CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP013018	Clostridium pasteurianum DSM 525 = ATCC 6013 chromosome, complete genome	3 crisprs	csa3,RT,c2c9_V-U4,cas3,DinG,cas2,cas1,cas4,cas5,cas7b,cas8b1,WYL,DEDDh	0	3	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP013018_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013018_1

699973-700532

Orphan

III-B

Consensus_repeat	Method
GTTGAACCTTAACATAGGATGTATTTAAAT	PILER-CR
GTTGAACCTTAACATAGGATGTATTTAAAT	CRISPRCasFinder
GTTGAACCTTAACATAGGATGTATTTAAAT	CRT

8 spacers

The CRISPR arrays of NZ_CP013018_1

>merge|NZ_CP013018|1|699973-700532|PILER-CR,CRISPRCasFinder,CRT
GTTGAACCTTAACATAGGATGTATTTAAATCAGATAATGCTACATGGAGAGGGGCTATAACACAAGGTTGAACCTTAACATAGGATGTATTTAAATTAATCATTATTTTCTCCTAACCAAATTCCATATTTCGTTGAACCTTAACATAGGATGTATTTAAATATATCAGGACAGTCATCTAATCTGCTAGTGTTTAGGTTGAACCTTAACATAGGATGTATTTAAATTGGAATAGTTAATACACAACTTACTTTTGAAGATTTGTTGAACCTTAACATAGGATGTATTTAAATTAATAATACCTTCCTGCAAATTCATAATTTTTTTGAGTTGAACCTTAACATAGGATGTATTTAAATTAATTTGGAAAACCTATATGAAAAGAGGATAGTGCAGTTGAACCTTAACATAGGATGTATTTAAATACAGCAGTTGCAAATAATGCAACTGCTACAGTACGTTGAACCTTAACATAGGATGTATTTAAATCTACTTGGTTAAATGAATTAAGGAGAGAATAATAAGATATGGTTGAACCTTAACATAGGATGTATTTAAAC

>NZ_CP013018|1|1|699973-700532|PILER-CR
GTTGAACCTTAACATAGGATGTATTTAAAT	CAGATAATGCTACATGGAGAGGGGCTATAACACAAG
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATCATTATTTTCTCCTAACCAAATTCCATATTTC
GTTGAACCTTAACATAGGATGTATTTAAAT	ATATCAGGACAGTCATCTAATCTGCTAGTGTTTAG
GTTGAACCTTAACATAGGATGTATTTAAAT	TGGAATAGTTAATACACAACTTACTTTTGAAGATTT
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATAATACCTTCCTGCAAATTCATAATTTTTTTGA
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATTTGGAAAACCTATATGAAAAGAGGATAGTGCA
GTTGAACCTTAACATAGGATGTATTTAAAT	ACAGCAGTTGCAAATAATGCAACTGCTACAGTAC
GTTGAACCTTAACATAGGATGTATTTAAAT	CTACTTGGTTAAATGAATTAAGGAGAGAATAATAAGATATG
GTTGAACCTTAACATAGGATGTATTTAAAC

>NZ_CP013018|1|1|699973-700532|CRISPRCasFinder
GTTGAACCTTAACATAGGATGTATTTAAAT	CAGATAATGCTACATGGAGAGGGGCTATAACACAAG
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATCATTATTTTCTCCTAACCAAATTCCATATTTC
GTTGAACCTTAACATAGGATGTATTTAAAT	ATATCAGGACAGTCATCTAATCTGCTAGTGTTTAG
GTTGAACCTTAACATAGGATGTATTTAAAT	TGGAATAGTTAATACACAACTTACTTTTGAAGATTT
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATAATACCTTCCTGCAAATTCATAATTTTTTTGA
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATTTGGAAAACCTATATGAAAAGAGGATAGTGCA
GTTGAACCTTAACATAGGATGTATTTAAAT	ACAGCAGTTGCAAATAATGCAACTGCTACAGTAC
GTTGAACCTTAACATAGGATGTATTTAAAT	CTACTTGGTTAAATGAATTAAGGAGAGAATAATAAGATATG
GTTGAACCTTAACATAGGATGTATTTAAAC

>NZ_CP013018|1|1|699973-700532|CRT
GTTGAACCTTAACATAGGATGTATTTAAAT	CAGATAATGCTACATGGAGAGGGGCTATAACACAAG
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATCATTATTTTCTCCTAACCAAATTCCATATTTC
GTTGAACCTTAACATAGGATGTATTTAAAT	ATATCAGGACAGTCATCTAATCTGCTAGTGTTTAG
GTTGAACCTTAACATAGGATGTATTTAAAT	TGGAATAGTTAATACACAACTTACTTTTGAAGATTT
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATAATACCTTCCTGCAAATTCATAATTTTTTTGA
GTTGAACCTTAACATAGGATGTATTTAAAT	TAATTTGGAAAACCTATATGAAAAGAGGATAGTGCA
GTTGAACCTTAACATAGGATGTATTTAAAT	ACAGCAGTTGCAAATAATGCAACTGCTACAGTAC
GTTGAACCTTAACATAGGATGTATTTAAAT	CTACTTGGTTAAATGAATTAAGGAGAGAATAATAAGATATG
GTTGAACCTTAACATAGGATGTATTTAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013018.1\|WP_004455533.1\|711311_712232_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133028
NZ_CP013018.1\|WP_004455544.1\|702021_703002_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_CP013018.1\|WP_034829284.1\|697734_698994_-\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NZ_CP013018.1\|WP_004455389.1\|694718_695987_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_004455543.1\|703596_704265_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|274398
NZ_CP013018.1\|WP_004455387.1\|694509_694707_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_004455384.1\|692394_693102_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_003448320.1\|696912_697719_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|132060
NZ_CP013018.1\|WP_004455385.1\|693172_693652_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_004455542.1\|704302_705610_+\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223936
NZ_CP013018.1\|WP_004455541.1\|705635_706685_+\|mannose-1-phosphate-guanylyltransferase	unknown	unknown	gnl\|CDD\|223906
NZ_CP013018.1\|WP_004455539.1\|707824_709033_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340850
NZ_CP013018.1\|WP_004455382.1\|690571_690931_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_004455537.1\|709076_710120_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NZ_CP013018.1\|WP_004455545.1\|700768_701941_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|366353
NZ_CP013018.1\|WP_034829769.1\|706699_707812_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340833
NZ_CP013018.1\|WP_004455383.1\|691257_692283_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_CP013018.1\|WP_004455386.1\|693919_694522_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_004455535.1\|710134_711142_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|224137
NZ_CP013018.1\|WP_004455390.1\|695987_696293_+\|DUF4325-domain-containing-protein	unknown	unknown	gnl\|CDD\|379507

Protein	Function_ID	Function_description	E-value
NZ_CP013018.1\|WP_004455544.1\|702021_703002_-\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	3.89414e-52
NZ_CP013018.1\|WP_034829284.1\|697734_698994_-\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.26072e-22
NZ_CP013018.1\|WP_004455533.1\|711311_712232_+\|glycosyltransferase	gnl\|CDD\|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.45448e-59
NZ_CP013018.1\|WP_004455543.1\|703596_704265_+\|sugar-transferase	gnl\|CDD\|274398	TIGR03025, EPS_sugtrans, exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase. Members of this family are generally found near other genes involved in the biosynthesis of a variety of exopolysaccharides. These proteins consist of two fused domains, an N-terminal hydrophobic domain of generally low conservation and a highly conserved C-terminal sugar transferase domain (pfam02397). Characterized and partially characterized members of this subfamily include Salmonella WbaP (originally RfbP), E. coli WcaJ, Methylobacillus EpsB, Xanthomonas GumD, Vibrio CpsA, Erwinia AmsG, Group B Streptococcus CpsE (originally CpsD), and Streptococcus suis Cps2E. Each of these is believed to act in transferring the sugar from, for instance, UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate as the first (priming) step in the synthesis of an oligosaccharide "block". This function is encoded in the C-terminal domain. The liposaccharide is believed to be subsequently transferred through a "flippase" function from the cytoplasmic to the periplasmic face of the inner membrane by the N-terminal domain. Certain closely related transferase enzymes, such as Sinorhizobium ExoY and Lactococcus EpsD, lack the N-terminal domain and are not found by this model.	5.1415e-101
NZ_CP013018.1\|WP_003448320.1\|696912_697719_-\|AAA-family-ATPase	gnl\|CDD\|132060	TIGR03015, pepcterm_ATPase, putative secretion ATPase, PEP-CTERM locus subfamily. Members of this protein are marked as probable ATPases by the nucleotide binding P-loop motif GXXGXGKTT, a motif DEAQ similar to the DEAD/H box of helicases, and extensive homology to ATPases of MSHA-type pilus systems and to GspA proteins associated with type II protein secretion systems. [Protein fate, Protein and peptide secretion and trafficking].	5.11527e-40
NZ_CP013018.1\|WP_004455542.1\|704302_705610_+\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl\|CDD\|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP013018.1\|WP_004455541.1\|705635_706685_+\|mannose-1-phosphate-guanylyltransferase	gnl\|CDD\|223906	COG0836, {ManC}, Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane].	5.88996e-153
NZ_CP013018.1\|WP_004455535.1\|710134_711142_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	9.50645e-18
NZ_CP013018.1\|WP_004455537.1\|709076_710120_+\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.26478e-17
NZ_CP013018.1\|WP_004455545.1\|700768_701941_+\|C40-family-peptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.61606e-31
NZ_CP013018.1\|WP_034829769.1\|706699_707812_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340833	cd03804, GT4_WbaZ-like, mannosyltransferase WbaZ and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.	0
NZ_CP013018.1\|WP_004455383.1\|691257_692283_-\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	6.51521e-36
NZ_CP013018.1\|WP_004455539.1\|707824_709033_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340850	cd03823, GT4_ExpE7-like, glycosyltransferase ExpE7 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).	3.29575e-83
NZ_CP013018.1\|WP_004455390.1\|695987_696293_+\|DUF4325-domain-containing-protein	gnl\|CDD\|379507	pfam14213, DUF4325, STAS-like domain of unknown function (DUF4325). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 99 and 341 amino acids in length. This domain is distantly related to the STAS domain.	0.0009836

>NZ_CP013018.1|WP_034829284.1|697734_698994_-|DDE-type-integrase/transposase/recombinase
MLKEFNQKIALFRYSLIAPIITNTFTQTSVKDYLAEIAAKSYTLPNGKKKEYSPATIKGWLVQYRKYGIDGLYPKSRADKGTSRKISNETKEFIINSKLNSPKKTAKYIYHEVIAKGFESETSISLSTVTRFINKAKIGSKKLVPDDRRAFEFEFSNECWQSDVSVGPYLTIEDKKFKTYIIAFLDDSSRVIVGCKAFFKDDLLSLMSVFKDAVASKGIPKKVFVDNGKIYKSEQFHLICAALGSILSFARPYSPQSKGKIERWFQTMQKQWMNSINWNDFKSIDLLNESLSGYVNSYNNTIHSSINKKPIDKYMSNVENIRFIDSKTELDYLFLYKVLRTVKNDSTVSIGTKIFEVPLKYVGDKINIRYDPSSIDKAYIFSQDGKLEDTIFPVKKIDNSKIRRTNNTNSVDFSAFEAN
>NZ_CP013018.1|WP_003448320.1|696912_697719_-|AAA-family-ATPase
MYKAFYGLTFDPFDKNLDLKYSFKSEDFSKAMNRLEFLKSVLGIGVITGEPGVGKSFLLRNFVDSLNPNLYKCVYIPISTLTVMDFYRALCDGLGIIHAQKKVTMFKQIQESIYTYSHSKNVIPVIIIDECQFLSNSILDDLRIIFNFHMDSKNYAMLILSGQPNFLLQLSRQVHEALRQRIIMNYCLKGLTHDECKPYITSMLKAAGCSEPIFTDDAFELIYSSTNGAIRPLNSLTRMCLISGANERLTSINSDTVYKSQSEIDLTI
>NZ_CP013018.1|WP_004455390.1|695987_696293_+|DUF4325-domain-containing-protein
MEKVIKVIDLLNSISADDDEKGNKVFNSIVNSANEKYDNIILNFEGISLINTAFLNNAMGKICGLEEFESGKVNVKVANFPKEAIELLREVLKTASEKYSK
>NZ_CP013018.1|WP_004455389.1|694718_695987_+|hypothetical-protein
MNCIIYFLTDYYQKSLRSLAQTQADSYEEVLDKYKKIFISHLNYVKNKKCNFESCKFGCNNECSNLKEIIKNIDVNKIQDFFDTIKKIYINWIDAKTSDSLNELKTLLHNFKMIDFKAEDITKELFFKGRLSEQILTTWQMFHIPFNKRYLISNQRYSLTGQPLIYLGKSVIDVVEELEVSQEQLSLLKVSTFEIKENLRVYDLRNDIYNDVINAKIESRILGNDSKEIINEGKFFKNILSSICSFQKRKEHRNFSFCEEYVLPQVLAQTLKNELFHGIIYHSTKKFNNINFEISSEEDSWIQYIKRTKYKENVALFTHFNDEHVYDRNLYEKLTISTPIDIAKLNTIKIDDLKNIQAEINQTKKQDMISICETLLSKFDREFSQCCINEKKYRETNIGQLHIYHLYSIFNRILTQCNEEVK
>NZ_CP013018.1|WP_004455387.1|694509_694707_+|hypothetical-protein
MAELNKWFYNEKNVNEIDISDSLIINSFFPGTLITISIDYDKNEGAYENYFVKEFDLFQIFNIKE
>NZ_CP013018.1|WP_004455386.1|693919_694522_+|hypothetical-protein
MNIYFPKSLKSDKKGIEFISYVWGKCKKIYSYKIFWNLRFTSNIETNLLSVLGIIIDKLMKKGNKIFIELRDNKGILRTISSNIIEELFMKYSEFKFKALQYKYINFSIVNNEIDKYLNEDLKELRLKEFEKVKIILSELIANIKMHASSKQGSISAFIDIKKDELVVSVCNIGKTIKQNIEEKVNYNFDNDLDAILWLN
>NZ_CP013018.1|WP_004455385.1|693172_693652_-|hypothetical-protein
MESKSYYSKRVNCIILSILCWVLIFLICTKVLNDPDMITDTAVIILRIVIVVLVVVGLTTFIKAVDKRPIVTISKEGIEIQSFIFSNIFIKWDELKGINREKYTQLVASSSLVGFSTNYMLRFHRKQGRSVAVNLSLLDTQNNDFFKTLGDYIKMYKNA
>NZ_CP013018.1|WP_004455384.1|692394_693102_-|hypothetical-protein
MKTYKLSPEGLNKSISKILLRIIPLSLLVLVAVLYMNSANNSTSITTFFIIVILIAVVLTISIQRGLKNQKESLLSYELVISDNSIVKKQLSLPTIEIEYSDIITIEEITYKGLIIKTKDKYKVIGIPYYLIGYEEVKNTLSQYADIKKSTTPSLIKTSQYVLPILVVLALIIIIKSNNKYLVLPFGTAYILLSLWFIIEIFRNTQLNSKLKQKYLFLIFPLLAVILKMIIIFSA
>NZ_CP013018.1|WP_004455383.1|691257_692283_-|LCP-family-protein
MKKKKIFVPIIVVLLIIAIIGGGAYLYIDSKLSKMKTTEISKKPSDLGIDTKQFDQNTSKDIDKNYVNILLMGSDSRDPDTDPGLVDSIMILTIDKAHNKLKLTSLMRDMLIDNVVGEGVTEGTTLDRINVIYKQGGGKNGGGQYSIKAINSNFDMNIKDYVKVDFTHFDRIIDAVGGIDMYVSSSEVDVANNYIREVAKINGVTPKLLTTGGMQHLNGIQALGYSRIRYVGRQDFQRTERQRAVLTQVFSRLASMNPAEASTALDTIFPDVETSLSKTDILSYITYVITNKITTINQFRLPEDKAGYSFSKYIKGTYFLGWDKDKNVADLHQFIFEGDLK
>NZ_CP013018.1|WP_004455382.1|690571_690931_+|hypothetical-protein
MILYHFSNGKCDRLIPNLSSKRQLTEGNTTKEKITILTTNPNMFYENDNGDNFFKYRYIVKLDENDPYLHADDKFNGMLEKHNRSFHSKRVAFKWFFYENPLDYSAISEWDKKLCKFME
>NZ_CP013018.1|WP_004455545.1|700768_701941_+|C40-family-peptidase
MNKKPIILLLAVAVSIGLILPAKYTYAATSHKTVISKSKSKPSPNLKSMTCIDTPRSGSFLNKNTLIGGWALNKSGVKEVQILVDGKFKGRAKIGISRQDVARVYPAYKNKNSGYNYILDYRSIGQGTHTITVKAIGKNNTSNTNSIKVNVNKLAPIVWIDTPTSGTNINKNFNVAGWALNGSGVKQVQVYVDNRLIGNAVIRKYRPDVARVFPKYNNRNSGYSLTISKDKIPSGNHTITVKVKGNDGVITSKSVKIKKAAPVSTKSSANKGQAVVNYAEKFKGIKYVWGGETPKGFDCSGYTKYVYNYFNIKLPHNAAQQYKYGKYVSKNSLKPGDLVFFGKTAGSIYHVGIYIGSGNYINEPKPGDKVKITVLRYMPDYYGAKRLISQ
>NZ_CP013018.1|WP_004455544.1|702021_703002_-|LCP-family-protein
MKKKVIIIPIFIILAFIIAFGAGTYFTINSKLSKLKTTNISKNATDLGIDTKQFNNTVEDNYVNILLLGVDTRDANTDTGRSDSIMILTLDKAHKKIKLTSLMRDLLVTNVGSKSQDKLTHAYAYGGPQLSLKVVNENFNMNIKDYVKVDFTHFDKIVDAVGGVDINVSDAEVKVLNGYITELAKLEKVTPQYLTSGGMQHLNGMQALAYARIRYVGDGDYQRTERQRTVLTQVFSKISSMGLTEASSMLDTILPNVETSLTKSDILSNTSYVLMNKINTVNQYRVPNDKPGYATNRMINGVFYLDWNREGNIADLHQFIFEGDLK
>NZ_CP013018.1|WP_004455543.1|703596_704265_+|sugar-transferase
MQNLELDKEVDVDLYRDRYSKSFLYYAGKRLIDICGSSIGLILLSPFLLVIIIAIKLDSKGPVIFSQERVGKNGRKFKMYKFRSMVVNAEELLIKLKDKNEMSGPMFKMKEDPRITKVGKFIRRTSIDELPQLLNVLKGDMSLVGPRPNLPREVAKFSDYHKLKLLAKPGLTCYWQVMGRNTIGFEEWMKLDIKYIEERNLWVDIKLIIRTFFMLFGDKNAH
>NZ_CP013018.1|WP_004455542.1|704302_705610_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MKIVVAGTGYVGLVTGACLSEVGHSVTCVDIDEKKVQLMKDGISPIYEPGLDELLKKNHEQGRLNFTTDYKAAYSDADVIFIGVGTPEKSDGSANLDYVYIVARQIAQNITRDCLVVVKSTVPIGTNDEVEEFLKDNLVKDVNIEVASNPEFLAQGTAVKDTLHAKRIVVGVESENAKNIMTEIYNRFNQPIVVTDRRSAEMIKYASNDFLALKISFVNEIANLCELVGANIEHVTEGMSYDTRIGDKFLKAGIGYGGSCFPKDTKALHWLADGWGYEIKTVKATIDVNENQKFRLIRKAKQKCKILKGLKVAVLGLTFKPGTDDLREAPSIPNVKMLLEEGAEVIAYDPVGEDNFKKLFPTEITYVQNPEEALKDADLAFLFTEWKEITGISLDKYKELMKKPVIFDGRNCYDLEEAEKAGVEYYSIGRPAVKS
>NZ_CP013018.1|WP_004455541.1|705635_706685_+|mannose-1-phosphate-guanylyltransferase
MLCALIMAGGKGERFWPLSTDEKPKQFLKLLGEETMIQMTVNRLKDLIPVERIFVVTGERYTKLVKEQLPELPQRNIIVEPMGKNTAPCIALSAFHIEKYYENATIAVLPSDHLIRNEEEFRNVIATADSFIEKHEDSIVTLGMKPDRAETGYGYIKCDKTDSIVKGLKIRNVEMFVEKPDEETAEEYLRDGNFLWNGGMFVWKAKNVLTLTEKYLKNTYDVLKEITCSLEEEYEEKLKTNYNLVDSVSIDYAIMEKAESIYVIPSEFGWDDVGTWYSVERYRDKDENNNVCVGNIININSKNNIIVGNNKPVIISGLDDIFVVESDDVILIGKKDDIKDIKDIKKTVL
>NZ_CP013018.1|WP_034829769.1|706699_707812_+|glycosyltransferase-family-4-protein
MKVALVHDWLTNMGGAERVVINFKEIYKDSPIYTTLYNPEKLDEELKNIDVRTSFLQNEKNLKKGHQSLLPFMPMAFESFDLNEYDIILSSSSSCAKGVVTNPNSMHVCYCHTPMRYGWEFYYEYANNWDMKKIKRNMLKYFINYIRVWDNVSSNRVDYFIANSQNVARRIWKHYRRESVVIHPPVRCKLFNISDIDEDYFLILSRLVPYKKVDLAVKAFNELGLPLVVIGDGVERQKLESIAKDNIKFLGRQPDSVIKEYYSKCRAFLFPGDEDFGITPLEAQASGRPVIAFGKGGALETVVENQTGVFFREQTVDSLKDAVKRFEGVKFDKQAIRKHAEEFDEEIFKEKIKSFIENSYVNFKKSFNVL
>NZ_CP013018.1|WP_004455539.1|707824_709033_+|glycosyltransferase-family-4-protein
MNILIVNTYYFPNIIGGAEISVKKLAEGLVANGHEVHIICTDVKDDNEIINGVNVHRIKLSNIYQPIELRNKNILKKMIGRINDIYNMFNRKKLKEAILEISPDIMHVNNIYGISPAIWNLAKDMEIKLVHTIRDYYLMCPKISMLKENKICNKKNIVCKVFCNINRNISNKVDFVTAPSQYTLDTFINDGFFNLSKKEKVFNAIDFDQKMVREIYFSKNFNISNDKIIKFVFMGSLNKNKGIDLLLKAFSEVRNKEIELIIAGKGPLEQMVNEYCNMDKRIHYKGFLREEKINAILRESHVLVAPSVWNEPFGRVVIDAYKNCMPVIAGNYGGLKEIVKNDFTGKLIEPNNKNEFIKTIEYFTNRSIIKQMLKNCMDELAEYSIQKQVEHFENIYKICLED
>NZ_CP013018.1|WP_004455537.1|709076_710120_+|glycosyltransferase
MKTCFCPYESKLNKYVEIIQDCLKLKNIEVYSIKSVLSNRKLFKEVSIYNFNWFENVDKSKIKMIPKIICKILFIKYLRIKKKKIIWTMHNKEPHNSKNNLLAQFMIKFMAVNSQKIVVLSNESKVTLKKFISEEEIEKKVKLIAHPNYLGSYKNSKVDDISNNNYLNLLFIGRVQPYKNIELLIDVSNSFYNKNVNFIIAGKPNTSEYGEMLKKSIKNKNIKTKFSFIEDEEMISLIKMSDAIILPYDIQSSLNSGTIMLAFSNKKTVISPLIGTLKDIKNENLYFTYEYSSQEEHKKKLKEAIINVTKKSRVEIRNMGERCFDYVKEHNSKELIAEKYEELYNNL
>NZ_CP013018.1|WP_004455535.1|710134_711142_+|glycosyltransferase-family-2-protein
MKKVVPIVIIEFNSYARTIKYIYDFLDSVIYEKVSFIIVDNGDSDNNYNSIKKEIKNKFESKYELNILENNDKRIKKAIKIIVKIKDIYIVDIVLIKAKENYGFAIGNNIGVSIAEKIYKVDHIIFSNSDIRFNESFNLKKLIEKLKSDSQIALVGPKIIGLDNEAQTPCEEKTIMERWNLLSIVWPLNRIFKIKFLNTSDDVIHINENYIPYRILGAFMLFDFKKFLEINMFDENTFLYAEELIIAEKLKQLDYKTYYCNSQILIHEQGGTTKKVLNNINKIKLRFNSEMYYYSRYKKVNNKIIFITKVLFNFYIFKLNIYHYFQNKFMKKINL
>NZ_CP013018.1|WP_004455533.1|711311_712232_+|glycosyltransferase
MKIGIIIVTYNRKECLLKSLKLYEQQSKLPSYILVVNNNSNDGTEKVLNDWKNDEKHFKKYVINLNNNIGGSGGFYTGLKKGLELDADWIWVSDDDAYPEKDALENIYKYVKSNDEKTIHKISTICGQVINNNKIDESHRKRLKKSFLKIDFIPVNKNEYDKESFELELFSYVGSAINKRYLKQAGLPEKDYFIYYDDTEHSYRLSKKGKIICLPSVKIIHDVDSRTSCDVDWKKYYGMRNRLLFLKKHFNIRYYIYSYVTQIIKCAIRDIIKSSLIENVQIRDALKDSRQNVLGLHSKYKPGWKP

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Crispr_ID: NZ_CP013018_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013018_2

2832672-2835133

TypeI-B

III-B

Consensus_repeat	Method
GTTGAACCTTAACATAGGATGTATTTAAAT	PILER-CR
ATTTAAATACATCCTATGTTAAGGTTCAAC	CRISPRCasFinder
ATTTAAATACATCCTATGTTAAGGTTCAAC	CRT

37 spacers

cas8b1,cas7b,cas5,cas3,cas4,cas1,cas2

The CRISPR arrays of NZ_CP013018_2

>merge|NZ_CP013018|2|2832672-2835133|PILER-CR,CRISPRCasFinder,CRT
ATTTAAATACATCCTATGTTAAGGTTCAACGGTGGTAGTTTAGATACAGATATAAGTCAATATGTAATTTAAATACATCCTATGTTAAGGTTCAACTGATGCTAAAGTTGCATTAACAATCATTTTTTGTGCATTTAAATACATCCTATGTTAAGGTTCAACATGCAATTTTATACCAAATGCCGCAGATATTTGTATTTAAATACATCCTATGTTAAGGTTCAACTATACTTTTATAATTTCATCCTTTGTAACACCTTCCATTTAAATACATCCTATGTTAAGGTTCAACCATAGATAAATTCACCTACCTTTCTATTTTTGTTTTATTTAAATACATCCTATGTTAAGGTTCAACGTAGAAGAATATGAGCTCTTTACAAGTTCATTAATTATTTAAATACATCCTATGTTAAGGTTCAACCATCTCTGCCAGTGCTATGTTTGCAATTGGTAAAGAATTTAAATACATCCTATGTTAAGGTTCAACTATTTAACTTCTGAACACTCTTCAATCCATATTATATTTAAATACATCCTATGTTAAGGTTCAACCCACTAAATAAATAAACTCTATCGCCATCTTGTTTGGATTTAAATACATCCTATGTTAAGGTTCAACATTTAGGTGATTGCCAAGTTCCGTTGGAGTTCCAAGATTTAAATACATCCTATGTTAAGGTTCAACTTTATATTCAAAACTAATTCCTTTTTAGTCATTACTATTTAAATACATCCTATGTTAAGGTTCAACTACAAATAAATTCAATTCTTCCGTAGAAAATGAAAATTTAAATACATCCTATGTTAAGGTTCAACTCAATACATATCTCTTTGGTATAATTAGCTTCTCATTTAAATACATCCTATGTTAAGGTTCAACACATATGAGTATGGTCTTTATCACATTCTATTGCAAATTTAAATACATCCTATGTTAAGGTTCAACAAAAACAAGAAACAAGTCTTATCAAATATGAAATGTCATTTAAATACATCCTATGTTAAGGTTCAACTGATTTTTCATCGCCAAGATCAGCATACCAAATTTGCATTTAAATACATCCTATGTTAAGGTTCAACGTACTATTAGCAACTGCAACATCTTCTTCAACTTTTATTTAAATACATCCTATGTTAAGGTTCAACTATAATGTATGCTTTGGTATTGCACCTATCCTATTTATTTAAATACATCCTATGTTAAGGTTCAACACTTTTTCTATCTCAGTCCAATACACAGTAATAATATTTAAATACATCCTATGTTAAGGTTCAACTTTCTTCATCGCAATGAGGACAATCAAATTTTACATTTAAATACATCCTATGTTAAGGTTCAACAAATCACTTCAACTTCCTCACTGTTTACAGTTACAAATTTAAATACATCCTATGTTAAGGTTCAACCCTTTTTCTGTCAAGTTCTTTTTTTATTTTTTCACAATTTAAATACATCCTATGTTAAGGTTCAACCAAACTGGCTAGAAGAAACGAAACGGATGTAATAAATTTAAATACATCCTATGTTAAGGTTCAACAAGAAGTGATTCTTCATCCTGATAATTCCACTTAGTATTTAAATACATCCTATGTTAAGGTTCAACTATCTATTGTTACTGGTGTAGCTTTACCTGCTAGCATTTAAATACATCCTATGTTAAGGTTCAACTATTCTTTAAAATGTCTTTTGTGTTTAATACATTATATTTAAATACATCCTATGTTAAGGTTCAACAAACAAAGGTTAATAGCTTAGCTTTTGTTTTGAGGATTTAAATACATCCTATGTTAAGGTTCAACTTACCTGTTACACTAAATTCATCAACCAAGATTTTATTTAAATACATCCTATGTTAAGGTTCAACTTACTTTTTCTCTGCTGTTAGACGGTATATCAACGCAATTTAAATACATCCTATGTTAAGGTTCAACCAGTTTGCCTTTAATTCTTGTTTCTTGCCATTCACTATTTAAATACATCCTATGTTAAGGTTCAACACTAGATGCTCTCTACAAGATATTGAGTTCACATATATTTAAATACATCCTATGTTAAGGTTCAACGGTAAGGAGCATAAGAGCATAGATAAAGATGACTGATTTAAATACATCCTATGTTAAGGTTCAACCCAACTATACCATCTACAGGAAGATGCAATATAGTCATTTAAATACATCCTATGTTAAGGTTCAACGCTGACTGGCATTTAATTTTTTAGCAATTTCGACCTGATTTAAATACATCCTATGTTAAGGTTCAACCTGTGGTACTTACCTTTAAAGCAATGCTGTTACTCAAATTTAAATACATCCTATGTTAAGGTTCAACGGAGTAAGACCACCAGTAATTGCAATCCCTGTCCAATTTAAATACATCCTATGTTAAGGTTCAACTAGAGCAAGGTAATGTAATTTAGATACTTAAAATTATTTAAATACATCCTATGTTAAGGTTCAAC

>NZ_CP013018|2|2|2832672-2835133|PILER-CR
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGTGGTAGTTTAGATACAGATATAAGTCAATATGTA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TGATGCTAAAGTTGCATTAACAATCATTTTTTGTGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ATGCAATTTTATACCAAATGCCGCAGATATTTGT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATACTTTTATAATTTCATCCTTTGTAACACCTTCC
ATTTAAATACATCCTATGTTAAGGTTCAAC	CATAGATAAATTCACCTACCTTTCTATTTTTGTTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	GTAGAAGAATATGAGCTCTTTACAAGTTCATTAATT
ATTTAAATACATCCTATGTTAAGGTTCAAC	CATCTCTGCCAGTGCTATGTTTGCAATTGGTAAAGA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATTTAACTTCTGAACACTCTTCAATCCATATTAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCACTAAATAAATAAACTCTATCGCCATCTTGTTTGG
ATTTAAATACATCCTATGTTAAGGTTCAAC	ATTTAGGTGATTGCCAAGTTCCGTTGGAGTTCCAAG
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTTATATTCAAAACTAATTCCTTTTTAGTCATTACT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TACAAATAAATTCAATTCTTCCGTAGAAAATGAAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TCAATACATATCTCTTTGGTATAATTAGCTTCTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACATATGAGTATGGTCTTTATCACATTCTATTGCAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAAAACAAGAAACAAGTCTTATCAAATATGAAATGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	TGATTTTTCATCGCCAAGATCAGCATACCAAATTTGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GTACTATTAGCAACTGCAACATCTTCTTCAACTTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATAATGTATGCTTTGGTATTGCACCTATCCTATTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACTTTTTCTATCTCAGTCCAATACACAGTAATAAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTTCTTCATCGCAATGAGGACAATCAAATTTTAC
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAATCACTTCAACTTCCTCACTGTTTACAGTTACAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCTTTTTCTGTCAAGTTCTTTTTTTATTTTTTCACA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CAAACTGGCTAGAAGAAACGAAACGGATGTAATAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAGAAGTGATTCTTCATCCTGATAATTCCACTTAGT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATCTATTGTTACTGGTGTAGCTTTACCTGCTAGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATTCTTTAAAATGTCTTTTGTGTTTAATACATTAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAACAAAGGTTAATAGCTTAGCTTTTGTTTTGAGG
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTACCTGTTACACTAAATTCATCAACCAAGATTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTACTTTTTCTCTGCTGTTAGACGGTATATCAACGCA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CAGTTTGCCTTTAATTCTTGTTTCTTGCCATTCACT
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACTAGATGCTCTCTACAAGATATTGAGTTCACATAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGTAAGGAGCATAAGAGCATAGATAAAGATGACTG
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCAACTATACCATCTACAGGAAGATGCAATATAGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GCTGACTGGCATTTAATTTTTTAGCAATTTCGACCTG
ATTTAAATACATCCTATGTTAAGGTTCAAC	CTGTGGTACTTACCTTTAAAGCAATGCTGTTACTCAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGAGTAAGACCACCAGTAATTGCAATCCCTGTCCA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TAGAGCAAGGTAATGTAATTTAGATACTTAAAATT
ATTTAAATACATCCTATGTTAAGGTTCAAC

>NZ_CP013018|2|2|2832672-2835133|CRISPRCasFinder
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGTGGTAGTTTAGATACAGATATAAGTCAATATGTA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TGATGCTAAAGTTGCATTAACAATCATTTTTTGTGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ATGCAATTTTATACCAAATGCCGCAGATATTTGT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATACTTTTATAATTTCATCCTTTGTAACACCTTCC
ATTTAAATACATCCTATGTTAAGGTTCAAC	CATAGATAAATTCACCTACCTTTCTATTTTTGTTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	GTAGAAGAATATGAGCTCTTTACAAGTTCATTAATT
ATTTAAATACATCCTATGTTAAGGTTCAAC	CATCTCTGCCAGTGCTATGTTTGCAATTGGTAAAGA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATTTAACTTCTGAACACTCTTCAATCCATATTAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCACTAAATAAATAAACTCTATCGCCATCTTGTTTGG
ATTTAAATACATCCTATGTTAAGGTTCAAC	ATTTAGGTGATTGCCAAGTTCCGTTGGAGTTCCAAG
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTTATATTCAAAACTAATTCCTTTTTAGTCATTACT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TACAAATAAATTCAATTCTTCCGTAGAAAATGAAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TCAATACATATCTCTTTGGTATAATTAGCTTCTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACATATGAGTATGGTCTTTATCACATTCTATTGCAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAAAACAAGAAACAAGTCTTATCAAATATGAAATGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	TGATTTTTCATCGCCAAGATCAGCATACCAAATTTGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GTACTATTAGCAACTGCAACATCTTCTTCAACTTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATAATGTATGCTTTGGTATTGCACCTATCCTATTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACTTTTTCTATCTCAGTCCAATACACAGTAATAAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTTCTTCATCGCAATGAGGACAATCAAATTTTAC
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAATCACTTCAACTTCCTCACTGTTTACAGTTACAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCTTTTTCTGTCAAGTTCTTTTTTTATTTTTTCACA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CAAACTGGCTAGAAGAAACGAAACGGATGTAATAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAGAAGTGATTCTTCATCCTGATAATTCCACTTAGT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATCTATTGTTACTGGTGTAGCTTTACCTGCTAGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATTCTTTAAAATGTCTTTTGTGTTTAATACATTAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAACAAAGGTTAATAGCTTAGCTTTTGTTTTGAGG
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTACCTGTTACACTAAATTCATCAACCAAGATTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTACTTTTTCTCTGCTGTTAGACGGTATATCAACGCA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CAGTTTGCCTTTAATTCTTGTTTCTTGCCATTCACT
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACTAGATGCTCTCTACAAGATATTGAGTTCACATAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGTAAGGAGCATAAGAGCATAGATAAAGATGACTG
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCAACTATACCATCTACAGGAAGATGCAATATAGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GCTGACTGGCATTTAATTTTTTAGCAATTTCGACCTG
ATTTAAATACATCCTATGTTAAGGTTCAAC	CTGTGGTACTTACCTTTAAAGCAATGCTGTTACTCAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGAGTAAGACCACCAGTAATTGCAATCCCTGTCCA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TAGAGCAAGGTAATGTAATTTAGATACTTAAAATT
ATTTAAATACATCCTATGTTAAGGTTCAAC

>NZ_CP013018|2|2|2832672-2835133|CRT
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGTGGTAGTTTAGATACAGATATAAGTCAATATGTA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TGATGCTAAAGTTGCATTAACAATCATTTTTTGTGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ATGCAATTTTATACCAAATGCCGCAGATATTTGT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATACTTTTATAATTTCATCCTTTGTAACACCTTCC
ATTTAAATACATCCTATGTTAAGGTTCAAC	CATAGATAAATTCACCTACCTTTCTATTTTTGTTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	GTAGAAGAATATGAGCTCTTTACAAGTTCATTAATT
ATTTAAATACATCCTATGTTAAGGTTCAAC	CATCTCTGCCAGTGCTATGTTTGCAATTGGTAAAGA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATTTAACTTCTGAACACTCTTCAATCCATATTAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCACTAAATAAATAAACTCTATCGCCATCTTGTTTGG
ATTTAAATACATCCTATGTTAAGGTTCAAC	ATTTAGGTGATTGCCAAGTTCCGTTGGAGTTCCAAG
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTTATATTCAAAACTAATTCCTTTTTAGTCATTACT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TACAAATAAATTCAATTCTTCCGTAGAAAATGAAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TCAATACATATCTCTTTGGTATAATTAGCTTCTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACATATGAGTATGGTCTTTATCACATTCTATTGCAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAAAACAAGAAACAAGTCTTATCAAATATGAAATGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	TGATTTTTCATCGCCAAGATCAGCATACCAAATTTGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GTACTATTAGCAACTGCAACATCTTCTTCAACTTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATAATGTATGCTTTGGTATTGCACCTATCCTATTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACTTTTTCTATCTCAGTCCAATACACAGTAATAAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTTCTTCATCGCAATGAGGACAATCAAATTTTAC
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAATCACTTCAACTTCCTCACTGTTTACAGTTACAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCTTTTTCTGTCAAGTTCTTTTTTTATTTTTTCACA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CAAACTGGCTAGAAGAAACGAAACGGATGTAATAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAGAAGTGATTCTTCATCCTGATAATTCCACTTAGT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATCTATTGTTACTGGTGTAGCTTTACCTGCTAGC
ATTTAAATACATCCTATGTTAAGGTTCAAC	TATTCTTTAAAATGTCTTTTGTGTTTAATACATTAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	AAACAAAGGTTAATAGCTTAGCTTTTGTTTTGAGG
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTACCTGTTACACTAAATTCATCAACCAAGATTTT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TTACTTTTTCTCTGCTGTTAGACGGTATATCAACGCA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CAGTTTGCCTTTAATTCTTGTTTCTTGCCATTCACT
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACTAGATGCTCTCTACAAGATATTGAGTTCACATAT
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGTAAGGAGCATAAGAGCATAGATAAAGATGACTG
ATTTAAATACATCCTATGTTAAGGTTCAAC	CCAACTATACCATCTACAGGAAGATGCAATATAGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GCTGACTGGCATTTAATTTTTTAGCAATTTCGACCTG
ATTTAAATACATCCTATGTTAAGGTTCAAC	CTGTGGTACTTACCTTTAAAGCAATGCTGTTACTCAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	GGAGTAAGACCACCAGTAATTGCAATCCCTGTCCA
ATTTAAATACATCCTATGTTAAGGTTCAAC	TAGAGCAAGGTAATGTAATTTAGATACTTAAAATT
ATTTAAATACATCCTATGTTAAGGTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013018.1\|WP_003442565.1\|2838948_2839839_-\|DUF2156-domain-containing-protein	unknown	unknown	gnl\|CDD\|227203
NZ_CP013018.1\|WP_003442556.1\|2836088_2836871_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NZ_CP013018.1\|WP_034829953.1\|2842954_2844082_-\|rod-shape-determining-protein-RodA	unknown	unknown	gnl\|CDD\|274033
NZ_CP013018.1\|WP_003442547.1\|2825997_2827734_-\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	gnl\|CDD\|188234
NZ_CP013018.1\|WP_003442554.1\|2835356_2835905_-\|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl\|CDD\|394878
NZ_CP013018.1\|WP_003442542.1\|2819817_2820819_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP013018.1\|WP_003442546.1\|2825031_2825976_-\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP013018.1\|WP_003442574.1\|2840029_2840863_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293817
NZ_CP013018.1\|WP_003442544.1\|2821639_2824267_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|350688
NZ_CP013018.1\|WP_003442558.1\|2836986_2837358_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319900
NZ_CP013018.1\|WP_003442552.1\|2831433_2832591_-\|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225420
NZ_CP013018.1\|WP_003442563.1\|2838466_2838730_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_003442545.1\|2824290_2825028_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP013018.1\|WP_051803910.1\|2829030_2830359_+\|transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP013018.1\|WP_003442541.1\|2819528_2819816_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP013018.1\|WP_003442578.1\|2841715_2842819_-\|rod-shape-determining-protein-RodA	unknown	unknown	gnl\|CDD\|274033
NZ_CP013018.1\|WP_003442561.1\|2837613_2838354_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|225130
NZ_CP013018.1\|WP_003442548.1\|2827753_2828461_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273848
NZ_CP013018.1\|WP_003442575.1\|2840940_2841684_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235506
NZ_CP013018.1\|WP_003442543.1\|2821008_2821503_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863

Protein	Function_ID	Function_description	E-value
NZ_CP013018.1\|WP_003442565.1\|2838948_2839839_-\|DUF2156-domain-containing-protein	gnl\|CDD\|227203	COG4866, COG4866, Uncharacterized conserved protein [Function unknown].	1.8147e-52
NZ_CP013018.1\|WP_003442556.1\|2836088_2836871_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	7.36395e-40
NZ_CP013018.1\|WP_034829953.1\|2842954_2844082_-\|rod-shape-determining-protein-RodA	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	1.43732e-116
NZ_CP013018.1\|WP_003442547.1\|2825997_2827734_-\|hypothetical-protein	gnl\|CDD\|188234	TIGR02591, cas_Csh1, CRISPR-associated protein Cas8b/Csh1, subtype I-B/HMARI. This domain is found in the C-terminal 2/3 of a family of CRISPR associated proteins of the Hmari subtype. Except for the two sequences from halophilic archaea this domain contains a pair of CXXC motifs.	1.64342e-15
NZ_CP013018.1\|WP_003442554.1\|2835356_2835905_-\|O-acetyl-ADP-ribose-deacetylase	gnl\|CDD\|394878	cd02908, Macro_OAADPr_deacetylase, macrodomain, O-acetyl-ADP-ribose (OAADPr) family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. This family includes eukaryotic macrodomain proteins such as human MacroD1 and MacroD2, and bacterial proteins such as Escherichia coli YmdB; these have been shown to be O-acetyl-ADP-ribose (OAADPr) deacetylases that efficiently catalyze the hydrolysis of OAADPr to produce ADP-ribose and free acetate. OAADPr is a sirtuin reaction product generated from the NAD+-dependent protein deacetylation reactions and has been implicated as a signaling molecule. By acting on mono-ADP-ribosylated substrates, OAADPr deacteylases may reverse cellular ADP-ribosylation.	1.40291e-92
NZ_CP013018.1\|WP_003442542.1\|2819817_2820819_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.03629e-143
NZ_CP013018.1\|WP_003442546.1\|2825031_2825976_-\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.07899e-48
NZ_CP013018.1\|WP_003442574.1\|2840029_2840863_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293817	cd07731, ComA-like_MBL-fold, Competence protein ComA, ComEC and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes proteins required for natural transformation competence including Neisseria gonorrhoeae ComA, Pseudomonas stutzeri ComA, Bacillus subtilis ComEC (also known as ComE operon protein 3) and Haemophilus influenza ORF2 encoded by the rec-2 gene, as well as Escherichia coli YcaI which does not mediate spontaneous plasmid transformation on nutrient-containing agar plates. It also includes the phosphorylcholine esterase (Pce) domain of choline-binding protein e from streptococcus pneumonia. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. .	1.18683e-11
NZ_CP013018.1\|WP_003442544.1\|2821639_2824267_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.65621e-25
NZ_CP013018.1\|WP_003442558.1\|2836986_2837358_-\|VOC-family-protein	gnl\|CDD\|319900	cd07233, GlxI_Zn, Glyoxalase I that uses Zn(++) as cofactor. This family includes eukaryotic glyoxalase I that prefers the divalent cation zinc as cofactor. Glyoxalase I (also known as lactoylglutathione lyase; EC 4.4.1.5) is part of the glyoxalase system, a two-step system for detoxifying methylglyoxal, a side product of glycolysis. This system is responsible for the conversion of reactive, acyclic alpha-oxoaldehydes into the corresponding alpha-hydroxyacids and involves 2 enzymes, glyoxalase I and II. Glyoxalase I catalyses an intramolecular redox reaction of the hemithioacetal (formed from methylglyoxal and glutathione) to form the thioester, S-D-lactoylglutathione. This reaction involves the transfer of two hydrogen atoms from C1 to C2 of the methylglyoxal, and proceeds via an ene-diol intermediate. Glyoxalase I has a requirement for bound metal ions for catalysis. Eukaryotic glyoxalase I prefers the divalent cation zinc as cofactor, whereas Escherichia coil and other prokaryotic glyoxalase I uses nickel. However, eukaryotic Trypanosomatid parasites also use nickel as a cofactor, which could possibly be explained by acquiring their GLOI gene by horizontal gene transfer. Human glyoxalase I is a two-domain enzyme and it has the structure of a domain-swapped dimer with two active sites located at the dimer interface. In yeast, in various plants, insects and Plasmodia, glyoxalase I is four-domain, possibly the result of a further gene duplication and an additional gene fusing event.	6.72904e-23
NZ_CP013018.1\|WP_003442552.1\|2831433_2832591_-\|putative-DNA-binding-domain-containing-protein	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	8.39619e-76
NZ_CP013018.1\|WP_003442545.1\|2824290_2825028_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	9.4005e-47
NZ_CP013018.1\|WP_051803910.1\|2829030_2830359_+\|transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.69791e-14
NZ_CP013018.1\|WP_003442541.1\|2819528_2819816_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.13046e-24
NZ_CP013018.1\|WP_003442578.1\|2841715_2842819_-\|rod-shape-determining-protein-RodA	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	2.81759e-110
NZ_CP013018.1\|WP_003442561.1\|2837613_2838354_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	3.29313e-14
NZ_CP013018.1\|WP_003442548.1\|2827753_2828461_-\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.72371e-05
NZ_CP013018.1\|WP_003442575.1\|2840940_2841684_-\|SDR-family-oxidoreductase	gnl\|CDD\|235506	PRK05565, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	2.38473e-117
NZ_CP013018.1\|WP_003442543.1\|2821008_2821503_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	8.46336e-54

>NZ_CP013018.1|WP_003442552.1|2831433_2832591_-|putative-DNA-binding-domain-containing-protein
MDRTELLNVIKNGENSYIEFKEEAIKAKDLAEEFVAFANAEGGTVLIGIADDGGIKGVTDSNIEEKIMNICRNNCIPNIIPLYEEIEFNQLKVVVVAISKGLNKPYYTVDNKYYIRVGTTKRIASREELMRLFEANGSIHFDISPVYNTSIKDLHFDIIRDYFFKYNTFDLYEEDKKSVERILINADILKEVDGKVVCSVGGLLIFGKNPDNTLPQNGISFAHFRGNEITDELIDKKVINGRLQDIAEQTLVVLKNNMKNPSTINQLKREEREEYPVLVLREAIVNALVHRNYSISGSKIRVFMFDDRIEFHSPGKLPNTVTIEKMKIGVSYARNPFLVKYMENMRYIDQLGRGIPMIMKEMKDMGVKDPDLREVGEEFILTVYK
>NZ_CP013018.1|WP_051803910.1|2829030_2830359_+|transposase
MVSIDQKSLIQTIKVYLSEYRSIFKKRSFVIFVILIEAILEVQELRSIKFLYDNFIKKYWTKVLNSFYYFLSYTKFSVESLMIVTVRIALTLIPEDIKSSITIFLIVDDTLQPKFGNKFDCYSKLFDHAQHNGTSYLNGHCFVSLVINIPVLFNGKIKYISLPVGYKLYDKTKSKLEIAGNMIANVMPLLIDYQVIVLYDSWYTKKPFLEILKNFNNIDIIGAVRSDTCLYDLQPKPTGKRGRPRKKGEKLKIKNFNYEKVDNYYIATKKVITNLFDEPVFVTVTTTDIDKFSSVRLYISSIEPSELKAFKNYITDDLNIDKSKPHLIPFYTYKIRWNIEVIFYKHKFFWSFGKYMVRSQEAIEKYVNLLAVAYSFAVILPFINRNFLKYKFESPQVIKNAVSYQISKELILRTFVQKLQKHKIQEEVLKAINSLASLNDAS
>NZ_CP013018.1|WP_003442548.1|2827753_2828461_-|hypothetical-protein
MNIFQCDFKVYLLKNIFKKDIQECLSKLIDKSFYENPSMKNFHDENKIKKYSFNQLYPVEKNGIYKEGYIYNFQVRCIGEELKDHFIRHLTNEYTSNMKILTSISKKIIKRPIDRIYSISSLIVKIADTEKTQYWRNNHNEEDFFEYIRKSCIKKYEMLTGEVLDKELRLFNYERIDNVKPIATKFKDKKLLGDKVTLNIETSNEAQNISYMLIGTGVADMAPRGYGFINYQYVK
>NZ_CP013018.1|WP_003442547.1|2825997_2827734_-|hypothetical-protein
MINEICEVFNREYEKLEDNMITDDYTLALGDYARFTLEDTYDTLEFFKVDKNTDVEQDDYKYFAKLDLMSTLISMNKPIDSKKIIHSNNIYTFFIKKDNLDPKNGKLNDDIIDEYYNILKNPSLKYKNKRKSMELYLEMEEAYGKPNIELIDKINFWIKENIFSMEKQFSNEKTYLKLFYDTSLENYKGESEKYILPNIYNSTDYNVKINGKVYGLPDFNMGLNSKKPYLENKTRKSKLPILVARDKIIIQKKLFDYLMNHSAQGKNYLYIDKEIEGVSPKENNKNNFQGYFLRVTKGKEVQIEDSDSITRYNYNFINSIKVIPILEDGVGKDFKLLKGQLKNIGELKIAIDEVFFYKWLNGNLFTEAKKISINDSVLKRILIQLRYGFYTWFYKGDDSIVRSFWNKVTKEILYNSMSEGNINGAINQFNLRHTLLDYFENKNGGENMARIIENIRRDVDEKINIIKDEEYKVEIDNDKEYYFCIGQLMRYFYVINKSNSKNYSFLRPLLVANDDKFMKEQLKRLFVKYSYAITGSIRFNNMYYMVSAYESKEVVDQDTFIAGFLCPNLILKKKEENN
>NZ_CP013018.1|WP_003442546.1|2825031_2825976_-|type-I-CRISPR-associated-protein-Cas7
MNRVYGVIGIKAIMANWNADFSGYPKTTNDGSIFGSDKALKYSIKKYWEDRGERILYMKSYKVDKDKMRPRSLEERYNQLFNTTLKNEDSTTVIKNLFSATDVKAFGATFAEEGNNISLIGAVQIGQGFNIYKKAFPEEQQILSPFRSDKKPKKGDEAKEANQSTLGTKITTDEAHYLYPFYINPISYNNYVEMDATEGYTEEDYKKFKEAALIGATALNTNAKAGCENEFAIFIETEEDTYLPNLAQFITFDEEDGNEASSRTLKFEQLNSLLDGVRDKVKNIEIYYNNYSLNIKGDTLEGARKFNIFTRKEL
>NZ_CP013018.1|WP_003442545.1|2824290_2825028_-|type-I-B-CRISPR-associated-protein-Cas5
MQVIRFKLSGKTAFFKKPDVNTYYYFTYGTIHKIAVLGIMGSILGLGGYNKQSENSKNEVYPEFYEKLKESKIAIITCNDKGYITKKVQSFNNSVGYASLEQGGNLIVKEQWLQEPKWIIYVKIDEATEKFAEMLENKKAMFIPYLGKNDHFADITEPKRLNLKKSDNSNTVDSLFITKNFQVGNATINRKILSWKYQEYLPVSLDEELNQYQFEDFTATNKKVLSNSNVDLYRDDELDKVVYFF
>NZ_CP013018.1|WP_003442544.1|2821639_2824267_-|CRISPR-associated-helicase/endonuclease-Cas3
MYFNNIDIFKVKDHIDNLDNIYAHTNDKNPNEKEEKLTEHTKRTHDYFIMLVKQKNLENVFINLEKIFFQDKNIELINLWKEMTINCICMHDIGKINPGFQCDVMKNERYKHNNADDSKHSLLSSYFYISYFDEKIQNSLLSEEDKDYITYFMYINAYLISRHHGYLKDFREYKNSYEGHEGNSQEEINEEKENNFPDLKFNVLEKCICEVFLEDSFNEITYNRLKKNDKFNFNIYIYSKLLFSLLTASDYYATSEFMDGQKIADIGIITEELKGKFKNAFDNYAITKEIRNYGKNPVLDENYENINQLRSEITLESEKNYLKNKDKNIFYLEAPTGAGKTITSVNLASLMLNSDNRLNKLFYVFPFNTLVEQTEKGLMDIFQNNDEIKQNISVINSLTPIKTVDENEDYKDFKSKEDNKKIDYKRSLLNRIFLHYPFIITTHVNLFSYLFGTSREEGFPLIDICNSVIIIDEIQSYKNGIWKEIINFFNSYAEILNIKLVIMSATLPRLNKLVEGENDNFVYLINNRKHYFENHFFKDRVKFEILDLSKVDKDNKYEDAFKILSDNIEMESKSDDKILIEFIFKKSADRFFDYFKSNYDFKNTTGHEIKIITSDDNKIDRLEIINLAKEKNRKVIIVATQVIEAGVDIDMDLGYKNISILDSEEQFMGRINRSCLNAGRVKFFKLDSCGILYQSDVRKEKRFTLEDENIQGILRNKDFESYYKNIISEIEVRKKRKNDSGYLAFIKELNRLNFDKIKDYMKLIDEKVDQNKYTIFLSREIKDLHGNIIHGNEIWKEYENLLMDNKIDYAEKRVRLSEINSKLNYFIYKVKRVEQYNEVLGNIFYIENGEEYIVNGRFNNEKFIGETPDQANLIL
>NZ_CP013018.1|WP_003442543.1|2821008_2821503_-|CRISPR-associated-protein-Cas4
MKITGTIINYYFHCKRQCWLHANRINLEDNSEEVRIGKVLHELKAEGKKNTEISIDNIKIDKITEDYLVEIKKSDADSEAVKWQVLLYLKKLREKGIERKGKIEFIEKNKQDKKIIYIELTDKNEKNLNDFLYNIEQFLIEEEPPAVELKPKCKKCAYYEYCFI
>NZ_CP013018.1|WP_003442542.1|2819817_2820819_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MGKGTRFIMSQGEITRKDNSICFRRNSKNVYMPIEAIREIYFLNEVSLNTKFLDFVAKAGVVIHFFNYYGYYSGTFYPKEYLISGKMTIKQSEAFINNRIEIAKAFVKGIAANIYEVVYHYYKHDKKETKLFLDWIKKDFIDLMDKSSDIKQILFLEGQVWMQFYDNFKYFLPENFLMNKRVKRPPDNPMNAMVSFGNSILYARTISQIYHTHLNQSISFLHEPSEGRFSLSLDLSEVFKPAIVFKTIFDLVNNKRIQVSKHFDKKLNYCLLNEAGKKIFVEALETRFNNVFQHKKLKRKISYETAIKLDGYKLIKHLIEKREFTPFSLKEMM
>NZ_CP013018.1|WP_003442541.1|2819528_2819816_-|CRISPR-associated-endonuclease-Cas2
MPKEVNYNYAFVFYDVNEKRVNKVFKICKKYFKHHQKSVFRGNITPANLIKLRAEIKKIIDEREDFVSIIKLMSENSFREETLGVNANNSESLII
>NZ_CP013018.1|WP_003442554.1|2835356_2835905_-|O-acetyl-ADP-ribose-deacetylase
MNYKKYSSKIEIIKGDITKIQVEAIVNAANSRLAGGGGVDGAIHRAAGGEELHRECIKIIEEKGNCPPGKVAITSAGKLKAKYIIHTVGPIWRGGNNNEEETLSQCYWNTLKLAIENKIKTIAFPNISTGIYGFPKLPAAKIALNTVSKFVEENKDIEKVIFVCFDEENWGIYRGMLNSARK
>NZ_CP013018.1|WP_003442556.1|2836088_2836871_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNINSKNIIITGASSGIGARLLKKLLNYDVKIIAVARNIDMIPNNDKVIPFSCDISRQEEIDKLFEYAVNVFNHIDIFIANAGFAYCEEIAEANWQHTEEIYKTNVFSPIYSTEKMKEINVNKPYHMVITCSAVSTFPLPGYSLYCSTKAAMHMFAKTYRYEMRNRGRLTLVYPVATRTNFFTRAGGNDAPIPWPVQSVNIVADIIILGIKLNLKSIYPSVLFIIGSIINRIVPILFPICSKIFSINFYRWLKKNNMKPH
>NZ_CP013018.1|WP_003442558.1|2836986_2837358_-|VOC-family-protein
MKFKFDHYNFNVLDLERSLSFYREALGFEEVRRHNAEDGSFILVYLGDKETGFTLELTWLKDRKEAYNLGESEFHLAVKTDNFQDAHEHHKKMGCICYENEAMGIYFIMDPDGYWIEIVPNKK
>NZ_CP013018.1|WP_003442561.1|2837613_2838354_+|MBL-fold-metallo-hydrolase
MNNYRAKINYLYNSGFTVETENYLLIFDYYKDSVSKGIKSIENGAISELNLKIPKKIIVFSSHSHFDHFNPVIFTWKKIRPDINYVLSNDITNIDNKDTNINILSPYEDLYLDNIYIKAFSSNDLGVSFLVKVDNINIFHSGDLNWWNWWDENGEFNLSMEKSFKSEIKKLEGIDIDIAFCPVDPRLKEYYYIGGEYFIKELNPKLFIPMHFGSKFSITTKFKEKVKYTNTTIIEIQKRGEEIIYS
>NZ_CP013018.1|WP_003442563.1|2838466_2838730_+|hypothetical-protein
MDKSLEETKQLNQKSAANKGNASAANSNFSNVTAGSSLEETRQLNQQSAANSGAANSSFSNTTASNSNLEETRQLNQKSAANKGTSK
>NZ_CP013018.1|WP_003442565.1|2838948_2839839_-|DUF2156-domain-containing-protein
MLQFKKLDLEDKELFDKYLKPFNFKSCEYSFTTLFIWKEACNIEYAVYDGVLILKKMDFNGKTHFMQPIGYDKNQLKEIFQVLDNYKIKNNMDYLFKDLECEFVEDLREYCPVEREIIEDRDNFDYIYPSNSLISLAGKKLHGKKNHYNQFVKNYDYYVKNIREVPIENCIESINKWLMHKGDVIDEYLKYEAQGIEAILKNKDKLEYNGIVVYVKDDIVGLTIGEKVNEEMAIIHIEKADPEIRGLYAFVNKTFVEQCFSDVQVINREQDLGKEGLRKAKQSYKPFEFVKKYIIQ
>NZ_CP013018.1|WP_003442574.1|2840029_2840863_-|MBL-fold-metallo-hydrolase
MEILLLVFGSSFAVFFITMGMNSIIKRNSKTKFYFIGVIISFIIAFIGFWKIPINTENNLSNKNDVTMSKDQGSIITNLEAMDSQAVSSVIKNNPLNVSFINNGLNGAVLIQFDGKNILVDSGKTDNIKYIEDSLKGHSVKNIDSIILTTSDEDSIGAAADLIKNYNIKDIRYIEDSIKNGKSFKDIQSSAEVNNTIVKKIDSSYSINNAIISTSSITKGVKVDFKFPEDQYDSSIQAMSFVKDSFNNESNQNLRHSVTTSCDSLGNIVVSVAAYRN
>NZ_CP013018.1|WP_003442575.1|2840940_2841684_-|SDR-family-oxidoreductase
MGCLDGKVVLVTGSSRGIGRHIAIEMAKEGASIAINYLKDEVGAKETLMILNREGVYAKEYRVDVRDFEAVTAMMKDIIENFGKIDVLINNAGVSKIGLFMDHCESDYNEVFDANFKSVFNCTNAVIKYMLEKKKGSIINISSIWGNVGASCEVLYSASKGAINSFTKALGKELAPSNIRVNAISPGVIDTSMNSVFSDEDIKNIKEEIPMMRFGRCDEIGKLAVFLASDNSSYITSQIITIDGGML
>NZ_CP013018.1|WP_003442578.1|2841715_2842819_-|rod-shape-determining-protein-RodA
MRKWIIDARLLRQLDITLIITALAISIFGVMNIYSASGISYLRTQIIFIIMAILICYVILLIDYNIMSNYSEIIYWIGVVLLLATDIQDMSVNGANSWLKIGPLPAIEPAEFFRMALALIIAKKISYMEGDINRPKNLIKILFYTAIPTIMLYKQPNLGMAIICICISFGILFISGLNLKIIFGAIALIIPASFIVWKAHILKAYQMARITSFLHPELTEQTTGYQLTNSKIGIGSGGILGKGFLHGTQVAGGYIPEARTDFIFSAVGEQWGLIGAIVLLALYVIILYRILVTARNSKDNLGRFICIGTFAGLTFSIYQNIAMTIGLAPISGITLPLMSAGGSSIIANFMALALVLNVGMRKKKINF
>NZ_CP013018.1|WP_034829953.1|2842954_2844082_-|rod-shape-determining-protein-RodA
MGVSNLKKWIIDIRLLRQIDVPLVVVTLAIAIFGVMNIYSATRISSGTFYLRTQVIYILVAIVICYIILLIDYNLISNYSDVFYWIGIVLLLATELQGTVINGSNSWLKLGPLPAIQPTEFLKIALIIIIAKKVSTMDGSINEPRNLIKIIVYTMIPLILILKQPEMGLAVICIFIVSSILFISGLNLKIILGTIALGIVVCFIAWEVLLQPYQIARITSFLNPEAHQQSTGYQLINSKIGIGSGGFWGKGYLNSTQISGGYVPFAHTDFIFSVVGEEWGLIGTGTLLISYGILLYRILKISKMSKDILGKLVCVGTFASLTFSIYQNIAMTIGLTPISGITLPFMSAGGSSIISNFMALALVLNISMRKKKINF

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Crispr_ID: NZ_CP013018_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013018_3

2992490-2992591

Orphan

Consensus_repeat	Method
ACTAATAATCAATGGACTTCAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP013018_3

>merge|NZ_CP013018|3|2992490-2992591|CRISPRCasFinder
ACTAATAATCAATGGACTTCAACACCTGAAGCTTCATCAAAAAAAGAAAATTATTCTCATAAAAAAGAAAAAACAGCTACTGATAATCAATGGACTTCAACA

>NZ_CP013018|3|3|2992490-2992591|CRISPRCasFinder
ACTAATAATCAATGGACTTCAACA	CCTGAAGCTTCATCAAAAAAAGAAAATTATTCTCATAAAAAAGAAAAAACAGCT
ACTGATAATCAATGGACTTCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013018.1\|WP_003442950.1\|3001656_3002490_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_003442918.1\|2985474_2985825_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP013018.1\|WP_003442956.1\|3004078_3005767_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|225971
NZ_CP013018.1\|WP_003442919.1\|2985790_2986111_-\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223932
NZ_CP013018.1\|WP_003442917.1\|2984281_2985103_-\|transketolase	unknown	unknown	gnl\|CDD\|238970
NZ_CP013018.1\|WP_003442942.1\|2997956_2998661_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP013018.1\|WP_003442924.1\|2988120_2989620_-\|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl\|CDD\|223141
NZ_CP013018.1\|WP_003442940.1\|2994603_2997954_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|223650
NZ_CP013018.1\|WP_003442954.1\|3002804_3003893_-\|iron-containing-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|341450
NZ_CP013018.1\|WP_003442931.1\|2990924_2991518_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_003442939.1\|2993319_2994438_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226400
NZ_CP013018.1\|WP_003442926.1\|2989620_2989995_-\|holo-ACP-synthase	unknown	unknown	gnl\|CDD\|234610
NZ_CP013018.1\|WP_003442943.1\|2998879_2999560_-\|ribose-5-phosphate-isomerase-A	unknown	unknown	gnl\|CDD\|238692
NZ_CP013018.1\|WP_003442933.1\|2991684_2992011_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|212140
NZ_CP013018.1\|WP_003442928.1\|2990375_2990729_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013018.1\|WP_003442945.1\|2999818_3000517_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NZ_CP013018.1\|WP_051035246.1\|3000680_3001709_-\|DNA-repair-photolyase	unknown	unknown	gnl\|CDD\|213890
NZ_CP013018.1\|WP_003442920.1\|2986231_2987392_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP013018.1\|WP_003442922.1\|2987449_2988049_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225390
NZ_CP013018.1\|WP_003442957.1\|3005829_3005955_-\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|275064

Protein	Function_ID	Function_description	E-value
NZ_CP013018.1\|WP_003442918.1\|2985474_2985825_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	3.73504e-43
NZ_CP013018.1\|WP_003442919.1\|2985790_2986111_-\|CopG-family-transcriptional-regulator	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.21887e-16
NZ_CP013018.1\|WP_003442917.1\|2984281_2985103_-\|transketolase	gnl\|CDD\|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	1.4979e-155
NZ_CP013018.1\|WP_003442942.1\|2997956_2998661_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.28314e-103
NZ_CP013018.1\|WP_003442956.1\|3004078_3005767_-\|diguanylate-cyclase	gnl\|CDD\|225971	COG3437, COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms].	1.56049e-62
NZ_CP013018.1\|WP_003442954.1\|3002804_3003893_-\|iron-containing-alcohol-dehydrogenase-family-protein	gnl\|CDD\|341450	cd08171, GlyDH-like, Glycerol dehydrogenase-like. This family contains glycerol dehydrogenase (GlyDH)-like proteins that have yet to be characterized, but show sequence homology with glycerol dehydrogenase. Glycerol dehydrogenases (GlyDH) is a key enzyme in the glycerol dissimilation pathway. In anaerobic conditions, many microorganisms utilize glycerol as a source of carbon through coupled oxidative and reductive pathways. One of the pathways involves the oxidation of glycerol to dihydroxyacetone with the reduction of NAD+ to NADH catalyzed by glycerol dehydrogenases. Dihydroxyacetone is then phosphorylated by dihydroxyacetone kinase and enters the glycolytic pathway for further degradation. The activity of GlyDH is zinc-dependent; the zinc ion plays a role in stabilizing an alkoxide intermediate at the active site.	0
NZ_CP013018.1\|WP_003442940.1\|2994603_2997954_-\|FtsX-like-permease-family-protein	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.17518e-11
NZ_CP013018.1\|WP_003442939.1\|2993319_2994438_+\|hypothetical-protein	gnl\|CDD\|226400	COG3883, COG3883, Uncharacterized protein conserved in bacteria [Function unknown].	2.87592e-39
NZ_CP013018.1\|WP_003442926.1\|2989620_2989995_-\|holo-ACP-synthase	gnl\|CDD\|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	7.81764e-51
NZ_CP013018.1\|WP_003442943.1\|2998879_2999560_-\|ribose-5-phosphate-isomerase-A	gnl\|CDD\|238692	cd01398, RPI_A, RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the conversion of phosphosugars into glycolysis intermediates, which are precursors for the synthesis of amino acids, vitamins, nucleotides, and cell wall components. In plants, RPI is part of the Calvin cycle as ribulose 5-phosphate is the carbon dioxide receptor in the first dark reaction of photosynthesis. There are two unrelated types of RPIs (A and B), which catalyze the same reaction, at least one type of RPI is present in an organism. RPI_A is more widely distributed than RPI_B in bacteria, eukaryotes, and archaea.	5.25178e-77
NZ_CP013018.1\|WP_003442933.1\|2991684_2992011_-\|hypothetical-protein	gnl\|CDD\|212140	cd11533, NTP-PPase_Af0060_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in uncharacterized protein from Archaeoglobus fulgidus (Af0060) and its bacterial homologs. This family includes an uncharacterized protein from Archaeoglobus fulgidus (Af0060) and its homologs from bacteria. Although its biological role remains unclear, Af0060 shows high sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, members in this family consist of a single MazG-like domain that contains a well conserved divalent ion-binding motif EXX[E/D].	0.000343188
NZ_CP013018.1\|WP_003442922.1\|2987449_2988049_-\|hypothetical-protein	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	5.34385e-06
NZ_CP013018.1\|WP_003442945.1\|2999818_3000517_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	1.63683e-49
NZ_CP013018.1\|WP_051035246.1\|3000680_3001709_-\|DNA-repair-photolyase	gnl\|CDD\|213890	TIGR04070, photo_TT_lyase, spore photoproduct lyase. DNA damage to bacterial spores from ultraviolet light accumulates in the form of 5-thyminyl-5,6-dihydrothymine, spore photoproduct. The damage is repaired by spore photoproduct lyase, a member of the radical SAM family of enzymes. The score of this model is set to restrict itself to spore-forming members of the Firmicutes, but additional homologs scoring below the trusted cutoff tend to occur in radioresistant organisms (e.g. Kineococcus radiotolerans) and may be functionally equivalent. A related family in the Mycobacterium lineage is described by family TIGR03886, and may or may not be equivalent in function. [DNA metabolism, DNA replication, recombination, and repair, Cellular processes, Sporulation and germination].	2.97681e-12
NZ_CP013018.1\|WP_003442920.1\|2986231_2987392_-\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP013018.1\|WP_003442924.1\|2988120_2989620_-\|NAD(P)H-hydrate-dehydratase	gnl\|CDD\|223141	COG0063, COG0063, Predicted sugar kinase [Carbohydrate transport and metabolism].	6.44033e-98
NZ_CP013018.1\|WP_003442957.1\|3005829_3005955_-\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|275064	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide. Members of this family of short peptides are precursors to thiolactone (unless Cys is replaced by Ser) cyclic autoinducer peptides, used in quorum-sensing systems in Gram-positive bacteria. The best characterized is the AgrD precursor, processed by the AgrB protein. Nearby proteins regularly encountered include a histidine kinase and a response regulator. This model is related to pfam05931 but is newer and currently broader in scope.	5.17343e-08

>NZ_CP013018.1|WP_003442933.1|2991684_2992011_-|hypothetical-protein
MKFPILSKNSSLNIDNDNYTLEQLSEKLEIEQKELNKAIMEDRNKGVIAEELFDTIQTCIGMLNKLSEDGIDMRYLALKHEKKLIKLGWRWRGYIEFKTMIMERNLKK
>NZ_CP013018.1|WP_003442931.1|2990924_2991518_-|hypothetical-protein
MNNKDYLGKLFRTFDDFVSLVASRELEYIIFDAKYTTYFNNKMRKVLNEINRSKRDLELFVMFNTRGEIAIIDSKIVGKYIANYYNIQMEKYYKDIKLNKIVWDVINGKSKTKTKRDFMVISYKIIYKVLNEIYMDIKCNKSILNEYKFRYGLENYSRKNISTIVISILILEDICNYIGIEEDILLDYLRKIYDDNI
>NZ_CP013018.1|WP_003442928.1|2990375_2990729_-|hypothetical-protein
MNIVDVFTKSITNDEIEHKYEYRITKSNIEIYNYGVNNDVQSYGIEIERKDILNGKTINLERDSVYNISPHRHKVQQLTKLLYDNEVSPINAIEILGDYVDEYIIDFDNVLKEISIG
>NZ_CP013018.1|WP_003442926.1|2989620_2989995_-|holo-ACP-synthase
MILGVGIDIVEINRIRDAIEKNSLFLKKVYTQNEIEYLKSRNLRPEYAAGRFAAKEAVSKALGTGFMQFSIRDIEIDRNVKGKPVVILKGKAKQIANKFGDYKIHLSISHSKENAIAYAILEVI
>NZ_CP013018.1|WP_003442924.1|2988120_2989620_-|NAD(P)H-hydrate-dehydratase
MKFVSSNIIKKIDNYCINELGISELVLMENAALKVIKNIDLKDNSYFTVICGTGNNGGDGFAVARHLISLKKNVQVFFVGNVEKMTDSCRANYSILKNMEVNIIFIQDLKDIEHLEVYLVYSDVIIDALLGTGINRNVEGIYDTVISTINENSQFTVSIDVPSGLNSDTGDVMGNCIDSNKTITFELYKSGFLNYNSEKYTGEIIVEKIGIPEFVISEFHDGGFVTDKDIFKKKVAVRDKYSHKGNYGRVLIFAGSEQYTGAAYISTEGAVRSGAGLVTLCCDEDILQTLRSKFNEAMTISSKNIEGVNKLLANSNCVAVGPGMGDNENTYKVLNFVLKNSKCPVVIDADGINVLSKDLSILENSKVPVLITPHPGEMSRLTGLPVDYIEKNRIKVAKEFAKKYNVIVLLKGYNTVITKGNSVIVNSTGNSAMASGGMGDCLTGIITSFIAQGQDVIDAAVTGAFLHGYCGEMLSKEMFNVSASDVLDAIPYAIKKLQN
>NZ_CP013018.1|WP_003442922.1|2987449_2988049_-|hypothetical-protein
MKKILLIFISIVLILIVTGCGKGKNDKSSIAYLKDLKSYTTDMSIEVKNNKQKLDYSGRQMYFLGLGYRLELNNQRVLIYKDDKIYITDLQNGNKYITDMNFDDVYKISFLGNFIDLLYTNERIKTSYKTVNGKKYELINTDMPDSNRNISHGILYVDVNKKIPQKLVVYDIKENEKFIVNYKNFVPNCSVDKSLFRVN
>NZ_CP013018.1|WP_003442920.1|2986231_2987392_-|alanine-racemase
MFKHLRPVWAEINVDNLEFNMRGIKKLSKSNEIFGVVKADAYGHGAVDVAAVLLENGVTRLSVAVVSEAVELRRAGIECPIMILGYTPLSLADEILKYDIEQTVFSYEYALKLSSIAEKRHIKVKIHIALDTGMGRIGFLPDGKSIEDVYKISRLPNIEIEGLFSHFSTADEENKEYTYRQFEIFNSFYKKLKEKGVSVRIRHIANSAAIMELPNTHLDGVRPGIILYGYYPSGEVDKSRLELKPVMTLKTNIVHIKTLKKGEYISYGRKFTCEKDSIIATLPVGYADGYTRLMFGKAKVIINDKFAPVVGRICMDQCMVDISHIPEAKVGDEVILMGQSLNCKFDADDIAKNIDTINYEVVCMVSKRVPRVYVKHGKVTKIRNYV
>NZ_CP013018.1|WP_003442919.1|2985790_2986111_-|CopG-family-transcriptional-regulator
MSSSKRLVVNLSDTLCSEFDKALKEDCKKRSEFIREAIILYIEEKKKINFMEEMKKGYMEMSELNLEICEMGFCSDIKELKEYEVKLSESDLPDDDGGETRRYILC
>NZ_CP013018.1|WP_003442918.1|2985474_2985825_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MVVKRGDIFYADLSPVVGSEQGGIRPVIIIQNDIGNKYSPTVIVAAITSQINKAKLPTHVEISSEEYGLNKDSVVLLEQIRTLDKKRLKEKIGHMTESDMEKVDKALLVSIALKCD
>NZ_CP013018.1|WP_003442917.1|2984281_2985103_-|transketolase
MQNDLKLLKENAVKIREDIITMLTESASGHTGGSLSAVEILTTLYFKEMNIDPENSKDENRDRFVLSKGHAAPALYSTLAERGYFNKSELKSLRKFGSILQGHPNMNYVPGIDMSTGSLGQGISAAVGMALAGKIDKKDYRVYALLGDGELEEGQVWEASMAAAHYKLDNLTAFVDHNGLQIDGKCEDVMSPEPVSNKFEAFNWHVINVNGHDFNELIQAIDEARKTKGRPTMIVCKTIKGKGVSFMEDQVSWHGVAPNKEQCDRALAEIRAE
>NZ_CP013018.1|WP_003442939.1|2993319_2994438_+|hypothetical-protein
MNKKAVSIIMMVALFTIIIGSNCFAAPTTDESAELKQTQNTKKQLEGKIKNLNTQIDDIIEKVDKNKKDMNKIDQDIQKTEEKLNTLEEHSKEQEILFKKRLRAIYISGGGNNYLDVILGSRSVSDLISSMDSISIVMKYDNKLVAQLQEQKNVINDKKKDLDDKNNQLTALKANNESILSNLNNDIKQQNKLLADAKEKENRLIAEQRAREEAEAQAAARAAAAAEQAKLAAAQAQAKKSVQVAQSENTSKKVASNPVSGSTSSPVPINRGAIPSGNSSNVLYMEATAYSDNGFTASGNKTHRDPNGYSTIAVDPRVIPLGSKVYVEGYGYAIASDTGGAIKGNIIDLYVHSDSEALSWGRRNVKVHIIGN
>NZ_CP013018.1|WP_003442940.1|2994603_2997954_-|FtsX-like-permease-family-protein
MKKTFFKNLFRDIKKSISRFLSIVIIIAIGVAFYAGVRATSPDMKISADYYFNNNNFMDFKLISTLGITEDDIEAIEKLKGISKAEGSYSIDGVIEKNNHSIVVNINSLPDKNSMNRINITEGRTIKSDKEVIVEERFLKEYKLNIGDIIVIKSGNKSNIKDNLKNDSFKIVGTAQSPLYISAQRQISSVGDGDVKGFIYILPEVFKNDVYTEMYVRCNNKESRYSLLKNEEYKNIMTEMEKQLKYAGIERNKIRYIQVLKNAEDKIDEAENKLVISRKEVENKVLQGRSKIEEARDKLNQGKVEFEKNESDFNKKISDAEKQISQGKVNIKIAKENIDLKDREIENGNIEIKKAKDKISHSENKLMESKLQAENRILKQMKAKLEKAKNNKDSMPFNPLYIREYNSIYNIYKNIKGKDFDSIYTNLNDSGFIDIFNGYFDIKVLKANFDKAALDISKGKQQIFTREQLLKEGEIKLKKGKSDVEVNKKRLSALEVKLDKKKKDGIARLSKEKINIKDSEKAINENIEKLNAEELKANSQLKLAEIEIQNNREKLKHIKNPQWYVLGRAFNIGYESFRQDSDRIDNIGKAFPLIFFLVAALVSLTTMTRMVQEKRIEIGTFKALGYSRLAIVSHYLIYSSLASIIGSIIGISFGFRLFPPLIMNAYGSLYTIPHYLTPFNANLALKASLIAIIFTTLASIGAALSELREVPALLMRPKPPKAGKTILAEKMSFLWKRLSFTKKVTARNIFRYKQRFFMTVIGIAACTGLIITGFALKEGIIGAMYKQFNEIYKYDMQINLNDYVDSEKKKNIYNSIIKKTNIKSALFIYSKNASVKEAGAGSEDVYIIVPESKDELNRYINLSMDDSTLTLGDEGVVITEKLSKLINKKVGDNFKINIEGKVVEGKISSITEQYIQHYIYISPSYYKKITGENIEFNSMYGTLYNSSNSSQENTLRMLKTIDEVNSVSFKNNIKVSLNKSIDSINSVVLVLIISAGILAFVVIYNLTNININERKRELATIKLLGFYDNELALYIYRENIILTIIGASAGILYGIFISKLIISSAEINAMMFIKSINFIYCIYSFMITIVFSFIVNLIMYNRFAKIDMIESLKNPE
>NZ_CP013018.1|WP_003442942.1|2997956_2998661_-|ABC-transporter-ATP-binding-protein
MENFIELKNVKKIYNMGEIIVKAVDDISFSIDKGEFVIILGASGAGKSTILNLLGGMDHVTEGSIYVDGKEISKYNKKMLTKYRREDIGFVFQFYNLVENLNALENVELAVEICKDAVNPKEVLKNVGLEARMSNFPSQLSGGEQQRVSIARALAKKPKLLLCDEPTGALDYSTGKSVLKLLLDTSQNYNMTVIVITHNSAIAPMANKIINVKNGKITSLKKNLKPVSIESIEW
>NZ_CP013018.1|WP_003442943.1|2998879_2999560_-|ribose-5-phosphate-isomerase-A
MNSDDLKRECAKEALKYIKNNSIIGLGGGSTISYLIDYIRENRNLNVKVVTPSFKTKMLCIDKGLEVLHTCVVDEVSIAFDGCDEVDEELNALKSGGGIHTKEKLIASMAEDYVLLVDKAKFSKTLTFKHPVVLEVLPDALKYVEKKLKKIGGVPILRTSAAKDGGTITENGNLLIDTDFNNVTNIQELENNLKNISGVIDTSLFTKVVTKVLITDEEGTKVISKN
>NZ_CP013018.1|WP_003442945.1|2999818_3000517_-|SDR-family-NAD(P)-dependent-oxidoreductase
MKSAIVTGASSGIGLEIAKVLLDMRYKVYGIARNFSKTDFQHENFIEIVCDITDINLLEKKIKDIRSGEKEIFILVNNAGIGYFGPHEEISTKKIHAMIATNLEAPIIFTHILLRDLKRNSGYIINISSITAKKSSPIGCAYSATKAGLSHFSESLFDETRKAGVKVVTIHPDMTKTDFYNNAKFKEGDLPESYITGECVSNVVEMILSQRPGTVLTDVTIRPQRHVIGKKK
>NZ_CP013018.1|WP_051035246.1|3000680_3001709_-|DNA-repair-photolyase
MKGRRFLSKLKIDLWNCKFSHIYVEEQALNYEISSKIIDNFNNSKVVKIDHYKDVFCRSHQNFVIQKNSPKLILAVKKNNFVYKGSQMCDSFGNSNFYYTSAVMNCIYNCEYCYLQGMYPSGNIVIFVNIEDSISEIEKMLKNHPVYLCVSYDTDLMALEGITGFLHKWIDTAVKHNNLKIEIRTKSASFELLKEIPCCDNVILAWTLSPKKVIEEFEIGTPFLQKRLENICQAIDRGWKVRLCFDPLLYINNWKIVYKEFIDTIFKNISGRRIYQVSIGVFRISKNYLKIINKLRTNSKILAYPFSVEDDICSYNEKHIEEMIVFVKNETMKYIYENKIYI
>NZ_CP013018.1|WP_003442950.1|3001656_3002490_-|hypothetical-protein
MIYFLTALYYEAKDIIFHYNMKKSMESTRFQVFKGKNEILIISGTGYIKSVAAVTYLLNCFGYNENDIFIDIGICGSTRYELEKGKIILCNKLIDNCSKKSFYPDMLFKHPFNEGTLESFAQVVEQDKLEKIEGDIVDQEGAFVYQAASIFAKPHNIHIIKIVSDILNPQSVTPEKIERLFVDSMQSIYIWLEKRVKINFYSEDIITEEEYNVLKLLSENIKLTSSMKMELNKLSTQYEIRNGNVIELLKEYTKFQCKSKNEGKKIFEQVKNRLMEL
>NZ_CP013018.1|WP_003442954.1|3002804_3003893_-|iron-containing-alcohol-dehydrogenase-family-protein
MSYSVFLPSYSIGTDAYDRIKELCPNYGKNIVVIGGKTAIEKVKKKIKSAVTDSTLEILDFIWYGGDSSFENVEMLKENPLIHKADIIFAVGGGRAIDTCKVLSHQINKPIFTFPTIASNCAACTSVCVMYDNKGVFKELYFRDKPAEHTFICTEIIAEAPKVFLWAGIGDALSKKYECTFSSRNDKLEHFNALGVQISKICTEPLLENGKKALEDCEANIASYELEQVTLDIIISTGLVSNLVINDYNSCLAHSIYYGMTELKQIEKNHLHGEVVSYGVLVLLLCDKQFDELNKVYNFCKSIGLPTKLSDLEVTKDELKIVISKVMQTGDIVHVPYEITYDMIEDSILKLEEYSNEPVKAV
>NZ_CP013018.1|WP_003442956.1|3004078_3005767_-|diguanylate-cyclase
MSEVDNKKKQINDIVSVVKLSSLLFSGMAFFKFVQKHFNISFSNFNYSLTIQFVIVSVLILTLIYSIWAFSTTKKFNKKYIIRIQIIENYIFVLIFLCIILLTGAHRSDFKFLFLFIIITTAIQSGMNQGLIIAFTSSIIVLTIDLIYAQGLMENIYFEKDLILAAVFILTAWPLGFYVKTERNHIEKLQNLANEDGLTGVYNHRFFHEALREKLISYKKENRPISLIFIDIDHFKHYNDLYGHQKGDQVLKIIGSLLKEIIVENGIAARYGGEEFAIILPDTLEQDAIKIAENIRYRIQETYFEGEENQPKGKITASMGVSTFPDKAENEVELIKCADDALYRAKFFNKNRVETYHSILDELKKEIEHKDIDLVTSIKTLISVINAKDRYTYGHVERVVFYSRLLAEKLGLSEEDKKKLVYGAYMHDIGKINIGEEVLNKKMPLNNEEWEVLKQHPANGVEIINPVKSLSYIAPLILHHHERYDGKGYPDNLKGENIPYLARILTVVDSFDAMTSNRPYSKIKSHSEAIEELKKCRGSQFDPDIADAFIEVIEENKDNITY
>NZ_CP013018.1|WP_003442957.1|3005829_3005955_-|cyclic-lactone-autoinducer-peptide
MKKKLLIVVAAVTTVVASVIASSACVFFFYQPEEPKCLQKR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP013018_2	2.14\|2833555\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2833555-2833590	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	35128-35163	2	0.944
NZ_CP013018_2	2.14\|2833555\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2833555-2833590	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	86837-86872	2	0.944
NZ_CP013018_2	2.14\|2833555\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2833555-2833590	36	LN681537	Clostridium phage phiCD211, complete genome	95699-95734	2	0.944
NZ_CP013018_1	1.7\|700398\|34\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	700398-700431	34	MN693625	Marine virus AFVG_250M334, complete genome	21803-21836	7	0.794
NZ_CP013018_2	2.14\|2833555\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2833555-2833590	36	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	58184-58219	7	0.806
NZ_CP013018_2	2.14\|2833555\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2833555-2833590	36	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	69182-69217	7	0.806
NZ_CP013018_2	2.14\|2833555\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2833555-2833590	36	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	209310-209345	7	0.806
NZ_CP013018_2	2.14\|2833555\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2833555-2833590	36	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	216497-216532	7	0.806
NZ_CP013018_2	2.26\|2834344\|36\|NZ_CP013018\|PILER-CR,CRISPRCasFinder,CRT	2834344-2834379	36	NC_010371	Finegoldia magna ATCC 29328 plasmid pFMC, complete sequence	52485-52520	8	0.778

1. spacer 2.14|2833555|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.944

acatatgagtatggtctttatcacattctattgcaa	CRISPR spacer
acatatgtgtatggtctttatcgcattctattgcaa	Protospacer
******* **************.*************

2. spacer 2.14|2833555|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 2, identity: 0.944

acatatgagtatggtctttatcacattctattgcaa	CRISPR spacer
acatatgtgtatggtctttatcgcattctattgcaa	Protospacer
******* **************.*************

3. spacer 2.14|2833555|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 2, identity: 0.944

acatatgagtatggtctttatcacattctattgcaa	CRISPR spacer
acatatgtgtatggtctttatcgcattctattgcaa	Protospacer
******* **************.*************

4. spacer 1.7|700398|34|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to MN693625 (Marine virus AFVG_250M334, complete genome) position: , mismatch: 7, identity: 0.794

acagcagttgcaaataatgcaactg-ctacagtac	CRISPR spacer
acagcagttgcaaatactgcacctgattctaata-	Protospacer
**************** **** *** .* .*.**

5. spacer 2.14|2833555|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.806

acatatgagtatggtctttatcacattctattgcaa	CRISPR spacer
acaagtggacatggtctttgtcacattccattgcaa	Protospacer
*** .**...*********.********.*******

6. spacer 2.14|2833555|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.806

acatatgagtatggtctttatcacattctattgcaa	CRISPR spacer
acaagtggacatggtctttgtcacattccattgcaa	Protospacer
*** .**...*********.********.*******

7. spacer 2.14|2833555|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.806

acatatgagtatggtctttatcacattctattgcaa	CRISPR spacer
acaagtggacatggtctttgtcacattccattgcaa	Protospacer
*** .**...*********.********.*******

8. spacer 2.14|2833555|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.806

acatatgagtatggtctttatcacattctattgcaa	CRISPR spacer
acaagtggacatggtctttgtcacattccattgcaa	Protospacer
*** .**...*********.********.*******

9. spacer 2.26|2834344|36|NZ_CP013018|PILER-CR,CRISPRCasFinder,CRT matches to NC_010371 (Finegoldia magna ATCC 29328 plasmid pFMC, complete sequence) position: , mismatch: 8, identity: 0.778

tattctttaaaatgtcttttgtgtttaatacattat	CRISPR spacer
tttttattaaaatgtgatttgtgtttaatacacttg	Protospacer
* **. *********  ***************.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

201572 : 272277

Pandoravirus(20.0%)

tRNA,protease,transposase,coat

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003440504.1\|201572_202514_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003440507.1\|202942_206047_+\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	4.8e-184	35.3
WP_003440509.1\|206279_207278_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_003440511.1\|207364_207949_+	hypothetical protein	NA	NA	NA	NA
WP_003440514.1\|208040_208445_-	hypothetical protein	NA	NA	NA	NA
WP_003440516.1\|208720_209650_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003440519.1\|209764_210046_-	hypothetical protein	NA	NA	NA	NA
WP_003440522.1\|210395_210581_+	hypothetical protein	NA	NA	NA	NA
WP_087946533.1\|210917_211064_-	hypothetical protein	NA	NA	NA	NA
WP_155760344.1\|211161_211335_-	hypothetical protein	NA	NA	NA	NA
WP_003440545.1\|213829_215353_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_003440548.1\|215432_215627_+	hypothetical protein	NA	NA	NA	NA
WP_158380935.1\|217271_217916_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_003440556.1\|218624_219383_-	response regulator transcription factor	NA	NA	NA	NA
WP_003440571.1\|219560_223613_+	AAA family ATPase	NA	NA	NA	NA
WP_003440573.1\|223704_224277_+	hypothetical protein	NA	NA	NA	NA
WP_003440576.1\|224483_226478_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.4e-05	23.0
WP_003440580.1\|226501_227725_+	peptidase T	NA	NA	NA	NA
WP_003440583.1\|227729_228092_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_003440585.1\|228588_230778_+	DNA topoisomerase III	A0A1V0SCS0	Indivirus	1.1e-25	26.6
WP_003440587.1\|230959_231643_+	response regulator transcription factor	NA	NA	NA	NA
WP_144311755.1\|231639_233052_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_003440593.1\|233294_233858_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	3.3e-35	44.9
WP_034830481.1\|233905_234382_+	HD domain-containing protein	NA	NA	NA	NA
WP_003440599.1\|234451_235261_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	9.4e-23	31.6
WP_003440602.1\|235262_236090_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	S4VNV0	Pandoravirus	1.4e-13	36.2
WP_087946534.1\|236086_236503_-	YibE/F family protein	NA	NA	NA	NA
WP_003440606.1\|236472_237210_-	class B sortase	NA	NA	NA	NA
WP_003440607.1\|237482_238748_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_174548957.1\|238816_239506_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	5.7e-37	40.8
WP_003440617.1\|239502_240699_+	ABC transporter permease	NA	NA	NA	NA
WP_034830476.1\|240721_241696_+	glycosyltransferase family 2 protein	M1FQW5	Enterobacteria_phage	2.8e-50	41.3
WP_003440623.1\|241865_242642_+	hypothetical protein	NA	NA	NA	NA
WP_003440625.1\|242871_243780_+	quinolinate synthase NadA	NA	NA	NA	NA
WP_003440628.1\|243784_245086_+	L-aspartate oxidase	NA	NA	NA	NA
WP_003440630.1\|245066_245903_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_003440633.1\|246494_247874_+	radical SAM protein	NA	NA	NA	NA
WP_003440637.1\|248189_249455_+	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003440640.1\|249709_250852_-	glycosyltransferase family 4 protein	A0A1X9SKE5	Sulfolobus_islandicus_rod-shaped_virus	4.3e-05	26.8
WP_003440641.1\|251007_252018_+\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_003440642.1\|252026_252239_+	hypothetical protein	NA	NA	NA	NA
WP_003440643.1\|252245_253004_+	hypothetical protein	NA	NA	NA	NA
WP_003440644.1\|253146_254175_+\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_034830471.1\|255705_256833_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_003440649.1\|257016_258021_+\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_003440652.1\|258135_259116_+	sporulation peptidase YabG	NA	NA	NA	NA
WP_003440655.1\|259361_259598_+	hypothetical protein	NA	NA	NA	NA
WP_003440657.1\|260108_261671_+	DUF3794 domain-containing protein	NA	NA	NA	NA
WP_003440660.1\|261806_262649_+	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_003440664.1\|262766_263651_-	HDOD domain-containing protein	NA	NA	NA	NA
WP_003440666.1\|264165_264579_-	hypothetical protein	NA	NA	NA	NA
WP_003440668.1\|264729_265845_+	stage II sporulation protein R	NA	NA	NA	NA
WP_003440673.1\|265873_267037_-	glycosyltransferase	NA	NA	NA	NA
WP_003440676.1\|267333_268707_+	germination protein YpeB	NA	NA	NA	NA
WP_003440679.1\|268898_269930_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_003440682.1\|270124_270541_+	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_034830312.1\|270648_272277_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	4.3e-51	30.6

DBSCAN-SWA_2

986045 : 1022208

Streptococcus_phage(50.0%)

transposase,integrase

attL 995670:995691|attR 1019931:1019952

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034829662.1\|986045_987305_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_143756607.1\|988492_989425_+	DUF4351 domain-containing protein	NA	NA	NA	NA
WP_003448163.1\|989601_990936_+	chloride channel protein	NA	NA	NA	NA
WP_003448166.1\|991424_991994_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_081353594.1\|992023_992824_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_003441125.1\|992868_993198_-\|transposase	transposase	NA	NA	NA	NA
WP_003448167.1\|993429_994719_+	MFS transporter	NA	NA	NA	NA
WP_003448168.1\|994906_995398_-	hypothetical protein	NA	NA	NA	NA
995670:995691	attL	NA	NA	NA	NA
WP_003448169.1\|995979_996714_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	6.2e-90	62.3
WP_003448170.1\|996943_997123_+	hypothetical protein	NA	NA	NA	NA
WP_003448171.1\|997162_997681_+	signal peptidase I	NA	NA	NA	NA
WP_003448173.1\|997709_997856_+	hypothetical protein	NA	NA	NA	NA
WP_003448174.1\|997902_998562_+	GyrI-like domain-containing protein	NA	NA	NA	NA
WP_003448176.1\|998657_999041_+	VOC family protein	NA	NA	NA	NA
WP_003448180.1\|999368_999833_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_051035279.1\|1000366_1001038_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_034829492.1\|1001133_1001628_+	hypothetical protein	NA	NA	NA	NA
WP_003448185.1\|1001664_1002231_+	flavodoxin family protein	NA	NA	NA	NA
WP_003448186.1\|1002262_1002445_+	hypothetical protein	NA	NA	NA	NA
WP_003448187.1\|1002655_1002871_+	hypothetical protein	NA	NA	NA	NA
WP_155760355.1\|1003073_1003250_+	hypothetical protein	NA	NA	NA	NA
WP_152414189.1\|1003392_1003752_+	hypothetical protein	NA	NA	NA	NA
WP_003448189.1\|1003860_1004328_+	VOC family protein	NA	NA	NA	NA
WP_003448191.1\|1005047_1005458_+	cytidine deaminase	NA	NA	NA	NA
WP_003448192.1\|1005496_1006453_+	hypothetical protein	NA	NA	NA	NA
WP_003448194.1\|1006509_1007265_+	3-oxoacyl-[acyl-carrier-protein] reductase	Q06VL0	Trichoplusia_ni_ascovirus	9.7e-22	33.1
WP_003448196.1\|1007360_1007681_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003448197.1\|1007785_1008322_+	flavin reductase family protein	NA	NA	NA	NA
WP_003448198.1\|1008970_1010563_+	AAA family ATPase	NA	NA	NA	NA
WP_003448199.1\|1010773_1011655_-	radical SAM protein	NA	NA	NA	NA
WP_003448200.1\|1011791_1012079_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003448201.1\|1012484_1013849_-	radical SAM protein	NA	NA	NA	NA
WP_003448202.1\|1013878_1014409_-	hypothetical protein	NA	NA	NA	NA
WP_003448280.1\|1014501_1014876_-	hypothetical protein	NA	NA	NA	NA
WP_034829696.1\|1014875_1016837_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_003448282.1\|1016829_1017957_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_003444851.1\|1018294_1019620_-	hypothetical protein	NA	NA	NA	NA
WP_003444848.1\|1020002_1020608_-	hypothetical protein	NA	NA	NA	NA
1019931:1019952	attR	NA	NA	NA	NA
WP_003444845.1\|1020981_1022208_+\|transposase	IS91 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

2062084 : 2070409

uncultured_Mediterranean_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003444245.1\|2062084_2062963_+	site-specific tyrosine recombinase XerD	A0A1B1IQT7	uncultured_Mediterranean_phage	6.0e-15	25.8
WP_003444249.1\|2063046_2064213_+	phosphopentomutase	NA	NA	NA	NA
WP_003444257.1\|2064225_2065041_+	purine-nucleoside phosphorylase	Q5YBA4	Grouper_iridovirus	1.8e-53	41.7
WP_003444259.1\|2065123_2065942_+	purine-nucleoside phosphorylase	Q5YBA4	Grouper_iridovirus	3.3e-60	47.5
WP_003444261.1\|2065960_2067262_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	5.9e-144	62.5
WP_003444263.1\|2067441_2068653_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	5.7e-32	32.0
WP_003444265.1\|2069070_2069829_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.4e-07	23.6
WP_034830758.1\|2069812_2070409_+	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	1.1e-20	37.3

DBSCAN-SWA_4

2086226 : 2136108

Paenibacillus_phage(22.22%)

bacteriocin,transposase,protease,coat,tRNA,integrase

attL 2114338:2114353|attR 2117509:2117524

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003444313.1\|2086226_2087279_+\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_003444314.1\|2087453_2088326_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_155760368.1\|2088392_2088539_-	hypothetical protein	NA	NA	NA	NA
WP_003444315.1\|2088997_2090329_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_003444316.1\|2090373_2093001_+	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	3.2e-56	27.5
WP_003444318.1\|2093076_2094969_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.1e-81	36.5
WP_034830709.1\|2095107_2096046_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_174548953.1\|2096146_2096398_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_003444325.1\|2097142_2098264_+	nitrogenase component 1	NA	NA	NA	NA
WP_003444327.1\|2098426_2099704_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_003444329.1\|2099865_2100477_-	transcriptional repressor LexA	A0A0N9RTK0	Paenibacillus_phage	1.9e-12	39.7
WP_003444331.1\|2100733_2101297_-\|protease	tesA-like protease	NA	NA	NA	NA
WP_003444332.1\|2101381_2101636_+	hypothetical protein	NA	NA	NA	NA
WP_003444335.1\|2102072_2102753_+	lipoyl(octanoyl) transferase LipB	NA	NA	NA	NA
WP_003444338.1\|2102807_2103683_+	lipoyl synthase	NA	NA	NA	NA
WP_003444339.1\|2103958_2105893_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_003444341.1\|2106175_2107159_+	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	E3SJ83	Synechococcus_phage	1.1e-09	25.7
WP_003444343.1\|2107160_2108135_+	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_003444345.1\|2108182_2109499_+	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_003444347.1\|2109512_2110904_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-53	30.9
WP_003444349.1\|2111165_2111741_+	arylesterase	NA	NA	NA	NA
WP_003444351.1\|2112064_2112475_+	hypothetical protein	NA	NA	NA	NA
WP_003444353.1\|2112592_2113582_-	tyrosine recombinase XerC	A0A2R2ZHE2	Clostridioides_phage	8.8e-15	26.3
2114338:2114353	attL	NA	NA	NA	NA
WP_003448320.1\|2114540_2115347_-	AAA family ATPase	NA	NA	NA	NA
WP_034829662.1\|2115362_2116622_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_155760369.1\|2119222_2119372_+	hypothetical protein	NA	NA	NA	NA
2117509:2117524	attR	NA	NA	NA	NA
WP_003442373.1\|2119812_2121033_-	ABC transporter permease	NA	NA	NA	NA
WP_003442371.1\|2121046_2122168_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_003442369.1\|2122412_2123249_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_003442366.1\|2123261_2124116_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_003442365.1\|2124153_2124666_-	hypothetical protein	NA	NA	NA	NA
WP_003442364.1\|2124686_2126048_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_034830050.1\|2126351_2126657_-	hypothetical protein	NA	NA	NA	NA
WP_003442362.1\|2126978_2128370_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_003442361.1\|2128481_2130326_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	4.3e-15	24.0
WP_143756567.1\|2130406_2130601_-\|bacteriocin	CA_C0660 family putative sactipeptide bacteriocin	NA	NA	NA	NA
WP_003442358.1\|2130691_2132053_-	insulinase family protein	A0A2K9LA15	Tupanvirus	1.3e-13	26.4
WP_034830048.1\|2132062_2133628_-	radical SAM protein	NA	NA	NA	NA
WP_087946539.1\|2133945_2134089_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_051035244.1\|2134090_2134705_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_076719024.1\|2134810_2135098_+\|transposase	transposase	NA	NA	NA	NA
WP_143756622.1\|2135187_2136108_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	9.3e-11	21.6

DBSCAN-SWA_5

2552951 : 2609852

Bacillus_phage(23.81%)

transposase,portal,capsid,terminase,head,tRNA,integrase,tail

attL 2599179:2599198|attR 2612511:2612530

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003441319.1\|2552951_2553689_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_003441315.1\|2553874_2554399_+	rubrerythrin	NA	NA	NA	NA
WP_003441311.1\|2554511_2555867_-	nitrogenase	NA	NA	NA	NA
WP_003441308.1\|2555903_2557454_-	hypothetical protein	NA	NA	NA	NA
WP_003441306.1\|2557969_2559721_-	DUF4153 domain-containing protein	NA	NA	NA	NA
WP_034829996.1\|2559992_2560136_-	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
WP_003441304.1\|2560554_2561337_+	hypothetical protein	U5Q0C0	Bacillus_phage	6.9e-39	65.3
WP_003441302.1\|2561482_2563267_-	diguanylate cyclase	G3MA91	Bacillus_virus	3.8e-16	41.9
WP_003441298.1\|2563647_2564229_-	hypothetical protein	NA	NA	NA	NA
WP_003441294.1\|2564724_2565561_-	ABC transporter permease	NA	NA	NA	NA
WP_003441290.1\|2565567_2566482_-	ATP-binding cassette domain-containing protein	A0A285PWH2	Cedratvirus	5.6e-16	27.3
WP_003441287.1\|2566783_2567905_-	DUF4885 family protein	NA	NA	NA	NA
WP_003441284.1\|2567950_2568838_-	hypothetical protein	NA	NA	NA	NA
WP_003440352.1\|2569611_2570907_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_003441281.1\|2571073_2571661_-	nitroreductase family protein	NA	NA	NA	NA
WP_003441277.1\|2572276_2573443_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_003441274.1\|2573512_2573878_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003441270.1\|2574254_2574773_-	VanZ family protein	NA	NA	NA	NA
WP_003441264.1\|2575307_2575628_-	thioredoxin family protein	NA	NA	NA	NA
WP_003441259.1\|2575827_2576097_-	hypothetical protein	NA	NA	NA	NA
WP_003444845.1\|2576112_2577339_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_003441250.1\|2578042_2579251_-	response regulator	NA	NA	NA	NA
WP_003441247.1\|2579264_2579711_-	response regulator	NA	NA	NA	NA
WP_003441244.1\|2579685_2583171_-	hypothetical protein	NA	NA	NA	NA
WP_003441241.1\|2583222_2583393_-	hypothetical protein	NA	NA	NA	NA
WP_003441238.1\|2583464_2585030_-	recombinase family protein	NA	NA	NA	NA
WP_155760376.1\|2585112_2585253_-	hypothetical protein	NA	NA	NA	NA
WP_003441235.1\|2585383_2586799_-	hypothetical protein	Q0H227	Geobacillus_phage	6.9e-21	27.5
WP_003441232.1\|2586815_2588444_-\|tail	phage tail protein	A0A0A7RUI9	Clostridium_phage	2.1e-50	38.7
WP_003441229.1\|2588443_2589145_-\|tail	phage tail family protein	A0A0A7RWN1	Clostridium_phage	6.2e-39	39.3
WP_003441227.1\|2589144_2591004_-	hypothetical protein	M4QNS0	Tetraselmis_viridis_virus	7.2e-18	24.6
WP_003441224.1\|2591003_2591324_-	hypothetical protein	NA	NA	NA	NA
WP_003441221.1\|2591341_2591677_-	hypothetical protein	A0A0U4KKN8	Bacillus_phage	1.2e-05	33.3
WP_003441218.1\|2591803_2592373_-	hypothetical protein	A0A0U4IS63	Bacillus_phage	8.8e-36	40.6
WP_152982474.1\|2592390_2592777_-	hypothetical protein	NA	NA	NA	NA
WP_003441214.1\|2592766_2593105_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_003441209.1\|2593094_2593397_-	hypothetical protein	NA	NA	NA	NA
WP_003441207.1\|2593401_2593698_-\|head,tail	phage head-tail connector protein	NA	NA	NA	NA
WP_003441204.1\|2593707_2593893_-	hypothetical protein	NA	NA	NA	NA
WP_003441203.1\|2593978_2595028_-\|capsid	major capsid protein	S5MNB6	Brevibacillus_phage	2.1e-144	72.2
WP_003441202.1\|2595049_2595433_-	hypothetical protein	A0A0K2CNR0	Brevibacillus_phage	3.5e-36	62.2
WP_003441201.1\|2595449_2596007_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_034829991.1\|2596289_2596745_-	hypothetical protein	A6N234	Microbacterium_phage	1.7e-18	48.6
WP_003441199.1\|2596827_2597244_-	hypothetical protein	NA	NA	NA	NA
WP_155760556.1\|2597570_2597912_-	hypothetical protein	NA	NA	NA	NA
WP_003441190.1\|2597874_2598774_-\|capsid	minor capsid protein	S5M601	Brevibacillus_phage	8.2e-20	30.0
WP_003441188.1\|2598760_2600038_-\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	5.6e-62	35.3
2599179:2599198	attL	NA	NA	NA	NA
WP_003441184.1\|2600099_2600519_-	protein-export chaperone SecB	NA	NA	NA	NA
WP_003441180.1\|2600515_2600983_-	hypothetical protein	NA	NA	NA	NA
WP_003441177.1\|2600988_2601408_-	hypothetical protein	NA	NA	NA	NA
WP_034829988.1\|2601480_2603031_-\|terminase	phage terminase large subunit	A0A0N7AEF1	Bacillus_phage	9.7e-77	35.6
WP_003441172.1\|2603200_2604250_+	AAA family ATPase	Q7M293	Enterobacteria_phage	1.6e-27	30.6
WP_003441170.1\|2604279_2605125_-\|integrase	tyrosine-type recombinase/integrase	A0A0E3M2X0	Bacillus_phage	3.5e-20	28.9
WP_003441168.1\|2605309_2606014_-	hypothetical protein	A0A2H4JAE2	uncultured_Caudovirales_phage	1.9e-24	47.9
WP_003441166.1\|2606066_2606729_-	hypothetical protein	NA	NA	NA	NA
WP_003441163.1\|2606851_2607274_-	gamma-glutamylcyclotransferase	G3MAQ5	Bacillus_virus	4.0e-17	35.6
WP_003441161.1\|2607344_2608253_-	amidoligase family protein	A0A2K9V489	Faecalibacterium_phage	6.9e-67	45.5
WP_003441158.1\|2608341_2608611_-	hypothetical protein	NA	NA	NA	NA
WP_003441156.1\|2608607_2609852_-	DNA modification methylase	E4ZFL4	Streptococcus_phage	1.8e-121	50.7
2612511:2612530	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2647488 : 2661861

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003447551.1\|2647488_2648991_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.5e-61	43.8
WP_003447550.1\|2649379_2649997_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-20	36.6
WP_003447549.1\|2649984_2650980_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	2.1e-64	45.1
WP_003447548.1\|2651000_2652410_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.0e-57	34.8
WP_003447546.1\|2652435_2653146_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	5.3e-46	43.7
WP_003447544.1\|2653145_2653625_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.9e-31	49.4
WP_003447542.1\|2654224_2657986_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.3e-34	24.1
WP_003447540.1\|2658198_2658723_+	tryptophan transporter	NA	NA	NA	NA
WP_003447538.1\|2659029_2659401_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	1.7e-11	32.7
WP_003447537.1\|2659575_2661861_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	7.5e-110	33.6

DBSCAN-SWA_7

2829030 : 2885341

Bacillus_phage(21.43%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_051803910.1\|2829030_2830359_+\|transposase	transposase	NA	NA	NA	NA
WP_003442552.1\|2831433_2832591_-	putative DNA binding domain-containing protein	A0A1B3AYT3	Gordonia_phage	3.0e-22	28.7
WP_003442554.1\|2835356_2835905_-	O-acetyl-ADP-ribose deacetylase	A0A0K1L687	Scale_drop_disease_virus	8.8e-33	45.2
WP_003442556.1\|2836088_2836871_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_003442558.1\|2836986_2837358_-	VOC family protein	NA	NA	NA	NA
WP_003442561.1\|2837613_2838354_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_003442563.1\|2838466_2838730_+	hypothetical protein	NA	NA	NA	NA
WP_003442565.1\|2838948_2839839_-	DUF2156 domain-containing protein	NA	NA	NA	NA
WP_003442574.1\|2840029_2840863_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_003442575.1\|2840940_2841684_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_003442578.1\|2841715_2842819_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_034829953.1\|2842954_2844082_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_003442592.1\|2844280_2844499_-	DUF3892 domain-containing protein	NA	NA	NA	NA
WP_003442595.1\|2844607_2845255_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_071167516.1\|2845527_2846208_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_003442599.1\|2846375_2847401_-	hypothetical protein	NA	NA	NA	NA
WP_003442602.1\|2847411_2848440_-	phosphodiester glycosidase family protein	A0A1P8CWN9	Bacillus_phage	1.2e-09	26.9
WP_003442605.1\|2848582_2849623_-	hypothetical protein	NA	NA	NA	NA
WP_003442608.1\|2849640_2850723_-	phosphodiester glycosidase family protein	A0A291LB83	Escherichia_phage	4.5e-12	37.2
WP_003442611.1\|2851044_2852421_-	PhoH family protein	A0A141HS37	Bacillus_phage	9.7e-121	48.0
WP_003442614.1\|2852894_2853323_+	transcriptional repressor	NA	NA	NA	NA
WP_003442617.1\|2853437_2854388_+	hypothetical protein	NA	NA	NA	NA
WP_003441259.1\|2854555_2854825_-	hypothetical protein	NA	NA	NA	NA
WP_003444845.1\|2854840_2856067_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_003442620.1\|2856390_2856975_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_003442623.1\|2856955_2859298_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	9.9e-174	43.6
WP_003442626.1\|2859421_2861098_-\|protease	ATP-dependent protease LonB	A0A167RA83	Powai_lake_megavirus	1.0e-15	33.1
WP_003442629.1\|2861244_2862549_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-140	58.4
WP_003442632.1\|2862568_2863153_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	4.8e-53	56.2
WP_003442635.1\|2863276_2864572_-	trigger factor	NA	NA	NA	NA
WP_003442639.1\|2864795_2865578_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_003442642.1\|2865601_2866393_-	hypothetical protein	NA	NA	NA	NA
WP_003442644.1\|2866795_2869984_-	carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit	NA	NA	NA	NA
WP_003442647.1\|2870093_2871179_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	1.5e-55	35.0
WP_003442650.1\|2871524_2873042_-	M1 family metallopeptidase	NA	NA	NA	NA
WP_003442654.1\|2873253_2873835_-	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	6.3e-05	31.0
WP_003442657.1\|2873980_2874880_-	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_003442660.1\|2874872_2875613_-	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
WP_003442668.1\|2875797_2876661_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_003442670.1\|2876672_2877860_-	dihydroorotase	NA	NA	NA	NA
WP_003442673.1\|2878075_2878498_-	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_003442675.1\|2878498_2879422_-	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.7e-52	39.7
WP_003442677.1\|2879894_2880500_+	DedA family protein	NA	NA	NA	NA
WP_003442679.1\|2880677_2881250_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_003442680.1\|2881292_2883032_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.4e-62	34.1
WP_003442685.1\|2883303_2883507_+	alpha/beta-type small acid-soluble spore protein	NA	NA	NA	NA
WP_034829948.1\|2883712_2885341_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	2.5e-51	30.6

DBSCAN-SWA_8

3683723 : 3786053

102

Clostridium_phage(47.37%)

transposase,portal,protease,capsid,terminase,head,tRNA,integrase,tail

attL 3732542:3732601|attR 3769206:3769281

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003444845.1\|3683723_3684950_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_051035266.1\|3685068_3685836_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	3.2e-20	37.1
WP_003446396.1\|3685981_3687052_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_003446394.1\|3687246_3687939_-	molecular chaperone TorD family protein	NA	NA	NA	NA
WP_003446392.1\|3687940_3688912_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_003446391.1\|3688915_3689497_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	7.1e-49	44.0
WP_003446387.1\|3689677_3692347_-	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	1.6e-82	28.2
WP_003446386.1\|3692659_3695044_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.1e-143	39.0
WP_003446383.1\|3695333_3695555_-	NifU family protein	NA	NA	NA	NA
WP_003446380.1\|3695740_3696157_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003446377.1\|3696434_3697070_-	flavodoxin family protein	NA	NA	NA	NA
WP_003446375.1\|3697314_3697656_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003446373.1\|3697796_3697964_-	hypothetical protein	NA	NA	NA	NA
WP_003446371.1\|3698127_3699636_-	glycoside hydrolase family 32 protein	NA	NA	NA	NA
WP_003446369.1\|3699660_3700509_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_003446368.1\|3700511_3701453_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_003446367.1\|3701688_3703005_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003446366.1\|3703119_3704097_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_003446365.1\|3704395_3705367_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_003446364.1\|3705470_3706325_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_003446363.1\|3706758_3707586_+	PHP domain-containing protein	NA	NA	NA	NA
WP_003446362.1\|3707682_3707877_-	hypothetical protein	NA	NA	NA	NA
WP_003446005.1\|3713745_3714222_+	NAD(P)H-dependent oxidoreductase subunit E	NA	NA	NA	NA
WP_003446003.1\|3714347_3715103_-	AAA family ATPase	NA	NA	NA	NA
WP_003446001.1\|3715099_3715846_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_003446000.1\|3715872_3716394_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_087946548.1\|3716396_3718274_-	anaerobic carbon-monoxide dehydrogenase catalytic subunit	NA	NA	NA	NA
WP_162838520.1\|3718329_3720186_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_003445997.1\|3720548_3721181_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_003445996.1\|3721549_3721723_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_003445995.1\|3722058_3722835_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_003445993.1\|3723599_3723890_-	hypothetical protein	NA	NA	NA	NA
WP_003445991.1\|3724235_3724667_+	LysE family transporter	NA	NA	NA	NA
WP_003445989.1\|3724673_3725072_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003445982.1\|3725068_3725482_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003445981.1\|3726874_3727420_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_034829853.1\|3727938_3728295_+	four-helix bundle copper-binding protein	NA	NA	NA	NA
WP_003445979.1\|3729030_3730062_-	Cfr family 23S rRNA (adenine(2503)-C(8))-methyltransferase	NA	NA	NA	NA
WP_003445978.1\|3730217_3731702_-	Lsa family ABC-F type ribosomal protection protein	A0A2K9L3Z8	Tupanvirus	1.1e-24	26.6
3732542:3732601	attL	NA	NA	NA	NA
WP_003445977.1\|3733243_3733453_-	hypothetical protein	NA	NA	NA	NA
WP_162838519.1\|3733468_3733615_-	hypothetical protein	NA	NA	NA	NA
WP_081387060.1\|3733626_3734046_-	peptidoglycan-binding protein	NA	NA	NA	NA
WP_003445973.1\|3734463_3734688_-	hypothetical protein	NA	NA	NA	NA
WP_076719123.1\|3734710_3736585_-\|tail	phage tail protein	H7BV46	unidentified_phage	3.0e-24	28.3
WP_003445971.1\|3736767_3737145_-	hypothetical protein	NA	NA	NA	NA
WP_003445969.1\|3737123_3737540_-	HEPN domain-containing protein	NA	NA	NA	NA
WP_003445967.1\|3737872_3738169_-	hypothetical protein	NA	NA	NA	NA
WP_003445965.1\|3738186_3740028_-	hypothetical protein	NA	NA	NA	NA
WP_003445964.1\|3740086_3740797_-\|tail	phage tail family protein	A0A286QN36	Streptococcus_phage	1.9e-19	29.1
WP_003445963.1\|3740797_3743362_-\|tail	phage tail tape measure protein	A0A1L2BYA6	Clostridium_phage	3.8e-70	45.4
WP_034830073.1\|3743583_3743883_-	hypothetical protein	A0A1L2BYA4	Clostridium_phage	4.7e-12	40.2
WP_003445960.1\|3743936_3744512_-\|tail	phi13 family phage major tail protein	A0A1L2BYA0	Clostridium_phage	2.2e-58	58.9
WP_003445958.1\|3744532_3744865_-	hypothetical protein	NA	NA	NA	NA
WP_003445955.1\|3744867_3745251_-	HK97 gp10 family phage protein	E2ELI9	Clostridium_phage	1.1e-16	38.8
WP_003445954.1\|3745250_3745610_-\|head	phage head closure protein	NA	NA	NA	NA
WP_003445953.1\|3745610_3745901_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_003445952.1\|3745947_3747042_-\|capsid	phage major capsid protein	I2E8V4	Clostridium_phage	2.3e-96	53.6
WP_003445951.1\|3747100_3747700_-\|head,protease	HK97 family phage prohead protease	D7PQ42	Enterococcus_phage	4.9e-29	40.9
WP_003445950.1\|3747704_3748922_-\|portal	phage portal protein	I2E8V3	Clostridium_phage	9.6e-80	41.5
WP_003445949.1\|3748922_3749126_-	hypothetical protein	NA	NA	NA	NA
WP_003445948.1\|3749142_3750828_-\|terminase	terminase large subunit	A0A0A7RUM0	Clostridium_phage	8.4e-167	52.0
WP_003445945.1\|3750827_3751286_-\|terminase	phage terminase small subunit P27 family	A0A0A7RUQ4	Clostridium_phage	4.3e-41	62.7
WP_003445944.1\|3751475_3751910_-	hypothetical protein	Q0SPJ9	Clostridium_phage	4.7e-13	36.6
WP_155760388.1\|3751912_3752077_-	hypothetical protein	NA	NA	NA	NA
WP_003445943.1\|3752182_3752452_-	hypothetical protein	NA	NA	NA	NA
WP_034830069.1\|3752463_3752802_-	hypothetical protein	NA	NA	NA	NA
WP_003445941.1\|3753079_3753301_-	hypothetical protein	NA	NA	NA	NA
WP_003445940.1\|3753380_3753695_-	hypothetical protein	NA	NA	NA	NA
WP_034830067.1\|3753696_3754149_-	hypothetical protein	NA	NA	NA	NA
WP_003445937.1\|3754148_3754409_-	hypothetical protein	NA	NA	NA	NA
WP_003445933.1\|3754543_3755056_-	hypothetical protein	NA	NA	NA	NA
WP_003445931.1\|3755149_3755899_-	hypothetical protein	NA	NA	NA	NA
WP_003445929.1\|3756424_3758584_-	hypothetical protein	NA	NA	NA	NA
WP_155760390.1\|3758609_3758777_-	hypothetical protein	NA	NA	NA	NA
WP_003445927.1\|3758863_3762151_-	hypothetical protein	NA	NA	NA	NA
WP_003445925.1\|3762656_3762857_-	hypothetical protein	NA	NA	NA	NA
WP_003445923.1\|3762876_3763599_-	hypothetical protein	A0A0K2FM38	Brevibacillus_phage	1.6e-10	28.0
WP_003445921.1\|3763672_3764014_-	hypothetical protein	NA	NA	NA	NA
WP_003445919.1\|3764164_3764392_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003445915.1\|3764465_3765341_-	hypothetical protein	NA	NA	NA	NA
WP_003445914.1\|3765344_3766478_-	hypothetical protein	NA	NA	NA	NA
WP_003445912.1\|3766571_3766808_-	hypothetical protein	NA	NA	NA	NA
WP_003445910.1\|3767450_3767702_-	hypothetical protein	NA	NA	NA	NA
WP_003445908.1\|3767717_3768032_-	hypothetical protein	NA	NA	NA	NA
WP_003445907.1\|3768034_3769048_-\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	8.1e-32	28.0
WP_003445904.1\|3769523_3769946_-	DUF2000 domain-containing protein	NA	NA	NA	NA
3769206:3769281	attR	NA	NA	NA	NA
WP_003445901.1\|3770017_3770842_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_003445899.1\|3771087_3771471_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_003445897.1\|3771484_3772387_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003445895.1\|3772576_3773839_+	HD domain-containing protein	NA	NA	NA	NA
WP_003445893.1\|3774059_3774518_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_003445892.1\|3774514_3775228_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_003445890.1\|3775220_3775670_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_003445888.1\|3775763_3776387_-	ECF transporter S component	NA	NA	NA	NA
WP_003445886.1\|3776683_3778840_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_003445883.1\|3779113_3779440_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003445881.1\|3779604_3780159_+	nitroreductase family protein	NA	NA	NA	NA
WP_143756631.1\|3780187_3781135_-	galactose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_003445878.1\|3781189_3782497_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_003445876.1\|3782520_3784008_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_003445875.1\|3784009_3784912_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_003445871.1\|3784976_3786053_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA

DBSCAN-SWA_9

4025420 : 4082710

Streptococcus_phage(18.75%)

tRNA,holin,transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158380946.1\|4025420_4025567_+\|transposase	transposase	NA	NA	NA	NA
WP_034830606.1\|4025677_4027231_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_003447816.1\|4027314_4027503_+	hypothetical protein	NA	NA	NA	NA
WP_034830604.1\|4027588_4028359_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	4.9e-37	38.1
WP_003447612.1\|4029974_4030652_-	YIP1 family protein	NA	NA	NA	NA
WP_003447614.1\|4030683_4031061_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003447615.1\|4031090_4032278_-	ABC transporter permease	NA	NA	NA	NA
WP_003447617.1\|4032274_4032961_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-34	37.8
WP_003447619.1\|4032938_4033991_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_155760402.1\|4034115_4034280_-	hypothetical protein	NA	NA	NA	NA
WP_003447621.1\|4034269_4034944_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.9e-13	29.4
WP_003447623.1\|4034960_4035461_-	stage II sporulation protein M	NA	NA	NA	NA
WP_003447630.1\|4037372_4037693_-	hypothetical protein	NA	NA	NA	NA
WP_003447632.1\|4038309_4039662_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_003447635.1\|4039855_4040377_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_003447637.1\|4040433_4041087_+	HAD family phosphatase	NA	NA	NA	NA
WP_003447638.1\|4041279_4041720_+	hypothetical protein	NA	NA	NA	NA
WP_003447640.1\|4041766_4043323_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	7.8e-50	27.6
WP_003447643.1\|4043443_4044154_-	2-phosphosulfolactate phosphatase family protein	NA	NA	NA	NA
WP_003447646.1\|4044278_4045229_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003447648.1\|4045240_4046350_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	Q6GZ03	Mycoplasma_phage	1.4e-21	31.8
WP_143756599.1\|4046444_4047374_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.7e-31	43.9
WP_003447653.1\|4047470_4048628_-	hypothetical protein	NA	NA	NA	NA
WP_003447655.1\|4048884_4049931_+	hypothetical protein	NA	NA	NA	NA
WP_003447656.1\|4050016_4050916_+	radical SAM protein	NA	NA	NA	NA
WP_003447659.1\|4051057_4052857_-	heme NO-binding domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.0e-05	28.3
WP_003447661.1\|4052876_4053551_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003447663.1\|4053556_4053943_-	DUF3783 domain-containing protein	NA	NA	NA	NA
WP_003447665.1\|4053998_4054514_-	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	3.5e-23	43.9
WP_003447666.1\|4054666_4055446_-	glutamate racemase	NA	NA	NA	NA
WP_003447667.1\|4055869_4057957_+	glutamine synthetase III	NA	NA	NA	NA
WP_003447668.1\|4058050_4058857_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.0e-37	37.6
WP_003447669.1\|4059027_4059828_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.2e-60	47.8
WP_003447670.1\|4059856_4061113_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-108	53.3
WP_034830663.1\|4061189_4061444_+	DUF4491 family protein	NA	NA	NA	NA
WP_003447672.1\|4061529_4062921_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.3e-83	36.0
WP_003447673.1\|4063298_4065140_+	asparagine synthase (glutamine-hydrolyzing)	R4TIC1	Phaeocystis_globosa_virus	2.9e-27	25.5
WP_003447684.1\|4065192_4065357_-	rubredoxin	NA	NA	NA	NA
WP_003447686.1\|4065569_4066106_-	peroxiredoxin	NA	NA	NA	NA
WP_003447688.1\|4066160_4066388_-	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_003447690.1\|4066389_4067316_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.6e-61	40.7
WP_003447691.1\|4067668_4067965_+\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
WP_003447692.1\|4067985_4068258_+\|coat	spore coat protein CotJB	NA	NA	NA	NA
WP_003447694.1\|4068288_4068861_+	manganese catalase family protein	NA	NA	NA	NA
WP_003447696.1\|4069064_4069604_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_143756635.1\|4069608_4070175_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_158380947.1\|4070285_4070447_-	hypothetical protein	NA	NA	NA	NA
WP_168170744.1\|4070604_4070760_-	hypothetical protein	NA	NA	NA	NA
WP_003447703.1\|4070918_4072307_-	Fe-only nitrogenase subunit beta	NA	NA	NA	NA
WP_003447705.1\|4072322_4072673_-	Fe-only nitrogenase subunit delta	NA	NA	NA	NA
WP_003447707.1\|4072688_4074266_-	nitrogenase iron-iron protein, alpha chain	NA	NA	NA	NA
WP_003440352.1\|4074674_4075970_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_003447709.1\|4076155_4076983_-	nitrogenase iron protein	NA	NA	NA	NA
WP_003447711.1\|4078072_4079830_-	ATP-dependent RNA helicase	A0A248SJQ0	Salicola_phage	2.5e-60	31.7
WP_003447713.1\|4080005_4081580_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_143756600.1\|4081579_4082710_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	2.6e-18	44.2

DBSCAN-SWA_10

4269572 : 4325917

Clostridium_phage(81.08%)

holin,transposase,protease,terminase,integrase

attL 4288800:4288817|attR 4335232:4335249

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_051035257.1\|4269572_4270028_+\|integrase	site-specific integrase	A0A0A8WF01	Clostridium_phage	1.5e-09	32.0
WP_158380949.1\|4270084_4270246_+	hypothetical protein	NA	NA	NA	NA
WP_003445019.1\|4270565_4271882_-	High affinity gluconate/L-idonate permease	NA	NA	NA	NA
WP_003445018.1\|4272292_4274011_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_003445017.1\|4274273_4275590_-	High affinity gluconate/L-idonate permease	NA	NA	NA	NA
WP_003445015.1\|4276009_4276687_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_003445014.1\|4276712_4277732_-	sugar kinase	NA	NA	NA	NA
WP_003445013.1\|4277750_4278395_-	bifunctional 2-keto-4-hydroxyglutarate aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase	NA	NA	NA	NA
WP_003445012.1\|4278637_4279402_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_003445011.1\|4279779_4280220_+	Hsp20/alpha crystallin family protein	A0A218MMV3	uncultured_virus	1.6e-05	31.1
WP_003445010.1\|4280852_4281350_-	hypothetical protein	NA	NA	NA	NA
WP_003445009.1\|4281404_4282388_-	N-acetylmuramoyl-L-alanine amidase	A0A0A7RUJ1	Clostridium_phage	2.0e-35	42.2
WP_003445002.1\|4282406_4282796_-\|holin	phage holin family protein	A0A0A7S099	Clostridium_phage	9.6e-34	56.7
WP_003445000.1\|4282838_4289741_-	carbohydrate binding domain-containing protein	M9Q2I5	Clostridium_phage	1.2e-62	39.7
4288800:4288817	attL	NA	NA	NA	NA
WP_003444998.1\|4289767_4290145_-	hypothetical protein	M9Q2L1	Clostridium_phage	1.7e-22	47.2
WP_034830556.1\|4290210_4290480_-	hypothetical protein	NA	NA	NA	NA
WP_003444994.1\|4290659_4291007_-	hypothetical protein	M9Q2F8	Clostridium_phage	6.8e-31	58.3
WP_003444992.1\|4291017_4295145_-	transglycosylase SLT domain-containing protein	M9Q251	Clostridium_phage	7.5e-100	46.7
WP_003444989.1\|4295185_4295605_-	hypothetical protein	M9Q2L2	Clostridium_phage	5.9e-21	60.9
WP_034830554.1\|4295665_4295974_-	bacteriophage Gp15 protein	M9Q2I4	Clostridium_phage	8.7e-38	73.3
WP_003444987.1\|4295988_4296318_-	hypothetical protein	NA	NA	NA	NA
WP_003444986.1\|4296339_4296795_-	hypothetical protein	M9Q1I1	Clostridium_phage	1.1e-47	59.7
WP_003444985.1\|4296805_4297192_-	hypothetical protein	M9Q2F6	Clostridium_phage	2.6e-47	68.0
WP_003444984.1\|4297191_4297575_-	hypothetical protein	M9Q249	Clostridium_phage	8.3e-38	64.6
WP_003444983.1\|4297574_4297901_-	hypothetical protein	M9Q2I3	Clostridium_phage	4.1e-30	54.3
WP_003444966.1\|4297909_4298269_-	hypothetical protein	M9Q2K9	Clostridium_phage	3.7e-32	56.7
WP_003444957.1\|4298271_4298559_-	hypothetical protein	NA	NA	NA	NA
WP_003444955.1\|4298569_4299535_-	hypothetical protein	A0A1J0MCK3	Streptomyces_phage	4.4e-88	55.2
WP_003444953.1\|4299550_4300150_-	phage scaffolding protein	S5MUG0	Brevibacillus_phage	2.9e-29	42.6
WP_003444951.1\|4300288_4300453_+	hypothetical protein	NA	NA	NA	NA
WP_143756604.1\|4300435_4300636_-	hypothetical protein	NA	NA	NA	NA
WP_003444947.1\|4300646_4300889_-	hypothetical protein	NA	NA	NA	NA
WP_003444945.1\|4300956_4301280_-	hypothetical protein	NA	NA	NA	NA
WP_003444943.1\|4302915_4304421_-	hypothetical protein	M9Q246	Clostridium_phage	1.3e-182	63.0
WP_034830630.1\|4304423_4305815_-\|terminase	phage terminase large subunit	A0A090EUA8	Clostridium_phage	2.0e-198	72.9
WP_034830628.1\|4305807_4306329_-\|transposase	transposase	A0A0A7RTH0	Clostridium_phage	2.0e-58	73.3
WP_003444940.1\|4306545_4307094_-	hypothetical protein	I2E8Y5	Clostridium_phage	8.6e-12	30.2
WP_003444939.1\|4307106_4308471_-	DEAD/DEAH box helicase	A0A1S7FYY5	Listeria_phage	1.7e-162	62.1
WP_003444938.1\|4308467_4308746_-	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	3.1e-18	52.2
WP_003444935.1\|4309017_4311444_-	putative virulence-associated protein E	A0A0A7RTG3	Clostridium_phage	0.0e+00	79.2
WP_155760405.1\|4311478_4311625_-	hypothetical protein	NA	NA	NA	NA
WP_003444933.1\|4311904_4312930_-	nucleoid-associated protein	J9QE81	Clostridium_phage	2.1e-43	33.1
WP_003444932.1\|4312944_4314903_-	DNA polymerase	A0A0A7RTL3	Clostridium_phage	0.0e+00	78.2
WP_003444931.1\|4314907_4315468_-	DUF2815 family protein	A0A0A7RVM4	Clostridium_phage	4.4e-88	84.9
WP_003444930.1\|4315589_4316753_-	DUF2800 domain-containing protein	A0A0A7S066	Clostridium_phage	6.2e-145	66.8
WP_003444929.1\|4316754_4317204_-	hypothetical protein	A0A0A7RTD8	Clostridium_phage	1.6e-08	32.3
WP_003444928.1\|4317239_4317500_-	hypothetical protein	NA	NA	NA	NA
WP_003444927.1\|4317513_4317975_-	hypothetical protein	NA	NA	NA	NA
WP_003444925.1\|4318295_4318907_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_003444924.1\|4318893_4319160_-	sporulation transcriptional regulator SpoIIID	M9Q261	Clostridium_phage	8.4e-13	49.3
WP_003444922.1\|4319290_4319533_-	hypothetical protein	NA	NA	NA	NA
WP_003444920.1\|4319566_4319707_-	hypothetical protein	NA	NA	NA	NA
WP_003444918.1\|4319872_4320040_-	hypothetical protein	Q8SBM7	Clostridium_phage	8.9e-13	64.2
WP_003444916.1\|4320056_4320305_-	helix-turn-helix transcriptional regulator	Q8SBM9	Clostridium_phage	4.4e-16	59.7
WP_003444915.1\|4320491_4320932_+	helix-turn-helix transcriptional regulator	Q8SBN0	Clostridium_phage	7.3e-22	57.8
WP_003444914.1\|4320965_4321427_+	hypothetical protein	A0A0A7RVV2	Clostridium_phage	2.6e-46	57.9
WP_003444913.1\|4321518_4322568_+\|integrase	site-specific integrase	Q8SBN2	Clostridium_phage	1.1e-127	63.8
WP_003444912.1\|4322639_4323971_-	replicative DNA helicase	O80281	Escherichia_phage	4.2e-105	47.7
WP_174548956.1\|4323994_4325917_-\|protease	ATP-dependent protease, Lon family	A0A0R6PGP8	Moraxella_phage	1.0e-22	23.2
4335232:4335249	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP013018

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection