CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP016635	Francisella tularensis subsp. novicida PA10-7858 chromosome, complete genome	2 crisprs	cas3,csa3,PD-DExK,cas9,RT,DEDDh,cas2,cas1,cas4,cas12a	0	16	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016635_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016635_1

800288-801118

orTypeII

Consensus_repeat	Method
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	PILER-CR
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	CRISPRCasFinder
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	CRT

11 spacers

cas9

The CRISPR arrays of NZ_CP016635_1

>merge|NZ_CP016635|1|800288-801118|PILER-CR,CRISPRCasFinder,CRT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACTTAAGATGTTTTCAACACCCCTAAGAGTAAAATACTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACTTATTGAATCCTTACTGTTGTGGAGGTGGGTAGTGCCTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACTTGTATAAATCTATTTTAGACATTTTCTATCCGTTCTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACTATTGTTTTTGTGTCAATTCAGCATTCTCTAAATCCTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACTGCTATTTTTTCCATTTTCCCTATCCACTAACTCAACTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACACGGTGGGCTAATATATGGCTATTATTGCATATACCTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACTTATTGATGTTACCGCAAGGACTTAGTATCATAACTCTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACATTGGCTTAATAATTACGAATAACGCAATAAAAACTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACATAGGTTTATCTAAAAATCGTGTAAATTTTAGATTCTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACTTATTGATGTTACCGCAAGGACTTAGTATCATAACTCTAACAGTAGTTTACCAAATAATTCAGCAACTGAAACAAGCATATTACTGATTTATTTTGTGAATTAGTTGACTAACAGTAGTTTACTAAATAATTCAGCAACTGAAAC

>NZ_CP016635|1|1|800288-801118|PILER-CR
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTAAGATGTTTTCAACACCCCTAAGAGTAAAATA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGAATCCTTACTGTTGTGGAGGTGGGTAGTGC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTGTATAAATCTATTTTAGACATTTTCTATCCGTT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TATTGTTTTTGTGTCAATTCAGCATTCTCTAAATC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TGCTATTTTTTCCATTTTCCCTATCCACTAACTCAA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ACGGTGGGCTAATATATGGCTATTATTGCATATAC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGATGTTACCGCAAGGACTTAGTATCATAACT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ATTGGCTTAATAATTACGAATAACGCAATAAAAA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ATAGGTTTATCTAAAAATCGTGTAAATTTTAGATT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGATGTTACCGCAAGGACTTAGTATCATAACT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	AAGCATATTACTGATTTATTTTGTGAATTAGTTGA
CTAACAGTAGTTTACTAAATAATTCAGCAACTGAAAC

>NZ_CP016635|1|1|800288-801118|CRISPRCasFinder
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTAAGATGTTTTCAACACCCCTAAGAGTAAAATA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGAATCCTTACTGTTGTGGAGGTGGGTAGTGC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTGTATAAATCTATTTTAGACATTTTCTATCCGTT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TATTGTTTTTGTGTCAATTCAGCATTCTCTAAATC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TGCTATTTTTTCCATTTTCCCTATCCACTAACTCAA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ACGGTGGGCTAATATATGGCTATTATTGCATATAC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGATGTTACCGCAAGGACTTAGTATCATAACT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ATTGGCTTAATAATTACGAATAACGCAATAAAAA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ATAGGTTTATCTAAAAATCGTGTAAATTTTAGATT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGATGTTACCGCAAGGACTTAGTATCATAACT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	AAGCATATTACTGATTTATTTTGTGAATTAGTTGA
CTAACAGTAGTTTACTAAATAATTCAGCAACTGAAAC

>NZ_CP016635|1|1|800288-801118|CRT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTAAGATGTTTTCAACACCCCTAAGAGTAAAATA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGAATCCTTACTGTTGTGGAGGTGGGTAGTGC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTGTATAAATCTATTTTAGACATTTTCTATCCGTT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TATTGTTTTTGTGTCAATTCAGCATTCTCTAAATC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TGCTATTTTTTCCATTTTCCCTATCCACTAACTCAA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ACGGTGGGCTAATATATGGCTATTATTGCATATAC
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGATGTTACCGCAAGGACTTAGTATCATAACT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ATTGGCTTAATAATTACGAATAACGCAATAAAAA
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	ATAGGTTTATCTAAAAATCGTGTAAATTTTAGATT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	TTATTGATGTTACCGCAAGGACTTAGTATCATAACT
CTAACAGTAGTTTACCAAATAATTCAGCAACTGAAAC	AAGCATATTACTGATTTATTTTGTGAATTAGTTGA
CTAACAGTAGTTTACTAAATAATTCAGCAACTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016635.1\|WP_071304236.1\|804127_805078_-\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_CP016635.1\|WP_003023300.1\|791149_791701_+\|putative-Fe-S-cluster-assembly-protein-SufT	unknown	unknown	gnl\|CDD\|213809
NZ_CP016635.1\|WP_071304234.1\|801824_802910_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|275338
NZ_CP016635.1\|WP_071304238.1\|806051_806804_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|349968
NZ_CP016635.1\|WP_071304239.1\|806945_808898_+\|BCCT-family-transporter	unknown	unknown	gnl\|CDD\|376718
NZ_CP016635.1\|WP_003016538.1\|790779_791136_+\|iron-sulfur-cluster-assembly-accessory-protein	unknown	unknown	gnl\|CDD\|223393
NZ_CP016635.1\|WP_071304230.1\|789535_790759_+\|SufS-family-cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP016635.1\|WP_003033590.1\|786467_787310_+\|prephenate-dehydratase	unknown	unknown	gnl\|CDD\|223155
NZ_CP016635.1\|WP_003036243.1\|803147_803597_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP016635.1\|WP_003036232.1\|791712_792201_+\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NZ_CP016635.1\|WP_071304235.1\|803609_803963_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016635.1\|WP_071304231.1\|794411_799301_+\|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12	cas9	cd09704_cas9_CAS-II-B	gnl\|CDD\|274401
NZ_CP016635.1\|WP_014549651.1\|808890_809367_-\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP016635.1\|WP_003033610.1\|802902_803151_+\|glutaredoxin	unknown	unknown	gnl\|CDD\|239510
NZ_CP016635.1\|WP_003016533.1\|792205_792451_+\|YfhL-family-4Fe-4S-dicluster-ferredoxin	unknown	unknown	gnl\|CDD\|235941
NZ_CP016635.1\|WP_003033601.1\|792557_793739_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP016635.1\|WP_003033621.1\|809495_810350_+\|bifunctional-methionine-sulfoxide-reductase-B/A-protein	unknown	unknown	gnl\|CDD\|235499
NZ_CP016635.1\|WP_014549641.1\|787335_788004_+\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|307807
NZ_CP016635.1\|WP_071304237.1\|805172_805916_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP016635.1\|WP_014549642.1\|788059_789433_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233

Protein	Function_ID	Function_description	E-value
NZ_CP016635.1\|WP_071304236.1\|804127_805078_-\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	5.27273e-67
NZ_CP016635.1\|WP_003023300.1\|791149_791701_+\|putative-Fe-S-cluster-assembly-protein-SufT	gnl\|CDD\|213809	TIGR03406, FeS_long_SufT, probable FeS assembly SUF system protein SufT. The function is unknown for this protein family, but members are found almost always in operons for the the SUF system of iron-sulfur cluster biosynthesis. The SUF system is present elsewhere on the chromosome for those few species where SUF genes are not adjacent. This family shares this property of association with the SUF system with a related family, TIGR02945. TIGR02945 consists largely of a DUF59 domain (see pfam01883), while this protein is about double the length, with a unique N-terminal domain and DUF59 C-terminal domain. A location immediately downstream of the cysteine desulfurase gene sufS in many contexts suggests the gene symbol sufT. Note that some other homologs of this family and of TIGR02945, but no actual members of this family, are found in operons associated with phenylacetic acid (or other ring-hydroxylating) degradation pathways. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	8.7206e-99
NZ_CP016635.1\|WP_071304234.1\|801824_802910_+\|radical-SAM-protein	gnl\|CDD\|275338	TIGR04545, rSAM_ahbD_hemeb, heme b synthase. Members of this family are AhbD (alternative heme biosynthetic protein D), a radical SAM enzyme in sulfate-reducing bacteria and methanogens that performs the last decarboxylations to synthesize heme b from Fe-coproporphyrin III. Members include DVU_0855, previously included in error in TIGR04055, the NirJ2 family thought to be involved in heme d1 biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	1.43033e-140
NZ_CP016635.1\|WP_071304238.1\|806051_806804_-\|RNA-methyltransferase	gnl\|CDD\|349968	cd18095, SpoU-like_rRNA-MTase, SAM-dependent rRNA methylase related to SpoU-TrmH. RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	4.64484e-53
NZ_CP016635.1\|WP_071304239.1\|806945_808898_+\|BCCT-family-transporter	gnl\|CDD\|376718	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter.	0
NZ_CP016635.1\|WP_003016538.1\|790779_791136_+\|iron-sulfur-cluster-assembly-accessory-protein	gnl\|CDD\|223393	COG0316, sufA, Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones].	1.01145e-25
NZ_CP016635.1\|WP_071304230.1\|789535_790759_+\|SufS-family-cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP016635.1\|WP_003033590.1\|786467_787310_+\|prephenate-dehydratase	gnl\|CDD\|223155	COG0077, PheA, Prephenate dehydratase [Amino acid transport and metabolism].	6.08673e-99
NZ_CP016635.1\|WP_003036243.1\|803147_803597_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	2.54542e-26
NZ_CP016635.1\|WP_003036232.1\|791712_792201_+\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	4.2984e-85
NZ_CP016635.1\|WP_071304231.1\|794411_799301_+\|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12	gnl\|CDD\|274401	TIGR03031, cas_csx12, CRISPR system subtype II-B RNA-guided endonuclease Cas9/Csx12. Members of this family of CRISPR-associated (cas) protein are found, so far, in CRISPR/cas loci in Wolinella succinogenes DSM 1740, Legionella pneumophila str. Paris, and Francisella tularensis, where the last probably is an example of a degenerate CRISPR locus, having neither repeats nor a functional Cas1. The characteristic repeat length is 37 base pairs and period is about 72. One region of this large protein shows sequence similarity to pfam01844, HNH endonuclease.	0
NZ_CP016635.1\|WP_014549651.1\|808890_809367_-\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	5.73436e-41
NZ_CP016635.1\|WP_003033610.1\|802902_803151_+\|glutaredoxin	gnl\|CDD\|239510	cd03418, GRX_GRXb_1_3_like, Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide reductase. It contains a redox active CXXC motif in a TRX fold and uses a similar dithiol mechanism employed by TRXs for intramolecular disulfide bond reduction of protein substrates. Unlike TRX, GRX has preference for mixed GSH disulfide substrates, in which it uses a monothiol mechanism where only the N-terminal cysteine is required. The flow of reducing equivalents in the GRX system goes from NADPH -> GSH reductase -> GSH -> GRX -> protein substrates. By altering the redox state of target proteins, GRX is involved in many cellular functions including DNA synthesis, signal transduction and the defense against oxidative stress. Different classes are known including E. coli GRX1 and GRX3, which are members of this subfamily.	1.16836e-12
NZ_CP016635.1\|WP_003016533.1\|792205_792451_+\|YfhL-family-4Fe-4S-dicluster-ferredoxin	gnl\|CDD\|235941	PRK07118, PRK07118, Fe-S cluster domain-containing protein.	1.36021e-07
NZ_CP016635.1\|WP_003033601.1\|792557_793739_+\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	3.60897e-21
NZ_CP016635.1\|WP_003033621.1\|809495_810350_+\|bifunctional-methionine-sulfoxide-reductase-B/A-protein	gnl\|CDD\|235499	PRK05550, PRK05550, bifunctional methionine sulfoxide reductase B/A protein; Provisional.	1.08131e-180
NZ_CP016635.1\|WP_014549641.1\|787335_788004_+\|M48-family-metallopeptidase	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	1.05321e-50
NZ_CP016635.1\|WP_071304237.1\|805172_805916_+\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.29884e-21
NZ_CP016635.1\|WP_014549642.1\|788059_789433_+\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0

