CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017476	Hydrogenophaga crassostreae strain LPB0072 chromosome, complete genome	6 crisprs	DinG,WYL,DEDDh,csa3,RT,cas3	2	2	1	0

1. NZ_CP017476

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017476_1

• CRISPR_ID: NZ_CP017476_1
• CRISPR_location: 1424545-1424761
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP017476_1

Consensus_repeat	Method
TCAGCGCAGGGCCGCCCCAGGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCG	CRISPRCasFinder

spacers of NZ_CP017476_1

>1.1|1424598|111|NZ_CP017476|CRISPRCasFinder
AGCAGCGGCGCAGCGTGGGGGCCATCGATTCAGCGCAGGGCCGCCCCAAGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCGCGCAGCGGCGCAGCGTGGGGGCCATCGAT

CRISPR arrays and Neighbor proteins around NZ_CP017476_1

CRISPR arrays

The CRISPR arrays of NZ_CP017476_1

>merge|NZ_CP017476|1|1424545-1424761|CRISPRCasFinder
TCAGCGCAGGGCCGCCCCAGGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCGAGCAGCGGCGCAGCGTGGGGGCCATCGATTCAGCGCAGGGCCGCCCCAAGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCGCGCAGCGGCGCAGCGTGGGGGCCATCGATTCAGCGCAGGGCCGCCCCAAGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCG

>NZ_CP017476|1|1|1424545-1424761|CRISPRCasFinder
TCAGCGCAGGGCCGCCCCAGGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCG	AGCAGCGGCGCAGCGTGGGGGCCATCGATTCAGCGCAGGGCCGCCCCAAGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCGCGCAGCGGCGCAGCGTGGGGGCCATCGAT
TCAGCGCAGGGCCGCCCCAAGCGGAATCAGCCCCCTCGGGGGGCAGCGACCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017476.1|WP_066093020.1|1424874_1425816_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|380381
NZ_CP017476.1|WP_066093029.1|1429212_1430043_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP017476.1|WP_066093626.1|1432601_1433459_+|shikimate-dehydrogenase	unknown	unknown	gnl|CDD|223247
NZ_CP017476.1|WP_066093616.1|1412698_1413205_-|TRAP-transporter-small-permease	unknown	unknown	gnl|CDD|377284
NZ_CP017476.1|WP_066093011.1|1419464_1420415_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176161
NZ_CP017476.1|WP_066093619.1|1420526_1421303_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187620
NZ_CP017476.1|WP_066093026.1|1428025_1429072_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226359
NZ_CP017476.1|WP_066093032.1|1430052_1430913_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP017476.1|WP_066093034.1|1431045_1432356_-|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270303
NZ_CP017476.1|WP_066093008.1|1418474_1419458_+|nitronate-monooxygenase	unknown	unknown	gnl|CDD|224981
NZ_CP017476.1|WP_066093002.1|1415550_1416483_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl|CDD|224936
NZ_CP017476.1|WP_066093017.1|1423790_1424468_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187619
NZ_CP017476.1|WP_066093040.1|1434932_1436462_+|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP017476.1|WP_066092999.1|1414680_1415430_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl|CDD|224997
NZ_CP017476.1|WP_066093023.1|1427271_1428000_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|226674
NZ_CP017476.1|WP_082877035.1|1421391_1423716_-|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|227342
NZ_CP017476.1|WP_082877036.1|1433772_1434831_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176126
NZ_CP017476.1|WP_066092996.1|1413279_1414296_-|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270383
NZ_CP017476.1|WP_066093622.1|1425842_1427252_-|mannitol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223324
NZ_CP017476.1|WP_066093005.1|1416558_1418349_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173842

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017476.1|WP_066093020.1|1424874_1425816_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|380381	cd06976, cupin_MtlR-like_N, AraC/XylS family transcriptional regulators similar to MtlR, N-terminal cupin domain. MtlR is a Pseudomonas fluorescens protein that acts as a transcriptional regulator of the mannitol utilization genes. It has an N-terminal cupin domain (represented by this alignment) and a C-terminal AraC/XylS family helix-turn-helix (HTH) DNA-binding domain. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	7.16441e-33
NZ_CP017476.1|WP_066093029.1|1429212_1430043_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.77592e-65
NZ_CP017476.1|WP_066093626.1|1432601_1433459_+|shikimate-dehydrogenase	gnl|CDD|223247	COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and metabolism].	7.23462e-95
NZ_CP017476.1|WP_066093616.1|1412698_1413205_-|TRAP-transporter-small-permease	gnl|CDD|377284	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component. The function of the members of this family is unknown, but DctQ homologs are invariably found in the tripartite ATP-independent periplasmic transporters.	1.67616e-11
NZ_CP017476.1|WP_066093011.1|1419464_1420415_-|LysR-family-transcriptional-regulator	gnl|CDD|176161	cd08472, PBP2_CrgA_like_3, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 3. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.28229e-98
NZ_CP017476.1|WP_066093619.1|1420526_1421303_+|SDR-family-oxidoreductase	gnl|CDD|187620	cd05362, THN_reductase-like_SDR_c, tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs. 1,3,6,8-tetrahydroxynaphthalene reductase (4HNR) of Magnaporthe grisea and the related 1,3,8-trihydroxynaphthalene reductase (3HNR) are typical members of the SDR family containing the canonical glycine rich NAD(P)-binding site and active site tetrad, and function in fungal melanin biosynthesis. This subgroup also includes an SDR from Norway spruce that may function to protect against both biotic and abitoic stress. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.23625e-75
NZ_CP017476.1|WP_066093026.1|1428025_1429072_-|ABC-transporter-ATP-binding-protein	gnl|CDD|226359	COG3839, MalK, ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism].	4.86464e-173
NZ_CP017476.1|WP_066093032.1|1430052_1430913_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.96838e-63
NZ_CP017476.1|WP_066093034.1|1431045_1432356_-|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.79847e-69
NZ_CP017476.1|WP_066093008.1|1418474_1419458_+|nitronate-monooxygenase	gnl|CDD|224981	COG2070, COG2070, Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only].	1.48409e-83
NZ_CP017476.1|WP_066093002.1|1415550_1416483_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl|CDD|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	1.33572e-118
NZ_CP017476.1|WP_066093017.1|1423790_1424468_-|SDR-family-oxidoreductase	gnl|CDD|187619	cd05361, haloalcohol_DH_SDR_c-like, haloalcohol dehalogenase, classical (c) SDRs. Dehalogenases cleave carbon-halogen bonds. Haloalcohol dehalogenase show low sequence similarity to short-chain dehydrogenases/reductases (SDRs). Like the SDRs, haloalcohol dehalogenases have a conserved catalytic triad (Ser-Tyr-Lys/Arg), and form a Rossmann fold. However, the normal classical SDR NAD(P)-binding motif (TGXXGXG) and NAD-binding function is replaced with a halide binding site, allowing the enzyme to catalyze a dehalogenation reaction. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.51549e-39
NZ_CP017476.1|WP_066093040.1|1434932_1436462_+|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	2.49829e-118
NZ_CP017476.1|WP_066092999.1|1414680_1415430_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl|CDD|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.41109e-98
NZ_CP017476.1|WP_066093023.1|1427271_1428000_-|SDR-family-oxidoreductase	gnl|CDD|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	2.80411e-74
NZ_CP017476.1|WP_082877035.1|1421391_1423716_-|PBP1A-family-penicillin-binding-protein	gnl|CDD|227342	COG5009, MrcA, Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane].	0
NZ_CP017476.1|WP_082877036.1|1433772_1434831_+|LysR-family-transcriptional-regulator	gnl|CDD|176126	cd08435, PBP2_GbpR, The C-terminal substrate binding domain of galactose-binding protein regulator contains the type 2 periplasmic binding fold. Galactose-binding protein regulator (GbpR), a member of the LysR family of bacterial transcriptional regulators, regulates the expression of chromosomal virulence gene chvE. The chvE gene is involved in the uptake of specific sugars, in chemotaxis to these sugars, and in the VirA-VirG two-component signal transduction system. In the presence of an inducing sugar such as L-arabinose, D-fucose, or D-galactose, GbpR activates chvE expression, while in the absence of an inducing sugar, GbpR represses expression. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.96087e-36
NZ_CP017476.1|WP_066092996.1|1413279_1414296_-|TRAP-transporter-substrate-binding-protein	gnl|CDD|270383	cd13665, PBP2_TRAP_Dctp3_4, Periplasmic substrate-binding component of TRAP-type C4-dicarboxylate transport system DctP3 and DctP4; the type 2 periplasmic-binding protein fold. This group includes uncharacterized DctP3 and DctP 4 subfamilies of TRAP Transporters specific to C4-dicarboxylates such as succinate, malate and fumarate. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. This CD also included some eukaryotic homologs that have not been functionally characterized. TRAP transporters are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.67745e-95
NZ_CP017476.1|WP_066093622.1|1425842_1427252_-|mannitol-dehydrogenase-family-protein	gnl|CDD|223324	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism].	3.17212e-136
NZ_CP017476.1|WP_066093005.1|1416558_1418349_+|acyl-CoA-dehydrogenase	gnl|CDD|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.15226e-154

Protein sequences

>NZ_CP017476.1|WP_066093017.1|1423790_1424468_-|SDR-family-oxidoreductase
MPMLSNKRILVTQWREFMGPTLCEVLRAHGATVITSEIPLVEPQAAAAEIGQAGEIDILIANLAIAAPTTPASEVDDDEWRTVFSALVDPLPRLIKAALPAMIQRRSGKILVMGSAAALRGIKRASTYCAARGAQTAYVQAVGLEAASHNVQINLIAQNFVDNPTYFPPEVQANPRFQERLAREVPLGRLVSAREDAEFAAYLCSDNANCFVGQVFPVCGGWVGR
>NZ_CP017476.1|WP_082877035.1|1421391_1423716_-|PBP1A-family-penicillin-binding-protein
MSGNSLRRATAAGLLCSFALFCTVPPASAATFDLPSIDRIVNYTPKLPLQIFTADGVEIAQFGTERRIYVPLSKTPKILQEAVLAVEDARFREHSGIDPKGMARAVVAALTGGRKQGASTITQQLVRTMLLTREFSVERKAKEIMLAFKVEDALSKDRILEIYLNEIFLGQRAYGFAAAAKTYFGKTMDELTTAEAAMLAGLPQNPYYANPVANMDRAIKRQRVVLERMKTTGAISEVQWKAARDEKITLRTPGEKDLHAPHVAEMARRIVVERYGTEAYSSGIRVTTSLMADDQRAAYAAVQRGVLSYDRRGAWRGPEGFEELPDNNNPDLASLAAEALKDHSDDDTLRAAIVLKANSKEIAVQLSTGERVTLSGSGIRWARAGLKSKAKKELSLQRGSVVRVVQSGQKGSPTEWEISQWPEVEAALVSMDSKTGRVRALVGGFDQSRQPFNHVTQAWRQPGSSFKPLLYSAALEERVMPGSLIDDLPYTAANGWSPSNSHAGGESPITLREALAKSSNLVSVRVLDHVGVARARDWVTRFGLDAARQPSNLTLALGTGSVTPLQMVRAYATLANGGWRVSPVVVEKITDAQGKVLFEEAAPENLTEDNRAIPARNAYVMSSLLNDVTRYGTGARAQAQLKRRDIYGKTGTTDNAVDAWFTGYHPTLATAVWMGYDKPRSLGSSESGSRAALPIWIDYMDSALKKTPFTPLGSPPPGLVRENDDWLYAEWKNGGSVARLSDEDGVQYAPEPGRFLPNIPDWARALISSGPRNP
>NZ_CP017476.1|WP_066093619.1|1420526_1421303_+|SDR-family-oxidoreductase
MSQTPPHATPIALVTGGSRGLGRNTALHLARKGSDVVLTYRSQKAEADEVVAQIASLGRRAVALSLDVAQTTSFPAFADSLGEALQRGWRRERFDHLVNNAGTGLHARFVETTEAQLDALYSVHVKGVFFLTQALLPLMNDGGRIVNLSSGLARFTLPGSSAYGSMKGAVEVLTRYMARELGPRGIAVNVVAPGAIETDFNGGAVRDNPQLNLQIASSTALGRAGQPDDIGPMIASLLQPDNRWINAQRIEASGGMFL
>NZ_CP017476.1|WP_066093011.1|1419464_1420415_-|LysR-family-transcriptional-regulator
MSLTQRLEVFARVAELSSFTQAAEQLGLPRATVSNAIQQLENQLGTRLLHRTTRRVQLTQDGLLCFERCKDVLSDLDELQSLFQHPDGGSLKGRVRIDMSSGMARNTVMPRLPDLLAQHPHLTLEVSSTDRLVDLVREGFDCVLRAGQLTDSGLVARPLGHMSMVNCASPAYLKHHGTPQALTDLAQHKLVHYSPTLGAPPTGFEYADAEANAALPMTGAITVNSSEAYTAACLAGLGLIQAPLVGVVELIDQGRLVPVLPSWRPRAMPVTLLYAHRRNLPKRVRVVMDWLARVMAEQLAVTNKKPPASGGFPESD
>NZ_CP017476.1|WP_066093008.1|1418474_1419458_+|nitronate-monooxygenase
MTTRQRAPLPPVLQKIKFPVIGSPLFIISNPKLVIAQCKAGVVGSMPALNARPAAQLDEWLAEITEALAAHDKANPDNPSAPFAINQIVHKSNDRLEQDMALCEKYKVPIIITSLGAREDVNKGVQSWGGVVLHDVINNVFAHKAIEKGADGLIPVAAGAGGHASVKSPFAMVQEIREWFDGPIALSGSIASGGAVLAAQAMGADFAYIGSAFIATEEAHAVDGYKAMITQSDSDDIVYSNFYTGIHGNYLKGSIEAAGMDPNNLPDSDPSKMNFSTGEGANAAKAWKDIWGCGQGIGAIKEVMPAADLVARFKREYAEAKARICGG
>NZ_CP017476.1|WP_066093005.1|1416558_1418349_+|acyl-CoA-dehydrogenase
MSYTAPLKDMLFNIEHIARIDQVAALPGFEDAGLETAQAVLEECAKLNEGVVAPLNWEGDKNPSSFKEGKVTTTPGFKDAYKQFAEGGWQGLQHPASFGGQGLPKTIGAACIEMLNSANMSFALCPLLTDGAIEALLTAGSDDLKSIYLEKLVSGEWTGTMNLTEPQAGSDLAAVRSRAEPQPDGTYKVFGTKIFITYGEHDMAENIVHLVLARVTGAPEGVKGISLFVVPKFMVTADGSLGDRNDVHCVSIEHKMGIKASPTAVLQYGDNGGAVGYIVGEENRGLEYMFIMMNAARYAVGVQGIAVAERAYQKAVGYAKDRVQSRPVDGSMSAAAPIIHHPDVKRMLMTMRASVEGCRAMASVAAAAYDAAHHHTDADVRKQNAAFYEFLVPLVKGYSTEMSLEMTSLGVQVHGGMGFIEETGAAQHYRDAKILTIYEGTTAIQANDLVGRKTARDGGAGAKAIAAQIEKTEAELTKRGSAQSLAVAKRLTAARLAFVDVVEFIAANTRSNPNAAFAGSVPYLLLAGNLMAGWQLARSLLVAEDQLAAGVDAAFMQSKITTARFYADHILSRAPGVRDAIVEGAESVTALAAEAF
>NZ_CP017476.1|WP_066093002.1|1415550_1416483_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MTSLVIAEHDNASIKGATLNTVTAAAACGGDVHVLVAGHNAGEAAKAAAAIAGVAKVIHADAAYLEHGLAENMAAQVLAIASNYSHILFPATASGKNIAPRVAAKLDVGQISDITKVDAADTFERPIYAGNAIATVQSMDATKVITVRTTGFDPAAATGGSASVETAEAVADSGKTTFVGSEIAKSDRPELTAAKVIVSGGRALGSSEKFDEVMTPLADKLGAALGASRAAVDAGYAPNDWQVGQTGKIVAPQLYIACGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLEADLFVAVPELVKSL
>NZ_CP017476.1|WP_066092999.1|1414680_1415430_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MKVIVPVKRVVDYNVKVRVKSDGSGVDIANVKMSMNPFDEIAVEEAVRLKEKGVATEVIAVSCGDAKCQETLRTAMAIGADRAILVETTEELQPLAVAKLLKALMDKEQPGLVILGKQAIDDDCNQTGQMLAALADLPQATFASKVEVADGKASVTREVDGGLETLSVTLPAIITTDLRLNEPRYVTLPNIMKAKKKQMDTVKPEDLGVDVAPRIKTLKVSEPPKRGAGIMVPDVATLVDKLKNEAKVI
>NZ_CP017476.1|WP_066092996.1|1413279_1414296_-|TRAP-transporter-substrate-binding-protein
MKLRYALATAVSATLLASGAASAETVFTVSSWLPPTHTLSTVQKDWCDKLAKESAGSMKCNILPKGVVSAPGTFDAVRDGLADISYTVDGYTPGRFINTQVAEFPFLGDDATATSVAYQRIYDKYFAPLGEHRGVKVLAVFTHGPGIIFNSKMPVTSAAEASSLKFRIGGGNINELSKAMGWNTTLKPAPESFELLSTGVMDGTFFPDESIASFKLSMVKHATTFPGGLYNTSFVFMMNQDKYKALSAADKAVVDKLSGEPAARMFGEGWDKVDAASRDGAQKAQGVARIMADKAFVKAVADKQESLETRWAAAAQAKGLKDPKGALAEFRAEIAKVK
>NZ_CP017476.1|WP_066093616.1|1412698_1413205_-|TRAP-transporter-small-permease
MPKHLDKLLNRTTGLTAATALFSLMWLTLIDVVGRKFFNNSVPGGLELTEILMVIVIFSALPLVSWRNEHVVFDSLDAFIPHWLKSTQMRLVHLISGAVFGFLARLMAMRAERFAEYGDTTVHLQLSIAPVAWIMTALLVVTALVHFLFMFKPNMSANHENSASGAQS
>NZ_CP017476.1|WP_066093020.1|1424874_1425816_-|helix-turn-helix-transcriptional-regulator
MSVIDRNRSIPRQLKPELEHDYARSPDLGYEAPDTTGFVRCLSHGFPTPLARWHCHDEYELHLITETSGKVFVGDWIGQFQPGHLVLTGPRLPHNWLSLDTPEGGVALRDLVIQFQHAPLMQSAAHIAELNELLPLLERARHGVEFFGMGERSERHWHRIKQSQGLRRLTAFFDLMSDLAACTDYRLLSSVQLQSDGSDASIDQIHVLVTRITDHLSETHSAAALAAELGMSESRFSRFFRKATGNTFTDFVNRVRISRACQLLMDTDQQITHICYEVGFNNVANFNRRFLESKGLTPSEFRKQSLTRFRGAA
>NZ_CP017476.1|WP_066093622.1|1425842_1427252_-|mannitol-dehydrogenase-family-protein
MLHLGLGSFHRAHQAVYLHELQKTGDRSWTLAGGNIRPDMADTIAALQAAGGAYTLETISPAGEHHYERITSISQVISYTPDLSGLIAQGSKAETKIISFTVTEAGYYLDAKNRLDLDTFADLRSDLDAVRAGQPGTTIYGALTAILRARRAANAGPVTLLNCDNLRHNGERSRGGLLQFLELIGDAELLAWVQTNTTNPNAMVDRITPRPTPDVRERVLAATGVDDPAALMGESFIQWVIEDRFIAGHPAWETVGVEMVKSVDAYEEAKIRLLNATHSCIAWAGTLINYLYIHEGTQNPVIRRLAYDYVTDDVIPVLDTPEAPCPLNLPKYRDVVLDRFANPAIQDTNQRVAMDGFSKMPGFIAPTIRQRLARGEGIESVAMLPALFLAYLKRWHAGKIPYTYQDQAMDPAVAHAMCEAADPIAAFCADAPLWGGLAEDPRLVEAVRRASERVVRFITAHTGVNPEKA
>NZ_CP017476.1|WP_066093023.1|1427271_1428000_-|SDR-family-oxidoreductase
MTPPLQGKVAAVTGAASGIGRASTEALLAAGARVVLIDRDEKALACTCAALGEHAIPLVLDLLDPRQCASLMPEVLARAGQLDVFHANAGLYVGGDLIDAQHDAIDRMLNLNINVVMKNVRDVLLHMTERKTGDIIVTSSLAAHFPTPWEPVYASSKWAIDCFVQTVRRQVFKHGIRIGAISPGPVITSLLADWPAEKLEEAKASGSLVEASEIAEVVLFMLTRPRGMTIRDVVMMPTNFDL
>NZ_CP017476.1|WP_066093026.1|1428025_1429072_-|ABC-transporter-ATP-binding-protein
MAYLQLQGIEKFFGDHRAIKGIDLEIKPGEFIVFVGPSGCGKSTLLRLIAGLEHIDGGTLSLEGRDITHLPSSKRDLAMVFQSYALYPHMSVAENMSFALKLAGAPKAEIDEKVKKAADILDLTKYLERTPKELSGGQRQRVAIGRAIVRAPKVFLFDEPLSNLDAALRGQTRIEIAKLHRDLGATTIYVTHDQVEAMTLADRVVVLRDGLIEQVGTPLELYDNPANQFVAQFIGTPQMNILPYKQWSAAIKALAPSAAKEGSIGLRPECVVLGSDASAKVQGKVDVVEALGAETLVYITTNEGAQLVARQSERTPLHMGDTVSADLALDQAHWFDSKGRVVKASAAA
>NZ_CP017476.1|WP_066093029.1|1429212_1430043_-|carbohydrate-ABC-transporter-permease
MARQSTYTPAYAVRSVAAWGVALLLFFPLGWLMLTAFKTELQAIAVPPELFFSPTLENFHEVNERSDYLQYAKNSVITSVLSTIFGLMIAAPAAYAMAFFKGKHDKDILMWMLSTKMMPAVGALVPVYVLAQKSHLLDNPIALIIVFTLSNLPIMVWMLYSQFKEIPREILEAARMDGATLWQEARLVLLPLAMGSLASTGLLCLVLSWNEAFWSLNLTAANGGTLATLIAGYSSPEGLFWAKLSAASFMAIAPIVVFGWFSQKQLVQGLTFGAVK
>NZ_CP017476.1|WP_066093032.1|1430052_1430913_-|sugar-ABC-transporter-permease
MKRTLPRLLMAPAVSTLFLWMIVPLVMTIYFSLIQFNLLQPDQSDFIGLENYEYFMTDPSFGAAIMNTLMLLGSVIGITVVFGVLIALLVNEPLAGRGLVRILLISPFFVMPTVNALLWKNMMMNPIYGVFAQVWIFFGATPIDWLTEVPLFSVILMVSWQWLPFATLIFMTSLQSMDREQLEASRMDGANFFQQFRYLYIPHLGRSVAVVVMIELIFLLSVFAEIYTTTGGGPGDASTNVAYLIFKQALLNFDAGVASAGALFAVVLANIVGIFMIRMVGKNLDK
>NZ_CP017476.1|WP_066093034.1|1431045_1432356_-|sugar-ABC-transporter-substrate-binding-protein
MKFRIASALTAALMSAGLAHAAGTELVIATVNNGHMIEMQKLSGNFEKANPDIKLKWVTLEEGVLRQRVTTDIATKGGQFDVMTIGMYETPIWGKKGWLQELKTDAAYDADDLLPAMRDGLSVDGKLFAAPFYGESSMLMYRKDLADKAGVTVPERPTWIQIRDLAAKMHDPKSGVYGICLRGKPGWGDNMALISTMVNTFGGQWFDMKWQPQLESKPWKDAVTFYVDLLTKYGPPGSAANSFNEILALTNSGKCGMWVDATIAASFVSDPKQSKVADQMAFAQAPTAVTPKGANWLWAWALAVPSGSKKVDAAQKFITWATSKEYIELVGKTNGWATVPTGTRKSTYANPEFVKAARFAPAEKMAIDSANPNDSTLPKSPYVGVQFAAIPEFQAIGTTVGQQMSAALAGQKSIDAALKASQVAAERQMKKAGYYK
>NZ_CP017476.1|WP_066093626.1|1432601_1433459_+|shikimate-dehydrogenase
MSAQFLHQITGSFSQPSGENPTVAMVEAAYRHHGLPWRYINCDVAPADLAAAVSGARAMGWVGFNCSMPHKVAVIQHLDGLAPSAQIIGAVNTVVRNAAGKWIGENTDGKGFVQALREVIDLPGKTALILGAGGAARAVAVELALAGVTRIDVVNRSATQGESLVSLINERTSAQAHFRAWDAVLQIPPGTGVLVNTTSVGLGAPDDELSIDWGSLHAGIVVADAIPNPPRTHLVRTAKAKGCITIDGLGILVNQGAIAFRLWTGVEANRGVMRWALERVLGLAG
>NZ_CP017476.1|WP_082877036.1|1433772_1434831_+|LysR-family-transcriptional-regulator
MPQRHWRSGCTPCTFRADLSGRYGCSGFSLEQTALTSQTDSTGANARYFRQGLRLQHLRIMAALAEVQLVSKVAERLHVTQPAISKQIAEIESALSAPVIYRERNRLFLTDVGQRLAAHAQAVMQQLRRAELELEALSLGASGHLRIGAVTSLSPTLVAKAVVAFKRVAPRVSISVTEGHFISLRPLLERGEVDVVVARVWQPQEVPDLEQSVLTSEPIVVVSGRDHPLAKRRRLQWSDALSWPWILPDKQSVARRAIEAFWAEQGMATPGDVIEAQSLPLSLALMCDLPYLGLFPETLALSHAMRGDLSVLGLRMGGVLAEGRCFWRKGQIEQNAVLRPFLDCLRAVPGRF
>NZ_CP017476.1|WP_066093040.1|1434932_1436462_+|amidase
MDANAPLTALPAVAVIEQFRRGELSPVTLVNASIERIERLNVKINAITATCFDRAREEARASEARYQAGQPKGPLDGLTLGVKDLQPTAQLLTTWGSPKWRNHVPQEDLPMVAALRRAGAIVVGKTNVPEHGAGGNSRNPVWGATGNPFNANLVAGGSSGGSAAALAADLVTLCTGSDTGGSLRLPAGLCGIVGFRPSPGLVPHPTRPLGWSSISVLGPMARNMGDLLLMLRSCMGTDARDPLNRGVSPESFNTTGVLPRLETLRIGYSEDFGGCSVEPDIRAAFRDRIERIAPQVAKCVPVDIPHGDWDRCFDVMRAESFMAGFQDVFDHDPVRLSEDIQANVALGKGFTLGDRAWAHLEQTRIMRAYQAQAAHLDLILSPVAPVTPFVWTQGFPAHIDGVAMDIYYRWLALTYRPSLVGCPALTLPCGLDSQRMPFSLQLLGSLNGDAALLQAAQTLEAFFESHEATRRPRPDLEALKPSTTPLNAMVTHPPESGAVPPSGSVATVV

Crispr_ID: NZ_CP017476_2

• CRISPR_ID: NZ_CP017476_2
• CRISPR_location: 1483056-1483183
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP017476_2

Consensus_repeat	Method
TTCACCGCAGGGCCGCCCCAAGGTGAATCAACCCCCCTCAGGGGG	CRISPRCasFinder

spacers of NZ_CP017476_2

>2.1|1483101|38|NZ_CP017476|CRISPRCasFinder
CAGCGACCCGCGCAGCGGCGGAGCGTGGGGGTCATGGT

CRISPR arrays and Neighbor proteins around NZ_CP017476_2

CRISPR arrays

The CRISPR arrays of NZ_CP017476_2

>merge|NZ_CP017476|2|1483056-1483183|CRISPRCasFinder
TTCACCGCAGGGCCGCCCCAAGGTGAATCAACCCCCCTCAGGGGGCAGCGACCCGCGCAGCGGCGGAGCGTGGGGGTCATGGTTTCACCGCAGGGCCGCCCCAAGGTGAATCAACCCCCCTCAGGGGG

>NZ_CP017476|2|2|1483056-1483183|CRISPRCasFinder
TTCACCGCAGGGCCGCCCCAAGGTGAATCAACCCCCCTCAGGGGG	CAGCGACCCGCGCAGCGGCGGAGCGTGGGGGTCATGGT
TTCACCGCAGGGCCGCCCCAAGGTGAATCAACCCCCCTCAGGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017476.1|WP_066093644.1|1483197_1483980_-|DUF2189-domain-containing-protein	unknown	unknown	gnl|CDD|370763
NZ_CP017476.1|WP_066093647.1|1484741_1485485_+|2OG-Fe-dioxygenase-family-protein	unknown	unknown	gnl|CDD|370779
NZ_CP017476.1|WP_082877077.1|1487342_1487792_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|235734
NZ_CP017476.1|WP_066093153.1|1482025_1483027_+|oxidoreductase	unknown	unknown	gnl|CDD|176248
NZ_CP017476.1|WP_066093159.1|1485512_1485854_-|DUF1232-domain-containing-protein	unknown	unknown	gnl|CDD|225876
NZ_CP017476.1|WP_066093165.1|1487961_1488741_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|180796
NZ_CP017476.1|WP_066093641.1|1478692_1479718_-|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270410
NZ_CP017476.1|WP_066093168.1|1488759_1489440_-|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|223638
NZ_CP017476.1|WP_066093136.1|1474529_1475264_-|transglutaminase-family-protein	unknown	unknown	gnl|CDD|224224
NZ_CP017476.1|WP_066093139.1|1475472_1476228_-|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224051
NZ_CP017476.1|WP_066093162.1|1486038_1487223_-|acetyl-CoA-C-acyltransferase-family-protein	unknown	unknown	gnl|CDD|181625
NZ_CP017476.1|WP_066093142.1|1476275_1477379_-|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP017476.1|WP_066093151.1|1481772_1482033_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_157559245.1|1484190_1484613_-|hemerythrin	unknown	unknown	gnl|CDD|179353
NZ_CP017476.1|WP_066093145.1|1477391_1478576_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|226960
NZ_CP017476.1|WP_082877076.1|1473184_1473637_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066093148.1|1480038_1481751_+|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|236235
NZ_CP017476.1|WP_066093171.1|1489436_1489925_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|200361
NZ_CP017476.1|WP_066093175.1|1489948_1490575_-|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NZ_CP017476.1|WP_082877039.1|1473649_1474423_-|DUF1223-domain-containing-protein	unknown	unknown	gnl|CDD|369071

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017476.1|WP_066093644.1|1483197_1483980_-|DUF2189-domain-containing-protein	gnl|CDD|370763	pfam09955, DUF2189, Predicted integral membrane protein (DUF2189). Members of this family are found in various hypothetical prokaryotic proteins, as well as putative cytochrome c oxidases. Their exact function has not, as yet, been established.	1.42936e-31
NZ_CP017476.1|WP_066093647.1|1484741_1485485_+|2OG-Fe-dioxygenase-family-protein	gnl|CDD|370779	pfam10014, 2OG-Fe_Oxy_2, 2OG-Fe dioxygenase. This family contains 2-oxoglutarate (2OG) and Fe-dependent dioxygenases. It includes L-isoleucine dioxygenase (IDO).	6.06358e-84
NZ_CP017476.1|WP_082877077.1|1487342_1487792_-|histidine-phosphatase-family-protein	gnl|CDD|235734	PRK06193, PRK06193, hypothetical protein; Provisional.	2.58535e-29
NZ_CP017476.1|WP_066093153.1|1482025_1483027_+|oxidoreductase	gnl|CDD|176248	cd08288, MDR_yhdh, Yhdh putative quinone oxidoreductases. Yhdh putative quinone oxidoreductases (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_CP017476.1|WP_066093159.1|1485512_1485854_-|DUF1232-domain-containing-protein	gnl|CDD|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	1.71561e-17
NZ_CP017476.1|WP_066093171.1|1489436_1489925_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|200361	TIGR04110, hypothetical_protein_VSWAT3_12502, heme utilization protein HutZ. Members of this family are heme utilization proteins, typically designated HutZ. They are members of the PPOX family (pfam01243) and, except for the lack of an N-terminal extension, are closely related to one form of heme oxidase (1.14.99.3), HugZ (TIGR04109). Members typically are found in a three-gene operon with radical SAM enzyme HutW and a protein of unknown function, HutX.	8.66995e-17
NZ_CP017476.1|WP_066093641.1|1478692_1479718_-|amino-acid-ABC-transporter-substrate-binding-protein	gnl|CDD|270410	cd13692, PBP2_BztA, Substrate bindng domain of ABC glutamate/glutamine/aspartate/asparagine transporter; the type 2 periplasmic binding protein fold. BztA is the periplamic-binding protein component of ABC transporter specific for carboxylic amino acids, glutamine and asparagine. The BZtA domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.25154e-122
NZ_CP017476.1|WP_066093168.1|1488759_1489440_-|RluA-family-pseudouridine-synthase	gnl|CDD|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	5.94165e-70
NZ_CP017476.1|WP_066093136.1|1474529_1475264_-|transglutaminase-family-protein	gnl|CDD|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	1.3573e-10
NZ_CP017476.1|WP_066093139.1|1475472_1476228_-|amino-acid-ABC-transporter-ATP-binding-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.50401e-159
NZ_CP017476.1|WP_066093162.1|1486038_1487223_-|acetyl-CoA-C-acyltransferase-family-protein	gnl|CDD|181625	PRK09051, PRK09051, beta-ketothiolase BktB.	0
NZ_CP017476.1|WP_066093142.1|1476275_1477379_-|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	8.97492e-67
NZ_CP017476.1|WP_157559245.1|1484190_1484613_-|hemerythrin	gnl|CDD|179353	PRK01917, PRK01917, cation-binding hemerythrin HHE family protein; Provisional.	4.68461e-21
NZ_CP017476.1|WP_066093145.1|1477391_1478576_-|ABC-transporter-permease-subunit	gnl|CDD|226960	COG4597, BatB, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	6.22349e-149
NZ_CP017476.1|WP_066093165.1|1487961_1488741_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|180796	PRK07023, PRK07023, SDR family oxidoreductase.	4.64866e-78
NZ_CP017476.1|WP_066093148.1|1480038_1481751_+|long-chain-fatty-acid--CoA-ligase	gnl|CDD|236235	PRK08314, PRK08314, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP017476.1|WP_066093175.1|1489948_1490575_-|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	1.80885e-32
NZ_CP017476.1|WP_082877039.1|1473649_1474423_-|DUF1223-domain-containing-protein	gnl|CDD|369071	pfam06764, DUF1223, Protein of unknown function (DUF1223). This family consists of several hypothetical proteins of around 250 residues in length which are found in both plants and bacteria. The function of this family is unknown. Structurally it lies in the Thioredoxin-like superfamily.	2.11239e-59

Protein sequences

>NZ_CP017476.1|WP_066093153.1|1482025_1483027_+|oxidoreductase
MFKALLINKTDDAGYTCALTEVEESQIPGQGDVTVAVEWSTINYKDGLAITGKSPVVRSFPLVPGIDFAGTVTASEHPRWKKGDRVVLNGFGVGESHWGGLAQMARVKGDWLVALPDALSTRDAMAIGTAGYTAMLCVQALQRHWTEAGMDAGSGEVLVTGAGGGVGGVAIALLSAMGHKVVASTGRLEESDYLKSLGAAEVIDRSALSAPGKPMQKERWIGVVDSVGSHTLANACASTRYGGAVAACGLAQGMDFPASVAPFILRGVTLYGIDSVMAPLAKRESAWQQLARDLDRGKLEAITQEVSLAEALTAGPAILAGQVRGRLVVNVNA
>NZ_CP017476.1|WP_066093151.1|1481772_1482033_+|hypothetical-protein
MPLKDHFLRRSLWRLWQPRRGLFWLMLAFNALSSGLAWWLHLAQPSGTLLVVVTLLALTNTLIGWWLLLILWREGADTNSGEKKHV
>NZ_CP017476.1|WP_066093148.1|1480038_1481751_+|long-chain-fatty-acid--CoA-ligase
MNHAEQVPAVPERAHHRFWPKRLPHSIQTPRTSMWFNLEVSAQRYPDKPALVFFDQSVSYSELKHQAERVASHLQAKGVKAGDRVILLMQNCPQWIASYYGILRANAVVVPVNPMNRAEELKHYITDPDVRVAISAADLAGELAKASEALPEAQRLQHLLVTHYTDAVGAQPEVPSTWVAWLEARHPQPTLSAGDVSDWSEAMACTQALLPHDRAPEDLCVLPYTSGTTGLPKGCMHTHASMMHNTVAASLWGNGSSENTALLVVPLFHITGMVTGMHTGIYLGATTVLMPRWDRDLAGQLISTWRVTSWTNIPTMVIDLLASPHFNQYDLTSLAYIGGGGAAMPQAVAQRLQDAYGLKFAEGYGLTETAAPSHSNPPDAPKQQCLGVPFIGVDSRVIDPDTLKEMPMGEAGEIIMRGPSVFSGYWKRPDATEAAFVEFEGQRYFRSGDLGRVDEDGYFFITDRLKRMINASGFKVWPAEVEALMFRHPAIAEACVIGTQDDYRGESVKAVVVLRAEARGQVSEQDIVDWCRENMAVYKCPKVVQFVEALPKSGSGKVMWRLLQEKEADA
>NZ_CP017476.1|WP_066093641.1|1478692_1479718_-|amino-acid-ABC-transporter-substrate-binding-protein
MKSLNLSLAFAAAAATMVSVPAHAASKTVDAIKARGELVCGVNTGLAGFSQADSSGNWSGLDVDFCKAVAAAVLSDASKVKYVPLNAQQRFTALQSGEVDILSRNTTGTLSRDASLGLHFVGTWFYDGQGFMVKKGKVKNAKQLNGAAVCVQSGTTTEKNLTDFARANKIKITPVVFEKVEAATGAYFSGRCQAYTTDASGLASTRSKEAKVPADHEILSDLISKEPLGPMVRRGDDEWLAINKWVLNGLIEAEEYGIKQGNVVEMKKSSDPQVGRMLGVTEDLGKHLGLDKEWLARSIAATGNYGEIFERNVGPKTPLNLPRGKNNLWNNGGLMYAPPLR
>NZ_CP017476.1|WP_066093145.1|1477391_1478576_-|ABC-transporter-permease-subunit
MIEARPVPKKKSRSISWNSREGRSVIYQVVAIASIAGFLWLLVTNTLENMRRRGIQSGYDFMSQPFGFDVSETLIPYDVMSTYWTAFGIGLANTLKVAIIGIVLATLLGTLLGIGRFSTNFLVRKICYVYVEIFRNIPVYLQLLIWYIIFTETLPAFDDAWEIGNTFLSKGGFAFPWPVWKLGQSLALIGVLLGLAGSYFYARSAQRHFDKTGQRRPVLPVTLAIIIGLAVLGWLAGGAPSEWSLPEKGIFQVEGGTKFSPEFLSLLVGLVLYTASFIAEIVRSGIASVSLGQHEAAASLGLTKSMAMRLVALPQALRVIIPPLTSQYLNLTKNSSLAVAIGYPDLVSIANTSLNQTGRAIEALSIVMAVYLTLSLITALLMNWFNASSAIQER
>NZ_CP017476.1|WP_066093142.1|1476275_1477379_-|amino-acid-ABC-transporter-permease
MQDTFQSIAPRPVPGSSSGAVLWLKTNLFSSPINSIVTLFMLAVVLFAVSQAAGWSITNAVFGADLVACNKARGLGACWGVIAEKGRLILLGLYPQEEQWRPITATSLMLGVVALSCMPNFWNKSLLIMWPAMLAVYFTLMKGGVFGLVAVSTDQWGGLPLTVMLTVISMTLAFPLAIMVALGRRSQMPAIRTLCTLYVELIRGVPLITILFMASFMLPLFMPAGTNIDVLIRVVVGITLFSAAYMAEVVRGGLQALPKGQTEAAATLGMTFWQTQGKIVLPQALTTVVPSLMNTFIGMFKDTSLVTIVSLYDLTGAVGLALNSDADWRPFKMEGLFFIAAIYFAFCFAMSRYSLWVEKRTAVSKSR
>NZ_CP017476.1|WP_066093139.1|1475472_1476228_-|amino-acid-ABC-transporter-ATP-binding-protein
MSNTDAPIIQFENVNKWYPSNGYHVLRDINLSFAKGEKVVICGPSGSGKSTLIRCINALEEYQEGKIIVDGTVVGDDVKGVDRVRREVGMVFQQFNLFPHLTVLENLILSPTWVAKMPRNEAIEKAMAQLERVRIAEHADKYPLQLSGGQQQRVAIARSLCLTPKIMLFDEPTSALDPEMIKEVLDVMIGLTDQGMTMLCVTHEMGFAKAVADRVIFMDQGQVVEQNTPEEFFNNPQNERSQDFLSKILGH
>NZ_CP017476.1|WP_066093136.1|1474529_1475264_-|transglutaminase-family-protein
MTPHTEALSSPSPLLDFEHPEIQRLIRDRRWLSLSEHERTGRIYDFVRNEIAFGYNERDNLPASRVLADGMGQCNTKGTLLMALLRATGIACRLHGFTIDKALQKGAVTGMAYHLAPAEIVHSWVEVQVDGQWLNLEGFILDQPYLHALQQRFPEARSFSGFGAATPNLQSPAVEWRGTHTYIQKAGICQDLGVYVNPDSFYAQQGGNLSGVKSWLYRHIIRKGMNRNVARIRLGSAPPARGQI
>NZ_CP017476.1|WP_082877039.1|1473649_1474423_-|DUF1223-domain-containing-protein
MNTRHSCRSLRSRGAAMALAAGLLLAPLAQAAVCEATSGAKPPMVVELYTSEGCSSCPPADLWLSTLNDQPGILPLAFHVNYWNHLGWQDRFATPATTQRQHQVRAVQKGKYVYTPQVVLNGQDHRGWRGETPATLLMAVQTNQASTPSLKLVREGRRVTAAVGAIGGASTLAGYWAVLQDGLVSQVTRGENAGETLTHDHVVSLYQPVSAWTASEPRRLQLDLPEGPQFDALRVAFVVTRPGLVQPVQGVVLQCPA
>NZ_CP017476.1|WP_082877076.1|1473184_1473637_+|hypothetical-protein
MWSIALAVLPDLGHMLPVTGWAMATLSSADWWQYATASPGQEPPMPEAVGLWAHHLHCVLHSALSAAAVTVLVWWRWRIFWMPLLGWWLHIVIDVFTHSAEFFPSPVLYPLTYWGFDGWAWNQPGALLLNYGALVGVWVWLIRARMFGVR
>NZ_CP017476.1|WP_066093644.1|1483197_1483980_-|DUF2189-domain-containing-protein
MPETQEPEHYGPAVFALKLAQLKPSDPLNWLKLGWADFKRCPRIGLFYGVCFFIMGHALLAVFQNAPAYVLALSAGFLLMGPFLCLGLYDASKAMQTHSHRPSLRASLVAWRPTKGTMGIFAGVLLILELLWGRASLVVFAVTFNTMPTTDHLLAQLLNPENLSFLITYTIVGGLFATLIFVTSVISIPMIMDRQTDAVSAGLTSIRASLQNPGVMFIWGALITLLIGLAMLPYFLGLLIVGPVIGHATWHAYRHIVPVE
>NZ_CP017476.1|WP_157559245.1|1484190_1484613_-|hemerythrin
MEFDMKTPTIEWTDALRLDFDPMDNAHRTFVTLLAIAQTADDAALAPSWQAVIKHTQQHFACEDHWMRESHFANASNHGLQHRLVLNVMREGLAMAQAGDKQALRAMTHELASWFVKHTQSLDAALALHMRRFPALAAEA
>NZ_CP017476.1|WP_066093647.1|1484741_1485485_+|2OG-Fe-dioxygenase-family-protein
MSTSEFRPPYMPLTERDHALKERGFALLNAAETAQWLGADEADLARLHAIWDDLPSDDYMKDGGRYRRRRHSCFEVEGGAVTQVAHRAHWQPLQYNALHGGMQRWFEPMDEGVVASPVWKRLLAGVGAAATALHGARPWFVEAHPFRIDTTDGIGRPTPEGAHRDGVDLVAVFMVARHQIKGGESRVFEAEGPNGQRFTLREPWSLLLLDDARVIHESTPIQPMVDGEMGWRDTLVLTYRRGGFQGD
>NZ_CP017476.1|WP_066093159.1|1485512_1485854_-|DUF1232-domain-containing-protein
MWKRLTMVWIAVKGDALRLWYALGHPDSPPWLKAGAAAMALYLVSPIDLIPDVLPVIGVMDDLILIPLALRWLLSRLPAHIRQYAEERSRGGSGTRRAAQPADEVRSSNSRLR
>NZ_CP017476.1|WP_066093162.1|1486038_1487223_-|acetyl-CoA-C-acyltransferase-family-protein
MSREVVVVAATRTAIGTFGGSLKDSPPTELAALVVKEALARAAVDGKDVGHVVFGHVVNTEPKDMYLSRVAAVNGGCGEGTPAFNVNRLCGSGLQAIVNASQSILLGDTDIAIGGGAECMSRAPYASLATRFGARMGDTKMIDMMIGALHDPFHNIHMGVTAENVAAKYGITREMQDALAVESHNRAQRATESGRFKDQIVPVMLKSRKGEVAWSTDEHFRPDCKPEDMAKLKPVFVKENGTVTAGNASGINDAAAAVVLMEAGVAKARGAKAMARLVGYAHTGIDPKIMGVGPISATQAVLKRTGLTVNDLDVIEANEAFAAQACAVTKELGLDPAKVNPNGSGISLGHPIGATGALITVKALYELERVQGRYALVTMCIGGGQGIAAIFERV
>NZ_CP017476.1|WP_082877077.1|1487342_1487792_-|histidine-phosphatase-family-protein
MRHAQTVSGTGDPANFRIGDCSTQRNLSEAGREQARRVAVAFQREGVVPDEVRSSAWCRCVDTAELAFGRHTVWAPINSFFQQNSGERQTREALQSLQQHKAPRNLVLVTHQVNISALTGNFTVMGEMLLARPEHASPHQLEVLARQTF
>NZ_CP017476.1|WP_066093165.1|1487961_1488741_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTTTPQHLTILTGASRGMGLAMAEQLLAPNRLLLCISRKSNDDLTRAAATQGAPLTQWQQDLADSQGAAERLQDWLAAQAPEGLASATLINNAGVITTIGPLEAAPAEGLINALRVGLEAPMLLTAAFLRVTGDWVHAGWRGPRKVLNISSGLGRHAMAGQASYCAAKAGMDHFTRGSALDEAEKPFGAKLVSLAPGVIDTDMQAQLRAGDPAHFPGLSRFIELKEKGQLSSPQQAAQQVLAWLDRKDFGSQPVADVRD
>NZ_CP017476.1|WP_066093168.1|1488759_1489440_-|RluA-family-pseudouridine-synthase
MTGNHPGLEVLFADNHLLVLNKPAGLLAVPGRGPDKQDCLSARAQAAWPDALVVHRLDMATSGLVVMARGIDAQRSLSLAFEKRRVYKRYVAVVCGALLNPLPDNDWGTIDLPLLLDWLNRPRSIVSLETGKPSQTRWRLSPQLPAENPQAHTGIATRVELEPITGRSHQLRVHLQAIGHPIVGDTLYAPLDAPAKADRLLLHAQAIEVPHPFTGERLLFESPCPF
>NZ_CP017476.1|WP_066093171.1|1489436_1489925_-|pyridoxamine-5'-phosphate-oxidase
MASENGLTRALSDLFASQRTGALGTLSSDGDAFVSRVPFAIETETASLVIHVSALASHTGNLLRHPRASLMISRAETAGEPVHALPRVTIDVQAEAFDSNSADIQHLRSSYLARFPEAEPMTQLGDFRFIRLRPLRARQVAGFGAARNISVETLAQAMGAAI
>NZ_CP017476.1|WP_066093175.1|1489948_1490575_-|OmpA-family-protein
MQPSTLTPLHFPKRATLAAAALTTALLSGCAPATRVTLLPQADGHPSAVEVTTSKGSQLVAQPYQVAEVTKAGAVEVVPTTAEEVRKAHPQLIALLPAAPDRFVLEFEPGSSDLTAASQARLPEVITKAQARAGGEIVVTGHTDRQGTLEANDALSLKRAQAVRDLLIGQGFQPELIQAVGRGEREPTVPTDDEVIEPRNRRAEVVVR

Crispr_ID: NZ_CP017476_3

• CRISPR_ID: NZ_CP017476_3
• CRISPR_location: 2046638-2046741
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP017476_3

Consensus_repeat	Method
GCACCTTGGAGCGGTCCGGCGGTG	CRISPRCasFinder

spacers of NZ_CP017476_3

>3.1|2046662|56|NZ_CP017476|CRISPRCasFinder
AGCTTTTGCCCCCATGCTCCGCCGCTTTGCGCGTCGTGGCCCCCGAGGGGGCCAGG

CRISPR arrays and Neighbor proteins around NZ_CP017476_3

CRISPR arrays

The CRISPR arrays of NZ_CP017476_3

>merge|NZ_CP017476|3|2046638-2046741|CRISPRCasFinder
GCACCTTGGAGCGGTCCGGCGGTGAGCTTTTGCCCCCATGCTCCGCCGCTTTGCGCGTCGTGGCCCCCGAGGGGGCCAGGGCACCTTGGAGCGGTCCGGCGGTG

>NZ_CP017476|3|3|2046638-2046741|CRISPRCasFinder
GCACCTTGGAGCGGTCCGGCGGTG	AGCTTTTGCCCCCATGCTCCGCCGCTTTGCGCGTCGTGGCCCCCGAGGGGGCCAGG
GCACCTTGGAGCGGTCCGGCGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017476.1|WP_066094646.1|2041286_2042987_+|thiamine-pyrophosphate-binding-protein	unknown	unknown	gnl|CDD|181285
NZ_CP017476.1|WP_066094673.1|2052833_2053070_-|DUF904-domain-containing-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_082877116.1|2055330_2056653_+|cobyrinate-a,c-diamide-synthase	unknown	unknown	gnl|CDD|234896
NZ_CP017476.1|WP_066094652.1|2043897_2044548_+|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP017476.1|WP_066094658.1|2046742_2047825_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239492
NZ_CP017476.1|WP_066094676.1|2053451_2055287_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|226664
NZ_CP017476.1|WP_066094670.1|2051137_2051953_-|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP017476.1|WP_066094667.1|2050598_2051108_+|RraA-family-protein	unknown	unknown	gnl|CDD|236487
NZ_CP017476.1|WP_066094632.1|2035554_2036274_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP017476.1|WP_066094637.1|2036988_2037207_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066094635.1|2036336_2036825_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_CP017476.1|WP_066094629.1|2034395_2035403_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270398
NZ_CP017476.1|WP_066094682.1|2056649_2057462_+|cobalamin-binding-protein	unknown	unknown	gnl|CDD|238564
NZ_CP017476.1|WP_066094643.1|2040047_2041265_+|MFS-transporter	unknown	unknown	gnl|CDD|341031
NZ_CP017476.1|WP_066094640.1|2037737_2039849_+|DUF4347-domain-containing-protein	unknown	unknown	gnl|CDD|372982
NZ_CP017476.1|WP_082877102.1|2047851_2049678_-|hypothetical-protein	unknown	unknown	gnl|CDD|143636
NZ_CP017476.1|WP_066094655.1|2044522_2046580_-|hypothetical-protein	unknown	unknown	gnl|CDD|173804
NZ_CP017476.1|WP_066094649.1|2043124_2043826_+|hypothetical-protein	unknown	unknown	gnl|CDD|197715
NZ_CP017476.1|WP_066094897.1|2052453_2052822_-|cell-division-protein-ZapA	unknown	unknown	gnl|CDD|377476
NZ_CP017476.1|WP_066094664.1|2049842_2050340_-|hypothetical-protein	unknown	unknown	gnl|CDD|349489

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017476.1|WP_066094646.1|2041286_2042987_+|thiamine-pyrophosphate-binding-protein	gnl|CDD|181285	PRK08199, PRK08199, thiamine pyrophosphate protein; Validated.	0
NZ_CP017476.1|WP_066094652.1|2043897_2044548_+|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	3.66032e-35
NZ_CP017476.1|WP_066094658.1|2046742_2047825_-|phosphatase-PAP2-family-protein	gnl|CDD|239492	cd03398, PAP2_haloperoxidase, PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles.	5.60686e-17
NZ_CP017476.1|WP_066094676.1|2053451_2055287_+|TonB-dependent-receptor	gnl|CDD|226664	COG4206, BtuB, Outer membrane cobalamin receptor protein [Coenzyme metabolism].	1.86433e-141
NZ_CP017476.1|WP_066094670.1|2051137_2051953_-|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	4.77847e-24
NZ_CP017476.1|WP_082877116.1|2055330_2056653_+|cobyrinate-a,c-diamide-synthase	gnl|CDD|234896	PRK01077, PRK01077, cobyrinate a,c-diamide synthase.	3.44392e-174
NZ_CP017476.1|WP_066094632.1|2035554_2036274_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	6.73499e-51
NZ_CP017476.1|WP_066094667.1|2050598_2051108_+|RraA-family-protein	gnl|CDD|236487	PRK09372, PRK09372, ribonuclease E inhibitor RraA.	1.02777e-85
NZ_CP017476.1|WP_066094635.1|2036336_2036825_+|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	2.73846e-20
NZ_CP017476.1|WP_066094629.1|2034395_2035403_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270398	cd13680, PBP2_TRAP_SBP_like_4, Uncharacterized substrate-binding protein of the Tripartite ATP-independent Periplasmic transporter family; the type 2 periplasmic-binding protein fold. This subfamily includes uncharacterized periplasmic substrate-binding proteins similar to TRAP transport systems such as SiaP (a sialic acid binding virulence factor) and TeaA (an ectoine binding protein). TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.08144e-107
NZ_CP017476.1|WP_066094682.1|2056649_2057462_+|cobalamin-binding-protein	gnl|CDD|238564	cd01144, BtuF, Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	2.88804e-60
NZ_CP017476.1|WP_066094643.1|2040047_2041265_+|MFS-transporter	gnl|CDD|341031	cd17478, MFS_FsR, Fosmidomycin resistance protein of the Major Facilitator Superfamily of transporters. Fosmidomycin resistance protein (FsR) confers resistance against fosmidomycin. It shows sequence similarity with the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. This FsR family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.92772e-24
NZ_CP017476.1|WP_066094640.1|2037737_2039849_+|DUF4347-domain-containing-protein	gnl|CDD|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	4.30701e-54
NZ_CP017476.1|WP_082877102.1|2047851_2049678_-|hypothetical-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.95068e-28
NZ_CP017476.1|WP_066094655.1|2044522_2046580_-|hypothetical-protein	gnl|CDD|173804	cd07478, Peptidases_S8_CspA-like, Peptidase S8 family domain in CspA-like proteins. GSP (germination-specific protease) converts the spore peptidoglycan hydrolase (SleC) precursor to an active enzyme during germination of Clostridium perfringens S40 spores. Analysis of an enzyme fraction of GSP showed that it was composed of a gene cluster containing the processed forms of products of cspA, cspB, and cspC which are positioned in a tandem array just upstream of the 5' end of sleC. The amino acid sequences deduced from the nucleotide sequences of the csp genes showed significant similarity and showed a high degree of homology with those of the catalytic domain and the oxyanion binding region of subtilisin-like serine proteases. Members of the peptidases S8 and S35 clan include endopeptidases, exopeptidases and also a tripeptidyl-peptidase. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The S53 family contains a catalytic triad Glu/Asp/Ser. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	5.14358e-23
NZ_CP017476.1|WP_066094649.1|2043124_2043826_+|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.71102e-06
NZ_CP017476.1|WP_066094897.1|2052453_2052822_-|cell-division-protein-ZapA	gnl|CDD|377476	pfam05164, ZapA, Cell division protein ZapA. ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.	2.44597e-15
NZ_CP017476.1|WP_066094664.1|2049842_2050340_-|hypothetical-protein	gnl|CDD|349489	cd10567, SWIB-MDM2_like, SWIB/MDM2 domain found in SWIB/MDM2 homologous proteins. This family includes Schizosaccharomyces pombe upstream activation factor subunit spp27, Saccharomyces cerevisiae upstream activation factor subunit UAF30, Chlamydiae DNA topoisomerase/SWIB domain fusion protein, Arabidopsis thaliana zinc finger CCCH domain-containing proteins, AtC3H19 and AtC3H44, and similar proteins. S. pombe spp27, also termed upstream activation factor 27 KDa subunit (p27), or upstream activation factor 30 KDa subunit (p30), or upstream activation factor subunit uaf30, is a component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. S. cerevisiae UAF30, also termed upstream activation factor 30 KDa subunit (p30), is a non-essential component of the UAF. It seems to play a role in silencing transcription by RNA polymerase II. The SWIB domain found in Chlamydiae DNA topoisomerase may play a role in chromatin condensation-decondensation, which is characteristic of the chlamydial developmental cycle and not found in any other types of bacteria. AtC3H19, also termed protein needed for RDR2-independent DNA methylation (NERD), is a plant-specific GW repeat- and PHD finger-containing protein that plays a central role in integrating RNA silencing and chromatin signals in 21 nt small-interfering RNA (siRNA)-dependent DNA methylation on the cytosine pathway, leading to transcriptional gene silencing of specific sequences. This family also includes many uncharacterized proteins containing two copies of SWIB/MDM2 domain.	6.66649e-29

Protein sequences

>NZ_CP017476.1|WP_066094655.1|2044522_2046580_-|hypothetical-protein
MNGNGLRWKPLPTGSFTGTRWNRPGEIDGQDPYLVWAEADAFAGYGHHHGSDPLKWLPIVIEIAPGADVAELVRASSHHWLQIPRAYLNLPGLRYCSARVSAHFFEALRQQPVLRALVVRYELGLPVGPHTHALHDPCTVAHANAAPLKGPRPAKTSRREKGLKGPVIGLIDGGLALVNQAFLNPRGPSRVQHFWRQDSCYQGPWPNQNTHGSGDTPLDPQRAGPTPADMGYGHELTASNIRSAMARFTPSGGSLDEAALYRHFQLWDLARPVNHGTHVMSLAAGSGIPHMPVDDAASRCDLVAVQLDWSNIQDTSGGAMNVSVLDGLMYIVSRCAPSAEVVINISWGTLAGPHDGSSILEAAMDQLIELLGKQLQITVPAGNGYQSRTHANDTLAPGTSCPLHWRVLPDDHTQSFLEIWLPDGADQVTIELTPPGASAPLPALRPGQAGIWKGNSNSQARHPLCALIYPQRSALGANGTCALIALAPTFGLEKHVATAPFGVWEVRLRNEGNEHVTFDAYIERDDVALGQHTGARQSYFEDARYDTSGNLGSFTDHANNPTPIRRSGTFNSLSTGQRTVSVGGTRRQADAWNRFARYSPQKPDPDATRPQRPGVKKVPDTLQPSDDNPALWGVLGAASLSGSMARLAGTSSSSPQQARDIINQRTLPGGGSSTAGSATSGPARA
>NZ_CP017476.1|WP_066094652.1|2043897_2044548_+|Crp/Fnr-family-transcriptional-regulator
MPARLLPNPDASSTHIAALGRLGVQRRYRRGALLIQEGDTGDSIYIVLEGRLRAFLGDESGKELTLGVYGPLEYVGEMSLDGGPRSAHVEAVETSLCAVVSREILQRYIAEHPDFAFEIMGRLIRRARLATESARSVALIDVYGRLVLLLNATTDPDADPNSQRRLLQRMTHQQISQHLACSREMVSRLLKDLETGGFIEVRDRWIWLLKPLPARW
>NZ_CP017476.1|WP_066094649.1|2043124_2043826_+|hypothetical-protein
MWTSQDLAFKTSFNPGTSTSTSAGRFAGMDAGLLMRMMDEIDHGMLVIDDQSRLRHANHLARHALATSRFIVCHGQTLMGSSVEFTQQIDHALKHALKGHRQLVALKEPECELTLAFVPLSHALETDTPSVLVLLSRQNACENLAVRMYARTHQLSPSEEQVLISLCKGNTIPEIAESHHVAPSTVRTQVKALRNKTGCHSIRMLMLRVNSLPPMVSALRAIVPMEHNDMALV
>NZ_CP017476.1|WP_066094646.1|2041286_2042987_+|thiamine-pyrophosphate-binding-protein
MNTPRIAGHLLVECLIAQGVTHAFGVPGESYLAVLDGFHAHADRIRLVVNRQEGGASFMAEAQGKLTGRPGICFVTRGPGATNASIGLHTAFQDSTPMILFVGDVASDARDREAFQEVDFASFFGPSTKGMAKRVERIDDPRRIPEYVARAFATAMNGRPGPVVLVLPEDMLTEMVQAEPLPRVEAVQMAPDPEAMTRLHRHLLNAQRPLVIAGGSGWSPQAAIDLQRFAEQWQLPVVNAFRFQDCFDNHHALYAGDMGLGINPALAQRIKDSDVILAVGPRLGEATNGGYVLVEAPVPLQKLLHIHVSAEELGRVYQPVVGVCASMGAATRALKALEPPANVPWAGWVKACQDDYLANVDPANGGVVFPGSIDMPALIHTLQKHLPADAVLTNGAGNFASWLHRFYRYTGWASGAKTQLAPTNGAMGYGVPAGVAASILTGRTVLTIAGDGDFLMNGQELATAVQHGGKTIVLLLNNGTYGTIRMHQEREYPAHVSGSDLNNPDFCRLAEAYGYAAERLTRTSEFEPALQRALANPRGTLIEVMLDPEVITTRGTLSAIRNRAMS
>NZ_CP017476.1|WP_066094643.1|2040047_2041265_+|MFS-transporter
MSLAQPVPLRQDASVIGLVGMAHATSHFSHLLLAPLFPVFIREFGLSYSDVGLLVSLFFVISGVGQALSGFLVDRVGARPVLFAAISCFLVAALVASQVTGYRGLMVVAALAGLGNAPFHPADFTILNHRVSAARLGHAFSAHGLTGNLGWALAPAMLVGITSLANWRTAYLAAAVMYVVVLTVLFWHRDKLLTPVVPQRAANDAGEGALAYLKLPVVWWCFAFFLLSTMTLAVVQSFAPSILQNLHGVGMEQATLTISAYMLCGALGMLVGGFVAAFGQQHGAFSSDRVVALSMSAGALLLLLCAMGWMGGTGTMVALSVTGFAVGIGGPSRDMMIKKATPKGATGRVYGTVYSGLDVGFALSPLIFGQFMDRGWYALTLVGAAVSLALAVYAALGVGRRTRVA
>NZ_CP017476.1|WP_066094640.1|2037737_2039849_+|DUF4347-domain-containing-protein
MSTTESTAGQPIVFILDNVTDYQNTADGLNANFEVHILSADGDALAQMVALLDGRTGLDAIHLISHGDAGVLDLGTLSLSSANLGDHSAALAALGASLSPDGDFLLYGCDVAQGEAGVAFVDALAVATGADVAASNDTTGPAAQGGDAVLEYETGSIEAVTLDDSAFQSSLGADSALPAGLTTSPYVFNGADFQLRIDGSISNADLDHDLVSSMLTGINTDRFALSNIADGTVVSVYMGNSSTLDDRIQIIRGGFVLTQNDNSGDGDNSEDAYLSWTYQAGDIVHATTTGTLERGSYSLYVGTASGPAPIASILDNAPVVTVAQPVYAIVENGVGKGWTDSGGSLTGTLSLANGASLGDLSGLGFAVDGPSFSDDGGNLTAIGQFGNLNLNPQTGVYSYNPNVNTIDALGEGETGIDTFTFNATGVAGDVTSGSFSFSVTGSNDAPVISLDGQGATLVEASGADNAVAGKEVAQIGVLMSDAEGSVGLNTSALESDGWVLIPDTSFMSHEALYGSVQLDLTTGQVTYTLNNALEATQLLNSGDSVVESFHVSVIDGGGLTDRVAVSFEVHGADDGLVMAVDQAPPAATYIDGDGFIQTNYGRTGFLNVSDIDTLISSYDGLTFGLQGGVGDDGGNLSVAGQAGYLHLNTGTGKFDYVGNASIIEQLAEGASITEHFTFSVSDVNGVLDTGVYEVQFVGVHTEA
>NZ_CP017476.1|WP_066094637.1|2036988_2037207_-|hypothetical-protein
MLYNKTPKAWATLAQPSHVGRLAHTLVLMANGRRSLRELSLLTGTDITEEAALLQKAGYLMVQEPAKAQPAD
>NZ_CP017476.1|WP_066094635.1|2036336_2036825_+|PaaI-family-thioesterase
MDTSTLINASQSPPAGFRAVRVGGNFIAHNGPLFARLVEGRLQLGFRVEARHTNPLGICHGGMLATMADMLIPCAAMYRPGEERRFLPTISLQVDYMGAAPLGAWVQGEGEVLRTTRNMLFGQALVLADGQPAMRVSGIFKQGRLVTEGNMEDPLGLMDPAD
>NZ_CP017476.1|WP_066094632.1|2035554_2036274_+|GntR-family-transcriptional-regulator
MSPPPNSRSRVQQVRDQLEDDIVNGRMRPGEQVQIEPLMVRFAVSRTPVREALQQLEISGLVEVLPKRGTFVARVGIPELIHMFEVMAELEAMCARLAARRAPTATLDGIRGALEACEHETASDDANAYYYANELFHSLIYQACGNPFLVQQTLALKNRLKPYRRLQLRMRNRIQQSLAEHREIVRALEAGDPEAAAHAAREHVLIQGQRFNDFISLAGPEQAASAERASLPAGTTQGR
>NZ_CP017476.1|WP_066094629.1|2034395_2035403_-|ABC-transporter-substrate-binding-protein
MTIRLSRHLSTLALAALTALGAAAAHAEVTLKASHQFPGGKGDVRDEMVQMIARDVAAANVDMTIKVFPGSSLVKAQEQWKAMLSGQIDMTSLPLDYASGFHPQFGATLMPGLVKSHAHARRINDSEFLKEIKGIIEKGGVKVLADAWLAGAFAGKDKCIKKPEDVVGLKMRSAGATFSQMWAGAGASIVSIPSSEVYSALQQGVATATDTSSGSFVSFRLYEQVKCITAPGDNALWFMYEPVLISMKSWDKLNDAQKKALMAASKKAEDYFEAESKKLDDKMVETYKANKVEVVTLTDAEAEAWRAVAQKTSYKEFAEKVPGGKELIEKALSVK
>NZ_CP017476.1|WP_066094658.1|2046742_2047825_-|phosphatase-PAP2-family-protein
MSANSGGFSGGFSGGFSGGFSGGFSGGFGANENVGAGALLLNRAALVGPYTGPSLHVREPAFDDPANLALWADGPRVTACFTELIEGLLFKTNNTAKQAKLEYANLQAATLQRKPLVTLRAPRKAQFEKQLDLVAAYADLRPDRASEILAQLPFPLPFWASVIGLHEHRHKKTLQLLDLAFGLAVHVEMRFKHIFAVPRAEAFSPQIQPMIPSPGHGSWPSGHATEAFLTATLIETLLDAASPPGSHNGADSREQLQRLAARIAVNRTVAGLHYPVDSAVGRLLGTALAEFVVARATGGKVHERGFDGRQYEHAGGAPLDFSLHQSLEHGHGYSREARPTSIGQAPLVAWLWKEAVKEWA
>NZ_CP017476.1|WP_082877102.1|2047851_2049678_-|hypothetical-protein
MTRSAPTPTMIPGESESTSLDSLLPPLQSNRVVLVVDLVESVRLMSVNETAVVGQWHNFVQHALTQVLPAHGGRLVKSLGDGMLAEFEVCSQAIQATLKLQRYFDRFNATAEAESQMHLRAGLHVTHLYRDEQDVYGHGVNLAARIASLAEPGETVVTSAVRDAMVDGIDGDVEDMGESYLKHWPEPVRTWRIQPVSTTAFNWRPERREAPATDFRPSIAVIPFEARTPSPEHFVIGELIADGVIAQLARSQNVRVISRMSTTAFRGRGATSGEINDKLDAPFVLSGGYAALGDKVMITAELADTRRGEVVWADRLSGDTMDLMQVESELINKLSSACAHAMLNAEVQRTLVQPLPKLDSNALMLGGITLMHRSTPRDLQRSQQLLEAVAERHKRVAAPWAWLAKWHIIQVVQGLSSDPANAFRRAISIADRALDMEPNSALAMAIKGHALCHLGSDVDGSRQLLQEATQSNPNDPMAWLYSCVWSAMWGRPHDSVTEAENALNLSPLDPQRYYFEMMLATSYLVVGEYEKTAKLCQSSLQKNRYHLPTIRTLVAAQYELGQVEDAQDTFQTLMRLQPSLTLAAYLETGGVSPTRQKVAHALSALGLR
>NZ_CP017476.1|WP_066094664.1|2049842_2050340_-|hypothetical-protein
MATAKKAPAKKAAPAKKAAPAKKAAAPVKKAAPAKKAAPAKKAAPAKKAAPAKKAAPAKKAAPAKKAAPAKKAAAKKAAPAKKRTPNAAFMKAMTPSAALAAIVGSKPLPRTEVTKQVWVYIKKHKLQDELNRRMINADAKLKEIFKKAQASMFEMTKMINEHLK
>NZ_CP017476.1|WP_066094667.1|2050598_2051108_+|RraA-family-protein
MPITSFVPTCDLCDTHKTDDSGAFRVLPPVFRDFGAVRRFGGEVVTVKCFEDNSLVRAAVGSEGLGRVLVVDGGASLRRALLGGNLGAAAASNGWAGVVIDGCVRDVAELHACEVGIRALACIPLPTEKRGEGQAGVAVQIQGVWVRPGDWLYADEDGIVVSAKPLHGG
>NZ_CP017476.1|WP_066094670.1|2051137_2051953_-|sulfite-exporter-TauE/SafE-family-protein
MILEPLLIVELAALGLCTGFLAGLLGIGGGMIMVPFITVILSGRGVSPDLAVKMAIATSMATIIFTSVSSVRAHHKRGAVRWDIVKLLAPGIVIGAALASLGVFALLKGSWLALLFSAFVAFSATQMLLNKKPHAARTLPGPAGLLGAGSAIGFLSGLVGAGGGFVSVPFMTRCNVAIHNAVATSAGLGFPIALANAVGYVVSGQGAANLPAGSMGYVYLPALLVIAIASVLMAPMGVKAAHALPVASLKRVFATILYGLAAYMLYKGLSA
>NZ_CP017476.1|WP_066094897.1|2052453_2052822_-|cell-division-protein-ZapA
MKQIEVQIMGQSYLLACPPGGETALLDAVGKVDTAMCRIRDAGKVKARDRIAVLASLNLAFELSQRESELLAQTSFANSEPAPLGDMGAAVQASVNDPAAQNRAEELIRRLDQTLGSDGQLI
>NZ_CP017476.1|WP_066094673.1|2052833_2053070_-|DUF904-domain-containing-protein
MAEPTPFDQISERVERLLLRHEELQRTNALLLDQVQSLQVERDSLKSRLNAARARIDALLDRLPNTDSAPSAGQEGTE
>NZ_CP017476.1|WP_066094676.1|2053451_2055287_+|TonB-dependent-receptor
MLNSSLRAPLAALPLALLAAFSHAQTAPVPSLPTTVVTATRVAQPITDVVADVTIVDRAAIERSGATGLADVLGRLPGVSLARNGGLGATTSVYVRGAETRFTAVFVDGVRIDSQSTGGASWNAIPLSQVDRIELVRGPAAAVYGSDAMGGVIQIFTRKGEAGFSPSVEVGVGSYGTRKVAASISGQQGVVDYALGVSRETSDGFNAQPESNPDRDGYRNTAFSGSLGWQFNAANRIDVNLLDSDLDAQYDGFSPGNDDRGQSDLQTLGVNWSAEWSDSYSTKLAVTRGRDRYATSPSPYLTDTSVTSYLWQNNWKLGDSQLTAALERREDRLDNASTSPVITERSQNALALGYALRSGAHTLQLNARRDDDSEFGGQSTGSAAYAFGFMPNWRALVSMGNAFRAPTLFQRFSRYGVASLRPETSNNIETGVKYDQGATSFSAIVYRNKVSDLITYVAGPGTCANGTGDYAGCYGNTAKAQYSGLTLAGAQRVGMLAFSGSLDLQNPKDASTGKQLARRAKQAAKLAVSTGVAGWNLGAETEYVGKRFNDARNNERLDGYTLVNFSVSTPVAKDWTLLGRVDNIADTDYETAKGYATAGRTFYVGLKWAPN
>NZ_CP017476.1|WP_082877116.1|2055330_2056653_+|cobyrinate-a,c-diamide-synthase
MLVAAPASGQGKTTVTAALARLHVRAGRRVRAFKSGPDFLDPFWLELATGHPAHNLDLWMTGETDAQARLHDAAQSADLIIVEGVMGLFDGEPSAADLARRFGLHVLAVIDASAMAGTFGALAFGLQHYRPGLPWAGVLANRVASERHADMLQSAVAGDEAVTPSVWLGALMREPKMALPERHLGLQAAHELPDALARLDAAADALSATPLGQMDLAALASWTVAFEPPSQAAAVPPLLAGKTVAIARDAAFSFVYAANLDTLRALGARLTFFSPLANVRVPPCDAVWLPGGYPELHAPTLAANHTTRDSLAEHVEAGRPVWAECGGMMVLFDELVDRAGNPHAMWGLLRGRISMQARLAALGPQRLMLSAGELRGHTFHYSICETPMPVALHTDAMRGGAVAAGEALHQRGALRASYFHAWMPSSPSATAALFLNEDLS
>NZ_CP017476.1|WP_066094682.1|2056649_2057462_+|cobalamin-binding-protein
MKPGPQRIVCLTEETTEWLYLLGQEARIVGISGYTVRPRRAREEKPKVSAFLSAKIDKILALKPDCVFGFSDLQADIAAELIRAGVQVTVFNQRSVDEVFGVLYQVAAMVGCAEEGMRRIVAMERRLAEIRADVLLRQVDGKRRPKVFFEEWDEPHISGIRWVSELLGIAGGDDAFPELANESLGKNRIIADGAEIVRRNPDIIMGSWCGKKFRPEKVAARSGWQSVSAVKNGQLFEIKSADILQPGPAALTDGVEQMHRIVLDWMALHG

Crispr_ID: NZ_CP017476_4

• CRISPR_ID: NZ_CP017476_4
• CRISPR_location: 2443488-2443629
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP017476_4

Consensus_repeat	Method
GAGATGAAGGGCATGGACCAAAGCAAGATGGGCCAAG	PILER-CR

spacers of NZ_CP017476_4

>4.1|2443525|23|NZ_CP017476|PILER-CR
GCACACCTGCTGAATCTGCCGGT
>4.2|2443585|25|NZ_CP017476|PILER-CR
TGGTGGTGCCTCCATGCCCATGGAA

CRISPR arrays and Neighbor proteins around NZ_CP017476_4

CRISPR arrays

The CRISPR arrays of NZ_CP017476_4

>merge|NZ_CP017476|4|2443488-2443629|PILER-CR
GATATGAAGGGCATGGACCAAAGCAAGATGGGCCAAGGCACACCTGCTGAATCTGCCGGTGCGATGAAGGGCATGAACCATGGTGGTGCCTCCATGCCCATGGAAGAGATGAAGGGCATGGACCACAGCAAGATGGGCCAAG

>NZ_CP017476|4|1|2443488-2443629|PILER-CR
GATATGAAGGGCATGGACCAAAGCAAGATGGGCCAAG	GCACACCTGCTGAATCTGCCGGT
GCGATGAAGGGCATGAACCATGGTGGTGCCTCCATGC	CCATGGAAGAGATGAAGGGCATGGA
CCACAGCAAGATGGGCCAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017476.1|WP_066089587.1|2436374_2436791_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066089602.1|2441443_2443294_+|copper-resistance-system-multicopper-oxidase	unknown	unknown	gnl|CDD|273649
NZ_CP017476.1|WP_066089628.1|2452581_2453181_+|DNA-repair-protein-RadC	unknown	unknown	gnl|CDD|178801
NZ_CP017476.1|WP_066089599.1|2440562_2440844_-|CopK-family-periplasmic-copper-binding-protein	unknown	unknown	gnl|CDD|371581
NZ_CP017476.1|WP_066089605.1|2444663_2445173_+|cupredoxin-family-protein	unknown	unknown	gnl|CDD|259873
NZ_CP017476.1|WP_066089581.1|2435551_2436004_-|DUF302-domain-containing-protein	unknown	unknown	gnl|CDD|269820
NZ_CP017476.1|WP_066089575.1|2434929_2435175_-|DUF2933-domain-containing-protein	unknown	unknown	gnl|CDD|378689
NZ_CP017476.1|WP_096349060.1|2449663_2450116_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066089593.1|2438397_2439780_+|heavy-metal-sensor-histidine-kinase	unknown	unknown	gnl|CDD|273593
NZ_CP017476.1|WP_066089590.1|2436903_2437335_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133410
NZ_CP017476.1|WP_066089622.1|2450738_2451878_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|100107
NZ_CP017476.1|WP_066089584.1|2436000_2436186_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066089625.1|2452148_2452340_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066089608.1|2445208_2446966_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066090819.1|2437714_2438401_+|heavy-metal-response-regulator-transcription-factor	unknown	unknown	gnl|CDD|130454
NZ_CP017476.1|WP_066089618.1|2450221_2450665_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066090825.1|2448093_2448765_+|DUF3275-family-protein	unknown	unknown	gnl|CDD|371666
NZ_CP017476.1|WP_082876875.1|2451892_2452120_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066089614.1|2449399_2449651_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066089596.1|2439993_2440305_-|BON-domain-containing-protein	unknown	unknown	gnl|CDD|335963

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017476.1|WP_066089602.1|2441443_2443294_+|copper-resistance-system-multicopper-oxidase	gnl|CDD|273649	TIGR01480, unnamed_protein_product, copper-resistance protein, CopA family. This model represents the CopA copper resistance protein family. CopA is related to laccase (benzenediol:oxygen oxidoreductase) and L-ascorbate oxidase, both copper-containing enzymes. Most members have a typical TAT (twin-arginine translocation) signal sequence with an Arg-Arg pair. Twin-arginine translocation is observed for a large number of periplasmic proteins that cross the inner membrane with metal-containing cofactors already bound. The combination of copper-binding sites and TAT translocation motif suggests a mechansism of resistance by packaging and export. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NZ_CP017476.1|WP_066089628.1|2452581_2453181_+|DNA-repair-protein-RadC	gnl|CDD|178801	PRK00024, PRK00024, DNA repair protein RadC.	7.58435e-60
NZ_CP017476.1|WP_066089599.1|2440562_2440844_-|CopK-family-periplasmic-copper-binding-protein	gnl|CDD|371581	pfam11525, CopK, Copper resistance protein K. CopK is a periplasmic dimeric protein which is strongly up-regulated in the presence of copper, leading to a high periplasmic accumulation. CopK has two different binding sites for Cu(I), each with a different affinity for the metal. Binding of the first Cu(I) ion induces a conformational change of CopK which involves dissociation of the dimeric apo-protein. Binding of a second Cu(I) further increases the plasticity of the protein. CopK has features that are common with functionally related proteins such as a structure consisting of an all-beta fold and a methionine-rich Cu(I) binding site.	2.01728e-21
NZ_CP017476.1|WP_066089605.1|2444663_2445173_+|cupredoxin-family-protein	gnl|CDD|259873	cd04211, Cupredoxin_like_2, Uncharacterized Cupredoxin-like subfamily. Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins because they have an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. Majority of family members contain multiple cupredoxin domain repeats; ceruloplasmin and coagulation factors V/VIII have six repeats; Laccase, ascorbate oxidase, and spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.	4.20278e-59
NZ_CP017476.1|WP_066089581.1|2435551_2436004_-|DUF302-domain-containing-protein	gnl|CDD|269820	cd14797, DUF302, Uncharacterized domain family DUF302. These domains are mostly found in bacterial single-domain proteins and have been shown to form homodimers; they may also bind zinc. Also characterized as COG3439.	1.51657e-49
NZ_CP017476.1|WP_066089575.1|2434929_2435175_-|DUF2933-domain-containing-protein	gnl|CDD|378689	pfam11666, DUF2933, Protein of unknown function (DUF2933). This bacterial family of proteins has no known function.	1.50866e-15
NZ_CP017476.1|WP_066089593.1|2438397_2439780_+|heavy-metal-sensor-histidine-kinase	gnl|CDD|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	9.72298e-125
NZ_CP017476.1|WP_066089590.1|2436903_2437335_+|MerR-family-transcriptional-regulator	gnl|CDD|133410	cd04783, HTH_MerR1, Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator. Helix-turn-helix (HTH) transcription regulator MerR1. MerR1 transcription regulators, such as Tn21 MerR and Tn501 MerR, mediate response to mercury exposure in eubacteria. These proteins are comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain winged HTH motifs that mediate DNA binding, while the C-terminal domains have three conserved cysteines that define a mercury binding site. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	1.21882e-52
NZ_CP017476.1|WP_066089622.1|2450738_2451878_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|100107	cd02440, AdoMet_MTases, S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).	3.65757e-05
NZ_CP017476.1|WP_066090819.1|2437714_2438401_+|heavy-metal-response-regulator-transcription-factor	gnl|CDD|130454	TIGR01387, Transcriptional_regulatory_protein_PcoR, heavy metal response regulator. Members of this family contain a response regulator receiver domain (pfam00072) and an associated transcriptional regulatory region (pfam00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system. [Regulatory functions, DNA interactions].	4.49533e-118
NZ_CP017476.1|WP_066090825.1|2448093_2448765_+|DUF3275-family-protein	gnl|CDD|371666	pfam11679, DUF3275, Protein of unknown function (DUF3275). This family of proteins with unknown function appear to be restricted to Proteobacteria.	2.57554e-51
NZ_CP017476.1|WP_066089596.1|2439993_2440305_-|BON-domain-containing-protein	gnl|CDD|335963	pfam04972, BON, BON domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.	2.33325e-06

Protein sequences

>NZ_CP017476.1|WP_066089602.1|2441443_2443294_+|copper-resistance-system-multicopper-oxidase
MKHQAINSHLLPSPKRRQFVQGLASGGVLLGMSSLPAMSWAQESKKPAGGAPVLEGTEFNLEIAESAVNFTGNPRMATTINGSIPAPTLRWREGDTVTIRVTNKLRETTSIHWHGIILPYQMDGVPGISFPGIPAGETFTYRFKVEQSGTYWYHSHSAMQELTGMYGAIIVEPANGNAIRADRDHVVLLSDWTDEDPMRVFAKLKVQGDYYNRLQPTAVDFFRDASQNGVSAAVSRRKMWNTMRMNPTDLADLSADTLTFLMNGATPAGNWTGLFRKGERVRLRFINGAGNSFYDVRIPGLKLTVVQADGVNVEPVTVDEFRFGPGETYDVLVEPTDDAHTIFAQSMDRSGYARGTLATRVGLDAPVPQPDKPQWLTMADMMGSMGGDMGGMAGMAGMSHGAQMKMGGGANGMQGMAGMNHGAMAMDHSKHAMPGGGSLAAPSTKARHASTEYGASTDMRVDMARTNLDDPGIGLRDNGRRVLTLSDLHTIGGPLDPRGAEREIELHLTGNMERYTWSFDGLEFGQSTPVKFNYGERVRVILHNDTMMTHPMHMHGMWSELETAEGEFQARRHTIPVQPAQRVSFLVTADAMGRWAWHCHLMFHMEAGMFREVLVA
>NZ_CP017476.1|WP_066089599.1|2440562_2440844_-|CopK-family-periplasmic-copper-binding-protein
MKLKNSLLILAIAAAPVFAMDAQPSNLSKTVPLKGGETLYVFKDGRMAKANQFGRPVFLKQGEILTPIDGQPIAAVGNEIAQLSGLIRRGHHN
>NZ_CP017476.1|WP_066089596.1|2439993_2440305_-|BON-domain-containing-protein
MNLFSRQMALGVLLAGSMAAGFAHAAGQDANLARLVQQRVEQPDVLETKSSAVSVQVQDGNVQLSGWLQHANDYQKVHAIVAAVPGVKTVSSTFKSWASTQHP
>NZ_CP017476.1|WP_066089593.1|2438397_2439780_+|heavy-metal-sensor-histidine-kinase
MIGRLSLTARIVVLFTLISASILLGLGWLISNSVERHFMDLDRAALQDKLHLIQEIGAESTDRTDLANRLADVLQSHKDLAARIQLGSDVIYATPDSAALAMGDGVRDESPVESLIFWTRNGLSYRALEGEMVAPGASPAPLSILVVLNTQHHARYMVIFQRTLVIYVLVATLLSGVLGWFAAHSGLRPLRRMKTQAHSVNIKNLDQRMPVESVPVEMADLAKTLNEMFQRLQIDFQRLTEFSSDLAHELRTPICNMLTETQVGLSQKRSVSQHEEILASNSEELQRLTRMVSDMLYLATTENGISLPNPEFVALENEVSALFDFYEALAEEKRIALLLTGEGGTIGDRLMIRRAISNLLSNALRHTFPNESIEVSINQTANGVTLNVINAGSDIPTNVLPRLFDRFYRADSARAHPQAEGAGLGLSITQAIMRAHGGEAAASSLGGKTLFSLRFPTATA
>NZ_CP017476.1|WP_066090819.1|2437714_2438401_+|heavy-metal-response-regulator-transcription-factor
MKILIAEDEPKTGNYLRQGLSEAGYVADLVSNGVDGLHQSMEGGYDLAILDVMLPGMDGWQIIRSLRASGCDVPVLFLTAKDHVEDRVKGLELGADDYLVKPFSFSELLARVRTILRRGRAGTEVTLLKVMDLELDLLRRRVSREGKRIDLTAKEFGLLELLMRRHGEVLPRSLIASQVWDMNFDSDTNVIEVAIRRLRAKIDDPFQHKLLQTVRGMGYVIEEPEVAV
>NZ_CP017476.1|WP_066089590.1|2436903_2437335_+|MerR-family-transcriptional-regulator
MTIKSNRSKGNDQALTIGHLAKAAHVGVETIRYYQGRGLLPVPEPIGRIRYYGPELVDRIGFIKRSQGLGFSLNEVTTLLALADGLNRRAVQSVAVARLDQIHRKLDDLSRMQRALDSLLEKCIATGQAHQCPIIDALMGTGD
>NZ_CP017476.1|WP_066089587.1|2436374_2436791_-|hypothetical-protein
MTHSSINRTKRCTVLTVLMVWMFALGVGWFAACHVQGHAADNQVATNGAFLAVGAFVPLDHGLPGDGKGAPLEDCDDGPGAIVKSSTSVDSIFVAMSPPVAPEWAVQLSAAAAEDFLPARLAPGPQVPLRTCYSRLVL
>NZ_CP017476.1|WP_066089584.1|2436000_2436186_-|hypothetical-protein
MTFALSLFAFSVVTTSALAWLSWVAATDRQSKRQPASVIAIQVPQANPQVKTSATTQKGQS
>NZ_CP017476.1|WP_066089581.1|2435551_2436004_-|DUF302-domain-containing-protein
MSTAPTTASTPTATAYGFHCEITGKGFAKTVERVTEALKSEGFGVLTEIDVQTTMKAKLGVDVRPYRILGACNPPLAHRALEAEPDIGLLLPCNVVVREEADGRLCVAFMDPVAVLQMTSNPEVAAVAHEVRERLMRVKDSLAAPSINAS
>NZ_CP017476.1|WP_066089575.1|2434929_2435175_-|DUF2933-domain-containing-protein
MTTIEHKTPTPQSRKALLSRPFKTALWMVAAVASFFLVRENWALFSNNWIYLLLLACPLMHFFHGHGGHGGHSNNSNKNEE
>NZ_CP017476.1|WP_066089605.1|2444663_2445173_+|cupredoxin-family-protein
MYKTLSTLILATVPVFAMAGGTHAAAGDANASHKGMAGMKMEADHDSAAGQAGDASKVDRTIELSMDDSMRFTPSQIPVKAGETIRFFVKNSGKVPHEMVIGSLGELKEHAAMMQKMPGMQHAEANMVTLKPGQRGGLVWKFTQAGAVDFACLIPGHMEAGMVGKVNVQ
>NZ_CP017476.1|WP_066089608.1|2445208_2446966_+|hypothetical-protein
MDLLNGACFCFSLDESALARALDSVLGQAGLAEMVRQRCPFLFAAQPVFVPAPQLQRMAQVMQAVESVVALPAFREQVLAAAPQIARLGTSGPLGVFFGYDFHLSHGQLALIEVNTNAGGAMLNAVLARAQRACCTEVQGMVPSLASVVAFEQQIVDMFRHEWQLAQQAGAADKTAGVHVRHPLRSIAIVDLAPEDQYLYPEFLLFQRLFERHGLRTVIADPATLEWRDGVLWHGELAIDLVYNRLTDFYLEQPSSAALREAYLQQAVVLTPHPQVHALYADKRHLALFSDAAQLQALEVPQATQDILLAHVPRTEVVDAADAQRFWDARRSLFFKPVAGFGSRAAYRGDKLTKRVWQDILAGDYVAQAIVAPGERVIDSADVTVADVAAEASVATKAMKYDLRAYTYNGAVQWMAARLYKGQTTNFRTPGGGFAPVYSSVDVSGASGPSCASGDDDGVTPHASFVFLLDPMSGVHPVPHTLYVALARGEATLEAMAGQTLRLADWFVRLKCGAPDLVVNETYSLVCFDAQGRVDPAHAPSSAQPPAATPENPAWPTLAEREQMQQMLFGTTPSPNASDAATAAN
>NZ_CP017476.1|WP_066090825.1|2448093_2448765_+|DUF3275-family-protein
MIKCKGTLRIKKIRQSRNGAFCIADLSTDFGEFKVKDPLLDQFEEGEYQGTLWIHEIYLSQYISYGKAVTELRARLHDLQIDSEDRKQVRKPEQSEPDPIDEVPTPQVPSKPKAAWPNPAKRSDWASVKGNKLGSSMAGTPDKPVEGGPETTTPPEKVRAAVNEANVATEMFSHELAELIDQHQIVKLDPTVDRVLLRAQTAALRGKGYSFDAKQQAWIYQVT
>NZ_CP017476.1|WP_066089614.1|2449399_2449651_-|hypothetical-protein
MKKNATLVFMKEKPQLTLIEGGQPSFEAEVARLVEKPDGVAAWAKLKRLARKSRPAANSLLADVSANCQEAPPSEPDQPNIHG
>NZ_CP017476.1|WP_096349060.1|2449663_2450116_+|hypothetical-protein
MNTIVRQPLLKITVDVPAEKSDQFHLLWEQILSDEDAPINQQTRAVQSVRENAMAAGEAALHRLYGLAQGDTGQARVIARFLAGLYNGTRFPFDLTDLRTLDDALFENCMALLRMDARHCVQEVHRYFENGGVKWEQMISDWNMEKKSTS
>NZ_CP017476.1|WP_066089618.1|2450221_2450665_+|hypothetical-protein
MAITTQAFDREILVLHDEVHQVLTGVVKVKGGDVAAKIEDMKALTTQEWQSAARALLLARKTSVLEALSQQGLEAVAIGHVDVRRSLSRAIGLADEHAAMRTVQEIACRRLHLPIEEAESAMHSLETGLVHDALMEAYVSGANSRSA
>NZ_CP017476.1|WP_066089622.1|2450738_2451878_+|class-I-SAM-dependent-methyltransferase
MALMFSRLANNYVKAGYFPTDEDTLSRIQCAIAPTSSSGLIRVCDPCCGTGAALADMAQFLADYQQSAERPSKVETLGVEFDKERAWEAKKLLNRVIHADIHDVVIKPRSLSMLFLNPPYGFGVSDSANMGRDVTDGGDKAERLERTFLKKTVPTLMPGGVLVYVVPFYALDDEIRTYLARHFKDLRFYMAPEKQFQQCVIFGVKVKPGHPRKDVLDMLTMAQAGELKDQVLPLEWDESPYFLPVATDDDFDFRAVRIDGDQLQDELKRYEHNLLWPGFDRHFNQARASHRRSLRELSRWHLALALAAGQVRGMIRSKGGRSFLIKGDTFKRKQRTVSMETDEKGNVHQTVTMLDKFVPVISAIEFTPGPDKGRIVKIS
>NZ_CP017476.1|WP_082876875.1|2451892_2452120_+|hypothetical-protein
MNMQVDLTPSWGEVGTVVRRLAMSGEYVALRKIWPEAAKAFAAAQALQEVLPSLTDNQKLLVNKAMALEMSKQRC
>NZ_CP017476.1|WP_066089625.1|2452148_2452340_+|hypothetical-protein
MKTWNVHCEGRFLGTVDEDTETLARSAALSKYALTADEADAQDEQEQPVFGIAPDWEFSVTPA
>NZ_CP017476.1|WP_066089628.1|2452581_2453181_+|DNA-repair-protein-RadC
MASVIELKELQRLPDRDLLQHVLGEGVLERITSLAQAFGLQLGDEANAADVGGNYRLLCARELLCRAMHESMQGRQAFNNPSAVQEFLRLKIGGLSYETFWVLFLDSQVRLIKAEEMFRGTLTQTSVYPREIIKRALQLNAGAVIFGHNHPSGNCQPSRADENLTSTLKAGLALVDIRVLDHIIVGDASNASMAAMGLV

Crispr_ID: NZ_CP017476_5

• CRISPR_ID: NZ_CP017476_5
• CRISPR_location: 3013206-3013313
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3

Consensus repeat of NZ_CP017476_5

Consensus_repeat	Method
TGCCCCCTCGCTCCGCCGCTGCGCGG	CRISPRCasFinder

spacers of NZ_CP017476_5

>5.1|3013232|56|NZ_CP017476|CRISPRCasFinder
GTCGCTGCCCCCCAAGGGGGCTGATTCTCCTTGGGGCGGCCCTGCGGTGAATCCGG

CRISPR arrays and Neighbor proteins around NZ_CP017476_5

CRISPR arrays

The CRISPR arrays of NZ_CP017476_5

>merge|NZ_CP017476|5|3013206-3013313|CRISPRCasFinder
TGCCCCCTCGCTCCGCCGCTGCGCGGGTCGCTGCCCCCCAAGGGGGCTGATTCTCCTTGGGGCGGCCCTGCGGTGAATCCGGTGCCCCCACGCTCCGCCGCTGCGCGG

>NZ_CP017476|5|4|3013206-3013313|CRISPRCasFinder
TGCCCCCTCGCTCCGCCGCTGCGCGG	GTCGCTGCCCCCCAAGGGGGCTGATTCTCCTTGGGGCGGCCCTGCGGTGAATCCGG
TGCCCCCACGCTCCGCCGCTGCGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017476.1|WP_066084773.1|3011297_3012008_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379235
NZ_CP017476.1|WP_066084787.1|3008467_3009322_+|3-deoxy-8-phosphooctulonate-synthase	unknown	unknown	gnl|CDD|235363
NZ_CP017476.1|WP_066084752.1|3024584_3025979_+|ATP-dependent-RNA-helicase-DbpA	cas3	cd09639_cas3_CAS-I	gnl|CDD|236977
NZ_CP017476.1|WP_066084781.1|3009655_3010939_+|phosphopyruvate-hydratase	unknown	unknown	gnl|CDD|234617
NZ_CP017476.1|WP_157559326.1|3018084_3019125_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066084794.1|3006013_3006550_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP017476.1|WP_066084784.1|3009318_3009606_+|DUF1330-domain-containing-protein	unknown	unknown	gnl|CDD|377765
NZ_CP017476.1|WP_066084801.1|3002781_3003465_+|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|226629
NZ_CP017476.1|WP_066084756.1|3020516_3022448_-|TRAP-transporter-fused-permease-subunit	unknown	unknown	gnl|CDD|273983
NZ_CP017476.1|WP_066084798.1|3004645_3005899_-|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	unknown	unknown	gnl|CDD|235513
NZ_CP017476.1|WP_066085030.1|3017137_3018010_+|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|377292
NZ_CP017476.1|WP_066084767.1|3015500_3016481_-|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl|CDD|376546
NZ_CP017476.1|WP_082876687.1|3003431_3004577_+|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|131197
NZ_CP017476.1|WP_082876685.1|3023524_3024535_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP017476.1|WP_066084778.1|3011013_3011298_+|septation-ring-formation-regulator-EzrA	unknown	unknown	gnl|CDD|179156
NZ_CP017476.1|WP_082876686.1|3013378_3015373_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NZ_CP017476.1|WP_066085026.1|3022520_3023423_-|TAXI-family-TRAP-transporter-solute-binding-subunit	unknown	unknown	gnl|CDD|270238
NZ_CP017476.1|WP_066084790.1|3006784_3008452_+|CTP-synthase	unknown	unknown	gnl|CDD|235437
NZ_CP017476.1|WP_066084764.1|3016519_3017044_-|gamma-carbonic-anhydrase-family-protein	unknown	unknown	gnl|CDD|100051
NZ_CP017476.1|WP_066084759.1|3019181_3020486_-|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl|CDD|293763

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP017476.1|WP_066084752.1|3024584_3025979_+|ATP-dependent-RNA-helicase-DbpA	cas3	cd09639_cas3_CAS-I	7.8e-11	36.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017476.1|WP_066084773.1|3011297_3012008_+|ATP-binding-protein	gnl|CDD|379235	pfam13521, AAA_28, AAA domain.	8.8744e-20
NZ_CP017476.1|WP_066084787.1|3008467_3009322_+|3-deoxy-8-phosphooctulonate-synthase	gnl|CDD|235363	PRK05198, PRK05198, 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional.	0
NZ_CP017476.1|WP_066084752.1|3024584_3025979_+|ATP-dependent-RNA-helicase-DbpA	gnl|CDD|236977	PRK11776, PRK11776, ATP-dependent RNA helicase DbpA; Provisional.	0
NZ_CP017476.1|WP_066084781.1|3009655_3010939_+|phosphopyruvate-hydratase	gnl|CDD|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP017476.1|WP_066084759.1|3019181_3020486_-|sulfatase-like-hydrolase/transferase	gnl|CDD|293763	cd16144, ARS_like, uncharacterized arylsulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	2.56451e-115
NZ_CP017476.1|WP_066084784.1|3009318_3009606_+|DUF1330-domain-containing-protein	gnl|CDD|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	3.7143e-40
NZ_CP017476.1|WP_066084801.1|3002781_3003465_+|molybdate-ABC-transporter-permease-subunit	gnl|CDD|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	3.16927e-79
NZ_CP017476.1|WP_066084798.1|3004645_3005899_-|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	gnl|CDD|235513	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated.	0
NZ_CP017476.1|WP_066085030.1|3017137_3018010_+|ferritin-like-domain-containing-protein	gnl|CDD|377292	pfam04305, DUF455, Protein of unknown function (DUF455).	4.356e-123
NZ_CP017476.1|WP_066084767.1|3015500_3016481_-|Hsp33-family-molecular-chaperone-HslO	gnl|CDD|376546	pfam01430, HSP33, Hsp33 protein. Hsp33 is a molecular chaperone, distinguished from all other known chaperones by its mode of functional regulation. Its activity is redox regulated. Hsp33 is a cytoplasmically localized protein with highly reactive cysteines that respond quickly to changes in the redox environment. Oxidising conditions like H2O2 cause disulfide bonds to form in Hsp33, a process that leads to the activation of its chaperone function.	2.46547e-95
NZ_CP017476.1|WP_082876687.1|3003431_3004577_+|molybdenum-ABC-transporter-ATP-binding-protein	gnl|CDD|131197	TIGR02142, Molybdenum_import_ATP-binding_protein_ModC, molybdenum ABC transporter, ATP-binding protein. This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions].	2.29723e-129
NZ_CP017476.1|WP_082876685.1|3023524_3024535_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	6.63357e-28
NZ_CP017476.1|WP_066084778.1|3011013_3011298_+|septation-ring-formation-regulator-EzrA	gnl|CDD|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.62079e-23
NZ_CP017476.1|WP_082876686.1|3013378_3015373_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	5.86747e-49
NZ_CP017476.1|WP_066085026.1|3022520_3023423_-|TAXI-family-TRAP-transporter-solute-binding-subunit	gnl|CDD|270238	cd13520, PBP2_TAXI_TRAP, Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold. This group includes Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family and closely related proteins. TRAP transporters are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an SBP (substrate-binding protein) of the DctP or TAXI families and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function. The substrate-binding domain of TAXI proteins belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and tworeceptor cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.47424e-38
NZ_CP017476.1|WP_066084790.1|3006784_3008452_+|CTP-synthase	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP017476.1|WP_066084764.1|3016519_3017044_-|gamma-carbonic-anhydrase-family-protein	gnl|CDD|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	1.95452e-85
NZ_CP017476.1|WP_066084756.1|3020516_3022448_-|TRAP-transporter-fused-permease-subunit	gnl|CDD|273983	TIGR02123, conserved_inner_membrane_protein, TRAP transporter, 4TM/12TM fusion protein. In some species, the 12-transmembrane spanning and 4-transmembrane spanning components of tripartite ATP-independent periplasmic (TRAP)-type transporters are fused. This model describes such transporters, found in the Archaea and in Bacteria. [Transport and binding proteins, Unknown substrate].	5.22796e-115

Protein sequences

>NZ_CP017476.1|WP_066084773.1|3011297_3012008_+|ATP-binding-protein
MSLVRPAPAPIVCLLGGESSGKTTLSRALHQCLTSTHGLRVALVPEHLRTWCEARQRAPQAQEQAGIAHEQTRLIHDAQAAPGVQLVIADTSALSVAAYSALYFADESLFAPALHAQRGFAATLLMGLDIPWEADGLFRDGPALRAKADTVVREQLEGRSIPYQTIYGRREQRLGNALRALTPVLSSLLGHAPVTTDDWRTLGRPGWVCEACSDPDCEHRLFTGLLKNTGIASETP
>NZ_CP017476.1|WP_066084778.1|3011013_3011298_+|septation-ring-formation-regulator-EzrA
MASRFVPGFLIALLVVVQAQLWFGRGSLPQVNHMRKELAQLEVANREAQQRNSQIANEVRDLQEGLEMVEELARQDLGMVKPNEIFVQIAHTRQ
>NZ_CP017476.1|WP_066084781.1|3009655_3010939_+|phosphopyruvate-hydratase
MSAIVDIVGREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGSREAIELRDGDKSRYLGKGVLKAVEHINTEIGEAVLGLDASEQAFLDKTLIDLDGTDNKGRLGANAMLAVSMAVARAAAEEAGLPLYRYFGGMRAVQMPVPMMNVINGGEHANNNLDLQELMIIPVGAPSFREALRYGAEVFHALKKILHDRGISTAVGDEGGFAPNVANHEAAIQMILEAIDKAGFVAGEQIALGLDCAASEFFKNGKYELAGEGLSLNAQEWTDMMANWCDKYPIISIEDGMAEGDWDGWKLLTDRLGKKVQIVGDDLFVTNTRILKEGIDKGIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTISDIAVGTNAGQIKTGSLSRSDRMAKYNQLLRIEEDLGDVAEYPGRAAFYNLK
>NZ_CP017476.1|WP_066084784.1|3009318_3009606_+|DUF1330-domain-containing-protein
MSAYIIANVSVTNPEQYEAYKKWSSAAMQAHGAEVCVRGGAAEVLEGDWSPERIVVLKFPSMHAAKAFNASPEYSKARDARQGAAIMRMIVVEGV
>NZ_CP017476.1|WP_066084787.1|3008467_3009322_+|3-deoxy-8-phosphooctulonate-synthase
MQLCGFPIGLDRPFFLIAGPCVIESEQLQMDVAGQLKEITSSLGIPFIFKSSFDKANRSSGTTFRGPGREKGLEILAKVKRELGVPVLTDVHTEEDIIAAAAVVDVLQTPAFLCRQTDFIRAVAQSGKPVNIKKGQFLAPHDMKNVIDKARAAAKEAGLEEDNFMACERGASFGYNNLVSDMRSLAIMRESNAPVVFDATHSVQLPGGQGTSSGGQREMVPVLSRAAVAVGVAGLFMETHPDPSKALSDGPNAVPLKHMKALLETLVALDVVTKKNPFMENNFS
>NZ_CP017476.1|WP_066084790.1|3006784_3008452_+|CTP-synthase
MTKFVFVTGGVVSSLGKGIAAASLAALLESRGLKVTLIKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFIETRMKKSNNFTTGKIYQSVLDKERRGDYLGKTVQVIPHVTNEIQDYIKRGAGVGTPEAVDVAIVEIGGTVGDIESLPFLEAVRQLSLRLGPNNSAFLHLSYLPWLAAAGELKTKPTQHTAKELRAIGIQADALLCRADRPVPDEERAKISLFSNVPEWGVISMWDVDTIYKVPRMLHEQGLDGLICDKLRLNTPPANLKRWDDLVHEVEHPQHTVSVAMVGKYVDLSDSYKSLNEALRHAGMKNHAKVQIEYIDSETIDAANVAKKLGRFDAILVPGGFGARGVEGKICAAQYARENKVAYLGICLGMQVATIEYARHVAGLKDANSTEFDPKTPHPVIALIDEWQDADGSIQKRDANSNLGGTMRLGAQSSDVSDGTIAHQIYGAVVTERHRHRYEANEHYLDRLREAGLVISALTQREHLTEMVELPQAVHPWYVGVQFHPEFKSTPWDGHPLFNAYIRAALDLKGTQTLKAVA
>NZ_CP017476.1|WP_066084794.1|3006013_3006550_+|hypothetical-protein
MTHTRAFPTLATTLLIAALTACGGGSDDDIKVVPTGGALANVWFADSDGYHPLDKLKADGTFYTGSEADFGTVNPAFATDGKQQSRWAIDTSASVEGDYKVQYAMKLTSINASGTSVGKLQGNLRFDSTTGLITQFCSGFPNCYENASGSEEDFLVTVSAKVEGAKSALERSFVIRIR
>NZ_CP017476.1|WP_066084798.1|3004645_3005899_-|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC
MNDLNGKHVVLGLSGGIACYKAAELCRALVKAGATVQVVMTEAAEQFITPVTMQALSGRAVFTSQWDARSSGGADNNMPHINLSREADAILIAPASADFMAKLIHGRADDLLSLMCLARPLDKVPLILAPAMNREMWAHPATQRNVEQLRTDGATVLDVGAGDQACGETGDGRMLEPEELLYDMVRFFSPKVLEGQHVLISAGPTYEAIDPVRGLTNLSSGKMGFAIARAAHEAGAHVTLVAGPVSLPTPRGVGRINVRSALNMQKTLNVLSQNATVFISAAAVADWRPMQAAEQKIKKDGSGQVPTLSFVENPDILAGIATGVRALNNHLFCVGFAAESEDLLAHAQAKRKRKGVPLLVGNIGPDTFGQDDNALLLVDEQGEMDLPRAPKLTLARQLVAEIARRMPAPKPITPPNS
>NZ_CP017476.1|WP_082876687.1|3003431_3004577_+|molybdenum-ABC-transporter-ATP-binding-protein
MEDRAQGSRGVSATPSDAGLQLRSHLQRPGFTLDINLSLPERGITALFGPSGCGKTTALRVIAGLEPTSSGRVAIGGDVWQDSASGLFRPVHQRAVGLVFQEASLFDHLSVEGNLKFGFRRTPNAERHQAWDHGLALLGIAHLLKRSPPELSGGERQRVAIARALAANPRVLLMDEPLAALDAQRKAEVLPWLEQLHAKLDMPVVYVTHSLDEVAQLADHLVLINQGRLEAQGPVIDLLSRTDLHLAHGDQAAALIEATVAKKPPGEGLCALDFSGGQLWLPQTRAIPLPPGRSVRLRIQARDVSLALQRPEQTSLLNTLSATVSELHEDGPGQVLVGLRLGEGANQVRLLSRISQLSAQRLKLAVGTPVFALIKGVAMVR
>NZ_CP017476.1|WP_066084801.1|3002781_3003465_+|molybdate-ABC-transporter-permease-subunit
MGLTASDLQAIGLTLQVAALTTAILLLLGVPLAWWLARTQSFWRKPVGALVALPLVLPPTVIGFYLLVLMGPQGWVGQWTQALGLGTLPFSFGGLVVGSVIYSTPFMVQPVLNAMQAMGSRPLEVAATLRASPTDRFFNVVLPLCKPGLITGAVMSFAHTVGEFGVVLMVGGNIPGVTRMASVQIYDHVEALEYADAHRLAAVMLGFSFMVLLGLQIWKTEPKGAAA
>NZ_CP017476.1|WP_082876686.1|3013378_3015373_-|TonB-dependent-receptor
MHPSVHPSKKPGPARVAAGLLLCAGLSAAFPAAAATDVITLSLEELLNLTVVGASKYAQKQNEVAAAVSVVTRDEIRAFGWRTLDQALATLPGVYTTYDRQSSHLGTRGFSVPGDLNTRLLVTINGNRVNDLVFDTGPTGRDFPLDLALVERIEFIPGPGSAVYGQNAMFGVVNVVTRNGAAMDEGELALGSQPSQGMNEGRVSWGKRLDSGLDVLISASGLRSRGEDRDMEFGSTGISGRAQGLDGERDKEFFGRLGYGPWTLELVHGDRRKDDPTGVYGSDPLVAGQYQGNLYTLAQAQFESPFSDETLQVMGRVFVGQNRYSSRLSYGTPFDFPSVGDWYGGELRLLSTALDGHKLMLGMDLQDITRLNQAVIDPADSANNLLIRSPARRVGIYGQDEWHLADDLTATLGLRMDRNSTTGTHISPRAALIWQAAPSTTLKALAGRAHRAPNANERDYYDDLVLVANPSLDVESVDTLELVANHRVSEDLRLQAAAYRWTMLDQIVPGVDPVSGLSQFQPGGKVVANGLELSADKTWVWGGRLRGSLTLQDARMATGDRLANSPQQLAKFNFSMPWRAAGVSLGYEFQYDSRRKTLDGSWLGGRSLSNLHIRTDRWVDGLELGLTVRNLFNKRFAVPGGTSNWQNALEQDGRSVQFEASYRF
>NZ_CP017476.1|WP_066084767.1|3015500_3016481_-|Hsp33-family-molecular-chaperone-HslO
MSELHKFIFEGKPVRGMLVRLTDAWQDILQRRAQSGGYPAAVTELLGEMTAAATLMQSNIKFNGALVMQIMGDGPVKLAVAEVQPDLSLRATATVTGEVAEDAPLSHMVNVNNQGKCAITLDPKDRKPGQQPYQGVVPLFGDKHEKLEKLSEVIEHYMLQSEQLDTKLVLAANDKVAAGLLIQRLPLQGSANLAGEGSTAGDEDRIGLSEDYNRISILASSLKREELLELDAETILHRLFWEEDVRRFEPQTGDLGPRFACSCSRERVGGMLRSLGSDEVESIIAEQGQVEVTCEFCGAVQRFDPVDAAQVFLDAERQQPAPPDVH
>NZ_CP017476.1|WP_066084764.1|3016519_3017044_-|gamma-carbonic-anhydrase-family-protein
MALYELDGLSPQLADTAWVAENAQVIGNVTLAADTSIWFGVTVRGDTETITIGQGSNIQDGSVLHADVGMPLVVGENVTVGHKVMLHGCTIGDESLIGIGAIVLNGAKIGKNCLVGAGALVTEGKEFPDGSMIIGSPAKAMRQLTPEQMEGLRMSAKHYVDNAQRFRHTLKKID
>NZ_CP017476.1|WP_066085030.1|3017137_3018010_+|ferritin-like-domain-containing-protein
MAPETPNPSAWPGSARAWALQALCLQAPESKVASTHALYVASQSSLGAQGQIDPAEPLQAPVGDALPGRPLRPALIPPMQVPHRSPFTPEGLAALLHAICHIELNAINLALDAVWRFPDMPEDFYRDWLRVADEEASHFTLLHELLQTLGYHYGDFPAHDGLWEMCVKTQNDITARMALVPRTLEARGLDATPLIQSRLKKVNTPAALRAVAVLDVILRDEIGHVAVGNRWYGWLCARQGLEPVAHYRALARLHNAPRLKPPYNLDARRAAGFTAKELDELQAGAPNPAR
>NZ_CP017476.1|WP_157559326.1|3018084_3019125_+|hypothetical-protein
MKRLLLGTVLAACTTWAAAAPPSIDIPEWTPCAHEGQTCYTPGPAQVRFGGGGRHSEPKNTVGNIECSIANFGDPARRVPKVCEYKLGWARGMPHPVREADTGGWIDCANEGEVCRFRGTRLVRFGADGAYYYRREEREIRCTVDEFGDPVRRVPKQCQFKRSDQDRDGNGGRDREDSRQDERRDNRAAVSESRDQQRPDHPANRWAPCASEGETCRVSEPTTVRFGLDNAFNYRQVEKDAFCTSYLFGDPVPGMKKRCEANTVPIDRIVARRPAPNEIPPMDDRLWDDCGREGQLCDFRGSKHVRFGANGVFKVDFATNGVRCAEVNFGGDPARGQAKRCSIYRP
>NZ_CP017476.1|WP_066084759.1|3019181_3020486_-|sulfatase-like-hydrolase/transferase
MSTNFIFIVADDLGYADLGCYGGRAPVSPNLDALAARGARFVNGYSNSPVCSPTRFALMTGRYQYWVRGASEEPMAGRARGNPELGLFPHLPTLPSLLKEKGYHTALIGKWHLGYRPHFGPEKSGYMHHFGPMSGGVSYYGHNARGEGSDMELDGEPYDEPGYLTDLFSKRAVKYVKDRAADQQPFMLSLHYTAPHWPWETRAQGKIDPEIVKDISHLDGGNVETYQTMIREMDEGIGWVVEALRETGQLDNTFIVFTSDNGGERFSDNWPLVGGKMDLTEGGIRVPYIVHWPQGMAEKGFASEQHCMTMDWTATILDIAGASLPAGHALDGVSMLPTLQNPGHTFERPMHWRMKHNDQRALRLGEWKYLKVNEHEYLFNIERDARERANQAKRDPERLRAMRSAYEAWAAQVPAVPEDAMVSLIYTLADMPSR
>NZ_CP017476.1|WP_066084756.1|3020516_3022448_-|TRAP-transporter-fused-permease-subunit
MSWNFLDARARAGLTSVLALAVTLYGLANVMPSIGSFRLGPFPMVFFRSTFFALCFLVVVLGLKGAGGRQLPKWVDAVAWLSVVAMLYACKAFYDVSIAIDEAMFLFGPKDMWTALAACAGALFLCWRLWGAPVALLGVLGIVYMATGPYWPGPLQTIGGDVNELLAQNLWFSLDSGILGSTFSIVVTTVFPFIVLGAVLEGAGAGESMIRIAFALMKRTAGGPAHAAVLASGLFGTVSGSAVANVVGTGVITIPMIKKRGFSANFAGAVEAAASTGGQIMPPIMGAAALVMADYVGVSYLTVVIAVLVPAIAYYGSLFMMILFESRRLGIKADASSAGVAPPERQDYLNMLLVFGPLVMIVVLLVGGMSASGASIAAIALLFPMSFINPAVRRSPMKLVTALRNGGETFAQLLTAIAAVSIVISTLSATGVPVKFGVLMVSALEHSLFVALLVVAGGCILLGMGMPTLPAYVTVAAIALPSMQALGLEPLTAHMFVFMIAVASTITPPVAIAAYAAASISGGRPIGTAVQASRIGIMIFIIPFAFVYNPLILTVPQAGAAFAWGPYLLLLVKLAVAIYVMASALIRFDKRALGWPEVVARLAASVLLFAPGGHTDMVGAALTAALLGLHHWKNRTAAAVPSA
>NZ_CP017476.1|WP_066085026.1|3022520_3023423_-|TAXI-family-TRAP-transporter-solute-binding-subunit
MEAATTNSVVGLMPQTMAPHWAKVGVDVELALDQTLTKSLLKIAQGSLDSAVVPPPAYDNLLKGEGPYKALGSKGAEMAGNVRSLFGFAASIYHPVVWADGGVANWSQLKGKRVFVGPPAGAANAQIRSLIKTASGLEDGKDYEGIKAPWGAATQGFKDGQFDVFITPVGMGAQALVELGLTRKFRLLSMDQSAVPPKTLGMVRAKIPAGTYPGQVNQEDVYGWQTVMVMMASKSMSDDTAYKLTKAYFDQIPGMQKGNAQLKDLSADQRFDGMLAPLHPGAARFYKEQGIAIPDDLVAK
>NZ_CP017476.1|WP_082876685.1|3023524_3024535_+|LysR-family-transcriptional-regulator
MGNGIGTLPMPRRIGPLQSKVKFVFKHSNRHFCMDPKHLMQLAVILDKGSITEAAQHLRLTQPTLTRNMHTLEMQAGGLLFSRSRFGVKPSLLGESLAREGRAVTQTLRSATDAIGRHKMGLNNQLRVGVGPLIGMGLAAKLSGKLIAQLPQLAITVTTGRPQTVVEQLIDGQIDIAIAPAVYAQSPVGIARVLLAEDAIGVYCGPGHPLAGVSDVDSAALNAFDWINVGTSSPFQNEQLELLAKNGVRQLRTRFATLNDAVILLEFLSQGSHLAVLPGLPLLLMQDRYRFVEVPLPQGNSRRDMYIWCREELIESDVIQTFITTGRSLIENHRKA
>NZ_CP017476.1|WP_066084752.1|3024584_3025979_+|ATP-dependent-RNA-helicase-DbpA
MTTAPQTDFSALPLTPATLANLTQLGYTAMTPIQAACLPSALLGKDIIAQAKTGSGKTAAFALALLANLNPRRFAVQTMVLCPTRELADQVTTEIRRLARAEDNIKVVTLCGGVPLRGQFATLEHGAHIVVGTPGRLMDHLERGSLKLDALNTLVLDEADRMLDMGFFEDIVKVAKQCPKERQTLLFSATYPEGIAKLSAQFMKEPITIKVEAQHSDSQIEQRWYEVKSNERLHAVGLLLAHFRPASTIAFCNTKAQCRDLVEVLRGQGFSALALFGELEQRERDQVLVRFANRSCSVLVATDVAARGLDIANLEAVINVDVTPDSEVHVHRIGRTGRAGESGLALNLASMNEMGYVGKIEQLQGRESDWHPVSELTPASKEPLVPAMTTVHIQGGRKEKIRPGDVLGALTADLGYTREQVGKINVNEWSTYVAVDRNIAQQVASRLNDGKIKGKSVKVRVLED

Crispr_ID: NZ_CP017476_6

• CRISPR_ID: NZ_CP017476_6
• CRISPR_location: 3748140-3748272
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP017476_6

Consensus_repeat	Method
CACCCATGGATCTGGCTTTGCCAGGCCACAGGGTGCG	CRISPRCasFinder

spacers of NZ_CP017476_6

>6.1|3748177|59|NZ_CP017476|CRISPRCasFinder
CCCTCCCTCCCGAAGGAGAGGGGGGGTGACGCGAAGCGGCGCGGGGAGGTGCTCCGGTC

CRISPR arrays and Neighbor proteins around NZ_CP017476_6

CRISPR arrays

The CRISPR arrays of NZ_CP017476_6

>merge|NZ_CP017476|6|3748140-3748272|CRISPRCasFinder
CACCCATGGATCTGGCTTTGCCAGGCCACAGGGTGCGCCCTCCCTCCCGAAGGAGAGGGGGGGTGACGCGAAGCGGCGCGGGGAGGTGCTCCGGTCCACCCATGGATCTGGCTTTGCCAGGCCACTGGGTGCG

>NZ_CP017476|6|5|3748140-3748272|CRISPRCasFinder
CACCCATGGATCTGGCTTTGCCAGGCCACAGGGTGCG	CCCTCCCTCCCGAAGGAGAGGGGGGGTGACGCGAAGCGGCGCGGGGAGGTGCTCCGGTC
CACCCATGGATCTGGCTTTGCCAGGCCACTGGGTGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017476.1|WP_066085956.1|3739470_3740562_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl|CDD|236585
NZ_CP017476.1|WP_066085958.1|3738032_3739316_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380552
NZ_CP017476.1|WP_066085946.1|3743342_3744302_-|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|223425
NZ_CP017476.1|WP_066086386.1|3755286_3756975_-|nitrite-reductase	unknown	unknown	gnl|CDD|366994
NZ_CP017476.1|WP_066085943.1|3744351_3745170_-|CbbQ/NirQ/NorQ/GpvN-family-protein	unknown	unknown	gnl|CDD|336785
NZ_CP017476.1|WP_066085927.1|3749940_3751272_-|heme-d1-biosynthesis-radical-SAM-protein-NirJ	unknown	unknown	gnl|CDD|188566
NZ_CP017476.1|WP_066085916.1|3753269_3754466_-|protein-nirF	unknown	unknown	gnl|CDD|366994
NZ_CP017476.1|WP_096349033.1|3752230_3753220_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380027
NZ_CP017476.1|WP_066085913.1|3754836_3755151_-|c-type-cytochrome	unknown	unknown	gnl|CDD|227001
NZ_CP017476.1|WP_066085924.1|3751274_3751757_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380027
NZ_CP017476.1|WP_066085933.1|3747188_3747458_-|cytochrome-C-oxidase-subunit-IV-family-protein	unknown	unknown	gnl|CDD|377083
NZ_CP017476.1|WP_082876747.1|3748319_3749867_-|c-type-cytochrome	unknown	unknown	gnl|CDD|366994
NZ_CP017476.1|WP_066085937.1|3746661_3747096_-|cytochrome-c	unknown	unknown	gnl|CDD|365823
NZ_CP017476.1|WP_066085952.1|3740712_3741411_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP017476.1|WP_066086389.1|3754462_3754789_-|cytochrome-c	unknown	unknown	gnl|CDD|379187
NZ_CP017476.1|WP_066085922.1|3751746_3752244_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380027
NZ_CP017476.1|WP_066085931.1|3747482_3748052_-|cytochrome-c-oxidase	unknown	unknown	gnl|CDD|239213
NZ_CP017476.1|WP_066085910.1|3757226_3758066_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|381169
NZ_CP017476.1|WP_066085940.1|3745178_3746648_-|nitric-oxide-reductase	unknown	unknown	gnl|CDD|225795
NZ_CP017476.1|WP_066085949.1|3741507_3743343_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|226921

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP017476.1|WP_066085956.1|3739470_3740562_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl|CDD|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
NZ_CP017476.1|WP_066085958.1|3738032_3739316_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl|CDD|380552	cd06329, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs). Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.	9.27901e-158
NZ_CP017476.1|WP_066085946.1|3743342_3744302_-|4Fe-4S-binding-protein	gnl|CDD|223425	COG0348, NapH, Polyferredoxin [Energy production and conversion].	7.89712e-14
NZ_CP017476.1|WP_066086386.1|3755286_3756975_-|nitrite-reductase	gnl|CDD|366994	pfam02239, Cytochrom_D1, Cytochrome D1 heme domain. Cytochrome cd1 (nitrite reductase) catalyzes the conversion of nitrite to nitric oxide in the nitrogen cycle. This family represents the d1 heme binding domain of cytochrome cd1, in which His/Tyr side chains ligate the d1 heme iron of the active site in the oxidized state.	2.9105e-174
NZ_CP017476.1|WP_066085943.1|3744351_3745170_-|CbbQ/NirQ/NorQ/GpvN-family-protein	gnl|CDD|336785	pfam07728, AAA_5, AAA domain (dynein-related subfamily). This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.	2.41678e-42
NZ_CP017476.1|WP_066085927.1|3749940_3751272_-|heme-d1-biosynthesis-radical-SAM-protein-NirJ	gnl|CDD|188566	TIGR04051, rSAM_NirJ, heme d1 biosynthesis radical SAM protein NirJ. Heme d1 occurs in the cytochrome cd1 subunit of nitrite reductase in species such as Pseudomonas stutzeri. NirJ is a radical SAM protein involved in its bioynthesis. In a number of species, distinct genes NirJ1 and NirJ2 are found in similar genomic regions; this model describe authentic NirJ from genomes with NirJ only. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	0
NZ_CP017476.1|WP_066085916.1|3753269_3754466_-|protein-nirF	gnl|CDD|366994	pfam02239, Cytochrom_D1, Cytochrome D1 heme domain. Cytochrome cd1 (nitrite reductase) catalyzes the conversion of nitrite to nitric oxide in the nitrogen cycle. This family represents the d1 heme binding domain of cytochrome cd1, in which His/Tyr side chains ligate the d1 heme iron of the active site in the oxidized state.	4.33547e-110
NZ_CP017476.1|WP_096349033.1|3752230_3753220_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|380027	pfam17805, AsnC_trans_reg2, AsnC-like ligand binding domain. This entry contains an AsnC-like ligand binding domain.	1.64242e-29
NZ_CP017476.1|WP_066085913.1|3754836_3755151_-|c-type-cytochrome	gnl|CDD|227001	COG4654, COG4654, Cytochrome c551/c552 [Energy production and conversion].	2.57128e-18
NZ_CP017476.1|WP_066085924.1|3751274_3751757_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|380027	pfam17805, AsnC_trans_reg2, AsnC-like ligand binding domain. This entry contains an AsnC-like ligand binding domain.	1.01816e-34
NZ_CP017476.1|WP_066085933.1|3747188_3747458_-|cytochrome-C-oxidase-subunit-IV-family-protein	gnl|CDD|377083	pfam03626, COX4_pro, Prokaryotic Cytochrome C oxidase subunit IV. Cytochrome c oxidase (COX) is a multi-subunit enzyme complex that catalyzes the final step of electron transfer through the respiratory chain on the mitochondrial inner membrane. This family is composed of cytochrome c oxidase subunit 4 from prokaryotes.	1.80449e-06
NZ_CP017476.1|WP_082876747.1|3748319_3749867_-|c-type-cytochrome	gnl|CDD|366994	pfam02239, Cytochrom_D1, Cytochrome D1 heme domain. Cytochrome cd1 (nitrite reductase) catalyzes the conversion of nitrite to nitric oxide in the nitrogen cycle. This family represents the d1 heme binding domain of cytochrome cd1, in which His/Tyr side chains ligate the d1 heme iron of the active site in the oxidized state.	5.81269e-113
NZ_CP017476.1|WP_066085937.1|3746661_3747096_-|cytochrome-c	gnl|CDD|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	3.6904e-14
NZ_CP017476.1|WP_066085952.1|3740712_3741411_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.34336e-41
NZ_CP017476.1|WP_066086389.1|3754462_3754789_-|cytochrome-c	gnl|CDD|379187	pfam13442, Cytochrome_CBB3, Cytochrome C oxidase, cbb3-type, subunit III.	6.68472e-08
NZ_CP017476.1|WP_066085922.1|3751746_3752244_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|380027	pfam17805, AsnC_trans_reg2, AsnC-like ligand binding domain. This entry contains an AsnC-like ligand binding domain.	3.87515e-17
NZ_CP017476.1|WP_066085931.1|3747482_3748052_-|cytochrome-c-oxidase	gnl|CDD|239213	cd02862, NorE_like, NorE_like subfamily of heme-copper oxidase subunit III. Heme-copper oxidases include cytochrome c and ubiquinol oxidases. Alcaligenes faecalis norE is found in a gene cluster containing norCB. norCB encodes the cytochrome c and cytochrome b subunits of nitric oxide reductase (NOR). Based on this and on its similarity to subunit III of cytochrome c oxidase (CcO) and ubiquinol oxidase, NorE has been speculated to be a subunit of NOR.	3.85687e-52
NZ_CP017476.1|WP_066085910.1|3757226_3758066_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	1.1895e-121
NZ_CP017476.1|WP_066085940.1|3745178_3746648_-|nitric-oxide-reductase	gnl|CDD|225795	COG3256, NorB, Nitric oxide reductase large subunit [Inorganic ion transport and metabolism].	6.07777e-159
NZ_CP017476.1|WP_066085949.1|3741507_3743343_-|VWA-domain-containing-protein	gnl|CDD|226921	COG4548, NorD, Nitric oxide reductase activation protein [Inorganic ion transport and metabolism].	9.65468e-130

Protein sequences

>NZ_CP017476.1|WP_066085931.1|3747482_3748052_-|cytochrome-c-oxidase
MSARAEPRLVGDGVIWLLVLVELLTFGILFLSFAVARWREPGVFLQGQGALSLSTGALNTLLLVGASWCAARAVMALRAGLSAAGGWWLLGALGGAVGFLVVKSHEFAGKIASGFDWADDSFTMLYTLLTGFHFLHVLVGAVVFGVLGWHARQGAYGPQHLNAPESGAVFWHMVDLLWMVLFALVYVIR
>NZ_CP017476.1|WP_066085933.1|3747188_3747458_-|cytochrome-C-oxidase-subunit-IV-family-protein
MSFLHRNDGIALALAAATACTWWLGEGGHEAISPAVVGSVLALAGLKGYLIANEFMELRHAPAVWRRLVLGWLVLVIGSIGLVSWLASR
>NZ_CP017476.1|WP_066085937.1|3746661_3747096_-|cytochrome-c
MSQSQSGFTKQMARNMFYGGSMFFILLFAAIIFDSERRIPERSNAQNITPAVIAGKKVWETRNCIGCHTLLGEGAYFAPELGNVYKRRGGEFIKAWMKAMPTGAPHRRQMPQFNLTDEQLDNVVEFLKWTGEINTENWPPNIEG
>NZ_CP017476.1|WP_066085940.1|3745178_3746648_-|nitric-oxide-reductase
MTIKTLKYQSQSVAKNYFIAAMVLFAAQIIFGITLGLQYVIGDLFFPYIPFNVARMVHTNLLIVWLLFGFQGAAYYMVPEESETELFSTKLANLLFWVFLVAGGLTIVGYLTVPYAKLAELTGNDMLQTMGREFLEQPLPTKVGIVIVMLGFLFNISMTVLKGRKTAISMVLLIGLWGLALMFLFSFVNPHNLVRDKMYWWFVVHLWVEGTWELILGALLAYVLIKTTGVDREVIDKWLYVIIAFALMSGILGTGHHFFFIGLPGYWLWIGSIFSALEPLPFFMMTVFAFNMVQRRRREHPNQAAVLWAVGCAVMGFLGAGLWGFLHTLSAVNYYTHGSQLTAAHGHLAFYGAYVLVVITLISYAMPTLRGRIANSPRAQSYEMWSFWVMTIGMAVMVLALTGAGILQVWLQRMPTDGTAMGFMATQDQLAYFYWVRIVGGVVFLIGQFMYFASFFIGGEHVLKDNVATPVRSGGGGMLRGQPAQRARS
>NZ_CP017476.1|WP_066085943.1|3744351_3745170_-|CbbQ/NirQ/NorQ/GpvN-family-protein
MNAMDQSEQRLLAQADIPFYAEQAGESTLFEHAFRQRLPVLIKGPTGCGKTRFVEHMAARLGRPLITVSCHDDLSAADLVGRHLIGDNGTVWADGPLARAVRTGAICYLDEVVEARKDTTVVLHPLADDRRVLPIERTGEQLVAPPGFMLVISYNPGYQNLLKSLKPSTRQRFIALTFGYPDPAVEQAIIEREAGVDAALASRLVQLATALRRLTDHDLEETASTRLLVMAARLVASGLPLPVACRAAIVDALTDDAETAAALDEVVSAVVG
>NZ_CP017476.1|WP_066085946.1|3743342_3744302_-|4Fe-4S-binding-protein
MQRRRLFFQLGFFALFLLAPALDLLRFDLNEAQLWVFGQRWSLGIDAFKAGEITANQAAIQIFLRAFLPVILLVVAFLGVAYRYGRLYCGWLCPHFTLVETLNNALHRASGKLSFWDKHRTHRANVEPTARWWPVFGALCLGFGFLWAITLLTYLLPPAAIWGNLIGGTLTPNQARFLVIGTAVFTLEFAFARHLFCRFGCAVGLFQSLAWMANPKGMVVSFDRDHARDCRTCSTAVYPGGSACDNGCPMRLHPRNIKRMMFSCVQCGQCLDSCDETQSAKTREPLLEWKVGADAVRETLRQRKAEMAAEASDTAKVRL
>NZ_CP017476.1|WP_066085949.1|3741507_3743343_-|VWA-domain-containing-protein
MEEWVGAQWHRFIQKAASKQHAHAAVHLPDVQRTIGMLFRAGGGAHAVRVAPATDVRAGGPRDWLQRIAGSGTHASTGRMEPEALSLPSTVAVFDDHALNRALYLWLAAMAAVIEPTGDWVMDNVRATAAAQQRFPGLGQRYAALRAAQQALRPDASRLKGRAAQAEVLVQLALAGEPVAAGSGLLPGDVAPVWLWLDVGAGPAAAPSRGDPEKAEGATRKPSVSDARRRKAQAVSDDRDKAPLMMFFRAESVLSWGEFIKVNRATDDDPDENASNVANDMDMLAIAPDGQSAASRVKFDLDLPSAAADDRPLGPGQRFPEWDFRRNALLPDHCALQTFLARPSEAYQPPAALKATAKRVRRRLEILRAGTGRARGQSEGDDIDLDAWVRHRVDALSSPTSEAPPVFTRRVRTERSLATLLLADLSLSTDAYATQTARVIDVIRDALYVFGEALAASGDPFEMLGFSSVRRHNVRIQHLKGFNEPWNVAARDRVGAIKPGYYTRMGAAVRLATERLIARPERQRLMLILTDGKPNDLDVYEGRYGLEDTRHAVQAARAAGLIPFCITIDESAHDYLPMLFGQQGYALVHRPQDLVSRLAAVYMRFMRQSGA
>NZ_CP017476.1|WP_066085952.1|3740712_3741411_-|Crp/Fnr-family-transcriptional-regulator
MDLAQFDLPRYLSMLPLFHDMDKDELARLAEGSKLRTFARGEDVFHIGDPCNEFHVTVSGQIKLFAVSPAGQEKIIEIVGPGNSFGEALMFTNKPYIINAQALTETLLLSVSKASLLREIEGDTRFCMRMLAGLSRRLHGLINDVQAYSLHSGVERVVGYLVRDLPEVGDQADTVQRVVLPVSKAAIASRLSMTPEYFSRVLHELEAKGLIEVDKREIRIPDPQRLNRFPLS
>NZ_CP017476.1|WP_066085956.1|3739470_3740562_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MLILGFESSCDETGVALVDASGSATPRLLGHALHSQIEMHQAYGGVVPELASRDHIRRVLPLTDSVMQQAGLPLSAVDAIAYTRGPGLAGALLVGSGVACAMAMALGKPAMGVHHLEGHLLSPFLSADPPEFPFVALLVSGGHTQLMRVDGVGRYQMLGETIDDAAGEAFDKSAKLLGLGYPGGPALSRLAQQGSPTAFKFPRPLLHSGDLDFSFAGLKTAVLTQVKRLANERPEGPATPQLAAALGLAQKADVAASAQAAIVDVLVKKSMAAIASTGLTRLVVAGGVGANALLREQLNAECERRSLRVHYPELHLCTDNGAMIALAAGLRYQAGLMPTTLSEPGYRFDVSPRWPLASVCIAA
>NZ_CP017476.1|WP_066085958.1|3738032_3739316_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MIQYSIRRRLLSGLLCATGLIHMGQAQAASPAIEPVRIGMIEGLSGPFANTGEAVYRNLVWAAERVNARGGVKLPGGNRPMVIERFDSKGQTEEALAGLRSAVDQGIRVITQGNSSSAAAGLIDGIEKLNQRDPTHSVVFLNYSAVDPSLTNEKCSFWHFRFDAHADMRMTALMSVLKEDAALKRIYLIGQDYSFGQGVLREAKRQLGTTRPDVTIVGEELHPVARVKDFAPYAAKIVASGAQAVLTGNWGNDLTLLVKAAREAGFEGSFYTFYGNALGAPSAMGDAGVGKVIAVADWFPNTPTAASEAFYQSFRQRFPKPEDDYVHMRMQLMIEALAQAIERAGSMDAVRIATELEKAEVTLAGQTARMRAGDHQFQQPLAVATMDRQGAPGTRFDVEGSGYGFRVVRQLTAKQAELPHRCSMTRP
>NZ_CP017476.1|WP_082876747.1|3748319_3749867_-|c-type-cytochrome
MGVDMARAQSADQTVGAASLYTEHCAACHGAQRTGGMGPALLPESLTRLRSAEALKVIAQGRVATQMPGFADKLSKEQIAALAAFVRTPVLPAPEWADADIRASREFHPAPPNEPAKPVWDADPMNLFVVVEGGDHHVSLVDGDKFEVITRFASRYALHGGPKFTPDGRYVFFGSRDGWITKYDLWRLRVVAEVRAGFNMRNVAVSGDGKWVMAANYFPHTLALFDADLNLKQTYAAATLDGKTTSRVSAVYDAEPRQSFVVALKDIPELWEISYNPKAQPIFDGYVHDYKMGEGIAKSGFLGVRRTPLEQPLDDFFFDQSYANVLGATRGEEGSKADGASAQVVNLDARSKIAELPIAGMPHLGSGITFAWNGSTVLASPNLKDGAIDVIDMKTWKTVATIPTPGPGFFMRSHENTRFAWTDSMMSPTARDTLTIIDKSTLKTVAEVKEPGKTLAHIEFTKDGKYALASVWEMDGALVIYDATTFKEVKRLPMSKPVGKYNVWNKITRSEGTSH
>NZ_CP017476.1|WP_066085927.1|3749940_3751272_-|heme-d1-biosynthesis-radical-SAM-protein-NirJ
MFRISQYLREIAQAEKTGVYPSPIGRHVSGQGAAESALPGGRGLAAQGAGAVGIQKPGPVVIWNLIRRCNLTCKHCYALSADHEYEGELSREEVFTVMDDLKAYRVPVLILSGGEPLLRPDIFEIAQRSRDMGFYTGLSTNGTLIDEPMADRVAAMGFNYVGISLDGLRETHDKFRRLEGAFDRSLAAVHLLHERGVKVGLRFTMTAMNAHDLPALLDLMRTEQVDKFYFSHLNYAGRGNIHRGKDAQFQATRDALDMLIERAWDAAQRGLDEEYVTGNNDADGPYLLNWVEARFPQWAPMLRERLVAWGGNSSGVNVANIDNLGHVHPDTMWWHHKLGDVRERPFSAIWSDTSEPLMAGLKAKPRAVKGRCAVCKHFDICGGNTRVRAQQLTGDAWAEDPGCYFTDEEIGATAGSDATRLTMEPVSGKRRVVAIHLEENTHV
>NZ_CP017476.1|WP_066085924.1|3751274_3751757_-|Lrp/AsnC-family-transcriptional-regulator
MPLDELDRRLIRATQGGLPLLPRPYEAVGAMLGIDGEQVRRRMQAMLDAGLIRRIGAVPNHYRLGFTANGMSVWDVADDLVDELGERIGQLSGVSHCYRRPRRLPVWRYNLFAMLHGRSREEVERQAEDIAAMLGPACAAHDILYSTAILKKTGLRLNES
>NZ_CP017476.1|WP_066085922.1|3751746_3752244_-|Lrp/AsnC-family-transcriptional-regulator
MLSPDDARLVAFLHGGFPLTDRPFADVAEQLGCPEDVVIERLQRLLSHGDLSRFGPLFQIERAGGRFVLAAMAVPEPRFDAVAELLNGISEVAHNYRRESAHPDQPNATPLNMWFVLAVESADLIAPTIAHIEAVTGLSVFDFPKDREFFVELKLPLLEGLGHAT
>NZ_CP017476.1|WP_096349033.1|3752230_3753220_-|Lrp/AsnC-family-transcriptional-regulator
MALLNEWQHGFPLVREPFLQIAQALSLNEAQVIGSFQQMQERGAISRIGGVFSPGAGGAALLAAMAVPADRLDAIAAQVSAHPGVNHNYEREHRFNLWFVMTGTDAHAVNAAMDGLERETGLPALRLRMERAYRIDLGFDLRHATAQAPMRVHRGGDTAALVGKDHLLAACVEQGLSITARPFDAWASACECSPEEIIDRLQRWVDAGTLKRFGVVVRHHELGFSANAMTVFNVPEDQVDACGELLAAQPGVTLAYKRERAQGWPFNLYCMVHGTHREAVHAVIERVIPAVGLTHYPREILFSTRRFKQTGARRFRSLPNAQEPAHALA
>NZ_CP017476.1|WP_066085916.1|3753269_3754466_-|protein-nirF
MKRRHLLASAAVTLPSLAALGLLPGCAASMLRGTGDLGVVIGRANGTLYLVDTTAQALIGEVSGLGDLSHASVVFSRDGLFAYVFGRDGGLTQVNLLERRITRRVMQAGNSIGGAISADGSLVAAQNYTPGGVKIFDAHTLALVADVPAEYAPGKLSKVVGLVDLPGRRFAYSLFEGNAIWVIDCTDPARVGIQKFEGVGQQPYDALVTPDGRHYIAGLFGEDGLAMIDLWAAEPKVQRILSGYGKGQEALPVYKMPHLRGWAVAGRRAYLPAIGRHEVLVVDTDTWKEVGRIPVAGQPVFVMARPDGRQVWVNFSVPDYHRVQVIDTQTQTIVKTLEPGKAVLHMEFTPRGESVWISSRDDNRVSIIDTQTLATRARLDVPSPSGIFFTSRAARLGF
>NZ_CP017476.1|WP_066086389.1|3754462_3754789_-|cytochrome-c
MLGLAAHPTFAESPGAPQGSRVQALVHMVRQDCGSCHGMRLTGGLGPALTREALAGFPLESLAATIYHGRPGTPMPPWSAMLNEAEARWIAQQLLQGFPEETTTPHIQ
>NZ_CP017476.1|WP_066085913.1|3754836_3755151_-|c-type-cytochrome
MKTLSLIVAAVALAFSAGSAMADGEAALTKGGCMACHAKDKKLVGPSFKDIATKYKGQDVSAQLMDKVRKGGSGVWGPIPMSPNPVAKIDDDSLKEAVAFILKS
>NZ_CP017476.1|WP_066086386.1|3755286_3756975_-|nitrite-reductase
MAAMLVAGSLHAEDVKKTLTQPEANYQAGSSPIGESPMHQSVNPKAPPMTQAEFDLGRKIYFERCAGCHGVLRKGATGKPLTPDLTVGKGTDYLKVFINYGSPAGMPNWGTSGELNDQEVDLMARYIQHEPPIPPEYSLADMKSTWKVIVPPEKRPTKKMNNYNISNIFSTTLRDAGEIALIDGDSKEIISILKTGYAVHISRMSASGRYLFVIGRDAKVNMIDLWMEKPDTVAEIRTGLEARSVESSKFKGYEDKYVIAGTYWPPQFVIMDGDTLEPLKIVSTRGNVVGTQEYHPEPRVASIVGSHFKPEFVVNVKETGKTLMVDYSDLKALKMTEIGSAPFLHDGGLDSSKRYFMVAANNSNKISVIDLKTDKLAALIDVGKIPHPGRGANFIHPKFGPVWSTGHLGDETISLIGTDPVKHPKNAWKVVQTLTGQGGGALFIKSHPKSNHLYSDTPLNPDPKISQSVAVYDINNLAKGYTVLPIAEWADIKDDGAKRVVQPEFNKAGDEVWFSVWSAKDKISAMVVVDDKTLKLKAVIKDPRLITPTGHFNVNNTQNDVY
>NZ_CP017476.1|WP_066085910.1|3757226_3758066_+|uroporphyrinogen-III-C-methyltransferase
MSVMEPSHWLTPGWSENEPGFDGPPAAVTLVGAGPGDPELLTIKAMRALQAAKLVLYDHLVSPGVLDMLPPDADRVYVGKESSRHTLPQTDIIELMVRLARSGRPVLRLKGGDGYIFGRGGEEAQALAAAGVPFTVVPGLTAAQGAAASVGIPLTHRDHACSLVLSTGHMRENRVLDMDWEMLARPRQTVVLYMGVNNLPEICAQLIAHGLPENTPAALVERATQPEERCITGTLANLPDLAKEHRVKPPALIMVGAVVALRAELMPSQHAEQRLATTT

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP017476_4	4.1|2443525|23|NZ_CP017476|PILER-CR	2443525-2443547	23	NZ_CP017476.1	2443735-2443757	0	1.0
NZ_CP017476_4	4.1|2443525|23|NZ_CP017476|PILER-CR	2443525-2443547	23	NZ_CP017476.1	2481062-2481084	0	1.0
NZ_CP017476_4	4.2|2443585|25|NZ_CP017476|PILER-CR	2443585-2443609	25	NZ_CP017476.1	2443673-2443697	0	1.0
NZ_CP017476_4	4.1|2443525|23|NZ_CP017476|PILER-CR	2443525-2443547	23	NZ_CP017476.1	2443630-2443652	2	0.913

1. spacer 4.1|2443525|23|NZ_CP017476|PILER-CR matches to position: 2443735-2443757, mismatch: 0, identity: 1.0

gcacacctgctgaatctgccggt	CRISPR spacer
gcacacctgctgaatctgccggt	Protospacer
***********************

2. spacer 4.1|2443525|23|NZ_CP017476|PILER-CR matches to position: 2481062-2481084, mismatch: 0, identity: 1.0

gcacacctgctgaatctgccggt	CRISPR spacer
gcacacctgctgaatctgccggt	Protospacer
***********************

3. spacer 4.2|2443585|25|NZ_CP017476|PILER-CR matches to position: 2443673-2443697, mismatch: 0, identity: 1.0

tggtggtgcctccatgcccatggaa	CRISPR spacer
tggtggtgcctccatgcccatggaa	Protospacer
*************************

4. spacer 4.1|2443525|23|NZ_CP017476|PILER-CR matches to position: 2443630-2443652, mismatch: 2, identity: 0.913

gcacacctgctgaatctgccggt	CRISPR spacer
gcacacttgcggaatctgccggt	Protospacer
******.*** ************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017476_4	4.1|2443525|23|NZ_CP017476|PILER-CR	2443525-2443547	23	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	410732-410754	2	0.913
NZ_CP017476_4	4.1|2443525|23|NZ_CP017476|PILER-CR	2443525-2443547	23	NZ_CP041050	Citrobacter sp. CF971 plasmid pBM527-4, complete sequence	33398-33420	3	0.87
NZ_CP017476_4	4.1|2443525|23|NZ_CP017476|PILER-CR	2443525-2443547	23	NC_007901	Rhodoferax ferrireducens T118 plasmid unnamed1, complete sequence	13016-13038	3	0.87
NZ_CP017476_2	2.1|1483101|38|NZ_CP017476|CRISPRCasFinder	1483101-1483138	38	NZ_CP019241	Rhodoferax antarcticus strain DSMZ24876 plasmid unnamed1	24259-24296	6	0.842

1. spacer 4.1|2443525|23|NZ_CP017476|PILER-CR matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 2, identity: 0.913

gcacacctgctgaatctgccggt	CRISPR spacer
gcacacctgctgaagccgccggt	Protospacer
************** *.******

2. spacer 4.1|2443525|23|NZ_CP017476|PILER-CR matches to NZ_CP041050 (Citrobacter sp. CF971 plasmid pBM527-4, complete sequence) position: , mismatch: 3, identity: 0.87

gcacacctgctgaatctgccggt	CRISPR spacer
tcacacctgctgagtctgccggc	Protospacer
 ************.********.

3. spacer 4.1|2443525|23|NZ_CP017476|PILER-CR matches to NC_007901 (Rhodoferax ferrireducens T118 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

gcacacctgctgaatctgccggt	CRISPR spacer
ctacacctgctcaatctgccggt	Protospacer
 .********* ***********

4. spacer 2.1|1483101|38|NZ_CP017476|CRISPRCasFinder matches to NZ_CP019241 (Rhodoferax antarcticus strain DSMZ24876 plasmid unnamed1) position: , mismatch: 6, identity: 0.842

cagcgacccgcgcagcggcggagcgtgggggt-catggt	CRISPR spacer
cagcgacccgcggagcggcggagcgcgggggcacaaag-	Protospacer
************ ************.*****. ** .* 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	4639928 : 4648283	8	Acinetobacter_phage(50.0%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP017476|4639928:4648283|DBSCAN-SWA
ATTAAGCAATGATTTTCGCAACCACGCCAGCACCAACCGTACGACCGCCTTCGCGAATGGCGAAGCGAAGACCCTCTTCCATGGCGATGGGGTTGATCAGCTTGACGGTGATCGACACGTTATCGCCAGGCATCACCATCTCTTTGCCTTCTGGCAGCTCGATGGAACCGGTCACGTCCGTCGTGCGGAAGTAGAACTGGGGACGGTAGTTGTTGAAGAAAGGCGTGTGACGGCCACCTTCGTCTTTGGACAAGACATAGATCTCGCCCGTGAAGTGGGTGTGTGGCTTGATCGTACCGGGCTTGCACAGCACCTGGCCGCGCTGCACGTCTTCGCGCTTGGTGCCGCGAAGCAAGATACCGACGTTGTCACCAGCCTGACCCTGGTCCAGCAGCTTGCGGAACATTTCCACACCGGTGCAGGTGGTCTTCTGGGTATCGGCAATACCAACGATTTCGATTTCTTCACCAACCTTGACGATACCGCGCTCGATACGGCCGGTCACCACGGTGCCACGACCGGAGATGGAGAACACATCTTCCACAGGCATCAGGAACGCACCGTCAACAGCGCGCTCCGGCATAGGGATGTAGGTGTCCAGTGCGTCGGCCAGCTTCATGATGGCCTCTTCACCCAATGGGCCCGTGTCGCCTTCGAGGGCGAGCTTGGCGGAGCCATGAATGATCGGGGTGTCATCACCAGGGAAGTCGTACTTGGTCAGGAGCTCACGCACTTCCATTTCGACCAGTTCCAGCAATTCAGCGTCGTCCACCATGTCGGCCTTGTTCAGGAAAACGATGATGTAAGGCACGCCCACCTGGCGCGACAACAGGATGTGCTCGCGGGTCTGTGGCATTGGGCCATCAGCGGCGGAACACACCAGAATGGCGCCATCCATCTGGGCAGCACCGGTGATCATGTTTTTCACATAGTCAGCGTGGCCCGGGCAGTCAACGTGTGCGTAGTGACGATTGGCCGTCTCGTACTCAACGTGAGCGGTGTTGATGGTGATACCGCGGGCCTTCTCTTCAGGTGCAGCATCAATCTGGTCGTAGGCCTTGGCCGTGCCACCAAACTTCTTGGACAACACGGTCGCAATAGCGGCCGTCAGCGTGGTCTTGCCATGGTCAACGTGACCGATGGTGCCCACGTTGACGTGCGGCTTGGATCGTGTGAATTTTTCTTTTCCCATTTTTCAGCTCCAAAATCAAAACTGCCGAAACACCAGAACAGACATAAAAATACTGGTGCCCTTGGCGGGAATCGGACCCGCGACCTCTCCCTTACCAAGGGAGTGCTCTACCACTGAGCCACAAGGGCTAAAACACCCCAAAGGGCATTTCAACAAAACTACCTCCGCCACGCGGCGGATTCAAACTACCAGCGAACTGGAGCGGGAGACGGGAATCGAACCCGCGTGATCAGCTTGGAAGGCTGGAGTTCTACCATTGAACTACTCCCGCCCGAAACACCTTCGGCCAAGACCGAAAATCATCCAAGCGCTTTGGTTTCCCACTGCTTACAGACTCTCACTATCGCTATCGGCTGGTGGAGGGGGCTGGATTCGAACCAGCGTACGCGTAAGCGGGCAGATTTACAGTCTGCTGCCTTTAACCACTCGGCCACCCCTCCATAAGCACAGCCCAACATTATGCCAGCTTTTTGGAGGGCAAGTGCGGGTTATTCCGAACTTCACCAATGAATTTCTGTTTCGCCGGCCTCCGACAGCCACCGATTGGTCTTGGAAAAGTGTCCGCAACCGAAAAACGGTGCGGGACCGCGGCTGGCCGACAGGGGTGATGGGTGATTGGCAGACAACACGCAGTGGCGCTTGCCATCGATCAAAACAGACTTTTTCTGGGCATGCGCGCCCCAGAGCAAAAATACCTTGGGGGGACCTCGATCGCTGCAGCAACGAATCACGGTGTCGGTCAAAGACTCCCAGCCCTTCCCCGCGTGGCTGGCCGGCTGTCCGTCCTCGACTGTCAGACAGGTATTGAGAAGCAACACACCCTGCTTGGCCCATCGCACAAGGGAGCCATTGGAGGGGGGAGCCAATCCCAGATCGCGCAGCAATTCTTTGAACACATTGCGCAAGCTGGGGGGCAACCTGATCCCCGGCGCCACCGAAAACGCCAGGCCTTCGGCCTGACCTGGGCCGTGGTATGGGTCTTGGCCCAGAATCACCACGCGCACGTCTGCCGGGGCTGTGAGCGCCAAGGCCCTGAGCGGCTCAGGTGGATAGATCACCGCCCCGGCTTTCAGGCGCCCATCCAAAAAGTGCAACAGCCCCTGTCCGACTTTTTCGGCCCAAAAAGCGTCTACCGACGCCTGCCAATCTGGCGCCACCGGCCAAGCCTTGGGATCCACGGCCGTCAACCACAGTGGTGCTGCGGCAGGATCGGGCTCCTCACCCCAATGCAAAAGGCGTTGCCCAGCGCGCGCTCCGGGCATGGTCAGGCAAACAACTCGGCCAGCGCCAGCCCCGGCTCAGGCGCACGCATGAAGGCTTCACCCACCAAAAAACCGTGCACCCCTGCTTCACGCATGCGCATGACATCGTTCCGGCCCAGGATGCCTGACTCTGTGATGAGCAAGCGATCTGGGGGCACGTCGGACATCAGATCCAGTGTGGTTTGCAGGCTGACTTCAAAAGTGCGCAAGTTGCGGTTGTTGATGCCCAACAACGGCGTTTGGAGCTTCAAGGCACGGTGCAACTCGGCGCGGTCGTGCACCTCGACCAACACCGCCATGTTCAAGCCCTGCGCAATGGCTTCCAGGTCGGCCATCTGCGCATCGTCCAGGCAGGCCGCGATCAGCAGGATCGCGTCGGCACCCATGAAACGGGCTTCATAGACCTGGTAGGGGTCGACCATGAAGTCTTTGCGCAACACCGGCAGATCGCAGCTGGCCCGCGCCTGCTTCAGGTAGTCGGTGCTGCCCTGGAAAAACTGGCGGTCGGTCAACACCGACAAACAGGCCGCGCTCACCTGTCCGTCGCCTTCGGCATAGCTTTGCGCGATGTCGGCCGGGATGAAGTCACTGCGCAACACGCCCTTGCTCGGGCTGGCCTTTTTGACCTCGGCAATCACCGCCGCCTGGCTCTTGGCGATCTTGGCTCGCAGGGCGGCTTCGAAATCGCGGGTGAGCACGCGGCTTTCGGCGTCAAAACGCATGGCTTGCAGCGGTTTCTTGGCCAGCGCAGCGGCGATCTCTTCGTGCTTCACGGCCACGATCTTTTGCAGTATGTCATTCATGGGAACGGGGTTCTTCCAAAGGGGTTGTGCCCGAAGGCGGAGCGCCTGCCGGGTCTTTCAAGACATTGACCACCACCCGGTGCATCACCACCGCAGCGATCACAAACACCAGGGAAACGCCGATCGCGATCCAGGCGCCTTCGTTTTGCAGCCAGGGCGGCAACGCCATGGATCAGATCAGGCGGAGGCCGGGCTGGCAGCGGTGTGCGATTTCAGCTCGGTCAGCTTGCTGGCCGCCGCGCCCGACTCGATCGCGCTGCGCGCCAAGGCAATGCCTTCGCCCATGTCACCACACACATTGGCGGCGTACAGCGCCGCGCCCGCGTTGAGCACCACGATGTCGATCGCCGGGCGGATGGCCGGGTCGTCGCTGTTGTTCAGCACGCCCATCAACATGGCGCGCGACTCATCGGGGGTTTCCACGCGCAAGGCGCGGTTGCTGGCCATGGTGAAGCCGAAGTCTTCAGGGTGAATTTCGTATTCGGTGATCTCGCCATCCTTCAGCTCGCCGACCATGGTGGCCGCGCCCAGGGAGACCTCATCCATGCCATCGCGGCCATAAACCACCACCGCGTGTTCCGCGCCCAGGCGCTGCAGGGCGCGCACCTGGATACCCACCAGATCGGGGTGAAAGACGCCCATCAGGATGTTCGGCGCCGAGGCCGGATTGGTCAGCGGGCCCAGGATGTTGAAAATGGTCTTGATGCCCAGCTCTTTGCGCACAGGGGCAACGGCCTTCATGGCGGGGTGGTGGTTGGGCGCAAACATGAAGCCGACACCCACTTCTTCGATGCAGCGGGCAATCGCCTCCGGGGGCAGGTTGATGTTGATGCCGAGGCTTTCCAGCACATCGGCGCTGCCGCTCTTGCTCGACACGCTGCGCCCGCCGTGCTTGCTCACCTTGGCACCCGCGGCGGCGGCAACGAACATGGAACAGGTGGAAATGTTGAATGTGTGCGAGCCATCACCACCAGTGCCCACGATGTCAACAAGATGCGTCTTGTCAGGCACATTGACCTTCGTTGAAAACTCTCGCATCACCTGCGCAGCGGCGGTGATCTCGCCAATGGTCTCCTTCTTCACCCGAAGGCCGGTGATCAAGGCGGCCATCATCACTGGCGACATCTCGCCGCTCATGATCATGCGCATCAGATGCAGCATCTCGTCATGAAAGATCTCGCGGTGTTCGATCGTGCGCTGCAGCGCTTCTTGGGGGGTGATTTTTTGGGCGTTGGGCATCGTCATCTCCAGAATCTCTAAGCAGAGGGATTGTCGGACATGGCCAGTTTCAAGCCAAACCCGACGAACATCAGGCCCGCCACGCGGTCCATCCAGCGCATGGCGCGCTGGACGGTCTGCAAGCGCTGCGCGGCCCTTGCGGCCAGCCATGCGTAAGCAAAATTGACCGGCAGGGAATTGATGTTGAACAGCAATCCAAGCAACAAAAATGCCGCGACCTTGTTGGGCGCATCGTGCGCGATGAACTGCGGGACAAAGGCCAGGAAAAACAGCGCCACCTTGGGGTTGAGCACATTGGTGAGGAATCCGCGCTGATAGAGGGTGACGAGACTGACCGGCTGAGGCGATTGGGTCGGGGCCGGCGTCATGCCAGACGAAACGCCCTGGCTTGCCATCAGCAGTTTCACACCCATCCAGACCAGATACGCGGCGCCGCCCCATTTGAGCACCGTGAACGCCGTGGCCGACGTGGCAAGCAGCGCGCCCACCCCGAAGGCTGCCGCGAACACGTGCACGAAACAACCGCTCACGATGCCCAGTGCCGCCACGACGCCTGCACGCACTCCGCCTTTGAGCGCCGTGTTCACGATATAGAGCACATCGGGCCCCGGCGTGAGGTTGAGCAACCAGCCCGCGGCAATGAAGACCAGTAGGTGGGCGGTATCGGGCATGACCACACCCAGGCTCAGTAAACCGCGGAACCCGCGGCCGCACCAGCTGGAGGGACAGCGGGCAGCTCGGCAAAGAAGCGCCGAATGGTGGTCAGCGCATGGTCGATACCCGCGGCGTCCACATCCAGGTGGGTCACAAACCGCAAGCCGATCAGACCCGTGGCGAGTACCCCGTTCTGGCTCAGGAATTCGAGCAAAGCCGGACCCCGGCCAGTGGCCACATCGACAAACACGATGTTGGTCTGCGCAGAGCGCACCTTCAGTCCATTGACGTCTTTCAGGCCATCGGCCAGCCGGGTGGCCAAACCATGGTCGGCGGCCAGCCGGTCCACATGGTGGTCCAGCGCATGGTGTGCCGCTGCGGCCAGAAAACCCGCCTGGCGCAAGCCGCCGCCGGCCATTTTGCGCAGGCGGCGGGCGCGTTCGATCAGCTCGCGCGAACCACACAGCGCAGACCCCACTGGCGCGCCCAGGCCTTTGCTGAAACACACCGACAGGCTGTCGAAATGGTTGGCGATCTCGCGAACGCGCGCCATGGCGCCCTGCCCTGGCGCGGCCGAGGCCACCGCCGCATTAAAAACGCGCGCACCATCGAGATGGGTCGCCAAGCCGTGGTCGCGCGCCAGTTGTGTTGCCTCATGCAAGTAACCGTCCGGCATCACGTTGCCATTCCAGGTGTTCTCCAGGCACAGCAACCGCGTGCGCGCAAAGTGCATGTCATCCGGCTTGATGGCCGCTGCAATATCCGCTAGCGCCATGCGCCCCGCGACGTCCTGCACCAACGGCTGCGGCTGCACGCTGCCGAACACCGCTGCGCCCCCGCCTTCAAAGCGGTAGGTGTGCGCGTTCTGACCAACGATGTATTCGTCGCCGCGCTGGCAATGCGCGAGGATGCCGCAGAGATTGCTTTGCGTGCCCGAGGGCATGAACAGCGCGGCTTGTTTGCCCGTGATGGTGGCGATGTGGTCTTGCAGCGCGTTGACCGTCGGGTCGTCGCCAAACACATCGTCGCCCAAGGGCGCGGCCATCATCGCGGCGCGCATGGCAGGCGTGGGTTGCGTGACGGTGTCGCTGCGCAAGTCAACGGTTTTCATGGCCGCTCCAGGAAGTTTTTCAGTTGGGCGTGACCGTGCTCGGTCAGGATGCTTTCCGGGTGGTATTGCATGCCCTCGATGTCCAGCGTCTTGTGTTTCACGCCCATTATTTCACCGTCGTCCGTCCAGGCCGTGACCGTGAGGCAGTCAGGCAAAGTGGCCCGCTCGATGGCGAGTGAGTGGTAGCGGTTCACTGTGAATCGCTCGGGAAGGTTCGCGAACACACCTTCCTGTGTGGTCGTGACAACGCTGGTTTTGCCGTGCATCAACTCCTTGGCGCGCACGATCTTGCCGCCGAAGGCTGCGCCAATGGCCTGGTGCCCCAGGCACACGCCGAGAATCGGCAGCTTGCCAGCGAAATGCTCGATGGTTGCCACCGAGATGCCGGCCTCAGCAGGAGAGCAAGGGCCCGGCGAGATCACCAGGCGGTCGACCTCGCCGGCGTCCACGCGGCGCTGGATCTCCTCAACGGTGATCTCATCGTTGCGCACCACGGTCACGTCTGCGCCAAGCTCACCGAAGTACTGCACGATGTTGTAGGTGAACGAGTCGTAGTTGTCCACCATGAGGAGTTTGATCTTCTTGCTCATGGCGCTCACTCCAGCCCTTCTTCGACCAGCTCGGCAGCGCGCAGCAGCGCACGCGCCTTGTGTTCGGTTTCCCTCCACTCCATCTCGGGAACCGAGTCGGCCACAACGCCGGCGGCGGCCTGCACGTGCAACACCTGGTCTTTGATGATGCCGGTACGGATCGCGATGGCCACGTCCATGTCACCCGCGTAGCTGAGATAACCGCAGGCGCCGCCATAGAGGCCGCGCTTGGTGGGCTCCAGCTGGTCGATCAGTTCCATGGCGTGCACCTTGGGCGCGCCAGTCAGCGTGCCGGCGGGGAAAGTGGCTTTGAGCACATCCATGTTGGTCATGCCGTCGTTCAGGATGCCTTCGACGTTGCTCACGATGTGCATCACATGGCTGTAGCGCTCGACCGCAAAGGCTTCCGTCACCTTGACCGAGCCGGTCTTGGCGATGCGCCCGATGTCGTTGCGCGCCAGGTCGATCAACATCACATGTTCGGCACGCTCTTTCGGGTCGTTCACCAGTTCTTGCTCGACCGCTTTGTCGGCTTCGGGCGACGCGCCGCGCGGGCGGGTTCCTGCCAGCGGGCGAATGGTGACCTTGGTGCCCTCCTCCGTGTGTTCCTGGCGAACCAGAATTTCCGGCGACGCGCCCACCACGTGGAAATCCCCGAAATGGTAGTAGTACATGTAGGGGCTGGGGTTCAGTGAACGCAGCGCGCGGTACAGGCTCAGCGGGCTTTCGGTGTAGCGCTTGCTGATGCGCTGGCCGACCTGCACCTGCATGAAATCGCCCGCCGCGATCAGTTCCTTGGCGCGGTCCACCGCAGCAAGGTAATCGACCTTGGAAAAACTGCGCTCGGCAGGGTAACTCTGCGTGGCTTTCACCACCGGCGCGCTGACGGAGTACTTCAACGCCTCTTTCAGTTCGCGCAAACGCTTCTTGGCATTGGCATAGGCCTCAGGCGCAGCCGGATCGGCGTAGACGATGAGATACAGCTTGCCCGACAGGTTGTCGATCACCGCCAACTCCTCGCACTGCAGCAACAGAATGTCGGGGCAGCCCAGCGCGTCTGGAGGGCAGCTGTTTTCCAGTTTCTTCTCGATATAGCGCACAGCGTCGTACCCGAAGTACCCCGCCAGCCCGCCGCAAAACCGCGGCAAGCCAGGGCGCAGCGCCACCTTGAAGCGCTGCTGGTACTCGGCAATGAAATCCAGCGGGTTACCCGTTGCGGTCTCCATGACCGCGCCATCGGTCACGACCTCGGTTTTTGCGTCAGAGCCAAAACCGCTGGCGCGCAGCAGCGTGCGGGCCGGCAGCCCTATGAAACTGTAGCGACCAAAGCGCTCGCCTCCCACGACAGACTCCAGCAAAAACGAGTGTTTGCCGTCGCCTTTGCCGTGCGCGAGCTTGAGGTACAGCGAGAGGGGGGTTTCCAGATCCGCAAAGGCCTCCACCATCAGTGGAATGCGGTTGTAGCCCTGGCTGGCCAGGCTCTTGAATTCAAGTTCGGTAATCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP017476|4639928:4648283|4642383_4643184_-|WP_066095899.1|DBSCAN-SWA
MNDILQKIVAVKHEEIAAALAKKPLQAMRFDAESRVLTRDFEAALRAKIAKSQAAVIAEVKKASPSKGVLRSDFIPADIAQSYAEGDGQVSAACLSVLTDRQFFQGSTDYLKQARASCDLPVLRKDFMVDPYQVYEARFMGADAILLIAACLDDAQMADLEAIAQGLNMAVLVEVHDRAELHRALKLQTPLLGINNRNLRTFEVSLQTTLDLMSDVPPDRLLITESGILGRNDVMRMREAGVHGFLVGEAFMRAPEPGLALAELFA
>NZ_CP017476|4639928:4648283|4646184_4646778_-|WP_082877170.1|DBSCAN-SWA
MSKKIKLLMVDNYDSFTYNIVQYFGELGADVTVVRNDEITVEEIQRRVDAGEVDRLVISPGPCSPAEAGISVATIEHFAGKLPILGVCLGHQAIGAAFGGKIVRAKELMHGKTSVVTTTQEGVFANLPERFTVNRYHSLAIERATLPDCLTVTAWTDDGEIMGVKHKTLDIEGMQYHPESILTEHGHAQLKNFLERP
>NZ_CP017476|4639928:4648283|4644440_4645094_-|WP_066095902.1|DBSCAN-SWA
MPDTAHLLVFIAAGWLLNLTPGPDVLYIVNTALKGGVRAGVVAALGIVSGCFVHVFAAAFGVGALLATSATAFTVLKWGGAAYLVWMGVKLLMASQGVSSGMTPAPTQSPQPVSLVTLYQRGFLTNVLNPKVALFFLAFVPQFIAHDAPNKVAAFLLLGLLFNINSLPVNFAYAWLAARAAQRLQTVQRAMRWMDRVAGLMFVGFGLKLAMSDNPSA
>NZ_CP017476|4639928:4648283|4645108_4646188_-|WP_066095905.1|DBSCAN-SWA
MKTVDLRSDTVTQPTPAMRAAMMAAPLGDDVFGDDPTVNALQDHIATITGKQAALFMPSGTQSNLCGILAHCQRGDEYIVGQNAHTYRFEGGGAAVFGSVQPQPLVQDVAGRMALADIAAAIKPDDMHFARTRLLCLENTWNGNVMPDGYLHEATQLARDHGLATHLDGARVFNAAVASAAPGQGAMARVREIANHFDSLSVCFSKGLGAPVGSALCGSRELIERARRLRKMAGGGLRQAGFLAAAAHHALDHHVDRLAADHGLATRLADGLKDVNGLKVRSAQTNIVFVDVATGRGPALLEFLSQNGVLATGLIGLRFVTHLDVDAAGIDHALTTIRRFFAELPAVPPAGAAAGSAVY
>NZ_CP017476|4639928:4648283|4643361_4644423_-|WP_066096212.1|DBSCAN-SWA
MPNAQKITPQEALQRTIEHREIFHDEMLHLMRMIMSGEMSPVMMAALITGLRVKKETIGEITAAAQVMREFSTKVNVPDKTHLVDIVGTGGDGSHTFNISTCSMFVAAAAGAKVSKHGGRSVSSKSGSADVLESLGININLPPEAIARCIEEVGVGFMFAPNHHPAMKAVAPVRKELGIKTIFNILGPLTNPASAPNILMGVFHPDLVGIQVRALQRLGAEHAVVVYGRDGMDEVSLGAATMVGELKDGEITEYEIHPEDFGFTMASNRALRVETPDESRAMLMGVLNNSDDPAIRPAIDIVVLNAGAALYAANVCGDMGEGIALARSAIESGAAASKLTELKSHTAASPASA
>NZ_CP017476|4639928:4648283|4641619_4642381_-|WP_066095893.1|DBSCAN-SWA
MPGARAGQRLLHWGEEPDPAAAPLWLTAVDPKAWPVAPDWQASVDAFWAEKVGQGLLHFLDGRLKAGAVIYPPEPLRALALTAPADVRVVILGQDPYHGPGQAEGLAFSVAPGIRLPPSLRNVFKELLRDLGLAPPSNGSLVRWAKQGVLLLNTCLTVEDGQPASHAGKGWESLTDTVIRCCSDRGPPKVFLLWGAHAQKKSVLIDGKRHCVLSANHPSPLSASRGPAPFFGCGHFSKTNRWLSEAGETEIHW
>NZ_CP017476|4639928:4648283|4646783_4648283_-|WP_066095908.1|DBSCAN-SWA
MITELEFKSLASQGYNRIPLMVEAFADLETPLSLYLKLAHGKGDGKHSFLLESVVGGERFGRYSFIGLPARTLLRASGFGSDAKTEVVTDGAVMETATGNPLDFIAEYQQRFKVALRPGLPRFCGGLAGYFGYDAVRYIEKKLENSCPPDALGCPDILLLQCEELAVIDNLSGKLYLIVYADPAAPEAYANAKKRLRELKEALKYSVSAPVVKATQSYPAERSFSKVDYLAAVDRAKELIAAGDFMQVQVGQRISKRYTESPLSLYRALRSLNPSPYMYYYHFGDFHVVGASPEILVRQEHTEEGTKVTIRPLAGTRPRGASPEADKAVEQELVNDPKERAEHVMLIDLARNDIGRIAKTGSVKVTEAFAVERYSHVMHIVSNVEGILNDGMTNMDVLKATFPAGTLTGAPKVHAMELIDQLEPTKRGLYGGACGYLSYAGDMDVAIAIRTGIIKDQVLHVQAAAGVVADSVPEMEWRETEHKARALLRAAELVEEGLE
>NZ_CP017476|4639928:4648283|4639928_4641119_-|WP_070263901.1|DBSCAN-SWA
MGKEKFTRSKPHVNVGTIGHVDHGKTTLTAAIATVLSKKFGGTAKAYDQIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPYIIVFLNKADMVDDAELLELVEMEVRELLTKYDFPGDDTPIIHGSAKLALEGDTGPLGEEAIMKLADALDTYIPMPERAVDGAFLMPVEDVFSISGRGTVVTGRIERGIVKVGEEIEIVGIADTQKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREDVQRGQVLCKPGTIKPHTHFTGEIYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPEGKEMVMPGDNVSITVKLINPIAMEEGLRFAIREGGRTVGAGVVAKIIA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_070263901.1|4639928_4641119_-	elongation factor Tu	A0A2H4UVR3	Bodo_saltans_virus	3.2e-11	24.1
WP_066095893.1|4641619_4642381_-	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	8.4e-50	47.1
WP_066095899.1|4642383_4643184_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.7e-61	53.2
WP_066096212.1|4643361_4644423_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	3.2e-79	46.9
WP_066095902.1|4644440_4645094_-	LysE family translocator	NA	NA	NA	NA
WP_066095905.1|4645108_4646188_-	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_082877170.1|4646184_4646778_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	9.1e-68	63.4
WP_066095908.1|4646783_4648283_-	anthranilate synthase component I	S4VT78	Pandoravirus	1.2e-36	28.9