CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP017783	Rhodobacter sp. LPB0142 plasmid pEJ02, complete sequence	0 crisprs	NA	0	4
NZ_CP017784	Rhodobacter sp. LPB0142 plasmid pEJ03, complete sequence	0 crisprs	NA	0	0
NZ_CP017781	Rhodobacter sp. LPB0142, complete genome	3 crisprs	DEDDh,WYL,csa3,PD-DExK	1	7
NZ_CP017782	Rhodobacter sp. LPB0142 plasmid pEJ01, complete sequence	0 crisprs	DEDDh	0	4

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 2040

Rhodobacter_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_156894477.1\|667_973_+	hypothetical protein	NA	NA	NA	NA
WP_071167471.1\|969_2040_-	replication initiator protein A	A0A0K1Y6J9	Rhodobacter_phage	1.4e-63	40.7

DBSCAN-SWA_2

6911 : 16386

Escherichia_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071167476.1\|6911_8843_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	1.3e-33	25.5
WP_156894478.1\|8808_11199_+	hypothetical protein	NA	NA	NA	NA
WP_071167477.1\|11620_12505_+	DUF1738 domain-containing protein	A0A1V0EEV1	Caulobacter_phage	2.5e-53	44.3
WP_071167478.1\|12687_12987_-	HigA family addiction module antidote protein	A0A0N7BS23	Escherichia_phage	9.1e-08	36.0
WP_071167479.1\|12996_13272_-	plasmid maintenance system killer	A0A2L1IV28	Escherichia_phage	4.1e-15	45.7
WP_083392820.1\|13664_14684_+	DUF3363 domain-containing protein	NA	NA	NA	NA
WP_083392702.1\|15030_16386_-\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	1.3e-45	29.7

DBSCAN-SWA_3

19491 : 20706

Salmonella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029074208.1\|19491_20706_+	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	1.2e-18	28.3

DBSCAN-SWA_4

24673 : 28956

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_083392702.1\|24673_26029_-\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	1.3e-45	29.7
WP_083392821.1\|26116_26806_+	HAD family hydrolase	NA	NA	NA	NA
WP_156894479.1\|26805_27477_+	hypothetical protein	NA	NA	NA	NA
WP_156894480.1\|27602_28292_+	hypothetical protein	A0A2H4J456	uncultured_Caudovirales_phage	1.0e-41	45.3
WP_071167481.1\|28416_28956_+	recombinase family protein	A0A0C4UR34	Shigella_phage	3.8e-36	45.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP017781

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017781_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017781_1

834064-834202

Orphan

Consensus_repeat	Method
CCCGAAGCGCCCGCCGAGACCGCGCCCGAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017781_1

>merge|NZ_CP017781|1|834064-834202|CRISPRCasFinder
CCGCAGGCCCCCGCACAGCCCGCCACCGAGGCGCCCGCCGAGGCGCAACCCGAAGCGCCCGCCGAGACCGCGCCCGAGCAAAGCCCGCCGCCGGAGGCCAAACCCGCCCCCGAAGCGCCCGCCGAGCCCGCGCCCGAGC

>NZ_CP017781|1|1|834064-834202|CRISPRCasFinder
CCGCAGGCCCCCGCACAGCCCGCCACCGAGG	CGCCCGCCGAGGCGCAACCCGAAGCGCCCGCCGAGACCGCGCCCGAGCAAAGCCCGCCGCCGGAGGCCAAACCCGCC
CCCGAAGCGCCCGCCGAGCCCGCGCCCGAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017781.1\|WP_068767126.1\|830871_831459_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380061
NZ_CP017781.1\|WP_068767128.1\|829129_830431_-\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NZ_CP017781.1\|WP_071165606.1\|837143_837986_+\|tol-pal-system-protein-YbgF	unknown	unknown	gnl\|CDD\|188247
NZ_CP017781.1\|WP_068767129.1\|828047_829013_-\|class-II-fructose-bisphosphatase	unknown	unknown	gnl\|CDD\|236536
NZ_CP017781.1\|WP_068767125.1\|831487_832120_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_068767123.1\|832632_833328_+\|protein-TolQ	unknown	unknown	gnl\|CDD\|131843
NZ_CP017781.1\|WP_071165610.1\|844714_845605_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|184558
NZ_CP017781.1\|WP_068767114.1\|844412_844718_+\|chorismate-mutase	unknown	unknown	gnl\|CDD\|214841
NZ_CP017781.1\|WP_068767251.1\|842689_844372_+\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|376511
NZ_CP017781.1\|WP_156894428.1\|838006_839200_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NZ_CP017781.1\|WP_156894427.1\|830523_830733_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235082
NZ_CP017781.1\|WP_068767130.1\|826112_827858_-\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_CP017781.1\|WP_068767122.1\|833331_833841_+\|ExbD/TolR-family-protein	unknown	unknown	gnl\|CDD\|274306
NZ_CP017781.1\|WP_068767124.1\|832116_832518_+\|tol-pal-system-associated-acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|274304
NZ_CP017781.1\|WP_068767117.1\|839278_841159_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
NZ_CP017781.1\|WP_071165603.1\|825043_825613_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_156894316.1\|835235_836555_+\|Tol-Pal-system-protein-TolB	unknown	unknown	gnl\|CDD\|235351
NZ_CP017781.1\|WP_071165609.1\|842004_842592_+\|sulfurase	unknown	unknown	unknown
NZ_CP017781.1\|WP_068767120.1\|836617_837139_+\|peptidoglycan-associated-lipoprotein-Pal	unknown	unknown	gnl\|CDD\|274307
NZ_CP017781.1\|WP_071165608.1\|841210_842005_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|226591

Protein	Function_ID	Function_description	E-value
NZ_CP017781.1\|WP_068767126.1\|830871_831459_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	1.19874e-30
NZ_CP017781.1\|WP_068767128.1\|829129_830431_-\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NZ_CP017781.1\|WP_068767129.1\|828047_829013_-\|class-II-fructose-bisphosphatase	gnl\|CDD\|236536	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed.	0
NZ_CP017781.1\|WP_068767130.1\|826112_827858_-\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	4.21421e-179
NZ_CP017781.1\|WP_068767123.1\|832632_833328_+\|protein-TolQ	gnl\|CDD\|131843	TIGR02796, Protein_TolQ, TolQ protein. TolQ is one of the essential components of the Tol-Pal system. Together with TolR, it harnesses protonmotive force to energize TolA, which spans the periplasm to reach the complex of TolB and Pal at the outer member. The tol-pal system proves to be important for maintaining outer membrane integrity. Gene pairs similar to the TolQ and TolR gene pair often number several per genome, but this model describes specificially TolQ per se, as found in tol-pal operons. A close homolog, excluded from this model, is ExbB of the ExbB/ExbD/TonB protein complex, which powers transport of siderophores and vitamin B12 across the bacterial outer membrane. The Tol-Pal system is exploited by colicin and filamentous phage DNA to enter the cell. It is also implicated in pathogenesis in several bacterial species [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	4.34952e-103
NZ_CP017781.1\|WP_071165610.1\|844714_845605_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|184558	PRK14188, PRK14188, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NZ_CP017781.1\|WP_068767114.1\|844412_844718_+\|chorismate-mutase	gnl\|CDD\|214841	smart00830, CM_2, Chorismate mutase type II. Chorismate mutase, catalyses the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine..	1.28726e-18
NZ_CP017781.1\|WP_068767251.1\|842689_844372_+\|formate--tetrahydrofolate-ligase	gnl\|CDD\|376511	pfam01268, FTHFS, Formate--tetrahydrofolate ligase.	0
NZ_CP017781.1\|WP_156894428.1\|838006_839200_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	9.91437e-61
NZ_CP017781.1\|WP_156894427.1\|830523_830733_-\|hypothetical-protein	gnl\|CDD\|235082	PRK02888, PRK02888, nitrous-oxide reductase; Validated.	0.00149897
NZ_CP017781.1\|WP_068767122.1\|833331_833841_+\|ExbD/TolR-family-protein	gnl\|CDD\|274306	TIGR02801, Protein_TolR, TolR protein. The model describes the inner membrane protein TolR, part of the TolR/TolQ complex that transduces energy from the proton-motive force, through TolA, to an outer membrane complex made up of TolB and Pal (peptidoglycan-associated lipoprotein). The complex is required to maintain outer membrane integrity, and defects may cause a defect in the import of some organic compounds in addition to the resulting morphologic. While several gene pairs homologous to talR and tolQ may be found in a single genome, but the scope of this model is set to favor finding only bone fide TolR, supported by operon structure as well as by score. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	1.25157e-47
NZ_CP017781.1\|WP_068767124.1\|832116_832518_+\|tol-pal-system-associated-acyl-CoA-thioesterase	gnl\|CDD\|274304	TIGR02799, Acyl-CoA_thioesterase_YbgC, tol-pal system-associated acyl-CoA thioesterase. The tol-pal system consists of five critical genes. Inner membrane proteins TolQ and TolR convert protomotive force to energy that is transduced through TolA to an outer membrane complex of TolB and Pal. The system is known to be required to maintain outer membrane integrity. In a system with several homologous parts, ExbB and ExbD transduces energy through TonB to a variety of outer membrane proteins, many of which are siderophore receptors. The tol-pal system therefore may also be involved in transport. This family consists of a protein nearly always found in operons with the genes of the tol-pal system. The significance of this thioesterase to the tol-pal system is unclear, but either of two observations may be relevant. First, Pal, or peptidoglycan-associated lipoprotein, has a conserved N-terminal cleavage and acylation that makes it a lipoprotein. Second, the tol-pal system is implicated not only in the import of certain organics but also in the maintenance of outer membrane integrity (by an unknown mechanism).	2.44237e-57
NZ_CP017781.1\|WP_068767117.1\|839278_841159_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP017781.1\|WP_156894316.1\|835235_836555_+\|Tol-Pal-system-protein-TolB	gnl\|CDD\|235351	PRK05137, tolB, Tol-Pal system protein TolB.	0
NZ_CP017781.1\|WP_071165606.1\|837143_837986_+\|tol-pal-system-protein-YbgF	gnl\|CDD\|188247	TIGR02795, Uncharacterized_protein_in_oprL_3'region, tol-pal system protein YbgF. Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.	2.97767e-36
NZ_CP017781.1\|WP_068767120.1\|836617_837139_+\|peptidoglycan-associated-lipoprotein-Pal	gnl\|CDD\|274307	TIGR02802, Peptidoglycan-associated_lipoprotein, peptidoglycan-associated lipoprotein. Members of this protein are Pal (also called OprL), the Peptidoglycan-Associated Lipoprotein of the Tol-Pal system. The system appears to be involved both in the maintenance of outer membrane integrity and in the import of certain organic molecules as nutrients. Members of this family contain a hydrodrophobic lipoprotein signal sequence, a conserved N-terminal cleavage and modification site, a poorly conserved low-complexity region, together comprising about 65 amino acids, and a well-conserved C-terminal domain. The seed alignment for this model includes only the conserved C-terminal domain.	7.03173e-57
NZ_CP017781.1\|WP_071165608.1\|841210_842005_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|226591	COG4106, Tam, Trans-aconitate methyltransferase [General function prediction only].	1.93647e-71