>NZ_CP016635.1|WP_071304231.1|794411_799301_+|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12
MNFKILPIAIDLGVKNTGVFSAFYQKGTSLERLDNKNGKVYELSKDSYTLLMNNRTARRHQRRGIDRKQLVKRLFKLIWTEQLNLEWDKDTQQAISFLFNRRGFSFITDGYSPEYLNIVPEQVKAILMDIFDDYNGEDDLDSYLKLATEQESKISEIYNKLMQKILEFKLRKLCTDIKDDKVSTKTLKEITSYEFELLADYLANYSEILKTQKFSYTDKQGNLKELSYYHHDKYNIQEFLKRHATINIQILDTLLTDDLDIWNFNFEKFDFDKNEEKLQNQEDKDHIQAHLHHFVFAVNKIKSEMASGGRHRSQYFQEITNVLDENNHQQGYLKNFCENLHNKKYSNLSVKNLVNLIGNLSNLELKPLRKYFNDKIHAKADHWDEQKFTETYCHWILGEWRVGVKDQDKKDGAKYSYKDLCNELKQKVTKAGLVDFLLELDPCRTIPPYLDNNNRKPPKCQSLILNPKFLDNQYPNWQQYLQELKKLQSIQNYLESFETDLKVLKSSKDQPYFVEYKSSNQQIASGQRDYKDLDARILQFIFDRVKASDELLLNEIYFQAKKLKQKASSELEKLESSKKLDEVIANSQLSQILKSQHTNGIFEQGTFLHLVCKYYKQRQRARDSRLYIMPEYRYDKKLHKYNNTGRFDDDNQLLTYCNHKPRQKRYQLLNDLAGVLQVSPNFLKDKIGSDDDLFISKWLVEHIRGFKKACEDSLKIQKDNRGLLNHKINIARNTKGKCEKEIFNLICKIEGSEDKKGNYKHGLAYELGVLLFGEPNEASKPEFDRKIKKFNSIYSFAQIQQIAFAERKGNANTCAVCSADNAHRMQQIKITEPVEDNKDKIILSAKAQRLPAIPTRIVDGAVKKMATILAKNIVDDNWQNIKQVLSAKHQLHIPIITESNAFEFEPALADVKGKSLKDRRKKALERISPENIFKDKNNRIKEFAKGISAYSGANLTDGDFDGAKEELDHIIPRSHKKYGTLNDEANLICVTSGDNKNKGNRIFCLRDLANNYKLKQFETTDDLEIEKKIADTIWDANKKDFKFGNYRSFINLTPQEQKAFRHALFLADENPIKQAVIRAINNRNRTFVNGTQRYFAEVLANNIYLRAKKENLNTDKISFDYFGIPTIGNGRGIAEIRQLYEKVDSDIQAYAKGDKPQASYSHLIDAMLAFCIAADEHRNDGSIGLEIDKNYSLYPLDKKTGEVFTKDIFSQIKITDNEFSDKKLVRKKATEGFNTHRQMTRDGIYAENYLPILIHKELDEVRKGYTWKNSEEIKIFKGKKYDIQQLNNLLYCLKFVDKPISIDIQISTLEELRNILTTNNIAATAEYYYINLKTQKLHEYYIENYNTALGYKKYTKEMEFLRSLAYRSERVKIKSIDDVKQVLDKDSNFIIGKITLPFKKEWQRLYREWQNTTIKDDYEFLKSFFNVKSITKLHKKVRKDFSLPISTNEGKFLVKRKTWDNNFIYQILNDSDSRVDGTKPFIPAFDISKNEIVEAIIDSFTSKNIFWLPKNIELQKVDNKNIFAIDTSKWFEVETPSDLRDIGVATIQYKIDNNSRPKVRVKLDYVIDDDSKINYFTNHSLLKSRYPDKVLEILKQSTIIEFESSGFNKTIKEMLGMTLAGIYNETSNN
>NZ_CP016635.1|WP_003033601.1|792557_793739_+|OmpA-family-protein
MMRLKSIVIATTVLLGSATASIAAGSDNIDTSANTNSATTQSSGFAANNFIAPFANTYSALTNKDNTWGPQDRTGQWYLGVDANGLAGTPNSPSGAGANFTIGYNINKYFAVQYNQLVGRVFAGLGEGVVNFSNNTMFTPYAAGGAGWANLAGQATGAWDVGGGLKFELSRNVQASVDYRYIQTMAPSNISGANGRAGTNMIGAGLTWFFGGKDTTNNDTGNIQDNGATTAAQTVAMPTIDESKYVLPAGIKQCEGNFNLTEDGVACYTVNGDDVTVYLDTKFAYDKATLNAKGKKAIASFVNFIKDSNIGSVTVKGYASQGQTGSEFDIYNQKLSEKRAQAVADYMKQLGLDSEKIITKGFGYDDTLGGIPKSDPRNQRVEASVSAPLKEAN
>NZ_CP016635.1|WP_003016533.1|792205_792451_+|YfhL-family-4Fe-4S-dicluster-ferredoxin
MALLITDECINCDICEPECPNEAISQGEEYYEIDPNKCTECVGHFEESQCTKVCPIRCIIIDPNNIETHQQLLDKYNSLVS
>NZ_CP016635.1|WP_003036232.1|791712_792201_+|pantetheine-phosphate-adenylyltransferase
MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDICIREQMIKEVFKDNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
>NZ_CP016635.1|WP_003023300.1|791149_791701_+|putative-Fe-S-cluster-assembly-protein-SufT
MKPTDVTIIRRQVKAIAVPFGNEIELMPGQEVLVTQDKGGSFTLNVNGNLLHLDGKDADAIGKQIVRYPVEGYDIKPGDPINMDAIWDQMRTVYDPEIPVNIVDLGLIYNIITRKLENGNFHVIIDMTLTAPGCGMGPVLMTDVEKRVAMLPNVDKVDVVMVFDPPWNSEMMTEAAKLELGLF
>NZ_CP016635.1|WP_003016538.1|790779_791136_+|iron-sulfur-cluster-assembly-accessory-protein
MVEVFDPNASSILEVTDAAAKHFKKHLDKHDGCIGIYVGTKVMGCSGLAYDVDFVKQQPQDTQKVQQHGINFFVSNKSMDFLNGLKIDYVKHDFGLYKLEYTNPNESARCGCGESFTV
>NZ_CP016635.1|WP_071304230.1|789535_790759_+|SufS-family-cysteine-desulfurase
MYDVNEIRQDFPFLAQKINNKSVLFFDTGASAQKPQVVIECVAEAYAYNYANVHRGVYSLSQEASEKYENVRQIVQKFLNSKSADEIVITKGTTEAINLVASSIGKGIIRSDDEIVVTEMEHHANFVPWQMLCEDKNLDFKVAAVKDNGELDIDNLLALVTAKTKILAITLCSNVLGTINPVKEIIKQVREINPNIIVLVDGAQAVIHTKVDVQDLDCDFFVFSGHKLYGPTGVGILYGKYELLKQLPPYNYGGDMVDEVTIAKTTFALPPYRFEAGTPNIVEAIGLGRAIEYVDSIGMINIEKHEQKLLEYATTELNKIDGLTIFGQAKHKAGVITFDIQGCNAGDIGELLAIKGICVRTGKHCAHPLMYRMGVTSTVRMSFGMYNTFEEIDLFIIALKKVISQLK
>NZ_CP016635.1|WP_014549642.1|788059_789433_+|L-serine-ammonia-lyase
MESTFELFSIGVGPSSSHTIGPMRAGCDFINLYKDKLPQTKRVKIDLFGSLALTGKGHKTDYAVVLGVMGFLPESVDIELAKKLYDECLRNKKLNLGQEFEIDFDYDKDLVFHYNEFLPEHANGMRFSLFNGEELLCEKEYFSIGGGFIVDKKQIKKDTVPTEVSCDKPYKFSTMAELRELCQRDNKTIDEIMFENEKTAYGEQQSLDKLAEIWHVMETSIEKGLTCAEATLPGGLKVRKRAPSMIRKLKEQNIVNTDFNYLNAFAIAVNEQNACGERVVTAPTNGAAGVIPAVLKYYLQTHEIVNQQELKEVVNKYLLVCAAIGILYKSGASISAAEVGCQGEVGVACSMAAAGYCALLGGDLDSIESAAEIGMEHNLGLTCDPIGGLVQIPCIERNAMGAVQAINAAKLAYLDTGEKRFVGLDYVIKVMYETGLDMSSKYKETSLGGLATNVPVC
>NZ_CP016635.1|WP_014549641.1|787335_788004_+|M48-family-metallopeptidase
MSYKVKIIYRDVANLKISLNKDGLVTVVSPQKVTKKEIFKILESKKAWLDKHAKRLSVNQKYDYQNYTLNDGDSVYFLGREYPIKLVESKHNIVSYHDDHIQILLNPSVITNRQFKLQLLEEFYKDQADIILNNLVAKYLKITNQEITRVTIKKTKTRWGSCNYVKKTINLNFNLVLRDIQAIEYVVLHEIAHLTHPNHSKEFYAYVASYMPDWKVREKRLK
>NZ_CP016635.1|WP_003033590.1|786467_787310_+|prephenate-dehydratase
MIKVSFQGEHGAYSEQAITNFLELQNIKDFQTVPCWSFSDAIEHTISGKSNFVMIPVENSLAGSVVPAYDELIKSNLKVKAEVVLKIKHCLMGLNDVEISEIESVISHPQALSQCANSLKKLKLTPEAFVDTAGAAKYIFEKNKRNHLAIAGELAAKTYGLKIFQHELEDEQFNYTRFLLMGYDDIKVNSADNKYKTTIIFSVEDKSNALVNTLNVFGKYNINLTKIESRPSRNRAWNYLFFIDFEGSDDDLNVQQALLEVLKKSTFLKVLGSYKSYHFS
>NZ_CP016635.1|WP_071304234.1|801824_802910_+|radical-SAM-protein
MKHQLKWMAWETTRRCNLKCVHCRSSSDCEVLGHPDFSTEEGFRIIDSIVAFANPVLVLSGGEPLLRADIFELAEYGTNKGLRMALATNGSLVTDEICEKIKNANISIVSLSIDGATAATHDDFRNQKGAFEATINAAKLFRKHDIPFLINSSFTKRNQHEITDVYKLAKSLEATAWYLFMIVPTGRGEELIQELIDIDDYQDILNWHYDIEADEQDMLVRPTCAPHYYRIRFERNKEDNAKVRSRALSFGTGGGKGCIAGQSICLLDVDGNIYPCSYLPVSAGNIKEKSFADIWQNSNVLEDMRNFSAYEGKCGACEFIKICGGCRARAYNIHGNYLAEEPFCNHVPIRMRNIEEKQSNE
>NZ_CP016635.1|WP_003033610.1|802902_803151_+|glutaredoxin
MNNFKSIVLYRMVTPEKICPYGLKAKALFEQKGWSFEDNHLKTRAETDAFKAKYNLQTTPLIFIDGQQIGGYSDLLEFLGEK
>NZ_CP016635.1|WP_003036243.1|803147_803597_+|acyl-CoA-thioesterase
MNQQLKYFVLSTQVLPEHIDPNKHLNNIVYLQWMQDVAIAHVKANGVFELTESQGLTWFARKHTIEYLSQGFLGDDIAVVTWVESITKISTFRKYHIYRKSDKTLLCKADTLWVMVNAHRGKPAKIPTELVEIFDKYNNFEIDDIKNLI
>NZ_CP016635.1|WP_071304235.1|803609_803963_-|hypothetical-protein
MSKCKTHQNHEHKHQDDCGHTKIKHGDHYDYLHDGHLHHEHNGHYDEHTLEVTKKNPDGCHPIKEDCSSHVHGPNCGHEAVPHGDHIDYIVDGRLHHPHGDHCDDHGSVEVIKNDKK
>NZ_CP016635.1|WP_071304236.1|804127_805078_-|linear-amide-C-N-hydrolase
MTPLIILSFLQFSFGCTWFSFENDKEHYFIGRTMEWPGDLNTKITLVPRGYKFGNFTTHYGFVGMSHNGNFSDGMNEYGLAVSALWLSSSKYPDKKDADYNITMLLPYVLGNTTTVAQAVEFIKKHKFYTSVLPEISDKVEITVHFAISDAQGNSVVVEFINGKTKIYDNKIKVLTNDPAYDEQLKLLKKYQDREIKEDKFIAFDYSSEGRFAKMAAFNITKANTPDDLTAVNHAWSIINTVDIPQGSLYWRWVSSKPQFTSYSVVGDLSNRVYYFRTWDNYDIRKVDLSKIDFAKAKYQADTIFGQADYQEFKFK
>NZ_CP016635.1|WP_071304237.1|805172_805916_+|IS5-family-transposase
MNYHIKEVFWSSILSFLKSQRGIHTNDEAKLRLFIEAVFYVLRTGCQWRMLPFYYGKYRSIHKRFKDWCDKGIFSRLFKSVQNPDLQEVMLDSTIARAHACATGYDKDDNQAIGRSVGGITTKIHAMTDALGNPIEVLLSEGKTHDSKVAIDLLQNIYNTKVIADRAYHSNGIRQHIQSISSEAVIPCKSNTLNHISFDSHVYKERHLIENFFSKIKHFRRVFSRFDKTISVYLGMIKLACTFIWLR
>NZ_CP016635.1|WP_071304238.1|806051_806804_-|RNA-methyltransferase
MKNLSQKLYKEIKKLHSSQGRKKSQYYVIEGLRCSQEALKRLPQQQIIAILVTEKADNPNYPLNKKYIITEKDFEALSQTQNPQGVLILAEKPKLEELSFSDDFILVLDRIQDPGNIGTILRTAIAVGLKEVILINGTVDPFNPKAIRAGMGAQFSLKFSYITNLAELKNIAKLQQRKIWLTTPHQGVSCYAKEFKLANSILVFGEEANGIEDFSIGQKTMIPTLSDIESLNVAQAATIYLFEGLRQRLR
>NZ_CP016635.1|WP_071304239.1|806945_808898_+|BCCT-family-transporter
MQRKKGAYAPVFYPAIVIAAILSLLGVLVPVAFANNIEIIQNLILEKFGWAYILAMSFFVCLCLILMFSRFGDIKLGQDHELPEYTNLSWFAMLFAAGMGIGLMFYGVAEPLNHFLSPPNLSPDSLEMVKQAMNTTFFHWGIQAWSVYAVVGLSLAYFAYRHDLPLLPRSVLYPILGDKIYGVIGHAIDIFAILGTLFGVATSLGFGAMQVSSGISFLTGIADTQNMQVLYIIIIVALATISVALGLDKGIKALSNLNIVLAILLLAFILFLGNTAGLMRDYIQNIGYYLSTIVNQTFNLYAYNQDNQQWLKKWTLFYWGWWIAWSPFVGMFIAKVSKGRTIRQFIIGVLFIPVGFTFLWMTVFGNSAIEIVMTGKAQDLINAANNNIPVALFEFLQHFPFATILSILAVCLVVTFFVTSADSGALVIDILATGNAQASITVQRIAWSVLGGFLAISLILVGGLQALQSATIISAFPLLFILFLMAISLIKSLRLDYLRIKSIQTHSTVVQYVKADTSWQKRLSAIAAKPTKTQAIEFLQQVVTPAVLEVATEMQKNAINTEITKDDEHVQLIIRIESGDDFVYSVMLRSYQTKADNDTYNRVEVLLGHGGQYYDIIGYSKEQVIADIINQYDKHLHYLHLAVADKDIVN
>NZ_CP016635.1|WP_014549651.1|808890_809367_-|tryptophan-rich-sensory-protein
MSQFKITNLISLVLFIIVILTIGYFVGMITSINIPSWFIYLESPFFAPPNWVFAPVWTILYIMIAISGWLIFQQHQLKEKTFIVYVIQLGLNFLWSFIFFCWHNIDLALLEMSILWVFVAWNIIIFRQINNLAGYLLVPYLLWISFAWILNFSYAVLN
>NZ_CP016635.1|WP_003033621.1|809495_810350_+|bifunctional-methionine-sulfoxide-reductase-B/A-protein
MLKTKSLTPHEYDIIINKATEKPFTGRYNDLDQKGVYICRNCGTPLFRADSKFISACGWPSYDIHIDNNVKQLPDADGRRTEILCNNCDGHLGHIFHGEGYTKLNTRYCVNSACVDFIPIEDFGTTEEIIVAAGCFWGVEYYMKKLPGVLFAESGYCGGDQPYPDYKKVCQGDTGYLEVVRVIFDTSKVSLQQVLKYFFEIHDFEQVDGQGPDIGEQYKSAIFYYDDKQKQIAEDLKQILAQKGYKVATEIRAMKPYYVAEDYHLDYYMKKGTLPYCHSHKKIF

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Crispr_ID: NZ_CP016635_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016635_2

1535075-1536785

TypeV-A,TypeI-A

V-A

Consensus_repeat	Method
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CRISPRCasFinder
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CRT
TATCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACATT	PILER-CR
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	PILER-CR

26 spacers

csa3,cas2,cas1,cas4,cas12a

The CRISPR arrays of NZ_CP016635_2

>merge|NZ_CP016635|2|1535075-1536785|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
AATAATATATAGGAAAATTATTTAAAGTTCTTAGACCTATACATTGCTTAATGATAAGCCAATATCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACATTTATTCAGATCGAAATTAACACTCATAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCGATACCAGGAGTTAAGAGAAGATGTTTCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTTTCAATCTCGCCAATTATTCTTTTTTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGATAGTTTAGGATGCAGAAATATATTTGATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACAATCGCATATATTTTATTGTGGTCTCCAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTATCAGAAAAAGCTAGAGAGATACTAGAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACATATAGTATCTACGGGTCTATATCATTTAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGATAAAATGACAAAAGAAGCAGCGATAACATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTAATTTTCTATCTTTAGATTTATTATATTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCTGCTATGCTTACGTAGTCTCCGGCTATATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTGTAACTGAGCCGTGCAACAATAATTCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACAGATTAGAATTGAATCTTATTTCCCTTTGAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGTTGTTCCATTTTGGAACACATAGTCAATATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACAATACTACTTTCATCTAAAGCAACTCCGCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACATAATAAAAAACTCACCATCACGCAGATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACACCTCAAAAACGATATTTCAGCTACATCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTGGAATAAAAAGGTAAAACACATACAAAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCTCTACACTAAGCCGACTCTTAAGCAAGAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTGACAATGGTCGTCCAATGGCTAACAAGATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACACTAAAAAAGAACCAGTAGCCCTAAAGCTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGAGCGTAAAAACGTTCGCATGGCTTTCTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTAAATACAAACACCATTCTAATTCAAGTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTGAGGTGCCACAAAGGTGCCAAGAGTCTAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCCCACAAGATGAAGAATCACAACAATAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACACAATAAATTTAATAATACACATGAAACACATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC

>NZ_CP016635|2|2|1535075-1536785|CRISPRCasFinder
AATAATATATAGGAAAATTATTTAAAGTTCTTAGAC	CTATACATTGCTTAATGATAAGCCAATATC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATTTATTCAGATCGAAATTAACACTCATA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CGATACCAGGAGTTAAGAGAAGATGTTTC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TTTCAATCTCGCCAATTATTCTTTTTT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GATAGTTTAGGATGCAGAAATATATTTG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AATCGCATATATTTTATTGTGGTCTCCA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TATCAGAAAAAGCTAGAGAGATACTAGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATATAGTATCTACGGGTCTATATCATTTA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GATAAAATGACAAAAGAAGCAGCGATAAC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TAATTTTCTATCTTTAGATTTATTATATT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CTGCTATGCTTACGTAGTCTCCGGCTAT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGTAACTGAGCCGTGCAACAATAATTC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AGATTAGAATTGAATCTTATTTCCCTTTGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GTTGTTCCATTTTGGAACACATAGTCAAT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AATACTACTTTCATCTAAAGCAACTCCGC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATAATAAAAAACTCACCATCACGCAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACCTCAAAAACGATATTTCAGCTACATC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGGAATAAAAAGGTAAAACACATACAAA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CTCTACACTAAGCCGACTCTTAAGCAAGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGACAATGGTCGTCCAATGGCTAACAAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACTAAAAAAGAACCAGTAGCCCTAAAGCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GAGCGTAAAAACGTTCGCATGGCTTTCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TAAATACAAACACCATTCTAATTCAAGT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGAGGTGCCACAAAGGTGCCAAGAGTCTA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CCCACAAGATGAAGAATCACAACAATA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACAATAAATTTAATAATACACATGAAACAC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC

>NZ_CP016635|2|2|1535075-1536785|CRT
AATAATATATAGGAAAATTATTTAAAGTTCTTAGAC	CTATACATTGCTTAATGATAAGCCAATATC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATTTATTCAGATCGAAATTAACACTCATA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CGATACCAGGAGTTAAGAGAAGATGTTTC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TTTCAATCTCGCCAATTATTCTTTTTT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GATAGTTTAGGATGCAGAAATATATTTG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AATCGCATATATTTTATTGTGGTCTCCA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TATCAGAAAAAGCTAGAGAGATACTAGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATATAGTATCTACGGGTCTATATCATTTA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GATAAAATGACAAAAGAAGCAGCGATAAC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TAATTTTCTATCTTTAGATTTATTATATT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CTGCTATGCTTACGTAGTCTCCGGCTAT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGTAACTGAGCCGTGCAACAATAATTC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AGATTAGAATTGAATCTTATTTCCCTTTGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GTTGTTCCATTTTGGAACACATAGTCAAT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AATACTACTTTCATCTAAAGCAACTCCGC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATAATAAAAAACTCACCATCACGCAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACCTCAAAAACGATATTTCAGCTACATC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGGAATAAAAAGGTAAAACACATACAAA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CTCTACACTAAGCCGACTCTTAAGCAAGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGACAATGGTCGTCCAATGGCTAACAAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACTAAAAAAGAACCAGTAGCCCTAAAGCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GAGCGTAAAAACGTTCGCATGGCTTTCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TAAATACAAACACCATTCTAATTCAAGT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGAGGTGCCACAAAGGTGCCAAGAGTCTA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CCCACAAGATGAAGAATCACAACAATA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACAATAAATTTAATAATACACATGAAACAC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC

>NZ_CP016635|2|2|1535137-1535309|PILER-CR
TATCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACATT	TATTCAGATCGAAATTAACACT
CATAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCGA	TACCAGGAGTTAAGAGAAGATGTTT
CATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTTTCAATCTCGCCAATTATTCTTTTTTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGATAGTTTAGGATGCAGAAATATATTTGATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACAATCGCATATATTTTATTGTGGTCTCCAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTATCAGAAAAAGCTAGAGAGATACTAGAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACATATAGTATCTACGGGTCTATATCATTTAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGATAAAATGACAAAAGAAGCAGCGATAACATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTAATTTTCTATCTTTAGATTTATTATATTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCTGCTATGCTTACGTAGTCTCCGGCTATATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTGTAACTGAGCCGTGCAACAATAATTCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AGATTAGAATTGAATCTTATTTCCCTTTGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GTTGTTCCATTTTGGAACACATAGTCAAT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AATACTACTTTCATCTAAAGCAACTCCGC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATAATAAAAAACTCACCATCACGCAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACCTCAAAAACGATATTTCAGCTACATC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGGAATAAAAAGGTAAAACACATACAAA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CTCTACACTAAGCCGACTCTTAAGCAAGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGACAATGGTCGTCCAATGGCTAACAAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACTAAAAAAGAACCAGTAGCCCTAAAGCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GAGCGTAAAAACGTTCGCATGGCTTTCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TAAATACAAACACCATTCTAATTCAAGT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGAGGTGCCACAAAGGTGCCAAGAGTCTA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CCCACAAGATGAAGAATCACAACAATA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACAATAAATTTAATAATACACATGAAACAC


>NZ_CP016635|2|3|1535848-1536785|PILER-CR
	TATTCAGATCGAAATTAACACT
CATAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCGA	TACCAGGAGTTAAGAGAAGATGTTT
CATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTTTCAATCTCGCCAATTATTCTTTTTTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGATAGTTTAGGATGCAGAAATATATTTGATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACAATCGCATATATTTTATTGTGGTCTCCAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTATCAGAAAAAGCTAGAGAGATACTAGAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACATATAGTATCTACGGGTCTATATCATTTAATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACGATAAAATGACAAAAGAAGCAGCGATAACATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTAATTTTCTATCTTTAGATTTATTATATTATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACCTGCTATGCTTACGTAGTCTCCGGCTATATCTACAACAGTAGAAATTATTTAAAGTTCTTAGACTGTAACTGAGCCGTGCAACAATAATTCATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AGATTAGAATTGAATCTTATTTCCCTTTGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GTTGTTCCATTTTGGAACACATAGTCAAT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	AATACTACTTTCATCTAAAGCAACTCCGC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ATAATAAAAAACTCACCATCACGCAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACCTCAAAAACGATATTTCAGCTACATC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGGAATAAAAAGGTAAAACACATACAAA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CTCTACACTAAGCCGACTCTTAAGCAAGA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGACAATGGTCGTCCAATGGCTAACAAG
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACTAAAAAAGAACCAGTAGCCCTAAAGCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	GAGCGTAAAAACGTTCGCATGGCTTTCT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TAAATACAAACACCATTCTAATTCAAGT
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	TGAGGTGCCACAAAGGTGCCAAGAGTCTA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	CCCACAAGATGAAGAATCACAACAATA
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC	ACAATAAATTTAATAATACACATGAAACAC
ATCTACAACAGTAGAAATTATTTAAAGTTCTTAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016635.1\|WP_003015040.1\|1531684_1532371_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810
NZ_CP016635.1\|WP_071304623.1\|1534131_1534650_-\|DUF2892-domain-containing-protein	unknown	unknown	gnl\|CDD\|223680
NZ_CP016635.1\|WP_003034654.1\|1544083_1544773_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP016635.1\|WP_071304627.1\|1546555_1547500_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NZ_CP016635.1\|WP_080558945.1\|1530320_1530941_+\|2OG-Fe(II)-oxygenase	unknown	unknown	gnl\|CDD\|379309
NZ_CP016635.1\|WP_080542741.1\|1529145_1529613_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016635.1\|WP_071304624.1\|1538847_1542750_-\|type-V-CRISPR-associated-protein-Cas12a/Cpf1	cas12a	cas12a_cpf1_CAS-V-A	gnl\|CDD\|275131
NZ_CP016635.1\|WP_003034639.1\|1537177_1538182_-\|type-V-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|213942
NZ_CP016635.1\|WP_071304626.1\|1544842_1545478_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NZ_CP016635.1\|WP_071304625.1\|1543357_1544074_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016635.1\|WP_003034660.1\|1545474_1546365_-\|NAD(+)-kinase	unknown	unknown	gnl\|CDD\|179257
NZ_CP016635.1\|WP_014550090.1\|1530933_1531683_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP016635.1\|WP_080558969.1\|1538185_1538722_-\|type-V-CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|213941
NZ_CP016635.1\|WP_014550092.1\|1536924_1537197_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NZ_CP016635.1\|WP_003018167.1\|1534715_1535015_-\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP016635.1\|WP_003022238.1\|1529834_1530281_+\|YcgN-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|235356
NZ_CP016635.1\|WP_081353790.1\|1532415_1534110_-\|SidA/IucD/PvdA-family-monooxygenase	unknown	unknown	gnl\|CDD\|163244
NZ_CP016635.1\|WP_071304621.1\|1528070_1528496_-\|transcription-antitermination-factor-NusB	unknown	unknown	gnl\|CDD\|273891
NZ_CP016635.1\|WP_003034650.1\|1542837_1543353_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|225695
NZ_CP016635.1\|WP_003025316.1\|1528682_1529084_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP016635.1\|WP_003015040.1\|1531684_1532371_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	3.1463e-85
NZ_CP016635.1\|WP_071304623.1\|1534131_1534650_-\|DUF2892-domain-containing-protein	gnl\|CDD\|223680	COG0607, PspE, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	4.14079e-19
NZ_CP016635.1\|WP_003034654.1\|1544083_1544773_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.34669e-87
NZ_CP016635.1\|WP_071304627.1\|1546555_1547500_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	7.2921e-82
NZ_CP016635.1\|WP_080558945.1\|1530320_1530941_+\|2OG-Fe(II)-oxygenase	gnl\|CDD\|379309	pfam13640, 2OG-FeII_Oxy_3, 2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily.	1.29174e-23
NZ_CP016635.1\|WP_071304624.1\|1538847_1542750_-\|type-V-CRISPR-associated-protein-Cas12a/Cpf1	gnl\|CDD\|275131	TIGR04330, conserved_hypothetical_protein, CRISPR-associated protein Cpf1, subtype PREFRAN. This family is the long protein of a novel CRISPR subtype, PREFRAN, which is most common in Prevotella and Francisella, although widely distributed. The PREFRAN type has Cas1, Cas2, and Cas4, but lacks the helicase Cas3 and endonuclease Cas3-HD.	0
NZ_CP016635.1\|WP_003034639.1\|1537177_1538182_-\|type-V-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|213942	TIGR04329, hypothetical_protein_SbacW_07302_partial, CRISPR-associated endonuclease Cas1, subtype PREFRAN. Members of this family are the Cas1 endonuclease of a novel CRISPR subtype, PREFRAN, found in Prevotella bryantii B14, Prevotella disiens FB035-09AN, Francisella tularensis subsp. novicida, Francisella philomiragia, Butyrivibrio proteoclasticus B316, Helcococcus kunzii ATCC 51366, etc.	0
NZ_CP016635.1\|WP_071304626.1\|1544842_1545478_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.18314e-20
NZ_CP016635.1\|WP_003034660.1\|1545474_1546365_-\|NAD(+)-kinase	gnl\|CDD\|179257	PRK01231, ppnK, NAD(+) kinase.	4.0724e-91
NZ_CP016635.1\|WP_014550090.1\|1530933_1531683_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.79023e-31
NZ_CP016635.1\|WP_080558969.1\|1538185_1538722_-\|type-V-CRISPR-associated-protein-Cas4	gnl\|CDD\|213941	TIGR04328, hypothetical_protein_HMPREF9709_01098, CRISPR-associated protein Cas4, subtype PREFRAN. Members of this family are the Cas4 protein of a novel CRISPR subtype, PREFRAN, found in Prevotella bryantii B14, Prevotella disiens FB035-09AN, Francisella tularensis subsp. novicida, Francisella philomiragia, Butyrivibrio proteoclasticus B316, Helcococcus kunzii ATCC 51366, etc.	1.91061e-102
NZ_CP016635.1\|WP_014550092.1\|1536924_1537197_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	4.95236e-13
NZ_CP016635.1\|WP_003018167.1\|1534715_1535015_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	3.12712e-19
NZ_CP016635.1\|WP_003022238.1\|1529834_1530281_+\|YcgN-family-cysteine-cluster-protein	gnl\|CDD\|235356	PRK05170, PRK05170, YcgN family cysteine cluster protein.	6.61276e-69
NZ_CP016635.1\|WP_081353790.1\|1532415_1534110_-\|SidA/IucD/PvdA-family-monooxygenase	gnl\|CDD\|163244	TIGR03385, Coenzyme_A_disulfide_reductase, CoA-disulfide reductase. Members of this protein family are CoA-disulfide reductase (EC 1.8.1.14), as characterized in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi, and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. [Cellular processes, Detoxification].	5.98382e-139
NZ_CP016635.1\|WP_071304621.1\|1528070_1528496_-\|transcription-antitermination-factor-NusB	gnl\|CDD\|273891	TIGR01951, nusB, transcription antitermination factor NusB. A transcription antitermination complex active in many bacteria was designated N-utilization substance (Nus) in E. coli because of its interaction with phage lambda protein N. This model represents NusB. Other components are NusA and NusG. NusE is, in fact, ribosomal protein S10. [Transcription, Transcription factors].	1.78797e-38
NZ_CP016635.1\|WP_003034650.1\|1542837_1543353_-\|N-acetyltransferase	gnl\|CDD\|225695	COG3153, COG3153, Predicted acetyltransferase [General function prediction only].	4.99602e-39

>NZ_CP016635.1|WP_003018167.1|1534715_1535015_-|helix-turn-helix-transcriptional-regulator
MDLMQMKDNASKASSLLKAISHESRLLILCLLLRREMTVGELAEYSSLSQSAFSQHLSVLRNNGLVKCRKEAQNVYYSINDPSVTKILEALYSIYCGDK
>NZ_CP016635.1|WP_071304623.1|1534131_1534650_-|DUF2892-domain-containing-protein
MNKVEKISVKQFLDLQKKEKVKLIDIRTPAEHSRECIDCAENILVDDIYDADIKPDEVVVLHCQSGNRTNQAASKVSGLNAKRVYLLDGGINAWKQHKQPTQKNVKEPLPIMRQVQIIVGFLVLLGVVLSFTVSQYFAILSGFFGAGLLFAGLTGTCGLAVMLEFLPYNRKK
>NZ_CP016635.1|WP_081353790.1|1532415_1534110_-|SidA/IucD/PvdA-family-monooxygenase
MMTKKYLIVGGVAAGASAAARLRRLDESAEIIMFEKGPHVSFSNCGLPYHLGGYIEPAEKLILMTPEKFDKQYNIDARTNSEVIAIDRINKLVTVINHHSGDKYSESYDKLILAVGAKPIVPPFKGLETIEHFILRNVVDVKKIHQAVFDKQNPIKDITVIGAGFIGVEVAENLKERGFNVTIIEMANQIMRPFDYEMAKFLEKELLDNGVNLLLGEKVVGFESDKVLLESGKEIKTDLAILAIGVAPDTNFLKEVGIDLAKTGHILVNDNYQTSDENIYAAGDAILVKNALTAQDFNLPLAGPANKQGRLIADHINGHKVVNKGYIGSSIIQIFNYTGAATGLNEAWIKFHNLDIDYEVAYTAPFDRVSIMPNAVNVFTKILFEKNTGKLLGAQVIGRGIVDKRADVFATAIKAGMTVEDLQDLELCYAPPYSTGKDIVNHTGYVASNLLKGDFKQVAFTKVEELLAQNAQIIDVREIGETRRGMLTNAKNIPLSEIRARLAEIDKNQPVYVHCQTGQRSYNVVLMLQQHGYDVYNIAGGYIMISHYYDTIVHMTGKEISFTR
>NZ_CP016635.1|WP_003015040.1|1531684_1532371_-|MBL-fold-metallo-hydrolase
MIFRQLIDRDTYTYTYILACEQTRQAVIIDSVRFNVNQYLKLLKELDLKLIYAIDTHVHADHVTAAGILRKETGCDIVIGGESKAECATKKVFDGDILEFGNYQLKALYTPGHTDDSYCFITENMLFTGDTLLIRGSGRTDFQNGDSYAAYDSIMNKLMTLPGSTIIYPGHDYNGITSSSVAEERQNNPRLKVKSPDEYAKLMADLKLPPPNYIDIAVPANLKCGIEE
>NZ_CP016635.1|WP_014550090.1|1530933_1531683_-|sulfite-exporter-TauE/SafE-family-protein
MFLIIFGFICGIALGLTGGGGSILAVPLLTYGVGLEFHSAVMISLLVVGFTAIFGLIVNYKQRDIDYIAAVIMIITGVIFAPIGSYISQGLSDKLLMLSFSILMILIGVWSLVKVKLMSGSEKSIYKNITPRFIVALLISGGIVGTLTGFFGVGGGFLIVPALVFITAMPIKRAINTSLLVIFVVSISGFISHYDKTSMNWYIASMFIVGGAIGMFLATRVKKSLNDKVLQTIFAIMLVILGVVIYLIN
>NZ_CP016635.1|WP_080558945.1|1530320_1530941_+|2OG-Fe(II)-oxygenase
MGIIMSDLIAINPFYEKIINDYLNKDFCIIDNWLTTDETDKLRQQLEELYQANYFKKSAVGNRLNENLERSIRSDFIFWLDETKYAQVFFEKINSFIEYINKTCFAGIVTKEFHYAVYPQGSFYKKHIDTFQNDDRRTISVVCYLNQDWQDCFGGQLKLYFKDQTLEVFPTDGKIVLFDSKSIEHEVLPVLTENKRLSITGWLKTN
>NZ_CP016635.1|WP_003022238.1|1529834_1530281_+|YcgN-family-cysteine-cluster-protein
MSKWWQQIDLKDMSSEQWESICDRCGLCCLNKLQDDETDEVYYTRVSCKLLDIGKCQCSMYQKRKQLVPECVNLTYKQLKNHAHKWLPNSCSYKLLFEGKDLPDWHHLNTGSTEEMHKQKKSAKHFAISEYELDVDEYLEDFIIKIDN
>NZ_CP016635.1|WP_080542741.1|1529145_1529613_+|hypothetical-protein
MSGCASSGPQQPNLTPLQIQLMQTKVFNVDLRTAFDATVTVMQNLGYIIQDANFNSGIITAKSTQTANFWGDSEYTEATAFIQPYRQSNKNSSIRINFVVYNSMPNPNQGGTPINTSSAILDPQAYENAFAKIQQQIFVQTGISPVLTQPIQQVS
>NZ_CP016635.1|WP_003025316.1|1528682_1529084_+|hypothetical-protein
MKFNIICMLGLAFILSSCVSNTNPENVGFVKTPYTSGNVSLTLKKGVTTKDQVINAFGSPNIVTQNADGESVWTYQTNATVENNAARDGFLTLLITGENTEESGFMQSQKTMTIIITFKGNVVSDYKSLSTNF
>NZ_CP016635.1|WP_071304621.1|1528070_1528496_-|transcription-antitermination-factor-NusB
MKTTARARNNARLYAVQALYQKKIADNTFSELKLQYYADNADRHYTDWDLFYRLIDAVKTNQDTIDKYIKENSSNGVESINYVDYAVLQVAIAELIECLENPYQVIIKEYVEICYSMGTEEGYKFINAVLQNLAKSIRGEE
>NZ_CP016635.1|WP_014550092.1|1536924_1537197_-|CRISPR-associated-endonuclease-Cas2
MLIVSYDFSNNKVRAKFAKFLESYGVRLQYSVFELKYSKRMLDLILAEIENHYVPLFTNADSVLIFNAPDKDVIKYGYAIHREQEVVFID
>NZ_CP016635.1|WP_003034639.1|1537177_1538182_-|type-V-CRISPR-associated-endonuclease-Cas1
MFSKNDIESKNIVFVNIFDGVKLSLSLGNIVIKDKETDEVKTKLSVHKVLALFIVGNMTMTSQLLETCKKNAIQLVFMKNSFRPYLCFGDIAEANFLARYKQYSVVEQDISLARIFITSKIRNQHNLVKSLRDKTPEQQEIVKKNKQLIAELENTTSLAELMGIEGNVAKNFFKGFYGHLDSWQGRKPRIKQDPYNVVLDLGYSMLFNFVECFLRLFGFDLYKGFCHQTWYKRKSLVCDFVEPFRCIVDNQVRKSWNLGQFSVEDFGCKNEQFYIKKDKTKDYSKILFAEIISYKLEIFEYVREFYRAFMRDKEIAEYPIFCYETRRVYVDSQL
>NZ_CP016635.1|WP_080558969.1|1538185_1538722_-|type-V-CRISPR-associated-protein-Cas4
MTWLNDFIFCPYSIYLHNIYSNASDTTYYSSSQTKGRDAHKSIDKGIYSTKKDDLIGIDVINHKYGLVGKIDVFHKDKGLLVERKRQIKTIYDGYKYQLYAQYFCLLEMGYDVKAIKFYSMVDNKSYPIAIPTSAELEKFEKHIQTIKQYNPMDNSFRQNIEKCKFCIYANLCDKTDL
>NZ_CP016635.1|WP_071304624.1|1538847_1542750_-|type-V-CRISPR-associated-protein-Cas12a/Cpf1
MSIYQEFVNKYSLSKTLRFELIPQGKTLENIKARGLILDDEKRAKDYKKAKQIIDKYHQFFIEEILSSVCISEDLLQNYSDVYFKLKKSDDDNLQKDFKSAKDSIKKQISKYINDSEKFKNLFNQNLIDAKKGQESDLILWLKQSKDNGIELFKANSDITDIDEALEIIKSFKGWTTYFKGFHENRKNVYSSNDIPTSIIYRIVDDNLPKFLENKAKYESLKDKAPEAINYEQIKKDLAEELTFDIDYKTSEVNQRVFSLDEVFEIANFNNYLNQSGITKFNTIIGGKFVNGENTKRKGINEYINLYSQQINDKTLKKYKMSVLFKQILSDTESKSFVIDKLEDDSDVVTTMQSFYEQIAAFKTVEEKSIKETLSLLFDDLKAQKLDLSKIYFKNDKSLTDLSQQVFDDYSVIGTAVLEYITQQVAPKNLDNPSKKEQDLIAKKTEKAKYLSLETIKLALEEFNKHRDIDKQCRFEEILANFAAIPMIFDEIAQNKDNLAQISIKYQNQGKKDLLQASAEDDVKAIKDLLDQTNNLLHRLKIFHISQSEDKANILDKDEHFYLVFEECYFELANIVPLYNKIRNYITQKPYSDEKFKLNFENSTLANGWDKNKEPDNTAILFIKDDKYYLGVMNKKNNKIFDDKAIKENKGEGYKKIVYKLLPGANKMLPKVFFSAKSIKFYNPSEDILRIRNHSTHTKNGNPQKGYEKFEFNIEDCRKFIDFYKESISKHPEWKDFGFRFSDTQRYNSIDEFYREVENQGYKLTFENISESYIDSVVNQGKLYLFQIYNKDFSAYSKGRPNLHTLYWKALFDERNLQDVVYKLNGEAELFYRKQSIPKKITHPAKEAIANKNKDNPKKESFFEYDLIKDKRFTEDKFFFHCPIKINFKSSGANKFNDEINLLLKEKANDVHILSIDRGERHLAYYTLVDGKGNIIKQDTFNIIGNDRMKTNYHDKLAAIEKDRDSARKDWKKINNIKEMKEGYLSQVVHEIAKLVIEHNAIVVFEDLNFGFKRGRFKVEKQVYQKLEKMLIEKLNYLVFKDNEFDKTGGVLRAYQLTAPFETFKKMGKQTGIIYYVPAGFTSKICPVTGFVNQLYPKYESVSKSQEFFSKFDKICYNLDKGYFEFSFDYKNFGDKAAKGKWTIASFGSRLINFRNSDKNHNWDTREVYPTKELEKLLKDYSIEYGHGECIKAAICGESDKKFFAKLTSILNTILQMRNSKTGTELDYLISPVADVNGNFFDSRQAPKNMPQDADANGAYHIGLKGLMLLDRIKNNQEGKKLNLVIKNEEYFEFVQNRNN
>NZ_CP016635.1|WP_003034650.1|1542837_1543353_-|N-acetyltransferase
MHVKIRYEKLKDQELIYKLISEAFDTGDEEKLVRLLHTDHQSLISLVAETDDSSIIGQAIISKMTAEKDQTLKIYALAPMSVAPKYQHQGIGSKLIEAMIKEAKKNNIDAIFVLGHPSYYPKFGFKPATEYQIKCEYDVPADVFMVLDLSAKLASLKGQTVYYADEFGKIF
>NZ_CP016635.1|WP_071304625.1|1543357_1544074_-|hypothetical-protein
MKIARYKKGFIKASEYNSKLHFDNIFCPDCGKAKVKIVRKADQEPYFVFVQDQQHDELCPRVAKPIQDQKIKELILSDSKKDMSKLNFLVNKNLEKCINLVTKLENNGELKKADELNLMPQKKQQLTEKRIREYAKQDIYTINIVDLSDIDTQQLNNKYCLIYGVAGITLADVGDSKKLFFKADQDSRFSLFVVPSQIKYLDFDKGKRTKFAVFGRFKKVGKFINLEIRSTRDLVIRD
>NZ_CP016635.1|WP_003034654.1|1544083_1544773_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MCDKSKENLRQIKSYVQRAGRVTKKQQQALDNYAAKYLIEYAKDRKLDFTEIFANTNDVVLEIGFGMGGSLVEMALANPAKNYLGIEVHKAGVGNILYEIEHQNIANLVVMSHDAVEILENMIADQSLASIQVYFPDPWHKKKHNKRRLVNQTNIDLFAKKLKVGGVFHYASDWLPYAEEVLELLENDSKYRNLYSGFAPRPEWRPLTKFEKRGQNLDHPISDILFEKI
>NZ_CP016635.1|WP_071304626.1|1544842_1545478_+|LysE-family-translocator
MLIFLTILALQISCLILPGPDFFVTISNSIKFGHKSGIYTASGVASGIFLNTFIVYWFGSLLLYKQPLLFKMLIIIGAAYLAYIAFSLYKSIFTKQQLNPNANQHIKNLDNFDKPSNTKLFLNGAFTNLANAKVLVFFSSMLSLVDGLNSFGKVAIWIAIALTTLVWFCIVATFFGNDKLRQVFFRNIKKIEFISAIFITIFVIVILVELF
>NZ_CP016635.1|WP_003034660.1|1545474_1546365_-|NAD(+)-kinase
MAFKYHKVAIIGKHYKKEVSQMVETLYAYLQQQGLEIIIENDTAADTSLVNIATASLKEIALRCDVAIVVGGDGNFLKASRLLALYSNIPVIGINKGKLGFLTTLAADDNALKNDLYAILKGDSSVTKMSMLKCRVDNNLRAPLEASIALNEIAITASRGLMFGLKVFIDGRYAFDQRGDGLIVSTPTGSTAHAMSAGGPILNPNQNSVVLVPICSHSLNSRPLVISDESVIDIYITDYNDPEPVLSIDGRHDTILKAHQKVTIQKARKKVTVLHTKDYNYYDTLREKLGWSKVLF
>NZ_CP016635.1|WP_071304627.1|1546555_1547500_+|glycosyltransferase-family-2-protein
MDNKDKLTSIIIPVKDEAEGIEHLFARLMPILDKLPTKYELVFINDGSNDNTLELLLEKQKDIPEIAIVDLSRNFGKEAALFAGFANCNGDAAISIDADLQDPPELILEMVQHWLDGYEVVTAVRENRDTDTSTKKHTAGLFYKVMNKISDTKLTPNAGDYRLLNRAAVNAFLELKEKIRFNKGLLTWIGFKEKIVYHAREERAAGQTKWNYWKLFKFSIDGITSFSRAPLEIWSYIGVVVALISFIYGSIIVLKSLLFGVDVPGYPSLVTFILFFSGLQMIGIGMLGSYIGRIFIETKHRPLYIIRQVHRAKE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016635_2	2.28\|1535245\|25\|NZ_CP016635\|PILER-CR	1535245-1535269	25	NC_023026	Francisella novicida strain PA10-7858 plasmid pFNPA10, complete sequence	23205-23229	1	0.96
NZ_CP016635_2	2.3\|1535242\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535242-1535270	29	NC_023026	Francisella novicida strain PA10-7858 plasmid pFNPA10, complete sequence	23201-23229	2	0.931
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	NC_022051	Listeria monocytogenes strain J1926 plasmid, complete sequence	55758-55783	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	CP044431	Listeria monocytogenes strain FDA00006667 plasmid pCFSAN038814, complete sequence	26444-26469	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	NC_022046	Listeria monocytogenes strain J1776 plasmid, complete sequence	55695-55720	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	NC_022047	Listeria monocytogenes strain J1817 plasmid, complete sequence	4686-4711	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	NZ_CP053631	Listeria monocytogenes strain OB040119 plasmid pOB040119, complete sequence	34676-34701	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	NZ_CP053629	Listeria monocytogenes strain OB030029 plasmid pOB030029, complete sequence	34676-34701	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	NZ_CP053633	Listeria monocytogenes strain OB050226 plasmid pOB050226, complete sequence	34672-34697	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	NZ_CP014254	Listeria monocytogenes strain CFSAN023459 plasmid CFSAN023459_02, complete sequence	29365-29390	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	CP044433	Listeria monocytogenes strain FDA00009448 plasmid pCFSAN038814, complete sequence	47986-48011	4	0.846
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	HQ633061	Synechococcus phage S-CBM2, * SEQUENCING IN PROGRESS *, 6 unordered pieces	107474-107499	4	0.846
NZ_CP016635_2	2.25\|1536657\|27\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536657-1536683	27	NZ_LR027875	Staphylococcus aureus strain BPH2056 isolate BPH2056 plasmid 2	22506-22532	4	0.852
NZ_CP016635_2	2.25\|1536657\|27\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536657-1536683	27	NZ_LR027872	Staphylococcus aureus strain BPH2019 isolate BPH2019 plasmid 3	24482-24508	4	0.852
NZ_CP016635_2	2.25\|1536657\|27\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536657-1536683	27	NC_014369	Staphylococcus aureus plasmid pSK1, complete sequence	1079-1105	4	0.852
NZ_CP016635_2	2.25\|1536657\|27\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536657-1536683	27	NC_013393	Staphylococcus epidermidis plasmid pSK105, complete sequence	6848-6874	4	0.852
NZ_CP016635_2	2.4\|1535307\|27\|NZ_CP016635\|CRISPRCasFinder,CRT	1535307-1535333	27	NC_018878	Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence	73415-73441	5	0.815
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	LR721752	Aliivibrio wodanis 06/09/160 plasmid 1 complete sequence	36078-36105	5	0.821
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_CP044981	Bacillus thuringiensis strain BT62 plasmid pBT62C, complete sequence	2576-2604	5	0.828
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_CP020751	Bacillus mycoides strain Gnyt1 plasmid unnamed8, complete sequence	6898-6926	5	0.828
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_CP023822	Escherichia coli strain 7/2 plasmid p7_2.2, complete sequence	34987-35015	5	0.828
NZ_CP016635_2	2.16\|1536080\|26\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536080-1536105	26	AP014249	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S36-C17, * SEQUENCING IN PROGRESS *	10881-10906	5	0.808
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	CP046512	Bacillus cereus strain JHU plasmid p1, complete sequence	335857-335884	5	0.821
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP023246	Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence	346967-346994	5	0.821
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	384860-384887	5	0.821
NZ_CP016635_2	2.21\|1536399\|29\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536399-1536427	29	MF448557	Lactococcus phage 37201, complete genome	17509-17537	5	0.828
NZ_CP016635_2	2.21\|1536399\|29\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536399-1536427	29	NC_049401	Lactococcus phage 38503, complete genome	13705-13733	5	0.828
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	AP013581	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C23-MedDCM-OCT-S23-C56, * SEQUENCING IN PROGRESS *	12686-12714	6	0.793
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	MK250029	Prevotella phage Lak-C1, complete genome	84889-84917	6	0.793
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	MK250016	Prevotella phage Lak-A1, complete genome	107155-107183	6	0.793
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	MK250019	Prevotella phage Lak-A2, complete genome	30043-30071	6	0.793
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_AP017296	Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence	140131-140159	6	0.793
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NC_006869	Bacillus mycoides pSin9.7 plasmid	7680-7708	6	0.793
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	94801-94829	6	0.793
NZ_CP016635_2	2.17\|1536142\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536142-1536169	28	NZ_CP017078	Novosphingobium resinovorum strain SA1 plasmid pSA3, complete sequence	113576-113603	6	0.786
NZ_CP016635_2	2.17\|1536142\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536142-1536169	28	MK448732	Streptococcus phage Javan331, complete genome	33486-33513	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024318	Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-1	41703-41730	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024207	Borrelia miyamotoi strain Izh-5 plasmid pIzh5-1	41774-41801	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024335	Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-1	41710-41737	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024353	Borrelia miyamotoi strain Izh-16 plasmid pIzh16-1	41714-41741	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024325	Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-6	8805-8832	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024392	Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp70, complete sequence	28338-28365	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024209	Borrelia miyamotoi strain Izh-5 plasmid pIzh5-2	10705-10732	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP040828	Borrelia miyamotoi strain Izh-4 plasmid pIzh4-cp30-2, complete sequence	25141-25168	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024373	Borrelia miyamotoi strain Izh-14 plasmid pIzh14-1	28374-28401	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024381	Borrelia miyamotoi strain Izh-14 plasmid pIzh14-6	3189-3216	6	0.786
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP024382	Borrelia miyamotoi strain Izh-14 plasmid pIzh14-7	16999-17026	6	0.786
NZ_CP016635_2	2.22\|1536464\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536464-1536491	28	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	592649-592676	6	0.786
NZ_CP016635_2	2.22\|1536464\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536464-1536491	28	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	453076-453103	6	0.786
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NC_013393	Staphylococcus epidermidis plasmid pSK105, complete sequence	5080-5109	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_LR027875	Staphylococcus aureus strain BPH2056 isolate BPH2056 plasmid 2	695-724	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_LR027872	Staphylococcus aureus strain BPH2019 isolate BPH2019 plasmid 3	695-724	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NC_014369	Staphylococcus aureus plasmid pSK1, complete sequence	2844-2873	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	KX879627	Campylobacter phage vB_CjeM_Los1, complete genome	115547-115576	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	MH107028	Campylobacter phage CP39, partial genome	50619-50648	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NC_015464	Campylobacter phage NCTC12673, complete genome	28111-28140	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	KF148616	Campylobacter phage CP8, complete genome	117151-117180	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NC_016562	Campylobacter phage CPX, complete genome	116915-116944	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	KX236333	Campylobacter phage PC14, complete genome	63107-63136	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	JX569801	Campylobacter phage CP30A, complete genome	30960-30989	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	KX229736	Campylobacter phage PC5, complete genome	118448-118477	6	0.8
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NC_042112	Campylobacter phage CP81, complete genome	11740-11769	6	0.8
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	KM652554	Streptomyces phage Jay2Jay, complete genome	81099-81126	7	0.75
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	MF358541	Streptomyces phage Warpy, complete genome	80606-80633	7	0.75
NZ_CP016635_2	2.15\|1536015\|29\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536015-1536043	29	KJ489402	Bacillus phage Riley, complete genome	123949-123977	7	0.759
NZ_CP016635_2	2.15\|1536015\|29\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536015-1536043	29	MF765814	Bacillus phage Taffo16, complete genome	126190-126218	7	0.759
NZ_CP016635_2	2.15\|1536015\|29\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536015-1536043	29	NC_022088	Bacillus phage Troll, complete genome	127094-127122	7	0.759
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NC_010010	Bacillus megaterium QM B1551 plasmid pBM300, complete sequence	11421-11448	7	0.75
NZ_CP016635_2	2.18\|1536206\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536206-1536233	28	NZ_CP028889	Borrelia turcica IST7 plasmid lp35, complete sequence	9954-9981	7	0.75
NZ_CP016635_2	2.20\|1536335\|28\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536335-1536362	28	NC_017543	Paenibacillus polymyxa M1 plasmid pPPM1a, complete sequence	74890-74917	7	0.75
NZ_CP016635_2	2.25\|1536657\|27\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536657-1536683	27	NC_011973	Bacillus cereus Q1 plasmid pBc239, complete sequence	177103-177129	7	0.741
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	42775-42804	7	0.767
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_CP026601	Clostridiaceae bacterium 14S0207 plasmid unnamed1, complete sequence	41361-41390	7	0.767
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	4235-4264	7	0.767
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	KX961629	Bacillus phage BJ4, complete genome	109739-109766	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	MN038176	Bacillus phage Phireball, complete genome	110584-110611	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	KU160494	Vibrio phage vB_VmeM-32, complete genome	106835-106862	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	MF288920	Bacillus phage Zainny, complete genome	110652-110679	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	KU737344	Bacillus phage Nigalana, complete genome	111425-111452	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	KJ489399	Bacillus phage Hakuna, complete genome	108823-108850	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	NC_031027	Bacillus phage SageFayge, complete genome	110449-110476	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	KX349902	Bacillus phage Kida, complete genome	110513-110540	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	NC_031024	Bacillus phage Belinda, complete genome	110718-110745	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	MF288917	Bacillus phage PPIsBest, complete genome	110857-110884	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	MN038179	Bacillus phage ALPS, complete genome	110735-110762	8	0.714
NZ_CP016635_2	2.7\|1535498\|28\|NZ_CP016635\|CRISPRCasFinder,CRT	1535498-1535525	28	KU737351	Bacillus phage NotTheCreek, complete genome	110894-110921	8	0.714
NZ_CP016635_2	2.9\|1535627\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535627-1535655	29	NZ_CP020504	Serratia marcescens strain 95 plasmid unnamed3, complete sequence	5787-5815	8	0.724
NZ_CP016635_2	2.9\|1535627\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535627-1535655	29	NZ_CP026402	Escherichia coli strain ECONIH4 plasmid pECO-e618, complete sequence	9971-9999	8	0.724
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	70798-70826	8	0.724
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NC_010933	Bacillus cereus strain G9241 plasmid pBC210, complete sequence	113121-113149	8	0.724
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_CP009591	Bacillus cereus G9241 plasmid pBC210, complete sequence	33146-33174	8	0.724
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	MH552532	Siphoviridae sp. isolate ctbf3, complete genome	11694-11722	8	0.724
NZ_CP016635_2	2.10\|1535692\|29\|NZ_CP016635\|CRISPRCasFinder,CRT	1535692-1535720	29	NZ_CP009940	Bacillus cereus strain 03BB87 plasmid pBCX01, complete sequence	74462-74490	8	0.724
NZ_CP016635_2	2.14\|1535950\|29\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1535950-1535978	29	AP013559	Uncultured Mediterranean phage uvMED isolate uvMED-CGR-C43-MedDCM-OCT-S32-C95, * SEQUENCING IN PROGRESS *, 2 ordered pieces	16571-16599	8	0.724
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NC_012219	Clostridium botulinum plasmid pC2C203U28 DNA, complete sequence, serotype: type C, strain: (C)-203U28	95401-95430	8	0.733
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_CP029459	Clostridium novyi strain 150557 plasmid pCN1, complete sequence	4467-4496	8	0.733
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_CP029459	Clostridium novyi strain 150557 plasmid pCN1, complete sequence	124299-124328	8	0.733
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NZ_KR611317	Rickettsia endosymbiont of Ixodes pacificus strain Humboldt plasmid pREIP, complete sequence	35335-35364	8	0.733
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	MT774398	CrAssphage cr60_1, complete genome	27091-27120	8	0.733
NZ_CP016635_2	2.26\|1536720\|30\|NZ_CP016635\|CRISPRCasFinder,CRT,PILER-CR	1536720-1536749	30	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	37925-37954	9	0.7

1. spacer 2.28|1535245|25|NZ_CP016635|PILER-CR matches to NC_023026 (Francisella novicida strain PA10-7858 plasmid pFNPA10, complete sequence) position: , mismatch: 1, identity: 0.96

cgataccaggagttaagagaagatg	CRISPR spacer
agataccaggagttaagagaagatg	Protospacer
 ************************

2. spacer 2.3|1535242|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NC_023026 (Francisella novicida strain PA10-7858 plasmid pFNPA10, complete sequence) position: , mismatch: 2, identity: 0.931

cgataccaggagttaagagaagatgtttc	CRISPR spacer
agataccaggagttaagagaagatgtttt	Protospacer
 ***************************.

3. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_022051 (Listeria monocytogenes strain J1926 plasmid, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

4. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to CP044431 (Listeria monocytogenes strain FDA00006667 plasmid pCFSAN038814, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

5. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_022046 (Listeria monocytogenes strain J1776 plasmid, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

6. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_022047 (Listeria monocytogenes strain J1817 plasmid, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

7. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053631 (Listeria monocytogenes strain OB040119 plasmid pOB040119, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

8. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053629 (Listeria monocytogenes strain OB030029 plasmid pOB030029, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

9. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053633 (Listeria monocytogenes strain OB050226 plasmid pOB050226, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

10. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014254 (Listeria monocytogenes strain CFSAN023459 plasmid CFSAN023459_02, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

11. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to CP044433 (Listeria monocytogenes strain FDA00009448 plasmid pCFSAN038814, complete sequence) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
agtttaataaactcaccatcacgcag	Protospacer
*   *** ******************

12. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to HQ633061 (Synechococcus phage S-CBM2, *** SEQUENCING IN PROGRESS ***, 6 unordered pieces) position: , mismatch: 4, identity: 0.846

ataataaaaaactcaccatcacgcag	CRISPR spacer
ataataaaaaacccaccatcaaggtg	Protospacer
************.******** *  *

13. spacer 2.25|1536657|27|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR027875 (Staphylococcus aureus strain BPH2056 isolate BPH2056 plasmid 2) position: , mismatch: 4, identity: 0.852

cccacaagatgaagaatcacaacaata	CRISPR spacer
tcaacaagatgaaaaatcacaacaaca	Protospacer
.* **********.***********.*

14. spacer 2.25|1536657|27|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR027872 (Staphylococcus aureus strain BPH2019 isolate BPH2019 plasmid 3) position: , mismatch: 4, identity: 0.852

cccacaagatgaagaatcacaacaata	CRISPR spacer
tcaacaagatgaaaaatcacaacaaca	Protospacer
.* **********.***********.*

15. spacer 2.25|1536657|27|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_014369 (Staphylococcus aureus plasmid pSK1, complete sequence) position: , mismatch: 4, identity: 0.852

cccacaagatgaagaatcacaacaata	CRISPR spacer
tcaacaagatgaaaaatcacaacaaca	Protospacer
.* **********.***********.*

16. spacer 2.25|1536657|27|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_013393 (Staphylococcus epidermidis plasmid pSK105, complete sequence) position: , mismatch: 4, identity: 0.852

cccacaagatgaagaatcacaacaata	CRISPR spacer
tcaacaagatgaaaaatcacaacaaca	Protospacer
.* **********.***********.*

17. spacer 2.4|1535307|27|NZ_CP016635|CRISPRCasFinder,CRT matches to NC_018878 (Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence) position: , mismatch: 5, identity: 0.815

tttcaatctcgccaattattctttttt	CRISPR spacer
actgaatctcgccaactattgtttttt	Protospacer
 .* ***********.**** ******

18. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to LR721752 (Aliivibrio wodanis 06/09/160 plasmid 1 complete sequence) position: , mismatch: 5, identity: 0.821

tatcagaaaaagctagagagatactaga	CRISPR spacer
taacagaaaaagcaagagagataattaa	Protospacer
** ********** ********* * .*

19. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP044981 (Bacillus thuringiensis strain BT62 plasmid pBT62C, complete sequence) position: , mismatch: 5, identity: 0.828

taattttctatctttagatttattatatt	CRISPR spacer
tgattttctatctttagctttaatagctt	Protospacer
*.*************** **** **  **

20. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP020751 (Bacillus mycoides strain Gnyt1 plasmid unnamed8, complete sequence) position: , mismatch: 5, identity: 0.828

taattttctatctttagatttattatatt	CRISPR spacer
tgattttctatctttagctttaatagctt	Protospacer
*.*************** **** **  **

21. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP023822 (Escherichia coli strain 7/2 plasmid p7_2.2, complete sequence) position: , mismatch: 5, identity: 0.828

taattttctatctttagatttat-tatatt	CRISPR spacer
taatttggtatctttagatttatacatac-	Protospacer
******  *************** .***.

22. spacer 2.16|1536080|26|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to AP014249 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S36-C17, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 5, identity: 0.808

ataataaaaaactcaccatcacgcag	CRISPR spacer
acaataaaaaactccccatcacggca	Protospacer
*.************ ********  .

23. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to CP046512 (Bacillus cereus strain JHU plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.821

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tacaataaaaagttaaaacagatacaac	Protospacer
*. ********* ******* ******

24. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023246 (Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.821

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tacaataaaaagttaaaacagatacaac	Protospacer
*. ********* ******* ******

25. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 5, identity: 0.821

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
ttaaagaaaaaggtaaaacacaaacaat	Protospacer
* .** **************** ****

26. spacer 2.21|1536399|29|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to MF448557 (Lactococcus phage 37201, complete genome) position: , mismatch: 5, identity: 0.828

acta-aaaaagaaccagtagccctaaagct	CRISPR spacer
-ctatcaaacgaaacagtagccctaaagcc	Protospacer
 ***  *** *** ***************.

27. spacer 2.21|1536399|29|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_049401 (Lactococcus phage 38503, complete genome) position: , mismatch: 5, identity: 0.828

acta-aaaaagaaccagtagccctaaagct	CRISPR spacer
-ctattaaacgaaacagtagccctaaagcc	Protospacer
 ***  *** *** ***************.

28. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to AP013581 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C23-MedDCM-OCT-S23-C56, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.793

taattttctatctttagatttattatatt	CRISPR spacer
atattttttatctttagttttattataaa	Protospacer
  *****.********* *********

29. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to MK250029 (Prevotella phage Lak-C1, complete genome) position: , mismatch: 6, identity: 0.793

taatt--ttctatctttagatttattatatt	CRISPR spacer
--atcaaatctattttcagatttattatatt	Protospacer
  **.   *****.**.**************

30. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to MK250016 (Prevotella phage Lak-A1, complete genome) position: , mismatch: 6, identity: 0.793

taatt--ttctatctttagatttattatatt	CRISPR spacer
--atcaaatctattttcagatttattatatt	Protospacer
  **.   *****.**.**************

31. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to MK250019 (Prevotella phage Lak-A2, complete genome) position: , mismatch: 6, identity: 0.793

taatt--ttctatctttagatttattatatt	CRISPR spacer
--atcaaatctattttcagatttattatatt	Protospacer
  **.   *****.**.**************

32. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_AP017296 (Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence) position: , mismatch: 6, identity: 0.793

taattttctatctttagatttattatatt	CRISPR spacer
aaattttctatctttagttatattagaac	Protospacer
 **************** * ***** * .

33. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NC_006869 (Bacillus mycoides pSin9.7 plasmid) position: , mismatch: 6, identity: 0.793

taattttctatctttagatttattatatt	CRISPR spacer
tgattttctatctttagctttaatagctg	Protospacer
*.*************** **** **  *

34. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 6, identity: 0.793

taattttctatctttagatttattatatt	CRISPR spacer
aaaggttttatctttagattttttatata	Protospacer
 **  **.************* ******

35. spacer 2.17|1536142|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017078 (Novosphingobium resinovorum strain SA1 plasmid pSA3, complete sequence) position: , mismatch: 6, identity: 0.786

acctcaaaaacgatatttcagctacatc	CRISPR spacer
gctccaacaacgatatgtcagctacatt	Protospacer
.*..*** ******** **********.

36. spacer 2.17|1536142|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to MK448732 (Streptococcus phage Javan331, complete genome) position: , mismatch: 6, identity: 0.786

acctcaaaaacgatatttcagctacatc	CRISPR spacer
acctctaaaacgatatttcagaggcaat	Protospacer
***** ***************  .** .

37. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024318 (Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-1) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagaaatacaag	Protospacer
*. .************** * ******.

38. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024207 (Borrelia miyamotoi strain Izh-5 plasmid pIzh5-1) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagaaatacaag	Protospacer
*. .************** * ******.

39. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024335 (Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-1) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagaaatacaag	Protospacer
*. .************** * ******.

40. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024353 (Borrelia miyamotoi strain Izh-16 plasmid pIzh16-1) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagagatacaag	Protospacer
*. .************** * ******.

41. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024325 (Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-6) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagagatacaag	Protospacer
*. .************** * ******.

42. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024392 (Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp70, complete sequence) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagaaatacaag	Protospacer
*. .************** * ******.

43. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024209 (Borrelia miyamotoi strain Izh-5 plasmid pIzh5-2) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagagatacaag	Protospacer
*. .************** * ******.

44. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040828 (Borrelia miyamotoi strain Izh-4 plasmid pIzh4-cp30-2, complete sequence) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagagatacaag	Protospacer
*. .************** * ******.

45. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024373 (Borrelia miyamotoi strain Izh-14 plasmid pIzh14-1) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagaaatacaag	Protospacer
*. .************** * ******.

46. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024381 (Borrelia miyamotoi strain Izh-14 plasmid pIzh14-6) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagagatacaag	Protospacer
*. .************** * ******.

47. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024382 (Borrelia miyamotoi strain Izh-14 plasmid pIzh14-7) position: , mismatch: 6, identity: 0.786

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
tatgataaaaaggtaaaagagatacaag	Protospacer
*. .************** * ******.

48. spacer 2.22|1536464|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

gagcgtaaaaacgttcgcatggctttct	CRISPR spacer
catcggataaacgttcgcatggctttgc	Protospacer
 * ** * ****************** .

49. spacer 2.22|1536464|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 6, identity: 0.786

gagcgtaaaaacgttcgcatggctttct	CRISPR spacer
catcggataaacgttcgcatggctttgc	Protospacer
 * ** * ****************** .

50. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_013393 (Staphylococcus epidermidis plasmid pSK105, complete sequence) position: , mismatch: 6, identity: 0.8

acaataaatttaataatacacatgaaacac	CRISPR spacer
aaaagtcatttaataatacacatgatacat	Protospacer
* **   ****************** ***.

51. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR027875 (Staphylococcus aureus strain BPH2056 isolate BPH2056 plasmid 2) position: , mismatch: 6, identity: 0.8

acaataaatttaataatacacatgaaacac	CRISPR spacer
aaaagtcatttaataatacacatgatacat	Protospacer
* **   ****************** ***.

52. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR027872 (Staphylococcus aureus strain BPH2019 isolate BPH2019 plasmid 3) position: , mismatch: 6, identity: 0.8

acaataaatttaataatacacatgaaacac	CRISPR spacer
aaaagtcatttaataatacacatgatacat	Protospacer
* **   ****************** ***.

53. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_014369 (Staphylococcus aureus plasmid pSK1, complete sequence) position: , mismatch: 6, identity: 0.8

acaataaatttaataatacacatgaaacac	CRISPR spacer
aaaagtcatttaataatacacatgatacat	Protospacer
* **   ****************** ***.

54. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to KX879627 (Campylobacter phage vB_CjeM_Los1, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

55. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to MH107028 (Campylobacter phage CP39, partial genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

56. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_015464 (Campylobacter phage NCTC12673, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

57. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to KF148616 (Campylobacter phage CP8, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

58. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_016562 (Campylobacter phage CPX, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

59. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to KX236333 (Campylobacter phage PC14, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

60. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to JX569801 (Campylobacter phage CP30A, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

61. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to KX229736 (Campylobacter phage PC5, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

62. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_042112 (Campylobacter phage CP81, complete genome) position: , mismatch: 6, identity: 0.8

acaata-aatttaataatacacatgaaacac	CRISPR spacer
-cagcacaatttaataatacacataaaataa	Protospacer
 **..* *****************.***.*

63. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to KM652554 (Streptomyces phage Jay2Jay, complete genome) position: , mismatch: 7, identity: 0.75

tatcagaaaaagctagagagatactaga	CRISPR spacer
ataaagaaaaagctagttagatactagc	Protospacer
    ************  *********

64. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to MF358541 (Streptomyces phage Warpy, complete genome) position: , mismatch: 7, identity: 0.75

tatcagaaaaagctagagagatactaga	CRISPR spacer
ataaagaaaaagctagatagattctagc	Protospacer
    ************* **** ****

65. spacer 2.15|1536015|29|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to KJ489402 (Bacillus phage Riley, complete genome) position: , mismatch: 7, identity: 0.759

aatactactttcatctaaagcaactccgc	CRISPR spacer
taatctagtttcatttaaagcaactcctt	Protospacer
 *  *** ******.************ .

66. spacer 2.15|1536015|29|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to MF765814 (Bacillus phage Taffo16, complete genome) position: , mismatch: 7, identity: 0.759

aatactactttcatctaaagcaactccgc	CRISPR spacer
taatctagtttcatttaaagcaactcctt	Protospacer
 *  *** ******.************ .

67. spacer 2.15|1536015|29|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_022088 (Bacillus phage Troll, complete genome) position: , mismatch: 7, identity: 0.759

aatactactttcatctaaagcaactccgc	CRISPR spacer
taatctagtttcatttaaagcaactcctt	Protospacer
 *  *** ******.************ .

68. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_010010 (Bacillus megaterium QM B1551 plasmid pBM300, complete sequence) position: , mismatch: 7, identity: 0.75

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
gaacataaaaagataaaacaaatacaag	Protospacer
 .. ********.******* ******.

69. spacer 2.18|1536206|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028889 (Borrelia turcica IST7 plasmid lp35, complete sequence) position: , mismatch: 7, identity: 0.75

tggaataaaaaggtaaaacacatacaaa	CRISPR spacer
aaatttaaaatggtaatacacatacaaa	Protospacer
 ..  ***** ***** ***********

70. spacer 2.20|1536335|28|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_017543 (Paenibacillus polymyxa M1 plasmid pPPM1a, complete sequence) position: , mismatch: 7, identity: 0.75

tgacaatggtcgtccaatggctaacaag	CRISPR spacer
cccatatggtcgaccaatggctaaccag	Protospacer
.    ******* ************ **

71. spacer 2.25|1536657|27|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_011973 (Bacillus cereus Q1 plasmid pBc239, complete sequence) position: , mismatch: 7, identity: 0.741

cccacaagatgaagaatcacaacaata	CRISPR spacer
ttcacaagatgaagaatcaaaacgtgt	Protospacer
..***************** ***.

72. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 7, identity: 0.767

acaataaatttaataatacacatgaaacac	CRISPR spacer
atggtaaatttcataatactcatgaaacga	Protospacer
*...******* ******* ********.

73. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026601 (Clostridiaceae bacterium 14S0207 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

acaataaatttaataatacacatgaaacac	CRISPR spacer
atagtaaatttaataatatacttgaaaata	Protospacer
*.*.**************.** *****

74. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043848 (Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

acaataaatttaataatacacatgaaacac	CRISPR spacer
aaaaatcttttaataatacacatgatacat	Protospacer
* **    ***************** ***.

75. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to KX961629 (Bacillus phage BJ4, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

76. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to MN038176 (Bacillus phage Phireball, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

77. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to KU160494 (Vibrio phage vB_VmeM-32, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
attcagaaaaagctagagaaataaagac	Protospacer
  *****************.***  ..

78. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to MF288920 (Bacillus phage Zainny, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

79. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to KU737344 (Bacillus phage Nigalana, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

80. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to KJ489399 (Bacillus phage Hakuna, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

81. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to NC_031027 (Bacillus phage SageFayge, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

82. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to KX349902 (Bacillus phage Kida, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

83. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to NC_031024 (Bacillus phage Belinda, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

84. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to MF288917 (Bacillus phage PPIsBest, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

85. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to MN038179 (Bacillus phage ALPS, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

86. spacer 2.7|1535498|28|NZ_CP016635|CRISPRCasFinder,CRT matches to KU737351 (Bacillus phage NotTheCreek, complete genome) position: , mismatch: 8, identity: 0.714

tatcagaaaaagctagagagatactaga	CRISPR spacer
accttagaaaagctagagagattctaga	Protospacer
  .. ..*************** *****

87. spacer 2.9|1535627|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP020504 (Serratia marcescens strain 95 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.724

gataaaatgacaaaagaagcagcgataac	CRISPR spacer
gacaaaatggcaaaagaagcagcacagga	Protospacer
**.******.*************.  ..

88. spacer 2.9|1535627|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP026402 (Escherichia coli strain ECONIH4 plasmid pECO-e618, complete sequence) position: , mismatch: 8, identity: 0.724

gataaaatgacaaaagaagcagcgataac	CRISPR spacer
gacaaaatggcaaaagaagcagcacagga	Protospacer
**.******.*************.  ..

89. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 8, identity: 0.724

taattttctatctttagatttattatatt	CRISPR spacer
agcttttgtatctttagatttattaagcc	Protospacer
 . **** ***************** ...

90. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NC_010933 (Bacillus cereus strain G9241 plasmid pBC210, complete sequence) position: , mismatch: 8, identity: 0.724

taattttctatctttagatttattatatt	CRISPR spacer
attatttatatctttatatttattatacc	Protospacer
    *** ******** **********..

91. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP009591 (Bacillus cereus G9241 plasmid pBC210, complete sequence) position: , mismatch: 8, identity: 0.724

taattttctatctttagatttattatatt	CRISPR spacer
attatttatatctttatatttattatacc	Protospacer
    *** ******** **********..

92. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to MH552532 (Siphoviridae sp. isolate ctbf3, complete genome) position: , mismatch: 8, identity: 0.724

taattttctatctttagatttattatatt	CRISPR spacer
actattactatttttagatttattatacc	Protospacer
    ** ****.***************..

93. spacer 2.10|1535692|29|NZ_CP016635|CRISPRCasFinder,CRT matches to NZ_CP009940 (Bacillus cereus strain 03BB87 plasmid pBCX01, complete sequence) position: , mismatch: 8, identity: 0.724

taattttctatctttagatttattatatt	CRISPR spacer
attatttatatctttatatttattatacc	Protospacer
    *** ******** **********..

94. spacer 2.14|1535950|29|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to AP013559 (Uncultured Mediterranean phage uvMED isolate uvMED-CGR-C43-MedDCM-OCT-S32-C95, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 8, identity: 0.724

gttgttccattttggaacacatagtcaat	CRISPR spacer
agaaccacattttggaacagatagtcaat	Protospacer
.  ... ************ *********

95. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_012219 (Clostridium botulinum plasmid pC2C203U28 DNA, complete sequence, serotype: type C, strain: (C)-203U28) position: , mismatch: 8, identity: 0.733

acaataaatttaataatacacatgaaacac	CRISPR spacer
ttcataaatttaataatatacataaaaata	Protospacer
 . ***************.****.***

96. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029459 (Clostridium novyi strain 150557 plasmid pCN1, complete sequence) position: , mismatch: 8, identity: 0.733

acaataaatttaataatacacatgaaacac	CRISPR spacer
ttcataaatttaataatatacataaaaata	Protospacer
 . ***************.****.***

97. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029459 (Clostridium novyi strain 150557 plasmid pCN1, complete sequence) position: , mismatch: 8, identity: 0.733

acaataaatttaataatacacatgaaacac	CRISPR spacer
ttcataaatttaataatatacataaaaata	Protospacer
 . ***************.****.***

98. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KR611317 (Rickettsia endosymbiont of Ixodes pacificus strain Humboldt plasmid pREIP, complete sequence) position: , mismatch: 8, identity: 0.733

acaataaatttaataatacacatgaaacac	CRISPR spacer
aagatatatttaataatacacaggaatttt	Protospacer
* .*** *************** *** . .

99. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to MT774398 (CrAssphage cr60_1, complete genome) position: , mismatch: 8, identity: 0.733

acaataaatttaataatacacatgaaacac	CRISPR spacer
agaataaacttaatattacacatgagttct	Protospacer
* ******.****** *********. . .

100. spacer 2.26|1536720|30|NZ_CP016635|CRISPRCasFinder,CRT,PILER-CR matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 9, identity: 0.7

acaataaatttaataatacacatgaaacac	CRISPR spacer
caattaaatttaaaaatacacatgatttca	Protospacer
  * ********* ***********  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

87576 : 97032

Staphylococcus_phage(42.86%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003032762.1\|87576_89361_+	elongation factor 4	A0A2K9L6L3	Tupanvirus	4.2e-23	42.6
WP_081353663.1\|89308_90454_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_081353665.1\|90471_91464_-	hypothetical protein	NA	NA	NA	NA
WP_081353667.1\|91547_92072_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	1.2e-15	37.5
WP_003038172.1\|92068_92512_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.9e-26	45.7
WP_003040999.1\|92521_93733_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.2e-87	44.6
WP_003041003.1\|93725_94331_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-27	35.1
WP_071303909.1\|94323_95391_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.2e-51	35.4
WP_011733569.1\|95781_97032_+	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.6e-29	34.3

DBSCAN-SWA_2

399066 : 408597

Enterococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003038445.1\|399066_399915_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.4e-29	38.4
WP_071304049.1\|400007_400298_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_071304050.1\|400516_401560_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SQF5	Cyanophage	1.2e-54	36.3
WP_071304051.1\|401559_403872_+	phosphoribosylamine--glycine ligase	A0A0M4JBD3	Mollivirus	1.2e-25	30.4
WP_003017844.1\|403875_404451_+	phosphoribosylglycinamide formyltransferase	Q58MV3	Prochlorococcus_phage	2.2e-18	34.7
WP_071304052.1\|404567_405059_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.3e-19	39.5
WP_071304053.1\|405061_406159_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_003026519.1\|406155_406509_-	YraN family protein	NA	NA	NA	NA
WP_071304054.1\|406590_408597_-	M3 family metallopeptidase	A0A1V0SID3	Klosneuvirus	8.2e-52	25.9

DBSCAN-SWA_3

1035593 : 1043911

Alteromonas_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071304357.1\|1035593_1037366_+	ribonucleoside-diphosphate reductase subunit alpha	R4W390	Alteromonas_phage	1.5e-182	57.2
WP_003018894.1\|1037369_1037630_+	glutaredoxin	A0A2L0UZP1	Agrobacterium_phage	6.9e-12	42.7
WP_003033975.1\|1037636_1038869_+	ribonucleotide-diphosphate reductase subunit beta	Q678G9	Lymphocystis_disease_virus	6.9e-102	53.6
WP_071304358.1\|1038865_1040758_-	ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	7.0e-69	33.4
WP_003036633.1\|1040868_1041471_+	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_071304359.1\|1041467_1042520_+	DNA polymerase IV	F1C5A5	Cronobacter_phage	2.2e-08	22.0
WP_014549839.1\|1042859_1043444_-	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_014549840.1\|1043701_1043911_-	hypothetical protein	Q9JMN3	Wolbachia_phage	6.6e-05	45.8

DBSCAN-SWA_4

1051834 : 1110319

Tupanvirus(16.67%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071304857.1\|1051834_1053025_-\|tRNA	tyrosine--tRNA ligase	A0A2I2L594	Orpheovirus	7.3e-08	25.6
WP_003036654.1\|1053138_1054041_+	lipoate--protein ligase	NA	NA	NA	NA
WP_003034000.1\|1054043_1054793_-	hypothetical protein	NA	NA	NA	NA
WP_003015772.1\|1054984_1055536_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_071304364.1\|1055543_1056911_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A2H5BJT2	Erwinia_phage	2.7e-46	29.5
WP_003034008.1\|1059793_1061209_+	Si-specific NAD(P)(+) transhydrogenase	NA	NA	NA	NA
WP_071304365.1\|1061212_1062061_+	prepilin peptidase	NA	NA	NA	NA
WP_071304366.1\|1062070_1062916_+	DsbC family protein	NA	NA	NA	NA
WP_081353748.1\|1062924_1063809_+	class A beta-lactamase	A0A1B0VBP7	Salmonella_phage	1.6e-39	35.6
WP_003026214.1\|1063801_1064377_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_003034020.1\|1064395_1065487_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_003036665.1\|1065501_1065780_+	hypothetical protein	NA	NA	NA	NA
WP_003034027.1\|1065816_1067076_-	DUF21 domain-containing protein	NA	NA	NA	NA
WP_003018840.1\|1067171_1067462_-	50S ribosomal protein L25	NA	NA	NA	NA
WP_003015739.1\|1067561_1068530_-	ribose-phosphate pyrophosphokinase	A0A2K9L8D8	Tupanvirus	9.1e-41	35.3
WP_071304367.1\|1068740_1069748_+	succinylglutamate desuccinylase/aspartoacylase family protein	NA	NA	NA	NA
WP_071304368.1\|1069740_1071024_+	MFS transporter	NA	NA	NA	NA
WP_071304369.1\|1071030_1072317_-	MFS transporter	NA	NA	NA	NA
WP_071304370.1\|1072451_1073195_-\|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	5.2e-12	35.0
WP_003036674.1\|1073490_1074324_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_003034041.1\|1074301_1075477_-	cation:proton antiporter	NA	NA	NA	NA
WP_071304371.1\|1075574_1076207_-	nicotinamide mononucleotide transporter	A0A2I7SAC7	Vibrio_phage	1.5e-07	23.3
WP_071304372.1\|1076206_1076710_-	isochorismatase family protein	NA	NA	NA	NA
WP_071304373.1\|1076815_1077319_-	isochorismatase family protein	NA	NA	NA	NA
WP_003018833.1\|1077446_1078028_+	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_071304374.1\|1078118_1078817_+	aldolase	NA	NA	NA	NA
WP_071304375.1\|1078832_1079969_+	histidine decarboxylase	NA	NA	NA	NA
WP_003034054.1\|1079955_1080768_-	amidohydrolase family protein	NA	NA	NA	NA
WP_003034056.1\|1080932_1081394_+	hypothetical protein	M4QRU0	Micromonas_pusilla_virus	2.6e-22	39.9
WP_003015717.1\|1081429_1081726_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_071304376.1\|1081747_1082335_-	hypothetical protein	NA	NA	NA	NA
WP_071304377.1\|1082383_1083799_-	DNA recombination protein RmuC	NA	NA	NA	NA
WP_081353750.1\|1083824_1084478_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_003034066.1\|1084487_1085681_-	MFS transporter	NA	NA	NA	NA
WP_071304379.1\|1085762_1086278_-	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
WP_003034072.1\|1086374_1087121_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_003036696.1\|1087136_1087796_-	isoprenoid biosynthesis glyoxalase ElbB	NA	NA	NA	NA
WP_003018819.1\|1087825_1088809_-	lipoyl synthase	NA	NA	NA	NA
WP_071304007.1\|1089005_1089998_+\|transposase	IS5 family transposase	E5E3P6	Burkholderia_phage	9.1e-12	24.0
WP_003034079.1\|1090229_1090730_+	ferritin	NA	NA	NA	NA
WP_071304380.1\|1090732_1092205_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	5.9e-23	23.3
WP_071304381.1\|1092376_1093021_+	glutaredoxin 2	NA	NA	NA	NA
WP_003036701.1\|1093022_1093652_+	RnfABCDGE type electron transport complex subunit B	NA	NA	NA	NA
WP_003036703.1\|1093644_1094283_+	endonuclease III	NA	NA	NA	NA
WP_003039521.1\|1094279_1094711_+	DUF1841 family protein	NA	NA	NA	NA
WP_003034090.1\|1094710_1095970_+	hypothetical protein	NA	NA	NA	NA
WP_071304382.1\|1096085_1096772_+	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	3.6e-31	42.9
WP_071304383.1\|1096816_1100242_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_071304384.1\|1100364_1101408_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_003015556.1\|1101435_1101753_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_003034103.1\|1101757_1103455_-	biosynthetic-type acetolactate synthase large subunit	E4WLQ6	Ostreococcus_tauri_virus	1.3e-58	30.2
WP_071304385.1\|1103601_1105284_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_003034109.1\|1105308_1107105_-	threonine synthase	NA	NA	NA	NA
WP_003015672.1\|1107247_1107841_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_014549880.1\|1107837_1108323_-	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_003018795.1\|1108323_1109250_-\|protease	protease modulator HflC	A0A2K9KZA2	Tupanvirus	7.5e-08	21.9
WP_071304386.1\|1109251_1110319_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA

DBSCAN-SWA_5

1220582 : 1229511

Salmonella_phage(28.57%)

integrase

attL 1226812:1226826|attR 1232636:1232650

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071304477.1\|1220582_1221272_+	hypothetical protein	K7ZRM9	Xanthomonas_citri_phage	1.2e-15	29.6
WP_071304478.1\|1221243_1222125_+	recombinase RecT	A0A2H5BFV3	Vibrio_phage	3.0e-43	45.4
WP_071304479.1\|1222140_1222563_+	hypothetical protein	T1S9H7	Salmonella_phage	9.5e-19	44.9
WP_071304480.1\|1222555_1222846_+	hypothetical protein	NA	NA	NA	NA
WP_071304481.1\|1222848_1223073_+	hypothetical protein	NA	NA	NA	NA
WP_071304482.1\|1223156_1223384_+	hypothetical protein	NA	NA	NA	NA
WP_071304483.1\|1223380_1223659_+	hypothetical protein	NA	NA	NA	NA
WP_071304484.1\|1223642_1223831_+	hypothetical protein	NA	NA	NA	NA
WP_071304485.1\|1223892_1224747_+	hypothetical protein	A0A0M4S6X1	Salmonella_phage	1.2e-41	36.3
WP_081353763.1\|1224907_1225855_+	hypothetical protein	W8CYS3	Bacillus_phage	3.9e-20	31.7
WP_071304487.1\|1225861_1226293_-	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_071304488.1\|1226292_1226544_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_071304489.1\|1226527_1226761_-	DUF4160 domain-containing protein	NA	NA	NA	NA
1226812:1226826	attL	NA	NA	NA	NA
WP_071304490.1\|1226894_1228088_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	6.8e-54	33.5
WP_071304491.1\|1228344_1229511_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	5.8e-66	38.2
1232636:1232650	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP016635

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection