CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014859	Actinoalloteichus hymeniacidonis strain HPA177(T) (=DSM 45092(T)) chromosome, complete genome	19 crisprs	cas3,WYL,csa3,DinG,casR,DEDDh,cas4,cas5,cas8c,cas7,Cas9_archaeal,cas6e,cse2gr11,cas8e	1	46	1	0

1. NZ_CP014859

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014859_1

• CRISPR_ID: NZ_CP014859_1
• CRISPR_location: 364664-364848
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014859_1

Consensus_repeat	Method
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CRISPRCasFinder

spacers of NZ_CP014859_1

>1.1|364701|38|NZ_CP014859|CRISPRCasFinder
CCGGAACGACACCCGGAACCACGACACCCGAGACGGCG
>1.2|364776|35|NZ_CP014859|CRISPRCasFinder
ACCTGAACTTTACGCCGTAAAGATCGACAAGGATC

CRISPR arrays and Neighbor proteins around NZ_CP014859_1

CRISPR arrays

The CRISPR arrays of NZ_CP014859_1

>merge|NZ_CP014859|1|364664-364848|CRISPRCasFinder
GGCGCGATCCACACCGGCCAGTGAGGGCCGGTGTCACCCGGAACGACACCCGGAACCACGACACCCGAGACGGCGGTTGCGATCCTCACCGGCCTGTGAGGGCGGTGCCACGACCTGAACTTTACGCCGTAAAGATCGACAAGGATCAGTTGCGATCTCACCGGCCCGTGAGGGCCGGTGCCACC

>NZ_CP014859|1|1|364664-364848|CRISPRCasFinder
GGCGCGATCCACACCGGCCAGTGAGGGCCGGTGTCAC	CCGGAACGACACCCGGAACCACGACACCCGAGACGGCG
GTTGCGATCCTCACCGGCCTGTGAGGGCGGTGCCACG	ACCTGAACTTTACGCCGTAAAGATCGACAAGGATC
AGTTGCGATCTCACCGGCCCGTGAGGGCCGGTGCCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069846064.1|366548_366860_-|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|225209
NZ_CP014859.1|WP_069846060.1|358945_359296_+|Lsr2-family-protein	unknown	unknown	gnl|CDD|378714
NZ_CP014859.1|WP_069853176.1|363666_364662_+|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl|CDD|377028
NZ_CP014859.1|WP_069846079.1|374780_375278_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|178851
NZ_CP014859.1|WP_069853174.1|357334_358789_+|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778
NZ_CP014859.1|WP_084643523.1|352242_353757_+|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|379143
NZ_CP014859.1|WP_069846062.1|360938_363497_+|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl|CDD|214361
NZ_CP014859.1|WP_157420894.1|365688_366552_-|NAD-dependent-protein-deacetylase	unknown	unknown	gnl|CDD|223915
NZ_CP014859.1|WP_069846067.1|367529_368414_-|A/G-specific-adenine-glycosylase	unknown	unknown	gnl|CDD|224115
NZ_CP014859.1|WP_069846054.1|353905_354823_+|DUF2520-domain-containing-protein	unknown	unknown	gnl|CDD|227782
NZ_CP014859.1|WP_069846077.1|374031_374784_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
NZ_CP014859.1|WP_172803890.1|366948_367467_-|2'-5'-RNA-ligase-family-protein	unknown	unknown	gnl|CDD|379265
NZ_CP014859.1|WP_069846056.1|354819_355803_+|pantoate--beta-alanine-ligase	unknown	unknown	gnl|CDD|376824
NZ_CP014859.1|WP_157420896.1|372446_373217_-|hypothetical-protein	unknown	unknown	gnl|CDD|370709
NZ_CP014859.1|WP_084643524.1|359625_360495_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|274875
NZ_CP014859.1|WP_069846069.1|368740_370900_+|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|200604
NZ_CP014859.1|WP_069846057.1|355816_356347_+|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|376751
NZ_CP014859.1|WP_069846059.1|356388_357174_+|type-III-pantothenate-kinase	unknown	unknown	gnl|CDD|237347
NZ_CP014859.1|WP_069846071.1|370921_372304_-|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NZ_CP014859.1|WP_069846075.1|373504_373993_+|CarD-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224248

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069846064.1|366548_366860_-|antibiotic-biosynthesis-monooxygenase	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	2.53688e-25
NZ_CP014859.1|WP_069846060.1|358945_359296_+|Lsr2-family-protein	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	1.24935e-51
NZ_CP014859.1|WP_069853176.1|363666_364662_+|endonuclease/exonuclease/phosphatase-family-protein	gnl|CDD|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	1.2059e-19
NZ_CP014859.1|WP_069846079.1|374780_375278_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.0848e-76
NZ_CP014859.1|WP_069853174.1|357334_358789_+|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP014859.1|WP_084643523.1|352242_353757_+|PrsW-family-intramembrane-metalloprotease	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	1.203e-53
NZ_CP014859.1|WP_069846062.1|360938_363497_+|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl|CDD|214361	CHL00095, clpC, Clp protease ATP binding subunit.	0
NZ_CP014859.1|WP_157420894.1|365688_366552_-|NAD-dependent-protein-deacetylase	gnl|CDD|223915	COG0846, SIR2, NAD-dependent protein deacetylases, SIR2 family [Transcription].	2.80784e-31
NZ_CP014859.1|WP_069846067.1|367529_368414_-|A/G-specific-adenine-glycosylase	gnl|CDD|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	2.23353e-96
NZ_CP014859.1|WP_069846054.1|353905_354823_+|DUF2520-domain-containing-protein	gnl|CDD|227782	COG5495, COG5495, Uncharacterized conserved protein [Function unknown].	2.41484e-53
NZ_CP014859.1|WP_069846077.1|374031_374784_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	2.97188e-78
NZ_CP014859.1|WP_172803890.1|366948_367467_-|2'-5'-RNA-ligase-family-protein	gnl|CDD|379265	pfam13563, 2_5_RNA_ligase2, 2'-5' RNA ligase superfamily. This family contains proteins related to pfam02834. These proteins are likely to be enzymes, but they may not share the RNA ligase activity.	2.1726e-05
NZ_CP014859.1|WP_069846056.1|354819_355803_+|pantoate--beta-alanine-ligase	gnl|CDD|376824	pfam02569, Pantoate_ligase, Pantoate-beta-alanine ligase. Pantoate-beta-alanine ligase, also know as pantothenate synthase, (EC:6.3.2.1) catalyzes the formation of pantothenate from pantoate and alanine.	1.72149e-139
NZ_CP014859.1|WP_157420896.1|372446_373217_-|hypothetical-protein	gnl|CDD|370709	pfam09805, Nop25, Nucleolar protein 12 (25kDa). Members of this family of proteins are part of the yeast nuclear pore complex-associated pre-60S ribosomal subunit. The family functions as a highly conserved exonuclease that is required for the 5'-end maturation of 5.8S and 25S rRNAs, demonstrating that 5'-end processing also has a redundant pathway. Nop25 binds late pre-60S ribosomes, accompanying them from the nucleolus to the nuclear periphery; and there is evidence for both physical and functional links between late 60S subunit processing and export.	0.0045665
NZ_CP014859.1|WP_084643524.1|359625_360495_-|(2Fe-2S)-binding-protein	gnl|CDD|274875	TIGR03951, Fe_III_red_FhuF, siderophore-iron reductase FhuF. Members of this protein family, including FhuF of E. coli, are siderophore ferric iron reductases that appear to play a role in iron removal from certain hydroxamate-type siderophores, including coprogen, ferrichrome, ferrioxamine B, and aerobactin. Genes occur in regularly in siderophore transport and/or biosynthesis clusters. The C-terminus includes four Cys residues in a C-C-10(X)-C-X-X-C motif that binds a 2Fe-2S cluster. Family TIGR03950 is similar, but especially in the C-terminal region, but likely acts on a different panel of siderophores. [Energy metabolism, Electron transport, Transport and binding proteins, Cations and iron carrying compounds].	5.19619e-06
NZ_CP014859.1|WP_069846069.1|368740_370900_+|trypsin-like-serine-protease	gnl|CDD|200604	cd11308, Peptidase_M14NE-CP-C_like, Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain. This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.	0.0072729
NZ_CP014859.1|WP_069846057.1|355816_356347_+|aspartate-1-decarboxylase	gnl|CDD|376751	pfam02261, Asp_decarbox, Aspartate decarboxylase. Decarboxylation of aspartate is the major route of beta-alanine production in bacteria, and is catalyzed by the enzyme aspartate decarboxylase EC:4.1.1.11 which requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. This family contains both chains of aspartate decarboxylase.	2.47756e-78
NZ_CP014859.1|WP_069846059.1|356388_357174_+|type-III-pantothenate-kinase	gnl|CDD|237347	PRK13318, PRK13318, type III pantothenate kinase.	8.40274e-129
NZ_CP014859.1|WP_069846071.1|370921_372304_-|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP014859.1|WP_069846075.1|373504_373993_+|CarD-family-transcriptional-regulator	gnl|CDD|224248	COG1329, COG1329, Transcriptional regulators, similar to M. xanthus CarD [Transcription].	2.40048e-69

Protein sequences

>NZ_CP014859.1|WP_069853176.1|363666_364662_+|endonuclease/exonuclease/phosphatase-family-protein
MAYEDPAEAEETGRRRPGGPLVTLLLLLLTVPFVLVSVNRLIEVGGLRIAVGAAALTPYTLPLGLLLIVAGFALRRWAVALVAAVLTVIMAAVVIPRATPDARPFVQGESVRVLSLNMRYGSADPAVLVDLVRDRQVDVLSLQELTPAAVTALAEAGIESELPHQVIDPENGAPGSGLYSRHEAERIDAIPATHRQSAAAVTLPDGGEFEIVSVHPLWPIGDGTTDTWQRELASLPEARSADPIRVLAGDFNATLDHGPLRRLLNSGYQDAADQTGDGLRPTWPAGGTITAPPLTIDHVLVDNRCAVESFDVLDVPGSDHRAVLAEFVVPS
>NZ_CP014859.1|WP_069846062.1|360938_363497_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGIALEGVRQQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVLQLLSGYQGKEPAETGGRGEGTPSSSLVLDQFGRNLTSSAREGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQNIVKGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDEIHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKHVEKDPALERRFQPIQVGEPTMEQTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIADVRRDKESAIDAQDFERAARLRDEEKQLLGQKAEREKQWKSGDLDVVAEVDDEQIAEVLANWTGIPVFKLTEEETTRLLRMEEELHKRIIGQEDAVKAVSQAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGEDDALIQIDMGEFHDRYTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEVYNTLLQVLEDGRLTDGQGRTVDFKNTVIIFTSNLGTQDISKAVGLGFAGGGTEGSNYDRMKQKVNDELKKHFRPEFLNRIDDIIVFHQLTEDEIIRMVDLMIARVETQLKNKDMSLELTANAKKLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFGELEAGHIIIGDVEGFEEGKSDDKARFVFRGEPKPSQVPDVPPVELSSSTGGNQELPPAEGESE
>NZ_CP014859.1|WP_084643524.1|359625_360495_-|(2Fe-2S)-binding-protein
MTTAFRRSGAYGSGTAANIAESIARLDLPPWLEARHGDAALDAGWSRCSSLLDDPASFTRWRELLSGWLIENYGAAPERTTAGYVMSWYLSVPGYLGALLFHTARRVPSLAPEHTAFRLAEGRPHLDGIALTGEAFACLPDDPAAHTSAATVVADEHALADLLRARFAGHAARFVAAFAPGTRLGRRMLWAAATDVLDTTLWLAGQMCGDEDGGVADAALVLGTAADPLLDPFTSVSTMYRVSVDDGERWTRRRGSCCFHYALPGSPQACTTCPRVGTAERDARVRELG
>NZ_CP014859.1|WP_069846060.1|358945_359296_+|Lsr2-family-protein
MAQKVTVTLVDDLDGSKADETVEFTFDGAAYQIDLSSANAGVLRDALAGFVGHARRSGGRKRNVRPGGDRADGGSTSAGDREQNQAIREWARKRGMKVSDRGRIPADVIDAYHAAN
>NZ_CP014859.1|WP_069853174.1|357334_358789_+|lysine--tRNA-ligase
MKVRREKRSRLLESGIEPYPVVLPITHTVAAIRAKHTDLEPDTATGEIVGISGRVMFLRNTGKLCFATLRSGDGSELQAMLSLAQIGAESLASWKADVDLGDHVFVHGEVITSRRGELSVMADEWRIAAKALRPLPVTHKELSEETRVRQRYVDLIVRPQARRIVETRAAVVRSLRESFHRHGFTEVETPMLQTLYGGAAARPFHTHSNAFDIDLYLRIAPELYLKRCVVGGMERVFEINRNFRNEGSDSSHSPEFAMTEFYQAYSDYNDIATLTRELIQEAARAACGGEVVTLIDGTEYDLSGEWKWLSMYGSLAEKVGEEVTPDTSVERLRAIAAEQGLEHDPALGHGKLIEELWEHLIGDHLYEPTFVKDFPIETSPLTRQHRTEPGVAEKWDLYIRGFELATGYSELVDPVVERERLEAQARLAAGGDVEAMRLDEDFLRALEYGMPPTGGCGMGVDRLLMALTGAGIRETILFPLVRPE
>NZ_CP014859.1|WP_069846059.1|356388_357174_+|type-III-pantothenate-kinase
MLLTIDVGNTNIVFGLYVGSGPDARLLRDWRMRTDARMTADELAWTMRGLLGEHADRITGISALSTVPAVARELRVMLARYYAEVPTLIVAPGVRTGVPLLVDNPKEVGGDRVVNTLAAHHLYDTACVVVDFGTSTNIDVISRKGEFLGGVFAPGIEISVDALAARAAQLRKVELLRPRNVIGKNTVECLQSGILFGFAGQVDGLVRRILAELSAGEHGPVTVLATGGLAPLVIGESETITTHVPDLTLIGLRLVYERNMS
>NZ_CP014859.1|WP_069846057.1|355816_356347_+|aspartate-1-decarboxylase
MLRTMLKSKIHRATVTQADLHYVGSVTVDEDLMDAADLLAGEQVAIVDVTNGARLETYVIPGERGTGVLGINGAAAHLVHPGDLVILIAYGLMDAAEIREHRPSVVFVDADNKVISLDADPAVVPDGFGLSSGSIDSRSADSAPTAGGSTTARSESIAAGETDDAVRLDALLQSER
>NZ_CP014859.1|WP_069846056.1|354819_355803_+|pantoate--beta-alanine-ligase
MTETQATPGAPGESPLFAPGDTTVHSDPAQLARVTRALRATGRRIVLVPTMGALHRGHRELIRRAKRVPNTIVVVSIFVNPRQFGAGEDFERYPRDLDTDVAVCRAEQVELVFAPTAAAMYGAGTSITVSAGPLGDELEGASRPGHFAGVLTVVAKLLNIVRPDFAFFGEKDYQQLVLLRRMGRELDFDASIVGIPTIREHDGLALSSRNVYLDAEARNAAVVLSAALTAGVYAARSGGDAARVLATAREVLDGEPALDVDYLELRDVELNAVDEQREARLLVAARVGAVRLIDNVAIAFGTAEEQPGEVADAPAADGAATDSAESR
>NZ_CP014859.1|WP_069846054.1|353905_354823_+|DUF2520-domain-containing-protein
MIDNAGVRPARLAVGVISAGRVGAVLGASLARAGHVVVATSAVSDASLRRAEQLLPDVPVLAPDEVATRADLVMLAVPDDVLPGMVAGLVATGALRAGQIVAHTSGAHGVDVLTPAAELGALPLALHPVMTFTGRSEDLERLAACCIGVTASGDPNSPVEPGWNVGEALVVEIGAEPVRIPEAVRPLYHAALAHGANHLITLLTECVGLLSQAGVAHPERLLGPLCGAAMDNALRHGDRALTGPVARGDLSTLRTHLDVLGEVAPEVVPSYRVLAARTADRARAAGLLSDSTAAEVDDLLNEEPR
>NZ_CP014859.1|WP_084643523.1|352242_353757_+|PrsW-family-intramembrane-metalloprotease
MTSSQASRWQRFLLPVLGVVILGLCGLTLLGLTHARVGAVALVVGAAAALLPLGPVIATFLWVDRWEPEPPRLLFAAFLWGACGATIAALLINDTAQVVGEVLLGTGGGDLVAALISAPLFEEAAKGLFVLAVLLRRRQEFNGIVDGIVYAGITGVGFAFTENITYFGLAFVQGGFGDMSGGVVAVFVLRGVLSPFTHSLFGAMLGIGLGIAACTSRPRMRIAAPLIGYLMAVLLHALWNGAATLGGGRIFINVYFLVMVPIFLSTALLVCWQRRREQHVVVTQLPGFAAEGWIAASEIGLLASLTSRKEWRVAVRKRSGASAGKAVAAYQLAVTELAFVRNQLAGGRTFPETAERLDQAVARLIRSRAAVLRSPGALADAARSTAGIRRRNRPSRGSGWLFDRQPVLLRALGPPRRPVSTEVTLPGIVVGSNRSADETLPIPKMVLEPLSSGAPTVRHDGVVAPVEPALTSAREPVIPAQSSESTDVTVVIDPVPPTSGEPKA
>NZ_CP014859.1|WP_157420894.1|365688_366552_-|NAD-dependent-protein-deacetylase
MSTDPIREAADLIADAEALLICAGAGFGVDSGLPDFRGPEGFWRAYPAYRSLGLDFAELADPVHFAADPALAWGFYGHRLDLYRRTTPHAGFGTLHRWGTALPGGFRVFTSNVDGQFQRAGFAEETIVERHGSIHRLQCTGPCAQRQWPADEVQVDLDEETMRARGPLPSCPDCGGLARPNILMFGDHSWVADHTSTAMDGLTTWLRPLRTARLVVIELGAGTAVPTVRRQAELASAARGALIRINLREPAIRHGRGIEIPMGAAAAIAAIDELLPDRLRAAVETAG
>NZ_CP014859.1|WP_069846064.1|366548_366860_-|antibiotic-biosynthesis-monooxygenase
MAVVKINAIEVPEGSGPELEKRFAARQGAVENAPGFLAFELLRPVAGENRYFVYTRWESEEAFQAWSGGPAKEAHSGERSKPVASGASLLEFEVIQHAESKGE
>NZ_CP014859.1|WP_172803890.1|366948_367467_-|2'-5'-RNA-ligase-family-protein
MTLDFFFDDASDRTIRDLWQRLADIGARPVPGSTHPAPHVRFAAAAEIAPRVRQDLRAELRALSLPSFWLTTLGTFATSAPVLMLGAVVDAELLAVHSTVHDVLAGRVKQPSAYYLPGSWVPHCPLAEGVEREALAAGFAELHPVRAIHARVVGVGVVDGRTGHTEDLVRLG
>NZ_CP014859.1|WP_069846067.1|367529_368414_-|A/G-specific-adenine-glycosylase
MKSTVLAPTTLIAWFDRTGRDLPWRHPETTGWGVLVSEIMLQQTPVVRVQPIWQDWMQRWPKPSSLAEATAADVLRAWGKLGYPRRALRLHAAAAAIAKNHGDVVPSDVDTLLALPGIGAYTARAVAAFAYGRRAPVVDTNVRRVVARAVHGSAEAGPPSTTRDLADVDTLLPEEDARAARYSAALMELGALVCTARNPTCVDCPVRVDCAWQQAGKPAYAGPTRPTQRFAGTDRQVRGLLLDVLRGASGPVERAKLDLVWQHDGQRDRCLDSLLVDGLAEQTEDGLFALPGES
>NZ_CP014859.1|WP_069846069.1|368740_370900_+|trypsin-like-serine-protease
MKQARLVASVLAAGVLAAGSIFGATPRGIAQQSDMSDLSAADQAANYPASLEVAIERDLATDPITYASNSLAAADASATADALRDQLADNFGGAWFDPAAGRLNVAVTSQGAADMVRQRGAEAHIRGVNEERLIEVSADLRAWIDGLPAERRALIYGLSTSAKTSSVTLAFSATSAGRSLAAELPGDHGVELNTEFVLEPPQTQQAADLLGGQGISAAAEDGSELASCSLGFNAIDGQGRALALTSGHCATDAATILAADGTEIGVPERVAWNSIADGDDGDDYASVRVQNPNLIAQPAVTDWQGGTLPVEGVVAPIEGMQVCHSGQTSQWECGQIQQVDVEVRVNGPDGTVKSQRSFWYDACTERGDSGGAVLAGTLAVGLHSAGALTPDDRRCLSTIGEQNIAFAEPLATDVIGDFGDDLRVLTTTADTDGDGVPDHEELAADRTTVHDANGDGVPAFLDPDEPTLGVPVVTSPEDGSRHTERSLPIVGTSKPGATVTVTYRGQSHLVTADDRGEWRLPAEEQLALGHYEITVSQSWTATNGSQWQSGETTSGFFIAPGPPAITSPQDGAEIDETAPMIFGTGEPGAVVELTVDDVDLGTASVVDDNGEWSITLVEPLSHGSHTIAAVQLVEDVGSNPTSITITVLPSEGGHTTVIPEAPGGPGANPPTGGDPDLADTGVSVALLALLGTAGLVAGTLLMLRRRREQLGVAGQTEAD
>NZ_CP014859.1|WP_069846071.1|370921_372304_-|DNA-repair-protein-RadA
MAPTKSAKPARPRYRCGECGLEVPKWVGRCPECQAWGSIDETAAPSRSSLSRVAAGAPATPARPIADVDVEAARARPTGVPELDRVLGGGIVPGAVVLLAGEPGVGKSTLLLEVAHQWAAGPGGPALYITGEESAGQVRLRAERTGNVHESLYVSAESDLSAVLGHVDAVRPGLLILDSVQTVQSPEVEGSPGGVTQVRAVTVALTALAKERGLPVVLVGHVTKDGSVAGPRVLEHLVDVVLHFEGDRHSTLRMVRGVKNRFGPADEVGCFELADDGIVGLADPSGLFLNRRETAVAGTAVTVVVEGKRPLLAEVQALVSKSTLAMPRRAVSGLDSARVSMILAVLERRGRVRLGESDVFTATVGGMKVNEPASDLAVALAVASAANDRPLPPDLAVVGEVGLAGEIRRVAGAGRRFAEAARLGFTRALVPPDSGPLPPELRAVVVPDLRAALAELRRGD
>NZ_CP014859.1|WP_157420896.1|372446_373217_-|hypothetical-protein
MRRAEQTVRRGIGTGSARRRLVPVALAAGIALIAGGCSAGQITQTSRKEPIIDGINGDVGDMAIRDAQLLFPVGEDPRYEAGDSVPLSVTLVNTGSVTDTLVEITSPSAQVVQVQGDTVIPGGTSIVATVDPRDWTDAQRQLAEQQESADASGTPGDTEDEDGENQDSEDAENQDGDQDNTTGDETSPSDQPESSANRQPLEDNVITVVLDELVNDVQAGTNLEVVFVFENAGQISLQVPLGPPAEGRPVEQNDEH
>NZ_CP014859.1|WP_069846075.1|373504_373993_+|CarD-family-transcriptional-regulator
MVFKVGETVVYPHHGAALIEAIETRVIKGEEKKYLVLKVAQGDLTVRVPADNAEIVGVRDVVGQEGLNRVFEVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRREKDRGLSAGEKRMLAKARQILVSELALAEGTDEGKAEILLDEVLETAS
>NZ_CP014859.1|WP_069846077.1|374031_374784_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MSVIAVVPAAGRGERLGAQVPKALVEVAGEPLLVHAVHGLLSAGCVDHVVVAAPAAEVSVVVAAVERFGSQVSVVVGGAERGDSVRLALRSGLTVLPGARVVLVHDAARAFTPVEVIRSVVDAVRSGLPAVIPVLPVADTVKQIDSTGRVVATPDRAGLRLVQTPQGFDVDVLRKAYGLDSDPDGASPMSILNTDDAGLVEQSGIPVHIVAGHSHAFKVTTPFDLAVVDAMLAQKAVAAERADETVGEAR
>NZ_CP014859.1|WP_069846079.1|374780_375278_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MTELSALAVPRVGLGTDVHPIQEGKDCWLAGLHWPDATGCAGHSDGDVAAHALCDAMLGAVALGDLGSVFGTSAPEWAGAHGVALLGEVRRRFEAAGYRLGNAVVQIIGNAPRIGPRREEAQRVLSEAAGGPVSVTATTTDGLGLTGRGEGVAAIATALLVPVQG

Crispr_ID: NZ_CP014859_2

• CRISPR_ID: NZ_CP014859_2
• CRISPR_location: 364885-365495
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of NZ_CP014859_2

Consensus_repeat	Method
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CRT
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	PILER-CR
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CRISPRCasFinder

spacers of NZ_CP014859_2

>2.1|364922|19|NZ_CP014859|CRT
TGAGGACGACGATGCCGGG
>2.2|364978|37|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder
CGACGTCGGCGGCGGCACCGGAGCTGATCTTGTTGGC
>2.3|365052|38|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder
GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
>2.4|365127|36|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder
CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
>2.5|365200|37|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder
GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA
>2.6|365274|38|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder
GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
>2.7|365349|36|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder
CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
>2.8|365422|37|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder
GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA

CRISPR arrays and Neighbor proteins around NZ_CP014859_2

CRISPR arrays

The CRISPR arrays of NZ_CP014859_2

>merge|NZ_CP014859|2|364885-365495|CRT,PILER-CR,CRISPRCasFinder
GTTGCGATCCTCACCCACACCTCCTTGCCGCGAGCAGTGAGGACGACGATGCCGGGGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCACCGACGTCGGCGGCGGCACCGGAGCTGATCTTGTTGGCGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCACGTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTGGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCACCGGCATTGCCTGGAATCGACTCACCCGAAACTAACTGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCACGCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCAGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCACGTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTGGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCACCGGCATTGCCTGGAATCGACTCACCCGAAACTAACTGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCACGCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCAGTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC

>NZ_CP014859|2|1|364885-365495|CRT
GTTGCGATCCTCACCCACACCTCCTTGCCGCGAGCAG	TGAGGACGACGATGCCGGG
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGACGTCGGCGGCGGCACCGGAGCTGATCTTGTTGGC
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC

>NZ_CP014859|2|1|364941-365495|PILER-CR
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGACGTCGGCGGCGGCACCGGAGCTGATCTTGTTGGC
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC

>NZ_CP014859|2|2|364941-365495|CRISPRCasFinder
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGACGTCGGCGGCGGCACCGGAGCTGATCTTGTTGGC
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GTCGAGCGAACGACCGAGGTCACTCGGCACACGATCTG
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	CGGCATTGCCTGGAATCGACTCACCCGAAACTAACT
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC	GCCGCACCGAGGGTCAGCGTCGCCTCGGTCTCCCGCA
GTTGCGATCCTCACCGGCCCTCACGGGCCGGTGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069846064.1|366548_366860_-|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|225209
NZ_CP014859.1|WP_069846060.1|358945_359296_+|Lsr2-family-protein	unknown	unknown	gnl|CDD|378714
NZ_CP014859.1|WP_069853176.1|363666_364662_+|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl|CDD|377028
NZ_CP014859.1|WP_069846079.1|374780_375278_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|178851
NZ_CP014859.1|WP_069853174.1|357334_358789_+|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778
NZ_CP014859.1|WP_084643523.1|352242_353757_+|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|379143
NZ_CP014859.1|WP_069846062.1|360938_363497_+|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl|CDD|214361
NZ_CP014859.1|WP_157420894.1|365688_366552_-|NAD-dependent-protein-deacetylase	unknown	unknown	gnl|CDD|223915
NZ_CP014859.1|WP_069846067.1|367529_368414_-|A/G-specific-adenine-glycosylase	unknown	unknown	gnl|CDD|224115
NZ_CP014859.1|WP_069846054.1|353905_354823_+|DUF2520-domain-containing-protein	unknown	unknown	gnl|CDD|227782
NZ_CP014859.1|WP_069846077.1|374031_374784_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
NZ_CP014859.1|WP_172803890.1|366948_367467_-|2'-5'-RNA-ligase-family-protein	unknown	unknown	gnl|CDD|379265
NZ_CP014859.1|WP_069846056.1|354819_355803_+|pantoate--beta-alanine-ligase	unknown	unknown	gnl|CDD|376824
NZ_CP014859.1|WP_157420896.1|372446_373217_-|hypothetical-protein	unknown	unknown	gnl|CDD|370709
NZ_CP014859.1|WP_084643524.1|359625_360495_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|274875
NZ_CP014859.1|WP_069846069.1|368740_370900_+|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|200604
NZ_CP014859.1|WP_069846057.1|355816_356347_+|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|376751
NZ_CP014859.1|WP_069846059.1|356388_357174_+|type-III-pantothenate-kinase	unknown	unknown	gnl|CDD|237347
NZ_CP014859.1|WP_069846071.1|370921_372304_-|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NZ_CP014859.1|WP_069846075.1|373504_373993_+|CarD-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224248

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069846064.1|366548_366860_-|antibiotic-biosynthesis-monooxygenase	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	2.53688e-25
NZ_CP014859.1|WP_069846060.1|358945_359296_+|Lsr2-family-protein	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	1.24935e-51
NZ_CP014859.1|WP_069853176.1|363666_364662_+|endonuclease/exonuclease/phosphatase-family-protein	gnl|CDD|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	1.2059e-19
NZ_CP014859.1|WP_069846079.1|374780_375278_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.0848e-76
NZ_CP014859.1|WP_069853174.1|357334_358789_+|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP014859.1|WP_084643523.1|352242_353757_+|PrsW-family-intramembrane-metalloprotease	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	1.203e-53
NZ_CP014859.1|WP_069846062.1|360938_363497_+|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl|CDD|214361	CHL00095, clpC, Clp protease ATP binding subunit.	0
NZ_CP014859.1|WP_157420894.1|365688_366552_-|NAD-dependent-protein-deacetylase	gnl|CDD|223915	COG0846, SIR2, NAD-dependent protein deacetylases, SIR2 family [Transcription].	2.80784e-31
NZ_CP014859.1|WP_069846067.1|367529_368414_-|A/G-specific-adenine-glycosylase	gnl|CDD|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	2.23353e-96
NZ_CP014859.1|WP_069846054.1|353905_354823_+|DUF2520-domain-containing-protein	gnl|CDD|227782	COG5495, COG5495, Uncharacterized conserved protein [Function unknown].	2.41484e-53
NZ_CP014859.1|WP_069846077.1|374031_374784_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	2.97188e-78
NZ_CP014859.1|WP_172803890.1|366948_367467_-|2'-5'-RNA-ligase-family-protein	gnl|CDD|379265	pfam13563, 2_5_RNA_ligase2, 2'-5' RNA ligase superfamily. This family contains proteins related to pfam02834. These proteins are likely to be enzymes, but they may not share the RNA ligase activity.	2.1726e-05
NZ_CP014859.1|WP_069846056.1|354819_355803_+|pantoate--beta-alanine-ligase	gnl|CDD|376824	pfam02569, Pantoate_ligase, Pantoate-beta-alanine ligase. Pantoate-beta-alanine ligase, also know as pantothenate synthase, (EC:6.3.2.1) catalyzes the formation of pantothenate from pantoate and alanine.	1.72149e-139
NZ_CP014859.1|WP_157420896.1|372446_373217_-|hypothetical-protein	gnl|CDD|370709	pfam09805, Nop25, Nucleolar protein 12 (25kDa). Members of this family of proteins are part of the yeast nuclear pore complex-associated pre-60S ribosomal subunit. The family functions as a highly conserved exonuclease that is required for the 5'-end maturation of 5.8S and 25S rRNAs, demonstrating that 5'-end processing also has a redundant pathway. Nop25 binds late pre-60S ribosomes, accompanying them from the nucleolus to the nuclear periphery; and there is evidence for both physical and functional links between late 60S subunit processing and export.	0.0045665
NZ_CP014859.1|WP_084643524.1|359625_360495_-|(2Fe-2S)-binding-protein	gnl|CDD|274875	TIGR03951, Fe_III_red_FhuF, siderophore-iron reductase FhuF. Members of this protein family, including FhuF of E. coli, are siderophore ferric iron reductases that appear to play a role in iron removal from certain hydroxamate-type siderophores, including coprogen, ferrichrome, ferrioxamine B, and aerobactin. Genes occur in regularly in siderophore transport and/or biosynthesis clusters. The C-terminus includes four Cys residues in a C-C-10(X)-C-X-X-C motif that binds a 2Fe-2S cluster. Family TIGR03950 is similar, but especially in the C-terminal region, but likely acts on a different panel of siderophores. [Energy metabolism, Electron transport, Transport and binding proteins, Cations and iron carrying compounds].	5.19619e-06
NZ_CP014859.1|WP_069846069.1|368740_370900_+|trypsin-like-serine-protease	gnl|CDD|200604	cd11308, Peptidase_M14NE-CP-C_like, Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain. This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.	0.0072729
NZ_CP014859.1|WP_069846057.1|355816_356347_+|aspartate-1-decarboxylase	gnl|CDD|376751	pfam02261, Asp_decarbox, Aspartate decarboxylase. Decarboxylation of aspartate is the major route of beta-alanine production in bacteria, and is catalyzed by the enzyme aspartate decarboxylase EC:4.1.1.11 which requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. This family contains both chains of aspartate decarboxylase.	2.47756e-78
NZ_CP014859.1|WP_069846059.1|356388_357174_+|type-III-pantothenate-kinase	gnl|CDD|237347	PRK13318, PRK13318, type III pantothenate kinase.	8.40274e-129
NZ_CP014859.1|WP_069846071.1|370921_372304_-|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP014859.1|WP_069846075.1|373504_373993_+|CarD-family-transcriptional-regulator	gnl|CDD|224248	COG1329, COG1329, Transcriptional regulators, similar to M. xanthus CarD [Transcription].	2.40048e-69

Protein sequences

>NZ_CP014859.1|WP_069853176.1|363666_364662_+|endonuclease/exonuclease/phosphatase-family-protein
MAYEDPAEAEETGRRRPGGPLVTLLLLLLTVPFVLVSVNRLIEVGGLRIAVGAAALTPYTLPLGLLLIVAGFALRRWAVALVAAVLTVIMAAVVIPRATPDARPFVQGESVRVLSLNMRYGSADPAVLVDLVRDRQVDVLSLQELTPAAVTALAEAGIESELPHQVIDPENGAPGSGLYSRHEAERIDAIPATHRQSAAAVTLPDGGEFEIVSVHPLWPIGDGTTDTWQRELASLPEARSADPIRVLAGDFNATLDHGPLRRLLNSGYQDAADQTGDGLRPTWPAGGTITAPPLTIDHVLVDNRCAVESFDVLDVPGSDHRAVLAEFVVPS
>NZ_CP014859.1|WP_069846062.1|360938_363497_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGIALEGVRQQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVLQLLSGYQGKEPAETGGRGEGTPSSSLVLDQFGRNLTSSAREGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQNIVKGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDEIHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKHVEKDPALERRFQPIQVGEPTMEQTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIADVRRDKESAIDAQDFERAARLRDEEKQLLGQKAEREKQWKSGDLDVVAEVDDEQIAEVLANWTGIPVFKLTEEETTRLLRMEEELHKRIIGQEDAVKAVSQAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGEDDALIQIDMGEFHDRYTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEVYNTLLQVLEDGRLTDGQGRTVDFKNTVIIFTSNLGTQDISKAVGLGFAGGGTEGSNYDRMKQKVNDELKKHFRPEFLNRIDDIIVFHQLTEDEIIRMVDLMIARVETQLKNKDMSLELTANAKKLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFGELEAGHIIIGDVEGFEEGKSDDKARFVFRGEPKPSQVPDVPPVELSSSTGGNQELPPAEGESE
>NZ_CP014859.1|WP_084643524.1|359625_360495_-|(2Fe-2S)-binding-protein
MTTAFRRSGAYGSGTAANIAESIARLDLPPWLEARHGDAALDAGWSRCSSLLDDPASFTRWRELLSGWLIENYGAAPERTTAGYVMSWYLSVPGYLGALLFHTARRVPSLAPEHTAFRLAEGRPHLDGIALTGEAFACLPDDPAAHTSAATVVADEHALADLLRARFAGHAARFVAAFAPGTRLGRRMLWAAATDVLDTTLWLAGQMCGDEDGGVADAALVLGTAADPLLDPFTSVSTMYRVSVDDGERWTRRRGSCCFHYALPGSPQACTTCPRVGTAERDARVRELG
>NZ_CP014859.1|WP_069846060.1|358945_359296_+|Lsr2-family-protein
MAQKVTVTLVDDLDGSKADETVEFTFDGAAYQIDLSSANAGVLRDALAGFVGHARRSGGRKRNVRPGGDRADGGSTSAGDREQNQAIREWARKRGMKVSDRGRIPADVIDAYHAAN
>NZ_CP014859.1|WP_069853174.1|357334_358789_+|lysine--tRNA-ligase
MKVRREKRSRLLESGIEPYPVVLPITHTVAAIRAKHTDLEPDTATGEIVGISGRVMFLRNTGKLCFATLRSGDGSELQAMLSLAQIGAESLASWKADVDLGDHVFVHGEVITSRRGELSVMADEWRIAAKALRPLPVTHKELSEETRVRQRYVDLIVRPQARRIVETRAAVVRSLRESFHRHGFTEVETPMLQTLYGGAAARPFHTHSNAFDIDLYLRIAPELYLKRCVVGGMERVFEINRNFRNEGSDSSHSPEFAMTEFYQAYSDYNDIATLTRELIQEAARAACGGEVVTLIDGTEYDLSGEWKWLSMYGSLAEKVGEEVTPDTSVERLRAIAAEQGLEHDPALGHGKLIEELWEHLIGDHLYEPTFVKDFPIETSPLTRQHRTEPGVAEKWDLYIRGFELATGYSELVDPVVERERLEAQARLAAGGDVEAMRLDEDFLRALEYGMPPTGGCGMGVDRLLMALTGAGIRETILFPLVRPE
>NZ_CP014859.1|WP_069846059.1|356388_357174_+|type-III-pantothenate-kinase
MLLTIDVGNTNIVFGLYVGSGPDARLLRDWRMRTDARMTADELAWTMRGLLGEHADRITGISALSTVPAVARELRVMLARYYAEVPTLIVAPGVRTGVPLLVDNPKEVGGDRVVNTLAAHHLYDTACVVVDFGTSTNIDVISRKGEFLGGVFAPGIEISVDALAARAAQLRKVELLRPRNVIGKNTVECLQSGILFGFAGQVDGLVRRILAELSAGEHGPVTVLATGGLAPLVIGESETITTHVPDLTLIGLRLVYERNMS
>NZ_CP014859.1|WP_069846057.1|355816_356347_+|aspartate-1-decarboxylase
MLRTMLKSKIHRATVTQADLHYVGSVTVDEDLMDAADLLAGEQVAIVDVTNGARLETYVIPGERGTGVLGINGAAAHLVHPGDLVILIAYGLMDAAEIREHRPSVVFVDADNKVISLDADPAVVPDGFGLSSGSIDSRSADSAPTAGGSTTARSESIAAGETDDAVRLDALLQSER
>NZ_CP014859.1|WP_069846056.1|354819_355803_+|pantoate--beta-alanine-ligase
MTETQATPGAPGESPLFAPGDTTVHSDPAQLARVTRALRATGRRIVLVPTMGALHRGHRELIRRAKRVPNTIVVVSIFVNPRQFGAGEDFERYPRDLDTDVAVCRAEQVELVFAPTAAAMYGAGTSITVSAGPLGDELEGASRPGHFAGVLTVVAKLLNIVRPDFAFFGEKDYQQLVLLRRMGRELDFDASIVGIPTIREHDGLALSSRNVYLDAEARNAAVVLSAALTAGVYAARSGGDAARVLATAREVLDGEPALDVDYLELRDVELNAVDEQREARLLVAARVGAVRLIDNVAIAFGTAEEQPGEVADAPAADGAATDSAESR
>NZ_CP014859.1|WP_069846054.1|353905_354823_+|DUF2520-domain-containing-protein
MIDNAGVRPARLAVGVISAGRVGAVLGASLARAGHVVVATSAVSDASLRRAEQLLPDVPVLAPDEVATRADLVMLAVPDDVLPGMVAGLVATGALRAGQIVAHTSGAHGVDVLTPAAELGALPLALHPVMTFTGRSEDLERLAACCIGVTASGDPNSPVEPGWNVGEALVVEIGAEPVRIPEAVRPLYHAALAHGANHLITLLTECVGLLSQAGVAHPERLLGPLCGAAMDNALRHGDRALTGPVARGDLSTLRTHLDVLGEVAPEVVPSYRVLAARTADRARAAGLLSDSTAAEVDDLLNEEPR
>NZ_CP014859.1|WP_084643523.1|352242_353757_+|PrsW-family-intramembrane-metalloprotease
MTSSQASRWQRFLLPVLGVVILGLCGLTLLGLTHARVGAVALVVGAAAALLPLGPVIATFLWVDRWEPEPPRLLFAAFLWGACGATIAALLINDTAQVVGEVLLGTGGGDLVAALISAPLFEEAAKGLFVLAVLLRRRQEFNGIVDGIVYAGITGVGFAFTENITYFGLAFVQGGFGDMSGGVVAVFVLRGVLSPFTHSLFGAMLGIGLGIAACTSRPRMRIAAPLIGYLMAVLLHALWNGAATLGGGRIFINVYFLVMVPIFLSTALLVCWQRRREQHVVVTQLPGFAAEGWIAASEIGLLASLTSRKEWRVAVRKRSGASAGKAVAAYQLAVTELAFVRNQLAGGRTFPETAERLDQAVARLIRSRAAVLRSPGALADAARSTAGIRRRNRPSRGSGWLFDRQPVLLRALGPPRRPVSTEVTLPGIVVGSNRSADETLPIPKMVLEPLSSGAPTVRHDGVVAPVEPALTSAREPVIPAQSSESTDVTVVIDPVPPTSGEPKA
>NZ_CP014859.1|WP_157420894.1|365688_366552_-|NAD-dependent-protein-deacetylase
MSTDPIREAADLIADAEALLICAGAGFGVDSGLPDFRGPEGFWRAYPAYRSLGLDFAELADPVHFAADPALAWGFYGHRLDLYRRTTPHAGFGTLHRWGTALPGGFRVFTSNVDGQFQRAGFAEETIVERHGSIHRLQCTGPCAQRQWPADEVQVDLDEETMRARGPLPSCPDCGGLARPNILMFGDHSWVADHTSTAMDGLTTWLRPLRTARLVVIELGAGTAVPTVRRQAELASAARGALIRINLREPAIRHGRGIEIPMGAAAAIAAIDELLPDRLRAAVETAG
>NZ_CP014859.1|WP_069846064.1|366548_366860_-|antibiotic-biosynthesis-monooxygenase
MAVVKINAIEVPEGSGPELEKRFAARQGAVENAPGFLAFELLRPVAGENRYFVYTRWESEEAFQAWSGGPAKEAHSGERSKPVASGASLLEFEVIQHAESKGE
>NZ_CP014859.1|WP_172803890.1|366948_367467_-|2'-5'-RNA-ligase-family-protein
MTLDFFFDDASDRTIRDLWQRLADIGARPVPGSTHPAPHVRFAAAAEIAPRVRQDLRAELRALSLPSFWLTTLGTFATSAPVLMLGAVVDAELLAVHSTVHDVLAGRVKQPSAYYLPGSWVPHCPLAEGVEREALAAGFAELHPVRAIHARVVGVGVVDGRTGHTEDLVRLG
>NZ_CP014859.1|WP_069846067.1|367529_368414_-|A/G-specific-adenine-glycosylase
MKSTVLAPTTLIAWFDRTGRDLPWRHPETTGWGVLVSEIMLQQTPVVRVQPIWQDWMQRWPKPSSLAEATAADVLRAWGKLGYPRRALRLHAAAAAIAKNHGDVVPSDVDTLLALPGIGAYTARAVAAFAYGRRAPVVDTNVRRVVARAVHGSAEAGPPSTTRDLADVDTLLPEEDARAARYSAALMELGALVCTARNPTCVDCPVRVDCAWQQAGKPAYAGPTRPTQRFAGTDRQVRGLLLDVLRGASGPVERAKLDLVWQHDGQRDRCLDSLLVDGLAEQTEDGLFALPGES
>NZ_CP014859.1|WP_069846069.1|368740_370900_+|trypsin-like-serine-protease
MKQARLVASVLAAGVLAAGSIFGATPRGIAQQSDMSDLSAADQAANYPASLEVAIERDLATDPITYASNSLAAADASATADALRDQLADNFGGAWFDPAAGRLNVAVTSQGAADMVRQRGAEAHIRGVNEERLIEVSADLRAWIDGLPAERRALIYGLSTSAKTSSVTLAFSATSAGRSLAAELPGDHGVELNTEFVLEPPQTQQAADLLGGQGISAAAEDGSELASCSLGFNAIDGQGRALALTSGHCATDAATILAADGTEIGVPERVAWNSIADGDDGDDYASVRVQNPNLIAQPAVTDWQGGTLPVEGVVAPIEGMQVCHSGQTSQWECGQIQQVDVEVRVNGPDGTVKSQRSFWYDACTERGDSGGAVLAGTLAVGLHSAGALTPDDRRCLSTIGEQNIAFAEPLATDVIGDFGDDLRVLTTTADTDGDGVPDHEELAADRTTVHDANGDGVPAFLDPDEPTLGVPVVTSPEDGSRHTERSLPIVGTSKPGATVTVTYRGQSHLVTADDRGEWRLPAEEQLALGHYEITVSQSWTATNGSQWQSGETTSGFFIAPGPPAITSPQDGAEIDETAPMIFGTGEPGAVVELTVDDVDLGTASVVDDNGEWSITLVEPLSHGSHTIAAVQLVEDVGSNPTSITITVLPSEGGHTTVIPEAPGGPGANPPTGGDPDLADTGVSVALLALLGTAGLVAGTLLMLRRRREQLGVAGQTEAD
>NZ_CP014859.1|WP_069846071.1|370921_372304_-|DNA-repair-protein-RadA
MAPTKSAKPARPRYRCGECGLEVPKWVGRCPECQAWGSIDETAAPSRSSLSRVAAGAPATPARPIADVDVEAARARPTGVPELDRVLGGGIVPGAVVLLAGEPGVGKSTLLLEVAHQWAAGPGGPALYITGEESAGQVRLRAERTGNVHESLYVSAESDLSAVLGHVDAVRPGLLILDSVQTVQSPEVEGSPGGVTQVRAVTVALTALAKERGLPVVLVGHVTKDGSVAGPRVLEHLVDVVLHFEGDRHSTLRMVRGVKNRFGPADEVGCFELADDGIVGLADPSGLFLNRRETAVAGTAVTVVVEGKRPLLAEVQALVSKSTLAMPRRAVSGLDSARVSMILAVLERRGRVRLGESDVFTATVGGMKVNEPASDLAVALAVASAANDRPLPPDLAVVGEVGLAGEIRRVAGAGRRFAEAARLGFTRALVPPDSGPLPPELRAVVVPDLRAALAELRRGD
>NZ_CP014859.1|WP_157420896.1|372446_373217_-|hypothetical-protein
MRRAEQTVRRGIGTGSARRRLVPVALAAGIALIAGGCSAGQITQTSRKEPIIDGINGDVGDMAIRDAQLLFPVGEDPRYEAGDSVPLSVTLVNTGSVTDTLVEITSPSAQVVQVQGDTVIPGGTSIVATVDPRDWTDAQRQLAEQQESADASGTPGDTEDEDGENQDSEDAENQDGDQDNTTGDETSPSDQPESSANRQPLEDNVITVVLDELVNDVQAGTNLEVVFVFENAGQISLQVPLGPPAEGRPVEQNDEH
>NZ_CP014859.1|WP_069846075.1|373504_373993_+|CarD-family-transcriptional-regulator
MVFKVGETVVYPHHGAALIEAIETRVIKGEEKKYLVLKVAQGDLTVRVPADNAEIVGVRDVVGQEGLNRVFEVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRREKDRGLSAGEKRMLAKARQILVSELALAEGTDEGKAEILLDEVLETAS
>NZ_CP014859.1|WP_069846077.1|374031_374784_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MSVIAVVPAAGRGERLGAQVPKALVEVAGEPLLVHAVHGLLSAGCVDHVVVAAPAAEVSVVVAAVERFGSQVSVVVGGAERGDSVRLALRSGLTVLPGARVVLVHDAARAFTPVEVIRSVVDAVRSGLPAVIPVLPVADTVKQIDSTGRVVATPDRAGLRLVQTPQGFDVDVLRKAYGLDSDPDGASPMSILNTDDAGLVEQSGIPVHIVAGHSHAFKVTTPFDLAVVDAMLAQKAVAAERADETVGEAR
>NZ_CP014859.1|WP_069846079.1|374780_375278_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MTELSALAVPRVGLGTDVHPIQEGKDCWLAGLHWPDATGCAGHSDGDVAAHALCDAMLGAVALGDLGSVFGTSAPEWAGAHGVALLGEVRRRFEAAGYRLGNAVVQIIGNAPRIGPRREEAQRVLSEAAGGPVSVTATTTDGLGLTGRGEGVAAIATALLVPVQG

Crispr_ID: NZ_CP014859_3

• CRISPR_ID: NZ_CP014859_3
• CRISPR_location: 1157482-1157766
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014859_3

Consensus_repeat	Method
GGCTCCAACGCGTGGGTGGAGTGGGACGGCGCCCCGCCGATCGACTCCGACTTCAG	PILER-CR
GACTTCAGCAACGGCGGTGGCGACCGACCGGGTGGCGG	CRISPRCasFinder

spacers of NZ_CP014859_3

>3.1|1157538|61|NZ_CP014859|PILER-CR
TGTCACCTCGCTGGTAGGACCCGACAGCTCGAGTGGCAACCAGTCGGGTGGTGGATCCGGT
>3.2|1157655|37|NZ_CP014859|PILER-CR
CAACGGCGGTGGCGACCGACCGGGTGGCGGGTCCAAC
>3.3|1157674|55|NZ_CP014859|CRISPRCasFinder
GTCCAACGGCTCCAACTCGTGGGTGGAGTGGGACGGCGCCCCGCCGATCGATTCC

CRISPR arrays and Neighbor proteins around NZ_CP014859_3

CRISPR arrays

The CRISPR arrays of NZ_CP014859_3

>merge|NZ_CP014859|3|1157482-1157766|PILER-CR,CRISPRCasFinder
CAACGCGTGGACCGAGTGGGACGGGGCCCCGCCGTTGGACACCGATGTCACCTCGCTGGTAGGACCCGACAGCTCGAGTGGCAACCAGTCGGGTGGTGGATCCGGTGGCTCCAACGCATGGGTGGAGTGGGACGGCGCCCCGCCGATCGACTCGGACTTCAGCAACGGCGGTGGCGACCGACCGGGTGGCGGGTCCAACGGCTCCAACTCGTGGGTGGAGTGGGACGGCGCCCCGCCGATCGATTCCGACTTCAGCAACGGCGGTGGCGACCGATCGGGTGGCGG

>NZ_CP014859|3|2|1157482-1157736|PILER-CR
CAACGCGTGGACCGAGTGGGACGGGGCCCCGCCGTTGGACACCGATGTCACCTCGC	TGGTAGGACCCGACAGCTCGAGTGGCAACCAGTCGGGTGGTGGATCCGGTGGCTCCAACGC
ATGGGTGGAGTGGGACGGCGCCCCGCCGATCGACTCGGACTTCAGCAACGGCGGTG	GCGACCGACCGGGTGGCGGGTCCAACGGCTCCAACTC
GTGGGTGGAGTGGGACGGCGCCCCGCCGATCGATTCCGACTTCAG

>NZ_CP014859|3|3|1157636-1157766|CRISPRCasFinder
GACTTCAGCAACGGCGGTGGCGACCGACCGGGTGGCGG	GTCCAACGGCTCCAACTCGTGGGTGGAGTGGGACGGCGCCCCGCCGATCGATTCC
GACTTCAGCAACGGCGGTGGCGACCGATCGGGTGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069847056.1|1162388_1164281_+|S9-family-peptidase	unknown	unknown	gnl|CDD|224423
NZ_CP014859.1|WP_069847046.1|1155705_1156221_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|376829
NZ_CP014859.1|WP_069847039.1|1149905_1151435_-|MFS-transporter	unknown	unknown	gnl|CDD|184957
NZ_CP014859.1|WP_069847047.1|1156220_1156544_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847061.1|1166666_1167551_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP014859.1|WP_069847051.1|1158248_1159682_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|365919
NZ_CP014859.1|WP_069847059.1|1165896_1166619_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NZ_CP014859.1|WP_157421359.1|1167941_1169099_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP014859.1|WP_069847037.1|1149291_1149867_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
NZ_CP014859.1|WP_069847053.1|1159678_1161223_-|GMC-family-oxidoreductase-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|225186
NZ_CP014859.1|WP_069847055.1|1161344_1162106_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133381
NZ_CP014859.1|WP_069853313.1|1151527_1152391_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375319
NZ_CP014859.1|WP_069847044.1|1154226_1155249_-|zinc-dependent-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|176247
NZ_CP014859.1|WP_069847058.1|1164759_1165443_-|DUF3159-domain-containing-protein	unknown	unknown	gnl|CDD|371490
NZ_CP014859.1|WP_069847063.1|1167714_1167939_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847042.1|1153788_1154190_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380361
NZ_CP014859.1|WP_069853312.1|1147555_1149172_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP014859.1|WP_069847041.1|1152537_1153587_-|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176186
NZ_CP014859.1|WP_069847065.1|1169095_1169698_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014859.1|WP_084643566.1|1145806_1147123_-|endo-1,4-beta-xylanase	unknown	unknown	gnl|CDD|366032

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069847056.1|1162388_1164281_+|S9-family-peptidase	gnl|CDD|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	4.12952e-85
NZ_CP014859.1|WP_069847046.1|1155705_1156221_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	1.04508e-11
NZ_CP014859.1|WP_069847039.1|1149905_1151435_-|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	7.50776e-67
NZ_CP014859.1|WP_084643566.1|1145806_1147123_-|endo-1,4-beta-xylanase	gnl|CDD|366032	pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10.	3.12535e-145
NZ_CP014859.1|WP_069847061.1|1166666_1167551_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.81397e-80
NZ_CP014859.1|WP_069847051.1|1158248_1159682_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|365919	pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3. Succinate-semialdehyde dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2.1.28. Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27. Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9. Delta-1-pyrroline-5-carboxylate dehydrogenase EC: 1.5.1.12. Acetaldehyde dehydrogenase EC:1.2.1.10. Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This family also includes omega crystallin, an eye lens protein from squid and octopus that has little aldehyde dehydrogenase activity.	1.12577e-108
NZ_CP014859.1|WP_069847059.1|1165896_1166619_-|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	0.00206412
NZ_CP014859.1|WP_157421359.1|1167941_1169099_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	7.20393e-24
NZ_CP014859.1|WP_069847037.1|1149291_1149867_-|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	5.81347e-17
NZ_CP014859.1|WP_069847053.1|1159678_1161223_-|GMC-family-oxidoreductase-N-terminal-domain-containing-protein	gnl|CDD|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	2.07682e-99
NZ_CP014859.1|WP_069847055.1|1161344_1162106_-|MerR-family-transcriptional-regulator	gnl|CDD|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	2.56474e-18
NZ_CP014859.1|WP_069853313.1|1151527_1152391_-|helix-turn-helix-domain-containing-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	6.31215e-50
NZ_CP014859.1|WP_069847044.1|1154226_1155249_-|zinc-dependent-alcohol-dehydrogenase-family-protein	gnl|CDD|176247	cd08287, FDH_like_ADH3, formaldehyde dehydrogenase (FDH)-like. This group contains proteins identified as alcohol dehydrogenases and glutathione-dependant formaldehyde dehydrogenases (FDH) of the zinc-dependent/medium chain alcohol dehydrogenase family. The MDR family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. FDH converts formaldehyde and NAD to formate and NADH. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	0
NZ_CP014859.1|WP_069847058.1|1164759_1165443_-|DUF3159-domain-containing-protein	gnl|CDD|371490	pfam11361, DUF3159, Protein of unknown function (DUF3159). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed. Currently this family of proteins has no known function.	1.30003e-56
NZ_CP014859.1|WP_069847042.1|1153788_1154190_-|cupin-domain-containing-protein	gnl|CDD|380361	cd02233, cupin_HNL-like, Granulicella tundricola hydroxynitrile lyase (GtHNL) and related proteins, cupin domain. This family includes archaeal, eukaryotic, and bacterial proteins homologous to hydroxynitrile lyase from Granulicella tundricola (GtHNL), a novel class of HNLs that does not show any sequence or structural similarity to any other HNL and does not contain conserved motifs typical of HNLs. HNLs comprise a diverse group of enzymes that vary in terms of their substrate specificity, enantioselectivity and the need for a co-factor. In plants, they catalyze the reversible cleavage of cyanohydrins, yielding HCN and aldehydes or ketones. Also included in this family is TM1010 from Thermotoga maritima, a protein of unknown function. Some but not all members of this family have N- or C-terminal carboxymuconolactone decarboxylase domains in addition to the cupin domain. Members of this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.31476e-46
NZ_CP014859.1|WP_069853312.1|1147555_1149172_-|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	5.93555e-16
NZ_CP014859.1|WP_069847041.1|1152537_1153587_-|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP014859.1|WP_069847065.1|1169095_1169698_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.23226e-54

Protein sequences

>NZ_CP014859.1|WP_069847047.1|1156220_1156544_+|hypothetical-protein
MADGFESDPGALRTRSPKFVEAADRLTAAFETLQTVRDAEHGCWGADETGKNFEPDYITASEEADKGRDYLVEGLTATKDGLDKTADQWESDDETNADNIKSAGGGL
>NZ_CP014859.1|WP_069847046.1|1155705_1156221_+|YbaB/EbfC-family-nucleoid-associated-protein
MTNPSNQRLELEARNAAMREKMTSLLAGVSRQAEQLKQVQEHAASATGEATSRDGLVNVRVNSAGIVTDLQINPAAFRSTTAVKLSQAIVHTIQQAARNARAQADEVLAPMLADLPDMPDLFEGAPSFKDLTPKVPDIPDTGVVDDDDRGRSDDDDDEDDELASRWEERYR
>NZ_CP014859.1|WP_069847044.1|1154226_1155249_-|zinc-dependent-alcohol-dehydrogenase-family-protein
MRGAVIHAPGDVRFEERADPVIEAPTDAIIRLTATCVCGSDLWTYRGVDPITAPTPMGHEYIGVVEEVGSAVGTIRPGQFVVGSFFASDDTCEICRAGFHTSCVHRIPIGSIGSQAEYLRVPLADGTLVATHELPSADLLPSLLAASDVLGTGWYGAVAAEVRPGSTVVVVGDGAVGLLGVLAAKQLGAERIIAMSRHESRARLAREFGATDVVAERGDDGVQAVKDRTDGLGAHSVIEAVGTQESMMQAIRSARPGGAVGYVGVAHDVTLPGEELFYSHVRILGGPAPVRRFLPDLLDRIQAREIDPGKVFDLELPLGQVAEGYRAMDERRSIKALLWP
>NZ_CP014859.1|WP_069847042.1|1153788_1154190_-|cupin-domain-containing-protein
MRLIPVQDAAKAPETNFTGDVHLTPIKQAQPPSRLVVALVRFTPGARTNWHSHANGQTLHVTEGVGLVVNRDGQVIRMRAGDTVWTPPGEEHWHGGTDSTMLCHLAMVEGTGDGDGTTWLEAVTDEQYADAQF
>NZ_CP014859.1|WP_069847041.1|1152537_1153587_-|NAD(P)-dependent-alcohol-dehydrogenase
MSQARAYTATSATAPLEPGTIERRAVGPNDVRIDIVWAGICHSDIHTVRGDWGPVPYPLTVGHEIAGVVAAVGDQVTRYQVGDRVGVGCMVDSCRECSNCRAGFEQYCRKGMVDTYGGNDGNGGVTQGGYSSEIVVDENYVLRIPDSLPFEKTAPLLCAGITTFSPLRRWGAGPGKRVAVVGMGGLGHIAVKIAHAMGAEVTVLSQSLSKREDGLRFGADHYYATSDPATFEQLAGSFDLILNTVSASIDLDAYLELLALDGTIVSVGAPAEPVPVTLFTLFDNRRTFAGSKIGGIRETQEMLDFCAEHGIAAEVEVIPAEGINEAWERVLASQVRYRYVIDIATLANA
>NZ_CP014859.1|WP_069853313.1|1151527_1152391_-|helix-turn-helix-domain-containing-protein
MTRRARLRPAQVGLPDLGDARRVPGLRREEVAVLAGVSLDYYTRLERGNIAGASDSVLEAVAGALLLNQTERTHLFDLARAAASTSRRRKPTRSPHHVRGSVRRMIESMDTAAVVQNTRQDIVAANALGRALYAPMFDAEDEPNTARFAFLDPRAQSFYVDWAQVRRMTAAMLRMEAGRNPLDADLTRLIGELSTRSSEFRKDWAAHHVHVHETGKKIFCHPEVGEIEVEFDVFELVGDQGLRLATYGTEPGTPSADAFALLASLTMTDRQARTPSRSNIHASHEAD
>NZ_CP014859.1|WP_069847039.1|1149905_1151435_-|MFS-transporter
MSELVARRAGMREWAGLGLLALPTALLGLDVTVLYLVLPSMSEALTPSATQTLWIMDAYGFLIAGFLITMGTLGDRVGRRRLLMIGMAAFAAISIFAAFAPNAELLVLARALLGIAGATLMPSTLSLISNMFPDPRSRAVAIGVWATMFALGMAAGPVAGGMLVDRFWWGAAFLLAVPVAVIVLLGARTLLPEYTAPDAGRLDPGSVVLSLLAILPVVYAVKHTAADGPDLGAALLVVFGTAAGWLFVRRQRSLASPLLDVTLFADRAFSAALAVLLIGLVGVGGTMYLVTQYLQLGEGMSPLTAGLWMGPPALAMFAAAVGAPLIARRVPPGLVIAIALGLSVLGYAQLTFVDTGQASSVVLGFAFVYLGLGALAALGTDMVVGAAPATKSGSAAALSETVQELGVAIGVAILGSLTTAVYRARMVVPAEVEPEVADRITDSLSGALSVADQVPAAVLTDAAQVFTSGVNIASAVAGSAILAATVLCLVLLRQVRPISADHGGASSPH
>NZ_CP014859.1|WP_069847037.1|1149291_1149867_-|TetR-family-transcriptional-regulator
MQGDEKENVDGRKARGNRRRTEIIEATLAVVTRDGAAGVTHRTVAKQAGITTSLSTYYFATLDDLLVAALTSVVDIYTERIRQIIDDPGDRLRALAELIVESGGPGRERALVERELCTLAARRPALAPVARRWRSDMAELAATLTTDEEAIAELVAVADGLCTAILIDNIRADTDYVHALLLRALRPHDAA
>NZ_CP014859.1|WP_069853312.1|1147555_1149172_-|alpha/beta-hydrolase
MLSTRESRDSRTRSRVLRASGIAVALLVVGACTSANEEPESAQEATQEIGENAPALARFYDQDLEFGSCADYAANETEEMIYVDPFECARLEVPLDYAEPEGETAQVAVLRIAASGEDKIGSLVTNPGGPGGTGLTGVVVAFAGLKDTPLPEKFDFIGFDPRGVGASTPAIDCFTDEEHDRGEDMTTLLGVSGEWSEEDTRGLVERCAENSGGEDVLASVGTRNTAQDMDVLRAALGDDQLTFAGQSYGTRLGAVYGEMFPDKVRAMSLDGAADPTLGSAERRLTQQEGFQGAFDEMAAFCAEDAECPLGTDPEQATEAFQDIVQPLLDNPVSTDSGRELSYNRATGGVIAGLYTEQQWPRIIDGLAQVKNEGRGDELLALYEEFGGRSPDGKWINFSEANYAINCNDEERRSPEEEAELRAEVMSVSPFMQTGEPTEGVTRDACEFWPVEPSLGLPYAQDVEGLPETLVISITGDPSTPYGAAENLAESLGGTVLTVEGEQHTVAFSGANACVNEVFADYLIDLEIPAADKTCTLGE
>NZ_CP014859.1|WP_084643566.1|1145806_1147123_-|endo-1,4-beta-xylanase
MLVGMTTVSTTTHTASAADAPGAATTSDTAQLQQDTLAAAAERTGRYFGAAVAAHKLSDSTYVGILNREFNSVTAENEMKIDALEPQQGQFTYGNADRIVNHAIQQGKDVRGHTLAWHSQQPQWMQNMSGSALRQAMLHHVTQVASYYRGKIHSWDVVNEAFADGNSGARRDSNLQRTGDDWIEAAFRAARAADPNAKLCYNDYNTDNWQHAKTQAVYRMVQDFKSRGVPIDCVGFQAHFNSGNPVPNNYHTTLQNFADLGVDVQITELDIEGSGNSQAEQYRGVTQACLAVTRCTGITVWGIRDSDSWRASGTPLLFDDNGGKKAAYYGVMEALGGDGGTNPPEEPGPGDCTTTYTAGQQWNDRFNGEVRVSGTDNWIVTVTIGSRQQVINTWNATVSWDSSGRVMTARPNGNGNTFGLTILHGGDWAWPSLNCRTA
>NZ_CP014859.1|WP_069847051.1|1158248_1159682_-|aldehyde-dehydrogenase-family-protein
MSESDAGSIRELIGGTAGIPAGELTQVLTDPNTGAALYPQRATTPENVEKALATAWRVHTEGVWAELPRADRAAALRRLQAELTERVDELARADSLDNGTPTTFTAMFTGGVIGLLELAASQIEDGFGHTEQVSATAGVCDQWRLPWGPAAVFLPWNAPSSMAIMKTASALVAGAPIVIKPSEWAPHFSGAFAEAVQAALPEGVVQIVHGDRTVGQTIVADERIAAVSYTGGVQGGRAVAQTCARDFKPIDMELSGNNPVIALPDADPTSVAEQLAPGMVMLNGQFCIGPRRLIVPESQIEAYLEALAAVLSAVPIGATDDPAAQLGPLAHEQQRNRIEEQLEQFAALGCEVRRYGKLPGLTGHFFAPAVVLADQSADLKDEIFGPVIQVRTYRDVDEAVTIANDHAYGLSGYVFGADRDTARAVGKRLRSGVVTINSVLGAPADVPRVGSMWGISGLGEIGVGHGPNFFGGLRFVG
>NZ_CP014859.1|WP_069847053.1|1159678_1161223_-|GMC-family-oxidoreductase-N-terminal-domain-containing-protein
MYDTIIIGAGSAGAAVASRLTEDEHRRVLVLEAGLDYRSAETGPELQSVEPGKIKVAIEFAETHTFPKLLARRSAAQSALPYVRGKGVGGSSAINGLFAIRGDASDFDGWAAQGCTGWGYQDVLPLLNKLENDQDFPDAEYHGADGPIPIVRPKRENFATVETAVDQLTQRLGHPWAPDHNAPNSTGVSPYAYNSFGTKRVSTNDAYLEPARDRANLTVIGNALVDRVLFVGNRVVGVRAIVDGEPTDFHAGEVVLSAGAIHSPALLQRSGVGIASELRELGIEPIADLPVGRNLQDHPGIGLVLGMNEPPDFGDQPERGQLCLRFTTGIGDEVNDVMLATPGALGIGVPAAAILGWVNRMSGTGRVQLAGTDPTLDPTVDFDMLSHPDDLRRFRALVDELRTFAAQPELQKITVAMGLGSAMADPTESMSDSEFVEFALANVHDTVHAAGSCRMGSANDPATVVDPQGRVLGIEGLRVADASIFPWATRANTHLTSVLVGEKIADSMRNGSVA
>NZ_CP014859.1|WP_069847055.1|1161344_1162106_-|MerR-family-transcriptional-regulator
MAWSTRQIAELTNTTVKTIRHYHKVELLAEPERGSNGYKRYTVAHLTQVLRIKRLAELGFSLAQIGEMGDTDEHLGQALRVLDAELAETIDRLQRVRAELAVLLHNAGPTDLPLELGGFIATKKLPEADRSLTVVVSRVLGPAALDAYQEILREHCDEALSTAFEQLHADTDESTRRELAARLVEHIQALDAEHPGLLRPIVGAGNDAQFTSNTIRLAINDLYHPAQTDVLDRVQRGLRSAVIAQQGNSPLVG
>NZ_CP014859.1|WP_069847056.1|1162388_1164281_+|S9-family-peptidase
MALPDIIPVEELFNPPGKLGASISPDGTLLAYLAPWKNRLNVWVQSLDSDTEARCVTADETRSVTNFQWAGDQRWLLYFQDTGGDENHHVFRVDLTDSAAPAVDLTPFPKARVVGFEQPPGRPGKALLQLNNRDVAEFDLLELDIASGELTVLAENPGHVTSWLHTPDGELFARTLSADGDIVVSRWKGADGQPEPIAVFDGIDYPLDVAPFELAADGTGVWIGSSRDRDLTRLARLDLTTGEETEVDSHPTLELDGVRRAVLQTTSPLIRSRGTGELLGVRYLGERQVIQAVDPDFAVILERLTALSEGDLGEMSSDRSGQRWVVSFLHDRQPGATWFYDHATGRSRLLFTAYPNLDPETLAPMVPVTITARDGRPLPSYLTLPVGIEPVGLPLVLLPHGGPWARDFWNFKANVQLLANRGYAVLQVNFRGSVGYGKAHMQAAIGEFAGAMHHDLVDAVEWAVARGYADPKRLGIFGGSYGGYATLVGVTFTPDLFAAAIDYVGISNLATFMQTLPSFVKYQLINNWFRYVGDPDDPEQYADMLARSPISRVDQIRTPLMVVQGANDVRVVKAESDNIVEALRARGVDVEYLVKNNEGHGFVNPENQIDMFRRVERFLAQHLGGRQAEG
>NZ_CP014859.1|WP_069847058.1|1164759_1165443_-|DUF3159-domain-containing-protein
MRPEQDATEVHPTIAPTEAPPATPTLLEQSGGVSGAIYAGIPVVVFVVANSAWGLTMAIWLSVGAAVLITLVQLLRKVPFSQASSGLIGVGICVLLAQLTGSADGFFLFGIWSSLVFAVVSLLTMVLRWPLAGVIGGLTNGKGNVWREDKPSMRAYNIATLALVAMFASRFVVQQWLFVEESTGWLAVADIVMGFPLLAVAGLVVVWAVRFSTKRLKALEEQPVQNG
>NZ_CP014859.1|WP_069847059.1|1165896_1166619_-|ABC-transporter-permease
MLSIARSELVQLFRNKAVLLTMFIIPVAMAGFFIYQHELFESLGGGLGAIAAIMIFYVAGLGLYTTAVTTLASRRQNLFLKRLRSTAASDSTILFGLMLPVVVISVLQSVVILGVLGVVAGAPGDILMLVLAVLSLFVMMVGLALATAGITNSPEHAQVTTLPIGVGTVALASWIGFAGGGDLQILQRVLPGGSAAELIVESWNGGISLSDSLPLLIPTAAWIVVSVVLAIRYFRWEPRR
>NZ_CP014859.1|WP_069847061.1|1166666_1167551_-|ABC-transporter-ATP-binding-protein
MTSTPVIDVERLNLKYGDFHAVKDLSFQVSRGELYALLGTNGAGKTSTLEIIEGHRKPTSGTVRVFGQSPRDRVAVRPKMGVMLQESGFSPDLTVKESVALIGKLTQRTDTVDRVLSIVDLTRKASTQVSQLSGGEKRRLDFATAVYGTPELIFLDEPTTGLDIQSRDDLWEAVDKLREDGSTIVLTTHYLEEAQQRADRIGLMHRGSFHQEGTVSELTQTLPAVISFFLPPHTPALPLPAERESDGRFLIKTTDRQRDLYVLLRWALENSVQLRDLEAGPTRLDDVFRSIGSD
>NZ_CP014859.1|WP_069847063.1|1167714_1167939_+|hypothetical-protein
MNTRPLRILLTVLTTVFVLVCVLFFLNRVGTGLLPDGLGSWLGGNEWAMWTSAAVAVISGLGVSLLSLNERDED
>NZ_CP014859.1|WP_157421359.1|1167941_1169099_+|sensor-histidine-kinase
MALPKDEQENPSSTRGRLRRLNVISVLAALGPAGILLVAVESQTWVHAAILSAGVAAGLLAAQRWAMGDLERFAVPCLVVTLSVWVAGAFIADAPSASYGTTILAPLVISALPRHRVIATVGFVAFAGLIGLGRLLVTEGDTVRIVVFFAFLPAVIISITTGLMAANRAFMALFEEVEQAREREGEVAVARERARFASDLHDIQGHTLHVVKLKVALAEKLVRVDVDRAAEELREVHALVGDTIKQTKELAYAQRQLNLSAELENAKNLFEAAGIRVRVTRQAEVDPGVSQLLGQVLRETTTNILRHAEAKQVRITLSAGGIVIVNDGAPDEPLPNLRGLATLRERLAGSGGELDVQQQDGSFHTIARFPNLRRTAETEAGKNSR
>NZ_CP014859.1|WP_069847065.1|1169095_1169698_+|response-regulator-transcription-factor
MTTVVLADDEVLLRKAMAALLPLEAEITVLAEAEDGAQAVTATLEHRPDVLVIDLEMPNVDGLGAVAEIRRDRPEQVILMLTRHAKPGVLRKALKLGVQGFVSKSAEPAHIASVIKALHAGKRWIDPDVSALAVVDDCPLTEREIDVLRATSEGYSAADIAKQLHLALGTVRNYLSNAMQKTQTRTRHEAARYARSHNWL

Crispr_ID: NZ_CP014859_4

• CRISPR_ID: NZ_CP014859_4
• CRISPR_location: 1200685-1201381
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of NZ_CP014859_4

Consensus_repeat	Method
GTTGCGATCCTCAGCGGGCCCGGAGGCCCGCTGCCAC	PILER-CR
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACT	CRISPRCasFinder
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	CRT

spacers of NZ_CP014859_4

>4.1|1200722|35|NZ_CP014859|PILER-CR,CRT
ACCGACGAGGTCTTGGCTACGCCGTTGGCGGCACG
>4.2|1200794|37|NZ_CP014859|PILER-CR,CRT
TGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
>4.3|1200868|37|NZ_CP014859|PILER-CR,CRT
TTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
>4.4|1200942|37|NZ_CP014859|PILER-CR,CRT
TGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
>4.5|1201016|37|NZ_CP014859|PILER-CR,CRT
TTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
>4.6|1201090|37|NZ_CP014859|PILER-CR,CRT
TCCCTCTCGTTGGTGATCGGCGGGTCGGGTGGTGGGT
>4.7|1201164|35|NZ_CP014859|PILER-CR,CRT
CGCTACCGGGGTGTCGTGCGGCGCCTCTAGGGCGT
>4.8|1201236|35|NZ_CP014859|PILER-CR,CRT
GACCCTGTCTGGTCGATCACCTCGGCGGACGGAAG
>4.9|1201308|36|NZ_CP014859|PILER-CR,CRT
CTCGTCGCGACCGCGTTCGCCGGAGTCGCGATGCTC
>4.10|1200723|34|NZ_CP014859|CRISPRCasFinder
CCGACGAGGTCTTGGCTACGCCGTTGGCGGCACG
>4.11|1200795|36|NZ_CP014859|CRISPRCasFinder
GTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
>4.12|1200869|36|NZ_CP014859|CRISPRCasFinder
TCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
>4.13|1200943|36|NZ_CP014859|CRISPRCasFinder
GTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
>4.14|1201017|36|NZ_CP014859|CRISPRCasFinder
TCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
>4.15|1201091|36|NZ_CP014859|CRISPRCasFinder
CCCTCTCGTTGGTGATCGGCGGGTCGGGTGGTGGGT
>4.16|1201165|34|NZ_CP014859|CRISPRCasFinder
GCTACCGGGGTGTCGTGCGGCGCCTCTAGGGCGT
>4.17|1201237|34|NZ_CP014859|CRISPRCasFinder
ACCCTGTCTGGTCGATCACCTCGGCGGACGGAAG
>4.18|1201309|35|NZ_CP014859|CRISPRCasFinder
TCGTCGCGACCGCGTTCGCCGGAGTCGCGATGCTC

CRISPR arrays and Neighbor proteins around NZ_CP014859_4

CRISPR arrays

The CRISPR arrays of NZ_CP014859_4

>merge|NZ_CP014859|4|1200685-1201381|PILER-CR,CRISPRCasFinder,CRT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACACCGACGAGGTCTTGGCTACGCCGTTGGCGGCACGGTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACTGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCAGTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACTTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGCGTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACTGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCAGTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACTTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGCGTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACTCCCTCTCGTTGGTGATCGGCGGGTCGGGTGGTGGGTGTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACCGCTACCGGGGTGTCGTGCGGCGCCTCTAGGGCGTGTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACGACCCTGTCTGGTCGATCACCTCGGCGGACGGAAGGTGGCAGTGGGCCTCCGGGCCCGCTGAGGATCGCAACCTCGTCGCGACCGCGTTCGCCGGAGTCGCGATGCTCGTGGCAGCGGGCCTCCGGGCCCGTCGAGGATCGCAACC

>NZ_CP014859|4|3|1200685-1201380|PILER-CR
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	ACCGACGAGGTCTTGGCTACGCCGTTGGCGGCACG
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TCCCTCTCGTTGGTGATCGGCGGGTCGGGTGGTGGGT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	CGCTACCGGGGTGTCGTGCGGCGCCTCTAGGGCGT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	GACCCTGTCTGGTCGATCACCTCGGCGGACGGAAG
GTGGCAGTGGGCCTCCGGGCCCGCTGAGGATCGCAAC	CTCGTCGCGACCGCGTTCGCCGGAGTCGCGATGCTC
GTGGCAGCGGGCCTCCGGGCCCGTCGAGGATCGCAAC

>NZ_CP014859|4|4|1200685-1201381|CRISPRCasFinder
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACA	CCGACGAGGTCTTGGCTACGCCGTTGGCGGCACG
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACT	GTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACT	TCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACT	GTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACT	TCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACT	CCCTCTCGTTGGTGATCGGCGGGTCGGGTGGTGGGT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACC	GCTACCGGGGTGTCGTGCGGCGCCTCTAGGGCGT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAACG	ACCCTGTCTGGTCGATCACCTCGGCGGACGGAAG
GTGGCAGTGGGCCTCCGGGCCCGCTGAGGATCGCAACC	TCGTCGCGACCGCGTTCGCCGGAGTCGCGATGCTC
GTGGCAGCGGGCCTCCGGGCCCGTCGAGGATCGCAACC

>NZ_CP014859|4|2|1200685-1201380|CRT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	ACCGACGAGGTCTTGGCTACGCCGTTGGCGGCACG
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TGTTCGCGCGTCCGCACCTGCACCCGCACCCGCGCCA
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TTCCTCGACCGAGGTCACGCCCGGTTGGGTCATGAGC
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	TCCCTCTCGTTGGTGATCGGCGGGTCGGGTGGTGGGT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	CGCTACCGGGGTGTCGTGCGGCGCCTCTAGGGCGT
GTGGCAGCGGGCCTCCGGGCCCGCTGAGGATCGCAAC	GACCCTGTCTGGTCGATCACCTCGGCGGACGGAAG
GTGGCAGTGGGCCTCCGGGCCCGCTGAGGATCGCAAC	CTCGTCGCGACCGCGTTCGCCGGAGTCGCGATGCTC
GTGGCAGCGGGCCTCCGGGCCCGTCGAGGATCGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069847093.1|1188755_1189862_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|274056
NZ_CP014859.1|WP_069847106.1|1199773_1200460_-|YdcF-family-protein	unknown	unknown	gnl|CDD|99750
NZ_CP014859.1|WP_084642589.1|1202043_1202919_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|372434
NZ_CP014859.1|WP_069847113.1|1207840_1210141_+|3-oxoacyl-ACP-synthase	unknown	unknown	gnl|CDD|238430
NZ_CP014859.1|WP_069853322.1|1205136_1205886_+|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl|CDD|273824
NZ_CP014859.1|WP_069847104.1|1198188_1199763_+|AfsR/SARP-family-transcriptional-regulator	unknown	unknown	gnl|CDD|276938
NZ_CP014859.1|WP_069847102.1|1195400_1196510_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl|CDD|99740
NZ_CP014859.1|WP_157420964.1|1201387_1201834_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069853319.1|1196995_1198189_+|glycosyl-transferase	unknown	unknown	gnl|CDD|273616
NZ_CP014859.1|WP_069847095.1|1189833_1190391_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847115.1|1210137_1210869_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380311
NZ_CP014859.1|WP_069853318.1|1190699_1191686_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP014859.1|WP_069847109.1|1205921_1206224_+|hypothetical-protein	unknown	unknown	gnl|CDD|181682
NZ_CP014859.1|WP_069853321.1|1203217_1204831_-|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|235704
NZ_CP014859.1|WP_069847099.1|1193277_1193883_+|dTDP-4-dehydrorhamnose-3,5-epimerase-family-protein	unknown	unknown	gnl|CDD|380337
NZ_CP014859.1|WP_084642591.1|1206220_1206745_+|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl|CDD|234568
NZ_CP014859.1|WP_069847100.1|1193971_1195435_+|NDP-hexose-2,3-dehydratase-family-protein	unknown	unknown	gnl|CDD|367562
NZ_CP014859.1|WP_069847111.1|1206748_1207813_+|glycine-cleavage-system-protein-T	unknown	unknown	gnl|CDD|234742
NZ_CP014859.1|WP_069847097.1|1191783_1192614_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|281995
NZ_CP014859.1|WP_069853324.1|1210865_1212107_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223717

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069847093.1|1188755_1189862_-|HAD-IA-family-hydrolase	gnl|CDD|274056	TIGR02252, Rhythmically_expressed_gene_2_protein, REG-2-like, HAD superfamily (subfamily IA) hydrolase. This family of proteins includes uncharacterized sequences from eukaryotes, cyanobacteria and Leptospira as well as the DREG-2 protein from Drosophila melanogaster which has been identified as a rhythmically (diurnally) regulated gene. This family is a member of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The superfamily is defined by the presence of three short catalytic motifs. The subfamilies are defined based on the location and the observed or predicted fold of a so-called 'capping domain', or the absence of such a domain. This family is a member of subfamily 1A in which the cap domain consists of a predicted alpha helical bundle found in between the first and second catalytic motifs. A distinctive feature of this family is a conserved tandem pair of tryptophan residues in the cap domain. The most divergent sequences included within the scope of this model are from plants and have "FW" at this position instead. Most likely, these sequences, like the vast majority of HAD sequences, represent phosphatase enzymes.	3.59619e-15
NZ_CP014859.1|WP_069847106.1|1199773_1200460_-|YdcF-family-protein	gnl|CDD|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	6.0474e-23
NZ_CP014859.1|WP_084642589.1|1202043_1202919_+|HD-domain-containing-protein	gnl|CDD|372434	pfam13023, HD_3, HD domain. HD domains are metal dependent phosphohydrolases.	1.39876e-30
NZ_CP014859.1|WP_069847113.1|1207840_1210141_+|3-oxoacyl-ACP-synthase	gnl|CDD|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	2.80027e-133
NZ_CP014859.1|WP_069853322.1|1205136_1205886_+|3-oxoacyl-ACP-reductase-FabG	gnl|CDD|273824	TIGR01830, 3-oxoacyl-_reductase_FabG, 3-oxoacyl-(acyl-carrier-protein) reductase. This model represents 3-oxoacyl-[ACP] reductase, also called 3-ketoacyl-acyl carrier protein reductase, an enzyme of fatty acid biosynthesis. [Fatty acid and phospholipid metabolism, Biosynthesis].	5.66186e-103
NZ_CP014859.1|WP_069847104.1|1198188_1199763_+|AfsR/SARP-family-transcriptional-regulator	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	3.20466e-37
NZ_CP014859.1|WP_069853319.1|1196995_1198189_+|glycosyl-transferase	gnl|CDD|273616	TIGR01426, Glycosyl_transferase, glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance].	6.51627e-137
NZ_CP014859.1|WP_069847102.1|1195400_1196510_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	1.2015e-144
NZ_CP014859.1|WP_069847115.1|1210137_1210869_+|nitroreductase-family-protein	gnl|CDD|380311	cd02062, Nitro_FMN_reductase, nitroreductase family protein. Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.	1.61987e-17
NZ_CP014859.1|WP_069853318.1|1190699_1191686_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.70573e-86
NZ_CP014859.1|WP_069847109.1|1205921_1206224_+|hypothetical-protein	gnl|CDD|181682	PRK09184, PRK09184, acyl carrier protein; Provisional.	3.76604e-08
NZ_CP014859.1|WP_069853321.1|1203217_1204831_-|FAD-dependent-monooxygenase	gnl|CDD|235704	PRK06126, PRK06126, hypothetical protein; Provisional.	4.45559e-122
NZ_CP014859.1|WP_069847099.1|1193277_1193883_+|dTDP-4-dehydrorhamnose-3,5-epimerase-family-protein	gnl|CDD|380337	cd00438, cupin_RmlC, RmlC carbohydrate epimerase, involved in dTDP-L-rhamnose production. RmlC (deoxythymidine diphosphate (dTDP)-4-keto-6-deoxy-D-hexulose 3, 5-epimerase or dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; also known as RfbC) is a carbohydrate epimerase involved in the production of dTDP-L-rhamnose, a precursor of the bacterial cell wall constituent, L-rhamnose. L-Rhamnose (6-deoxy-l-mannose) plays an important role in the cell-wall structure of many bacterial species. It has been found to contribute to the virulence of several species, including the Gram-negative Salmonella enterica and Vibrio cholerae, where it is present as a part of the O-antigen, and is essential for the growth of Gram-positive bacteria such as Streptococcus pyogenes. RmlC converts dTDP-6-deoxy-D-xylo-4-hexulose to dTDP-6-deoxy-L-xylo-hexulose by catalyzing the epimerization of the 5-methyl and 3-hydroxyl groups of hexulose, the third of four steps in the dTDP-L-rhamnose biosynthetic pathway. RmlC belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	8.56184e-68
NZ_CP014859.1|WP_084642591.1|1206220_1206745_+|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl|CDD|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	1.55387e-46
NZ_CP014859.1|WP_069847100.1|1193971_1195435_+|NDP-hexose-2,3-dehydratase-family-protein	gnl|CDD|367562	pfam03559, Hexose_dehydrat, NDP-hexose 2,3-dehydratase. This family includes a range of proteins from antibiotic production pathways. The family includes gra-ORF27 product that probably functions at an early step, most likely as a dTDP-4-keto-6- deoxyglucose-2,3-dehydratase. Its homologs include dnmT from the daunorubicin biosynthetic gene cluster in S. peucetius, a similar gene from the daunomycin biosynthetic cluster in Streptomyces sp. strain C5, eryBVI from the erythromycin cluster in S. erythraea and snoH from the nogalamycin cluster in S. nogalater. The proteins in this family are composed of two copies of a 200 amino acid long unit that may be a structural domain.	3.8053e-106
NZ_CP014859.1|WP_069847111.1|1206748_1207813_+|glycine-cleavage-system-protein-T	gnl|CDD|234742	PRK00389, gcvT, glycine cleavage system aminomethyltransferase GcvT.	5.48744e-39
NZ_CP014859.1|WP_069847097.1|1191783_1192614_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl|CDD|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	1.61233e-16
NZ_CP014859.1|WP_069853324.1|1210865_1212107_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	3.67999e-23

Protein sequences

>NZ_CP014859.1|WP_069847106.1|1199773_1200460_-|YdcF-family-protein
MSSRDREPAGAIEEITAQQWRAAELIWDYHQLGHELRTCDAAIALGSHDLGVATVTVELYAAGWFPLVVFSGGNSRTTRQRFPRGEAVHYREHAIELGMPATAILIEQQAANTGENITLSRALLAAQDIRPRRVLLICKPYAQRRAFATCARVWPAVDIVCVSEPLGFADYVLSIGDAKLVVDMLVGDLQRVIDYPELGFMVPQDVPAAVRTAYDQLVAAGFDSRLVS
>NZ_CP014859.1|WP_069847104.1|1198188_1199763_+|AfsR/SARP-family-transcriptional-regulator
MTVGIEFRIMGPLTVLRDGVALKFDGARERAVLSMLVLEANRIVSVGRLIDAVWAGAPPKSARAQIATCVSRLRRALGQAAGQSGADEVISTSNPGYTLNADPDTIDWSRFRSLVADSRREAALGNRQQAVTVLREALTQRRGVAFEGVHGMRCEAAGVEEAHLDAVEACVEMELELGAHQKVIAELTPVVAEHPLRERARVQLMLAQYRAGRRAEALRTYHDARRQLIDQIGLEPGPELRQLHERILRDAADLTPTPVMPAQQPEQQFVIPSQLPPLALPFAGRAQEERELDAALENQGATAPPVILAGPAGVGKTALALRWAHRRQDLFPDGQLFADLGDGRSGTRVRPDVVLDRFLRALGLPDRAIPADLVEKTALFRSMTAHRRLLVVLDGASDAEQVLPLLPGGIHCRVIITSCDPLDELVARQGAVRSFVGPLRPEESQELLVALVGLPMVAAEPDAAGRLALSSRGFPMALRMAAARLSSRPPRSLADLAPSLPLHCEELEDLQLDLAGRRARPSFA
>NZ_CP014859.1|WP_069853319.1|1196995_1198189_+|glycosyl-transferase
MGQHFLFMSHPDHGHVLPNLAVVTALVDRGHRVTYLTGETMVDLVTEAGATPLVYDSRYRQANFTDVAYDPLYLMTLLLSESASMLAKAEEQLGDDRPDAVSYDISMLYAGRILSRKWDIPAVQLIPMFASNGNYSYINSIYNSDGAEKSMPDWVGEQLARIGELMAVHGIEGSPQELWWEVPDFSVVNIPQSFQIEGDTFDERFAFVGPCLGRRAFFGEWSPPDNGLPIVLISFGAVFNEHSDFFHECVRAFTGMPWHAVITVAGGMDPADLGPLPPNVEVHRFVPHVAVLEHAQIAVTHGGMGTVMEALHTGTPMVVVPTSSIDGVTADRLAELNLGRTMKPEEVTAQRLIDAVLAVAADETIKRSTEEMREQIKAAGGATRAADEIEKYLARTV
>NZ_CP014859.1|WP_069847102.1|1195400_1196510_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MPTRVWDYLPEYENERAEILDAVETVFSSGQLVLGASVQGFESEFAAYHGVEHCVSLDNGTNAVRLGLQALGVGPGDEVITVSNTAAPTVVAIDAVGAVPVFVDIRRDDYLMDVEQVRAAITPRTKCLLPVHLYGQCVDMAPLEQLAAEHNLVILEDCAQSHGARHHGKIAGTMGKAAAFSFYPTKVLGAYGDGGATITSDDTVNQNLRRARYYGMEKVYYVVETPGSNSRLDEVHAEILRRKLPKLDDYVAGRRAVADRYAAGLADTDLMLPKVAEGNEHVYYVYVVRHPRRDEIIARLKERDIHLNISYPWPVHTMTGFAHLGYQPGSLPVTEELAEEIFSLPMYPSLPPEVQEKVISELREVLSTL
>NZ_CP014859.1|WP_069847100.1|1193971_1195435_+|NDP-hexose-2,3-dehydratase-family-protein
MSAPSRSSARPDSAESANSGGVQFADIDAFHRWYAVVADRTHMSVERLALDELDGWAYDETTGHIRHRSGKFFTVESLDVQVTSGPVQRWSQPIINQPEVGILGILVKEFDGVLHCLMQAKHEPGNHNGLQLSPTVQATKSNYTRVHGGRSVPYLDYFRDPDAADVIADTRQSEQGAWFYRKRNRNMIVEVTGEVELVDGFCWLSLDQLYELLSVPDLVNMDARTVLACLPFEGGRPALRRSAETEHPEAENAFVAALLRSEQAECGVHSTHEVLSWITDTRIRTDLHAERGSLAQLRDWRRADGRISHDSGLFFDVIGVGVDAGGREIASWTQPMIEQVGTGVVAFLVKRIDGVLHVLMHARTEPGYTDVTELAPTVQCVPQNYDLLPAEARPPFLDEVLAAEADRIRFDTILSEEGGRFFGARNRYLVVETDLDLAQEHRDHRWLTVCQLAELMRHSFYLNVQARSLVVCLRSLATTSTAPREAR
>NZ_CP014859.1|WP_069847099.1|1193277_1193883_+|dTDP-4-dehydrorhamnose-3,5-epimerase-family-protein
MKARELAVVGAVEFSPEIFPDDRGEFLSYYQEPVFAETLGHKLFPTAQASQSRSRRGVLRGIHFSRTPPGTAKYVHCARGSALDIVVDLRIGSPTFGQSDSTILDTVSHRAMYFPPGVGHAFVALEDDTVISYLLSENYVPANELAITPHDAELALRLPADLELIQSDRDRAAMTLAQARTQGLLPEYATCLKIQQGFPNP
>NZ_CP014859.1|WP_069847097.1|1191783_1192614_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MSIHSDQNLVEEFRANRGNLGGRFADSRILLLTSTDSAGAKHTTPVAYLQDGLGRLLVIASADSAGSPPAWYQHIVSEPNVEVETGSFTFPAETIALEAEERQEAFDRAAEADHRLADEQARTASLIPVLVLNPLGGRPNGDTWSESLKIIHDAFRRELRLLRKEIAASGPRLGAQLRINCLSLCAGLGHHHTMEDSGMLPAVDRSHPELADATRRLREEHQAVKLLLEELQRVVSTANPDPVVLLADVERLTSEVENHLDYEEQQLFPILDTLTP
>NZ_CP014859.1|WP_069853318.1|1190699_1191686_+|LacI-family-DNA-binding-transcriptional-regulator
MDVARAAGVSKSLVSLAIRGDAGVGSATREHILSVAHEIGYRSNLWARSLVRGRSQLVGVLLNDLHNTYHTDIVHGIEDAAAEQGLGVIISHGRREATVLAQRLEDVLALGVDGIVVISALLDPQLLRDAARRKPTVVVGRPPALPDTVGGVANHDERGARLAVEHLTSLGHRRIAHLTHSNRAAATARKQSYLDLMTALGYAEGIQVLDSEAGGETELLDSILVRRADAPTAVFASNDRRAASILGGALDAGLRVPEDLSIVGYDNTDLAASVRPGLTSVDQPRLAMGRLAMDILTEMLGGADARHEVVEPTLVVRGSTGRAAGTVN
>NZ_CP014859.1|WP_069847095.1|1189833_1190391_-|hypothetical-protein
MNYANPDTGRTALDHVPDALLLDFGGVIFETVKHPQGRAELATRIVELLRRAGQPLEAGFVRRSLDAALTALKHWKHASSRRVEPRELTHREIAADFLAADYPPGPRDVLIAEAAEVLDLVTSTLSAHVIRPGIGRLLACVRRTRHPARDRLQRAFRPQPSAHPRRTRARSGLRCPGVLRRGRHP
>NZ_CP014859.1|WP_069847093.1|1188755_1189862_-|HAD-IA-family-hydrolase
MYSDEVGIRKPNPRIIELAATALGVTADRCWYVGDTLDRDVVAGRRAEVAAVVVTRSHHTDAPPFGVAAEPDAVFDTPEGLADALEAAGPARSPVRTSIPAAKPARAALLIDHGGVISHSQPDPDAMGEFAAEVARRLTGAGEQVAPAQALELIEKGRERHHLRKQQRHRAHVETGAPLAEVQPVDFWRDLVGAELPERQRAILTAEAFDLMHLLGRAKSRRILRTGVRELLETCRDAGLAVVVVSNTINGRAVRAQCAEHDLDGLIGAYVCSDEAGVRKPDPTIVREALRVAAADPARTWFYGDKPENDAEAARACGITHRVIVRGGSTPDETVDRALTSGLVTTAVPDAGQLAALIAAEHRTDADA
>NZ_CP014859.1|WP_157420964.1|1201387_1201834_-|hypothetical-protein
MKPTVSMEQASGRWPTIRRYLLAKPRIAKITNPFLDWHCANASTTLPNEQIADALTEWADYFEWDLQQRTDELVADPARQHFLENWTDSMAYCCRRWAAWARGEDPGKPIPLHERRPDLARRGNAITDEIIAGLAVRSHTDDWQGTTP
>NZ_CP014859.1|WP_084642589.1|1202043_1202919_+|HD-domain-containing-protein
MQPLDPGDPRSPYIKIAASIRAAILSGELEPEAQLPTGDELAHFYGVTRATVSSATRILRDEGFLTSKPGGGVYVTGQASLPVAPGETHPLVGLAAYLHEAGHLKNLPRSGWALLGVRQAESVAEHSYRVGIIGMALAVMEGADPGRTAALCLMHDVHETRIGDVPSVGRAYVTTAVPQAVSAHQTAALPDEIASVYQAMTAEYEDTETLESKVAHDADKIETLLQAREYATQGYATEPWQDSSIQALRTDSAKQLAQAIITSDPRDWWRNFASSYQELRATTRARQGLKP
>NZ_CP014859.1|WP_069853321.1|1203217_1204831_-|FAD-dependent-monooxygenase
MTANEVEVLIIGGGPVGLATSIELSRHGVSSLLVEKHPSTSIFPKARLVTTRTMEIIRSWGVQAAVEEAGLPRGDSLALGIGPTLTSPDFRREVARIHEDAPQSPTYNYICAQDNFEVILRDLAESLPAGAVRFGTRMSELTVDEDGVTATISSEEGEKQVRARYVVAADGSRSGVRESLGVAVEGPPPLSYMVSVLFDADLGTLLQDRLGALYFVYGEVYCAVESVDNKRRWTLQTGYEPDEGESADDFTHERCIELVRAAVGVADLDVRIVGRMPWIQQAVVAEDFRKGRVFLVGDAAHVATPQGGFGMNCGIHDAHNLAWKLAAVLRGTAADALLDTYTTERRPIADWTVQESLRNALITIDMMEDRLTMQEAGDVQAHRRRAEGLVLGFHYDSPAITADGTQAPAPEDPYEIYLPTARPGHRAPHVWLSQQGTQVSTLDLLGTTLTLMTPAGNGWDTAAVQAADRLGVTLNIVQISPDNPEFPTSPTWATEYGLTESGAVLIRPDGHVAWRCAAGIPSADELVKVVDTVLCRG
>NZ_CP014859.1|WP_069853322.1|1205136_1205886_+|3-oxoacyl-ACP-reductase-FabG
MLFPEGSVALVTGGSRGIGRAAALDLAREGAHVLVNYARSESDAKEAVAEIEEAGGKATAICADVTDEAAVREMFQTVRSEYGRLDVLVTSAGITRDRHLVAMSLAQFREPMDVNVTGTFLVCREGLRIMQHQRSGAIVTLSSSSGLDGGFPGQTNYVASKGAIISFTKALAYEAAPHGVRANVVAPGFVATDMTRALSGPIRKQYESRIRLGRMGRPDEIARLVSFLASENASYVTGAVLVANGGGLG
>NZ_CP014859.1|WP_069847109.1|1205921_1206224_+|hypothetical-protein
MTIDELRARADVRKQTCAQIKKMIVSRLDLPIEPEWISDDQPLFGRGLELDSLDVLELYVAIEAEFGVALYDSDMSVFGSVSRLADSVNPALRTAPAAVA
>NZ_CP014859.1|WP_084642591.1|1206220_1206745_+|3-hydroxyacyl-ACP-dehydratase-FabZ
MTSTDATPGVTPEASTEAAPEKPKTLTNLSNDDIKELIPHRWPMLLLDRIEKVEPGVEGVAIKNVAGTEFWFQGHFPDEAILPGIVVIEAMAQLAGVVFSLAGAGKISYLTGVRSMRFKKRIVPGDRIVLSAVRTAGARGVGEYRVVARTDDQVAAEGVITITDPGANNTLRKV
>NZ_CP014859.1|WP_069847111.1|1206748_1207813_+|glycine-cleavage-system-protein-T
MESALTPVHPEGTVYGQVLEASVPLRYSTTEAEYEAIRGRAAVLDLGGSRLIQVRGSASGDFLQRVLARDVEYLTSERSTTSLILDDAGAIVDSVVVWGREDGAILESSCGAGTRLLEYLASQNSDEVEIVDRSDELTVIAVEGPYSWGVIGRLIDSELAALPLDSVVDTQWDGSDILFGRTGSSGEYGYKVIAAHEVAKKLWTQACEHAVPAGQEVLELAMLEVRQPVVRHEAPEGTGVLEVGAGWLVDITKESFVGRDAVLAAFAEQSGPRTIGFRGGEAVPAKGTRVSAGGQDIGEVVHAVYSVGLGAALGLARVDSDLAAAGLNLTAGDADIETLTSPYVSPKSWSIPIV
>NZ_CP014859.1|WP_069847113.1|1207840_1210141_+|3-oxoacyl-ACP-synthase
MALRPVVITGLGVICAIGRDPVEFWARLTSGESGITPISDGAYAAFDARFAGQVPTEWITDQLPEGDADLDRTAQLALVAARQAVQGAGLETDVASDRFGIVLGKCQATPDAEGRYQPMHRTGDVVAGKLGALGPRILVSTACAAGGNAVGLARDKILTGEADVVLAGGVDPLLFGTYAGFAGLQALSNNPCRPYSTSDGLNLGEGAAFLVVEPLDRVLARGGTPLAEVAGYGLSADAYHATAPDPTGRGGVSAMRRAFADAGMTADDVSYVSGHGTGTPANDSMEIKVMRTVFGERAGAVPTSSIKSFLGHTLGAAGAVEAVASVLALQNSTAPPTIGFDEPAEQAAPADNAESGPIPLDFVPNAARSFPIDTVVSNNYAFGGNNVSLVLTTPRGEREYEELPKKSVVISGIGPVSGLGIGVADLAEAIANGRQAPGEVPSLTGRTFAPRSLWRHMNDLSRLAIAASRLAWEDAALKLPRAAMEDIGVMFATAQGSVESTGGFDESVAANPNKPSVLSFSNVVLNATGGAVCQTLGLRGPTTTICNGGASASIALDCAVETIRAGKAEVVLVVAADETDRPAPDAPGTTPYGQDHAAPIPGSGAVAFVVESAEHCQARGGTAYAEILETRHAAGDGAESDTEMIKRSLDGLATGEVGLVVGAGVGGSADADEAAVLFDAVPGGLLTSPIGHTGDCQSASGAMNLAVAAMAVRDGVAPALTELTSPRFGAVDRYVTKPEMVGTVTSALALTAAPGSVRGTILLGKP
>NZ_CP014859.1|WP_069847115.1|1210137_1210869_+|nitroreductase-family-protein
MSSAAPFDLAETDRLLSTTRSVRRRLDLETPVPRELIEESLRLAVQAPTADNAQNWRWLVITDPEMKESLAGLFRRAWKFHKAEISTKSGRRRNSPQARKNEESAAALPEAIAKVPALILPCVVGKPPDSATIDSEWERLNAHKPADDPAHQVRMGQLRASTFYGSIFPAIWSLQLALRSRGLGSTITCMHLPFARQAAELLGIPSGVTQICMVPVAYTLGTNFRPAQRVDAGQRTFWEGWGK
>NZ_CP014859.1|WP_069853324.1|1210865_1212107_+|NAD(P)/FAD-dependent-oxidoreductase
MTHDDVDVVVIGGGIAGSSSASNLASHGLKVLMLEKQKAYTDLVRGEWLAPWGIRETQLLGVDDAFAAGGAWEIREWVQWDEVVHPDDAMAVDMTRFLPEVGGPQSFPHWKVCEAVTEQAVSLGAEVVMGASKIEVTAGPEPTVRYRTAEGEHEVKARMVLGASGRACAVGRQIGVSTTTEVHHWGAGMLVEGLDDWPVDVQAMGTEGDVMFMVFPQGYGRARLYLNFATGDQEKYRGADRVERFLSAYDLAALPDGGKAVQAAKQAGPLVVWPSVVSITDQKPVVDGVVLIGDEAGTSDTILGTGLSTSLRDARMVCEVLTGGDDWSPEAFEPFIKERNARMDRLHYGAKIMTKLQVEFGPHAVERRRRARRLMTENDAFQVTGLLNMVGPENVPEFGFSEFFVERLLKETV

Crispr_ID: NZ_CP014859_5

• CRISPR_ID: NZ_CP014859_5
• CRISPR_location: 1279760-1279910
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014859_5

Consensus_repeat	Method
ATCCGCCCCGCGTGCGCGGGGGTGTTCC	CRISPRCasFinder

spacers of NZ_CP014859_5

>5.1|1279788|33|NZ_CP014859|CRISPRCasFinder
GGTGGTTGAGTCGGACCGCAGTGGGGTGGTCGC
>5.2|1279849|34|NZ_CP014859|CRISPRCasFinder
CACAACGACGTCTACGGCGACGGCGAGTCGGGCA

CRISPR arrays and Neighbor proteins around NZ_CP014859_5

CRISPR arrays

The CRISPR arrays of NZ_CP014859_5

>merge|NZ_CP014859|5|1279760-1279910|CRISPRCasFinder
ATCCGCCCCGCGTGCGCGGGGGTGTTCCGGTGGTTGAGTCGGACCGCAGTGGGGTGGTCGCATCCGCCCCGCGTGCGCGGAGGTGTTCCCACAACGACGTCTACGGCGACGGCGAGTCGGGCATCCGCCCCCGCGCACGCGGGGGTGTTCC

>NZ_CP014859|5|5|1279760-1279910|CRISPRCasFinder
ATCCGCCCCGCGTGCGCGGGGGTGTTCC	GGTGGTTGAGTCGGACCGCAGTGGGGTGGTCGC
ATCCGCCCCGCGTGCGCGGAGGTGTTCC	CACAACGACGTCTACGGCGACGGCGAGTCGGGCA
TCCGCCCCCGCGCACGCGGGGGTGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069847197.1|1279185_1279698_+|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224759
NZ_CP014859.1|WP_157421361.1|1273137_1274304_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014859.1|WP_069847185.1|1270167_1271094_+|hypothetical-protein	unknown	unknown	gnl|CDD|188593
NZ_CP014859.1|WP_157421362.1|1287228_1287831_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
NZ_CP014859.1|WP_069847183.1|1268955_1269966_+|radical-SAM-protein	unknown	unknown	gnl|CDD|188593
NZ_CP014859.1|WP_069847205.1|1285021_1285603_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP014859.1|WP_069847192.1|1274382_1274988_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP014859.1|WP_069847201.1|1281731_1283657_-|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320687
NZ_CP014859.1|WP_069853333.1|1280588_1281257_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_084642621.1|1291298_1293251_-|metallophosphoesterase	unknown	unknown	gnl|CDD|277344
NZ_CP014859.1|WP_084642617.1|1275734_1277780_+|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319850
NZ_CP014859.1|WP_069847189.1|1272753_1273014_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|99777
NZ_CP014859.1|WP_069847203.1|1284380_1284965_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NZ_CP014859.1|WP_069847208.1|1288059_1291167_+|cytochrome-P450	unknown	unknown	gnl|CDD|99802
NZ_CP014859.1|WP_069847199.1|1280073_1280592_+|hypothetical-protein	unknown	unknown	gnl|CDD|183384
NZ_CP014859.1|WP_069847209.1|1293487_1293685_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847195.1|1277828_1278980_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014859.1|WP_157420969.1|1285635_1287138_-|MFS-transporter	unknown	unknown	gnl|CDD|184957
NZ_CP014859.1|WP_069847187.1|1271414_1272521_+|winged-helix-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|377630
NZ_CP014859.1|WP_069847194.1|1275291_1275573_+|metal-sensitive-transcriptional-regulator	unknown	unknown	gnl|CDD|376835

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069847197.1|1279185_1279698_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	7.1458e-09
NZ_CP014859.1|WP_157421361.1|1273137_1274304_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	3.30387e-85
NZ_CP014859.1|WP_069847185.1|1270167_1271094_+|hypothetical-protein	gnl|CDD|188593	TIGR04078, radical_SAM_domain_protein_protein, peptide modification radical SAM enzyme, YydG family. Members of this radical SAM protein family for peptide modification occur only in the context of members of family TIGR04077, which average about 50 amino acids in length. In Bacillus subtilis, this protein (YydG) appears to act on its cognate target peptide (YydF) prior to its export, and result in the creation of a signaling molecule that induces the LiaRS two-component system. [Regulatory functions, Protein interactions].	1.79217e-08
NZ_CP014859.1|WP_157421362.1|1287228_1287831_-|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	1.85125e-08
NZ_CP014859.1|WP_069847183.1|1268955_1269966_+|radical-SAM-protein	gnl|CDD|188593	TIGR04078, radical_SAM_domain_protein_protein, peptide modification radical SAM enzyme, YydG family. Members of this radical SAM protein family for peptide modification occur only in the context of members of family TIGR04077, which average about 50 amino acids in length. In Bacillus subtilis, this protein (YydG) appears to act on its cognate target peptide (YydF) prior to its export, and result in the creation of a signaling molecule that induces the LiaRS two-component system. [Regulatory functions, Protein interactions].	1.07111e-20
NZ_CP014859.1|WP_069847205.1|1285021_1285603_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.34734e-14
NZ_CP014859.1|WP_069847192.1|1274382_1274988_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	5.99739e-09
NZ_CP014859.1|WP_069847201.1|1281731_1283657_-|M48-family-metalloprotease	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	1.14776e-35
NZ_CP014859.1|WP_069847203.1|1284380_1284965_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	4.57426e-85
NZ_CP014859.1|WP_084642621.1|1291298_1293251_-|metallophosphoesterase	gnl|CDD|277344	cd07399, MPP_YvnB, Bacillus subtilis YvnB and related proteins, metallophosphatase domain. YvnB (BSU35040) is an uncharacterized Bacillus subtilis protein with a metallophosphatase domain. This family includes bacterial and eukaryotic proteins similar to YvnB. YvnB belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.81608e-74
NZ_CP014859.1|WP_084642617.1|1275734_1277780_+|heavy-metal-translocating-P-type-ATPase	gnl|CDD|319850	cd07552, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to Archaeoglobus fulgidus CopB, a Cu(2+)-ATPase. Archaeoglobus fulgidus CopB transports Cu(2+) from the cytoplasm to the exterior of the cell using ATP as energy source, it transports preferentially Cu(2+) over Cu(+), it is activated by Cu(2+) with high affinity and partially by Cu(+) and Ag(+). This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP014859.1|WP_069847189.1|1272753_1273014_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|99777	cd06170, LuxR_C_like, C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.	8.66725e-10
NZ_CP014859.1|WP_069847208.1|1288059_1291167_+|cytochrome-P450	gnl|CDD|99802	cd06206, bifunctional_CYPOR, These bifunctional proteins fuse N-terminal cytochrome p450 with a cytochrome p450 reductase (CYPOR). NADPH cytochrome p450 reductase serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via FAD and FMN. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	1.3849e-142
NZ_CP014859.1|WP_069847199.1|1280073_1280592_+|hypothetical-protein	gnl|CDD|183384	PRK11924, PRK11924, RNA polymerase sigma factor; Provisional.	3.25698e-14
NZ_CP014859.1|WP_069847195.1|1277828_1278980_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	5.37458e-35
NZ_CP014859.1|WP_157420969.1|1285635_1287138_-|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	4.00204e-87
NZ_CP014859.1|WP_069847187.1|1271414_1272521_+|winged-helix-DNA-binding-domain-containing-protein	gnl|CDD|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	1.7881e-58
NZ_CP014859.1|WP_069847194.1|1275291_1275573_+|metal-sensitive-transcriptional-regulator	gnl|CDD|376835	pfam02583, Trns_repr_metal, Metal-sensitive transcriptional repressor. This is a family of metal-sensitive repressors, involved in resistance to metal ions. Members of this family bind copper, nickel or cobalt ions via conserved cysteine and histidine residues. In the absence of metal ions, these proteins bind to promoter regions and repress transcription. When bound to metal ions they are unable to bind DNA, leading to transcriptional derepression.	5.65624e-31

Protein sequences

>NZ_CP014859.1|WP_069847197.1|1279185_1279698_+|winged-helix-turn-helix-transcriptional-regulator
MEEAPQPADDTERSGRILDGLRAFGANYTEFTDRFAAWLGLHSTDARALVEILYAEDKGTPLSPTRLSERLALTTGATTNLLNRLERLGHIVRTREQADRRAVTLRSSKEIEAPAREFFGPLAVHLDALVAQYPPEQLDQFERFLDGLRVSMNELLAEQAEASGRSEGKP
>NZ_CP014859.1|WP_069847195.1|1277828_1278980_-|cytochrome-P450
MPDAARPVVNPFAPVDRPHTEPDPTRAALRVAGPISRSTAPTDGPVWIVTTEALAKEVCSHPDIAKDPAFAPPYWDPAEAGLERTAAEQPSLTTLDGPAHAELRRAHAPLFSAKRIRAQSDRIHQIARELLTEAAARGPVVDLMAGFTTRYPLTVLLDLLGIPLDLVDEATDACLMMVNGVRGDQGKAIGALAELAAEGLRADSHGLAAELRDRLPAGTAEAELRYHLFALIFAGQLTTDSAVGFLIARALGEAAPHQDTVHDLVDETLRQHAPAPFSLWRFTTTEVELAGVRLPARTPLLVDILGINTDPARTSGTDLTFGSGAHFCIGAQLAREELRAVVTVLRTDFPAARLAMPATEIRQVGPGGIMGSRLAMLPVALRG
>NZ_CP014859.1|WP_084642617.1|1275734_1277780_+|heavy-metal-translocating-P-type-ATPase
MHPQSHDHDHDGSHSVDRQHQHTGHAGHGSHAAAFRDRFWLSLALTIPVVLASHMIADLLGYTVPTWAGWVAPVLGTVVFLYGGQPFLTGAVGELRARTPGMMTLVALAITVAFVASALTTFGVAGLELDFWWELALLVVIMLLGHWLEMRALGQATGALDALAELLPDSAERIAEDGSISSVGLGELAVDDVVLVRSGGRVPADGVVTEGAAELDESMITGESNTVRRSVGDRVVAGTVATDSSIRVRVQAIGSDTALAGIARLVEQAQSSKSRAQALADRAAAALFWFALIVGALTFVVWLVIGDPTTAVERMVTVLVIACPHALGLAIPLVIAISTSMSAKAGILVTDRLALERMRTIDAVVFDKTGTLTKGRPVVTEVRAAPGGSRSEVLALAAAAEIDSEHPLAAAIVAAAREEGPIPEARDFRSLTGRGVQAVVDGATIAVGGPGLLAEREIRPPEDLAAETQSWAARGATVLHVLRDGVVLGAVALADEVRPESREAIEALHRHGVRVMMITGDARPVAEAVAADLDIDEVFAEVLPADKDSKVVELQERGRRVAMVGDGVNDAPALARAEVGIAIGAGTDVAIESAGVVLASDDPRGVLAVRRLSVAAHRKMWQNLAWATGYNLLTVPLAAGVLAGVGFVLPPAVGAVVMSLSTIVVAVNAQLLRRVKLTESA
>NZ_CP014859.1|WP_069847194.1|1275291_1275573_+|metal-sensitive-transcriptional-regulator
MRGYTEDKDGYLKRLRRIEGQIRGLQRMVEADEYCIDVLTQISAATKALQSVSIGLIDEHLKHCVAEAIAEGGEVANEKVREASEAVARLVRS
>NZ_CP014859.1|WP_069847192.1|1274382_1274988_+|TetR/AcrR-family-transcriptional-regulator
MADARALGLRADAARNYERIVVAAGQAFEEVGPAVTLEQVARQAGVGVATVYRRFRNRDQLVRAVVEHVITTEIQPVDIVASDDPWQDLTDFLNRSLDALTGRRVMIALARETDAIGPEAFAPFLRWMDELAGRLVDAGLVRPELVGQDLGAVIIMVLAMTQVRGESDSPARRRYLALLLDGLRPTSNVLPGVPLEPIMPC
>NZ_CP014859.1|WP_157421361.1|1273137_1274304_+|cytochrome-P450
MRRERFDPTAELGESRRAEGIRLVDTPFGESVHLVTRYEDVRMVLADTTRFGNDRAAALAGPAVEYTEEEARMRAGQLLALDPPDHTRIRRLLTPEFTMRRMRRLEPRIVEIVDAALDDLENAGRPADLVAHFGLPVPSLVICELLGVPYADRAEFQRRSDQMLDLSATDQQRKVAEDEIRLYLAELIARTMAAPNDDLLGMLVREHGTELTADELVGIATILLIAGHETTANMLSLGTLALLTHPEQLAMVRDDPAAVEPAIDELLRWLSIVHAGVARVAKTDTEVAGRSVKAGELLLMSLPGANRDPALREDPDRFDITRGVSGHVAFGHGVHHCIGAPLARMELRIGFPALLRRFPKLALAVPFEEVGFRSNHAIFGVNSLPITW
>NZ_CP014859.1|WP_069847189.1|1272753_1273014_+|helix-turn-helix-transcriptional-regulator
MGRREPGALSPRQQELLSLLVAGHSAESCARLMGIALGTVRNYIKDMWIELGLHGLAALIDWGIEHGYGTSGGKPDEPADGPTGQN
>NZ_CP014859.1|WP_069847187.1|1271414_1272521_+|winged-helix-DNA-binding-domain-containing-protein
MTVLDTRALNRATLARQLLLERSDLPVSDAIAHLGGLQAQEPQEPFIGLWSRLRDFDPTTLSDLLIGRTVVRTHLMRRTVHLLTAADTLAWRTRHNPMLRQRVLGVYRNELADVDLDELAAEGREVLADGEPRSMSELARAVAGRWPEPGPRPLGEMLVAALLPMVQLPPRGLWRTKAGVRNLLLSSWVGREIDPPAPEGTDPVGAALVRRYLAAFGPAASADLRAWCGLAGLPAAVASIRDELVTFRDERGRTLLDLRDAPRPDPGVPAPVRFLPAFDNAILGYHDRSRIIDDAHRGLSVAGIRVVLVDGRVAATWLVRDDTVSITPLRELAPTDRTAVAEEGEAVAAFLTDGDSSRIEITEVGADG
>NZ_CP014859.1|WP_069847185.1|1270167_1271094_+|hypothetical-protein
MESNPRKKKKLDPATAIDLLTTGAKYGKSFLDLSGGEAMLFPEEVLEVASAARDLGYYICLNTNAYWARTPDKAVETLAGLKAAGVQAVFPSASAYHLRYVPLERVKNLRAACRELDMVYELNWVYSDQPEADEHIKQEMGLEGETLYYDGLVTAGNNSETIANLEKIYTRRTPEQLDDCLSVHLAVNPHGHVVTSCNMTYDNAKFKDTPFFLGNFHEQSFEDILRAEAQSPVLQFIYHNPHPALHNLMANDQAFGDYYRETFSERSYFSVIDYYLELFRDQRTAAWLQSNLPAVVEEQQRQRALTTV
>NZ_CP014859.1|WP_069847183.1|1268955_1269966_+|radical-SAM-protein
MADSPDGPPPIWDRFSANERLAINFTLTCNLSCAHCIVESSPQRTERLTLDEVRTALESGRHNGKRHVTFSGGEVFLYPEQMVEVISFATGLGFVVDVESNAFWARSEAIARKKLAPFVEAGLAGMALSADAFHVEFFPVDRTINAARIGREFGLVTEINFCPSTQTEVDEQIKAALTAAGEPFIMNELLDRGRGKGLLNISIGRRVDELPDCDSLTTTVHATGDMYACCELDISTDAMKRTPVFLGSIRVGDRTQQERDEREHLVTSFYDPNSPIYFRKLVEEHPLFQGLTSERYQNICDFCLLALRDPARVAALREILAAHRSESLPVGAGVDK
>NZ_CP014859.1|WP_069847199.1|1280073_1280592_+|hypothetical-protein
MHRIRRPPPAERAAAFTEAYHRLYPRVLAFMLRRVGDRGVAEDLASKVFQIGWEHVDSRLLWTNAWFFGTARTVLAEHHHRAPRLAELHRRPAVEFGRPPATGDDLRALAALDALDSLTEEQREVLLLHYWEGLDSVEVAYALRRSRSAIWLRLYRARRAFRAAYLSRSGSW
>NZ_CP014859.1|WP_069853333.1|1280588_1281257_+|hypothetical-protein
MSRVLVKSLIIRANPVPTPPPDLLSGRAAAELADLVGEQQSAEFRPQPPAPGRRGPVLAVAVALSVILVVGVVGLVLFFSDDRRGQRTPVVTDEPYYASTEELVAEADLIVRGRIDATHRQTMDDLPEIRAEVTVLASVGDTVAVGDTIDVAYVIRGAAPSTADVAEGGEYVLLLKDWGDGRRTLVNSTQGSYTVAEGRAIAGQHNEVGLGGELLAELGLGE
>NZ_CP014859.1|WP_069847201.1|1281731_1283657_-|M48-family-metalloprotease
MRGAVRAFLAVLLLILFPIFVLALGIGGTIAGINIGGRGGIYLAIVAVGLMLALGFGLVQALRTRLTPPDGPRLTRQEQPMLWQLVDELAANAQTRPPDEIILVPEINAAVQEDARGLGLQAGRRYMMIGLPLLAGLNVSELRSVLAHELGHYGGGHTRLLAITYRGAETLRRTVGRLDSGPARWILNGYARLYLMVSRSATRSQELQADAYSVAAAGRFTASEALRKIATMDMFWEAYADRFLNLPQLAQRTPDILLGFRFFLDAPENQRIRAEYEPKVLDAESSSVYDSHPTIRKRIAAIQNLPDNPAAPDQRPGWSVIMNPAQVLPAAEGVLYIRGEIGPKAGWDEIARLGCAELAAKNAARLAEAARQSGAAPSGALGEILNAVGRGEMVRLIAPLVREGIDPNEQIDAVRNLLTGLLGAVIVTALISQGRAHHELRWGGPAQVIGPNGPLDVAELVGPAVANPGLVPQFVARLQQLGVPLDFVRLPAPEAAAQQRPNDGQPQLMSVAPGIMAFRKTWDAFVTDIGLLLIPVKMSKLAGQNLSGMMGQGGQALNGRINTLLENGAAGLFARDDGRWVLNQNIVDGEHKKFLTGGGKIKLDFADGTKAEIRTDSDENFEVLLTYFSEVAAQSRQQAGG
>NZ_CP014859.1|WP_069847203.1|1284380_1284965_-|sugar-O-acetyltransferase
MTDAAHGAGDDTRSNREKMLAGEPYVFDAELAEHNDRAARLAARFGEIAPHDAAAGRAILEELLGAIGEETVIRGPLYVDYGSGLHIGARSFANFGLVALDVARITIGDDVQIGPNVQLLTPTHPVAPEPRRQKFESAEPITIGDNVWLGGGAIVLAGVTIGDNTVVGAGAVVTKDLPANVVAVGNPAKVVREI
>NZ_CP014859.1|WP_069847205.1|1285021_1285603_-|TetR/AcrR-family-transcriptional-regulator
MARTAGRQAGETKRLILAAATRLIGRHGTGVPLADIAEAAGVSKGGLLYHFPNKEELLNGLATDLMDRFRHDVEQAATEEAEGTPGRLTRAYIRVSFEHGGDDVELREHIALAVHLMFEPGLEELAQRDAQRWRTALLDDGLDQTISRMIIAATDGTNSAPLWGAVLSDADHVALQADLIALTHGRFPGLPGD
>NZ_CP014859.1|WP_157420969.1|1285635_1287138_-|MFS-transporter
MSEVLSPARRWASLAVLVGAVLLLAIDATVLYLAVPSLTAELSPTATQVLWIGDVYSLVLAGLLVTMGNLADRIGRKRLLLIGATAFGAASVLAAFAPSSEVLIVARLLLGVAGATIMPSTLSLIRNIFTEPIERTRAVAIWSAAAASGIALGPLVGGALLERFWWGSVFLINLPVMLLVLVVGGWLLPESRNPNPGRFDLISSGLSMLAIIPFVYTIKQLTSGSFGLGVVAAIVASVVGAVLFVHRQRRVAAPMIDVELFRNPAFSGAVLVNFISVFALSGVLFFFSQYLQLARGLGPLEAGVAQLPAALSAMAAVAAVGFLLTRLGRGRAIATALLIGAAGLGLLAALEGSEELIWVLLPMIPLGLGIGIAETLSVDAVVSSVRPTKAGAAASVAETAYELGVALGIAVLGSVITVLYRGNLDLPTEVAGEVAARAEDSLASATAILEPGSSALTAAQEAFMSAMQTTTLVAGAVMVVAAIVAFTLIPNDKAAVSTEH
>NZ_CP014859.1|WP_157421362.1|1287228_1287831_-|TetR-family-transcriptional-regulator
MSADERRRQLVGAALRVMKRDGIAAATTRAICTEAGMPHGAFHYCFHSKKELYAAVLASDIEIDLAAAWPRISAETSPAENIRTLLLAFWSQIEADPDSQLVLYDLGSFVLRDPELQELPRQQHLAGLERAIGYIRRLRDEASLTLLHEERLLAELTLATLNGVAWSWLAHRDNHAAREALSRFADLLATLVRSADDRAG
>NZ_CP014859.1|WP_069847208.1|1288059_1291167_+|cytochrome-P450
MTSQLAEDSPRIPGPAPLPVLGNLLEMLRAPQETSIELTADYHARYGGIFALDIVGNRQIFASDHRLVAEMCSSPLWSKSVHDALEQIRDFGGDGLFTAYSEEPNWGRAHRLLMPAFGTMAMKDYFPQMLDIAEQLMVRWQRFGSDHTIDVAEDMTRLTLDTIALCAFNVRFNSFYSEKPHPFVGAMVRSLVEAGARPERLPGVQPFLVGTNRQYRTDIAAMQRITDDIVATRNGLPAEDQPDDLLQRMLTAADPLTGEKLSEENIRHQLVTFLVAGHETTSGLLSFATHQLLANPDVLARAREVVDEVLGNRTPRFEDLADLGYLGQILRETLRLHPTAPAFALTPSEPTTLGGHRITPDDSVMVILPVLHQDPEVWPQPQRFDPDRFAPDRMDRIPEYAWMPFGHGARACIGRPFALQEATLVLAMMLQRFDIALADPDYRMTISETLTIKPKDLTIKARARSAAPQPRSEPATAAPHAPTAAEVRPSHGTPMLVLFGSNGGSSESLARTIAGDGHARGWNTEVAPLDDHAGTLPTEGPVVIVTSSYNGTPPDNARRFVDWLTESEPELTGVDYLVLGCGSLDWAATYQRIPTRIDEAMAAAGANRIRERGVTDARTDFFGDWERWYRPLWSELAARYGVADTAPTGPRYRITPTNAPRPERTDATAVVVQNRELTTGTRSKRHLELRLPEGRTYRTGDYLSVLPQNHPELVTRMLTRLGIDPEHLVSIASDAPNGRIPVGLPIRVDDLLTRHTDLSAPATPGVIAALAETTRCTPERRELTELANQAESGERRPSLLHLLERFASCPVDLAWVLERLPEPRARQYSISSAAEVQTEVALTVSVVEGPDRAGSGTYRGAASSYLQRTHPGDRLTVALAAPQEEFRPPADNSVPVVMIAAGSGIAPFRAFIAARRARAEKGEPHGANLLFFGCRHPDSDDLYAEEFAPLVAAGTLQVHRAFSRRPDGDVHYVQHRLWAERRSVLDLVEQGAHLYVCGDVTGMGPAVEECLRRIGPDEDWLDRLRAAGRYATDLF
>NZ_CP014859.1|WP_084642621.1|1291298_1293251_-|metallophosphoesterase
MDDPRRTDRDPAEAAASPAEATQAAGGPALGRRTLLHAAAAVPVIGAAASLPAVTAPAAHAQDEASTASAGRGADLESTRFVIAVLPDTQYLFDEDSSDPTPLRDAFRHVVDRRREEDIVFLAHLGDVTEHGSQHEIDLAERAFRFLDRKLPYSVLAGNHDVDGSTDDQRGDSPYLAAFGPDRFRRSSTYLGSSPGGYNSAHVLRAGDRDWLLLALDWRISDTGLDWARGVLAEHPTLPTILTTHDLAFASDDGIAQLSEHGRRLWDGLINDHDQIFLTLNGHYWPSGRTVLQNAAGNDVHVHIANYQDMYYGGAATLRYYSFDLVRGVIDVETFSPWLLGIDREDRSPLEAENVERTGEVDRFSVAIDFEKRFAGFSGVTPPAARPADEVVGRGTVAYWRFDESGLGETGADGNAVNEGTVARDLTGNGNDLVATRLHNGPADVLTFSADHHVDQPAHASLRFDGAKDPNRGALLRAVTEAPINSMTFESGYTIELFAKLPDPMVGDHSFMGLLSWEGRAGDAGKTSGWSQDEPTCSLNLSGERFLQYVVYPNDRDADPTSWSHALPMGRWMHLAVVNDGRQTVVYVDGSKIARNPTQRSKGITTLGKPFVIGGTQFAEEYSHGFYGWIGDVRISSRALRTTEFLTTRR
>NZ_CP014859.1|WP_069847209.1|1293487_1293685_-|hypothetical-protein
MTTITILGSGTVATALAGPLHAAGHQVIIDLGGVHTALGREAFLLMVRSLVGALGPVPFGMAVAR

Crispr_ID: NZ_CP014859_6

• CRISPR_ID: NZ_CP014859_6
• CRISPR_location: 1281324-1281535
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP014859_6

Consensus_repeat	Method
ATCCGCCCCGCGCACGCGGGGGTGTTCCG	PILER-CR
ATCCGCCCCGCGCACGCGGGGGTGTTCC	CRISPRCasFinder
ATCCGCCCCGCGCACGCGGGGGTGTTCC	CRT

spacers of NZ_CP014859_6

>6.1|1281353|32|NZ_CP014859|PILER-CR
GCAGCCGCCGAGGGGATCACCGCGATCCGTCA
>6.2|1281414|32|NZ_CP014859|PILER-CR
GATGCCGAGAAGGCCAATGATCAAGAGTGGTG
>6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT
GGCAGCCGCCGAGGGGATCACCGCGATCCGTCA
>6.4|1281413|33|NZ_CP014859|CRISPRCasFinder,CRT
CGATGCCGAGAAGGCCAATGATCAAGAGTGGTG
>6.5|1281474|34|NZ_CP014859|CRISPRCasFinder,CRT
GACATGGTCACGGACGACACCCGAGGCCGAGCAG

CRISPR arrays and Neighbor proteins around NZ_CP014859_6

CRISPR arrays

The CRISPR arrays of NZ_CP014859_6

>merge|NZ_CP014859|6|1281324-1281535|PILER-CR,CRISPRCasFinder,CRT
ATCCGCCCCGCGCACGCGGGGGTGTTCCGGCAGCCGCCGAGGGGATCACCGCGATCCGTCAATCCGCCCCGCGCACGCGGGGGTGTTCCCGATGCCGAGAAGGCCAATGATCAAGAGTGGTGATCCGCCCCGCGCACGCGGGGGTGTTCCGACATGGTCACGGACGACACCCGAGGCCGAGCAGACCCGCCCCGCGCACGTCGGGTGCGTTC

>NZ_CP014859|6|4|1281324-1281474|PILER-CR
ATCCGCCCCGCGCACGCGGGGGTGTTCCG	GCAGCCGCCGAGGGGATCACCGCGATCCGTCA
ATCCGCCCCGCGCACGCGGGGGTGTTCCC	GATGCCGAGAAGGCCAATGATCAAGAGTGGTG
ATCCGCCCCGCGCACGCGGGGGTGTTCCG

>NZ_CP014859|6|6|1281324-1281535|CRISPRCasFinder
ATCCGCCCCGCGCACGCGGGGGTGTTCC	GGCAGCCGCCGAGGGGATCACCGCGATCCGTCA
ATCCGCCCCGCGCACGCGGGGGTGTTCC	CGATGCCGAGAAGGCCAATGATCAAGAGTGGTG
ATCCGCCCCGCGCACGCGGGGGTGTTCC	GACATGGTCACGGACGACACCCGAGGCCGAGCAG
ACCCGCCCCGCGCACGTCGGGTGCGTTC

>NZ_CP014859|6|3|1281324-1281535|CRT
ATCCGCCCCGCGCACGCGGGGGTGTTCC	GGCAGCCGCCGAGGGGATCACCGCGATCCGTCA
ATCCGCCCCGCGCACGCGGGGGTGTTCC	CGATGCCGAGAAGGCCAATGATCAAGAGTGGTG
ATCCGCCCCGCGCACGCGGGGGTGTTCC	GACATGGTCACGGACGACACCCGAGGCCGAGCAG
ACCCGCCCCGCGCACGTCGGGTGCGTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069847197.1|1279185_1279698_+|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224759
NZ_CP014859.1|WP_157421361.1|1273137_1274304_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014859.1|WP_069847205.1|1285021_1285603_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP014859.1|WP_157421362.1|1287228_1287831_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
NZ_CP014859.1|WP_084642621.1|1291298_1293251_-|metallophosphoesterase	unknown	unknown	gnl|CDD|277344
NZ_CP014859.1|WP_069853333.1|1280588_1281257_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847201.1|1281731_1283657_-|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320687
NZ_CP014859.1|WP_069847203.1|1284380_1284965_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NZ_CP014859.1|WP_069847192.1|1274382_1274988_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP014859.1|WP_084642617.1|1275734_1277780_+|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319850
NZ_CP014859.1|WP_069847189.1|1272753_1273014_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|99777
NZ_CP014859.1|WP_069847213.1|1294433_1295540_+|DNA-alkylation-repair-protein	unknown	unknown	gnl|CDD|226785
NZ_CP014859.1|WP_069847211.1|1293796_1294198_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP014859.1|WP_069847208.1|1288059_1291167_+|cytochrome-P450	unknown	unknown	gnl|CDD|99802
NZ_CP014859.1|WP_069847199.1|1280073_1280592_+|hypothetical-protein	unknown	unknown	gnl|CDD|183384
NZ_CP014859.1|WP_069847209.1|1293487_1293685_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847195.1|1277828_1278980_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014859.1|WP_157420969.1|1285635_1287138_-|MFS-transporter	unknown	unknown	gnl|CDD|184957
NZ_CP014859.1|WP_069847187.1|1271414_1272521_+|winged-helix-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|377630
NZ_CP014859.1|WP_069847194.1|1275291_1275573_+|metal-sensitive-transcriptional-regulator	unknown	unknown	gnl|CDD|376835

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069847197.1|1279185_1279698_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	7.1458e-09
NZ_CP014859.1|WP_157421361.1|1273137_1274304_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	3.30387e-85
NZ_CP014859.1|WP_069847205.1|1285021_1285603_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.34734e-14
NZ_CP014859.1|WP_157421362.1|1287228_1287831_-|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	1.85125e-08
NZ_CP014859.1|WP_084642621.1|1291298_1293251_-|metallophosphoesterase	gnl|CDD|277344	cd07399, MPP_YvnB, Bacillus subtilis YvnB and related proteins, metallophosphatase domain. YvnB (BSU35040) is an uncharacterized Bacillus subtilis protein with a metallophosphatase domain. This family includes bacterial and eukaryotic proteins similar to YvnB. YvnB belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.81608e-74
NZ_CP014859.1|WP_069847192.1|1274382_1274988_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	5.99739e-09
NZ_CP014859.1|WP_069847201.1|1281731_1283657_-|M48-family-metalloprotease	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	1.14776e-35
NZ_CP014859.1|WP_069847203.1|1284380_1284965_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	4.57426e-85
NZ_CP014859.1|WP_084642617.1|1275734_1277780_+|heavy-metal-translocating-P-type-ATPase	gnl|CDD|319850	cd07552, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to Archaeoglobus fulgidus CopB, a Cu(2+)-ATPase. Archaeoglobus fulgidus CopB transports Cu(2+) from the cytoplasm to the exterior of the cell using ATP as energy source, it transports preferentially Cu(2+) over Cu(+), it is activated by Cu(2+) with high affinity and partially by Cu(+) and Ag(+). This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP014859.1|WP_069847189.1|1272753_1273014_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|99777	cd06170, LuxR_C_like, C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.	8.66725e-10
NZ_CP014859.1|WP_069847213.1|1294433_1295540_+|DNA-alkylation-repair-protein	gnl|CDD|226785	COG4335, COG4335, DNA alkylation repair enzyme [DNA replication, recombination, and repair].	9.67324e-33
NZ_CP014859.1|WP_069847211.1|1293796_1294198_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	6.37796e-40
NZ_CP014859.1|WP_069847208.1|1288059_1291167_+|cytochrome-P450	gnl|CDD|99802	cd06206, bifunctional_CYPOR, These bifunctional proteins fuse N-terminal cytochrome p450 with a cytochrome p450 reductase (CYPOR). NADPH cytochrome p450 reductase serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via FAD and FMN. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	1.3849e-142
NZ_CP014859.1|WP_069847199.1|1280073_1280592_+|hypothetical-protein	gnl|CDD|183384	PRK11924, PRK11924, RNA polymerase sigma factor; Provisional.	3.25698e-14
NZ_CP014859.1|WP_069847195.1|1277828_1278980_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	5.37458e-35
NZ_CP014859.1|WP_157420969.1|1285635_1287138_-|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	4.00204e-87
NZ_CP014859.1|WP_069847187.1|1271414_1272521_+|winged-helix-DNA-binding-domain-containing-protein	gnl|CDD|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	1.7881e-58
NZ_CP014859.1|WP_069847194.1|1275291_1275573_+|metal-sensitive-transcriptional-regulator	gnl|CDD|376835	pfam02583, Trns_repr_metal, Metal-sensitive transcriptional repressor. This is a family of metal-sensitive repressors, involved in resistance to metal ions. Members of this family bind copper, nickel or cobalt ions via conserved cysteine and histidine residues. In the absence of metal ions, these proteins bind to promoter regions and repress transcription. When bound to metal ions they are unable to bind DNA, leading to transcriptional derepression.	5.65624e-31

Protein sequences

>NZ_CP014859.1|WP_069853333.1|1280588_1281257_+|hypothetical-protein
MSRVLVKSLIIRANPVPTPPPDLLSGRAAAELADLVGEQQSAEFRPQPPAPGRRGPVLAVAVALSVILVVGVVGLVLFFSDDRRGQRTPVVTDEPYYASTEELVAEADLIVRGRIDATHRQTMDDLPEIRAEVTVLASVGDTVAVGDTIDVAYVIRGAAPSTADVAEGGEYVLLLKDWGDGRRTLVNSTQGSYTVAEGRAIAGQHNEVGLGGELLAELGLGE
>NZ_CP014859.1|WP_069847199.1|1280073_1280592_+|hypothetical-protein
MHRIRRPPPAERAAAFTEAYHRLYPRVLAFMLRRVGDRGVAEDLASKVFQIGWEHVDSRLLWTNAWFFGTARTVLAEHHHRAPRLAELHRRPAVEFGRPPATGDDLRALAALDALDSLTEEQREVLLLHYWEGLDSVEVAYALRRSRSAIWLRLYRARRAFRAAYLSRSGSW
>NZ_CP014859.1|WP_069847197.1|1279185_1279698_+|winged-helix-turn-helix-transcriptional-regulator
MEEAPQPADDTERSGRILDGLRAFGANYTEFTDRFAAWLGLHSTDARALVEILYAEDKGTPLSPTRLSERLALTTGATTNLLNRLERLGHIVRTREQADRRAVTLRSSKEIEAPAREFFGPLAVHLDALVAQYPPEQLDQFERFLDGLRVSMNELLAEQAEASGRSEGKP
>NZ_CP014859.1|WP_069847195.1|1277828_1278980_-|cytochrome-P450
MPDAARPVVNPFAPVDRPHTEPDPTRAALRVAGPISRSTAPTDGPVWIVTTEALAKEVCSHPDIAKDPAFAPPYWDPAEAGLERTAAEQPSLTTLDGPAHAELRRAHAPLFSAKRIRAQSDRIHQIARELLTEAAARGPVVDLMAGFTTRYPLTVLLDLLGIPLDLVDEATDACLMMVNGVRGDQGKAIGALAELAAEGLRADSHGLAAELRDRLPAGTAEAELRYHLFALIFAGQLTTDSAVGFLIARALGEAAPHQDTVHDLVDETLRQHAPAPFSLWRFTTTEVELAGVRLPARTPLLVDILGINTDPARTSGTDLTFGSGAHFCIGAQLAREELRAVVTVLRTDFPAARLAMPATEIRQVGPGGIMGSRLAMLPVALRG
>NZ_CP014859.1|WP_084642617.1|1275734_1277780_+|heavy-metal-translocating-P-type-ATPase
MHPQSHDHDHDGSHSVDRQHQHTGHAGHGSHAAAFRDRFWLSLALTIPVVLASHMIADLLGYTVPTWAGWVAPVLGTVVFLYGGQPFLTGAVGELRARTPGMMTLVALAITVAFVASALTTFGVAGLELDFWWELALLVVIMLLGHWLEMRALGQATGALDALAELLPDSAERIAEDGSISSVGLGELAVDDVVLVRSGGRVPADGVVTEGAAELDESMITGESNTVRRSVGDRVVAGTVATDSSIRVRVQAIGSDTALAGIARLVEQAQSSKSRAQALADRAAAALFWFALIVGALTFVVWLVIGDPTTAVERMVTVLVIACPHALGLAIPLVIAISTSMSAKAGILVTDRLALERMRTIDAVVFDKTGTLTKGRPVVTEVRAAPGGSRSEVLALAAAAEIDSEHPLAAAIVAAAREEGPIPEARDFRSLTGRGVQAVVDGATIAVGGPGLLAEREIRPPEDLAAETQSWAARGATVLHVLRDGVVLGAVALADEVRPESREAIEALHRHGVRVMMITGDARPVAEAVAADLDIDEVFAEVLPADKDSKVVELQERGRRVAMVGDGVNDAPALARAEVGIAIGAGTDVAIESAGVVLASDDPRGVLAVRRLSVAAHRKMWQNLAWATGYNLLTVPLAAGVLAGVGFVLPPAVGAVVMSLSTIVVAVNAQLLRRVKLTESA
>NZ_CP014859.1|WP_069847194.1|1275291_1275573_+|metal-sensitive-transcriptional-regulator
MRGYTEDKDGYLKRLRRIEGQIRGLQRMVEADEYCIDVLTQISAATKALQSVSIGLIDEHLKHCVAEAIAEGGEVANEKVREASEAVARLVRS
>NZ_CP014859.1|WP_069847192.1|1274382_1274988_+|TetR/AcrR-family-transcriptional-regulator
MADARALGLRADAARNYERIVVAAGQAFEEVGPAVTLEQVARQAGVGVATVYRRFRNRDQLVRAVVEHVITTEIQPVDIVASDDPWQDLTDFLNRSLDALTGRRVMIALARETDAIGPEAFAPFLRWMDELAGRLVDAGLVRPELVGQDLGAVIIMVLAMTQVRGESDSPARRRYLALLLDGLRPTSNVLPGVPLEPIMPC
>NZ_CP014859.1|WP_157421361.1|1273137_1274304_+|cytochrome-P450
MRRERFDPTAELGESRRAEGIRLVDTPFGESVHLVTRYEDVRMVLADTTRFGNDRAAALAGPAVEYTEEEARMRAGQLLALDPPDHTRIRRLLTPEFTMRRMRRLEPRIVEIVDAALDDLENAGRPADLVAHFGLPVPSLVICELLGVPYADRAEFQRRSDQMLDLSATDQQRKVAEDEIRLYLAELIARTMAAPNDDLLGMLVREHGTELTADELVGIATILLIAGHETTANMLSLGTLALLTHPEQLAMVRDDPAAVEPAIDELLRWLSIVHAGVARVAKTDTEVAGRSVKAGELLLMSLPGANRDPALREDPDRFDITRGVSGHVAFGHGVHHCIGAPLARMELRIGFPALLRRFPKLALAVPFEEVGFRSNHAIFGVNSLPITW
>NZ_CP014859.1|WP_069847189.1|1272753_1273014_+|helix-turn-helix-transcriptional-regulator
MGRREPGALSPRQQELLSLLVAGHSAESCARLMGIALGTVRNYIKDMWIELGLHGLAALIDWGIEHGYGTSGGKPDEPADGPTGQN
>NZ_CP014859.1|WP_069847187.1|1271414_1272521_+|winged-helix-DNA-binding-domain-containing-protein
MTVLDTRALNRATLARQLLLERSDLPVSDAIAHLGGLQAQEPQEPFIGLWSRLRDFDPTTLSDLLIGRTVVRTHLMRRTVHLLTAADTLAWRTRHNPMLRQRVLGVYRNELADVDLDELAAEGREVLADGEPRSMSELARAVAGRWPEPGPRPLGEMLVAALLPMVQLPPRGLWRTKAGVRNLLLSSWVGREIDPPAPEGTDPVGAALVRRYLAAFGPAASADLRAWCGLAGLPAAVASIRDELVTFRDERGRTLLDLRDAPRPDPGVPAPVRFLPAFDNAILGYHDRSRIIDDAHRGLSVAGIRVVLVDGRVAATWLVRDDTVSITPLRELAPTDRTAVAEEGEAVAAFLTDGDSSRIEITEVGADG
>NZ_CP014859.1|WP_069847201.1|1281731_1283657_-|M48-family-metalloprotease
MRGAVRAFLAVLLLILFPIFVLALGIGGTIAGINIGGRGGIYLAIVAVGLMLALGFGLVQALRTRLTPPDGPRLTRQEQPMLWQLVDELAANAQTRPPDEIILVPEINAAVQEDARGLGLQAGRRYMMIGLPLLAGLNVSELRSVLAHELGHYGGGHTRLLAITYRGAETLRRTVGRLDSGPARWILNGYARLYLMVSRSATRSQELQADAYSVAAAGRFTASEALRKIATMDMFWEAYADRFLNLPQLAQRTPDILLGFRFFLDAPENQRIRAEYEPKVLDAESSSVYDSHPTIRKRIAAIQNLPDNPAAPDQRPGWSVIMNPAQVLPAAEGVLYIRGEIGPKAGWDEIARLGCAELAAKNAARLAEAARQSGAAPSGALGEILNAVGRGEMVRLIAPLVREGIDPNEQIDAVRNLLTGLLGAVIVTALISQGRAHHELRWGGPAQVIGPNGPLDVAELVGPAVANPGLVPQFVARLQQLGVPLDFVRLPAPEAAAQQRPNDGQPQLMSVAPGIMAFRKTWDAFVTDIGLLLIPVKMSKLAGQNLSGMMGQGGQALNGRINTLLENGAAGLFARDDGRWVLNQNIVDGEHKKFLTGGGKIKLDFADGTKAEIRTDSDENFEVLLTYFSEVAAQSRQQAGG
>NZ_CP014859.1|WP_069847203.1|1284380_1284965_-|sugar-O-acetyltransferase
MTDAAHGAGDDTRSNREKMLAGEPYVFDAELAEHNDRAARLAARFGEIAPHDAAAGRAILEELLGAIGEETVIRGPLYVDYGSGLHIGARSFANFGLVALDVARITIGDDVQIGPNVQLLTPTHPVAPEPRRQKFESAEPITIGDNVWLGGGAIVLAGVTIGDNTVVGAGAVVTKDLPANVVAVGNPAKVVREI
>NZ_CP014859.1|WP_069847205.1|1285021_1285603_-|TetR/AcrR-family-transcriptional-regulator
MARTAGRQAGETKRLILAAATRLIGRHGTGVPLADIAEAAGVSKGGLLYHFPNKEELLNGLATDLMDRFRHDVEQAATEEAEGTPGRLTRAYIRVSFEHGGDDVELREHIALAVHLMFEPGLEELAQRDAQRWRTALLDDGLDQTISRMIIAATDGTNSAPLWGAVLSDADHVALQADLIALTHGRFPGLPGD
>NZ_CP014859.1|WP_157420969.1|1285635_1287138_-|MFS-transporter
MSEVLSPARRWASLAVLVGAVLLLAIDATVLYLAVPSLTAELSPTATQVLWIGDVYSLVLAGLLVTMGNLADRIGRKRLLLIGATAFGAASVLAAFAPSSEVLIVARLLLGVAGATIMPSTLSLIRNIFTEPIERTRAVAIWSAAAASGIALGPLVGGALLERFWWGSVFLINLPVMLLVLVVGGWLLPESRNPNPGRFDLISSGLSMLAIIPFVYTIKQLTSGSFGLGVVAAIVASVVGAVLFVHRQRRVAAPMIDVELFRNPAFSGAVLVNFISVFALSGVLFFFSQYLQLARGLGPLEAGVAQLPAALSAMAAVAAVGFLLTRLGRGRAIATALLIGAAGLGLLAALEGSEELIWVLLPMIPLGLGIGIAETLSVDAVVSSVRPTKAGAAASVAETAYELGVALGIAVLGSVITVLYRGNLDLPTEVAGEVAARAEDSLASATAILEPGSSALTAAQEAFMSAMQTTTLVAGAVMVVAAIVAFTLIPNDKAAVSTEH
>NZ_CP014859.1|WP_157421362.1|1287228_1287831_-|TetR-family-transcriptional-regulator
MSADERRRQLVGAALRVMKRDGIAAATTRAICTEAGMPHGAFHYCFHSKKELYAAVLASDIEIDLAAAWPRISAETSPAENIRTLLLAFWSQIEADPDSQLVLYDLGSFVLRDPELQELPRQQHLAGLERAIGYIRRLRDEASLTLLHEERLLAELTLATLNGVAWSWLAHRDNHAAREALSRFADLLATLVRSADDRAG
>NZ_CP014859.1|WP_069847208.1|1288059_1291167_+|cytochrome-P450
MTSQLAEDSPRIPGPAPLPVLGNLLEMLRAPQETSIELTADYHARYGGIFALDIVGNRQIFASDHRLVAEMCSSPLWSKSVHDALEQIRDFGGDGLFTAYSEEPNWGRAHRLLMPAFGTMAMKDYFPQMLDIAEQLMVRWQRFGSDHTIDVAEDMTRLTLDTIALCAFNVRFNSFYSEKPHPFVGAMVRSLVEAGARPERLPGVQPFLVGTNRQYRTDIAAMQRITDDIVATRNGLPAEDQPDDLLQRMLTAADPLTGEKLSEENIRHQLVTFLVAGHETTSGLLSFATHQLLANPDVLARAREVVDEVLGNRTPRFEDLADLGYLGQILRETLRLHPTAPAFALTPSEPTTLGGHRITPDDSVMVILPVLHQDPEVWPQPQRFDPDRFAPDRMDRIPEYAWMPFGHGARACIGRPFALQEATLVLAMMLQRFDIALADPDYRMTISETLTIKPKDLTIKARARSAAPQPRSEPATAAPHAPTAAEVRPSHGTPMLVLFGSNGGSSESLARTIAGDGHARGWNTEVAPLDDHAGTLPTEGPVVIVTSSYNGTPPDNARRFVDWLTESEPELTGVDYLVLGCGSLDWAATYQRIPTRIDEAMAAAGANRIRERGVTDARTDFFGDWERWYRPLWSELAARYGVADTAPTGPRYRITPTNAPRPERTDATAVVVQNRELTTGTRSKRHLELRLPEGRTYRTGDYLSVLPQNHPELVTRMLTRLGIDPEHLVSIASDAPNGRIPVGLPIRVDDLLTRHTDLSAPATPGVIAALAETTRCTPERRELTELANQAESGERRPSLLHLLERFASCPVDLAWVLERLPEPRARQYSISSAAEVQTEVALTVSVVEGPDRAGSGTYRGAASSYLQRTHPGDRLTVALAAPQEEFRPPADNSVPVVMIAAGSGIAPFRAFIAARRARAEKGEPHGANLLFFGCRHPDSDDLYAEEFAPLVAAGTLQVHRAFSRRPDGDVHYVQHRLWAERRSVLDLVEQGAHLYVCGDVTGMGPAVEECLRRIGPDEDWLDRLRAAGRYATDLF
>NZ_CP014859.1|WP_084642621.1|1291298_1293251_-|metallophosphoesterase
MDDPRRTDRDPAEAAASPAEATQAAGGPALGRRTLLHAAAAVPVIGAAASLPAVTAPAAHAQDEASTASAGRGADLESTRFVIAVLPDTQYLFDEDSSDPTPLRDAFRHVVDRRREEDIVFLAHLGDVTEHGSQHEIDLAERAFRFLDRKLPYSVLAGNHDVDGSTDDQRGDSPYLAAFGPDRFRRSSTYLGSSPGGYNSAHVLRAGDRDWLLLALDWRISDTGLDWARGVLAEHPTLPTILTTHDLAFASDDGIAQLSEHGRRLWDGLINDHDQIFLTLNGHYWPSGRTVLQNAAGNDVHVHIANYQDMYYGGAATLRYYSFDLVRGVIDVETFSPWLLGIDREDRSPLEAENVERTGEVDRFSVAIDFEKRFAGFSGVTPPAARPADEVVGRGTVAYWRFDESGLGETGADGNAVNEGTVARDLTGNGNDLVATRLHNGPADVLTFSADHHVDQPAHASLRFDGAKDPNRGALLRAVTEAPINSMTFESGYTIELFAKLPDPMVGDHSFMGLLSWEGRAGDAGKTSGWSQDEPTCSLNLSGERFLQYVVYPNDRDADPTSWSHALPMGRWMHLAVVNDGRQTVVYVDGSKIARNPTQRSKGITTLGKPFVIGGTQFAEEYSHGFYGWIGDVRISSRALRTTEFLTTRR
>NZ_CP014859.1|WP_069847209.1|1293487_1293685_-|hypothetical-protein
MTTITILGSGTVATALAGPLHAAGHQVIIDLGGVHTALGREAFLLMVRSLVGALGPVPFGMAVAR
>NZ_CP014859.1|WP_069847211.1|1293796_1294198_+|helix-turn-helix-transcriptional-regulator
MTTRTAAQAHTAARIAHREHCVRCPTNRMLDRIGEKWVALIIKELSGGLRRYGELGRAIPGASQKMLTQALRNLERDGLLTRTVTPEVPARVDYELTALGHSLLPVIQAVAQWADQHIEQIDSARAAHDARGR
>NZ_CP014859.1|WP_069847213.1|1294433_1295540_+|DNA-alkylation-repair-protein
MPFADELIGSNTVQVLTEAIETAAPDAPLIGLRAAEAQLGPLSLRERSDLLRYALLADLPGDYDSFAATIRRARDEATQFSGWLIWPVTSAVAAKAIDEGSAEAFDDALNLLGELTSLLSSEFAIRALLNHDLDRAMAKIYHWAGSSDVDLRRLASEGTRPFLPWAVRVPAILAEPQTTLPILDALYRDEAEYVRRSVANHLNDLSRQEPELVVATATAWLAEPDANTVHVVRHGLRSLIKKGHPEALSLLGFTPARLEVTGPIPATDSVTIGETLTFTASVRNLDTEPAQLAIDYIVHHQKASGVQTGKTFKLTTKTLEPGETYDITREHSFKVITTRRYHPGAHAVELQINGISSGRAEFTLLAED

Crispr_ID: NZ_CP014859_7

• CRISPR_ID: NZ_CP014859_7
• CRISPR_location: 1312441-1312592
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014859_7

Consensus_repeat	Method
TATCCGCCCCGCGCACGCGGGGGTGTTCCC	PILER-CR
ATCCGCCCCGCGCACGCGGGGGTGTTCC	CRISPRCasFinder

spacers of NZ_CP014859_7

>7.1|1312471|31|NZ_CP014859|PILER-CR
TGTGTGCTTCACGCTGCCACCTCTACGATAA
>7.2|1312532|31|NZ_CP014859|PILER-CR
GCCCCTTGACGGTCAGGTACCACGCCGACGG
>7.3|1312470|33|NZ_CP014859|CRISPRCasFinder
CTGTGTGCTTCACGCTGCCACCTCTACGATAAT
>7.4|1312531|33|NZ_CP014859|CRISPRCasFinder
TGCCCCTTGACGGTCAGGTACCACGCCGACGGG

CRISPR arrays and Neighbor proteins around NZ_CP014859_7

CRISPR arrays

The CRISPR arrays of NZ_CP014859_7

>merge|NZ_CP014859|7|1312441-1312592|PILER-CR,CRISPRCasFinder
TATCCGCCCCGCGCACGCGGGGGTGTTCCCTGTGTGCTTCACGCTGCCACCTCTACGATAATATCCGCCCCGCGCACGCGGGGGTGTTCCTGCCCCTTGACGGTCAGGTACCACGCCGACGGGATCCGCCCCGCGCACGCGGGGGTGTTCCC

>NZ_CP014859|7|5|1312441-1312592|PILER-CR
TATCCGCCCCGCGCACGCGGGGGTGTTCCC	TGTGTGCTTCACGCTGCCACCTCTACGATAA
TATCCGCCCCGCGCACGCGGGGGTGTTCCT	GCCCCTTGACGGTCAGGTACCACGCCGACGG
GATCCGCCCCGCGCACGCGGGGGTGTTCCC

>NZ_CP014859|7|7|1312442-1312591|CRISPRCasFinder
ATCCGCCCCGCGCACGCGGGGGTGTTCC	CTGTGTGCTTCACGCTGCCACCTCTACGATAAT
ATCCGCCCCGCGCACGCGGGGGTGTTCC	TGCCCCTTGACGGTCAGGTACCACGCCGACGGG
ATCCGCCCCGCGCACGCGGGGGTGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069847247.1|1309505_1309733_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847268.1|1320402_1321056_-|phosphonatase-like-hydrolase	unknown	unknown	gnl|CDD|274534
NZ_CP014859.1|WP_069847266.1|1319176_1320130_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270232
NZ_CP014859.1|WP_069847244.1|1308913_1309135_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847246.1|1309131_1309509_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847239.1|1307326_1307524_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069847241.1|1307670_1307865_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069847257.1|1315794_1316319_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|235811
NZ_CP014859.1|WP_069847251.1|1310471_1311200_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NZ_CP014859.1|WP_069847255.1|1314808_1315726_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|378820
NZ_CP014859.1|WP_069847269.1|1321247_1322009_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP014859.1|WP_069847259.1|1316649_1318362_-|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl|CDD|273441
NZ_CP014859.1|WP_084643571.1|1313246_1313876_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP014859.1|WP_084642624.1|1313905_1314769_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NZ_CP014859.1|WP_069853339.1|1312808_1313324_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_084643570.1|1306945_1307167_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069847264.1|1318391_1319180_-|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213223
NZ_CP014859.1|WP_069847253.1|1311338_1312259_+|virginiamycin-B-lyase	unknown	unknown	gnl|CDD|226708
NZ_CP014859.1|WP_069847249.1|1309836_1310430_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847242.1|1307861_1308728_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069847268.1|1320402_1321056_-|phosphonatase-like-hydrolase	gnl|CDD|274534	TIGR03351, PhnX-like, phosphonatase-like hydrolase. This clade of sequences are the closest homologs to the PhnX enzyme, phosphonoacetaldehyde (Pald) hydrolase (phosphonatase, TIGR01422). This phosphonatase-like enzyme and PhnX itself are members of the haloacid dehalogenase (HAD) superfamily (pfam00702) having a a number of distinctive features that set them apart from typical HAD enzymes. The typical HAD N-terminal motif DxDx(T/V) here is DxAGT and the usual conserved lysine prior to the C-terminal motif is instead an arginine. Also distinctive of phosphonatase, and particular to its bi-catalytic mechanism is a conserved lysine in the variable "cap" domain. This lysine forms a Schiff base with the aldehyde of phosphonoacetaldehyde, providing, through the resulting positive charge, a polarization of the C-P bond necesary for cleavage as well as a route to the initial product of cleavage, an ene-amine. The conservation of these elements in this phosphonatase-like enzyme suggests that the substrate is also, like Pald, a 2-oxo-ethylphosphonate. Despite this, the genomic context of members of this family are quite distinct from PhnX, which is almost invariably associated with the 2-aminoethylphosphonate transaminase PhnW (TIGR02326), the source of the substrate Pald. Members of this clade are never associated with PhnW, but rather associate with families of FAD-dependent oxidoreductases related to deaminating amino acid oxidases (pfam01266) as well as zinc-dependent dehydrogenases (pfam00107). Notably, family members from Arthrobacter aurescens TC1 and Nocardia farcinica IFM 10152 are adjacent to the PhnCDE ABC cassette phosphonates transporter (GenProp0236) typically found in association with the phosphonates C-P lyase system (GenProp0232). These observations suggest two possibilities. First, the substrate for this enzyme family is also Pald, the non-association with PhnW not withstanding. Alternatively, the substrate is something very closely related such as hydroxyphosphonoacetaldehyde (Hpald). Hpald could come from oxidative deamination of 1-hydroxy-2-aminoethylphosphonate (HAEP) by the associated oxidase. HAEP would not be a substrate for PhnW due to its high specificity for AEP. HAEP has been shown to be a constituent of the sphingophosphonolipid of Bacteriovorax stolpii, and presumably has other natural sources. If Hpald is the substrate, the product would be glycoaldehyde (hydroxyacetaldehyde), and the associated alcohol dehydrogenase may serve to convert this to glycol.	1.25588e-71
NZ_CP014859.1|WP_069847266.1|1319176_1320130_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	gnl|CDD|270232	cd01071, PBP2_PhnD_like, Substrate binding domain of phosphonate uptake system-like, a member of the type 2 periplasmic-binding fold superfamily. This family includes alkylphosphonate binding domain PhnD. These domains are found in PhnD-like proteins that are predicted to function as initial receptors in hypophosphite, phosphonate, or phosphate ABC transport in archaea and eubacteria. PhnD is the periplasmic binding component of an ABC-type phosphonate uptake system (PhnCDE) that recognizes and binds phosphonate. PhnD belongs to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. The PBP2 have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.73677e-73
NZ_CP014859.1|WP_069847251.1|1310471_1311200_+|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.35745e-27
NZ_CP014859.1|WP_069847242.1|1307861_1308728_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	2.46838e-09
NZ_CP014859.1|WP_069847257.1|1315794_1316319_+|helix-turn-helix-domain-containing-protein	gnl|CDD|235811	PRK06474, PRK06474, hypothetical protein; Provisional.	1.98749e-30
NZ_CP014859.1|WP_069847253.1|1311338_1312259_+|virginiamycin-B-lyase	gnl|CDD|226708	COG4257, Vgb, Streptogramin lyase [Defense mechanisms].	3.7329e-29
NZ_CP014859.1|WP_069847255.1|1314808_1315726_-|alpha/beta-fold-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	9.03544e-09
NZ_CP014859.1|WP_069847269.1|1321247_1322009_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.28666e-49
NZ_CP014859.1|WP_069847259.1|1316649_1318362_-|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	2.32814e-66
NZ_CP014859.1|WP_084643571.1|1313246_1313876_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.27416e-17
NZ_CP014859.1|WP_084642624.1|1313905_1314769_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	7.48258e-06
NZ_CP014859.1|WP_069847241.1|1307670_1307865_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.94147e-15
NZ_CP014859.1|WP_084643570.1|1306945_1307167_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.43907e-12
NZ_CP014859.1|WP_069847264.1|1318391_1319180_-|phosphonate-ABC-transporter-ATP-binding-protein	gnl|CDD|213223	cd03256, ABC_PhnC_transporter, ATP-binding cassette domain of the binding protein-dependent phosphonate transport system. Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	9.81913e-106
NZ_CP014859.1|WP_069847239.1|1307326_1307524_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.48962e-16

Protein sequences

>NZ_CP014859.1|WP_069847253.1|1311338_1312259_+|virginiamycin-B-lyase
MTNGPDVTIVAFPAGEPGEGPYATAAGPDGAMWFTHVHQGRIGRMALDGTQRTHALDSATAGPALIVAGPDDALWFTELHGNRIGRSTTDGDISEFELPTPDSAPYGLAVGPDDALWFTEMNTDRIGRITPAGEITEFALPDTGTFPSMIVAGPDGALWFTMNQANAIGRITTGGEVTVFPLPTEGAGPVGITRGSDDALWFVEIIAGQIGRITVDGAITEFPLPDRDARPHAITAGPDGACWFTEWGAGRAGRIDHEGAIRSYDLPADKPEPHGIALGADGGLWIALEAGAIARVTPSGERTSGR
>NZ_CP014859.1|WP_069847251.1|1310471_1311200_+|methyltransferase-domain-containing-protein
MTSIPESDQVNNYNSFAEIYNTENESSLENAYYERPATLRLAGDVAGRKILDAGCGAGPLSKELRDRGALVSGFDKSAGMLEIARKRLGDDVDLRVHDLAEPLPYADGEFDDVIASLSLHYLKDWGPTLAELRRVLRPGGRLIASVNHPTADYCIQRMSGHRPNYFEVYRDVGEFEMGGTTIQLAFWNRPLHKMTDDFTAAGFRIARISEPQPDEAGRELFPDVFYLLETAPSFLFFVLEAE
>NZ_CP014859.1|WP_069847249.1|1309836_1310430_+|hypothetical-protein
MTDRTPGDQHGSNAEPAIPASEPVVEPTANPDEPLRATDPLLIDQVTLPEVGIVCQRHAVFVDEGETLPSAGEQAFSLCGIPLTIGPPPAEMLPGVPAEVVDCADCQAIIWDEPAIEPVGSDFRLFVRRRGTIDVHIVEDSGLSATTMTARCGALFRLGEDLEQLAPGCGAPCNRCLLASLSGPATLPEHLAVSGEF
>NZ_CP014859.1|WP_069847247.1|1309505_1309733_+|hypothetical-protein
MRPVEWFVRAVRPGETHHGRADYRAESVVVSPMCGRSRFVALNRSPIHECYYDDQRCPDCLRLLASPALTLVRAS
>NZ_CP014859.1|WP_069847246.1|1309131_1309509_+|hypothetical-protein
MIVMGSVPAHWIHRCVRHAVRVAVGYEGRVLVFDGGRGTRSTVSTELARRDARLFLTTVEQRGMARLAAMRHTEPNQLQLRHVGHGLELSVLNRLGSLGRWVIEDRQLPELLRLVREAEFAARPS
>NZ_CP014859.1|WP_069847244.1|1308913_1309135_+|hypothetical-protein
MTALVLTGVLLVVFGAVLTVWSYRPVSPDPARHRRPRTVSAASILARCAAEAAAMQEEFRVGARTPLPAGGAR
>NZ_CP014859.1|WP_069847242.1|1307861_1308728_-|helix-turn-helix-domain-containing-protein
MNRTRNGAKSPRARALGSALAEARHAAGLTQRATASRLGVHHTRIARAETGAHPPSSEDTASILALFGITGAHRDEILEMARDIDRGNWTVTGAGVPSALTTLVDYEREATAITVSTPLLVPGLLQTMSYARAIISAGDATPEEIEARTMYRMGRQEILRAATAPRFMSIFHEWALQSPVGGHAAMAEQMKRLLSWIEHDHISVQVVPSSIGPSVSSSGNFSIYEFDRSPPIVHLEHLSASTFVDDARHIANFLAAREIVLKEAMSPEESIKLITDVYLPHHQERQDR
>NZ_CP014859.1|WP_069847241.1|1307670_1307865_-|DUF397-domain-containing-protein
MTSVRLQHWRKSSRSAQETDCIEIGDAPGIVGIRDTKNRDGGTLIVDRPAFDRFIAATKANRLA
>NZ_CP014859.1|WP_069847239.1|1307326_1307524_-|DUF397-domain-containing-protein
MTRHPQLAGWRKSSRSQNTTDCVEVGAAPGIVGIRDTKNRDGGTLIIGRPTFDRFIAATKANRLT
>NZ_CP014859.1|WP_084643570.1|1306945_1307167_-|DUF397-domain-containing-protein
MTTMNALRGWKKATRSAEATNCVEVGRASNQFGIRDTKNRDGGTLVIDRPTFNRFIAATKASQLTYQVKYAEA
>NZ_CP014859.1|WP_069853339.1|1312808_1313324_-|hypothetical-protein
MSTALRGEFRLALEVPGWAWRFYLRHFLPIVGLSLVASVQRLMVVNWAEQIPTAAVVASEILVLGARLLLFVVLWQLAMRNTAWHWDNLSEFARLHWPSLLIQGALLSVAFLVFDLLAENVVAGLLAEETRSTYLAVLLFVKNPTVIAFTFVWWVGLARQMLRTAPEKTPA
>NZ_CP014859.1|WP_084643571.1|1313246_1313876_+|MarR-family-transcriptional-regulator
MTQVEPPCPAGHLQRQPELTTQCRTHREPSHRSTNYFSVPKYLARYTDLVARGEDGDPGPALGRELSTAVVAFHEAVGSYLGVSAVDQRALGVIGAHGPLSAGALATLIGLTPGAVTGMVDRLERLDLVTKTPDPADRRRVVISVAGRGREGFGEIFGGLSTAMQAMVARYSPAEQELIADYVTRTIDILQEQTRELTRTTRRGSAGES
>NZ_CP014859.1|WP_084642624.1|1313905_1314769_-|CPBP-family-intramembrane-metalloprotease
MSTSASNTGKYSGDLVLFMAIAFVVSWALWGVAIAMGGPAVNPAATLPHLVGAFGPAIAALVIRIRRGRRGEPVPEHAVRSRFKTLGWVPVLMVLASATVLSGGLLAGVSGSAPMPSVDTAMAVLTAQSPVMFLAMMVISGPLAEEPGWRGTAYPRMRASMSRLQIGLVLGTIWAVWHLPLFFIAGTVQSQLGLATPSGVLFAVSSIPMAMLCCCAYERAGVVASVAVHFAVNLTMVLTNVQAPVTLALIMGIQAIVVAILLATGKDKAASGAPAATSDEPKVAENA
>NZ_CP014859.1|WP_069847255.1|1314808_1315726_-|alpha/beta-fold-hydrolase
MYDLDMTITADDGTALAGTLSLPIGPGPHPTVLLLHGSGPLDRDGNAAKLRSNIGPELATALAAKGIGMLRYDRRGAGATPGDWQRTGFYDNRRDAAAAITALAAHPDVRTDSIGVIGHSEGALHAMALAAQDEVRAVVLLAGFAGVGEDALRWQARSVIQGMPAPVRLLRRPAEALLNRVLNRLKNSTTDVVRIAGAPMNARWMREMLTHDTRKDLVAAKAEVLAITGDKDIQVDPADLIAIERLVPGAVEIHRSPDLTHILRRDSGTPSLRSYRRLFGEPVDPDLLSLVGTWLRERLTATPNA
>NZ_CP014859.1|WP_069847257.1|1315794_1316319_+|helix-turn-helix-domain-containing-protein
MATADLLLHPVRLRILQTLLGHDELTTAQLRERLPDIPAATMYRHVAALAQAEILEVVRERPVRGTVERSYRVRQEKARIEGDVRETMTKDDHRKAFAVFSGALIGDFDRYLSREDTEPAQENLLYRQGVVWVTDEEYTELVEELEAAVERRNEPGEGRTRHVISLVAVPDKPV
>NZ_CP014859.1|WP_069847259.1|1316649_1318362_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MPVPSVPSAPSATRLNTPPSAGAVAPTLVLLALLGLGVWAFADLRINVATFVDGAANAARFAARVFPLDFPPLLEILALCGQTLAIVVLATLLSALLSAPVALLAAADTTPNNAARMGARALIVVARAVPDVVLAIVFVRVFGIGSITGVLAMGLHSIGMVGKLYADAIEQSDPGPPTALRATGATRLQRITGAVLPQVLPAFVAVGLHRLDINLRVSVVLGFVGVGGIGFAIAESLRVLNYQRGIALALIVLALCIAVEVVSGAIRTALLGRAAAGPRRGITGALGRLVKPKQQVVVSADPRERSAAALAEGRVTPPWRMRRRGILYAVVSTVIVVASIAGAGISPLAFFEALPRIFEVLGQFLPPQTGGILPTLLAALWVTVKIALAATLIGVVLSIPIGALAAANVAPNARVARFFRLIILIIRGIPELILAIVFVVITGLGEVAGAVALGIGGIGLLGKLVADSLEEVDPGPERALRATGAGRLQVFLAATVPAAGKALVGHALYLLDTNIRSATLLGIVGAGGIGFYLLNAARVLDFGVVTTVLILIFATVMLVELLAMWLRSRW
>NZ_CP014859.1|WP_069847264.1|1318391_1319180_-|phosphonate-ABC-transporter-ATP-binding-protein
MSAAAEPAVVLDGVTRRFGADVLALDEVSLTVAPGEVVVLLGLSGSGKSTLLRHVDGLQQPSSGTVRTLGTDVGVARGGRLRELRRRVGFVFQQFDLVGSRTVLENVCTGALGRLRGPRLGLGTYPRALRREALAHLDRVGLADRAFQRADTLSGGQQQRVAVARALMQQPEILLADEPVASLDPESAHQVMELLRTISRENSLTVLCSLHQVDLALNWGDRLVGLRNGRVVLDLPTSGLDRDQVMSVYSRVGADAGLSPTA
>NZ_CP014859.1|WP_069847266.1|1319176_1320130_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein
MKHLTRSRRAATAAAAFLAAAAVTGCGASAVSDDPAGNPADPDTLVFAAVPAEESSSLQQSYDAVIAMLEQETGKTIEFRQATDYAAVIEGQLAGQVHIAQYGPLSFVLAQSEGAQVSPVGAYVDAEGDDPGYVSYGFANPDAGIESIEDFAGRTVCFVEPNSTSGYLYPSAGLIEAGIDPEEDITAVYAGSHDAAVLEVAAGRCDAGFAFDSMVDNQLIDSGDIAPGDIEKVWKSPIIPGSPAAISDQLAPELRETLSTAFREKANSDYLLANGFCEGDCPIGDEDAWGYAAVDDSTYEPVREVCDVTQNQNCLEG
>NZ_CP014859.1|WP_069847268.1|1320402_1321056_-|phosphonatase-like-hydrolase
MIELVALDIAGTTVAEGGAVYRVLAEVVADHGTPAAPAEIQRWMGADKRAALAELTGDPDSTERLHDEFVARLRAAYVETPPKPVPGVPEALALLREKGIRVALTTGFDHQVTDPLLAAIGWRVGDQLDAVVCADDVAAGRPEPHMIRRAMELTGVTDPQRVLAAGDTVLDIRAGRAAEAALVVGVLSGAQSRSELEPENPTEILADVSEIPALLQL
>NZ_CP014859.1|WP_069847269.1|1321247_1322009_+|GntR-family-transcriptional-regulator
MATPLHRIVAAELRNRIRSGRIGVGEALPAEAELCREFAASRGPVRQALAALREEGLIGGGGQGRRSVVLDAVPAQPFESFLSFTRRAELTGHVPGQRLQEIALRRPEPVVAAALQLEPDTLAVQLIRLRLLDGKPAMLERMSYVESVGRLLLNADLDAGSIYALLMDQGVELHTARHTFDAVPADSRDAELLGVALGHPLLRERRLTTDSRGMPLEWSDDRYRSDIATVTVTNTRNGRSGTGEPATVSPPVS

Crispr_ID: NZ_CP014859_8

• CRISPR_ID: NZ_CP014859_8
• CRISPR_location: 1316441-1316647
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP014859_8

Consensus_repeat	Method
ATCCGCCCCGCGCACGCGGGGGTGTTTC	PILER-CR
ATCCGCCCCGCGCACGCGGGGGTGTTTC	CRISPRCasFinder
ATCCGCCCCGCGCACGCGGGGGTGTTTC	CRT

spacers of NZ_CP014859_8

>8.1|1316469|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CCCGGCGGCGGTGATCCTGCGGTGCAACGCGAA
>8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
TGCTTCCGCTCGGTCGGGCTCGACCATCACGCC
>8.3|1316591|29|NZ_CP014859|CRT
GCAGCAAGCCGCCGATCGTCGCCTCCAGG

CRISPR arrays and Neighbor proteins around NZ_CP014859_8

CRISPR arrays

The CRISPR arrays of NZ_CP014859_8

>merge|NZ_CP014859|8|1316441-1316647|PILER-CR,CRISPRCasFinder,CRT
ATCCGCCCCGCGCACGCGGGGGTGTTTCCCCGGCGGCGGTGATCCTGCGGTGCAACGCGAAATCCGCCCCGCGCACGCGGGGGTGTTTCTGCTTCCGCTCGGTCGGGCTCGACCATCACGCCATCCGCCCCGCGCACGCGGGGGTGTTTCGCAGCAAGCCGCCGATCGTCGCCTCCAGGAAGCGCCCCGCCCATGCGAGGCGCCTCC

>NZ_CP014859|8|6|1316441-1316590|PILER-CR
ATCCGCCCCGCGCACGCGGGGGTGTTTC	CCCGGCGGCGGTGATCCTGCGGTGCAACGCGAA
ATCCGCCCCGCGCACGCGGGGGTGTTTC	TGCTTCCGCTCGGTCGGGCTCGACCATCACGCC
ATCCGCCCCGCGCACGCGGGGGTGTTTC

>NZ_CP014859|8|8|1316441-1316590|CRISPRCasFinder
ATCCGCCCCGCGCACGCGGGGGTGTTTC	CCCGGCGGCGGTGATCCTGCGGTGCAACGCGAA
ATCCGCCCCGCGCACGCGGGGGTGTTTC	TGCTTCCGCTCGGTCGGGCTCGACCATCACGCC
ATCCGCCCCGCGCACGCGGGGGTGTTTC

>NZ_CP014859|8|4|1316441-1316647|CRT
ATCCGCCCCGCGCACGCGGGGGTGTTTC	CCCGGCGGCGGTGATCCTGCGGTGCAACGCGAA
ATCCGCCCCGCGCACGCGGGGGTGTTTC	TGCTTCCGCTCGGTCGGGCTCGACCATCACGCC
ATCCGCCCCGCGCACGCGGGGGTGTTTC	GCAGCAAGCCGCCGATCGTCGCCTCCAGG
AAGCGCCCCGCCCATGCGAGGCGCCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069847247.1|1309505_1309733_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847268.1|1320402_1321056_-|phosphonatase-like-hydrolase	unknown	unknown	gnl|CDD|274534
NZ_CP014859.1|WP_084642625.1|1322019_1323150_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176193
NZ_CP014859.1|WP_069847246.1|1309131_1309509_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847266.1|1319176_1320130_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270232
NZ_CP014859.1|WP_157420971.1|1327606_1330021_+|penicillin-acylase-family-protein	unknown	unknown	gnl|CDD|376618
NZ_CP014859.1|WP_069847257.1|1315794_1316319_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|235811
NZ_CP014859.1|WP_069847271.1|1323294_1324419_-|TIGR03364-family-FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|132407
NZ_CP014859.1|WP_069847253.1|1311338_1312259_+|virginiamycin-B-lyase	unknown	unknown	gnl|CDD|226708
NZ_CP014859.1|WP_069847255.1|1314808_1315726_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|378820
NZ_CP014859.1|WP_069847273.1|1324673_1325849_-|glycosyl-hydrolase	unknown	unknown	gnl|CDD|185755
NZ_CP014859.1|WP_069847259.1|1316649_1318362_-|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl|CDD|273441
NZ_CP014859.1|WP_084643571.1|1313246_1313876_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP014859.1|WP_084642624.1|1313905_1314769_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NZ_CP014859.1|WP_069853339.1|1312808_1313324_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847269.1|1321247_1322009_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP014859.1|WP_069847264.1|1318391_1319180_-|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213223
NZ_CP014859.1|WP_069847249.1|1309836_1310430_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069847251.1|1310471_1311200_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NZ_CP014859.1|WP_069847275.1|1326420_1327371_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|181818

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069847268.1|1320402_1321056_-|phosphonatase-like-hydrolase	gnl|CDD|274534	TIGR03351, PhnX-like, phosphonatase-like hydrolase. This clade of sequences are the closest homologs to the PhnX enzyme, phosphonoacetaldehyde (Pald) hydrolase (phosphonatase, TIGR01422). This phosphonatase-like enzyme and PhnX itself are members of the haloacid dehalogenase (HAD) superfamily (pfam00702) having a a number of distinctive features that set them apart from typical HAD enzymes. The typical HAD N-terminal motif DxDx(T/V) here is DxAGT and the usual conserved lysine prior to the C-terminal motif is instead an arginine. Also distinctive of phosphonatase, and particular to its bi-catalytic mechanism is a conserved lysine in the variable "cap" domain. This lysine forms a Schiff base with the aldehyde of phosphonoacetaldehyde, providing, through the resulting positive charge, a polarization of the C-P bond necesary for cleavage as well as a route to the initial product of cleavage, an ene-amine. The conservation of these elements in this phosphonatase-like enzyme suggests that the substrate is also, like Pald, a 2-oxo-ethylphosphonate. Despite this, the genomic context of members of this family are quite distinct from PhnX, which is almost invariably associated with the 2-aminoethylphosphonate transaminase PhnW (TIGR02326), the source of the substrate Pald. Members of this clade are never associated with PhnW, but rather associate with families of FAD-dependent oxidoreductases related to deaminating amino acid oxidases (pfam01266) as well as zinc-dependent dehydrogenases (pfam00107). Notably, family members from Arthrobacter aurescens TC1 and Nocardia farcinica IFM 10152 are adjacent to the PhnCDE ABC cassette phosphonates transporter (GenProp0236) typically found in association with the phosphonates C-P lyase system (GenProp0232). These observations suggest two possibilities. First, the substrate for this enzyme family is also Pald, the non-association with PhnW not withstanding. Alternatively, the substrate is something very closely related such as hydroxyphosphonoacetaldehyde (Hpald). Hpald could come from oxidative deamination of 1-hydroxy-2-aminoethylphosphonate (HAEP) by the associated oxidase. HAEP would not be a substrate for PhnW due to its high specificity for AEP. HAEP has been shown to be a constituent of the sphingophosphonolipid of Bacteriovorax stolpii, and presumably has other natural sources. If Hpald is the substrate, the product would be glycoaldehyde (hydroxyacetaldehyde), and the associated alcohol dehydrogenase may serve to convert this to glycol.	1.25588e-71
NZ_CP014859.1|WP_084642625.1|1322019_1323150_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176193	cd08231, MDR_TM0436_like, Hypothetical enzyme TM0436 resembles the zinc-dependent alcohol dehydrogenases (ADH). This group contains the hypothetical TM0436 alcohol dehydrogenase from Thermotoga maritima, proteins annotated as 5-exo-alcohol dehydrogenase, and other members of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. MDR, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	4.26281e-124
NZ_CP014859.1|WP_157420971.1|1327606_1330021_+|penicillin-acylase-family-protein	gnl|CDD|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	7.82668e-110
NZ_CP014859.1|WP_069847257.1|1315794_1316319_+|helix-turn-helix-domain-containing-protein	gnl|CDD|235811	PRK06474, PRK06474, hypothetical protein; Provisional.	1.98749e-30
NZ_CP014859.1|WP_069847271.1|1323294_1324419_-|TIGR03364-family-FAD-dependent-oxidoreductase	gnl|CDD|132407	TIGR03364, putative_secreted_oxidoreductase, FAD dependent oxidoreductase TIGR03364. This clade of FAD dependent oxidoreductases (members of the pfam01266 family) is syntenically associated with a family of proposed phosphonatase-like enzymes (TIGR03351) and is also found (less frequently) in association with phosphonate transporter components. A likely role for this enzyme involves the oxidative deamination of an aminophosphonate differring slightly from 2-aminoethylphosphonate, possibly 1-hydroxy-2-aminoethylphosphonate (see the comments for TIGR03351). Many members of the larger FAD dependent oxidoreductase family act as amino acid oxidative deaminases.	5.67605e-136
NZ_CP014859.1|WP_069847253.1|1311338_1312259_+|virginiamycin-B-lyase	gnl|CDD|226708	COG4257, Vgb, Streptogramin lyase [Defense mechanisms].	3.7329e-29
NZ_CP014859.1|WP_069847255.1|1314808_1315726_-|alpha/beta-fold-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	9.03544e-09
NZ_CP014859.1|WP_069847273.1|1324673_1325849_-|glycosyl-hydrolase	gnl|CDD|185755	cd09216, GH64-LPHase-like, glycoside hydrolase family 64: laminaripentaose-producing, beta-1,3-glucanase (LPHase)-like. This subfamily is represented by the laminaripentaose-producing, beta-1,3-glucanase (LPHase) of Streptomyces matensis and related bacterial and ascomycete proteins. LPHase is a member of glycoside hydrolase family 64 (GH64), it is an inverting enzyme involved in the cleavage of long-chain polysaccharide beta-1,3-glucans, into specific pentasaccharide oligomers. LPHase is a two-domain crescent fold structure: one domain is composed of 10 beta-strands, eight coming from the N-terminus of the protein and two from the C-terminal region, and the protein has a second inserted domain; this cd includes both domains. This protein has an electronegative, substrate-binding cleft, and conserved Glu and Asp residues involved in the cleavage of the beta-1,3-glucan, laminarin, a plant and fungal cell wall component. Among bacteria, many beta-1,3-glucanases are implicated in fungal cell wall degradation. Also included in this family is GluB , the beta-1,3-glucanase B from Lysobacter enzymogenes Strain N4-7. Recombinant GluB demonstrated higher relative activity toward the branched-chain beta-1,3 glucan substrate zymosan A than toward linear beta-1,3 glucan substrates. Sometimes these two domains are found associated with other domains such as in the Catenulispora acidiphila DSM 44928 carbohydrate binding family 6 protein in which they are positioned N-terminal of a carbohydrate binding module, family 6 (CBM_6) domain. In the Cellulosimicrobium cellulans, glucan endo-1,3-beta-glucosidase, they are positioned N-terminal of a RICIN, carbohydrate-binding domain.	4.46299e-160
NZ_CP014859.1|WP_069847259.1|1316649_1318362_-|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	2.32814e-66
NZ_CP014859.1|WP_084643571.1|1313246_1313876_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.27416e-17
NZ_CP014859.1|WP_084642624.1|1313905_1314769_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	7.48258e-06
NZ_CP014859.1|WP_069847264.1|1318391_1319180_-|phosphonate-ABC-transporter-ATP-binding-protein	gnl|CDD|213223	cd03256, ABC_PhnC_transporter, ATP-binding cassette domain of the binding protein-dependent phosphonate transport system. Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	9.81913e-106
NZ_CP014859.1|WP_069847269.1|1321247_1322009_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.28666e-49
NZ_CP014859.1|WP_069847266.1|1319176_1320130_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	gnl|CDD|270232	cd01071, PBP2_PhnD_like, Substrate binding domain of phosphonate uptake system-like, a member of the type 2 periplasmic-binding fold superfamily. This family includes alkylphosphonate binding domain PhnD. These domains are found in PhnD-like proteins that are predicted to function as initial receptors in hypophosphite, phosphonate, or phosphate ABC transport in archaea and eubacteria. PhnD is the periplasmic binding component of an ABC-type phosphonate uptake system (PhnCDE) that recognizes and binds phosphonate. PhnD belongs to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. The PBP2 have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.73677e-73
NZ_CP014859.1|WP_069847251.1|1310471_1311200_+|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.35745e-27
NZ_CP014859.1|WP_069847275.1|1326420_1327371_+|helix-turn-helix-domain-containing-protein	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	1.0461e-109

Protein sequences

>NZ_CP014859.1|WP_069847257.1|1315794_1316319_+|helix-turn-helix-domain-containing-protein
MATADLLLHPVRLRILQTLLGHDELTTAQLRERLPDIPAATMYRHVAALAQAEILEVVRERPVRGTVERSYRVRQEKARIEGDVRETMTKDDHRKAFAVFSGALIGDFDRYLSREDTEPAQENLLYRQGVVWVTDEEYTELVEELEAAVERRNEPGEGRTRHVISLVAVPDKPV
>NZ_CP014859.1|WP_069847255.1|1314808_1315726_-|alpha/beta-fold-hydrolase
MYDLDMTITADDGTALAGTLSLPIGPGPHPTVLLLHGSGPLDRDGNAAKLRSNIGPELATALAAKGIGMLRYDRRGAGATPGDWQRTGFYDNRRDAAAAITALAAHPDVRTDSIGVIGHSEGALHAMALAAQDEVRAVVLLAGFAGVGEDALRWQARSVIQGMPAPVRLLRRPAEALLNRVLNRLKNSTTDVVRIAGAPMNARWMREMLTHDTRKDLVAAKAEVLAITGDKDIQVDPADLIAIERLVPGAVEIHRSPDLTHILRRDSGTPSLRSYRRLFGEPVDPDLLSLVGTWLRERLTATPNA
>NZ_CP014859.1|WP_084642624.1|1313905_1314769_-|CPBP-family-intramembrane-metalloprotease
MSTSASNTGKYSGDLVLFMAIAFVVSWALWGVAIAMGGPAVNPAATLPHLVGAFGPAIAALVIRIRRGRRGEPVPEHAVRSRFKTLGWVPVLMVLASATVLSGGLLAGVSGSAPMPSVDTAMAVLTAQSPVMFLAMMVISGPLAEEPGWRGTAYPRMRASMSRLQIGLVLGTIWAVWHLPLFFIAGTVQSQLGLATPSGVLFAVSSIPMAMLCCCAYERAGVVASVAVHFAVNLTMVLTNVQAPVTLALIMGIQAIVVAILLATGKDKAASGAPAATSDEPKVAENA
>NZ_CP014859.1|WP_084643571.1|1313246_1313876_+|MarR-family-transcriptional-regulator
MTQVEPPCPAGHLQRQPELTTQCRTHREPSHRSTNYFSVPKYLARYTDLVARGEDGDPGPALGRELSTAVVAFHEAVGSYLGVSAVDQRALGVIGAHGPLSAGALATLIGLTPGAVTGMVDRLERLDLVTKTPDPADRRRVVISVAGRGREGFGEIFGGLSTAMQAMVARYSPAEQELIADYVTRTIDILQEQTRELTRTTRRGSAGES
>NZ_CP014859.1|WP_069853339.1|1312808_1313324_-|hypothetical-protein
MSTALRGEFRLALEVPGWAWRFYLRHFLPIVGLSLVASVQRLMVVNWAEQIPTAAVVASEILVLGARLLLFVVLWQLAMRNTAWHWDNLSEFARLHWPSLLIQGALLSVAFLVFDLLAENVVAGLLAEETRSTYLAVLLFVKNPTVIAFTFVWWVGLARQMLRTAPEKTPA
>NZ_CP014859.1|WP_069847253.1|1311338_1312259_+|virginiamycin-B-lyase
MTNGPDVTIVAFPAGEPGEGPYATAAGPDGAMWFTHVHQGRIGRMALDGTQRTHALDSATAGPALIVAGPDDALWFTELHGNRIGRSTTDGDISEFELPTPDSAPYGLAVGPDDALWFTEMNTDRIGRITPAGEITEFALPDTGTFPSMIVAGPDGALWFTMNQANAIGRITTGGEVTVFPLPTEGAGPVGITRGSDDALWFVEIIAGQIGRITVDGAITEFPLPDRDARPHAITAGPDGACWFTEWGAGRAGRIDHEGAIRSYDLPADKPEPHGIALGADGGLWIALEAGAIARVTPSGERTSGR
>NZ_CP014859.1|WP_069847251.1|1310471_1311200_+|methyltransferase-domain-containing-protein
MTSIPESDQVNNYNSFAEIYNTENESSLENAYYERPATLRLAGDVAGRKILDAGCGAGPLSKELRDRGALVSGFDKSAGMLEIARKRLGDDVDLRVHDLAEPLPYADGEFDDVIASLSLHYLKDWGPTLAELRRVLRPGGRLIASVNHPTADYCIQRMSGHRPNYFEVYRDVGEFEMGGTTIQLAFWNRPLHKMTDDFTAAGFRIARISEPQPDEAGRELFPDVFYLLETAPSFLFFVLEAE
>NZ_CP014859.1|WP_069847249.1|1309836_1310430_+|hypothetical-protein
MTDRTPGDQHGSNAEPAIPASEPVVEPTANPDEPLRATDPLLIDQVTLPEVGIVCQRHAVFVDEGETLPSAGEQAFSLCGIPLTIGPPPAEMLPGVPAEVVDCADCQAIIWDEPAIEPVGSDFRLFVRRRGTIDVHIVEDSGLSATTMTARCGALFRLGEDLEQLAPGCGAPCNRCLLASLSGPATLPEHLAVSGEF
>NZ_CP014859.1|WP_069847247.1|1309505_1309733_+|hypothetical-protein
MRPVEWFVRAVRPGETHHGRADYRAESVVVSPMCGRSRFVALNRSPIHECYYDDQRCPDCLRLLASPALTLVRAS
>NZ_CP014859.1|WP_069847246.1|1309131_1309509_+|hypothetical-protein
MIVMGSVPAHWIHRCVRHAVRVAVGYEGRVLVFDGGRGTRSTVSTELARRDARLFLTTVEQRGMARLAAMRHTEPNQLQLRHVGHGLELSVLNRLGSLGRWVIEDRQLPELLRLVREAEFAARPS
>NZ_CP014859.1|WP_069847259.1|1316649_1318362_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MPVPSVPSAPSATRLNTPPSAGAVAPTLVLLALLGLGVWAFADLRINVATFVDGAANAARFAARVFPLDFPPLLEILALCGQTLAIVVLATLLSALLSAPVALLAAADTTPNNAARMGARALIVVARAVPDVVLAIVFVRVFGIGSITGVLAMGLHSIGMVGKLYADAIEQSDPGPPTALRATGATRLQRITGAVLPQVLPAFVAVGLHRLDINLRVSVVLGFVGVGGIGFAIAESLRVLNYQRGIALALIVLALCIAVEVVSGAIRTALLGRAAAGPRRGITGALGRLVKPKQQVVVSADPRERSAAALAEGRVTPPWRMRRRGILYAVVSTVIVVASIAGAGISPLAFFEALPRIFEVLGQFLPPQTGGILPTLLAALWVTVKIALAATLIGVVLSIPIGALAAANVAPNARVARFFRLIILIIRGIPELILAIVFVVITGLGEVAGAVALGIGGIGLLGKLVADSLEEVDPGPERALRATGAGRLQVFLAATVPAAGKALVGHALYLLDTNIRSATLLGIVGAGGIGFYLLNAARVLDFGVVTTVLILIFATVMLVELLAMWLRSRW
>NZ_CP014859.1|WP_069847264.1|1318391_1319180_-|phosphonate-ABC-transporter-ATP-binding-protein
MSAAAEPAVVLDGVTRRFGADVLALDEVSLTVAPGEVVVLLGLSGSGKSTLLRHVDGLQQPSSGTVRTLGTDVGVARGGRLRELRRRVGFVFQQFDLVGSRTVLENVCTGALGRLRGPRLGLGTYPRALRREALAHLDRVGLADRAFQRADTLSGGQQQRVAVARALMQQPEILLADEPVASLDPESAHQVMELLRTISRENSLTVLCSLHQVDLALNWGDRLVGLRNGRVVLDLPTSGLDRDQVMSVYSRVGADAGLSPTA
>NZ_CP014859.1|WP_069847266.1|1319176_1320130_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein
MKHLTRSRRAATAAAAFLAAAAVTGCGASAVSDDPAGNPADPDTLVFAAVPAEESSSLQQSYDAVIAMLEQETGKTIEFRQATDYAAVIEGQLAGQVHIAQYGPLSFVLAQSEGAQVSPVGAYVDAEGDDPGYVSYGFANPDAGIESIEDFAGRTVCFVEPNSTSGYLYPSAGLIEAGIDPEEDITAVYAGSHDAAVLEVAAGRCDAGFAFDSMVDNQLIDSGDIAPGDIEKVWKSPIIPGSPAAISDQLAPELRETLSTAFREKANSDYLLANGFCEGDCPIGDEDAWGYAAVDDSTYEPVREVCDVTQNQNCLEG
>NZ_CP014859.1|WP_069847268.1|1320402_1321056_-|phosphonatase-like-hydrolase
MIELVALDIAGTTVAEGGAVYRVLAEVVADHGTPAAPAEIQRWMGADKRAALAELTGDPDSTERLHDEFVARLRAAYVETPPKPVPGVPEALALLREKGIRVALTTGFDHQVTDPLLAAIGWRVGDQLDAVVCADDVAAGRPEPHMIRRAMELTGVTDPQRVLAAGDTVLDIRAGRAAEAALVVGVLSGAQSRSELEPENPTEILADVSEIPALLQL
>NZ_CP014859.1|WP_069847269.1|1321247_1322009_+|GntR-family-transcriptional-regulator
MATPLHRIVAAELRNRIRSGRIGVGEALPAEAELCREFAASRGPVRQALAALREEGLIGGGGQGRRSVVLDAVPAQPFESFLSFTRRAELTGHVPGQRLQEIALRRPEPVVAAALQLEPDTLAVQLIRLRLLDGKPAMLERMSYVESVGRLLLNADLDAGSIYALLMDQGVELHTARHTFDAVPADSRDAELLGVALGHPLLRERRLTTDSRGMPLEWSDDRYRSDIATVTVTNTRNGRSGTGEPATVSPPVS
>NZ_CP014859.1|WP_084642625.1|1322019_1323150_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MEQSQTADAGPRTPSIADGVGGPARYARWDGVGRGFTVVSTAAPRDLAPGEVLARVDLATVCGSDVHSVFGRRSSPAPGVLGHEQVGTVLAVGPGTPPLRVDGVPIEPGMRVVWSVAASCEQCDRCEADLPQKCRRLLKYGHEPLTDSWVLSGGFATHCVLQPGTAVVAVPAEVPDTVAAPASCATATVAAVLGAANRSLAGARVLVAGAGMLGLTAVAMAAQAGALVTAVDPDPARRASARRFGAADTREPGADQDADSDEFDIAVELSGSSESVRDCLDSLTVGGTLVLAGSVTPSPAVAVDPERVVRRLLTIVGVHNYRPADLQRAVDFLAAHHTAYPFTELVAGRYGLDELDAALASARDGGAPRRAVVPTL
>NZ_CP014859.1|WP_069847271.1|1323294_1324419_-|TIGR03364-family-FAD-dependent-oxidoreductase
MTSHSGLLDSVDLVVVGAGIVGLAHAYAAVERGLSVAVVERDERAVGASVRNFGHGCVTGQDGLALDYALAARHSWLRLATEAGFWLREAGTVVVARAEDEYRVLAEFAGLRDGQVQLLDAAGVRERVSTGPDVVGGALLPLDLRVDPREAVHAVARYLAERGVRFYFSTSAALIEPGEVVTSRGRVRAAHVVLAVGHDVDRFFPTLAEDHGLRRCALHMLRVADPHGREVSSAVLTGLSMLRYGGFAVCPSLTEVRDRITRESPRLLELGLNLMFTQLPGGDLTIGDTHSYARTHAPYQAEDLDECVLAEIAQLLGVPTLTVRERWRGIYASAPEPFLVAAPAPGVRVASVTTGIGMTTAFGFAPAVLDDLLG
>NZ_CP014859.1|WP_069847273.1|1324673_1325849_-|glycosyl-hydrolase
MATRRLFLGGLAASAIGGIALASELRRGVDTNAIGVRRLAVDAHTLPLTVVNNTGAYDNASIHMYIVGVDRITGNQARITPDGTIVAVSEADNGPDGWADYSIPLAGNGPTTINLSSMSGRVYFSMGEKLRFKVNPGNALVYPAGWVSADPNYRTLHDCMEFTFDDTGMYCNTTMVDMFSIPMEIQLTGEQSQTVGTLVDGGRAGIFNGMAQNSDYSQLVVDDLRVIAPGHGINSGQFSGSYFDPYIDEVWSKYAGETLTINANNRTFTGRVNGGIFEFDGGVAPISKPSTSDVFFCNGALHAPNDGVTGPVAAVLGAGLNRSTLHNTNVQPSTDPAAFYQTPVSNHYSRVLHENAVDGRSYGFPFDDVAEFASYVQDHAPTGITVTLTPF
>NZ_CP014859.1|WP_069847275.1|1326420_1327371_+|helix-turn-helix-domain-containing-protein
MHTVVVLAMDGVVPFDLSVPVEVFGRARLPDGRPAYRVRVCAETDEVPSGAFTLRVPWGLDALAEADTVILPGQDPVGELSDVVRQRLIDAAAKGTRIASICAGAFALAETGLLDGLRATTHWVATTELARRHPAILVDPNVLFVDNGQILTSAGAAAGLDMCLHLVRRDHGSAVAADAARQAVMPLERAGGQAQFIVREEPAPEGASLEPLLRWMTENAGTELSIDDIACHAAMSTRTLNRRFREQTGTTPLQWLHRVRLRQAQYLLETTDYSVERVAGQVGFGSTTTFRDRFKRLIGTSPNAYRRAFRTTEESP
>NZ_CP014859.1|WP_157420971.1|1327606_1330021_+|penicillin-acylase-family-protein
MNQHKSPPLGKHRRRLPILAMTATVAVLSGCFSSASDPAEAGGALAATIRYTEKGVPHVLADDHEDAGFGHGYAAARDHLCTIGTGMVTFAGERSRYFGPDETPAGALTTASTNLSSDLYYTSINQSGVIERLIDQPAPLGPSDEIRDLVRGYAQGYNLLLAERGGQACGDQGWLRPMTEIDVYRRAAAWSTFLGQTGVSDALAEGPAEETAESGGSSIPESTGPDLSKPGSNSIALGGDVTESGRGISVANPHLPWGGDFLFHQAHITIPGEWNANGASFIGLPTITIGHNASFAWSGTIADATRPFTLFELTLSPDDPTAYLVDDEAVPMERRAVTVDTRTPEGDIEPVTRTQWWTEFGPVITQLRDLPLPWSTETAFVLADPNTANMRLLDSFYAVSRATDIEEFDEALRAHQGISAFNLLGADSQGDTAYSGRTVLPNVTDAHAERCNTELGRATYQELGVAVLDAAQGDCAWPVDPAAVQPGAAGPGSLPYLERRDYLVNSNESYWLTNPEEPVTGFARLVGTTESTRSTRTRGAITEITDQLDTGDFTPDNTWDLVFSNRSHSAELALGGTVEMCASLPGGRARTSDGVFVDVTEACSALAAWDGRMDVDSRGAMLFSRYWLPLARTPDDVLWTVPFDPTDPVGTPNTLNPDNPALATALADAVADLDAAGIAVDAPLGENQYVEWDGERAAIGGGRGELGVFNVVASEWNPDAGHDAIGDGFGSNTSSYVHVVAFDGGECPDIRTLTTYSQSSDPDSPHFADQTQSFAEKQWITGRFCEADIQASPQLEVLEISNRP

Crispr_ID: NZ_CP014859_9

• CRISPR_ID: NZ_CP014859_9
• CRISPR_location: 2818581-2818678
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3,cas7,cas8c,cas5

Consensus repeat of NZ_CP014859_9

Consensus_repeat	Method
GGCACCGGCCCTTCGGGGCCGGTG	CRISPRCasFinder

spacers of NZ_CP014859_9

>9.1|2818605|50|NZ_CP014859|CRISPRCasFinder
AGGATCGAAACCACCAGCCGTACTTGGGCACCCGCGAATTCAGCGCCTGT

CRISPR arrays and Neighbor proteins around NZ_CP014859_9

CRISPR arrays

The CRISPR arrays of NZ_CP014859_9

>merge|NZ_CP014859|9|2818581-2818678|CRISPRCasFinder
GGCACCGGCCCTTCGGGGCCGGTGAGGATCGAAACCACCAGCCGTACTTGGGCACCCGCGAATTCAGCGCCTGTGGCACCGGTCCTTCGGGGCCGGTG

>NZ_CP014859|9|9|2818581-2818678|CRISPRCasFinder
GGCACCGGCCCTTCGGGGCCGGTG	AGGATCGAAACCACCAGCCGTACTTGGGCACCCGCGAATTCAGCGCCTGT
GGCACCGGTCCTTCGGGGCCGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069849172.1|2820609_2824083_-|ThuA-domain-containing-protein	unknown	unknown	gnl|CDD|377643
NZ_CP014859.1|WP_069849183.1|2830686_2831499_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NZ_CP014859.1|WP_069849166.1|2813487_2815305_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP014859.1|WP_069849155.1|2806441_2807881_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143465
NZ_CP014859.1|WP_069849164.1|2812798_2813488_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	gnl|CDD|187534
NZ_CP014859.1|WP_069849180.1|2828357_2829377_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|378117
NZ_CP014859.1|WP_069849162.1|2810494_2811712_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP014859.1|WP_069849178.1|2827519_2828344_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224041
NZ_CP014859.1|WP_069849170.1|2818738_2819512_-|META-domain-containing-protein	unknown	unknown	gnl|CDD|377111
NZ_CP014859.1|WP_069849176.1|2826065_2827226_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP014859.1|WP_069849182.1|2829417_2830293_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
NZ_CP014859.1|WP_157421053.1|2809488_2809845_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_084642961.1|2816270_2818472_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP014859.1|WP_069849153.1|2804951_2806433_+|FGGY-family-carbohydrate-kinase	unknown	unknown	gnl|CDD|198372
NZ_CP014859.1|WP_069849168.1|2815304_2816222_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl|CDD|377458
NZ_CP014859.1|WP_069849174.1|2824831_2826028_-|hypothetical-protein	unknown	unknown	gnl|CDD|271377
NZ_CP014859.1|WP_069853632.1|2807920_2808694_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NZ_CP014859.1|WP_157421054.1|2824363_2824765_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069849157.1|2808795_2809293_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069853634.1|2819638_2820511_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014859.1|WP_084642961.1|2816270_2818472_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	3.4e-46	152.5	0.0
NZ_CP014859.1|WP_069849166.1|2813487_2815305_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	6.4e-54	178.1	0.0
NZ_CP014859.1|WP_069849164.1|2812798_2813488_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	3e-56	185.1	0.0
NZ_CP014859.1|WP_069849168.1|2815304_2816222_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	2.1e-75	248.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069849183.1|2830686_2831499_-|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	3.36658e-77
NZ_CP014859.1|WP_069849166.1|2813487_2815305_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	9.6857e-50
NZ_CP014859.1|WP_069849155.1|2806441_2807881_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143465	cd07147, ALDH_F21_RNP123, Aldehyde dehydrogenase family 21A1-like. Aldehyde dehydrogenase ALDH21A1 (gene name RNP123) was first described in the moss Tortula ruralis and is believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and ALDH21A1 expression represents a unique stress tolerance mechanism. So far, of plants, only the bryophyte sequence has been observed, but similar protein sequences from bacteria and archaea are also present in this CD.	0
NZ_CP014859.1|WP_069849164.1|2812798_2813488_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.31575e-66
NZ_CP014859.1|WP_069849180.1|2828357_2829377_-|ABC-transporter-substrate-binding-protein	gnl|CDD|378117	pfam09084, NMT1, NMT1/THI5 like. This family contains the NMT1 and THI5 proteins. These proteins are proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine. They are regulated by thiamine. The protein adopts a fold related to the periplasmic binding protein (PBP) family. Both pyridoxal-5'-phosphate (PLP) and an iron atom are bound to the protein suggesting numerous residues of the active site necessary for HMP-P biosynthesis. The yeast protein is a dimer and, although exceptionally using PLP as a substrate, has notable similarities with enzymes dependent on this molecule as a cofactor.	2.96649e-41
NZ_CP014859.1|WP_069849162.1|2810494_2811712_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.33452e-08
NZ_CP014859.1|WP_069849178.1|2827519_2828344_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.33855e-119
NZ_CP014859.1|WP_069849170.1|2818738_2819512_-|META-domain-containing-protein	gnl|CDD|377111	pfam03724, META, META domain. Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.	7.45e-12
NZ_CP014859.1|WP_084642961.1|2816270_2818472_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	8.5804e-53
NZ_CP014859.1|WP_069849176.1|2826065_2827226_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.74797e-48
NZ_CP014859.1|WP_069849182.1|2829417_2830293_-|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.86618e-74
NZ_CP014859.1|WP_069849172.1|2820609_2824083_-|ThuA-domain-containing-protein	gnl|CDD|377643	pfam06283, ThuA, Trehalose utilisation. This family consists of several bacterial ThuA like proteins. ThuA appears to be involved in utilisation of trehalose. The thuA and thuB genes form part of the trehalose/sucrose transport operon thuEFGKAB, which is located on the pSymB megaplasmid. The thuA and thuB genes are induced in vitro by trehalose but not by sucrose and the extent of its induction depends on the concentration of trehalose available in the medium.	2.20238e-87
NZ_CP014859.1|WP_069849153.1|2804951_2806433_+|FGGY-family-carbohydrate-kinase	gnl|CDD|198372	cd07804, FGGY_XK_like_1, uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases. This subgroup is composed of uncharacterized bacterial and archaeal xylulose kinases-like proteins with similarity to bacterial D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17), which catalyze the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. The presence of Mg2+ or Mn2+ is required for catalytic activity. D-XK exists as a dimer with an active site that lies at the interface between the N- and C-terminal domains. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	2.90893e-81
NZ_CP014859.1|WP_069849168.1|2815304_2816222_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.18574e-97
NZ_CP014859.1|WP_069849174.1|2824831_2826028_-|hypothetical-protein	gnl|CDD|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	8.46634e-14
NZ_CP014859.1|WP_069853632.1|2807920_2808694_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.77273e-20
NZ_CP014859.1|WP_069853634.1|2819638_2820511_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	2.29427e-16

Protein sequences

>NZ_CP014859.1|WP_084642961.1|2816270_2818472_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYAHSKAGASVEHWHPFTDHAEGTALLARLFAEPLNAPDLGELLGLCHDAGKCFNDWQRRFLAVGGRGRRHGRVGIPHADVGAHLLRDAAGPAALAVLGHHKGLTTVAELADLPANPDQAARFAEAQRAFLRAVPRAEDLLNRRDLIPAEWRENRSLRDMGLRLVYSALVDADYLDTSAFMAPTEVRTGEDLTTVNLLARFDEARTSRALPISELNLLRDDIYEQAVQSAELPAGMYRLTAGTGTGKTLTSTGFALNHARKHGHRRVIMVVPFITITRQNAEVLKSKLGAESVLEHHSAVDLPNDSWTKLATENWDAPFIVTTTVQFFQSIFARRPGPMRKLHRIARSVIILDEVQALPATMLVPILDALRILVEHFGCTVLLCSATQPTFDRLPIWRKLTVKDIVTVPKTRLERARTVRFRYWSDPRPTWDEVAQDAATHDQALLIVNTRADARDLYSACQRAAPEHRVLHISRNMCDRHVMATFESAKKALGRNEKLLLVTTQLVEAGVDIDFPTVYRAWATAEAHLQSAGRCNREGNRSEGLVIIFDPAGGRLPAGYYRVGAEVARRHFGPAQANPDNLDALSEYFGEVFHYLKLDSQGFPRNKQKWEHWHHVTHNRSRLNFRDVADGVHRFQMIDEDSVPVVISSYRGPIGETALEHLAEIRAAVGNAASAAKPTRLREAIRALQPYTVSLSKSSVRRAEERGDLVPIITDVLYGWTGGYSQQTGIDI
>NZ_CP014859.1|WP_069849168.1|2815304_2816222_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTTAYSDPAVRHDMLLVFDVLDGNPNGDPDAANQPRQDLQTNQGLITDAAIKRKIRDTVPLLAAAASADPDRYRIFVEAGETLNPRLEESYTANNIPLEKAEGTGAKKTRKRIEVGQADEARAWLRNRYYDLRLFGGVLGTGNTQSLGKMRGPMQVTFGRSVDPIAPEQHAITRVAKTRAEDAGHGEMGNKWTVPYGLYTARIHYSAVRGKEAGVTADDLELFYRALLMMWDHTSSASRGEMATRGLYVFSHPDAYGVVPAHKLLDRIVVHRTRPDEPARSFAEHYKLDLDDSGLPAGVTVAQLA
>NZ_CP014859.1|WP_069849166.1|2813487_2815305_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLHHFAEQGALLNSGDAPRNYVERSVHWQLDLDGDGRVLGLTPLGLQGTRGTTHLIPDPSRSSEVAAGLGSDIGEYVLGWQRVDRKTKERIANAKTPSRQRAFRRLMEDWAAQTEPERDPVPHIVAGFLQSGIVVEQPVDADGSQYVMLTVRLAGRTIPVHESASAAEFWAAEIKRRKGGISAQGSDNTREGFCLICSQQRPLAMTVPGSIPRGLLPGATSSISVASVNGAAFGYDGALQLAHAPLCFPCADDIVNGAVHVLSHNRISWPGQHSVTTWWVSDSAAEQVAAAIMGTLLEEGSDDPDDVSEVLGSARDGMERRRSIATAHFRAATLGAYISRLVVRDWIDISLSELLANVRSWMTDHRVNGRVFSLRRLAVSCGRYTDKRYAQMGSKSDDRLADLQDILLHAALLGLPVPGKVANRVLHRIWRDHHIDGPRLALLQLTRRGQPVLTLDAPDQPAAYVLGRLIALFDSVQARSSDGKINRTFAARTLSSARARPGLVLRDGIQLAESAWLPKIDRSKPVSAMALRRELAAVQVLITDDTALDRPLSPSGQVLLVLGLGHQRHRLFERADEARARARARAREADPNIDSDDTDNSGEQ
>NZ_CP014859.1|WP_069849164.1|2812798_2813488_+|type-I-C-CRISPR-associated-protein-Cas5
MTAHRAMNSRGRVSMQVWGEAALFTRPEFKAERVTYPCLTPTAAVGVLESIYWHPGMRYEMDRIEVLKPIAQFAIRRNETSAVPSVRSALAGKILNTATPEARTQRMSLCLRDVGYRIHAWIQVLDGADKPLPAYRDQFNRRLRRGACFSQPYLGSREFVADFGVLDETPLQQNLDLDMGLMPHSADYDRAGKLVRWNWFSAELKGGVLDVPRQGLTPSSAESALEAAG
>NZ_CP014859.1|WP_069849162.1|2810494_2811712_+|helix-turn-helix-transcriptional-regulator
MQQGSESGVTLGTATRRLRRWRGMTVEQAAGLAGMSKGYWSKIENGYVTVERRSTLTKIANALRVSLSDLTGEQHLLAGSSDEVSGAIPDIRLALLQSSLDDASQECERSILALKSETTRLAVARQSAELATVGRAMPALLVDLHAVAASDGPARAEALRSLVLACQVTTMLVKNLGATDLAWIAAERGHEAAMRLDDPVWIAASEFARSQALIGLGAFARAEALARQAVEMLPNSVDSTELLELRGNTLLTSAFAGAVAETADPAAAITEATELAARTEASNAFFLAFSQANVDQWRISIAMETEDPILAAQVARDLDPERIPFASRRTGLLIDHARALAALRGHDLEVIELLQQAYRLAPTRTQHDIFVREIVTELLLRARRDAGGRDLRFLADRIGLLDPRR
>NZ_CP014859.1|WP_157421053.1|2809488_2809845_-|hypothetical-protein
MSAVRERPATRIKAVGGRAMNRDGERWFLQDALPRAGLCLDRHLIRGSRPAEGTDVITACGVSVVVSPSPDCDVDGDLALFSVRPCWLCVEQATGDSRPYARPRPDAEGMRSLRRNFD
>NZ_CP014859.1|WP_069849157.1|2808795_2809293_-|hypothetical-protein
MPRIHPSIPTRPAPTEQVPVILRASPGANEPWLVWEALLAAAQRWTVRPAEALRHAHGISVYDYRLLRLLARAPHPMRKAIVTTALDLPPRSLDHSVTRLAERGFLLVRGARTDRRLVLTPAGTQFLIEVVATLRSVTDTAVGADTALRPSERAALVALLARLRT
>NZ_CP014859.1|WP_069853632.1|2807920_2808694_-|MerR-family-transcriptional-regulator
MAWSTRQLAELAGTSLRAVRHYHTVGLLAEPERDSNGYKRYAVAHLVRLLRIKRLADLGFSLAQIANLADTDEHPEREMRALDAELAKNIERMQAVRAELAATLENSPPIDLPTTLGLSAEDVRFSEADRSFIVVLSRLVDPETLGPWAEMLTAAEDELSTLRSDADEDTRQRLAERLAEHLYDLMIAFPSMADLSEDSRLKKESSVQAIGAALVDLYNPAQIDVMVRMNIALAALREPATSDAATPDDDRPDTDGG
>NZ_CP014859.1|WP_069849155.1|2806441_2807881_+|aldehyde-dehydrogenase-family-protein
MDTIRPCWVAGRPVTGTETLPVYHPFDGAPVGVAAVPDTADVERAVAAAQAATAETAALPAYRRADALRAAAAGLRRRADEIAALITAESGKPLRWSRIEVTRAAGVLDWAAEEARRWSGELQRLDTDPGGVGRIAMTRRVPRGPVLGIAPFNFPLNLVVHKLAPALAVGAPIIVKPAPATPLTALLLGELLAEACLPEGSWSVLPVPDDRMPELVADPRLPVVSFTGSVPVGWRIRDAVPRKHVTLELGGNAAVIVCPDWSSEADLACAARRIAAFATYQAGQSCIAVQRVLVHRDLRERFTELLVAAVRALTLGDPADERTEVGPLINEPAARRVEDWITEAVAAGGRLLTGGARDGATLTPAIVADVPPGERLVAEEVFGPVLTVADFDEIDGAFAAVNESRFGLQAGVFTHDLRTAFRASEVLDMGGVVIGDVPSYRADQVSYGGVKDSGIGREGVRAAMDDLTQDRVLILSGLD
>NZ_CP014859.1|WP_069849153.1|2804951_2806433_+|FGGY-family-carbohydrate-kinase
MDARPVVCAVDVGTSAVRAAVVTADGRVLRQARRERPPGQGAVTFDALRLWADLQIVLRTLFAEGTEGDAASEDLRALAVAGHIGTVALDDTGEPVAPGGGWADTAGADEVTQGWADPAVALYRAGRPVVTGGAVPALRALRRTDPRAHQRIRCVSSPKDFLVGRLTGVAATDHTSAAYTLGSDVHRRTWSAELIAAADLDPTCFPPQHAATDLVGHVHADAARRTGLPEGLPVACGGPDGTVGAAAVLGSRTGAVVDVAGSTDVLTRILTDPAEAAGRAGVLNPYLDGAHWSLGGATGMTGAGVAHWTALLGLGDPATATAELGAAYDDIPPGCDGLALVPLVTGSRFPDWQPAERGALWGMHERHGPAHVVRAAQEAAAYVVRSAVEALGGTDDGVPVLLAGGTAKSPSLTQLRADVLGRPLSVCVEADVSLRGAALLATVAAGLHPDLRSAQAAMAPRLTGVEPDPERSHRYDELYRRWQRTRQAVIDTR
>NZ_CP014859.1|WP_069849170.1|2818738_2819512_-|META-domain-containing-protein
MRTRTFGTAIGGALLLFACVACGSDAPPTGPWQLAEGTTAEGAIPLDDAWPVTLRFEDGSIKGTAACNHYGTRASINGTSLRLAEGGLTNMYCPADDFEVMATESRYLEALWAANGIEQTSETFTLTGPDIELTFRPLTEPPVADLVGRTWVLDSLAGTEDGTSEPVGTPAELEITEDTLRADTGCGEFSGRWIIRGEQILVNYAASETPEECAEDVVDQHGHLINILGDGFRPDLDGDRLSLISAGGRAAEYRDAG
>NZ_CP014859.1|WP_069853634.1|2819638_2820511_-|sugar-phosphate-isomerase/epimerase
MGIVQPESRRGFLRLAVGSAVAVGASGLIAPNAVAAAAPGGNRPVPREHIGIQLYTVRSLMESDPQGTLNRLGEIGYATVGVSGLYGHSPQEFRAMLDAAGLRAVLTHLSLDAIRGDWQQALVDAHVLGVQSVVVPSLPSDLQNPAGYRQVAKEFNEAGRAARRSGLRFLYHNHGFDFATVDGQILYDILLQETKRQWVNFEIDLYWAVEGGYDPVDYFRRYPGRFPVFHVKDMAEDGSFEDVGHGILDFPRIFAERRSGVREYIVEHDAPADPLASAQRSYEYLSTMRF
>NZ_CP014859.1|WP_069849172.1|2820609_2824083_-|ThuA-domain-containing-protein
MRHPTRPHSGRRNRFAAALGGLLAMVLATTVAVPTAGATESRFTVLVFSKWTNFYHDSIPAGIEAIEELGAANDFDVEATDDASIFNDEDLDRFDAIVFNNTNSTPESGDLLDADQRAAFQRYIQDGGGWVGLHAASASERDWDWYEGLVGAIFDQHPEIQPGRVKVLDGAHPSTSELPELWERNEEWYNWTANPTGNVHTLAQIKVRDGIEGLDEGVDHPFSWCQNYDGGRSWFTAGGHASTDFSDELFLNHLLGGIEWAAGAAPGDCSATQTGNFQQIPLVTEGLADPFELAVAPDRRVFYIERTGALKIVDQETLAVSTALDFDYTAEMTSQSDGLLGLTLDPDFAENNFLYLLYSDKDEAKLNVSRFTVEGDSVDLATEARLLEIPTFRGEGRANSHMAGSLAIHDNGDLYIATGDNTDPFASDGFSPIDEREGRRAWDAQATAGNTNDLRGKILRITPQDDGSYTIPEDNLFAEGTELTRPEIYAMGMRNPFRITVDSKTDAVLVGDYGPDARAADPNRGPEGTVEFDRITEASNRGWPYCTGANTPFNDYDFATSTAGEPFDCANLVNDSPNNTGLTELPPAAPAWVHYAYSESEEFPELGTGGGGPMGGPVYSYDPDNERITKFPEYFDGKWFTYELTRQWFKTMSIHQTSQEFTDPRFEPTNEGDLHSINGIFEDMSWIQPFEAEFGPDGSLYVIDFGEGSGTGRGGSNEGSGIYRVDYVAEGRVPTAAISAGPDSGQGPLEVSFSSEGSGAGEDESVRYEWDFDNDGTIDSTEENPTHVYTENGQYSARLTVTNTETELAGVAVTTITVGNTRPEVRIDFPHHGGMFDFGDTIPFTVEVTDAEDTEIDCSRVVVQSQLGHDDHLHPMDNVTGCQGEFITDQGDSHGPGQNLFAALSAQYQDGGGTDDVPPLVGSAHATLEPKRKEAEHFEDTGGDNDGVQAVSREGSSAGRRIAEIEHGDWVAYDPINLTEIDSVTMGVSSGGIGGTVEFRADAPDGELLGSVEVGNTGGWDSVISPTVPLTDPGGPITLYAVFTNPEWAADGPDLMSVDWLHFNGQGVTKPEISATVEPVATPNTGAAPLTVDFSAEVTAPEGREIVDYHWEFGDNQSTHDETASHEYTRSGPFTARLTVTDDAGVRTSATVDVSVD
>NZ_CP014859.1|WP_157421054.1|2824363_2824765_+|hypothetical-protein
MVAPIPLASSVLLVADPSAIAVAPGANGVVADSSRQRFLDNPQAVAAKRVQVDRRTRARQWRTLIHPNNLFSYDAFTIDESTSNSWRQWPVRWDWDAGSEVGVIDIDIAPGSPISRLSNRFDKRSKNSAEAVL
>NZ_CP014859.1|WP_069849174.1|2824831_2826028_-|hypothetical-protein
MTAAAGPVPTGRRWPSAAGAWLGIGAAPGALVLGAQVAQRNDGALPLVVLLAGGLVMAALLAGQGMLGLLPPAGENSTLSAASARYLPPVADHAVALLMTLAMIGWFGFNVGLGGAALGALTGLPDWAAAIVLGLPLLGVIVAGGGRWNGLAIVATCSAIVLIGLVALRTAPSSVPVSLTSGGPRSMAVDLAGFLGYVSVFAMRAPDFTVGLRGRRDLAWCVALLVGPALAAAIVGAGLSASTGSSDVVATLAGPQGMAAANLFLAVAVVAPTLACIHSGSLALGRLARLPRLLLPWAVAIPGLVLAMLRVDRLMADWLVLLAAAVPALVVPMVWEAARRRRGGAPELISTWAWLPAAVIAVLGTLAGYPEAALAGLGLAVLAAMSAQWWRRRKAGDR
>NZ_CP014859.1|WP_069849176.1|2826065_2827226_-|Gfo/Idh/MocA-family-oxidoreductase
MSSTADRRIGIVMNGVTGRMGYRQHLVRSILAIRAEGGLLRADGTRLIPEPILVGRNAAKLEAMARDHGLERWTTDLDAALAEPDAEVYFDAQVTSGRAAAITAAIAAGLHIYTEKPVASDLTDALTLARTARDAGVKAGVVQDKLFLPGLRKLHRLVTGGYFGRILSVRGEFGYWVFEGDWQPAQRPSWNYREEDGGGIILDMFCHWRYVLEEIFAPVRSVQCLGATHIPQRFDEAGEPYAATADDAAYGTFELDGGIVAQINSSWTTRVFRDELVEFQVDGTEGSAVAGLRRCRVQHRSTTPKPVWNPDLPATEDFRAGWQEVPDNAEMDNGFKTQWELFLRHVVDDEPFPWDLLAGAKGVQLAELGLQSWAEGRRLAVPELTL
>NZ_CP014859.1|WP_069849178.1|2827519_2828344_-|ABC-transporter-ATP-binding-protein
MTESDTIGAIEPDRPHGSGSAVDLLDVAVRFRTKKRDVTALQEVSLQVAPEEFVAIVGPSGCGKSTLLKLVSGLLQPSSGDVRLLGDPVSKPRRDVGYVFQRAALLEWRSVRRNIALQAEMRKMPTAEAAARVDELIAMTGLRGFEDAYPHELSGGMQQRVSLCRALLHRPPVLLMDEPFGALDALTREQMNVELRRIRQETRTTVLLVTHSIAEAVYLADRVVVMTARPGTVAEIIDVDLPTERDYAETLTHPEFARASGRIRELLGAASAAE
>NZ_CP014859.1|WP_069849180.1|2828357_2829377_-|ABC-transporter-substrate-binding-protein
MKVSRVVVGATVMALAAGCGGTGGETTTNADGVELDVVTLTLNWYPYGEHAPFYHGLEQGVFEEHGIDLRIQAGQGSQKTVQATTSGQTDFGWADTPAVLAGVAQGLDVTSVGVFLQTTPSSAQFFSDKEIESPDDLRGMTIASTAGDALSATFPAFLEINGIEADEVELQNTDPAGKMAAVISGQTDALLGFATDQGPTMQESADRDVSYLRFADHGLNFFSNGLITASDNLTEREDLVRRMVTASSQAWAQAAEADPAEVVGAMSDAGEQLPSPEVLTEQFEATLELLHTEATEGMPPGVNTEEDWTTTIEIFAEAGVIETAEEPAAYWDASFAPEG
>NZ_CP014859.1|WP_069849182.1|2829417_2830293_-|ABC-transporter-permease
MTAQSTIDDTDATRSAVSGVAERGRPGIGERLTAFLDQAWRPVALLAALFLVWWAVTAAELVEPYLVPSPGDTLSAITERPEYFIDNTLVTTYETVLGFVIASIVGVLAAVVMVYSSTIEKTLYPLLLFAQVIPKIAIAPLFVVWLGFGLEPKVVVAVLMAFFPVVIAMVTGLKSIDPEMLELSATMGASPAQTFWKIRFPASLPQLFSGLKIAATMAVTGAVVGEFVGANEGLGFVILQANGNLDTPVLFAGLLVMSLLGVLLFVLVEVAEYFLLPWHASRRSTASATTF
>NZ_CP014859.1|WP_069849183.1|2830686_2831499_-|SAM-dependent-methyltransferase
MTYAGAAAGRSRFPDRIDLDIPNVARMYDYYLGGAHNFAADRELAEKAIEVRPEVITNARATRDFLRRVVNYALTRGIRQFLDLGTGIPSRGHVHEIAHRQHPETKVSYVDHDPVAVAHAVAILRGVDNTTVTLADLRDVDDVLERATKNLDLTQPVAVLATSVLHFVLDTEAAAEAVARYSEAIAPDSLFALSHSTAIEIPDEAEAIANLYKATATPITMRSPEVLRSWLTEAHLEPILPGIVDVTRWRPDTHPLPELSSVFGGVGLRR

Crispr_ID: NZ_CP014859_10

• CRISPR_ID: NZ_CP014859_10
• CRISPR_location: 3824870-3825141
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP014859_10

Consensus_repeat	Method
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	PILER-CR
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	CRISPRCasFinder
GTAAGCCCCGCGCAGGCGGGGGTG	CRT

spacers of NZ_CP014859_10

>10.1|3824898|33|NZ_CP014859|PILER-CR,CRISPRCasFinder
CCCGCACACGAAGCAGGCTCCCCGGATTCCCCA
>10.2|3824959|33|NZ_CP014859|PILER-CR,CRISPRCasFinder
CTACTGGTCGTGGCGGAAAGTCGAGTGGGTCCC
>10.3|3825020|33|NZ_CP014859|PILER-CR,CRISPRCasFinder
TTACACCAGCGCGGGCGGGAACTCCGGGGCGTT
>10.4|3825081|33|NZ_CP014859|CRISPRCasFinder
TCCTGGTCTCTTCCTGGTCATGGGTGATGATGA
>10.5|3824894|37|NZ_CP014859|CRT
GGCCCCCGCACACGAAGCAGGCTCCCCGGATTCCCCA
>10.6|3824955|37|NZ_CP014859|CRT
GGCCCTACTGGTCGTGGCGGAAAGTCGAGTGGGTCCC
>10.7|3825016|37|NZ_CP014859|CRT
GGCCTTACACCAGCGCGGGCGGGAACTCCGGGGCGTT
>10.8|3825077|37|NZ_CP014859|CRT
AGCCTCCTGGTCTCTTCCTGGTCATGGGTGATGATGA

CRISPR arrays and Neighbor proteins around NZ_CP014859_10

CRISPR arrays

The CRISPR arrays of NZ_CP014859_10

>merge|NZ_CP014859|10|3824870-3825141|PILER-CR,CRISPRCasFinder,CRT
GTAAGCCCCGCGCAGGCGGGGGTGGGCCCCCGCACACGAAGCAGGCTCCCCGGATTCCCCAGTAAGCCCCGCGCAGGCGGGGGTGGGCCCTACTGGTCGTGGCGGAAAGTCGAGTGGGTCCCGTAAGCCCCGCGCAGGCGGGGGTGGGCCTTACACCAGCGCGGGCGGGAACTCCGGGGCGTTGTAAGCCCCGCGCAGGCGGGGGTGAGCCTCCTGGTCTCTTCCTGGTCATGGGTGATGATGAGTAAGCCCCACGCAGGCGGGGCGGCCGA

>NZ_CP014859|10|7|3824870-3825080|PILER-CR
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	CCCGCACACGAAGCAGGCTCCCCGGATTCCCCA
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	CTACTGGTCGTGGCGGAAAGTCGAGTGGGTCCC
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	TTACACCAGCGCGGGCGGGAACTCCGGGGCGTT
GTAAGCCCCGCGCAGGCGGGGGTGAGCC

>NZ_CP014859|10|10|3824870-3825141|CRISPRCasFinder
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	CCCGCACACGAAGCAGGCTCCCCGGATTCCCCA
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	CTACTGGTCGTGGCGGAAAGTCGAGTGGGTCCC
GTAAGCCCCGCGCAGGCGGGGGTGGGCC	TTACACCAGCGCGGGCGGGAACTCCGGGGCGTT
GTAAGCCCCGCGCAGGCGGGGGTGAGCC	TCCTGGTCTCTTCCTGGTCATGGGTGATGATGA
GTAAGCCCCACGCAGGCGGGGCGGCCGA

>NZ_CP014859|10|5|3824870-3825137|CRT
GTAAGCCCCGCGCAGGCGGGGGTG	GGCCCCCGCACACGAAGCAGGCTCCCCGGATTCCCCA
GTAAGCCCCGCGCAGGCGGGGGTG	GGCCCTACTGGTCGTGGCGGAAAGTCGAGTGGGTCCC
GTAAGCCCCGCGCAGGCGGGGGTG	GGCCTTACACCAGCGCGGGCGGGAACTCCGGGGCGTT
GTAAGCCCCGCGCAGGCGGGGGTG	AGCCTCCTGGTCTCTTCCTGGTCATGGGTGATGATGA
GTAAGCCCCACGCAGGCGGGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_084643103.1|3836667_3838041_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP014859.1|WP_084643099.1|3830138_3831401_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|275254
NZ_CP014859.1|WP_084643101.1|3834209_3835358_+|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|237363
NZ_CP014859.1|WP_069853781.1|3835385_3836405_+|methyltransferase	unknown	unknown	gnl|CDD|275336
NZ_CP014859.1|WP_157421124.1|3819001_3822337_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850104.1|3814970_3816440_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP014859.1|WP_069850126.1|3831397_3832543_-|enduracididine-biosynthesis-enzyme-MppP	unknown	unknown	gnl|CDD|275255
NZ_CP014859.1|WP_069850102.1|3812443_3813682_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014859.1|WP_069850128.1|3832732_3833977_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014859.1|WP_157421123.1|3814106_3814775_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|236928
NZ_CP014859.1|WP_069850118.1|3825215_3826817_-|malate-synthase-A	unknown	unknown	gnl|CDD|236432
NZ_CP014859.1|WP_069850122.1|3827723_3829244_+|MFS-transporter	unknown	unknown	gnl|CDD|184957
NZ_CP014859.1|WP_069850108.1|3817148_3818750_-|carboxylesterase-family-protein	unknown	unknown	gnl|CDD|365897
NZ_CP014859.1|WP_069850114.1|3822890_3823676_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187589
NZ_CP014859.1|WP_069850120.1|3827046_3827571_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|274678
NZ_CP014859.1|WP_069850112.1|3822465_3822849_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069853777.1|3811772_3812441_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP014859.1|WP_069850116.1|3823834_3824626_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP014859.1|WP_069850124.1|3829305_3830142_-|enduracididine-biosynthesis-enzyme-MppR	unknown	unknown	gnl|CDD|275253
NZ_CP014859.1|WP_069850106.1|3816640_3817108_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_084643103.1|3836667_3838041_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.02171e-50
NZ_CP014859.1|WP_084643099.1|3830138_3831401_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|275254	TIGR04461, PLP-dependent_aminotransferse, enduracididine biosynthesis enzyme MppQ. Members of this family are MppQ, one of three enzymes involved in synthesizing enduracididine, a non-proteinogenic amino acid used in non-ribosomal peptide synthases to make natural products such as enduracidin from Streptomyces fungicidicus ATCC 21013. MppQ is a PLP-dependent enzyme, predicted by homology to be an aminotransferase.	1.11128e-130
NZ_CP014859.1|WP_069853781.1|3835385_3836405_+|methyltransferase	gnl|CDD|275336	TIGR04543, 2-ketoarginine_methyltransferase, 2-ketoarginine methyltransferase. This SAM-dependent C-methyltransferase performs the middle step of a three step conversion from arginine to beta-methylarginine. It performs a C-methylation at position 3 of 5-guanidino-2-oxopentanoic acid (keto-arginine). An aminotransferase converts arginine to 5-guanidino-2-oxopentanoic acid, and later converts 5-guanidino-3-methyl-2-oxopentanoic acid to beta-methylarginine.	2.95209e-14
NZ_CP014859.1|WP_069850120.1|3827046_3827571_+|TetR-family-transcriptional-regulator	gnl|CDD|274678	TIGR03613, RutR, pyrimidine utilization regulatory protein R. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the TetR family of transcriptional regulators defined by the N-teminal model pfam00440 and the C-terminal model pfam08362 (YcdC-like protein, C-terminal region).	5.7457e-10
NZ_CP014859.1|WP_069850104.1|3814970_3816440_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	8.78247e-46
NZ_CP014859.1|WP_069850126.1|3831397_3832543_-|enduracididine-biosynthesis-enzyme-MppP	gnl|CDD|275255	TIGR04462, PLP-dependent_aminotransferase, enduracididine biosynthesis enzyme MppP. Members of this family are MppP, one of three enzymes involved in synthesizing enduracididine, a non-proteinogenic amino acid used in non-ribosomal peptide synthases to make natural products such as enduracidin from Streptomyces fungicidicus ATCC 21013. MppP is a PLP-dependent enzyme, predicted by homology to be an aminotransferase.	2.12353e-155
NZ_CP014859.1|WP_069850114.1|3822890_3823676_-|SDR-family-oxidoreductase	gnl|CDD|187589	cd05328, 3alpha_HSD_SDR_c, alpha hydroxysteroid dehydrogenase (3alpha_HSD), classical (c) SDRs. Bacterial 3-alpha_HSD, which catalyzes the NAD-dependent oxidoreduction of hydroxysteroids, is a dimeric member of the classical SDR family. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.71961e-48
NZ_CP014859.1|WP_069850128.1|3832732_3833977_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.05991e-77
NZ_CP014859.1|WP_069850102.1|3812443_3813682_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	4.3446e-82
NZ_CP014859.1|WP_069850122.1|3827723_3829244_+|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	1.89261e-104
NZ_CP014859.1|WP_069850118.1|3825215_3826817_-|malate-synthase-A	gnl|CDD|236432	PRK09255, PRK09255, malate synthase; Validated.	0
NZ_CP014859.1|WP_157421123.1|3814106_3814775_-|TetR-family-transcriptional-regulator	gnl|CDD|236928	PRK11552, PRK11552, putative DNA-binding transcriptional regulator; Provisional.	1.06467e-06
NZ_CP014859.1|WP_069850108.1|3817148_3818750_-|carboxylesterase-family-protein	gnl|CDD|365897	pfam00135, COesterase, Carboxylesterase family.	1.88275e-127
NZ_CP014859.1|WP_084643101.1|3834209_3835358_+|branched-chain-amino-acid-aminotransferase	gnl|CDD|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	9.50577e-177
NZ_CP014859.1|WP_069853777.1|3811772_3812441_-|TetR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.98833e-08
NZ_CP014859.1|WP_069850116.1|3823834_3824626_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.75185e-68
NZ_CP014859.1|WP_069850124.1|3829305_3830142_-|enduracididine-biosynthesis-enzyme-MppR	gnl|CDD|275253	TIGR04460, endura_MppR, enduracididine biosynthesis enzyme MppR. Members of this family are MppR, one of three enzymes involved in synthesizing enduracididine, a non-proteinogenic amino acid used in non-ribosomal peptide synthases to make natural products such as enduracidin from Streptomyces fungicidicus ATCC 21013. MppR is belongs to the acetoacetate decarboxylase-like superfamily. MppR catalyzes an aldol condensation and a dehydration, not a decarboxylation.	2.36118e-131

Protein sequences

>NZ_CP014859.1|WP_069850116.1|3823834_3824626_-|IclR-family-transcriptional-regulator
MAEETGPGPVQSVVRAFAILEWLAAHGGEAGVSELAEGLDLALPTTHRLMRTLSTMGYVRQLPSRRYALGPGLVGLGDRASALLATWARPTLVELEQTVQETANLAVLDGDMVVYVAQVPSRHQMRMFTEVGRRVFPHSTGVGKALLAGLPDDRVRALLGRTGLPAYTPNTLTTEAEVLAELAGIRERGYAVDEGEQEIGVRCFAIAVPGGDTPTALSVSGPSSRVTAEAESWMVPALKKAAAELAEVLTPGEPSRFVEPRGR
>NZ_CP014859.1|WP_069850114.1|3822890_3823676_-|SDR-family-oxidoreductase
MARTYVVTGAASGIGATLAEKLSAEGHRVIGADLRGSDIDADLQTTDGRAALVSRATELTGGRIDGVAAVAGLSAPIPATAAVNYFGAVATLEGLRPLLAESEAPRAAVVASLAAIEPIDESLMAALSAGDEQETLAISERIAAEAAVGAGNLIYNSSKRALSLWLRAQAPTAAWAGASIPLNAVAPGVIETPMIAELLATEEGRAALSAGAPAPLNGPAAPPAAPANLLAWLLSPENTHVTGQIIYVDGGAESIRRPDLV
>NZ_CP014859.1|WP_069850112.1|3822465_3822849_-|hypothetical-protein
MGLVLFPDDGDLSSPDISWSHHGFHLLRQRLAEAEGFTLTAMAGFGGDRPWTDVVTTLAPLLDHPDDDGPDLTPAQCAAMLPRLETIVERWQREAHDPVVRHHLDDLRQLVVVLRFCLAEDVDLSFG
>NZ_CP014859.1|WP_157421124.1|3819001_3822337_+|hypothetical-protein
MSASEEPRADEPGEETVTSFIDSLDSLSFPARMQAITEHARALSHDDYVALHTALDNGTSEDERFLALQLAVVRRDLIGVERALADPVLRRRALSAAIRLPVSDLALTSVVTMGSRRDRIATYGVLRLSRRRALADSLVPLVLERYGRVELAELLVACSASVVARWLPGVEPSPGLLGRLARTAPEPVARFLAFEIARRERHAQVCWLRARSAALTVLATRYPSVLAEATARYGDAMRALVHVDADSYLDALLTRPALLIRELREGEPVHSRSLALSKAARTAIAELPTTEVAALLRLFVNGSTRASVLAAVALQDRRKCFDLVYPAGESPISTMGEELRVLPSADRVELAERILSANTGVRDLGWYRLAITSALPYDRAEPLLRTATSSHRYQQRRAAWMALLRCAAAERDPQAFASAVCSADRAWHDQDRIRSSVLQVLVETPARLSSEIPIRVFWEAVTATVGARDAAPRTCDLLARWLTRELTSSASRAQADRVVDLGKLLARVYADERTSVEFPARIPLPAGSVARLWTAIREQVIAGVRAHRFDLALRVARLFGTRLAAVPELDRLIGDIARTAVDSADRAAAANRWVTVDGLREQRVGELVSHDPSLGMVDRLWEVVVTRRTDLLDRMLAAGQSLPPVASGCHGRWTAAQRSSMQTRAMSVIENPTAGIRERAAAVELVSEGAALLSIVESAPQPIAAAALEALGRSVPVRMRSEQVLPVLLRHAAAASGPAPRAAVRALGSAVDGLPGDLAVDLLRPVVLDRSGSLGAAKEAVRVLGARQPVGALDLLVEAWADPGVHRDLRAAMAVALVGYLGTSEKISALLIEAIRGPAAVRTAVLSCGADSFTADRQGSWAGLLATVVDGLSPTDDPALCCEVVSAYEQCWRTEPRAVDRLSRLVGADAPREVAEAVWQLVLRTRRPTAVTGLVDRLVADIGSPDRGVAAAAWQRLKEMTNLPMWDRKAIDRQTVQALIDGCRAVGMQVSVATLTARLAADSLSGPPDPALWDELIAAIDERPARWPGKVMRWAGYVSANLDTVRVIIRHLLGQAGSIPGQLAVGVVALGARQAKLTDEWINLIDDLTQHQDPDVREAARSVRADRWLTG
>NZ_CP014859.1|WP_069850108.1|3817148_3818750_-|carboxylesterase-family-protein
MMTRNQLPRAGLTALVLVAAVACTPASDSNAEQPEPIGDRTVVEQGELAGRVDGEVIRYDGIPYAAPPVGEARLAPPAEPESWSGTFDATAPGPRCVQAPAPPTFEASSEEDCLSLNITAPSDTSQSSDHPVLVWLHGGGFSGGAGSDYDPKRLVVDGSLVVVTINYRLGALGFLGPEGTDANFGLLDQQAALRWVQNNIGDFGGDPTNVTLAGQSAGADSVCAQLASSSADGLYQRAILQSGSCSETNVTDAILPGAGPAADTWKPRDLVASQSADFAESVGCTAPETMVDCLRELPVEEFTSEAAAGYWSPTLGTPTLPDHPAVAIAGGRTSDVPILIGVNDDEGGYFAGTFFGADPLEQTDLDGLLASAAGPRTPEAIEAYPVEGRTPNRVWGDVISDRGYACPNLTSWRSMADHGTVYVYEFADETAPSWFGEIPSDLAGQGAVHGADIGYLFDLPAAELQLDEKQRALADRLRESWARFATTGDPAHGESDQRSDFDTDGQVMVFTADGPEPVSDTDLAARHHCEIWS
>NZ_CP014859.1|WP_069850106.1|3816640_3817108_+|hypothetical-protein
MDATALRNHICESFEGVAMMENAGDSFFAYDPDGDLPAQRWFPFATIVTDDNYDTASRLHRPDTYRINIGLSKTDYTARFGKAPTERDENGMFVTEFDYTALDLLMPHPVYGGQHWVCALNPADASLREVHGLLDAAYRFAARKHANRKADPAAS
>NZ_CP014859.1|WP_069850104.1|3814970_3816440_+|MFS-transporter
MGSSRLRTADSAAPASAPNAVVAVLAFAGIVVSLMQTVVIPLVPQLPRLLDATAADTAWAITATLLAASVSTPTVGKLGDMYGKRRMLLISLALLITGSVVCALSNSLTPMIVGRALQGMASGVIPLGISVMRDTLPAERLASATAMMSASLGVGGALGLPAAALLAERFDWHVLFWLAAALGAIVAVLVTRIVPESPVKTGGRFDLVGALGLSTALICLLLVISKGADWGWTNGLTLGLTGGAVVVLAAWAWWELRTTQPLVDLRTTGRRPVLLTNLASAVFGFSMFAMSLVMPQLLQLPVATGYGLGQSMMVVGLVLAPSGLVMMAMAPISARISRLGGPKTTLIVGTLVVAMGYGLNLMLMAELWHLVLVSSVIGAGIGLAYGAMPALIMSAVPVSETAAANSFNTLMRSIGTSTSSAVAGVVLAQMTITLGGAALPSQDGFRVIMAIGAGAALTSALIATFIPGRRPASPSSTPESVAVPAKVAG
>NZ_CP014859.1|WP_157421123.1|3814106_3814775_-|TetR-family-transcriptional-regulator
MLRVPTDVRRTPRAEQVGATREQILTTAERLFAEQGLYVVSNRQVSAAAGQGNNAAVGYHFGTKIDLVRAIVRRHTGHIETLRLELAEAVDGSSNVRDWIDCLVRPYAMHLKSLGGPTWFARFSAQVMTDPTFGRIMAEEALATESLRRVVVEIDRCLPQVPAEVSAERSDMVRHLIVHVLAERERAIAEREGTPRATWDTAATGLVDAITGLWTAPTSLGS
>NZ_CP014859.1|WP_069850102.1|3812443_3813682_-|cytochrome-P450
MEINVDAVAAGREEAPVLDYPIPASSALEPPAEWDRLRQSCPVARVRLPSGDEASLLTRYDDVKQVLADPRFRRRLDAPEAARVSTNESGGVFNGEMAAALPEETHQQWRRMVGKWFTAKRMTALRPAIEAMADRLIDDMVAAGPTADLKSALGFPLPVWVICDMLGVSEHDREKFAYWSNTLLSLTRFTQAEIDAAQAEFAAYMSNHIAATRENPGDDLISQLIADADAEGQIMPDLALLSTAQGLLVAGHETTSNMIGKMVAMLLADRSRWEQLLADRSLVRTAVEETLRLDANPGFGIPRFISEDTEIGGVAVPQHTTVVCSMGAANRDENTFDSAGEMDLTRTPNAHLAFGAGSHSCLGQSLARTELQAVLDVLLRRLPNLELAVPVEELKRVDGLIVGGLDELPVRW
>NZ_CP014859.1|WP_069853777.1|3811772_3812441_-|TetR-family-transcriptional-regulator
MPDATERPAPTRADRAGDTRELILAAAERLFAEHGVFAVSNRQIGEAAGQGNNFAVGYHFGSKAELVRTITRRHADIVERVRVRMLAEIGDSTDVRDWVACLVRPSTEHLDSLGSPTWYARFGAQVMTDPGLRRIVIEDSLATQPIQQVLDGLNRCLPSLPLSVHLERSAMARNLMSYTFAERERALAENTTTPRASWEDTATGLIDAIVGMWLAPVTTPTD
>NZ_CP014859.1|WP_069850118.1|3825215_3826817_-|malate-synthase-A
MSDTAPLTLRGTGVDRVDEVFTPEAIELIEMLHRRFEPTRVALLAERGERERRLAAGGSLDFLPETREIREDPTWTVPPPAPGLEDRRVEITGPTDRKMTINALNSGAKVWLADFEDANTPSWANMIDGQLNLRAALEGTLDFVSEAGKAYTLGEEIATIVVRPRGWHLIEKHVEVDGTPVAGGLVDFALYLVHCGRLQIDAGRGPYYYLPKLEGHREARLWNDVFTLAEQYLGLATGTIRATVLIETIPAAFEMEEILYELRDHSAGLNAGRWDYLFSIIKKFREHGEKMAFPDRSALTMTTSFMRAYTELLVTTCHRRGAHAIGGMAAAIPSRRDPDANAIALAKVREDKTREAGDGFDGSWVAHPDLVPVCREVFDGVLGDAPNQLDTRCEHVDVDAGQLLDVASVPGRVTTAGLHNDVAVGLRYLESWLRGSGAVAIFGLMEDAATAEISRSLIWQWVHTGARLEDDTAITPELIDTVITEQLDRVRGEIGEEAFAAGRWTDAEALFRHVALTDPFVDFLTVAAYDSLD
>NZ_CP014859.1|WP_069850120.1|3827046_3827571_+|TetR-family-transcriptional-regulator
MRPSSKTLILEAAMRVAENDGITSVTLDSVAEAAGLTKGGLLYHFRTRDALMLAIQRHIADCWEEKLLAALGKPVEESTQQERLAAYTKVSVDGASRADLVFVLESVGKPELCEPWNTMIERWSPDMTELDLFVAWLAADGLWLYEVSMGTTFSPELRTALTERISALAAPADG
>NZ_CP014859.1|WP_069850122.1|3827723_3829244_+|MFS-transporter
MSKVRRWLVLWTVSAGVLLIAVDMTVLYTALPTLTHDLQATASEKLWIINAYPLVMAGLLLGAGALGDRVGHKRMFLAGLVLFGLTSVLAAFAPSAAVLIAARAFLAVGAAAMMPATLALIRITFTDPREFGVAIGVWGGLSVCGVALGPIVGGLLLEYFWWGSAFLINVPVVAVAIVATILVAPDSKGDPAHPWDLIASLQVMVGLVGLVYAIKEVTKPDPSMSATVIALVVSLIGFWFFGRRQRKQPYPLIDFGLFRDRRILTGVIAASLSMFTVAGVQLVLTQRFQLVLELTPLHAGLIVAAEAVGALPASIVAGALLHRWGAKLVISAGMLISAIGVASLLLVVSADPIYATIGLVVTGAGLGAAMAAASSSILGNAPAHRAGMASSVEEVSYEFGSLTGVAILGSVLGLVYTSTVSLPDGADPSAANSIDDARIAAAGMSDGEASALLTAANSAFDTGYIVVVAVSAVALLGAAVLSAFLLRRSPTGNEMDKATAGSVHGH
>NZ_CP014859.1|WP_069850124.1|3829305_3830142_-|enduracididine-biosynthesis-enzyme-MppR
MSDPNHGPTGYSLPLSPTGASAMLTPPPWHFAGEVVMVDYRVDPDRAARFLPPGLDLGPDPGAAAAVFADWQWCSDDGAELTDPQRCQFGEFLILLGCSAGDRVMARCPYAWVDSAVPMLRGWVQGMPKQFGEIHQTRTRSVGRAGPRFATNGRYDGTLSVRGKRIVEASVTLSERLDEPPWLHTVPLVHTRTFPGWVSDTPPVEELVTSQVTGVEFSEILAGEATLDFGAALDDDFAGLAPVSVGRGYVFGYAETLCGGALLAPPTASPPVAVGMTG
>NZ_CP014859.1|WP_084643099.1|3830138_3831401_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MTTGLPMGADPADDRAAAAPSTEPSSTAGPLSHRRRWQLGVVQSMGPPELIDLVPGYLDPDLLPVDLLRGAYRDALAEFGSAALSYGDNQGAVEFREVMASLVSPACGPEHVLSTAGTSHALHLIATGLADPGDVVLVEQTGYDLGRGILADCGLRLREVPTDDDGLDPAALRSSVLEARSGGQRVAFVLVTPTFHNPTGRVMSLERRRELIAVAHHLGVLVVEDDAYADLGLTEPTLRPPTLLEMAGFTGVIALRTFSKTLGPGLRLGCMVAEQSLVQRLVSHGYFVSGGAPNHTTSLAITRLISDGDYHRHLEWLRTRLRTRRDALLGALRDGLGTDPVLRFTTPAGGYFLWAWSRGDHRETDLLAAAARAGVAVAEGSRFGTTSAPSARLAYSFNSPSRLADAGARLAEALTLEQNR
>NZ_CP014859.1|WP_069850126.1|3831397_3832543_-|enduracididine-biosynthesis-enzyme-MppP
MTTHATSSDRSLGNLTQFEYLALNNPLNLADGHARQELTPGQAGIIDELPALWADSVKRPVEEVEAAAHRAYFELLGQRDYRAADSQVLSCYSSSVAMEIFARSLATVTDSIMLVHPTFDNIPDILRGVGLRLVPLEEEPLHAGTIDREQLRSVGCVFVTTPNNPTGRVLSQQRLAELAALCAELDVLLTLDTSFRGFDPAAHYDHYAVLNASGCRWVVIEDTGKLWPTLELKIGWLVSSAHAGLPLARIYSDILLGVSPLVLSMVRRFSEDAAGGGLADLHRFIAGNRAQLRGALAGLPEVRIIDPDSKASVERIDLGKRSALDVWAALRDQNVFALPCQKFHWARPDEGDHSLRIALARPTATVAALTKALRSVLLDSR
>NZ_CP014859.1|WP_069850128.1|3832732_3833977_-|cytochrome-P450
MTNHHAVRGETASMIDLADPDTFLANDLTDFWRHLRHEQPVYRHPGTAQTGGFWVLSRHADLLAVYRDTEHFTSERGNMLDTLLHGGDSASGRMLVVTDGPRHRELRRVLLRAFAPRALRVVVERLQASVRRLVLDAARAGSVDFAADVASAIPLATICDLLAVPDVDRARILEWTSAAHGSENWLAVNEILTYFAGLARQRRDTPHSDVISLLATSEVDGKLLEEDEIILNCYSLILGGNETTRLSMIGGVLAFIENPEQWAALRDGLVEVDSAVEEVLRWTSPTMYMGRSVKSDVVLHDTEIKAGDVVTLWNIAANHDEAVFDQPERFDLARTPNNHLTFGHGQHFCLGAYLTRIELSTLFEVLRTAVADIALQGTPVRIHSTMLTGYSSLPVSLRPNPEGAARLAAPTTSD
>NZ_CP014859.1|WP_084643101.1|3834209_3835358_+|branched-chain-amino-acid-aminotransferase
MTQTRSTDHRGHSATENAPVFTRRTVPAANRIPAAQRSQRMRQPGFGRVLTEHMVTIRWSADLGWHDARLDPYQDLRLDPASVGLHHGQIVFEGLKAYSQPDGGVGVFRPDLASERLRRSARRLAMPELPESLFLAAITELVGADRDWVPATVGSSLYLRPVLLATESDLGLRPAREYLFLLIAFVTDNFFPGEVSPLTVWVSGDYVRAAPGGTGEAKTPGNYAGSLLPAQEAKARGCDQVVWLDAVERRWIEELGGMNLFFVYGPPDSPRLITPPLGGTILPGVTRDALITLARGSGYAVDEQPLSITEWRSAAEDGSMAETFACGTAAVVAPVGTVRSTEGEWQVGGGVSGPVTLGLRRALVDIQHGLSPDHHGWVFPVR
>NZ_CP014859.1|WP_069853781.1|3835385_3836405_+|methyltransferase
MTIRDRETVLDTDVREVVADAAGAAALLEIGDRLGLVPHIENGQAVTVAGLAEETLVPPEGVAKYLEAMTSAGIMSESTELPGTFTVADDFDQIRYESGYLSWALNANRPFVNNALEFLRDPRAAGKRHTRDGRQVAVASEWMGSKAFYPVALETILKARPSHVVDLGAGTARLLIEILGQLPETTAVALDLDGPSCKEAQAAAERAGMSDRLTVVERSIQSVAEDAGPVAGADVVHAGFVFHDMMPEEEDVADGVLANCRDALRPGGIMAITEAVPFVQNVRERRFSAIVTYYHQQFMRRRLLTEQEWTAKLLQAGFSEVECVPHRFPTGRLFIAKKK
>NZ_CP014859.1|WP_084643103.1|3836667_3838041_-|MFS-transporter
MVEPVREASTEADPAATAESTSTAAATPPSEAPPLPLSRNRNYHILWSSLLLSELSSAIVAIGLPLLILAVSGSAFQLGLVSSVLATARMLANVPAGVIADRWDRKKVMLWCQGLRALAMGALAATLLGGAYSLPLVLAVAVIEGVVGSVFAPAEDAALPRVVHRSQLSTAIARNTARPHIANLLGPAATGFVFGFHEMLPFALTVVLLTGSFVALVFLVLPRSKRTTPDAGSTADSPPAEPDRTGVRREVADGFRWALGNRAVLTTLVWLVFNQLCFGALVIVVLAASGEGDVAPGEVGLMMAFFGGGGILGASMASRVLPLLPSSVIVIGFSWVGAVLTAVMALVPPGLPLGLVLGATAFFVPLAATTIMTYQMLVTPDELRGRLSGIVGVCVGGANALGPMLGAMLIGFGGNSANALLLCGGALAVVALVSTFSPDLRRFPTLPTLDKPGRTGD

Crispr_ID: NZ_CP014859_11

• CRISPR_ID: NZ_CP014859_11
• CRISPR_location: 3877174-3877385
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP014859_11

Consensus_repeat	Method
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG	PILER-CR
GTCCGCCCCGCGCAAGCGGGGGTGAGCC	CRISPRCasFinder
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG	CRT

spacers of NZ_CP014859_11

>11.1|3877203|32|NZ_CP014859|PILER-CR,CRT
TGACACCCCCGGTTACCGCCGGGGGTGTCGTT
>11.2|3877264|32|NZ_CP014859|PILER-CR,CRT
ATCGCCGCGTCCCGGATCGCCTCCAACCTCGC
>11.3|3877325|32|NZ_CP014859|PILER-CR,CRT
CCATCCGCCAGCCAGTGCCGAGTGATATCCAG
>11.4|3877202|33|NZ_CP014859|CRISPRCasFinder
CTGACACCCCCGGTTACCGCCGGGGGTGTCGTT
>11.5|3877263|33|NZ_CP014859|CRISPRCasFinder
GATCGCCGCGTCCCGGATCGCCTCCAACCTCGC
>11.6|3877324|33|NZ_CP014859|CRISPRCasFinder
GCCATCCGCCAGCCAGTGCCGAGTGATATCCAG

CRISPR arrays and Neighbor proteins around NZ_CP014859_11

CRISPR arrays

The CRISPR arrays of NZ_CP014859_11

>merge|NZ_CP014859|11|3877174-3877385|PILER-CR,CRISPRCasFinder,CRT
GTCCGCCCCGCGCAAGCGGGGGTGAGCCCTGACACCCCCGGTTACCGCCGGGGGTGTCGTTGTCCGCCCCGCGCAAGCGGGGGTGAGCCGATCGCCGCGTCCCGGATCGCCTCCAACCTCGCGTCCGCCCCGCGCAAGCGGGGGTGAGCCGCCATCCGCCAGCCAGTGCCGAGTGATATCCAGGTCCGCCCCGCGCAAGCGGGGGTGAGCCG

>NZ_CP014859|11|8|3877174-3877385|PILER-CR
GTCCGCCCCGCGCAAGCGGGGGTGAGCCC	TGACACCCCCGGTTACCGCCGGGGGTGTCGTT
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG	ATCGCCGCGTCCCGGATCGCCTCCAACCTCGC
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG	CCATCCGCCAGCCAGTGCCGAGTGATATCCAG
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG

>NZ_CP014859|11|11|3877174-3877384|CRISPRCasFinder
GTCCGCCCCGCGCAAGCGGGGGTGAGCC	CTGACACCCCCGGTTACCGCCGGGGGTGTCGTT
GTCCGCCCCGCGCAAGCGGGGGTGAGCC	GATCGCCGCGTCCCGGATCGCCTCCAACCTCGC
GTCCGCCCCGCGCAAGCGGGGGTGAGCC	GCCATCCGCCAGCCAGTGCCGAGTGATATCCAG
GTCCGCCCCGCGCAAGCGGGGGTGAGCC

>NZ_CP014859|11|6|3877174-3877385|CRT
GTCCGCCCCGCGCAAGCGGGGGTGAGCCC	TGACACCCCCGGTTACCGCCGGGGGTGTCGTT
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG	ATCGCCGCGTCCCGGATCGCCTCCAACCTCGC
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG	CCATCCGCCAGCCAGTGCCGAGTGATATCCAG
GTCCGCCCCGCGCAAGCGGGGGTGAGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069850139.1|3868961_3869627_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014859.1|WP_069850148.1|3875985_3877053_+|ferric-reductase-like-transmembrane-domain-containing-protein	unknown	unknown	gnl|CDD|226582
NZ_CP014859.1|WP_069850140.1|3871015_3871231_-|MbtH-family-protein	unknown	unknown	gnl|CDD|225790
NZ_CP014859.1|WP_157421128.1|3889262_3889715_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850156.1|3887884_3888082_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069850146.1|3875192_3875708_+|lytic-polysaccharide-monooxygenase	unknown	unknown	gnl|CDD|237309
NZ_CP014859.1|WP_084643109.1|3877936_3878581_-|hypothetical-protein	unknown	unknown	gnl|CDD|375375
NZ_CP014859.1|WP_069850162.1|3889711_3889966_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069853785.1|3878860_3883234_-|glycoside-hydrolase-family-92-protein	unknown	unknown	gnl|CDD|377950
NZ_CP014859.1|WP_069850141.1|3871333_3872362_-|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl|CDD|188461
NZ_CP014859.1|WP_084643111.1|3887651_3887840_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069850137.1|3857934_3867660_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NZ_CP014859.1|WP_069850152.1|3885330_3886164_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381358
NZ_CP014859.1|WP_069850154.1|3886160_3887225_-|DUF3533-domain-containing-protein	unknown	unknown	gnl|CDD|274414
NZ_CP014859.1|WP_069850150.1|3883464_3885198_-|ubiquinone-dependent-pyruvate-dehydrogenase	unknown	unknown	gnl|CDD|181661
NZ_CP014859.1|WP_157421127.1|3872470_3873409_-|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238042
NZ_CP014859.1|WP_069850144.1|3873823_3874684_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213192
NZ_CP014859.1|WP_069853784.1|3869605_3870871_-|sensor-domain-containing-protein	unknown	unknown	gnl|CDD|226951
NZ_CP014859.1|WP_069850158.1|3888078_3888921_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP014859.1|WP_069850138.1|3867714_3868764_-|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl|CDD|367137

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069850139.1|3868961_3869627_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.48128e-37
NZ_CP014859.1|WP_069850148.1|3875985_3877053_+|ferric-reductase-like-transmembrane-domain-containing-protein	gnl|CDD|226582	COG4097, COG4097, Predicted ferric reductase [Inorganic ion transport and metabolism].	2.10811e-07
NZ_CP014859.1|WP_069850140.1|3871015_3871231_-|MbtH-family-protein	gnl|CDD|225790	COG3251, COG3251, Uncharacterized protein conserved in bacteria [Function unknown].	6.1442e-30
NZ_CP014859.1|WP_069850156.1|3887884_3888082_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.69791e-14
NZ_CP014859.1|WP_069850146.1|3875192_3875708_+|lytic-polysaccharide-monooxygenase	gnl|CDD|237309	PRK13211, PRK13211, N-acetylglucosamine-binding protein GbpA.	2.40726e-34
NZ_CP014859.1|WP_084643109.1|3877936_3878581_-|hypothetical-protein	gnl|CDD|375375	pfam17843, MycE_N, MycE methyltransferase N-terminal. This is the N-terminal domain found in MycE from the mycinamicin biosynthetic pathway. MycE is a tetramer of a two-domain polypeptide, comprising a C-terminal catalytic MT domain and an N-terminal auxiliary domain, which is important for quaternary assembly and for substrate binding.	6.10795e-16
NZ_CP014859.1|WP_069853785.1|3878860_3883234_-|glycoside-hydrolase-family-92-protein	gnl|CDD|377950	pfam07971, Glyco_hydro_92, Glycosyl hydrolase family 92. Members of this family are alpha-1,2-mannosidases, enzymes which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by hydrolysis. They are critical for the maturation of N-linked oligosaccharides and ER-associated degradation.	8.64222e-134
NZ_CP014859.1|WP_069850141.1|3871333_3872362_-|TauD/TfdA-family-dioxygenase	gnl|CDD|188461	TIGR03946, viomycin_VioC, arginine beta-hydroxylase, Fe(II)/alpha-ketoglutarate-dependent. Members of this protein family are L-arginine beta-hydroxylase, members of a broader family of enzymes dependent on Fe(II), alpha-ketoglutarate, and molecular oxygen. Enzymes in the broader family but excluded by this model include clavaminate synthase, taurine dioxygenase, and prolyl-4-hydroxylase. [Cellular processes, Biosynthesis of natural products].	2.41223e-119
NZ_CP014859.1|WP_084643111.1|3887651_3887840_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.80135e-14
NZ_CP014859.1|WP_069850137.1|3857934_3867660_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP014859.1|WP_069850152.1|3885330_3886164_-|aldo/keto-reductase	gnl|CDD|381358	cd19132, AKR_AKR5D1_E1, AKR5D and AKR5E families of aldo-keto reductase (AKR). 2,5-diketo-D-gluconic acid reductase B (DkgB) from Corynebacterium sp. and 2,5-diketo-D-gluconic acid reductase Zymomonas mobilis are founding members of aldo-keto reductase family 5 member D1 (AKR5D1) and E1 (AKR5E1), respectively. DkgB (EC 1.1.1.274), also called 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming), or 2,5-DKG reductase B, or 2,5-DKGR B, or 25DKGR-B, catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	1.44089e-151
NZ_CP014859.1|WP_069850154.1|3886160_3887225_-|DUF3533-domain-containing-protein	gnl|CDD|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	0.000221542
NZ_CP014859.1|WP_069850150.1|3883464_3885198_-|ubiquinone-dependent-pyruvate-dehydrogenase	gnl|CDD|181661	PRK09124, PRK09124, ubiquinone-dependent pyruvate dehydrogenase.	0
NZ_CP014859.1|WP_157421127.1|3872470_3873409_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	3.077e-07
NZ_CP014859.1|WP_069850144.1|3873823_3874684_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.81863e-30
NZ_CP014859.1|WP_069853784.1|3869605_3870871_-|sensor-domain-containing-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	9.39375e-31
NZ_CP014859.1|WP_069850158.1|3888078_3888921_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.99527e-08
NZ_CP014859.1|WP_069850138.1|3867714_3868764_-|TauD/TfdA-family-dioxygenase	gnl|CDD|367137	pfam02668, TauD, Taurine catabolism dioxygenase TauD, TfdA family. This family consists of taurine catabolism dioxygenases of the TauD, TfdA family. TauD from E. coli is a alpha-ketoglutarate-dependent taurine dioxygenase. This enzyme catalyzes the oxygenolytic release of sulfite from taurine. TfdA from Burkholderia sp. is a 2,4-dichlorophenoxyacetic acid/alpha-ketoglutarate dioxygenase. TfdA from Alcaligenes eutrophus JMP134 is a 2,4-dichlorophenoxyacetate monooxygenase. Also included are gamma-Butyrobetaine hydroxylase enzymes EC:1.14.11.1.	1.61074e-28

Protein sequences

>NZ_CP014859.1|WP_069850148.1|3875985_3877053_+|ferric-reductase-like-transmembrane-domain-containing-protein
MVATEARVDGERRRTGLRADLRAAIPDATAALVITVAIFIWLYSRVRAGISETVEVMPYLADANQYWMYWLCQAFGWSALLWAYITTVLGLVRSSSRPSWQPFSTVRIERWHRTTSLTTIGLMFAHAFLFFLELARTNDNNLDFAGRWVNAFVESFVPGGYPSGTGQVAILLGLLALYLAIPLGLLYYLRNRTGARMWRALHRFVIVVYILSAWHTLLYGTNVWFDGWPRTALWLLQIPIAVLLILRLVSPARRGDKLGRGTPVSHVIRRVVAVLAVVAAIGAILAVVITGRDGGRTRDVTGAAPSVLPWMVWTGFAVFVLGVGVAVLLVRRAERARVAARKSPSEPASEPADAE
>NZ_CP014859.1|WP_069850146.1|3875192_3875708_+|lytic-polysaccharide-monooxygenase
MRKKRTAAAIIGAAIAPLLLAVVPAGTANAHAYVSSPPSRQAQCAANTVPCGDIKYEPQSVEGPKGLTSCSGGNSRFSELDDDSKGWTVTPVGTTTNFDWTVRVSHATTTWQYFVGGTKLAEFNDGGARPGETVSHQVDFGGIRGQQKVLAVWNIADTEMAFYACIDVNIG
>NZ_CP014859.1|WP_069850144.1|3873823_3874684_-|ATP-binding-cassette-domain-containing-protein
MMENASSASQPRNGRKPAYLTGPPADSRLLDVTARDVDRQPAAVNPDPAAALELVQVGKIHLDGDAAVCAVEDVSLRCPTGTWTVIVGPARSGRSSLLRCAAGLDRVTSGRVLLGGVDVTETSGVDRRGHVGLVSSVAEFAGSPTVEHYLRRPAPEVGAASDRLVTALLAHVGLEGRRDVAPSALSVEEQRCIVLLGALTRRPAVLIADEPTVEMGADLAEAAMSLLEQWVVAAGLTVLMASEELSGVRSADTACFLAAGRIVDSCSLGPRAVFETTGKSWSELCR
>NZ_CP014859.1|WP_157421127.1|3872470_3873409_-|winged-helix-turn-helix-transcriptional-regulator
MVSTLGPVVESVFALDLFGQQRGSRAARWRRRVREQLGTGLTAVQQLNRECRAVPDLLWLLRRQEADGDHLGADHDARVAARRLAATVFIFCRAAILPYWSKMQAHLESERDVRGRMAITNGVETLLSALHPKVSWNSPVLEIASEQDHDVYLDGRGLVLSPSLFLLEKNCVFIDSEKQSGMPALIFSVQSDPHELSDPFDVWESGDRALGALVGATRAAALRALVESGTTGELSDRLGISLSGASKHATVLRKAGLIITSRNRATALHTLTPLGMALLQRSPRSSNGAEERNSPAAGQRVGATLCVPDEPV
>NZ_CP014859.1|WP_069850141.1|3871333_3872362_-|TauD/TfdA-family-dioxygenase
MVVFELNNTEIEQINRVVGELAGRFSTVEDPEFLRESQLWAHELPRRLRQQLVDFRTDEPSGTLIVRGLPVDEAGLVPTPTTSGHRPVPSPTLSYDLAFFLIGGLLGESIGWATQQDGYLMHDVYPVQSFENDQIGWGSKELLTWHTEDAFHPMRTDYLGLMCLRNPDAVETTVADIADVKIDDELREVLAQPRFRILPDDSHRPGAWKGDEPEEQILIDLLRRSRERVEQALRTPEPVPVLFGSPVDPYLRLDPHYMKDVQGEEEQQALDSVIGAVDAAMGGVVLAPGDICFIDNYRVVHGRKPFKARFDGSDRWLRRLNITRDLRKSREYRASAPDRVIY
>NZ_CP014859.1|WP_069850140.1|3871015_3871231_-|MbtH-family-protein
MSTNPFDDPDGRYLVLVNEEGQHSLWPSFAEVPAGWTAALEETDRQSALDYVNENWTDMRPKSLIRAMDGS
>NZ_CP014859.1|WP_069853784.1|3869605_3870871_-|sensor-domain-containing-protein
MHPLRFLISGWPWRCLLYLACGVFAALPALAVGRWISLSGSITSYLVSVLGVLLISLLGAVPFAALERRRLGILNPEWARRRSGHERPGGPVARLRAWLREQDIWREFGYALVTLTILSLINLAVTVSVLGILFAPLGAGMALILDTGSGPTGGLTVNVPTIMMIAGVWLLIMPVAAYATTAVAAGQAALARFLLLPSGTTMAAKVQELSQSRLRLVDVFEAERSRIERDLHDGAQQRLVSLAMTLGMAELSLADDRTERADSDVARLVVAARKEAQAALGELRELIRGIHPQVLTDLGIEAAVAEVTTRCPIPVGLDIDLPRRPARSVEAVAYFVVSEALANVVKHSQARRAEVAGAPAGAGFVLTVVDDGIGGADPRGGTGLQGLVDRVAVVGGKISLSSPPGGPTELRVELPWHPDSE
>NZ_CP014859.1|WP_069850139.1|3868961_3869627_-|response-regulator-transcription-factor
MAPGLRIVLAEDAVLLRAGLVELLGRFQHRVVAAVGDATALAAAVAEHKPDLIVTDVRMPPGYSDEGLRAAVELRSRYPGLGVLVLTQYVATAYAFELIEADGDRRSGGIGYLLKDRVADVKEFVDAVERIAKGDMVIDPEVVRQLLRRERADRPLRRLTPREHQVLALMAEGRTNAAIAATLFISQAAVSKNIGSIFTKLDLSDSDGNHRVLAVLTYLRG
>NZ_CP014859.1|WP_069850138.1|3867714_3868764_-|TauD/TfdA-family-dioxygenase
MTSTLAADLSTLGPLHGTVEGNAHTQLVAYGPESGDTTEAALRSASIVDWAGEHREALIKALHNHGAVLVRGAVPTPELLSGVAEAVGGTLLEYNERTTPRSTVSGNVYTSTEYPANQTIPQHNELAYSANSPRWLFFACGIPASSGGATPLADSGAVLRRLPAELVSRFRDLGVLYTRCYMAGMGLTWQEAFQTEERAKVEEYCHANGMEFEWFGEDELRTRSRRPAVVTDPDSGQEVWFNQAHLFHLSNLPTNVAAALSAMYEERDYPRHSFYGDGTPLAEDDLALIRTAYDDTVYATPWETGDLLVVNNLRVSHGRQPYEGARKIMVAMAGTLDVGPAPELAGAGV
>NZ_CP014859.1|WP_069850137.1|3857934_3867660_-|non-ribosomal-peptide-synthetase
MSQSDRETSARIDDSGRGAALDEVHRHRVLVEFNDTAADYPRDRCLHGLFADRVRRAPDDLAVVCRGTRLTARELDIRANRLANELVARGVGPEVLVGLCLERGIDLVISALAVLKAGGAYVPLDPNYPADRLGMMLTDTAARLVLTERRLAGRVPDSAATVLYLDEEQQAIEQASAAAPSVVVGPQNLAVVLYTSGSTGVPKGAMLSHRSLVRLVRPGGIIDFGPDEVSGMLASPSFDASAFEMWNALLGGAGLAVYPAGTPSADQLREFLTDNDVTTMVFTTGFFHALVDSGVSVLDGLRQIVVGGEVLSPVHCAKATDRLPGLRIANVYGPTECGSVTSFAVFDPEVGTAQPLPIGSLLANTRVVLLDDSLAPVPVGEPGEAYIAGDGLGRGFLTGAGLSAERFVANPHGAPGERMYRTGDLLRWRSDGVLEFVGRVDDQVKVRGFRIELGEIENVLAQRPGVAAAVVLVREDQPGLRRLVGYVVGDAGETLDGDVLREQLAASMPEHLVPSAIVVLDRFPLTPNGKVDRRSLPAPSAPAEPAASFQAPTTAAERLLAEVWSEVLGVEQVSISDDFFADLHGDSILAMRMLSKARAVSGADLPARALFDSPTIAALAVLLPAETVGGDEATPIPAVRRDGPLPLSSAQRRMWILEEIEPDGIDYNTTAGVRLAGPLDPAALKIALDRLVARHEPLRTTFAVGDGAGEQIVHPHGTAVLEIVDLSSVDRAEQASAVDRAVRAEAARPFDLRTGPLLHTLLLRLSESEHLMVIGQRHIITDGWSVGLVVGDLLALYASVRGGTPAELPSLPVQYADFAVWEDGRLADRSLDGELEYWKRRLAGNRPLELPTDRPRPPIRTSAGADHRFLVPAEVVDGLTELGRGHNATLFMTLTATVQVLLARYSGQSDVTIGTVSAGRDRAELENLLGFFVRTLVLRSEVTPTLSFADLLDDTRETVLGAFAHQEVPFDRLVDALATERDPSRTPLFQVIVALQKPFVATTRIADLLVEEFPLPKVAVPFDLFIEFWPQGDTLEAVINYNTDLFDATTIERMGTHLSTLLASVVADPATPVSRLPMLTEAERGRLLSGHQPEPLALGAADGQPPTEETVPTAFLRQVRRTPDAVALVADGVSWTYAELAARAMRLAERLRTAGVGVEQPVALLMDRSPAVVVAELAILVAGGAYLPLDLRAPVPRLRALLADASPEVLITSGDRRSMAEQIHDGPIIVLEDREPIEEPAVSDLGRTPAIVHADNLAYIIYTSGSTGSPKGVAARHRDVLTLAAHRDYSGGAHRRILLHSASAFDAATYETWVPLLTGGSIVVAPPSDLDADGVQRLIAEHGVTALFLTAGLFRHFAEHAPHCLAGVEEVWAGGDVVPASAVRRVLQHCPGLTVVDAYGPTETTTFVLTHRIGAAAEIRREVVPIGLPMDGVRAFVLDPMLQPVPVGVAGELYLAGAGVTRGYLNAPAATAQRFVADPFAADGSPMYRAGDLVRWRDSVGRDGREIEFVGRVDDQIKIRGFRIEPGEVEAALTRLPGVDEALVLIRHRDGRAQLIGYLVAAHGITLDHAALAGELGHVLPTYMVPTAFVTMDELPLTTNGKVDRAALPLPAAPDSVGTVEPRTELERTLAEIWAELLGVPKVGVEDNFFALGGDSILALQVVYRARSLGLVVTSRDLFRGQTVAALAAEVASSTAPVAEQGAVSGTVPLTPIQRWFFEIRDTNPDRFNQTVRVELAGSVNRQALRAAMQAVLDKHDALRMRFERVDGRWRQYNAVVEETEVLRFVDATVATDGSEPPGGSELPEQLDGRIAAETAALASRVDIGTGPLIAGTVLDHEPRPLLLLAAHHLAVDGVSWRILLADLATGYRQASAGLPIELGAKTTSFRDWALNLTRLAEQEGFAAEREYWSMVASTDRPRLPVDLDGANTAGSARTVVSGLSVENTAALLRDVPSAYRTRINDVLLTAFGRTMAEWTGADRVLLDLEGHGREDLFDGVDLTGTVGWFTSMFPVSLAVDASEGPDTGDPTADWAPLLKSVKEQLHAIPGNGLGYGALRYLATDRPAAESEPQISFNYLGKIDGAESTEESLYHSGDLELDLDEPADALRPHLLDLVGRIRAGRLEFHWVYSDQIHHETTVRELARRFIEALTELIGHCTSPGAGGRTPSDFPLAGLDQPTVDRIVGDGRSVEDIYPLTPMQSGMLFHSLLDDHGGLYFEQTSLLIDGITDPELLAAAWQRTVARTPALRTEIAIHDLPHPVQVVRSAARLPVRQLDWRELDTSAAQHAAEEYLAEDTARGLDLAQAPLMRLAIARLTDRRVRLFWTFHHTLLDGWSVQRVLGDVFGEYAALVDDTSFVPPVRRPFRDYLDWLSHRDEQAARVYWSGVLADLESPTALPFDHPRIEQRRAPVSAEYLLELPAEVSENLHTVARKAEITLNTLVQGVWAVLLSLYSGSSDVCFGATVSGRPTELAGADSIVGLFINTLPVRVSVDASARLGDWLRTIQAEQAESRGHEQVSLAELRGWSALPGGVDLFDSIVIFENYPFDRGMAREHGIELLDIASDSGTNYPLNVIAYPGRQLSLLLNYDTALFDESTIERLAGHLRTLFDAVITRPDAPVRELRLLTEGERGQFVAWNDTDTPLSEGHSVHGLFAAQARRSPDALALTSSTVRLTYAELEARANRLAHRLIGLGVGPDVAVAICLERGVDVAVAALAVLKAGGAYVPLDPDMPSARSAFVVADTGAPVVVTQRSVRIDWAESVAVVRLDEDWLALAELPDTPPVTEVRPDNLAYVIYTSGSTGAPKGVMVSHRNAVALFDWQQRVYDIGAEDRTCLLAALSFDASVWELWPYFLAGARVDVPDPKILGDAAAMAAWFVDNGTTVCFLLAARVDALFDEPLFPATRLRLILTGGDTVRRRPAAGTTPRLFNHYGATEMTVVSTYGEVLQEGRQTSDRLPDVGIPVFGDTVHVLDRHGNPLPVGVAGEIHLGGIGVSRGYLNQPGLTSERFVADPFGPPGSRLYRTGDLGRWNTEGRLEFLERVDDQVKIRGFRVEVGEVEHAILRLPWVSEAVVVARKDEDGHTRLIGYLVLDPAERDGTEDPVVTRLRAALAETLPEYMVPSVFVTLDEFPLTANAKIDLRALPEPTRQDRLATEYVAPRDPTEIALAELWATVLEAERVGVHDDFFQLGGDSIVCLRLTSRIRLAFGVEVSPRDVFDAPTVGSFAELLRDRILADLERAARG
>NZ_CP014859.1|WP_084643109.1|3877936_3878581_-|hypothetical-protein
MGTLILAAGGRDEQIVEAIDEIGLAATAEVVHAEILLRLTPPQLDRLVRVQLELRHGTERSDAILVFDGESVTAEPGRIEDEAQQPTVRYDLYDVVRSLFGPGESNTPSRNVVLSMPKMHSWAEGADWALMQARSTSAVIAAIADRPTDLGALSLANGSDKWGGCTTTPRTTSVISPLSPTPPCACWRSASAATRSRTSAAAGCGCGGVTSAEA
>NZ_CP014859.1|WP_069853785.1|3878860_3883234_-|glycoside-hydrolase-family-92-protein
MEATPHPASSAGGPRPGSGAAPRRAGSTLRRTIGSGLVAVLVAGLAPLATTLPAHAAELDPFDAVDPFIGTELDTTQNKGNSAYGNTWPGATVPFGMVQSSPTTYRTSDGDQKGGYEYTADQLRGFGMTRLSGTGCEGRNSGFDFPILPYTETLVDDTLPVNPATDIEDYYLDFDHDDETAEPGYYRVDLPANVDVELTATTRTAVSAFDFNGRGTRDSTLLLDVAGSNNRVFGSGVEIDGRTVSGWVESATVCDEGGRYRAYFSASFDRNIKSFGTWDRDGVHLGSTGTESINPDGDGKHAAGAFLTFPAGARVTAKVGLSYVSIDNAEENRETEVGSTRFDNVRTSAAETWREALGTLDVRGGTAEERTKFYTAVYHSLLHPNVFDDVNGEYAGYDGETKTVAEGRHHYVNHAGWDGYRSHAQLVALLFPKVGDDINQSLVDMVDQTGRWPNWPHLNQPQQKMSGDSLQTVLASIDAFGSTDYDRQAALDSMVDSQTLPADETNRAHAHQYFSTGMIENRRGDSATSKVLEYSINDFSIAQLADRLDDQNAYRQFMVRAQNWQNVFDDETSHIRPRERNGFDRDFELGERGNQFEQATGYQYGWMVPHNVGTLVDKRGGIDTVTAALDDHTSELDAGVYGTADAYLSNQPSFSMPFVYHWLRQPHRTTDVLYRAVEEMYDTTPSGLPGNDDLGSLSAWYVWANIGLFPSIYGTANLMVSAPMFEGVEIRSADSDRAISIDAPGAGEDGKYTVGLDVDGEATTASWLPEDFAQRGGSLRFELAATPGGWGTGAQDVPPSYTDGTDGRNNIGITPEGRGDLGSLDLSDNSLSRDALADAGAAPGAELPLGDTGVVFTWPDTEPGEPDNWIPHGQRIELGGETATGISFLGLATNGPATGRATVEYVDGSTQDVTVAFTDWTPGTNYQYGNEPLVTAVGRNRADGSADTAETKVFGTVPQLLDATKPVASVTLPQGTDRGIMHVFDVALTSNPDLEVPGALPERIVLTPTEQPSTSQAITWRTDAAIDQGAAEIRMAGTEQWRTVEARTSEEQVSGGLPTRSHSAVVDGLEPSTEYEYRVGTDRWWSEEYRFTTAGAAGEEFTFIHLGDAQNELTDKWTPVVEDAFERFPDAVASVHAGDLVNTAGNDGEWGEWFTAMDGQSQTSNVIATPGNHEYSGDALLKSWGSQFEYPANGPVSTPAADDSPAEIQRAAYEEHMAEVLTESAYYTDYQGVRFLSLSASHRDARQLMTPPDLPACEVDCPEPERLWLDIQGRWLEQILADNPNKWTVVVFHHPVFSTAVGRDEPLVREMWLPVLQRNDIDLVLMGHDHTYARGYVDADATDTPGITTGPVYAVSVAGPKYYEQQDEDDNIWTRNGATQVARAGHTSTFQGITVTENQIRYESIVAAKWDDQSTTDKEVGETLDAFTITKYDDGTKYVTEDGVDVPAGPDGVGPTS
>NZ_CP014859.1|WP_069850150.1|3883464_3885198_-|ubiquinone-dependent-pyruvate-dehydrogenase
MRTVADTTVEILHESGVQRIYGIAGDSLNGLTDALRRAGTITWQGVRHEEAAAFAAAAEAALTGELAVCAGSCGPGNTHLVNGLFDAQRSRVPVLAIAAQIPAVEIGSGYFQETHPTELFRECSVYLELVSVREQLPRMLEIAMRTAVEQRGVAIIVVPGEIFLEESAGRRRSTPIRAIPKITRPADAELRAAADVLNAAKRVTILGGAGVAGAHSELLAIADRLKAPVVHALRGKEFIEYDNPYDVGMTGLLGFSSGYGAMEKCDTLLMLGTDFPYQQFLPSKAKVIQVDIRGEQLGRRVPLDIGLVGSVKDTIDALLPLLDADRDEEHLKTSRANYAKARKELDALATNDRNRTPIHPQYVARLVSELAAEDAVVIPDVGSPVVWASRYLKMNGSRRLIGSFVHGTMATAVPHAIGAQSAFPQRQTIALAGDGGLSMLLGELLTVRQHELPVKIIVFNNASLNFVELEMKSAGLVNFATDLTDPNFATIARAMGFHAARVEQPDNLEAALRAAFAHDGPALVDVVTARQELSIPPTITPAQVKGFGLWALRTIMSGRGDELIDLADTNVFRRLFG
>NZ_CP014859.1|WP_069850152.1|3885330_3886164_-|aldo/keto-reductase
MTLPERTVAGHALPIIGFGTYRLTGATGTDTIVDAIHAGYRLIDSAVNYENEGAVGAAVRNSGVPRDELIVTSKLPGRHHAADQARATIEESVFRTGLDHIDLYLIHWPNPKVDRYVEAWGALIEARQRGLIRDIGVSNFLPEHLARLTAETGVAPMVNQIELHPYFPQTEALAYHREHGILTESWSPIGRANDLLSDPKIVSIANKLGISPAQTVLAWHIKVGAIPLPKASSIERQRENIDLADIELSEDDVAAITGLGFPEGRTNDQDPAVYQEF
>NZ_CP014859.1|WP_069850154.1|3886160_3887225_-|DUF3533-domain-containing-protein
MRRILPGPHLPAFVISLIIAVFGALFVASYSIAMGDPHAHAVPIGVVGDASDKERLRGAIDAATGARFEAVDVDSRDAAVEAIGQQRLYGALLMGEDHAELLISSASGASMARIIGQDTTAIEASLGTRLTVLDLHPLSQKDPAGLVLFYMALASTIIGFVGAIQTRVNAGGLTLAGELGWDATRAVLAGLLISVTVGPALGLERFPVLWVWAVLAATMFIVGAVYSIFRILFGNSWGLLPTWVLFVLISNPSSGGVVAPELLPSFYEFMGRWLPTGATVRALRDLTYFPDAIHAEPYLVLGCWLLGAPILFVLLRRRRFGTGPSRAPNRERSTTNPESAGTPDTGNPDATEAR
>NZ_CP014859.1|WP_084643111.1|3887651_3887840_-|DUF397-domain-containing-protein
MLALGNWRKSTRSQTATACIEVGQAPGHVGIRDTKDRAGGTLVVDRVAFGAFLTAVKADRLG
>NZ_CP014859.1|WP_069850156.1|3887884_3888082_-|DUF397-domain-containing-protein
MTRLLEHATWRKARRSQNTSACIEVGQAPGLIGIRDTKDRAGGTLVVDRVTFGAFLAAVKSNRVG
>NZ_CP014859.1|WP_069850158.1|3888078_3888921_-|helix-turn-helix-domain-containing-protein
MVVTPKGQALGREMKNVRERVGATARAIAEQMGVSTATISRWESGNRSPRPEDVASYLTALRAPNGVRNELIDMARDTEGRQWLAVGYPEQGHALAALLEAERDATHIVSVSPLIIPGLLQTVDYARSIIGAGGVPAEEVEIRVKTRVGRRSVLTGRNAPAFLALLGEAALRRLVGGPQVQSDQLRVLLEISRLPSVDLRVIPFTAPWSPDMEGLYDWFAFRDRDPVVHVENRRSALVFHDRDDVAPYEAATDTVMRVAMSSARTSELILDVISELEATP
>NZ_CP014859.1|WP_157421128.1|3889262_3889715_+|hypothetical-protein
MRSFRDPAGWSDWIPATFRSDPPRSMWVTVSCNRARQHVLVEGHLPDRTPILAAITAAAAAEACEGLRYRHRRSVTVPALGTGLQDREFSVSDPGDGGAVLAIDNRFGPLGRWSVHPDRVPELSWALKYAHALATGRNPLDVAAAGGGSR
>NZ_CP014859.1|WP_069850162.1|3889711_3889966_+|hypothetical-protein
MTAHWFVRTVAEGDTHRARTEHWTRDGRAHIRPLCDPTALFTALNRQPIALPYYDNQSCSTCLTTEPARLHLIHAGRRHLAAVR

Crispr_ID: NZ_CP014859_12

• CRISPR_ID: NZ_CP014859_12
• CRISPR_location: 3928451-3929219
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 10 spacers

Consensus repeat of NZ_CP014859_12

Consensus_repeat	Method
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	PILER-CR
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CRISPRCasFinder
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CRT

spacers of NZ_CP014859_12

>12.1|3928488|36|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
GGGGTGCCCGACCACGATTCGCCAGACGACACTCGT
>12.2|3928561|35|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CCAAGCATGGGATGCCCTACCGCGTGGTCTGGATT
>12.3|3928633|38|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CTACGCGGCTTGTGGAGGTCGAAGTTCGTCGCGGTGGA
>12.4|3928708|35|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
AGGAAGGACTTCCAGCGACTCCGGTTCGGGCTCCG
>12.5|3928780|36|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
GGGCCTGGTGCGCACCGCGCACCTACGGCTTCCGTG
>12.6|3928853|36|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CGTCGTGCCCTCGGGCGCGGCCCCGGGGTTGGGGTG
>12.7|3928926|35|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
TGGGTTCTTGTGCTCGTGCGCCAGATGGTGTTGGC
>12.8|3928998|36|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CTTGGTCTCGCCTATGAGGCTCTGCAAGCCTCCGAG
>12.9|3929071|38|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CCCTTCCGTCACAGGCAGGGGCGAGACCAGCATTACGA
>12.10|3929146|37|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
GCCGGTCCGAGATGAGCTTGTTAACCGCTGCCTGGTC

CRISPR arrays and Neighbor proteins around NZ_CP014859_12

CRISPR arrays

The CRISPR arrays of NZ_CP014859_12

>merge|NZ_CP014859|12|3928451-3929219|PILER-CR,CRISPRCasFinder,CRT
GTTGCGATCCTCACCGGCCCAAAAGGGCCGATGCCACGGGGTGCCCGACCACGATTCGCCAGACGACACTCGTGTTGCGATCCTCACCGGCCCGAAAGGGCCGATGCCACCCAAGCATGGGATGCCCTACCGCGTGGTCTGGATTGTTGCGATCCTCACCGGCCCGAAAGGGCCGGTGCCACCTACGCGGCTTGTGGAGGTCGAAGTTCGTCGCGGTGGAGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCACAGGAAGGACTTCCAGCGACTCCGGTTCGGGCTCCGGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCACGGGCCTGGTGCGCACCGCGCACCTACGGCTTCCGTGGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCACCGTCGTGCCCTCGGGCGCGGCCCCGGGGTTGGGGTGGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCACTGGGTTCTTGTGCTCGTGCGCCAGATGGTGTTGGCGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCACCTTGGTCTCGCCTATGAGGCTCTGCAAGCCTCCGAGGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCACCCCTTCCGTCACAGGCAGGGGCGAGACCAGCATTACGAGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCACGCCGGTCCGAGATGAGCTTGTTAACCGCTGCCTGGTCGTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC

>NZ_CP014859|12|9|3928451-3929219|PILER-CR
GTTGCGATCCTCACCGGCCCAAAAGGGCCGATGCCAC	GGGGTGCCCGACCACGATTCGCCAGACGACACTCGT
GTTGCGATCCTCACCGGCCCGAAAGGGCCGATGCCAC	CCAAGCATGGGATGCCCTACCGCGTGGTCTGGATT
GTTGCGATCCTCACCGGCCCGAAAGGGCCGGTGCCAC	CTACGCGGCTTGTGGAGGTCGAAGTTCGTCGCGGTGGA
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	AGGAAGGACTTCCAGCGACTCCGGTTCGGGCTCCG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	GGGCCTGGTGCGCACCGCGCACCTACGGCTTCCGTG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CGTCGTGCCCTCGGGCGCGGCCCCGGGGTTGGGGTG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	TGGGTTCTTGTGCTCGTGCGCCAGATGGTGTTGGC
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CTTGGTCTCGCCTATGAGGCTCTGCAAGCCTCCGAG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CCCTTCCGTCACAGGCAGGGGCGAGACCAGCATTACGA
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	GCCGGTCCGAGATGAGCTTGTTAACCGCTGCCTGGTC
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC

>NZ_CP014859|12|12|3928451-3929219|CRISPRCasFinder
GTTGCGATCCTCACCGGCCCAAAAGGGCCGATGCCAC	GGGGTGCCCGACCACGATTCGCCAGACGACACTCGT
GTTGCGATCCTCACCGGCCCGAAAGGGCCGATGCCAC	CCAAGCATGGGATGCCCTACCGCGTGGTCTGGATT
GTTGCGATCCTCACCGGCCCGAAAGGGCCGGTGCCAC	CTACGCGGCTTGTGGAGGTCGAAGTTCGTCGCGGTGGA
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	AGGAAGGACTTCCAGCGACTCCGGTTCGGGCTCCG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	GGGCCTGGTGCGCACCGCGCACCTACGGCTTCCGTG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CGTCGTGCCCTCGGGCGCGGCCCCGGGGTTGGGGTG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	TGGGTTCTTGTGCTCGTGCGCCAGATGGTGTTGGC
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CTTGGTCTCGCCTATGAGGCTCTGCAAGCCTCCGAG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CCCTTCCGTCACAGGCAGGGGCGAGACCAGCATTACGA
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	GCCGGTCCGAGATGAGCTTGTTAACCGCTGCCTGGTC
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC

>NZ_CP014859|12|7|3928451-3929219|CRT
GTTGCGATCCTCACCGGCCCAAAAGGGCCGATGCCAC	GGGGTGCCCGACCACGATTCGCCAGACGACACTCGT
GTTGCGATCCTCACCGGCCCGAAAGGGCCGATGCCAC	CCAAGCATGGGATGCCCTACCGCGTGGTCTGGATT
GTTGCGATCCTCACCGGCCCGAAAGGGCCGGTGCCAC	CTACGCGGCTTGTGGAGGTCGAAGTTCGTCGCGGTGGA
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	AGGAAGGACTTCCAGCGACTCCGGTTCGGGCTCCG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	GGGCCTGGTGCGCACCGCGCACCTACGGCTTCCGTG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CGTCGTGCCCTCGGGCGCGGCCCCGGGGTTGGGGTG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	TGGGTTCTTGTGCTCGTGCGCCAGATGGTGTTGGC
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CTTGGTCTCGCCTATGAGGCTCTGCAAGCCTCCGAG
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	CCCTTCCGTCACAGGCAGGGGCGAGACCAGCATTACGA
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC	GCCGGTCCGAGATGAGCTTGTTAACCGCTGCCTGGTC
GTTGCGATCCTCACCGGCCCAAAAGGGCCGGTGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069850207.1|3925688_3925895_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069853796.1|3923017_3923749_+|DNA-alkylation-repair-protein	unknown	unknown	gnl|CDD|378033
NZ_CP014859.1|WP_069853800.1|3937759_3938488_-|serine-protease	unknown	unknown	gnl|CDD|238113
NZ_CP014859.1|WP_069853799.1|3935407_3936397_-|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176190
NZ_CP014859.1|WP_069850201.1|3921127_3921922_-|TSUP-family-transporter	unknown	unknown	gnl|CDD|376667
NZ_CP014859.1|WP_069853801.1|3939629_3940430_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|212492
NZ_CP014859.1|WP_069850218.1|3931756_3932632_-|phosphotransferase	unknown	unknown	gnl|CDD|309685
NZ_CP014859.1|WP_069850203.1|3922004_3922937_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP014859.1|WP_069850222.1|3936522_3937437_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP014859.1|WP_084643130.1|3923874_3924903_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP014859.1|WP_069850211.1|3926131_3926914_-|lysophospholipase	unknown	unknown	gnl|CDD|378820
NZ_CP014859.1|WP_069850216.1|3929542_3930676_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP014859.1|WP_069850209.1|3925895_3926135_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850226.1|3939084_3939495_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP014859.1|WP_069850224.1|3938831_3939050_+|FCD-domain-containing-protein	unknown	unknown	gnl|CDD|183181
NZ_CP014859.1|WP_157421130.1|3927056_3927242_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069853798.1|3930876_3931734_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274648
NZ_CP014859.1|WP_084643134.1|3932708_3934865_-|S9-family-peptidase	unknown	unknown	gnl|CDD|224422
NZ_CP014859.1|WP_084643706.1|3927242_3928166_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP014859.1|WP_069853797.1|3925110_3925692_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|197775

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069853796.1|3923017_3923749_+|DNA-alkylation-repair-protein	gnl|CDD|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	5.93716e-61
NZ_CP014859.1|WP_069853800.1|3937759_3938488_-|serine-protease	gnl|CDD|238113	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.	1.26221e-36
NZ_CP014859.1|WP_069853799.1|3935407_3936397_-|NADP-dependent-oxidoreductase	gnl|CDD|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	6.30384e-142
NZ_CP014859.1|WP_069850201.1|3921127_3921922_-|TSUP-family-transporter	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.38863e-10
NZ_CP014859.1|WP_069853801.1|3939629_3940430_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|212492	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs. Classical SDR subgroup containing retinol-DHs, LPORs, and related proteins. Retinol is processed by a medium chain alcohol dehydrogenase followed by retinol-DHs. Pchlide reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. This subgroup includes the human proteins: retinol dehydrogenase -12, -13 ,and -14, dehydrogenase/reductase SDR family member (DHRS)-12 , -13 and -X (a DHRS on chromosome X), and WWOX (WW domain-containing oxidoreductase), as well as a Neurospora crassa SDR encoded by the blue light inducible bli-4 gene. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.58689e-23
NZ_CP014859.1|WP_069850218.1|3931756_3932632_-|phosphotransferase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	5.20165e-16
NZ_CP014859.1|WP_069850203.1|3922004_3922937_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	8.07854e-36
NZ_CP014859.1|WP_084643130.1|3923874_3924903_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.01188e-29
NZ_CP014859.1|WP_069850211.1|3926131_3926914_-|lysophospholipase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	2.82519e-10
NZ_CP014859.1|WP_069850216.1|3929542_3930676_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	7.0264e-39
NZ_CP014859.1|WP_069850226.1|3939084_3939495_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.80183e-37
NZ_CP014859.1|WP_069850224.1|3938831_3939050_+|FCD-domain-containing-protein	gnl|CDD|183181	PRK11534, PRK11534, DNA-binding transcriptional regulator CsiR; Provisional.	0.00822058
NZ_CP014859.1|WP_069850222.1|3936522_3937437_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.14314e-36
NZ_CP014859.1|WP_069853798.1|3930876_3931734_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274648	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes one such subfamily, exemplified by Rv1855c from Mycobacterium tuberculosis. [Unknown function, Enzymes of unknown specificity].	2.72891e-67
NZ_CP014859.1|WP_084643134.1|3932708_3934865_-|S9-family-peptidase	gnl|CDD|224422	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism].	2.44272e-82
NZ_CP014859.1|WP_084643706.1|3927242_3928166_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	7.49709e-39
NZ_CP014859.1|WP_069853797.1|3925110_3925692_+|helix-turn-helix-domain-containing-protein	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	1.67887e-14

Protein sequences

>NZ_CP014859.1|WP_084643706.1|3927242_3928166_-|LysR-family-transcriptional-regulator
MVDVSLDLLQLRTFVAIEDCGGFGRAASVLRISQPTVSQHVRQLERRLRQTLVEKDGRRARFTAAGERLLVEARRIMAVHDEALNRLTSDTRTGLVIGSAETAAEQVLPELLSSLRDAYPGRPVRFHLDRSTQLIDSVDRGLVDLAVILGFPGDIPGRLVGNLPLRWYAAPGWQPPARSDPWPLVAYREPCGMRQRALQRLGEADRTVDVVAESTSVEGVIAAVRAGLGVAVLPSAGRAPSGLTRLGGLPDLGSIGVHLATRRGLDLNLETAALDVLESFFGSLDIPWSAGSGRALPAPRSPEITTP
>NZ_CP014859.1|WP_157421130.1|3927056_3927242_+|hypothetical-protein
MFDLVVDPADSSNARRRAVPTAISLSPSQLRRGTVGASNDEFRDRFIGISNGRSRNRIGAA
>NZ_CP014859.1|WP_069850211.1|3926131_3926914_-|lysophospholipase
MKETRVTIAEAAPLTATWPEPTGIALRGTVIIVPGRGEHPGVYERFGRRISADGYRVWAVADPTVDADRATRQLDTLIANDALPRPLVLVGSDTGALFAAASLADRTAPGATSISGLVLAGLPSRAEYWADTADWQDELDARTGCPTHQGVLDLDPSVRRGALGRRAPAEWFDRADPASITVPILGLHGESDMISPFAGVRGWYDAAPHADLVGLVGGRHDALNDQTHRSAAATTVLFLERLRLGSELPVIARPASAVAE
>NZ_CP014859.1|WP_069850209.1|3925895_3926135_-|hypothetical-protein
MSHDVVIGRGPGPAESLPGPDGKTPARRVAAGYEPADISSVNVEAESTVDITELAVHPRPDRAATGRSTWQSYIRGACL
>NZ_CP014859.1|WP_069850207.1|3925688_3925895_+|hypothetical-protein
MTGVQGIERVLASHRLARIRDRSWVEDRFTRFGWSGTSSPRPLAQPAAFEHADAVESGEQHHPAVEHV
>NZ_CP014859.1|WP_069853797.1|3925110_3925692_+|helix-turn-helix-domain-containing-protein
MDQETEDVLGVVGPRLRALRRDRGFTLADVATRTGVSESTLSRLESGQRRATLELLLPLSRTYDIPLDDLVGAPRTGDPRIHLKPIGRFGMVFVPLSRRPGGTQAFKMIIPAREKPLEPTPQTHDGFEWLYVLNGRLRLVLGERDLTLSPGEAAEFDTSLPHWLGTADGGAVELLILFGLQGIRAHVQANPSS
>NZ_CP014859.1|WP_084643130.1|3923874_3924903_-|alpha/beta-hydrolase
MITESCPSTRRFDRSTRMAATLPLAVLLTFGAAACATPAVEDIAPHAVATHDDPAFDHTFRHEFADVDGVRMHYVTGGSGSPVVLIHGWPQTWYGWWSIMPQLAEHHTVYAIDLPGLGDSTGSPTGYDKATLARYVHTLIANQLGVDDARVVGHDLGAAVAFQYAAQFPGDTVALGYLDLPLPGPAIDAATYRSMSWHIAFHSQERVPETVVGDDVREYLELFYPQVAYEGSSFGGTSDRSPFTQAEIDEYARTYGRPEVLAGGFELYRALDQDVSDTMEAVPTDVPTLLMTAEGQLEPVQATVAPRLTNIVRAVDVPNAGHWLVEENPEFVTDELLDFLAN
>NZ_CP014859.1|WP_069853796.1|3923017_3923749_+|DNA-alkylation-repair-protein
MPIELTAARFVERLESHRSEEELRKIQRYFKSGVGEYGEGDEFIGVRMGQVFALAKEFIDLAPAELERLLESPIHEVRAGALSVMDKQARRKKTDEQRRRELFELYLSRIDRINNWDLVDLAAPYVVGGYLFDRSRDVLYRLARSRNIWERRTAIVGTSYFLRHHEVHDTFAIAEILLRDEEDLIHKATGGWVREAGRKDPARLLAFLDQHAAAMPRTMLRYAIEHLDADQRAYYRGLKKRTA
>NZ_CP014859.1|WP_069850203.1|3922004_3922937_+|LysR-family-transcriptional-regulator
MRYDLDDLRLFLHVVDEGSITAGARRMHLSLPSASARVRALEHHAGVTLLVRGRRGVRPTPAGSTLARHAHEVLAQTALLEGAVASYARPSAAPLVLLAGGSAMHRFVPQALVSFLRSHPDVDVTVSECRTPETMRLLAAGEADLGIVQSHEAIGDELPIEALGDDSLVAIGQAGGVLVDRAAVSYREVAEHPLVGLGPGSSLQHWIETSLGANAPAARFRTLVPDLTTLIALAVAGVGLAVVPRRSVAPESAVEVCELTDSWARRAHLLCWGARERGEPEIRTALADHLRAAARRGTEGGSSIVDGHQS
>NZ_CP014859.1|WP_069850201.1|3921127_3921922_-|TSUP-family-transporter
MAEFLFLLLAGAVAGALNAAGGGGTFVALPALVATGLSPVTANAAATVALVPGALVSAWVYRREVLPIGTTSTKALLTASVLGGGAGAALLLTLPSESFDAAVPWLLAFATIVLAFGRPLSAKLSALRQRRATAGSGSVPSAAIIGTRTILIGQFILAIYGGYFGGAVGILMLAFWSIGLGLDTATSNPMRIVQLGAVYLTATLLFLVASDVLAEPLPLAAMLVGALAGGYGGAHLVRRLPPGVLRTVVLTTAVVMTVLYFLRG
>NZ_CP014859.1|WP_069850216.1|3929542_3930676_+|serine-hydrolase
MSPSADGTVVAGYQRVAEAFERSLSDDGTETAQCCVHVDGEMVVDLWSGLPEALEVVFSATKGATAACANLLVQRGLLQLDARVAEYWPAYGVRGKESTLVRWLLSHRAGVLTPREQLTMDALAEWDLVAATLAAQTPAWEPGTAYGYHAQSFGWLVGELVRLVDGRSLGTFFREELAQPAGAEFWIGLPQDQEPRVVPSVADDPALPPGTDPAQLDLSSYFGPHHLDAFTLGGMLPEDIVAAATDRRYRAAEVGASGGVANGRGLSRLYRLLLDEFTSATVEDILTPETEGTDLVLSSPAVTVTQLFGRGFDVSPPVGAPPGTRTFGHGGSGGISAFADPDRRLSFGYTTSRLVPGPPGMDPRTSSLVEAVYETTG
>NZ_CP014859.1|WP_069853798.1|3930876_3931734_+|LLM-class-flavin-dependent-oxidoreductase
MPSFGIMTAPMQIDYHRLLPVWQEADTIPEIEHAWLFDHLMPIGGDPMGPALEGWTLLGALAAQTRRLRIGLMVTSNRFRPPAMLAKIATTVDIVADGRLDFGIGAGSRPSHPMARREYESHGLPFHDFAHSVGSLAEACTVIRRLWTEPEPFDFDGDYVRLVGAFGNPKPVQRPHPPILIGGRSSATLRVVAEHADLWNIPGGDIEDVVRRSALLDRYCTEIGRDPVTITRSIHLPVDYDAPAPTRTAIGQAIDAGFGHVVLGLPAPYPPHAAQWVAEELIATT
>NZ_CP014859.1|WP_069850218.1|3931756_3932632_-|phosphotransferase
MEDVATRLTDRFGPQAASWLAEVPTVAAQLASRWGLTLGEMFESGASSVVLRCRWRDGIPAVLKLTPDRALLAKQVEMLRVFEASGRVPAVLATDAEVGAMVLEEILPGTEATDLPAVDLPERWAELLGDLHAVPVPADWPWDLRGRFAESFERVGKRLDDPKVGARIDAATWQRAIRRCETLLNTQTAPVLLHGDLHLGNVLDGGPSRGLVAIDPKACVGDPCFDAVDYVVEGAGQEGIEARCLRVATACGLDADRLLEWSRVVAPMFAVSHLAYGGPEPVLDELLTLIR
>NZ_CP014859.1|WP_084643134.1|3932708_3934865_-|S9-family-peptidase
MTGSSKDSPPVARVDTVEESRFGIRLSDPYRWMETDGPELRSWLTAQADHTEAALNSLPNRARIRARVEELTSTGTSESGFVAGVDGLLFFLREDPQTTVPVLMVRTGAEPAEPSAGRVLADPVAVTGDAHGGIDWYVPSPDGSHVAVGFSAGGSEDSILRIVVVETGELLDDVVHSSLHGAVSWLPDGTALIYHRYPEPTPDFAADERRFDSQSCLHRLGTPAEQDVPVLARGRNDAVPLTERDRPFVLVQPDSDWVVAVVSHSALVGPLTERISDCSIYLAPRAALAEPASCPWRQVANPADDITAFAMRDDVLYLVAHGGTPRGRVVAVSAVDPELSRAPVLVPESDCVLIAVRVVGDYLLVRELHAGADRLRRVPLTGGDTQEIELPVAGTIQEITGLPSGSGALLLTTSHTAPPMLLHYDGATGTVRDTGWLPGSDTEVLMATDVVVRARDGAAVPLRLIHRAGLPLNGDNPTLLSGYGSYGHVLAAEFTPDLRVWCEDGGIYAVAGLRGGGEHGRAWHAAGRGPHKENTITDFIDCAEYLIAHGYTRPAWLAGEGASAGGIPVGGALVRRPELWAAMVLRVPVTNATRQEFSENGPVNVPEFGTITTEDGLRDLLIIDSYLRVRDGQQYPAVLLTTGLNDPRVAVWQPAKTTARLQAATASDRPVLLRVDAHAGHGAGATRAQRVDSITDILAFLRDQLGDRTLTRRGPAVE
>NZ_CP014859.1|WP_069853799.1|3935407_3936397_-|NADP-dependent-oxidoreductase
MTVIRQVAPPAGAPKKDDFEAVTLPIPERDDNQLLVENLYLSVDPYMRELMEWGGWELAGGLLGDAIGRVLESSDPTVPVGSIVRHRHGWRTHALPAVTEVTRIHPADGVPLSAYLGILGLTGFTAYVGLVKIAALRPGDDLFISAAAGAVGGATAQIARLLGARRIVGSAGSAAKIAYLTEKLGLDAAFDYHAGSVTEQLAEAAPDGIDVYFDNVGGDHLEAAIAAMKDHGRIAACGAVAQYNNLRTPPAAPHNLFDIVEKNLRLEGYLADRHLNSIPEFERFLVPRVQDGTVLIDEVVVDGIENTVDAFIGMLRGENIGKMLVRVAE
>NZ_CP014859.1|WP_069850222.1|3936522_3937437_+|LysR-family-transcriptional-regulator
MAVVRLGPVADSYPSPHELRLLLAVERTGSFTGAAEELGLTQSAVSHAVRTIERKIGAVLFERGRTGSGPTDAGERALVHARHILRQYEVLQVEARGAANGRIGGPLRIAAFRTAALHLLPAALDRLASRHPELSPQVSIVRELGRGPMGEVADGRADVAVATLPEDVVPEPGLLVGELLREPYLFVYPTGHPAPRTLPLIDWDENCSAATLGWWSSQDWLPPAKITAADDGVVLQMVAQGLGMAILPKLSLTNAPAGVTITQLGDQAPTRRTVHLTSRAGAHSLGVRELVHALRATRDEQLTR
>NZ_CP014859.1|WP_069853800.1|3937759_3938488_-|serine-protease
MRARRLIGMFASLGTALALLVAGPTAAMGATHEAGQPAETLIVGGVDADQTYSFMVAATSRGGAYCGGTLIAPTWVVTAEHCLGGIDGVRVGSLHTGSGGETAGVAQKIANSQADIALLRLDRAVSATPAPLADTTGGNGAPLRLLGWGATCSPENCPPPQVLQQLDTSVVGISGPYIRVDNPGGDSGACFGDSGGPALRQGANGWELVGVTSSGPAICGTEPSNYTDATQFRNWIAQHTGI
>NZ_CP014859.1|WP_069850224.1|3938831_3939050_+|FCD-domain-containing-protein
MAIGSIDKADRYRRLALEIARTDAERAKKDEEHASLLELVVAGDVEGAAAVMREHIDTILSAQAARRPTRPD
>NZ_CP014859.1|WP_069850226.1|3939084_3939495_-|helix-turn-helix-transcriptional-regulator
MSGTNTDVPAVLAYELPNPVPTAELEICPVGGIFRRVGDRWSLILIALLGRRPYRYNELHRAIEGISQRMLTRTLRGLEIDGLVHREVFPTVPPSVEYRLTPLGSSLLGPVSALAEWAVRHEPDMAAARLRNGSVE
>NZ_CP014859.1|WP_069853801.1|3939629_3940430_+|SDR-family-NAD(P)-dependent-oxidoreductase
MGRATALERLARGDRVTVIGSNPTRGKALLDEAANPRLRFVCADLSTVAEVDRVVGEITEQHDRIDALGLFANRVRPKRVETADGWEATFALYYLSRYLLGRRLAPLLDASPRSVIINVAGVGNTAGGIHWADPQLTENYGTVRAQLQAGRANDLLGVSYAENADSTARYVLYHPGFTKSGAEAHPSALVSGMIKVLGTFFARPVAASVRPIVEWIEHPPAAALTAVDRGKPVDPTLKTLDPKEAARLAEYTAQLLRSTNTDSEAT

Crispr_ID: NZ_CP014859_13

• CRISPR_ID: NZ_CP014859_13
• CRISPR_location: 4574297-4575057
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 12 spacers

Consensus repeat of NZ_CP014859_13

Consensus_repeat	Method
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CRISPRCasFinder
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CRT
GTCTGCCCCGCGCGAGCGGGGGTGAGCC	PILER-CR

spacers of NZ_CP014859_13

>13.1|4574325|33|NZ_CP014859|CRISPRCasFinder
TGCAAGTGGCAGTGCGGTCACCCAGCCGGGCTG
>13.2|4574386|34|NZ_CP014859|CRISPRCasFinder,CRT
GATGCACCACAGGGAGCACAAGAACGAAAGCACT
>13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
GGGTCGTCGGTGGCCTTCCCGGCGCGCTCTGCC
>13.4|4574509|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
GACGCCTCGATCGACAGCTGACCGACCACCCCC
>13.5|4574570|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
TCGATCCGGGGCATCACCGTGTACCGCAACGGC
>13.6|4574631|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
TCAGACCTTCTTTCGCCCGAAAATCAATTCCAG
>13.7|4574692|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
CAGGCCAGCGACGACTCCGCGTTCGACAGCCGC
>13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
GTTCCCGGAGGTCCCGTACACCCACACCGAGCC
>13.9|4574814|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
GACGTAGCAATATACGGAATCACTCGGCGCGGG
>13.10|4574875|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
GCCGCCACGATCACCACCCTCACCGTCCACCCG
>13.11|4574936|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
TCCGCCATCACGGCCGGCTGGAAATTCTCCGGC
>13.12|4574997|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
CCCGGTGGGCGACACGACAACTCCGAGCCTCCC

CRISPR arrays and Neighbor proteins around NZ_CP014859_13

CRISPR arrays

The CRISPR arrays of NZ_CP014859_13

>merge|NZ_CP014859|13|4574297-4575057|CRISPRCasFinder,CRT,PILER-CR
GGCATACCCCCGCTTGTCCCGGGCGGACTGCAAGTGGCAGTGCGGTCACCCAGCCGGGCTGGCTCGCCCCCCGCTCACACGGGGCGGACGATGCACCACAGGGAGCACAAGAACGAAAGCACTGGCTCACCCCCGCTCGCGCGGGGCAGACGGGTCGTCGGTGGCCTTCCCGGCGCGCTCTGCCGGCTCACCCCCGCTCGCGCGGGGCAGACGACGCCTCGATCGACAGCTGACCGACCACCCCCGGCTCACCCCCGCTCGCGCGGGGCAGACTCGATCCGGGGCATCACCGTGTACCGCAACGGCGGCTCACCCCCGCTCGCGCGGGGCAGACTCAGACCTTCTTTCGCCCGAAAATCAATTCCAGGGCTCACCCCCGCTCGCGCGGGGCAGACCAGGCCAGCGACGACTCCGCGTTCGACAGCCGCGGCTCACCCCCGCTCGCGCGGGGCAGACGTTCCCGGAGGTCCCGTACACCCACACCGAGCCGGCTCACCCCCGCTCGCGCGGGGCAGACGACGTAGCAATATACGGAATCACTCGGCGCGGGGGCTCACCCCCGCTCGCGCGGGGCAGACGCCGCCACGATCACCACCCTCACCGTCCACCCGGGCTCACCCCCGCTCGCGCGGGGCAGACTCCGCCATCACGGCCGGCTGGAAATTCTCCGGCGGCTCACCCCCGCTCGCGCGGGGCAGACCCCGGTGGGCGACACGACAACTCCGAGCCTCCCGGCTCACCCCCGCTCGCGCGGGGCAGAC

>NZ_CP014859|13|13|4574297-4575057|CRISPRCasFinder
GGCATACCCCCGCTTGTCCCGGGCGGAC	TGCAAGTGGCAGTGCGGTCACCCAGCCGGGCTG
GCTCGCCCCCCGCTCACACGGGGCGGAC	GATGCACCACAGGGAGCACAAGAACGAAAGCACT
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GGGTCGTCGGTGGCCTTCCCGGCGCGCTCTGCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GACGCCTCGATCGACAGCTGACCGACCACCCCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCGATCCGGGGCATCACCGTGTACCGCAACGGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCAGACCTTCTTTCGCCCGAAAATCAATTCCAG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CAGGCCAGCGACGACTCCGCGTTCGACAGCCGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GTTCCCGGAGGTCCCGTACACCCACACCGAGCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GACGTAGCAATATACGGAATCACTCGGCGCGGG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GCCGCCACGATCACCACCCTCACCGTCCACCCG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCCGCCATCACGGCCGGCTGGAAATTCTCCGGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CCCGGTGGGCGACACGACAACTCCGAGCCTCCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC

>NZ_CP014859|13|8|4574358-4575057|CRT
GCTCGCCCCCCGCTCACACGGGGCGGAC	GATGCACCACAGGGAGCACAAGAACGAAAGCACT
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GGGTCGTCGGTGGCCTTCCCGGCGCGCTCTGCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GACGCCTCGATCGACAGCTGACCGACCACCCCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCGATCCGGGGCATCACCGTGTACCGCAACGGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCAGACCTTCTTTCGCCCGAAAATCAATTCCAG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CAGGCCAGCGACGACTCCGCGTTCGACAGCCGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GTTCCCGGAGGTCCCGTACACCCACACCGAGCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GACGTAGCAATATACGGAATCACTCGGCGCGGG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GCCGCCACGATCACCACCCTCACCGTCCACCCG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCCGCCATCACGGCCGGCTGGAAATTCTCCGGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CCCGGTGGGCGACACGACAACTCCGAGCCTCCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC

>NZ_CP014859|13|10|4574420-4575057|PILER-CR
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GGGTCGTCGGTGGCCTTCCCGGCGCGCTCTGCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GACGCCTCGATCGACAGCTGACCGACCACCCCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCGATCCGGGGCATCACCGTGTACCGCAACGGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCAGACCTTCTTTCGCCCGAAAATCAATTCCAG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CAGGCCAGCGACGACTCCGCGTTCGACAGCCGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GTTCCCGGAGGTCCCGTACACCCACACCGAGCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GACGTAGCAATATACGGAATCACTCGGCGCGGG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	GCCGCCACGATCACCACCCTCACCGTCCACCCG
GGCTCACCCCCGCTCGCGCGGGGCAGAC	TCCGCCATCACGGCCGGCTGGAAATTCTCCGGC
GGCTCACCCCCGCTCGCGCGGGGCAGAC	CCCGGTGGGCGACACGACAACTCCGAGCCTCCC
GGCTCACCCCCGCTCGCGCGGGGCAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_084643252.1|4585676_4588955_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173812
NZ_CP014859.1|WP_069850915.1|4582034_4585310_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173812
NZ_CP014859.1|WP_069850898.1|4567863_4568247_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850901.1|4569977_4571513_+|hypothetical-protein	unknown	unknown	gnl|CDD|276938
NZ_CP014859.1|WP_069850895.1|4566266_4567112_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP014859.1|WP_157421181.1|4569229_4569922_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850906.1|4575563_4577018_-|hypothetical-protein	unknown	unknown	gnl|CDD|236740
NZ_CP014859.1|WP_084643251.1|4572694_4573183_+|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240039
NZ_CP014859.1|WP_069850911.1|4578410_4579172_-|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl|CDD|224268
NZ_CP014859.1|WP_157421180.1|4568294_4568477_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850908.1|4577014_4577473_-|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl|CDD|273298
NZ_CP014859.1|WP_084643757.1|4579368_4580061_+|methyltransferase	unknown	unknown	gnl|CDD|237872
NZ_CP014859.1|WP_069853908.1|4575264_4575549_-|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|376329
NZ_CP014859.1|WP_069850903.1|4571571_4572312_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235975
NZ_CP014859.1|WP_157421179.1|4567415_4567655_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850909.1|4577469_4578414_-|1-phosphofructokinase	unknown	unknown	gnl|CDD|238570
NZ_CP014859.1|WP_157421182.1|4572393_4572657_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850914.1|4580793_4581621_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|212492
NZ_CP014859.1|WP_157421183.1|4573533_4573860_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850912.1|4580194_4580737_+|dihydrofolate-reductase-family-protein	unknown	unknown	gnl|CDD|223340

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069850906.1|4575563_4577018_-|hypothetical-protein	gnl|CDD|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	1.55567e-119
NZ_CP014859.1|WP_069850895.1|4566266_4567112_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.90867e-11
NZ_CP014859.1|WP_084643252.1|4585676_4588955_+|S8-family-serine-peptidase	gnl|CDD|173812	cd07487, Peptidases_S8_1, Peptidase S8 family domain, uncharacterized subfamily 1. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.02849e-71
NZ_CP014859.1|WP_069850915.1|4582034_4585310_+|S8-family-serine-peptidase	gnl|CDD|173812	cd07487, Peptidases_S8_1, Peptidase S8 family domain, uncharacterized subfamily 1. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	4.35107e-66
NZ_CP014859.1|WP_084643251.1|4572694_4573183_+|NUDIX-domain-containing-protein	gnl|CDD|240039	cd04683, Nudix_Hydrolase_24, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	3.52909e-50
NZ_CP014859.1|WP_069850911.1|4578410_4579172_-|DeoR/GlpR-transcriptional-regulator	gnl|CDD|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	7.78191e-81
NZ_CP014859.1|WP_069850908.1|4577014_4577473_-|PTS-sugar-transporter-subunit-IIA	gnl|CDD|273298	TIGR00848, Includes:_Phosphotransferase_enzyme_IIA_component, PTS system, fructose subfamily, IIA component. 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	2.27021e-39
NZ_CP014859.1|WP_069853908.1|4575264_4575549_-|HPr-family-phosphocarrier-protein	gnl|CDD|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	7.74939e-19
NZ_CP014859.1|WP_069850903.1|4571571_4572312_+|SDR-family-oxidoreductase	gnl|CDD|235975	PRK07231, FabG-like, SDR family oxidoreductase.	2.59784e-84
NZ_CP014859.1|WP_069850909.1|4577469_4578414_-|1-phosphofructokinase	gnl|CDD|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	5.6094e-106
NZ_CP014859.1|WP_084643757.1|4579368_4580061_+|methyltransferase	gnl|CDD|237872	PRK14968, PRK14968, putative methyltransferase; Provisional.	4.29011e-31
NZ_CP014859.1|WP_069850914.1|4580793_4581621_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|212492	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs. Classical SDR subgroup containing retinol-DHs, LPORs, and related proteins. Retinol is processed by a medium chain alcohol dehydrogenase followed by retinol-DHs. Pchlide reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. This subgroup includes the human proteins: retinol dehydrogenase -12, -13 ,and -14, dehydrogenase/reductase SDR family member (DHRS)-12 , -13 and -X (a DHRS on chromosome X), and WWOX (WW domain-containing oxidoreductase), as well as a Neurospora crassa SDR encoded by the blue light inducible bli-4 gene. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.1026e-36
NZ_CP014859.1|WP_069850901.1|4569977_4571513_+|hypothetical-protein	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	2.10597e-19
NZ_CP014859.1|WP_069850912.1|4580194_4580737_+|dihydrofolate-reductase-family-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	7.50634e-17

Protein sequences

>NZ_CP014859.1|WP_157421183.1|4573533_4573860_+|hypothetical-protein
MAEERWREHLEDIDDPTRAEACYEEGWDQPRCGRYLAGVVRDVLSVSDAASATEWPQLAEAAESMVGSYEEYEAQGCHESESANCSGLRTEVLLGPSLVLVGYAADQI
>NZ_CP014859.1|WP_084643251.1|4572694_4573183_+|NUDIX-domain-containing-protein
MVHQPASTGDVTSPAAEYQSSRLTVIDVHVLLVRDNDVLLTRRRHGDWDAMWHLPSGKLDPGESVLDAAAREAAEEVGVLIEQADLRHVHTVHVAGSGPAPRLGLFFETRKWVGEPVNCEPDKCSGVEWFPFDTLPDDVIPYPLAGIRAYRDGVDFGLLGWD
>NZ_CP014859.1|WP_157421182.1|4572393_4572657_-|hypothetical-protein
MAEQPENWIAGKANRTQGDALSYWTRERMLNAQPMPLETVEVGAEGPPEVILVSREELEARRTRSRRGTPPLDDSGEPVQPAGGAEF
>NZ_CP014859.1|WP_069850903.1|4571571_4572312_+|SDR-family-oxidoreductase
MATKELEGKKALVTGATSGIGRATSVRLAQEGATVYVTGRRADLGKETVALIEQAGGTGHFIAADVTKLDDITRLAHEVGDVDILVNNAATTSHTPVPEQDPAIYQQVFDVNVRAAYFFVAALAPQMVARGSGTIVNISSGGAVIGAPLGAVYNATKGAIDSLTRALAVEFGPQGIRVNAVAPGAIRTEKALDLMGETFEQLVPTLPLRRIGEPEEIAEAVLFLASDRATYITGSILRVDGGVTVV
>NZ_CP014859.1|WP_069850901.1|4569977_4571513_+|hypothetical-protein
MSLRFSLLGPVRAWRNEDEIPLGPRQQRAILAALLLNNRIRLSVGQLIGMVWDDPTPSAVMAVRTYVYKLRKLLPELDLTAKDGGYTIRTEIVDDEAGEPLEGLHSRYFDAQRLRLAQRGLKAKEDRLERELNTLELQRHVDEHPLREHPRALLMHTLYRDGRQAEALDQFHEARVLFAAELGIEPGPELREVHQAILDGTLKHVAKPDQLPLDFAEFTGRAREIAQLVAALPGPVGITGMQGSGKTSLAVRVAHAVKHDYPDGWFFVRGANVVDDLLRAVGVESASGDKAALWREKARGKRFLVVLDDIECAEQVHDLATPGSALIVTSVRRLNGIPGMTWVKIAGLESGEAREFFRALLGDARFDAELTQAEELLDRASCLPGPIRVAGSKLAARPHWTIDMLLQQADLGYRMGESIPSDCGAVLNPLAKAAQRLADHERRLLLVFAERGAKEITSMEATALSGCGLGVIEMTLEALADVHLIDPVVRGRYRLPTFVRSYFGATAATLA
>NZ_CP014859.1|WP_157421181.1|4569229_4569922_+|hypothetical-protein
MELCKRFADDVESLRRFDDAHLYHQITFAASLRHSRDEFLPHLAPDLDAVADVVLGRMSTGWFAQPTPGTPQSRFSKTGEFGPIGSLASHLGAEISEKPAGGAWTSSYLPSGESAWARWEQAEFSHESRDPWSVHFDASSCALYQIDSLDDFTRLVLRYPGDTQNGRVGIDWSTVAADFHAVHLTAKGLLTVQNFPVSTPLGIAELRGWDAESTVWLRVPPGLRVTPAND
>NZ_CP014859.1|WP_157421180.1|4568294_4568477_+|hypothetical-protein
MLKPWMEKRPDETDREVMHRRSRTCYYCPREDPTVNESIEHEKTHEVPVRRKPKDAPIED
>NZ_CP014859.1|WP_069850898.1|4567863_4568247_+|hypothetical-protein
MTIPCVITVGVRSLTTGPESLVLVADRPSKSVAVAVRGRGLAALTRRAAGVALATLITERPASAVEVPVIGRQHQIGKLRISILGPQAALTLTAGDAVVRHWNIAHRPELAAAMNRVVTHLTAETAA
>NZ_CP014859.1|WP_157421179.1|4567415_4567655_-|hypothetical-protein
MQRSSVQWAEWAAGIADGDDLGAATVAGIGEVGVTSAEGADIEEAHGEVSGKQDGQGGTGSFGPMRLTIAPHTATATEP
>NZ_CP014859.1|WP_069850895.1|4566266_4567112_-|helix-turn-helix-transcriptional-regulator
MSRVTRTPRARALGHSLRTLREQKGMSAREVGRRIGVHSNTISRYENATKVISVNEVSALLGAMECSPEERNHVLKLTEDIGRPNWYVSQSHIPDQMSTLIMYEQEAAAITAVSLVLIPGLLQTRDYARAVISPVVPASDPLVMSRMGRKDVLDRENPVRLTAVLDEAVLSRAVGGPAIMATQLRYLLRQVERGVVDVRVLPFSAGVHAAMSGPFDVLEFADASPIIYVESLARGEFVDEADDVNRFLATRDTVIGAAMNTADSAALIAARAELHAESEAS
>NZ_CP014859.1|WP_069853908.1|4575264_4575549_-|HPr-family-phosphocarrier-protein
MHRRRVKVAASSGLHARPAALLAKAAAAQGIPTTIAKVSDGVPGEPVDTASIIGLMTLGAHQGDEVEIAADEEAAVDALAELVSRDLDEDVVLR
>NZ_CP014859.1|WP_069850906.1|4575563_4577018_-|hypothetical-protein
MRIVAVTACPTGIAHTYMAAEALEQAAKAAGHEIQVETQGSAGSTPLSTTDIQAADAVIFAVDVGVQDRERFDGKPRVDATVKQAINGAAGLLDRAIAAAEQRSDEPAPASAPTDTDPDSPANTGFGTRLRQWLMTGVSYVIPFVAAGGLLIALSFAIGGYDITEAPPVTEQFDAGSLAGWAALANQVGTIAFDFLVPVLAGFIAFAMADRPAIAPGFVGGAIAVVVGAGFLGGLVAGFLAGAVVGALRKIAVPKALAGVMPVLVLPLVGTAVVGTLMFVVIGQPIAAVTLGLTDWLNGLAGVNAALIGLIVGTMIAFDAGGPVNKAAYTFAVGGLSTGSDTALELMAAVMAAGMVPPLALALAVTVRAKLFSPSERESARSAWLLGASFITEGVIPFAAADPLRVLPSIMLGSATTGALSMTFGSTLRAPHGGIFVLPLVGGPLLYLLAIAIGMVVSAGAVILSKQIGRVTTTTTTATPAVAQ
>NZ_CP014859.1|WP_069850908.1|4577014_4577473_-|PTS-sugar-transporter-subunit-IIA
MTEEPLISADLVDLELVDTDRRAVVRSLANRLVAAGRVTDLEQFLADVEAREQQMATGLEGGIGIPHCRSTAVTLPALAFGRSSAGVDFGAEDGPAKLIFLIAAPDGANAIHLTVLAALARRLMRAEFIQTLSTATDPEAVAAYVRGEVFAP
>NZ_CP014859.1|WP_069850909.1|4577469_4578414_-|1-phosphofructokinase
MIVTVTPNPSLDRTILVDDVVLGAVHRARQVRLDPGGKGVNVSRALAAAEVATLALLPSGGPDGSRLAELLAPESVPVVEVPIGAATRSNIAVVAADGTTSKFNEPGAELTKTELRALEAKAAELAGRADWLVSCGSLPHGCPDDLHARLLHAARRSGARVAVDTSGRPLALACAANPELISPNLAELAELAGHPLPTLGEVLDVALRLRKAGVGAVLVSLGEQGALLVEDAGTWHAVSEATVVRSTVGAGDATLAGFLLAGAAGPEALRTAVAYGTAAVEQVGTRMPRPKDLRTATVRVTEADPSSSLNGAAL
>NZ_CP014859.1|WP_069850911.1|4578410_4579172_-|DeoR/GlpR-transcriptional-regulator
MYGAERRQLLVQRARRDGRIDVMAASDELAVAPETIRRDLGALERQGLVRRVYGGAIPVERLDFEPGVPQRDATNAAEKERIARAAVDLLPPRGTVLFDAGTTTARLAGLLPSEAELTVVTNALPVANQLAPRSNCTLYMLGGRIRGTTLAAVESWALDVLAGLTIDVGFFGANGFSPQRGCTTPDAVEAAVKTAMIRACRKRVLLADHGKYGDDQFSRFAEIADIDVVVTDDGLDQAAVAALTEAGTEVVLA
>NZ_CP014859.1|WP_084643757.1|4579368_4580061_+|methyltransferase
MPAERVEQIRRWHARAYREARAALQQEQTFAYLGRTIVVPPQVMPITPVSHLLGEAVLAEVGAQDRVLDMGTGSGVNAVLAAASGADVLAVDINPHALAAARSNAVRNGVAARVTVRHSDVFEFVDGVFDVMVFDPPFRWFAPRDLLEAATTDENYGAMTRFFNQARDYLKPGGRLLVFFGSSGDLEYLHRLIEASGFHRTVLARHAIVKDGQQVDYVALRLAVAGHVAS
>NZ_CP014859.1|WP_069850912.1|4580194_4580737_+|dihydrofolate-reductase-family-protein
MAKMLYSVSMSLDGFIAGAGGDMSWLADFTGPDPTIANLIGDVGSLLVGRNTYDGDDPNKGTEGEGEAFGGGWSGQQFVLTHRIPENSPPDIHFVDDFETAVAKSKAAAGEKYVNILGADVARQCVAAGLVDEVLVFLVPVLIGDGVRLFDHPGGTSIRLERLSVSEGPESTNLWFRVVR
>NZ_CP014859.1|WP_069850914.1|4580793_4581621_-|SDR-family-NAD(P)-dependent-oxidoreductase
MARTIVITGGTDGIGAALATALARSGDRVVVLGTNEHKGGRLVADAGDSPGTITFVRADLSLTSSTRHVAAELAETHPRIDGLVLGARFFQTRRRITSDGFEHNFALSYLSRLLLADGLYESMARADRPVVVNISGPGQDTPIDWTDLQSARAYDGVRAMSVTGRYNDLLGVDFAQRHGGGPVRYVLLHPGTTSTAFAGEYDPPTADFIRRQQTTAKPAAAVVPPLRRLLDDPPAEPLSAFHLDTRIDLHNGLFSKVDAARLAAATAELLAAPPE
>NZ_CP014859.1|WP_069850915.1|4582034_4585310_+|S8-family-serine-peptidase
MRPRRVAGVVAIAAVTVGLTAVTGTAQVPGSSPHAATSDSAPHQTLTLITGDRLLVTSTGGRQLVTVLPAEGRESIAFQQTGDGDTLSITPIDALPLIDQGSLDPRLFQVSRLIEQGFGDSGPLPLIVSHTDDGARPLASTDVEVVRELSSINAVSLAVDENETAELWSRLTTENSTLAAGVERVWLNGRSRVLDEESNAQVGAPAAWEAGFSGEGATIAVLDTGYDAEHPDLTEVVVDAADFTGSSVGVTDINGHGTHVASTAVGTGAASDGAHRGVAPEADLLVGKVCGDDGWCPDDAVIAGMEWAAGNDVAAANLSLGGWATDGTDPLSEALNAITEQSGTLFVVAAGNNGGEVMVGSPAAADAALAVGSVTKDDEQSEFSSRGPRLGDHAVKPDITAPGSDIIGARAAGTMPDQPADEAYTTQSGTSMASPHVTGAAAILAAQHPEWQAAELKAALTGSAEPLPGLDTTEQGSGRLDVANAVTAQVHTDVSSLSFGLFAYPHDQGPQTKTVVYRNSGDEDTVLDLDLAPVDSDGTPAPAGLFTVDAEQITVPAGGEASVDVTVEPSAGDLLGYLGGTLTAVSADGTTRLATAVAASLEAESYDLTIEATDKSGEPATSANLQIVDRADSSNRFYATRIEPGVYGAQLPAGEYDVLAVLYGRSPENLRAVTYVSDMAVDVTADATISLDGTAGERMTVATERESVLATSSVYVDFSGHSSGVIGMGEADPVYVVASESDETSAGGLRFTYRPTLVSTAGAAEEHVYTLLFDELDGLPDSVDYSVIDEELAQVATRYRAQGVAASAEAGSLGIPAIDAGRSLAGGVVPTELPSERLEFFTPGDIDWMGSVFAPVGGMTSRYTDYPTAQDYQADWNAAPLGMSLALPDLRGNHRVGDRIAIHTGTFSPVDETYLAPGAPKGTLTLSRDGEVIGESAYAGFGEFDVPAGPGEYTVDLTAARDNAVFGTQATARWTFASDTAGDTPEPLPMMSVRPRGEIDDLGRAPAGDYSLILELEHLTGGTAAEATLEISYDDGDSWEAVPVEFSEGEAVVEITHPDGDGFASLRTTVTDTDGNTAEQTMIRAYGIVAG
>NZ_CP014859.1|WP_084643252.1|4585676_4588955_+|S8-family-serine-peptidase
MRRRKVAGIVAVATLTAGLTAVAGSAQVPGSSAHAATADAEGQQILTLITGDRLLVTSSGGRQTVTVLPAEKREGIAFHQTGEGDTLSVTPVDALPLVEQGTLDPRLFQVTQLLDQGFGDSGPLPLIVSHTEGAARTLASTDAEVVRELPSLNAVSLAVDEGEAAGLWSTLTAENSTLATGVERVWLNGRSRVLDEESNAQIGAPEAWEAGFSGDGATIAVLDTGYDAEHPDLDGMVVDAVDFTDSPVGPQDVNGHGTHVASTALGNGAASDGAHRGVAPEASLLVGKVCDDNGSCADDAVIAGMEWAAEQGVSAANLSLGGSPTSGTDPLSESLNTLTEQSGTLFVVAAGNNGDDFMVASPASADAALAVGSVTKNDEQSPFSSRGPRLGDQAVKPDLTAPGSDIIGARAEGVIPNLPADERYMAQSGTSMAAPHVTGAAAILAAQHPEWEAAELKAALTGSAEPLPGLDTTEQGSGRLDVANAIAAQVHTDVSSLGFGVIAYPHDQGPQTKTVTYRNSGSEDAVLDLSFAPVGSDGTAAPAGLFTLNAEQITVPADGETTVDVTVDPSVNELLDYVSGPLIAASADGTTRISTAVAATLEPESYNLTIEATEQSGAPVASASIQLVDHATGTLDYSAYQVAPGVFEARLPVGRYDVLGTYFETTEDGGSAMTYISDMAVDVTTDTTIAMDGTAGERLTVDTDRESVLATSSIFLHFGGEISGTIGLPESIPVYVVAPDDDDAGKGGLRFVYRPALVSTPDAAEEHLYSLLFDEPAGLPASVAYSVTDEELARVSTRYRAQGVSSSAHTATLGIPSADEGASLASSFIPTELPSERTEFFTPGDDIEWQGSVLAADGGMTNRYTDYPTAGDYEAEWNAAPLGMSLALPDLRGNQRVGDQISIHSGTFSPVDETYLAPAVPTGSMTLSRDGEIIGTSENAGYAVFDVPAGPGEYTVAITAARESAVLGTQADATWTFTSDTAGETPEALPMMSLRPRGEVDDLGRAPAGSYSLELELEHLTGGTAAEVTLEISYDDGETWESVPVELAEGRATVEVTHPEGAEFAALRTTVTDTDGNTAEQTMIRAYGIVAD

Crispr_ID: NZ_CP014859_14

• CRISPR_ID: NZ_CP014859_14
• CRISPR_location: 4628725-4628995
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP014859_14

Consensus_repeat	Method
GGAACACCCCCGCGTGCGCGGGGCAGAC	CRISPRCasFinder
CCCCGCGTGCGCGGGGCAGAC	CRT
GTCTGCCCCGCGCACGCGGGGGTGTTCC	PILER-CR

spacers of NZ_CP014859_14

>14.1|4628753|33|NZ_CP014859|CRISPRCasFinder
GTGATGCGTGCTCGCGGCCGGAGCCGGAGTGTC
>14.2|4628814|32|NZ_CP014859|CRISPRCasFinder
ACTCCAACGTCGGCAAGGTCGACATGAAGCGC
>14.3|4628874|33|NZ_CP014859|CRISPRCasFinder
CGCTCTGCAGGGACAACTCGGCTCCCGTGGTGA
>14.4|4628935|33|NZ_CP014859|CRISPRCasFinder
CCCGCGCTGCGTCGGACGGCTCACCCGCGCCCG
>14.5|4628753|40|NZ_CP014859|CRT
GTGATGCGTGCTCGCGGCCGGAGCCGGAGTGTCGGAACAC
>14.6|4628814|39|NZ_CP014859|CRT,PILER-CR
ACTCCAACGTCGGCAAGGTCGACATGAAGCGCAGGAACA
>14.7|4628874|40|NZ_CP014859|CRT
CGCTCTGCAGGGACAACTCGGCTCCCGTGGTGAGGAACAC
>14.8|4628935|40|NZ_CP014859|CRT
CCCGCGCTGCGTCGGACGGCTCACCCGCGCCCGGGAACAC
>14.9|4628881|33|NZ_CP014859|PILER-CR
CGCTCTGCAGGGACAACTCGGCTCCCGTGGTGA
>14.10|4628942|33|NZ_CP014859|PILER-CR
CCCGCGCTGCGTCGGACGGCTCACCCGCGCCCG

CRISPR arrays and Neighbor proteins around NZ_CP014859_14

CRISPR arrays

The CRISPR arrays of NZ_CP014859_14

>merge|NZ_CP014859|14|4628725-4628995|CRISPRCasFinder,CRT,PILER-CR
ATGGGTGCCCCGCGTGCGCGGGGCAGACGTGATGCGTGCTCGCGGCCGGAGCCGGAGTGTCGGAACACCCCCGCGTGCGCGGGGCAGACACTCCAACGTCGGCAAGGTCGACATGAAGCGCAGGAACACCCCGCGTGCGCGGGGCAGACCGCTCTGCAGGGACAACTCGGCTCCCGTGGTGAGGAACACCCCCGCGTGCGCGGGGCAGACCCCGCGCTGCGTCGGACGGCTCACCCGCGCCCGGGAACACCCCCGCGTGCGCGGGGCAGAC

>NZ_CP014859|14|14|4628725-4628995|CRISPRCasFinder
ATGGGTGCCCCGCGTGCGCGGGGCAGAC	GTGATGCGTGCTCGCGGCCGGAGCCGGAGTGTC
GGAACACCCCCGCGTGCGCGGGGCAGAC	ACTCCAACGTCGGCAAGGTCGACATGAAGCGC
AGGAACACCCCGCGTGCGCGGGGCAGAC	CGCTCTGCAGGGACAACTCGGCTCCCGTGGTGA
GGAACACCCCCGCGTGCGCGGGGCAGAC	CCCGCGCTGCGTCGGACGGCTCACCCGCGCCCG
GGAACACCCCCGCGTGCGCGGGGCAGAC

>NZ_CP014859|14|9|4628732-4628995|CRT
CCCCGCGTGCGCGGGGCAGAC	GTGATGCGTGCTCGCGGCCGGAGCCGGAGTGTCGGAACAC
CCCCGCGTGCGCGGGGCAGAC	ACTCCAACGTCGGCAAGGTCGACATGAAGCGCAGGAACA
CCCCGCGTGCGCGGGGCAGAC	CGCTCTGCAGGGACAACTCGGCTCCCGTGGTGAGGAACAC
CCCCGCGTGCGCGGGGCAGAC	CCCGCGCTGCGTCGGACGGCTCACCCGCGCCCGGGAACAC
CCCCGCGTGCGCGGGGCAGAC

>NZ_CP014859|14|11|4628786-4628995|PILER-CR
GGAACACCCCCGCGTGCGCGGGGCAGAC	ACTCCAACGTCGGCAAGGTCGACATGAAGCGCAGGAACA
CCCCGCGTGCGCGGGGCAGACCGCTCTG	CAGGGACAACTCGGCTCCCGTGGTGAGGAACAC
CCCCGCGTGCGCGGGGCAGACCCCGCGC	TGCGTCGGACGGCTCACCCGCGCCCGGGAACAC
CCCCGCGTGCGCGGGGCAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069850968.1|4630671_4631280_-|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223728
NZ_CP014859.1|WP_069853916.1|4632938_4634159_+|glycosyltransferase	unknown	unknown	gnl|CDD|340830
NZ_CP014859.1|WP_157421438.1|4629156_4629351_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069850977.1|4637272_4638901_+|carbamoyltransferase	unknown	unknown	gnl|CDD|225103
NZ_CP014859.1|WP_069850960.1|4625456_4626401_+|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176191
NZ_CP014859.1|WP_069850962.1|4626518_4627262_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235500
NZ_CP014859.1|WP_069850959.1|4623322_4624144_+|DUF1684-domain-containing-protein	unknown	unknown	gnl|CDD|377941
NZ_CP014859.1|WP_084643763.1|4624388_4625249_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP014859.1|WP_069850967.1|4629750_4630611_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235853
NZ_CP014859.1|WP_069850955.1|4620648_4621542_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_CP014859.1|WP_069853917.1|4635060_4635966_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NZ_CP014859.1|WP_069850963.1|4627366_4627960_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP014859.1|WP_069853914.1|4621574_4622396_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
NZ_CP014859.1|WP_069850965.1|4628121_4628595_-|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NZ_CP014859.1|WP_157421439.1|4631949_4632906_+|glycosyltransferase	unknown	unknown	gnl|CDD|223515
NZ_CP014859.1|WP_069850974.1|4634191_4635088_-|glycosyltransferase	unknown	unknown	gnl|CDD|133029
NZ_CP014859.1|WP_157421186.1|4636136_4637153_+|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|187541
NZ_CP014859.1|WP_069850970.1|4631276_4631723_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069850954.1|4619701_4620652_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NZ_CP014859.1|WP_069850957.1|4622392_4623232_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069850968.1|4630671_4631280_-|NAD(P)H-dependent-oxidoreductase	gnl|CDD|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	7.87137e-12
NZ_CP014859.1|WP_069853916.1|4632938_4634159_+|glycosyltransferase	gnl|CDD|340830	cd03800, GT4_sucrose_synthase, sucrose-phosphate synthase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.	1.67313e-153
NZ_CP014859.1|WP_157421438.1|4629156_4629351_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	6.2914e-17
NZ_CP014859.1|WP_069850977.1|4637272_4638901_+|carbamoyltransferase	gnl|CDD|225103	COG2192, COG2192, Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones].	2.25317e-166
NZ_CP014859.1|WP_069850960.1|4625456_4626401_+|NADP-dependent-oxidoreductase	gnl|CDD|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	8.53785e-79
NZ_CP014859.1|WP_069850962.1|4626518_4627262_-|SDR-family-oxidoreductase	gnl|CDD|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	9.50503e-79
NZ_CP014859.1|WP_069850959.1|4623322_4624144_+|DUF1684-domain-containing-protein	gnl|CDD|377941	pfam07920, DUF1684, Protein of unknown function (DUF1684). The sequences featured in this family are found in hypothetical archaeal and bacterial proteins of unknown function. The region in question is approximately 200 amino acids long.	6.68389e-42
NZ_CP014859.1|WP_084643763.1|4624388_4625249_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	8.71775e-58
NZ_CP014859.1|WP_069850967.1|4629750_4630611_+|SDR-family-oxidoreductase	gnl|CDD|235853	PRK06701, PRK06701, short chain dehydrogenase; Provisional.	7.32482e-142
NZ_CP014859.1|WP_069850955.1|4620648_4621542_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.58507e-81
NZ_CP014859.1|WP_069853917.1|4635060_4635966_-|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	7.04539e-24
NZ_CP014859.1|WP_069850963.1|4627366_4627960_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.48403e-09
NZ_CP014859.1|WP_069853914.1|4621574_4622396_+|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.98737e-114
NZ_CP014859.1|WP_069850965.1|4628121_4628595_-|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	6.23093e-20
NZ_CP014859.1|WP_157421439.1|4631949_4632906_+|glycosyltransferase	gnl|CDD|223515	COG0438, RfaG, Glycosyltransferase [Cell envelope biogenesis, outer membrane].	6.04762e-10
NZ_CP014859.1|WP_069850974.1|4634191_4635088_-|glycosyltransferase	gnl|CDD|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.20201e-28
NZ_CP014859.1|WP_157421186.1|4636136_4637153_+|GDP-mannose-4,6-dehydratase	gnl|CDD|187541	cd05230, UGD_SDR_e, UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs. UGD catalyzes the formation of UDP-xylose from UDP-glucuronate; it is an extended-SDR, and has the characteristic glycine-rich NAD-binding pattern, TGXXGXXG, and active site tetrad. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.6229e-154
NZ_CP014859.1|WP_069850954.1|4619701_4620652_+|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.2988e-104
NZ_CP014859.1|WP_069850957.1|4622392_4623232_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	5.80769e-104

Protein sequences

>NZ_CP014859.1|WP_069850965.1|4628121_4628595_-|carboxymuconolactone-decarboxylase-family-protein
MEHRFDLLKNQGSAKSLRHLVAAGKATLESTVPPETQELVRIRVSQINSCAFCTDMHIKEALHAGEDAQRLHLVSVWRDANVFTEAERAALELAEQGTRIADAAGGITDDAWANAAKHYDEEQLAALAALIAVMNAFNRMNVIAGNPGGDYQVGQFR
>NZ_CP014859.1|WP_069850963.1|4627366_4627960_+|TetR/AcrR-family-transcriptional-regulator
MPRPRKFDEQAVLAAAQALFWRKGYADTSIQDLTEATGLRPQSLYGAFGNKHELFLRILDDYRAWQSSELEAALAANPSPWNGLLQAVTFDSSESLALPPQGCLMASSVSALSAKDEQVRQRAIESFDQALALFTRQIIRAQECGEVNDDLDAEQAARTLISIRFGIEALHKSGIDEAELRRVKTAAVQMIERSVAR
>NZ_CP014859.1|WP_069850962.1|4626518_4627262_-|SDR-family-oxidoreductase
MTARTLEGKTALVTGGSRGIGAGIVARLAAEGANVAFTYASSKQRAESVASAAIEAGGIAHAIHADSMREQDVADAVTATVDRFGGLDILVNNAGGGVFKAIEDLTMAEIDTMLTVNVRSVVVAIRESLPHLGEGGRIINIGSVNAVRNPFPGLSVYAMTKGAIASLTNGLAKELGARGITINNLQPGPVDTEANPADGPNASNLLTAMSTDRFGTVAEISAFVSYLAGPDAGYITGANLNIDGGFV
>NZ_CP014859.1|WP_069850960.1|4625456_4626401_+|NADP-dependent-oxidoreductase
MKAIGVYRYGGPEALHVLDLPEPQAGPGEVRIRVHAAAVSATDVLLRTGGHAVRMPDRQPPFVPGMDAAGIIDQLGPEVDGRLWVGQRVIAMVLFVGPHGGAYAEQVVVPAASVVPAPKDADFPAASTVLMNALTARLALDELSLSPGDTVAVTGAAGAVGGYAVELARSDGLSVIADAAERDVDLVRGFGADRVVERGPEVAAGIRALVPEGVRGVVDGSLQTAELLPALTDGGTLVELRGWSGPAERGIRVRPLMVTAGMEDTAKLDALRRQVDDGTLTLRVAEVLPAEEAATAHRLVEAGGLRGRVVLDFS
>NZ_CP014859.1|WP_084643763.1|4624388_4625249_+|IclR-family-transcriptional-regulator
MAASADRPDEARQADGAAEAKPEERPGGVRDVKSAARTLELLELLAARQNRPARLRELSEALGMPRSSCYALLRTLAKYGWVRTDTSGTMYGIGIRALIAGTSYLDTDPYLRIAKPVLDHLGEQLDETFHFGRLDGTDVVYLATRESGQYLRPYSRVGRRLPAYSTSLGKALLAERDEHELGEHLPEVMTPLTPHTLTDRAALTEELTKVRERGYAVDQQENSVGLHCVALPMRYATPALDAISCSVPLARLTPAREADIIAAMRRAREEMERSATSVAMGIAGGI
>NZ_CP014859.1|WP_069850959.1|4623322_4624144_+|DUF1684-domain-containing-protein
MTQTVRDETAEREAWNAWREARRRRVIGAEGDLALVDTHWPETDSRFAELPGAWSVRDDAVWLTATEQDGIHTRDGKPVIGELQVSAGEKPAPMLRFAGGSATVVRRGEQFGIRRFDPQAVAIDEFEAIEAFDFAAAWHIPATFTKFATDTTVNYEKMLEDEPVETAVPGELRFTVAGQEYVTTPMISGGRLMLVFADATTGVSSYQPGRFVLLDLPASTPGEAVPVTIDFNRAYLPPCAFSAHYNCPLPPSGHRIAVSVEAGEKLIARKAAE
>NZ_CP014859.1|WP_069850957.1|4622392_4623232_+|ABC-transporter-ATP-binding-protein
MTEHTEPAAPLWEARGLTRRFRAPSGNRRGGAGLRTALSEVDLTVREGEALGIVGESGAGKSTLLRLLLGLDRPDAGELHYRGAPLGTSRRALRDFRRDVQVVFQDPRGSLNPRMRVSSIVAEPLRSLRIPGDHQARVREVLAEVGLGADAATRFPHEFSGGQRQRIAIARALAPRPKVLVGDEPVSALDVSVRAQILDLLGTLADQHAMTLVLVSHDLAVVGRLCPRVLVLNQGRVVETGPTEQVYSTPTQDYTRRLLAAVPRLPEGTLSGAADRSTA
>NZ_CP014859.1|WP_069853914.1|4621574_4622396_+|ABC-transporter-ATP-binding-protein
MGLLRVRGLTVRRRDGHPLVEDIDLDLAAGDRLGLVGESGSGKSLTALAVAGLLPEGMTATGSVQLDGVELLGLAEAELAKVRGSGVAMVFQEPLTALDPLMRVGRQIASGLRRHRGLTGRQAEAEAVELCRRVRLPDPEESARAYPHQLSGGQRQRVGLAIALACGPRLLIADEPTTALDVTVQAEILDLITESVAAEGAGLLFISHDLPVIATVADRIAVMRDGGIVEHGDLHPVLADPEHPYTRELLTAALAAGRLPGDPVPDDSSGEAR
>NZ_CP014859.1|WP_069850955.1|4620648_4621542_+|ABC-transporter-permease
MSPALRSKPGGAEPTASTAAARVRARTSRRRGPSLIAGAVLVGLVVLAALVSLVWTPFDYDATGAGGRLETPSGTHWMGTDRLGRDVFSQFLVGARLALGIGAASVLIAAVVGVSLGLLAALAPRKADDAVVHGIDVLIAFPTLLLAMVLVAVRGASTFTAVLAIGLATSAVVARLTRIAARRVLVQDYVLAATASGTGRLGILLRHVLPNIYPILLVQLSLEFGLAVVAEASLSYLGLGSPPPNPSWGQMLRDAQAVLGVQLWPALFPGLAIVITVLGLNLLGDGLREYADPELSR
>NZ_CP014859.1|WP_069850954.1|4619701_4620652_+|ABC-transporter-permease
MIRYVLRRVLLLAASLLAASALTFLLLSTLPGNPARTMLGVEATEEQVAELSRQLGTDQPTPIRYLNWLGDLLTGDLGQSYASGQPVGPEILSRMAVTLPLGLSAFVLSVLIAVPLGVWAALRHRSVVGLVVSAISQLGVAVPIFWVGIMLVAVFALNLGWAPPGGFPVAGWAEPVAALQSLVLPVITLAVAQASSLLRYVRSATLDVVNQDFLRTARSVGLTRSQALWRHGLRNASVPVLSILGVQLAGSLLGAVIVESVFTLPGLGRMLLTDVGNRDLVKVQATVFLMTSVVLIVGFAVDVAQRAVDPRLRAAR
>NZ_CP014859.1|WP_157421438.1|4629156_4629351_-|DUF397-domain-containing-protein
MGLEAADWRKSSRSTGTNGGCVEIGHASGLVGIRDTKNRAGGTLSVSGTAFGSLILAIKEGNLR
>NZ_CP014859.1|WP_069850967.1|4629750_4630611_+|SDR-family-oxidoreductase
MTGPGGEQPRQQQRPPGVTKDMDPQPRDSMADYEGRGLLTDKRALITGGDSGIGRAVAVAFAKEGADIAIAYLNEHDDAERTAELVRAEGKRCVLLPGDLAGAAHCRDIVANTVQQLGGLEILVNNVATQWPLDAPEDLTEEQWLHTFDVNIHSYFRVTSAALPHLGDGAVIVNTGSVNGLRGNKSLIDYSATKGAIHAWTFSMAQALASRRIRVNCVAPGPVWTPLIPSTFPPEKVKEFGLQVPFAEAAHPADLAPSYVFLASNRLSGYYSGEVIAALGGETTPG
>NZ_CP014859.1|WP_069850968.1|4630671_4631280_-|NAD(P)H-dependent-oxidoreductase
MSDIHALALVCSLKASPAPSSSELLAKQVLEQLATHKVTGESIRVADHDVRPGVETDMGEGDAWPEIRRKIAKADILLLATPTWLGHPSSIAQRVLERLDAALSDTDDQSRPAMFGKVALAAVVGNEDGAHKIIADVFQALNDIGFSIPAQGSTYWNSEAMKPVDYQDLDSTPAAVASTNATAARNAAHLARLLKTNQYPAG
>NZ_CP014859.1|WP_069850970.1|4631276_4631723_-|hypothetical-protein
MGSDDQTTPAVSRLLAEFDFDPRLRRPLAALGISPSTAVLLLDETGLKVRFGLWRLQTPLANLRSATVGGPFQLFKVAGVRLSAADRGLTFGTGPGPGVCIRFHRPVSAIEPFGIVRHPGLTVTVVDPAALADRVNRLHEPTSKRSAS
>NZ_CP014859.1|WP_157421439.1|4631949_4632906_+|glycosyltransferase
MRVLLWHVHGSWTDSFVRGPHRCLLPTVEGGGEWGRGRCGRDWRSAVEVPVTEIRESQPDVVILQRPQELDLVEQWLGRRPGKDIPAVYVEHNVPRADPVSARHPMADRPDIPIVHVTHFNDLMWDNGRAPTRVIDHGIVDPGDHYTGELPHGVALINEPTRRARVTGSDLLPMFAEAGPIDLYGIGAREFDTRQRGTHPVHGIDDLPHHRLHPEMARRRVYLHTARWTSLGLSLLEAMHLGMPVVSLAATEAPMAVPAEAGAVSTDISVLVRAFHELLHEPDLAVLAGKAAREYALTRYGLDRFLRDWSALLDEVVR
>NZ_CP014859.1|WP_069853916.1|4632938_4634159_+|glycosyltransferase
MRIAMISEHASPLAALGGVDAGGQNVHVAELSAALCRQGHQVTVYTRREDPLVPEVVVTQPNCRVVHVPAGPARPLPKDLLLPYMGEFAAFLRAQWSVEPPDVVHGHFWMSGLAAMLAVVGTEIPVVQTFHALGAVKRRYQGAEDTSPPERIPVEKLLAQQVAHIIATCSDEVLELADLSVDGSRASVVPCGVDVDRFSPIGPRARLTEAHRIVSVGRLVPRKGFDIAVAALAELPNTELVLAGGPDDGRLDEDPEAGRLRGLATELGVGDRLRMLGQVPRGDMPGLFRSADVVVCTPWYEPFGITPLEAMACGVPVVSASVGGLMDTVVDGVTGTLVKPRDPAELAAAVWDLLADPSRRRRYGLAGRQRVREGYCWDRVAEETLRAYRLVCAPSTEGIGGGQAVV
>NZ_CP014859.1|WP_069850974.1|4634191_4635088_-|glycosyltransferase
MGGDRITLVIITCDRREQLLETLAQVTALPDAAPIVLVDNASSDGTADAVAAAYPQVELIRADRNLGSLARNVAVRRIDTPYVAFCDDDTRWQPGALTRAVTLLDRHPGLASVTGRCLVEPELAEDPLTPELRASPVRGPKWLPGPALLGVMAGLSAFRVSAFRQVGGFSSRMWLGGEEELLALDLAARGWWMCWVEDMVIHHAPSRVRNARRRRQLGIRNTLWTLWLRRPLRSVLRRSLVVLRSAPADRATLKAVLEALRGLPWVLRERQVVPVSVELGLMRLEAQQRRSSARRYVG
>NZ_CP014859.1|WP_069853917.1|4635060_4635966_-|glycosyltransferase-family-2-protein
MSEPRTTVVIATRNRAGELRHTLARLRALRPTPPIIVVDNASTDATAAAVAEVAGVRLIRLPANRAAAARNLGVVAATTPYVAFSDDDSWWAADALPAAERLLDAHPSVGLLAARTLVGPGDTEDPINTLLATSPLGHQSELPGPSVLGFLACAAIVRRTAFLRVNGFSRLLHFGAEERLLALDLAADGWDLCYAAELRAHHHPSTNRPPSAWRKDLERRNNTLIAWMRRPLPRVAAETRLLLREGDRRQRSRIVAGLLRRLPSALWQRHRLPAEVERRVRVLERAEERSRQPWAATASPS
>NZ_CP014859.1|WP_157421186.1|4636136_4637153_+|GDP-mannose-4,6-dehydratase
MEVPACGPLWGRVIAGVTRRIERALVTGGMGFVGSHLCELLLAEGSEVLILDNLVTAAPGTVAEFGNRPNLRVDRQDVTEPITTPGPFDVVFHLASAASPQDYLRLPIETLRAGSLGTTHALDVALRDGARFVLASTSEVYGDPAEHPQRESYWGHVNPIGPRSVYDEAKRYAEALTNAYRGHRGANTGIARIFNTYGPRMRPDDGRMVPTFIRQALAGLPMTVTGDGAQTRSLCYVADTARGLLALGRSDHPGPINLGNPVELSVGDLAAEVRSAAGSESPVTFVEAAEDDPRRRCPDITLARRQLSWRPEVALADGLRRTIDWFEENTGIRAAHPA
>NZ_CP014859.1|WP_069850977.1|4637272_4638901_+|carbamoyltransferase
MRILGVNAVFHDPAAALVVDGHIVAAAEEERFSRRKHGKSPVPFSTWELPEQAIAWCLHRAGLRPDQLDAVGYSYDPDLVDHSLGGLDPGSEELRTDYVRRAPAFLRSAMPGLDPSIVRFVRHHVAHAASAALAAPFGDCAVLVADGRGESTSYVAGEYRDGKFTEHAAQQLPHSLGLLYEDLTEHLGFARSSDEYKIMALASYGKPRFLDRFRELAYPTGDGGFHTDPVSWTEFAPARHGSDTELDSAHADLAASVQRRIEEVWLDLATWLHDRTGAKNLALAGGIALNCVANTRLYAEGPFDQVWVQPASGDAGTALGAALQLSADLGEPTGPMPGADLGREWSDDEIEEILRVARVRYERPADVAVEVAQALADDQVVAWFQGRAEFGPRALGHRSLLAHPGPTANLGRLNDVKGREQFRPVAPMVLADRAAEIFTRGPLPSPYMLFVHDVAADWRDRIPTVTHVDGTARVQTVAPQHTPLLARMLREFEARTGLPVVVNTSLNTAGRPMVDSPRDALECFGSAPVDLLAIGPFVVRRS

Crispr_ID: NZ_CP014859_15

• CRISPR_ID: NZ_CP014859_15
• CRISPR_location: 4912556-4913036
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: csa3,DEDDh

Consensus repeat of NZ_CP014859_15

Consensus_repeat	Method
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	CRISPRCasFinder
GTTGCGATCCTCACCGGCCCCGNAGGGCCGGTGCCAC	CRT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	PILER-CR

spacers of NZ_CP014859_15

>15.1|4912593|37|NZ_CP014859|CRISPRCasFinder,CRT
AGGACGTCACCCCGTCGGCGGCCAGAGCGTGCCCGAT
>15.2|4912667|38|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
TGTCCGTCGTGCGCTCAGCCGGTGGGGCAGCAGTGCGT
>15.3|4912742|37|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
GACCGCCATCCGACGACCGCCAAACGGCAGTAAAATC
>15.4|4912816|38|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
CCGCCGGTGGCCGAGCGGTATCCGTGGCGGGGGAGCGC
>15.5|4912891|37|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
GCGGATCGGGGCCGCCTGGTCGATGGCGGCCAACAGG
>15.6|4912965|35|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR
AGGCTGGCACCGTTCATATCGGAGAGGTCGATGGT

CRISPR arrays and Neighbor proteins around NZ_CP014859_15

CRISPR arrays

The CRISPR arrays of NZ_CP014859_15

>merge|NZ_CP014859|15|4912556-4913036|CRISPRCasFinder,CRT,PILER-CR
GGTGCGATCTCCACCGGCGCTGAAGGGCCGGTGACACAGGACGTCACCCCGTCGGCGGCCAGAGCGTGCCCGATGTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCACTGTCCGTCGTGCGCTCAGCCGGTGGGGCAGCAGTGCGTGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCACGACCGCCATCCGACGACCGCCAAACGGCAGTAAAATCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCACCCGCCGGTGGCCGAGCGGTATCCGTGGCGGGGGAGCGCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCACGCGGATCGGGGCCGCCTGGTCGATGGCGGCCAACAGGGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCACAGGCTGGCACCGTTCATATCGGAGAGGTCGATGGTGTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCAC

>NZ_CP014859|15|15|4912556-4913036|CRISPRCasFinder
GGTGCGATCTCCACCGGCGCTGAAGGGCCGGTGACAC	AGGACGTCACCCCGTCGGCGGCCAGAGCGTGCCCGAT
GTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCAC	TGTCCGTCGTGCGCTCAGCCGGTGGGGCAGCAGTGCGT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	GACCGCCATCCGACGACCGCCAAACGGCAGTAAAATC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	CCGCCGGTGGCCGAGCGGTATCCGTGGCGGGGGAGCGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	GCGGATCGGGGCCGCCTGGTCGATGGCGGCCAACAGG
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	AGGCTGGCACCGTTCATATCGGAGAGGTCGATGGT
GTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCAC

>NZ_CP014859|15|10|4912556-4913036|CRT
GGTGCGATCTCCACCGGCGCTGAAGGGCCGGTGACAC	AGGACGTCACCCCGTCGGCGGCCAGAGCGTGCCCGAT
GTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCAC	TGTCCGTCGTGCGCTCAGCCGGTGGGGCAGCAGTGCGT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	GACCGCCATCCGACGACCGCCAAACGGCAGTAAAATC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	CCGCCGGTGGCCGAGCGGTATCCGTGGCGGGGGAGCGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	GCGGATCGGGGCCGCCTGGTCGATGGCGGCCAACAGG
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	AGGCTGGCACCGTTCATATCGGAGAGGTCGATGGT
GTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCAC

>NZ_CP014859|15|12|4912630-4913036|PILER-CR
GTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCAC	TGTCCGTCGTGCGCTCAGCCGGTGGGGCAGCAGTGCGT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	GACCGCCATCCGACGACCGCCAAACGGCAGTAAAATC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	CCGCCGGTGGCCGAGCGGTATCCGTGGCGGGGGAGCGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	GCGGATCGGGGCCGCCTGGTCGATGGCGGCCAACAGG
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCCAC	AGGCTGGCACCGTTCATATCGGAGAGGTCGATGGT
GTTGCGATCCTCACCGGCCCCGAAGGGCCGGTGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069851310.1|4901459_4902485_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380516
NZ_CP014859.1|WP_084643308.1|4913744_4914377_+|SRPBCC-domain-containing-protein	unknown	unknown	gnl|CDD|176908
NZ_CP014859.1|WP_157421208.1|4903614_4904745_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069851332.1|4914643_4915132_+|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176854
NZ_CP014859.1|WP_069851328.1|4913339_4913729_+|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP014859.1|WP_069851312.1|4902728_4903271_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|376829
NZ_CP014859.1|WP_157421446.1|4909411_4909978_-|TIGR03086-family-protein	unknown	unknown	gnl|CDD|274424
NZ_CP014859.1|WP_069851334.1|4915516_4917334_-|hypothetical-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|176648
NZ_CP014859.1|WP_172803921.1|4925417_4927475_-|S9-family-peptidase	unknown	unknown	gnl|CDD|224423
NZ_CP014859.1|WP_084643790.1|4911472_4912291_+|pectate-lyase	unknown	unknown	gnl|CDD|367395
NZ_CP014859.1|WP_069851339.1|4920145_4921069_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069851320.1|4905705_4907754_-|beta-galactosidase	unknown	unknown	gnl|CDD|367090
NZ_CP014859.1|WP_069851324.1|4910145_4911000_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NZ_CP014859.1|WP_157421210.1|4919385_4920039_+|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|223736
NZ_CP014859.1|WP_069851343.1|4923339_4925127_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069851341.1|4921068_4923081_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069853967.1|4907881_4909231_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP014859.1|WP_069851314.1|4903267_4903597_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_157421209.1|4904826_4905663_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_172803850.1|4918452_4919091_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014859.1|WP_069851334.1|4915516_4917334_-|hypothetical-protein	DEDDh	cd06127_DEDDh_CAS-I	1e-37	124.5	0.0
NZ_CP014859.1|WP_069851328.1|4913339_4913729_+|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	1.1e-14	49.6	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069851332.1|4914643_4915132_+|SRPBCC-family-protein	gnl|CDD|176854	cd07812, SRPBCC, START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket; they bind diverse ligands. Included in this superfamily are the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, and the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), as well as the SRPBCC domains of phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of this superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.58597e-19
NZ_CP014859.1|WP_172803921.1|4925417_4927475_-|S9-family-peptidase	gnl|CDD|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	5.41791e-70
NZ_CP014859.1|WP_084643308.1|4913744_4914377_+|SRPBCC-domain-containing-protein	gnl|CDD|176908	cd08899, SRPBCC_CalC_Aha1-like_6, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	1.28778e-32
NZ_CP014859.1|WP_069851312.1|4902728_4903271_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	7.30245e-12
NZ_CP014859.1|WP_157421446.1|4909411_4909978_-|TIGR03086-family-protein	gnl|CDD|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	5.88394e-28
NZ_CP014859.1|WP_069851334.1|4915516_4917334_-|hypothetical-protein	gnl|CDD|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	5.84025e-43
NZ_CP014859.1|WP_084643790.1|4911472_4912291_+|pectate-lyase	gnl|CDD|367395	pfam03211, Pectate_lyase, Pectate lyase.	4.4592e-88
NZ_CP014859.1|WP_069851320.1|4905705_4907754_-|beta-galactosidase	gnl|CDD|367090	pfam02449, Glyco_hydro_42, Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.	0
NZ_CP014859.1|WP_069851324.1|4910145_4911000_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.29706e-19
NZ_CP014859.1|WP_157421210.1|4919385_4920039_+|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	3.15905e-31
NZ_CP014859.1|WP_069851328.1|4913339_4913729_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.76178e-16
NZ_CP014859.1|WP_069853967.1|4907881_4909231_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	6.11736e-37
NZ_CP014859.1|WP_069851310.1|4901459_4902485_+|substrate-binding-domain-containing-protein	gnl|CDD|380516	cd06293, PBP1_LacI-like, ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.62171e-106

Protein sequences

>NZ_CP014859.1|WP_084643790.1|4911472_4912291_+|pectate-lyase
MWSSRASSKRPRSVLAALVTLPLAAAALVLSPALGTAEPTAATAPAPLTALDEPVSETIELDEDFDGGGTRYYGEGDLGEGGQNEGGDPLFELADGVTISNVILGSPAADGIHCQGSCTLRNITWEDVGEDAATFRADSDSAQFRVEGGSAAQAEDKVFQHNGPGTLTVSNFEVEDFGALYRSCGNCSSMYERHVVLEDITVRTPGDRLVGINENYGDTATLSNITIIGDDGQDITICQRYEGNDNGDEPEETGEGPDGQHCLYEESDISYQ
>NZ_CP014859.1|WP_069851324.1|4910145_4911000_+|helix-turn-helix-transcriptional-regulator
MASTIGRGRNLGVLYEAAARQHFQLGKHAPAPEIAPFVEYYWTIHWNLPGDRSHRQWVIPHPTVHLVFDPAGSTVNGVMRGRFSRLLSGSGRVLGIRFRPGGFRPFLDGPVSQLTDRVIPLAEFLDTEAEEQARRALDIVEPAAMVASADEFLRPRLPAVDPMVAVVADLVRQIVDEPDLARVDTLADRVGMGRRTLQRLFAEYVGVSPKWVLLRARVHEAALRADEDAVDWASLAADLGYSDQAHLTRDFARVVGVSPARYARGCRRDASAERLRKPGTAIRE
>NZ_CP014859.1|WP_157421446.1|4909411_4909978_-|TIGR03086-family-protein
MATAAATLRDLSDGIDAEQLAAPTPCTEFDVRKLLDHVIWATRILTAAAAKQPLPADTDWTADLMDDQWRSRLADGLAGTAAAWDDPAAWAGTTVLGPGTELPATLVGELTFVEFVLHGWDLAKATGRTYDCSPETAAAALEVLQKLYAQTQGLSSLAFGPEIAVDSDADAFDRALGLSGRDPGWTAG
>NZ_CP014859.1|WP_069853967.1|4907881_4909231_-|Gfo/Idh/MocA-family-oxidoreductase
MDEEWCRVSEDSTPVRYAVVGLGSRAEMYVDALATRFPEHAELVALCDSNPTRMQVHNARLAGQLGVAAVPTYAPADFSEMLTRERVDAVMVCTTDSSHDDYLVATVEAGLRAVTEKPMTTDVDKARRILEAQERTGGRIEVTFNYRYNPVHQRVRELLADKVIGDVGSVHFEWLLDVQHGADYFRRWHRNREHSGGLLVHKSSHHFDLVNWWLGDAPDSVIGLGNLFFYGAAGGARNGYAKDYDRAAGSEAAATDPFALDMAASPRLKELYLDAEHEDGYQRDRNVFAADIDIEDDMSVLARYRGGASLTYQLTAYAPYEGYRVSFNGTKGRLELDVLENDYARSPLEHGSRMGISPGAVEEAVPTRTAITVRPLFKPAEVVLDEPMRPGHGGGDELMLDALFGPAAADPLGLRADHIAGARALAIGLAATKSFGTGGLVRISDLLPI
>NZ_CP014859.1|WP_069851320.1|4905705_4907754_-|beta-galactosidase
MGKDLTALRSRLGGPAYGCDYNPEQWPEEVWAEDMRLMRQAGVNLVSVGIFSWAKIEPRPGEYDFGWFDRLMDLLAANGIGACLATMTASPPPWLARLHPETLPITATGVRLAPGSRQQFCPSSPVYRDHARRLVEQIATRYRDHPALALWHVNNEYGCHMNACYCEVSAAAFREWLRDRYGDLATLNAAWYTDFWSQQYGEWDEIGVPSLAPYHPNPTQSIDFSRFTSDAFLGCFRTEKEVLSRLTPEVPVTTNFIHEGPAIDLFGWAEDQDLIAFDSYPDPFEADSHIAAGFHYDLMRSLRHGQPWFLMEQATAAVNWRERNAMKAPGAMRLGSWQAVAQGADAVMFFQWRASRGGTEKFHAAMVPHTGTDTRIFREVCELGAELAAVPGLVDSRVHADTALLLDWSSWWALERDSHPSVDVTRGEAELAHYAPLFEAGVTCDVVHPERDLSGYRLVVVPNLYLMTESVAERLLAYVRGGGHLVVSFFSGIVDENDHIHPGGMAPALRETLGVWVEEFWALPEAGTVAVTGLAGSDSTGTGRIWSEVIRLEGAQSLAEFAEGELVGSPAVTRHQLDSGVAWYLGTRLDAATMRGLLDRVRGEAGVAPDLAVPPGVQAVTRHAEDGTRFLLLLNHGDEPAEITLDQPMVDLLAGVTEPDRESSTAIRLGSRGVAVLTAATD
>NZ_CP014859.1|WP_157421209.1|4904826_4905663_+|hypothetical-protein
MIPQHLPVDCDERVRVDLEGRWQRVRSRLRLALVVLPSVQLVIALVGLGLLTFGAGERGLGALVIGALCCLPVGLILVRIRRGLVIPKVSEWTSAGLLPTLVTAALAAIALLGSADLRDNRGLASVLLIAAILVPVPVFAAARGAVGLLLSAPLALAGRSGFALTTRLRVRRFRDAHVHLEADRVRWVVQVIRQHGARTVASGHLPLSELQSASTSTTENPVIDARLGRGVVARPGPVLVLRAAHRTVALTVGNASEFAELCQQRSDWLHGRQDRTPP
>NZ_CP014859.1|WP_157421208.1|4903614_4904745_+|hypothetical-protein
MGMELPESLQWVASIALGADWPESDEDKLREMRDAWETAGTDITAVKETAQAAAQSAAATMQGETAEQFQTYWEEFEGYLVAFSEMSQQLSTGCGDMALEVEHAKISIYIALAALAVQIIALLAAAAASLGTASAGIPVAQAATQVVVRQILQKLIQNILLNIATNLATDYGIQAFQMARGDRSGLDHGNFGNHIVNGVIQGAGQTVGGAVTSAIPTGASRGMGGAALRGAGAGAVGGFAQGVTEFTAQGGVSSLTGGEYGSGWDYRNLTSNTISGTIGGAQGNMSDRTQGLAESTFPNQTTEHSTPRNNPSHAREVLDSGRNWPVGGRAPEGFENPYNSGTREQVGINGSNVIDQAGRHRPQNQGDDSPLPEARE
>NZ_CP014859.1|WP_069851314.1|4903267_4903597_+|hypothetical-protein
MSDGYSADTTALRGVAPQFSSAADQLLDAHERLTASLSAAAGAWGNDEPGTNFGTAYEPAAEEGTAAFGTFAEGLNAIRDNLDASAEQWDSDDHAAEQAFQQQAQGLGY
>NZ_CP014859.1|WP_069851312.1|4902728_4903271_+|YbaB/EbfC-family-nucleoid-associated-protein
MIMSDSDDRRAELERRLPILKAHAAALTEQLERQTDQLAEAQESAKQAHGEATSPDGLVSVVVDGTGAITQLQLAPTVFARSTTERLAGSIVETIARAKAQSQAQVSDAFAEVTQPPVVDLPEVFDGAPSLQQLFETANRPLAPMDGPDRSTAGNPPPQRRDSRDEPDDDDGFMMRRGSW
>NZ_CP014859.1|WP_069851310.1|4901459_4902485_+|substrate-binding-domain-containing-protein
MNPTASIREVAAAARVSVGTVSNVLNRPAVVAPATRDRVLAAIESLGFVRNESARQLRSGTARTIGLVVLDVGNPFFTDVARGVEDVATEAGHVVILCNSDESSARESRYLDLLIEQRAHAVLITPVGDSLEPVRRLQQRGVSVVLLDHPTASEEVCSVSVDDVVGGDLATTHLLAGGHQNLVMVTGPESIRQCADRLAGARVAVERTGRPEDALRTVEVPALNVASGQRAAEQLLAAPTLPDGVFCANDLLALGLLQVLMRAGVRIPEDVALVGYDDIDFASAAAVPLTSVRQPRYLIGRTAADLVISETLVPKEHTHQHTVFTPELVVRDSSHPRRSRG
>NZ_CP014859.1|WP_069851328.1|4913339_4913729_+|winged-helix-turn-helix-transcriptional-regulator
MHAFDVLGDPVRRRILELLADGERTSGAVTEVIRTEFGISQSAVSQHLRVLRDNGFASVQAEGARRIYAIEPAPLSEIDAWLDQFRRIWTQRLDALETELARGKRARRLPADGPGPAGAGKPNPPTNGT
>NZ_CP014859.1|WP_084643308.1|4913744_4914377_+|SRPBCC-domain-containing-protein
MEELAAVRRTMGTGSVPAGEAYTVELRRRYDAPIGDVWDAITSPERLQRWLKPVTGDLRLGGDFELDGGEHGEVLRCEPPRLLKVSWLYGPEADDWPGTSEVEVRLAEGPDGDTEFELIHAAVIGEPSFPIYGPGAGGVGWDLALLSLARLLADGSTLDHDNFEKSPEGREFSRGSAAAWGQAHLAWGGEPEQVAAAVEATTKFYVPDQA
>NZ_CP014859.1|WP_069851332.1|4914643_4915132_+|SRPBCC-family-protein
MKYTVSIEIALPREQTAQLLADPAHLPKWLRGLVLHEPLSGVHGAVGTQSRVVFQSGKQQMEATETVTRREPVELSGIPKETVVHFDREIVGLGMWNAVRDRLTEVGPETTLWVSKNEYRFSGLLMRLVGLLMPGTFRKQSQQHMQDFKAFAEQGKDVRNEG
>NZ_CP014859.1|WP_069851334.1|4915516_4917334_-|hypothetical-protein
MTTGYAVLDTETTGFTPGWHRVVEIGVVLLDVDGAVEGEWCTLINPERDLGPQHVHGISAANVRSAPLFADIAGDLAELLAGRVLVGHNLSFDVDFLAFEYGRLGLDVPLAVMPGLCTMQLAERYLDIPARSLAACCAAVGVPLIEAHSAQHDAYATAGLLASYLQVVGSPVPWQDLLASASQWRWPELPMPTGRTAHRGAVVGPREHFLTRLPEHGARSVDPGALDAYLTLLDAALLDRHLSLSEEDGLIDNALSAGLGRTEVLGAHRRYLSVVACAAAQEGVLPAAVVADLVTIAALIGLSVVDVDRARCHAVRELSSAGTGALVASGALVEPGAVAEAGDLAESGTAGVAKTQGESARCAGVEFETVARDAAATVCESVVGADERYVATGLGTAAGAAAGTSHGLGSGALSAAWGSGTEASPSDERRAEPRSKSIAVLGKHSETPGASGEGSAAAAVIETAASGPAPATIRARRVSRRRAGHRSQPTAESTSGPTADAEHAAPSKPGPQTWGRFRLCTGDRVVFTGQTRSPRERWSLRAVSAGLVEGSHVTRKTRLVVAADPDSLSGKARRARNYGIPIVTEEAFTKLLEKMLDTERPNDSG
>NZ_CP014859.1|WP_172803850.1|4918452_4919091_-|hypothetical-protein
MDLQSRHDSGASVLASTGRIVSVFAGGLAVGVGTFFGQGSLPALLSQALANSGASWSVATFLLVAFLVAAGPWSSAIAGILAMVGMVLGYYGTATIVLGTSGGRWMIIWLLVALVAGPVFGLAGYWWRVRRPGFEIAGIALLGGVYLEEAGRILLSGPQDYPFQGPGWLALVIGVGIPLLLGRSWRNRGIALVAALPVALLIHFVLMVLLPG
>NZ_CP014859.1|WP_157421210.1|4919385_4920039_+|cyclic-nucleotide-binding-domain-containing-protein
MGSTMAVRARLREVGRPKSYVQGETLIHEGSVSTEVLLIESGTVKVMLNDPTGAALMIGFYGAGALIGELGVIQDEPRSATVIARDRVQAVSIGREAFRRLHQLDPAVVQWVNQTLYERLRQADRRQLAVATKTVRARVVHQLLDWAEEPGTTTSKGTEIRGISQQELAQYISASPKSVEEVLNVLREAGLVSTARLWFLIPDRIALARYLEKTSGV
>NZ_CP014859.1|WP_069851339.1|4920145_4921069_+|hypothetical-protein
MSTMPEQRALLGVDLIDSSEYPGEQRRDLPGILAALLTAGMAGTALVDVMSTEDQHTGDGRLLAFPATHLPAVVLLATRLDELAAQRNARFRPSVRLRLAVELGALPDTLGYYGPAIDRARLLNADLFKAILARCSGLRSDGSPHSGLILSDRVHRAVFGDGWLTGLNSHDFAAVHLEEKASPGRAWIRVPGFDAFSITEFARQAAAPSADRNDEAPGPTNAPSAPEPPSPRPPTTVSGGRNFTNQAAVHGHQISGDHNQFTSTTFNATASGNTAGRDTTVAKFAVRGDNNGVQADNIHGDINFGGR
>NZ_CP014859.1|WP_069851341.1|4921068_4923081_+|hypothetical-protein
MTEDRPQQAEELDQKEKVFFPERYSRFQVEGDSHGVQADTIHGNQTWNYTELFVEAKPWDRVLSRDEMADGTPFIEPGGYEDARRLLSRTGVMALRGEGSGREFAAKRLLAEYRPRVVVELDPHRTLTVEPRFEQGHAYLWELCAVNGHSALSEPGFRRLASAVRAKGGLLILIPDDAFYLPSELDSTQVRLSPPAAMDVFSAIVGHRDACRAEEIISLAKENEEDLLRPGTSPGRAVQVADALMAAGADPIRIRETLDSFRGHRNATVERWFSVERTPMEISMAIAVAFFENRAMDPVYDLARSLLEAINKAQQSIDGVPPATIPIFETSRSGLLRRIEARGDIIEHPRHPGLQDETVRFLSSERGAAILTYVWRHYDRVRPVLLDWMSAPNFPTEFRLACVNALCLVTKDVPAHRPLDRIRSLASHQRLSSRELAAQALRRLARNPQLTEMVETLVDDWVHNDTKVMVRTTAALMLSTSYGKENLPKSLQRLARLAQAPNPQLRNNVVRSLLVLLADEKSRSAVLTALSRWTDPAVNRAGQQQVAFATFLWALGFNPQDDRILLTGPPPDVDASRTAQQTESLTATLLTRLVHDPSVFGDEAISQISTLAGGHEIHEARLCRMMRLVLPDSRWWPRTKFRWAYVTRFPQRGLQMARILQAYGRADRRG
>NZ_CP014859.1|WP_069851343.1|4923339_4925127_+|hypothetical-protein
MTAVMVPSQEWSATADGTVDPPVGGSVSAEDVRPEVLGGSHRAAADSTARLLDKDGSGANAVTFDEIRETIARRLMNCRADETPSSWRTLLEIATRLAATAASTATGCDESTPCLLWSVGIAVTAGQSDIRRSGEQVERGATGAPTDLATIARQPLLDAASDIDQDALSRAVSIPAHQFPGTTLPISPRLGTSLSAGMELAVSVGDAGRPSAPGAGCHSSEPPLYEHFLRPQLGDHQDATLRWGNADEPADPTILGPAVLALRAAVDASVRRVSNALETFQRCSMEARIALESVDRRHERPNVESLPLPPWPDVDTDIDRWWYQAGLSPDARALPRIDDDLIDRARRLASRVLAAIDGWEHAEAEAASVGRPDGVDKADAANRAVSPLGSTTPRWLTRLNGDCDPALLRSTEAVELRSALADFDLLVALELMTLIRLTTGIDGQGPLAADVIARYLLSPSRLGGDPGLRATARELATFVLCPAFEAMVRNAEERLDRDRRWRDERRIALSPLAAAARNHGPDARLVRAWSEVSMRVDTVEAELAATIRARQRAGRSGLNVGAAGEQQSGRPRLLSTCRPPRREAMAGAHQGPPSR
>NZ_CP014859.1|WP_172803921.1|4925417_4927475_-|S9-family-peptidase
MNDSDTTGHPVCPYADLDAYAELPRLADLRLSPGGTRLVVGVAMLDATKTRHISTLWEVDPNGVEPARRLTRSEKGESAAGFTPDGDLLFASNRPAPGATEDADAAALWVQPASGDAQVIADPPGGVHGVLVAPTGTVLFGSGLLPSAVDLAEDAALRTRRKDTKVSAILHEEYPIRHWDHDIGPDRTRLFVAEIGTGPSDAQLTPRDLTGHVGRALGDGSDWDLAPDGKTVVSTWIVPEVTAAQRFTLVAIDVATGARRILADDPGHEYESPRISPDGTQVAAVVRRRSTPKDAGDTWLAVFPVAGGPQRDLTSEWDRRPNAPRWTPDGTALILAADDNGRAPLWRVDIATGKPTRLTEDDAAYSDIALSPDGAWLYALRSAIGAPPAPIRLAMIEGAIPEPLPGPAEALGRIAPPPGRLTEITATASDGTALRAWLALPGGAGPGAPAPLLLWIHGGPVMSMNAWSWRWNPWLAVAKGYAVVLPDPALSTGYGRDFIQRGWADWGNEPFTDLMTLADVAADRSDIDADRTAAMGASFGGYMANWVAGHTDRFAAIVTHASDWMLADANESGDVAHEFTREMTWEDGDRNSPHHAVDQITTPMLVIHGDKDYRVPIHEGIRLWRDLLVRSADDNGVTPHKFLYFPDENHWILAPQHTKLWYETVFAFLDHHVHGKPWRRPEILG

Crispr_ID: NZ_CP014859_16

• CRISPR_ID: NZ_CP014859_16
• CRISPR_location: 5411446-5411900
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NZ_CP014859_16

Consensus_repeat	Method
GAGCCATCCCCGCATGCGCGGGGCCGAT	CRISPRCasFinder
GAGCCATCCCCGCATGCGCGGGGCCGAT	CRT
GAGCCATCCCCGCATGCGCGGGGCCGATG	PILER-CR

spacers of NZ_CP014859_16

>16.1|5411474|33|NZ_CP014859|CRISPRCasFinder,CRT
CCACCGACACAGCTCTGATCCCACAACGGTGGG
>16.2|5411535|33|NZ_CP014859|CRISPRCasFinder,CRT
GGTAAGCGCTTCCGTGTAGTTGTCGACGTGCGC
>16.3|5411596|33|NZ_CP014859|CRISPRCasFinder,CRT
GCTTCGGCGTTGATAAAGCGTTGCCCGTGTTCG
>16.4|5411657|33|NZ_CP014859|CRISPRCasFinder,CRT
GTGTGTGTGGTCGGTCAGGCCGCGAGACGCAGC
>16.5|5411718|33|NZ_CP014859|CRISPRCasFinder,CRT
GTCCTCGGTTTGCAGATCGCTTCGCACGTCGCA
>16.6|5411779|33|NZ_CP014859|CRISPRCasFinder,CRT
GGACAGCGTCGGTAGTGGATCGTGCACGTCTGC
>16.7|5411840|33|NZ_CP014859|CRISPRCasFinder,CRT
CCTCCGTAGTAGCCCCGGCGAAGTCCTCCAGGG
>16.8|5411536|32|NZ_CP014859|PILER-CR
GTAAGCGCTTCCGTGTAGTTGTCGACGTGCGC
>16.9|5411597|32|NZ_CP014859|PILER-CR
CTTCGGCGTTGATAAAGCGTTGCCCGTGTTCG
>16.10|5411658|32|NZ_CP014859|PILER-CR
TGTGTGTGGTCGGTCAGGCCGCGAGACGCAGC

CRISPR arrays and Neighbor proteins around NZ_CP014859_16

CRISPR arrays

The CRISPR arrays of NZ_CP014859_16

>merge|NZ_CP014859|16|5411446-5411900|CRISPRCasFinder,CRT,PILER-CR
GTGCCATCCCCGCATGCGCGGGGCCGATCCACCGACACAGCTCTGATCCCACAACGGTGGGGAGCCTTCCCCGCATGCGCGGGGCCGATGGTAAGCGCTTCCGTGTAGTTGTCGACGTGCGCGAGCCATCCCCGCATGCGCGGGGCCGATGCTTCGGCGTTGATAAAGCGTTGCCCGTGTTCGGAGCCATCCCCGCATACGCGGGGCCGATGTGTGTGTGGTCGGTCAGGCCGCGAGACGCAGCGAGCCATCCCCGCATGCGCGGGGCCGATGTCCTCGGTTTGCAGATCGCTTCGCACGTCGCAGAGCCATCCCCGCATGCGCGGGGCCGATGGACAGCGTCGGTAGTGGATCGTGCACGTCTGCGAGCCATCCCCGCATGCGCGGGGCCGATCCTCCGTAGTAGCCCCGGCGAAGTCCTCCAGGGGAGCCATCCCCGCATGCGCGGGGCCGAT

>NZ_CP014859|16|16|5411446-5411900|CRISPRCasFinder
GTGCCATCCCCGCATGCGCGGGGCCGAT	CCACCGACACAGCTCTGATCCCACAACGGTGGG
GAGCCTTCCCCGCATGCGCGGGGCCGAT	GGTAAGCGCTTCCGTGTAGTTGTCGACGTGCGC
GAGCCATCCCCGCATGCGCGGGGCCGAT	GCTTCGGCGTTGATAAAGCGTTGCCCGTGTTCG
GAGCCATCCCCGCATACGCGGGGCCGAT	GTGTGTGTGGTCGGTCAGGCCGCGAGACGCAGC
GAGCCATCCCCGCATGCGCGGGGCCGAT	GTCCTCGGTTTGCAGATCGCTTCGCACGTCGCA
GAGCCATCCCCGCATGCGCGGGGCCGAT	GGACAGCGTCGGTAGTGGATCGTGCACGTCTGC
GAGCCATCCCCGCATGCGCGGGGCCGAT	CCTCCGTAGTAGCCCCGGCGAAGTCCTCCAGGG
GAGCCATCCCCGCATGCGCGGGGCCGAT

>NZ_CP014859|16|11|5411446-5411900|CRT
GTGCCATCCCCGCATGCGCGGGGCCGAT	CCACCGACACAGCTCTGATCCCACAACGGTGGG
GAGCCTTCCCCGCATGCGCGGGGCCGAT	GGTAAGCGCTTCCGTGTAGTTGTCGACGTGCGC
GAGCCATCCCCGCATGCGCGGGGCCGAT	GCTTCGGCGTTGATAAAGCGTTGCCCGTGTTCG
GAGCCATCCCCGCATACGCGGGGCCGAT	GTGTGTGTGGTCGGTCAGGCCGCGAGACGCAGC
GAGCCATCCCCGCATGCGCGGGGCCGAT	GTCCTCGGTTTGCAGATCGCTTCGCACGTCGCA
GAGCCATCCCCGCATGCGCGGGGCCGAT	GGACAGCGTCGGTAGTGGATCGTGCACGTCTGC
GAGCCATCCCCGCATGCGCGGGGCCGAT	CCTCCGTAGTAGCCCCGGCGAAGTCCTCCAGGG
GAGCCATCCCCGCATGCGCGGGGCCGAT

>NZ_CP014859|16|13|5411507-5411718|PILER-CR
GAGCCTTCCCCGCATGCGCGGGGCCGATG	GTAAGCGCTTCCGTGTAGTTGTCGACGTGCGC
GAGCCATCCCCGCATGCGCGGGGCCGATG	CTTCGGCGTTGATAAAGCGTTGCCCGTGTTCG
GAGCCATCCCCGCATACGCGGGGCCGATG	TGTGTGTGGTCGGTCAGGCCGCGAGACGCAGC
GAGCCATCCCCGCATGCGCGGGGCCGATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069851938.1|5407400_5407580_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069851954.1|5417081_5417441_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_084643368.1|5399503_5403367_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP014859.1|WP_157421262.1|5418265_5418520_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069851950.1|5414621_5415854_-|allantoate-amidohydrolase	unknown	unknown	gnl|CDD|236456
NZ_CP014859.1|WP_069851944.1|5410183_5411341_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP014859.1|WP_157421259.1|5396265_5396601_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069851934.1|5398578_5399460_+|ABC-transporter-permease-subunit	unknown	unknown	unknown
NZ_CP014859.1|WP_069851946.1|5412115_5413276_-|imidazolonepropionase	unknown	unknown	gnl|CDD|237604
NZ_CP014859.1|WP_157421260.1|5416039_5416696_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP014859.1|WP_069851964.1|5422200_5422995_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP014859.1|WP_084643369.1|5403491_5407304_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	unknown	unknown	gnl|CDD|237030
NZ_CP014859.1|WP_069851942.1|5409517_5410057_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP014859.1|WP_157421261.1|5417441_5418260_-|hypothetical-protein	unknown	unknown	gnl|CDD|375877
NZ_CP014859.1|WP_069851928.1|5394900_5396019_+|alanine-dehydrogenase	unknown	unknown	gnl|CDD|240630
NZ_CP014859.1|WP_069851960.1|5418806_5420480_-|urocanate-hydratase	unknown	unknown	gnl|CDD|235448
NZ_CP014859.1|WP_084643370.1|5408263_5409439_-|linear-amide-C-N-hydrolase	unknown	unknown	gnl|CDD|238910
NZ_CP014859.1|WP_069851932.1|5397412_5398579_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NZ_CP014859.1|WP_069851962.1|5420535_5422068_-|histidine-ammonia-lyase	unknown	unknown	gnl|CDD|236484
NZ_CP014859.1|WP_069851948.1|5413272_5414622_-|formimidoylglutamate-deiminase	unknown	unknown	gnl|CDD|236420

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_069851960.1|5418806_5420480_-|urocanate-hydratase	gnl|CDD|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
NZ_CP014859.1|WP_084643368.1|5399503_5403367_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.04703e-166
NZ_CP014859.1|WP_069851950.1|5414621_5415854_-|allantoate-amidohydrolase	gnl|CDD|236456	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed.	6.35861e-172
NZ_CP014859.1|WP_069851944.1|5410183_5411341_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.30102e-43
NZ_CP014859.1|WP_069851962.1|5420535_5422068_-|histidine-ammonia-lyase	gnl|CDD|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NZ_CP014859.1|WP_069851946.1|5412115_5413276_-|imidazolonepropionase	gnl|CDD|237604	PRK14085, PRK14085, imidazolonepropionase; Provisional.	0
NZ_CP014859.1|WP_157421260.1|5416039_5416696_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.00161982
NZ_CP014859.1|WP_069851964.1|5422200_5422995_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	8.01047e-57
NZ_CP014859.1|WP_084643369.1|5403491_5407304_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0
NZ_CP014859.1|WP_069851942.1|5409517_5410057_-|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	4.00011e-07
NZ_CP014859.1|WP_157421261.1|5417441_5418260_-|hypothetical-protein	gnl|CDD|375877	pfam18451, CdiA_C, Contact-dependent growth inhibition CdiA C-terminal domain. Contact-dependent growth inhibition (CDI) systems encode polymorphic toxin/immunity proteins that mediate competition between neighboring bacterial cells. CDI is mediated by the CdiB/CdiA family of two-partner secretion proteins. This domain represents the C-terminal of CdiA proteins (CdiA-CT), which contains the CDI toxin activity. The C-terminal nuclease domain forms a stable complex with its cognate immunity protein. It is also sufficient to inhibit growth when expressed in E. coli cells, consolidating the idea that they constitute the functional CDI toxin. The CdiA-CT C-terminal domains are structurally similar to type IIS restriction endonucleases suggesting that the toxins have metal-dependent DNase activity.	6.26838e-12
NZ_CP014859.1|WP_069851928.1|5394900_5396019_+|alanine-dehydrogenase	gnl|CDD|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP014859.1|WP_084643370.1|5408263_5409439_-|linear-amide-C-N-hydrolase	gnl|CDD|238910	cd01935, Ntn_CGH_like, Choloylglycine hydrolase (CGH)_like. This family of choloylglycine hydrolase-like proteins includes conjugated bile acid hydrolase (CBAH), penicillin V acylase (PVA), acid ceramidase (AC), and N-acylethanolamine-hydrolyzing acid amidase (NAAA) which cleave non-peptide carbon-nitrogen bonds in bile salt constituents. These enzymes have an N-terminal nucleophilic cysteine, as do other members of the Ntn hydrolase family to which they belong. This nucleophilic cysteine is exposed by post-translational prossessing of the precursor protein.	4.11238e-13
NZ_CP014859.1|WP_069851932.1|5397412_5398579_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.77489e-92
NZ_CP014859.1|WP_069851948.1|5413272_5414622_-|formimidoylglutamate-deiminase	gnl|CDD|236420	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated.	1.70829e-167

Protein sequences

>NZ_CP014859.1|WP_069851944.1|5410183_5411341_+|serine-hydrolase
MTAPTAVNRAGGNNVPDDVDARLARVLQGLVAQRGVHHANIAITSGDGEQRWSAAASRSDDQRLRPETPFFIASITKRFVITLVLQAYERGELDLAAPINDYLSTDVITGIHVLRGIDRTSEITVRHLATHTSGLPDHFEKRRDGPSRYESLAAGRDSAWTFEDTMRVTREQQRPYFEPQDLTAPRQKARYSDTGFQLLIRILETVTDRSFADLLTERILDPLGLRHTWHPRHHPADPATAAPTPLYAKQRRLTLTSLIESSNDLFSTTADLLTFQRALLGGALFQDARTSEVLTERRNRLRNIPILRYGMGTMFFQVSRLVSPTRRPLTLVGHSGATGTWLFHCPELDLHLVGTVDQAKGQAIPFQAMARLLSGWRRSDRGRFL
>NZ_CP014859.1|WP_069851942.1|5409517_5410057_-|PadR-family-transcriptional-regulator
MAHVILGLLLIAPQSYYDLIKGFESGVALFYSASSGSIKRALDALLAQERIEVASVEAGGRGRKVYRVTDAGSAEFRAWMTADLAKADLETAALSRLYFLGLLEPADRLPVLRRITARIETDLAVLSDLDKQLDALDLPAERRDLVTHQRATLDYGIASHRFMLDWFRDHIDRQEPPIR
>NZ_CP014859.1|WP_084643370.1|5408263_5409439_-|linear-amide-C-N-hydrolase
MDVLVYQSPDERLAVRHVRIRGRNEEIGESLACIARSRHRVAAQDLLLPDGVAEGRREWAVRHYPELVARGIGIARGFGLDPADPTVDALGIGYNIQLPMPPQMVGCSVLTAPTVDAGMVVQRNFDFGFLSLPDAVFGPGSHPEAPAMLSEPYLMEIHPTDGGMRTLFMCAFDLCNGVIDGMNEAGLVVSLMQLIDRSAATFSPPETAPGLNELEVLRFILDRCRTVEDAQRVFNEQKIYQSWMPCHYIIADANGIVMMAEPGDDNTMRTVVKRDGSMRSTNHSLLRPVPESWENDPEMRGSIERLQRMDAHVIGEPGQPFTTVRLAHIADQVAVNTRWPESGTVLGGTLWSASYRPRDRALAIRFWSGPETGGSGPNLSPEMQFQLDPTA
>NZ_CP014859.1|WP_069851938.1|5407400_5407580_+|hypothetical-protein
MYFTDRGLEELEERRGDESVTLSWLADRMRAFVDNNPEFEDAVERLATFLARDDSDDED
>NZ_CP014859.1|WP_084643369.1|5403491_5407304_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit
MSSSTPASQFGPNEWLVEEMYEQFLTNPSSVDPAWHDFFADYKPTHRSGRDGKESVGQQVGGTSSSTGTTTQTKADQQATSPQRNGQREQGATTAPAASAPKKSTSTTDSQKTSTVTSPTATPSAATPQPATSKPSPQKAATKTPVRHTDTADKPEGEQRKPLRGAAAAIAKNMEQSLTVPTATSVRAVPAKLLFDNRIVINNHLKRTRGGKVSFTHLIGYAIVRALESFPGMNRFYAETNGKPTMVTPEHVNLGLAIDLPGKDGSRSLVVASIKKCEGTSFLQFWQAYEDIIRKARTGKLTADDFSGTTISLTNPGTIGTNHSVPRLTAGQGTIVGVGAMEYPAEFQGSSEKALVKLGISKIMTLTSTYDHRVIQGAESGDFLRRVHQLLLGEDGFYDDIFTSLRLPYEPVRWVSDIPEGAVDKTARVLELIDAYRTRGHLMANTDPLNYRQRRHPDLDILSHGLTLWDLDREFPVGGFAGSERMKLRDVLGVLRDSYCRTLGVEYMHILEPDEREWLQKLVEVPHRHPDAAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGSETVIPLLDAVLDKASEHELDEVVIGMPHRGRLNVLANVVGKPIAQIFREFEGNLDPGQAHGSGDVKYHLGAEGKYFRMFGDGETTVSLTSNPSHLEAVNPVLEGIVRAKQDMIDKGENGFTVLPVLLHGDAAFAGQGVVAETLNLSLLRGYRTGGTLHVIINNQVGFTTAPEHSRSSQYSTDVAKMIGAPVFHVNGDDPEACVWAAKLAVEYRQAFGKDVVIDMVCYRRRGHNEGDDPSMTQPKMYSVIDTMRSVRKTYTESLIGRGDISVEDAEKALRDYASQLEYVFNEVRELEKHPPAPSPSVESEQLVPTKLDTAVPAETIIRIADAHTELPEGFTPHPRVKPVLERRAKMAREGSIDWAFAELLALGSLTMEGRLVRLSGQDSRRGTFVQRHAVVIDKKSGAEYTPLQNLGDDQARFMTYDSALSEFAALGFEYGYSVANPEALVLWEAQFGDFVNGAQPIIDEFISSGEAKWGQRSDVVLLLPHGHEGQGPDHTSGRIERFLQLCAEGSMTVSMPSTPANYFHLLRRHALDGVNRPLVVFTPKQLLRLKAAVSEVADFTPGSKFQSVLDDPTVKDPSAVTKVLLCSGKISYELNAERLKRGITDTAILRMEQLYPVPRRKLAAALERYPNAQDIRWVQEEPANQGAWPFLGLNLPDLLPERLSGLKRVSRRAMAAPSAGSNKVHEVEQKEILDTALS
>NZ_CP014859.1|WP_084643368.1|5399503_5403367_+|ABC-transporter-ATP-binding-protein
MPLRSPHHTEATAESEKSQQGWLHRLSAACWVHRRTVLLSFIASVVGVGLEALIPLLTREAVDGAVAGRTDGLWLILGVMAALGLLRFGTAFVRRYEAGRLALNVQHDLRQAVFASVTRFDGGKQDSVRTGQIASRAISDLQLVNSLLSMVPLATGSLVFAVVSLGVMLWLSPLLTVLALVVLPLVFIESLRTKRVLYPATWVAQQRASEVAQQVEETVTGVRVVKSFGQEHREVATLENTARKLFGDRLRAARLTSRPAATLAALPSLGQVGVLGVGGWLAMNGSISLGTFLAFTTYMVGLVGPARMLSSLLVSAQLARAGVERVYELIDSQPEVAEAEDAVELPEGPVAVELVDVRFGYTRDDPVLDGVSLRIEPGETLAVVGPAGSGKSTISLLLPRFYDVHGGAVRLGPPGAEQDVRELRTTSLRGAIGVVFEEAFLFSDTVRANLAYGRPDATDAEIRAAAVAAEAADFIERLPDGYDTRVGERGLSLSGGQRQRIALARALLTDPRVLLLDDATSAVDAVTEAAIHDTLQSVTQDRTTLLIAHRRSTLALADRIAVLDRGRVIDVGTEAELLDRCPLFRALLAHGDAIDSPGSSAPGENGAEPAVTAALWPEVADNGLAFDDRQRVSASAGMGNDRRGVSSGGAGMRAAGGSSSLFGGMVPTPELLAQVDRLPPALDRPRLHDEDPTAPDPNFRLRKLLRLVRWPLALAILLVSLDAIASVALPSLFRYGIDAGVSGGAATALQWATVGGVLIVVVSWLTVAWQTVVAAKAGETLLYLLRVRTFSHLQRLGLDYYEREQAGRIMTRMTTDVDALSHFLQTGLANAVVSLLTLFGIVGALLITDVPLALVALAPLPVLVIATMIFQRLSSAAYTQAREQVSLVNADLQENVSGVRVAQAFSREARSAANFAARSENYRRIRLRAQRYISIFFPFVALLSDVAQIAVLGVGAFALASGSTSPGVLLAFLLYLRLLFGPVQQLSTVFDNYQQAKVGLRRIRDLLRTPPSVPEPAVPLPVPSRLRGEVEFVEVGFSYPGAQRKALADVSLRVGAGERVALVGATGAGKSTLVKLLGRFYQTEEGVIRVDGVDIREHGVVDYRRHLGVVPQEPHLFSGTVADNIGYGRPDAGPAEIESAARAVGALPMIGGLPQGFRQQVGERGNNLSAGQRQLVSLARTELVEPDLLLLDEATAALDPATEAIVHAADDRLAASRTTFVVAHRLATAAKADRIFVFDQGRIVESGTHRELLAQGGRYAGLWAADRAADTPGPTATSGNGTTESIQ
>NZ_CP014859.1|WP_069851934.1|5398578_5399460_+|ABC-transporter-permease-subunit
MNRLIKSEFRKIFSTNLWWALLIPAGLFCFLLALLGGTVGNMFGTAVNTEIPESEMESIGSFTSLLTTLTFAAGLVAAGIFAGIFGALGMAGEARHKTITTTFLVSDSRSSVLGAKVVSYAAIGALYGLVSVILGSLGAGIGASFTSFPDIGSWLLLSLVAVVVMSLWTILGLGLGALISNQAGVVLTLVLLVLIGEGLIAQLFAEMGVENAADYLPGGSASAALLGLAVTLGLQPFLDSVGVTIDQLSAEAPEMSMFTDMSDQWLISALVFLLWTAIFVAAGWLANNKRDIT
>NZ_CP014859.1|WP_069851932.1|5397412_5398579_+|ATP-binding-cassette-domain-containing-protein
MHDGTGRIVVQGLTKQFGPVTAVQNLGFTVEPGTVTGFLGPNGSGKTTTLRMLLGLVHPTTGQATINGRRFDQLGNPARVVGAVLEAQSFHPTRSAYNHLRSFAAAIGAPDRVVNEVLGLVGLYEAGRRKPKGFSLGMRQRLALATALLGDPQVLVLDEPSNGLDPEGIAWLRGFLRDFASRGRTVLISSHLLREVEQTVDQVVIISRGQSMYHGSLDQLRAQRPSRVLVQTDEANKLVGALREAGHQNIESTPDGRLAIGAVTTKQVAEIAAKAGAPVYGIQEEHVDLESLFLEMTSGQYVGAPGFGQQQHQQQPPPGWGPPPGSGGFPAQNPYQQQGGPQQGGYPPQGPPQGGYPQVGYPQGGAPPSNPYNQPPGNQGQPGTGGNH
>NZ_CP014859.1|WP_157421259.1|5396265_5396601_+|hypothetical-protein
MDNSTERHASSPSIPTPATPQESTTTDEVATGIATASALEPADVRADDDRAWWVACHDPFGRDRSVTVLVDDGEVAVVPPPGAGAVLSARQTRRLRSTLDRAARTAGNRRP
>NZ_CP014859.1|WP_069851928.1|5394900_5396019_+|alanine-dehydrogenase
MRIAVPREIKNHEYRVALTPAGVNELTGRGHEVLVESGAGVGSGISDADYATAGAKIVDSPEAVWAEGDLVLKVKEPLPEEYPRLRSEQVLFTYLHLAGDRALTEAVLASGVTGIAYETVQTEDRTLPLLAPMSEVAGRLAPMVGINSLLRPAGGRGILPSGVPGVAPARVVVIGGGVAGLNAATIAVGLRADVELLDTNVARLREIDGIHGGTMRTITANSYTIEQAVVEADLVIGAVLVPGARAPKLIDNELVARMRPGSVLVDISIDQGGCFADSRPTSHDDPTFRVHDSLFYCVTNMPGAVPHTSTHALTNVTLPYVTKLADRGWRAACASDRSLAGGLNVHQGTLVNAAVGQAHSMDYVDVGEVVGD
>NZ_CP014859.1|WP_069851946.1|5412115_5413276_-|imidazolonepropionase
MTSTLITGIGELTTNDEELGRPADAALVLDGDRIAWIGAASAAPAADEILDVEGRAVLPGWVDSHTHLVFAGDRTAEFEARMAGAAYAAGGIAVTVEATRGATDAELAAGLRKHVDEAAAQGTTCVETKTGYGLTVADEVRAARIAAEVADEVTFLGAHLVPPGADAEDYLDEVCGPMLDAVAPYARWADVFCETGAFDETQSRRVLTAAAAKGLGLRVHGNQLGQGPGVRLAVELGAASVDHCTHLSDADIEALAGSATVATLLPACDLSTRQPLPPGRRLLDAGATVALASNCNPGSSYTSSMAFCVTTAVLQMGLSVEEAVRAATWGGARALRRETGDGAVGVLRPGARADVHVLDAPSATHLAYRPGVPLTHAVWRKGSRVR
>NZ_CP014859.1|WP_069851948.1|5413272_5414622_-|formimidoylglutamate-deiminase
MRYWAPYALVGGESPRVEWGVLLEVADGRFHTVRPGVAAPPDAVRLSGLAIPGLANAHSHAFHRALRGRTHVGGGTFWTWRKQMYALAERLNPDSYYRLARAVYGEMVLAGITSVGEFHYLHHEIGGIRYDDPNEMGLALVAAARDAGLRITLLDTCYLAGGFGKPLEGVQLRFGDVDADGWAVRAEALLAQLTDRPGVDPYRVRVGAAVHSVRGVPAEALGVVAGWSQRFRAPLHVHLSEQRAENEACQAAHGVTPTQLLADHGVLGELTTAVHATHLNVPDIGLLGASHTGVCLCPTTEQDLADGIGLGRNLLDAGSPLSLGTDGHSMIDIFAEAKAMEMHERLRTETRGHFSAEELWTAATSTGHASLGWGSTGVIESGARADLVTLDLDGVHLAGIEPTAAIFAATAADVRDVIIEGTSVVQNRVHGTLGDPGALLRDAIEELRR
>NZ_CP014859.1|WP_069851950.1|5414621_5415854_-|allantoate-amidohydrolase
MSGSQHATPPTPATATGLLAAIADVGADRRRGGFSRHGYDTAELDLRAWFVEQATRRDLDVRTDRNGNIWAWWGKPGPDAVITGSHLDSVPGGGAFDGPLGVVSSLAAVDELRAKGFTPTKPLAIVVFAEEEGGRFGIACLGSRLMAGTIDPAKAAALRDPDGVSLGEAMTAAGLDPSRLGRDDEALAQIGCFVELHVEQGRGLIDQAAPVGVASSILAHGRWRFTFTGEGNHAGATPIADRRDPMLPAAGLVLAARRIAAEVEGARATVGRLVPTPGGTNVIASSVDLWLDARAEDDARTKSVVERIREAAGEVAEAEGCAVRITEESYGDTVVFDSALRDDLAAALGGVPALPTGAGHDAGVLASQVPTAMLFVRNPTGVSHAPAEHAEPEDCEDGVQALTTVLEKLA
>NZ_CP014859.1|WP_157421260.1|5416039_5416696_-|hypothetical-protein
MTQHDHAFLAGRRSSTSFDHSATTPRAVPAAPGGARGDRPRAAAGLLSASPRPTPPRPAPPRPTPPRPSAPWPGAARSDREPTAPRTVDEALDVLARSRFTTSRAPGDAQVPFTLLYTYGWPCHVDAVHLRAEDDATAMRLRSGGASSPLFDEGDLVWRCEGTFLTVVGELLRLPMPGHRGAPERTVRVPSGLWIPGQAASPVAEAAPVADHRFACAL
>NZ_CP014859.1|WP_069851954.1|5417081_5417441_-|hypothetical-protein
MGDTYEIYFGSAGSGNPKERFAELVSAAIDAPLQPDDDPYRNYWAERDGVYFDLYSEHGMDNDAGIPFEQMPYSVTLRSDIAREEQLRIAEAVFERLREAGLRPIYLVWGIERTIRHAD
>NZ_CP014859.1|WP_157421261.1|5417441_5418260_-|hypothetical-protein
MTGFDRVATSLRHVKSETESAAAELSGIDRELGELLTRLDGVARGSTAAEMADVPKLIEQARVEIDNARTRYRNTAGRIHAYLAEHGHSPTSGTTALVGAREPTPRSAESARHNETIPLPNITPPHQPAGTVTDDPATWPGRIREPTGDEAFSPEEQSVAERLARLDEVEIVIQPPGSHRTPDAVIDGVGVEFKTLTDPNPDAERVKNTLNRSVRKGGQGTEIIIDGRRTTLTEADAIRGTFRFLRAPGNARKLARIRIWGADFDFEWKRGS
>NZ_CP014859.1|WP_157421262.1|5418265_5418520_-|hypothetical-protein
MGGAGEVRAEILDIAGMLPIQRLIRQQENSSAIVAELVESWRGSEYPDAPQAVADLRHVGADLTAAIGALGRGAELLRDYSARL
>NZ_CP014859.1|WP_069851960.1|5418806_5420480_-|urocanate-hydratase
MGVLFVTTGPRTVRAARGTTLTAKSWSTEAPLRMLHNNLDPEVAERPDDLVVYGGTGKAARNWASFDAITAELTNLAEDETLLVQSGKPVGVLRTHEWAPRVLIANSNLVGDWTSWPEFRKLEHLGLTMYGQMTAGSWIYIGTQGILQGTYETFAAVAAKRFGGSLAGTLTLTAGLGGMGGAQPLAVTMNDGVALVVEVDPERARRRVETRYLDEIAEDIDDAVAKALAAKQERRARSIGLIGNAAEVFPELLRRGVAIDIVTDQTSAHDPLSYLPKGVELADWTDYAERKPDEFTDRARESMVEHVAAMVGFKDAGAEVFDYGNSIRGEAQLGGYERAFEFPGFVPAYIRPLFAEGRGPFRWAALSGDPADIRRTDEAILELFPDNKPLARWIRMAQERVEFQGLPARICWLGYGERHLAGLRFNELVASGEISAPLVLGRDHLDSGSVASPYRETEGMADGSDAIADWPLLNALINTASGATWVSIHQGGGVGMGRSIHAGQVTLADGTELAAQKIERVLTNDPGMGVLRHVDAGYDRAEEVAAERGLHVPLSSR
>NZ_CP014859.1|WP_069851962.1|5420535_5422068_-|histidine-ammonia-lyase
MSQPIAVGVEPLTRDQVVAVARTGAGVRITEEARTAVTTARAHIEALAEAPTPTYGVSTGFGALATRHIPQESRADLQRSLVRSHAAGAGEPVEPEVVRAMMVLRLSTLTAGHSGVRPETVAALAALIGSGLTPVVHEHGSLGCSGDLAPLSAVALTLMGEGEVLDAAGTRIPTAEAFAAHGLRPIVLAEKEGLALTNGTDGMLGMLVLAAADLADLLDIADLTAAMSVEALLATDRVFAPELQALRPHPGQARSAARLTALLAGSEIVASHRGADCNRVQDAYSLRCAPQVHGAARDTLTHAELVADRELASVIDNPVVLADGRVESNGNFHGAPVGYVLDFLAVPVADVASMAERRTDRLLDVHRSHGLPPFLAADPGVDSGYMIAQYTQAAVVSELKRLASPASVDSIPSSAMQEDHVSMGWSAARKLRRGLDGLRTVLAVELLTAARAIDLRAPLRPAPATAAALALLRTRVPGPGPDRHLAPDIAEARHLVTSGELLDVVAAQLA
>NZ_CP014859.1|WP_069851964.1|5422200_5422995_+|IclR-family-transcriptional-regulator
MGDSSDVPALRRGLAVLGLLARRATPTSAAVISRELELPRSTTYHLLGELVRTGYVSHLPEERRYGLGMAAFELGSAYLRHDPLERLARPLLARLAQRVEHNAQLGVLHGAQAVYLSKEQPARPQTLVTDVGVRLPAELTASGRAMLAHLPAPQVRALFPGSSSFVQRTGRGPRDLPSLRRLLASERRRGWAVEDGYITESWASVASAVFDHGGRPVASVSVTFRHVCDRESDCGQIWPETAAEVRRTAADLTVRLGGTAPESD

Crispr_ID: NZ_CP014859_17

• CRISPR_ID: NZ_CP014859_17
• CRISPR_location: 5551056-5551449
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP014859_17

Consensus_repeat	Method
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	PILER-CR
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CRISPRCasFinder
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CRT

spacers of NZ_CP014859_17

>17.1|5551084|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CGCCCACGCGCCCTTCTTCGTGGGGTCGACCTG
>17.2|5551145|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
GTTGCTTGCGCCCAAGTCCATGGGACCTAATCC
>17.3|5551206|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CCGGGCAGGGGGCCGCCGGTGCCCCGGCACGGG
>17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
CTCGCCGTCGACCATCACCCTGCGAGATCCACT
>17.5|5551328|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
GTCCTTCCAGGTCATATAGGTGACTCGGTGCGC
>17.6|5551389|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT
GTTCCCCGCTTCGATCTGGTCGACCTTGGACGA

CRISPR arrays and Neighbor proteins around NZ_CP014859_17

CRISPR arrays

The CRISPR arrays of NZ_CP014859_17

>merge|NZ_CP014859|17|5551056-5551449|PILER-CR,CRISPRCasFinder,CRT
GTCCGCTCCGCGCAGGCGGAGGTGAGCCCGCCCACGCGCCCTTCTTCGTGGGGTCGACCTGGTCCGCTCCGCGCAGGCGGAGGTGAGCCGTTGCTTGCGCCCAAGTCCATGGGACCTAATCCGTCCGCTCCGCGCAGGCGGAGGTGAGCCCCGGGCAGGGGGCCGCCGGTGCCCCGGCACGGGGTCCGCTCCGCGCAGGCGGAGGTGAGCCCTCGCCGTCGACCATCACCCTGCGAGATCCACTGTCCGCTCCGCGCAGGCGGAGGTGAGCCGTCCTTCCAGGTCATATAGGTGACTCGGTGCGCGTCCGCTCCGCGCAGGCGGAGGTGAGCCGTTCCCCGCTTCGATCTGGTCGACCTTGGACGAGTCCGCTCCGCGCAGGCGGAGGTGAGCC

>NZ_CP014859|17|14|5551056-5551449|PILER-CR
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CGCCCACGCGCCCTTCTTCGTGGGGTCGACCTG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTTGCTTGCGCCCAAGTCCATGGGACCTAATCC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CCGGGCAGGGGGCCGCCGGTGCCCCGGCACGGG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CTCGCCGTCGACCATCACCCTGCGAGATCCACT
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTCCTTCCAGGTCATATAGGTGACTCGGTGCGC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTTCCCCGCTTCGATCTGGTCGACCTTGGACGA
GTCCGCTCCGCGCAGGCGGAGGTGAGCC

>NZ_CP014859|17|17|5551056-5551449|CRISPRCasFinder
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CGCCCACGCGCCCTTCTTCGTGGGGTCGACCTG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTTGCTTGCGCCCAAGTCCATGGGACCTAATCC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CCGGGCAGGGGGCCGCCGGTGCCCCGGCACGGG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CTCGCCGTCGACCATCACCCTGCGAGATCCACT
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTCCTTCCAGGTCATATAGGTGACTCGGTGCGC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTTCCCCGCTTCGATCTGGTCGACCTTGGACGA
GTCCGCTCCGCGCAGGCGGAGGTGAGCC

>NZ_CP014859|17|12|5551056-5551449|CRT
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CGCCCACGCGCCCTTCTTCGTGGGGTCGACCTG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTTGCTTGCGCCCAAGTCCATGGGACCTAATCC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CCGGGCAGGGGGCCGCCGGTGCCCCGGCACGGG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CTCGCCGTCGACCATCACCCTGCGAGATCCACT
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTCCTTCCAGGTCATATAGGTGACTCGGTGCGC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GTTCCCCGCTTCGATCTGGTCGACCTTGGACGA
GTCCGCTCCGCGCAGGCGGAGGTGAGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_084643828.1|5547579_5548086_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP014859.1|WP_069852141.1|5542924_5544565_+|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP014859.1|WP_069852163.1|5557188_5557923_+|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NZ_CP014859.1|WP_084643830.1|5553865_5554042_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_157421274.1|5546661_5547402_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_157421276.1|5558139_5558289_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852161.1|5556440_5557070_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_157421275.1|5555636_5556110_+|hypothetical-protein	unknown	unknown	gnl|CDD|173748
NZ_CP014859.1|WP_069854070.1|5552444_5553239_+|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|235546
NZ_CP014859.1|WP_069852145.1|5544953_5545976_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852149.1|5548844_5550815_+|Xaa-Pro-dipeptidyl-peptidase	unknown	unknown	gnl|CDD|235435
NZ_CP014859.1|WP_084643384.1|5554105_5554330_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069852139.1|5542518_5542875_+|DUF86-domain-containing-protein	unknown	unknown	gnl|CDD|225236
NZ_CP014859.1|WP_069852151.1|5551514_5552357_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375319
NZ_CP014859.1|WP_157421273.1|5546313_5546661_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069854067.1|5542246_5542522_+|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|224583
NZ_CP014859.1|WP_069852153.1|5554326_5555181_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
NZ_CP014859.1|WP_069852159.1|5556109_5556349_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852137.1|5541201_5542062_-|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl|CDD|223417
NZ_CP014859.1|WP_069852143.1|5544623_5544869_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	unknown	unknown	gnl|CDD|379386

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_084643828.1|5547579_5548086_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.28277e-39
NZ_CP014859.1|WP_069852141.1|5542924_5544565_+|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP014859.1|WP_069852163.1|5557188_5557923_+|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	2.46683e-43
NZ_CP014859.1|WP_084643830.1|5553865_5554042_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.57618e-14
NZ_CP014859.1|WP_157421275.1|5555636_5556110_+|hypothetical-protein	gnl|CDD|173748	cd07853, STKc_NLK, Catalytic domain of the Serine/Threonine Kinase, Nemo-Like Kinase. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. NLK is an atypical mitogen-activated protein kinase (MAPK) that is not regulated by a MAPK kinase. It functions downstream of the MAPK kinase kinase Tak1, which also plays a role in activating the JNK and p38 MAPKs. The Tak1/NLK pathways are regulated by Wnts, a family of secreted proteins that is critical in the control of asymmetric division and cell polarity. NLK can phosphorylate transcription factors from the TCF/LEF family, inhibiting their ability to activate the transcription of target genes. In prostate cancer cells, NLK is involved in regulating androgen receptor-mediated transcription and its expression is altered during cancer progression. MAPKs are important mediators of cellular responses to extracellular signals. The NLK subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	0.00774559
NZ_CP014859.1|WP_069854070.1|5552444_5553239_+|glucose-1-dehydrogenase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.52885e-68
NZ_CP014859.1|WP_069852149.1|5548844_5550815_+|Xaa-Pro-dipeptidyl-peptidase	gnl|CDD|235435	PRK05371, PRK05371, x-prolyl-dipeptidyl aminopeptidase; Provisional.	0
NZ_CP014859.1|WP_084643384.1|5554105_5554330_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.28311e-13
NZ_CP014859.1|WP_069852139.1|5542518_5542875_+|DUF86-domain-containing-protein	gnl|CDD|225236	COG2361, COG2361, Uncharacterized conserved protein [Function unknown].	7.82684e-27
NZ_CP014859.1|WP_069852151.1|5551514_5552357_-|helix-turn-helix-domain-containing-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	2.04566e-47
NZ_CP014859.1|WP_069854067.1|5542246_5542522_+|nucleotidyltransferase-domain-containing-protein	gnl|CDD|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	1.23415e-18
NZ_CP014859.1|WP_069852153.1|5554326_5555181_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	7.15371e-10
NZ_CP014859.1|WP_069852137.1|5541201_5542062_-|biotin--[acetyl-CoA-carboxylase]-ligase	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	5.49612e-69
NZ_CP014859.1|WP_069852143.1|5544623_5544869_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	6.28793e-10

Protein sequences

>NZ_CP014859.1|WP_069852149.1|5548844_5550815_+|Xaa-Pro-dipeptidyl-peptidase
MPTKEPTRRLLALPLAGVLLAGTALPAVASEEPTSADAAFSLENGVSAPIHSYADAIRETVWVDIGLDGDRDGVSDRVAADIIRPSEPAAAGEQVPVIMDASPYYSCCGRGNESQLKTYDEAGRPEGFPLFYDNYFVPRGYATVLVDLAGTNRSEGCVDVGGPSDVTSATAVVEWLNGAATGYTSPTGDDQASAEWSTGAVGMIGKSYDGTIANGVAATGTPGLKTIVPIGAISSWYDYYGSDGAAFRNSPSGLARTVEQGGRADCGHAKAALDAGAPTNGDWTELWEERDHTKDAANVQASVLAVHGLGDLNVKMIHFGRWWEALAEHDVPRKVWLTQAGHVDPFDFRREEWVDTLHRWFDRWLLEVPNGIDTEPAATIERAPDVWADEPVWPPASTRNVELNPRPSSTDGLGHLGRHSQPPDETQSIERGAGGNQFAWAESPDQPADDRLLFYTPPLRHDARIAGTGEVTVSVSSSLPVGHLTATLVDYGPNTTRDYLGSGEGIRTLTSRSCWGESTSFDSACYRDTETTTAEVDLEIFARGWADIANHSSPTEGEPLEPGQSYDVTFRLSTTDHVVPEGHQLALIIGGSDSRYLRNPGGTPALTVGLRGTSVDVPLVDGQIHFERAREEPPTVREHRVPDEPTILMNGDQVRR
>NZ_CP014859.1|WP_084643828.1|5547579_5548086_-|M23-family-metallopeptidase
MAPLYNDVAPTLQFHTLAGEAQAHSARVAEQAAAEAEANRPEFVKPAEGTFTSGYGARWGTNHFGIDIAGPIGTPVVSATDGTVINAGPATGFGQWVRVQAPDGTITTYGHVETFTASVGEQVKAGDQIATIGNRGQSTGPHLHFEVNVGGQKLDPQPWLAERGITVQ
>NZ_CP014859.1|WP_157421274.1|5546661_5547402_-|hypothetical-protein
MSVTIVVEQLRQAHALLTEARAATARAGHEIAEGSEIFDEGTRGSIWPQVEQIRRFGRAASDEVRLAYTELGQAQDIIDDYCMSIAGHRIGGHAGIEGGADSTAIGPGTAPDDSQSRYPEWIAERERAGAVINPANVDRMSQLPDGRTVWVERENVKGGAEHILDDDRAGQFARAGVPAEQIMNLLFAALERGKVVGYSGRDRPVYEVIFEGERRRLAITVTLDGLIVGAHPISLKRKLRTRVWRD
>NZ_CP014859.1|WP_157421273.1|5546313_5546661_-|hypothetical-protein
MTRSVVVSLLVGWQEDPFYYDFDDPEEYGHSIEEAGEQLQLPPELVRELVIWDSEYQATYRPSDYRNSGFASVAEEESWRERGKALAQRIKQESPVVASVDYRAEGLHPKGWCVF
>NZ_CP014859.1|WP_069852145.1|5544953_5545976_-|hypothetical-protein
MKPTYADFAFRPPILGNAVVHTSEASAAGSHLAVGAGGSVTLDFTLSKGEEIAEATLKVRALVAKSNRRTPGSAPVDVLVNGELVTERLAIPGGGDLPQDNVLAVPGALLVPGENTLEIRTAADARNQLWLYRITLDSVYERDHSERALGAAHAANSVFAFDTKRCASGHSSWVAAPPLLFHVERGENSVLEHLSWRGTDGAEAAIVFTAEMTGFYGHHRAADGTQSEFRGEVTGRWAFPDGIADARVHRFATEEGWGGGWHRSPDELRFVLDDGGAPVERIAWRDQRCNSGSITVRTGLNPDTGGRPYDFLGIYQRANEGAIGYRGVAVPELDKTLHRD
>NZ_CP014859.1|WP_069852143.1|5544623_5544869_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit
MTDQQPSDQQPSAGRPVLRVVRGEPDDAELAALAAVFAASSAGEPAEAAAPERSGWADRAALLRRPLSPGAGAWRWSAFRG
>NZ_CP014859.1|WP_069852141.1|5542924_5544565_+|acyl-CoA-carboxylase-subunit-beta
MSSATEPVGELSDTQPDIHTTAGKLADLARRNHEAVHAGSARAVEKQHAKGKHTARERIDMLLDPGSFLELDEHARHRSINFGQERNRPYGDGVVIGFGTVDGRPICVFSQDVTVFGGSLGEVYGEKIVKVLDLALKTGRPIVGINEGGGARIQEGVVSLGLYGEIFRRNTHASGVIPQISLIMGATAGGHVYSPALTDFVVMVDKTSHMFITGPDVIKTVTGEEVTFEELGGAETHNTRSGVAHYLGNDEEDAISYVKSLLSHLPSNNLSEPPLYPVAVADQGAVVDSLTETDLELDTLIPDSANQPYDMHEVLTRVLDDGEFLEVHERFAPNILVGFGRIEGQSVGVVANQPTQYAGCLDIDASEKAARFVRTCDAFNVPVLTFVDVPGFLPGTEQEWNGIIRRGAKLLYAYAEATVPLITTITRKAYGGAYDVMGSKHLGADVNLAWPTAQIAVMGAQGAANIVHRKTLAQAAANGEDTDALRAKLQQEYEDTLCNPYVAAERGYVDSVIAPSHTRGYLARSLRLLRDKRETLPPKKHGNIPL
>NZ_CP014859.1|WP_069852139.1|5542518_5542875_+|DUF86-domain-containing-protein
MKRSAKQRLDDIIGAATEIIENCPKTRDQLSEDRILQLGLVKLTEIIGEAANHVGDELQLAHPEVPWRAVIGMRHRTVHSYFEIDFSVLWKVISEEIPVLLPQIVSIRATLDQDPSSM
>NZ_CP014859.1|WP_069854067.1|5542246_5542522_+|nucleotidyltransferase-domain-containing-protein
MEEVLAHRDEIHAIARRHGVSNVRVFGSVARGEADEDSDLDLLIDIDGGYIAMTSFALGVEDLLNVFTQVATPNGLKRQMRDRILAEAVPV
>NZ_CP014859.1|WP_069852137.1|5541201_5542062_-|biotin--[acetyl-CoA-carboxylase]-ligase
MAETSQRAPLDQRFLRSALVRPAGPYAAVDVRASTGSTNADLVARAVEGAPDRTVLLAEEQTAARGRQRRSWTSPAGAGLYLSVLLRPEVPPAQLGWLPLLAGLALVRAVRAVSGVEAAMKWPNDLLVGPHQRKCAGILAEAVHLGQAADAGQPGQAIVLGIGLNVDHRLDELPPRPHGPEATSLHLEGAISLDRTELAIRLLEELDGTERTWRSHDGDVARSGQLAAYQDASATLGRRIRVELAGDRAVLGTAVDVDAGGRIVVDTDAGPTESFSAGDVVHLRAG
>NZ_CP014859.1|WP_069852151.1|5551514_5552357_-|helix-turn-helix-domain-containing-protein
MDRQELAAFLRSRRERITAADVGLPAGTRRRTPGLRREEVAQLAFISTEYYTRMEQANAPRPSGEVLAGVARALRLSDSERDHLHRLAGAPLGPRTGPTREVRQSIRDLLDRLPNAAGIVLSATYEVLAWNALAAALMEDFSALAPRDRNLIRWVFLRPDAGAYGLSDVQEFALAATRRLRATSARYPDDPQIHELVAELLAGSAEFARLWESHDVCTAPALKKTFHHPLVGAITVDCDGFDITDTDQQVVLYTAAPGSSSDEALRLLSVIGTQRMDVPG
>NZ_CP014859.1|WP_069854070.1|5552444_5553239_+|glucose-1-dehydrogenase
MTTTSNIDITPSAGLLADKVAFVSGAGRGIGAAAARLFAKEGAAVLLAARTESQLAAVTEEIRAAGGRADYVVCDLSEADSVRHAVGQTVEHFGRLDLAFNNGAIGLPPGPLDQMAEADFDHVYTVNLRGVWLAMSAQVAAIRATAGSGAIVNVSSIGSHGSNSVFPAYGAMKRAVNSLTESAAVTYGPEGIRVNAVAPGTTLTEMIKGWEENTPGIVDQLNAQTPLGRAAQPDEVAEAAAWLLSNRASYVTGAVLRVDGGARV
>NZ_CP014859.1|WP_084643830.1|5553865_5554042_-|DUF397-domain-containing-protein
MTWRKAARSGSTSNCVEIGRGSELVGIRDTKNRAGGTLMVNPASFGAFLNAVKTDRMS
>NZ_CP014859.1|WP_084643384.1|5554105_5554330_-|DUF397-domain-containing-protein
MTRLVEHAGWRKSRRSQNTSNCVEIRHAAEQVGIRDTKNRAGGVLIVDCAAFGFFLNAIKSNSLGDRSSAELAD
>NZ_CP014859.1|WP_069852153.1|5554326_5555181_-|helix-turn-helix-transcriptional-regulator
MTVTPTPKAVALGAALRRAREDVGLSARALSLKMHLTASTVSRWESGARSPRPVDVAAVLAVLGVPEEEREELVEMARSTANRQWIAAGLPEQRRALTALLEAERDAAEIVCLSPLLIPGLMQTSAYARAIMSGGGVPQDEVETRVRVRIGRREVYARRDRPVKVLAILGEGALRRMVGGRTVLVSQLRVLIDEASLPTVDLRIIPHSAGWSPDLEGSFDLLTFPDTRDPIVHIENRRSALFFHELDDVEAYRESLDTVMSVAMSPEASIEFIADVIKDLETTP
>NZ_CP014859.1|WP_157421275.1|5555636_5556110_+|hypothetical-protein
MRSFRDPAQWSEWVPAVLLGTPSRSMWVAVSCNRAQGHILVEGHHPARRPSLAALTTGATTEVINALRYRRRRDITVPAIGNGLEDRELLVADPGDESALVTIRNTQSILGRWSVHTHRLPELCWALKHAHGLVSGTESAAAIVPTDLAATIAGGAP
>NZ_CP014859.1|WP_069852159.1|5556109_5556349_+|hypothetical-protein
MPDRPWFVRSVRACDTHRAASEHWTRDDRINVRPDCDPSTTFTALNRTPIALPYYDEQRCPACLTIARPARQRLSAVVR
>NZ_CP014859.1|WP_069852161.1|5556440_5557070_+|hypothetical-protein
MSGPAEEPMLIEQDVCPMVGLILDRHLVFVDTGQPVPTSGDRVTALCGTPVTIGPRPAEVLPGIPATHAADCPDCRVVLEGRPPEIDTVDEVIRLFLRRTSATPVHIVEIEATTTPSPMLIARCGEVFDGTADQVTAGDGMPCTLCLLLSLSRMRKRESAPRWTRFDNSCRVRHSHCRSRSVLPNELRYAAMTTGTALRHTRIGDPVLH
>NZ_CP014859.1|WP_069852163.1|5557188_5557923_+|dienelactone-hydrolase-family-protein
MPSKMLHIPTEDGQADAFAAFPDKGGQHPGVLMYADAFGIRPALREMARELAEHGYYVLVPNFFYRQGPTPVIDLPEHIGEDVRPALVDRFMPLIEAHTAEHVLSDADAYLKFLTSQPEVSAGPVAVTGYCIGGLLAMRTAVAHPGQVAALASFHGPVGADGPDSLHRLTCAVHFGHAETDLTTEDLGELNRALDAAGVDYTSEIYPGTIHGFTMSDTDAYNPAALQHHWDRLLPLLDRTLAGS
>NZ_CP014859.1|WP_157421276.1|5558139_5558289_+|hypothetical-protein
MNTNPDNRPSESVESEEVRQARRAALDELTRVAAGNGSADDTNHFIPTR

Crispr_ID: NZ_CP014859_18

• CRISPR_ID: NZ_CP014859_18
• CRISPR_location: 5553452-5553785
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NZ_CP014859_18

Consensus_repeat	Method
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	PILER-CR
GTCCGCTCCGCGCAGGCGGAGGTGAGCCG	CRISPRCasFinder
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	CRT

spacers of NZ_CP014859_18

>18.1|5553480|33|NZ_CP014859|PILER-CR,CRT
ATGGGGCTAGTGCGGTTTCGTGGGGTCGGTCCG
>18.2|5553541|33|NZ_CP014859|PILER-CR,CRT
GCTCGCGATTCCTTTCCGGATGTACCCCGGATC
>18.3|5553602|33|NZ_CP014859|PILER-CR,CRT
GTCCCTGGCGCGTTGTGCGCGGGATTTCGTGGC
>18.4|5553663|33|NZ_CP014859|PILER-CR,CRT
ACCGCAGTTGATGCACTCGTCGGCGGATTCGTC
>18.5|5553481|32|NZ_CP014859|CRISPRCasFinder
TGGGGCTAGTGCGGTTTCGTGGGGTCGGTCCG
>18.6|5553542|32|NZ_CP014859|CRISPRCasFinder
CTCGCGATTCCTTTCCGGATGTACCCCGGATC
>18.7|5553603|32|NZ_CP014859|CRISPRCasFinder
TCCCTGGCGCGTTGTGCGCGGGATTTCGTGGC
>18.8|5553664|32|NZ_CP014859|CRISPRCasFinder
CCGCAGTTGATGCACTCGTCGGCGGATTCGTC
>18.9|5553725|32|NZ_CP014859|CRISPRCasFinder
CGTCCGCTGAGTCCGACGTCTGACACGCCGTG
>18.10|5553724|33|NZ_CP014859|CRT
GCGTCCGCTGAGTCCGACGTCTGACACGCCGTG

CRISPR arrays and Neighbor proteins around NZ_CP014859_18

CRISPR arrays

The CRISPR arrays of NZ_CP014859_18

>merge|NZ_CP014859|18|5553452-5553785|PILER-CR,CRISPRCasFinder,CRT
GTCCGCTCCGCGCAGGCGGAGGTGAGCCATGGGGCTAGTGCGGTTTCGTGGGGTCGGTCCGGTCCGCTCCGCGCAGGCGGAGGTGAGCCGCTCGCGATTCCTTTCCGGATGTACCCCGGATCGTCCGCCCCGCGCAGGCGGAGGTGAGCCGTCCCTGGCGCGTTGTGCGCGGGATTTCGTGGCGTCCGCTCCGCGCAGGCGGAGGTGAGCCACCGCAGTTGATGCACTCGTCGGCGGATTCGTCGTCCGCTCCGCGCAGGCGGAGGTGAGCCGCGTCCGCTGAGTCCGACGTCTGACACGCCGTGGTCCGCTCCGCGCAGGCGGAGGTGTGGCG

>NZ_CP014859|18|15|5553452-5553723|PILER-CR
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	ATGGGGCTAGTGCGGTTTCGTGGGGTCGGTCCG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GCTCGCGATTCCTTTCCGGATGTACCCCGGATC
GTCCGCCCCGCGCAGGCGGAGGTGAGCC	GTCCCTGGCGCGTTGTGCGCGGGATTTCGTGGC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	ACCGCAGTTGATGCACTCGTCGGCGGATTCGTC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC

>NZ_CP014859|18|18|5553452-5553785|CRISPRCasFinder
GTCCGCTCCGCGCAGGCGGAGGTGAGCCA	TGGGGCTAGTGCGGTTTCGTGGGGTCGGTCCG
GTCCGCTCCGCGCAGGCGGAGGTGAGCCG	CTCGCGATTCCTTTCCGGATGTACCCCGGATC
GTCCGCCCCGCGCAGGCGGAGGTGAGCCG	TCCCTGGCGCGTTGTGCGCGGGATTTCGTGGC
GTCCGCTCCGCGCAGGCGGAGGTGAGCCA	CCGCAGTTGATGCACTCGTCGGCGGATTCGTC
GTCCGCTCCGCGCAGGCGGAGGTGAGCCG	CGTCCGCTGAGTCCGACGTCTGACACGCCGTG
GTCCGCTCCGCGCAGGCGGAGGTGTGGCG

>NZ_CP014859|18|13|5553452-5553784|CRT
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	ATGGGGCTAGTGCGGTTTCGTGGGGTCGGTCCG
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GCTCGCGATTCCTTTCCGGATGTACCCCGGATC
GTCCGCCCCGCGCAGGCGGAGGTGAGCC	GTCCCTGGCGCGTTGTGCGCGGGATTTCGTGGC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	ACCGCAGTTGATGCACTCGTCGGCGGATTCGTC
GTCCGCTCCGCGCAGGCGGAGGTGAGCC	GCGTCCGCTGAGTCCGACGTCTGACACGCCGTG
GTCCGCTCCGCGCAGGCGGAGGTGTGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_069852164.1|5558373_5559483_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224753
NZ_CP014859.1|WP_084643828.1|5547579_5548086_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP014859.1|WP_069852141.1|5542924_5544565_+|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP014859.1|WP_069852163.1|5557188_5557923_+|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NZ_CP014859.1|WP_084643830.1|5553865_5554042_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069854072.1|5559479_5561153_-|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|224099
NZ_CP014859.1|WP_157421274.1|5546661_5547402_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852161.1|5556440_5557070_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_157421275.1|5555636_5556110_+|hypothetical-protein	unknown	unknown	gnl|CDD|173748
NZ_CP014859.1|WP_069854070.1|5552444_5553239_+|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|235546
NZ_CP014859.1|WP_069852145.1|5544953_5545976_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_084643384.1|5554105_5554330_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_069852139.1|5542518_5542875_+|DUF86-domain-containing-protein	unknown	unknown	gnl|CDD|225236
NZ_CP014859.1|WP_069852151.1|5551514_5552357_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375319
NZ_CP014859.1|WP_157421273.1|5546313_5546661_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_157421276.1|5558139_5558289_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852153.1|5554326_5555181_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
NZ_CP014859.1|WP_069852159.1|5556109_5556349_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852149.1|5548844_5550815_+|Xaa-Pro-dipeptidyl-peptidase	unknown	unknown	gnl|CDD|235435
NZ_CP014859.1|WP_069852143.1|5544623_5544869_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	unknown	unknown	gnl|CDD|379386

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_084643828.1|5547579_5548086_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.28277e-39
NZ_CP014859.1|WP_069852141.1|5542924_5544565_+|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP014859.1|WP_069852163.1|5557188_5557923_+|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	2.46683e-43
NZ_CP014859.1|WP_084643830.1|5553865_5554042_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.57618e-14
NZ_CP014859.1|WP_069854072.1|5559479_5561153_-|iron-ABC-transporter-permease	gnl|CDD|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	1.82058e-80
NZ_CP014859.1|WP_069852164.1|5558373_5559483_-|ABC-transporter-substrate-binding-protein	gnl|CDD|224753	COG1840, AfuA, ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism].	1.3963e-34
NZ_CP014859.1|WP_069852151.1|5551514_5552357_-|helix-turn-helix-domain-containing-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	2.04566e-47
NZ_CP014859.1|WP_069854070.1|5552444_5553239_+|glucose-1-dehydrogenase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.52885e-68
NZ_CP014859.1|WP_084643384.1|5554105_5554330_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.28311e-13
NZ_CP014859.1|WP_069852139.1|5542518_5542875_+|DUF86-domain-containing-protein	gnl|CDD|225236	COG2361, COG2361, Uncharacterized conserved protein [Function unknown].	7.82684e-27
NZ_CP014859.1|WP_157421275.1|5555636_5556110_+|hypothetical-protein	gnl|CDD|173748	cd07853, STKc_NLK, Catalytic domain of the Serine/Threonine Kinase, Nemo-Like Kinase. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. NLK is an atypical mitogen-activated protein kinase (MAPK) that is not regulated by a MAPK kinase. It functions downstream of the MAPK kinase kinase Tak1, which also plays a role in activating the JNK and p38 MAPKs. The Tak1/NLK pathways are regulated by Wnts, a family of secreted proteins that is critical in the control of asymmetric division and cell polarity. NLK can phosphorylate transcription factors from the TCF/LEF family, inhibiting their ability to activate the transcription of target genes. In prostate cancer cells, NLK is involved in regulating androgen receptor-mediated transcription and its expression is altered during cancer progression. MAPKs are important mediators of cellular responses to extracellular signals. The NLK subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	0.00774559
NZ_CP014859.1|WP_069852153.1|5554326_5555181_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	7.15371e-10
NZ_CP014859.1|WP_069852149.1|5548844_5550815_+|Xaa-Pro-dipeptidyl-peptidase	gnl|CDD|235435	PRK05371, PRK05371, x-prolyl-dipeptidyl aminopeptidase; Provisional.	0
NZ_CP014859.1|WP_069852143.1|5544623_5544869_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	6.28793e-10

Protein sequences

>NZ_CP014859.1|WP_069854070.1|5552444_5553239_+|glucose-1-dehydrogenase
MTTTSNIDITPSAGLLADKVAFVSGAGRGIGAAAARLFAKEGAAVLLAARTESQLAAVTEEIRAAGGRADYVVCDLSEADSVRHAVGQTVEHFGRLDLAFNNGAIGLPPGPLDQMAEADFDHVYTVNLRGVWLAMSAQVAAIRATAGSGAIVNVSSIGSHGSNSVFPAYGAMKRAVNSLTESAAVTYGPEGIRVNAVAPGTTLTEMIKGWEENTPGIVDQLNAQTPLGRAAQPDEVAEAAAWLLSNRASYVTGAVLRVDGGARV
>NZ_CP014859.1|WP_069852151.1|5551514_5552357_-|helix-turn-helix-domain-containing-protein
MDRQELAAFLRSRRERITAADVGLPAGTRRRTPGLRREEVAQLAFISTEYYTRMEQANAPRPSGEVLAGVARALRLSDSERDHLHRLAGAPLGPRTGPTREVRQSIRDLLDRLPNAAGIVLSATYEVLAWNALAAALMEDFSALAPRDRNLIRWVFLRPDAGAYGLSDVQEFALAATRRLRATSARYPDDPQIHELVAELLAGSAEFARLWESHDVCTAPALKKTFHHPLVGAITVDCDGFDITDTDQQVVLYTAAPGSSSDEALRLLSVIGTQRMDVPG
>NZ_CP014859.1|WP_069852149.1|5548844_5550815_+|Xaa-Pro-dipeptidyl-peptidase
MPTKEPTRRLLALPLAGVLLAGTALPAVASEEPTSADAAFSLENGVSAPIHSYADAIRETVWVDIGLDGDRDGVSDRVAADIIRPSEPAAAGEQVPVIMDASPYYSCCGRGNESQLKTYDEAGRPEGFPLFYDNYFVPRGYATVLVDLAGTNRSEGCVDVGGPSDVTSATAVVEWLNGAATGYTSPTGDDQASAEWSTGAVGMIGKSYDGTIANGVAATGTPGLKTIVPIGAISSWYDYYGSDGAAFRNSPSGLARTVEQGGRADCGHAKAALDAGAPTNGDWTELWEERDHTKDAANVQASVLAVHGLGDLNVKMIHFGRWWEALAEHDVPRKVWLTQAGHVDPFDFRREEWVDTLHRWFDRWLLEVPNGIDTEPAATIERAPDVWADEPVWPPASTRNVELNPRPSSTDGLGHLGRHSQPPDETQSIERGAGGNQFAWAESPDQPADDRLLFYTPPLRHDARIAGTGEVTVSVSSSLPVGHLTATLVDYGPNTTRDYLGSGEGIRTLTSRSCWGESTSFDSACYRDTETTTAEVDLEIFARGWADIANHSSPTEGEPLEPGQSYDVTFRLSTTDHVVPEGHQLALIIGGSDSRYLRNPGGTPALTVGLRGTSVDVPLVDGQIHFERAREEPPTVREHRVPDEPTILMNGDQVRR
>NZ_CP014859.1|WP_084643828.1|5547579_5548086_-|M23-family-metallopeptidase
MAPLYNDVAPTLQFHTLAGEAQAHSARVAEQAAAEAEANRPEFVKPAEGTFTSGYGARWGTNHFGIDIAGPIGTPVVSATDGTVINAGPATGFGQWVRVQAPDGTITTYGHVETFTASVGEQVKAGDQIATIGNRGQSTGPHLHFEVNVGGQKLDPQPWLAERGITVQ
>NZ_CP014859.1|WP_157421274.1|5546661_5547402_-|hypothetical-protein
MSVTIVVEQLRQAHALLTEARAATARAGHEIAEGSEIFDEGTRGSIWPQVEQIRRFGRAASDEVRLAYTELGQAQDIIDDYCMSIAGHRIGGHAGIEGGADSTAIGPGTAPDDSQSRYPEWIAERERAGAVINPANVDRMSQLPDGRTVWVERENVKGGAEHILDDDRAGQFARAGVPAEQIMNLLFAALERGKVVGYSGRDRPVYEVIFEGERRRLAITVTLDGLIVGAHPISLKRKLRTRVWRD
>NZ_CP014859.1|WP_157421273.1|5546313_5546661_-|hypothetical-protein
MTRSVVVSLLVGWQEDPFYYDFDDPEEYGHSIEEAGEQLQLPPELVRELVIWDSEYQATYRPSDYRNSGFASVAEEESWRERGKALAQRIKQESPVVASVDYRAEGLHPKGWCVF
>NZ_CP014859.1|WP_069852145.1|5544953_5545976_-|hypothetical-protein
MKPTYADFAFRPPILGNAVVHTSEASAAGSHLAVGAGGSVTLDFTLSKGEEIAEATLKVRALVAKSNRRTPGSAPVDVLVNGELVTERLAIPGGGDLPQDNVLAVPGALLVPGENTLEIRTAADARNQLWLYRITLDSVYERDHSERALGAAHAANSVFAFDTKRCASGHSSWVAAPPLLFHVERGENSVLEHLSWRGTDGAEAAIVFTAEMTGFYGHHRAADGTQSEFRGEVTGRWAFPDGIADARVHRFATEEGWGGGWHRSPDELRFVLDDGGAPVERIAWRDQRCNSGSITVRTGLNPDTGGRPYDFLGIYQRANEGAIGYRGVAVPELDKTLHRD
>NZ_CP014859.1|WP_069852143.1|5544623_5544869_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit
MTDQQPSDQQPSAGRPVLRVVRGEPDDAELAALAAVFAASSAGEPAEAAAPERSGWADRAALLRRPLSPGAGAWRWSAFRG
>NZ_CP014859.1|WP_069852141.1|5542924_5544565_+|acyl-CoA-carboxylase-subunit-beta
MSSATEPVGELSDTQPDIHTTAGKLADLARRNHEAVHAGSARAVEKQHAKGKHTARERIDMLLDPGSFLELDEHARHRSINFGQERNRPYGDGVVIGFGTVDGRPICVFSQDVTVFGGSLGEVYGEKIVKVLDLALKTGRPIVGINEGGGARIQEGVVSLGLYGEIFRRNTHASGVIPQISLIMGATAGGHVYSPALTDFVVMVDKTSHMFITGPDVIKTVTGEEVTFEELGGAETHNTRSGVAHYLGNDEEDAISYVKSLLSHLPSNNLSEPPLYPVAVADQGAVVDSLTETDLELDTLIPDSANQPYDMHEVLTRVLDDGEFLEVHERFAPNILVGFGRIEGQSVGVVANQPTQYAGCLDIDASEKAARFVRTCDAFNVPVLTFVDVPGFLPGTEQEWNGIIRRGAKLLYAYAEATVPLITTITRKAYGGAYDVMGSKHLGADVNLAWPTAQIAVMGAQGAANIVHRKTLAQAAANGEDTDALRAKLQQEYEDTLCNPYVAAERGYVDSVIAPSHTRGYLARSLRLLRDKRETLPPKKHGNIPL
>NZ_CP014859.1|WP_069852139.1|5542518_5542875_+|DUF86-domain-containing-protein
MKRSAKQRLDDIIGAATEIIENCPKTRDQLSEDRILQLGLVKLTEIIGEAANHVGDELQLAHPEVPWRAVIGMRHRTVHSYFEIDFSVLWKVISEEIPVLLPQIVSIRATLDQDPSSM
>NZ_CP014859.1|WP_084643830.1|5553865_5554042_-|DUF397-domain-containing-protein
MTWRKAARSGSTSNCVEIGRGSELVGIRDTKNRAGGTLMVNPASFGAFLNAVKTDRMS
>NZ_CP014859.1|WP_084643384.1|5554105_5554330_-|DUF397-domain-containing-protein
MTRLVEHAGWRKSRRSQNTSNCVEIRHAAEQVGIRDTKNRAGGVLIVDCAAFGFFLNAIKSNSLGDRSSAELAD
>NZ_CP014859.1|WP_069852153.1|5554326_5555181_-|helix-turn-helix-transcriptional-regulator
MTVTPTPKAVALGAALRRAREDVGLSARALSLKMHLTASTVSRWESGARSPRPVDVAAVLAVLGVPEEEREELVEMARSTANRQWIAAGLPEQRRALTALLEAERDAAEIVCLSPLLIPGLMQTSAYARAIMSGGGVPQDEVETRVRVRIGRREVYARRDRPVKVLAILGEGALRRMVGGRTVLVSQLRVLIDEASLPTVDLRIIPHSAGWSPDLEGSFDLLTFPDTRDPIVHIENRRSALFFHELDDVEAYRESLDTVMSVAMSPEASIEFIADVIKDLETTP
>NZ_CP014859.1|WP_157421275.1|5555636_5556110_+|hypothetical-protein
MRSFRDPAQWSEWVPAVLLGTPSRSMWVAVSCNRAQGHILVEGHHPARRPSLAALTTGATTEVINALRYRRRRDITVPAIGNGLEDRELLVADPGDESALVTIRNTQSILGRWSVHTHRLPELCWALKHAHGLVSGTESAAAIVPTDLAATIAGGAP
>NZ_CP014859.1|WP_069852159.1|5556109_5556349_+|hypothetical-protein
MPDRPWFVRSVRACDTHRAASEHWTRDDRINVRPDCDPSTTFTALNRTPIALPYYDEQRCPACLTIARPARQRLSAVVR
>NZ_CP014859.1|WP_069852161.1|5556440_5557070_+|hypothetical-protein
MSGPAEEPMLIEQDVCPMVGLILDRHLVFVDTGQPVPTSGDRVTALCGTPVTIGPRPAEVLPGIPATHAADCPDCRVVLEGRPPEIDTVDEVIRLFLRRTSATPVHIVEIEATTTPSPMLIARCGEVFDGTADQVTAGDGMPCTLCLLLSLSRMRKRESAPRWTRFDNSCRVRHSHCRSRSVLPNELRYAAMTTGTALRHTRIGDPVLH
>NZ_CP014859.1|WP_069852163.1|5557188_5557923_+|dienelactone-hydrolase-family-protein
MPSKMLHIPTEDGQADAFAAFPDKGGQHPGVLMYADAFGIRPALREMARELAEHGYYVLVPNFFYRQGPTPVIDLPEHIGEDVRPALVDRFMPLIEAHTAEHVLSDADAYLKFLTSQPEVSAGPVAVTGYCIGGLLAMRTAVAHPGQVAALASFHGPVGADGPDSLHRLTCAVHFGHAETDLTTEDLGELNRALDAAGVDYTSEIYPGTIHGFTMSDTDAYNPAALQHHWDRLLPLLDRTLAGS
>NZ_CP014859.1|WP_157421276.1|5558139_5558289_+|hypothetical-protein
MNTNPDNRPSESVESEEVRQARRAALDELTRVAAGNGSADDTNHFIPTR
>NZ_CP014859.1|WP_069852164.1|5558373_5559483_-|ABC-transporter-substrate-binding-protein
MRKIRILASLAVAGSLVAAGCAPPQFTPVVDSSAEVDTSDGLVINGERIADAEELAAAKEEGRISLYSGYVENSEKEVIKVFEEDTGIKVDLVRLVPNRLSERVLSEQGAGRLGADVVRTSDFDIASRMREAGVFQSYEVADYDNMDETVRYFDGDFYRVFNPLYTFAYNTALVDEEDAPKSWHDLNDEQWKDDLGITQVGAGGSSLTLNRFQEQNLGEDFLPTLADQNPRIFDSSSAALESLARGEIPVATAVVSSVNIAASKNAPVNFVIPEEGMAAYDYFVGMTDAAVNTDAAELFLEWNLSKRGQDVFRQIGEFPARGDVEPPEILSQQLPTADSGKIVRIDPEVLIAAAEGDQQRWNGLFGYLG
>NZ_CP014859.1|WP_069854072.1|5559479_5561153_-|iron-ABC-transporter-permease
MPTGVLLIVLGVLVVVPMLFIALAAFSDNVPRPGSVVDSLSFDNFAILGSGEALGALGNSVLIAALASVFAMAIGCGLAFLAARADVPGKRFLYFVGIAPMFLPSLVGALAWSLLGSPATGFLNLVFQGIGLDITLNVYSMPGLIMVLALYYAPYAFLLVHGALSLMNPDLEEAAFVHGGTRRRTLSWVTFPLAMPAILGSGVLIFALTMENFPVAQVIGNPGQIETLPSFIYRLMNASPSRGTEAAAVAIALTAVLLVVTALQQRAVMRRKFTTVTGKGVKAKLVSLGRWKWPMFGLAMLYFLLAVVLPVGALLIAALQNSPYVSSIGQLAEPGALSFWNLGQLVISSDFLQSAGNSAVTAILAAVIGTGISFVVAYTVYRTNAPGRRILEFVAMAPLAVPAIVLGLGLLWTWLVVPLPIYGTVFVLVIAFMAVFLPQGYRGVTSSILQVDRDLEDSAVLLGARRAKAVSWVTLPLMRVGMVSTVLLLLMLCMRELSAALFLFTSDTRLLSILIFDNYDNGAMQGAASISLLYCVVILIIAVLAKSLGAKTVDGAR

Crispr_ID: NZ_CP014859_19

• CRISPR_ID: NZ_CP014859_19
• CRISPR_location: 5776152-5776298
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014859_19

Consensus_repeat	Method
GTATCCGCCCCGCGCACGCGGGGGTGTTCCC	PILER-CR

spacers of NZ_CP014859_19

>19.1|5776183|33|NZ_CP014859|PILER-CR
CATGTCGGATGCGGCGGACTCGATCGCCAGCCT
>19.2|5776247|30|NZ_CP014859|PILER-CR
GTTCTTCGCCGATGTGCAGGAGTGGGAGTC

CRISPR arrays and Neighbor proteins around NZ_CP014859_19

CRISPR arrays

The CRISPR arrays of NZ_CP014859_19

>merge|NZ_CP014859|19|5776152-5776298|PILER-CR
ACACCCGCGTGCGCGGGGAGGACATGTCGGATGCGGCGGACTCGATCGCCAGCCTGGGAACACCCCCGCGTGCGCGGGGCGGATGCGTTCTTCGCCGATGTGCAGGAGTGGGAGTCGGGAACACCCCCGCGTGCGCGGGGCGGATAC

>NZ_CP014859|19|16|5776152-5776298|PILER-CR
ACACCCGCGTGCGCGGGGAGGACATGTCGGA	TGCGGCGGACTCGATCGCCAGCCTGGGAACACC
CCCGCGTGCGCGGGGCGGATGCGTTCTTCGC	CGATGTGCAGGAGTGGGAGTCGGGAACACC
CCCGCGTGCGCGGGGCGGATAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014859.1|WP_084643423.1|5785470_5786487_-|EamA-family-transporter	unknown	unknown	gnl|CDD|273359
NZ_CP014859.1|WP_069852433.1|5767239_5767548_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_084643420.1|5777131_5778466_-|ATP-binding-protein	unknown	unknown	gnl|CDD|226951
NZ_CP014859.1|WP_069852439.1|5770609_5772292_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP014859.1|WP_069852456.1|5783264_5784677_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143465
NZ_CP014859.1|WP_069852435.1|5768415_5769438_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852429.1|5766369_5766681_+|chorismate-mutase	unknown	unknown	gnl|CDD|236117
NZ_CP014859.1|WP_069852440.1|5772321_5773215_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_CP014859.1|WP_069852444.1|5774466_5775309_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP014859.1|WP_069852454.1|5781502_5783071_-|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl|CDD|234614
NZ_CP014859.1|WP_069852458.1|5784798_5785440_-|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|225462
NZ_CP014859.1|WP_069852442.1|5773343_5774291_+|EamA-family-transporter	unknown	unknown	gnl|CDD|273359
NZ_CP014859.1|WP_084643421.1|5778690_5780088_+|PspC-domain-containing-protein	unknown	unknown	gnl|CDD|377200
NZ_CP014859.1|WP_069854108.1|5780363_5781389_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP014859.1|WP_069852437.1|5769665_5770424_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_157421290.1|5786558_5787056_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP014859.1|WP_069852452.1|5780071_5780302_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014859.1|WP_069852448.1|5776428_5777112_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014859.1|WP_084643418.1|5774294_5774483_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014859.1|WP_157421460.1|5767714_5768419_+|PIG-L-family-deacetylase	unknown	unknown	gnl|CDD|225031

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014859.1|WP_084643423.1|5785470_5786487_-|EamA-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	8.46843e-44
NZ_CP014859.1|WP_084643420.1|5777131_5778466_-|ATP-binding-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	4.31452e-24
NZ_CP014859.1|WP_069852439.1|5770609_5772292_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.6097e-100
NZ_CP014859.1|WP_069852456.1|5783264_5784677_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143465	cd07147, ALDH_F21_RNP123, Aldehyde dehydrogenase family 21A1-like. Aldehyde dehydrogenase ALDH21A1 (gene name RNP123) was first described in the moss Tortula ruralis and is believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and ALDH21A1 expression represents a unique stress tolerance mechanism. So far, of plants, only the bryophyte sequence has been observed, but similar protein sequences from bacteria and archaea are also present in this CD.	1.35921e-119
NZ_CP014859.1|WP_069852440.1|5772321_5773215_-|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.02655e-47
NZ_CP014859.1|WP_069852429.1|5766369_5766681_+|chorismate-mutase	gnl|CDD|236117	PRK07857, PRK07857, chorismate mutase.	1.53682e-28
NZ_CP014859.1|WP_069854108.1|5780363_5781389_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	6.8506e-90
NZ_CP014859.1|WP_069852444.1|5774466_5775309_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.77579e-10
NZ_CP014859.1|WP_069852454.1|5781502_5783071_-|glutamine-hydrolyzing-GMP-synthase	gnl|CDD|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP014859.1|WP_069852458.1|5784798_5785440_-|NAD(P)H-binding-protein	gnl|CDD|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	1.90699e-61
NZ_CP014859.1|WP_069852442.1|5773343_5774291_+|EamA-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	6.78682e-18
NZ_CP014859.1|WP_084643421.1|5778690_5780088_+|PspC-domain-containing-protein	gnl|CDD|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	8.1996e-18
NZ_CP014859.1|WP_157421290.1|5786558_5787056_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.1486e-19
NZ_CP014859.1|WP_069852448.1|5776428_5777112_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.10601e-64
NZ_CP014859.1|WP_084643418.1|5774294_5774483_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.24927e-12
NZ_CP014859.1|WP_157421460.1|5767714_5768419_+|PIG-L-family-deacetylase	gnl|CDD|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	1.5995e-37

Protein sequences

>NZ_CP014859.1|WP_069852444.1|5774466_5775309_-|helix-turn-helix-transcriptional-regulator
MTWMARSRILGDELRRHRNSCGLTLAELGARTGRGKSTIARWETGEKPIDRDDLLKILGALGITGPTESALLSLVGDLSQKSWYDEADMPKRLRDLAALESKATKITELAIAVVPGLIQTSAYAAAVLRGMGGPEDRILHRVENRIARQTVLAGSVQYTALLDELVLQRPVGGAEVMRAQLDQLATLSQQGNVTLRVLPVGLTHPGLTGAFILLEFAHGLPIVHIEQQRTSALLDRKAETAAYQATTSTLRAMAMDAEASRALIHQYADRWRDRAHGEHF
>NZ_CP014859.1|WP_084643418.1|5774294_5774483_-|DUF397-domain-containing-protein
MANTSETWKKSSKSTNESCIEVRHGSAAFGIRDSKDRTGGLLIVKRSAFEALLTAVKSGRLG
>NZ_CP014859.1|WP_069852442.1|5773343_5774291_+|EamA-family-transporter
MIRNTGSLVRMAVLASLFGSSFLLMKIALGSFSPAQITLIRLVLGAGVLLAICAARRIVLPREPRLWLIMTGAALLANTLPFTLFAVAEQTVDVGLSGVLNATTPLWALALAVALRRQRAVTGWNVVGVALGFIGVVLLLAPWQQADIHLFGAALCLAAAASYAVGYLYVERFLSGRGLKPVAMACMQLIAGSGLAVVAIPFMGRQPIDLALAPVVAIVVLGALGTGAAFVINHRLIADEGGAAASTVGYLLPLVSVLIGVLLLDERLALFQWAGMAVTLLGVALTRHRKSSAEATAPKPSERREQIVESEAAAG
>NZ_CP014859.1|WP_069852440.1|5772321_5773215_-|LysR-family-transcriptional-regulator
MLDVRRLQVLRAVVTGGSVSAAATELGFTPSAISQQLATLEREAGLPLLEKSGRGVRPTLVGSMLADRAKGILDGLADIEHELSDLRAGSTGLIRIRYFATAGVGLVPPAVAAFRQQNPDVRLELWLDDADPLADLRAGRADIALAVRNSSTVEEDSLRYLPLLDDPYRLVLPKGHRLASRRTIDMAELAQEQWVDPDRLHGPCREPVTVACAAAGFQPDYTVHTEDYATAQGLIAARLGIAIMPMIGLRTVHPGVVVRRLRKPEPTRSIMVVVRAAVAEQVVMQRMVAALKDAASA
>NZ_CP014859.1|WP_069852439.1|5770609_5772292_+|serine/threonine-protein-kinase
MSDEGRLVAARYRLDRRIGSGAMGVVWQGTDDRLGRVVAIKQLLLQPGLSPAETEEARQRAMREGRIAARLQHQNAIAVYDVADDNGQPCLIQEYLPSDSLATALTERGPLPPTEVARIGASVAGALAAAHAAGIVHRDIKPANILLGHNGEVKITDFGISRATGDVTVTKTGMLAGTPAYLAPEVAKGYDPGFGADVFSLGATLYAAVEGEPPFGTHENTLALLHLVAAGRINPPRQAGPLTALLMRLLRAEPIERPTMAQAREGMQAVAAGRPAPGPPMPVGTPRPTTNHAQPPATPANGPNATRLDARPVTDRPEPPRAAAAAPQAAARQPTNPPPRSTPPQASRTASPEPEEGFRGRAVLLTAVAVIAAALIGVLIAGVFFNGNDSRGSERPPSSSGSSSEAEAPPTDDPPAEDETSTDEGTPNRQIPREEVSLEDPPPSDEDEDEDGDEDEEDQEQSRPARSEALVSQYFGLLPGNYQQAYNLLGSEYQGSFDSYEGWWRDSVESVTITGGPNFDGGRVNVTLQFVRKDGAEVSENWGIEIVNEGGELRIGEVHN
>NZ_CP014859.1|WP_069852437.1|5769665_5770424_+|hypothetical-protein
MVRRQPRTTRTRRRAGAPWESAPSTAELPDGSTPDSIEDDTVLFRSVGTRAFALGGGLLVLTMSILATGIITSAPGVSDPDDAPQAAALVGPMAMRPDILTEYLAEPQVTPRLDEAAEVGPSGLRAVAEESDRVPPAEQQVISEPLLPVDTDRELVEQFYNVLAEDPQRASRLLGDELRSNGDAGFISAWENVRSFEVVTIREPQAGTVEATVAIDEAHGGRLYLTQQLVVGETPKRITEVKVLTVQQSATS
>NZ_CP014859.1|WP_069852435.1|5768415_5769438_+|hypothetical-protein
MNTASSDDDIAGPGGRGIGADRQAADRWADSRAVRPDNAAVEGVSAEAVPGAVRPDQDPRRSPLPEPDPLIDSDAVGLRKFDLGMVPASVTPPRSWRNAAWFTVTTSMTSLAVLLVTTALFLRPEERRAPDSLPLFPSGTPLPTLQGTQRSVPTVGAPHLLAAEDSESATHPGSESSTDGREYAHTHRFTDPTGTDREPTSSVGPAPSTTHHPGDGRPATASPVPSVTVGEGTPIVDGAEIRDQTAAFFEALGNDVGSAYELVTGELAEAGLPVFSQRYDDVASIDLRHVTINPVEGITVSTVIVTHHDGSQSTEYRELRFAGTTEPLITDDRLIPRNEW
>NZ_CP014859.1|WP_157421460.1|5767714_5768419_+|PIG-L-family-deacetylase
MVVTAHPDDVDFAASATIAGWTACGVQVTYCICTSGDAGGGFDDTPRSEIAALRESEQRAAAGAVGVEDVRFLGYSDGRVVDSLELRRDISRVIRAVRPERVLTHSPEFNWERIAIGHPDHRAVGAATVAAVYPDARNPFAHPELAEEGLDAWTVRELWLSGGPAERTNHVVDVTATIDKKFAALAAHRSQTAHVPELMEQLRAAMAESGAALLPQGDSSTTRLAETFQVVDTA
>NZ_CP014859.1|WP_069852433.1|5767239_5767548_+|hypothetical-protein
MEFLINLIAIIVTLAGLAAAVGNGGYLAMLNSAAKQRAGGGPVADYVKGRFPQAAGIGGAALLALLLTNGGIPLDIVAIIVGAGSGVAATNALNSTRRRYQS
>NZ_CP014859.1|WP_069852429.1|5766369_5766681_+|chorismate-mutase
MNVASSDSAPSGPGEPAPEEIRALRTEIDYLDSEILRLVRRRIEVSQQVGKARMAAGGPRIVTNREMAVLARYRELGPDGRELAMALLKLGRGRLGGAGDRAE
>NZ_CP014859.1|WP_069852448.1|5776428_5777112_-|response-regulator-transcription-factor
MNHPEAKTGQTQPVRVFLVDDHALFRTGAKAELTNASGIIEVVGEAGSVGEAVAGIGHFEPDVVLLDVHMPDGGGAEVLRRARKTHPNVVFLALSVSDAAEDVIAVIRAGARGYVTKTISARELVDAVVRVHHGDAVFSPRLAGFVLDAFADRPGAAPINDPELDLLTPRERDVLRLLARGYAYKEIAAELFISVKTVETHVSSVLRKTQLSNRYELSRWATDRRLI
>NZ_CP014859.1|WP_084643420.1|5777131_5778466_-|ATP-binding-protein
MSAAAGSQRTAQARRDPRTSAEATTGRTLRRRRSSRVIAGVAGGLADHLRVDVRWVRVIITLLAAVDGLGVVVYGALWAVVRQRSVDVAEPDSPRERTQAIGMVVLGFGLLVATSSFGQGLSGQLFFPASVALIGAVLVWREADETQRRRWAQGARTGVAEVFIGNGGRGAIIRSLSGAALVITGIVVLLVDSLALAPLQFALLSVIVTLIGTAVLTLPWWLRLVRDLDEERFARIRTEERAEIAAHLHDSVLQTLALIQKQAENDKEVRRLARSQERQLRTWLYGATGYGGSSRAGGADADTDAPPAEPTSAKTLAEVVSEVCGEVEDTFAIKVQQVVVGDCEVDDRVLAAVWAAREAMVNAAKHAEVGEVSVFVEIEPEQIELFVRDRGKGFDPTTVSQDRHGLADSIHGRMERHGGTVRLRTAPGEGTEVALRLPRTGDKR
>NZ_CP014859.1|WP_084643421.1|5778690_5780088_+|PspC-domain-containing-protein
MGSAGPARPAGSTSTGEGRFEDNIRDMWRTRPVRRSDDRKIAGVAAGIARRYDLDPTLVRVVLVVTSFYGGCGILIYLLGWLFLRQQNELSSPAEALAGRGRRTATLLGAIMLPALLVMAIIPIMGWVLSNAFTSAVCLGGVGVALYLLHVQRRDTGQPTVNWPQTAHVVDDFHSAAEAPTTAFGTPAAAPFTPESEVGYPTDRFPGSPTAGTAQQRAGEPEPPAWDPLGVAPFAWQLPDPVDHRAPAPEPEPAPAPTRRVRSRVTPITIGAALLTFAIGMPLLESAGWLTQPRMLALILAVLGIGMVVGAFRSGGRGLIWVSAPIAAVAMLVSLVPIHETGGWLDAGSTHLRVSEPEQLRDAYRRSLGAIELDLTELTIPEGETLRTEVMLNLGGNIEVIVPPDMAVSATCQVRLGGMSCLGEENYGENEQIHVADRPDGPDSAGGTLELDAYLGLGELNVTRR
>NZ_CP014859.1|WP_069852452.1|5780071_5780302_+|hypothetical-protein
MSRGAERRDRKRASLRGPRDLLTLVSGVIALLVAGYVLANSIGWVPLYQARWLLAAGAVIIGLVLLLGSLRSRREE
>NZ_CP014859.1|WP_069854108.1|5780363_5781389_+|LacI-family-DNA-binding-transcriptional-regulator
MQPSGEHRPTLEDVAALAGVSRATVSRVVNNSPRVSPEAKDSVYSAIRELGYVPNRAARTLVTRRTGAVAVVISEPESKIFDDPRFATVVRAAANRLGELDAAMVLMLVHSPADEARIERFLLGGHVDGALLFTPHRGDPLPTAMAALPIPTVFGGRPWTANGSLHLVDTDNREGGRIGTQHLLDLGRKRVVSVTGPLDEHAAIDRLEGWRLAIGADEAATARLTESGHFAREGGKQAMYRLLERVPDLDGVFAASDLMAAGAIDALTTAGRRVPQDVAVVGFDDQPAVAPHTNPPLTTIAQDASEQVRRMVHRLTRLIAGEDLAGGMEVLPVHLVRRASA
>NZ_CP014859.1|WP_069852454.1|5781502_5783071_-|glutamine-hydrolyzing-GMP-synthase
MPSSAKGPVLVVDFGAQYAQLIARRVREAQVYSEVVPHSTPTAELLARDPAAVVLSGGPASVYADEAPDLDPELLTSGVPVFGICYGFQAMARALGGTVAHTGSREYGRTDLESDGGVLHTDLPGRHPVWMSHGDAVTEAPAGFAVTASSAGAPVAAFEDVDRRLAGVQYHPEVAHSPHGQEVLRRFLRDVAGLGPDWTTASIVEEQVELIRKQIGSGRVICALSGGVDSAVAAALVQRAVGDQLTCVFVDHGLLRSGERSQVEQDLVAATGVRLVTVDAKDRFLDALAGVTDPEQKRKIIGREFIRVFEQAARDLQAEAGEHGTSVDFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPDDLQFELVEPLRALFKDEVRRVGLELGLPETIVQRQPFPGPGLGIRIIGEVTAERLETLRAADAIVREELTSAGLDREIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWMRMPYEVLERISTRVTNEVPEVNRVTLDVTSKPPGTIEWE
>NZ_CP014859.1|WP_069852456.1|5783264_5784677_+|aldehyde-dehydrogenase-family-protein
MDAFVPTPRPSWIAGNAEPNDRRQEVRHPYDETEVATICVPDADQIWRAVQGTVAATREIAAVSPHSRTAVLNAVAEGISERAEEFAEIITAENGKPLRWAEVEVAAAASVFRLAAAAVDAGAGEPNRWTSGVLARRTPRGPVLAMTSAEYPLASAARQVAAAIAAGCPVLVAPPLRTPLAALMLGELLAEVDLVDGAFSVLPVDEEATRALADDQRASVLSVSGAREVSAHRIVAGRHLVLELGGVTTALICADWAAPADLDRAADRIAEFGTHQAGQSVAALQRVLVDASVYAEFLPRLVAAMRKLRTGDPHDPEVQVGPLIDEAAAREVHARITEAVEAGAEIVVGGDRSGTTVEPTVLTGVPSTSRLWREPVFGPVLVVSAAADLQAAFAQVEDAPILGRASVFTHDLRVAFQAGTALAVEELVVGDVPAPEARGAAGDDPDRDGLHRLLVEFTVERRTVFAAELP
>NZ_CP014859.1|WP_069852458.1|5784798_5785440_-|NAD(P)H-binding-protein
MRITLFGTTGSVGGRVLAEALSRGHEVLAVIRDARRRGGLPSQVRTRVGDVRQAADVAAASAGQDVVISATRPVSGREHELTESAEALLAGAAQSGVRLILVGGAAGLIVPGTDGATVVEDPDFPTELRAIALACDDQLAACRADLGGADWAYLSPPALLEPGERTGRYRLGADELLVDAAGDSRISLEDFAVALVDEAERPKHHRTRFTVGY
>NZ_CP014859.1|WP_084643423.1|5785470_5786487_-|EamA-family-transporter
MLSNRVGVLALTALAPAIWGSTYLVTTELLPPGRPLLAAVIRSLPAGLLLLAITRKLPQGSWWWRSLVLGGLNIGAFLALLFIAAYRLPGGVAATVGAVQPLLVAFFAAGLLGQQLSRRTLIAATAGIAGVALLVLRAQARLDAVGLLAAFGGAVVMAVGVVLSKRWTSTAPLLLASTGWQLIAGGTLLLPVALLVEGPPPTTLTGQNLLGYGYLMLIGAALSYALWFRGIWLLPATDVTFLTLLSPLVATALGWVVLGEELTGAQLVGALVVLGALIAAQRPKPTDAGKPAATSEPGTDQWVPVGGASANPRPRPKSHNVPARSPVPEPTDPQQPAR
>NZ_CP014859.1|WP_157421290.1|5786558_5787056_+|MarR-family-transcriptional-regulator
MADHVDRVLEQWAAQRPDLDVSPMAVIGRLSRVKQLVDADMRRTFAAHGLDRASFDVLATLRRSNPPHRLTPAELMRSAMVTSGAITQRLDRLQDRGLVTRAPSESDGRGVQVALTDEGLTLVDRVLPDHLATEQRLLAGLSATQRETLAGALRELLESLGDDVR

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP014859_2	2.1|364922|19|NZ_CP014859|CRT	364922-364940	19	NZ_CP014859.1	2830761-2830779	2	0.895

1. spacer 2.1|364922|19|NZ_CP014859|CRT matches to position: 2830761-2830779, mismatch: 2, identity: 0.895

tgaggacgacgatgccggg	CRISPR spacer
tgacgtcgacgatgccggg	Protospacer
*** * *************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK359354	Mycobacterium phage PinkPlastic, complete genome	40381-40412	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH576959	Mycobacterium phage Pita2, complete genome	40765-40796	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK112532	Mycobacterium phage Bones, complete genome	41448-41479	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MG925344	Mycobacterium phage Ichabod, complete genome	41588-41619	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MT889384	Mycobacterium phage STLscum, complete genome	41364-41395	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK359299	Mycobacterium phage Petp2012, complete genome	42416-42447	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MG920060	Mycobacterium phage Bob3, complete genome	40224-40255	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	AY500152	Mycobacteriophage U2, complete genome	41054-41085	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	EU744251	Mycobacterium phage Jasper, complete genome	39434-39465	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MG925351	Mycobacterium phage MPlant7149, complete genome	39349-39380	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK820638	Mycobacterium phage HermioneGrange, complete genome	41461-41492	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	AY500153	Mycobacteriophage Bethlehem, complete genome	41906-41937	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH590595	Mycobacterium phage NEHalo, complete genome	40288-40319	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK359304	Mycobacterium phage SpikeBT, complete genome	40145-40176	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK305893	Mycobacterium phage Beatrix, complete genome	41353-41384	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	KT438500	Mycobacterium phage Pari, complete genome	40216-40247	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	KJ690250	Mycobacterium phage Pinto, complete genome	40568-40599	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_023862	Mycobacterium phage Alsfro, complete genome	40496-40527	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	JN398369	Mycobacterium phage RidgeCB, complete genome	40544-40575	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_009877	Mycobacterium phage U2, complete genome	41054-41085	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MN813700	Mycobacterium phage Atkinbua, complete genome	40686-40717	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	EU744249	Mycobacterium phage Lockley, complete genome	39840-39871	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	KF560331	Mycobacterium phage Graduation, complete genome	41720-41751	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MT639654	Mycobacterium phage Jerm2, complete genome	41716-41747	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	JN660814	Mycobacterium phage Dreamboat, complete genome	39548-39579	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_031067	Mycobacterium phage Makemake, complete genome	41822-41853	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH669011	Mycobacterium phage PherrisBueller, complete genome	39085-39116	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH576971	Mycobacterium phage Arlo, complete genome	40258-40289	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK359300	Mycobacterium phage AFIS, complete genome	39220-39251	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH450113	Mycobacterium phage BigMau, complete genome	40967-40998	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH020236	Mycobacterium phage GageAP, complete genome	40887-40918	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_042327	Mycobacterium virus BBPiebs31, complete genome	41175-41206	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MN444869	Mycobacterium phage DreamCatcher, complete genome	41318-41349	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	EU744252	Mycobacterium phage DD5, complete genome	40678-40709	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH020244	Mycobacterium phage Lopton, complete genome	42233-42264	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	KT259047	Mycobacterium phage Rufus, complete genome	41045-41076	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK359316	Mycobacterium phage Cueylyss, complete genome	41648-41679	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_009878	Mycobacterium phage Bethlehem, complete genome	41906-41937	5	0.844
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MH450130	Mycobacterium phage Rohr, complete genome	41762-41793	5	0.844
NZ_CP014859_8	8.1|1316469|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	1316469-1316501	33	NZ_CP011453	Altererythrobacter atlanticus strain 26DY36 plasmid unnamed, complete sequence	71370-71402	5	0.848
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NZ_CP009572	Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence	58102-58130	5	0.828
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	332653-332681	5	0.828
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MH719191	Pseudomonas phage Fc22, complete genome	2032-2063	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MH719194	Pseudomonas phage Ps60, complete genome	1845-1876	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_006548	Pseudomonas phage B3, complete genome	2010-2041	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MK511059	Pseudomonas phage CF78, partial genome	1886-1917	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MK511062	Pseudomonas phage CF127, partial genome	1890-1921	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	AF232233	Bacteriophage B3, complete genome	2010-2041	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MK511061	Pseudomonas phage CF125, partial genome	1885-1916	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_027992	Pseudomonas phage JBD25, complete genome	2370-2401	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	LN898172	Pseudomonas phage vB_PaeS_PM105	1816-1847	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MK511063	Pseudomonas phage CF177, partial genome	1008-1039	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MH719192	Pseudomonas phage Ps56, complete genome	2371-2402	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MN536027	Pseudomonas phage vB_Pae-SS2019XII, complete genome	26339-26370	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	KM389239	UNVERIFIED: Pseudomonas phage F_HA1208sp/Pa1651 clone contig00003 genomic sequence	7895-7926	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MK934841	Pseudomonas phage UMP151, complete genome	2167-2198	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MH719193	Pseudomonas phage H72, complete genome	2371-2402	5	0.844
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	JX495041	Pseudomonas phage JBD18, complete genome	1823-1854	5	0.844
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	KX855962	Arthrobacter phage HumptyDumpty, complete genome	18888-18921	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MF185721	Arthrobacter phage Kabreeze, complete genome	18888-18921	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	KX522650	Arthrobacter Phage Conboy, complete genome	18889-18922	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MN204503	Arthrobacter phage Linus, complete genome	18888-18921	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MF185723	Arthrobacter phage RosiePosie, complete genome	18891-18924	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	KX670787	Arthrobacter phage Chocolat, complete genome	18891-18924	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MF668274	Arthrobacter phage JayCookie, complete genome	18891-18924	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MK494107	Arthrobacter phage Chipper1996, complete genome	18890-18923	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MF185724	Arthrobacter phage Scavito, complete genome	18888-18921	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	KX670786	Arthrobacter phage Chubster, complete genome	18661-18694	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MN204499	Arthrobacter phage Mordred, complete genome	18888-18921	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	MF185725	Arthrobacter phage Tophat, complete genome	18890-18923	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	KU160660	Arthrobacter phage PrincessTrina, complete genome	18891-18924	6	0.824
NZ_CP014859_4	4.10|1200723|34|NZ_CP014859|CRISPRCasFinder	1200723-1200756	34	KX855961	Arthrobacter phage EdgarPoe, complete genome	18889-18922	6	0.824
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_LR134460	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 18, complete sequence	16378-16409	6	0.812
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MN369760	Mycobacterium phage KyMonks1A, complete genome	40440-40471	6	0.812
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK112540	Mycobacterium phage Froghopper, complete genome	39019-39050	6	0.812
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_042326	Mycobacterium virus KSSJEB, complete genome	39862-39893	6	0.812
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_028941	Mycobacterium phage Turj99, complete genome	41336-41367	6	0.812
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK359354	Mycobacterium phage PinkPlastic, complete genome	40381-40413	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH576959	Mycobacterium phage Pita2, complete genome	40765-40797	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK112532	Mycobacterium phage Bones, complete genome	41448-41480	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MG925344	Mycobacterium phage Ichabod, complete genome	41588-41620	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MT889384	Mycobacterium phage STLscum, complete genome	41364-41396	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK359299	Mycobacterium phage Petp2012, complete genome	42416-42448	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MG920060	Mycobacterium phage Bob3, complete genome	40224-40256	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	AY500152	Mycobacteriophage U2, complete genome	41054-41086	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	EU744251	Mycobacterium phage Jasper, complete genome	39434-39466	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MG925351	Mycobacterium phage MPlant7149, complete genome	39349-39381	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK820638	Mycobacterium phage HermioneGrange, complete genome	41461-41493	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	AY500153	Mycobacteriophage Bethlehem, complete genome	41906-41938	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH590595	Mycobacterium phage NEHalo, complete genome	40288-40320	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK359304	Mycobacterium phage SpikeBT, complete genome	40145-40177	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK305893	Mycobacterium phage Beatrix, complete genome	41353-41385	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	KT438500	Mycobacterium phage Pari, complete genome	40216-40248	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	KJ690250	Mycobacterium phage Pinto, complete genome	40568-40600	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_023862	Mycobacterium phage Alsfro, complete genome	40496-40528	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	JN398369	Mycobacterium phage RidgeCB, complete genome	40544-40576	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_009877	Mycobacterium phage U2, complete genome	41054-41086	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MN813700	Mycobacterium phage Atkinbua, complete genome	40686-40718	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	EU744249	Mycobacterium phage Lockley, complete genome	39840-39872	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	KF560331	Mycobacterium phage Graduation, complete genome	41720-41752	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MT639654	Mycobacterium phage Jerm2, complete genome	41716-41748	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	JN660814	Mycobacterium phage Dreamboat, complete genome	39548-39580	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_031067	Mycobacterium phage Makemake, complete genome	41822-41854	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH669011	Mycobacterium phage PherrisBueller, complete genome	39085-39117	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH576971	Mycobacterium phage Arlo, complete genome	40258-40290	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK359300	Mycobacterium phage AFIS, complete genome	39220-39252	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH450113	Mycobacterium phage BigMau, complete genome	40967-40999	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH020236	Mycobacterium phage GageAP, complete genome	40887-40919	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_042327	Mycobacterium virus BBPiebs31, complete genome	41175-41207	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MN444869	Mycobacterium phage DreamCatcher, complete genome	41318-41350	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	EU744252	Mycobacterium phage DD5, complete genome	40678-40710	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH020244	Mycobacterium phage Lopton, complete genome	42233-42265	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	KT259047	Mycobacterium phage Rufus, complete genome	41045-41077	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK359316	Mycobacterium phage Cueylyss, complete genome	41648-41680	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_009878	Mycobacterium phage Bethlehem, complete genome	41906-41938	6	0.818
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MH450130	Mycobacterium phage Rohr, complete genome	41762-41794	6	0.818
NZ_CP014859_7	7.2|1312532|31|NZ_CP014859|PILER-CR	1312532-1312562	31	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	268961-268991	6	0.806
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	825403-825431	6	0.793
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	572593-572621	6	0.793
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	76748-76776	6	0.793
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	133046-133074	6	0.793
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	CP047390	Agrobacterium sp. CGMCC 11546 plasmid pB	205477-205509	6	0.818
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP033036	Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence	251404-251436	6	0.818
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_003064	Agrobacterium fabrum str. C58 plasmid At, complete sequence	418318-418350	6	0.818
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP033024	Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence	181421-181453	6	0.818
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	HQ332141	Halorubrum phage CGphi46 genomic sequence	21661-21692	6	0.812
NZ_CP014859_16	16.8|5411536|32|NZ_CP014859|PILER-CR	5411536-5411567	32	NZ_CP016080	Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence	204221-204252	6	0.812
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MK977702	Gordonia terrae phage McKinley, complete genome	30171-30206	7	0.806
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MK977702	Gordonia terrae phage McKinley, complete genome	30171-30206	7	0.806
NZ_CP014859_5	5.2|1279849|34|NZ_CP014859|CRISPRCasFinder	1279849-1279882	34	NZ_CP013856	Pseudonocardia sp. HH130630-07 plasmid pLS2-2, complete sequence	35766-35799	7	0.794
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MF324902	Rhodococcus phage Krishelle, complete genome	24890-24921	7	0.781
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MF324903	Rhodococcus phage AppleCloud, complete genome	24548-24579	7	0.781
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_LR134460	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 18, complete sequence	16378-16410	7	0.788
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MN369760	Mycobacterium phage KyMonks1A, complete genome	40440-40472	7	0.788
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	MK112540	Mycobacterium phage Froghopper, complete genome	39019-39051	7	0.788
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_042326	Mycobacterium virus KSSJEB, complete genome	39862-39894	7	0.788
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_028941	Mycobacterium phage Turj99, complete genome	41336-41368	7	0.788
NZ_CP014859_7	7.2|1312532|31|NZ_CP014859|PILER-CR	1312532-1312562	31	MN284893	Mycobacterium phage LilMcDreamy, complete genome	45745-45775	7	0.774
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	17117-17145	7	0.759
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP030828	Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence	531450-531482	7	0.788
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	290880-290912	7	0.788
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP016500	Agrobacterium sp. RAC06 plasmid pBSY240_1, complete sequence	276327-276359	7	0.788
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP045856	Agrobacterium sp. MA01 plasmid punanmed2, complete sequence	8889-8921	7	0.788
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_015184	Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence	337853-337885	7	0.788
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP015091	Pelagibaca abyssi strain JLT2014 plasmid pPABY1, complete sequence	237576-237607	7	0.781
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	MT889367	Gordonia phage Orla, complete genome	15786-15817	7	0.781
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP015091	Pelagibaca abyssi strain JLT2014 plasmid pPABY1, complete sequence	237576-237608	7	0.788
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	MT889367	Gordonia phage Orla, complete genome	15786-15818	7	0.788
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP013635	Rhizobium sp. N324 plasmid pRspN324e, complete sequence	148901-148932	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_LR536451	Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 2	237863-237894	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP015203	Rhodococcus sp. 008 plasmid pR8L1, complete sequence	18808-18839	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP044283	Rhodococcus erythropolis strain X5 plasmid pRhX5, complete sequence	502622-502653	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP011297	Rhodococcus erythropolis strain BG43 plasmid pRLLBG43, complete sequence	72183-72214	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP014942	Rhodococcus sp. BH4 plasmid, complete sequence	22501-22532	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP017300	Rhodococcus sp. YL-1 plasmid pYLC1, complete sequence	11218-11249	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	425845-425876	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	KY555147	Caulobacter phage Ccr34, complete genome	58768-58799	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_019410	Caulobacter phage CcrKarma, complete genome	58433-58464	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	KY555146	Caulobacter phage Ccr32, complete genome	58327-58358	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_019407	Caulobacter phage CcrMagneto, complete genome	57025-57056	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	JX163858	Caulobacter phage phiCbK, complete genome	149499-149530	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_019411	Caulobacter phage CcrSwift, complete genome	57582-57613	7	0.781
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1722302-1722333	7	0.781
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MK977702	Gordonia terrae phage McKinley, complete genome	30170-30206	8	0.784
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5224319-5224355	8	0.784
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MK977702	Gordonia terrae phage McKinley, complete genome	30170-30206	8	0.784
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5224319-5224355	8	0.784
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	390157-390192	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MK937601	Gordonia phage Charming, complete genome	28718-28753	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH976519	Gordonia phage Tangent, complete genome	28721-28756	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH976510	Gordonia phage Fosterous, complete genome	29134-29169	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH976518	Gordonia phage Stultus, complete genome	28284-28319	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH479924	Gordonia phage Rofo, complete genome	29199-29234	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MK937594	Gordonia phage Galadriel, complete genome	29623-29658	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MN329673	Gordonia phage Jabberwocky, complete genome	29762-29797	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH651166	Gordonia phage Angelicage, complete genome	29461-29496	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MT639640	Gordonia phage Paries, complete genome	29801-29836	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	NC_042108	Gordonia phage Brandonk123, complete genome	29209-29244	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH976514	Gordonia phage Nordenberg, complete genome	28335-28370	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH976507	Gordonia phage Ailee, complete genome	29543-29578	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MT498035	Gordonia Phage Barsten, complete genome	28675-28710	8	0.778
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	NC_031239	Gordonia phage Vivi2, complete genome	29888-29923	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	390157-390192	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MK937601	Gordonia phage Charming, complete genome	28718-28753	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH976519	Gordonia phage Tangent, complete genome	28721-28756	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH976510	Gordonia phage Fosterous, complete genome	29134-29169	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH976518	Gordonia phage Stultus, complete genome	28284-28319	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH479924	Gordonia phage Rofo, complete genome	29199-29234	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MK937594	Gordonia phage Galadriel, complete genome	29623-29658	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MN329673	Gordonia phage Jabberwocky, complete genome	29762-29797	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH651166	Gordonia phage Angelicage, complete genome	29461-29496	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MT639640	Gordonia phage Paries, complete genome	29801-29836	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	NC_042108	Gordonia phage Brandonk123, complete genome	29209-29244	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH976514	Gordonia phage Nordenberg, complete genome	28335-28370	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH976507	Gordonia phage Ailee, complete genome	29543-29578	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MT498035	Gordonia Phage Barsten, complete genome	28675-28710	8	0.778
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	NC_031239	Gordonia phage Vivi2, complete genome	29888-29923	8	0.778
NZ_CP014859_5	5.2|1279849|34|NZ_CP014859|CRISPRCasFinder	1279849-1279882	34	NZ_CP032827	Sphingomonas sp. YZ-8 plasmid unnamed2, complete sequence	71359-71392	8	0.765
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1787540-1787571	8	0.75
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP020911	Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence	749603-749634	8	0.75
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	720346-720377	8	0.75
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	377142-377173	8	0.75
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	79871-79902	8	0.75
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	263732-263763	8	0.75
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	263732-263764	8	0.758
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP020911	Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence	749602-749634	8	0.758
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	377142-377174	8	0.758
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	79870-79902	8	0.758
NZ_CP014859_7	7.1|1312471|31|NZ_CP014859|PILER-CR	1312471-1312501	31	NZ_CP047657	Paraglaciecola mesophila strain GPM4 plasmid unnamed	68876-68906	8	0.742
NZ_CP014859_7	7.4|1312531|33|NZ_CP014859|CRISPRCasFinder	1312531-1312563	33	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	268960-268992	8	0.758
NZ_CP014859_7	7.4|1312531|33|NZ_CP014859|CRISPRCasFinder	1312531-1312563	33	MN284893	Mycobacterium phage LilMcDreamy, complete genome	45744-45776	8	0.758
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	36217-36245	8	0.724
NZ_CP014859_8	8.3|1316591|29|NZ_CP014859|CRT	1316591-1316619	29	NC_008697	Nocardioides sp. JS614 plasmid pNOCA01, complete sequence	93280-93308	8	0.724
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	1166292-1166324	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	1297212-1297244	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	1272305-1272337	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_015597	Sinorhizobium meliloti AK83 plasmid pSINME01, complete sequence	181345-181377	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	1179535-1179567	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	868649-868681	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	1279731-1279763	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	376200-376232	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	311343-311375	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	902367-902399	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP019483	Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence	1018225-1018257	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	972471-972503	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	1164630-1164662	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	213784-213816	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	916392-916424	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	577058-577090	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	347637-347669	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	314072-314104	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	484634-484666	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_018022	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence	361853-361885	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1486362-1486394	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NC_008703	Mycobacterium sp. KMS plasmid pMKMS01, complete sequence	257690-257722	8	0.758
NZ_CP014859_10	10.4|3825081|33|NZ_CP014859|CRISPRCasFinder	3825081-3825113	33	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	213914-213946	8	0.758
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	290880-290916	8	0.784
NZ_CP014859_11	11.1|3877203|32|NZ_CP014859|PILER-CR,CRT	3877203-3877234	32	MT639639	Gordonia phage LittleFella, complete genome	33817-33848	8	0.75
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	666116-666147	8	0.75
NZ_CP014859_13	13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574448-4574480	33	NZ_CP015369	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p2, complete sequence	27177-27209	8	0.758
NZ_CP014859_13	13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574448-4574480	33	NZ_JX627582	Methylobacterium oryzae CBMB20 plasmid pMOC3, complete sequence	15910-15942	8	0.758
NZ_CP014859_13	13.4|4574509|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574509-4574541	33	NZ_CP047145	Streptomyces sp. HF10 plasmid plas1, complete sequence	83998-84030	8	0.758
NZ_CP014859_13	13.7|4574692|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574692-4574724	33	NZ_CP049032	Fluviibacterium aquatile strain SC52 plasmid pSC52_4, complete sequence	16231-16263	8	0.758
NZ_CP014859_13	13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574753-4574785	33	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	268629-268661	8	0.758
NZ_CP014859_13	13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574753-4574785	33	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	359649-359681	8	0.758
NZ_CP014859_13	13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574753-4574785	33	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	442593-442625	8	0.758
NZ_CP014859_13	13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574753-4574785	33	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	315405-315437	8	0.758
NZ_CP014859_13	13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574753-4574785	33	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	336459-336491	8	0.758
NZ_CP014859_13	13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574753-4574785	33	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	382767-382799	8	0.758
NZ_CP014859_13	13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574753-4574785	33	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	389093-389125	8	0.758
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP050081	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence	648245-648276	8	0.75
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP050098	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence	808199-808230	8	0.75
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP049731	Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence	682476-682507	8	0.75
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	901611-901642	8	0.75
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP053206	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence	683667-683698	8	0.75
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	2966-2997	8	0.75
NZ_CP014859_16	16.10|5411658|32|NZ_CP014859|PILER-CR	5411658-5411689	32	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	112075-112106	8	0.75
NZ_CP014859_16	16.10|5411658|32|NZ_CP014859|PILER-CR	5411658-5411689	32	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	76089-76120	8	0.75
NZ_CP014859_16	16.10|5411658|32|NZ_CP014859|PILER-CR	5411658-5411689	32	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	1172001-1172032	8	0.75
NZ_CP014859_16	16.10|5411658|32|NZ_CP014859|PILER-CR	5411658-5411689	32	NC_009621	Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence	1038510-1038541	8	0.75
NZ_CP014859_17	17.1|5551084|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551084-5551116	33	JQ680367	Unidentified phage clone 2203_scaffold802 genomic sequence	6915-6947	8	0.758
NZ_CP014859_17	17.3|5551206|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551206-5551238	33	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	681589-681621	8	0.758
NZ_CP014859_18	18.4|5553663|33|NZ_CP014859|PILER-CR,CRT	5553663-5553695	33	NZ_CP053208	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1B, complete sequence	141658-141690	8	0.758
NZ_CP014859_18	18.8|5553664|32|NZ_CP014859|CRISPRCasFinder	5553664-5553695	32	NZ_CP053208	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1B, complete sequence	141659-141690	8	0.75
NZ_CP014859_19	19.1|5776183|33|NZ_CP014859|PILER-CR	5776183-5776215	33	MH884510	Exiguobacterium phage vB_EalM-137, complete genome	25147-25179	8	0.758
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	NZ_CP015744	Shinella sp. HZN7 plasmid pShin-08, complete sequence	67372-67401	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MG962374	Mycobacterium phage Paola, complete genome	5691-5720	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	KX585251	Mycobacterium phage Waterfoul, complete genome	5713-5742	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MH051255	Mycobacterium phage Leston, complete genome	5716-5745	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	KX636165	Mycobacterium phage Gengar, complete genome	5716-5745	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MF185720	Mycobacterium phage Guillsminger, complete genome	5691-5720	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	NC_024366	Mycobacterium phage OkiRoe, complete genome	5692-5721	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	NC_023724	Mycobacterium phage Larva, complete genome	5466-5495	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MH651171	Mycobacterium phage Collard, complete genome	5690-5719	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MH576966	Mycobacterium phage Thyatira, complete genome	5691-5720	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MF185717	Mycobacterium phage AlleyCat, complete genome	5725-5754	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MK376961	Gordonia phage Asapag, complete genome	38818-38847	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	NC_028947	Mycobacterium phage Kratio, complete genome	5464-5493	8	0.733
NZ_CP014859_19	19.2|5776247|30|NZ_CP014859|PILER-CR	5776247-5776276	30	MF185719	Mycobacterium phage Edugator, complete genome	5725-5754	8	0.733
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	390156-390192	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MK937601	Gordonia phage Charming, complete genome	28717-28753	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH976519	Gordonia phage Tangent, complete genome	28720-28756	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH976510	Gordonia phage Fosterous, complete genome	29133-29169	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH976518	Gordonia phage Stultus, complete genome	28283-28319	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH479924	Gordonia phage Rofo, complete genome	29198-29234	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MK937594	Gordonia phage Galadriel, complete genome	29622-29658	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MN329673	Gordonia phage Jabberwocky, complete genome	29761-29797	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH651166	Gordonia phage Angelicage, complete genome	29460-29496	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MT639640	Gordonia phage Paries, complete genome	29800-29836	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	NC_042108	Gordonia phage Brandonk123, complete genome	29208-29244	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH976514	Gordonia phage Nordenberg, complete genome	28334-28370	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH976507	Gordonia phage Ailee, complete genome	29542-29578	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MT498035	Gordonia Phage Barsten, complete genome	28674-28710	9	0.757
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	NC_031239	Gordonia phage Vivi2, complete genome	29887-29923	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	390156-390192	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MK937601	Gordonia phage Charming, complete genome	28717-28753	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH976519	Gordonia phage Tangent, complete genome	28720-28756	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH976510	Gordonia phage Fosterous, complete genome	29133-29169	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH976518	Gordonia phage Stultus, complete genome	28283-28319	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH479924	Gordonia phage Rofo, complete genome	29198-29234	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MK937594	Gordonia phage Galadriel, complete genome	29622-29658	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MN329673	Gordonia phage Jabberwocky, complete genome	29761-29797	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH651166	Gordonia phage Angelicage, complete genome	29460-29496	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MT639640	Gordonia phage Paries, complete genome	29800-29836	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	NC_042108	Gordonia phage Brandonk123, complete genome	29208-29244	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH976514	Gordonia phage Nordenberg, complete genome	28334-28370	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH976507	Gordonia phage Ailee, complete genome	29542-29578	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MT498035	Gordonia Phage Barsten, complete genome	28674-28710	9	0.757
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	NC_031239	Gordonia phage Vivi2, complete genome	29887-29923	9	0.757
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5224319-5224354	9	0.75
NZ_CP014859_4	4.11|1200795|36|NZ_CP014859|CRISPRCasFinder	1200795-1200830	36	MH976512	Gordonia phage Geodirt, complete genome	28609-28644	9	0.75
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5224319-5224354	9	0.75
NZ_CP014859_4	4.13|1200943|36|NZ_CP014859|CRISPRCasFinder	1200943-1200978	36	MH976512	Gordonia phage Geodirt, complete genome	28609-28644	9	0.75
NZ_CP014859_5	5.2|1279849|34|NZ_CP014859|CRISPRCasFinder	1279849-1279882	34	NZ_CP032326	Azospirillum brasilense strain MTCC4035 plasmid p5, complete sequence	101776-101809	9	0.735
NZ_CP014859_5	5.2|1279849|34|NZ_CP014859|CRISPRCasFinder	1279849-1279882	34	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1267817-1267850	9	0.735
NZ_CP014859_5	5.2|1279849|34|NZ_CP014859|CRISPRCasFinder	1279849-1279882	34	MT889392	Microbacterium phage Lahqtemish, complete genome	31181-31214	9	0.735
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	491875-491906	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	1239786-1239817	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	1211828-1211859	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	1307333-1307364	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	486899-486930	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	812925-812956	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	835902-835933	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	739997-740028	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	928112-928143	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	503637-503668	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1380159-1380190	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	1152822-1152853	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	1239792-1239823	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021332	Maritalea myrionectae strain HL2708#5 plasmid pHL2708Y3, complete sequence	130865-130896	9	0.719
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	961848-961879	9	0.719
NZ_CP014859_6	6.2|1281414|32|NZ_CP014859|PILER-CR	1281414-1281445	32	NZ_CP034431	Bradyrhizobium sp. LCT2 plasmid pLCT2, complete sequence	70238-70269	9	0.719
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1787540-1787572	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	720345-720377	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	491875-491907	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	1239785-1239817	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	1211827-1211859	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	1307332-1307364	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	486899-486931	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	812924-812956	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	835902-835934	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	739997-740029	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	928111-928143	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	503637-503669	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1380158-1380190	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	1152821-1152853	9	0.727
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	1239791-1239823	9	0.727
NZ_CP014859_7	7.1|1312471|31|NZ_CP014859|PILER-CR	1312471-1312501	31	NZ_CP029540	Aquitalea sp. USM4 plasmid unnamed, complete sequence	35561-35591	9	0.71
NZ_CP014859_8	8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	1316530-1316562	33	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	107825-107857	9	0.727
NZ_CP014859_8	8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	1316530-1316562	33	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1548084-1548116	9	0.727
NZ_CP014859_8	8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	1316530-1316562	33	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1298643-1298675	9	0.727
NZ_CP014859_8	8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	1316530-1316562	33	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1548086-1548118	9	0.727
NZ_CP014859_10	10.3|3825020|33|NZ_CP014859|PILER-CR,CRISPRCasFinder	3825020-3825052	33	MN234219	Mycobacterium phage Mercurio, complete genome	4098-4130	9	0.727
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	1166288-1166324	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	1297208-1297244	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	CP047390	Agrobacterium sp. CGMCC 11546 plasmid pB	205473-205509	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	1272301-1272337	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NC_015597	Sinorhizobium meliloti AK83 plasmid pSINME01, complete sequence	181341-181377	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	1179531-1179567	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	868645-868681	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	1279727-1279763	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	376196-376232	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	311339-311375	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	902363-902399	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP030828	Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence	531446-531482	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP019483	Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence	1018221-1018257	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	972467-972503	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	1164626-1164662	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	213784-213820	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	916392-916428	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	577058-577094	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP033036	Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence	251404-251440	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	347637-347673	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NC_003064	Agrobacterium fabrum str. C58 plasmid At, complete sequence	418318-418354	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	314072-314108	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	484634-484670	9	0.757
NZ_CP014859_10	10.8|3825077|37|NZ_CP014859|CRT	3825077-3825113	37	NZ_CP033024	Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence	181421-181457	9	0.757
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013634	Rhizobium sp. N324 plasmid pRspN324d, complete sequence	343072-343103	9	0.719
NZ_CP014859_13	13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574448-4574480	33	NZ_CP011515	Mitsuaria sp. 7 plasmid, complete sequence	21006-21038	9	0.727
NZ_CP014859_13	13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR	4574448-4574480	33	KJ410133	Mycobacterium phage Jolie2, complete genome	13689-13721	9	0.727
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	31878-31909	9	0.719
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	336746-336777	9	0.719
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_008757	Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence	309023-309054	9	0.719
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	257635-257666	9	0.719
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	MK305891	Streptomyces phage Gibson, complete genome	56697-56728	9	0.719
NZ_CP014859_16	16.7|5411840|33|NZ_CP014859|CRISPRCasFinder,CRT	5411840-5411872	33	NC_019387	Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence	153555-153587	9	0.727
NZ_CP014859_16	16.7|5411840|33|NZ_CP014859|CRISPRCasFinder,CRT	5411840-5411872	33	NZ_CP015268	Mycobacterium chimaera strain ZUERICH-2 plasmid unnamed 1, complete sequence	105031-105063	9	0.727
NZ_CP014859_16	16.10|5411658|32|NZ_CP014859|PILER-CR	5411658-5411689	32	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1311563-1311594	9	0.719
NZ_CP014859_17	17.2|5551145|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551145-5551177	33	NZ_CP017079	Novosphingobium resinovorum strain SA1 plasmid pSA4, complete sequence	23270-23302	9	0.727
NZ_CP014859_17	17.2|5551145|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551145-5551177	33	NZ_CP013073	Sphingobium indicum B90A plasmid pSRL3, complete sequence	25636-25668	9	0.727
NZ_CP014859_17	17.2|5551145|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551145-5551177	33	NZ_CP005190	Sphingobium sp. MI1205 plasmid pMI1, complete sequence	66576-66608	9	0.727
NZ_CP014859_17	17.3|5551206|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551206-5551238	33	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	201999-202031	9	0.727
NZ_CP014859_2	2.5|365200|37|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder	365200-365236	37	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	463252-463288	10	0.73
NZ_CP014859_2	2.8|365422|37|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder	365422-365458	37	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	463252-463288	10	0.73
NZ_CP014859_3	3.2|1157655|37|NZ_CP014859|PILER-CR	1157655-1157691	37	KR053197	Gordonia phage GRU3, complete genome	15543-15579	10	0.73
NZ_CP014859_4	4.2|1200794|37|NZ_CP014859|PILER-CR,CRT	1200794-1200830	37	MH976512	Gordonia phage Geodirt, complete genome	28608-28644	10	0.73
NZ_CP014859_4	4.4|1200942|37|NZ_CP014859|PILER-CR,CRT	1200942-1200978	37	MH976512	Gordonia phage Geodirt, complete genome	28608-28644	10	0.73
NZ_CP014859_4	4.17|1201237|34|NZ_CP014859|CRISPRCasFinder	1201237-1201270	34	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	216287-216320	10	0.706
NZ_CP014859_4	4.17|1201237|34|NZ_CP014859|CRISPRCasFinder	1201237-1201270	34	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	169719-169752	10	0.706
NZ_CP014859_5	5.2|1279849|34|NZ_CP014859|CRISPRCasFinder	1279849-1279882	34	NZ_CP021919	Sagittula sp. P11 plasmid unnamed5, complete sequence	8243-8276	10	0.706
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_010311	Streptomyces sp. HK1 plasmid pSHK1, complete sequence	157157-157188	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	481368-481399	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	74839-74870	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP029339	Streptomyces sp. SM17 plasmid pSM17A, complete sequence	25274-25305	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	479011-479042	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1145920-1145951	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	365854-365885	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	450105-450136	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1267804-1267835	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	528651-528682	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	630392-630423	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK962628	Achromobacter phage vB_AxyP_19-32_Axy09, complete genome	25266-25297	10	0.688
NZ_CP014859_6	6.1|1281353|32|NZ_CP014859|PILER-CR	1281353-1281384	32	MK962640	Achromobacter phage vB_AxyP_19-32_Axy23, complete genome	25235-25266	10	0.688
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_010311	Streptomyces sp. HK1 plasmid pSHK1, complete sequence	157156-157188	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	481368-481400	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	74839-74871	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP029339	Streptomyces sp. SM17 plasmid pSM17A, complete sequence	25274-25306	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	479011-479043	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1145920-1145952	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	365854-365886	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	450104-450136	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1267804-1267836	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	528650-528682	10	0.697
NZ_CP014859_6	6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT	1281352-1281384	33	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	630392-630424	10	0.697
NZ_CP014859_10	10.3|3825020|33|NZ_CP014859|PILER-CR,CRISPRCasFinder	3825020-3825052	33	MH271318	Gordonia phage Trine, complete genome	7210-7242	10	0.697
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP021026	Rhizobium sp. TAL182 plasmid pRetTAL182b, complete sequence	235905-235936	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013597	Rhizobium sp. N741 plasmid pRspN741b, complete sequence	269983-270014	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013501	Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence	270349-270380	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013507	Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence	269983-270014	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013518	Rhizobium sp. N113 plasmid pRspN113a, complete sequence	270349-270380	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013491	Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence	270352-270383	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013513	Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence	291236-291267	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013496	Rhizobium sp. N621 plasmid pRspN621a, complete sequence	270352-270383	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013591	Rhizobium sp. N871 plasmid pRspN871a, complete sequence	270352-270383	10	0.688
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP013603	Rhizobium sp. N731 plasmid pRspN731b, complete sequence	291236-291267	10	0.688
NZ_CP014859_12	12.4|3928708|35|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	3928708-3928742	35	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	71811-71845	10	0.714
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	467103-467134	10	0.688
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	498171-498202	10	0.688
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	440889-440920	10	0.688
NZ_CP014859_16	16.5|5411718|33|NZ_CP014859|CRISPRCasFinder,CRT	5411718-5411750	33	MN693761	Marine virus AFVG_250M219, complete genome	46173-46205	10	0.697
NZ_CP014859_17	17.1|5551084|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551084-5551116	33	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	210162-210194	10	0.697
NZ_CP014859_17	17.3|5551206|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551206-5551238	33	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1010594-1010626	10	0.697
NZ_CP014859_17	17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551267-5551299	33	NZ_CP022660	Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence	63429-63461	10	0.697
NZ_CP014859_17	17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551267-5551299	33	NZ_CP045061	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence	63433-63465	10	0.697
NZ_CP014859_17	17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551267-5551299	33	NZ_CP045054	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence	63440-63472	10	0.697
NZ_CP014859_17	17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551267-5551299	33	NZ_CP045058	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence	63439-63471	10	0.697
NZ_CP014859_17	17.6|5551389|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT	5551389-5551421	33	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	596799-596831	10	0.697
NZ_CP014859_5	5.2|1279849|34|NZ_CP014859|CRISPRCasFinder	1279849-1279882	34	NZ_CP035502	Sphingosinicella sp. BN140058 plasmid p1, complete sequence	230497-230530	11	0.676
NZ_CP014859_6	6.5|1281474|34|NZ_CP014859|CRISPRCasFinder,CRT	1281474-1281507	34	AB854109	Ralstonia phage RSB3 DNA, complete genome	19529-19562	11	0.676
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP006991	Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence	699511-699542	11	0.656
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	NZ_CP021128	Rhizobium sp. Kim5 plasmid pRetKim5d, complete sequence	640020-640051	11	0.656
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	CP007645	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803d, complete sequence	698432-698463	11	0.656
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	KY969628	Mycobacterium phage Zenon, complete genome	31891-31922	11	0.656
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	MH001447	Mycobacterium phage Nilo, complete genome	31886-31917	11	0.656
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	MH926059	Mycobacterium phage Riparian, complete genome	31347-31378	11	0.656
NZ_CP014859_11	11.2|3877264|32|NZ_CP014859|PILER-CR,CRT	3877264-3877295	32	KT591076	Mycobacterium phage Weiss13, complete genome	31579-31610	11	0.656
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP021026	Rhizobium sp. TAL182 plasmid pRetTAL182b, complete sequence	235904-235936	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013597	Rhizobium sp. N741 plasmid pRspN741b, complete sequence	269982-270014	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013501	Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence	270348-270380	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013507	Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence	269982-270014	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013518	Rhizobium sp. N113 plasmid pRspN113a, complete sequence	270348-270380	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013491	Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence	270351-270383	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013513	Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence	291235-291267	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013496	Rhizobium sp. N621 plasmid pRspN621a, complete sequence	270351-270383	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013591	Rhizobium sp. N871 plasmid pRspN871a, complete sequence	270351-270383	11	0.667
NZ_CP014859_11	11.5|3877263|33|NZ_CP014859|CRISPRCasFinder	3877263-3877295	33	NZ_CP013603	Rhizobium sp. N731 plasmid pRspN731b, complete sequence	291235-291267	11	0.667
NZ_CP014859_14	14.1|4628753|33|NZ_CP014859|CRISPRCasFinder	4628753-4628785	33	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2703139-2703171	11	0.667
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	83111-83142	11	0.656
NZ_CP014859_14	14.2|4628814|32|NZ_CP014859|CRISPRCasFinder	4628814-4628845	32	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	27568-27599	11	0.656

1. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK359354 (Mycobacterium phage PinkPlastic, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

2. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH576959 (Mycobacterium phage Pita2, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

3. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK112532 (Mycobacterium phage Bones, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

4. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MG925344 (Mycobacterium phage Ichabod, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

5. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MT889384 (Mycobacterium phage STLscum, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

6. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK359299 (Mycobacterium phage Petp2012, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

7. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MG920060 (Mycobacterium phage Bob3, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

8. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to AY500152 (Mycobacteriophage U2, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

9. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to EU744251 (Mycobacterium phage Jasper, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

10. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MG925351 (Mycobacterium phage MPlant7149, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

11. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK820638 (Mycobacterium phage HermioneGrange, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

12. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to AY500153 (Mycobacteriophage Bethlehem, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

13. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH590595 (Mycobacterium phage NEHalo, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

14. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK359304 (Mycobacterium phage SpikeBT, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

15. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK305893 (Mycobacterium phage Beatrix, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

16. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to KT438500 (Mycobacterium phage Pari, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

17. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to KJ690250 (Mycobacterium phage Pinto, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

18. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_023862 (Mycobacterium phage Alsfro, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

19. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to JN398369 (Mycobacterium phage RidgeCB, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

20. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_009877 (Mycobacterium phage U2, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

21. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MN813700 (Mycobacterium phage Atkinbua, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

22. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to EU744249 (Mycobacterium phage Lockley, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

23. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to KF560331 (Mycobacterium phage Graduation, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

24. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MT639654 (Mycobacterium phage Jerm2, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

25. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to JN660814 (Mycobacterium phage Dreamboat, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

26. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_031067 (Mycobacterium phage Makemake, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

27. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH669011 (Mycobacterium phage PherrisBueller, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

28. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH576971 (Mycobacterium phage Arlo, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

29. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK359300 (Mycobacterium phage AFIS, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

30. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH450113 (Mycobacterium phage BigMau, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

31. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH020236 (Mycobacterium phage GageAP, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

32. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_042327 (Mycobacterium virus BBPiebs31, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

33. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MN444869 (Mycobacterium phage DreamCatcher, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

34. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to EU744252 (Mycobacterium phage DD5, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

35. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH020244 (Mycobacterium phage Lopton, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

36. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to KT259047 (Mycobacterium phage Rufus, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

37. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK359316 (Mycobacterium phage Cueylyss, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

38. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_009878 (Mycobacterium phage Bethlehem, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

39. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MH450130 (Mycobacterium phage Rohr, complete genome) position: , mismatch: 5, identity: 0.844

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
 *** .****************.*******. *

40. spacer 8.1|1316469|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011453 (Altererythrobacter atlanticus strain 26DY36 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.848

cccggcggcggtgatcctgcggtgcaacgcgaa-	CRISPR spacer
cccggcggcggtgatgctgccgtg-atcgcgtat	Protospacer
*************** **** *** * **** * 

41. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NZ_CP009572 (Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence) position: , mismatch: 5, identity: 0.828

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
gcagcaacctgccgatcgtcgccttcgcg	Protospacer
******* *.**************.*. *

42. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 5, identity: 0.828

gcagc--aagccgccgatcgtcgcctccagg	CRISPR spacer
--agccgaaacggccgatcgtcgcctccagc	Protospacer
  ***  **.* ****************** 

43. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MH719191 (Pseudomonas phage Fc22, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

44. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MH719194 (Pseudomonas phage Ps60, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

45. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_006548 (Pseudomonas phage B3, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

46. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MK511059 (Pseudomonas phage CF78, partial genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

47. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MK511062 (Pseudomonas phage CF127, partial genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

48. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to AF232233 (Bacteriophage B3, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

49. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MK511061 (Pseudomonas phage CF125, partial genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

50. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_027992 (Pseudomonas phage JBD25, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

51. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to LN898172 (Pseudomonas phage vB_PaeS_PM105) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

52. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MK511063 (Pseudomonas phage CF177, partial genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

53. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MH719192 (Pseudomonas phage Ps56, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

54. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MN536027 (Pseudomonas phage vB_Pae-SS2019XII, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

55. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to KM389239 (UNVERIFIED: Pseudomonas phage F_HA1208sp/Pa1651 clone contig00003 genomic sequence) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

56. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MK934841 (Pseudomonas phage UMP151, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

57. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MH719193 (Pseudomonas phage H72, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

58. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to JX495041 (Pseudomonas phage JBD18, complete genome) position: , mismatch: 5, identity: 0.844

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
acgctgacgtcggcaagttcgagatgaagcgc	Protospacer
** *..*********** **** *********

59. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to KX855962 (Arthrobacter phage HumptyDumpty, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

60. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MF185721 (Arthrobacter phage Kabreeze, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

61. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to KX522650 (Arthrobacter Phage Conboy, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

62. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MN204503 (Arthrobacter phage Linus, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

63. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MF185723 (Arthrobacter phage RosiePosie, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

64. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to KX670787 (Arthrobacter phage Chocolat, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

65. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MF668274 (Arthrobacter phage JayCookie, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

66. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MK494107 (Arthrobacter phage Chipper1996, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

67. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MF185724 (Arthrobacter phage Scavito, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

68. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to KX670786 (Arthrobacter phage Chubster, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

69. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MN204499 (Arthrobacter phage Mordred, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

70. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to MF185725 (Arthrobacter phage Tophat, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

71. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to KU160660 (Arthrobacter phage PrincessTrina, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

72. spacer 4.10|1200723|34|NZ_CP014859|CRISPRCasFinder matches to KX855961 (Arthrobacter phage EdgarPoe, complete genome) position: , mismatch: 6, identity: 0.824

ccgacgaggt-cttggctacgccgttggcggcacg	CRISPR spacer
-cggcggcgtgcttggctacgccggcggcggcacg	Protospacer
 **.**. ** ************* .*********

73. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_LR134460 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 18, complete sequence) position: , mismatch: 6, identity: 0.812

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gaatccgtcgaggggatcaccgcgttcctgca	Protospacer
* * ***.**************** ***  **

74. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MN369760 (Mycobacterium phage KyMonks1A, complete genome) position: , mismatch: 6, identity: 0.812

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
 *** .****** *********.*******. *

75. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK112540 (Mycobacterium phage Froghopper, complete genome) position: , mismatch: 6, identity: 0.812

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
 *** .****** *********.*******. *

76. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_042326 (Mycobacterium virus KSSJEB, complete genome) position: , mismatch: 6, identity: 0.812

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
 *** .****** *********.*******. *

77. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_028941 (Mycobacterium phage Turj99, complete genome) position: , mismatch: 6, identity: 0.812

-gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
 *** .****** *********.*******. *

78. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK359354 (Mycobacterium phage PinkPlastic, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

79. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH576959 (Mycobacterium phage Pita2, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

80. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK112532 (Mycobacterium phage Bones, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

81. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MG925344 (Mycobacterium phage Ichabod, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

82. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MT889384 (Mycobacterium phage STLscum, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

83. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK359299 (Mycobacterium phage Petp2012, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

84. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MG920060 (Mycobacterium phage Bob3, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

85. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to AY500152 (Mycobacteriophage U2, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

86. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to EU744251 (Mycobacterium phage Jasper, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

87. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MG925351 (Mycobacterium phage MPlant7149, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

88. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK820638 (Mycobacterium phage HermioneGrange, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

89. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to AY500153 (Mycobacteriophage Bethlehem, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

90. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH590595 (Mycobacterium phage NEHalo, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

91. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK359304 (Mycobacterium phage SpikeBT, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

92. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK305893 (Mycobacterium phage Beatrix, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

93. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to KT438500 (Mycobacterium phage Pari, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

94. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to KJ690250 (Mycobacterium phage Pinto, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

95. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_023862 (Mycobacterium phage Alsfro, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

96. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to JN398369 (Mycobacterium phage RidgeCB, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

97. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_009877 (Mycobacterium phage U2, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

98. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MN813700 (Mycobacterium phage Atkinbua, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

99. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to EU744249 (Mycobacterium phage Lockley, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

100. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to KF560331 (Mycobacterium phage Graduation, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

101. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MT639654 (Mycobacterium phage Jerm2, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

102. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to JN660814 (Mycobacterium phage Dreamboat, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

103. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_031067 (Mycobacterium phage Makemake, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

104. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH669011 (Mycobacterium phage PherrisBueller, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

105. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH576971 (Mycobacterium phage Arlo, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

106. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK359300 (Mycobacterium phage AFIS, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

107. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH450113 (Mycobacterium phage BigMau, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

108. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH020236 (Mycobacterium phage GageAP, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

109. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_042327 (Mycobacterium virus BBPiebs31, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

110. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MN444869 (Mycobacterium phage DreamCatcher, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

111. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to EU744252 (Mycobacterium phage DD5, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

112. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH020244 (Mycobacterium phage Lopton, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

113. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to KT259047 (Mycobacterium phage Rufus, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

114. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK359316 (Mycobacterium phage Cueylyss, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

115. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_009878 (Mycobacterium phage Bethlehem, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

116. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MH450130 (Mycobacterium phage Rohr, complete genome) position: , mismatch: 6, identity: 0.818

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgaggggatcaccacgatccgcaa	Protospacer
  *** .****************.*******. *

117. spacer 7.2|1312532|31|NZ_CP014859|PILER-CR matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 6, identity: 0.806

gccccttgacggtcaggtaccacgccgacgg	CRISPR spacer
tcgccttgatggtcaggtaccacggcgacat	Protospacer
 * ******.************** ****. 

118. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 6, identity: 0.793

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
tcgccatggcgccgatcgtcgcctccagc	Protospacer
 *. ** * ******************* 

119. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.793

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
ccaacaagccgccgatcgtcccctaccgc	Protospacer
 **.**************** *** * * 

120. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 6, identity: 0.793

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
ccaacaagccgccgatcgtcccctaccgc	Protospacer
 **.**************** *** * * 

121. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 6, identity: 0.793

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
gcgtgaagccgccggtcatcgcctccagc	Protospacer
**.  *********.**.********** 

122. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to CP047390 (Agrobacterium sp. CGMCC 11546 plasmid pB) position: , mismatch: 6, identity: 0.818

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
tcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
**   *.********************.** **

123. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP033036 (Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence) position: , mismatch: 6, identity: 0.818

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
tcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
**   *.********************.** **

124. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_003064 (Agrobacterium fabrum str. C58 plasmid At, complete sequence) position: , mismatch: 6, identity: 0.818

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
tcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
**   *.********************.** **

125. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP033024 (Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence) position: , mismatch: 6, identity: 0.818

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
tcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
**   *.********************.** **

126. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to HQ332141 (Halorubrum phage CGphi46 genomic sequence) position: , mismatch: 6, identity: 0.812

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
ccgcgaacgtcggcatggtcgacatgacgctc	Protospacer
 * * ********** *********** ** *

127. spacer 16.8|5411536|32|NZ_CP014859|PILER-CR matches to NZ_CP016080 (Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence) position: , mismatch: 6, identity: 0.812

gtaagcgcttccgtgtagttgtcgacgtgcgc-	CRISPR spacer
acaagcgctcccgtgtagatgtcgaag-gcgcg	Protospacer
..*******.******** ****** * **** 

128. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MK977702 (Gordonia terrae phage McKinley, complete genome) position: , mismatch: 7, identity: 0.806

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgcca	Protospacer
 * * **  ******** ***** ************

129. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MK977702 (Gordonia terrae phage McKinley, complete genome) position: , mismatch: 7, identity: 0.806

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgcca	Protospacer
 * * **  ******** ***** ************

130. spacer 5.2|1279849|34|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013856 (Pseudonocardia sp. HH130630-07 plasmid pLS2-2, complete sequence) position: , mismatch: 7, identity: 0.794

cacaacgacgtctacggcgacggcgagtcgggca	CRISPR spacer
cgcaacgacggcgacggcgacggcgacggggtca	Protospacer
*.******** * *************   ** **

131. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MF324902 (Rhodococcus phage Krishelle, complete genome) position: , mismatch: 7, identity: 0.781

gcagccgccgaggggatcaccgc-gatccgtca	CRISPR spacer
gcagccgcagaggagatcaccgcagaggcagc-	Protospacer
******** ****.********* **  *. * 

132. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MF324903 (Rhodococcus phage AppleCloud, complete genome) position: , mismatch: 7, identity: 0.781

gcagccgccgaggggatcaccgc-gatccgtca	CRISPR spacer
gcagccgcagaggagatcaccgcagaggcagc-	Protospacer
******** ****.********* **  *. * 

133. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_LR134460 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 18, complete sequence) position: , mismatch: 7, identity: 0.788

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
cgaatccgtcgaggggatcaccgcgttcctgca	Protospacer
 * * ***.**************** ***  **

134. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MN369760 (Mycobacterium phage KyMonks1A, complete genome) position: , mismatch: 7, identity: 0.788

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
  *** .****** *********.*******. *

135. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MK112540 (Mycobacterium phage Froghopper, complete genome) position: , mismatch: 7, identity: 0.788

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
  *** .****** *********.*******. *

136. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_042326 (Mycobacterium virus KSSJEB, complete genome) position: , mismatch: 7, identity: 0.788

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
  *** .****** *********.*******. *

137. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_028941 (Mycobacterium phage Turj99, complete genome) position: , mismatch: 7, identity: 0.788

-ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctgca-tcgccgatgggatcaccacgatccgcaa	Protospacer
  *** .****** *********.*******. *

138. spacer 7.2|1312532|31|NZ_CP014859|PILER-CR matches to MN284893 (Mycobacterium phage LilMcDreamy, complete genome) position: , mismatch: 7, identity: 0.774

gccccttgacggtcaggtaccacgccgacgg	CRISPR spacer
ggcttgagacggtcatgtacgacgccgacgg	Protospacer
* *..  ******** **** **********

139. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 7, identity: 0.759

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
gcagcaagcggccgatcgtctccgtgccg	Protospacer
********* ********** ** .   *

140. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP030828 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence) position: , mismatch: 7, identity: 0.788

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
tgagcgcctcttcctggtcatgggtgacgaaga	Protospacer
*    *.********************.** **

141. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.788

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
ccagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.*   *.********************.** **

142. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP016500 (Agrobacterium sp. RAC06 plasmid pBSY240_1, complete sequence) position: , mismatch: 7, identity: 0.788

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
ccatggcctcttcctggtcatgggtgacataga	Protospacer
.* ***.********************..  **

143. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP045856 (Agrobacterium sp. MA01 plasmid punanmed2, complete sequence) position: , mismatch: 7, identity: 0.788

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
ccatggcctcttcctggtcatgggtgacataga	Protospacer
.* ***.********************..  **

144. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_015184 (Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence) position: , mismatch: 7, identity: 0.788

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
tctgcgcctcttcctgatcatgggtgacgatca	Protospacer
**.  *.*********.**********.*** *

145. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP015091 (Pelagibaca abyssi strain JLT2014 plasmid pPABY1, complete sequence) position: , mismatch: 7, identity: 0.781

atcg-ccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
-tcgcccgcgtcgcggatcgcctctaacccaag	Protospacer
 *** ******* ***********.****. . 

146. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to MT889367 (Gordonia phage Orla, complete genome) position: , mismatch: 7, identity: 0.781

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcccagatcgcctcgcactcagc	Protospacer
****.********.*********  **.. **

147. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP015091 (Pelagibaca abyssi strain JLT2014 plasmid pPABY1, complete sequence) position: , mismatch: 7, identity: 0.788

gatcg-ccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
-atcgcccgcgtcgcggatcgcctctaacccaag	Protospacer
 **** ******* ***********.****. . 

148. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to MT889367 (Gordonia phage Orla, complete genome) position: , mismatch: 7, identity: 0.788

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gatcgtcgcgtcccagatcgcctcgcactcagc	Protospacer
*****.********.*********  **.. **

149. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013635 (Rhizobium sp. N324 plasmid pRspN324e, complete sequence) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
taggcatcgtcggcaaggtcgacatgcagcga	Protospacer
    ** ******************* **** 

150. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_LR536451 (Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 2) position: , mismatch: 7, identity: 0.781

actccaa----cgtcggcaaggtcgacatgaagcgc	CRISPR spacer
----caggcctcgtcggcaagatcgacatggagcgc	Protospacer
    **.    **********.********.*****

151. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP015203 (Rhodococcus sp. 008 plasmid pR8L1, complete sequence) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agacctcagtcggcaagttcgacaagaagcgc	Protospacer
*  **   ********* ****** *******

152. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP044283 (Rhodococcus erythropolis strain X5 plasmid pRhX5, complete sequence) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agacctcagtcggcaagttcgacaagaagcgc	Protospacer
*  **   ********* ****** *******

153. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP011297 (Rhodococcus erythropolis strain BG43 plasmid pRLLBG43, complete sequence) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agacctcagtcggcaagttcgacaagaagcgc	Protospacer
*  **   ********* ****** *******

154. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP014942 (Rhodococcus sp. BH4 plasmid, complete sequence) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agacctcagtcggcaagttcgacaagaagcgc	Protospacer
*  **   ********* ****** *******

155. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP017300 (Rhodococcus sp. YL-1 plasmid pYLC1, complete sequence) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agacctcagtcggcaagttcgacaagaagcgc	Protospacer
*  **   ********* ****** *******

156. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agacctcggtcggcaagttcgacaagaagcgc	Protospacer
*  **   ********* ****** *******

157. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to KY555147 (Caulobacter phage Ccr34, complete genome) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
ccgtcaacgtcggcaagatcgccatgaacggc	Protospacer
 * .*************.*** ******  **

158. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_019410 (Caulobacter phage CcrKarma, complete genome) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
ccgtcaacgtcggcaagatcgccatgaacggc	Protospacer
 * .*************.*** ******  **

159. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to KY555146 (Caulobacter phage Ccr32, complete genome) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
ccgtcaacgtcggcaagatcgccatgaacggc	Protospacer
 * .*************.*** ******  **

160. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_019407 (Caulobacter phage CcrMagneto, complete genome) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
ccgtcaacgtcggcaagatcgccatgaacggc	Protospacer
 * .*************.*** ******  **

161. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to JX163858 (Caulobacter phage phiCbK, complete genome) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
ccgtcaacgtcggcaagatcgccatgaacggc	Protospacer
 * .*************.*** ******  **

162. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_019411 (Caulobacter phage CcrSwift, complete genome) position: , mismatch: 7, identity: 0.781

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
ccgtcaacgtcggcaagatcgccatgaacggc	Protospacer
 * .*************.*** ******  **

163. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 7, identity: 0.781

--actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tgatccc--catcggcaagggcgacatcaagcgc	Protospacer
  *..**  *.********* ****** ******

164. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MK977702 (Gordonia terrae phage McKinley, complete genome) position: , mismatch: 8, identity: 0.784

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgcca	Protospacer
  * * **  ******** ***** ************

165. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.784

tgttcg-cgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
-gctggccgcgcccgcacctgcacctgcacccgaggcc	Protospacer
 *.* * ****.*************.******* * * 

166. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MK977702 (Gordonia terrae phage McKinley, complete genome) position: , mismatch: 8, identity: 0.784

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgcca	Protospacer
  * * **  ******** ***** ************

167. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.784

tgttcg-cgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
-gctggccgcgcccgcacctgcacctgcacccgaggcc	Protospacer
 *.* * ****.*************.******* * * 

168. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gagccagcacccgcacccgcacccgcacccgcacca	Protospacer
*  *  **..*******.**************.***

169. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MK937601 (Gordonia phage Charming, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

170. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH976519 (Gordonia phage Tangent, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

171. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH976510 (Gordonia phage Fosterous, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

172. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH976518 (Gordonia phage Stultus, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

173. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH479924 (Gordonia phage Rofo, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

174. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MK937594 (Gordonia phage Galadriel, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

175. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MN329673 (Gordonia phage Jabberwocky, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

176. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH651166 (Gordonia phage Angelicage, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

177. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MT639640 (Gordonia phage Paries, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

178. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to NC_042108 (Gordonia phage Brandonk123, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

179. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH976514 (Gordonia phage Nordenberg, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

180. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH976507 (Gordonia phage Ailee, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

181. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MT498035 (Gordonia Phage Barsten, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

182. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to NC_031239 (Gordonia phage Vivi2, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

183. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gagccagcacccgcacccgcacccgcacccgcacca	Protospacer
*  *  **..*******.**************.***

184. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MK937601 (Gordonia phage Charming, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

185. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH976519 (Gordonia phage Tangent, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

186. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH976510 (Gordonia phage Fosterous, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

187. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH976518 (Gordonia phage Stultus, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

188. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH479924 (Gordonia phage Rofo, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

189. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MK937594 (Gordonia phage Galadriel, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

190. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MN329673 (Gordonia phage Jabberwocky, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

191. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH651166 (Gordonia phage Angelicage, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

192. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MT639640 (Gordonia phage Paries, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

193. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to NC_042108 (Gordonia phage Brandonk123, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

194. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH976514 (Gordonia phage Nordenberg, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

195. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH976507 (Gordonia phage Ailee, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

196. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MT498035 (Gordonia Phage Barsten, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

197. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to NC_031239 (Gordonia phage Vivi2, complete genome) position: , mismatch: 8, identity: 0.778

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
 * * **  ******** ***** ***********.

198. spacer 5.2|1279849|34|NZ_CP014859|CRISPRCasFinder matches to NZ_CP032827 (Sphingomonas sp. YZ-8 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

cacaacgacgtctacggcgacggcgagtcgggca-	CRISPR spacer
ggcaacgacttctgcggcgacggcga-tctgatat	Protospacer
 .******* ***.************ ** *..* 

199. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 8, identity: 0.75

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tttgccgccgaggggaccaccgcgatgcgctg	Protospacer
 . *************.********* **...

200. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP020911 (Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence) position: , mismatch: 8, identity: 0.75

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tcagccgccggggtgatcaccgcgatctcctc	Protospacer
 *********.** *************. .. 

201. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tttgccgccgaggggaccaccgcgatgcgctg	Protospacer
 . *************.********* **...

202. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 8, identity: 0.75

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
tcagccgccggggtgatcaccgcgatctcctc	Protospacer
 *********.** *************. .. 

203. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP016354 (Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence) position: , mismatch: 8, identity: 0.75

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctcaccgccgaggagatcaccgcgatcctgcg	Protospacer
 . .*********.**************  *.

204. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgaggggatccgcgcgacggccta	Protospacer
******************  *****.   ..*

205. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgaggggatccgcgcgacggccta	Protospacer
*******************  *****.   ..*

206. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP020911 (Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence) position: , mismatch: 8, identity: 0.758

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gtcagccgccggggtgatcaccgcgatctcctc	Protospacer
* *********.** *************. .. 

207. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 8, identity: 0.758

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gtcagccgccggggtgatcaccgcgatctcctc	Protospacer
* *********.** *************. .. 

208. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP016354 (Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence) position: , mismatch: 8, identity: 0.758

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gctcaccgccgaggagatcaccgcgatcctgcg	Protospacer
* . .*********.**************  *.

209. spacer 7.1|1312471|31|NZ_CP014859|PILER-CR matches to NZ_CP047657 (Paraglaciecola mesophila strain GPM4 plasmid unnamed) position: , mismatch: 8, identity: 0.742

tgtgtgcttcacgctgccacctctacgataa	CRISPR spacer
tgagtgcttcatgctgccacctcacccgttg	Protospacer
** ********.***********  * .* .

210. spacer 7.4|1312531|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 8, identity: 0.758

tgccccttgacggtcaggtaccacgccgacggg	CRISPR spacer
ctcgccttgatggtcaggtaccacggcgacatt	Protospacer
. * ******.************** ****.  

211. spacer 7.4|1312531|33|NZ_CP014859|CRISPRCasFinder matches to MN284893 (Mycobacterium phage LilMcDreamy, complete genome) position: , mismatch: 8, identity: 0.758

tgccccttgacggtcaggtaccacgccgacggg	CRISPR spacer
tggcttgagacggtcatgtacgacgccgacggc	Protospacer
** *..  ******** **** ********** 

212. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.724

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
tcagccagccgccgatcgtcgcaggtgag	Protospacer
 **** ****************   ...*

213. spacer 8.3|1316591|29|NZ_CP014859|CRT matches to NC_008697 (Nocardioides sp. JS614 plasmid pNOCA01, complete sequence) position: , mismatch: 8, identity: 0.724

gcagcaagccgccgatcgtcgcctccagg	CRISPR spacer
cggtcaagccgctgatcgtcgcctcgacc	Protospacer
  . ********.************ *  

214. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

215. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

216. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

217. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_015597 (Sinorhizobium meliloti AK83 plasmid pSINME01, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

218. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

219. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

220. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

221. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

222. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

223. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

224. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP019483 (Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

225. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

226. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

227. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

228. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

229. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

230. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

231. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

232. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
cgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
.    *.********************.** **

233. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_018022 (Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
acagcgcctcttcctggtcgtgggtgacgatca	Protospacer
 *   *.************.*******.*** *

234. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
acagcgcctcttcctggtcgtgggtgacgatca	Protospacer
 *   *.************.*******.*** *

235. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NC_008703 (Mycobacterium sp. KMS plasmid pMKMS01, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
acaacgcctcttcctggtcgtgggtgacgatca	Protospacer
 *   *.************.*******.*** *

236. spacer 10.4|3825081|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

tcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
ccatggcctcttgctggtcatgggtgaccaaca	Protospacer
.* ***.***** **************. *  *

237. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.784

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctccagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..*   *.********************.** **

238. spacer 11.1|3877203|32|NZ_CP014859|PILER-CR,CRT matches to MT639639 (Gordonia phage LittleFella, complete genome) position: , mismatch: 8, identity: 0.75

tgacacccccggttaccgccgggggtgtcgtt	CRISPR spacer
gttcgcccccggttagcgccgggggcgttctt	Protospacer
   *.********** *********.**. **

239. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 8, identity: 0.75

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
ggcaccgcgtcctggatcgcctacaacgaggc	Protospacer
. *.********.********* ****   **

240. spacer 13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015369 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p2, complete sequence) position: , mismatch: 8, identity: 0.758

gggtcgtcggtggccttcccggcgcgctctgcc	CRISPR spacer
gcctggacgatggccttcccggcgcgcactggg	Protospacer
*  * * **.***************** ***  

241. spacer 13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_JX627582 (Methylobacterium oryzae CBMB20 plasmid pMOC3, complete sequence) position: , mismatch: 8, identity: 0.758

gggtcgtcggtggccttcccggcgcgctctgcc	CRISPR spacer
gcctggacgatggccttcccggcgcgcactggg	Protospacer
*  * * **.***************** ***  

242. spacer 13.4|4574509|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047145 (Streptomyces sp. HF10 plasmid plas1, complete sequence) position: , mismatch: 8, identity: 0.758

gacgcctcgatcgacagctgaccgaccaccccc	CRISPR spacer
aagcccgtcatcgaccgctgaccgaccaccacc	Protospacer
.*  ** . ****** ************** **

243. spacer 13.7|4574692|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049032 (Fluviibacterium aquatile strain SC52 plasmid pSC52_4, complete sequence) position: , mismatch: 8, identity: 0.758

caggccagcgacgactccgcgttcgacagccgc	CRISPR spacer
taggccagtgacgactccgctttcgcacgccca	Protospacer
.*******.*********** ****   ***  

244. spacer 13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.758

---gttcccggaggtcccgtacacccacaccgagcc	CRISPR spacer
cgcattc---gatgtcctgtacacccacaccgaggg	Protospacer
   .***   ** ****.****************  

245. spacer 13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 8, identity: 0.758

---gttcccggaggtcccgtacacccacaccgagcc	CRISPR spacer
cgcattc---gatgtcctgtacacccacaccgaggg	Protospacer
   .***   ** ****.****************  

246. spacer 13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 8, identity: 0.758

---gttcccggaggtcccgtacacccacaccgagcc	CRISPR spacer
cgcattc---gatgtcctgtacacccacaccgaggg	Protospacer
   .***   ** ****.****************  

247. spacer 13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.758

---gttcccggaggtcccgtacacccacaccgagcc	CRISPR spacer
cgcattc---gatgtcctgtacacccacaccgaggg	Protospacer
   .***   ** ****.****************  

248. spacer 13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.758

---gttcccggaggtcccgtacacccacaccgagcc	CRISPR spacer
cgcattc---gatgtcctgtacacccacaccgaggg	Protospacer
   .***   ** ****.****************  

249. spacer 13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.758

---gttcccggaggtcccgtacacccacaccgagcc	CRISPR spacer
cgcattc---gatgtcctgtacacccacaccgaggg	Protospacer
   .***   ** ****.****************  

250. spacer 13.8|4574753|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.758

---gttcccggaggtcccgtacacccacaccgagcc	CRISPR spacer
cgcattc---gatgtcctgtacacccacaccgaggg	Protospacer
   .***   ** ****.****************  

251. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP050081 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence) position: , mismatch: 8, identity: 0.75

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tgcccaacgtcggcaaggtcgatgtgatcggc	Protospacer
  .*******************..***   **

252. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP050098 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence) position: , mismatch: 8, identity: 0.75

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tgcccaacgtcggcaaggtcgatgtgatcggc	Protospacer
  .*******************..***   **

253. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP049731 (Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence) position: , mismatch: 8, identity: 0.75

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tgcccaacgtcggcaaggtcgatgtgatcggc	Protospacer
  .*******************..***   **

254. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 8, identity: 0.75

actccaa----cgtcggcaaggtcgacatgaagcgc	CRISPR spacer
----taagcctcgtcggcaacgtcggcatgaagcga	Protospacer
    .**    ********* ****.********* 

255. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP053206 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence) position: , mismatch: 8, identity: 0.75

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tgcccaacgtcggcaaggtcgatgtgatcggc	Protospacer
  .*******************..***   **

256. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 8, identity: 0.75

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agatcgagatcggcaaggccgacatcaagcgc	Protospacer
*  .*.* .*********.****** ******

257. spacer 16.10|5411658|32|NZ_CP014859|PILER-CR matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 8, identity: 0.75

tgtgtgtggtcggtcaggccgcgagacgcagc	CRISPR spacer
tgggcagcttcggtcagggcgcgagacgcggc	Protospacer
** *..   ********* **********.**

258. spacer 16.10|5411658|32|NZ_CP014859|PILER-CR matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

tgtgtgtggtcggtcaggccgcgagacgcagc	CRISPR spacer
tgggcagcttcggtcagggcgcgagacgcggc	Protospacer
** *..   ********* **********.**

259. spacer 16.10|5411658|32|NZ_CP014859|PILER-CR matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

tgtgtgtggtcggtcaggccgcgagacgcagc	CRISPR spacer
tgggcagcttcggtcagggcgcgagacgcggc	Protospacer
** *..   ********* **********.**

260. spacer 16.10|5411658|32|NZ_CP014859|PILER-CR matches to NC_009621 (Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence) position: , mismatch: 8, identity: 0.75

tgtgtgtggtcggtcaggccgcgagacgcagc	CRISPR spacer
tgggcagcttcggtcagggcgcgagacgcggc	Protospacer
** *..   ********* **********.**

261. spacer 17.1|5551084|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to JQ680367 (Unidentified phage clone 2203_scaffold802 genomic sequence) position: , mismatch: 8, identity: 0.758

cgcccacgcgcccttcttcgtggggtcgacctg--	CRISPR spacer
agcccacgcgcccttgttggtggggc--gcttgtt	Protospacer
 ************** ** ******.  .*.**  

262. spacer 17.3|5551206|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.758

ccgggcagggggccgccggtgccccggcacggg	CRISPR spacer
tggggcaaggggccgccggtgccctggcgctat	Protospacer
. *****.****************.***.* . 

263. spacer 18.4|5553663|33|NZ_CP014859|PILER-CR,CRT matches to NZ_CP053208 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1B, complete sequence) position: , mismatch: 8, identity: 0.758

accgcagttgatgcactcgtcggcggattcgtc	CRISPR spacer
accgcagttgatgaactcgtccgcctatcgcgc	Protospacer
************* ******* **  **.   *

264. spacer 18.8|5553664|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP053208 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1B, complete sequence) position: , mismatch: 8, identity: 0.75

ccgcagttgatgcactcgtcggcggattcgtc	CRISPR spacer
ccgcagttgatgaactcgtccgcctatcgcgc	Protospacer
************ ******* **  **.   *

265. spacer 19.1|5776183|33|NZ_CP014859|PILER-CR matches to MH884510 (Exiguobacterium phage vB_EalM-137, complete genome) position: , mismatch: 8, identity: 0.758

catgtcggatgcggcggactcgatcgccagcct	CRISPR spacer
gacgaaggaagcggcggacttgatcgccagcaa	Protospacer
 *.*  *** **********.**********  

266. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to NZ_CP015744 (Shinella sp. HZN7 plasmid pShin-08, complete sequence) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gttcttcgccgatttgcaggaactgcatgg	Protospacer
************* *******.. * *   

267. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MG962374 (Mycobacterium phage Paola, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

268. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to KX585251 (Mycobacterium phage Waterfoul, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccaatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

269. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MH051255 (Mycobacterium phage Leston, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

270. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to KX636165 (Mycobacterium phage Gengar, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

271. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MF185720 (Mycobacterium phage Guillsminger, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

272. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to NC_024366 (Mycobacterium phage OkiRoe, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

273. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to NC_023724 (Mycobacterium phage Larva, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgca	Protospacer
*..  ****************** ** *. 

274. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MH651171 (Mycobacterium phage Collard, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

275. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MH576966 (Mycobacterium phage Thyatira, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccaatcgccgatgtgcaggagttggcgcg	Protospacer
*..  ****************** ** *. 

276. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MF185717 (Mycobacterium phage AlleyCat, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgca	Protospacer
*..  ****************** ** *. 

277. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MK376961 (Gordonia phage Asapag, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
tgttcgtgccgctgtgcaggagtgggcgtc	Protospacer
  *.. .**** ************** ***

278. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to NC_028947 (Mycobacterium phage Kratio, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgca	Protospacer
*..  ****************** ** *. 

279. spacer 19.2|5776247|30|NZ_CP014859|PILER-CR matches to MF185719 (Mycobacterium phage Edugator, complete genome) position: , mismatch: 8, identity: 0.733

gttcttcgccgatgtgcaggagtgggagtc	CRISPR spacer
gccgatcgccgatgtgcaggagttggcgca	Protospacer
*..  ****************** ** *. 

280. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
agagccagcacccgcacccgcacccgcacccgcacca	Protospacer
 *  *  **..*******.**************.***

281. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MK937601 (Gordonia phage Charming, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

282. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH976519 (Gordonia phage Tangent, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

283. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH976510 (Gordonia phage Fosterous, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

284. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH976518 (Gordonia phage Stultus, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

285. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH479924 (Gordonia phage Rofo, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

286. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MK937594 (Gordonia phage Galadriel, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

287. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MN329673 (Gordonia phage Jabberwocky, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

288. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH651166 (Gordonia phage Angelicage, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

289. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MT639640 (Gordonia phage Paries, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

290. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to NC_042108 (Gordonia phage Brandonk123, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

291. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH976514 (Gordonia phage Nordenberg, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

292. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH976507 (Gordonia phage Ailee, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

293. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MT498035 (Gordonia Phage Barsten, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

294. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to NC_031239 (Gordonia phage Vivi2, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

295. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
agagccagcacccgcacccgcacccgcacccgcacca	Protospacer
 *  *  **..*******.**************.***

296. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MK937601 (Gordonia phage Charming, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

297. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH976519 (Gordonia phage Tangent, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

298. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH976510 (Gordonia phage Fosterous, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

299. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH976518 (Gordonia phage Stultus, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

300. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH479924 (Gordonia phage Rofo, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

301. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MK937594 (Gordonia phage Galadriel, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

302. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MN329673 (Gordonia phage Jabberwocky, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

303. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH651166 (Gordonia phage Angelicage, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

304. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MT639640 (Gordonia phage Paries, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

305. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to NC_042108 (Gordonia phage Brandonk123, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

306. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH976514 (Gordonia phage Nordenberg, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

307. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH976507 (Gordonia phage Ailee, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

308. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MT498035 (Gordonia Phage Barsten, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

309. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to NC_031239 (Gordonia phage Vivi2, complete genome) position: , mismatch: 9, identity: 0.757

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgcccggttccgcaccggcaccggcacccgcgccg	Protospacer
  * * **  ******** ***** ***********.

310. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.75

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctggccgcgcccgcacctgcacctgcacccgaggcc	Protospacer
 *   ****.*************.******* * * 

311. spacer 4.11|1200795|36|NZ_CP014859|CRISPRCasFinder matches to MH976512 (Gordonia phage Geodirt, complete genome) position: , mismatch: 9, identity: 0.75

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgccaggttccgcaccggcaccggcacccgcgccg	Protospacer
 * *  *  ******** ***** ***********.

312. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.75

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctggccgcgcccgcacctgcacctgcacccgaggcc	Protospacer
 *   ****.*************.******* * * 

313. spacer 4.13|1200943|36|NZ_CP014859|CRISPRCasFinder matches to MH976512 (Gordonia phage Geodirt, complete genome) position: , mismatch: 9, identity: 0.75

gttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
ctgccaggttccgcaccggcaccggcacccgcgccg	Protospacer
 * *  *  ******** ***** ***********.

314. spacer 5.2|1279849|34|NZ_CP014859|CRISPRCasFinder matches to NZ_CP032326 (Azospirillum brasilense strain MTCC4035 plasmid p5, complete sequence) position: , mismatch: 9, identity: 0.735

cacaacgacgtctacggcgacggcgagtcgggca	CRISPR spacer
ttcaacggcgtctaccgcgacggcgagggcgccg	Protospacer
. *****.******* ***********   * *.

315. spacer 5.2|1279849|34|NZ_CP014859|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.735

cacaacgacgtctacggcgacggcgagtcgggca	CRISPR spacer
cgcgacgacgtcgacggcgactgcgagtggctgg	Protospacer
*.*.******** ******** ****** *   .

316. spacer 5.2|1279849|34|NZ_CP014859|CRISPRCasFinder matches to MT889392 (Microbacterium phage Lahqtemish, complete genome) position: , mismatch: 9, identity: 0.735

cacaacgacgtctacggcgacggcgagtcgggca	CRISPR spacer
ttcatgattgtctacggcggcggcgcgtcgggca	Protospacer
. **  . .**********.***** ********

317. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

318. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

319. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

320. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

321. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

322. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

323. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

324. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

325. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

326. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

327. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

328. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

329. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgcgggtgccga	Protospacer
********** *.***********. .  . *

330. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021332 (Maritalea myrionectae strain HL2708#5 plasmid pHL2708Y3, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ttggcagccgaggggatcaccacgatttgcta	Protospacer
 ..** ***************.****..*..*

331. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 9, identity: 0.719

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ttcccggccgaggtgatcaccgagatccgcaa	Protospacer
 .  * ******* ******** ******. *

332. spacer 6.2|1281414|32|NZ_CP014859|PILER-CR matches to NZ_CP034431 (Bradyrhizobium sp. LCT2 plasmid pLCT2, complete sequence) position: , mismatch: 9, identity: 0.719

gatgccgagaaggccaatgatca-----agagtggtg	CRISPR spacer
gatgccgagcaagccaatgatcatttcgacgg-----	Protospacer
********* *.***********     * .*     

333. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctttgccgccgaggggaccaccgcgatgcgctg	Protospacer
  . *************.********* **...

334. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ctttgccgccgaggggaccaccgcgatgcgctg	Protospacer
  . *************.********* **...

335. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

336. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

337. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

338. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

339. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

340. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

341. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

342. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

343. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

344. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

345. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

346. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

347. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.727

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgcgggtgccga	Protospacer
*********** *.***********. .  . *

348. spacer 7.1|1312471|31|NZ_CP014859|PILER-CR matches to NZ_CP029540 (Aquitalea sp. USM4 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tgtgtgcttcacgctgccacctctacgataa	CRISPR spacer
gccgtgcttcacgccgccacctttaccagtc	Protospacer
  .***********.*******.*** *   

349. spacer 8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 9, identity: 0.727

tgcttccgctcggtcgggctcgaccatcacgcc	CRISPR spacer
cagagccagtcgctcgcgctcgaccatcacgcc	Protospacer
..   **. *** *** ****************

350. spacer 8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

tgcttccgctcggtcgggctcgaccatcacgcc	CRISPR spacer
cagagccagtcgctcgcgctcgaccatcacgcc	Protospacer
..   **. *** *** ****************

351. spacer 8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 9, identity: 0.727

tgcttccgctcggtcgggctcgaccatcacgcc	CRISPR spacer
cagagccagtcgctcgcgctcgaccatcacgcc	Protospacer
..   **. *** *** ****************

352. spacer 8.2|1316530|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

tgcttccgctcggtcgggctcgaccatcacgcc	CRISPR spacer
cagagccagtcgctcgcgctcgaccatcacgcc	Protospacer
..   **. *** *** ****************

353. spacer 10.3|3825020|33|NZ_CP014859|PILER-CR,CRISPRCasFinder matches to MN234219 (Mycobacterium phage Mercurio, complete genome) position: , mismatch: 9, identity: 0.727

ttacaccagcgcgggcgggaactccggggcgtt	CRISPR spacer
cttcaccagcgcgcgccggaactccggtactcc	Protospacer
.* ********** ** ********** .* ..

354. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

355. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

356. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to CP047390 (Agrobacterium sp. CGMCC 11546 plasmid pB) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
atggtcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
*   **   *.********************.** **

357. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

358. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NC_015597 (Sinorhizobium meliloti AK83 plasmid pSINME01, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

359. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

360. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

361. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

362. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

363. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

364. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

365. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP030828 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence) position: , mismatch: 9, identity: 0.757

------agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
atggtgagc------gcctcttcctggtcatgggtgacgaaga	Protospacer
      ***      *.********************.** **

366. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP019483 (Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

367. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

368. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

369. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

370. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

371. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

372. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP033036 (Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
atggtcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
*   **   *.********************.** **

373. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

374. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NC_003064 (Agrobacterium fabrum str. C58 plasmid At, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
atggtcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
*   **   *.********************.** **

375. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

376. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
agctcgagtgcctcttcctggtcatgggtgacgaaga	Protospacer
***..    *.********************.** **

377. spacer 10.8|3825077|37|NZ_CP014859|CRT matches to NZ_CP033024 (Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence) position: , mismatch: 9, identity: 0.757

agcctcctggtctcttcctggtcatgggtgatgatga	CRISPR spacer
atggtcagcgcctcttcctggtcatgggtgacgaaga	Protospacer
*   **   *.********************.** **

378. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013634 (Rhizobium sp. N324 plasmid pRspN324d, complete sequence) position: , mismatch: 9, identity: 0.719

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
cttccctcgtgccggatcgcctccaacagcaa	Protospacer
 *. ** *** ****************  *. 

379. spacer 13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011515 (Mitsuaria sp. 7 plasmid, complete sequence) position: , mismatch: 9, identity: 0.727

gggtcgtcggtggccttcccggcgcgctctgcc	CRISPR spacer
ccgtgggcggtggccttcccggcgcgcaaggag	Protospacer
  ** * ********************   *  

380. spacer 13.3|4574448|33|NZ_CP014859|CRISPRCasFinder,CRT,PILER-CR matches to KJ410133 (Mycobacterium phage Jolie2, complete genome) position: , mismatch: 9, identity: 0.727

gggtcgtcggtggccttcccggcgcgctctgcc------	CRISPR spacer
tggtcgccggtcgccttcccggcgc------ccgagtaa	Protospacer
 *****.**** *************      **      

381. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 9, identity: 0.719

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
taggcctcgtcggcaagatcgacatgcagcga	Protospacer
    *  **********.******** **** 

382. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tcgactacgccggcaaggtcggcatgaaggtg	Protospacer
 *  * ***.***********.*******   

383. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_008757 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence) position: , mismatch: 9, identity: 0.719

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
agctcaacggcggcaagatcgacatgagctcc	Protospacer
* ..***** *******.*********. . *

384. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 9, identity: 0.719

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tgcccaatgtcggcaaggtcgacgtggtcggc	Protospacer
  .****.***************.**.   **

385. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to MK305891 (Streptomyces phage Gibson, complete genome) position: , mismatch: 9, identity: 0.719

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
cgcacaacgtcggcaaggtcgtcacgatcagc	Protospacer
  . ***************** **.**   **

386. spacer 16.7|5411840|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_019387 (Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence) position: , mismatch: 9, identity: 0.727

cctccg-----tagtagccccggcgaagtcctccaggg	CRISPR spacer
-----ggaggttagtggccccggcgaagtccaccaaga	Protospacer
     *     ****.*************** ***.*.

387. spacer 16.7|5411840|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP015268 (Mycobacterium chimaera strain ZUERICH-2 plasmid unnamed 1, complete sequence) position: , mismatch: 9, identity: 0.727

cctccgtagtagccccggcgaagtcctccaggg	CRISPR spacer
ccgccgtggtagccccggcgaagtgcactccac	Protospacer
** ****.**************** * *.  . 

388. spacer 16.10|5411658|32|NZ_CP014859|PILER-CR matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 9, identity: 0.719

tgtgtgtggtcggtcaggccgcgagacgcagc	CRISPR spacer
tttgtgtggccgggcaggccgcgaggagtgct	Protospacer
* *******.*** ***********. *.. .

389. spacer 17.2|5551145|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017079 (Novosphingobium resinovorum strain SA1 plasmid pSA4, complete sequence) position: , mismatch: 9, identity: 0.727

gttgcttgcgcccaagtccatgggacctaatcc	CRISPR spacer
ctggcttgcgcccaagcccaagggaccgatcga	Protospacer
 * *************.*** ****** * .  

390. spacer 17.2|5551145|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013073 (Sphingobium indicum B90A plasmid pSRL3, complete sequence) position: , mismatch: 9, identity: 0.727

gttgcttgcgcccaagtccatgggacctaatcc	CRISPR spacer
ctggcttgcgcccaagcccaagggaccgatcga	Protospacer
 * *************.*** ****** * .  

391. spacer 17.2|5551145|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP005190 (Sphingobium sp. MI1205 plasmid pMI1, complete sequence) position: , mismatch: 9, identity: 0.727

gttgcttgcgcccaagtccatgggacctaatcc	CRISPR spacer
ctggcttgcgcccaagcccaagggaccgatcga	Protospacer
 * *************.*** ****** * .  

392. spacer 17.3|5551206|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 9, identity: 0.727

ccgggcagggggccgccggtgccccggcacggg	CRISPR spacer
tggggcaaggggccgccggtgccctggcgttac	Protospacer
. *****.****************.***.. . 

393. spacer 2.5|365200|37|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 10, identity: 0.73

gccgcaccga----gggtcagcgtcgcctcggtctcccgca	CRISPR spacer
----cggcggaaatgggccagcgtcgcctcggtctccagcc	Protospacer
    *. **.    ***.******************* ** 

394. spacer 2.8|365422|37|NZ_CP014859|CRT,PILER-CR,CRISPRCasFinder matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 10, identity: 0.73

gccgcaccga----gggtcagcgtcgcctcggtctcccgca	CRISPR spacer
----cggcggaaatgggccagcgtcgcctcggtctccagcc	Protospacer
    *. **.    ***.******************* ** 

395. spacer 3.2|1157655|37|NZ_CP014859|PILER-CR matches to KR053197 (Gordonia phage GRU3, complete genome) position: , mismatch: 10, identity: 0.73

caacggcggtggcgaccgaccgggtggcgggtccaac-	CRISPR spacer
gggcggcggtggcgtccggccgggtggc-gacgcatcg	Protospacer
 ..*********** ***.********* *.. ** * 

396. spacer 4.2|1200794|37|NZ_CP014859|PILER-CR,CRT matches to MH976512 (Gordonia phage Geodirt, complete genome) position: , mismatch: 10, identity: 0.73

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgccaggttccgcaccggcaccggcacccgcgccg	Protospacer
  * *  *  ******** ***** ***********.

397. spacer 4.4|1200942|37|NZ_CP014859|PILER-CR,CRT matches to MH976512 (Gordonia phage Geodirt, complete genome) position: , mismatch: 10, identity: 0.73

tgttcgcgcgtccgcacctgcacccgcacccgcgcca	CRISPR spacer
gctgccaggttccgcaccggcaccggcacccgcgccg	Protospacer
  * *  *  ******** ***** ***********.

398. spacer 4.17|1201237|34|NZ_CP014859|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.706

accctgtctggtcgatcacctcggcggacggaag	CRISPR spacer
gcttcacctggacgatcacctcggcgggcggcgg	Protospacer
.*.....**** ***************.*** .*

399. spacer 4.17|1201237|34|NZ_CP014859|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 10, identity: 0.706

accctgtctggtcgatcacctcggcggacggaag	CRISPR spacer
gcttcacctggacgatcacctcggcgggcggcgg	Protospacer
.*.....**** ***************.*** .*

400. spacer 5.2|1279849|34|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021919 (Sagittula sp. P11 plasmid unnamed5, complete sequence) position: , mismatch: 10, identity: 0.706

cacaacgacgtctacggcgacggcgagtcgggca	CRISPR spacer
aacaacgacgtgtacgtcgacggcgtgcgcgatc	Protospacer
 ********** **** ******** *.  *.. 

401. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_010311 (Streptomyces sp. HK1 plasmid pSHK1, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gctgccgccggggggatcaccgcctcgtgcag	Protospacer
** *******.************  . .*. .

402. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

403. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

404. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP029339 (Streptomyces sp. SM17 plasmid pSM17A, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gctgccgccggggggatcaccgcctcgtgcag	Protospacer
** *******.************  . .*. .

405. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

406. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

407. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

408. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

409. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

410. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

411. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
gcagccgccgcgaggatcaccgccggtgccga	Protospacer
********** *.********** . .  . *

412. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK962628 (Achromobacter phage vB_AxyP_19-32_Axy09, complete genome) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
cacgccgccgatgcgatcaccgcgataggcgt	Protospacer
   ******** * ************  *.  

413. spacer 6.1|1281353|32|NZ_CP014859|PILER-CR matches to MK962640 (Achromobacter phage vB_AxyP_19-32_Axy23, complete genome) position: , mismatch: 10, identity: 0.688

gcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
cacgccgccgatgcgatcaccgcgataggcgt	Protospacer
   ******** * ************  *.  

414. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_010311 (Streptomyces sp. HK1 plasmid pSHK1, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggctgccgccggggggatcaccgcctcgtgcag	Protospacer
*** *******.************  . .*. .

415. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

416. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

417. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP029339 (Streptomyces sp. SM17 plasmid pSM17A, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggctgccgccggggggatcaccgcctcgtgcag	Protospacer
*** *******.************  . .*. .

418. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

419. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

420. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

421. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

422. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

423. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

424. spacer 6.3|1281352|33|NZ_CP014859|CRISPRCasFinder,CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 10, identity: 0.697

ggcagccgccgaggggatcaccgcgatccgtca	CRISPR spacer
ggcagccgccgcgaggatcaccgccggtgccga	Protospacer
*********** *.********** . .  . *

425. spacer 10.3|3825020|33|NZ_CP014859|PILER-CR,CRISPRCasFinder matches to MH271318 (Gordonia phage Trine, complete genome) position: , mismatch: 10, identity: 0.697

ttacaccagcgcgggcgggaactccggggcgtt	CRISPR spacer
cacgaccagcgcgggcggggactccgtggtcca	Protospacer
.   ***************.****** **. . 

426. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP021026 (Rhizobium sp. TAL182 plasmid pRetTAL182b, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

427. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013597 (Rhizobium sp. N741 plasmid pRspN741b, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

428. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013501 (Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

429. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013507 (Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

430. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013518 (Rhizobium sp. N113 plasmid pRspN113a, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

431. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013491 (Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

432. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013513 (Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

433. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013496 (Rhizobium sp. N621 plasmid pRspN621a, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

434. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013591 (Rhizobium sp. N871 plasmid pRspN871a, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

435. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP013603 (Rhizobium sp. N731 plasmid pRspN731b, complete sequence) position: , mismatch: 10, identity: 0.688

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
atcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
****.****** ************ . ..  .

436. spacer 12.4|3928708|35|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 10, identity: 0.714

aggaaggacttccagcgactccggttcgggctccg	CRISPR spacer
ccccggctcgtccagcgactccggctcggactccg	Protospacer
    .*  * **************.****.*****

437. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 10, identity: 0.688

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tttccaacgtcgacaaggttgacatcgccgac	Protospacer
 .**********.******.***** .   .*

438. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 10, identity: 0.688

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tttccaacgtcgacaaggttgacatcgccgac	Protospacer
 .**********.******.***** .   .*

439. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
tcgattacgccggcaaggtcggcatgaaggtg	Protospacer
 *  . ***.***********.*******   

440. spacer 16.5|5411718|33|NZ_CP014859|CRISPRCasFinder,CRT matches to MN693761 (Marine virus AFVG_250M219, complete genome) position: , mismatch: 10, identity: 0.697

gtcctcggtttgcagatcgcttcgcacgtcgca	CRISPR spacer
cccagacgtttgcagaccgcctcgcacgtcgag	Protospacer
 .*    *********.***.********** .

441. spacer 17.1|5551084|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 10, identity: 0.697

cgcccacgcgcccttcttcgtggggtcgacctg	CRISPR spacer
ccgtgacgcgcccttcttcgtggaggcgatgaa	Protospacer
*  . ******************.* ***.  .

442. spacer 17.3|5551206|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.697

ccgggcagggggccgccggtgccccggcacggg	CRISPR spacer
tgctgcagggggccgacggtgcccaggctgcga	Protospacer
.   *********** ******** ***   *.

443. spacer 17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022660 (Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence) position: , mismatch: 10, identity: 0.697

ctcgccgtcgaccatcaccctgcgagatccact	CRISPR spacer
taaaccgttgaccatcaccctgccagataccag	Protospacer
.  .****.************** **** *   

444. spacer 17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045061 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence) position: , mismatch: 10, identity: 0.697

ctcgccgtcgaccatcaccctgcgagatccact	CRISPR spacer
taaaccgttgaccatcaccctgccagataccag	Protospacer
.  .****.************** **** *   

445. spacer 17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045054 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence) position: , mismatch: 10, identity: 0.697

ctcgccgtcgaccatcaccctgcgagatccact	CRISPR spacer
taaaccgttgaccatcaccctgccagataccag	Protospacer
.  .****.************** **** *   

446. spacer 17.4|5551267|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045058 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence) position: , mismatch: 10, identity: 0.697

ctcgccgtcgaccatcaccctgcgagatccact	CRISPR spacer
taaaccgttgaccatcaccctgccagataccag	Protospacer
.  .****.************** **** *   

447. spacer 17.6|5551389|33|NZ_CP014859|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 10, identity: 0.697

gttccccgcttcgatctggtcgaccttggacga	CRISPR spacer
tttccccgctccgaactggtcgaccgcgcggag	Protospacer
 *********.*** ********** .* . ..

448. spacer 5.2|1279849|34|NZ_CP014859|CRISPRCasFinder matches to NZ_CP035502 (Sphingosinicella sp. BN140058 plasmid p1, complete sequence) position: , mismatch: 11, identity: 0.676

cacaacgacgtctacggcgacggcgagtcgggca	CRISPR spacer
gcggacgatgtctacggcgtcggcgagtgccaga	Protospacer
   .****.********** ********   . *

449. spacer 6.5|1281474|34|NZ_CP014859|CRISPRCasFinder,CRT matches to AB854109 (Ralstonia phage RSB3 DNA, complete genome) position: , mismatch: 11, identity: 0.676

gacatggtcacggacgacacccgaggccgagcag	CRISPR spacer
ttcccggtcatggccgacacccgaggccgctggt	Protospacer
  * .*****.** ***************   . 

450. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP006991 (Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence) position: , mismatch: 11, identity: 0.656

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gtcgtcgcgtcccgtatcgcctcccggtcatt	Protospacer
.***.********* ********* . ..  .

451. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to NZ_CP021128 (Rhizobium sp. Kim5 plasmid pRetKim5d, complete sequence) position: , mismatch: 11, identity: 0.656

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gtcgtcgcgtcccgtatcgcctcccggtcatt	Protospacer
.***.********* ********* . ..  .

452. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to CP007645 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803d, complete sequence) position: , mismatch: 11, identity: 0.656

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gtcgtcgcgtcccgtatcgcctcccggtcatt	Protospacer
.***.********* ********* . ..  .

453. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to KY969628 (Mycobacterium phage Zenon, complete genome) position: , mismatch: 11, identity: 0.656

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gatgcagcgtcccggattgcctccaattggct	Protospacer
. .** ***********.********..   .

454. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to MH001447 (Mycobacterium phage Nilo, complete genome) position: , mismatch: 11, identity: 0.656

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gatgcagcgtcccggattgcctccaattggct	Protospacer
. .** ***********.********..   .

455. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to MH926059 (Mycobacterium phage Riparian, complete genome) position: , mismatch: 11, identity: 0.656

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gatgcagcgtcccggattgcctccaattggct	Protospacer
. .** ***********.********..   .

456. spacer 11.2|3877264|32|NZ_CP014859|PILER-CR,CRT matches to KT591076 (Mycobacterium phage Weiss13, complete genome) position: , mismatch: 11, identity: 0.656

atcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
gatgcagcgtcccggattgcctccaattggct	Protospacer
. .** ***********.********..   .

457. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP021026 (Rhizobium sp. TAL182 plasmid pRetTAL182b, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

458. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013597 (Rhizobium sp. N741 plasmid pRspN741b, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

459. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013501 (Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

460. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013507 (Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

461. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013518 (Rhizobium sp. N113 plasmid pRspN113a, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

462. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013491 (Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

463. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013513 (Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

464. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013496 (Rhizobium sp. N621 plasmid pRspN621a, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

465. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013591 (Rhizobium sp. N871 plasmid pRspN871a, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

466. spacer 11.5|3877263|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP013603 (Rhizobium sp. N731 plasmid pRspN731b, complete sequence) position: , mismatch: 11, identity: 0.667

gatcgccgcgtcccggatcgcctccaacctcgc	CRISPR spacer
catcgtcgcgtcacggatcgcctcccggtcgtt	Protospacer
 ****.****** ************ . ..  .

467. spacer 14.1|4628753|33|NZ_CP014859|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.667

gtgatgcgtgctcgcggccggagccggagtgtc	CRISPR spacer
acaccgcgtgctcgcggctggagccgcagccga	Protospacer
... .*************.******* **.   

468. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 11, identity: 0.656

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
gtgtcaacgtcggcaagatcgacaagatcgag	Protospacer
.. .*************.****** **   . 

469. spacer 14.2|4628814|32|NZ_CP014859|CRISPRCasFinder matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 11, identity: 0.656

actccaacgtcggcaaggtcgacatgaagcgc	CRISPR spacer
gtgtcaacgtcggcaagatcgacaagatcgag	Protospacer
.. .*************.****** **   . 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	316376 : 363497	45	Mycobacterium_phage(11.11%)	integrase,tRNA,protease	attL 316253:316296|attR 327413:327456

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP014859|316376:363497|DBSCAN-SWA
GCTACTCGGCCCAGAGGGCGGAGCCCATCAGCTCGGCCGCGTCCCGGGTCATCTGGCTACTGACGTGCGTGTAGCCCTCGGTGGTGCGCACGTCGGAGTGACCGAGAATCGCTTGGATCGTACGGACGTGCACGCCCTGTTCCGCTAACAGCGTCCCTGCCGTGTGCCGGGCATCGTGCGGGCGGACGTAGCGAACGCCTGCCGCCCGCAGCAGCTCGCCCCACTCCTCCCAATCCTTCCGATGATCGATCGGTCGGCCGTTCGGCTGGCAGAAGACGAGGTCCCAGTCCTCCCACGTTGAGCCTGCTGTCTGTCGTTCCGTCTGTTGCCGGGTGCGTTGTCGCCGTAACAGGGCGACCAACGGACCGGGCAGTGTGATCGTCCGCCGTCCCGTGCCCTTTGGCTTCCGGAACACCACACCGCCGCCATGCCGATCGGGGCAGTGTCGAGCGTGACTCACGCAGCCAGGCGGACAGGGCCGGGGGCACTTGCCCTTGTGCGTGGCGCACTTCCGCTTGCACGACTTCTTGTGGAAGGCCGATCCACAAGCGTGCGCGTCCGTACAGCCGTGCCGCCAGGTGTTGCGCTGTGCCTGCCACCAGATCCGCACGTCGCCGGTCTCCAGATCGACGTACTGCCACCGCAGCCCCAACACCTCACCCTGCCGTAGGCCACACGCCAGCCCAACAGACCATCGAGCGCCGTTCCGTCTACCCGCACAGGCGGCGAGAACATTGCGCGATTCGCCACGGCTCAGATGTTGTTGCTCCACCCGTTCTGCCGTCGGTGGGTCGATCAACTCGGCCACGTTGCGGGCGACCTTCCCGCGTCGAACTGCGATCTTCAGCGCCCGAGAAAGGATGCGATGCACCTTGAGGACGTGCGACGGTGCCAACTTCGCCCGGAACATGCTCCCGTACATCGCGTCCAGGTGCTCCGCCTCCAGCCGATCAAGGCGATGTTGGCCGAGGAGAGGAATGATCCAGTTGCGCGTCTTCGACCAGTAATCGTCGTAGGTGCGAGGCGCCACCTTCTGCACGGCGATCGTGTCGAGGTAGACCGTCATCCAGTCTTGAACCGTGGGCGAACGACCGGCTTTCCGCGACTTTCCGGCATCACGCTGTTTCTCCAGCGCCTGCACCGCCTGAGTTGCGCTCTTCTCTGTCTTCCTCTTGACGTGCCTACGGTCGAGCGAGCCGTCTTGCTTCACGCCGACCGTGACCCAGCCGTGCCACAACTTATCCGCACCGAGATAGATGGATGATCGCCCATTCGGCTTCCGCGTGCGTTGCTCTTCCATCACGCCGCCTCCGCCTGCTCGGATTCCAAGGAATGCAGGAACTCGGCCAACGCAGCACGGGGAACCCGACGACTGCCGCCGATCCGCACCGACCGAAGCTCACCCGAATTGATCAGCCCGAACGTTCGAGTACGGCCAATGCTCAAGATCGCCGCCGCTTCTTCGACTCGATACAACAACTTGTCCATCTGTTCCCCCAGGTCATCAGGCTGCGATAGGAGTTGCCGAAAGATGTGGTTCGCCGCCTGGTGGTGGTTGTGCTGCTTGGAGTGCTCGGTCGTATTCGGTTTTCCAGGTGAGGCGCTCAGAGATGGCGTGCATGAGGACGTGTGCGCGTGGTGGTACGCCGGGGTCGCCGGGTCGGACCTTCTGCCAGCCCAGCCGTGGGCTGTCCCGTGGTGGTTTCTCGATCCCGGCGGCGGCCAGGGTTTCGACGACGAAGCGCTTGCGGTCGGCTCGGTGGTCGGCCAGGGATTTCCCGGACCACTTGCGGGACACCAGCACCCGTCGGCCGGGCAGGCCGAGGGTGGCGCGTCGGTGGGCTTTCCCCTTGCAGTGGGCGGAGGCCATCTGAGAGCGAGCACCTTGGGGTTGAACGCCGTAGCGCAGCCAGATCGGGCATCGGGGTGAGCACGGGGTGATCGAGAGTTCGGCGTGCAACCGGTCGGCGTGTTCGCGTTGTCGGGTGGTGTCTTGTTCGACGACCTCGGAGACCGATTTGGTGAGGTACTTGGTCAGATACCCGATGTGGCGTCCGGCTTCTGGGGTGCCGCCGAGGATGCCTTTCGAGTGGACCTGTTCCCCGAACGTCGAGACATGCACGGGCACCTCCAAATCGGCGACGGCCTCATCCCAGGTGGGCAGTGCTTGCCGGGTGTCGGGGTCGACGAAGCTGCGCCGGTCGTGGTCCCAAACGGGCAGGTGCGTGCCGTCGTAGACGGGCTGGTTGTGGTGCGGCCACCAGACTTGGTGATAGGTGGCCGCAGTGACCTGCTTGACGACGTCGTGCGGGATGGAACCGCGGATAGCGGCGTGCAGATGCGGCGCCCCGCGCTTCTGTGGTTCGACGGTGGCGAAGTACTGGACGTCCCAGCCGAGGCAGCGTCGGAGGTTCTGCCACCACCGATCGACCAGTGCGGCGAAGTGCACGATGTCGCGGGCAGCACGGCGATAGTCATACGTCGCGAAGTTCACCGGAGTCCCGTCGCGGCGGACCTTGCCGTAGGTGTCCAGGGTCAACGTGATGAACATCGAGGGTCGGAACTTGCCCGCGTATTCACGGCCGACCGTCCGCTTCTCCACTCTGCGGCGAGGGAGATTCGGGGCGTCTTGCCGTCGCCGGGTCGAGCGCTTCCGGGCCGCCTTGGCTGGCACATCGGGGTTCGGGAGCTTCCCCCGGACACCGAGGTCCCGAAGATCGGTGTCAGCATCCCGGATGGCTTCCCGGAGTTCCTCAGCGTCGGTCTCGGCACCCTCGGCCAGGGCCTTGCGGTAGTCGGTGACCAGGTCCGCGCGGTAGGTCGTCAGGAGTCGTTGTTGTTCGGTCGGTGGTTCCGGGGTGAAGTCCGGTTCCTCATCCAGGTGCCAGCCCTCGCGGCATTGGGTTCGCCGCAGAGCCCGAGCCTTGCGAGCACACGGCCCGCAGATGGATTCGACGGTGGAGCCGCAGGGGACGCCGACGTAGCGCATGTCGCCGGTGTCGTAGTCGACGGTCTCCATCATGAACGGCCGGATACACACCCCGTGGTGGTCGGCGGTGGCCTCGAGGACCTTCCCCGCGAGGGGTTGGCGCATCCGCTCTGCGCGGGTGTGGCCCTGAACGTCGGTGGGTGTGGTGGTGAGTTCGGTACTCATGCCGCCTCACCGACCACGTCATCAGCGTCCGGATCAGCGTCAACCGTCCGTGCAGGCAGCTCGTGCACCGTTGCCGAGTCGGTGGCATCGGCGGTGACGTAGTCCACGAGTCGATCAAGGTCGCCGTCGGTGATGTGGAACGCGCGAGCGCGGACGGGTTCCCGTCGGTCGGTGTACTTCACCCACGCGACACCGGGGGTGGTTTCGGAGATCTCGTGTGCGACTGCTCCGCGTTCCCGAACACCGTCGCCGAGGACCATGTCCACCTGGCCGGGCTCATCCAGCCGCAGGGCGATGCGGGTGGGGAACAGGTGTCGGAAGCTCAGGATTTCCTTGCGTGGGTCTTGGATCTCTCCGATCACGCAGACGCCGGGTGCGCGGCCTTGGCTGGTGATGGTCTGCAATGCCGAGTTGGCGCGTTCTTTGAGTTTGCGGTCGGTTTGGTAGGCCACGACGTCGGCGAGTTCATCGACCACCAGGAGCAAGAACGGCACTCCACAGTCGACAGACCACCTGCGCTTGCTACCTCGGAACGAGGCCGCCCGTTGCTTCACTTCCGTGGCGAGTTCTTCGAGGAGTTTTACCGCAGCAAGGCCGTTGTCGAACACCAGCCGGTGGAACAGCTCCGGTGCTTTGCCGAGCTCCATCCCACCCTTGGGATCGATCCCATAGACCCGGATGAGGCCGGAGCGCAGCATTGGAGCGAGAGACCAGAGCAGGGACCAGACCACTGAGGCCTTACCCGCCCCTGTCGCGCCGACGGCCAGGAGGTGGGAGCCGAAGAGCCGCAGTAACCAAGGTCGTCCGGTTTCGGTGGTGCCGACGGGAACGCGTTCCAGGTCCTTGGTGGGGGTGGTGTCGTCGGTGCCATCGGGCAGGGATGGCGGCGGGACGGGTTGGGTGAGTGGGTCGCCGTGGATCAGGTCGAGCACGATCCGGCGAGGCCCCACGACGCGGACGCGGCACGTTCGGGCGTCGAAGGAGTGCGCCAAGGCCTCGGCACGGGTTTCGAACTCACCGGGTGTTTGACCGTGCAATAACTTGACGGTGACCCGGTCCCGCCACCCATCAGCGCGCACTCGGATGAACGTCGGGACGTGGACCTTGCCGTTGACGGTGCGTTCGAGGTGGCAGAACCGCATGGTGCGTAACCACACCGGGGTGTAGACGATCAGTCGTCGCCATTCCGAGCGGATCTCGACGAGCACCAGGCGCACGAACGACGGCCGAAACCGCCACCACCAGCCCACCAACACCAGGGCCAGGATTGCGCCGAGGATCAGGGCCACCGGCCAACCCCACCCGTGCCAGGCGACGACGAGCACCAGGACCACGGCGAAGGCCAACGGATACCGCGCCGCCTTCCTCGCCACCACGACCGTCAGCCACACGGCCAACCCGACGGCGATCAGCGGCGCCACCAGGACCAGCGCCCACCGGGGCGAGTGCGTCCACCACGGCAACCGAGGCCGGGCGACTTCCAGCGGTGCGGGGTCGATCCACCTGCTGCGCTCAGGCATTGCGACCACCCCGCACCGAGTTCACGGCCGGACCGAAATCGAGGGGAAGCCAACCGAGGCAGCGCAGGCATGAGGGGTGGCCGGGGGCGAATTTGCCGAACTTCTTGCAGGTGGGGCACCGACGCGGACCTGACGTTAAGTGAGGACTTGACACGTTGCGTGGTTGCTCTAAGCTCATGGCTGTTCACTCCGTTTAAAAATGGTTGAAGTGGACAGCGCAGAGGCGGCCGGTTTCCAGGCCTATAACCGCCTCTGCGCCTTTCCCTTTCCCACACCCGCTTTGTTGTTCAGCGGGTGGTCTTGTCAGTCAGTCGCTCGGGCGGCAGTTACGAAACGCCCCCGGATACACCCCGATCGTCGGGACTCTCGCCCGACAGTCCGCGCACTTCCCGCGAGGCGTGCGGACCCATTCCCGGCATCCGCGCGTGCGGCAGAACCAGCCGATATGACGCCGCGACCACACCAAGACACGTCTCATGACGAGGACCACCACCCGGAGCCGCTGATCCCGCGATCCGGTGGGTCCTGGTCCTTTTCGGGCCAGCAGTGGCGCCCCCGACCCTGCGGGATGCCGGTGGGTGGCTCGGGGGTGATCACGGTTCCGCCCGCCGGTCCGGCAGCATGGTCGAGCCACTCGCTAGCGCGGTCGGCGGCGAAGGACAGCGTGCGCAGGAAGTCCGCCATACACGCCCGGCTGAGCTTGTCCGGCGGAATCGGGATCTCCACATGGACCGCGCCCAGATCCAACAGGAACGTAGGCCCGCGTCCGGGAAGGTTCGCGCCGAAGACCGCGCACGCACCGACTGCGGGCAGCACGACGAGCCGAGGTGCGGTTGTCATCGGTCCCCCTCGCGGTGTCCGTCGGCGGCTTCCAGCGCCGCGATGCCTTCCGACACAGCCGAACTCAGCCGGGTCAACGCACCGCGATCGATGACCAGCGCCACCGGGAATGCCTTGCCGAGTCGGATCTCCACGCGATCGGCGAACGGCAGGGCCCGGACTCGCACGGGCAGATCGGCCGTGAGGTGCACAGTGACCATGTCGCGCATCGGGTTCCCCGCCCTCACGCCGCAGCCTGTGCGGTGGGCTGGGACGTCTTGCCCGCCGAGGACCGACCCGCACCGGCACCGGGCGCCCGCATCGATGCCGCCCGCAGGCTGAACGCCACCCGCCCGTTCTGCTCGTAGGCCGTCGCGGTCAACCCTTCGAAGAACACCGGCCGAAACGGCGTCCCCGGCAGGGCATCGGGCGGAATCGGCTGCACGTCAGCGGCGATCTTCACCACGACCCCGGTGTTGCGACCGTTGGCAGCCGGGTCGGTGACCTGCACGTTCCACACCAGACGGCCCGTGACCTTGTCCTTAGCCGGGCGACGCTGGCCGTTGTCGAAATCCATCCCCTGCTCGACACCCAGCACGAACGCCCCATCCGGGAACACGTCGTCGAAGGGAACCGAGAACCGATAACCGTTGGGTACAGGCATAACGCCTCCAGAGGTCATGTCGCCGAGTCATTACGGCGACTCTGACCACCACAATCGGCGTTTCCGCAGGACGTACACACCACACAGTGGGACTTCTCAGGACGTCCCTGCTACGTTTGGAGACGTCCCTCAATGTCCCCGAAGGGGTGATCATGCCCAACGAACGACTACGGGAAGCACTGCTGAAGCAGGGCCTCAACCTCGATCACGTCGCCCGCGCGGCCAACGTCGACCGCAAAACCGTGGAGCGGTGGATCACAAAGAATCGGCTGCCCTACCCGAAACACCGGCACACCATCGCCGCGATGGTCCGAGAATCCGAGAATTACCTATGGCCGGACGCACTGCCCGCCGAACGCAAGGCAGAGGTCGGTGTCTCCGAGGTCGTGAAGGTCTACCCGCATCGCAACGCCATCCCGGTCGAACTCTGGGACCGACTCATCAGCGAGGCGACCAAGCAGGTGGAGATCCTCGTTCACGCCGGACTCTTCCTAGTCGAGCGGCCGACCTTCGTGAAAGACCTCGCCAAGAAAGCCGAGAACGGGGCACAGATCCGCCTGTTGTTCGGCGACCCGGCAAGCCGCGAGGTCGTGCGGCGTAGCGAAGAGGAACAGTTGGGCAAGGCCACCCTCGGAGGTCGTATCCGCAATGCACTGGCGTTCTATCGACCGCTTCGAGCCGTGCCCGGCGTCGAGCTGAGATTCCACAAGACGACGCTGTACAACTCAGTGTTTCGCTTCGACGACGAGATGGTCATCAACACCCACGTCTACGGCTTCCAAGGAGCCCACGCCCCCGCACTGCATCTACGCAGACTCTCCGCAGGCGACGTGTTCGAGACCTACTCGGAAAGCTTCGAAACAGTCTGGGCCGAGTCCAAACCAGCCGACTTCTGATCAGGAGCCGCCCCGATGACACGCACCGACCACTTCCACGACCCCGACGCGCCCCAGCCCAACAGCATCGCTATCGCGGTCAGCGCCTTCGTCCTCAACGAGGCTGGCGACCTACTGATGATCCGACGCAGCGACAACGACCGCTATGCGATCCCCGGCGGACAACACGAACTCGGCGAAACCCTCTCGCAGACCGTCGTTCGCGAAGTGGACGAGGAAACCGGGATAGCCGTGGAACCGACAGGAGTCATCGGCCTGTACTCCAACCCCGCCCATGTCATCGCCTACGACGACGGCGAAGTACGCCAAGAATTCTCCATCTGCTTCCGAGCCCGACCAACCGGCGGAAGACTCCGCACCAGCAGCGAGAGCAAAGAAGCCCTTTGGGTCCCGCGCTCAGACGTGGACAACCTGAACATCCACCCCTCGATCCAGCTCCGCATCCGGCACGGATTCGAGGGACGAACCGAGCCCTTCTACACCTGAACCCCCGCAGCACGAAGCCGCGACTCAGTACGGTTCACCGCTTCCGCCCGCTCAGACAGCGAGGCATTCACAGCGCGGCTCACCGCGTGATCAGGGCCATAGCGCCGACGAACCTCCGCCATCCGCTCTTCGAAACCCACCACCGCGCCATCAGGACCGACCGTCATATCCGCCCACCACAACGCATCCCGCACCACCGTCGGACCCTCATCAACGAACTCACCCAACGACGACGCAAGACCAGCCAACTCCGCATCCCACCGTGCAGCCGAGTGAAACGCCACCAGACCCACGACCCGCTCATCCACACCGAGGCCGCGCAAGAAGCGAGCGCCATCCAACGAGTGCAGACCGGTCGCCGCCAACTCCGGCGCATACCCGACGTCATGCAACACCGCCGCAGTCCACAACACCCCGGCACCATCACCCACCACCACGCTTGCAGTACCGGCACGCCGAGCCACCGCCTCCACATGCGCCCACCGCTGCGGCAACGACACCGACAGACGTTCACACGCCAACTCGTAAGCCCACGACTCCGACCGCACCAACCAACCGTAACCGCCCAGTCACGCATGTCTACCGAAGAAGACCAAAGCTTTGCGTGCATCCACAGCGCCGCACCCCACCGGCTAAGACATGGTGAAGCGAGTGATCAGCGAGCAGCGGACTACTACGACCGTCTGAGTTGGTAACTCACAGTGTCCAGGCGTGTACTATGTTTTCCGAGTTGTCAGGCCGGGCTGATAGTTACGTGACTCAAGGAAGGCGAGTGCGTGAGCGAAAATCAGCGCCGTACCCAGAAGCGGTCGATCCCAGACCGGAACATTGTTGATTCGTCAAAAGTCAACCGCCGGATTGATGCACGGAACTCCATTGATGCTGAAAACGTCTCAAATGTAGTCCAGGCCAATCAGATAAATGGCGATATCGTTATATATGAGGCGGGGCCGCGAGGCACTGAAAAAAACGAAAGTTCGTACCGTCGTGCGCGCCGAATAGGAGAGGCTGGAGGAGGAAGTGCGCCTCCCGTCAAGAGGGGCCGCATAGGACGCTACATCGATCAATCCATCGATTCTCGATCGCCCATTTTAATATGGGGTATTCTATGTATTACGGCAAATTTTTCACTCGTCTATTTTGTCGAGTATGCGTTCGGAGGGCAGCAGCCCGGGGAAGATGCTGCGGCGGACGGAGAGAGCGCCGTAGTTGCTGCGGCAGTATGTGTGGCAGTAGTTCTAGTTGCTCTCTGGCGTAACTACGCGCGGCGAAGGGGATCTGGGAAGTGGAAGTCCTTACGCGAAGTGCATCCCAGAATCGTTAACGTTCTCGAACAAATCATCTTCGTCGGTCCCGTGATTGCGCTTCTGCTGGCGTTGGCACTATTCGCCGTCTCAGGTACGTGGCAACCAGGTGCACTCTTGATGTCAGATTCTGTACCAAGCGAGTCCATGCCTTCGACTCTGAGTCATTTCGGGCTCTCGCTACTCGTCACTCTCGTCCTTTTGGAAATTGCCGCATTCTGCTTCTATGTATATTGGAGAAGCCTATGCGCGACGGTTGACCCGATCCCGAACGAAGTTCCTCGCCGGGCAACCAAGTCGCGAGAATGACGTCTTCTGCTGCCGAATTTGGCTCTAGGGGATCAAGGCGCGCCGCCTGCGGCGGCGCGCTGGTCGGTCACCTTGAGCAGGCCGGGCGCACGGCTCAACCCTGCGGGCGCGCTGACGCGCGTCCTCGGTCTGGCCGACGCCCAGCCGCCTGGTGCCGGTGACGCGCCACCGCAGACGGCGCGCGAGAAGACCGAGCAGGACTCAGCAGCCACACCGGTCCGACCAGAGCGCCGAGGGGTCATCCTGGTAGAGCCGGTCATGGCGCTCGACTGCCGCGACGGCTTCGCCGCCTTGCCATCTAACAAAGGTCGTCTACTCGGCGGATTCCTTCCACTCTCCCTTTTTTATAAGCGACAGAGGGGTCTCGCCGGGAATTTTGTATGACCGACCTTCCCATCCGATTTTCGTTCTGATAGTGATCAGCTCATTTTCGTTGTAACTCTCGGGAGGCCAGGGTATTGTGGCCGAAAAAACTCGACTGTACAGCTTCTCGCGGTCGACGCGTTGTCCACACTTATCGCACGTGGGTGAATTGATTTTTACCTCTTCGAGGATCTCGGAGAAAGTTTCAATTGTTTCGACTGAAGGTTGTCTTACGAGGGCTACCGGCTCGGTGCAGTCGCAGGCATAGAAAATTGTGAGGTAGGGTATATAGTGACAATTTGGGCATCCAACTGAGTTGTCCCCGAATGTTGAGAACATTAGCGGGTGATTGCAAAAGGGGCATGCCACATGTCCACGGTAGAGGAGACTGGCAACGGCGTGCTTTCGCGCATGTCGCCGCCATCTCTTCAACGCCTTCCTTTTTGATGCCTGGATTATTTTCAGGCTTAAGTCGATTTTCTCCGAGAGCGTCGGGTCGACTACGTAGCCGTACCGAGTTTTCATCACGTCGGTATTTATGCCGTGAAGCATTCTGGGTACAAGCGGTTCAAGAAGGCTTTTCTTTAGGATGTCTATTCTGATTGTTGCGCGTGTGCGTCGCGCGGGTGCGATTTGCTCATAGATCATTCTAGAGTAGTTCTCAAATATCTTATCGTCTGTGAATTGTTGCACGGGAAATACCGTCCGGAACCTGCTGGCGAAGATGGCTTTCCCTACGTCGAGGTTGATGTTCATATCTCGGATGCACACGGTTGTAATGGCGGCGATGCTACTGGGCGCTTGGTGTTCTGCCTCGAAATCTTGCGCTGCCATTCGCCACTCTGAGATCACCCCGCTTTGCGCTACAGATTTCAAAGCTCGCAGATCGTCTATCAGCGTCCTTGCCTTGCTTCCGGAGAGTGATCCCGCTTCCAGCCTAAAGACCATTCCGTTATTGTCCGAGGTGTTACTGTAAAGTTTTGAGAACTTCTCTATTTCGTTCGTTATGTCGCTGTAGCTTACCGCTTTGTCCTTTACGCTTATTAACGCCCTGCCGTTAGGCCATGAAATTTCAATGTCTTCTAGTTTTTCAAATATAACTAGTCCAGCCTCTGTGAGTTGACGTGCAGGAATTTCGTCGATAAGGCCTCCTATTGCTTCTACTAGTAGAATCATGCAGACGGTGTCTTGGGCTTCGACCCTGCTCGCGAGCTGGCCTCCGCGAAACGTTGGAGAAAATCTATTTGATTCGTGCACCTTCTTGCCTTCCTGTCCGTGTCGATCCAATCTATAGCACAATCTATTTCTTGAATATTTCGAAGCGAAATTCTCCGTTGGATAGGTTCGATTTTTAGCTTAGGTCGTGCGAAGTGTCACTGGTCCAAGCGGATCGAGATGCTGTGTCGAGGGTTGCAGTTCGGGTTGCAGTTCACCCCCGTTCAGCTCGGTCCACAACAGGTTGCGGAAAGCCTCTGACCTGCGGATGAACGATCCTGCACTGCCCTGAACAGGGCTTTGGGGAACTCGTAATGCGTAGGTCAAGGGTTCGATTCCCTTAGGCGGCTCGCAGGTCAGGGGTCCTCTTCGAGGGCCCCTGATCTTTTTGTGGAGCTATCGGTAGAGCTACTGGCTCGCGACTCCCGACATGGGCGAGTGGGACCTACCGGAGTTCCCGGTGCCTACCTCGGCCAGTACCTGGGCGGTGCCTTAGCAGGGTCGACTCGTTCGAAGCGTTGCTTGCTTCCGGGGTTGAAGACATGGTGCATGCCGGATTTCTTGATCGCATCGGTCTCCAGCGGGTCTTCCAGCTGCCGTGCGTCTTTGGTGAGGAAGACTGCGTAACCGCGTTTGGTCGCATCGGGCAGCAACGCGAGATCCTTCTTTCCTGACCACTTGAGCTCGCCGACATGGGAGACCTTGTGGTGAGCTGCGGCCATCCGAGTCGAATACGCCATCCTCCGCCGCCCGCCTGGTGCGATACCGCGCCATCAGTCAGGCCTTCGGGCCGAAGAGGCCAGGCGACCACCCGATATGCCCGCCAGCTACAAGCTGCAGAAATAGCGAACAGGTCCTCCCAGACTCAGCGGGGAGGACCTGTTCGTTCGACGGTCTGGCTATCCGTGGGTGACCCACCTGGCCCGGCAAAACGGGATAGCAAGGAGGAGGCCGCATTGCTGCGGGCGAGGTGTGTCAGCCACCTATCGGTGTGACGGCATCGATTCGACGGCAGTCGGGCGGCGGTGCGCAGCACAGCCCGAGTCGGCTCGTCGGTATCGATCAGTGGAGTCGTCTCACCTGCGTCAACGTCGGTCGCGCGGCGGATTAGGGTCGTTGCCCCGTCGTGAGGTGTCCTTACCTCGAATGCGGCCGTCGGCGCCGTGAATCACCGTTTCTCCACCCGTCCTGGCAGTGGTCTGCCTGGCCTGGCCGATGGCCTGGTTCTGGGTCTGGTGATGGCTGCTCGCCCGGCTGGCATGCGGCTTCTCGACGTTCCAACCGCCGTTGCTGTTCGGGACGACATGCCGATCCTTCTCGTTCCGTCTCATCGGATGCCTCCATTCTGTTGAGTGGTGACGCGAGTTGCATCACTCATGGTGAGAGGCGTACCCCGATCTCGCTACTTGGAACCGTCGATTGAGATTTGGCTGCTTGCCGTCGATGGTGACCTCATCTGGGATACATCGTCGTTGAACTGCATATTTCGCTTGTCGAGGTGGCGCTGCTCTGGGCCGCGGCAGGGCGGCGAAGGTGACTCACCGTTATATCGATCGATGGGAACGTCCCGTGGGAGCGACCGAGGCGGTATCTCGGTGGGGGCGACCGGGTGGTCACGATGCACCTGCCCCGGTCACCGGAACTTCGGTACCTGAACATCTCGAGCGGATCACATGTGCTTTGGGTGGCGGATGAAGGACCGACAGCACCGTTAACGACGGGGAAGGTCCTTCCGACGTGACGGCTGGATAGCTACGCGGTGCAAGATCCTCCAGTCAGAAAGGCTCTGTTCGAGATGACCGACACCCCCAACACGGCGAAGAAAAAGAAGCGTTGGCCGTGGATCGTCGGCGGCATCGTTGCCGTGATCGCCGTCGCCGCTGTTACCACGGGCGGCGAGGACACCACCACCCCGGACACGGCGACGGGCGACACCACTGAAGGCGAGACAGCACCGGCGGAGGACGACGCCGCAGCATCGAACATAGCTACGGTCGTGTATGAGGTGACCGGCACCGGGACCAGCAGCATGATCACCTATACGACTGACGGGCAGACCGATATGGAGCAGGTCGGCGATGTCGAGCTGCCGTGGGAACACACCATCGAATTACCTGCGGACGATCCGCTGCTCGTGGTTCAGGTCAGTGGCCAACAAGCAGGAACCGGCGAGATCTCGTGTCGTATCACCGTCGACGGCGAAGAGGTGGCGCAGGCGACCAGTGATGGCGACTACGTGATGGCAAGCTGTTCCGAGTCGATCGGCGCCTTCAGCTGAGCATGTTTGCTCGTGGTGAGAGGGCAGCGGCACCGCAGAAGACATCGTCGGTGACGCTGGCCCTTCGCTCAGCGAGCTCGCGTTCAGGAACCGGACAGCAATCGGGAGAACATGATCATGTCCCGGTGCCGTTCGCCGATCCGGAGATAGGAACGCAGCGTCCCTTCCTCGGCGAATCCGTTCGCCCGGCAGACCGCCTGCGAGGGGCCGTTGTCCACCTCGACCAGGGCCTCGACTCGAAGCAGATCCAGATCGCGGGCCAGTCCGACGGTGAGTTCGACGGCGGCTCTGGCTAGCCCCTTGCCCCGATGGCGCGGCAGTAGCCAATAGCCCATGGCACCGCGTCGATGCGTCCAGTCGATGCCGTTGATCGTCACCATGCCCGCCGACTCGCCGGTCGACTCGTCGATGATCGCCAGCGGGATGCCGAATCCTTCGGCTGCCTGAGTCCACTGTCGGCGCAACCAGGCCGATGCCTGGACCATCGAGCAACCGGCCGGGATCGTGGTGATGAGCGGGATATACGGGTCGTCGGCTGCCTCGATGATCGCAGGCAGATCGTCGATCTGCCACGCGCGCAGCAGAACTCGGCCGTCGCTTCTGATCGGAAGATCGCGCAGGTCGGCGGCGCGGCCCGGCGGTATCGCTCGGCGGCTCGCCGCGCGAACGGTGCCAGGGTGCCGCTCATTACCCATGTCGCCTTCCTCTGCTCCGCGCTACGGAATGTTCTCGAATTGACACCCTATGCGGACGGCTTGGCCGACGCCCGGACGTCGAACGGGCGCGCTGGATATCCCGCAATGCAGGCGTGCGGGTCTGATCGAGCAGGTGGGATGTCATCGGGGCACCCGACGGGCGTCCGTTCGGCTGCCGCTCGACGAGCACGCGAGTCTCGCGGTGCCCGGACTGTCCGATTGCCGAGGGCGACCCGAACCGGCCAACGGCCTGATCGTTCATGTTCTGTTGGGACGACGGGTCTCTGAGGTTCCGCAACGCGTGTACGCCACGACATGAACCTCCCCGAGGGTGACGACGAGTGTCTTACCGGACGCTCACAATCCGTTGCTCGGCACAGGGAGCCGCACAGTGAGAAAGAGCAGATGGGCCGCCGCAGGGCTGGCGGTGCTGCTGACCGGAGCCGCCTTCGGCACCTCCGTCGCCTCGGAGGAGCCGTTCGTCGATCCTGCCGGTCTCGACCTCGAATCCAAGGGCACCTTCGATGTCATGAGTGACATCCAGGGCGCGCTGGAAGCATTCAACGACGTGCGACTCGCCGCCCACGACCTGGCGCCCGACTCGAAGGCGCTGATGATCAACGGTGACATCGTCGATCGGGGTTACGACTTCGAGTACGACGAGGTCTCCGAGATCATCGCGAGCACGCCCGGTCCCGGTGCGGACACCACCCTGTCCAGCATCGGCAACCACGAGGCGTACTCGCCCGCCTGGTGCTCCCCGACCGAGCTGTGCCAGCCGTCCTGGCCCAACGGTTTCACCGAGGAAGAGCTGTACCAGTCGTTCTTCGACTTCGCAGGCCGCGACCGGGTCTACGACGAGATCGTCGTAGACGGCATCCCACTGATCACCCTGGGCACCGAGCGGTTGATGTGGTGGGAGGACCCCAACCTGGATGACCACATCTACCTGAGCGACGAGCAGTTGTCCTGGTTGCGGGCGCGTCTCGACCACCACACCCGCAACGGTGAGCCCGTCTTCATCGCCACGCACTACCCGCTGGAGAACACCGTCTCCGCCTCCGACGGCACGTCGGGGCAGTTCCATCTGCAGGATCGCGAGCTCCGCCAGATCCTCGGGGACTACCCCCAGGCGGTGCTGTTCAGCTCGCACACGCATTCGAACCTGCGCGAGGACGACTGGGCAACCAGGGTCAAGGTCCCCGGCGGCCACCCGGATGGATTCACCGCGGTGAACACCGGTGCCGTGCTCAACCGGCAGGTCATCCAGGTCACCGCAGGCTCGGACGGCGCTCGGATTCGCGCTCGCGACGTCGCGGCAGGCGAGTGGATTCAGGACTTGGTCGTTCCGACCGTCGACCCGGCCGAGCCCGCCTCCGGGCTGCTCGTCGAGCCGTCGCAGGACAACATCGCGCCGGGCGGGTCGGTGGAGATCGATGCCGAGTTCGTCAACCTCGGCAGCAAGCGCCTCATCCACGCCGGACTGGAGCCGGTCGTTCCCCAGGGCTGGCAGGCCGAGTTGGTCGAGCAGAGCGGTCCGAAGCACCTGGACCGAGGCGCCACCACGTCCGCGACCTGGCGGATGACCCCGCCCGAGGGTGTCGAGGCCGGGGATGTGGAGTTCGCCGTCGACGCAGTGCACGGTCGGGGCAGCAAGGCGACCCGGGTCACCGAGCAGACCGAGGTCCAGATCGTGTCGGCTCCCGCCGGGGACGTCTTCGTCTCCGACCTGCCGTTCCTCACCGCCGAGAACGGTGTCGGACCCGTCGAGCGCGACCAGAGCAACGGCGCGATCGGCCGGAACGACGGTCATCCGCTGACCGTCGACGGCGTGACCTACGAGAAGGGCCTCGGCACGATGGCCCCCTCCGAGACCACCTTGTATCTCGGCGGTGAGTGCGCCCGATTCGCCGCGTCCGTCGGCATCGACGACCGTGCGCCGCAGTCCTCGCAGAACCGCCCCGACGATGGTCGGGGCGACGGCGGCGACGTCGTGTTCCAGGTCTGGGCCGACGACGAGAAGGTCTGGGACAGCGGTCTGGTCTCCTCGGGAGAGGGAGCCAGGGACATGGACGTCCACCTCAACGATGCCGAAACCCTCCGGCTGGTCGTCACCGATGGCGGCGACGAGAACTGGTGGGACTACGCGGACTGGGGTCAGGCTCGACTGACCTGCGCAGGCTGACCGAACCCGGTGGTATGACGGCGGTCGGTCGAGATGACCACTCTGGTCGCTCGGCCGACCGCCTGTCGCTTGCAGGCCGCAGCTCTCCCGTCTGCCATGTCATCATCGATGCCTCGAGTCCGTTTCGGCCCGGGTGTGCACATCGCGAAGGGCGGGCAATTGGGGAGACAGACCGGCCAGGCGCGTGGGCAGCACATCCCGGATCCGGTGGATACCAACCACTCCTCGGGCGATGGGCGGGTCGAGCGGGGGAATCGGACGCGGCGGGCGGTATTGCGGCACGCCGTCGACATCGCCTCGGTCGACGGCTTGGACGGCTTGTCGATCGGCAGGCTCGCGAGCGAACTGGGCCACAGCAAGAGCGGCATCTTCGCTCTCTTCGGCTCGAAAGAGGAATTGCAGGTCGCGACCGTGCACGAGGCGGTGCGCCTCTACGAGTCGTATGTCGTCGAACCGGCCAGGACCACCGAAGCCGGGCTCCAACGGGTGTGGCGGTTGGCCGAACTCTGGTTCGACTACTCCCGATCCCGGGTCTTCCCCGGTGGCTGCTTCTTCTTCGGGGTGTCGGCCGAGGTCGACGCCAGGCCGGGCCCGGTGCGCGATGCTGTCGGCGCCGCGCGGTCGGCCTGGGTCGGCTACCTCGCCCATCAGTTGGAGTTGGGGCGTCGCGCGGGCACGCTGCGCCCCGAGGTCGACATCGATCAGACGGTCTTCGAGATCACCGCATTCCTGGAGGCGTCCAACGGCGCCTCTCTGCTGCACGATGACGACGTCGCCTACGACAGGGCGGCCAAGGCGGTACTCCGGGTGCTGCGGGAGGCGAGTGCACATCCGGACCGGTTGCCGCTCGCGCCACGCTGACCGATGACGACGTCACCGTGCGCGGACCTGATCCTCTTCGGCAGGCTTGGTGATTCCTCCCGGGGCCCGCGTGAGGAAATCCATGATCGTGCGAACGGTCGTCGGGTCGGCGACGATGCGGGAGTGGCCGAGCCCCCTACTGGTGACCAGCCGGGCGCGGTCGCCGAACGTGGTGGCCATCCGCAGCGAATGCTCGGGCGGGGTTCGCTGGTCATCGTCATCGTGTAGGAAGAGCAGCTCGCCGGGAACGGACTCGGGGCGATGCCAGACCTGGAACTTCTCCCAGACGTCGACGAGTTCCGGGAAGAGTCGCTTCTCGATGTGGGTTCGGATCCGCGCGGTCACCTCGGGCCGTAGCGACAGCATCCGACCGAATTCGGCGACCAGATAGTCGAAGTCGCCGACGCCGGAGATCCCGACGATGCGATCGGCTCGTACGCCCGCTCGGAGGGCGTAGAAGGAGCAGAGCACGCCGAATGAGTGGCCGACGACCGCTTCGAAGTCGCCGTATCGCCGATGTAGTGCCGCGATGATCTCGTGGTATTCGACCACCGTCGTGGTGTTGCCTTCCGAGTCACCATGGCCGGGGGCGTCGAAGGCGATCGCGCTGCGCCCGGTGGCCTGTAGCTCGTCGATGAGACCGGCGAAGCGGGATGCGCGGGACTGCCAGCCGTGCACGAGCAGCACGGGACGGTCGCCGGTTCCCCAGCGGTAGAGGCGGACCTCTCGGCCGGCCACGGTCATCCGGTCGACCTCGGCCGCCTGATGGACCGGCAGCTCGGCGGGACGCACCTTCCCGCGTGGCGGGACGCGGCGGAACAACTCGAAGGCCAGGCGACCAGCCAGATCGGGGGCGATCGCAGACGTCGCGGACAGGGCACCACGGACGAGGGCGAAGAGGGGCGACATGACTCTCCTTCGGATCTTTCCGAGTCCGGGTTGGACCGGGCGACACCGGCTCGCGCCACCGAGCTGGGGAGCCGACATCGATAAATTAGCACGGTCGTTCGGTCATATTTCTGGCTTGCGGAGTGCAATCTGACGCGGCGACCCCGTGGCCGTCGTTCTCTCCAGGCTGGCTCGCGGGGTTGGCGGAGATCCGGCCGTGTCCCACTCGATCGTGGGAAATTCATCCATCGGTCGGGTGAGGGCTTCGGTGTGTCGGGCGATCTTGTGTCGGCGACTGCGGAAGATCAGCGGGTCATCCAGCCGGAACAGGGTTTTCAAGGGAGTCGAACAATGCGGATGCCGCGAACGCTGGGCGCCGTGCTCGCCGCAGTGGTCATGTTCACTGCTGCATTGGCGGGTGCGGGCAGTGCGGTAGCGGGTCCGCAGTCCGCCCCGAGGATCGTCGGTGGCACCCAGTCCGTCGAGAAGTACTCGTTCATGGCCTCGATCCAGCGAAAGTCCGAAGGTCGCGACCACTGGTGTGGCGGCGCGCTGGTCGACCCGATCTGGGTGGTCACCACGGCACACTGCCTGCAGGGCGACCTCGACGCGTACACCGTCCGAGTCGGTTCCAACGACCGGACGGCGGGCGGCGAGTACCGACGGGTGGTGGAGATGATCGCGCACCCGAACTGGGACGGGTTGCACGGCGATATCGCCATGTTGCGCTTGGAACGCGCGGTCACCGCCGCGCCGGTCGCCATCGCCAAGTCCTCGCCGATCTACGGCGATCCCATCCGCCTGCTCGGTTGGGGCAAGACCTGCAACACCTACGAGTGCTCTTGGGAGTACCCGAAGCTGCTGCGTGAGATCGACCGGGACGTCGCCTTCGACAACGAGTGTTCGCGAGCCACGATCGACGGACGCACCGAGTTGTGTGTGGACGTGACCAGCAAGGCCACCTCCTGCTACGGCGACTCCGGTGGTCCCGCGGTGGAGCGGATGCTCGCAGGCGGCTGGGGCCTGGTGGGGCTGGACGGACGAGGTGGCGACTCGGTGTGTGGCGAACGCGGCCTGATCTACACCGACGTGACGGCATACCAGGATTGGATCCGCAGTACAGTCGCGTGAGCCTCGACGCCGCTCCAGTGCGCGCCGCTTCGTCTGCGGCCCGTCGCCCTGAGAGCGGCGTCATATTTTATTGAGTTGAATTCCGGACTCTGTCGAGTGGATGCTTGTGTCGTACAACTAGTTGGATGACGCAAGCAACAGGAGAGTCCATGGACGCCGCTGCCGCCTCCCGGCCGGAGGCTCTCGAAGCCAAGGCTGTCGAGGTGGAGGCCGTCGGGCAGGCCATCGCCCGCGTGGTTCGGATGTCCAACTGCGCGACGGCTCATGCAGGCCGACTCGGAGTGCCGTCAGGGTGGGAGAAGGCGACCTATCTGGTGCTCTTCCATCTCGAGGCGGGCGCCCGACGCTCGGGCTCGGTCGCCGAGGCCCTGCACCTCGATCCATCCACGATCAGCAGGCAGGTCGCCACGCTGGTTAAATCCGGATTGGTCGAGCGGACGATCGACCCCGAGGACGGCCGTGCCAGCCTTCTGTCGATCACCGAGCAGGGGCGATCGATACTCGCCGCGCATCGGGCCACCCGTCGAGAACTCATCGACCGGATGATCACGGACTGGCCATCGCGGGACCGGCAGGACCTGGCTCGCCTGTTAACCCGACTAGCGGACGCTTTGGAGACCAAGCTCCCCGCCTACGTCGCGGACGTCATCCAGGCTCGTCATGAAGGGGAATCCTGATGTCAGAGGCGCTGGCCCCACCGGGGCAGGTAGCCAAGTCCGGTGACGGGGGGCTGAGTCACCGGCAGATTCTCACCGTGCTCTCCGGCCTGATGATGGGTATGTTCCTGGCCGCTCTGGACCAGACCATCGTCGCGTCGGCCATGCGCGTCATCGCCGACGAGCTGCATGGACAGACCGCCCAGGCCTGGGCGACCACCGCCTACCTGATCACGGCGACGATCACGACGCCGCTCTACGGCAAGTTGTCCGACATCTACGGGCGAAAGCCGCTCTATCTGACCGCCATCGGCTTGTTCCTCGTCGGCTCCGTGCTCTGCGGAATCGCGGGATCGATCTACGAACTCGCCGCCTACCGAGCCATTCAGGGACTCGGTGCGGGCGGATTGATGTCGCTGGCGATGACGATCATCGCCGATATGGTCGCGCCGAGGCAGCGGGCGCGCTACCAGGGCTACATCCTGGCCGTCTTCGGTGTCTCCAGCGTGCTCGGCCCGGTCGTGGGCGGCTTCTTCGCAGGCCAGGAGAGCCTGCTGGGTGTCGCTGGTTGGCGGTGGGTGTTCCTGGTGAACGTGCCGGTGGCCCTCATCGCGTTGGTCGTGGTGGCCAAGGTGCTCAACCTGCCGCACAACCGGGTCAACCATCGGGTCGACTACTGGGGCGCCGCCGCCCTGGTGCTGGCGCTGGTCCCGCTGTTGATCGTGGCCGAGCAGGGGCGCGAATGGGGCTGGGGTGCGGGCATCTCGATGCTCATGTACGCGATCGGTGCCGTCGGCGTCGTGCTGTTCGTGCTGGTGGAACGGCGGATGGGCGACGAGGCACTGTTGCCGCCGAGGTTGTTCCGCAGCGGAACCTTCCGTCTCGGCAACCTGATGAGCTTCATCATCGGCCTGGGGATGTTCGGCGGCATGGTCTCGTTGCCGCTGTATCTGCAGATCGTCAAGAGCCAGTCCCCGACCCAGGCCGGGTTGCTGATGCTCCCGCTGACCTTCGGCATCATGACCACGACGTTCGTCGTCGGCAAACTGATCGCCAAGACCGGGCGGATCAAGGTTTTCCCGGTGCTCGGCGCGGGGGTGATGGCGGCGGCGCTGTTCCTCTTCAGCACCATCGACGCCGACACACCGATGGTGCTGCTCGGCGCGCTGATGGTGTTGTTCGGTAGCGGACTGGGCCTGTCGATGCAGACCGTGACCCTATTGGTGCAGAACGATGCGCCACCGGCCGACAACGGGTCCGCGACCGCCGCCGTGACCTTCTTCCGGCAGACCGGTGGCACGGCAGGCACCGCGGTGTTCCTGTCCATCCTGTTCTCGGTGTTGGCCGGGCGGATCGCCGACGCGTTCACCTCGGCCGCCGACGACCCGGCGTTCAACGCGGCACTGCAGGACCCGGCGGTGCTGGCCGACCCGGCCAACCAGGGATTCCTGGAGAATCTCCAGGGCAGCGGATCCGAGCTGGACCTGAACGACACCTCGTTCTTGACCACCATCGATCCACGGTTGGCGGCTCCGGTGCTCGACGGGTTCGCGAGCGCGATGAGCACCGTCTTCCTCGTGGGTGGACTGGTGATGCTCGTGGCATTCCTGCTCAGCTGGTTCGTTCCGGATGTCGAACTCGGCAACCAGTCCGGCATCCAGCGGATGCAGGCGGAACGGGCGGCAGCGGATCGTGCCGCTGACTCCGAGTCATCGGCGACCCGGCATGCGGACTCGGTGCATGCCGAGGACGCGGGCGACCCAGAGGGGGCGGTCGAAAGACCGAGGGCGTCGACTATCGGCGCAAGCGGTTCCGGTGACCGCAGTCCGGACGATGCCTGAGGCCATCGGCGTACGAACTCCGGACGTGACCGGGCGAAGGCGGTCTCCGAGCGACTCGGGGGCCGCCTTCGCCCGGTCTCGAACTCAGACCTTGGGCGACTCGTGCTTGCCCTCGTAGTACCCGGTGTCGATCGCACGCTGGTAGGAGCGCTCGATCTCGATCTGGGCGTCGGTACGGCCGACCCAGGTCGCGCCTTCGACGCTCTTACCGGGCTCCAGCTCCTTGTAGACGCTGAAGAAGTGCTGGATCTCCATCCGGTAGAACTCAGCCAGATGGTGGATATCGCGCAGGTGCTCCGACCTGGGATCCTCAGCTGGTACGCACAGGACCTTGTCGTCGCCACCCTTCTCGTCGCGCATTCGGAACATGCCGATGGCTCGAGCCCGGATCAAGCAGCCGGGGAACGTAGGCTCTTGGACGATCACCATCGCGTCGAGCGGGTCGCCGTCCTCGCCGAGCGTGTGTTCGATGAAGCCGTAGTCGGCGGGATACTGGGTCGCGGTGAAGAGCGTCCGATCGAGGCGGATTCGTCCGGTCTCGTGGTCCATCTCGTACTTGTTCCGCTCCCCTTTGGGGATCTCGATGGTGACGTCGAACTCCACGCGGTGCCTCGCAATGTCTTCGCCGGGTTGTCTGGACGTTGTGTGATCCACAGTTTGCACTTGCGGTCACCCCAGGCCCTTAGTCTGAACGACGAGACCCGGCGGAGTCGCATCGAGAGCCCCCGTCGGCATGTGAAATCCATCCCCATCCGCGCCGCCGCCACATCCAACAGGCCGTTCTAGGAGGTCGCGTGTCCGATTCCGGGCACCCCCCGCAAGGGTCAGCCGCGCCCCGGCGCAACGAACCGCAGGGTTCGTCGGACCAGGATCGGGCGTCGAGCAACCCTCCGCCACCGCCTCCGGAGCATCGCTCAGGACAGGGTGCGTCGATGCCTACGGGCGATCCGGCCCGGCAGCCTGCGCAGCCCAAGGCCGAACCGGCGGGTCAGCGCGACCAAGTCAGGCGGGACAGCGGGCCCGATGGCTCGGAGACCCCGCGCTCGGCGACCGGGCTGCGGGGTGCCCTGTCCGGCAGCCTCACCGCTTCAGAAGGCAGCAGGCCGCCGGATTCGATGCGCCCCGCGCCTGCGTCGGCACAGCGACCGGGTCCGGGACAGCAGGGCCAGCAGCGGTACCCGCAGCAGAACCTTCAGCAGCCGCCGTCTCAACAGCGGCAGCAGCATCAGCCACCACAGCAGCAATGGCCGCAACAGGGCGCGTCGGGACCAGGTTCGCGCCCGCAGCCGCCCGCCGCGAATCGCCCGCCAGCCAATTGGGCGCCGCAGGATCGGCCGAGTCAGCAGTCGATGGGCGTTCCGCCGAGGATCTCGTCCGGAACGATCAGCTCGACCGTGGGCGGCGGGTCGATGACCCAGAACGAACCGGCCGCCACCACCGGCGACCAGGAGACCGTGGCGCTCACCCGGCCACCCACCGCCTTGTCCGGAGACCTCTCGCCGCGTTCCAGCGGCACGGTCTTCGAATCCGCCGAACCACCGGCCGCCGCATCCGGTGGTGAACCGCCCGAGGACCCGCCGTCTGCTCCGAAGGCAGCCAAGCCGCCACGCAAGCGGCGTGGATTGCTCATCGGTGCGTTGGCGGTCGTCGTGGTGGTCGCGCTCGGTGCCACCGCCGTCTTCACCATCGAACCCGTCGGCCGGGTCTTCGGTATCGGACCCTCCGCCGTGCCCACGGAGCCCGCTCCGGACCCGATCGATCCTGACTTCGCACTCATCCCGGTGGACCACGTCTCGGCGGGCCCGACCGAAGCCGGGCTGGCCTCGGCACTGCAACCCTCGGTGACCGCGGCGGAGGTCGGCACGCTGCACGCCGTCATCGTCGACCCGGGCACCGGACAGTCCTTGTGGGGCAACGAGGCCGACGTGCCCGCGACCCCGGCATCGACCACGAAGATCCTCACCTCGGCGGCTGCACTGCTGACGTTCCCCGCCGACCACACCTTCACCACCACGGTCGTCGCCGGTCCCACACCCGGCTCGGTGATCCTGGTGGGCGGCGGCGATCCCTCACTGACGGCCGTCCCCGAAGGGACGGACACCCTCTACGCATCCAACCCGGCCCGGATCTCCGATCTCGCCGCACAGGTGCGCGAGAACGCGGGTGACATCGCCATCACCGAGGTGCTGGTGGACGCGAGCCGTTACACCGGTCAGGCCATCGCGGACGGGTGGGATGCCAGCGATGCCCCATCGAGCTACGGCGGATTCATCGAGCCGCTGATGCTGGACGGCGGCCGGTCCGACCCGCTCAACGACCTCTCGCAGCGAGTCGGCGATCCTGCGTTGGAGGCGGGCAACGCCCTGGCCGCAGAACTCGGTGCGACCAGCGTCTCCGCCGTCGACGAGGCAGGCAGCCCGGCGGACGGCGAGGTGCTTGGCGAGATCAGCTCGCTGCCGTTGGTCGATCTGATCGAGGCCATGATGCTGCTCTCGGACAACGTCGCCGCCGAGATGCTGGCCAGGGAGGTCGCCATCGAGCGCGGCGCGGAACCGTCCTTCGCGGGCGGCGCCGCCTCGATCATCGAGGTCCTCGGTGAGAACGGCTTCGACATCTCGCAGCTGGAGCTCTCCGATGCCAGCGGCCTGAGCAACCAGAACCTCATCACGCCGAACCTGCTGGGGGATGTGCTCTCCCTCGCCGCCCATCCGGCGGACGAGTCGGACACCGCCGTCTCCCAACAGCTGCGGCCGATGCTCACCGGCCTGGCGGTGGCCGGGGCCAGTGGGAAACTCACCGATCGCTATCCGGCGGGCGCCTCTGCGGGGCGCGGTTGGGTGCGGGCCAAAACCGGCAGTCTTACCGCGGTGAACGGCCTGGCAGGAGTGGTCACCGACCGGGACGGGAAGCTGATGGCGTTCGCGCTGTTGTCGAGCGGAACGAACGCCACGGTGGCTCGCCCAGCGCTGGACGAGGTCACCAGCGCGCTGCGCGAGTGCGGATGTCGGTAGCCCCCGTCGTTCGGTAGCGTCGGCGGTGTGAAGCCCGACTCGAGCGTGCAGGAGCTGGAAGCGACAGCAGACCGAGTCCCGATCGCGTGGAGCGTGGCGGCGTCGACCGCGCAACGGCTGATGCGACCGGGACCGGTACTGCCGCTGGCGGAGGCCGAGGCCACCGTGGCCAGGCTGCGCGACTTCAGCGTGAGCGCCGAGGCGCACGTGCGTGAGGTCACCGGTCTCGGCGCCGGCCTCCCGCTGTACAGCGGGGAGGTCGTCGACCGGCCGGGTTGGGCGCAGGCGGCAGTTGTCGGCCTGGCCGCGTTGATGGATGACGCACTGGCCGGTGACGACCCGTCGACCCTGCTCGGCGGCGTCGCCGCAGGCAGCGCGGGCGTGCAGACGGGTGTGGTGCTCGCCTACCTCGGGAGCCGGGTCCTCGGCCAGTACGACCCCTTCGGCGGCGAGGATGGCTCGGGTCACCTGTTGTTGGTGGCGCCGAACGTGGTCGCCGCCCGTCAGGCCCTCGATGTGCCAGCCGAGGATTTCGAGATGTGGGTCTGCCTGCATGAGGCGACCCACCGGCTGCAGTTCAACGCCGTTCCCTGGTTGCGTGATCATTTCGCAAGCGAGGTCGGCAGTCTGCTCAGCTCGATGGACGACACCCTCGCCCAGGTGGTCGTCCGGCTGCCGGAGCTGGTCCGCTCCGCGCGGCGCCGTGGCGCCGAGGGTGAGCCGGTCGGGTTGATGGAACTACTGCAGTCTCCGGAACAACGCGTCCGCCTCGATCGGCTGATCGCGCTCTCCACGCTTCTGGAGGGCCACGCCGATCACGTGATGGATGCGGCGGGCCCGTCCGTGGTGCCATCGGTACGCCGAATCCGGGCCAGGTTCACCGCTCGCCGACGCGGTGGCGGTGTACTGGATCGGGTGCTGCGGTCGGTGCTCGGGGTCGAGGCGAAGGTGCGCCAGTACGCCGATGGCGCGCAGTTCACCGAACAGGTCGTCGATGCCGTGGGCATGGCGGGTTTCAACGAGGTCTGGCGTTCTCCCGAGACCCTGCCCAGCCGTGCCGAGATCAGCCGACCATCGGACTGGCTGGACCGGGTCCACGGTTAGGGCGACCCCCGGTGCGCGGGTCGGGTTCGACACCGCGCACCGTGTGGTTCTGCATCGGTGCCCGGCTGCGGGCCCTTATCGGGCATTCGAGTGTCCGGTAAGAGCTTCATCCGTATATGCGACAAGAATCACGGCCTTATCCGCTGATCTGTGGGTATGCCGGTGAATAATCTGCTTCGACGGCTGATTTTCGGGAAAGCGGTCGAGGCCTGGCTGCGTTGCTAGCAGAGCACGATGTCCGTGCGAGCTACGGCCGACGTGACATGGGATTTCCGAAGCTGCCGAATGGAATGCGCAGTCTGCCGAGAGACCGGACCTGATCGACGAGTCACCGCAGAACAGCCGATCGTGAATCGGCCGAATGCAATCGAGAAGAGTCGATGAAGGGCCCGACCTCGGGGATGCGGCTTCAATTGCCGTCGTGAGGCCGGACGCAGGGCTTATCAAGCGTGCAGGAAGCGTTACGTGGATATTCGCCGTTTGGCATGTGGACTCGGTAGGGCGAGCACGCTGGCCGACCTTGGACCATGAATTGCCTTTCCCGAGCCGGCTCGCAGGCTGGCACCGAAACGCGACGGCCCTCGCCTGCCCGTTGTCGGGCGCGAACCGGGATAGTCACGCCCTATGACCGCGTTGCCGCCCGCCGAACCCGCTATCGAACCCGGTGTCGCCCTCGACGAGGTGCGCGCTGCGGTGCGCAGGCTGCTGACCGGACCGGCGGCCGAGACTCTCGATCGGGTCGGCAGCATCGCGGTGGCCTGTTCGGGCGGCGCTGACTCGCTCGCGCTGGCGGGCGGCCTCGTCCAAGCCGCCCGCAGGCCCGGCCTAGCTGTGCACGGACTGGTAGTCGATCACGGTCTGCAACCGGACTCGGCCGCCGTCGCCGCTACCGCCGCCGATCAACTCGATGCCCTCGGGTGCGCGCGGGTCCGGGTGCTCGGCGTCACGGTCGCGGGCGACGGTGGCTTGGAGGCGGCGGCGCGGCGGGCCCGATACGACGCGCTGTCCACAGCACGGGAGCACCCCGAGCAACTCGTCCTGCTCGGTCATACCCGCGACGACCAGGCCGAGACCGTGTTGCTCGGCCTTGGCCGGGGATCGGGCCCGCGTTCGATCGCAGGCATGCGTCCACTGGATCCGCCCTGGGCTCGGCCACTGCTGGAGTGCACCCGAGCCACCACGGAGGCGGCCTGTGTCGCCCTCGGGGTGACGCCGTGGCGGGATCCGCACAACAGCGCGCGCCGATTCACCAGGGCTCGGCTCCGACACGAGGTGTTGCCGCTGTTGGAGGACGTGTTGCAGGGCGGGGTGGCCTCGGCGCTGGCCAGGACTGCCGAGCAGTTGCGGGCCGATCTGTCCGCGCTCGACGAGTGGTCGGATCGAGCGTTGGCGGCCGCGCGTGACGAGTCTCACCCCGACGAGTTGCGGGCCGGGTATCTGGCCGATCTGCCCGCCGCCATTCGGTCCAGGGTGCTCCGTTCCTGGCTACGGGCGATGGGTGTCCGAGACCTGTCCTCCCGGCATCTCCAGGCCGTCGACGAGTTGGCCTCCCGATGGCGCGGACAGGGCGGTGTGTGGCTGCCGGGTGGGTTGGTGGCCGCGCGGGCGCATGGCAGGCTTGCGCTCCAGGCGCCGGACTGACTTCGACGCAGGGCGATCGACTGGGTCACCGGCCGGAACGCACCAGCCGAATAGAGAGGGGAAGCCGAGCCGTGTACGACGGCGACATCGCTTCCGTGCTGATCAGCGAGCAGCAGATCAGGGACAAGGTCACCGAATTGGCTGCCGAGGTCGCGGCCGCTTACCAAGAAGCGGAATCCGATCTCCTCTTGGTGGGCGTTCTCAAGGGTGCGGTGATGTTCATGACCGACCTGGCCCGTGAGCTGCCGATCCCCACCCAGCTCGAGTTCATGGCGGTGAGTTCCTATGGGTCGGGAACCTCGTCGTCCGGGGTGGTACGCATTCTCAAGGACCTCGACCGGGACATCGCGGGCCGCGACGTGCTGATCGTCGAGGACGTCATCGACTCCGGGCTCACCCTGTCGTGGCTGCTGAAGAACCTCGCCTCGCGTAACCCGAAGTCGTTGGAGGTGTGCACGCTGCTGCGCAAGCCCGACGCCGTTCAGGTGGACGTCCCCGTGCGCTTCGTCGGTTACGACATCCCCAACGAGTTCGTCGTCGGTTACGGCTTGGACTACGCCGAGCGGTACCGGGATCTGCCCTACGTCGGCACCCTCGAACCCCGGGTCTACTCGAGCTGATTCAGCCGGCATCGGGACGATCGTCCCGGCCGATTCGATCTCGATCTCCCATCCGCCGGATGTGACCTCAACCGCTCATCCGGCGGATGTCGGGAACTTCTTCGGCCGCCGGGCAGTTGAGTCACCGTGAGTGAGCAGCGTGCGGGGTATCGGCCGGTACGGCCGCCCCACCGCTCGGCGCAGTACGCAGCGCGTTGAGCGGTACGCTGGTCGGAACTGGGTTCCCGTCTCGTCGACGGATTGCCCGCACCGTGCGTCTCTGGAGGGTCGAGGCCGAAAGGCGGCCGTAGCCGAATGGACCGTAAGCGCCTGCTCCGTAACCCGCTGCTCTGGATCATGGCAGTGCTACTGCTGTGGCTGGGGTTCAGCGCCCTGTTCGATGACACCCGTGGGTACGAGCAGGTGCCGACATCCACGGCTCTGGAACAGATCACGAACGGCAATGTCCGCGAGGCCGTGCTGGAGGACCGTGAGCAGCAGCTCCGGTTGACGCTGGAGAACCCGGTGAACGGGAACAACCAGCTCATCACCCAGTTCCCCTCGCAGGCCACCGATGAATTCACTCAGGCGCTCATCGACGCCGATATTCCCGGTGACTGGGACACCACCGTCACCCAGGACTCCCTGCTTTTCCAGGTTCTGATCTACCTCATCCCGCTGGGCCTGCTCCTGCTGCTGCTCATGTGGATGATGAACAATGCTCAGGGCGGTGGAAACCGCGTCATGAATTTCGGCAAGTCCAAGGCCAAACAGCTCAACAAGGACATGCCGCAGACCAGTTTCTCCGACGTGGCGGGCGCTCAGGAAGCGGTCGACGAGCTGTACGAGATCAAGGACTTCCTGCAGGCACCGGGCCGCTACCAGGCACTCGGCGCGAAGATCCCGAAGGGCGTCCTGCTCTACGGCCCGCCCGGCACCGGTAAGACGCTGCTGGCGCGTGCGGTCGCGGGCGAGGCGGGCGTGCCCTTCTACTCGATCTCCGGTTCCGACTTCGTCGAGATGTTCGTCGGTGTCGGTGCCTCCCGGGTTCGCGACCTGTTCGAACAGGCCAAGCAGAACGCGCCCTGCATCATCTTCGTGGATGAGATCGACGCGGTCGGCCGTCAGCGTGGCGCCGGACTCGGCGGCGGACACGATGAGCGGGAACAGACCCTCAACCAGCTGCTCGTCGAGATGGACGGCTTCGACTCGCGTGGCGGCATCATCCTGATCGCCGCCACCAACCGGCCGGACATCCTCGACCCCGCGTTGCTGCGTCCCGGCCGATTCGACCGCCAGATCCCCGTAGCGGCACCCGACATGTCGGGCCGTAAGGCGATCCTGCAGGTGCACGCGAAGGGCAAGCCGTTCGCTCCCGATGTCGACCTGGTCTCGCTGGCCAAGCGCACCGTGGGTATGTCCGGCGCCGACCTGGCCAACGTGATCAACGAGGCCGCGCTGCTCACCGCACGCCAGAACGAGCAGCTCATCACTGGTGCCTCGCTGGAGGAGTCCGTCGACCGGGTCATCGGTGGGCCCGCCCGCCGGAGCCGCGTCGTCTCCGAGAAGGAGAAGAAGCTCGTCGCCTACCACGAGGGCGGTCACGCGCTCGCGGCGTGGGCGATGCCCGACCTGGAGCCGGTCTACAAGCTCACGATTCTGCCGCGAGGCCGCACCGGTGGTCACGCCCTGGTCGTCCCGGAGGACGACAAGGAGCTGATGACCCGCTCGGAGATGATCGGCCGGTTGGTGTTCGCACTCGGCGGTCGTTCGGCCGAGGAGTTGGTCTTCCACGAGCCCACCACGGGCGCGTCCTCCGACATCGACCAGGCGACGAAGATCGCCAGGGCGATGGTCACCGAGTACGGCATGAGCGCGCGACTCGGCGCGGTGAAGTACGGCAAGGACGAGGGCGACCCCTTCCTCGGTCGTTCGATGGGCAGCCAGCCCAACTACTCGTTGGAAGCGGCCCACGAGATCGACAAGGAGGTGCGCGCGCTCATCGAGGCGGCGCACACCGAGGCGTGGGAGATCCTGCGGACCTACCGGGACATCCTCGACGACCTGGTGCGGGAGCTGCTCGAGAAGGAGACGCTCCAGCGGCGCGACCTCGAGCGGATCTTCGCAGGCGTGGAGAAGCGGCCCCGGATCACCGCGTTCAACGACTTCGGTGGTCGCACCCCGTCGGACAAGCCGCCGATCAAGAGCCCCGGTGAGCTGGCCAAGGAGCGCGGCGAGCCGTGGCCGCCGATCGTCGAGTCCGAGCCGACCCCGGTCGGTGAGGCGCACGGCGGTGGCGATCTGCCCGACGGACCGCCCGGATCGCATGAGCCCGACGGATTGCCCGGCACGGGCCACGGGCCGGGCGAGGGTGTGCCCCCGCACGACCCGGAGCCGCGTACCTATCCTTCGACGGACACCGACCCGACTGTTCGCAGGCCCGTTCCGCAGGGTGTCGGCCCGCAGGGCGTGAATCACAATGGCGTGGGTTCTGGCCCGCCGAACTACGGTGCGCCGCCCGGATGGACCCCTGCGACGTCGCCCACCGGACCGCCGAGTTCGTGGACCCCGTCGTGGGAGCGTCAGTCCGGCCCGTCGTGGGAACGTCGTGACGAGGCAGGCGCTGTCTCGGGTGTGAACCCGACACACGATGGGACGGAACGGATCAACCGGGATGATTTGAGGCCGGACCGTCCGGTCGACGACGAGGACCAGTCAGACGGTGGTGGTCGCTGACCCCGCCGTCAGCGGAGGAACGCGATGACCGACCTGATCAATGAGAACGGCCAGGCCGAGGCGGGGGCGAGACCCTCGTCTCGGCCCGCGTTCGACCAGCCCCGCGCCGAGGCAGCGGTACGCGAGCTGCTGTTGGCCTGCGGAGAGGACCCGGATCGGGAGGGCCTTCGGGACACTCCCGCCCGGGTGGGTCGGGCATACCAGGAGATGTTCGCCGGACTGTTCACCGATCCGGACGAGGTCCTGGACAAGACCTTCGACGAGGGTCACGACGAGATGGTGCTCGTCACCGACATCCCGATCTACAGCTACTGCGAACACCACCTGCTGCCGTTCCACGGGTCCGCGCACGTCGGGTACATCCCGAACCAGCAGGGCCGGGTGACCGGGCTGTCGAAGCTGGCGCGCGTGGTCGATCTGTATGCCCGACGCCCGCAGGTGCAGGAGCGGTTGACCTCGCAGGTGGCCGATGCGCTGGTGCGCAAGCTCGACCCGCGTGGGGTGATCGTGGTGATCGAGGCAGAGCATCTGTGCATGTCGATGCGTGGCGTGCGTAAGCCCGGTGCACGGACCACGACGTCGGCCGTGCGTGGCCTGTTCCGCTCCTCCCCGTCGTCCCGCGCCGAGGCTCTCGACCTGATCCGGGGGCACTAGTCGTGCATCGGCTGCTGCCCGATCCCGGCCGATGCGCGGTGCTGGGCGTGCTCAACGTGACGCCGGACTCCTTCTCCGACGGCGGTCGGTACCTGGACCGGGACGAGGCGGTCGCGCACGGCGTTCGGATGTCCCGGCAGGGCGCCGACCTCATCGATGTCGGCGGCGAGTCGACTCGCCCCGGTTCCGATCGGGTGCCCGCCGAGGTCGAGCTGGACCGGGTCGTTCCGGTGATCCGCGAGCTGGTCGCCGAGGGCGTCCCGGTGAGCATCGACACGACGAGGTCGGTGGTCGCGGAGGCGGCGGTGGCCGCGGGTGCGACGGTGATCAACGATGTTTCCGGCGGGCTCGCCGACGATCGGATGGCCAAGGTCGTCGCCGATGCGGATGTGCCGTGGGTGTTGATGCATTGGCGCGGCCACAGCCGCGAGATGAACTCGCTGGCCGAGTACTCCGACGTGGTGACCGATGTGCGTACCGAACTGGCGGCCCGGGTGGATGCGGCCCTGGCCGCCGGGGTGGCTGCTTCGGCGTTGGTACTGGATCCCGGGCTGGGTTTTGCCAAGACCGCGGAGCACAACTGGCAGTTGCTCGGCCGGTTGGACGAGTTGAGCTCGCTCGGACTGCCGATCCTCATCGGCGCATCACGCAAGCGGTTCCTCGGTGCGGTGCTGGCCGACGATGACGGCAAGCCGCGTCCCGCCGCAGGTCGGGAGGTCGCGGGCGCGGTGATCTCGGCGTTGTCCGCGCAGGCAGGCGCCTGGGGCGTACGGGTGCACGACGTGGTCAACTCGCTGGACGCGGTGCGGGTGGCGGCTGCATGGAAAGGCGGGAACGACCGATGACCGATCGAATCGTGTTGACCGGTTTGAAGGTTCGCGGCAGGCACGGTGTCTTCGAGCATGAGCGCCGGGACGGCCAGGACTTCATCGTGGATGTCACGGTGTGGATCGACACCGATCGCGCGGCGCGCAGCGACGACGTGCAGGACACCCTCGACTACGGGGTGCTGGCCACTCGGATGGCCGAGATCGTCGGGGGCGAACCGAGGAACCTCATCGAGACCGTCGCCGCCGAGGCCGCCGATTCGGTGTTGTCCGATCCTCGGGTACACGCCGTCGAGGTGACGGTGCACAAGCCGCAGGCACCCATTCCGTTGGAGTTCGCCGACGTCGCGGTGACCGTGCGCCGGTCGCGGCGGGCGGGTCGGGGACGGGCCGACTGATGAGCCGCGCGGTGCTCTCGCTCGGTTCGAATCTCGGTGACCGCCTGGCCATGCTGCGCTTGGCCGTGACGGGGCTGGGCGAGGCGGTGCGCGCGGTGTCGCCGGTCTATGAGACCGCGCCGTGGGGTGTGTTGGATCAGCCGGATTTCCTCAATGCGGTGGTGATCGTCGAGGACGACATCGGGGCCTGGGACTGGCTTCGCCGCTCGCAGGCCTTGGAGACGCAGGCCCAGCGGGTCCGGGAGATCCGTTGGGGGCCACGCACCCTCGACGTCGATGTGGTGACGGTGGACGAGGTTCGCTCGGATGATCCCGAGTTGCTGCTTCCGCATCCCGGTGCGGGCGACCGAGCCAGTGTCCTGGTGCCGTGGCACGACATCGACCCGGATGCGGTGTTGCCGGGGCGCGGCCCGATTCGCGACCTGCTCGCTGGACTCGACAGCACGGATCTGCGCCGACTCGACACGGGACTGCTCGACGAGCACCCCACGACGAGGGGGAGCCGATGAAGTTCACCCGCGCACGCGATCTCGGTACGGCGGTGATCATCGCCGGGCTGTTGTTCAACCTGGTGGTGCAGGCGGGCTATGGGACGTGGCCGCCGTTGCCGTTGCTGGCGGGTAGCCCGCTGTTCGTCCTCGCGGTCGTCGAGGTCGTACTGGCCTTCTCACTGCGGTCGAGGATCGGGCGTCGTCCCGGTGCGCCGCCGGTGGAGCCGTTGGTGGCTGCCAGAGCGGTCGCGTTGGCCAAGGCCACGTCCTTGACGAGTGCCATCGTCCTCGGCGCCTGGCTGGGTGTGGTGGGCTATCTCATTCCGTTGATCGGCGATATCTCCGCCGCAGGTGCGGATATGGCCGCCGCCGTGGTGGGTGCGGTGTCGGCTGCGGCGGCGATCGCGGCCGGATTGTGGCTGGAGCACTGCTGTCGGACGCCCGAGGACGACGACGAGAAGCATCCCGATCGGCACGCCTGATCGGCTCCGCGCTGGTAGGGCGGGTTGATCTTCGTAGTGCCTGCGAGGAGGTCTCGCGAAGATAACCGGCAGGTACCGTATGGGCCATGGTCGGCTTGTCAGATACGGACGGCGAGCGTCATCGCATTGGCCGAGGAACCATCCTTTGGGCGTTGGGTGCGGGTCTCGCACTCATCGCCACGGTGGTCCTCGTACTCGGTGACGATGCGCGTCTGCTGCGGCTCGGCCTGCTTGCGGCGTTGTGGACGGCGCTGTTGGGCGCTTTCGCCGCCGCCAGATATCGCAAGGACGCCAATGCCCGCACCGGTGAAGCCGACCGGTTGCAGCAGATCTACGAACTCGAATTGGAACGCGAGATCGCGGCGCGTCGCGAGTACGAACTGGAGGTCGAGGCCGAGACCCGACGTCAGGTCGAGGAAGAGGTCCGCGACGAGTCGCGCCGGGAACTGGATGCGCTGCGCGGTGAACTTCGGAATCTGCGGGAGAACCTCGAGGCGCTGCTCGGTGGTGACGTGCTGGTCGAGCGCGTCGCCCTGCGCGCGGAGTCGACCCGGTTGCGCTCGCTGTCCGACCAGTCACGGGTGATCGCCGCGCACGATGACGAGATCCGCAGCATCACCTCGTCGAGCTCCTCCTCGGTGGTCTCCGCCGAGGAGACGCAGATCATCGACGCGTTGGTGGAGGTAGAGAACGCGGTTCAGGAGATGGAGCTGCGGTCCGGGGATGGACGCGGCATCGGTTCCCCGGGACGCAATCGGCCCGGCCGAGGCGACCGACCGCATCCGGTCGAACAGTGGCGGGCGGGCGCGCCACGCCGGGAAGACTCCGGGCGGACCGCGACCCGGCGTCCGGGACAACGTCCACCGGCACAGGTCCCGCCGCAGGCCAGGCCCGCCGCCGGGCACGACCGCCAAGAGGACCAGAGCTCGCGGTCGATGCGGATGGAGGTCGTCGGCGAGGTCGAGTCGCCCCAGCCGATGGATCAGCGGGATCAGCCGCCCGCTCGGCCGCGCAAACCGGCGCAGGCACCGCCACCACCGCAGAAGCAGCCGCCGGCCCGGGGGCCGAACCGGCCGCCCGCCCGCCGGAACCCGCCGCAGCCTCCCGAGCAGCCCACGCGCCAGGCGCCGCCACCTGCGCCGAAGCGGCCGACCCGGGAGGAACCCACCCGGCAGATCAACCGTCCGAAGCGGCCCGCACCCGCTGCGCCGCCGCCTGCCCCCGTGCCCGCGCCGGTATCGCGGGCGACGGAGGAGACCGCCTTCGACGGCATCGATGGTTGGCAGCCCGAGATCGAGCAGCCGGTGGCGGTGGAACCCGAGCCGACCGGTCGTCGGGCGGCCCGTGGTCGTCGGGCGGCGCCGGAGGACGGCGATGACGCGGGTGCGCACGCTTCCGGCCGTTCGGTGAGCGAGCTGCTGGCGGCCTACAGCGACGAGCAGCCCCGCAGGCATCGCCGCAGGCGCGACTGATCACCCCGAGGCGGGGCCGCCTTGGCATCGTCTTCGCTGCCCGCGCTCCGGCGATGAACGCGGGGCGCTGAGTCATGTCGCGTGCTGGTGCGTCCCCGCTGACTGTCTGACGGCGGCGATGGGCGGTCGGGTCGACCGTCCGGCGGCCATGTCGGTGACCCCGAACCCTCCCGAGTGAATACGGTCGGTGGTCATCCGAGCCGAATGGGCTGTTCACCTCGACAAACGGTGCTGATCGCCGGCCTGGATGGTCAACACGATCGATAATGAGAGGGCGGGGTCTGCCCCCGTGCGGGGGCCGGTACCGGTGCCGGGGAGGGGCCCGCGGCGTCAGGGGAGGCCCGATGTCAGACCGTGGCTCGCGTGCGACTTTCCCGATGAAATACGAGGAGCTAGCCGGGCCCGATGTCGTGGTCGACCCCGCCGACCGGCGCTCTTCGGCGCGCCGGATTCCGGTGCAGGCCCGGCGATCGGCGGCTGCGGGCAATGCCCTGCCGTTCGGGTCACCGCCTCGGTCGCTACGTGCTGCGGCCGTGCTGCTCGCGGTGTTGGCCGCCGCGATGCTGCTGGCCACCTTCGTCGTGGCGTTCTGGCTGTGGCAGGGCGAGCTGGTGGCCACGCCGCCTGCGGTGGTGTTCTTCTGCCTCTTCGCCCTGTTGCCGGTCTCGATCGTCTCACTGTTGTGGGCGGCGGCCCGCGCCGTCTGGCATGGCCGGAGCTGGGGCCTGAGTCTGGCGGCGGGTATCTGTGTGTTGTCGGTGATCGGCGCGGGTTTCCTGGTGGTCGACTTCGGCTATCGCTCGGTCGTCGGACTCACGATCGACGCCGCTTCCTGGTGGCTGTTGCTGGTGGTCGCTGCGGTGATGCTGTTGGGCTCCATCGCGGCGGTGCTACTGCGGCGGCTGCGGTACAACCCGTTCGTTCTCGCCGGTGGCATTCGAGGCATGGACGACGCCACGATGTCCAGCGAAGCGGGGGACTAGCCGCCAGCGACATCGGGCTGACGCATCGGGTCTCGACGGGCTCACTCGATCGGGAGCGCCCACCGCGTCACCCACGGGGGCGTTGTGGCATTCGGCGAACTACACCCGACCGGCGGTCACCCCGTTCTCGAACCGCTCGACTGAGTCCCCGAACTCCTAGTGTTACCAACCGTGACCAGCGAACATTCGTCGACGTCGCAGCGATTGACGAGCTCGCAGGCGAGCCGTTGGCAGCGTTTCCTGCTGCCGGTGCTCGGCGTCGTGATCCTGGGTCTGTGCGGGTTGACGCTGCTGGGCCTGACCCATGCTCGGGTGGGCGCGGTCGCGCTGGTGGTCGGCGCCGCGGCCGCGTTGTTGCCGCTGGGTCCGGTGATCGCGACCTTTCTGTGGGTTGACCGTTGGGAGCCGGAACCACCGAGGCTGCTGTTCGCCGCCTTCCTCTGGGGCGCCTGTGGCGCCACGATCGCCGCCTTGCTGATCAACGACACCGCGCAGGTCGTCGGGGAGGTGCTCCTGGGCACCGGCGGCGGTGACCTCGTCGCCGCGTTGATCTCCGCCCCGCTGTTCGAGGAGGCCGCCAAGGGGCTCTTCGTGCTCGCTGTGCTGCTGCGCCGCAGGCAGGAGTTCAACGGGATCGTGGACGGGATCGTCTACGCCGGGATCACCGGTGTCGGGTTCGCCTTCACCGAGAACATCACCTACTTCGGGCTGGCCTTCGTCCAGGGCGGCTTCGGTGACATGAGCGGCGGCGTGGTCGCGGTGTTCGTGCTGCGCGGGGTGCTGTCGCCGTTCACCCACTCGTTGTTCGGCGCGATGCTGGGCATCGGGCTCGGTATCGCCGCCTGCACCAGCCGTCCACGAATGCGGATCGCGGCGCCACTGATCGGTTACCTGATGGCGGTGTTGCTGCACGCGCTCTGGAACGGGGCTGCGACCCTCGGCGGCGGCCGGATCTTCATCAACGTCTACTTCCTGGTGATGGTGCCGATCTTCCTCTCCACGGCGCTGCTGGTCTGCTGGCAGCGTCGGCGTGAACAACACGTCGTGGTCACCCAGCTGCCCGGCTTCGCGGCCGAGGGGTGGATCGCCGCCAGCGAGATCGGCCTGCTGGCCAGCCTCACCAGCCGCAAGGAATGGCGGGTCGCCGTCCGCAAACGGTCCGGGGCCTCGGCAGGCAAGGCGGTGGCGGCCTACCAGCTCGCGGTCACCGAGCTGGCGTTCGTGCGGAATCAGTTGGCAGGCGGCCGGACGTTCCCCGAGACGGCCGAGCGACTCGACCAGGCGGTCGCGCGGTTGATCCGGAGTAGAGCGGCCGTCCTGCGCTCGCCAGGCGCCCTGGCGGACGCCGCGCGCAGCACTGCGGGCATCCGTAGACGGAACCGGCCATCGCGCGGTTCCGGTTGGCTGTTCGACCGCCAACCCGTGCTGCTGCGAGCACTGGGCCCGCCTCGACGGCCGGTCTCCACCGAGGTCACGCTGCCCGGGATCGTGGTCGGATCGAATCGATCGGCCGATGAGACCCTGCCCATCCCGAAGATGGTCCTGGAGCCGCTGTCGAGCGGCGCACCGACCGTCCGCCACGACGGGGTCGTCGCTCCGGTCGAGCCTGCCCTGACCTCGGCGCGGGAACCGGTGATCCCGGCGCAGTCCTCGGAGTCGACCGACGTGACCGTGGTGATCGACCCGGTGCCGCCGACCAGCGGGGAACCGAAGGCCTGATCGGCTCGGGCGCCGGCGGCCGATCGCGGCGGTGAACCTGCTCACCCGATCGCGGCAGACCGGCGTCGATCCCGTTACGCTCGCCGCCGTCCGGTACCCGTAGGACGAAGGACGGGACTGGAACGGCAGAAATGGAGTCGCCACCGACATGATCGACAACGCAGGGGTTCGGCCTGCGAGATTGGCCGTCGGAGTCATCTCGGCAGGTCGGGTGGGTGCCGTGCTCGGTGCCTCGCTCGCCAGGGCCGGGCACGTCGTCGTCGCCACCTCCGCGGTGTCCGATGCCTCGTTGCGTCGGGCCGAGCAACTCCTTCCCGACGTCCCGGTGCTCGCGCCCGACGAGGTCGCCACGAGGGCCGACCTGGTGATGCTCGCGGTACCGGACGATGTGCTGCCCGGCATGGTTGCTGGGCTGGTCGCCACCGGGGCACTGCGAGCCGGCCAGATCGTGGCCCACACCTCGGGCGCCCACGGGGTAGACGTGTTGACCCCCGCCGCCGAGCTGGGCGCGCTCCCCCTAGCCCTGCACCCCGTGATGACCTTCACCGGTCGCAGCGAGGACCTGGAGCGACTCGCCGCCTGCTGCATCGGCGTCACCGCGTCCGGGGACCCGAATTCCCCGGTCGAGCCCGGCTGGAATGTCGGCGAAGCGCTGGTCGTCGAGATCGGCGCGGAACCGGTCCGCATCCCCGAGGCGGTCCGCCCGCTGTATCACGCGGCGCTGGCACACGGCGCGAATCACCTGATCACCCTGCTCACGGAATGCGTCGGGCTGCTCTCCCAAGCGGGCGTCGCGCATCCGGAACGGCTGTTGGGACCGCTGTGCGGCGCCGCGATGGACAACGCCCTACGCCACGGTGATCGAGCCCTGACCGGCCCGGTGGCCAGGGGCGATCTGAGCACCCTGCGCACCCATCTCGACGTGCTCGGCGAGGTGGCACCGGAGGTGGTCCCGAGCTACCGGGTGCTGGCCGCCCGCACCGCCGACCGAGCGAGAGCCGCCGGTCTGCTCTCGGACTCGACCGCCGCCGAGGTCGACGACCTGCTCAACGAGGAGCCCCGATGACCGAGACCCAGGCCACGCCCGGAGCGCCGGGGGAGTCCCCGTTGTTCGCGCCCGGTGATACGACGGTGCACTCCGACCCCGCGCAGCTGGCGAGGGTCACCAGGGCGCTGCGGGCCACCGGACGACGGATCGTCCTGGTGCCCACCATGGGGGCCCTGCATCGCGGGCACCGGGAGTTGATCCGCCGCGCCAAGCGGGTCCCCAACACCATCGTGGTGGTCTCGATCTTCGTCAACCCGCGTCAGTTCGGCGCAGGCGAGGACTTCGAGCGCTATCCCCGGGACCTCGACACCGACGTCGCCGTCTGCCGTGCGGAGCAGGTCGAGCTGGTCTTCGCTCCGACAGCGGCGGCGATGTACGGCGCAGGTACCTCGATCACGGTGTCGGCCGGCCCCCTCGGCGATGAGCTGGAGGGGGCGAGCAGGCCGGGGCACTTCGCGGGCGTCCTGACCGTGGTGGCCAAGCTGCTCAACATCGTCCGGCCGGATTTCGCCTTCTTCGGCGAGAAGGACTACCAGCAGTTGGTGCTGCTGCGTCGGATGGGGCGCGAGCTCGACTTCGACGCCTCGATCGTGGGCATCCCCACGATCCGCGAACACGACGGCCTGGCGCTGTCGTCCCGGAACGTCTATCTCGATGCCGAGGCACGCAACGCTGCGGTGGTGCTCTCGGCGGCCCTCACGGCAGGTGTGTATGCGGCTCGCTCGGGCGGGGATGCCGCGCGGGTGCTGGCCACCGCCCGCGAGGTACTCGACGGTGAGCCTGCTCTCGACGTGGACTACCTGGAGCTTCGCGACGTTGAACTGAATGCCGTCGACGAGCAGCGCGAGGCCCGGCTGCTGGTGGCGGCTCGGGTCGGCGCGGTTCGGCTCATCGACAACGTCGCGATCGCCTTCGGAACGGCCGAGGAGCAACCGGGCGAGGTCGCGGACGCCCCGGCTGCGGACGGTGCGGCGACCGACTCCGCCGAGAGTCGCTGAGAGGGAGAACGAGATGTTGCGGACGATGCTCAAGTCGAAGATCCACCGCGCGACCGTCACCCAGGCCGACCTGCACTACGTCGGTTCGGTCACGGTCGACGAGGACCTGATGGATGCGGCCGACCTCTTGGCCGGTGAGCAGGTCGCCATCGTCGACGTCACCAACGGTGCCCGGCTGGAGACCTATGTCATCCCGGGCGAGCGCGGCACCGGCGTCTTAGGGATCAACGGAGCGGCAGCGCACCTGGTGCACCCTGGTGACCTGGTGATCCTCATCGCCTATGGGCTGATGGACGCCGCCGAGATCCGCGAGCACCGCCCCTCGGTGGTGTTCGTCGACGCAGACAACAAGGTGATCAGCCTCGACGCCGATCCGGCAGTCGTTCCCGATGGCTTCGGTCTCTCATCGGGCTCCATCGATTCGCGGTCGGCCGATTCGGCCCCGACCGCAGGCGGCTCGACCACCGCCCGGTCCGAGAGCATCGCGGCGGGCGAGACCGATGATGCGGTGCGCCTGGACGCCTTGTTGCAGTCCGAACGCTGACGGCCTTCCCTGGCCGGCGGCCTGCGAAGGGAGAACCGGCGGTGCTGCTCACCATCGATGTCGGGAACACCAACATCGTGTTCGGCCTGTACGTCGGCTCCGGGCCGGACGCGCGGCTGCTGCGTGACTGGCGGATGCGCACCGATGCCCGGATGACCGCCGACGAACTCGCGTGGACTATGCGCGGTCTGCTCGGTGAGCATGCCGACCGGATCACCGGGATCTCCGCGTTGTCGACCGTGCCCGCCGTGGCGCGCGAACTGCGGGTGATGCTCGCTCGGTACTACGCCGAGGTCCCGACCCTGATCGTGGCGCCGGGGGTGCGGACCGGGGTCCCGCTGCTGGTCGACAATCCCAAGGAGGTCGGCGGGGACCGAGTCGTGAACACCCTGGCGGCCCACCATCTCTACGACACGGCCTGTGTCGTCGTCGACTTCGGGACCTCCACCAACATCGACGTGATCTCCCGGAAGGGCGAGTTTCTCGGCGGGGTGTTCGCGCCCGGCATCGAGATCTCGGTGGACGCCCTCGCTGCGCGGGCCGCTCAGCTGCGGAAGGTGGAGTTGCTGCGGCCGAGGAACGTGATCGGCAAGAACACGGTGGAGTGCCTGCAATCCGGCATCCTCTTCGGCTTCGCAGGCCAGGTCGACGGCCTGGTCCGCCGGATCCTCGCCGAGCTGTCGGCAGGGGAGCACGGGCCGGTCACCGTATTGGCCACCGGCGGACTGGCCCCGTTGGTGATCGGGGAATCGGAGACGATCACCACCCATGTTCCCGATCTCACGCTCATCGGCCTGCGTTTGGTCTACGAGCGCAATATGAGCTGACACCGGCCGCGCCGAGTCGGGGTCCGCAGTGGCCGCCGAGTCGCCCGTCGGCAGCCGTATCCCGTTTCCGCCGAGCGCCGGTCGGACCGTACGCTGTGTCGCTGTGAACGCGATTCCGGAACACGACGCCACGACCAGCGAGGACACTCTTCCCGAGCAGATGAAGGTACGCCGGGAGAAGCGCTCGAGGTTGCTGGAATCCGGTATCGAACCGTATCCGGTCGTGCTTCCCATCACACATACCGTCGCGGCGATTCGCGCGAAGCACACCGATCTCGAGCCCGACACCGCCACCGGCGAGATCGTCGGCATCTCGGGTCGAGTGATGTTCCTGCGAAACACCGGAAAGCTGTGCTTCGCGACGCTGCGTTCCGGAGATGGTTCCGAGTTGCAGGCGATGTTGAGCCTGGCGCAGATCGGGGCGGAGTCGCTGGCTTCGTGGAAGGCCGATGTCGACCTCGGCGATCACGTATTCGTGCATGGCGAGGTCATCACCTCGCGCCGGGGCGAGTTGTCGGTAATGGCCGATGAATGGCGGATCGCGGCGAAGGCACTGCGTCCGTTGCCGGTGACACACAAGGAACTGAGCGAGGAAACCCGGGTTCGCCAGCGGTACGTCGATCTGATCGTGCGGCCACAGGCCCGTCGGATCGTCGAGACTCGGGCCGCAGTGGTTCGTTCGCTGCGGGAGTCGTTCCATCGGCACGGCTTCACCGAGGTCGAGACGCCGATGTTGCAGACCCTGTACGGGGGCGCGGCGGCCCGACCGTTCCACACCCACTCCAATGCGTTCGACATCGACCTTTACCTGCGCATCGCGCCGGAGTTGTATCTCAAGCGCTGCGTGGTGGGCGGAATGGAGCGCGTCTTCGAGATCAATAGGAACTTCCGCAACGAGGGCAGCGACTCCTCGCACTCGCCGGAATTCGCGATGACCGAGTTCTACCAGGCGTATAGCGACTACAACGACATCGCGACCTTGACCAGGGAACTCATCCAGGAGGCGGCCAGAGCCGCCTGTGGTGGTGAGGTCGTCACACTGATCGATGGAACCGAGTACGACCTTTCCGGTGAATGGAAGTGGCTCAGCATGTACGGCTCTCTCGCCGAGAAGGTGGGCGAAGAGGTGACGCCGGACACATCGGTGGAGCGATTGCGGGCCATCGCTGCTGAACAGGGCTTGGAACACGATCCCGCGCTCGGTCACGGCAAGCTGATCGAAGAGCTCTGGGAGCATCTGATCGGCGATCATCTGTACGAGCCGACCTTCGTGAAGGATTTTCCGATCGAGACCTCGCCGTTGACTCGGCAGCACCGCACCGAACCCGGTGTCGCGGAGAAGTGGGACCTCTATATCCGAGGTTTCGAACTGGCCACCGGCTACTCCGAACTCGTCGACCCCGTCGTCGAGCGGGAACGACTGGAAGCGCAGGCCAGGCTGGCAGCGGGCGGCGACGTCGAGGCCATGCGATTGGATGAGGACTTCCTACGGGCTCTGGAGTACGGAATGCCGCCGACTGGAGGCTGCGGAATGGGCGTTGATCGCTTGTTGATGGCCTTGACCGGTGCGGGCATCCGGGAAACGATCCTGTTTCCGCTGGTCCGTCCGGAATGACGCTGCTGCCGATCGGCACCATGCGGTGTCGATCGGCTTCTTCCAAACACGTTGTCTAAGAACTAAGAGCGTTCGGATCCATTTCTGCGGTAATATCGGCTGAAATGAGGCGCGTGGGCAGCCTTGAGCAGATCTTTTCGTGGAAGGACATGGGTCATGGCACAGAAGGTCACAGTCACACTGGTTGATGACTTGGACGGTTCTAAGGCTGACGAGACCGTCGAGTTCACTTTCGATGGAGCCGCTTACCAGATCGACCTTTCCTCGGCCAATGCCGGGGTACTTCGGGATGCGCTGGCCGGTTTCGTCGGGCACGCGCGGCGCTCCGGTGGGCGCAAGCGCAACGTGCGTCCCGGCGGCGACCGGGCCGACGGTGGCAGCACCTCGGCAGGCGATCGGGAGCAGAACCAGGCAATTCGGGAGTGGGCGCGCAAGCGTGGCATGAAGGTCTCCGATCGCGGCCGTATCCCCGCCGATGTCATCGACGCTTACCACGCGGCAAACTGAGCCGTACCGACGAACTCCGACCGTGAAATCGACTGATTGAGTCGATCGCCACACTCGGATTCCTCGGTCGGCAATCCGGCGAAACCGAGTCGGTTCTCGCGGACTGGGAATTGGCCTGGCTCGGCTAGAGCCGGGCCGAGGGGACGCGCGCGTGCTGCGATGTGTGCGGCGCTGAGTCGGGCGAGTGCAAGAACCTTGCCCGCGAAATCACCCTGGAGAAGAAAACGACGCGACCGTTGCCGCTCGGCGACGCGCTTGTGCTCGATTCGGACACGTCTCGATGGCAGCCGGTGGGCGACTGCCATCGAGGGAACGCGTCGCCAGGAGTGTCAGCCGAGCTCGCGCACGCGCGCGTCCCGTTCCGCTGTGCCGACCCGAGGGCACGTCGTGCAGGCCTGGGGCGAACCGGGCAGCGCGTAATGGAAACAGCAGCTTCCTCGACGTCTCGTCCACCGTTCTCCGTCGTCCACCGAGACGCGGTACATCGTCGATACCGAGGTGAACGGGTCCAGCAGTGGGTCGGCGGCGGTGCCGAGCACCAGGGCCGCATCGGCGACCCCGCCGTCCTCGTCGCCGCACATCTGTCCCGCCAGCCACAGCGTGGTGTCCAGCACATCGGTGGCCGCTGCCCAGAGCATTCGGCGGCCCAGGCGGGTGCCGGGGGCGAACGCCGCGACGAAGCGGGCGGCGTGGCCCGCGAACCTCGCCCGGAGCAGATCGGCCAACGCGTGTTCGTCGGCCACCACGGTGGCCGCGCTGGTGTGTGCGGCCGGATCGTCGGGCAGGCAGGCGAACGCCTCGCCGGTCAGGGCGATGCCGTCCAGGTGCGGTCGTCCCTCGGCCAGTCGGAACGCGGTGTGCTCGGGCGCCAGTGACGGCACCCGGCGTGCCGTGTGGAACAGCAGCGCACCCAGGTAGCCCGGCACGCTGAGGTACCAGGACATCACGTAGCCGGCGGTGGTTCGTTCCGGGGCGGCCCCGTAGTTCTCGATCAGCCAGCCGCTCAGCAGTTCACGCCATCGAGTGAACGATGCCGGGTCGTCGAGCAGCGACGAGCAGCGTGACCAACCGGCGTCGAGCGCGGCGTCACCGTGTCGGGCCTCCAGCCACGGCGGAAGGTCCAGTCGGGCGATCGACTCCGCGATGTTCGCGGCCGTCCCCGATCCATAGGCGCCTGACCTGCGAAAAGCCGTGGTCATCGACCGGCTCTCCGTTCCTGGGTGCAGCTGCGGATCGGCACGATGTCCCACCTTCGTCGGGTAACGCCTACTGGTCGACCGTCTGGTTCGGCGATGACAGCCGCGACCAAATCAGGGTTGCCTAAGCTTATCTGGTCGCCGCGCGGGGGAGCCGGGATGGGGCGAGGCTCGCGGGGTGGTTGTGGTCCGACACGGTGCGTGTTCGCTCTCAGCGGACATCGAACGCGCGAGGGCCTGACCTGGAATGAGGCCGCGTCACGCAGCGTTGTGCAGGTTGCGAGTGCTACGGAACGGCCTAAGAGAAGCCGACACCAACTCGATGTCACGGTAATGCCGACTACAGTGGTTGTTAGGGTGCCGACCCCGTCACTACAGCGCCAGAGACCGAAGTCCCTGGTGTGTGGCCGGGCGAGAGCCGCTGCCGCCGCTGTCGAGGAGTGCGAATGTTCGAGAGGTTCACCGACCGCGCGAGGCGGGTGGTCGTCCTGGCCCAAGAAGAGGCCAGGATGCTCAACCACAACTACATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCCAAGGCGCTGGAGTCGCTGGGGATCGCCCTGGAGGGCGTCCGCCAGCAGGTTGAGGAGATCATCGGTCAGGGGCAGCAGGCCCCGAGCGGCCACATCCCCTTCACGCCTCGGGCGAAGAAGGTGCTGGAGCTGTCGCTTCGGGAGGCTCTGCAACTCGGCCACAACTACATCGGCACCGAACACATCCTGTTGGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCGCAGGTGTTGGTCAAGCTGGGTGCCGATCTGAACCGAGTGCGTCAGCAGGTTCTGCAGCTGCTGTCGGGCTACCAGGGCAAGGAACCCGCCGAGACCGGCGGCCGCGGCGAGGGCACGCCGTCTTCCTCGCTGGTGCTCGACCAGTTCGGTCGCAACCTGACGTCGAGCGCTCGGGAGGGCAAGCTCGACCCGGTCATCGGCCGGGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAACCCCGTCCTCATCGGTGAGCCCGGTGTGGGTAAGACGGCCGTCGTCGAGGGCTTGGCGCAGAACATCGTCAAGGGCGAGGTTCCCGAGACCCTCAAGGACAAGCAGCTCTACACGCTGGACCTCGGTTCGCTGGTGGCGGGCTCCCGCTACCGGGGTGATTTCGAGGAGCGCCTGAAGAAGGTGCTCAAGGAGATCCGCACCCGGGGCGACATCATCCTGTTCATCGACGAGATCCACACCCTGGTGGGTGCGGGTGCCGCCGAGGGCGCGATCGACGCCGCGAGCATCCTGAAGCCGATGCTGGCCAGAGGCGAGCTGCAGACGATCGGTGCCACCACGCTCGACGAGTACCGCAAGCACGTCGAGAAGGACCCGGCTCTGGAGCGCAGGTTCCAGCCGATCCAGGTCGGCGAGCCCACGATGGAGCAGACCATCGAGATCCTCAAGGGTCTGCGGGACCGCTACGAGGCGCACCACCGCGTCTCGATCACGGACTCGGCGCTGGTTGCCGCCGCCACGCTGGCGGATCGGTACATCAACGACCGCTTCCTGCCGGACAAGGCGATCGACCTCATCGACGAGGCGGGCGCGCGGATGCGCATCCGTCGGATGACGGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCCGACGTGCGTCGGGACAAGGAATCCGCGATCGACGCGCAGGACTTCGAGCGCGCCGCCCGCCTGCGTGACGAGGAGAAGCAGCTCCTCGGCCAGAAGGCGGAGCGGGAGAAGCAGTGGAAGTCCGGTGACCTCGACGTGGTCGCCGAGGTGGACGACGAGCAGATCGCCGAGGTTCTGGCGAACTGGACCGGCATCCCCGTCTTCAAGCTGACCGAGGAGGAGACGACTCGGCTGCTGCGGATGGAGGAGGAGCTCCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCCGTCTCCCAGGCGATCCGTCGTACCCGCGCCGGTCTGAAGGACCCGAAGCGTCCCTCCGGATCGTTCATCTTCGCCGGCCCCTCGGGTGTCGGTAAGACCGAGCTGTCCAAGGCGCTGGCGAACTTCCTCTTCGGCGAGGACGACGCGCTCATCCAGATCGACATGGGTGAGTTCCACGACCGCTACACCGCTTCTCGGCTGTTCGGCGCGCCCCCCGGGTACGTCGGCTACGAGGAGGGTGGCCAGCTGACCGAGAAGGTGCGGCGTAAGCCGTTCTCGGTGGTGCTCTTCGACGAGATCGAGAAGGCGCACCAGGAGGTCTACAACACGCTGCTCCAGGTTCTCGAGGACGGCAGGCTCACCGACGGTCAGGGCCGCACGGTCGACTTCAAGAACACGGTGATCATCTTCACCTCCAACCTGGGCACGCAGGACATCTCCAAGGCGGTCGGCCTGGGCTTCGCCGGTGGCGGCACCGAGGGCTCGAACTACGACCGGATGAAGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGTCCGGAGTTCCTCAACCGGATCGACGACATCATCGTCTTCCACCAGCTCACCGAGGACGAGATCATCCGGATGGTCGACCTGATGATCGCCAGGGTCGAGACGCAGCTCAAGAACAAGGACATGAGCCTTGAGCTGACCGCCAACGCGAAGAAGCTGCTCGCCAAGCGCGGCTTCGACCCGGTGCTCGGTGCTCGGCCGCTGCGTCGGACGATCCAGCGCGAGATCGAGGACCAGCTGTCCGAGAAGATCCTGTTCGGCGAGCTGGAGGCCGGGCACATCATCATCGGCGACGTCGAGGGCTTCGAGGAGGGCAAGAGCGACGACAAGGCGCGCTTCGTCTTCCGAGGCGAGCCGAAGCCCTCGCAGGTTCCGGATGTCCCGCCGGTGGAGCTGTCCAGCTCGACCGGGGGCAACCAGGAGCTTCCCCCCGCGGAGGGCGAGTCCGAGTGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP014859|316376:363497|324690_325527_+|WP_157420889.1|DBSCAN-SWA
MSENQRRTQKRSIPDRNIVDSSKVNRRIDARNSIDAENVSNVVQANQINGDIVIYEAGPRGTEKNESSYRRARRIGEAGGGSAPPVKRGRIGRYIDQSIDSRSPILIWGILCITANFSLVYFVEYAFGGQQPGEDAAADGESAVVAAAVCVAVVLVALWRNYARRRGSGKWKSLREVHPRIVNVLEQIIFVGPVIALLLALALFAVSGTWQPGALLMSDSVPSESMPSTLSHFGLSLLVTLVLLEIAAFCFYVYWRSLCATVDPIPNEVPRRATKSRE
>NZ_CP014859|316376:363497|342379_343396_+|WP_084642412.1|tRNA|DBSCAN-SWA
MTALPPAEPAIEPGVALDEVRAAVRRLLTGPAAETLDRVGSIAVACSGGADSLALAGGLVQAARRPGLAVHGLVVDHGLQPDSAAVAATAADQLDALGCARVRVLGVTVAGDGGLEAAARRARYDALSTAREHPEQLVLLGHTRDDQAETVLLGLGRGSGPRSIAGMRPLDPPWARPLLECTRATTEAACVALGVTPWRDPHNSARRFTRARLRHEVLPLLEDVLQGGVASALARTAEQLRADLSALDEWSDRALAAARDESHPDELRAGYLADLPAAIRSRVLRSWLRAMGVRDLSSRHLQAVDELASRWRGQGGVWLPGGLVAARAHGRLALQAPD
>NZ_CP014859|316376:363497|339049_340651_+|WP_172803716.1|DBSCAN-SWA
MTQNEPAATTGDQETVALTRPPTALSGDLSPRSSGTVFESAEPPAAASGGEPPEDPPSAPKAAKPPRKRRGLLIGALAVVVVVALGATAVFTIEPVGRVFGIGPSAVPTEPAPDPIDPDFALIPVDHVSAGPTEAGLASALQPSVTAAEVGTLHAVIVDPGTGQSLWGNEADVPATPASTTKILTSAAALLTFPADHTFTTTVVAGPTPGSVILVGGGDPSLTAVPEGTDTLYASNPARISDLAAQVRENAGDIAITEVLVDASRYTGQAIADGWDASDAPSSYGGFIEPLMLDGGRSDPLNDLSQRVGDPALEAGNALAAELGATSVSAVDEAGSPADGEVLGEISSLPLVDLIEAMMLLSDNVAAEMLAREVAIERGAEPSFAGGAASIIEVLGENGFDISQLELSDASGLSNQNLITPNLLGDVLSLAAHPADESDTAVSQQLRPMLTGLAVAGASGKLTDRYPAGASAGRGWVRAKTGSLTAVNGLAGVVTDRDGKLMAFALLSSGTNATVARPALDEVTSALRECGCR
>NZ_CP014859|316376:363497|340705_341755_+|WP_069853172.1|protease|DBSCAN-SWA
MEATADRVPIAWSVAASTAQRLMRPGPVLPLAEAEATVARLRDFSVSAEAHVREVTGLGAGLPLYSGEVVDRPGWAQAAVVGLAALMDDALAGDDPSTLLGGVAAGSAGVQTGVVLAYLGSRVLGQYDPFGGEDGSGHLLLVAPNVVAARQALDVPAEDFEMWVCLHEATHRLQFNAVPWLRDHFASEVGSLLSSMDDTLAQVVVRLPELVRSARRRGAEGEPVGLMELLQSPEQRVRLDRLIALSTLLEGHADHVMDAAGPSVVPSVRRIRARFTARRRGGGVLDRVLRSVLGVEAKVRQYADGAQFTEQVVDAVGMAGFNEVWRSPETLPSRAEISRPSDWLDRVHG
>NZ_CP014859|316376:363497|343467_344016_+|WP_069846038.1|DBSCAN-SWA
MYDGDIASVLISEQQIRDKVTELAAEVAAAYQEAESDLLLVGVLKGAVMFMTDLARELPIPTQLEFMAVSSYGSGTSSSGVVRILKDLDRDIAGRDVLIVEDVIDSGLTLSWLLKNLASRNPKSLEVCTLLRKPDAVQVDVPVRFVGYDIPNEFVVGYGLDYAERYRDLPYVGTLEPRVYSS
>NZ_CP014859|316376:363497|323443_323914_+|WP_069846017.1|DBSCAN-SWA
MTRTDHFHDPDAPQPNSIAIAVSAFVLNEAGDLLMIRRSDNDRYAIPGGQHELGETLSQTVVREVDEETGIAVEPTGVIGLYSNPAHVIAYDDGEVRQEFSICFRARPTGGRLRTSSESKEALWVPRSDVDNLNIHPSIQLRIRHGFEGRTEPFYT
>NZ_CP014859|316376:363497|316376_317675_-|WP_084642400.1|integrase|DBSCAN-SWA
MEEQRTRKPNGRSSIYLGADKLWHGWVTVGVKQDGSLDRRHVKRKTEKSATQAVQALEKQRDAGKSRKAGRSPTVQDWMTVYLDTIAVQKVAPRTYDDYWSKTRNWIIPLLGQHRLDRLEAEHLDAMYGSMFRAKLAPSHVLKVHRILSRALKIAVRRGKVARNVAELIDPPTAERVEQQHLSRGESRNVLAACAGRRNGARWSVGLACGLRQGEVLGLRWQYVDLETGDVRIWWQAQRNTWRHGCTDAHACGSAFHKKSCKRKCATHKGKCPRPCPPGCVSHARHCPDRHGGGVVFRKPKGTGRRTITLPGPLVALLRRQRTRQQTERQTAGSTWEDWDLVFCQPNGRPIDHRKDWEEWGELLRAAGVRYVRPHDARHTAGTLLAEQGVHVRTIQAILGHSDVRTTEGYTHVSSQMTRDAAELMGSALWAE
>NZ_CP014859|316376:363497|317879_319529_-|WP_069846009.1|DBSCAN-SWA
MSTELTTTPTDVQGHTRAERMRQPLAGKVLEATADHHGVCIRPFMMETVDYDTGDMRYVGVPCGSTVESICGPCARKARALRRTQCREGWHLDEEPDFTPEPPTEQQRLLTTYRADLVTDYRKALAEGAETDAEELREAIRDADTDLRDLGVRGKLPNPDVPAKAARKRSTRRRQDAPNLPRRRVEKRTVGREYAGKFRPSMFITLTLDTYGKVRRDGTPVNFATYDYRRAARDIVHFAALVDRWWQNLRRCLGWDVQYFATVEPQKRGAPHLHAAIRGSIPHDVVKQVTAATYHQVWWPHHNQPVYDGTHLPVWDHDRRSFVDPDTRQALPTWDEAVADLEVPVHVSTFGEQVHSKGILGGTPEAGRHIGYLTKYLTKSVSEVVEQDTTRQREHADRLHAELSITPCSPRCPIWLRYGVQPQGARSQMASAHCKGKAHRRATLGLPGRRVLVSRKWSGKSLADHRADRKRFVVETLAAAGIEKPPRDSPRLGWQKVRPGDPGVPPRAHVLMHAISERLTWKTEYDRALQAAQPPPGGEPHLSATPIAA
>NZ_CP014859|316376:363497|346755_347385_+|WP_069846041.1|DBSCAN-SWA
MTDLINENGQAEAGARPSSRPAFDQPRAEAAVRELLLACGEDPDREGLRDTPARVGRAYQEMFAGLFTDPDEVLDKTFDEGHDEMVLVTDIPIYSYCEHHLLPFHGSAHVGYIPNQQGRVTGLSKLARVVDLYARRPQVQERLTSQVADALVRKLDPRGVIVVIEAEHLCMSMRGVRKPGARTTTSAVRGLFRSSPSSRAEALDLIRGH
>NZ_CP014859|316376:363497|328900_329383_+|WP_069846021.1|DBSCAN-SWA
MTDTPNTAKKKKRWPWIVGGIVAVIAVAAVTTGGEDTTTPDTATGDTTEGETAPAEDDAAASNIATVVYEVTGTGTSSMITYTTDGQTDMEQVGDVELPWEHTIELPADDPLLVVQVSGQQAGTGEISCRITVDGEEVAQATSDGDYVMASCSESIGAFS
>NZ_CP014859|316376:363497|329466_330078_-|WP_084642405.1|DBSCAN-SWA
MGNERHPGTVRAASRRAIPPGRAADLRDLPIRSDGRVLLRAWQIDDLPAIIEAADDPYIPLITTIPAGCSMVQASAWLRRQWTQAAEGFGIPLAIIDESTGESAGMVTINGIDWTHRRGAMGYWLLPRHRGKGLARAAVELTVGLARDLDLLRVEALVEVDNGPSQAVCRANGFAEEGTLRSYLRIGERHRDMIMFSRLLSGS
>NZ_CP014859|316376:363497|338728_338893_-|WP_172803715.1|DBSCAN-SWA
MRPLLLWWLMLLPLLRRRLLKVLLRVPLLALLSRTRSLCRRRRGAHRIRRPAAF
>NZ_CP014859|316376:363497|334363_335143_+|WP_069846028.1|protease|DBSCAN-SWA
MRMPRTLGAVLAAVVMFTAALAGAGSAVAGPQSAPRIVGGTQSVEKYSFMASIQRKSEGRDHWCGGALVDPIWVVTTAHCLQGDLDAYTVRVGSNDRTAGGEYRRVVEMIAHPNWDGLHGDIAMLRLERAVTAAPVAIAKSSPIYGDPIRLLGWGKTCNTYECSWEYPKLLREIDRDVAFDNECSRATIDGRTELCVDVTSKATSCYGDSGGPAVERMLAGGWGLVGLDGRGGDSVCGERGLIYTDVTAYQDWIRSTVA
>NZ_CP014859|316376:363497|322112_322532_-|WP_069846015.1|DBSCAN-SWA
MPVPNGYRFSVPFDDVFPDGAFVLGVEQGMDFDNGQRRPAKDKVTGRLVWNVQVTDPAANGRNTGVVVKIAADVQPIPPDALPGTPFRPVFFEGLTATAYEQNGRVAFSLRAASMRAPGAGAGRSSAGKTSQPTAQAAA
>NZ_CP014859|316376:363497|328190_328436_-|WP_084642404.1|DBSCAN-SWA
MRRNEKDRHVVPNSNGGWNVEKPHASRASSHHQTQNQAIGQARQTTARTGGETVIHGADGRIRGKDTSRRGNDPNPPRDRR
>NZ_CP014859|316376:363497|348226_348610_+|WP_069846045.1|DBSCAN-SWA
MTDRIVLTGLKVRGRHGVFEHERRDGQDFIVDVTVWIDTDRAARSDDVQDTLDYGVLATRMAEIVGGEPRNLIETVAAEAADSVLSDPRVHAVEVTVHKPQAPIPLEFADVAVTVRRSRRAGRGRAD
>NZ_CP014859|316376:363497|337724_338243_-|WP_069846034.1|DBSCAN-SWA
MEFDVTIEIPKGERNKYEMDHETGRIRLDRTLFTATQYPADYGFIEHTLGEDGDPLDAMVIVQEPTFPGCLIRARAIGMFRMRDEKGGDDKVLCVPAEDPRSEHLRDIHHLAEFYRMEIQHFFSVYKELEPGKSVEGATWVGRTDAQIEIERSYQRAIDTGYYEGKHESPKV
>NZ_CP014859|316376:363497|357334_358789_+|WP_069853174.1|tRNA|DBSCAN-SWA
MKVRREKRSRLLESGIEPYPVVLPITHTVAAIRAKHTDLEPDTATGEIVGISGRVMFLRNTGKLCFATLRSGDGSELQAMLSLAQIGAESLASWKADVDLGDHVFVHGEVITSRRGELSVMADEWRIAAKALRPLPVTHKELSEETRVRQRYVDLIVRPQARRIVETRAAVVRSLRESFHRHGFTEVETPMLQTLYGGAAARPFHTHSNAFDIDLYLRIAPELYLKRCVVGGMERVFEINRNFRNEGSDSSHSPEFAMTEFYQAYSDYNDIATLTRELIQEAARAACGGEVVTLIDGTEYDLSGEWKWLSMYGSLAEKVGEEVTPDTSVERLRAIAAEQGLEHDPALGHGKLIEELWEHLIGDHLYEPTFVKDFPIETSPLTRQHRTEPGVAEKWDLYIRGFELATGYSELVDPVVERERLEAQARLAAGGDVEAMRLDEDFLRALEYGMPPTGGCGMGVDRLLMALTGAGIRETILFPLVRPE
>NZ_CP014859|316376:363497|317674_317863_-|WP_069846007.1|DBSCAN-SWA
MDKLLYRVEEAAAILSIGRTRTFGLINSGELRSVRIGGSRRVPRAALAEFLHSLESEQAEAA
>NZ_CP014859|316376:363497|352242_353757_+|WP_084643523.1|protease|DBSCAN-SWA
MTSSQASRWQRFLLPVLGVVILGLCGLTLLGLTHARVGAVALVVGAAAALLPLGPVIATFLWVDRWEPEPPRLLFAAFLWGACGATIAALLINDTAQVVGEVLLGTGGGDLVAALISAPLFEEAAKGLFVLAVLLRRRQEFNGIVDGIVYAGITGVGFAFTENITYFGLAFVQGGFGDMSGGVVAVFVLRGVLSPFTHSLFGAMLGIGLGIAACTSRPRMRIAAPLIGYLMAVLLHALWNGAATLGGGRIFINVYFLVMVPIFLSTALLVCWQRRREQHVVVTQLPGFAAEGWIAASEIGLLASLTSRKEWRVAVRKRSGASAGKAVAAYQLAVTELAFVRNQLAGGRTFPETAERLDQAVARLIRSRAAVLRSPGALADAARSTAGIRRRNRPSRGSGWLFDRQPVLLRALGPPRRPVSTEVTLPGIVVGSNRSADETLPIPKMVLEPLSSGAPTVRHDGVVAPVEPALTSAREPVIPAQSSESTDVTVVIDPVPPTSGEPKA
>NZ_CP014859|316376:363497|359625_360495_-|WP_084643524.1|DBSCAN-SWA
MTTAFRRSGAYGSGTAANIAESIARLDLPPWLEARHGDAALDAGWSRCSSLLDDPASFTRWRELLSGWLIENYGAAPERTTAGYVMSWYLSVPGYLGALLFHTARRVPSLAPEHTAFRLAEGRPHLDGIALTGEAFACLPDDPAAHTSAATVVADEHALADLLRARFAGHAARFVAAFAPGTRLGRRMLWAAATDVLDTTLWLAGQMCGDEDGGVADAALVLGTAADPLLDPFTSVSTMYRVSVDDGERWTRRRGSCCFHYALPGSPQACTTCPRVGTAERDARVRELG
>NZ_CP014859|316376:363497|335268_335820_+|WP_084642409.1|DBSCAN-SWA
MTQATGESMDAAAASRPEALEAKAVEVEAVGQAIARVVRMSNCATAHAGRLGVPSGWEKATYLVLFHLEAGARRSGSVAEALHLDPSTISRQVATLVKSGLVERTIDPEDGRASLLSITEQGRSILAAHRATRRELIDRMITDWPSRDRQDLARLLTRLADALETKLPAYVADVIQARHEGES
>NZ_CP014859|316376:363497|321523_321889_-|WP_157420886.1|DBSCAN-SWA
MTTAPRLVVLPAVGACAVFGANLPGRGPTFLLDLGAVHVEIPIPPDKLSRACMADFLRTLSFAADRASEWLDHAAGPAGGTVITPEPPTGIPQGRGRHCWPEKDQDPPDRGISGSGWWSSS
>NZ_CP014859|316376:363497|356388_357174_+|WP_069846059.1|DBSCAN-SWA
MLLTIDVGNTNIVFGLYVGSGPDARLLRDWRMRTDARMTADELAWTMRGLLGEHADRITGISALSTVPAVARELRVMLARYYAEVPTLIVAPGVRTGVPLLVDNPKEVGGDRVVNTLAAHHLYDTACVVVDFGTSTNIDVISRKGEFLGGVFAPGIEISVDALAARAAQLRKVELLRPRNVIGKNTVECLQSGILFGFAGQVDGLVRRILAELSAGEHGPVTVLATGGLAPLVIGESETITTHVPDLTLIGLRLVYERNMS
>NZ_CP014859|316376:363497|321885_322089_-|WP_157420887.1|DBSCAN-SWA
MVTVHLTADLPVRVRALPFADRVEIRLGKAFPVALVIDRGALTRLSSAVSEGIAALEAADGHREGDR
>NZ_CP014859|316376:363497|349669_351055_+|WP_157420893.1|DBSCAN-SWA
MVGLSDTDGERHRIGRGTILWALGAGLALIATVVLVLGDDARLLRLGLLAALWTALLGAFAAARYRKDANARTGEADRLQQIYELELEREIAARREYELEVEAETRRQVEEEVRDESRRELDALRGELRNLRENLEALLGGDVLVERVALRAESTRLRSLSDQSRVIAAHDDEIRSITSSSSSSVVSAEETQIIDALVEVENAVQEMELRSGDGRGIGSPGRNRPGRGDRPHPVEQWRAGAPRREDSGRTATRRPGQRPPAQVPPQARPAAGHDRQEDQSSRSMRMEVVGEVESPQPMDQRDQPPARPRKPAQAPPPPQKQPPARGPNRPPARRNPPQPPEQPTRQAPPPAPKRPTREEPTRQINRPKRPAPAAPPPAPVPAPVSRATEETAFDGIDGWQPEIEQPVAVEPEPTGRRAARGRRAAPEDGDDAGAHASGRSVSELLAAYSDEQPRRHRRRRD
>NZ_CP014859|316376:363497|322684_323428_+|WP_069853168.1|DBSCAN-SWA
MPNERLREALLKQGLNLDHVARAANVDRKTVERWITKNRLPYPKHRHTIAAMVRESENYLWPDALPAERKAEVGVSEVVKVYPHRNAIPVELWDRLISEATKQVEILVHAGLFLVERPTFVKDLAKKAENGAQIRLLFGDPASREVVRRSEEEQLGKATLGGRIRNALAFYRPLRAVPGVELRFHKTTLYNSVFRFDDEMVINTHVYGFQGAHAPALHLRRLSAGDVFETYSESFETVWAESKPADF
>NZ_CP014859|316376:363497|360938_363497_+|WP_069846062.1|protease|DBSCAN-SWA
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGIALEGVRQQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVLQLLSGYQGKEPAETGGRGEGTPSSSLVLDQFGRNLTSSAREGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQNIVKGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDEIHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKHVEKDPALERRFQPIQVGEPTMEQTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIADVRRDKESAIDAQDFERAARLRDEEKQLLGQKAEREKQWKSGDLDVVAEVDDEQIAEVLANWTGIPVFKLTEEETTRLLRMEEELHKRIIGQEDAVKAVSQAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGEDDALIQIDMGEFHDRYTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEVYNTLLQVLEDGRLTDGQGRTVDFKNTVIIFTSNLGTQDISKAVGLGFAGGGTEGSNYDRMKQKVNDELKKHFRPEFLNRIDDIIVFHQLTEDEIIRMVDLMIARVETQLKNKDMSLELTANAKKLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFGELEAGHIIIGDVEGFEEGKSDDKARFVFRGEPKPSQVPDVPPVELSSSTGGNQELPPAEGESE
>NZ_CP014859|316376:363497|335819_337640_+|WP_069846032.1|DBSCAN-SWA
MSEALAPPGQVAKSGDGGLSHRQILTVLSGLMMGMFLAALDQTIVASAMRVIADELHGQTAQAWATTAYLITATITTPLYGKLSDIYGRKPLYLTAIGLFLVGSVLCGIAGSIYELAAYRAIQGLGAGGLMSLAMTIIADMVAPRQRARYQGYILAVFGVSSVLGPVVGGFFAGQESLLGVAGWRWVFLVNVPVALIALVVVAKVLNLPHNRVNHRVDYWGAAALVLALVPLLIVAEQGREWGWGAGISMLMYAIGAVGVVLFVLVERRMGDEALLPPRLFRSGTFRLGNLMSFIIGLGMFGGMVSLPLYLQIVKSQSPTQAGLLMLPLTFGIMTTTFVVGKLIAKTGRIKVFPVLGAGVMAAALFLFSTIDADTPMVLLGALMVLFGSGLGLSMQTVTLLVQNDAPPADNGSATAAVTFFRQTGGTAGTAVFLSILFSVLAGRIADAFTSAADDPAFNAALQDPAVLADPANQGFLENLQGSGSELDLNDTSFLTTIDPRLAAPVLDGFASAMSTVFLVGGLVMLVAFLLSWFVPDVELGNQSGIQRMQAERAAADRAADSESSATRHADSVHAEDAGDPEGAVERPRASTIGASGSGDRSPDDA
>NZ_CP014859|316376:363497|349115_349583_+|WP_069846048.1|DBSCAN-SWA
MKFTRARDLGTAVIIAGLLFNLVVQAGYGTWPPLPLLAGSPLFVLAVVEVVLAFSLRSRIGRRPGAPPVEPLVAARAVALAKATSLTSAIVLGAWLGVVGYLIPLIGDISAAGADMAAAVVGAVSAAAAIAAGLWLEHCCRTPEDDDEKHPDRHA
>NZ_CP014859|316376:363497|319525_321049_-|WP_069846010.1|DBSCAN-SWA
MPERSRWIDPAPLEVARPRLPWWTHSPRWALVLVAPLIAVGLAVWLTVVVARKAARYPLAFAVVLVLVVAWHGWGWPVALILGAILALVLVGWWWRFRPSFVRLVLVEIRSEWRRLIVYTPVWLRTMRFCHLERTVNGKVHVPTFIRVRADGWRDRVTVKLLHGQTPGEFETRAEALAHSFDARTCRVRVVGPRRIVLDLIHGDPLTQPVPPPSLPDGTDDTTPTKDLERVPVGTTETGRPWLLRLFGSHLLAVGATGAGKASVVWSLLWSLAPMLRSGLIRVYGIDPKGGMELGKAPELFHRLVFDNGLAAVKLLEELATEVKQRAASFRGSKRRWSVDCGVPFLLLVVDELADVVAYQTDRKLKERANSALQTITSQGRAPGVCVIGEIQDPRKEILSFRHLFPTRIALRLDEPGQVDMVLGDGVRERGAVAHEISETTPGVAWVKYTDRREPVRARAFHITDGDLDRLVDYVTADATDSATVHELPARTVDADPDADDVVGEAA
>NZ_CP014859|316376:363497|330469_332263_+|WP_069846025.1|DBSCAN-SWA
MRKSRWAAAGLAVLLTGAAFGTSVASEEPFVDPAGLDLESKGTFDVMSDIQGALEAFNDVRLAAHDLAPDSKALMINGDIVDRGYDFEYDEVSEIIASTPGPGADTTLSSIGNHEAYSPAWCSPTELCQPSWPNGFTEEELYQSFFDFAGRDRVYDEIVVDGIPLITLGTERLMWWEDPNLDDHIYLSDEQLSWLRARLDHHTRNGEPVFIATHYPLENTVSASDGTSGQFHLQDRELRQILGDYPQAVLFSSHTHSNLREDDWATRVKVPGGHPDGFTAVNTGAVLNRQVIQVTAGSDGARIRARDVAAGEWIQDLVVPTVDPAEPASGLLVEPSQDNIAPGGSVEIDAEFVNLGSKRLIHAGLEPVVPQGWQAELVEQSGPKHLDRGATTSATWRMTPPEGVEAGDVEFAVDAVHGRGSKATRVTEQTEVQIVSAPAGDVFVSDLPFLTAENGVGPVERDQSNGAIGRNDGHPLTVDGVTYEKGLGTMAPSETTLYLGGECARFAASVGIDDRAPQSSQNRPDDGRGDGGDVVFQVWADDEKVWDSGLVSSGEGARDMDVHLNDAETLRLVVTDGGDENWWDYADWGQARLTCAG
>NZ_CP014859|316376:363497|347387_348230_+|WP_069846043.1|DBSCAN-SWA
MHRLLPDPGRCAVLGVLNVTPDSFSDGGRYLDRDEAVAHGVRMSRQGADLIDVGGESTRPGSDRVPAEVELDRVVPVIRELVAEGVPVSIDTTRSVVAEAAVAAGATVINDVSGGLADDRMAKVVADADVPWVLMHWRGHSREMNSLAEYSDVVTDVRTELAARVDAALAAGVAASALVLDPGLGFAKTAEHNWQLLGRLDELSSLGLPILIGASRKRFLGAVLADDDGKPRPAAGREVAGAVISALSAQAGAWGVRVHDVVNSLDAVRVAAAWKGGNDR
>NZ_CP014859|316376:363497|327569_327845_-|WP_084642402.1|DBSCAN-SWA
MAYSTRMAAAHHKVSHVGELKWSGKKDLALLPDATKRGYAVFLTKDARQLEDPLETDAIKKSGMHHVFNPGSKQRFERVDPAKAPPRYWPR
>NZ_CP014859|316376:363497|323904_324462_-|WP_157420888.1|DBSCAN-SWA
MRSESWAYELACERLSVSLPQRWAHVEAVARRAGTASVVVGDGAGVLWTAAVLHDVGYAPELAATGLHSLDGARFLRGLGVDERVVGLVAFHSAARWDAELAGLASSLGEFVDEGPTVVRDALWWADMTVGPDGAVVGFEERMAEVRRRYGPDHAVSRAVNASLSERAEAVNRTESRLRAAGVQV
>NZ_CP014859|316376:363497|348609_349119_+|WP_069846046.1|DBSCAN-SWA
MSRAVLSLGSNLGDRLAMLRLAVTGLGEAVRAVSPVYETAPWGVLDQPDFLNAVVIVEDDIGAWDWLRRSQALETQAQRVREIRWGPRTLDVDVVTVDEVRSDDPELLLPHPGAGDRASVLVPWHDIDPDAVLPGRGPIRDLLAGLDSTDLRRLDTGLLDEHPTTRGSR
>NZ_CP014859|316376:363497|358945_359296_+|WP_069846060.1|DBSCAN-SWA
MAQKVTVTLVDDLDGSKADETVEFTFDGAAYQIDLSSANAGVLRDALAGFVGHARRSGGRKRNVRPGGDRADGGSTSAGDREQNQAIREWARKRGMKVSDRGRIPADVIDAYHAAN
>NZ_CP014859|316376:363497|351432_352038_+|WP_069846051.1|DBSCAN-SWA
MKYEELAGPDVVVDPADRRSSARRIPVQARRSAAAGNALPFGSPPRSLRAAAVLLAVLAAAMLLATFVVAFWLWQGELVATPPAVVFFCLFALLPVSIVSLLWAAARAVWHGRSWGLSLAAGICVLSVIGAGFLVVDFGYRSVVGLTIDAASWWLLLVVAAVMLLGSIAAVLLRRLRYNPFVLAGGIRGMDDATMSSEAGD
>NZ_CP014859|316376:363497|344310_346731_+|WP_069846039.1|protease|DBSCAN-SWA
MDRKRLLRNPLLWIMAVLLLWLGFSALFDDTRGYEQVPTSTALEQITNGNVREAVLEDREQQLRLTLENPVNGNNQLITQFPSQATDEFTQALIDADIPGDWDTTVTQDSLLFQVLIYLIPLGLLLLLLMWMMNNAQGGGNRVMNFGKSKAKQLNKDMPQTSFSDVAGAQEAVDELYEIKDFLQAPGRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFEQAKQNAPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDSRGGIILIAATNRPDILDPALLRPGRFDRQIPVAAPDMSGRKAILQVHAKGKPFAPDVDLVSLAKRTVGMSGADLANVINEAALLTARQNEQLITGASLEESVDRVIGGPARRSRVVSEKEKKLVAYHEGGHALAAWAMPDLEPVYKLTILPRGRTGGHALVVPEDDKELMTRSEMIGRLVFALGGRSAEELVFHEPTTGASSDIDQATKIARAMVTEYGMSARLGAVKYGKDEGDPFLGRSMGSQPNYSLEAAHEIDKEVRALIEAAHTEAWEILRTYRDILDDLVRELLEKETLQRRDLERIFAGVEKRPRITAFNDFGGRTPSDKPPIKSPGELAKERGEPWPPIVESEPTPVGEAHGGGDLPDGPPGSHEPDGLPGTGHGPGEGVPPHDPEPRTYPSTDTDPTVRRPVPQGVGPQGVNHNGVGSGPPNYGAPPGWTPATSPTGPPSSWTPSWERQSGPSWERRDEAGAVSGVNPTHDGTERINRDDLRPDRPVDDEDQSDGGGR
>NZ_CP014859|316376:363497|353905_354823_+|WP_069846054.1|DBSCAN-SWA
MIDNAGVRPARLAVGVISAGRVGAVLGASLARAGHVVVATSAVSDASLRRAEQLLPDVPVLAPDEVATRADLVMLAVPDDVLPGMVAGLVATGALRAGQIVAHTSGAHGVDVLTPAAELGALPLALHPVMTFTGRSEDLERLAACCIGVTASGDPNSPVEPGWNVGEALVVEIGAEPVRIPEAVRPLYHAALAHGANHLITLLTECVGLLSQAGVAHPERLLGPLCGAAMDNALRHGDRALTGPVARGDLSTLRTHLDVLGEVAPEVVPSYRVLAARTADRARAAGLLSDSTAAEVDDLLNEEPR
>NZ_CP014859|316376:363497|354819_355803_+|WP_069846056.1|DBSCAN-SWA
MTETQATPGAPGESPLFAPGDTTVHSDPAQLARVTRALRATGRRIVLVPTMGALHRGHRELIRRAKRVPNTIVVVSIFVNPRQFGAGEDFERYPRDLDTDVAVCRAEQVELVFAPTAAAMYGAGTSITVSAGPLGDELEGASRPGHFAGVLTVVAKLLNIVRPDFAFFGEKDYQQLVLLRRMGRELDFDASIVGIPTIREHDGLALSSRNVYLDAEARNAAVVLSAALTAGVYAARSGGDAARVLATAREVLDGEPALDVDYLELRDVELNAVDEQREARLLVAARVGAVRLIDNVAIAFGTAEEQPGEVADAPAADGAATDSAESR
>NZ_CP014859|316376:363497|355816_356347_+|WP_069846057.1|DBSCAN-SWA
MLRTMLKSKIHRATVTQADLHYVGSVTVDEDLMDAADLLAGEQVAIVDVTNGARLETYVIPGERGTGVLGINGAAAHLVHPGDLVILIAYGLMDAAEIREHRPSVVFVDADNKVISLDADPAVVPDGFGLSSGSIDSRSADSAPTAGGSTTARSESIAAGETDDAVRLDALLQSER
>NZ_CP014859|316376:363497|333136_334033_-|WP_069846026.1|DBSCAN-SWA
MSPLFALVRGALSATSAIAPDLAGRLAFELFRRVPPRGKVRPAELPVHQAAEVDRMTVAGREVRLYRWGTGDRPVLLVHGWQSRASRFAGLIDELQATGRSAIAFDAPGHGDSEGNTTTVVEYHEIIAALHRRYGDFEAVVGHSFGVLCSFYALRAGVRADRIVGISGVGDFDYLVAEFGRMLSLRPEVTARIRTHIEKRLFPELVDVWEKFQVWHRPESVPGELLFLHDDDDQRTPPEHSLRMATTFGDRARLVTSRGLGHSRIVADPTTVRTIMDFLTRAPGGITKPAEEDQVRAR
>NZ_CP014859|316376:363497|332371_333124_+|WP_157420891.1|DBSCAN-SWA
MPRVRFGPGVHIAKGGQLGRQTGQARGQHIPDPVDTNHSSGDGRVERGNRTRRAVLRHAVDIASVDGLDGLSIGRLASELGHSKSGIFALFGSKEELQVATVHEAVRLYESYVVEPARTTEAGLQRVWRLAELWFDYSRSRVFPGGCFFFGVSAEVDARPGPVRDAVGAARSAWVGYLAHQLELGRRAGTLRPEVDIDQTVFEITAFLEASNGASLLHDDDVAYDRAAKAVLRVLREASAHPDRLPLAPR
>NZ_CP014859|316376:363497|325839_327147_-|WP_157420890.1|DBSCAN-SWA
MHESNRFSPTFRGGQLASRVEAQDTVCMILLVEAIGGLIDEIPARQLTEAGLVIFEKLEDIEISWPNGRALISVKDKAVSYSDITNEIEKFSKLYSNTSDNNGMVFRLEAGSLSGSKARTLIDDLRALKSVAQSGVISEWRMAAQDFEAEHQAPSSIAAITTVCIRDMNINLDVGKAIFASRFRTVFPVQQFTDDKIFENYSRMIYEQIAPARRTRATIRIDILKKSLLEPLVPRMLHGINTDVMKTRYGYVVDPTLSEKIDLSLKIIQASKRKALKRWRRHARKHAVASLLYRGHVACPFCNHPLMFSTFGDNSVGCPNCHYIPYLTIFYACDCTEPVALVRQPSVETIETFSEILEEVKINSPTCDKCGQRVDREKLYSRVFSATIPWPPESYNENELITIRTKIGWEGRSYKIPGETPLSLIKKGEWKESAE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
316253:316296	attL	NA	NA	NA	NA
WP_084642400.1|316376_317675_-|integrase	tyrosine-type recombinase/integrase	A0A286MRB3	Mycobacterium_phage	1.7e-42	31.0
WP_069846007.1|317674_317863_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_069846009.1|317879_319529_-	replication initiator protein	NA	NA	NA	NA
WP_069846010.1|319525_321049_-	cell division protein FtsK	G1D482	Mycobacterium_virus	5.3e-11	26.6
WP_157420886.1|321523_321889_-	hypothetical protein	NA	NA	NA	NA
WP_157420887.1|321885_322089_-	hypothetical protein	NA	NA	NA	NA
WP_069846015.1|322112_322532_-	hypothetical protein	NA	NA	NA	NA
WP_069853168.1|322684_323428_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069846017.1|323443_323914_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_157420888.1|323904_324462_-	HD domain-containing protein	NA	NA	NA	NA
WP_157420889.1|324690_325527_+	hypothetical protein	NA	NA	NA	NA
WP_157420890.1|325839_327147_-	hypothetical protein	NA	NA	NA	NA
WP_084642402.1|327569_327845_-	hypothetical protein	NA	NA	NA	NA
327413:327456	attR	NA	NA	NA	NA
WP_084642404.1|328190_328436_-	DUF2188 domain-containing protein	NA	NA	NA	NA
WP_069846021.1|328900_329383_+	hypothetical protein	NA	NA	NA	NA
WP_084642405.1|329466_330078_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_069846025.1|330469_332263_+	NPCBM/NEW2 domain-containing protein	NA	NA	NA	NA
WP_157420891.1|332371_333124_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_069846026.1|333136_334033_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_069846028.1|334363_335143_+|protease	serine protease	NA	NA	NA	NA
WP_084642409.1|335268_335820_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_069846032.1|335819_337640_+	MFS transporter	NA	NA	NA	NA
WP_069846034.1|337724_338243_-	inorganic diphosphatase	NA	NA	NA	NA
WP_172803715.1|338728_338893_-	hypothetical protein	NA	NA	NA	NA
WP_172803716.1|339049_340651_+	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
WP_069853172.1|340705_341755_+|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
WP_084642412.1|342379_343396_+|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_069846038.1|343467_344016_+	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	2.0e-08	29.0
WP_069846039.1|344310_346731_+|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	1.6e-110	49.2
WP_069846041.1|346755_347385_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	3.6e-46	51.2
WP_069846043.1|347387_348230_+	dihydropteroate synthase	S4VNV0	Pandoravirus	1.0e-19	33.5
WP_069846045.1|348226_348610_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_069846046.1|348609_349119_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_069846048.1|349115_349583_+	DUF3180 domain-containing protein	NA	NA	NA	NA
WP_157420893.1|349669_351055_+	hypothetical protein	NA	NA	NA	NA
WP_069846051.1|351432_352038_+	hypothetical protein	NA	NA	NA	NA
WP_084643523.1|352242_353757_+|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_069846054.1|353905_354823_+	DUF2520 domain-containing protein	NA	NA	NA	NA
WP_069846056.1|354819_355803_+	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_069846057.1|355816_356347_+	aspartate 1-decarboxylase	NA	NA	NA	NA
WP_069846059.1|356388_357174_+	type III pantothenate kinase	NA	NA	NA	NA
WP_069853174.1|357334_358789_+|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	1.7e-75	37.3
WP_069846060.1|358945_359296_+	Lsr2 family protein	A0A160DEV0	Gordonia_phage	3.7e-16	44.2
WP_084643524.1|359625_360495_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_069846062.1|360938_363497_+|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	6.0e-132	40.2