>NZ_CP017781.1|WP_068767122.1|833331_833841_+|ExbD/TolR-family-protein
MGAGVMKKSGGGGRRGRRGRAGQGAMSEINVTPMVDVMLVLLIIFMVAAPMMTVGVPLELPKTAAKAVPTEQEEPLTISLQLDGSISLMNEPVPEEELVTRLAAVAGQRESDKVYLRADGGIEYARVVQVMGALNAGGFNNIVLVTDPGGPSLGSGQAPAPAGAAPAAN
>NZ_CP017781.1|WP_068767123.1|832632_833328_+|protein-TolQ
METEALTMAPQMDFSLLALFLRASFTVKIVMMLLTFASFWSWSIIVRKFITFRAARHEADAFDRAFWSGEPLDELFDQIGPNPDGPSQRIFAAGMLEWRRSHRQDGELIAGAQARIDRSMNVAIAKETETLNSGLSFLATVGSTAPFVGLFGTVWGIKVAFEEIAISQNTSLAVVAPGISEALVATAIGLLAAIPAVIFYNKLSADADKILAGYDAFADEFATILSRQLDA
>NZ_CP017781.1|WP_068767124.1|832116_832518_+|tol-pal-system-associated-acyl-CoA-thioesterase
MTHELAIRVYYEDTDLAGIVYYANYLKFIERGRSEYVRALGIDQAALKRGHGIVFAVRRVEADYLRPAKYDDELTVKTDLVAETGARLVLDQSVWRGAEKLFTATVTIVCLSETGAPTRLPADVRRKFAPPVH
>NZ_CP017781.1|WP_068767125.1|831487_832120_+|hypothetical-protein
MTAEAVAALFTRGGGEYLFARWGRPIVPVVFGVDAATLATVKGAVEAVVTLAGHKMAETDPELGANLMIFFFRDWQELLEVPNLDQLIDGLSDLVARLDDAGANQYRVFRFDAEGAIRACFSFIRMDGALDEVPAETIALNQAVQMILLWSDRAFLEHAPLASARGVTVLRPEIAALIAAGYDGVLPASARDPSHALRLAARLKPVEDAQ
>NZ_CP017781.1|WP_068767126.1|830871_831459_+|TetR/AcrR-family-transcriptional-regulator
MARKTGSHSEITGPRVRAEAQRLFARHGFAAVSMRQIAAAVGVQAGALYLYTPDKETLLFQLLETHMKELLAAWQAEPRGQGPLEALEAFVRFHIRYNGERPEVVFLSYMELRNLGPENFAAIEALRRAYETELETILKAGQAAGMILVPDTKLATMAIIAMLTGVNTWFREGGRLGRAAVEDIYWDMVRKAVGA
>NZ_CP017781.1|WP_156894427.1|830523_830733_-|hypothetical-protein
MRPALLCAALACASLAGCSAGDPAAFPALMPTAQIEAEAAAELTPHPAPGLEARAASLRTRAAWLRTQN
>NZ_CP017781.1|WP_068767128.1|829129_830431_-|homoserine-dehydrogenase
MSAPAQATPLRLGIAGLGTVGIGVVKIVQRHADLLAARSGRPVVITAVCARDRTKNRDADLSGYAWETDAVALAGRDDVDVFVELMGGHEGAARHATEAALRAGKNVVTANKALLAHHGQELAEMAEAAGAVIRFEAAVAGGIPVIKALTEGLAGNQIRRVMGVMNGTCNYILTRMETAGLPYDTVFEEARQLGYLEADPNLDVGGIDAGHKLAILAAIAFGTRVSFEAVKLEGIGRISIDDIRRAGDMGYKIKLLGVAQMTGRGLEQRMTPCLVPASSPLGQLHGGTNMVVIEGDSVGQIVLRGAGAGEGPTASAVMGDVMDLARGLKLPTFGMPAAQLAAPTPAVTSAPASYYLRLHLLDKPGALAKVATVLGEAGVSISRMRQYGHDDSAAPVLIVTHKTTPEAISLAIAGFPATGVVEGEPVALRIEEL
>NZ_CP017781.1|WP_068767129.1|828047_829013_-|class-II-fructose-bisphosphatase
MTPPTDFNDRMLSLGLARVSEAAAHASARLIGRGDEKAADQAAVNAMRDQLNQLDIKGVVVIGEGERDEAPMLYIGEEVGTGQGPAVDIALDPLEGTTLTAKDMPNALTVVAMAPRGTLLHAPDVYMDKLAIGPGYAKDIVSLEMTPTERVLALAKAQGVKPEDITCCILERPRHEDLIREVRETGAAIRLITDGDVAGVIHCAEPDFTGIDMYMGSGGAPEGVLAASALKCMGGQMWGRLLFRNDDERGRAAKAGITDLDKIYTRDELVKSDVIFAATGVTNGSIVRGVKREPTYIETETILMRSKTGSVRRVLYRNPVK
>NZ_CP017781.1|WP_068767130.1|826112_827858_-|single-stranded-DNA-specific-exonuclease-RecJ
MTAFLGVERSLTDRHWVGPSAEADRLAEAMARDTRLPLPLARILVARGVGPGEAAGFLEPTLRELLPDPRALKDMEAAAARFLAAVKSREKIAVFADYDVDGGSSAALLLSWLRAMGREATLYIPDRIDEGYGPNVPAMAGLAREHGLIVCVDCGTLSHEPVAAAKGADVVILDHHLGAETLPPALACVNPNRQDESGDLGHLCAASVVFLMLVEANRQLRADGVQGPDLMALLDLVALATVADVAPLIGVNRALVRQGLKVMARRERPGLVALADVARMDRAPSAYHLGFLLGPRVNAGGRIGAADLGARLLATTDPAEAEALAARLDALNTERREIENRVREAALAQAEARGLEGPLVWAAGEGWHPGVVGIVAARLKEATNRPAVVIGLEGGVGKGSARSVAGVDLGAAVQRVAAEGLLLKGGGHKMAAGLTVAEDQLEPAMARLAELLARQGAGAGGPRDLRLDGMLLPGAATPALIEDLERAGPFGQGAPAPRFAFPAMEIRAPRPIGESHLRFTFSDGMGARIDAVAFGAFDGPLGPALASPGAGRFHLAGRLEINTWGGRAKVQLRLEDAARAI
>NZ_CP017781.1|WP_071165603.1|825043_825613_-|hypothetical-protein
MTHERMTISLYDVASALNVSEAAARGWLLRSGAIPHFARSRYPALMRPDEIIVRLRGARKRGCTSNEAFAILQIDAQRRDAEPGIPFGADCERRAAELRACLTELELSRYLAVRGALHAGLIGALWAEAFKADVGVLLDLALIHPSVMLYVFGGDHSELPQSADAWRHWGHAFAVPQLATLRHLQKEAA
>NZ_CP017781.1|WP_156894316.1|835235_836555_+|Tol-Pal-system-protein-TolB
MMRIALAALAALMIGPGLAAAQQGPLHIEITDGVIEPMPYALPTFVAETGDAGQMASDITRVIAADLSGTGLFREIPESAHIQRFSAFETPVSYPDWQAINAQALIVGGVSMQGGKVVVKFRLFDIYSGQQLGDGQQLAASPASWRRLAHKVADVIYSRITGEGGYFDSRVVFVSETGPKDKRQKRLALADYDGANLNYLTDSSAIVLAPRFSPAGDKVLYTTFETGFPRIKLLNVGNVAGTLLPEVPGTMTFAPRFSPDGASIVYSMEQGGNTDLYKMSVSGGAPVRLTNSPAIETAPSYSPDGSRIVFESDRSGTQQLYIMSASGGEPTRISFGDGRYGTPVWSPRGDLIAFTKQAGGRFHIGVMRTDGSEERLLTASFLDEGPTWSPNGRVIMFTRESPGAGGGAGLYTVDISGRNLKKVDGIGGASDPAWSPLLP
>NZ_CP017781.1|WP_068767120.1|836617_837139_+|peptidoglycan-associated-lipoprotein-Pal
MTFAPKALLLLTVLGLAACNNPDKYGAGNGVVDPGGAYGDGGVSQGSINDPNSPAYFNQKIGDMVNFMVDQSTLSDEARATLTQQAQWLNGHTNYNAIIEGHADEQGTREYNLALGARRANAAQEFLISQGVAPNRLRTVSYGKERPLAVCSTEECYYKNRRAVTVISLGAGS
>NZ_CP017781.1|WP_071165606.1|837143_837986_+|tol-pal-system-protein-YbgF
MRRGLKLGALALALAAPVAPAMAADAQTLADIRAELQSLAGEIQGLRQELVASGAQGMQAAGGASALQRMDAMEAELSQLTSRTEELGNRIDRVVSDGSNRLGDLEFRLCELEEGCDVSTIGQTPLGGAPASAPVTAPAAGATPAPAPATSSLAMNEQSDFDRAKGVLGQGDFRGAADQFATFAETYPGGPLTGEAMYLRGDALRQAGDTAGAARAWLDAFSADPTGTRAPDNLLGLGQSLGALGQKSEACATLGQVPVRFPAAPAATQAQTAMQGLGCP
>NZ_CP017781.1|WP_156894428.1|838006_839200_+|tRNA-lysidine(34)-synthetase-TilS
MARAAFDPDAAPACVGVAVSGGSDSLATLSLLARHYRVAAVTVDHGLRPEAAQEAAGVAAYCGARGIPHEILRWEGPAPAGNLMDQARRARLSLIGGWARGRGITDVALGHTADDQAETFLMRLGRRAGLEGLAGMRRRFVAEGVLWHRPFLTAPRAALRAHLTAEGIAWVEDPSNSDPRFARVRARAALAGLGAVGITAEGLAEVTAHLAAAEALIAEDLYRWAAQNLREEAGDLVVAGAALAALAPERRRRLLNAALRWVAGAAYGPRAAALARIVAAPGPATLHGCRITAARGLLRITREAAASAPRAPAAAGLWDRWRLAGPAAPGLEIGPLGAAGLARITDWRAGPLPRPSLLASPAIWAGETLIAAPLARPEGDWRATPACGSFHATLIRR
>NZ_CP017781.1|WP_068767117.1|839278_841159_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MGNARNFAFWIVLFVLILALFNLFGDGQTSMNSKQVAYSDFIAQVDKGEVKSVQLDGEDVRYQVADGSTFSTVKPEADEIAKTLIDKGIQVRVTKQAQSGFMSLLGMWVPFIVLIGVWVFFMNRMQGGGKGGAMGFGKSKAKLLTEKQGRVTFDDVAGIDEAKEELEEIVEFLRNPQKFSRLGGKIPKGALLVGPPGTGKTLLARAIAGEAGVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIVFIDEIDAVGRARGVGIGGGNDEREQTLNQLLVEMDGFEANEGIIIVAATNRRDVLDPALLRPGRFDRQIHVPNPDIKGREKILSVHARKVPTGPDVDLRVIARGTPGFSGADLANLVNEAALMAARVGRRFVTMEDFENAKDKVMLGVERRSMVLTPEQKEMTAYHEAGHALVGLKLPKCDPVYKATIIPRGQALGMVVSLPEMDKLNYHKDEAKQKIAMTMAGKAAEILKWGEEHVSNGPAGDIMQASAIARAMVMRWGMSDKVGNIDYSEAHEGYQGNTGGFSVSTKTKELIEDEVRGLIETGYLEARRILEENREEWERLAQGLLEYETLTGEEIRKVMAGEPIHGGEDVSAVSLPSVSSKPKSTQDEAGPAV
>NZ_CP017781.1|WP_071165608.1|841210_842005_+|methyltransferase-domain-containing-protein
MGKAKADGDWNPAAYARFGGLRLRPALDLLARVGALPEKGAVVDLGCGAGAVAPALKARWPARKLLGVDASPAMLVEAAACGAYRRCDLADIATWAPRKPAALIFSNAVLHWLPDHAGLIARLAGCLAPGGTLAVQMPRQDFAPSHRFLREFAAEMFSDRFDLAAWAPPVAEPADYARLLAPLGAAEVWQTDYLQRLAPAEGGHPVRRFTESTTLRPFAEKLDPAELARLLARYDEALGAAYPAEPDGSVLFPFRRVFFTLKVS
>NZ_CP017781.1|WP_071165609.1|842004_842592_+|sulfurase
MPALKATRFSGEIVFLGIVPAGQGLASQPIERMELGFEGAAGESHAGRTRASCSRVTSQHPLGTEIANTRQISILSEEELAETAFALHIPRVAPEWVGASIVLRGLPDLSHLPPSSRLQGPDGATLVVDMENRACVLPGKVIEHHHPGTGARYKPAATGRRGVVAWVERPGVLELGQSLTLHIPDQRAWEFLRDA
>NZ_CP017781.1|WP_068767251.1|842689_844372_+|formate--tetrahydrofolate-ligase
MTATPQAPQSDLEIARAARLAPMPEIAAKLGIPEAALIPFGRDKAKVDPGALAPRGREGRLILVTAITPTAAGEGKTTTTVGLGDGLARIGKRTAICIREASLGPNFGMKGGAAGGGRAQVVPMEAMNLHFTGDFHAVTAAHNLLAAMVDNHIYWGNTPAIDPRRVTWRRVLDVNDRALREIVVGLGGVANGYAHEAGFDITAASEVMACLCLATDLADLEARLGRIVVGYGPDRAPVTCAEVGAAGAMTVLLKDALLPNLVQTLEGTPAFVHGGPFANIAHGCNTLIATRTALGLADYVVTEAGFGADLGAEKFFDIKCRIGGLKPAAAVIVATIRALKSAGGVAKAELSAPAPEALRRGCANLGRHIANTKGFGVPVVVAINAFSADRPEEIAQIQAFAAEQGVEAIVARHWAEGGAGAEDLARKVVALAEAGAAFAPLYPADLGLFEKIDTIARRIYHAGEVMADKSVRAQLHAWEAAGYRDLPVCMAKTPYSFSSDPGLAGAPQGHTLPIREVRLSAGAGFVVAICGEIMTMPGLPRHPAAKAIGLDAEGRIAGLF
>NZ_CP017781.1|WP_068767114.1|844412_844718_+|chorismate-mutase
MKDPREIASMAELRAEIDAHDAKIVAMLADRARLIDRAAELKPAEGMPARITARVNAVLDNVRAEAQARGLDPALVEGIWRGLIEWSIAREEKVLGKGEAE
>NZ_CP017781.1|WP_071165610.1|844714_845605_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MTATIIDGKAFAANVRAQVAGHVTRLKEEQGLTPGLAVVLVGEDPASEVYVRNKGIQTREAGMASFEHKLDATTSEAELLDLIGKLNADPAVHGILVQLPLPGHLDADLVINAIDPAKDVDGFHISNVGLLGTGQKAMVPCTPLGCLMMLRDHLGSLSGLNAVVVGRSNIVGKPMAQLLLGESCTVTIAHSRTKDLASVCRGADILVAAVGRPEMIPGDWVKPGATVIDVGINRIERDGKTKLVGDVDFASAVEVAGAITPVPGGVGPMTIACLLANTLTAFCRANGLPEPQGLTA

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Crispr_ID: NZ_CP017781_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017781_2

1444127-1444232

Orphan

Consensus_repeat	Method
AGTGTCCGAAATCCGGACACGGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP017781_2

>merge|NZ_CP017781|2|1444127-1444232|CRISPRCasFinder
AGTGTCCGAAATCCGGACACGGCTTTCGGCATTTTCCGGACACGGGTCAGCCGGAAAATCGGACACGGCTTCCCCGCCAAACCCGTGTCCGAAATCCGGACACGGC

>NZ_CP017781|2|2|1444127-1444232|CRISPRCasFinder
AGTGTCCGAAATCCGGACACGGC	TTTCGGCATTTTCCGGACACGGG
TCAGCCGGAAAATCGGACACGGC	TTCCCCGCCAAACC
CGTGTCCGAAATCCGGACACGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017781.1\|WP_071167163.1\|1442377_1442881_+\|DNA-mismatch-endonuclease-Vsr	unknown	unknown	gnl\|CDD\|226250
NZ_CP017781.1\|WP_156894336.1\|1452253_1453011_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP017781.1\|WP_071165939.1\|1435486_1436461_-\|PD-(D/E)XK-motif-protein	unknown	unknown	gnl\|CDD\|379594
NZ_CP017781.1\|WP_071165945.1\|1445009_1445249_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_156894335.1\|1448342_1450040_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_068765065.1\|1453045_1453231_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226609
NZ_CP017781.1\|WP_071165946.1\|1446113_1446716_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_071165944.1\|1444617_1445013_-\|VRR-NUC-domain-containing-protein	unknown	unknown	gnl\|CDD\|214959
NZ_CP017781.1\|WP_156894334.1\|1445852_1446017_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_071165937.1\|1431757_1433020_-\|DNA-methylase	unknown	unknown	gnl\|CDD\|319260
NZ_CP017781.1\|WP_071165940.1\|1436447_1439183_-\|Z1-domain-containing-protein	unknown	unknown	gnl\|CDD\|378453
NZ_CP017781.1\|WP_071165941.1\|1439179_1440673_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|372641
NZ_CP017781.1\|WP_156894434.1\|1440756_1442310_-\|DNA-(cytosine-5-)-methyltransferase	unknown	unknown	gnl\|CDD\|223348
NZ_CP017781.1\|WP_071165947.1\|1446719_1447991_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP017781.1\|WP_071167164.1\|1445245_1445494_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP017781.1\|WP_071165950.1\|1450036_1451731_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_071165942.1\|1442939_1443617_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_071165938.1\|1433420_1435490_-\|AIPR-family-protein	unknown	unknown	gnl\|CDD\|378452
NZ_CP017781.1\|WP_083392612.1\|1429889_1430402_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198380
NZ_CP017781.1\|WP_071165936.1\|1430432_1431761_-\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|319260

Protein	Function_ID	Function_description	E-value
NZ_CP017781.1\|WP_071167163.1\|1442377_1442881_+\|DNA-mismatch-endonuclease-Vsr	gnl\|CDD\|226250	COG3727, Vsr, DNA G:T-mismatch repair endonuclease [DNA replication, recombination, and repair].	4.23553e-57
NZ_CP017781.1\|WP_071165939.1\|1435486_1436461_-\|PD-(D/E)XK-motif-protein	gnl\|CDD\|379594	pfam14390, DUF4420, Putative PD-(D/E)XK family member, (DUF4420). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 310 and 334 amino acids in length. Advanced homology-detection methods supported with superfamily-wide domain architecture and horizontal gene transfer analyses have established this family to be a member of the PD-(D/E)XK superfamily.	9.16193e-82
NZ_CP017781.1\|WP_068765065.1\|1453045_1453231_+\|hypothetical-protein	gnl\|CDD\|226609	COG4124, ManB, Beta-mannanase [Carbohydrate transport and metabolism].	1.57864e-12
NZ_CP017781.1\|WP_156894336.1\|1452253_1453011_+\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.6998e-23
NZ_CP017781.1\|WP_071167164.1\|1445245_1445494_-\|DNA-binding-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.00295738
NZ_CP017781.1\|WP_071165937.1\|1431757_1433020_-\|DNA-methylase	gnl\|CDD\|319260	cd16403, ParB_N_like_MT, ParB N-terminal-like domain, some attached to C-terminal S-adenosylmethionine-dependent methyltransferase. This family represents domains related to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, fused to a variety of C-terminal domains, including S-adenosylmethionine-dependent methyltransferase-like domains. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	2.40028e-47
NZ_CP017781.1\|WP_071165940.1\|1436447_1439183_-\|Z1-domain-containing-protein	gnl\|CDD\|378453	pfam10593, Z1, Z1 domain. This uncharacterized domain was identified by Iyer and colleagues. It is found associated with a helicase domain of superfamily type II.	3.13895e-98
NZ_CP017781.1\|WP_156894434.1\|1440756_1442310_-\|DNA-(cytosine-5-)-methyltransferase	gnl\|CDD\|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	5.9979e-27
NZ_CP017781.1\|WP_071165947.1\|1446719_1447991_-\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.3365e-39
NZ_CP017781.1\|WP_071165941.1\|1439179_1440673_-\|ATP-binding-protein	gnl\|CDD\|372641	pfam13589, HATPase_c_3, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.	2.79898e-35
NZ_CP017781.1\|WP_071165938.1\|1433420_1435490_-\|AIPR-family-protein	gnl\|CDD\|378452	pfam10592, AIPR, AIPR protein. This family of proteins was identified in as an abortive infection phage resistance protein often found in restriction modification system operons.	5.24128e-110
NZ_CP017781.1\|WP_083392612.1\|1429889_1430402_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198380	cd00719, GIY-YIG_SF, GIY-YIG nuclease domain superfamily. The GIY-YIG nuclease domain superfamily includes a large and diverse group of proteins involved in many cellular processes, such as class I homing GIY-YIG family endonucleases, prokaryotic nucleotide excision repair proteins UvrC and Cho, type II restriction enzymes, the endonuclease/reverse transcriptase of eukaryotic retrotransposable elements, and a family of eukaryotic enzymes that repair stalled replication forks. All of these members contain a conserved GIY-YIG nuclease domain that may serve as a scaffold for the coordination of a divalent metal ion required for catalysis of the phosphodiester bond cleavage. By combining with different specificity, targeting, or other domains, the GIY-YIG nucleases may perform different functions.	8.73807e-06
NZ_CP017781.1\|WP_071165944.1\|1444617_1445013_-\|VRR-NUC-domain-containing-protein	gnl\|CDD\|214959	smart00990, VRR_NUC, This model contains proteins with the VRR-NUC domain. It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes, for example StyLTI.	3.00345e-05
NZ_CP017781.1\|WP_071165936.1\|1430432_1431761_-\|site-specific-DNA-methyltransferase	gnl\|CDD\|319260	cd16403, ParB_N_like_MT, ParB N-terminal-like domain, some attached to C-terminal S-adenosylmethionine-dependent methyltransferase. This family represents domains related to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, fused to a variety of C-terminal domains, including S-adenosylmethionine-dependent methyltransferase-like domains. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	2.55878e-46

>NZ_CP017781.1|WP_071165942.1|1442939_1443617_-|hypothetical-protein
MTLQRPIARAGSRSVKRALGVQAALEWAFRIEQAQLELPLPPDVTEEGFGFGLEYVLLQRAVLGCKIDGGQHKIGGYTHEDAEAIAATVAGIPDSLGGKRMAIRVAELARSGLTPDWMPGAIPRCVPTIVKQNQHGTHAGTIVVGTERVRVRGLGDRAKWKTFDILACPVTFSPHPHQIEAARRGYDDWCQALGWVREGLIAGGMLRDVVLTAAMPKALPWKESR
>NZ_CP017781.1|WP_071167163.1|1442377_1442881_+|DNA-mismatch-endonuclease-Vsr
MTDIVDSQTRSRMMAGIRGKDTKPELALRRSLHALGLRYRLHAKGIPGKPDLVLPKFKAVIFVHGCFWHRHPECRYASTPATRPEFWESKFSANVMRDTTVRSELLAAGWRVATIWECALRSETGVTAVGDTVSRWLQGGGRELEMGEKDIGAPKDERSISVVSNQT
>NZ_CP017781.1|WP_156894434.1|1440756_1442310_-|DNA-(cytosine-5-)-methyltransferase
MPATFGIVDLFAGPGGLGEGFASLEAGGQHPFHIGISVEKETSAHRTLSLRAFLRAQVSRHGALPEAFVRFHAGLTEEPDWPEVDAAAWTEATAEARCLELGSEAAAAAIDEAIGRLRKSFDDTILIGGPPCQAYSLVGRARSRGKADYVPEEDHRHYLFREYIRVLDRLRPAAFVMENVKGMLSSTVESRLVFEMLMEDLASLGTGHGHHYELRAIRLADGRATLQEAAKPSDFIVRAEEFGVPQRRHRVIIVGIRSDLAARAVGASVAVSGATRTVEETIGNMPPLRSGISRATDTPAAWQREVAGFAKLLARISKGDEDGALQSEFRAIVDLLKQGAETRRSSGMLPAGYGTSNDDLMRWLERPGLRALAQHETRGHMATDLGRYLFAAAFGKVRRYSPKAADFPLALSPDHRNWHTGVFNDRFRVQLAHEPSTTVTSHISKDGHYFIHSDPLQCRSLTVREAARLQTFPDDYLFLGNRTQQYVQVGNAVPPFLARQIAALVYASLTEADTLDV
>NZ_CP017781.1|WP_071165941.1|1439179_1440673_-|ATP-binding-protein
MQEIVVSRRADATPHAAALIEGLRDIGYSLETAISDIIDNSITAGAHRIEIVTETYSDEPYIAIIDDGEGMTEDELVAAMRPGSRNPLATRDEPDLGRFGLGLKSASFSQCRRLTVVSRRSGQTSAAIWDLDDVAERNEWAVQLPDHFDLIPGIEKLGQKGTLVLWQKLDRLTGGYSHNAAKRAEVINQRIAETERHLRLVFHRFMENAKPLRILLNERLLRPLDPFARKNPATISDPEEKLTLIRGDVEIQSFTLPHHKQMGKTEWEDIGGPEGHLKSQGFYLYRGKRLILHGTWFGLCRQSELTKLSRVRIDIPNSMDADWKIDVKKSSAQLPPVVRDRLKKVIERILAGSKRTYSKRGQKLVDHERLPMWHRIQADGQIRYRPNIEHPAFADFADSLPPDLRRGFFNCIALVGASLPIETLHADMAGTAEQIVPDRVDEDTLAQAVQATLSVLLGARKDIKEIKSLMKDVDPFRSAWEDTERIIAATIETKEDK
>NZ_CP017781.1|WP_071165940.1|1436447_1439183_-|Z1-domain-containing-protein
MKQILSSLEGMTSMYMASQPGPHTAQSIREIIAQLRVMPMFAGQVEDDDAEELARLIEEKYGISMGFGAIVDAEDFRPWLHDARINGEIGDFYWGRYRKLLNLKGLPKSVIDATDEVTDRVLDRLGDPRNLSPWSRRGMVVGHVQSGKTANYTGLICKAADAGYRLIVVIAGIHNNLRNQTQARIDEGFIGRDTGRLAHANKAQRQKIIGVGQFDQREFPVSLTNTLRDFNKATATTNTSQIGQYNVPVVLVIKKNTSTLKNLLEWLKEHSVHQGTQMVSQPMLLIDDEADNASINTAYARDEVTRINGQIRELLSLFHRSCYVGYTATPFANIFIDPDTDDETLKQDLFPRHFIIGLDAPSNYFGAQKVFLDARDQHVRLIDDNEDILPMKHKIDHPVDVLPESLIRAVRAFVVARAIRNARGQQAAHASMLINASRFTDVQGRLRSRVADVVDKMRDAVAVDGAKGKVALRNPEIAALHAVWESEFAEAEGADWPTVQARLHEVLVAARVVEVNASKRSQPLDYDQTGEHGVTVIAVGGFSLSRGLTLEGLTISYFLRNSMMYDTLMQMGRWFGYRPGYEDLCRIWIPADGVGWYAHIHEAMDDLQTQLKRMELAKATPEQFGLAVRSHPESLIVTARNKMGTGREFPMKVGLAGKLVETTRIRTDRDQLDRNRQAGQALAAAIQASGLAPQNPSRGTLFSGVSVDLIRDFLRAFRADASDPLTDPRLMSDYIDARADTELREWDVLFASAQKADATSANLSGIDMRAFGRSVGEPDLRQGVLAISGTSRRVGSPGDERVGLTREQIDAATNAFREERIRDGKPVPETLPPRIFCEVKGRRPLIILRFVEPVVPEELKAKSPYLVLAWSICFPPSEVQGGTVEYIVNTIRMREMFGEEEIEEEALGDTE
>NZ_CP017781.1|WP_071165939.1|1435486_1436461_-|PD-(D/E)XK-motif-protein
MIPNDTPWSGLEAGKVDTRRVSASARWNWFWAVMPRADVALVLQLADLPKPAPELPKLRNLEIRFQTLPGGPILYIRLKDNAQLELFETLCRDVMAAGELADTEAEALERAIGRTFRWHYLLRGGKLEVLSEEAQKGLIGEIEVLKLLISTLGAKPALTAWTGPSGAPKDFELKADCIEVKARRGASQPFVKITNEFQLADVPDRRLWLAVLAVDKVQPPHGRTLTEYVSEVTELLEQTEPSAIMDWDLHLADAGFDIVHDYSAWRWIVSAPDFHAVTEDFPRIAAPVPLGLSAVSYALALSACTPFRTDWGAVQEKLNEADQT
>NZ_CP017781.1|WP_071165938.1|1433420_1435490_-|AIPR-family-protein
MNELEEYHQNLMADIRREADASGVFPVEAFFDRMTERLTEAGELEVADRAYFQSGEGAQRLRIDGYAGDPRDSEGVLGLIVCDFADSDTVQTFGKGDVPPILNPLIRFLKKAKTEEFRDSLNEANPAFQVSDLIITTWSQVTKVKLILISNRQYIGRDDTVKLADIGDVPITWSVWDLARFERFDRSGQAREDMVIDFARDFGAPLPALKASQTGAALESYLLIVPGEQLAAIYDKWGARLLEANVRSFLQARAKTNKGIQKTIKEEPELFFPYNNGLSATADAVSCVRTDDGMAVASISNLQIVNGAQTTGSIHAGLKSAKEQLPQVFVQMKLTVVPSDRSEDIVPKISEYANTQNKVNAADFFSNHPFHIRMEQFSRSVLFPARAGERHDTKWFYERSRGQFVNARPKVKGKAQTDFDIQFPKSQLFSKTDLAKFEFSAAGQPHIVSRGAQKNFAEFAKDIGESWSRSDAKYDELWYKRLVSKAIVFRWLETEVPKQPWYEGGYRANIVTYSMAKVFHDANGEKQVLDLDAIWRRQSVPEALQRALLLAAAEAHDVITHPPAGVRNMSEWAKQQACWNGMKGRTLNYGDDFETCLTLVDTAKAAKRDEKAKKAMTEGINAQAEVVTLGAEFWSGVLAWGRERKRLTPKDMQILEVCASMPRRIPSDLQARHALDVLGRMRDQGFGES
>NZ_CP017781.1|WP_071165937.1|1431757_1433020_-|DNA-methylase
MDLVFAPSQVESWPIARLRPYARNAKMHGDDQVAKIAASMAKFGWTVPCMVADDGELIAGHGRVLAATMLGLTEVPVIRLSHLDEAERRAYRIADNKLTELGEWDEALLRDEIAGLLAEDFDLTLLGISDDELDALLRDPDALGDDDPVEGEDDVPELPVTPVSVPGDLWQVGAHRLICGDSTAADVVGRLLGDVRPLLMVTDPPYGVEYDPSWRNQAGAAKTKRTGKVLNDDRADWREAWALFPGDVAYVWHGALHAATVAESLAAAGFAIRSQIIWAKDRLVLSRGDYHWQHEPCWYAVRAKGKGHWAGDRKQTTLWQIANRDQDADTVHGTQKPVECMRRPILNNSSPGQAVYEPFMGSGTTLIAAETTGRVCFGIELNPAYVDVAIERWQSFTGLEAVLAETGETFAALKAKRLAA
>NZ_CP017781.1|WP_071165936.1|1430432_1431761_-|site-specific-DNA-methyltransferase
MNAPLLPGRIEHWPLARLRPYACNAKTHDADQVAKIAASMAEFGWTVPVLVAADGELIAGHGRILAAAQLGIAEAPVIILGHLTEAQRRAYRIADNKLTELGGWDEALLLEELRGLMAEDFDLGLIGIPEDELDALLHDADDRAPIDDDTADTIPEAPTEPITRPGDIWALGDHRLICGDATDPAVVARLMERAQASLLFTSPPYAQQRDYGAAKEKVGDWDALMQGVFSAAPVTVDAQLLVNLGLVHRDGEWIPYWDGWLDWMRAQGWRRFGWYVWDQGPGLPGDWNGRLAPSHEFIFHFNRQPRKPNKTVESKHAGETLGGGGLRGADGTVHRKTGYGNAIQSHRIPDSVFRIMRHKGGLGAAGSHPAVFPVALVEAVLEAFTGPGDLVFEPFCGSGTQLIAAERTGRRCFAVELDPVYCDVAVRRWEMATGRTACWENK
>NZ_CP017781.1|WP_083392612.1|1429889_1430402_+|GIY-YIG-nuclease-family-protein
MKVTSFGLFWRASEIDWNPGQGNRNGFRLLGRIGANRGNIRVADFRHQQGIYILFDEYGPAYVGLTRAQGLGKRLKDHLTDHLQDKWDRFSWFGFHPIGNPDPRSRILQLNQPDENLTDDTRTTIGDLEALLIRSIGPKRNTAYPGFQGAEEWTQIDYEEQEKYIGRLGA
>NZ_CP017781.1|WP_071165944.1|1444617_1445013_-|VRR-NUC-domain-containing-protein
MMRRGTPEADLQRAVVQALRIALPRTAIIHHCANEITEAGPRGAKRQAILVGMGVHAGFADLMVLCEGRVLFLELKAPKGRLRPEQEAFRDAVLAQEFGWALVRSLDDALGALADHGFTTRIAPPPRRSAP
>NZ_CP017781.1|WP_071165945.1|1445009_1445249_-|hypothetical-protein
MTIQPRTSAWPADRVAEARAVIADVAHHSDLLIRLACNVLVQHGETSAERTEAQRLLVVVDARRPVRLAQREDQGRAAR
>NZ_CP017781.1|WP_071167164.1|1445245_1445494_-|DNA-binding-protein
MKDIQTELDEDIPDLLADWISREQLAWALGLTADTLSRWEARRQGPPCTRIGRKTFYRRAAIQEWIRAQEQAHPVRKTRGRS
>NZ_CP017781.1|WP_156894334.1|1445852_1446017_+|hypothetical-protein
MKVEPHGIAVADSLCGCVDSWLSSPKESKKENRQTLCPNGRSAGLQAISLDDAL
>NZ_CP017781.1|WP_071165946.1|1446113_1446716_+|hypothetical-protein
MPLPPVAFFSIYEIAVRWGCPPADVAGWAAAGHLHVVAGIPPVLCGDETVAGMVRVPMAELMGMFRRMGPSDDQARLKRVMPLGSKTWLKITDPAEGLLVRSSDLLLDSGTLQAFEEERDLLRRPASTIGASPRYDWDAMYAWLTWFLFEKGVPDTQTALVTLVQDWFVQNSKSGEVPDESTIRKRLSSLWRRLRGEDAA
>NZ_CP017781.1|WP_071165947.1|1446719_1447991_-|site-specific-integrase
MFKRLKLNEKTLREAEPKPGVSYQIFDTEVIGFAARVQASGARTFTIDYRHAGRQRRMTIGRWPEWSVTAARERAKELRRAIDEGQDPLAARDGWRGAPRITDMIDRYIAEHLPKLAKTNAGDQVSMLKKMVEPAWGNRLVTEITKSDVAKFLDFVAEGRPRPCKAKPNNRARKLQGQKPTPIRANRMGEVLRKMFTLAVEWEWRADNPAQGFHRRIEHARERFLSPEELTRLAAVLDEAEDQRAAAIIRMCMLTGARVGEVRTARFEQFNLDYAIWSKPASTTKQRKIHRVPISQDVAAIVRLRQQAVPSGNPWLFPGDTIGQPVREIRRFWAKVQKDAGLADVRIHDLRHTFASLLVSGGASLEMIGKLLGHSQVQTTQRYAHLMDSPLRAGVDTVASLLRPRPRLVHDAAQDQADLPKSA
>NZ_CP017781.1|WP_156894335.1|1448342_1450040_+|hypothetical-protein
MKPNEVHYAVAEQGFFGALLMLSRSDRRDEELIRRFAEAASSRNALISEQDMEVLHRVSGTNFFTLQILICEVIPLLQSAPSEVMGLVELLVEKGGEDLAANQPNAAFRKWCGSDSRRANDVIGSARDGNALALRHLVFALEAKCDVQEAFRSAEANGAERTAGVLALSRMLLSQEEAERALAHILKLVDATEADEGAGFLTAAIDIAAKHPGLDRSELAKSLDQISESNTPLAVHFMATALHGHSKEMTDSEVQSCLRGILLVDPKNKGTVREIDWALAQLWDSDPVRAGHAAKTLIAHSEGEIGSEELNSFFAAIENGDRRQLARLATDWLMGGEFHVCSALTSLFSEINRSTPCVDVFPEDLPLNAIDQIFLCRKAIGYLFISPMTAASWCVAALRRNDAAAASEVADLLFDPLLLNYGGALKDWLEEVVKADAPGADAIASALKRAESVWQGAEAARVVVELIPPTSHRALVRFQEAEEAYQIQVRAREKSIFAQLVTTQTLLYGDQSSFSRRDRDGNRSTQVVKMAEISVSSELPKGIIFDPIGTEWLLETFRHEQRAVG
>NZ_CP017781.1|WP_071165950.1|1450036_1451731_+|hypothetical-protein
MKLLVRQHLQGMKERGELDVLLPQLLSELGYEIVHHPRVGGRQAGVDVAAVGPDPDADGTRSILLFVIKSGDVGRADWDGTLQAVRPSLGEVLDDYIPNRLPHQYRDLPVAICVCMGGEIQEGIRAQWRGFVERQSTEMLNFREWNGDRLANLILSGILGKELLDPDHRSHFQKAIALVSEPEESYRNFRALLDALAENIGNDQRGTTHLRQMMICLWVLVGNGLDADNFEAPYRACELAVLHAWDALRRCPESAKSRHAERKEILDHVLSLYFKVGQKFMLEKIGPHAAQQHALSAAVRSRSALDVNLALFETMGRAALLGLWHHYIGCSTEGERQREHLKTRNRLLDLAISMVNVNPTLLAPMRDDHHIEIGLLMLLAQGCGRLQHVDHYLREVANRLLFRYVRRSHWVTHYTDYRQLARHPLDLGDEYFQQSTCGSVLVPFMLAGLERLGASEELSALLEVVSGELPHMTQQVWVPSDQTDDCIWRSGETIGFGIPLATRDSDGIGVSLSAEIDAIVSEQQQINQMKAVQHGLVPLLMTACRHHRIPLPPHFWFQPIGKSV
>NZ_CP017781.1|WP_156894336.1|1452253_1453011_+|IS5-family-transposase
MSDLFWLTDAQMARLEPFFPKSHGRPRVDDRRVLSGIIFINRNGLRWRDAPIAYGPHKTLYNRWKRWSDKGIFARMMAGLAAEHSETKTVMIDATYLRAHRTATSLGGEKGGRGRLIGRTKGGMNTKLHAICDSQGRPLNLFATAGQVSDYIGARALLSSLPKVDWLLGDRGYDADWFREALKDKGIRACIPGRKQRKKAVKYDKRRYKRRNRIEIMFGRLKDWRRVATRYDRCPKVFLSAIALAATVIYWL
>NZ_CP017781.1|WP_068765065.1|1453045_1453231_+|hypothetical-protein
MAELGYVGSADYVEMWKQSVRVEKAQYPALVGVAYFNQREVYPWPENFGAPDWRMKNQILK

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Crispr_ID: NZ_CP017781_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017781_3

2295724-2295785

Orphan

Consensus_repeat	Method
GCCCTCCTCCTCCTTCCTGAGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017781_3

>merge|NZ_CP017781|3|2295724-2295785|CRISPRCasFinder
GCCCTCCTCCTCCTTCCTGAGGGCGCCGTCACAAATACCGGGCCCCTCCTCCTCCCTGGGCC

>NZ_CP017781|3|3|2295724-2295785|CRISPRCasFinder
GCCCTCCTCCTCCTTCCTGAGGG	CGCCGTCACAAATACC
GGGCCCCTCCTCCTCCCTGGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017781.1\|WP_071166425.1\|2302244_2303339_-\|GTP-cyclohydrolase-I-FolE2	unknown	unknown	gnl\|CDD\|237466
NZ_CP017781.1\|WP_071166426.1\|2305465_2306365_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|274527
NZ_CP017781.1\|WP_068766606.1\|2284735_2285350_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017781.1\|WP_068766589.1\|2306979_2308017_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP017781.1\|WP_071166421.1\|2291694_2292726_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl\|CDD\|234597
NZ_CP017781.1\|WP_071166424.1\|2299687_2302147_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|273429
NZ_CP017781.1\|WP_068766592.1\|2304846_2305464_-\|septation-protein-IspZ	unknown	unknown	gnl\|CDD\|367894
NZ_CP017781.1\|WP_068766601.1\|2291320_2291698_-\|cell-division-protein-FtsL	unknown	unknown	gnl\|CDD\|227749
NZ_CP017781.1\|WP_071167228.1\|2297039_2298509_+\|acetyl-CoA-hydrolase/transferase-family-protein	unknown	unknown	gnl\|CDD\|274588
NZ_CP017781.1\|WP_068766598.1\|2293919_2294984_-\|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455
NZ_CP017781.1\|WP_083392669.1\|2292725_2293328_-\|division/cell-wall-cluster-transcriptional-repressor-MraZ	unknown	unknown	gnl\|CDD\|234728
NZ_CP017781.1\|WP_068766605.1\|2285369_2286452_-\|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl\|CDD\|234638
NZ_CP017781.1\|WP_071166420.1\|2289536_2291324_-\|penicillin-binding-protein-2	unknown	unknown	gnl\|CDD\|223839
NZ_CP017781.1\|WP_071166419.1\|2286456_2287917_-\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	unknown	unknown	gnl\|CDD\|184501
NZ_CP017781.1\|WP_068766754.1\|2295995_2296793_+\|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ	unknown	unknown	gnl\|CDD\|225509
NZ_CP017781.1\|WP_068766590.1\|2306391_2306976_+\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
NZ_CP017781.1\|WP_068766603.1\|2287916_2289401_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|234660
NZ_CP017781.1\|WP_068766593.1\|2303405_2304584_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|168979
NZ_CP017781.1\|WP_068766597.1\|2295238_2295442_+\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|368980
NZ_CP017781.1\|WP_071166423.1\|2298568_2299684_+\|Hint-domain-containing-protein	unknown	unknown	gnl\|CDD\|372590

Protein	Function_ID	Function_description	E-value
NZ_CP017781.1\|WP_071166425.1\|2302244_2303339_-\|GTP-cyclohydrolase-I-FolE2	gnl\|CDD\|237466	PRK13674, PRK13674, GTP cyclohydrolase I FolE2.	6.31159e-120
NZ_CP017781.1\|WP_071166426.1\|2305465_2306365_-\|EamA-family-transporter	gnl\|CDD\|274527	TIGR03340, phn_DUF6, phosphonate utilization associated putative membrane protein. This family of hydrophobic proteins has some homology to families of integral membrane proteins such as (pfam00892) and may be a permease. It occurs in the vicinity of various types of operons for the catabolism of phosphonates in Vibrio, Pseudomonas, Polaromonas and Thiomicrospira.	6.34214e-18
NZ_CP017781.1\|WP_071166423.1\|2298568_2299684_+\|Hint-domain-containing-protein	gnl\|CDD\|372590	pfam13403, Hint_2, Hint domain. This domain is found in inteins.	3.29462e-41
NZ_CP017781.1\|WP_071166421.1\|2291694_2292726_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl\|CDD\|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	2.36669e-157
NZ_CP017781.1\|WP_071166424.1\|2299687_2302147_-\|AAA-family-ATPase	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP017781.1\|WP_068766592.1\|2304846_2305464_-\|septation-protein-IspZ	gnl\|CDD\|367894	pfam04279, IspA, Intracellular septation protein A.	1.12096e-62
NZ_CP017781.1\|WP_068766601.1\|2291320_2291698_-\|cell-division-protein-FtsL	gnl\|CDD\|227749	COG5462, COG5462, Predicted secreted (periplasmic) protein [Function unknown].	1.33551e-08
NZ_CP017781.1\|WP_071167228.1\|2297039_2298509_+\|acetyl-CoA-hydrolase/transferase-family-protein	gnl\|CDD\|274588	TIGR03458, Propionyl-CoA:succinate_CoA_transferase, succinate CoA transferase. This family of CoA transferases includes enzymes catalyzing at least two related but distinct activities. The E. coli YgfH protein has been characterized as a propionyl-CoA:succinate CoA transferase where it appears to be involved in a pathway for the decarboxylation of succinate to propionate. The Clostridium kluyveri CAT1 protein has been characterized as a acetyl-CoA:succinate CoA transferase and is believed to be involved in anaerobic succinate degradation. The propionate:succinate transferase activity has been reported in the propionic acid fermentation of propionibacterium species, where it is distinct from the coupled activities of distinct nucleotide-triphosphate dependent succinate and propionate/acetate CoA transferases (as inferred from activity in the absence of NTPs). The family represented by this model includes a member from Propionibacterium acnes KPA171202 which is likely to be responsible for this activity. A closely related clade not included in this family are the Ach1p proteins of fungi which are acetyl-CoA hydrolases. This name has been applied to many of the proteins represented by this model, possibly erroneously.	0
NZ_CP017781.1\|WP_068766598.1\|2293919_2294984_-\|Mrp/NBP35-family-ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	1.17749e-138
NZ_CP017781.1\|WP_083392669.1\|2292725_2293328_-\|division/cell-wall-cluster-transcriptional-repressor-MraZ	gnl\|CDD\|234728	PRK00326, PRK00326, transcriptional regulator MraZ.	1.2666e-33
NZ_CP017781.1\|WP_068766605.1\|2285369_2286452_-\|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl\|CDD\|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	0
NZ_CP017781.1\|WP_071166420.1\|2289536_2291324_-\|penicillin-binding-protein-2	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	9.95941e-123
NZ_CP017781.1\|WP_071166419.1\|2286456_2287917_-\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	gnl\|CDD\|184501	PRK14093, PRK14093, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional.	3.42309e-139
NZ_CP017781.1\|WP_068766754.1\|2295995_2296793_+\|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ	gnl\|CDD\|225509	COG2961, ComJ, Protein involved in catabolism of external DNA [General function prediction only].	1.43268e-69
NZ_CP017781.1\|WP_068766590.1\|2306391_2306976_+\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	4.21483e-43
NZ_CP017781.1\|WP_068766603.1\|2287916_2289401_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl\|CDD\|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
NZ_CP017781.1\|WP_068766593.1\|2303405_2304584_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|168979	PRK07504, PRK07504, O-succinylhomoserine sulfhydrylase; Reviewed.	0
NZ_CP017781.1\|WP_068766597.1\|2295238_2295442_+\|DUF1127-domain-containing-protein	gnl\|CDD\|368980	pfam06568, DUF1127, Domain of unknown function (DUF1127). This family is found in several hypothetical bacterial proteins. In some cases it represents it represents the C-terminal region whereas in others it represents the whole sequence.	2.43104e-08
NZ_CP017781.1\|WP_068766589.1\|2306979_2308017_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	1.16578e-171

>NZ_CP017781.1|WP_068766597.1|2295238_2295442_+|DUF1127-domain-containing-protein
MALVQELHGNDAGFTRFFAGLSEALARRKVYRQTLRELKALSARELADLGIHRSMITRVAQEAAYGK
>NZ_CP017781.1|WP_068766598.1|2293919_2294984_-|Mrp/NBP35-family-ATP-binding-protein
MSLSKESVLEALRIVRMPGGGDPVSRDLIRALAVESGVVRFVLEGAPEAELAAAKPAIEAAVRALAGVESLTVVVPSGPAKGMGAGPKIGQHPTPQAGPQGVAGVRHIIAVGSGKGGVGKSTVSSNLAVALARAGKRVGLLDADIYGPSQPRMMGVQQRPASPDGKTILPLRAHGVTLMSIGLMLKEDEAVIWRGPMLMGALQQMLGQVAWDHYGPLDVLIIDLPPGTGDIQLTLCQKTRLDGAIVVSTPQDVALLDARKALDMFRRLETPVIGLIENMSSYVCPNCGHEAHLFGHGGVGAEAVKLGLPYLGELPLDLEVRLAGDAGTPVAAGEGPAAAGYRAIAEKLIAAGAV
>NZ_CP017781.1|WP_083392669.1|2292725_2293328_-|division/cell-wall-cluster-transcriptional-repressor-MraZ
MGRGRRIGQWQQSDPPFSISGIDATGWDRRAPALARRFRGSETFKVDAKGRVSIPASFRRVIEAGDPDWAPGARPQIVIVYGGAERKYLEVFTMEAIYEIDEQIDAMQRGSGERAEIEELMYAQSHQTDIDGDGRLVLPQKLREKIALKGEAFFASAGTSFKIWDPETYEAEQAAIAAARAEARPEGYDPLVHLPKIGAA
>NZ_CP017781.1|WP_071166421.1|2291694_2292726_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MSDAERPHIPVLLRPLLEAVAPVSGVWLDGTFGAGGYARGLLAAGAGRVIGVDRDPSVFAMAEGWRGDYGDRLVLVEGTFSELDTYAAEIAPGEGGFGGLDGVVLDLGVSSMQLDQAERGFSFMTDGPLDMRMSRSGPSAADLVNELSEEELADILYHYGEERASRRIARAIAEARRASPFETTRQLVAVIERCLPRPKPGQSHPATRSFQAIRIAVNDEFGQLIEGLEAAERALKPGGRLAVVTFHSLEDRVVKRFFQARSGRAAHVNRYAAAPAEEAPAPFDLLTRKSIGPDPEELADNPRARSAKLRVARRTSAPAGRAERAGLGLPAPVLTPSPRGKSR
>NZ_CP017781.1|WP_068766601.1|2291320_2291698_-|cell-division-protein-FtsL
MRNLLYLATALCVMGLAFWAYRVNYDTQDRQGELRALNREIASLHEGLGVLNAEWAYLNRPERLTELVNLNFERLALLPLAPEQFGAVGQVAYPAPPEAAPLGEGGLVDPIDVIARNGASDGGPL
>NZ_CP017781.1|WP_071166420.1|2289536_2291324_-|penicillin-binding-protein-2
MIRTPLRPLARILQARAKGENPDAIERENIRLRGEETRDRARLRAEGRLLMMGLMFLGAFVAVGLRMGSLAATPPQEPQLSGGAEAIVAQRADITDRAGRVLATNLVTHALYAQPPMLVDPERTADKLVKIFPDLERDRLVKDFTGTRKFVWIKKKISPEQMQAVHDIGDPGLLFGPREMRLYPNGRLAAHILGGARFGAEGVSSAEILGVAGVEKAFDGWLRDPANHGAPLALSLDLTIQSAVEEILDGGMKLMNAKGAAAILMDVRSGEILAMASLPDFDPNDRPAPLAKGDASDSPLFNRAVQGVYELGSTFKIFAVAQAMQLGLVNPATMVPTKSPMVWGRFRIRDFHNYGAENSVTDIIVKSSNVGTARIVQMIGADRQRDFLRKMGFLEPTSVELVEAPTGRPIVPAKWSEISSMTIGYGHGLSASPLHLAAAYATIANGGRRVMPTLVHGKTAAPGEQVMDPIVARRALAMMRAVVARGTASFGEVAGYQVAGKTGSADKAKPSGGYYDDKVIATFASVFPVTDPKYVLVLTLDEPSENSGSEPRRTAGWTAVPVAAEVIRRVAPLLGLRPEAGPDEMEGIQLVKKDG
>NZ_CP017781.1|WP_068766603.1|2287916_2289401_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MDIDPKPLSALGLTVPNGPDVVISGISVDSRRVQPRHLFAALPGVAAHGAAFVAAAVERGAVAVLTDRAGGEILRAELAGGPVALIVVEDPRQALAFAAALFYGAQPATMIAVTGTNGKTSVASFTRQIWQLMGLEAANIGTTGVEGAFTAPSAHTTPEPVTLHRLLAEMAAAGVTHAAMEASSHGLAQRRLDGVRLAAAAFTNFTQDHLDYHATFEEYFAAKAGLFTRVLPEEGVAVLNTDDPKGEVLAAYATARGQRVIRVGHAEGCEMRLMGQRYDATGQDLRFAWGGAAHLVRLPLIGGFQAMNVLTAAALVIACGADPAEVFATLPRLSTVRGRMQLAATRENGATVFVDYAHTPDAVETAIRALRPHVMGHLVAIVGAGGDRDRTKRPLMGRAAAETADRVIVTDDNPRTEDPATIRAAVMAGAGPEATEVGDRAEAILRGVDMLGPGDALLICGKGHESGQVIGTDIYPFDDVEQASVAVAALDGKI
>NZ_CP017781.1|WP_071166419.1|2286456_2287917_-|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase
MAVLWTSAEAVAATGGRATRDFAAMGISIDTRSLRPGDLFVALKDVRDGHDFVAQALAAGAAAALVSRLPEGCSEADPLLIVEDVLPALEALGRAGRARTRARVIAVTGSVGKTSTKEMLRAVLAAQGRVHAAEASFNNHWGVPITLARMPAEADFAVIEIGMNHPGEIAPLARLARPHAAMITTVAAAHLEAFAEAEGGGLAGIAREKAAIFEGLEPGGVAVVPTGLEVSAILEAAAAARADRVIRFGPAEGSDYRLVSATIAGDATIVRADHAGQELLFKVLSPGKHFANNALGVLALAEAVGADVAVAACDLGLWEPPAGRGARERVWLDIVDESQSFDLFDDAFNANPASMTAGLEVLAGAAPRDGVGRVKQGRRVAILGDMLELGPDEAALHAAIADDPSMAAIDTVHLAGPRMRALYEALPRAKRGEWFATAKELAERARHLVDAGDVVLVKGSKGSKVSLVVDALKKLGQPGAAESFKG
>NZ_CP017781.1|WP_068766605.1|2285369_2286452_-|phospho-N-acetylmuramoyl-pentapeptide--transferase
MLYWLAHLSDGGDLFNLFRYITFRAGAAFFTALIFGFLFGRPLIDILRRKQGKGQPIRTDGPQSHFAKAGTPTMGGLLILSAMLVSTLLWARLDNGYIWIVLGVTYGYALIGFADDYAKVTKQNVKGVSSRTRMVLGLLLAGLAAVAAAWLHPADLSNRLALPIFKDVLINLSWFYVPFAMVVIVGAANAVNLTDGLDGLAIMPAMIAAGTLGAIAYVVGRADFTTYLGVHFVPGTGEIFVFTAALIGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHELVLAIVGGLFVVEALSVIIQVAYFKRTGKRVFLMAPIHHHFEKKGWAEPQIVIRFWIISLILALIGLATLKLR
>NZ_CP017781.1|WP_068766606.1|2284735_2285350_-|hypothetical-protein
MLLALVPLVFGVMVLLTARRMGGARRTEAARRAGRGAHAEALRAGDFAAAAALAETHYGPQSAELATALLALSETAPPEEALPALRRALAILSARQAPPETRAAPLARLAALSPDADEAYAAITQSLAQTRRAFGKSAPEFAARTAQAARLFAAQGRAPEAEAQFRAALALATGPEAVTLRADFATFLAARGRTREAEVLRAAP
>NZ_CP017781.1|WP_068766754.1|2295995_2296793_+|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ
MLSYQHGFHAGNLADVHKHALMATALDYLTRKDKPLSYLETHSGRGLYALDSAAAVKTGEAAEGIERVEKLGWFGAAHPYARALKAVRARHGPRAYPGSPMLAAELLRPIDALQLCELHPQEFAALREAMAPHGGIFHHKDGLAMALALTPPTPRRGIMLIDPSWEVKADYETIPKLLGQVARKWNVGILALWYPILASEVAASAAQRKMVRSLRDAHPEALISEVGFPPAREGHGMIGSGMVFLNPPWGLEGEARRLEGLFRRL
>NZ_CP017781.1|WP_071167228.1|2297039_2298509_+|acetyl-CoA-hydrolase/transferase-family-protein
MTAEEAARLIPSGAAIGMSGFTGSGYPKAVPQALAARIEDEHAKGNRFKVSIWSGASTGPELDGALAKADGIDFRLPYNSDPIARQKINAGTMQYFDMHLSQVAPMAWQGFLGKLDWAVVEVSGITPDGHLIPSSSVGNNKTWLDIAENVILEVNAWQSEHLLGMHDIYYGTALPPNRVPIPLIRPDQRIGEPTFRIDPAKVVGVVMTDSPDRNAPFAKPDAVAYAIAGQLLEFFEHEVKVGRLPRNLLPLQSGVGNVTNAVLSGLMHGPFDQMTSFTEVVQDGMIEMLETGKLLMASATAFSLSPEMAHRINAEAERFRGKLVLRPQEISNHPELIRRLGCIAMNGLIEADIYGNVNSTHVMGSRIQNGIGGSGDFARNAFLSIFMTPSTAKGGAISAIVPMVAHTDHIAQDVHVIVTEQGLADLRGLSPKARAKLVIERCAHPDYRPMLQDYYDRASRSSYGLHAPNILPEALSWHQRFVETGSMKP
>NZ_CP017781.1|WP_071166423.1|2298568_2299684_+|Hint-domain-containing-protein
MSLTIYALDYQFAAATDGNVNSGAGTSTFDYPPNSTKNLVISSQDGDPSPYTFDVGDTYTVSFTGNGGTTIENATVIRTDPISINDDQGWAVVFEGLDSKGDLTQVIWTPEFDLENWYWTNYGPSNPPGFYTTDASATNYAVPCFTAETPIETERGPRPAGEIGVGDLVHTLDRGPQPVLWAARHEMRGQRAGAPVWFERGAIGNDTPIELSQHHRVLLRGAALIEPYGDNEALAPALSFLNGATIRLRPRARVTYVHLMCAHHEVIRAGGAFVESLFAGPEAMALFARLGDAPPLDLARRQIRPARPLLTRRQGEEMRAAILRETRVKRAMFGRRLPLRNAPKFTLRRAPGPGLPAFARLVETETAPQEG
>NZ_CP017781.1|WP_071166424.1|2299687_2302147_-|AAA-family-ATPase
MNGFDDAYEGALSLSARAMMAARGGEPGYLEGLNAAQREAVETLDGPVLMLAGAGTGKTKALTTRIAHLIHTGRARPNEILAVTFTNKAAREMKERVGRLLGGAIEGVPWLGTFHSVCVKLLRRHAELVGLKANFTILDTDDQVRLLKQLILAANMDEKRWPARQLAGLIDGWKNRALTPERVRGAETAAFNNRGSELYAAYQERLVTLNAVDFGDLLLHMVTIFQTHADVLAQYQRWFRYILVDEYQDTNVAQYLWLRLLAQGHRNICCVGDDDQSIYGWRGAEVGNILRFEKDFPGAAVIRLEQNYRSTEHILAAASRLISGNEGRLGKTLWTEARGGEKVRLIGHWDGEEEARWIGEEIEALAAGRRALGPVRLSDQAILVRASHQMRAFEDRFLSIGLPYRVIGGPRFYERLEIRDAMAYFRLAVSPEDDLAFERVINTPKRGLGDKAQARIQSLARETGVGLLEAARLMVAEGELSGKAGGQLRQFVEAVDRWHAEIRAASPATAVTAAEDDELLIEPEEGGIAPANDHSHVRLAERILEESGYVEMWLNDKTPEAPGRLENLKELVKALEQFDNLQGFLEHVALIMDNDRDESGDKVSIMTLHGAKGLEFPVVFLPGWEDGLFPSQRAMDETGQKGLEEERRLGYVGITRAERLCTISFAGNRRVYGQWQSQLPSRFIDELPAADVEVLTPPGLYGGGFGAAGAYGGAGAGFSGGSRLEERAGRADVYNSPGWKRLQAQGGQSAAPARRGAQVFDADAEDFEIGERVFHKKFGYGRVVATEGDKLVVDFEKAGEKKLLASFVVPAAQAGEVPF
>NZ_CP017781.1|WP_071166425.1|2302244_2303339_-|GTP-cyclohydrolase-I-FolE2
MTIHDRIGAPEREAAEQALATLRAWAAQADPAEVARLDPAIARLLPGRETGNYPDLRRAYDPEFRADAAYKAGLPDLQNGPSSLIVGARTRIEHVGISHFRLPIRYQLRAGGEIALETSVTGTVSLEAEKKGINMSRIMRSFYAHAESAFSGAVMARAVDDYKDHLESFDARLSMRFSFPSRVESLRSGLAGWQYYDIALEQIDRAGARKRVIHLDYVYSSTCPCSLELSEHARQVRGQLATPHSQRSVARISVVAQPGARLWFEDLIEIARAAVPTETQVMVKREDEQAFAELNAANPIFVEDAVRAFAAGLLADPRVGDFRVMASHQESLHSHDAVALLTEGETFASDSLDPRLFASLHHPG
>NZ_CP017781.1|WP_068766593.1|2303405_2304584_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MSTDWNTRTKLVHEGIRRSQYGEMAEALFLTQGFVYPSAEAAEARFIGAGEDEFIYARYGNPTTRMFEDRIAAIEGTEDAFACASGMAAINGALTSQLKAGDHVVAARQMFGSCLHVLKVLSGFGVGVTLVDGTKLYEWRAAMRPETKICFFESVSNPGLEVIDIAGVAEIAHAGGAVVVVDNVFASPIFSKAVAQGADIVVYSTTKHIDGGGRALGGVVCGTRAFIRGPLETYVKHTGGAMSPFHAWIMLSGMQTLDLRVRAQAANAAMAASAVAGHAALARTIYPGLIDHPQHALAMAQMGSGGTMLCLDLAGGKEAAFRFLNALKIVSISNNLGDAKSIATHPATTTHKNLSEEDRAVIGITPGLVRISLGIEDGADLVADLRQALDAV
>NZ_CP017781.1|WP_068766592.1|2304846_2305464_-|septation-protein-IspZ
MAGKKINPWLKAGLEFGPLVAFFAAFVRLKGESFVIHGVSYSGFVVATALFVPLMVITTGVLWRLTGRLAPMQVATLVLVVVFGGLSIWFNDPKFFKMKPTLIYLLFAGLLGFGLLRGKPWLQLVMEEALPMRHEGWMILTKRLALFFLGLAVANEVIWRTMSDQAWVNFKTFGLTAAMFAFFIAQGGLIQRYGIEKPKDGGPEA
>NZ_CP017781.1|WP_071166426.1|2305465_2306365_-|EamA-family-transporter
MGELITALAGTPAGHQAALGLALAAAFLHALFGALQKGRHDPWLSRAAIDASYGLIAAPVALFVVPWPEPHMWPIFAGVWAIHAGYKIAQAACYQRGAYTVVYPVVRGTGPLFTVAGAEVIFGEHFTAGQWAGVAVLLAGIYGLALYNLRTVREGRETMGAALGLAVLTGAFVAAYTTFDAYGIRATADPFTFLAWFFFLDGWLMPLLTVRRWRHVPSSELGPLLKRGVIGAFVAYFSFGAIMLATRLDRVGEAAVLRETSTVFAALIGWLVLGEKVGPRRVALMALIAAGAVIVEMAG
>NZ_CP017781.1|WP_068766590.1|2306391_2306976_+|MgtC/SapB-family-protein
MSFLDPLWSDLAASFTATPAPVATLRLVAAMVMGGLIGFEREWHHKPAGLRTHMLISVAAALFALLSFELLEISRQLGGAETGARNDILRLIGAVTSGVAFLAAGTIVVNAGRVKGLTTGAGMWLAGAVGLACGTGRIGLAGLAAGLTVVVLWLFRRLEDAVEHKAAREAAEEAAARAEAGLLARARHPGSEAE
>NZ_CP017781.1|WP_068766589.1|2306979_2308017_-|signal-recognition-particle-docking-protein-FtsY
MSFFNKLKSRLTRSSTKLEEGLEAIVSEGGAVEAAPESAPESLPAPEAGKKPGFFGRLIGRGGEEAAPRRVLDDEMLESLEELLIASDMGVETALRVSANIAEGRMGKRLSVPEIKGLLADEVARIMGPVARPLPIYPKRPQVVLVVGVNGSGKTTTIGKLASQFKAAGKSVVIAAGDTFRAAAVEQLKVWGERAGVPVLTAPEGSDPASLAFDAMTKAEAEGADLLMIDTAGRLQNRADLMEELAKIVRVIRKKDPSAPHNTLLVLDATTGQNALSQVEIFSKIADVSGLVMTKLDGTAKGGVLVALADRFGLPIHAIGVGEQIDDLAPFDPEEFARALVGAER

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017781_2	2.1\|1444150\|23\|NZ_CP017781\|CRISPRCasFinder	1444150-1444172	23	NC_009427	Novosphingobium aromaticivorans DSM 12444 plasmid pNL2, complete sequence	207913-207935	3	0.87

1. spacer 2.1|1444150|23|NZ_CP017781|CRISPRCasFinder matches to NC_009427 (Novosphingobium aromaticivorans DSM 12444 plasmid pNL2, complete sequence) position: , mismatch: 3, identity: 0.87

tttcggcattttccggacacggg	CRISPR spacer
tttcggcattttccggacaccat	Protospacer
******************** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1405321 : 1447991

Acidithiobacillus_phage(25.0%)

tail,capsid,head,portal,integrase,terminase

attL 1400376:1400425|attR 1451996:1452045

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1400376:1400425	attL	NA	NA	NA	NA
WP_071165916.1\|1405321_1405996_-	DUF882 domain-containing protein	A0A0K1LLY2	Rhodobacter_phage	4.0e-43	45.5
WP_068767754.1\|1406068_1406377_-	hypothetical protein	NA	NA	NA	NA
WP_071165917.1\|1406410_1408333_-	DUF2793 domain-containing protein	A0A0K1LM04	Rhodobacter_phage	1.4e-29	28.6
WP_071165918.1\|1408354_1412353_-	hypothetical protein	A0A0B5A7K5	Paracoccus_phage	3.5e-264	42.2
WP_071165919.1\|1412362_1412797_-	peptidase	A0A1V0DYB6	Dinoroseobacter_phage	2.1e-29	45.2
WP_071165920.1\|1412793_1413678_-	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	1.7e-62	44.9
WP_071165921.1\|1413674_1414301_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	4.8e-59	55.3
WP_071165922.1\|1414300_1416757_-\|tail	phage tail tape-measure protein	A0A0U4JEA4	Pseudomonas_phage	3.6e-49	51.5
WP_071165923.1\|1416979_1417417_-	hypothetical protein	NA	NA	NA	NA
WP_071165924.1\|1417419_1418358_-	hypothetical protein	G8DH51	Emiliania_huxleyi_virus	5.6e-96	57.0
WP_071165925.1\|1418381_1418804_-	acyl-CoA transferase	G8DH50	Emiliania_huxleyi_virus	1.0e-33	51.4
WP_156894332.1\|1418977_1419421_-	hypothetical protein	NA	NA	NA	NA
WP_156894333.1\|1419436_1420285_-	hypothetical protein	NA	NA	NA	NA
WP_071165926.1\|1420404_1421025_-	hypothetical protein	G8DH49	Emiliania_huxleyi_virus	6.2e-51	51.5
WP_071165927.1\|1421029_1421344_-	hypothetical protein	NA	NA	NA	NA
WP_071165928.1\|1421355_1422381_-\|capsid	major capsid protein	K4I3Z3	Acidithiobacillus_phage	2.9e-101	55.0
WP_071165929.1\|1422429_1422810_-\|head	head decoration protein	K4ICP8	Acidithiobacillus_phage	1.3e-22	50.4
WP_071167160.1\|1422863_1424174_-	S49 family peptidase	A0A068CE01	Rhizobium_phage	3.0e-63	45.8
WP_071165930.1\|1424173_1425685_-\|portal	phage portal protein	K4I1F2	Acidithiobacillus_phage	1.6e-172	66.7
WP_071165931.1\|1425687_1425900_-	hypothetical protein	K4HZB1	Acidithiobacillus_phage	1.3e-05	42.9
WP_071165932.1\|1425899_1427948_-\|terminase	phage terminase large subunit family protein	A0A2H4JIC6	uncultured_Caudovirales_phage	1.0e-206	56.6
WP_071165933.1\|1427895_1428432_-	hypothetical protein	NA	NA	NA	NA
WP_071165934.1\|1428566_1428782_+	hypothetical protein	NA	NA	NA	NA
WP_071167161.1\|1428893_1429121_+	hypothetical protein	NA	NA	NA	NA
WP_071165935.1\|1429216_1429780_+	DUF3489 domain-containing protein	K4HZZ2	Acidithiobacillus_phage	5.5e-14	35.3
WP_083392612.1\|1429889_1430402_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_071165936.1\|1430432_1431761_-	site-specific DNA-methyltransferase	K4I3Y2	Acidithiobacillus_phage	1.5e-131	55.8
WP_071165937.1\|1431757_1433020_-	DNA methylase	A0A0A8ILE7	Aurantimonas_phage	5.0e-124	55.5
WP_071165938.1\|1433420_1435490_-	AIPR family protein	NA	NA	NA	NA
WP_071165939.1\|1435486_1436461_-	PD-(D/E)XK motif protein	NA	NA	NA	NA
WP_071165940.1\|1436447_1439183_-	Z1 domain-containing protein	NA	NA	NA	NA
WP_071165941.1\|1439179_1440673_-	ATP-binding protein	NA	NA	NA	NA
WP_156894434.1\|1440756_1442310_-	DNA (cytosine-5-)-methyltransferase	G3CB01	Aeropyrum_pernix_spindle-shaped_virus	3.5e-18	28.7
WP_071167163.1\|1442377_1442881_+	DNA mismatch endonuclease Vsr	E5E3X5	Burkholderia_phage	2.1e-36	48.3
WP_071165942.1\|1442939_1443617_-	hypothetical protein	G8DGC1	Emiliania_huxleyi_virus	1.4e-32	38.4
WP_071165943.1\|1443613_1444621_-	helix-turn-helix domain-containing protein	A0A068CE61	Rhizobium_phage	6.2e-16	48.4
WP_071165944.1\|1444617_1445013_-	VRR-NUC domain-containing protein	NA	NA	NA	NA
WP_071165945.1\|1445009_1445249_-	hypothetical protein	NA	NA	NA	NA
WP_071167164.1\|1445245_1445494_-	DNA-binding protein	NA	NA	NA	NA
WP_156894334.1\|1445852_1446017_+	hypothetical protein	NA	NA	NA	NA
WP_071165946.1\|1446113_1446716_+	hypothetical protein	NA	NA	NA	NA
WP_071165947.1\|1446719_1447991_-\|integrase	site-specific integrase	A0A221SAN4	Ralstonia_phage	2.2e-34	30.7
1451996:1452045	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1608366 : 1620726

Paracoccus_phage(37.5%)

capsid,tail,head,portal,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071166048.1\|1608366_1609545_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	1.0e-62	39.9
WP_071166049.1\|1609546_1609780_+	hypothetical protein	NA	NA	NA	NA
WP_068765192.1\|1609790_1610348_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	8.7e-36	51.2
WP_068765193.1\|1610382_1611579_+\|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	1.2e-66	43.2
WP_071166050.1\|1611763_1612372_+	hypothetical protein	NA	NA	NA	NA
WP_071166051.1\|1612702_1613110_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_068765197.1\|1613197_1613611_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_068765198.1\|1613619_1613946_+	gene transfer agent family protein	NA	NA	NA	NA
WP_071166052.1\|1613942_1614173_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_068765200.1\|1614176_1614839_+\|tail	phage tail tape measure protein	A0A1W6JP49	Morganella_phage	2.3e-11	35.4
WP_071166053.1\|1614848_1615481_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	7.5e-60	51.7
WP_068765202.1\|1615480_1616371_+	DUF2163 domain-containing protein	A0A1V0DY93	Dinoroseobacter_phage	1.5e-53	40.1
WP_071166054.1\|1616367_1616817_+	peptidase	F4YXU4	Roseobacter_phage	1.8e-31	50.7
WP_071166055.1\|1616817_1620726_+	host specificity protein	A0A0B5A7K5	Paracoccus_phage	2.5e-222	38.5

DBSCAN-SWA_3

1626792 : 1635748

uncultured_Mediterranean_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071166059.1\|1626792_1627686_-	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	5.2e-06	24.4
WP_068765214.1\|1629179_1629686_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	1.2e-44	58.8
WP_071166060.1\|1629678_1630293_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	7.3e-44	61.8
WP_071166061.1\|1630506_1631757_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	2.6e-64	37.4
WP_071166062.1\|1631816_1632926_+	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_071167179.1\|1633096_1633354_+	DUF2798 domain-containing protein	NA	NA	NA	NA
WP_071166063.1\|1633455_1633884_+	DUF4405 domain-containing protein	NA	NA	NA	NA
WP_071166064.1\|1633907_1634336_-	cupin domain-containing protein	A0A291ATU0	Pandoravirus	2.7e-29	48.6
WP_068765220.1\|1634473_1635748_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	6.2e-146	62.1

DBSCAN-SWA_4

1732671 : 1742033

Acidithiobacillus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071166124.1\|1732671_1733547_+	ATP-binding protein	K4HZX9	Acidithiobacillus_phage	3.4e-95	62.7
WP_071166125.1\|1733648_1734272_+	hypothetical protein	K4ICM8	Acidithiobacillus_phage	3.2e-55	57.8
WP_071166126.1\|1734286_1735975_+	DEAD/DEAH box helicase	A0A2D1GP10	Streptomyces_phage	1.6e-45	36.5
WP_071166127.1\|1736182_1736389_+	hypothetical protein	NA	NA	NA	NA
WP_071166128.1\|1736388_1737156_+	hypothetical protein	K4HZA0	Acidithiobacillus_phage	4.6e-72	54.0
WP_071166129.1\|1737107_1739468_+	AAA family ATPase	A0A1B2LRS1	Wolbachia_phage	5.2e-74	52.4
WP_071167188.1\|1739859_1740348_+	hypothetical protein	K4ICN3	Acidithiobacillus_phage	2.9e-51	62.4
WP_071166130.1\|1740344_1740545_+	hypothetical protein	NA	NA	NA	NA
WP_018303644.1\|1740537_1740918_+	hypothetical protein	NA	NA	NA	NA
WP_071165181.1\|1741268_1742033_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8

DBSCAN-SWA_5

3255011 : 3312045

Acidithiobacillus_phage(25.0%)

transposase,integrase,portal,terminase

attL 3247672:3247688|attR 3270870:3270886

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3247672:3247688	attL	NA	NA	NA	NA
WP_071166949.1\|3255011_3256166_+\|integrase	tyrosine-type recombinase/integrase	A0A221SAN4	Ralstonia_phage	2.7e-47	36.5
WP_071166950.1\|3256287_3257154_+	WYL domain-containing protein	NA	NA	NA	NA
WP_071166951.1\|3257224_3259615_+	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	1.9e-23	28.1
WP_156894400.1\|3259614_3260883_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_071166952.1\|3260892_3263913_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.2e-22	24.0
WP_156894284.1\|3264208_3265705_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_071165181.1\|3265701_3266466_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_083392711.1\|3266635_3267130_+	WYL domain-containing protein	NA	NA	NA	NA
WP_071166955.1\|3268407_3269433_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_071166956.1\|3269454_3270630_-	tetracycline efflux MFS transporter Tet(G)	NA	NA	NA	NA
WP_012112698.1\|3270936_3272292_-\|transposase	IS1380-like element ISPme1 family transposase	A0A1X9I6F6	Streptococcus_phage	3.8e-45	29.0
3270870:3270886	attR	NA	NA	NA	NA
WP_071166957.1\|3272368_3272725_-	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_083392702.1\|3272812_3274168_+\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	1.3e-45	29.7
WP_071166958.1\|3274390_3275434_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_071166959.1\|3275437_3276451_-	putative sulfate exporter family transporter	NA	NA	NA	NA
WP_071166960.1\|3276553_3278335_-	sulfoacetaldehyde acetyltransferase	NA	NA	NA	NA
WP_071166961.1\|3278361_3279759_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_071166962.1\|3279790_3280180_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_071166963.1\|3280197_3280689_-	universal stress protein	NA	NA	NA	NA
WP_071166964.1\|3280700_3282041_-	TRAP transporter large permease	NA	NA	NA	NA
WP_071166965.1\|3282040_3282577_-	TRAP transporter small permease	NA	NA	NA	NA
WP_156894449.1\|3282631_3283609_-	C4-dicarboxylate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_156894401.1\|3283764_3285243_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_083392713.1\|3285463_3285880_-	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_078527637.1\|3286348_3287704_+\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	5.0e-45	29.7
WP_028031186.1\|3288141_3288774_-	hypothetical protein	G8DH49	Emiliania_huxleyi_virus	6.3e-51	52.5
WP_028031185.1\|3288779_3289091_-	hypothetical protein	NA	NA	NA	NA
WP_071166966.1\|3289090_3289426_-	DUF2190 family protein	A0A088C4T4	Shewanella_sp._phage	9.6e-06	41.3
WP_071166967.1\|3289497_3289737_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_071166968.1\|3289742_3290030_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_071167293.1\|3290032_3292051_-	peptidase U37	A0A2I7S8L6	Vibrio_phage	8.7e-78	32.7
WP_071166969.1\|3292070_3293582_-\|portal	phage portal protein	Q75QM9	Wolbachia_phage	7.5e-82	38.6
WP_071167294.1\|3293581_3293791_-	hypothetical protein	NA	NA	NA	NA
WP_071166970.1\|3293790_3295794_-\|terminase	phage terminase large subunit family protein	A0A2H4JIC6	uncultured_Caudovirales_phage	1.9e-218	60.7
WP_071166971.1\|3295741_3296302_-	hypothetical protein	A0A2H4JCL4	uncultured_Caudovirales_phage	3.0e-28	44.8
WP_071166972.1\|3296415_3296640_+	hypothetical protein	NA	NA	NA	NA
WP_071166973.1\|3296737_3297256_+	DUF3489 domain-containing protein	K4HZZ2	Acidithiobacillus_phage	1.8e-11	38.2
WP_083392714.1\|3297307_3297682_-	HNH endonuclease	NA	NA	NA	NA
WP_071166974.1\|3297912_3298122_-	hypothetical protein	K4I1E3	Acidithiobacillus_phage	3.7e-16	63.8
WP_083392715.1\|3298131_3299229_-	DNA cytosine methyltransferase	A0A0F7L3T9	uncultured_marine_virus	9.4e-34	43.8
WP_071166977.1\|3299230_3300571_-	site-specific DNA-methyltransferase	A0A2H4JGF1	uncultured_Caudovirales_phage	2.1e-75	39.1
WP_068765055.1\|3300983_3301412_-	hypothetical protein	NA	NA	NA	NA
WP_071167295.1\|3301408_3301606_-	hypothetical protein	NA	NA	NA	NA
WP_071166978.1\|3301611_3302148_-	hypothetical protein	K4ICN3	Acidithiobacillus_phage	2.2e-52	65.3
WP_083392780.1\|3302615_3304928_-	AAA family ATPase	A0A1B2LRS1	Wolbachia_phage	1.8e-71	49.6
WP_071166980.1\|3304924_3305692_-	hypothetical protein	K4HZA0	Acidithiobacillus_phage	2.8e-77	57.5
WP_071167296.1\|3305691_3305892_-	hypothetical protein	NA	NA	NA	NA
WP_071166981.1\|3306104_3307796_-	DEAD/DEAH box helicase	G8EY40	Synechococcus_phage	2.2e-42	32.7
WP_071166982.1\|3307807_3308407_-	hypothetical protein	K4ICM8	Acidithiobacillus_phage	1.2e-51	61.9
WP_071166983.1\|3308426_3309296_-	ATP-binding protein	K4HZX9	Acidithiobacillus_phage	3.0e-99	61.3
WP_071166984.1\|3309292_3309781_-	hypothetical protein	NA	NA	NA	NA
WP_071166985.1\|3309807_3310170_-	hypothetical protein	NA	NA	NA	NA
WP_071166986.1\|3310169_3310373_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_156894402.1\|3310575_3311064_-	hypothetical protein	NA	NA	NA	NA
WP_071166988.1\|3311367_3312045_+	helix-turn-helix domain-containing protein	A0A0M3LPF9	Mannheimia_phage	1.1e-21	31.9

DBSCAN-SWA_6

3317922 : 3372428

Lactococcus_phage(25.0%)

transposase,integrase,protease

attL 3314117:3314132|attR 3339277:3339292

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3314117:3314132	attL	NA	NA	NA	NA
WP_068765715.1\|3317922_3319077_+\|integrase	site-specific integrase	A0A221SAN4	Ralstonia_phage	6.0e-47	36.2
WP_068765907.1\|3319198_3320065_+	WYL domain-containing protein	NA	NA	NA	NA
WP_071165181.1\|3320371_3321136_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_156894284.1\|3321132_3322629_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_083392718.1\|3324372_3325089_+	hypothetical protein	NA	NA	NA	NA
WP_071166991.1\|3325124_3326252_-	Fic family protein	D7RWK9	Brochothrix_phage	8.5e-06	24.2
WP_083392719.1\|3326372_3326612_-	hypothetical protein	NA	NA	NA	NA
WP_083392782.1\|3326772_3327405_-	hypothetical protein	NA	NA	NA	NA
WP_008336065.1\|3327415_3328135_-	AAA family ATPase	NA	NA	NA	NA
WP_071166992.1\|3328687_3329275_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_071166993.1\|3329261_3331610_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_071166994.1\|3331602_3333585_+	TraM recognition domain-containing protein	NA	NA	NA	NA
WP_156894403.1\|3333912_3335275_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_156894404.1\|3336066_3336267_+	hypothetical protein	NA	NA	NA	NA
WP_156894405.1\|3336978_3337563_+	hypothetical protein	NA	NA	NA	NA
WP_156894406.1\|3337660_3338974_-	hypothetical protein	NA	NA	NA	NA
WP_071167000.1\|3338980_3340615_-\|protease	CAAX prenyl protease-related protein	NA	NA	NA	NA
3339277:3339292	attR	NA	NA	NA	NA
WP_071167001.1\|3340611_3341025_-	hypothetical protein	NA	NA	NA	NA
WP_071167002.1\|3341021_3341873_-	hypothetical protein	NA	NA	NA	NA
WP_071167003.1\|3341919_3344094_-	polysaccharide biosynthesis tyrosine autokinase	NA	NA	NA	NA
WP_071167004.1\|3344087_3344552_-	hypothetical protein	NA	NA	NA	NA
WP_071167005.1\|3344556_3345627_-	hypothetical protein	NA	NA	NA	NA
WP_156894407.1\|3345814_3346447_-	hypothetical protein	NA	NA	NA	NA
WP_083392720.1\|3346747_3347644_+	sulfotransferase	NA	NA	NA	NA
WP_156894408.1\|3347630_3348983_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_083392721.1\|3348688_3350233_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_071167010.1\|3350229_3351528_+	hypothetical protein	NA	NA	NA	NA
WP_071167011.1\|3351524_3352103_+	acyltransferase	NA	NA	NA	NA
WP_083392722.1\|3351946_3353329_+	glycosyltransferase	NA	NA	NA	NA
WP_071167013.1\|3353325_3354555_+	glycosyltransferase	NA	NA	NA	NA
WP_071167014.1\|3354545_3355472_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_071167300.1\|3355555_3356125_+	putative colanic acid biosynthesis acetyltransferase	NA	NA	NA	NA
WP_071167015.1\|3356141_3358163_+	acyltransferase	W6MVL2	Pseudomonas_phage	1.6e-79	41.4
WP_071167301.1\|3358174_3358921_+	glycosyltransferase	NA	NA	NA	NA
WP_083392723.1\|3358968_3360153_-	hypothetical protein	NA	NA	NA	NA
WP_071167017.1\|3360497_3361619_+	GDP-mannose 4,6-dehydratase	M1HXY1	Acanthocystis_turfacea_Chlorella_virus	1.8e-133	64.7
WP_071167018.1\|3361631_3362627_+	GDP-L-fucose synthase	R9S8B8	Prochlorococcus_phage	8.4e-82	48.9
WP_083392724.1\|3362782_3363538_+	response regulator transcription factor	NA	NA	NA	NA
WP_083392725.1\|3363562_3366097_-	response regulator	Q8QKV7	Ectocarpus_siliculosus_virus	5.9e-39	30.8
WP_156894450.1\|3366111_3366621_-	oxidoreductase	NA	NA	NA	NA
WP_156894409.1\|3368295_3369382_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_071165181.1\|3370170_3370935_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_156894284.1\|3370931_3372428_-\|transposase	IS21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

3376084 : 3415268

Acidithiobacillus_phage(26.92%)

tail,portal,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_068765708.1\|3376084_3378007_-	DUF2793 domain-containing protein	A0A0K1LM04	Rhodobacter_phage	1.0e-27	27.3
WP_071167024.1\|3378028_3382027_-	hypothetical protein	A0A0B5A7K5	Paracoccus_phage	1.4e-260	41.4
WP_068765706.1\|3382036_3382468_-	peptidase	A0A1V0DYB6	Dinoroseobacter_phage	3.0e-28	47.4
WP_068765705.1\|3382479_3383364_-	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	1.0e-62	45.4
WP_068765704.1\|3383360_3383570_-	hypothetical protein	NA	NA	NA	NA
WP_068765703.1\|3383566_3384211_-	lysozyme	F8TV87	EBPR_siphovirus	6.1e-41	53.5
WP_068765702.1\|3384339_3384690_-	hypothetical protein	NA	NA	NA	NA
WP_068765701.1\|3384686_3385313_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	6.9e-58	54.4
WP_071167025.1\|3385374_3387837_-\|tail	phage tail tape-measure protein	A0A0U4JEA4	Pseudomonas_phage	4.2e-50	53.0
WP_071167026.1\|3388091_3388529_-	hypothetical protein	NA	NA	NA	NA
WP_071167027.1\|3388540_3389479_-	hypothetical protein	G8DH51	Emiliania_huxleyi_virus	7.4e-96	57.6
WP_068765697.1\|3389503_3389923_-	acyl-CoA transferase	G8DH50	Emiliania_huxleyi_virus	9.7e-40	59.3
WP_083392727.1\|3390027_3391176_+	hypothetical protein	NA	NA	NA	NA
WP_068765904.1\|3391181_3391808_-	hypothetical protein	G8DH49	Emiliania_huxleyi_virus	1.3e-51	53.4
WP_068765696.1\|3391813_3392125_-	hypothetical protein	NA	NA	NA	NA
WP_068765695.1\|3392124_3392460_-	DUF2190 family protein	A0A088C4T4	Shewanella_sp._phage	1.9e-06	42.2
WP_068765694.1\|3392531_3392771_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_068765693.1\|3392777_3393065_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_071167304.1\|3393067_3395086_-	peptidase U37	A0A2I7S8L6	Vibrio_phage	2.8e-76	31.9
WP_071167028.1\|3395105_3396617_-\|portal	phage portal protein	Q75QM9	Wolbachia_phage	2.6e-82	39.1
WP_068765903.1\|3396616_3396826_-	hypothetical protein	NA	NA	NA	NA
WP_071167029.1\|3396828_3398832_-\|terminase	phage terminase large subunit family protein	A0A2H4JIC6	uncultured_Caudovirales_phage	5.6e-218	60.5
WP_071167305.1\|3398779_3399376_-	hypothetical protein	A0A2H4JCL4	uncultured_Caudovirales_phage	7.4e-25	41.5
WP_068767742.1\|3399487_3399712_+	hypothetical protein	NA	NA	NA	NA
WP_068767743.1\|3399807_3400326_+	DUF3489 domain-containing protein	K4HZZ2	Acidithiobacillus_phage	3.0e-14	38.8
WP_083392728.1\|3400377_3400752_-	HNH endonuclease	NA	NA	NA	NA
WP_071167030.1\|3400982_3401192_-	hypothetical protein	K4I1E3	Acidithiobacillus_phage	2.6e-17	68.1
WP_156894411.1\|3401635_3402037_+	hypothetical protein	NA	NA	NA	NA
WP_071167033.1\|3402044_3402239_-	hypothetical protein	NA	NA	NA	NA
WP_071167034.1\|3402419_3403808_-	site-specific DNA-methyltransferase	A0A2H4JGF1	uncultured_Caudovirales_phage	4.8e-75	38.4
WP_071167035.1\|3404220_3404649_-	hypothetical protein	NA	NA	NA	NA
WP_071167306.1\|3404645_3404843_-	hypothetical protein	NA	NA	NA	NA
WP_071167036.1\|3404848_3405385_-	hypothetical protein	K4ICN3	Acidithiobacillus_phage	5.4e-51	64.0
WP_083392783.1\|3405852_3408150_-	AAA family ATPase	A0A1B2LRS1	Wolbachia_phage	1.4e-71	49.4
WP_071167038.1\|3408146_3408914_-	hypothetical protein	K4HZA0	Acidithiobacillus_phage	1.1e-76	57.5
WP_068767736.1\|3408913_3409114_-	hypothetical protein	NA	NA	NA	NA
WP_071167039.1\|3409326_3411018_-	DEAD/DEAH box helicase	A0A0E3JQF5	Streptomyces_phage	1.0e-39	34.2
WP_071167040.1\|3411029_3411629_-	hypothetical protein	K4ICM8	Acidithiobacillus_phage	9.9e-54	63.1
WP_071167041.1\|3411648_3412518_-	ATP-binding protein	K4HZX9	Acidithiobacillus_phage	8.6e-99	61.3
WP_071167042.1\|3412514_3413003_-	hypothetical protein	K4HZ96	Acidithiobacillus_phage	7.1e-26	44.5
WP_068767668.1\|3413030_3413393_-	hypothetical protein	NA	NA	NA	NA
WP_071166986.1\|3413392_3413596_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_068767666.1\|3413798_3414287_-	hypothetical protein	NA	NA	NA	NA
WP_068767665.1\|3414590_3415268_+	helix-turn-helix domain-containing protein	A0A0M3LPF9	Mannheimia_phage	5.1e-22	31.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP017782

