGGTACTGGCATAAG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTACATCGCGCACGGAAAAAACATCACCTGGGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTTCAAGTGTGTACAAATTTAGGGCTACATAC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TACATATTCATGTAACTACATAACAGCACAACTG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TCGAAGAGGTTCCTTTACATTGGAGAATTCCAC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCTTTTTCATTGACTACTTGCAAGTTTATCGAG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TAGCTGAAAAATCGGTCAAAAACGCTTTCGAGG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TATCGCGTTCCGTAATACGGGATTACAGGGATG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CACATTAAAGCGATCATACGCCGCGCGACTTGT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCCGTCCATGTGCCTGGATATCTTGCATATCCC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCGGTCAAACGGCGGCTGCTTCGGCATACTGAT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTCCGGCATCTCGTCCGCGACGAGCGCCAGCT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCCGGCCTTGCTCCACTTCGTGAAGTCCGTCGC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TATTTATCTATATTTTCGTACCATTGCCGTTCT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TGGCTTAACGGAATTATTAAAGACGTTTGCCAG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGGCGTCCAAGAAGGAAACGACGAAAGCGTACT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTACACGATCACATATAAGCATTATAAAAAAA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTCAGAAGCGAATTACCCGATCAGGAAAGTTT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CCCCGCGCTGGGCGGGGCTGGTGGGCTGATTGC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTCTTCAGAGCCAGAAGATTTCTGCTTCTACGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TATTTCGACAAATTGCTTGCTATTGATGATGAA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTTGTGCTGCGCGCGGCGTTCCTGACAACCCC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TCGGTCAGGTGCTGATCGACCATATCCGTGACG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTGGCGAGCGCATCGTGTTGCCGATTTCGGACGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTCAGCAAGCTCGCGCGTCGCTTCATCATGGTC
GTCTGCCCCACGCCCGTGGGGGTGTTTC	TGGCTTTTACGATTTGTCGAACGGTTTGGGCAC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTCCACCGATGACAAAAGAAGTTCCTCAAGTCA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CAGAATGCACCCCTCGACGATCCGTAATCGTCA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTTGCTTTTTTACGGTTTTCCTCCCACTGGTG
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TCCGTCAAAGAACGGCGACATCTATGTGATCTC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTTTGACTGTGGACTCATAGGAAGCGTACCGGT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGAGATGGGTACGTCGCCCTATACGGTCGATGA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CATCAAAGGAGAGTCATCATGACAAGCGAAGCA
GTCTTCCCCACGCCCGTGGGGGTGTTTC	TTTAAGCTCCTTTTTCTTATGCTGTTCCAGACT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CTCGCCCACATGACCGTAACCGCCAGAACCATC
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGGAGATGGCATCATGACAAACGCAGAAAAACT
GTCTTCCCCACGCCCGTGGGGGTGTTTC	CGGGAGTTCCGACATACGTCGCTGCCGCCGACA
GTCTTCCCCACGCCCGTGGGGGTGTGCG	TTTTATTTCAGTCACCAGCACCGGCTCCGTCTC
GTCTTCCCCACGCCCGTGGGGGTGTGCG	CTCAGGCCAATAATAACTGAAACGGGTATCGCG
GTCTTCCCCACGCCCGTGGGGGTGTGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017305.1|WP_069810735.1|2348052_2348751_+|magnesium-protoporphyrin-IX-methyltransferase	unknown	unknown	gnl|CDD|236059
NZ_CP017305.1|WP_069810752.1|2370508_2371240_-|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl|CDD|277343
NZ_CP017305.1|WP_169817638.1|2363432_2363624_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017305.1|WP_069810741.1|2356288_2356918_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl|CDD|273869
NZ_CP017305.1|WP_069810749.1|2367043_2367994_-|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NZ_CP017305.1|WP_069810744.1|2359561_2359897_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl|CDD|187779
NZ_CP017305.1|WP_069810746.1|2363771_2365154_+|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|236946
NZ_CP017305.1|WP_069810745.1|2362557_2363442_-|DUF4438-domain-containing-protein	unknown	unknown	gnl|CDD|379630
NZ_CP017305.1|WP_069810748.1|2365671_2366301_-|haloacid-dehalogenase	unknown	unknown	gnl|CDD|319790
NZ_CP017305.1|WP_069810736.1|2348915_2350556_+|magnesium-protoporphyrin-IX-monomethyl-ester-anaerobic-oxidative-cyclase	unknown	unknown	gnl|CDD|131081
NZ_CP017305.1|WP_069810740.1|2355755_2356292_+|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|187862
NZ_CP017305.1|WP_069810750.1|2368117_2369275_-|glycosyltransferase	unknown	unknown	gnl|CDD|213815
NZ_CP017305.1|WP_069810742.1|2357977_2358694_+|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|273842
NZ_CP017305.1|WP_069810747.1|2365258_2365675_-|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|181730
NZ_CP017305.1|WP_069810751.1|2369596_2370481_-|ATP-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234781
NZ_CP017305.1|WP_069810738.1|2351575_2354158_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
NZ_CP017305.1|WP_069810743.1|2358683_2359574_+|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
NZ_CP017305.1|WP_069810737.1|2350808_2351237_-|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl|CDD|223149
NZ_CP017305.1|WP_069811629.1|2366508_2366757_+|ferredoxin	unknown	unknown	gnl|CDD|379145
NZ_CP017305.1|WP_069810739.1|2354175_2355744_+|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|187860

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP017305.1|WP_069810740.1|2355755_2356292_+|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	1e-30	101.5	0.1
NZ_CP017305.1|WP_069810742.1|2357977_2358694_+|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	7e-53	173.8	0.1
NZ_CP017305.1|WP_069810741.1|2356288_2356918_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	1.4e-67	222.4	0.0
NZ_CP017305.1|WP_069810744.1|2359561_2359897_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	2.9e-42	137.5	0.0
NZ_CP017305.1|WP_069810738.1|2351575_2354158_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	1.8e-59	196.3	0.0
NZ_CP017305.1|WP_069810739.1|2354175_2355744_+|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	7.8e-105	346.2	0.0
NZ_CP017305.1|WP_069810743.1|2358683_2359574_+|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	1e-103	340.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017305.1|WP_069810735.1|2348052_2348751_+|magnesium-protoporphyrin-IX-methyltransferase	gnl|CDD|236059	PRK07580, PRK07580, Mg-protoporphyrin IX methyl transferase; Validated.	2.01838e-139
NZ_CP017305.1|WP_069810752.1|2370508_2371240_-|UDP-2,3-diacylglucosamine-diphosphatase	gnl|CDD|277343	cd07398, MPP_YbbF-LpxH, Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain. YbbF/LpxH is an Escherichia coli UDP-2,3-diacylglucosamine hydrolase thought to catalyze the fourth step of lipid A biosynthesis, in which a precursor UDP-2,3-diacylglucosamine is hydrolyzed to yield 2,3-diacylglucosamine 1-phosphate and UMP. YbbF belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.60696e-54
NZ_CP017305.1|WP_069810750.1|2368117_2369275_-|glycosyltransferase	gnl|CDD|213815	TIGR03469, HpnB, hopene-associated glycosyltransferase HpnB. This family of genes include a glycosyl transferase, group 2 domain (pfam00535) which are responsible, generally for the transfer of nucleotide-diphosphate sugars to substrates such as polysaccharides and lipids. The genes of this family are often found in the same genetic locus with squalene-hopene cyclase genes, and are never associated with genes for the metabolism of phytoene. Indeed, the members of this family appear to never be found in a genome lacking squalene-hopene cyclase (SHC), although not all genomes encoding SHC have this glycosyl transferase. In the organism Zymomonas mobilis the linkage of this gene to hopanoid biosynthesis has been noted and the gene named HpnB. Hopanoids are known to feature polar glycosyl head groups in many organisms.	1.41318e-62
NZ_CP017305.1|WP_069810741.1|2356288_2356918_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.86171e-86
NZ_CP017305.1|WP_069810749.1|2367043_2367994_-|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	4.98073e-97
NZ_CP017305.1|WP_069810744.1|2359561_2359897_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|187779	cd09648, Cas2_I-E, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	6.31107e-48
NZ_CP017305.1|WP_069810746.1|2363771_2365154_+|M23-family-metallopeptidase	gnl|CDD|236946	PRK11649, PRK11649, putative peptidase; Provisional.	2.01813e-41
NZ_CP017305.1|WP_069810745.1|2362557_2363442_-|DUF4438-domain-containing-protein	gnl|CDD|379630	pfam14505, DUF4438, Domain of unknown function (DUF4438).	5.34586e-168
NZ_CP017305.1|WP_069810748.1|2365671_2366301_-|haloacid-dehalogenase	gnl|CDD|319790	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive. This family includes the N-terminal phosphatase domain of human soluble epoxide hydrolase (sEH). sEH is a bifunctional enzyme with two distinct enzyme activities, the C-terminal domain has epoxide hydrolysis activity and the N-terminal domain (Ntermphos), which belongs to this family, has lipid phosphatase activity. The latter prefers mono-phosphate esters, and lysophosphatidic acids (LPAs) are the best natural substrates found to date. In addition this family includes Gallus gallus sEH and Xenopus sEH which appears to lack phosphatase activity, and Escherichia coli YihX/HAD4 which selectively hydrolyzes alpha-Glucose-1-P, phosphatase, has significant phosphatase activity against pyridoxal phosphate, and has low beta phosphoglucomutase activity. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.90903e-22
NZ_CP017305.1|WP_069810736.1|2348915_2350556_+|magnesium-protoporphyrin-IX-monomethyl-ester-anaerobic-oxidative-cyclase	gnl|CDD|131081	TIGR02026, BchE, magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase. This model represents the cobalamin-dependent oxidative cyclase, a radical SAM enzyme responsible for forming the distinctive E-ring of the chlorin ring system under anaerobic conditions. This step is essential in the biosynthesis of both bacteriochlorophyll and chlorophyll under anaerobic conditions (a separate enzyme, AcsF, acts under aerobic conditions). This model identifies two clades of sequences, one from photosynthetic, non-cyanobacterial bacteria and another including Synechocystis and several non-photosynthetic bacteria. The function of the Synechocystis gene is supported by gene clustering with other photosynthetic genes, so the purpose of the gene in the non-photosynthetic bacteria is uncertain. Note that homologs of this gene are not found in plants which rely solely on the aerobic cyclase.	0
NZ_CP017305.1|WP_069810740.1|2355755_2356292_+|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.59338e-33
NZ_CP017305.1|WP_069810742.1|2357977_2358694_+|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	1.05718e-77
NZ_CP017305.1|WP_069810747.1|2365258_2365675_-|aminoacyl-tRNA-hydrolase	gnl|CDD|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	9.10105e-66
NZ_CP017305.1|WP_069810751.1|2369596_2370481_-|ATP-phosphoribosyltransferase	gnl|CDD|234781	PRK00489, hisG, ATP phosphoribosyltransferase; Reviewed.	2.63337e-142
NZ_CP017305.1|WP_069810738.1|2351575_2354158_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.31872e-85
NZ_CP017305.1|WP_069810743.1|2358683_2359574_+|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.01019e-141
NZ_CP017305.1|WP_069810737.1|2350808_2351237_-|Hsp20/alpha-crystallin-family-protein	gnl|CDD|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	1.12338e-32
NZ_CP017305.1|WP_069811629.1|2366508_2366757_+|ferredoxin	gnl|CDD|379145	pfam13370, Fer4_13, 4Fe-4S single cluster domain of Ferredoxin I. Fer4_13 is a ferredoxin I from sulfate-reducing bacteria. Chemical sequence analysis suggests that this characteristic [4Fe-4S] cluster sulfur environment is widely distributed among ferredoxins.	3.94142e-13
NZ_CP017305.1|WP_069810739.1|2354175_2355744_+|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	5.7827e-81

Protein sequences

>NZ_CP017305.1|WP_069810744.1|2359561_2359897_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MLVVVANDLPPAVRGRMKLWFIEPRANVFVSGVRDSLARKVVDYLHEHCPPKSGLMIFNSSNTCPGYEIFGLGDTRKEITEISGLPLVIEKSAEPPPDNPNSLTPDVPKPQ
>NZ_CP017305.1|WP_069810743.1|2358683_2359574_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MKSNALGNEGNPARLLIKVTRDTLPQVKEKYPFLYLEKGRMEIDDSSIKWIDCDCNVVRLPVAMLNCILLGPGTTVTHEAVKVMAAANCGICWVGDDSLMFYASGQTPTSNTRNMTHQMKLAANPAKSLEVARQLFAYRFPDANLETKTLPQMMGMEGLRVRKFYEEMAVKYKVGWKGRRFEPGNFEMSDTTNKILTAANAALYSIIMSAAHSMGYSPHIGFIHSGSPLPFIYDLADLYKQQVSIDLAFAMTAEMAGYYDRHKIAAEFRKRVIEIDLLGKIGPDIETILGKKQCLS
>NZ_CP017305.1|WP_069810742.1|2357977_2358694_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSNPFILLWLEAPLQSWGADSRFGRRDTLDFPTKSGLLGLLCCALGAGGEQRELLAEMAPLRQTVLAFQRERGERPPLLRDFQMVGSGYDEKDKWETLLIPKKRDGGGAVGGGTKMTYRYYLQEATFATALEVPAARAEEFAEALKAPVWDIYFGRKCCAPTDLVFRGEFDSEAAALEAASSIAKEKSLREAFRVRDYAPGDQSEGEVVALNDVPVQFGTRKKYRERRVTIIHYSDEE
>NZ_CP017305.1|WP_069810741.1|2356288_2356918_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MIATILTLSRKDVNALRITDSYSLHRVVYSLFEDVRSEAEKRSSVPSGFLFADKGGDAKGRQILILSDRPPLPPAHGELVSRPVPEEFLQHRFYKFEVTLNPTRKENKSGRRIPIKTREEVAAWFGSKSLESWGFSVDPARLDVRMLPVMQFSKQGDRPVTHGAASVSGMLRVENRDLFIESFRKGIGRGRAFGFGLLQIEPLKDDSNH
>NZ_CP017305.1|WP_069810740.1|2355755_2356292_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MDNEKEKKTGRPEKFVEFVIGLCQKDKGAAAALRRADNPATEYQSWEYLAGFNIDLENPFERIPYATIAAAISRAKAERNGSAGIGKAIAYCYDDKSASDQAKARLRRLLACDSVKEACRILRPLFSLIDSKAAVTIDYSRLLKDLIDFGYDSNKVKTKWATDFYRHAAESATEEVEA
>NZ_CP017305.1|WP_069810739.1|2354175_2355744_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MHNRFNLIDEPWIPAVGKGFASLGDIFSDPDIPALGGNPVQKIALTKLLLAIGQAACTPESTEALEQLDAETFRRACRAYLEKWRDRFWLFGERPFLQMPAVRRLIEERKQTELKAVPAAPAKKKEDAEKKAEENALPRPIGTGFFPDLPAENNTILSQFQLLETTEPAEMALFVVTLMNFAFGGKRIEKNLAPLTHGFTGKSVSAKAGPSIGNYVGYLHSFLTGPTLTDTLLLNLLSREQIRDNPYWKSGLGKPPWELMPEGEDCVAANHLKNSYMATLLSLSRFVLLDGEAIYYVEGLQYPSHKEGWREPGMTISDQEKQLKVLWVDPDKRPWRELPSMLAFLESSENKGFECQFIRYGLTRATRKHPQVGIWSGGLRVSANSGDQSVKQDNDFVESLFLFRSSEIGKPWYDRFKLEMESLDQLSRKVYAATRSYFDKQNMDGGDLASNASGLFWQLCERRFPELVDACGEPDKLPAIRKATAALALQSYDTYCPKETARQIDAWAECRPNFAKHFINNR
>NZ_CP017305.1|WP_069810738.1|2351575_2354158_+|CRISPR-associated-helicase/endonuclease-Cas3
MRYPKSNRKPEAPAEHPPLPLENCLAKSRKIDADRSVAGRTVLDHCRIAGEVARELIARSPAYLREPFFPGGSALVAACHDLGKVCPTFQKKIHKAIEGADPTILDALNDVDPEIEKNWGGHAGVSQCALEALEAGKTVASIAGCHHGYAPKLGGRTADAESFGGAAWQAKRTRLLELLMEATGERLPEIRDPLHARVLAGLTSVADWIGSGAIFDDPGEPWQNRVAAAVDTAGFTPPLLAPGLSFREIFPFEPNPIQRGLIEAACRPGLYILEAPMGIGKTEAALYAAYALVAAGKARGIYFALPTQLTSNRIHGRVERFLDRVLEPDSPHRAALLLHGNAWLQEFDLGAEAAPGCSWFSSAKRGLLAPFAVGTVDQALMASMNVKHGFVRAFGIAGKVVILDEVHSYDAYTGTILDRLVGELRRLRCTVIILSATLTGERRSALLGAERSAEAAYPLITALPADAPEPLEIAPETTAGNEVTIRQTLDCEAALDEALDRADSGQQVLWIENTVSEAQEAYKLLAARSSGMAIECGLLHSRFIHRDREALEEEWVTRYGADGAAARRERGRILVGTQVLEQSLDIDADFLVTRLCPTDMLLQRIGRLWRHSFHQRPAGARCEAWIVSAQFEAAEQNPGEAFGNSAKVYSPYVLLRTLQAWAGVETLSLPGDIRGLLERTYEAKPESEAMAKHKAELQKRKEMLETFALQSVSPGLGAKPDTNVTTRYSDIDSVELLLLQSVSHNHAAGETTVTLLDGKTLTLPHDFAAGKKREQRKLAARLATQTLQVADYAAPTAPGRNTLTWLKPYFYLGDPSKSESLLRVAIVGEGGQLRLPGGGAASGDYELSYNPRLGYQYKKR
>NZ_CP017305.1|WP_069810737.1|2350808_2351237_-|Hsp20/alpha-crystallin-family-protein
MNLKLYGRDPLKMFEDVFNERLTPFISSMGSMMAPNFKVDISEDEKAVYLSADIPGVKKEDVKVTMEDDVISICAERTQEEEDKKKNYHRVERSWGSLSRSFALGDNVDAENITANYDNGVLKIVVPKKEPEEKKSKEIAVS
>NZ_CP017305.1|WP_069810736.1|2348915_2350556_+|magnesium-protoporphyrin-IX-monomethyl-ester-anaerobic-oxidative-cyclase
MKILMIQPNYHSGGAEIAGNWTPSWVAYIGGALKQAGFNQVKFVDAMADDLPDETIEEIIRKNQPDVVMTTNITPSIFKAQDIMKIAKKVNKNIRTIMGGIHSTFMYPQVLTEAPETDYVVRGEGEEVTVNLMKAIAAGNDKETRGDITGIAYIDEKGEVFATAAHPVIEDLDTLSPDWSLYDWDKYIYTPLNCRLAVPNFARGCPFTCTFCSQWQFWRRYRARSPKNFVDEIEVLVKKYNVGFFILADEEPTINKQKFVSLCQELIDRKLDVTWGINTRVTDIMRDEDLLPFFRKAGLVHVSLGTEAASQMNLNRFRKETTIEENKYAIKLLQKNGIVAEAQFVMGLEHETPETIEETYQLCKDWDPDMANWTIYTPWPFSDLFKELGDRVEVRDYSRYNFVSPIIKPDNMEREDVLKGVLKSYGRFYARKTFFSYPWIKDPYVRKYMLGCLKAFAQTTLTKRFYDIDRVKTKNRKIEIDLGFDQSRILTQAEVKNLKELRPEMVADMSFGLKEAGYQREHQEHNWDEFDETTIKDRTSSTVRNC
>NZ_CP017305.1|WP_069810735.1|2348052_2348751_+|magnesium-protoporphyrin-IX-methyltransferase
MSSPSFNVEEHKKMLQSYFNGQGFQRWASIYGNDKLSTVRSTVRQGHAVMMDKAFEWLQKTGLAKGSKILDAGCGTGLFTIRLAKSGYRVKAADIASQMVNKTKEDAEKAGVAGNIEFEVSSIESVSGTFDAVVCFDVLIHYPAEGFAHAFSNLASLTKGPIIFTYAPFNNILAFQHWIGGFFPKKERRTTIQMIKDKEMQRVLGELGLKIVSQQKISFGFYHTMLMHVARR
>NZ_CP017305.1|WP_069810745.1|2362557_2363442_-|DUF4438-domain-containing-protein
MLATNENRLVEILLQCQPGQPRTRGTWEVDHQGTPFILPSIGGITLNLQVGDPAFGWEGDHIEPGVSCTADTHKPYEHPNVTVQMLSCVGNTATIVSGEAKGESGVVLGHHGGSEHIIVDFPRETKEKMAYGDTIMVRSKGQGLKLTDFPQISLFNLDPSLLAKMKITVAEDGVLEVPVTTLVPAYCMGSGIGSAHVAKGDYDIVTSDPDAVREFGLDRIRFGDFVALLDQDNRYGRAYRKGAVTIGVVVHSDCREAGHGPGVTTIMTSATPVIRPVIDPKANIADLLGIGTRL
>NZ_CP017305.1|WP_169817638.1|2363432_2363624_+|hypothetical-protein
MQAWRNQEFDDEKTRQRSAFTAAKMTSGKTVRRGSKMKKINAGWRNQENNQQKENFFPRFAQI
>NZ_CP017305.1|WP_069810746.1|2363771_2365154_+|M23-family-metallopeptidase
MRRSALFRSRPLLLASSTALLVVLFFSVNLILSATSRQASPENQSASSVQTLFKSIGLGGDDELGLNDESDKVTLDEGENDPASKIEKRTLKKGESVYTILTAAGLTPSEIHRLTVQLKGSPALKGLKAGKTYEFETGRNGKFVRFSLQSSPYETLHIVRDEQTGKLSAEREAIEYDTRVATLEGTLNSSLSSELRSRNRSSLNPKLRKILSARLNFRKDIQAGATYRILFQEQWSGTDFIGTGDILAVEISSKGRNFNAYQFTNAKGDTAYYDEKGRAIMQGRTMFIQPCRFSRVSSGFGYRTHPVTGRRQYHGGVDLAAPTGTPVKAVADGRIIFRGRKGNAGNMITIAHSGKVHTMYLHLSRYASGSRYGKKVKQGDIIGYVGSTGRSTGPHLDFRIIRNGRPQNPLVALKQTAPRRSLSPSELHRFMARVQTYHQQLGSERPVMVADTGKQRETLL
>NZ_CP017305.1|WP_069810747.1|2365258_2365675_-|aminoacyl-tRNA-hydrolase
MIRIAGGVSVDENEIEIKAMRSQGAGGQNVNKVETAVHLRFDIGASSLPPELKERLARLKDHRITREGVIVIRAQRYRTQERNRQDAIERFQGILTKALVEQKTRKVTKPPKSASAKRLEAKAKRGELKASRKSIGDE
>NZ_CP017305.1|WP_069810748.1|2365671_2366301_-|haloacid-dehalogenase
MGIILLDIGNVLVNVDFMPFCRAVSREGEPGAAAIVGRYCQGELKDRHDTGRTGSHEYLAMIAADPLTRDLPLDRLRFAWQDIFTPTPGSAEAVEALRRRHRLWIMSDTDPLHFAFLIDRFPVLRNMDRYFLSYEHGWLKRSPEAFRYVLDSSGLDAAEFLLIDDREVNTRTCAGFGIQSILFRSWQETLASRELAAFSQHSVHVEAHR
>NZ_CP017305.1|WP_069811629.1|2366508_2366757_+|ferredoxin
MANNALKHTANAPGPFYVTSPDDPDGQGCNGCTICYNAAPDFFAEDEEGYAYVAQQPESEADIALCREQMDACPTNAIGDDG
>NZ_CP017305.1|WP_069810749.1|2367043_2367994_-|WD40-repeat-domain-containing-protein
MGFLSKIFGKKEVELKRPQVREDAALIKTLAGHEDRVLGVRFSPDGKKLVSGSFDEKVKLWNVETGNAIHTMSGHTTWVKCVDYSPKGDKVASGSIDSTVRIWDVVTGKCLHVCKGHDIEVRMIAFSPDGKTVASCSRDTTIKFWDVETGNELKTLFGHKSYIECIAFSADGKKLVSCGEEPVVKIWDLESGKNIANYPTGDTLSHFVAFSPDGSKIALCGRDAKVKVLDATSGQMLKVLEGHEDGVRSLCFNPAGTLIASAANDESVRLWDVAKGSLVHTYRGHTHEVQSVAFSPDGKVIASGSDDFKIKLWGVV
>NZ_CP017305.1|WP_069810750.1|2368117_2369275_-|glycosyltransferase
MIFYQLFILGSLLVFLGIVLKNLGDLPRLPAGPGDGAFAPKVSLLVPARNEELNIEACVASLLEQRYPDFEVIVLDDHSSDGTLDVLRRIAATPSGAKLRIIEGRPLPAGWHGKAWACQQLGEAASGKLLLFTDADTCHQSDALPRAVEAMQRSGAGMLSLTPAQQMESFWEKLIVPLVYHILFSYLPIAMVSKSPSPAFCYAIGQFILFRREAYERIGGHRSVCNNIVEDVWLCKAVKRSGGKVTAFDGTDAVSCRMYQGFGEVWQGFSKNLFAGLGNNVVGLFALMALVALLYLAPYGFLAISVLHGDRSLTLFWLPLVQIAVALLIRLIIAAKFRQPLWPVALHLFSQAMLLLIAANSFRLSVFGKGPEWKGRNYPLSGQSL
>NZ_CP017305.1|WP_069810751.1|2369596_2370481_-|ATP-phosphoribosyltransferase
MSNSNKVLKLGLPKGSLQDSTLELFANAGFHFSVQSRSYFPSIDDDELEAILIRAQEMARYVSQGAFDAGLTGKDWIIETDSDVVEVADLVYSKASMRPVRWVLAVPESSPIKTVKDLEGKHIATEVVNITKKYLAENGVNASVEFSWGATEVKPPELADAIVEVTETGSSLRANKLRIVETVLESNTKLIANKAAWEDPWKREKIENMAMLLQGAINAQGKVGLKMNAPKAALGAILSGIPALRQPTVSDLTDKEWVALEVIVAEKIVRKLIPELKRAGAEGIFEYNINKLID
>NZ_CP017305.1|WP_069810752.1|2370508_2371240_-|UDP-2,3-diacylglucosamine-diphosphatase
MSALYFVSDLHLGLQEPQAEAEKLERLETLFSTIASTGGSLFLLGDILDYWMEYRHVIPKGFTRFFCMLSGLVRSGVSVTWMAGNHDFYLGSYFDDELGVKTMYGLHEVQHDGCTFLMAHGDGLGDGDLGYKLFARFVRNRFNLGLLTAFHSDLSTALMSWFSRLSRKHKKSDMRAESTRLFDFATSLAQERDFDYFVCGHNHSERIETVHESGSAYVNLGSWIEGRYQYGVYEQGQFRLEQL

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017305_6	6.13|2360667|33|NZ_CP017305|CRISPRCasFinder,CRT	2360667-2360699	33	NZ_CP011275	Planctomyces sp. SH-PL62 plasmid pPL62-2, complete sequence	72106-72138	6	0.818
NZ_CP017305_1	1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT	1045079-1045115	37	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	152793-152829	8	0.784
NZ_CP017305_1	1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT	1045079-1045115	37	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	57358-57394	8	0.784
NZ_CP017305_1	1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT	1045079-1045115	37	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	99923-99959	8	0.784
NZ_CP017305_1	1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT	1045079-1045115	37	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	126556-126592	8	0.784
NZ_CP017305_1	1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT	1045079-1045115	37	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	12202-12238	8	0.784
NZ_CP017305_6	6.13|2360667|33|NZ_CP017305|CRISPRCasFinder,CRT	2360667-2360699	33	NZ_CP034813	Paracoccus sp. Arc7-R13 plasmid unnamed2, complete sequence	185377-185409	8	0.758
NZ_CP017305_6	6.20|2361094|33|NZ_CP017305|CRISPRCasFinder,CRT	2361094-2361126	33	NC_022049	Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence	433435-433467	8	0.758
NZ_CP017305_1	1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT	1045079-1045115	37	MN693075	Marine virus AFVG_25M503, complete genome	10676-10712	9	0.757
NZ_CP017305_1	1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT	1045079-1045115	37	MN693586	Marine virus AFVG_25M48, complete genome	48119-48155	9	0.757
NZ_CP017305_6	6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT	2361155-2361187	33	GU323318	Enterobacteria phage CC31, complete genome	130718-130750	9	0.727
NZ_CP017305_6	6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT	2361155-2361187	33	MN617835	Enterobacter phage prasa_myo, complete genome	140295-140327	9	0.727
NZ_CP017305_6	6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT	2361155-2361187	33	MG999954	Enterobacter phage myPSH1140, complete genome	140295-140327	9	0.727
NZ_CP017305_6	6.13|2360667|33|NZ_CP017305|CRISPRCasFinder,CRT	2360667-2360699	33	NC_006571	Streptomyces albulus plasmid pNO33 DNA, complete sequence	23648-23680	10	0.697
NZ_CP017305_6	6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT	2361155-2361187	33	MN013084	Klebsiella phage vB_KaeM_KaAlpha, complete genome	139413-139445	10	0.697
NZ_CP017305_6	6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT	2361155-2361187	33	KJ101592	Enterobacter phage PG7, complete genome	138304-138336	10	0.697
NZ_CP017305_6	6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT	2361155-2361187	33	LT614807	Cronobacter phage Pet-CM3-4 genome assembly, chromosome: I	136887-136919	10	0.697
NZ_CP017305_6	6.39|2362254|33|NZ_CP017305|CRISPRCasFinder,CRT	2362254-2362286	33	NC_008043	Ruegeria sp. TM1040 megaplasmid, complete sequence	683660-683692	11	0.667

1. spacer 6.13|2360667|33|NZ_CP017305|CRISPRCasFinder,CRT matches to NZ_CP011275 (Planctomyces sp. SH-PL62 plasmid pPL62-2, complete sequence) position: , mismatch: 6, identity: 0.818

tttccggcatctcgtccgcgacgagcgccagct	CRISPR spacer
aatccggcatctcgtccgcgacgagcctccact	Protospacer
  ************************ .* .**

2. spacer 1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 8, identity: 0.784

ttcagagataataaatatctttttaaacattatactt-	CRISPR spacer
caaatagataaacaatatctttttaaacatt-tactaa	Protospacer
.  * ******  ****************** ****  

3. spacer 1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 8, identity: 0.784

ttcagagataataaatatctttttaaacattatactt-	CRISPR spacer
caaatagataaacaatatctttttaaacatt-tactaa	Protospacer
.  * ******  ****************** ****  

4. spacer 1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 8, identity: 0.784

ttcagagataataaatatctttttaaacattatactt-	CRISPR spacer
caaatagataaacaatatctttttaaacatt-tactaa	Protospacer
.  * ******  ****************** ****  

5. spacer 1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 8, identity: 0.784

ttcagagataataaatatctttttaaacattatactt-	CRISPR spacer
caaatagataaacaatatctttttaaacatt-tactaa	Protospacer
.  * ******  ****************** ****  

6. spacer 1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 8, identity: 0.784

ttcagagataataaatatctttttaaacattatactt-	CRISPR spacer
caaatagataaacaatatctttttaaacatt-tactaa	Protospacer
.  * ******  ****************** ****  

7. spacer 6.13|2360667|33|NZ_CP017305|CRISPRCasFinder,CRT matches to NZ_CP034813 (Paracoccus sp. Arc7-R13 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

tttccggcatctcgtccgcgacgagcgccagct	CRISPR spacer
cggtcagcatctcggccgcgacgatcgccagcc	Protospacer
.  .*.******** ********* *******.

8. spacer 6.20|2361094|33|NZ_CP017305|CRISPRCasFinder,CRT matches to NC_022049 (Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence) position: , mismatch: 8, identity: 0.758

ccccgcgctgggcggggctggtgggctgattgc	CRISPR spacer
gaccggcgggggcggggcgggcgggctgattgc	Protospacer
  ***    ********* **.***********

9. spacer 1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT matches to MN693075 (Marine virus AFVG_25M503, complete genome) position: , mismatch: 9, identity: 0.757

ttcagagataataaatatctttttaaacattatactt	CRISPR spacer
tttgtagataataaatatctttctaaaaattctgcag	Protospacer
**.. *****************.**** *** *.*  

10. spacer 1.5|1045079|37|NZ_CP017305|CRISPRCasFinder,CRT matches to MN693586 (Marine virus AFVG_25M48, complete genome) position: , mismatch: 9, identity: 0.757

ttcagagataataaatatctttttaaacattatactt	CRISPR spacer
tttgtagataataaatatctttctaaaaattctgcag	Protospacer
**.. *****************.**** *** *.*  

11. spacer 6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT matches to GU323318 (Enterobacteria phage CC31, complete genome) position: , mismatch: 9, identity: 0.727

ttcttcagagccagaagatttctgcttctacga	CRISPR spacer
caatatcgcgccagaagatttcttcttttacga	Protospacer
.  * . * ************** ***.*****

12. spacer 6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT matches to MN617835 (Enterobacter phage prasa_myo, complete genome) position: , mismatch: 9, identity: 0.727

ttcttcagagccagaagatttctgcttctacga	CRISPR spacer
caatatcgcgccagaagatttcttcttttacga	Protospacer
.  * . * ************** ***.*****

13. spacer 6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT matches to MG999954 (Enterobacter phage myPSH1140, complete genome) position: , mismatch: 9, identity: 0.727

ttcttcagagccagaagatttctgcttctacga	CRISPR spacer
caatatcgcgccagaagatttcttcttttacga	Protospacer
.  * . * ************** ***.*****

14. spacer 6.13|2360667|33|NZ_CP017305|CRISPRCasFinder,CRT matches to NC_006571 (Streptomyces albulus plasmid pNO33 DNA, complete sequence) position: , mismatch: 10, identity: 0.697

tttccggcatctcgtccgcgacgagcgccagct	CRISPR spacer
gtggtggcagctcgaccgcgacgagcgccgaag	Protospacer
 *  .**** **** **************..  

15. spacer 6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT matches to MN013084 (Klebsiella phage vB_KaeM_KaAlpha, complete genome) position: , mismatch: 10, identity: 0.697

ttcttcagagccagaagatttctgcttctacga	CRISPR spacer
caatatcacgccagaagatttcttcttttacga	Protospacer
.  * . . ************** ***.*****

16. spacer 6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT matches to KJ101592 (Enterobacter phage PG7, complete genome) position: , mismatch: 10, identity: 0.697

ttcttcagagccagaagatttctgcttctacga	CRISPR spacer
caatatcacgccagaagatttcttcttttacga	Protospacer
.  * . . ************** ***.*****

17. spacer 6.21|2361155|33|NZ_CP017305|CRISPRCasFinder,CRT matches to LT614807 (Cronobacter phage Pet-CM3-4 genome assembly, chromosome: I) position: , mismatch: 10, identity: 0.697

ttcttcagagccagaagatttctgcttctacga	CRISPR spacer
caatatcacgccagaagatttcttcttttacga	Protospacer
.  * . . ************** ***.*****

18. spacer 6.39|2362254|33|NZ_CP017305|CRISPRCasFinder,CRT matches to NC_008043 (Ruegeria sp. TM1040 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.667

ttttatttcagtcaccagcaccggctccgtctc	CRISPR spacer
cagacgatcagtctccagcaccggcgccgtcat	Protospacer
.      ****** *********** ***** .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	326526 : 335346	7	Enterobacteria_phage(33.33%)	tRNA	NA
DBSCAN-SWA_2	1893226 : 1954285	59	Staphylococcus_phage(40.0%)	tRNA,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP017305|326526:335346|DBSCAN-SWA
CATGAAAGGCATCATTCTTGCCGGCGGATCAGGTACCCGCCTCTATCCGGTGACCAGGGGTGTATCGAAGCAGCTCCTGCCGGTGTACGACAAGCCGATGATCTACTATCCTCTCTCCACGCTGATGCTTGCGGGCATCAGGGATATTCTGGTCATCACCACGCCCGAGGATCAGCCGTCGTTCGTCAAGCTGCTCGGCGATGGCAGCGACTGGGGCATCTCGATTTCCTATACCGTCCAGCCACGCCCGGACGGTCTGGCGCAGGCCTTCATTCTCGGACGCGAATTTATCGGCGACGACGACGTTTGCCTCGTGCTTGGGGATAATATCTTTTTTGGTTACGGCTTCAGCGGAATGCTCGAAGAGGCGGTTCGAACCGTGCAAACCCGCAGAAATGCGGTCGTCTTCGGCTACTATGTCAGTGATCCGGAGCGGTACGGCGTGGTCGAGTTCGATCCGGAAGGGCAGGTGCTCTCCATCGTCGAGAAGCCTGAAAAGCCGAAATCGAACTACGCCGTCGTGGGCCTTTACTTTTATACGAACGATGTGGTTGATATTGCCGCTGGTATCACTCCGTCGGCCAGAGGAGAGCTGGAGATCACCTCGGTGAACCAGACGTACCTTGAACGCGGCGATCTGGTTTGTTCCATCTTGGGGCGCGGATTTGCTTGGCTCGACACCGGTACCCATGAATCATTCCAGGAAGCGGGAAGCTTCATTGAAACAGTCGAAAAGCGGCAGGGCCTCAAGATTGCCTGTCCCGAAGAGATTGCCTGGCGAAACGGCTGGATTGGCGATGCTGAACTGGAACGTCTCTCAACGCCACTTCTCAAGAACCAGTACGGGCAGTATCTGCTCAAGCTTCTGGAACGGAGAATCTGAGCCGGGCGATTGCATGTTTATCAATTCATCAGCCCCAGATTAATTTATGCAGATGATCCAGACCTCGATTCCTGACGTGCTGTTGTTCGAGCCAAAAGTGTTCGGCGACGAGCGCGGCTGGTTTTTCGAGTCTTTCCGGCAGGATATTTTCGAGCAGTACGCCGGATGCCACCGTTTCGTGCAGGATAATGAAGCGTTTTCCCGTTACGGAGTGCTTCGCGGGCTGCACTACCAGAAACCGCCTTATACGCAGGGCAAGCTTGTTCGCGTTATCCAGGGCAGCGTGCTCGACGTGGCGGTCGATGTACGCAAGGGATCGCCGACCTTCGGCCAGTATACGGCCCAACTGCTCAGCGACCAGAACCACCGCATAATGTGGGTTCCGCGTGGATTCGCGCATGGCTATGCGGTGCTGAGCGAGACGGCGATTTTCAGTTACAAGTGCGATAACTACTACGCGCCGTCACACGATGCAGGAATCAGGTGGAACGATCCGGCGCTCGGCATCGATTGGCGATTGCCCGAGAGCGACGTGAGTCTGTCGGACAAGGATCAGCGTCAGCCGATGTTTCATGAAATCGATCCGGTTGTGCTGACGTCATAGTCTCTTTTTTGTTTTGCGAATCTACGTGATACCCTCAATGAATATTCTTGTCACCGGGAGCCATGGGCAGCTTGGCTCCGAATTGCGCAAACACCAGGAGATACAGGGGCGGCAGGGATGGTTTTTCGCCGATATCCCTGACCTCGATATTACCGATGCGTCCGCCGTGGAGCGTGTTTGCCGCGACCGGCAGATCGGCGCGATGGTCAACTGCGCGGCTTACACAGCGGTGGACAAGGCCGAGAGTGACATCGATGCGGCCTTCAGGGTGAACCGCGACGGCGCGGCGGTGCTCGCTTCGGTCGCAAAAGCGGCAGGCGCGCTGCTCCTGCACGTTTCGACCGACTACGTTTTCGACGGATCGAGCAACCGACCCTATCGCGAAGATGATCCGGCAACTCCTCTCGGGGTGTATGGTCAGTCCAAGTGGGAGGGGGAGGAGGCGATCCGCTCAATCGGCTGCTCGCATCTCATCGTTCGCACCTCATGGCTCTACTCGGCTTACGGGCAGAACTTCGTGAAGACGATGCTTCGCCTTGGCCGGGAGCGTGAGTCGATTGGGGTGGTGTTCGATCAGGTTGGTACGCCAACCTGGGCCGCCGACCTGGCTGGAGCCATCGTGTCGATGCTCGACCGGCTCGATCCGGCGCGGAGTTATGCCGAAACTTTTCACTACTCGAACGAAGGGGTCTGCTCATGGTACGATGTCGCCACGGAGGTGATGAATGCCGCCGGACTATCGTGCCGTGTCATGCCGATCGAGAGCCACGAGTACCCGACGCCGGTGACACGCCCGCCCTACAGTGTGCTGAACAAGCGCAAGATCAAAAATGCCTGGGGTCTCGAAATTCTCCACTGGCGCCAGAGCCTGCTGAAGATGCTCGAAGAGTTGCGGGAGGGCGGCGGTAACTCGTGACGCTGGGTGTCATGGGACTCATGGGACTTGTGGGTCGGGAAGATGGATGCGGATTTTTCTGATTTCCAATTCATAATTCATAATTTGTTCAATGCATATACTCATAACCGGCGGGGCGGGGTTTATCGGTTCGCATGTGGTCAGGCATTTTCTGGAGCGCTATCCCGGCTACGCCATCACCAATCTCGACAAGCTCACCTACGCGGGCAACCTGGCCAATCTGCGCGATGTCGAGTCGAACCAGAACTACCGGTTCGTGAAGGGCGACATTGCCGATGGCGCGTTCCTGCTCGATCTGTTCAGGGAGCAAACGTTCGATGCGGTCATTCATCTTGCCGCGGAGTCGCACGTTGACCGCTCCATCGAGAGCCCGGTCGAGTTCGTGGTCTCCAACGTGCTCGGCACGGTCAACCTGCTCAATGCGGCGAGGGCGACGTGGGATGGCGCGTTCGAGGGCAAACGCTTCTACCATATCTCGACCGACGAGGTGTACGGTTCGCTCGGCAGCGAGGGGATGTTTACCGAGGCCACGCCCTACGATCCGCACAGCCCCTATTCGGCCTCGAAAGCCTCTTCCGACCACTTTGTCCGCGCATTCCACGACACCTACGGCCTGCCGGTGGTGATCAGCAACTGCTCGAACAACTACGGCTCGCACCAGTTTCCCGAAAAGCTGATCCCGCTGTTCATCAACAACATCCGTCTGCGGAAGCCGCTGCCGGTCTACGGCGCGGGGCTGAACATTCGGGACTGGCTCTGGGTGGTCGATCACGCCCGCGCCATCGACGAAATCTTCCATCGCGGAACGGCGGGCGAGACCTACAATATCGGCGGGCACAACGAGTGGACGAACATCGATCTCATCCGTTTGCTCTGCCGCATCATGGACAGGAAGCTCGGCAGGGAAGCGGGGGAGTCGGAAACGCTCATCACCTACGTCACCGACCGTGCGGGCCACGATCTCCGGTACGCCATCGACGCCTCGAAGCTGCAACGCGAGCTTGGCTGGGTGCCCTCCGTCACCTTCGAGGAGGGTTTGGAAAAGACGGTCGATTGGTATCTTTCCAATCAGCCATGGCTCGACGAGGTAACATCGGGGGCCTATCAGCACTATTATGAAAAGATGTACGCAGGGCGCTGAGAGCCAGTTTCCTTGCATGAAAATAACCACTTGTACGTTTTGAGTCGATGATCATACCCGTCATTCTGAGCGGAGGTTCGGGAACCCGTCTCTGGCCATTGTCGAGAGCCATGTATCCCAAACAGCTTCTGCCCCTTTTCGGACAGTACACAATGTTTCAGGATACGGTGCAACGTGTTTCGGCAGTGGCGGAAACAGGCCCAATCATTTGCGTCTGCAACGATGACCACCGGTTTCTCGTGGCCGAACAGCTCCGGCAGATCGATGCGGAAGGCGCCATCATTCTCGAACCTTTCGGTCGCAATACCGCGCCAGCCGCCGCTATTGCGGCTCTGATCATTGCCGCGAGCCAACCCGGCGCGCTCATGATGCTCCTGCCAGCCGATCATCTCATACTCGACCGTGAAGCCTTTGCCGCATCGATCGAAATGGCTCGGAGCGCGGCGGCGGAAGGGCGTCTGGTAACCTTCGGCATTGTTCCGTCCGCCCCTGAAACGAGGTATGGTTATATCAGGGCGGTTGCCGGTTCCAGTGGCGTGGCCCGCCCTGTCGCCGAATTCGTCGAGAAGCCCTCGCTCGAACGGGCGGAAAGCTACGTGGCGTCGGGCGACTATTTCTGGAACAGCGGGATGTTTCTGTTCAAGCCCGAGGTCTATCTCGCCGAACTCGAAGCGAACTCGCCCGAGATTCTCGATGCATGCCGGAACGCTATGCAAAAAGCCCGGCGCGATCTCGATTTCCTGCGGCTTGACCCAGAAGCCTTCGCGGCCTGCCCTTCCGATTCGATCGACTATGCGGTTATGGAAAAAACTTCCAACGCAGTAGTGGTGCCCATGCAGGCGGGGTGGAACGATGTCGGCGCGTGGTCGGCGCTGTGGGGTGTGCATGAGCGCGACGCCGAGGGCAACGTCAAGCATGGCGACGTGCTGACGCACGGAGTGAGGAACAGCTACATCCACGCCACCAGCCGACTCGTAGCGGCCGTTGGTCTGGACGATCACGTGATTGTCGAGACTGCCGACGCGGTGCTTGTCGCCTCGAAAGATCGGGTACAGGAGGTCAAGGCGATTGTCGAGCAGCTCCGGTTGCAAAAGCGCCAGGAGCCGCTGATTCACCGGCGGGTCTACCGCCCTTGGGGTTCGTACGAAACCGTCGATGAGGGGGAGCGCTTCAAGGTCAAGCGCATTACGGTCAAACCCGGTGCGGCGCTCTCCCTGCAGATGCACCATAAGCGCGCGGAGCACTGGATCGTGGTGACCGGCAGGGCGATGGTGACGGTTGGAGAGCGGCAAGTTCCGCTCGAGGCGAACGAGTCGATCTACATTCCGGTCGAAGAGAAACACCGGCTCGAAAATCGCGGCGACGCGCCGCTCGAACTCATCGAAGTGCAGTCAGGCGAATACCTCGGCGAGGACGACATCGTGCGATTCGAAGACCACTATGGGCGATTGTGAAGCAGCGGATGGAGTTGCCTTTTCGCTCTTTCTTCTCTTATAGGACTTATAGGTCTTATAGGGCCGGAAAACCGCGCTCGTCTTGTATCGGATAGATTATTGTGATACATTGACCTGTTGCGATATTGCGGCATTACAGACGATTCAAATCCAAATTCCGGTAGCATATGGCTGAAGATATGAGAACTCCCAACCAGGGACAGCAGGTCGGTGACGTCGTGAAAGGTGATTTCGCGACCATTCTCGTTGGTTTGGGCACAATGCTCGACGGAGCACTGACGCCTCTGAGCAAGGTCGTGGCCTCGGCGCTCGATTCGATGACGGTCGTGGCCAAACAGATTCTCGACGGCATCAACAACTCTGCTGCCGGTAACAGACAGCAGTGACCAATCGCTGATGGCTGCGTCGCCGGGACTTTCCTGTGTGCCGCATCTGAAGGCAGCCTGATTCAGCACCATCGGGCTGCCTTTCTCTTTTCCTGCCGATTCTCGTATATTCAGACTTTTCCGCGAAGCGGGGCCGGTTCCCGCCTCCGCAATGATATTTCCAGCTTGACATTCTGACCATCATGCCCGACACCTATCCCGAGTATCCGTCCTCTCTTACATACAGCGCCATGGAGGCCCGCGTTCGCCAGTTCTGGGACGAACAGGGCATTTTTCGCAAAAGCCTCGAAAAGGATGCCCCGAAAGGCATCTACTCGTTTTATGAAGGGCCGCCGACGGTCAATGGCAAGCCGGGCGTGCATCACGTTTTCAGCCGCACCATCAAGGATGTGGTCTGCCGCTACCACGCCATGCAGGGTTTCGAGGTGCCGCGCAAGGCTGGCTGGGACACGCATGGTTTGCCTGTCGAGATTTCGGTCGAAAAGAAGCTTGGCCTGAAGAACAAGTCGCATGTCGAGGAGTACGGCGTTGGCGAGTTCAACCGCGAGGCGCGCTCGCTGGTCTATCACCACATCGACGACAACCGCGAGGGGTGGGGCAGGCTTACCGAGCGCATGGGCTACTGGGTCGATATGGACAGTCCCTACATCACCTGCGACAACAACTACATCGAGTCGGTCTGGTGGGCGCTGAAGACCATCTTCGACAAGGGGCTGATCTACAAGGATTACAAGATTGTGCCGCAGGATCCGAAGTCCGAGACGGTGCTCAGCTCGCACGAACTGGCGCTTGGCTACAAGGAGGTGCAGGATCCGAGCGTCTACGTGAAGTTCCGCCTGAAGGATTCGGAGGAGAGCATTCTCGTCTGGACGACCACGCCCTGGACGCTCATCTCGAACGTCGCTCTCGCTGTGGGCCGCGACATCGACTACGTGCGCGTCCGCAATCGCGAAACCGGCGAGGTGCTGATTCTGGCTGAATCGCGCTTGTCGGTGCTCGTCGAGAAGATCGGCGAGGAGTCGGCATGGGAGGTGATCAGCCGCTGCAAGGGCAGCGAACTCGAAGGGCGCGACTACGAGCCGCTTTTCAACTACTTCGCGCCCGAGCGCCGCGCCTGGTATGTGGCCTGCGGTGAGTTCGTCTCGACCGGCGATGGCACGGGCATCGTGCACATCGCACCGGCCTTCGGCGCGGACGACTACGAGCTGTCGAAGCAGTACCAGCTTCCGATGCTTCAGCCGGTGGCCCGCAACGGCTGCTTCACCGCCGAGGTGCCAGACTACGCCGGTATGTTCTTCAAGGATGCCGACAAGCCGATCATGCAGCGCCTGAAGGAGGAGGGCAAGCTCTATCGCCGCGAGACGATCCAGCACACCTACCCCTTTTCGTGGCGCTACGACGTGCCGGTGATCTACTACGCCCGCGAGTCGTGGTACATCCGCACCACCGACATCGCGCCGCGCATGGTGGAGCTGAACAAGACGATCAACTGGAATCCCTTCGAGATCGGCGCGGGACGCTTCGGTAACTGGCTCGAAGAGAACAAGGACTGGGCGCTCTCCCGCGAGCGCTTTTGGGGCACGCCGCTGCCGGTGTGGGTCGCTGAAGATTTCGCCATCGGCGACGGCCCCGCCTCCGGTAAGCTTTTCGCCGTCGGCTCGGTCGCGGAGCTGCGCGAGGGCTTCATCGAGATCGATGGCGAGCAGATGAATCTCGGCGAGGCGCTCGACAAAGCTCTCGTGGAACTCGACCTGCACAAGCCCTTCGTGGATCGCATTTATTTCATCCGCGACGGCAAGCGCTTCAACCGCACGCCGGAGCTGATCGACGTCTGGTTTGACAGCGGCTCGATGCCCTTCGCCCAGCTCCACTATCCCTTCGAGAACAAGGAGCTGTTCGAAAAGACCTTCCCGGCGGACTTCATCGCCGAGGGGGTTGACCAGACGCGCGGCTGGTTCTACACGCTCCACGCCATCGCGACGCTCATCTTCGACCGCCCGGCCTACCGGAACCTGGTCGTCAACGGCCACATCCTCGACAAGAATGGGCAGAAGATGTCCAAATCGAAGGGCAACGTGGTCGATCCGTTCGAGTCGATGGAGAAGTACGGCGCGGACGCCATCCGCTGGTACCTCATGATCACCAGCCCGCCGTGGCGCCCGAAGCTCTTCAACGCCGACGAGATCGAGGAGGAGCAGCGCAAGTTCTTCCGCGCCTTCATCAATAGCTACAACTTCTTCGTGCTTTACGCGAACGTGGACGGTTTCCGCAACCAGGAGGCTGACATTCCCTTCGCCGAGCGCTCGGAGCTTGACCGCTGGATTCTCTCCAGCCTCAACACGCTCATCGCCGAAGTGACCCGCCGCATGGAGGGCTACGACCTCACCGGCGCGTGCCGTCTCATCGGCGACTTCACCGTGGACGACCTCTCGAACTGGTACATCCGCCGCTCGCGCAAACGCTTCTGGAAAGGGGAGATGGGGCCGGACAAACTCTCGGCTTACCAGACGCTCTCGACGGTGCTCGAAACGCTCTCGAAGCTGCTTGCGCCTTTCGCGCCCTTCATCGCCGAAAAAATGTGGCTCGACCTGACCGGCGTCAGCGCGAAGGGGCAGGCCGAATCGGTGCACCTCGCCGACTGGCCGGTGGCCGACGAAAGCTGCATCGACGCGGCGCTCGAAGAGCGGATGAAGAAGGCGCAGATCGTCACGTCACTCGTGCGCACCATGCGCGAGAAGGCCACCATCAAGGTGCGCCAGCCGCTCCGGCGTATCCTGCTCGCCGCCGCCGAACCCGGTTCCCGCGCCGCCTACGAACTGGTTTCGGAGATCATCCGTGAGGAGGTCAACGTCCAGAAGATCGAGTATGTCGAGGACGAGGATGGTTCGGTGATCAGCAAAAAGGCCAAGCCGAACTTCAAGGCGCTCGGCCCGCGCTTCGGCAAGGATATGAAGGCGCTCGCCGAAGAGATCAGGATCATGAGCCACAAGCAGATTTCGCGCCTCGAAACGGAAGGCTCCATCGAGATTGATCTCGGCGGACGCATTTGCACCGTGCTTCGAGAGGATGTTGACATCGTGCACGAGGATATCGAGGGGTGGCTCGTGGCGGCGGACGACGCGCACCGCATCATGGTGGCGCTCGACACCGAGATCACCGAGGAGCTTGAGATGCTCGGCCTGGCCCGCGAGCTGGTCAGCAAGATTCAGACCCTCCGCAAGGAGAGCGGCCTCGACATCACCGACCGCATCACGCTGAAGGTCGAGGGCAGTGAAAAGCTGCTGAAGGCAGCGAGGGCCAGCGAATCCTACATCAAGGATGAGACGCTCGCCACGGCGATGGTGCTGCTGCCGCTCGAAGGCTCGCCGTCAGCCGACGAAGCCGAGCAGGTCAACAATGAATTGTGCCGGTTGTCGCTTGAAAAATCCGCTTCATGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP017305|326526:335346|328049_328928_+|WP_069808655.1|DBSCAN-SWA
MNILVTGSHGQLGSELRKHQEIQGRQGWFFADIPDLDITDASAVERVCRDRQIGAMVNCAAYTAVDKAESDIDAAFRVNRDGAAVLASVAKAAGALLLHVSTDYVFDGSSNRPYREDDPATPLGVYGQSKWEGEEAIRSIGCSHLIVRTSWLYSAYGQNFVKTMLRLGRERESIGVVFDQVGTPTWAADLAGAIVSMLDRLDPARSYAETFHYSNEGVCSWYDVATEVMNAAGLSCRVMPIESHEYPTPVTRPPYSVLNKRKIKNAWGLEILHWRQSLLKMLEELREGGGNS
>NZ_CP017305|326526:335346|327454_328012_+|WP_069808654.1|DBSCAN-SWA
MQMIQTSIPDVLLFEPKVFGDERGWFFESFRQDIFEQYAGCHRFVQDNEAFSRYGVLRGLHYQKPPYTQGKLVRVIQGSVLDVAVDVRKGSPTFGQYTAQLLSDQNHRIMWVPRGFAHGYAVLSETAIFSYKCDNYYAPSHDAGIRWNDPALGIDWRLPESDVSLSDKDQRQPMFHEIDPVVLTS
>NZ_CP017305|326526:335346|329019_330069_+|WP_069808656.1|DBSCAN-SWA
MHILITGGAGFIGSHVVRHFLERYPGYAITNLDKLTYAGNLANLRDVESNQNYRFVKGDIADGAFLLDLFREQTFDAVIHLAAESHVDRSIESPVEFVVSNVLGTVNLLNAARATWDGAFEGKRFYHISTDEVYGSLGSEGMFTEATPYDPHSPYSASKASSDHFVRAFHDTYGLPVVISNCSNNYGSHQFPEKLIPLFINNIRLRKPLPVYGAGLNIRDWLWVVDHARAIDEIFHRGTAGETYNIGGHNEWTNIDLIRLLCRIMDRKLGREAGESETLITYVTDRAGHDLRYAIDASKLQRELGWVPSVTFEEGLEKTVDWYLSNQPWLDEVTSGAYQHYYEKMYAGR
>NZ_CP017305|326526:335346|331690_331909_+|WP_069808658.1|DBSCAN-SWA
MAEDMRTPNQGQQVGDVVKGDFATILVGLGTMLDGALTPLSKVVASALDSMTVVAKQILDGINNSAAGNRQQ
>NZ_CP017305|326526:335346|330116_331523_+|WP_069808657.1|DBSCAN-SWA
MIIPVILSGGSGTRLWPLSRAMYPKQLLPLFGQYTMFQDTVQRVSAVAETGPIICVCNDDHRFLVAEQLRQIDAEGAIILEPFGRNTAPAAAIAALIIAASQPGALMMLLPADHLILDREAFAASIEMARSAAAEGRLVTFGIVPSAPETRYGYIRAVAGSSGVARPVAEFVEKPSLERAESYVASGDYFWNSGMFLFKPEVYLAELEANSPEILDACRNAMQKARRDLDFLRLDPEAFAACPSDSIDYAVMEKTSNAVVVPMQAGWNDVGAWSALWGVHERDAEGNVKHGDVLTHGVRNSYIHATSRLVAAVGLDDHVIVETADAVLVASKDRVQEVKAIVEQLRLQKRQEPLIHRRVYRPWGSYETVDEGERFKVKRITVKPGAALSLQMHHKRAEHWIVVTGRAMVTVGERQVPLEANESIYIPVEEKHRLENRGDAPLELIEVQSGEYLGEDDIVRFEDHYGRL
>NZ_CP017305|326526:335346|326526_327408_+|WP_069808653.1|DBSCAN-SWA
MKGIILAGGSGTRLYPVTRGVSKQLLPVYDKPMIYYPLSTLMLAGIRDILVITTPEDQPSFVKLLGDGSDWGISISYTVQPRPDGLAQAFILGREFIGDDDVCLVLGDNIFFGYGFSGMLEEAVRTVQTRRNAVVFGYYVSDPERYGVVEFDPEGQVLSIVEKPEKPKSNYAVVGLYFYTNDVVDIAAGITPSARGELEITSVNQTYLERGDLVCSILGRGFAWLDTGTHESFQEAGSFIETVEKRQGLKIACPEEIAWRNGWIGDAELERLSTPLLKNQYGQYLLKLLERRI
>NZ_CP017305|326526:335346|332091_335346_+|WP_069808659.1|tRNA|DBSCAN-SWA
MPDTYPEYPSSLTYSAMEARVRQFWDEQGIFRKSLEKDAPKGIYSFYEGPPTVNGKPGVHHVFSRTIKDVVCRYHAMQGFEVPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFNREARSLVYHHIDDNREGWGRLTERMGYWVDMDSPYITCDNNYIESVWWALKTIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYKEVQDPSVYVKFRLKDSEESILVWTTTPWTLISNVALAVGRDIDYVRVRNRETGEVLILAESRLSVLVEKIGEESAWEVISRCKGSELEGRDYEPLFNYFAPERRAWYVACGEFVSTGDGTGIVHIAPAFGADDYELSKQYQLPMLQPVARNGCFTAEVPDYAGMFFKDADKPIMQRLKEEGKLYRRETIQHTYPFSWRYDVPVIYYARESWYIRTTDIAPRMVELNKTINWNPFEIGAGRFGNWLEENKDWALSRERFWGTPLPVWVAEDFAIGDGPASGKLFAVGSVAELREGFIEIDGEQMNLGEALDKALVELDLHKPFVDRIYFIRDGKRFNRTPELIDVWFDSGSMPFAQLHYPFENKELFEKTFPADFIAEGVDQTRGWFYTLHAIATLIFDRPAYRNLVVNGHILDKNGQKMSKSKGNVVDPFESMEKYGADAIRWYLMITSPPWRPKLFNADEIEEEQRKFFRAFINSYNFFVLYANVDGFRNQEADIPFAERSELDRWILSSLNTLIAEVTRRMEGYDLTGACRLIGDFTVDDLSNWYIRRSRKRFWKGEMGPDKLSAYQTLSTVLETLSKLLAPFAPFIAEKMWLDLTGVSAKGQAESVHLADWPVADESCIDAALEERMKKAQIVTSLVRTMREKATIKVRQPLRRILLAAAEPGSRAAYELVSEIIREEVNVQKIEYVEDEDGSVISKKAKPNFKALGPRFGKDMKALAEEIRIMSHKQISRLETEGSIEIDLGGRICTVLREDVDIVHEDIEGWLVAADDAHRIMVALDTEITEELEMLGLARELVSKIQTLRKESGLDITDRITLKVEGSEKLLKAARASESYIKDETLATAMVLLPLEGSPSADEAEQVNNELCRLSLEKSAS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069808653.1|326526_327408_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	4.8e-105	62.5
WP_069808654.1|327454_328012_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	2.4e-46	51.4
WP_069808655.1|328049_328928_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.3e-35	38.2
WP_069808656.1|329019_330069_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.0e-86	50.8
WP_069808657.1|330116_331523_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	8.8e-53	29.3
WP_069808658.1|331690_331909_+	hypothetical protein	NA	NA	NA	NA
WP_069808659.1|332091_335346_+|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	1.6e-166	34.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP017305|1893226:1954285|DBSCAN-SWA
GTCAACCGGTAATAGCCATGTTGAGCTTTCCACAGTAAAACAAAATCCTTATGCGGTAGCTGTGAAAGCTGTGGAACCCACGAGCCGATGCTTTGTACAACTGGATCTTGCTGTTCAGACCTTCGGAAACTGCGTTGGTCATTTCGTGCTCGAAATAGTTCAGGATGTTGTCGAGATGCCGCTTCAGCAGCTCTTTGACCTTGATCATGGGTTTCAACGCTAACTGGTCAACGCGTTCAGACCAGTAATCGAAAAAGAAGCTTGCACTCTCTCGACAACCCAGCCGCCAGAACTCCCGAAACATGTTCTTCATCGACCAGGCTTTTCCGGTTTTCAGCTCACAGGCCATCAATTGATCAAAGCTTGTCCGCTGGCTTTCCGTCATGTTCTCCGGATTGCGCAGCCAGGTGAATTTCGAGCCAATCAGAGTCCTGTCCCCTGCATGATGAAGTTGACGGGACTCTTGGCGACGAACCGTGTCGACCGCCTCGTTCAGATATTTGCTGATATGGAAACGGTCATGCACAATATCGGCCTGCGGCAGATGCTTTTTGGCAGCAATCGCGAAGGGTTTCCACATATCCATCGAGATCGATTTCACACCCTGGCGTTGCGATGCTTCAAAGCTGAGGAGTAGCGCTTCTGCTCCATCGGTCGTTCGGCTCTGGACCACCTCAAGTACCCGGCCACCTTTCAGGTCGTTCAGGATCGTCACATACTGATGGCCTGCCCGGAAGCTCTTTTCATCAAGACCAAGATGAGCAATCGCCTCCTTATTCCGGCGGCTCAGGCCTCGCTTAACCGCACGGTTCATGATCTCGTTGGTTGCATGCCAGTTCAATCGCAAGAGCCTCGATGCCGACTGAATGCTTGAACACTCCTGAAGCAACTCGACAGCAAGCGCTTCAAACTTCAGGGTGTAGCGCGAATAGCGCGTTGCCCACGGAACTTGAATTGTCTTGATCCTGTGCTCTTTGCACTCACACCGAGGCACCCTGGCTATCAGATGCGTCTCATACTCCATGGTATCCAGATGCCGCCACCGTTGTTCTGGCGCCAGGTCATAAATTCGTCCGGCCTTGCCGCATTCAGGGCATTCGACTTTGGGTCCGATATACTCCAGATGGATTTCTATCCGGGGGCCGGACATCGACAGCCGGACATCCGACACCTTCCATGTTTCTGGTAATCCTAATAACTGCTGGTAATGGGCAATGAGGCTCGGCATACGTTGGGGTTAGTGTTTTGGCGTTCTTGGATAAATTACACCAAGCCACTCATTTTTACTACCAGCCCATTAAATTCTGCGAAGAGCCGAAAGCAAAGAGAAATCATTATAAACACCTCGAAGCTCTGCTGCGCAACAGTTGAGTCATGACGAAATCATCGAAGAGTGCCCGATCTTGAAAAAGAGGACAATCTGGCAGCTCTCAAATATGCCAGCCAAAAGCTTGACCATCCGGTGATCGCGGCATGACCATCTGGATCGATGCACACCTGTCGCCTTGACTTGCAGCTTGGAGCAACCGCACGTTTACGGGCATCGAGGCAAAATCGCTGAGCAGTCTCGGTTTACAATGAGACGATGACAAGACCATTTTCGAGGCAGTCCGAAAAGCCGGTGCCGTTATGATGAGCAAAGATTCGGATTTCCTTCAATTCGTCGATCAACTCGGTGTACCGCCTCAAATCCTCTGGATTACCTGTGGCAACACGTCGAATACCAGAGTGAGAGAAGTGCTTGAAAAATCCTTTGGCAAGGCTGTCGAACGGCTTCGCAATAGTGAGCCTGTCGTTGAAATCAGTGATCTGCATTAAGTTATCTTCCCGACCGGTCATCTTCTGCACTTCCCCCAACTCTCCCCCGATTTTCGTACTTTCGAGTATAGCATGTTGGTCTAACCTGTTTTGCAGCTTATGAAAATCGGAATCTCCTGTCATCATACCTACGGCGGAAGCGGGGCGGTGGCTACCGAGTTGGGGAAGGCGCTCGCCATGAAGGGCCACACGGTGCACTTTTTCAGTCAGGCGGCTCCGTTTCGGCTTGGCCTCTATTCGCGCAACATCCATTGCCACGAGATCGAGGCGATGAACTATCCGCTCTTCGAGACGCCGTACCACTCGCTGGCGCTGGCCTCGAAGATCGCCGAAGTGGCGTATTATGAAAAGCTCGACGTCGTCCACGCCCATTACGCCATTCCTCACGCCATCAGCGCCATGCTGGCCCGCCAGATGCTCGAAGAGAAGTGCCCCGCTGCGGAGTGCTTCCGGATTGTCACAACGCTGCACGGCACCGACATCACCATCGTCGGGGCCGACAGGAGCATGAGTGACGCCGTGCGGCTCGCCATCAACAAGTCGGATGGCGTGACGACGGTTTCTGGCTACCTTCGGGACGAGACCATCCGCATGTTCACGCCCCGCAAGAAGATCGAGGTGATTCACAATTTCGTCGATACCTCCGTCTTCCAGCGCCTGCCCGGACGGCGGGAACTCCTCGGCATCGACGAGGGCAAGGTGGTGATTCACATCTCGAACTTCCGGCCTGTCAAGCGTATCATGGATGTGCTGGCGGTGTTCGAGCGCGTCCGGCGCGAGATTCCGGCCACGCTGCTGCTGGTGGGCGACGGGCCGGATCGCAGCGAAGCGGAGACCTGGGTGCGGCAGCAGGGTATTGGCGAAAGCGTGCGCTTCCTCGGCAAGCTCAACGACATCGTGCCGCTGCTCTCCATCGCCGACCTGATGCTCATGCCGAGCAACGTCGAGTCGTTCGGCCTGGCTGCGCTCGAAGCGATGGCCTGCGGTGTACCGGTGGTCGTGACCGACGCGGGCGGATTTCCGGAATTCGTGCGGCAGGGGGTGGACGGTTTCCGCCATCCGCACGGCGACATTGAGGGGATGAGCCGCAGCGCGCTCTCGATTTTGCAGGACGAAGCGGTGTGGCAGCGCTTTTCGGAGGCCGCAGTATCCCAGGCAGGGCGGTTCGAGACCGCCCTGAAGGTGGAAGAGTACGAAGCGTTTTACCGCAGGCTCATCGACGAGGCCCGCGAGCGCGAGGTTCAATAGCGCTTGGTCATACGGTTAGCAGCCCGTCGGACTTGATTCCCGTCATTGCGATCCCGACTTGTCGGGAGAAGCAATCCATGCGCAAGTACCATGAAGATGGATTGCCACATCGCTTCGCTCTTCGCAATGACAGAATCCGAAAAGGATTGGTAACTCCTCTCAGTAGCGCTTGGTCGAGATCAGCACCGAGCGGTAATTCTCCAGATCTTCGAGCACAGCGCCGGTGCCGCGCGCCACGGCGGTCAGCGGGTCTTCGCTGATGTGCACCATCAGCTTGGTCTCCTCGTTGATCTTTTTGTCCAGCCCCTTGATCAAAGCGCCGCCGCCAGCGAGGAAAAGGCCGCGGTCGAGGATGTCCGCCGAAAGCTCCGGCTTGGTGACTTCGAGGCTTTTCTTGACCGAGGTGATGATCTGGCTGATCGGCGTAGCGATCGCCTCGCGGATGGTGGCGGAGTTGATTTCGCGCTCCTCCGGCAGGGCGGTGACGAGGTTGCGGCCACGGACGTTCATGGTCAGCTCCTTGTCGAGCTTGTAGGCCGAGGCGATTCTGATTTTCACCTCCTCGGCGGTGCGCTCGCCGATGGCGAGGTTGTAGGCCTTGCGGAAGTGGCGGATGATGGCGTTGGTGATGTCGGTGCCCGCCACGCGAAGCGATTCGCCCGATGCGATGCCACCGAGCGAGATGACCGCGATTTCGGTGGTGCCGCCGCCGATGTCAACGATCATGTTGCCCATCGGCTCCTTGACGTCGATGCCGATGCCGATCGCCGCAGCCATCGGTTCGGCCACGAGGTAGACCTCCTTGGCGCCGACGTGCTCCGCCGAGTCGCGTACGGCCCGTTTTTCAACTTCCGTGATGCCCGACGGAATGCCGATTACCATGCGGCGGATGCCGAGCGAGAACTGTTTTTTCGTTCTGTTGATGAGGCCGCGGATCAGCTCCTCGGTCGCTTCGTAGTCGGCGATGACGCCGTTTGCCAGCGGTTTGATGGTGACGATGCCAGGGTGCGTTTTTTCGTGCATCAGGAGCGCGTCCTGACCGATGGCGACGACTTTGCCTGTATTGCGGTCGCGGGCGACGATGGATGGCTCGTTGAGCACGACGCCCTTGTTGCGGATGAAAATGAGAGTGTTGGCTGTTCCGAGATCGATGGCGATATCTCTGAACAGGTTACCGAAAAAGCTCATGATGCGTAAGGATCTTGGTATGATGCATAGTGGCTTGGAAGTAGCAGAATCAGCCCGGATTCCAAGGTTTTGAATGAAGCCTAAAAGTACTTAATGGAACCTTTATTTCAAATGAAATCGTAGGCCGTGAAAGCCCAATTTTGAGCCGTCCGGCAGGCCCTCTTCCACCCGGCGGAGTTTCGTTTCAGTGCGCTAATGATTACATTACGCAACGAAACCCAGCGCCCCGCTCGCCGGAGCCATCATCATCCAAAATCCAGAAGCGCCGTGTTAACGATCTACCAATTTCCGCAGGACGAAGCAGCCCTCAGAGAACAGCTCAACCGGACGGTGTCGTTCGATCCGGACGCCCAGAAGACGGTCGATGAAATCCTGCATCGCGTCAGAACCGAGGGGGACGCCGCCGTGCTCGACTACACGGAGCGCTTTCAGGGCGTCCGGCTCGGCGACATGCGGGTGCCGGAGGCGGAGATCGAGGCGGCGTACGCCGAGGCCGATCCGGAGTTCATCGCCATTCTCGAAGAGGCGTTTGCCAACATCACCGCCTTCCATCGCCACGAGGCGGAGAAGAGCTTTTTCTACGAACAGAAGGGGGGCGTGATTCTCGGCCAGCGCGTCACGCCGATGGAGCGGGCGCTGCTCTACGTGCCCGGCGGCAAGGCGGCCTATCCCTCCTCCGTCCTGATGAACGCAGCGCCCGCGAAGGTGGCTGGCGTGGATGAAATCTGCATGACCACGCCGTGCGACGCCGAGGGCAAGGTCAATCCGCACATTCTCGCGGCGGCGAAGGTCGCGGGCGTGACGCAGGTCTACCGACTCGGCGGCGCGCAGGCTGTGGCGGCGTTTGCTTTCGGCACGGAAAGCATCCCGAAGGTGGACATCGTCACAGGCCCCGGTAATAAATATGTCGCGCTGGCCAAGAAGCAGGTGTTCGGCCACGTCGCCATCGACAGCATCGCCGGGCCGTCCGAGGTGGTGGTGATCGCCGACGCGGGCGCGGAGCCGGAGTTCATCGTCATGGACATGTTCGCGCAGGCCGAGCACGATCCCGACGCCTCGGCGGTGCTCATCACCCCATCCGCCGAACTGGCCGCCGCCGTGCAGGAGGCCGCCGCCCGGCTCGCGGGCACGATGCTCCGCGGCGAGGTGATCACCCGCGCGCTCACCGACAACGGCGCGATTGTCGTGACCAGCTCGATGCAGGAGGCGTGCCAGGTGTCGGACATGATCGCCCCCGAGCACCTGGAACTGCACGTGGACAATCCGTGGGAGATTCTGCCCGACCTGCGCCAAGCAGGGGCGATCTTCATGGGGCCGTGGTCGTGCGAGACCGTCGGCGACTACTTCGCCGGGCCGAACCACACGCTGCCGACCAATGGCACGGCGCGATTCTTCTCGCCGCTCTCGGTGCGCGACTTCGTCAAGCACACTTCGATCATCGCCTGGTCGAAAGGCGAGCTGGCCCGCGCCGGGGAGAAGATCGCCCGCTTCGCCGATCACGAAGGGCTTCAGGCTCACGCCGAGGCGGTTCGCGTCAGACTGAAGCACCTGTAAAGATGAAGGTCAACGATTTCGATTACACACTACCCGATGAGCGCATCGCAGCTTACCCGCCCGAAGAGCGCGGCTCGACGCGGCTGATAGTGCTCGACCGGGCGGCGCAGTCGATCACCCATTCCGCCTACGCCTCGCTGCACGAATGGCTCCGGCCTGGCGATCTGCTCGTGCTCAACAACAGCAAGGTGATCCGGGCGCGGCTCGTCGCCCGCAAACCGACCGGCGCTCGCATCGAGCTGATGCTGCTCGAAAAGCACGAGGGCGAGCAGAATCTCGCGCTCTATCGCGGACGACTCCGCGTGGGCGACCTGCTGCTGGCGCATGGCGCGGAGCTGACGGTCGAAGCGCTCCCCAGCGACGGCGTCGCCCGCCTCTCCTGCGCTACGGCGCGGCTCACCGACCTCTTCGAAGCGCACGGCTCCGTGCCAATTCCGCCCTACCTCAAGCGCGACGCCGAGGAGCTCGACCGCGAGCGCTACCAGACGGTCTTCGCCGAATTGCCCGGTTCGGTAGCCGCGCCGACCGCCTCGCTCAACCTCACGGACGAGCTGCTCGGCAAGGTTCGCGCCAAAGGCGTCGAAATCGCCCACGTTACGCTGCATGTCGGTCTCGGCACCTTCCTGCCGATCCGCGCCGAGAGCTTCGAGGAGCACGTCATGCACCGAGAGTTCTACACCATTCCGGAAGCGAGCGCCCGCAAGATCGGTGCAACCAGAGCGGCGGGCGGGCGAGTCGTTGCTGTCGGCACTACCGTCACGCGGGCGCTCGAACACGCCGCGCCGAAGCTCTTTGACGGCGGCTTCTCGCAGGAAGTGAGCGGCGAGGCGGATATATTTATATATCCTGGATATACATTCCGGATCATCGACGCCCTGCTCACCAACTTCCACGCGCCGCGTTCCACCGTGCTGATGCTCACCGCCGCCTTCGCCGGAACGGAGCTGCTCCAGCGCGCCTACCAGCAAGCCCTCGACAACGGTTACCGCTTCCTTAGTTACGGCGACAGCATGCTGGTTGAATGATGGGTTATGAATTGTGAAAGATGAATCGGGGAGAATGTTCAGCCAAATCCTCGCCTTATCCATCCAGCTCGTCTATCCCGTCCACTTCGTCCACAACTATTTTCTCCCGTTTGTTCGCTAACCCGGTTTATTTCTCAAATTCTTAGCTCTTGCTGTAACAATGCCTGAAAAAGTACGGCGATAGCGTGTGGCGTGGGAGAGGAGATTTTGCATTTCATTTATGACCGACTTATTTTAATGCTTTGCCTTTTTCGAGGCAAAAACCATTCCGGTTGTTACCGTTCGCTGTAATCACCATCGCATCATCACTCATAATCATTACCCTGGAGATCATTATATGAGTCTCATCAGCCAGTATCGCGCCCATACTGAGGAGCGCGCTCAACTCGGTATTCCGCCGCTTCCGCTGACCGCCGCCCAGGCTGTCGAGCTGATCGCGCTGCTCAAAGAGAACCCGGTACAGGAGCAGGAGTATCTCCTCGATCTGTTCGTGAATCACATCAGCCCCGGTGTCGATGATGCCGCGCTTGAAAAAGCCGCTTTTCTCGACGCCATCATTCGCGGCGAAGCATCCTGCGCGGTGATCACTCCGGTCGAGGCGGTCGGGATTCTCGGCACGATGCTTGGCGGCTACAACGTCAAGCCACTGGTCGATGCGCTCTCGAGCGCCGACAGCGCGATCGCCGAAGCCGCGGTGCTGGCCCTTAAAAAGACCCTGCTCGTCTACGATTCATTCGACGCGGTGGTCGAGCTGGCAAAAACCAACGCCTACGCCAAAGAGGTGCTCGAATCGTGGGCGAACGCCGAGTGGTTCACCTCGCTGCCGACCCTGCCCGAAAAGATGACCCTCACGGTCTTCAAGGTTCCCGGCGAAACCAACACCGACGACCTTTCTCCCGCCAGCGAAGCCTTCACCCGCAGCGACATTCCGATGCACGCGCTGAGCATGCTCCGCTCGAAGATGGACAATCCCATCGAGACCATCGCCAGTCTGAAAGAGAAGGGCCATCCGTTGGCCTACGTTGGCGACGTGGTCGGTACCGGATCGAGCCGCAAGTCGGGCATCAACTCCGTGCAGTGGCATCTCGGCGCGGACATTCCCGCCGTGCCGAACAAGCGCACCGCAGGCGTGGTGATCGGCGGCATCGTGGCTCCGATCTTTTTCAACACAGCCGAAGACTCCGGCGCATTGCCGATCCAGGCTGACGTGAACTCGATGGATATGGGTGACGTGATCGAGGTTTATCCCTTCCGTGGCGTGATCGAGAAGAACGGCGAAGTGATCTCCACCTTCACGCTCGAACCGAATACGCTGGCTGACGAAGTTCGCGCCGGCGGACGCATCACGCTCATCATCGGTCGCAACCTCACCCGCAAGGCCCGCAAGGTGCTCGGCCTCGGCGAAGAGACGATCTTCAGCCGCCCCGAGCAGCCCGCCGACACCGGTAAAGGGTATACCCTCGCGCAGAAGATGGTCGGCAAGGCGTGCGGCCTCGCTGGCGTGCGCCCCGGCATGTACGTCGAAGCCGAGACCCTCACGGTCGGCTCGCAGGATACCACTGGCCCGATGACGCGCGACGAAATCAAGGAGCTTGCCGCCCTCAGCTTCAGCGCCGACCTTTTCATGCAGAGCTTCTGCCACACGGCGGCCTACCCGAAACCGACCGACGTCAAGATGCATCGCAGCCTGCCTTACTTCATCATGAGCCGTGGCGGCGTGGCGCTCAAGCCGGGCGACGGCGTTATCCACACCTGGCTGAACCGCATGGTGCTGCCCGACACGCTCGGCACCGGCGGAGACTCGCACACCCGCTTCCCGATCGGCTGCTCCTTCCCGGCCGGTTCCGGCCTCGTAGCTTTCGCGGGCGTGACCGGCACCATGCCGCTCAACATGCCTGAATCGATTCTCGTGCGCTTCACGGGCGAACTCCAGCCAGGCATTACCCTCCGTGACCTGGTCAATGCCATTCCGTATGTTGCGATCAAGAAAGGATTGCTGACCGTCGAGAAGAAGGGCAAGAAGAATATCTTCGCCGGTAAGGTATTGGAAATCGAAGGCTTGCCCCAGCTCAAGGTCGAGCAGGCGTTCGAGCTTTCCGATGCCTCCGCCGAGCGCAGCGCTGCTGCCTGCACCGTGCGTCTCGACAAGGAACCGGTGATCGAATACCTCCAGTCCAACGTCAAGCTGCTTGGTCAGATGATCGAAGAGGGCTACGGTGATGCAGAAACCCTGCGCCGCCGTATCGGTAAAATGGAGGAGTGGCTCGCCAAACCGGAGCTCCTCGAACCGGATGCTGACGCCGAGTACGCGGCGGTGATAGAGATCGACATGAACGAAATCACCGAGCCGATCCTCGCCTGCCCGAACGATCCGGACGACGTGGCCACGCTCAGCGAGATTCTCGCCGACGAGAAGCGCCCGAAAAACATCGATGAGGTGTTCGTGGGAAGCTGCATGACCAACATCGGCCACTTCCGTGCGCTTGGCGAAGTGCTGCGCGGCAAGGGTCAGGCCAAAGCGAAACTCTGGGTCGTGCCACCGACCAAAATGGACATGAAAAAGCTTGTCGAAGAAGGTTACTACGCAGTCTATGGTACCGCCGGTGCTCGTGCCGAGGTTCCGGGTTGCTCGCTCTGCATGGGCAACCAGGCTCGCGTGGCCGATAACGCCGTGGTCTTTTCGACCAGCACGCGCAACTTCGATGACCGCATGGGCAAAGGCGCGAAGGTCTATCTTGGCTCCGCCGAGCTTGCCGCTGTGTGCGCGCTGCTCGGTCACCTGCCGGGCAGAGAAGAGTATATGGAGATTGCCGGTTCGCTCTCGAAGAATGGCGACAAGGTCTATCGGTACCTCAACTTCCACGAGGTGACCGCTCAAGAGCTGCAAATGCTTGTCGATTAATTGATTAGGGGTGTCTTTCACATCACCGCGTTTGTGCGGAAGACGAAGTGATGACGCCCCTGTCTTTTGACTTTTGTGGCTGATTTGTCCGTTAAAGTCTTGATTTGGCGAAATCGCACAGTATAATGGTTGCGAAAATCTGTTATTAAAAAGTACCTGTGTGTCGAGTGTGTTTTTTTGAAAAATCGGCGATTTTGCTTATAATTCGTGAGCTGAACAAGCTGTAACATTTTTTTATTTGAACCAAAACTGCATTCGAATCATGAAAAAACTTTTCGTGTTCATGTTCCTCCTGAGCTCGGTCTCTTTCGTTGGTTGCGCTCAGAAAGCTGAACAGCCGGCTGAAGCTCCTGCCGAAGCTCCTGCCGAAGCTCCTGCCGAGGCTCCTGCCGCTGCTCCTGCTGAGGCTCCTGCCGCTGCTCCTGCTGAAGCTCCTGCAGAGCAGGCTGCTCCTGCCGCTGCACCTGCTGGCGAGGCAAAATAAGTTCCTGAACAAGGACTTAAGCAAAAAAGAGACAGAGGCAACTCTGTCTCTTTTTTTTATGCCTGCCGTAAGTGATAGCTGAGTCGGTATTTGTCTGGAATTGAAGTATCTGATGCTATCGCGCACTCCCCTGTGCGCCAACATTTCCCGCCTATCCGGTTGATCATCAGGTTTCTGTGCTTTGCGTACTGATCTGTAGAAGTTAAATAATACTCCGATCTTTCTGCTTTCTCTTGGGTGTCCGTTGATGATTCTGATAAGAATAAATTATCCGTATCAGACAGAGGCGAGTGTCTTGACTGAAATCAGAGACAGTCGAAGACGATTTCACGGGGATACTCAGGTGTGATTGATCCAGGCGCACTGTTTGTTGGCTCGACAATAATAGTCCGGAACTGAAAAGTATCGTGATATAGCCTTGAAAACCGGCTCGATCTGGTACTTTTTGCATTCAATTCACGGTGATTGGGTTGATGGGTTCTTTGCGGCTGAAGCAATATTGTGAATTGATAAATTTGGTTCTTCGTAAGATTTAATGGTAACGCTCGTCAGCAATTACGTCAACCGGTAATAGCCATGTTGAGCTTTCCACAGTAAAACAAAATCCTTATGCGGTAGCTGTGAAAGCTGTGGAACCCACGGGCCGATGCTTTGTACAACTGGATCTTGCTGTTCAGACCTTCGGAAACTGCGTTGGTCATTTCGTGCTCGAAATAGTTCAGGATGTTGTCGAGATGCCGCTTCAGCAGCTCTTTGACCTTGATCATGGGTTTCAACGCTAACTGGTCAACGCGTTCAGACCAGTAATCGAAAAAGAAGCTTGCACTCTCTCGACAACCCAGCCGCCAGAACTCCCGAAACATGTTCTTCATCGACCAGGCTTTTCCGGTTTTCAGCTCACAGGCCATCAATTGATCAAAGCTTGTCCGCTGGCTTTCCGTCATGTTCTCCGGATTGCGCAGCCAGGTGAATTTCGAGCCAATCAGAGTCCTGTCCCCTGCATGATGAAGTTGACGGGACTCTTGGCGACGAACCGTGTCGACCGCCTCGTTCAGATATTTGCTGATATGGAAACGGTCATGCACAATATCGGCCTGCGGCAGATGCTTTTTGGCAGCAATCGCGAAGGGTTTCCACATATCCATCGAGATCGATTTCACACCCTGGCGTTGCGATGCTTCAAAGCTGAGGAGTAGCGCTTCTGCTCCATCGGTCGTTCGGCTCTGGACCACCTCAAGTACCCGGCCACCTTTCAGGTCGTTCAGGATCGTCACATACTGATGGCCTGCCCGGAAGCTCTTTTCATCAAGACCAAGATGAGCAATCGCCTCCTTATTCCGGCGGCTCAGGCCTCGCTTAACTGCACGGTTCATGATCTCGTTGGTTGCATGCCAGTTCAATCGCAAGAGCCTCGATGCCGACTGAATGCTTGAACACTCCTGAAGCAACTCGACAGCAAGCGCTTCAAACTTCAGGGTGTAGCGCGAATAGCGCGTTGCCCACGGAACTTGAATTGTCTTGATCCTGTGCTCTTTGCACTCACACCGAGGCACCCTGGCTATCAGATGCGTCTCGTACTCCATGGTATCCAGATGCCGCCACCGTTGTTCTGGCGCCAGGTCATAAATTCGTCCGGCCTTGCCGCATTCAGGGCATTCGACTTTGGGTCCGATATACTCCAGATGGATTTCTATCCGGGGGCCGGACGTCGACAGCCGGACATCAGACACCTTCCATGTTTCTGGTAATCCTAATAACTGCTGGTAATGGGTAATGAGGCTCGGCATACGTTGGGGTTAGTGTTTTGGCGTTCTTGGATAAATTACACCAAGCCACTCATTTTTACTACCAGCCCATTAAATTCTGCGAAGAGCCTTTTATATTAATTGTTAATATCAAGCTTCCGATATACAGGCAATGTTGTATGCCATATCGGAACATGAATACAGGAAACCGGAACAGGGAGACGGGGCGCTCCACCCGGCGAGTCAGAATTCAATGAGCCTCGAATTTAGCCGGGTTTTCCGTTCATACGTCACTTCCGGTTTTCAAGCAGATGTGTTTGAAGGTAGCGAAGCTTTATGATTCCGCCCGGAATCCCGCGTTCCTTCGTCCCGACGGAATACACTCCGGTTTTCACCCCGGCCGCTTCGTCAAAAGCCGATGGCCTCGATCTGCTGCGCCTCAACCAGATTATTTCAATCAGATGAGCTTTCCGTACAAAGCATCCGTCAGCATCCCGATGAGGACGTTCAGAGTTCGATCGGCAAGATCGCCAAACAGATAAACCGGGCGAATGGTCATGAATGCCCTCCAGGACAGCGCAGGAACCATACCGTACGCTCCCGACAAGTACACGACGGTACTGATTGTCGATGCCGATCCCGACTCCCGAAGCCATACTGCCGCCAGCGTAGAACAACTCGGCTATACGGCACTGACGGCCGATAGCGACGAGGCGTGCATCGAACTGTTCGGCACCTGCATGATCGAGCTGCTGCTGCTCGACATCAACGAACCAAAGAAGACCGGCCTCAAGGTGCTCTCCTGGCTTCGCGAGCACGGCATATCGGTTCCGGTCATTATCATAACCAGTTCGAGCGACATCGAGCAGGCCATTTTCTCGATGAACCTGGGTGCTTACGCATACCTGCTCAGACCGGTCAGCATCAACCGGCTCGGTGTTATTAATCCAGCCAATAAAACTCGCAAATATATTATATTGCGGGTATGGAAAAAATCGATATTAGAAAAGTCTCTGACCGGGAGCGCGCTTTATTGCGCAACCAGGTGATTCGCTTGCGAAAGCAAGGCAAAGGCAACAATGAAGTTGCCGAACTCTTGGGGTTGTCCCCTGAAACAACGAGTCGTTGGTGGCAACGATACCAGCGAGAAGGCCAGTCCATGCTTGCGGAGCCAAAACGGGGTCGAAAACATGGAGAACAAAGGAGTCTGAATCCTGAACAGGAAAAGAAGATTCAGAAAATGATTGTCGATCATTACCCTGAACAACTGAAACTGCCATTCGCGCTTTGGGATCGTCAGGCAATCCAACTCCTGATTCTTCAGCAGTTTGGCATCAACATGCCGATTCGCACGGTTGGCCACTACCTGTCACGCTGGGGCTATACACCGCAACGTCCGATCAGGAAAGCCTATGAACAGCGTCCAGCCGAAGTCGAGCGCTGGATGCAGGAGTCCTATCCAGCCATCAAAGCGAAGGCAAAGACTGAAAATGCCGAGATTTACTGGGCTGACGAGACCGGCATCGCAACCAATGGCAACCTGGTCAGAGGCTATGCTCCTGCCGGAAAAACGCCTGAGTTACGACTGAATGCGCGCAAGGAGCACATCAGCATGATTTCAGCGATCAACAACCAGGGCAAGCTTCGTTTCATGCTCTATGAAGATGCCATGAACAGCAAACGACTCATCGAGTTCATGAAGCGTCTGGTCAAGGATGCAGGCCGAAAAGTGATCCTCATTCTGGACAATCTGAAAGTGCATCACAGCAAACCGGTCAAAGAGTGGCTGGGAAAGCATACGGAAAAGATCGAGGTGTTTTATTTACCGTCCTACTCACCGGAATTGAATCCAGACGAATATCTGAACAACGATTTGAAACACGCCGTGCATGGCAATTATGGTGGAGTAGCCCGATCAAAAGCGGCAATTCACGACAAGACGATTTCGCATATGAGACATCTTCAGAAAAGTCCTTGCAAAGTCGAAAAACTGTTTGATCATCCCAATGTTCGCTATGCCAAAAATTGATACCTTTATTGGCCGGAGTAATACCATCCGGAACGCCCTGACCGAGTTCGAGCTTCGCAACAAGCTGATGCTCTTCTCGGCGGCCATCACGCAGCTTCCGATGGCGGTGGTCATCACCAGCGACCAGGGCATTATCGAATACAGCAATCCAGGCTTTACCGCGCTGTCGGGCTACACGGAGGCGGAGGCAAAAGGGCAGCCGATGAGCATTCTGAACTCCGGCGTGCAGTCGAAGGTCTTTTACCGGAATTTCTGGGAGACCATCAACGCCGGAAAAATCTGGCAGGGCGAGATCGTCAACCGGAAGAAAAGCGGCGAACACTATACCGAATACTGCATCGTCTGCCCGATCACCGGCCCGGACGCGGAGATCGTCCATTTCATCAGTATCAAACAGGATATTACCCAGCGCAAAAAGGAGCAGGAGGCGCTGGCCGAAAGCGAGCAGAGCTTTCAGGAGCTGGCCAACCTGCTGTTGCAGCCGGTTTTCGAGGTCGATCTCAAAGGCAACATCGTCTTTTCAAACAAGGCCGGACTCGACCTTTTCGGCTATACCAGATACGATATAGAGGAACAGGAGTTCGAGGCGATCAGGCTCTTCGCTCCTGAAGAGCGCCCGCGGGTGTTGCAGAACATGGCGGCGAGAATCCAGGGGATAACCTTCGAAAATCACGAGTACACCGCGCTGAAAAAAGATGGCACGCCCTTTCCCATTCTCATTTACAGCGAACCGATCATCCGGCGGGGCATTCCTGTTGGCGTTCGCGGCCTCTGCCTCGACATTTCCGAGCGGAAACGCAACGAGGAGAAGCTGCTGGAGCTCAACCAGACGCTCGAAGAGCGGGTGGAGGAGCGCACGAGGGAGCTCGAAGTGACGCACCAGCAGATGATTCTCCAGGAAAAGCTCGCCTCGATCGGCCAGCTTGCCGCCGGTCTGGCGCACGAAATCAATAATCCGGTCAACTTCGTCCGGATCAATTTCGCTACGCTCCGGGAAGATGTCAGCGATCTGGGCCAGCTCATCAGGGAGTACCGGGCCGTTTTTCAGGAGATCGAACACTCCGGCCTGGCCCCCGAAGCGATGGAACGACTCAAGGCTCTGGAGAAAAAACTGAAGGTGGATGAAGTGCTCGACGAGCTGCCGGAGCTGTTCGACGAATCGCGGCGGGGCTTCGAGCGGATCGGCACCATTCTGAGCAGCATGCGCAACTTCTCGTTCCGCCACGCGCTCAACCAGCGCGTGCCGTTCGACCTCAACCAGGGCATCCGCGATACGCTCATCATCGCGCAGAACGAGTACCGCTACTATGCTGAAGTGGAGACCCGCCTCGGCGAGTTGCCGGCAGCACCCTGCAACCCGGAGCAGATCAACCAGGTCTTCCTGAACATCGTCGTCAACTGCGCCCACGCCATCGCCTCGCAAAAGCGGCACGAAAAAGGACGGATCGTCATCGAGACCGGAAACGGAGATGACAATGTTTGGTGCACCATCACCGATGACGGGCCGGGCATCCCGGAACAGATCAGGAACAGAATCTTCGAGCCTTTCTTCACCACCAAGGATCCCGGCAAAGGCACCGGCCTCGGTCTGAGCATCTCATACGACATCATCGCCAACAAGCATGGCGGCAGCCTCACCGTCTCCTGCCCACCGGAAGGAGGATCGGTCTTCACCATCCGGCTGCCGCTGAAAGCCGCCGAAGCATCGACATCATCATGAAACAACGTGACGAACTCGCCATCCTTTTCGTCGATGACGAGTCTGACATTCTCCACTCGCTCAACCGCTTCCTGAGAAGGGAGGAGTACCGGAAATTCTTCGTGGACAATGCCGCTGAGGCGCTCGACCTGCTCGCCGGAACCCCGGTCGATCTGGTCGTTTCCGACCTTCGGATGCCGGGCATGAACGGCCTCGATCTGATCAAAGAGGTCAAACGGCTCTACCCCGGCACGCTGCGGATGATCGTCAGCGGCTCCCAGGACATCGAACAGATCATCGAATCGGTCAACAAGGGCGAGATTTTCCGCTTCATTCCCAAGCCTGTCGAACCCGAGTCGTTCAAAAGCATCCTGAACGACGCCCTCGACTACTACTGCATGAAGCTGGAACACGAAGAGCTGTTCGACGAGATTTCTCTCAAAAACGGGCAACTGACCGAGGCCAATACCACTCTCGAAAAGCTTGCCAGCGACCTGAAAAGAAGCGAGGCTCAGTTCCGTTCTATGAACGACGCGGCGCAGGACGCTGTCTTCATGCTCGACGAGAACGGCCTGATCCGCTACCGGAACACCGCGGCGGAGGTGATGTTCGGCTACCGGAGAAGCGAACATCCGGCGCAGCCGGTCTCCGAAATCTTTCCGGAACCGTCAACGGCGCTGGAGCTGAACGATCTGGTCTCCTGCGACTCCGTCCTTCTGGCCAGGAGCTGCGCAAGCCTGGTCATCCAGATCGAGGGCATCAGGATGGATGGCTCCCGCCTGCCTCTCGAAATTTCGAGAGGGTGCGTGCACCTCGAAAACGGCCCGCACAGCGTGCTCATCGCGCGGGACATCACCACGAGAATCGAGGAGGAGAAGAGTCGCAAGCACTACGAAACCATGCAGAAAGAGCTGGAGTCGCAGATTGAGAAAAAACTCTTGCAGAGCCAGGCCCCCATTACGCTCCGGCACATCGAAATCAGCTACCTGATGCACTCCTCCGGCCATCTCGACGGGGACTTCACCGAACTGATCGAGTACAATCCCTTGCAGGCCGACCTGCTCATCGGCGACGTGATGGGCCACGGCATCCAGTCGGCTCTCGTGAGCGCGGGAATGAAGTCGCTCTTCCTGAAGAGCATCGCCGAAGAACGCAACAGCCCGGAAGCGCTCCCGCCGCTGGAGCGAATCGTTGGACGCATTCACGAGCGGTGCATTCACGAGCTGATCGATCTCGGCATGTTCGCGACCCTTCTTTTTCTGCGACTCGACCTGAAATACCGGCAAGCCGTCTTTGTTGATTGCGGCCACAACCCGCTCATCCACCTGCCGTCGAAAACGGGGCGCTGCCGTCTGGTCAAGGGCGACAATCTGCCGATGGGAATGATCGAAGAGGAGGAGTACCGGCAATCGGAGTTCCCGATCGATGAGAACGACCTGCTCGTGCTCTACTCCGACGGGATCACCGAAAACCGTTCGCCCGGTGGCGAGCTTTTCGGCATCGAACGCTTCACCGCGCTTCTCGAAGAGCACGCCGCGCTGCCGACCGAAGCGATTGTCGAAAAAATCGAGGCGGCGCTCATGTGTTTCTGCGGCTGCACCAATTTTGCGGATGACGTCACCTGCATCGTGATCCGGATCAGCGGAAGCACGGAAATACCGGATAACGGCTGAAGTCCGAAGCCAAAGAGAACCTGCGCATCGAACCCTTGCCGATGCAGCGATGACAACCCGATCGACAAACCCCGAAAAGCGCACCCCGTCAATGACCGACAACAGATCGGCGCAAGAGGCCAGAGCGCTGGAAAAGCGGCTTAGCGGACGCTCAAAAGGGCGGCGCGGCTGGCGGCGACACGCGGCGTTCGCCGTGAGCACGGCGCTCTCTGAGCTGATCGTGCGGCTGATCGAGATTGGCGTGGCGCTCTCGGTGACACTCTTCGCCTTCGTTCCGGTGCTGCTCGCGCGGCTCGCGCACCGGCTGCCCGCCGGAAAGCCGGTGTTCTCGAAGCGCGCCGTGTTTGGCCGTTCGGGCAAACCGCTGACGCTTCTGAGCTTCGACGGCCTTTCGGGCGGCATGGCCACGCTGCCGTGGTTCCTGGAGCTGTTCACCGGACGGATCGCCCTTGCGGGCACGGCGATCCGTGACTGGCATCCCGCCGCCGCGCCGGAGCAGGGGTACATCAGCATGGTGAAACCGGGCATCGTTTCGCTCTGGAATGTCCGCCAAAGCAGCCGGATCGCCCACGAGGGACGCGAAGCCACCGAGTGGGAGTACATCTTCAGCAAGCGTCCGGCGTACGACTTCCTGCTGATCCTGCGCGCGCTTCCGGCCCTGCTCTTTTCCGAAAAGGAGGCCTCGCCGTCACCGCTCTTCAATCTGCTCGACCTGAAGATCGACAACATCTCGATGCGCGAGGCGATCTCGATGATCCGGCAGTCGATCGAAGAGCAGCGGCAGTCGGCCATCTTTTTCGTCAATCCGGACTGCATGAACAAGAGCGTCACCGACCGAGGCTACCGCAAGGCGCTCGCCTCGGCGGATCACATCCTGCCGGACGGCATCGGCCTGGTCATCGCGGGCAAGATGCTCGGCACTCCGCTCTGCGAAAACATCAACGGCACCGACATGCTGCCGTTTCTGTGCGAAATGGCGGCAAGCCAGAAGCGCTCGATTTACCTGCTCGGCGGCAAGCCCGGCGTGGCCGAAAAGGCGGGCGACGCCATCGCGCAAAACCACGGCGTCACCATCGCGGGCGCAATGCACGGCTACTTCGACCATGAAACGGAGAGCGCCGGAGTGATCGAAGCCATCAACCGCTCGAACGCCTCGATTCTGCTCGTGGCCTTCGGCGCGCCGCTCCAGGAGCAGTGGATTGTCCGTCACCGCGCGGCACTCCGCCCGGCGATCCTCATGGGCGTGGGCGGCCTGTTCGATTTCTTTTCGGGAAACATCCAGCGAGCGCCGCGCTGGATGCGGGAAATCGGGCTGGAGTGGGTCTACAGAATTTTGCAGGAGCCCGGAAGAATGTGGAAACGCTATGTCGTAGGCAATCCGCTGTTTCTATACCGGGTCATGAAATGGAAAGTGCTTGGCCAAAGCTCGAACCCAGAAAATCAATGGAACTCGATCCAACCGTCCGGCGGGAACTGATCCGGAAAATCGGCGGCAACATCCGGCCATCGCTCCGGCTCCGGGGCAAAATGAAGGTTGCCGCCTGGGAGAACACCATCCGCCTCTCCTACCTTGCCAAGCGCCTGCTCGACATCGTGGTTTCGACGCTCGCGCTCGTCGCGCTGCTGCCGGTTTTCATCGTCACGGCGCTCTCGATCGTGGTGGAAAATCCGGGGCCGGTCTTTTTTGTCCAGATACGAGTCGGCAGGAACGGGCGGCACTTCCGGTTCTACAAGTTCCGCTCGATGGTGGTCAACGCCGAAAAGCTCAAGACCGAACTCGCCGCGCATAACGAGTCGAAGGACGGCGTGATCTTCAAGATGAAAAAAGACCCGCGCATCACCCGCACGGGGCGCATCATCCGCAAATTCAGCATCGACGAGCTGCCGCAGCTCATCAACGTGCTCAAGGGAGACATGAGCCTGGTGGGGCCGCGCCCGCCGGTGCCGAAGGAGGTGGAACAATACACCCTCGAACAGCGCAAACGGCTGCACGCCATTCCGGGCATCACGGGGCTGTGGCAGGTCAGCGGCAGGAGCGACATTCCGTTCACCGATCAGGTGCGGCTCGATTTGCAGTACATCCAGAGCGCCGGCGTCATCAACGACCTGCGCCTTCTCCTGAGAACCATCCCTGCCGTGCTCAGCGGCAAGGGCGCATACTGAAGGAAACCGACATGAAATTCACGCTCGACAACATCGACGGCCAGCTTGTGGGCATCGCGGAGCTGGAGGGACGACTCGACGCCCGCAACAGCAAGCCGCTGCAGAAAACCTTCCTCGAATGGCTGGAAAAAACGCCGTTCCTCGTGTTCGATTGCAGTCTGCTCGATTTCATCGACAGCAGCGGGCTGGGAGCCATCGTGGGCTGCCTGCGCAAGGCGCTCGAAAAGGAGGGCGATCTGAGGCTTGCCGGAATGAACGAAAAGGTGGGCATGGTCTTCGAACTGACGCAGGCGAAGCGGCTCTTTTCGATCTTTTCCAACGGGAACGAGGCAGCTTTATCGTTCGCAGCGAAACCCGATTCAGGAACCGGGAGATGAAAACCATCCTCGCTTTCAGGGAAGAGGCGTTTGCATGGAGTCACGAGGTTTTTCCCTGCGTGCACCCGCTGCTTTTGCCGCTGTGCAACAAGCCCTTCATCGAATACCTGATCGATCTGGCAATCCTGACCGGCAGCACGGCCGTTCGCATCCTTTGCGACGGCGGGCTTGGCCCGGTGGAGCGCTATTGCGAGGATGGCAGCCGCTGGGGCATCGCGCTCTCCTACGAAAGCCTTCATGCCGATGATACCGTACCGATCCTGCTCGGCAAGAACCGCAGGTTTTGCGGCAGCGAGCGGATCATGGTCGTCAGCGGCTTCTCGTTCATCCGTTACGACAAGCGGCTCGACTACAAAAGCCTGGCCGGTTCGCGGCCCGAAGGCGAATGGGTCTCGAGCCCCGGCGGCAGCATCACGCTCTCCGGCCCGCCGGAACAGCCGCGGACGGACGGAACAAACCCGCCGTTGTCGCTCATGCCGCTCGACGGCCTGGCGACTTACTACCGCGCGTCGATGGAGGCGCTCGAAACCGGCGCCGACCGCTACGTTCTGCCCGGCTACGGCGGTGAGCCGGGGTGCTCCATCGGCAGGAACGTGGTCATCAGCAAATCGGTGCAGATCCGCAAGCCAGTGAGCATCGGCAACAACGTCCAGCTCCTCGGCGACACGATCATCGGACCCTCGGCCATCATCGGCAGCAACGTCATCATCGACCGGGAAAGCTCGGTGGAATCGAGCATCGTGCTCGACAACACCTACATCGGCGAGCACCTCGAAGTCAACGGGCGCATCGCCTCGGGCAACCGGCTCAACGATCCGGTAAGCGGCGCGTCGATCTCGATGGAAGATCCGCACCTTCTCGGCAGCATCAAAAAGAGCCGGGCCCTGAGCGCCCTTCCGCGCAAAATCGCGCACGCCCTCGCCGCGCTCGTCATGATCGCCGTGCTCTCCATTCCGTTCCTTCTCCTCGCGCCGCTGCTCAGGTTTGGCGGACGGTGGAAATCGGCCCGGATCGAATGCCTTTCCGAAAATCCCGACGACACCATCCCGCTCGGCAAGGTCGAGCTGGATACCGTAAACGCGCCAGGAGCGATAGCCGCCGCTCTTTCGCTGGATCGCTATATCTGGCTTTTCCGGGTGCTCACCGGCCAGCTTGCGCTCATCGGCAGCACGCCGCTTCCGGCTGACGCGAACCAGCCGAACTCTCCGGCAAACGCGCTCGCTTACCGGCCCGGCGTCTTCAGCTACGCCGAAGCCGAGGAGTGGCCCGCGACCGGCGGCGACGCGGCCATCGTCGAGCGCTTCCATCTGACGCACGGAAGCACGCTCGCGGACATCGGTCTCTCCATCAAGGCTTTCATCAACCGCCTTCAGGAAAAAAGCACTGTATGATCATCACCGAAACATCGAATGACGGCATCGCCATCGTCGCCCTCGAAGGCACGCTCGATGCCCTCTCTGCTCCGGAACTCCGGAACATCCGCTCGGTCACCGACCCTGAAAAAACGGTTATCCTCGATCTGGAAAAGGTGGATTTCATCGACAGCAGCGGCCTGGGAGCCATTGTCGGCGCGACGAGGGTGAAACTCGATCCGGCCCGCGGCGTCGTGCTCGCCTGTCTGAACGACCGCGTACGCAAAGTCTTCGAGATCACCAACGCACAAAAGCTCTTCCATATTTTCGACGACACTTCGGCCGCCGTCGATTTCGCGGCAACCCGGTAAAGCACGCGCACATGAGTAAAATCATCACACTGACCCTTCCGGGAGAGCGCGCCTTTGCAAGGATGGCTTCGCAAACCGCCTCGTCGATTGCCGATTTCGTGACCGGCGACGCTCGGCAGGAACCCGCAGGCCGGGAGTTTTCCCATGCCTTCGAACTCGCCGTCAGCGAAGCCTTCACCAATTCTGCGACCCATGACGACGCGTGCGCCAACATGCCGACGGTCACGCTCACCTTCGAGTTCGAAGAGCGGCAGCTCACCGTGAGCGTGCGCGACGCCAACGAACCATTCAGCATCGAAACGCCCGCGCCCGACATCGAGAACTACCCCGAAAACGGCTACGGGCTCTGGATCATCCGCAAGGTGATGGACAGCGTCACCTACCGGCGCGAAGGAAATTCGAACATCATCTCCATGTCTAAAACACTCTAACCGATGGTCACGGTCGTCATCGTCAGCTACAACACGCGGGAGATTCTCTCCAACTGCCTCGACGCGCTCTTCAAGAGCGGCATGGGCAGGGAGATGGAGGTCTTCGTGGTCGATAACGACTCCCGCGACCGGTCGGCGGAGATGGTCGCCGAGCATTTTCCGGAGGCGCGGCTCATCGCCAACAAACAGAATCTCGGCTTCGCGGCAGCGAATAATCAGGCGTTCCGACAAGCCACCGGCGAGTACATCGTGCTGCTCAATCCCGACGCCTACGTCCTTCCGTCGTCGATTCCCAACGCCGTGCGCTTCATGGACGAGCACCCGGAGTGCGGCCTCTGCGGCGGCAAGATCATCTCGCCGGAGGGACGACTGGAGCCGTCGGCGCGCCGCTTTCCCTCGCCGTTGACCAAGCTGCTCACGCTCTCGGGCCTCCGGGCGAAGTTTCCTCAATCGCGCTTGCTGAACTGGCACGAGTTCGGCGACTTCGCCCACGACCGCCCGATGGAGGTGGACTGGGTGCCCGGCACCTTCACCATCGCGCGCAAGGCAATGCTCGACAAGATCGGCCCCTTCGACGAGCGCTTCTTTATTTATTACGAAGAGACCGACCTCTGCCTGCGGGCAAAAAAGGCGGGCTGGAAGGTTTATTTCATCCCGGACGCCGAGGTGATGCACATCGGCGGGGCGAGCAGCAAGACGCGCAAAGACAAGACCTTCGACAGCGCCGCCTCGCAGGTGCTCTCCTTCCGGATGCGCAGCGAGTGGCTCTACTACCGCAAAAACTATGGGCTTGCGACGATGCTCGCTAGCGCAGGCATCGAGCTGCTGTGGTTCTCCATGCGCTACCTGAAAAACCTTCTGATTCCGACTGGTGACGCCGCGCGAAAAAAAGAGATGGCCCGCTCGACCATGAGCCAGATCACTCGCTCGGTCTCCGACACGCAGTTTGGACAGTTTTCGCCGCCAATTCCCTGGTAAGTGCTGATGGCGCTCTTCAGCAACATACGGGCCGACCTGAAAACTTACGGCGGCCAGTGGAGCCAGCAGGGGTTCTGGGTGATGATTGTCTACCGTTACGGGCGGTGGCGTTACGGCATCAAAAACAGCGTGCTGCGCAAGCCCTTTTCGCTGCTCTACCGGTTTTTCTATAAAGTGGTGCAGATTCTCACCGGCATCGAATTGCCGTGCGAAGTGCCGGTGGGCAGGAACTTCCGCATCGACCACTTCGGCGACATCGTCATCAGCGGCTACGCGAGCTTCGGCGACGACTGCATCATCCGCAACGGCGTCACCGTGGGGCTGAAGAACATCGAGGAGAAGGCCGCGCCGAAGATCGGCAACAACGTCAACATCGGCGCGGGCGCCAAGCTGCTCGGCAACATCACCATCGGCGACAACGTGGATGTCGGAGCCAACGCGGTAATCATCTCCTCGGTGCCCGCAAACTCCATCGCCGTAGGCATTCCGGCCAGAATCATCCCGAAAAAGTCCTGACCGACAACTCTGCTTCATGAGACGAACCGAACTGTTTTTCTCTCGCCGCATCCGGCAAACCGGCGCAATTCCCGGCGACTCCCGATTCAGGCGGGCGAGCATGCTGCTCTGCTCGCTGCTCATGCTCATGCTCTCCGCGTGCAACTCCATTTCGCCGAAAGAGACCACCGTCAGCGAGAAAGGCGAGAGCAACTTCAAAACCGAGCTTCCGAAAAAAGTTCAGGAGTTCGCAACGCCCGACCGGCTCAAGGCGCTCGATACTCAGGAGGTTTTCCAGTACCGCCTCGGGCCGGGGGACATGATCAGCATTCAGGTGTGGCGGCGGCCCGAGCTGTCGCAGGAGGGCATTCTGGTTTCACCCGACGGCTTTCTCAGTGTGCCGAGAATCGGCAACGTTCAGGTGCTCGGCATGACCGTCGCCGAGGTGAAAGCGCTGGTCACGTCGAAACTCGAATTCTTTTACATCGAACCCGAAGTGACCATTCGCGTCCAGCAATTCCACAACAACAAGGCCTTTGTGCTCGGCCGGGTGAGCAAACCGGGAGTCGTCAACTTCCCCGGCAAGGGCACGCTGCTCGAAGCTCTCGCGCTGGCGGGCGGCATTCCCGACCAGAACAAGGACACCTCGCTCACCAAGTGCGCCATCATCCGGGGCAACGACATCATCATCTGGATCGACCTCCAGGATCTGCTGCGCAACGGCAACATGGCGCTGAACGCACCGGTCAGGAACAACGACGTGATCTACATTCCGGAATCTTCGGACGAGATGGTCTATGTGCTTGGCGAGGTGCAGACACCGGGCGCGATCCAGATCAGGAGCGGCATGACGGTGCTGAAGGCGGTGATGCTCGCCGGAGGCATCAACAAGAACGCCGATCCCGAAAAGGTGTTCGTCATCCGCCAGCAGACGCTCAAGGGCGACGTCATCAGGGTGAACCTGAAAAGTCTGCTCGAAAAAGGCGATTTCTCGCAGAATTTCAACCTGATGGCAAACGACATCGTTTACGTCAGCCCCGGCGGCATGACCAAACTCAACTATTCCATCGAAAAGATTTTGCCCTCCATGCAGATTCTGAATCTCGGCGTCGGTCAGTCCAGCTTTATTTACGGCACTCCTTAGCAATCAAGACAGCGTAGTTCCCTTGCAGAAACCCTCGTTAACCATCATCCCCTCCGTTCCGGTCTGGAAACAGGGCGAAACGTTGCGGTTCGACCGTAAATTTTACGATGGTCTCCTGCGCTATACCGAACTCTGGCCGGGGCCGATAACCTGCGTGATGGCGCAAAGCAGCTCGCCGCTCCCGGATTTCGGCGTCGTCGAGGCAACGCCCGGCGTGATGCCCTTCACCTGCATCGCGCTGAAGGAGAGCGAAATCGTCGGAAAAGAGCATATCCGGGACGCCACGATCGTGCTCGCTTCGGCGGATGCCCACGACCAGCTCCACCTCGCCGCCCTGTGCCGACAGATGGGGGTAAGATGCGTTTACGTCATCGAGTACATTCCCGAAACCCGCTACCAGATCGCCGCTCTCGACAATCGCAATCCCGCTGCGGCGCTTCGACAGAAACTCTATCTCTGGCTCGGCGAGCGCAAGCGGCGCAAGGCTTTCGAACTGTGCGACGGGCTTCAGTGCAACGGCACGCCAGCTTACCATGAGTACCGGGAGACACCGAACCGGCTGCTCTATTTCGACACGCGGGTCTCGAAAGAGCAGCTCATCGGCGACGCCGAACTCGAAGCGCGCCTTGCCACGCTCAGGGAGAAAAAGCCGCTCCGGCTGGCCTTCTCCGGACGGCTCGTGGCCATGAAGGGGGCGGATCACCTCGTCCGGCTCGCCCTGAAACTCAAAAAACTGAATCTCCCGTTCCACCTCTCCATCTACGGGGCGGGCGAGCTGGAAGCGGAGATGAAGCGCTCTATCGAAAGGAACGAGCTGAACGAGCTGGTAACGATGGAGGGCGCGGTGGACTTCCAACGGCAACTCTTGCCCGACCTGAAGAAGAAGGTCGATCTTTTCGTTGCCCTGCACCGCCAGAGCGACCCGTCGTGCACGTACCTCGAAACCCTCTCCTGCGGTGTGCCGATCGTCGGCTACCGCAACCAGGCTTTTGGAGGGATTCTTGATCTTGCCGAAATCGGCTGGGGCGTCAAGCCCGATGACATCGACGCGGTCTCGTGGATGATTCTCCGGCTCGATCTCGCTCGCGATGAGATTGCCGAAAAGTCCGGAAACGCCGCTGGCTTCGGTCGCCAGCACGATTTCGACACCACCTACAGGAACCGGATCGACCACCTGCTCTCCATAACCAATGGACGGAAACGCTCATGAACGAGAAAGTCAACATCGTCTTCGCTTCCGACAGGAACTACATCCAGCACCTCTCCGTCGCGCTGGTTTCGCTGCTCGTAAACAACCGAGAGCTGGCGTTCACCGTCTATATCATCAGCAGCGGCATGACGGCAAAAGACCGGCGCAACATCGACGGAATCGTAAAAGGATACGACTGCGAGGTGAGGCATCTCACCGTTTCGGACGACCTCTTCGTCACGCTGGCCACCGAACACCCGATGTATCCGAAAGGCATCTACTACCGCCTGCTCATTCCCTCGCTCATCGACGAAGAGAAGGTGCTCTACCTCGATTCGGACATCGTCGTCAACGGCTCGATCAGGGAGCTGTACGAGACCGATCTCGGCGACGCTTATGTCGGCGCGATCGAAGACCCCGGTTTCGACCGCCACGACAAATTGCGGATGGACAAGTCGGCGGTCTATTTCAACTCCGGCATGATGCTCATCAATCTCAGGAAATGGAAAGAGACCGGTCTCCAGCAAAAGATCATCGACTTCATTGAAAAACACCCGGAGGACATCTGGTTTCCCGACCAGTGCGGCTTGAATTCGGTCATCAACGGCAGATGGAAAAAGGTGGCGCTGAAGTTCAACCAGTTTTCATCGTTGTTCGACGCCGACTTCGAAAGCCGGTTCGACTGCTTCGGCAAGGAGGAGCTTCAGGAGGCCCGGACGAAACCGGTCGTCATTCACTACACATCGGGATCGAAGCCCTGGCACTTCAAAAACAGGCACCCGTATAAAAGCTGTTACTGGAAGTATCTGAAAATGACGCCGTACCGGCGCGCCATCTACTCAGACCTGAGACCGCTGCATCTGTTGAAATCGATGATCCCGAAGGAGTTCAAGACCGCGATCAAGAGGGTGCTGAAAAAACAGGCCGGTTGACGCACGAAAGCCATCCTGCTTTCGTATCGATGGCAAACAGTTCTGAATCCGCTGTCATTGCAAAAAGCGTCGCGACGTGGCACTCCATGTGGATTCAGCGAAGGCTGCAAAAGATGGATCGCCACGTCCCGTCAGGTCGCGCCACGCGATGACGAATCTCCACCACTGGAGGTGCAGACTGACATGGTGAAATCAAAAAACACTGGACTGATACAATCATTCGTCTGTTTTGCCTTGACACACCACCACCCACTATGAGTCATAAGGAAAACGCGCAGAAAAAGCTTGTCAGCAACGCGGTATCGGGCATTCTGGCCACCCTCGTCTATATGCTCAGCCGGTTGCTGCTGACGCCGTTTATCCTGCACTACCTCTCGTTGAGCGAGTTCGGCCTCTGGTCGCTCTGCTTCATCATCCTCTCCTACGCGGGCATGGGCGGTTTCGGCGTGAACAGCACCTATATCCGCTATGCGGCGCGTTACCTCGCCGAGGGGCGGGAGGAGGAGATCAGCCGCCTGCTCTCGACCGGCGTGGCCTACATGTTTCTGTTCTGCTCGCTCTTTTACGCGGGCCTCTCGCTGGCGATGCCGTTCCTGATGGTGCGCTTCAACGTCGAAGTCGCGCAGCGGGCGGTGGCCACGACGCTGATTCTCGGCACGGCGATCGTTTTCAGCATTGAGCTGGTGCTTGGCGGCTTCCGTTTCATCATCAACGGGATGCACGAATTCGCCAAAGAGAGAATGGTCACCACGGTTGCCGGACTCGTCGAAATCGGCGCGATCATCGGCTTTCTGGCGCTCGGCTCCGGAGTGAAGGGGCTGCTCTACGCCTACGCGCTGCGGCTCGTGCTCGAAACGCTCGGCTGCTGGTTCATCGCCAAATCGCTGCTGCCATCGCTGCGCGTCTCGCTGCGGCTTTTCAGCCGCGAGCACCTGCGGCACTTTTTCGGCTTCGGCGGCAAGGTGCAGGTACTCGGAATGCTCGGCATCTTCCTGACCGCCATCGACCGGCTCTTCATCACCGCCATTTCGGGGCTTGCCGCCGGAGGCTTGTTCGAGATCGGGCGCAAGCTCCCTTCAGCGGCGGGCGGCATCGCCTCGTCGGCCTTCGGGCCGTTCCTCTCGACGGCGGCGCATCTCGAAGGAAAATGGACGGGCGACAAGTGGAAAACTCCCGCCGAACGCGCAGTCACCTATCTCACGGTCGCGCTGAGCACCGTCGCGCTGGCGGTCGCGCCGATAGCTTTTCTCGACCGGGTGCGCCTCTGGCTGCCCTTCAACAGCTGGATAGCCGCGCTTGCCGCTGCCGGAGCAGGCGTACTGCTCCTCGCGCTGCTCGACCGTTCGTTCAAAACCGAAAACCGCCTGGAGAGCGCCGAGCTGAAAAAACTCTACCTCGACGGCATCCGCTTCACCAATATCATCAACTCACTGCTGTTTGGCTTCCTCATCGCCATGGCCCGCCCGCTCATCGACGTCTGGGTGGGCACGAAATATCCCGGCGCCGTCGAAGTCATGATCTTTCTCTCCATCGCCTACTCGATCCAGCTCTGCACCGGCCCGGTCACGCTGCTCTTCAGGGGAATCGATCGCAACGGGCGCGAGCTCGAATACATGCTGGTGCAAACGCTGCTGATGGTGCTCTGGATTCCCGCCGGAACGATGGCCTGGGGGCTCACCGGAGCCGCTGCGGCCATAGCCGCGAGCATGTCGGTCAGCACGCTCTTCATCATCTGGCGAAGTAACGGCACCTTCGCCATCCGCGTGGGCGAATTTTTCGTGCACAGCGTACTGCCGGCACTGATTCCGGTTTTGCCGGGAGTGCCGATTTACGCCATATCACAGCTCTGGCCGCAGACCGGACGCCTGAACCTGATGATCCAGATTCTCTCGTGCGGCACGCTCTTCGTGCTCTCGAGCGCCGGGCTGCTCTGGAAATTCGTGCTCGACGATGCCGAGAAAGCCAAAGCCCTCGAACTGCTGCCACAGAAAAAAGCATCGGCATGATGAAGGATAACGCTCCGAAAGAGGCGCTGCCATTCGGCAAGCCGAACAAACCGATCGACATCGTCGGCTTCGTCAAGCGGTACGGACTGTTCGTGCTCGTAATCGGCGCGTTCCTGTTCACCCTCACCGTGCCGCTCGTGCTGCTCATCAGCAAGCCCAATTACGAGGTGCACGCCCTCATGAGAATCGACCCGGTCATCCCTTCGGTGATCACCAAATCCGAAGACCCGTCGATCATGAACTACTATTCCGATTACTCAAACACGCAGGCTCGGCGGATGATGGATTTCGACGTGCTCGAAGCGACGGTCAAAAAGCTGACTCCCGATCAGCGAAACGCGATCTTTCCGCCGAACCTCCCTACAGCGACCTGCGCCGAGATTGCCGGTATCATCATCAAGATCAACCCCGTGCCGGGCACGCACCTGATCGACATCAGCGTTTCCGGGCCGAAAAAAAAGGGGCTTGCGCCGCTGGTCAACTCCCTGATGCGCGTCTACCTCGACAAGATGAGAAGAGGCAACGAGATGCAGGACAACGAACGGCTGGTCTACCTCAAAAACGAGCAGCAGGCGCTGACCAACGACATCGCCGCCATCGAGGAGAAACTCAACCTGCTCACCAAGGAGATCTCGACGGCCGATTTCGGAGAGGACAACAACATCGCCAGCAAACGGGCCGACGAGCTTCAGCAGGCTTCGGTCAACGCCTTCACGGAGCGGATATCTTCGGAAAACCAGTTGAGGGAGGCCGAAAAAAACAGCCAGCAGCTCAAAAAACTGAGCCTCGATCCCATGGTCGAAGAGCGGGTGATGGGGGATCAGTCCCTCCACTCCACCAGCTCGTGGACCTACCAGCAGCAGCAGCAGCTCCGCAGCACCACGGACGGCCTGACGCAGAACAACCCCGACCGCATCTACGTCGAGCAGCGCATGAAGGCCATGCGCGACTACGAGAAGAAGTTGCAGAACGAGGTGCGCAACTCCGCAAAAATGATCGTGTACGGCAAGCGCGATTACGAGCAGAAGCGGGAGCTGATCCTGAGCAAAAACAAGGCTGAAAAAGCCAAAAGCACCGAAGAGGAGCTGCTGAAGGAGCTGGACAAAACCAGGCAGGAGTCCGTGCGCATCTCGCTCGGCCTGCACCTCGGAGAGGCGCTCAAATCGTCGCTGAAGCACAAGCGCGACCTGCTCGACCAGATCGACACCCGCATCCACGAGCTCGAACTCGAAGGCAAAGCGCCGCTGCACGTCGCCATTGAGTCGCTGGCCCGCGAACCCGAAAGCCCGGCGGGTTCCAACACGAAAAAGCTGATGCTGGTCTTCTTCGCCATCTCGTTCGGCTCGGTCGGCGTGCTGTTTGCGGCGGTTGATTTTCTCGACAACCGGATCCGGCGGAAGGAGGATATCAAGGCGGCGCTCGGCTATCCTCCGGCAAAAGAGATTCCCGAATCCGCCGAAAAGAAGCCGCTCCTCGACGTGCTGGAACTCGCGCCCGGCGACCCCGCCGCGCAGGCGATCCGGAGCCTCGCGGTGAAACTTGTTCACGAAAACCGGCAAAGTGGCTCGAAGATCATTCTCTTCAGCGGCGTCGAGCGACAGACCGGCGCAACCTCGCTCGCCTGGAACTGCGCGCGGGCACTCGGTTCGCTTGCACCAAAGGTGCTGCTGATCGAAGCCGCCACCAACGCGCCGCCGCTCAGCAAACTCAACGGACTCGCCAAGGAACCCGCCGGAGTGCGGGAGCTGCTGGCGGGCACGAAATCGCCTGAAGAGGTGATCGTCAGCGGCGGCGAAGGGTCGCCCGACATGCTTTACCACGGAGAGGCAGCGGCGGGCATCACGCCGCAACAGCGCCTGCCCGGAATACTCGCCGCTCTCCGGGAGCGATATGACTTTATCTGCATCGACGCGCCGCCGGTGCTGGAGAGCAACCTGACCGAAAACCTCGCGCTCCATGCCGATATCGTCACGCTCGTCGCGCTTGGCGAAAGCACGATGTACCGCGACCTGCGGGCCGCCGCCGAGGTGTTCGTGCGGCTGGAGGTTCCGGCGATCATGCCGATCCTGAACTGGGGCGGCCCGGCCAAAAGTTCGACCATCGACAGGCTTCTCGAAAAACCGCCGGAGTTTCTCGACAGAATAGAAACCGGAAAACTCGAAGCGCTGCTCCGCAATCTCCCGTCAGGAGACCGCCTGTTCGACCTCGCCGCCAGCGTGCTCGCTTCGCTCAAAAAGGCGGCCAAACCGAAGAAATCGGGGCCATCCGGCAACAGACAACGTACAAATCCGTGACACCGCCATGAAACACCTGCCGGTTCTGTTTGGCTACCACGCATCGAATCTCGGCAACAGCCATGTGCCGCTCTCGCTGTGCCGCTACTGGAACGAATCGGGCCGCCAGGCGACGCTCACCGTGGCCAGCGCCGATGACGCCTTCGCGTTTCCGTGGGTCACTCCTGCCCTCAAGGGGATCAAAAAAGGTCTCGTCTACAAACTGGGAGAGCGGATGCAGCCGAAGCAGATGACTGAAGCGCTCTTTTTCCGCAAGGAGAGCGCCTCGTCGCCGGTCTATCTCTGGGCCGGACTCTCGCTCGACATCTTCGAGCGCTTCAGCGAACGGGGCGCGAAAATCGTACTCGAACGGATCAACTGCCACCGGGCGACCTCGCGCCGGATCATCCTCTCCGCCTGCGAGCACTGGAACGAGCAGGTACCGGAGACCTTTTCGGACAGCCAGATCGCCGAGGAGAACCGCAAGCTCGAACTCTCGGACGCGGTCTTCTGCCCGAGTCCGATGGTTCGGAAGTCAATGCTCGACAACGGCGTGGCTGAAGCGAAGCTGATGCAAACCAGCTACGGCTGGGCGCCCGAACGCTTTCCGTCGATCGACGCGCCGCGCAAGGAAAATGCGGAGCCGGTCTTCCTCTTCACCGGCACCCTCTGCATCCGAAAGGGCGTTATGCTGCTGCTCGAAGCGTGGAAAAAAGCCAAAATCCGCGGCAAGCTGCTGCTCTGCGGCGGCGTCTATTCGGACATCGAGGCGGCGATGGAAAGGCATCGGGACACCCCCAACATCGAACACATCGCCTACACGAAGGACATTGGCGAGGTCTATCGCCGGGCTGATCTCTTCGTCTTTCCGAGCCTCGAAGAGGGCGGGCCGATGGTGACCTACGAAGCGATGGCACACGGCATTCCGCCGCTCGTCACGGCGATGGGCGCAGGCGCTGTCATGCGGGACGGCATCGATGGCATCGTGCTGCCCGATTTCGACGTCGATGCCTGGGCGGCGGCGATGACGGAGATGGCGGAGAATCGCGAGAAGAGAGCTGAGATGGGGCGCAACGCACGCCAGCGCGCGGCAGAGTTCACCTGGAAGGAGGTAGCAGCCCGCCGCGCCGGACTGCTCGAAGCCCGCTATCCCGAGCTCTGGAAATGACAACCGGTCAAACGAGGCGATGAAGACAAGCGACAACACCGCGCCAATTTCGGCGACCGAACCGGACTGGAGCCGCGAATCGCCGGTTCCGGGGCGATACGAACCGGCAAAAAATCTGCTCGCGGCGTTCCGGCGCTATCAGCGGCTGAAGGCAAAGGGCGGCATCATGGCCCGCGCCCTGCGTCCGTTCGTGGTGCTGCGCCACCGCTTCTGGAGCGCGGTCACGGGCGCGGACATCCCGCTCGACTCGCACATCGGCGGCGGCTTGCTCCTGCCCCACCCGAACGGCATCGTCATACACCCGGAGGCGCGGATCGGCCCGAACTGCCTCTTTTTCCAGCAGGTGACGATCGGCATGGGCGGACGCAAACCCGGCGCGCCGGTGATCGGCGGTCACGTCGATATTGGCGCGGGCGCGAAGATTCTCGGCGGCGTCACGATCGGCGACCACGCCCTCATCGGCGCCAACGCCGTCGTGCTCTGCGACGTGCCCCCGCACGCCACCGCCGTCGGCATTCCGGCAAGAGTTATCGCACCGAAGAAAAGTTGACGATATGTACCGAGCTATAAAAGATGTGGATATTCTGACAGAAAGAGATTGGGCTAAAGCCCAGAATAATTTTGTTTTACACGCATACCCCGGACTAAAGTCCGGGGCAATTGTCAAGAGTCTCAATTGTCGAAACAGTATGGAACCGCAAGAAAACGCATTCCGGTCGAAAGTTCTCCCGGTTCCCAGGCAGCGGCAAAACGGACGTGCCCCTCATGCATGAAGGCGAGGGAAATATCATGGTGGCCGTCGCCCTGTTCGGCTGGATTCCGATTGTCAGGGCGATCTTCAAGCGCTTCGACGCGCGGACGGCCGTCGCCATCGCCTTTGTCGTCGGCTGGATGTTCCTGCCTGTCGCCGGGTTCAAGGTCAAAGGCATTCCCTCCTACAGCAAGCTGACCGCCACCTGCATGGTCATTCTGTTTTGGGCGCGTCATTTCGACAAGGAGCGGTTTCGGGAGTTCAGCTTCGGCCTGATCGACCTACCAATGCTCGCCTGGTGCGTCTCACCATTCTTCTCTTCGGTCTTCAACGACCTCGGCGCTTACGACGGCCTTTCGCAGACCATGTACCAGAGCATCACCTGGGGTGTGCCCTGGTACATCGGCAGGGTTTACTTCAGCAACGCCGACGGGCTGAAGCTGTTCGGCACGGCGATCTTCATCGGAGCGGTGGCCTACATCCCCTTCTGCTGGTTCGAACTCGTCATGAGTCCGCAGCTCCACCGGTTGACCTATGGATTCCACCAGCACAGCTTTCTCCAGACCCTCCGGGATGGCGGCGGATTCAGGCCGATGGTCTACATGGATCACGGTCTCATGACCTCGACGTGGATGGGGCTTGGCCTTTTTCTCGGCGCGTGGCTCTTCTACACCAGAGACCTTCCGGAAAAAATCCTGGGCTTGCCATCGCTTTATCTGCTTCTGGCGCTTGGTGTTACCTTTCTCATGATGAAGTCGTACGGCGCGATTTTCCTGATTTTCCTGGGCCTCGGGTTCGTCTTCCTGTCGAGCAGGATGAAAAAAAACTGGCTCGTCGTGCTTTTGCTCGCCGCGCCCCACCTTTATGTCTACACGCGGACGACCGGCATCTGGGACGGCACGAACCTCTCCGGCTTCGTGGCGGAAAAGTTCAGCCCGACACGCGCCCAGTCGCTCCAGTTCCGTTTCGACAACGAAGCGATCCTCATCCAGAAGGCGCTCGATGGCACGGTGTTCGGCTGGGGCGGATACGGGCGGTCGCGGGTGTACGACGAATACGGCAAAGACATCAGCATCACCGACGGACTCTGGATCATCACCCTCGGCCAGAACGGCATCTTCGGCCTGATGGCCCTGATGTTCGCCGTGCATACTCCGGTGATCTTCTACCTCATGCGAAGCGATCCGGAGCGCTGGAGCGAGAAAAACCGGGGCGCGCCCACGGTGATGATCGTGTTTCTGTCACTCTACATGATCGACAGCCTGCTGAACGCCATGGTCAATCCGGTGTACATGGTTTTTGGAGGCGGCATCGTCAGCATGTTGCTCAAAGGCGAAGCGGCGTTCAACACGGAACCGGCGGACGGCTCGATCGAGGAGGCGCGGATCGACATGCCGAATACCCGCTTTCTTCCCTCGCCCTCCTTTCAAGGCTCTTCACGTTTTATCAGTTGAAAAAATCGAGGCATGAGTACGGCAACTGAAAAATATTCCGAGTCCGGATACTGTTCACCTTCCAGACTCGGAACCTTGTGGATTGCAGCATTCATCCTGGCGCTGGCGGGCGCGTTCGTGCCGAAGCCGGACTTTCGCTACGGCTTTTTCATGATCGACACACTCATCCACCTCGCGCTTTTCGCTATCCTCGCGTTCATTCCGATGATCTTCTTCCGGTGTCGAAAAACCACCTTCCTGCTCGCTATTTCGATGGCTCCGCTCGGTTACCTGCTCGAAAATCTCCACGTGATGGTGACCGGCAGCAACTTCGACACCATTAACGCGCTGGCCAACAACCTCGGCGTCCTTGCCGGAATCGCCGCCGGATTTGTCCTGCGCCTGAAAAGTCACTACCAGCGGAAACGTCAGTCATAAATTTTTACGAAGATGAAAGTCACCGAACTGGCCCGCATGGGGCTGAACCATAGCCGCAACGCGCTTGCCGAGTCGCTCTACATCAACACCGGCGTCGATTTCACCCGCCCCGTCACCTTCCACGCGCTGGTGAATGAGCGGTGCAACTGCAAGTGCCGCCACTGCGAGTACTGGCGACAGGCGGAGTACATCCCGGAGATGTCCATCGAAGAGTGGCAGAAAACCCTGCTCAGCATCAAGGAGTTCGCGGGACGCTTCTCCGTCAACTTCAGCGGCGGCGAACCCTTTATCAAGAAAGGCTTTATCGACCTTTTGCGCTTCTGCCGCGACAACGACATTCTCGCGGGCGTGACGACCAACGGCGCGTTGCTGAACGAAAAGAACGTGCAGGCGCTCGTCGCCGCGCGTCCGTTCAACCTCAACATCTCGCTGGACTCGACCGACGCCAGGGTGCACGACTACGTGCGCGGCATGAACGGCCTCTTCGAGCGAATCGTGCGCGGTATCGGACTTCTGAAGGCGGAGCAGCAGAAGCAGGGCGTCACCTTCCCGATCATCATCAAGCCGACGGTCATGTCGGCAAACTTCCGGGAGCTGCCGGAGATCGTGCGCTGGGCGGAGAAGATCGGCGCGACGGCGGTGAACTTCCAGCCGCTCGGGCGCTGGACGCCGGAGACGTATGACGAGTTGTGGATCGAAGAGAAGGAGATGGCAGAATTCGAGGAGGTGATCGACCGGCTCGTCGAGATGAAACGCGCCGGATCGCCAATCATGAACAGCGAGGAGATTCTGCGGCTCATGCCCGCGAGCTTCCGCGAAGAGAAGGCGTCGCCGGAGCACCTCCCCTGCCGCATCGGGCTGCACGAGTTCTACATCCGCCCCGACGGCGAGGTGAAGCTCTGCTTCCACTTCCCCTCCATCGGCAACACCACCAAAGAGTCGGCGCGGGAGATATGGACGGGCGCGAAAGCGAAGAAGATTCGCGAAGCGACGATCAAGTGCGACAAGCTCTGCCTGCTCACCTGCTTGTCGCAGAAGTCGCTCGTCAACAAGGCGAGCCAGGCGCTGACCATGCTCACCCGCCAGAAAACCAAAGCCGGACAGTGACCGCGCGATGAACGAAAAACGCCTCGACAACCCGGCATACCGGAATGGCCGCGACCTTCCGGAGATCGACTGCGTGCTCATCGGCGTCAACAGCGCGAAGACGCTCGGACGCTGCATCGAGTCGATCCGCTCCGGCAGCTATCCGCCTGAAAAACTGCGCATCTGCTACGCCGATGGCGGCTCGACCGACGAGAGCATCGCGGTGGCGAAACGTTACGACGGCGTGCGAGTGCTCGCGCTGACGCCGGAGTATCCGACGCCGGGGCTTGGCCGGAACGCAGGATGGAAGAGCGGCTCCGCGCCGCTGGTGCAGTTTCTCGACTCCGACACCATCGTCGATCCGGAGTGGTTCCACAAAGCGGTCGCCCGAATGCGTGACGCCCGCGTCGGCGCGGTCATCGGCTTCCGCCGCGAGCTGCACCCGGAGCGCTCGGTCTACAACTGGATCGGCGACCTCGAATGGAACGGGCCGGTCGGCGAGTCGGACTGTTTCGGCGGCGACGTGCTCCTGCGCCGCGAGGCGCTCGAAGCGACCGGCGGCTACGACGAAACGCTCGTCGGCGGCGAAGACCCGGAGCTGAGCCGCCGCGTCATCCGCGCCGGATGGAAGATCGAGCGCATCGACGCCGTCATGACGCGCCACGACCTGGCCATGACCACCGTGAAGCAGTACCTCAAACGCGCCTACCGCTCCGGCTACGGCTTCGCCGCCGTGCGAGCGCGGGAGGCCCGGCTCGGCAGCCCGTTCTGGAAAGCGGATTTCCGCAAGATCGCCATCAAGGGCGGCGGCTTCATCGCCGCGGAAAGCCTGGCGATGGTGACGCTATTCGCCGCCCGTCCCTCGCTGACATCGATGCTCGCGTCGGCGACAATCGGCTTGGCGGGAGTGCCGCTGCTTTTCTCGCCGCGCCTCTTCAAGGTCGGCAAGTTCATGCGGGAGAACCAATTGGGCCGCAAGGAGGCCAAAATCTACGCCTGGCACTGTTCGGCGGTCGTTCTCCCGCAGCTCGCGGGCGTCGCGCGATACTATGCGGGTGCAATCGCCGGACGTCCGCTGAGGAACAAACGAAGCGCCCTGAAAACCGGACTGTCGCAGCCCGAAACCTGACGCCCGGCCACGCCTCCAGCACCGCATTCGACAAGATTTCGACAAGATTCAGATAACCATCCCCTCGCCCCATGCCGATAAACCTGCCCTATCTCCGCCGCTCGTTCTGGCGGCTGCTCGGCAACGGCTCCTTGCCGGAGCTGTGCGAAAAGGAGTGGATCGTCGCCCCGGCCTGCGTCACCACGACGCGGCCCGCGCTCTACCTGCCGGGCGCACTCGATAACGTCACCGCGTCGTCGGCTTCCTCGAATCTGGAGCAGGAGATGCGGAGGATCAAGGGCGGACGCACGGAACACGCCGCCACCATCGCGCGGGCGCTCGCAGACGTGACGCTCTCTGACGGCTATCTCTACAAGCGAGGCCTCAAGATTCCCGTGCGCATCAAGAAAGAACAGCTCGTCATCGAACGCCAACCGACTGCAAAAAAAGAGGTTGCGGTGCTGGCGTGCGGGCTGACCGATATTCAGTTCTTCGGCCACTGGATGACCGACGGTCTTCCGCTGCTCATGGCCGCCCGCGATCTCGGCCCGCCGATTCGCAACACCGCACCACTGACCGGCCATCAGAAGGAGTATCTCTCGATGCTCAATCTTGGCTACGACCCCTTCGCCGCCGGAAAGATCGGAAAGCTCATCGTGCTCGAAGATTACGGCCAGAACAACTACAAGCGGGAGCGATACCAGGCGATGCGGGCGCGCTTCCGGGAGGTCGCGCCGAAACCCGCGCATCCCGGCTCGCTGCTCTTGCGCGGCACCTCCGGAGTGGTCACGCCCGACGCGCAGGGCAACCGGCGCATACTCGTCAACGAGGAGGAGATCGCCAGCTACCTGCAATCGATCGGCTTCCAGCTCATCGACTCGACGAAGCAGAGCGCCAGGGAGATCGTCGAGAAGACCTCCGGCTCGAAGATCATCATCGGCGTCGAAGGGAGCCAGATTCCGCACGGGCTCTTCACGATGGCCGACAACGGCGCGCTGATCAACATCTTTCCGCCGTTCCATTTCAACAACGTGCTCAAAGGCCAGACTGACTGCATGGAGATGCACTACGCCTTCACGATCGGCGAGGTGTGCGAGGGAGGATTCCGCCTGCCGCTCGACACGCTCAAAAAAACGCTCGACCTCGTCGCCGCAAAGACGGCCTGATTTTCGAGAAACGATTCCGAAGCATCCGTCATTGCGAGCAACCCGTATCCGGCTCGATACCGCAGACTAACCTTGAACATGATTACCCTGGAAGCCCCTGTCATTTCCAACGGTAGGGGCAGCCCTTGCGGCTGCCCTTTTGCGCCAAAGCGATGACAGCTTTTCCGTGACAATCAGCCATACCGCGTATGTTCATGGAAAGGAGCACGCGACGCGGCAATCCATACGGAACACCACTGATCGGCGCCATCACCCGCTCAAACCAGATTTTCAACCCCCCAACCCATGACCCGGAACACTGTCGCCTATCTGTGCAGCGAGTACCCGGCCATTTCGCACACCTTCATCTACCGCGAGATCGAGTCGCTGCGCAAGGCCGGAATGACAGTCTACACGGCCTCGATCCACAAGCCGGAGAAGCTCGACCTCATGACGACCGCCGAGCAGGAGGAGGCGGCAAACACGCTCATGGTGCTCTCGCAACCGGCAACAGCGATCATCGCAGCGCATCTGCACTGCCTGGCCAGAAACCCCGGCGGCTACCTGAAGATGGCGGCGGACGCCTTCCGGTTGCTCTTCAAAGGCCCGAAAAACTTCGTCAAGGCGGCGGCCTACTTCGCCGAAGCGGGCATCCTCTTGCGCTGGGCGCACCGGCACGGCATCACGCACATCCACGAGCACTTCGGCAACCCGACGGCCATCGTCGCCATGCTCATGAAACGTTACGGTGGCATCACCTTCAGCATCTCGGTGCACGGCCCCGACATCTTCTACACCGTCGATTCCGCGATGCTGCCCGAAAAGGTACGCGAGGCCTCCTTCGTGCGCTGCATCAGCCACTACTGCCGCAGCCAGATCATGCGCATCAGCGATGTGGAACGGTGGGATCGCTTCCACATCGTGCGTTGTGGCATAGATCCCGAATTGTACACGCCACGCCCCGAACCCGCCAACGCCGTGCCGGAGCTGCTCTGCGTCGGGCGACTGACGCCCGCCAAGGGGCAGCACATCCTCATCGAAGCGTGCGCGATGCTCGACAAAGCGAACGTGCCGTTCCACCTCACCTTCGTCGGAGACGGCCCCGACCGCGAGTCGCTTCAAAACTATACACGGACAATCGGTCTCGACCGCAAGGTGACCTTCACGGGCGCGCTTGGGCAAGACAAGGTGCGCGGCCACTACGACCGCGCCGACATTTTCGTGCTGGCGAGCTTCGCCGAGGGTGTACCGGTCGTGCTGATGGAGGCGATGGCCAAGGAGATTCCGGTCATTTCGACCCGCATCACCGGCATTCCCGAGCTGATCGAACACGGAGAGGACGGCCTGCTCGCCGTGCCGGGCGATCCCGAGGATTTAGCGCGCCAGATACGTATCTTGCTTGAAAACGGTGAGTTGCGCGCACGCTACGGGCAGGCCGGGCGGCGAAAAGTGAGCGCCATGTACAACCAGCACCAGAACAACAACCTGCTGGTTGAGCACTTCAAGAACGAACTGAACGACGTCTGATGCAGATCATCGTCCCGACTGTCACGCTGCTGGTTATTCTCTTGTCGCTCCCGGCAGCCTATCTTTTCATTGTCACCGTCGCCGCGTACCTTTTCCGGAAAGAGGCGCTGGCGGCGAACCGCATCCTCGAAATCGGCGTACTCATCCCGGCGCACAACGAGGAGGCGGGCATCGTGGGCACCATCGAGAGCATCCATGCGAGCGACTACCCGGCGGAGAACGTCAAAATCTTCGTCATCGCCGACAACTGCGACGACACCACCGCCGAGGTGGCGCGAAACGCGGGCGCGACGGTCGTGGAGCGATTCGATCTTGAAAACCGTGGAAAAGGGCAGGCGCTCGACTGGTTCCTCAGGAAACACAAAGAGCTGAACCATGGCCTCGACGTCATCACCATCATCGATGCCGACGTCCGGGTTGATCGCAACTACCTGCGGGAAGTGAGCCTCTCGTTCAGCCAGCCGGGCATCCAGGCGTTGCAAGGCTACAACGGCGTCAGCAACCCCGAGGCGGGTTGGCGGCCCGGACTACTCGACGCGGCCTTCAACGTCTTCAACCACCTGCGCATGGCCGGGCCGTTCCAGCTTTCCGGAACCTGTGCGCTAAAGGGCAACGGCATGGCGTTCGACAGATTCCTGATCGAAGAGACCGGCTGGCCCTGCCACTCGATCGTGGAGGACATGGAGTTCAGCTTCCTGTTGCTCATGAACGAGATCAGCGTGCACTACAATCCGGACGCCATCGTGCGGAGCGAAATGGTCACTTCGGGCAAAAACGCTTCGAGCCAGCGCAGCCGCTGGGAGAGCGGGCGCTTCAAGCTGGTCAGCCAGATGGCTTTGCCGCTGCTCAGGCTGTTTTTCAGCACCGGCCAAATCCGCTACCTCATCGCCTTCGCCGAACTCGCCGTCCCCCCGCTCACCCTGCTGGTGCTGCTTTTCGCCGTCGCATCGCTGCTGGCGCTCACGCTGCTCCACGGCGCATGGCTCCAGATCGTCGCCGCATGGTGGGCCATTCTTCTCTTCTACGTAGTATCGGGCCAAATCCAGCGCCACGCTGGCCTCCACACCTGGCGCGTCCTCATCGCCGCCCCCCTCTACATCCTCTGGAAAATCCCCCTTTACCTCGCCATGGCAATCCGCAAAAAAAGCGACGCCTGGGTGAGAACGAAGCGGGAAAGCGAAGCTTCAGAACCGGAGGCGTAATCGCCACTGTACCGGATTCTCTCTGACACCGCTACGCCCGCTTTTTTTCTCCCTGAAAGTATCGGCTCCGAGACAAGCCGGTTAATAACTCGCTTCTACATCAGTAATAAGTCGGCAGGATATTGCCGTAAGGATCGATCAAGCCAGGTAGAAAACAACTTCCGGCAACAACCCTGCGACTTGCCGGGTTGTTGTCAATTTCACTGCTCTTGATTAAACTTTAAAATATAGTTTTTGACACTACATATCAGCCAATCAGGTATAATAATTATATACACCTGCTCTAAACCGCAGCCTGACAGCGATTCCCTGTCAACACCTGCCAAACGGGAAGTGGAGCCACGATAACAACTCCCGGAGAACCGATTGATTGCAAATGAGATTATCGAACAGAGAAGTATAGCGACGGTATCCTGAAGAAAACATGAATGATTCAAGGAGGAGATTATGTCCAGAATCGCGGGTATTGAAGGGATTGACGAAGTGCATGTGGAAAAACTCCACGGCATGGGAATCACTACTGTTGAGGTATTGCTTGAAAAAGGGGCTTCTCCGGCAGGAAGAAAAGCCATCGCCGATGCAACCGGAATGAGTCATGCGCTCGTGCTCCGGCTGGTGAACCCGGCTGATCTGTTCCGCATCAAGGGCATCGGAAAGGAGTATGCCGACCTGCTGGAGGCCTCAGGCGTGGACTCGGTGCCTGAACTGGCGCAGCGAAGAGCAGAGAATCTGCACTGTAAAATGTCTGACGTGAATACCTCGAAAAATCTCGTAAAAAGATTGCCGACCGAATCAGAGGTAGAGGAGTGGATTGCACAGGCCAAATCTCTTCCCAAAGTAGTGACGCATTGAGCGATCGAAGAGAACCGGAGGGCGCTTTGGCAACCTCAAAAAGACACCATCCACGACAGCCTCGGCAGGAAAAATGCCGGTTCAGGAATTATTGCCAGAAACCCTTGCAGTCATAATGAGTTAAAAACGCATGAAGCCGGGTGCTCCCCGGCTTCATGCATTTCAGATCGAAAAAACTCCCCTCAGTGCGGCAGGCGGTTGAACTCGTTGAACAAAATGGCGCGGGCGAAGAGCGTTTTTGCACGACACTTTTCCCGTCTTGCTGAGTGTGGCGGCAAAAAGAACTGCCTCACTCACGCCACAATCGCGATGCCTTCGCCCAGGTCGATGGCTCCGGGCAGGTTGATTTTTGTGGATTCTTTCCGGTACAGGCAGGTGTTCATGCAACAGACACTTCCGCTTCCCTGACACTGCCCGGCAAAAATTTTCATGATTTTTCCGGCCTGTATTTCAAGCATGAAGCCAGAAAGAGAGAATTCTGTCGTTATGGTAAACGGAATGTTTTTTTTGAGTCGCCTGCTGAATTCGACCTCGATGGAGGGCCGGTGGATGGAGGTTATGGCGTGCTCCATCAACGGAAGCACAACCAGTTCGTCAGGCGAATAGCGCTGCGGGTCGGCGTATTTCGCCAGGTCTTCATATTTTTCCCACGCACGCAGCAGAATATCTCGCACCTCGATGCCGAGCAAATCATCCACATGACCGATGACGGCCCTGATCAGCGCCCTGCTTTTGCGGGAATGGCGATCACCGTCATTCGTGTCGTGATCGAGTTCCCTGACCTCTTCTTCGGAATGCAGCCCGCTAACGGCCTCTTCGCCAATCGTTTCATCCCTGAAAAAATCCCTGAGCGTAAAGGATTTCGAATCCATAAACCATTTATTTAATTGGCATTCCGGTCTTTGAAACGGATTTTCTGAACACCCGGATCGTGCCGTAAACTCAGTCTGAAACCGTTGCCGCCCAACAAACCGGAGGGCGCCGTGAACTGCTGCGAACCGGCGTCGGAGTGAACCGCGACCTTGACTACTGGTTTGGACTTGTACGCCATCGCCGCTCCCCCACCTCCGGCAGCAAGAATCGTGGCGAGAATCATGGCCTTGACCGGAGCCGGAGTCTCCATGTAAAGATCGACCTTCGCGCCTCCCGGATGCCTGCGCTCCGGCTCCGGAATCTGCCTCGCGACAACGAGTCGAGACTGAACGAAACCGGGCGCGTACTCTCCGATGAAATCCCTGCTCACTCTGCCAATACCGAAACCGCTGTCATTCAGCTCAATTGTCGCACGGCTCAACGATTTACCGATGACATCCGGAACGGCAACCAGACTGCCCGCCGGAGCGCTCCTGCCTTCTTCACTGATATTGGATTCTGGCTCGATATTCTGTTTGGAAACAGGAACTCTTTCCGGTTGGGGCGGAATAGAATTAGTTGAATGACGGTGAGGTTTGCCCGGCCTGTTAGGAACTGGAGGATTGACGGCGACTTCCGGCTCGTTGCGAGGCGTGGAATCATGGCCCGGATGGTGAACAAGCGTCGTGCAACATCCGGCAAGGAGCAGAATCATGACAAGTGCTGCAATCACTCTTTTCATATCCATGACTCTTTGCGTTTGGGGTCAACGTATGAAGCCGACTGGAGATAAACGGAGAATGGGACACCCTTCGCTTCTCTGAATCAGTTTAGGTATTTCCAATCTGACAAACAATCTGAATACCTGTATTTTCTCTATTGACTTCATGGTTTCGGCGGCTCTGTCCGATACATTTACAGAGTGCCGGTCAGGCCCGACAAAAACAGTTTAGAGATTCGCCTTTCGTGAAGTGATTTTAAAATCTAAACATACACGATCATGGACTTATCAAATCTCCTTCAACTTGGAGCTTCCACCATTCTGCATAACAGCGATCAGGCGACCAATGGCCTTGACAGCAATGAGCTTGTTTCGGCGCTGTCAGGCCTGTTGGGCGGTGGCGGCGGCAACATGAATCTCGGCGCTATCCTCTCCAAAATGCAGCAAAGCGGACTCGGCGACATCGCGGCCTCCTGGCTCGGCAATGGCGCGAACGCGCCGATCTCGCCCGGGGCGGTGACGGATTTGATCGGCAGTGATAAAATCGCCGATTTCGCCTCCCGCTTCGGCCTTTCCGAGGAAAGCGCCAAAAACGCAATCGCCAGCGCCTTGCCGGAAATGGTGGACAAGGCCAGCCCGAACGGCTCGCTGCTCGAAGGTCTCATCGGCAATATCAGCGGGCTGGGCGGACTGTCGGACATGGTAAACAAGTTCTTCTGAACCATCACCACAGCACAAACGCATGAAGCCGGAGAACATCCGGCTTCACTGGTTTTATGACGAAACCACGCCTCAGAGCGGCAGATTCTTGCACTCGTTGAAAAAGTCGCGCAGGCGATGAGTGCCGTACTTCGGCGAAACGAAATCCATCTTGCTGAGCGTGGTGGCGAAGAGCGCAACGTCGGCAACGTCGCGGTTGAAGATGCCGACGACGCCGACGATGCCATCAGCCAGCCAGAAAGGCAGCGGAAGCTGAACCGGCTGCGTTCCGGCGATTTCGATAGCCAAATCGACCATTTCGCGGTAAGTGAAGACCTCCGGGCCGCCGACCTCGACTTCGCGCTCGCTGCTGTCCACCGCGTCGGCGCACACCTTCGCGAGGTCAGCGCCGTGAATCGGGTTCTGGCGGTTGTAGCCATCGCCAATCCAGAGCATGAATCCGCGGCGGGCGCGGGCGACGAACTGGCCGATCTCGGAGAAGAAGCCGTTCGGGCGGATGATCGTGCTCTCGATCTTCGTGGCCTGCAACTCGCGGACGAACTTTTCGTGCGCCTGCACGTTCGGGATATTCATCATGCGGTGGGCGTCAAACACCGAAACATAGACGAACTTCTTCACGCCAGCCTTGAGCGCCTCGGCAAGGATGTTCATGTTGCCCTGATAGTCCACGTCGAAGTTGTCGTGCTCGAAGTCGGGCTTGATCATGCCGAGCGACGAAAAGACCACGTCGATGCCGTCGCACAGCCCTGCGATAGTTTCAGGTTTCGTGGCATCGCCGAAGACAACTTCGTCAACGAGCGTATCGATCTGTGGCGCAAAAAACGGCCCCGGCTTTTTGAACTTCTCGGGATTGCGCACCAGCGCGCTCACCCAGTACCCGCGATTCTTGAACTCCTGCACCGCATAACGGCCCAGGTAACCGGTCGCCCCGGCCACAAGCACTCTCTTCATTGATTACTCGGATAGGTTGATGGATAAAGCTTTTGCGACGGGCAATATACGCAATTCAGACGAGGGGCGGAGCAGGAGGACTCCCGATCTCACAGCCGGAATCGGGAGACGCAGTATGCCTTCGCTATCGATAAACCTCTCTTCGGTGGCCGACGGTGACAACAAGAATGATGAGTTCTGAGTCTTGTATTTCGTAAATCACCCGGTACGAGCCTATGCGGATGCGCCATGCCTGCCGTCCCGACAGTTTCTTGCTGCCGGTAGGACGCGGTTTTTCAGCAAGCGAACGGATGGAATCGATAATTCGATTACGATCAGACTCTTGAATTTTTTCGAGTTGCTTCCGGGCCGAGCGCAAGATTTCGATCCTGTAGCTCATGATTCAGAACCTTCGTCAATCTCCCGCACAGCCTGTTCAAAAGGCATGATTTCCTGAGAACCGGTCTTCGCCTCGTCATAAGCGTGAATGTCATCGAGTTCTTCGAGATAGTCGAGAATCTGCTCCCACTCTGCCAAAGGAAGCAGCACTGCCGTCCGTTGCTGGCGCTCATCGACCACATACTGCGGATGAACCTTAATCATTGTATTAGCTCCAAAACTGTGGTTTTCGCTGAATTCTTCTCCAACCGATTATCTGACAAGTGCTTGAATTCAGAAATCTTTCAGCACTGCATTCATATTCTGCTTTAACGTGCCTTCCAACCGTTTGCAGCCACGAGGAGAATAGTCATAAAGAAGCACTCGACGATGCCTCAGATCAAATGGGACATCATCGATAGACTGCGCAAGCAGAAGAACCGGCTTTCCTAAAGCATGACAAATACCAACCTCGTAAAACACGTTCGCGTTCTTCCGAGTAAGGTCTGCAAGGACAACATCTGCTGTGCCGATGCTCTTGAGTATGTCCTCCATAATAATGTTGGAGCCAAAAACGTCATCGCCGCGTTCGCAGTGCAGGTTGCAGCCATCAACAAGTGTCGGCTTTACAAAATCCTCATAGACTACCTGTAAGTCTTCATCACCAAATGGCATGACAACAAAGCATCGCATCTTCTCTTCTGGAGCACGTACATGCTCCGTGAATTGCTGATGCGGCAAAGGTTCAGCGGCGCGAGACTTGAAAAGTTCCACCGCCTCCTGAAGCTGATTACGAAGGCTCTCTACTTCGATAGGGTCAACAGCCTTGATGGGAGCGCCAGGCACTTCGCCCTTTGCTGCCTTTGGCCGTTTACCTGTTATTCCCCAGATGAGGTTAGCCAGCCCAGCCCCGTAGTCTTCAGTAAAATCTACCCAAGTAAGCTGAGACAAAAAGCCTGTCGGGTTGCACGGTCGAATCAGCAATGGTAAAAGGAAGGATTCATTCTTGAGCTGGCGCTCAAGTGCCACGTTCAACTCTTGTTCCGCCCATGCTGACGCCAAATAGTCAGGAGAAAGTACTGCTAACACAATGTCCGCTTGCTCGATCTGAGATGCAAGTGTTTCAGCCCAAGAAGTTCCGGGTTGAATGAGCATGTCATAAAGAACCTGAGCATCAGGCAAATTCACATTGAGATCGTTGGTAAGCCGTTTAACGAACTCTCGATCCTTGTGCGAGTAACTAATGAATATCTGGCTCATCTCGTTCTTAAGTTCTTATAAAATTAATCAACAGCAATTCGATAAGTTTACTGACTACAGATATTGCAACTACAATTCAAAATAATAGATAAAAGCAACAATATCAACGTCTTACAAGTCCCATCCATCACCGAAAGCGCTTCGACGATCATGCCGTATTCGACCGGGTTCACTTTGACGACCAGCCCCGCCTGCTCCACGGTCGCTTCCGGAGCTACCGAACTCTGGAGCGAAACGGTTTCGGGCGCTCTTGACGTTTCCTCTCTTCCCGCTTTCCCAGCCGTCCTTTCCAACAATTTTGCACGAAAAACATGTAAAGTTCAGGCGCAAGTACGCAAATTGCGCCAAGACATTTCGCTACGATCACGCGAAAAACGGACAAAATTTTCAGGAGTATCTCATGAAATTCGAATATCATAACACCACGCACCTTGTTTTTGGAGCAGGCACCCTTTCTCGACTCGGCGAGGTGACCAGCGCATACGGCAAAAAGGCGATGATCGTCACCGGCGGCGGCAGCGTCAAGCGCAACGGAACCTTCGACCGAGCGGTCGCGAGCCTCAAGGCCGCCGAAGTTTCGGTGGTGGAGTGCGACGGCGTCGAGCCGAACCCCCGTCTTTCGTCGGTGGCCCGAGGCGGCGAGATCGCCCGGGAAAACGGATGCGACGTGGTGATCGCGCTTGGCGGCGGCAGCGTGATGGATTCCGCGAAGGTGATGGCTGCGGCAGTCTTTTACGAGGGCGACCTGTGGGAGATGTTCCAGCACAGCCAGAAAACCCGGCGGCTCCCGACCAAAGCGCTGCCGATCATCACCGTGCCGACGCTCGCTGCCACCGGCTCGGAGATGAACAGCGGCGCAGTCATTAGGGTCTGCTGAATAATGGTTAAATTGTTTTATGGTAATGAATTAAGCGGTATTTTTGTATCTTGAATGCAAGGAAAAGCCTGAAAAAGCCCCAAAAACCCTGCACCTCGATACCGCCGATTCATGTACCAGCCGAAGTTTCAGCAGCTCACGTTCGAAAATTTCCATCTGCCGTTTGGTGGTAAACTCGATCCGGAAAACCGGTGGGTGAAGCTCGCCGACGTAATTCCCTGGCACGTCGCCGAGACGATGTATGCCAAAAACTTCATGTCGAAACGGGGCGCTCCTGCACTGACGGTTCGCATGGCGCTGGGGTCCTTGATTATCAAGGAGAAGCTCGGCCTTTCGGATATCGAGACGGTCGAACAGATCAAGGAGAACCCGTATCTCCAGTTCTTTATCGGTCTTGAAACGTACCAGCATGCAGCGCCCTTCGATGCCTCGATGCTGACCCACTTTCGGAAGCGGCTGAAGCATACCGATCTGGCCGCGTTGCAGGAGGAACTCCTGCAACGCCATCTGGCTGAAGAGCGCAGGAAGGCTGAGGAAAGGAACCAGAATGACGACGGAGACGGTGGTTCCGGCAACAAGGGCAAACTCATCGTTGATGCCACCTGCGCACCGGCAGACATCGCCTATCCGACGGATATTGGTCTGCTCAACGAAGCACGGGAAAAGACCGAGAAAATCATCGACCAGTTGTGTGCCAATGCTCCGCAGGAGTTGGGCAAGCCGAGGACGTATCGCAAGAAGGCCAGGAAAGCGTTTCTCTCGGCAATCATGAAGCGGAACCTGTCGAAAAAAGCGCTTCGTCGAGCCATTCGCCAGCAGTTGCAGTACATCGGTCGAAACCTGAAGCATATCGAAGCGCTCAGCGCCGCTGTACCGCTGACCGTCCTCTCGACAGCGCGGTATCGCGACCTGCTGGTGATCGATGAGCTGTATCGGCAGCAACAGGAAATGTACAAGAGTGACAGGAAGAGCATCAGCGATCGAATCGTCAGCATCAGCCAGCCCCATGTCAGGCCGATCGTACGGGGCAAGGCCGCAGCCAGGACGGAGTTCGGCATGAAGCTCTCCATCAGCGTCGTCGACGGCATCAGCCTGCCGGAACGGATGAGCTGGAACGCCTACAACGAAGGCTGCGACCTGGTGCGGGATATCGAGCGATATCGCGAGCGCTACGGGCACTATCCCGAATCAGTCCATGCCGACAAGATCTACCGGACGCTGGCCAACCGGATGTGGTGCAAGGCACGAGGAATCCGGCTGAGCGGCGTGCCGCTCGGTCGGCCCCCGAAGGATGTTGAGAAGAACCGGGCCCGCCGGCGGCAGATCAGGGAAGACGAAGGAGTCCGGAATGCCGTCGAAGGCATGTTCGGTAAGGCGAAGCGCCGATACGGGCTGGGCCGGGTAATGGCGAGGCTTGCCGAGAGCAGTCTGAGTGTGGTCTCGATCACGTTCCTCGTGATGAACTTGGACCGGCTGCTCGCCGCTCCTTTTTTGCGCCTGTTTGAATGGCTCCTTTTGGAGCTTGATGTAATCAGAAATTTGTTCGCGTGGTCACCTCCCCGAGCGGCGATTGAGTGCCGCGGGGCGATGGCTTGAATTCTTCAGCAAACCCTCATTACGGACGAGAAGACGACCATCAAATCGTTCGTCGGCGCGAAGTGCCTCTACCCGAAAGCGGCCATCGTCGATCCAGAGCTGACCCTGAGCGTGCCGAAGGATCAGACCGCCTACGGCGTCTGCGACCTCATCACCCACGTCACCGAGGCCTACTTCAACGGCGTTGACGGCACGCCCATGCAGGATCGCTTCGCCGAAGGGGTCATCCTCACCGCAATGGAGTACGGGCCGAAAGCGGTCGCCGACGGCAGCGACCTCGAAGCGCGCGCGCAGGTGCAGTGGGCCTCGGTGGTCGCGCTCAACGGCTGGGTGCAGGCCGGTTGCCTCTCGCCCTACCCGGTGCACATGATCGAGCACACCCTCTCCGCGCTGCACGACATCGCCCACGGCGCAGGCCTCGCGGTCGTCAACCCGGCCTGGATGCGCTTCGCCGCAAAGACGCGCCCGGCCCGCTTCGCGCAATTCGCGCACCGCATCTTCGGCATTGAACTGAAAAGCCCGGACGACATGGAGGCCGCAATGGAAGGCATCGACCGCTTCGAAGCATTCCTGCGCTCCATCGGCTGCCCGACGCGCCTCTCGGAATGCGGCATCGGCGACGAACTCCTCGCCCGCTACGCCGAAGACACCCTGCTCGTCGCAGGCAACGCCGAAGGCCAACTCCCGGGCAGGCCGATGATGACGAAAGCCGACATCGTCGAAGTGTTGCGCTCGGCGGTGTGATAGATGTTACGATAGGGGGCTGATGATAAACACAAGCCCCCTAAAACCCGTCCAGAACAACCGACCGGAGAACCTCAACCTTCAACCTCGACCTCTTCAGAAGCCTCACGCTTTCGTCGGACATCGAAGGCGCGATCTCGGAGAAGGTGCTGGAAAAAAGCGGGGGGAAGAAGGGGGGAAGAAGAAGTGGTGATGGCGTCAGGCTGGGTTTATTCCAAAACATCTATCCGCGACGCCGTCAATTGAATAGATCATGAAAGCTGACGAGAATATCTACATCGTTTTCGCCGATATTTTTACCTGATGTAAAAGAGCTGTCAGCCCCCCTGAGGTTGTCGATGTTTTTGATAAATAAAATCCGGGATACTACAGCTACTCTTATCGTCTAACGTCTGAATTCACCGGCCTTGCGCGGCTTTATGCGCAAGGTCCGGTGGAATGATGGGTTGGGCATCATCCGTAGAACGCCTCTATGAAAGGATTCGACGGTAGGCCGATGACCAAAGGCGTAACGCTCATGGATTGCCCATCAACTGCGTTTACGATCCCAAGCCCGGCAAATTGATTCTGCCCACTTGAAGGCCGGAATTGGACGAACGCCGTTGTCGTAGTGATCCATCTCGGGTCGATCACCATTGAAACTTTAACCCCAGTAAGTTTGACGTAGATGTGTGGGTCCGTCCGCAGATCGCCACGCACAGCGGTTCTATATCCTTCCGTGGTCTGGGGCATGTCGATATTCTTCGTGCGGAATCTGGCGTCAAACGATACGATCCATCCACGAGCTTCCGACCCGCGAGACAGGGCGTTAGCCAGCGGAATGGATTTAAGCTCGATATGCTCCAAGAGGCGTTTGTAACCCGCCATCAGCCCTCCGAGTTCCCACCCCAGTTCGTGCAGTGCTACAAACTCGCCATATTGCGATAGGTTCAGAGAAGCGCCAGACATCGCCGATAGAACCTGAAGCCGCGGGACATTGAGATAGTAAAAGTTATGGAGTTTTGTTTGCCAAGGGGTCTCAAGACGTAGGCGATCAGCGACCCAAGCACCATGGTCGGCTCTGATGGATTGAAGACGATCAACTGGGTACTGCGGTACGTTGGTGTCGATCTCGTTGTGGTGGTCGAAGCAAAGAAGTAGAAGATTGCTCTCCTGATTTCTCTCCTCACCCGTAAGCGGAGAATTGCCGCGCGGACCATCCAATTGCTCGGCAACGATGTGGGCAACCTCACCTCGAAATTGAGCTGGCGTTGCGTCAAGTGCGTCGAGGTATACGCGCTCGCGGCAGATTGCACAGCAACCTGCATCACGGACCCAGACGGAACGCCTGACTGCTGGAGAGACTGGCACAGATGGCTCCTTATGATGCCCAACATTGTTTATACTGATCCGCCTAAACCGCGGATTTTTGAATCATAGTCCATATAAGACGCAATCGAGAAACCATCGCAAATACTGCTAATAACCTGATTTTTAATCACTTAAGCCTTACATTGCGTTTTATTTTTGCTTTTTATACGGATCGGCATAAGAACACGGCTCACAGCCCATCGACTGACCCACACCAAAACCGAAGCCGAGAACACACCCGCAAATCAATCACCTGAAAAATTAGCGCAAAATCCACATCCAAACAACCATAATCATCTGAGCAGCAATCCTCCAGCCGTCCGACACTCTCGCTCGACACAACCCCCGTCTGCTTCCCGCGCACTTTTCAATTTGCATCTCACCAAATCAATCGTATATTTACGATGAACTAAACACGAAATCATGCAGAGAACCCTGTCAGAAATCAGCTACACCACGGATGAAACCGCCATGGCGGCGATGGCCAAGGCACTGGGGCATCCGGTGCGGCTCAGGATTCTGCGGCTGCTGGCCGGGGAGACCTGCTGCTTCACGGGGGAGCTGACCGGGCTGATTCCGATGGCGCAGTCCACCATTTCGCAGCACCTGAAGGCGCTCAAGGAGGCGGGGCTGATCCAGGGCGAGATCGATCCGCCAAAGGTGAAGTACTGCATCGACCGTGAGAACTGGAAAAGGGCGCAGACGCTCTTCGGGGAGTTTTTCGCCTCCGAAAAGAGCGGCGGATGCGGGTGTTGAGATCGGAAATCGTCGAAACAAAGCTTCTTCAATAAATCGTTCATTTACGATAAACTCACAACAACAGAACAATGAAAGAGATCAAGATTCTCGGTACAGGATGCGCCAAATGCAACCAGCTTGCCGATGCGGTGAAAGCGGTCGTCGCCGCTGAAAACATCGAGGCCGATGTGCAGAAGGTCGAAGACATGCAGCAGATCGTGTCGTATGGCGTGATGTCAACGCCCGGCCTGGTGGTGGATGGCAAGGTGGCGTGCACCGGGCGCGTGCCGTCCGGCGACGAACTTCGCCAGATGCTCACCGCCGCGCCGAAGCCCTCCGGCTGCTGCGGCAACCACGCCAAAGGCATCGGCCGCCAGAACGGAACCTGCTGCTGAAGCAATGCAGAAGCACGATTCGCGCAACTCCGGCGGCTTGCTCGTTTCGACCCCGGCCTGGATCGCCGGGGTTGCGGCTGCGGTGGCGCTCTGGGCGGCGCTTTACCTGAACCTCGAAGCTGGCGCTGACTTGCTGGTCGGCGCTCTCGGCCTGAGCCGCACGACCCCGTTCGGCGAGGCGCTGCACTTCTTCATCTACGAAACGCCAAAGGTGCTCCTGCTCCTGACGGCGGTGGTGTTCGTGATGGGGGTGGTGCATACCTTCATTTCGGCGGAGCGGACGCGGGCGATGCTCTCCGGCAGGCGCGTCGGCGTCGGCAACGCGATGGCCGCCACGCTCGGCATCGTCACGCCATTCTGCTCCTGCTCCGCCGTACCGCTCTTTATCGGCTTTTTGCAGGCAGGGGTGCCGCTCGGCGTCACCTTCTCGTTCCTCATCTCCGCGCCGATGGTCAACGAGGTGGCGCTCGCGCTGCTCTTCGGCATGTTCGGCTGGAAGGTCGCCATGCTCTATCTCTCGATGGGATTGCTGGTTGCGGTGATCTCCGGGATGGTGATCGGCAAGCTGCGGCTGGAGCGCTTTCTGGAGGAGTGGGTGCAAAAGATCCAGAACAGCGCGGTCTCGCAGGAATTCTCCGCCGATGCCGTGAGCTGGCCGGAGCGGATTCGTGAAGGCATGAAGCATGTCCGGGAGATCGTCGGCAAGGTGTGGCTCTACATCGTGCTCGGCGTAGGCCTCGGCGCGGGCATCCACGGCTACGTGCCGGAGAACTTCATGGCTTCGCTGATGGGCAACGAGGCGTGGTGGTCGGTGCCCGCCGCCGTGCTGATCGGCGTGCCGATGTACTCCAACGCCGCCGGAATCATTCCCGTCGTGCAGGCGCTGCTCGGCAAGGGCGCGGCGCTCGGCACGGTGCTCGCCTTCATGATGAGCGTCATCGCCCTCTCCGCGCCGGAGATGATTATCCTCCGCAAGGTGCTCCGCCCGCAACTCATCGCGGTTTTCGCCGGAGTCGTGGCGACGGGCATCATGCTGGTCGGCTTTGTTTTCAACGTTTTGTTCTGAATGGATGGTATCGCTCCAGCAGTGAAAAACCGGAAAGGAATATCAAAAAGAGGTCTCTCATTCTGTCCTGACAAGTCGGCAGAAAATCCGTTTTTTTCGAGCCGCACGATATTTGACTGATTCGAAACACTTTACGTGGCTATTCTGGACTCTTCGCCCGACTTTGTCGGACTCAGAATGACAGAAAAAGAGCATATACAACAATTGATCGCCATCAACCACAAACACAACTCAAGTCATGAAACAGTCGATACTTGTCCTCTGCACCGGCAACTCCTGCCGGAGCCAGATGGCCGAAGGGTTCCTGCGCTCCTTCGACCCCGAACTCGAAGTATTCTCCGCAGGCACCATCCCTGCTGGCGAAGTTCATCCGCTGGCGGTTCAGGTGATGAGGGAGGCCGGTATCGATATTTCGGCAAACCGGCCAAAAAGCGTTGACGAATTTCTCTCCAGGCCGTTCGATTATGTCGTGACAGTCTGCGACGGCGCGAACGAGTCCTGCCCGATGTTCAGCGGCGAGGTGAAACAGCGCCTGCACATCGGCTTCGACGATCCGGCAGGGGCCACCGGCAGCAGCGACGAGGTGCTCGAAGTCTTCCGCCGGGTGCGCGACGAGATCGAAGCTCGGTTCGGCGAATTTTATCGCGAAACCATTGCAGGAGTCTGATCATGAGTAACACGACAAAACAGCTCTCGTTCCTCGACCGCTACCTGACGCTCTGGATTTTCCTGGCGATGGGCGTCGGGGTGCTCTCCGGCTTTCTCTATCCGCAGATCGCCGGATTCTGGAACCGCTTCAACTCCGGCACGACGAACATTCCCATCGCCATCGGCCTCATCGTGATGATGTATCCGCCGCTCGCCAAGGTGAAGTACGAGGAGCTTGGCGACGTATTCCACAACACGAAGGTGCTGGGCCTGTCGCTCGTGCAGAACTGGGTGATAGGGCCGGTGCTCATGTTCGCGCTTGCCGTGCTGTTCCTTGCCGACATGCCACACTACATGGCGGGGCTGATCATGATCGGCCTGGCCCGCTGCATCGCGATGGTGATCGTCTGGAACGAGCTGGCCAAGGGCGACACCGAGTACGCCGCTGGCCTCGTGGCCTTCAACTCGGTGTTTCAGGTGCTCTTCTTTTCGGTCTATGCCTGGGTGTTTCTGACGGTACTGCCCGGCTGGCTCGGCTTGAGTTCGTTCCGCGTCGAGATCACCATCGCCGAAATCGCCTCGTCGGTCTTCATCTACCTCGGCATTCCCTTCATCGCCGGATTCCTGACGCGCTTCGTCATGCTGCGGCTGAAGGGGCGCGAGTGGTACGAAACGGTTTTCGTGCCGCGCATCAGCCCGCTGACGCTGGTGGCGCTGCTCTTCACGATTGTGGTGATGTTCTCGCTCAAAGGTGAATACATTGTGAAAATTCCGATGGATGTGGTGCGTATCGCCATTCCGCTGCTACTTTATTTTGTCATCATGTTCCTCGTGTCGTTCTGGATGGGGCGCAAGATCGGCGCGGACTACTCTAAAACCGCCACGCTCTCCTTCACGGCGGCGAGCAACAACTTCGAGCTTGCCATCGCCGTGGCGGTCGCGGTCTTCGGCATCGACTCCGGCGAGGCCTTCGCCGCCGTCATCGGCCCGCTGGTGGAAGTGCCCGCGCTCATCGCGCTGGTGAACGTCGCGCTGTGGTTCAGGGAGAAGTGGTTCGGCGGCGTGAGCGAAGCCTGACAAGGCCTGAATGTTTGCTTCGAGTTCAAACAAAAACCTGTACGAAGATGGAAAAAAAACAACATGTGCTCTTTCTCTGCACCGGGAACTCGGCGCGGAGCCAGATGGCCGAAGGGCTGCTCAGGGAGATGGCTGGCGACCGGTTCGTCGCCATGAGCGCCGGGCTGGAACCAAGAGAGGAGGTGCATCCGCTCGCGGTTGAAGTGATGCGGGAGGTCGGCATCGACATCGCCTCGCAGAAACCCAAGCCGGTGGACCTCTACCTCGGCAGGGTTCCCGTGCACTATCTCATCGTTGTCTGCGACAAGGCCCAGGCAAGCTGCCCGAGAATCTGGCCGGGCCTTCTCGATGGACGCCGTTTTTTCTGGCCTTTGCCGGATCCGGCCGATCAGAGCGGCACCAGAGAGGAGCAGCTTGCCGGCTTCAGGGCGGTGCGCGATGAACTGCGCGGACAATTGCAGGAGTGGGTTAAAAGTGTCGAGTGATCTATCCCGTCCGCCGGAACTACTAAGTCCTTCTCCATAGCGATTCAACCTGCCCGTCTGCCGACCGCGAGGCTGTAAAATCCGGCAACGTGATTGGTTGTATCTTCGCATGAAACATCGGTTTGAGCGCTGTTGGCTTTCTGATTGACCAGCGCGAATCGTTGCAGAAACTGGTTCAGCGCCAGGCTGCCGCAATCGAACACTGATACGTCGTGTGTGGAGGCGAGCTTCTGAACCTGGCTGAAACGGGCATCCGTCAATCGAGTACTCCCGGCTCGGTCAGCAAAGCTTTCATCCGACTGTCGGGAGCGGACACCGGCCAGTCGAGCAGCTTCAACCTTCCGCTCGTGGACTTGTAAGGAAACTCTTTGGTGTACTCGAAGATATTCAGGATCATCACGTACACATCGCAGTAAACCGGAAGTTCATCATACAATGCCATAACTCGTCAGCCTCAGCAGGGGGCTCCCCCCCCCCTGCTCCTCCCCTCAATAAATTGATGTATAGATGAATGGTTAAAAAGCCCGCACCGGACGAACACGGAAATTGTCGCTGCCCTTGCTGAAGTAGGTCTGGCCGCCATCGACGAAGTACTGGAGCCACGCGTAGTGGGCACTGACCTCCGTTGAACTCCAGTAGCTGTCGTCGGCAAACCCTCCAACGACCCATTTGTGCTTATACAGCTCACTCAACTCCCATTTGCTCGGTAAATACCAGTCTGAGTAACCATTATGAACAAACCGCCCACAAGCCTCTTTCGCCTGTTGCCAATCATAGTTGTTGCCCGGCAAATCTCTGGTCGCGGCAACGAGACCGTGCCGACCTGACTCATCGACGTTGAACACAACGCCCCCGGCATAACGCTGCCCGATTTCGACGGCTTCCGCCTGAGACGGACGGGCTACTGCCGATAATAAAGCGAACACGATGAACACGTGTCGCCAATCGATTACTGATTTAAAAGTATAACGCATTGTTGATCTCGTTTTTCAGGTTTTTGGATGAGACCCAAGTGGCTACCGACAATAGCCACCTGCATCTCAAAAAATTATACTATTTCAGGTTCATCGTAAAATTTAATGGTAACGCTCGTCAGCAATTACGTCAACCGGTAATAGCCATGTTGAGCTTTCCACAGTAAAACAAAATCCTTATGCGGTAGCTGTGAAAGCTGTGGAACCCACGAGCCGATGCTTTGTACAACTGGATCTTGCTGTTCAGACCTTCGGAAACTGCGTTGGTCATTTCGTGCTCGAAATAGTTCAGGATGTTGTCGAGATGCCGCTTCAGCAGCTCTTTGACCTTGATCATGGGTTTCAACGCTAACTGGTCAACGCGTTCAGACCAGTAATCGAAAAAGAAGCTTGCACTCTCTCGACAACCCAGCCGCCAGAACTCCCGAAACATGTTCTTCATCGACCAGGCTTTTCCGGTTTTCAGCTCACAGGCCATCAATTGATCAAAGCTTGTCCGCTGGCTTTCCGTCATGTTCTCCGGATTGCGCAGCCAGGTGAATTTCGAGCCAATCAGAGTCCTGTCCCCTGCATGATGAAGTTGACGGGACTCTTGGCGACGAACCGTGTCGACCGCCTCGTTCAGATATTTGCTGATATGGAAACGGTCATGCACAATATCGGCCTGCGGCAGATGCTTTTTGGCAGCAATCGCGAAGGGTTTCCACATATCCATCGAGATCGATTTCACACCCTGGCGTTGCGATGCTTCAAAGCTGAGGAGTAGCGCTTCTGCTCCATCGGTCGTTCGGCTCTGGACCACCTCAAGTACCCGGCCACCTTTCAGGTCGTTCAGGATCGTCACATACTGATGGCCTGCCCGGAAGCTCTTTTCATCAAGACCAAGATGAGCAATCGCCTCCTTATTCCGGCGGCTCAGGCCTCGCTTAACCGCACGGTTCATGATCTCGTTGGTTGCATGCCAGTTCAATCGCAAGAGCCTCGATGCCGACTGAATGCTTGAACACTCCTGAAGCAACTCGACAGCAAGCGCTTCAAACTTCAGGGTGTAGCGCGAATAGCGCGTTGCCCACGGAACTTTAATTGTCTTGATCCTGTGCTCTTTGCACTCACACCGAGGCACCCTGGCTATCAGATGCGTCTCATACTCCATGGTATCCAGATGCCGCCACCGTTGTTCTGGCGCCAGGTCATAAATTCGTCCGGCCTTGCCGCATTCAGGGCATTCGACTTTGGGTCCGATATACTCCAGATGGATTTCTATCCGGGGGCCGGACATCGACAGCCGGACATCCGACACCTTCCATGTTTCTGGTAATCCTAATAACTGCTGGTAATGGGCAATGAGGCTCGGCATACGTTGGGGTTAGTGTTTTGGCGTTCTTGGATAAATTACACCAAGCCACTCATTTTTACTACCAGCCCATTAAATTCTGCGAAGAGCCCTATTTCACAACGAACTCGACACTGGCTCCGTTTTTGCAAGAACCACGATCATCACCATCTATGTATATATTTGCAAGCGATCTATCACCGCTCCATCTCAAAGTAGCCTCTCCGTTCCCATTAGTATAAACGTTCTCTACCATTCCGCCCCATGAGATGTATCCTCCTATCTTAACACCGCTACGCGGCTCTCCACTTGGCCAGGTTGTCTTGACGTAACACTCACCTGCCTGTACAGCAGCAGGAAGGGCCATAGCGCTTAACAGAAAAAGTAATGTTGTTTTTTTCATCAGTATTCATTTTATGGTTAGATAAAATCTCATGCCCGGCAAGTACAAGAATGCTTTTAACTTGCAATTAAGCATAAAATTGCAAACAAATTTTTCATGCATTCTCCTTTTTTTGTTTCAAGGACGTTCACTTCATGATATCGGAATACTTGATCCATATTTCTTTACCCAGCGCATTCGACTTATAGGCGCTTACCGCCCGCTTCTCGTATTCGAGGTATTTTATCGAGACCGCGAACGGCACATCCAGCGTAGCCGAACTTACCTGAACCAGTAGCGTTTCATTTTTGATATCGACCTGTTTCACTTTGCCTGTCAGAATGAACTTGTAGGTCACCCACATGTTTTTTCTGAAAAACATGATCTGCATCACCTCATCCGTCTCGTACTGATAGGAGACTTTCCACTTCACATTATTGGCTACAAGGGCCTTCAATTCTGCGATTCTCTGTTCCTGAGCAATTTTATCCCTGACCGACTGGGAGTAGTATCCATCCGGATATTTCGTCAGGTATTTTTGCAACCCCATACGACCTCCTTTCTGCGCCAGCCCGTAGGCTGCGATCTCGTCGGCAACCTTCTTCGCCTCGGACGAAAACTTGCTGCCTTGCGACAGATAGCGAGCCAGAGGCTTGGAACTCGCCGCCGAATAGGCATCTTTTTTTGCCGTTTCAAACATCTCCGTTTCCCTGGCCTCAGCTTGGCTCACTGGAGAAAACTGAGCCATACTGCCGATCCCGTAAACTTCGATCTCCTGCCAGGCAATCCAAGATGGCGATGAAACCGATTTTACCATCATTTTCGATACGTTGTGCAGAGGAGGCAAAAACTCCTGCACCAGCGGCACCCCATCCGAAGTGTATTCTTCGATCCGAGCCACCATGCGATACGTACCCGTCGAATCGGCGGCATAGACTTCATGTGCCGTCCGGCCTGCAGGAGATTGACCGGGAACTAATCGCATCTTCGTGATGATGTTCTTCTTTTTTTCGAGCTCGAACTCAACGCTTTGCGGCGCGTAATCCCCAGCATTCCAAGCACTGACGAGGCTACCATCCCCAATATTTTCAGCCCTCGTACCAGCATAGGTATTTGACGCGACCATATTAGTTAACCCGATCCGCTCATCACTCTTTGCTGACTCATCGACAGCCAGTCCGACACGAACACCAACCCCACTACTCAACCATACCGCAAGCATGATCCCCTTCAGATTTCTTATCATAGGGTTTGCTGAAGAATTCAAGCCATCGCCCCGCGGCACTCAATCGCCGCTCGGGGAGGTGACCACGCGAACAAATTTCTGATTACATCAAGCTCCAAAAGGAGCCATTCAAACAGGCGCAAAAAAGGAGCGGCGAGCAGCCGGTCCAAGTTCATCACGAGGAACGTGATCGAGACCACACTCAGACTGCTCTCGGCAAGCCTCGCCATTACCCGGCCCAGCCCGTATCGGCGCTTCGCCTTACCGAACATGCCTTCGACGGCATTCCGGACTCCTTCGTCTTCCCTGATCTGCCGCCGGCGGGCCCGGTTCTTCTCAACATCCTTCGGGGGCCGACCGAGCGGCACGCCGCTCAGCCGGATTCCTCGTGCCTTGCACCACATCCGGTTGGCCAGCGTCCGGTAGATCTTGTCGGCATGGACTGATTCGGGATAGTGCCCGTAGCGCTCGCGATATCGCTCGATATCCCGCACCAGGTCGCAGCCTTCGTTGTAGGCGTTCCAGCTCATCCGTTCCGGCAGGCTGATGCCGTCGACGACGCTGATGGAGAGCTTCATGCCGAACTCCGTCCTGGCTGCGGCCTTGCCCCGTACGATCGGCCTGACATGGGGCTGGCTGATGCTGACGATTCGATCGCTGATGCTCTTCCTGTCACTCTTGTACATTTCCTGTTGCTGCCGATACAGCTCATCGATCACCAGCAGGTCGCGATACCGCGCTGTCGAGAGGACGGTCAGCGGTACAGCGGCGCTGAGCGCTTCGATATGCTTCAGGTTTCGACCGATGTACTGCAACTGCTGGCGAATGGCTCGACGAAGCGCTTTTTTCGACAGGTTCCGCTTCATGATTGCCGAGAGAAACGCTTTCCTGGCCTTCTTGCGATACGTCCTCGGCTTGCCCAACTCCTGCGGAGCATTGGCACACAACTGGTCGATGATTTTCTCGGTCTTTTCCCGTGCTTCGTTGAGCAGACCAATATCCGTCGGATAGGCGATGTCTGCCGGTGCGCAGGTGGCATCAACGATGAGTTTGCCCTTGTTGCCGGAACCACCGTCTCCGTCGTCATTCTGGTTCCTTTCCTCAGCCTTCCTGCGCTCTTCAGCCAGATGGCGTTGCAGGAGTTCCTCCTGCAACGCGGCCAGATCGGTATGCTTCAGCCGCTTCCGAAAGTGGGTCAGCATCGAGGCATCGAAGGGCGCTGCATGCTGGTACGTTTCAAGACCGATAAAGAACTGGAGATACGGGTTCTCCTTGATCTGTTCGACCGTCTCGATATCCGAAAGGCCGAGCTTCTCCTTGATAATCAAGGACCCCAGCGCCATGCGAACCGTCAGTGCAGGAGCGCCCCGTTTCGACATGAAGTTTTTGGCATACATCGTCTCGGCGACGTGCCAGGGAATTACGTCGGCGAGCTTCACCCACCGGTTTTCCGGATCGAGTTTACCACCAAACGGCAGATGGAAATTTTCGAACGTGAGCTGCTGAAACTTCGGCTGGTACAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP017305|1893226:1954285|1945576_1946638_+|WP_069810400.1|DBSCAN-SWA
MQKHDSRNSGGLLVSTPAWIAGVAAAVALWAALYLNLEAGADLLVGALGLSRTTPFGEALHFFIYETPKVLLLLTAVVFVMGVVHTFISAERTRAMLSGRRVGVGNAMAATLGIVTPFCSCSAVPLFIGFLQAGVPLGVTFSFLISAPMVNEVALALLFGMFGWKVAMLYLSMGLLVAVISGMVIGKLRLERFLEEWVQKIQNSAVSQEFSADAVSWPERIREGMKHVREIVGKVWLYIVLGVGLGAGIHGYVPENFMASLMGNEAWWSVPAAVLIGVPMYSNAAGIIPVVQALLGKGAALGTVLAFMMSVIALSAPEMIILRKVLRPQLIAVFAGVVATGIMLVGFVFNVLF
>NZ_CP017305|1893226:1954285|1910639_1912067_+|WP_084022369.1|DBSCAN-SWA
MTTRSTNPEKRTPSMTDNRSAQEARALEKRLSGRSKGRRGWRRHAAFAVSTALSELIVRLIEIGVALSVTLFAFVPVLLARLAHRLPAGKPVFSKRAVFGRSGKPLTLLSFDGLSGGMATLPWFLELFTGRIALAGTAIRDWHPAAAPEQGYISMVKPGIVSLWNVRQSSRIAHEGREATEWEYIFSKRPAYDFLLILRALPALLFSEKEASPSPLFNLLDLKIDNISMREAISMIRQSIEEQRQSAIFFVNPDCMNKSVTDRGYRKALASADHILPDGIGLVIAGKMLGTPLCENINGTDMLPFLCEMAASQKRSIYLLGGKPGVAEKAGDAIAQNHGVTIAGAMHGYFDHETESAGVIEAINRSNASILLVAFGAPLQEQWIVRHRAALRPAILMGVGGLFDFFSGNIQRAPRWMREIGLEWVYRILQEPGRMWKRYVVGNPLFLYRVMKWKVLGQSSNPENQWNSIQPSGGN
>NZ_CP017305|1893226:1954285|1936863_1937304_+|WP_069810390.1|DBSCAN-SWA
MDLSNLLQLGASTILHNSDQATNGLDSNELVSALSGLLGGGGGNMNLGAILSKMQQSGLGDIAASWLGNGANAPISPGAVTDLIGSDKIADFASRFGLSEESAKNAIASALPEMVDKASPNGSLLEGLIGNISGLGGLSDMVNKFF
>NZ_CP017305|1893226:1954285|1948892_1949108_-|WP_069810404.1|DBSCAN-SWA
MTDARFSQVQKLASTHDVSVFDCGSLALNQFLQRFALVNQKANSAQTDVSCEDTTNHVAGFYSLAVGRRAG
>NZ_CP017305|1893226:1954285|1913126_1914521_+|WP_069810369.1|DBSCAN-SWA
MKTILAFREEAFAWSHEVFPCVHPLLLPLCNKPFIEYLIDLAILTGSTAVRILCDGGLGPVERYCEDGSRWGIALSYESLHADDTVPILLGKNRRFCGSERIMVVSGFSFIRYDKRLDYKSLAGSRPEGEWVSSPGGSITLSGPPEQPRTDGTNPPLSLMPLDGLATYYRASMEALETGADRYVLPGYGGEPGCSIGRNVVISKSVQIRKPVSIGNNVQLLGDTIIGPSAIIGSNVIIDRESSVESSIVLDNTYIGEHLEVNGRIASGNRLNDPVSGASISMEDPHLLGSIKKSRALSALPRKIAHALAALVMIAVLSIPFLLLAPLLRFGGRWKSARIECLSENPDDTIPLGKVELDTVNAPGAIAAALSLDRYIWLFRVLTGQLALIGSTPLPADANQPNSPANALAYRPGVFSYAEAEEWPATGGDAAIVERFHLTHGSTLADIGLSIKAFINRLQEKSTV
>NZ_CP017305|1893226:1954285|1912033_1912753_+|WP_069810367.1|DBSCAN-SWA
MELDPTVRRELIRKIGGNIRPSLRLRGKMKVAAWENTIRLSYLAKRLLDIVVSTLALVALLPVFIVTALSIVVENPGPVFFVQIRVGRNGRHFRFYKFRSMVVNAEKLKTELAAHNESKDGVIFKMKKDPRITRTGRIIRKFSIDELPQLINVLKGDMSLVGPRPPVPKEVEQYTLEQRKRLHAIPGITGLWQVSGRSDIPFTDQVRLDLQYIQSAGVINDLRLLLRTIPAVLSGKGAY
>NZ_CP017305|1893226:1954285|1942345_1943089_+|WP_084022372.1|DBSCAN-SWA
MLQQTLITDEKTTIKSFVGAKCLYPKAAIVDPELTLSVPKDQTAYGVCDLITHVTEAYFNGVDGTPMQDRFAEGVILTAMEYGPKAVADGSDLEARAQVQWASVVALNGWVQAGCLSPYPVHMIEHTLSALHDIAHGAGLAVVNPAWMRFAAKTRPARFAQFAHRIFGIELKSPDDMEAAMEGIDRFEAFLRSIGCPTRLSECGIGDELLARYAEDTLLVAGNAEGQLPGRPMMTKADIVEVLRSAV
>NZ_CP017305|1893226:1954285|1914517_1914853_+|WP_069810370.1|DBSCAN-SWA
MIITETSNDGIAIVALEGTLDALSAPELRNIRSVTDPEKTVILDLEKVDFIDSSGLGAIVGATRVKLDPARGVVLACLNDRVRKVFEITNAQKLFHIFDDTSAAVDFAATR
>NZ_CP017305|1893226:1954285|1926234_1927674_+|WP_069810380.1|DBSCAN-SWA
MHEGEGNIMVAVALFGWIPIVRAIFKRFDARTAVAIAFVVGWMFLPVAGFKVKGIPSYSKLTATCMVILFWARHFDKERFREFSFGLIDLPMLAWCVSPFFSSVFNDLGAYDGLSQTMYQSITWGVPWYIGRVYFSNADGLKLFGTAIFIGAVAYIPFCWFELVMSPQLHRLTYGFHQHSFLQTLRDGGGFRPMVYMDHGLMTSTWMGLGLFLGAWLFYTRDLPEKILGLPSLYLLLALGVTFLMMKSYGAIFLIFLGLGFVFLSSRMKKNWLVVLLLAAPHLYVYTRTTGIWDGTNLSGFVAEKFSPTRAQSLQFRFDNEAILIQKALDGTVFGWGGYGRSRVYDEYGKDISITDGLWIITLGQNGIFGLMALMFAVHTPVIFYLMRSDPERWSEKNRGAPTVMIVFLSLYMIDSLLNAMVNPVYMVFGGGIVSMLLKGEAAFNTEPADGSIEEARIDMPNTRFLPSPSFQGSSRFIS
>NZ_CP017305|1893226:1954285|1947307_1948363_+|WP_069810402.1|DBSCAN-SWA
MSNTTKQLSFLDRYLTLWIFLAMGVGVLSGFLYPQIAGFWNRFNSGTTNIPIAIGLIVMMYPPLAKVKYEELGDVFHNTKVLGLSLVQNWVIGPVLMFALAVLFLADMPHYMAGLIMIGLARCIAMVIVWNELAKGDTEYAAGLVAFNSVFQVLFFSVYAWVFLTVLPGWLGLSSFRVEITIAEIASSVFIYLGIPFIAGFLTRFVMLRLKGREWYETVFVPRISPLTLVALLFTIVVMFSLKGEYIVKIPMDVVRIAIPLLLYFVIMFLVSFWMGRKIGADYSKTATLSFTAASNNFELAIAVAVAVFGIDSGEAFAAVIGPLVEVPALIALVNVALWFREKWFGGVSEA
>NZ_CP017305|1893226:1954285|1943542_1944439_-|WP_157098406.1|DBSCAN-SWA
MPVSPAVRRSVWVRDAGCCAICRERVYLDALDATPAQFRGEVAHIVAEQLDGPRGNSPLTGEERNQESNLLLLCFDHHNEIDTNVPQYPVDRLQSIRADHGAWVADRLRLETPWQTKLHNFYYLNVPRLQVLSAMSGASLNLSQYGEFVALHELGWELGGLMAGYKRLLEHIELKSIPLANALSRGSEARGWIVSFDARFRTKNIDMPQTTEGYRTAVRGDLRTDPHIYVKLTGVKVSMVIDPRWITTTTAFVQFRPSSGQNQFAGLGIVNAVDGQSMSVTPLVIGLPSNPFIEAFYG
>NZ_CP017305|1893226:1954285|1944862_1945195_+|WP_069810398.1|DBSCAN-SWA
MQRTLSEISYTTDETAMAAMAKALGHPVRLRILRLLAGETCCFTGELTGLIPMAQSTISQHLKALKEAGLIQGEIDPPKVKYCIDRENWKRAQTLFGEFFASEKSGGCGC
>NZ_CP017305|1893226:1954285|1922024_1924322_+|WP_069810377.1|DBSCAN-SWA
MMKDNAPKEALPFGKPNKPIDIVGFVKRYGLFVLVIGAFLFTLTVPLVLLISKPNYEVHALMRIDPVIPSVITKSEDPSIMNYYSDYSNTQARRMMDFDVLEATVKKLTPDQRNAIFPPNLPTATCAEIAGIIIKINPVPGTHLIDISVSGPKKKGLAPLVNSLMRVYLDKMRRGNEMQDNERLVYLKNEQQALTNDIAAIEEKLNLLTKEISTADFGEDNNIASKRADELQQASVNAFTERISSENQLREAEKNSQQLKKLSLDPMVEERVMGDQSLHSTSSWTYQQQQQLRSTTDGLTQNNPDRIYVEQRMKAMRDYEKKLQNEVRNSAKMIVYGKRDYEQKRELILSKNKAEKAKSTEEELLKELDKTRQESVRISLGLHLGEALKSSLKHKRDLLDQIDTRIHELELEGKAPLHVAIESLAREPESPAGSNTKKLMLVFFAISFGSVGVLFAAVDFLDNRIRRKEDIKAALGYPPAKEIPESAEKKPLLDVLELAPGDPAAQAIRSLAVKLVHENRQSGSKIILFSGVERQTGATSLAWNCARALGSLAPKVLLIEAATNAPPLSKLNGLAKEPAGVRELLAGTKSPEEVIVSGGEGSPDMLYHGEAAAGITPQQRLPGILAALRERYDFICIDAPPVLESNLTENLALHADIVTLVALGESTMYRDLRAAAEVFVRLEVPAIMPILNWGGPAKSSTIDRLLEKPPEFLDRIETGKLEALLRNLPSGDRLFDLAASVLASLKKAAKPKKSGPSGNRQRTNP
>NZ_CP017305|1893226:1954285|1917923_1919111_+|WP_069810374.1|DBSCAN-SWA
MQKPSLTIIPSVPVWKQGETLRFDRKFYDGLLRYTELWPGPITCVMAQSSSPLPDFGVVEATPGVMPFTCIALKESEIVGKEHIRDATIVLASADAHDQLHLAALCRQMGVRCVYVIEYIPETRYQIAALDNRNPAAALRQKLYLWLGERKRRKAFELCDGLQCNGTPAYHEYRETPNRLLYFDTRVSKEQLIGDAELEARLATLREKKPLRLAFSGRLVAMKGADHLVRLALKLKKLNLPFHLSIYGAGELEAEMKRSIERNELNELVTMEGAVDFQRQLLPDLKKKVDLFVALHRQSDPSCTYLETLSCGVPIVGYRNQAFGGILDLAEIGWGVKPDDIDAVSWMILRLDLARDEIAEKSGNAAGFGRQHDFDTTYRNRIDHLLSITNGRKRS
>NZ_CP017305|1893226:1954285|1916268_1916778_+|WP_069810373.1|DBSCAN-SWA
MALFSNIRADLKTYGGQWSQQGFWVMIVYRYGRWRYGIKNSVLRKPFSLLYRFFYKVVQILTGIELPCEVPVGRNFRIDHFGDIVISGYASFGDDCIIRNGVTVGLKNIEEKAAPKIGNNVNIGAGAKLLGNITIGDNVDVGANAVIISSVPANSIAVGIPARIIPKKS
>NZ_CP017305|1893226:1954285|1907195_1908938_+|WP_084022368.1|DBSCAN-SWA
MFAMPKIDTFIGRSNTIRNALTEFELRNKLMLFSAAITQLPMAVVITSDQGIIEYSNPGFTALSGYTEAEAKGQPMSILNSGVQSKVFYRNFWETINAGKIWQGEIVNRKKSGEHYTEYCIVCPITGPDAEIVHFISIKQDITQRKKEQEALAESEQSFQELANLLLQPVFEVDLKGNIVFSNKAGLDLFGYTRYDIEEQEFEAIRLFAPEERPRVLQNMAARIQGITFENHEYTALKKDGTPFPILIYSEPIIRRGIPVGVRGLCLDISERKRNEEKLLELNQTLEERVEERTRELEVTHQQMILQEKLASIGQLAAGLAHEINNPVNFVRINFATLREDVSDLGQLIREYRAVFQEIEHSGLAPEAMERLKALEKKLKVDEVLDELPELFDESRRGFERIGTILSSMRNFSFRHALNQRVPFDLNQGIRDTLIIAQNEYRYYAEVETRLGELPAAPCNPEQINQVFLNIVVNCAHAIASQKRHEKGRIVIETGNGDDNVWCTITDDGPGIPEQIRNRIFEPFFTTKDPGKGTGLGLSISYDIIANKHGGSLTVSCPPEGGSVFTIRLPLKAAEASTSS
>NZ_CP017305|1893226:1954285|1949363_1949822_-|WP_069810406.1|DBSCAN-SWA
MRYTFKSVIDWRHVFIVFALLSAVARPSQAEAVEIGQRYAGGVVFNVDESGRHGLVAATRDLPGNNYDWQQAKEACGRFVHNGYSDWYLPSKWELSELYKHKWVVGGFADDSYWSSTEVSAHYAWLQYFVDGGQTYFSKGSDNFRVRPVRAF
>NZ_CP017305|1893226:1954285|1915287_1916262_+|WP_069810372.1|DBSCAN-SWA
MVTVVIVSYNTREILSNCLDALFKSGMGREMEVFVVDNDSRDRSAEMVAEHFPEARLIANKQNLGFAAANNQAFRQATGEYIVLLNPDAYVLPSSIPNAVRFMDEHPECGLCGGKIISPEGRLEPSARRFPSPLTKLLTLSGLRAKFPQSRLLNWHEFGDFAHDRPMEVDWVPGTFTIARKAMLDKIGPFDERFFIYYEETDLCLRAKKAGWKVYFIPDAEVMHIGGASSKTRKDKTFDSAASQVLSFRMRSEWLYYRKNYGLATMLASAGIELLWFSMRYLKNLLIPTGDAARKKEMARSTMSQITRSVSDTQFGQFSPPIPW
>NZ_CP017305|1893226:1954285|1932956_1934159_+|WP_069810386.1|DBSCAN-SWA
MQIIVPTVTLLVILLSLPAAYLFIVTVAAYLFRKEALAANRILEIGVLIPAHNEEAGIVGTIESIHASDYPAENVKIFVIADNCDDTTAEVARNAGATVVERFDLENRGKGQALDWFLRKHKELNHGLDVITIIDADVRVDRNYLREVSLSFSQPGIQALQGYNGVSNPEAGWRPGLLDAAFNVFNHLRMAGPFQLSGTCALKGNGMAFDRFLIEETGWPCHSIVEDMEFSFLLLMNEISVHYNPDAIVRSEMVTSGKNASSQRSRWESGRFKLVSQMALPLLRLFFSTGQIRYLIAFAELAVPPLTLLVLLFAVASLLALTLLHGAWLQIVAAWWAILLFYVVSGQIQRHAGLHTWRVLIAAPLYILWKIPLYLAMAIRKKSDAWVRTKRESEASEPEA
>NZ_CP017305|1893226:1954285|1952800_1954285_-|WP_069808503.1|transposase|DBSCAN-SWA
MYQPKFQQLTFENFHLPFGGKLDPENRWVKLADVIPWHVAETMYAKNFMSKRGAPALTVRMALGSLIIKEKLGLSDIETVEQIKENPYLQFFIGLETYQHAAPFDASMLTHFRKRLKHTDLAALQEELLQRHLAEERRKAEERNQNDDGDGGSGNKGKLIVDATCAPADIAYPTDIGLLNEAREKTEKIIDQLCANAPQELGKPRTYRKKARKAFLSAIMKRNLSKKALRRAIRQQLQYIGRNLKHIEALSAAVPLTVLSTARYRDLLVIDELYRQQQEMYKSDRKSISDRIVSISQPHVRPIVRGKAAARTEFGMKLSISVVDGISLPERMSWNAYNEGCDLVRDIERYRERYGHYPESVHADKIYRTLANRMWCKARGIRLSGVPLGRPPKDVEKNRARRRQIREDEGVRNAVEGMFGKAKRRYGLGRVMARLAESSLSVVSITFLVMNLDRLLAAPFLRLFEWLLLELDVIRNLFAWSPPRAAIECRGAMA
>NZ_CP017305|1893226:1954285|1937376_1938255_-|WP_069810391.1|DBSCAN-SWA
MKRVLVAGATGYLGRYAVQEFKNRGYWVSALVRNPEKFKKPGPFFAPQIDTLVDEVVFGDATKPETIAGLCDGIDVVFSSLGMIKPDFEHDNFDVDYQGNMNILAEALKAGVKKFVYVSVFDAHRMMNIPNVQAHEKFVRELQATKIESTIIRPNGFFSEIGQFVARARRGFMLWIGDGYNRQNPIHGADLAKVCADAVDSSEREVEVGGPEVFTYREMVDLAIEIAGTQPVQLPLPFWLADGIVGVVGIFNRDVADVALFATTLSKMDFVSPKYGTHRLRDFFNECKNLPL
>NZ_CP017305|1893226:1954285|1900395_1902960_+|WP_069810360.1|DBSCAN-SWA
MSLISQYRAHTEERAQLGIPPLPLTAAQAVELIALLKENPVQEQEYLLDLFVNHISPGVDDAALEKAAFLDAIIRGEASCAVITPVEAVGILGTMLGGYNVKPLVDALSSADSAIAEAAVLALKKTLLVYDSFDAVVELAKTNAYAKEVLESWANAEWFTSLPTLPEKMTLTVFKVPGETNTDDLSPASEAFTRSDIPMHALSMLRSKMDNPIETIASLKEKGHPLAYVGDVVGTGSSRKSGINSVQWHLGADIPAVPNKRTAGVVIGGIVAPIFFNTAEDSGALPIQADVNSMDMGDVIEVYPFRGVIEKNGEVISTFTLEPNTLADEVRAGGRITLIIGRNLTRKARKVLGLGEETIFSRPEQPADTGKGYTLAQKMVGKACGLAGVRPGMYVEAETLTVGSQDTTGPMTRDEIKELAALSFSADLFMQSFCHTAAYPKPTDVKMHRSLPYFIMSRGGVALKPGDGVIHTWLNRMVLPDTLGTGGDSHTRFPIGCSFPAGSGLVAFAGVTGTMPLNMPESILVRFTGELQPGITLRDLVNAIPYVAIKKGLLTVEKKGKKNIFAGKVLEIEGLPQLKVEQAFELSDASAERSAAACTVRLDKEPVIEYLQSNVKLLGQMIEEGYGDAETLRRRIGKMEEWLAKPELLEPDADAEYAAVIEIDMNEITEPILACPNDPDDVATLSEILADEKRPKNIDEVFVGSCMTNIGHFRALGEVLRGKGQAKAKLWVVPPTKMDMKKLVEEGYYAVYGTAGARAEVPGCSLCMGNQARVADNAVVFSTSTRNFDDRMGKGAKVYLGSAELAAVCALLGHLPGREEYMEIAGSLSKNGDKVYRYLNFHEVTAQELQMLVD
>NZ_CP017305|1893226:1954285|1899035_1900058_+|WP_069810359.1|tRNA|DBSCAN-SWA
MKVNDFDYTLPDERIAAYPPEERGSTRLIVLDRAAQSITHSAYASLHEWLRPGDLLVLNNSKVIRARLVARKPTGARIELMLLEKHEGEQNLALYRGRLRVGDLLLAHGAELTVEALPSDGVARLSCATARLTDLFEAHGSVPIPPYLKRDAEELDRERYQTVFAELPGSVAAPTASLNLTDELLGKVRAKGVEIAHVTLHVGLGTFLPIRAESFEEHVMHREFYTIPEASARKIGATRAAGGRVVAVGTTVTRALEHAAPKLFDGGFSQEVSGEADIFIYPGYTFRIIDALLTNFHAPRSTVLMLTAAFAGTELLQRAYQQALDNGYRFLSYGDSMLVE
>NZ_CP017305|1893226:1954285|1912764_1913130_+|WP_069810368.1|DBSCAN-SWA
MKFTLDNIDGQLVGIAELEGRLDARNSKPLQKTFLEWLEKTPFLVFDCSLLDFIDSSGLGAIVGCLRKALEKEGDLRLAGMNEKVGMVFELTQAKRLFSIFSNGNEAALSFAAKPDSGTGR
>NZ_CP017305|1893226:1954285|1914864_1915284_+|WP_069810371.1|DBSCAN-SWA
MSKIITLTLPGERAFARMASQTASSIADFVTGDARQEPAGREFSHAFELAVSEAFTNSATHDDACANMPTVTLTFEFEERQLTVSVRDANEPFSIETPAPDIENYPENGYGLWIIRKVMDSVTYRREGNSNIISMSKTL
>NZ_CP017305|1893226:1954285|1916794_1917901_+|WP_084022370.1|DBSCAN-SWA
MRRTELFFSRRIRQTGAIPGDSRFRRASMLLCSLLMLMLSACNSISPKETTVSEKGESNFKTELPKKVQEFATPDRLKALDTQEVFQYRLGPGDMISIQVWRRPELSQEGILVSPDGFLSVPRIGNVQVLGMTVAEVKALVTSKLEFFYIEPEVTIRVQQFHNNKAFVLGRVSKPGVVNFPGKGTLLEALALAGGIPDQNKDTSLTKCAIIRGNDIIIWIDLQDLLRNGNMALNAPVRNNDVIYIPESSDEMVYVLGEVQTPGAIQIRSGMTVLKAVMLAGGINKNADPEKVFVIRQQTLKGDVIRVNLKSLLEKGDFSQNFNLMANDIVYVSPGGMTKLNYSIEKILPSMQILNLGVGQSSFIYGTP
>NZ_CP017305|1893226:1954285|1938906_1939872_-|WP_069810394.1|DBSCAN-SWA
MSQIFISYSHKDREFVKRLTNDLNVNLPDAQVLYDMLIQPGTSWAETLASQIEQADIVLAVLSPDYLASAWAEQELNVALERQLKNESFLLPLLIRPCNPTGFLSQLTWVDFTEDYGAGLANLIWGITGKRPKAAKGEVPGAPIKAVDPIEVESLRNQLQEAVELFKSRAAEPLPHQQFTEHVRAPEEKMRCFVVMPFGDEDLQVVYEDFVKPTLVDGCNLHCERGDDVFGSNIIMEDILKSIGTADVVLADLTRKNANVFYEVGICHALGKPVLLLAQSIDDVPFDLRHRRVLLYDYSPRGCKRLEGTLKQNMNAVLKDF
>NZ_CP017305|1893226:1954285|1934606_1935011_+|WP_069810387.1|DBSCAN-SWA
MSRIAGIEGIDEVHVEKLHGMGITTVEVLLEKGASPAGRKAIADATGMSHALVLRLVNPADLFRIKGIGKEYADLLEASGVDSVPELAQRRAENLHCKMSDVNTSKNLVKRLPTESEVEEWIAQAKSLPKVVTH
>NZ_CP017305|1893226:1954285|1949952_1951179_-|WP_069810407.1|transposase|DBSCAN-SWA
MPSLIAHYQQLLGLPETWKVSDVRLSMSGPRIEIHLEYIGPKVECPECGKAGRIYDLAPEQRWRHLDTMEYETHLIARVPRCECKEHRIKTIKVPWATRYSRYTLKFEALAVELLQECSSIQSASRLLRLNWHATNEIMNRAVKRGLSRRNKEAIAHLGLDEKSFRAGHQYVTILNDLKGGRVLEVVQSRTTDGAEALLLSFEASQRQGVKSISMDMWKPFAIAAKKHLPQADIVHDRFHISKYLNEAVDTVRRQESRQLHHAGDRTLIGSKFTWLRNPENMTESQRTSFDQLMACELKTGKAWSMKNMFREFWRLGCRESASFFFDYWSERVDQLALKPMIKVKELLKRHLDNILNYFEHEMTNAVSEGLNSKIQLYKASARGFHSFHSYRIRILFYCGKLNMAITG
>NZ_CP017305|1893226:1954285|1946876_1947305_+|WP_069810401.1|DBSCAN-SWA
MKQSILVLCTGNSCRSQMAEGFLRSFDPELEVFSAGTIPAGEVHPLAVQVMREAGIDISANRPKSVDEFLSRPFDYVVTVCDGANESCPMFSGEVKQRLHIGFDDPAGATGSSDEVLEVFRRVRDEIEARFGEFYRETIAGV
>NZ_CP017305|1893226:1954285|1940272_1940749_+|WP_084022450.1|DBSCAN-SWA
MKFEYHNTTHLVFGAGTLSRLGEVTSAYGKKAMIVTGGGSVKRNGTFDRAVASLKAAEVSVVECDGVEPNPRLSSVARGGEIARENGCDVVIALGGGSVMDSAKVMAAAVFYEGDLWEMFQHSQKTRRLPTKALPIITVPTLAATGSEMNSGAVIRVC
>NZ_CP017305|1893226:1954285|1906174_1907218_+|WP_069810363.1|transposase|DBSCAN-SWA
MEKIDIRKVSDRERALLRNQVIRLRKQGKGNNEVAELLGLSPETTSRWWQRYQREGQSMLAEPKRGRKHGEQRSLNPEQEKKIQKMIVDHYPEQLKLPFALWDRQAIQLLILQQFGINMPIRTVGHYLSRWGYTPQRPIRKAYEQRPAEVERWMQESYPAIKAKAKTENAEIYWADETGIATNGNLVRGYAPAGKTPELRLNARKEHISMISAINNQGKLRFMLYEDAMNSKRLIEFMKRLVKDAGRKVILILDNLKVHHSKPVKEWLGKHTEKIEVFYLPSYSPELNPDEYLNNDLKHAVHGNYGGVARSKAAIHDKTISHMRHLQKSPCKVEKLFDHPNVRYAKN
>NZ_CP017305|1893226:1954285|1908934_1910590_+|WP_069810365.1|DBSCAN-SWA
MKQRDELAILFVDDESDILHSLNRFLRREEYRKFFVDNAAEALDLLAGTPVDLVVSDLRMPGMNGLDLIKEVKRLYPGTLRMIVSGSQDIEQIIESVNKGEIFRFIPKPVEPESFKSILNDALDYYCMKLEHEELFDEISLKNGQLTEANTTLEKLASDLKRSEAQFRSMNDAAQDAVFMLDENGLIRYRNTAAEVMFGYRRSEHPAQPVSEIFPEPSTALELNDLVSCDSVLLARSCASLVIQIEGIRMDGSRLPLEISRGCVHLENGPHSVLIARDITTRIEEEKSRKHYETMQKELESQIEKKLLQSQAPITLRHIEISYLMHSSGHLDGDFTELIEYNPLQADLLIGDVMGHGIQSALVSAGMKSLFLKSIAEERNSPEALPPLERIVGRIHERCIHELIDLGMFATLLFLRLDLKYRQAVFVDCGHNPLIHLPSKTGRCRLVKGDNLPMGMIEEEEYRQSEFPIDENDLLVLYSDGITENRSPGGELFGIERFTALLEEHAALPTEAIVEKIEAALMCFCGCTNFADDVTCIVIRISGSTEIPDNG
>NZ_CP017305|1893226:1954285|1919107_1920022_+|WP_069810375.1|DBSCAN-SWA
MNEKVNIVFASDRNYIQHLSVALVSLLVNNRELAFTVYIISSGMTAKDRRNIDGIVKGYDCEVRHLTVSDDLFVTLATEHPMYPKGIYYRLLIPSLIDEEKVLYLDSDIVVNGSIRELYETDLGDAYVGAIEDPGFDRHDKLRMDKSAVYFNSGMMLINLRKWKETGLQQKIIDFIEKHPEDIWFPDQCGLNSVINGRWKKVALKFNQFSSLFDADFESRFDCFGKEELQEARTKPVVIHYTSGSKPWHFKNRHPYKSCYWKYLKMTPYRRAIYSDLRPLHLLKSMIPKEFKTAIKRVLKKQAG
>NZ_CP017305|1893226:1954285|1945266_1945572_+|WP_069810399.1|DBSCAN-SWA
MKEIKILGTGCAKCNQLADAVKAVVAAENIEADVQKVEDMQQIVSYGVMSTPGLVVDGKVACTGRVPSGDELRQMLTAAPKPSGCCGNHAKGIGRQNGTCC
>NZ_CP017305|1893226:1954285|1897746_1899033_+|WP_069810358.1|DBSCAN-SWA
MLTIYQFPQDEAALREQLNRTVSFDPDAQKTVDEILHRVRTEGDAAVLDYTERFQGVRLGDMRVPEAEIEAAYAEADPEFIAILEEAFANITAFHRHEAEKSFFYEQKGGVILGQRVTPMERALLYVPGGKAAYPSSVLMNAAPAKVAGVDEICMTTPCDAEGKVNPHILAAAKVAGVTQVYRLGGAQAVAAFAFGTESIPKVDIVTGPGNKYVALAKKQVFGHVAIDSIAGPSEVVVIADAGAEPEFIVMDMFAQAEHDPDASAVLITPSAELAAAVQEAAARLAGTMLRGEVITRALTDNGAIVVTSSMQEACQVSDMIAPEHLELHVDNPWEILPDLRQAGAIFMGPWSCETVGDYFAGPNHTLPTNGTARFFSPLSVRDFVKHTSIIAWSKGELARAGEKIARFADHEGLQAHAEAVRVRLKHL
>NZ_CP017305|1893226:1954285|1930377_1931451_+|WP_069810384.1|DBSCAN-SWA
MPINLPYLRRSFWRLLGNGSLPELCEKEWIVAPACVTTTRPALYLPGALDNVTASSASSNLEQEMRRIKGGRTEHAATIARALADVTLSDGYLYKRGLKIPVRIKKEQLVIERQPTAKKEVAVLACGLTDIQFFGHWMTDGLPLLMAARDLGPPIRNTAPLTGHQKEYLSMLNLGYDPFAAGKIGKLIVLEDYGQNNYKRERYQAMRARFREVAPKPAHPGSLLLRGTSGVVTPDAQGNRRILVNEEEIASYLQSIGFQLIDSTKQSAREIVEKTSGSKIIIGVEGSQIPHGLFTMADNGALINIFPPFHFNNVLKGQTDCMEMHYAFTIGEVCEGGFRLPLDTLKKTLDLVAAKTA
>NZ_CP017305|1893226:1954285|1935894_1936605_-|WP_169817627.1|DBSCAN-SWA
MKRVIAALVMILLLAGCCTTLVHHPGHDSTPRNEPEVAVNPPVPNRPGKPHRHSTNSIPPQPERVPVSKQNIEPESNISEEGRSAPAGSLVAVPDVIGKSLSRATIELNDSGFGIGRVSRDFIGEYAPGFVQSRLVVARQIPEPERRHPGGAKVDLYMETPAPVKAMILATILAAGGGGAAMAYKSKPVVKVAVHSDAGSQQFTAPSGLLGGNGFRLSLRHDPGVQKIRFKDRNAN
>NZ_CP017305|1893226:1954285|1920276_1922028_+|WP_069810376.1|DBSCAN-SWA
MSHKENAQKKLVSNAVSGILATLVYMLSRLLLTPFILHYLSLSEFGLWSLCFIILSYAGMGGFGVNSTYIRYAARYLAEGREEEISRLLSTGVAYMFLFCSLFYAGLSLAMPFLMVRFNVEVAQRAVATTLILGTAIVFSIELVLGGFRFIINGMHEFAKERMVTTVAGLVEIGAIIGFLALGSGVKGLLYAYALRLVLETLGCWFIAKSLLPSLRVSLRLFSREHLRHFFGFGGKVQVLGMLGIFLTAIDRLFITAISGLAAGGLFEIGRKLPSAAGGIASSAFGPFLSTAAHLEGKWTGDKWKTPAERAVTYLTVALSTVALAVAPIAFLDRVRLWLPFNSWIAALAAAGAGVLLLALLDRSFKTENRLESAELKKLYLDGIRFTNIINSLLFGFLIAMARPLIDVWVGTKYPGAVEVMIFLSIAYSIQLCTGPVTLLFRGIDRNGRELEYMLVQTLLMVLWIPAGTMAWGLTGAAAAIAASMSVSTLFIIWRSNGTFAIRVGEFFVHSVLPALIPVLPGVPIYAISQLWPQTGRLNLMIQILSCGTLFVLSSAGLLWKFVLDDAEKAKALELLPQKKASA
>NZ_CP017305|1893226:1954285|1938379_1938634_-|WP_069810392.1|DBSCAN-SWA
MSYRIEILRSARKQLEKIQESDRNRIIDSIRSLAEKPRPTGSKKLSGRQAWRIRIGSYRVIYEIQDSELIILVVTVGHRREVYR
>NZ_CP017305|1893226:1954285|1931736_1932957_+|WP_069810385.1|DBSCAN-SWA
MTRNTVAYLCSEYPAISHTFIYREIESLRKAGMTVYTASIHKPEKLDLMTTAEQEEAANTLMVLSQPATAIIAAHLHCLARNPGGYLKMAADAFRLLFKGPKNFVKAAAYFAEAGILLRWAHRHGITHIHEHFGNPTAIVAMLMKRYGGITFSISVHGPDIFYTVDSAMLPEKVREASFVRCISHYCRSQIMRISDVERWDRFHIVRCGIDPELYTPRPEPANAVPELLCVGRLTPAKGQHILIEACAMLDKANVPFHLTFVGDGPDRESLQNYTRTIGLDRKVTFTGALGQDKVRGHYDRADIFVLASFAEGVPVVLMEAMAKEIPVISTRITGIPELIEHGEDGLLAVPGDPEDLARQIRILLENGELRARYGQAGRRKVSAMYNQHQNNNLLVEHFKNELNDV
>NZ_CP017305|1893226:1954285|1938630_1938837_-|WP_069810393.1|DBSCAN-SWA
MIKVHPQYVVDERQQRTAVLLPLAEWEQILDYLEELDDIHAYDEAKTGSQEIMPFEQAVREIDEGSES
>NZ_CP017305|1893226:1954285|1905746_1906238_+|WP_169817626.1|DBSCAN-SWA
MNALQDSAGTIPYAPDKYTTVLIVDADPDSRSHTAASVEQLGYTALTADSDEACIELFGTCMIELLLLDINEPKKTGLKVLSWLREHGISVPVIIITSSSDIEQAIFSMNLGAYAYLLRPVSINRLGVINPANKTRKYIILRVWKKSILEKSLTGSALYCATR
>NZ_CP017305|1893226:1954285|1949104_1949290_-|WP_069810405.1|DBSCAN-SWA
MALYDELPVYCDVYVMILNIFEYTKEFPYKSTSGRLKLLDWPVSAPDSRMKALLTEPGVLD
>NZ_CP017305|1893226:1954285|1929205_1930306_+|WP_069810383.1|DBSCAN-SWA
MNEKRLDNPAYRNGRDLPEIDCVLIGVNSAKTLGRCIESIRSGSYPPEKLRICYADGGSTDESIAVAKRYDGVRVLALTPEYPTPGLGRNAGWKSGSAPLVQFLDSDTIVDPEWFHKAVARMRDARVGAVIGFRRELHPERSVYNWIGDLEWNGPVGESDCFGGDVLLRREALEATGGYDETLVGGEDPELSRRVIRAGWKIERIDAVMTRHDLAMTTVKQYLKRAYRSGYGFAAVRAREARLGSPFWKADFRKIAIKGGGFIAAESLAMVTLFAARPSLTSMLASATIGLAGVPLLFSPRLFKVGKFMRENQLGRKEAKIYAWHCSAVVLPQLAGVARYYAGAIAGRPLRNKRSALKTGLSQPET
>NZ_CP017305|1893226:1954285|1895142_1896291_+|WP_069810356.1|DBSCAN-SWA
MKIGISCHHTYGGSGAVATELGKALAMKGHTVHFFSQAAPFRLGLYSRNIHCHEIEAMNYPLFETPYHSLALASKIAEVAYYEKLDVVHAHYAIPHAISAMLARQMLEEKCPAAECFRIVTTLHGTDITIVGADRSMSDAVRLAINKSDGVTTVSGYLRDETIRMFTPRKKIEVIHNFVDTSVFQRLPGRRELLGIDEGKVVIHISNFRPVKRIMDVLAVFERVRREIPATLLLVGDGPDRSEAETWVRQQGIGESVRFLGKLNDIVPLLSIADLMLMPSNVESFGLAALEAMACGVPVVVTDAGGFPEFVRQGVDGFRHPHGDIEGMSRSALSILQDEAVWQRFSEAAVSQAGRFETALKVEEYEAFYRRLIDEAREREVQ
>NZ_CP017305|1893226:1954285|1948410_1948848_+|WP_069810403.1|DBSCAN-SWA
MEKKQHVLFLCTGNSARSQMAEGLLREMAGDRFVAMSAGLEPREEVHPLAVEVMREVGIDIASQKPKPVDLYLGRVPVHYLIVVCDKAQASCPRIWPGLLDGRRFFWPLPDPADQSGTREEQLAGFRAVRDELRGQLQEWVKSVE
>NZ_CP017305|1893226:1954285|1928103_1929198_+|WP_069810382.1|DBSCAN-SWA
MKVTELARMGLNHSRNALAESLYINTGVDFTRPVTFHALVNERCNCKCRHCEYWRQAEYIPEMSIEEWQKTLLSIKEFAGRFSVNFSGGEPFIKKGFIDLLRFCRDNDILAGVTTNGALLNEKNVQALVAARPFNLNISLDSTDARVHDYVRGMNGLFERIVRGIGLLKAEQQKQGVTFPIIIKPTVMSANFRELPEIVRWAEKIGATAVNFQPLGRWTPETYDELWIEEKEMAEFEEVIDRLVEMKRAGSPIMNSEEILRLMPASFREEKASPEHLPCRIGLHEFYIRPDGEVKLCFHFPSIGNTTKESAREIWTGAKAKKIREATIKCDKLCLLTCLSQKSLVNKASQALTMLTRQKTKAGQ
>NZ_CP017305|1893226:1954285|1951685_1952759_-|WP_169817628.1|DBSCAN-SWA
MLAVWLSSGVGVRVGLAVDESAKSDERIGLTNMVASNTYAGTRAENIGDGSLVSAWNAGDYAPQSVEFELEKKKNIITKMRLVPGQSPAGRTAHEVYAADSTGTYRMVARIEEYTSDGVPLVQEFLPPLHNVSKMMVKSVSSPSWIAWQEIEVYGIGSMAQFSPVSQAEARETEMFETAKKDAYSAASSKPLARYLSQGSKFSSEAKKVADEIAAYGLAQKGGRMGLQKYLTKYPDGYYSQSVRDKIAQEQRIAELKALVANNVKWKVSYQYETDEVMQIMFFRKNMWVTYKFILTGKVKQVDIKNETLLVQVSSATLDVPFAVSIKYLEYEKRAVSAYKSNALGKEIWIKYSDIMK
>NZ_CP017305|1893226:1954285|1935304_1935883_-|WP_069810388.1|DBSCAN-SWA
MDSKSFTLRDFFRDETIGEEAVSGLHSEEEVRELDHDTNDGDRHSRKSRALIRAVIGHVDDLLGIEVRDILLRAWEKYEDLAKYADPQRYSPDELVVLPLMEHAITSIHRPSIEVEFSRRLKKNIPFTITTEFSLSGFMLEIQAGKIMKIFAGQCQGSGSVCCMNTCLYRKESTKINLPGAIDLGEGIAIVA
>NZ_CP017305|1893226:1954285|1903222_1903444_+|WP_084022367.1|DBSCAN-SWA
MKKLFVFMFLLSSVSFVGCAQKAEQPAEAPAEAPAEAPAEAPAAAPAEAPAAAPAEAPAEQAAPAAAPAGEAK
>NZ_CP017305|1893226:1954285|1940860_1942345_+|WP_069808503.1|transposase|DBSCAN-SWA
MYQPKFQQLTFENFHLPFGGKLDPENRWVKLADVIPWHVAETMYAKNFMSKRGAPALTVRMALGSLIIKEKLGLSDIETVEQIKENPYLQFFIGLETYQHAAPFDASMLTHFRKRLKHTDLAALQEELLQRHLAEERRKAEERNQNDDGDGGSGNKGKLIVDATCAPADIAYPTDIGLLNEAREKTEKIIDQLCANAPQELGKPRTYRKKARKAFLSAIMKRNLSKKALRRAIRQQLQYIGRNLKHIEALSAAVPLTVLSTARYRDLLVIDELYRQQQEMYKSDRKSISDRIVSISQPHVRPIVRGKAAARTEFGMKLSISVVDGISLPERMSWNAYNEGCDLVRDIERYRERYGHYPESVHADKIYRTLANRMWCKARGIRLSGVPLGRPPKDVEKNRARRRQIREDEGVRNAVEGMFGKAKRRYGLGRVMARLAESSLSVVSITFLVMNLDRLLAAPFLRLFEWLLLELDVIRNLFAWSPPRAAIECRGAMA
>NZ_CP017305|1893226:1954285|1904004_1905231_-|WP_069808623.1|transposase|DBSCAN-SWA
MPSLITHYQQLLGLPETWKVSDVRLSTSGPRIEIHLEYIGPKVECPECGKAGRIYDLAPEQRWRHLDTMEYETHLIARVPRCECKEHRIKTIQVPWATRYSRYTLKFEALAVELLQECSSIQSASRLLRLNWHATNEIMNRAVKRGLSRRNKEAIAHLGLDEKSFRAGHQYVTILNDLKGGRVLEVVQSRTTDGAEALLLSFEASQRQGVKSISMDMWKPFAIAAKKHLPQADIVHDRFHISKYLNEAVDTVRRQESRQLHHAGDRTLIGSKFTWLRNPENMTESQRTSFDQLMACELKTGKAWSMKNMFREFWRLGCRESASFFFDYWSERVDQLALKPMIKVKELLKRHLDNILNYFEHEMTNAVSEGLNSKIQLYKASARGFHSFHSYRIRILFYCGKLNMAITG
>NZ_CP017305|1893226:1954285|1927686_1928091_+|WP_069810381.1|DBSCAN-SWA
MSTATEKYSESGYCSPSRLGTLWIAAFILALAGAFVPKPDFRYGFFMIDTLIHLALFAILAFIPMIFFRCRKTTFLLAISMAPLGYLLENLHVMVTGSNFDTINALANNLGVLAGIAAGFVLRLKSHYQRKRQS
>NZ_CP017305|1893226:1954285|1951267_1951558_-|WP_157098407.1|DBSCAN-SWA
MKKTTLLFLLSAMALPAAVQAGECYVKTTWPSGEPRSGVKIGGYISWGGMVENVYTNGNGEATLRWSGDRSLANIYIDGDDRGSCKNGASVEFVVK
>NZ_CP017305|1893226:1954285|1924329_1925469_+|WP_069810378.1|DBSCAN-SWA
MKHLPVLFGYHASNLGNSHVPLSLCRYWNESGRQATLTVASADDAFAFPWVTPALKGIKKGLVYKLGERMQPKQMTEALFFRKESASSPVYLWAGLSLDIFERFSERGAKIVLERINCHRATSRRIILSACEHWNEQVPETFSDSQIAEENRKLELSDAVFCPSPMVRKSMLDNGVAEAKLMQTSYGWAPERFPSIDAPRKENAEPVFLFTGTLCIRKGVMLLLEAWKKAKIRGKLLLCGGVYSDIEAAMERHRDTPNIEHIAYTKDIGEVYRRADLFVFPSLEEGGPMVTYEAMAHGIPPLVTAMGAGAVMRDGIDGIVLPDFDVDAWAAAMTEMAENREKRAEMGRNARQRAAEFTWKEVAARRAGLLEARYPELWK
>NZ_CP017305|1893226:1954285|1896450_1897479_-|WP_069810357.1|DBSCAN-SWA
MSFFGNLFRDIAIDLGTANTLIFIRNKGVVLNEPSIVARDRNTGKVVAIGQDALLMHEKTHPGIVTIKPLANGVIADYEATEELIRGLINRTKKQFSLGIRRMVIGIPSGITEVEKRAVRDSAEHVGAKEVYLVAEPMAAAIGIGIDVKEPMGNMIVDIGGGTTEIAVISLGGIASGESLRVAGTDITNAIIRHFRKAYNLAIGERTAEEVKIRIASAYKLDKELTMNVRGRNLVTALPEEREINSATIREAIATPISQIITSVKKSLEVTKPELSADILDRGLFLAGGGALIKGLDKKINEETKLMVHISEDPLTAVARGTGAVLEDLENYRSVLISTKRY
>NZ_CP017305|1893226:1954285|1893226_1894453_-|WP_069808569.1|transposase|DBSCAN-SWA
MPSLIAHYQQLLGLPETWKVSDVRLSMSGPRIEIHLEYIGPKVECPECGKAGRIYDLAPEQRWRHLDTMEYETHLIARVPRCECKEHRIKTIQVPWATRYSRYTLKFEALAVELLQECSSIQSASRLLRLNWHATNEIMNRAVKRGLSRRNKEAIAHLGLDEKSFRAGHQYVTILNDLKGGRVLEVVQSRTTDGAEALLLSFEASQRQGVKSISMDMWKPFAIAAKKHLPQADIVHDRFHISKYLNEAVDTVRRQESRQLHHAGDRTLIGSKFTWLRNPENMTESQRTSFDQLMACELKTGKAWSMKNMFREFWRLGCRESASFFFDYWSERVDQLALKPMIKVKELLKRHLDNILNYFEHEMTNAVSEGLNSKIQLYKASARGFHSFHSYRIRILFYCGKLNMAITG
>NZ_CP017305|1893226:1954285|1925488_1926019_+|WP_069810379.1|DBSCAN-SWA
MKTSDNTAPISATEPDWSRESPVPGRYEPAKNLLAAFRRYQRLKAKGGIMARALRPFVVLRHRFWSAVTGADIPLDSHIGGGLLLPHPNGIVIHPEARIGPNCLFFQQVTIGMGGRKPGAPVIGGHVDIGAGAKILGGVTIGDHALIGANAVVLCDVPPHATAVGIPARVIAPKKS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069808569.1|1893226_1894453_-|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_069810356.1|1895142_1896291_+	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_069810357.1|1896450_1897479_-	rod shape-determining protein	NA	NA	NA	NA
WP_069810358.1|1897746_1899033_+	histidinol dehydrogenase	NA	NA	NA	NA
WP_069810359.1|1899035_1900058_+|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_069810360.1|1900395_1902960_+	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_084022367.1|1903222_1903444_+	hypothetical protein	NA	NA	NA	NA
WP_069808623.1|1904004_1905231_-|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_169817626.1|1905746_1906238_+	response regulator	NA	NA	NA	NA
WP_069810363.1|1906174_1907218_+|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	5.6e-44	34.2
WP_084022368.1|1907195_1908938_+	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_069810365.1|1908934_1910590_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_084022369.1|1910639_1912067_+	WecB/TagA/CpsF family glycosyltransferase	NA	NA	NA	NA
WP_069810367.1|1912033_1912753_+	sugar transferase	NA	NA	NA	NA
WP_069810368.1|1912764_1913130_+	STAS domain-containing protein	NA	NA	NA	NA
WP_069810369.1|1913126_1914521_+	nucleoside-diphosphate-sugar pyrophosphorylase	NA	NA	NA	NA
WP_069810370.1|1914517_1914853_+	STAS domain-containing protein	NA	NA	NA	NA
WP_069810371.1|1914864_1915284_+	ATP-binding protein	NA	NA	NA	NA
WP_069810372.1|1915287_1916262_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_069810373.1|1916268_1916778_+	serine acetyltransferase	NA	NA	NA	NA
WP_084022370.1|1916794_1917901_+	SLBB domain-containing protein	NA	NA	NA	NA
WP_069810374.1|1917923_1919111_+	glycosyltransferase	NA	NA	NA	NA
WP_069810375.1|1919107_1920022_+	glycosyltransferase family 8 protein	NA	NA	NA	NA
WP_069810376.1|1920276_1922028_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_069810377.1|1922024_1924322_+	hypothetical protein	NA	NA	NA	NA
WP_069810378.1|1924329_1925469_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_069810379.1|1925488_1926019_+	serine acetyltransferase	NA	NA	NA	NA
WP_069810380.1|1926234_1927674_+	hypothetical protein	NA	NA	NA	NA
WP_069810381.1|1927686_1928091_+	hypothetical protein	NA	NA	NA	NA
WP_069810382.1|1928103_1929198_+	radical SAM protein	NA	NA	NA	NA
WP_069810383.1|1929205_1930306_+	glycosyltransferase	NA	NA	NA	NA
WP_069810384.1|1930377_1931451_+	glycosyltransferase family 61 protein	NA	NA	NA	NA
WP_069810385.1|1931736_1932957_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_069810386.1|1932956_1934159_+	glycosyltransferase	NA	NA	NA	NA
WP_069810387.1|1934606_1935011_+	DUF4332 domain-containing protein	NA	NA	NA	NA
WP_069810388.1|1935304_1935883_-	hypothetical protein	NA	NA	NA	NA
WP_169817627.1|1935894_1936605_-	PASTA domain-containing protein	NA	NA	NA	NA
WP_069810390.1|1936863_1937304_+	DUF937 domain-containing protein	NA	NA	NA	NA
WP_069810391.1|1937376_1938255_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_069810392.1|1938379_1938634_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A1C9M026	Mycobacterium_phage	2.9e-15	51.2
WP_069810393.1|1938630_1938837_-	hypothetical protein	NA	NA	NA	NA
WP_069810394.1|1938906_1939872_-	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_084022450.1|1940272_1940749_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_069808503.1|1940860_1942345_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_084022372.1|1942345_1943089_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_157098406.1|1943542_1944439_-	HNH endonuclease	NA	NA	NA	NA
WP_069810398.1|1944862_1945195_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069810399.1|1945266_1945572_+	thioredoxin family protein	NA	NA	NA	NA
WP_069810400.1|1945576_1946638_+	permease	NA	NA	NA	NA
WP_069810401.1|1946876_1947305_+	arsenate reductase ArsC	A0A2H4PQT9	Staphylococcus_phage	1.5e-19	42.5
WP_069810402.1|1947307_1948363_+	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_069810403.1|1948410_1948848_+	arsenate reductase ArsC	A0A2H4PQT9	Staphylococcus_phage	1.1e-12	33.6
WP_069810404.1|1948892_1949108_-	hypothetical protein	NA	NA	NA	NA
WP_069810405.1|1949104_1949290_-	hypothetical protein	NA	NA	NA	NA
WP_069810406.1|1949363_1949822_-	DUF1566 domain-containing protein	A0A0A0YR68	Pseudomonas_phage	2.2e-05	39.2
WP_069810407.1|1949952_1951179_-|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_157098407.1|1951267_1951558_-	hypothetical protein	NA	NA	NA	NA
WP_169817628.1|1951685_1952759_-	hypothetical protein	NA	NA	NA	NA
WP_069808503.1|1952800_1954285_-|transposase	IS5 family transposase	NA	NA	NA	NA