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17703 : 60370

Acidithiobacillus_phage(18.18%)

integrase,transposase

attL 26380:26439|attR 57048:59553

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_078527637.1\|17703_19059_+\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	5.0e-45	29.7
WP_156894452.1\|19072_19429_-	hypothetical protein	NA	NA	NA	NA
WP_083392789.1\|19432_20539_-	hypothetical protein	NA	NA	NA	NA
WP_083392790.1\|20535_21330_-	hypothetical protein	NA	NA	NA	NA
WP_071167322.1\|21396_21594_-	hypothetical protein	NA	NA	NA	NA
WP_071167323.1\|22991_23555_-	hypothetical protein	K4HZD4	Acidithiobacillus_phage	1.8e-25	42.2
WP_156894453.1\|23547_25134_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	8.2e-47	29.9
WP_083392815.1\|25298_25595_-	hypothetical protein	A0A125RN89	Pseudomonas_phage	5.5e-05	40.3
WP_083392792.1\|25757_26474_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
26380:26439	attL	NA	NA	NA	NA
WP_071165181.1\|26516_27281_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_156894284.1\|27277_28774_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	9.2e-16	29.3
WP_156894454.1\|30357_30855_-	hypothetical protein	NA	NA	NA	NA
WP_156894455.1\|31247_31520_-	hypothetical protein	NA	NA	NA	NA
WP_071167328.1\|31516_31726_-	hypothetical protein	NA	NA	NA	NA
WP_071167329.1\|32930_33983_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_071167330.1\|34912_35212_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_071167331.1\|35208_35553_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_071167456.1\|36931_38101_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_071167333.1\|38258_39284_-	type IV secretion system protein	NA	NA	NA	NA
WP_071167334.1\|39283_39703_-	hypothetical protein	NA	NA	NA	NA
WP_071167335.1\|39720_40755_-	type II secretion system protein E	NA	NA	NA	NA
WP_071167336.1\|40756_42082_-	conjugal transfer protein	NA	NA	NA	NA
WP_156894456.1\|42078_42780_-	conjugal transfer protein TrbG	NA	NA	NA	NA
WP_071167457.1\|42776_43424_-	type IV secretion system protein	NA	NA	NA	NA
WP_071167337.1\|43438_44236_-	conjugal transfer protein TraF	NA	NA	NA	NA
WP_071167338.1\|44232_45399_-	transglycosylase SLT domain-containing protein	A0A1P8CWQ1	Bacillus_phage	1.2e-26	51.1
WP_071167339.1\|45403_45619_-	hypothetical protein	NA	NA	NA	NA
WP_071167340.1\|45615_48000_-	type IV secretion system protein B4	NA	NA	NA	NA
WP_071167341.1\|47989_48268_-	type IV secretion system protein VirB3	NA	NA	NA	NA
WP_018001732.1\|48289_48580_-	TrbC/VirB2 family protein	NA	NA	NA	NA
WP_071167342.1\|48600_49284_-	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	4.8e-20	55.8
WP_010138156.1\|49240_49567_-	hypothetical protein	NA	NA	NA	NA
WP_071167458.1\|49812_50040_+	hypothetical protein	NA	NA	NA	NA
WP_071167343.1\|50054_50375_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_028095408.1\|50380_50623_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_071167344.1\|51309_51738_+	hypothetical protein	NA	NA	NA	NA
WP_156894457.1\|51974_52166_+	hypothetical protein	NA	NA	NA	NA
WP_156894458.1\|52195_53321_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.0e-35	35.6
WP_083392793.1\|55068_55470_+	hypothetical protein	NA	NA	NA	NA
WP_071167347.1\|55466_56111_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_071167348.1\|56129_57047_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_071165181.1\|57184_57949_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_156894284.1\|57945_59442_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	9.2e-16	29.3
WP_083392793.1\|59588_59990_-	hypothetical protein	NA	NA	NA	NA
57048:59553	attR	NA	NA	NA	NA
WP_156894459.1\|60043_60370_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

85716 : 134407

Escherichia_phage(27.27%)

integrase,transposase

attL 85607:85666|attR 138098:140632

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
85607:85666	attL	NA	NA	NA	NA
WP_156894284.1\|85716_87213_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	9.2e-16	29.3
WP_071165181.1\|87209_87974_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_071167461.1\|88122_89286_-\|integrase	tyrosine-type recombinase/integrase	A0A097EYL9	Mycobacterium_phage	2.6e-10	30.0
WP_071167365.1\|91049_91694_+	antitoxin of toxin-antitoxin stability system	A0A2I6PI07	Pseudomonas_phage	1.6e-20	32.6
WP_071167366.1\|92727_93024_-	hypothetical protein	NA	NA	NA	NA
WP_071167367.1\|93201_97590_+	methylase	A0A076FMQ0	Aureococcus_anophage	3.2e-16	23.9
WP_083392797.1\|97593_97899_+	hypothetical protein	NA	NA	NA	NA
WP_083392798.1\|97895_98933_+	DNA primase	A0A2I7R8M6	Vibrio_phage	4.9e-08	33.7
WP_071167368.1\|100251_101208_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_071167463.1\|101194_102190_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_083392816.1\|103735_104230_+	hypothetical protein	NA	NA	NA	NA
WP_071167369.1\|104592_105525_+	DUF2493 domain-containing protein	NA	NA	NA	NA
WP_071167370.1\|105609_105876_+	WGR domain-containing protein	NA	NA	NA	NA
WP_156894474.1\|107616_107712_+	hypothetical protein	NA	NA	NA	NA
WP_071167372.1\|107794_109507_+	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_071167373.1\|109605_111090_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_071167374.1\|111116_112265_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_071167375.1\|112347_113124_+	hypothetical protein	NA	NA	NA	NA
WP_071167313.1\|113154_113382_-	hypothetical protein	NA	NA	NA	NA
WP_071167314.1\|113563_114907_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_071167315.1\|114903_116814_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_083392785.1\|116810_117800_-	hypothetical protein	NA	NA	NA	NA
WP_071167316.1\|117793_118567_-	molecular chaperone TorD family protein	NA	NA	NA	NA
WP_083392786.1\|118559_119228_-	4Fe-4S dicluster domain-containing protein	A0A077SL61	Escherichia_phage	7.2e-45	38.6
WP_071167317.1\|119243_121808_-	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	4.3e-98	32.9
WP_083392787.1\|121822_123295_-	c-type cytochrome	NA	NA	NA	NA
WP_071167319.1\|124187_124484_-	hypothetical protein	NA	NA	NA	NA
WP_071167320.1\|125028_125295_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_078527637.1\|126977_128333_+\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	5.0e-45	29.7
WP_156894452.1\|128346_128703_-	hypothetical protein	NA	NA	NA	NA
WP_083392789.1\|128706_129813_-	hypothetical protein	NA	NA	NA	NA
WP_083392790.1\|129809_130604_-	hypothetical protein	NA	NA	NA	NA
WP_071167322.1\|130670_130868_-	hypothetical protein	NA	NA	NA	NA
WP_071167323.1\|132265_132829_-	hypothetical protein	K4HZD4	Acidithiobacillus_phage	1.8e-25	42.2
WP_156894460.1\|132832_134407_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	8.1e-47	29.9
138098:140632	attR	NA	NA	NA	NA

DBSCAN-SWA_3

149521 : 158001

Ochrobactrum_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071167392.1\|149521_151678_-	DNA-binding protein	G8DH78	Emiliania_huxleyi_virus	1.9e-30	33.9
WP_071167393.1\|151793_152885_-	hypothetical protein	L7TKN6	Rhizobium_phage	2.7e-17	27.5
WP_071167394.1\|153107_154082_-	plasmid partitioning protein RepB	A0A240F4U0	Ochrobactrum_phage	4.3e-30	33.3
WP_071167395.1\|154081_155284_-	plasmid partitioning protein RepA	A0A240F4U1	Ochrobactrum_phage	4.4e-93	49.6
WP_071167396.1\|155690_156317_+	SOS response-associated peptidase	V9IQW7	Stenotrophomonas_phage	4.9e-19	34.7
WP_071167397.1\|156636_158001_-	chromate efflux transporter	A0A219VHC2	Ochrobactrum_phage	2.4e-31	74.1

DBSCAN-SWA_4

187197 : 238290

Escherichia_phage(22.22%)

integrase,transposase

attL 186271:186330|attR 235867:238400

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
186271:186330	attL	NA	NA	NA	NA
WP_156894284.1\|187197_188694_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	9.2e-16	29.3
WP_001297013.1\|189029_190220_+	tetracycline efflux MFS transporter Tet(C)	NA	NA	NA	NA
WP_002310911.1\|190123_190462_+	hypothetical protein	NA	NA	NA	NA
WP_071533317.1\|190458_190644_-	hypothetical protein	NA	NA	NA	NA
WP_000015696.1\|190669_190948_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001067855.1\|191305_192010_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_071167423.1\|192021_192873_-	AAA family ATPase	NA	NA	NA	NA
WP_083392807.1\|193174_195952_-	DEAD/DEAH box helicase	A0A0R6PHP9	Moraxella_phage	2.9e-23	39.1
WP_071167424.1\|195961_197272_-	ATP-binding protein	NA	NA	NA	NA
WP_156894464.1\|197258_199880_-	hypothetical protein	NA	NA	NA	NA
WP_071167426.1\|200118_201426_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_071167427.1\|201422_201719_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_083392808.1\|201893_202139_-	hypothetical protein	NA	NA	NA	NA
WP_083392809.1\|202259_204077_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_156894465.1\|204054_204600_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_083392810.1\|205129_205855_+	AAA family ATPase	NA	NA	NA	NA
WP_071167431.1\|205854_206496_+	hypothetical protein	NA	NA	NA	NA
WP_156894466.1\|206516_206768_+	hypothetical protein	NA	NA	NA	NA
WP_071167433.1\|207122_207527_-	single-stranded DNA-binding protein	Q6V7S6	Burkholderia_virus	8.5e-17	41.6
WP_071167434.1\|208112_209132_-	hypothetical protein	NA	NA	NA	NA
WP_071165181.1\|209452_210217_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_156894284.1\|210213_211710_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	9.2e-16	29.3
WP_156894467.1\|212504_212936_-	hypothetical protein	NA	NA	NA	NA
WP_071167435.1\|213237_213954_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_071167436.1\|213950_217166_-	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	5.1e-64	27.1
WP_071167437.1\|217162_218011_-	haloacid dehalogenase-like hydrolase	NA	NA	NA	NA
WP_156894468.1\|218012_219356_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_071167439.1\|219219_220248_-	virulence RhuM family protein	Q9JMN3	Wolbachia_phage	2.1e-72	46.8
WP_071167440.1\|220240_221758_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.2e-79	38.0
WP_071167470.1\|221754_222348_-	hypothetical protein	NA	NA	NA	NA
WP_071167441.1\|222692_222962_-	WGR domain-containing protein	NA	NA	NA	NA
WP_071167442.1\|223047_223980_-	DUF2493 domain-containing protein	NA	NA	NA	NA
WP_156894476.1\|224345_225233_-	DNA primase	A0A0H5AWB1	Pseudomonas_phage	2.2e-17	37.2
WP_071167443.1\|225320_226376_+	hypothetical protein	A0A2I7R8M6	Vibrio_phage	1.1e-07	33.7
WP_009574301.1\|226454_227699_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1P7C7	Bacillus_phage	2.0e-11	26.1
WP_071167444.1\|227695_228652_+\|integrase	tyrosine-type recombinase/integrase	A0A076G872	Mycobacterium_phage	2.7e-05	32.3
WP_009574303.1\|228638_229634_+\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJJ6	Virus_Rctr41k	1.2e-08	26.2
WP_071167445.1\|229650_230703_-	hypothetical protein	A0A2I7R8M6	Vibrio_phage	1.1e-07	33.7
WP_071167446.1\|231019_235378_-	methylase	A0A076FMQ0	Aureococcus_anophage	1.4e-16	24.7
WP_071167447.1\|235553_235850_+	hypothetical protein	NA	NA	NA	NA
WP_071165181.1\|236032_236797_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-44	40.8
WP_156894284.1\|236793_238290_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	9.2e-16	29.3
235867:238400	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP017783

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP017781

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP017782

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection