CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017961	Pasteurella multocida strain Razi_Pm0001, complete genome	3 crisprs	cas1,cas9,csa3,cas3,DEDDh,cas8f,cas5f,cas7f,cas6f,cas3-cas2,DinG	1	18	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017961_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017961_1

192840-193403

orTypeII

Consensus_repeat	Method
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	CRISPRCasFinder
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	CRT
AGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	PILER-CR

8 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_CP017961_1

>merge|NZ_CP017961|1|192840-193403|CRISPRCasFinder,CRT,PILER-CR
GTTATTTTTGTGGCTCTCATTTCGCAGTGCTACAATATACATGCTAATCAATTTGATAAGGCTGGAGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAATGGTAGATAAAAGTTAAATTCATTGAGTTTAGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAATTTTGCTTTCTTCGCAAATAACGCTTTGACTGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAATACCAAGAGTTAACTTATAGATGACCAAGAGGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAATTCAAGTTGCCAATTACAGGGACCAAAACGGGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAATAGGTACGGTCTCCTGCTGGTACATATCGAGGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAATAATGGCTGTAGTACTTTATACCACCTCAGCGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAATAGGAAGGTAGGCACTTCGATGACCTCAGAGGTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT

>NZ_CP017961|1|1|192840-193403|CRISPRCasFinder
GTTATTTTTGTGGCTCTCATTTCGCAGTGCTACAAT	ATACATGCTAATCAATTTGATAAGGCTGGA
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	GGTAGATAAAAGTTAAATTCATTGAGTTTA
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	TTTGCTTTCTTCGCAAATAACGCTTTGACT
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	ACCAAGAGTTAACTTATAGATGACCAAGAG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	TCAAGTTGCCAATTACAGGGACCAAAACGG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	AGGTACGGTCTCCTGCTGGTACATATCGAG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	AATGGCTGTAGTACTTTATACCACCTCAGC
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	AGGAAGGTAGGCACTTCGATGACCTCAGAG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT

>NZ_CP017961|1|1|192840-193403|CRT
GTTATTTTTGTGGCTCTCATTTCGCAGTGCTACAAT	ATACATGCTAATCAATTTGATAAGGCTGGA
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	GGTAGATAAAAGTTAAATTCATTGAGTTTA
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	TTTGCTTTCTTCGCAAATAACGCTTTGACT
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	ACCAAGAGTTAACTTATAGATGACCAAGAG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	TCAAGTTGCCAATTACAGGGACCAAAACGG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	AGGTACGGTCTCCTGCTGGTACATATCGAG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	AATGGCTGTAGTACTTTATACCACCTCAGC
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT	AGGAAGGTAGGCACTTCGATGACCTCAGAG
GTTGTAGTTCCCTCTCTCATTTCGCAGTGCTACAAT

>NZ_CP017961|1|1|192853-193403|PILER-CR
CTCTCATTTCGCAGTGCTACAATATACATGCTAATCA	ATTTGATAAGGCTGGAGTTGTAGTTCCCT
CTCTCATTTCGCAGTGCTACAATGGTAGATAAAAGTT	AAATTCATTGAGTTTAGTTGTAGTTCCCT
CTCTCATTTCGCAGTGCTACAATTTTGCTTTCTTCGC	AAATAACGCTTTGACTGTTGTAGTTCCCTC
TCTCATTTCGCAGTGCTACAATACCAAGAGTTAACTT	ATAGATGACCAAGAGGTTGTAGTTCCCTC
TCTCATTTCGCAGTGCTACAATTCAAGTTGCCAATTA	CAGGGACCAAAACGGGTTGTAGTTCCCTC
TCTCATTTCGCAGTGCTACAATAGGTACGGTCTCCTG	CTGGTACATATCGAGGTTGTAGTTCCCTC
TCTCATTTCGCAGTGCTACAATAATGGCTGTAGTACT	TTATACCACCTCAGCGTTGTAGTTCCCTC
TCTCATTTCGCAGTGCTACAATAGGAAGGTAGGCACT	TCGATGACCTCAGAGGTTGTAGTTCCCTC
TCTCATTTCGCAGTGCTACAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017961.1\|WP_005751838.1\|194925_198096_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP017961.1\|WP_016534312.1\|182703_184848_-\|polyribonucleotide-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|236995
NZ_CP017961.1\|WP_005757242.1\|185296_186739_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NZ_CP017961.1\|WP_005733757.1\|193636_193963_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP017961.1\|WP_005723343.1\|198618_198900_-\|alternative-ribosome-rescue-factor-A	unknown	unknown	gnl\|CDD\|225578
NZ_CP017961.1\|WP_005751839.1\|198320_198614_-\|DUF5377-domain-containing-protein	unknown	unknown	gnl\|CDD\|375144
NZ_CP017961.1\|WP_005733743.1\|187492_188281_+\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|226297
NZ_CP017961.1\|WP_005751837.1\|193955_194870_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP017961.1\|WP_005717494.1\|198972_199323_-\|arsenate-reductase-(glutaredoxin)	unknown	unknown	gnl\|CDD\|272855
NZ_CP017961.1\|WP_005751833.1\|189622_190630_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NZ_CP017961.1\|WP_071543602.1\|179783_181616_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|236941
NZ_CP017961.1\|WP_005751835.1\|191419_192793_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179883
NZ_CP017961.1\|WP_005751844.1\|204103_205315_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP017961.1\|WP_005723318.1\|181723_182620_-\|lipoprotein-NlpI	unknown	unknown	gnl\|CDD\|227124
NZ_CP017961.1\|WP_005751828.1\|178835_179684_+\|ModD-protein	unknown	unknown	gnl\|CDD\|180397
NZ_CP017961.1\|WP_005751832.1\|188366_189515_-\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|235346
NZ_CP017961.1\|WP_005751840.1\|199402_200467_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP017961.1\|WP_005751834.1\|190630_191404_+\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|239782
NZ_CP017961.1\|WP_005751843.1\|203632_204076_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NZ_CP017961.1\|WP_017350283.1\|200524_203623_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911

Protein	Function_ID	Function_description	E-value
NZ_CP017961.1\|WP_005751838.1\|194925_198096_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP017961.1\|WP_016534312.1\|182703_184848_-\|polyribonucleotide-nucleotidyltransferase	gnl\|CDD\|236995	PRK11824, PRK11824, polynucleotide phosphorylase/polyadenylase; Provisional.	0
NZ_CP017961.1\|WP_005757242.1\|185296_186739_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP017961.1\|WP_005733757.1\|193636_193963_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	3.88257e-59
NZ_CP017961.1\|WP_005723343.1\|198618_198900_-\|alternative-ribosome-rescue-factor-A	gnl\|CDD\|225578	COG3036, COG3036, Uncharacterized protein conserved in bacteria [Function unknown].	1.95702e-25
NZ_CP017961.1\|WP_005751839.1\|198320_198614_-\|DUF5377-domain-containing-protein	gnl\|CDD\|375144	pfam17347, DUF5377, Family of unknown function (DUF5377). This is a family of unknown function found in Pasteurellaceae.	5.24439e-64
NZ_CP017961.1\|WP_005733743.1\|187492_188281_+\|glycosyl-transferase	gnl\|CDD\|226297	COG3774, OCH1, Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane].	6.4748e-84
NZ_CP017961.1\|WP_005751837.1\|193955_194870_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.63965e-145
NZ_CP017961.1\|WP_005717494.1\|198972_199323_-\|arsenate-reductase-(glutaredoxin)	gnl\|CDD\|272855	TIGR00014, Putative_arsenate_reductase., arsenate reductase (glutaredoxin). This model describes a distinct clade, including ArsC itself, of the broader ArsC family described by Pfam pfam03960. This clade is almost completely restricted to the Proteobacteria. An anion-translocating ATPase has been identified as the product of the arsenical resistance operon of resistance plasmid R773. When expressed in Escherichia coli this ATP-driven oxyanion pump catalyses extrusion of the oxyanions arsenite, antimonite and arsenate. The pump is composed of two polypeptides, the products of the arsA and arsB genes. The pump alone produces resistance to arsenite and antimonite. This protein, ArsC, catalyzes the reduction of arsenate to arsenite, and thus extends resistance to include arsenate. [Cellular processes, Detoxification].	1.56527e-62
NZ_CP017961.1\|WP_005751833.1\|189622_190630_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	2.19032e-176
NZ_CP017961.1\|WP_071543602.1\|179783_181616_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|236941	PRK11634, PRK11634, ATP-dependent RNA helicase DeaD; Provisional.	0
NZ_CP017961.1\|WP_005751835.1\|191419_192793_+\|argininosuccinate-lyase	gnl\|CDD\|179883	PRK04833, PRK04833, argininosuccinate lyase; Provisional.	0
NZ_CP017961.1\|WP_005751844.1\|204103_205315_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.71127e-64
NZ_CP017961.1\|WP_005723318.1\|181723_182620_-\|lipoprotein-NlpI	gnl\|CDD\|227124	COG4785, NlpI, Lipoprotein NlpI, contains TPR repeats [General function prediction only].	6.04811e-159
NZ_CP017961.1\|WP_005751828.1\|178835_179684_+\|ModD-protein	gnl\|CDD\|180397	PRK06096, PRK06096, molybdenum transport protein ModD; Provisional.	0
NZ_CP017961.1\|WP_005751832.1\|188366_189515_-\|acetylornithine-deacetylase	gnl\|CDD\|235346	PRK05111, PRK05111, acetylornithine deacetylase; Provisional.	0
NZ_CP017961.1\|WP_005751840.1\|199402_200467_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.42367e-56
NZ_CP017961.1\|WP_005751834.1\|190630_191404_+\|acetylglutamate-kinase	gnl\|CDD\|239782	cd04249, AAK_NAGK-NC, AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of ornithine biosynthesis. There are two variants of this pathway. In one, typified by the pathway in Escherichia coli, glutamate is acetylated by acetyl-CoA and acetylornithine is deacylated hydrolytically. In this pathway, feedback inhibition by arginine occurs at the initial acetylation of glutamate and not at the phosphorylation of NAG by NAGK. Homodimeric NAGK-NC are members of the Amino Acid Kinase Superfamily (AAK).	2.26873e-133
NZ_CP017961.1\|WP_005751843.1\|203632_204076_-\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	5.01837e-82
NZ_CP017961.1\|WP_017350283.1\|200524_203623_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0

>NZ_CP017961.1|WP_005751835.1|191419_192793_+|argininosuccinate-lyase
MALWGGRFTQAADKRFKDFNDSLRFDYRLAEQDIEGSIGWSKALVSVGVLTVQEQQQLESALNTLLIEVRSNPQAILQDDAEDIHSWVESKLIDKVGNLGKKLHTGRSRNDQVALDIKMWCKQRVIELQSSLHALQCKLVETAENNQHAVMPGYTHLQRAQPITFAHWCMAYVEMLDRDYSRLTDAYQRMNSCPLGSGALAGTAYAIDREQLALDLGFDVATRNSLDSVSDRDHIVELLSTASLSMAHLSRFAEDMIIFNSGESNFVELSDRVTSGSSLMPQKKNPDACELIRGKAGRVMGALTGMLMTLKGLPLAYNKDMQEDKEGIFDALDTWQDCIDMAALVLDGIQVNVERTKEAALKGYSNATELADYLVAKGVPFRDSHHIVGETVVYAIQQHKALEALSVAEFKQFSDVVEEDVYQILSLQSCLDKRCAKGGVSPLRVAEAIAEAKARLS
>NZ_CP017961.1|WP_005751834.1|190630_191404_+|acetylglutamate-kinase
MKPLVIKLGGALLDTPAAMENLFTALANYQQNFDRPLVIVHGGGCIVDELMQRLHLPVQKKNGLRVTPSDHIEIITGALAGIANKTLVAQAAKFHLNPVGLCLADGNLTYATQLDPELGHVATVVPKNPALLNNLLGEAFLPIISSIAVDKQGLLMNVNADQAATAIAALIQADLIMLSDVDGVLDANKQRLPELNGAQIEQLIKDNVITDGMVVKVNAALDAAKMLNQGVDIANWKYPEKLTALFAGEIIGTRIKP
>NZ_CP017961.1|WP_005751833.1|189622_190630_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MQKAIIIGASGYTGAELARILIKHPKFELTGLYVSRQSQDANKCISDIYPQLKCVVDLPLQPLPEQLTQLAQQADLVFLATAHEVSHDLAPVFLQHQCKVFDLSGAFRVNNAAFYRTFYGFEHQHPELLTQAVYGLAEWNAHQIKQTDLVAVAGCYPTVSQLSLKPLIAHNLLDLTQLPVINAVSGVSGAGRKATLTSSFCEVSLNAYGVFNHRHQPEIATHLGTEVIFTPHLGNFKRGILATITAKLKTGVSDEQIRVAYQQAYANKPLVRVYEQGLPSIKAVEFTPYCDIGFATQNGHIIIIGAEDNLLKGAAAQAVQCANIRYGLTETLGLL
>NZ_CP017961.1|WP_005751832.1|188366_189515_-|acetylornithine-deacetylase
MKKIPSFLQMYSALIASPTMSSIDPHFDQSNRTLIELLANWLSSLGFKTEVIPLEGSRDKFNLLATYGEGEGGLLLAGHTDTVPFDEGRWQFDPFKLTEKDGKFYGLGTADMKGFFAFVIDAVSQLDLTRLTKPLRILATADEETTMLGARTFIQHSHIRPDCAIIGEPTSLKPIRAHKGHVGEALRITGKSGHSSDPSKGINAIELMHEATGYLMQMRDELRQKYHHSAFNIPYPTMNFGAISGGDAVNRICACCELHFDIRPLPNLRLTDLNEMLQAKLAPMFEKWGDRISLQALHDPIPGYECAHSAQVVQVVEKLLGEQCKTVNYCTEAPFIQQLCPTLVLGPGSIEQAHQPDEFLSAEFIDPTRELLIKLIGQFCTG
>NZ_CP017961.1|WP_005733743.1|187492_188281_+|glycosyl-transferase
MYKPVKNKHLILITNGMTRLLGNIVKTLSYPFHALLPKMRFTIPEFSPAKRQSHKKTKINRVIWQTNYSNKVTLPVYCNYLFNRLLSLSYDYRYVSTEARADYIKTHADERTFNAYSKLTDGAAQADFWRIFTLYHEGGIYMDIDGHLVWCLDSIIDEEDSEVVISRRGRYTNFFLASAKGNPFLKDTLEIIISNIEQKRIEGGVFCLTGPETLIKALENKEVNSRLDKLTCSQGTFTNEYFQYIDKKRGKWIHAKNEDLLK
>NZ_CP017961.1|WP_005757242.1|185296_186739_-|glutamate--tRNA-ligase
MKAEALFDLDPGVKVRTRFAPSPTGYLHVGGARTALYSWLYAKHHQGEFVLRIEDTDLERSTPEATAAILEGMAWLNLAWEHGPYFQTKRFDRYNQVIDQMIEQGLAYRCYCSKERLEDLRNTQEQNKQKPRYDRHCLGDHKHSPEQPHVVRFKNPTEGSVVFEDAVRGRIEISNAELDDLIIRRTDGSPTYNFCVVVDDWDMGITHVVRGEDHINNTPRQINILKALGAPIPTYAHVSMILGDDGQKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWGHGDQEIFSVEEMIKLFELESVSKSASAFNTEKLLWLNHHYIRELPAEYVAKHLAWHYQDQGIDTSNGPALEDIVKMLAERCKTLKEMAAASRYFFEDFDSFDEAAVKKHFKAAAIEPLEKIKEKLTALESWDLHSTHQAIEQTAAELELGMGKVGMPLRVAVTGSGQSPSMDVTLVGIGKARTLVRIQKAIDFIKSQNV
>NZ_CP017961.1|WP_016534312.1|182703_184848_-|polyribonucleotide-nucleotidyltransferase
MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKDVKEGQDFFPLTVNYQERTYAAGRIPGGFFKREGRPSEGETLIARLIDRPIRPLFPEGFYNEIQIVATVVSVNPQICPDLVAMIGASAALSLSGVPFNGPIGAARVGFIDDQFVLNPTMNEQKQSRLDLVVAGTDKAVLMVESEADVLTEEQMLAAVVFGHQQQQVVIDAIKEFTAEAGKPRWDWVAPEPNTALIEKVKAIAEARLGEAYRITEKQARYEQIDAIKADVIAQITAEVAEGEDISEGKIVDIFTALESQIVRSRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERSDHFLFHYNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPTFAEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEDEKFVVLSDILGDEDHLGDMDFKVAGTRTGVTALQMDIKIEGITAEIMQIALNQAKSARLHILGVMEQAIPAPRADISDFAPRIYTMKIDPKKIKDVIGKGGATIRALTEETGTSIDIDDDGTVKIAAVDGNSAKEVMARIEDITAEVEAGAVYKGKVTRLADFGAFVSIVGNKEGLVHISQIAEERVEKVSDYLAVGQEVTVKVVEIDRQGRIRLTMKEVAPKQEHVDSVVADVAAEENA
>NZ_CP017961.1|WP_005723318.1|181723_182620_-|lipoprotein-NlpI
MKQFHPWLKCLLIFPFWVCCLTACVNHEQVFLSKEKLMLAEQHPNDHLEHEVMVAQISELLLVKGLKKEERAILHFERGVLYDSLGLWALARYDFDQTLALYPKLAAAFNYLGLYLLLEEDYSASLDIFNVLFELDPQYEYAFLNRGLNFYYVGRYELAQRDFLQFYQADKSDPYRTLWLYLNELKHNPQDASKNLAQRAMGLSDEYWGTYLVQYYLGKLSVKALFAQAQQFAQTNRAKYAEILTETYFYLAKLKLNSGQINEAETLFKLAIANQVYNFVEYRFALFELLKLKQSSKP
>NZ_CP017961.1|WP_071543602.1|179783_181616_-|DEAD/DEAH-box-helicase
MTETTMTFNDLGLPEFLLNAVSDLGFETPSPIQQSCIPNLLNGHDVLGMAQTGSGKTAAFSLPLLAQIDLDKKYPQMLVMAPTRELAIQVADACEHFCKYAKNTNIVTLYGGQRYDIQLRALRQGAQVVVGTPGRILDHIRRGTLDLSNLRFMVLDEADEMLRMGFIDDVETVMAELPEQHQTALFSATMPDPIRRITKRFMKDPKEIKIKSTQTTNPDITQSCWYVHGFRKNDALLRFLEVEKFDAAIIFTRTKTGTLDVTELLEKHGFRAEALNGDMTQQLREQTLDRLRNGSLDILVATDVAARGLDVERISLVVNYDIPLDAESYVHRIGRTGRAGRTGRALLFVEPRERRLLRNIEQLTKKPITEVEVPNHEVLQACRREKFKAKITVQLEHHDLGLYRSLLEDMFTADQDQEDIAAAMLMLLQGKQKLILPADPIIDRKTSRGDRGERRERGGRENPRSAERRGYGTPQAMDLYRIEVGRLDGAEVRHIVGAIANEGDINSRYIGHIKLYDDYTTIELPQGMPKELLGVFAKTRVMNKQMQMSFVGASNAGSSRDRDDFADRRGGKRKGRGDEPRFGREDRKFKEKSQRTFNDRPRRERRERQK
>NZ_CP017961.1|WP_005751828.1|178835_179684_+|ModD-protein
MLYFSDNELDDFLLEDIYRGDLTTHALGLESIPAKICFKRKNAGIVAGISIAEKLLRKLDIHPQVYVKEGEFVEAGSLLLSAKGSANKLHQAWKVVQLVLEWSCGVAQYTAEMISNAKAINPAAVVACTRKSIPNTRKLATNAVLAAGGHIYRQGLSETLLVFTNHRNLLSDPEDWQGIVTRLKQQAPENKITLEADNLVQFEQILTADPDIIQLDKFTLEQVKQALHLLALANKNITLSVAGGVNKHNVAEYAKLGIQLFITSAPYYAAPEDIKVIIEKQV
>NZ_CP017961.1|WP_005733757.1|193636_193963_-|CRISPR-associated-endonuclease-Cas2
MSEGKFMRLIVFFDLPVTTKAKRKAANQFRQFLLKDGYQMLQLSVYARIIRGRDSMQKHNKRLSDHLPEEGSIRCLEVTEKQFAGMKILLGRLRLQEKKVNANQMLLF
>NZ_CP017961.1|WP_005751837.1|193955_194870_-|type-II-CRISPR-associated-endonuclease-Cas1
MSWRSILISQGGKLSLQRKQMLIQQSNNSFTVPLEDIAVIVIESKETLITAPLLSALAQYGVTLLTCDEQFLPCGQWLPFGQYYRQLKTLKLQLETTLPQKKQLWQKIVQQKIRNQGFVLEQVGYFNETKRLNRMANQVKSGDKENVEAQAALIYFQTLFGKTFKRSEENNINAHLNYAYTVLRSAIARALVLYGWLPQLGIFHRSEVNPFNLADDFVEPFRPLVDLMVWQLWHTNQLTSGLSPNTKQKLISLLHHQMSFQEETFSVLAAIDRTVGSFQAALTTPNANLLKLPEILPLKEHQYE
>NZ_CP017961.1|WP_005751838.1|194925_198096_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MQTTNLSYILGLDLGIASVGWAVVEINENEDPIGLIDVGVRIFERAEVPKTGESLALSRRLARSTRRLIRRRARRLLLAKRFLKREGILSTTDLEKGLPNQAWELRVAGLERRLSAIEWGAVLLHLIKHRGYLSKRKNESQTNNKELGALLSGVAQNHQLLQSDDYRTPAELALKKFAKEEGHIRNQRGAYTHTFNRLDLLAELNLLFAQQHQFGNPHCKEHIQQYMTELLMWQKPALSGEAILKMLGKCTHEKNEFKAAKHTYSAERFVWLTKLNNLRILEDGAERALNEEERQLLINHPYEKSKLTYAQVRKLLGLSEQAIFKHLRYSKENAESATFMELKAWHAIRKALENQGLKDTWQDLAKKPDLLDEIGTAFSLYKTDEDIQQYLTNKVPNSVINALLVFLNFDKFIELALKSLRKILPLMEQGKRYDQACREIYGHHYGEANQKTSQLLPAIPAQEIRNPVVLRTLSQARKVINAIIRQYGSPARVHIETGRELGKSFKERREIQKQQEDNRTKRESAVQKFKELFSDFSSEPKSKDILKFRLYEQQHGKCLYSGKEINIHRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLASENQNKGNQTPYEWLQGKINSERWKNFVALVLGSQCSAAKKQRLLTQVIDDNKFIDRNLNDTRYIARFLSNYIQENLLLVGKNKKNVFTPNGQITALLRSRWGLIKIRENNDRHHALDAIVVACATPSMQQKITRFIRFKEVHPYKIENRYEMVDQESGEIISPHFPEPWAYFRQEVNIRVFDNHPDTVLKEMLPDRPQANHQFVQPLFVSRAPTRKMSGQGHMETIKSAKRLAEGISVLRIPLTQLKPNLLENMVNKEREPALYAGLKARLAEFNQDPAKAFTTPFYKQGGQQVKAIRVEQVQKSGVLVRENNGVADNASIVRTDVFIKNNKFFLVPIYTWQVAKGILPNKAIVAHKNEDEWEEMDEGAKFKFSLFPNDLVELKTKKEYFFGYYIGLDRATGNISLKEHDGEISKGKDGVYRVGVKLALSFEKYQVDELGKNRQICRPQQRQPVR
>NZ_CP017961.1|WP_005751839.1|198320_198614_-|DUF5377-domain-containing-protein
MTVQTEVLFSNNWNVRISDPGEEGAHSHFFETIYITLVAHIDGSNISYEFTRKVEEQVKIHRTFTDLSELFKFLGDYLDPVSMGFLGIKIGNLGVKA
>NZ_CP017961.1|WP_005723343.1|198618_198900_-|alternative-ribosome-rescue-factor-A
MAKKQKQPLSAQPYQHSRGVIRDNAICALLHDPLFRQRIEKKRKGKGSYQRKAKHVGKYFEKPDYKIFDLKDFIIGFFLTIFYNNATHLNSAR
>NZ_CP017961.1|WP_005717494.1|198972_199323_-|arsenate-reductase-(glutaredoxin)
MCVTIYHNPRCSKSRETLALLEAKYGQPKIELYLEQQFSASQLQQIAQKLGVTSFREMMRTKDELYRDLGLDKPEVSEQQLLEALVAHSSLLERPIVIHGDKAKIGRPPESVLEIL
>NZ_CP017961.1|WP_005751840.1|199402_200467_+|AI-2E-family-transporter
MIEMLKNWYNNRFSDPQAMGLFAILLFGFISIYFFSHLIAPLLIAIVLAYLLEWPIRVLTEKLKFPRLLSTAIIFGGFLGLILVIVLVFIPTLWTQTLNLVTDLPHMFNKLNEWLLSLPEHYPELVDYQTIDSVLSTVRSKILGFGESALKFSLTSLLSLVTLGIYAFLVPLMVFFLLKDKTELIASVSRFLPRNRTLASSVWKEMQQQIANYIRGKLFEIIIVTAVTYAIFVFFNLNYSLLLAVAVGLSVLVPYIGAVLVTIPIALVAVAQFGITPTFWYIITAYVISQILDGNLLVPFLFSEAVNLHPLTIIIAVLIFGGLWGFWGVFFAIPLATLVKAVVNAWPSTEQDTR
>NZ_CP017961.1|WP_017350283.1|200524_203623_-|efflux-RND-transporter-permease-subunit
MRFTDIFIRRPVLAVSISLLIIILGLQAIAKLAVREYPKMTTTVINVSTVYPGADASLIQAFITSKLEEAVAQADNIDYLSSKSSPNNSLITIKMKLNTEPNGALADVLAKVNSVRSQLPRGIDDPVITSSTGGTGMMYIQFSSTKLDASQVTDYIERVIKPQFFTVEGVAEVQIFGASDYALRIWLDPAKMAAQNLSAMAVRNALSSNNVQTAAGNDNGFYVTYKNKVETTTKSVEELGNLIISSQGDKLVRLRDIAEVELNKSSDSSRAVANGFESVVLAINPTSSANPLVVAENVRPLYEQIKQNLPDSMQVEILYDTTIAINSSIDEVIKTILEATIIVLVVITLFIGSLRAILIPVITIPISLIGVIMLLQAFDFSINLMTLLALILAIGLVVDDAIVVLENVDRHIKLGETPFRAAIIGTREIAVPVISMTIALMAVYSPMALMDGITGSLFKEFALTLAGAVFISGIVALTLSPMMSSKLLKPHTDPSKLEQCIEKMLTTINQGYNYALNLVMASRRCMLAFAAVIFATLPFLFNGLASELTPAEDKGAFMVIGRAPSNVNVDYVQEAMHEYEQILKDTPEVDFSMVISGAMGSNQSFSVVTLKDWKERTRSQAEILAELNKKSAHIPEVALTGFNFPEINTGEQGPPIGFVISTASGYEDLANVAEDFLQEMKKSGHFVYTALDLKFDTAQMRIKVDKEKAGTYGVTMQQISATLGSFLSAATIERVDIDGRAYRIIMQVKRGERLSPESLNNYYVTASNGKSVPLSSFLTMTLESQPTSLPRFSQLNSAVISAVPLPTKSTGEAIAWLKMAAKEYLPQGYNYDFTGEARQLVQEGNALAVTFVLAVVIIFLVLAIQFESIRDPLVIMISVPLAVSGALLMLNFLGFFRIPGTSLNIYSQVGLITLVGLITKHGILMCEVAKEEQLQHGKNRIEAITEAAKVRLRPILMTTAAMIAGLIPLLYASGAGAVSRFSIGIVIVSGLAIGTLFTLFVLPVIYSYIATEHKPLPEFDESIKPLTDNSAH
>NZ_CP017961.1|WP_005751843.1|203632_204076_-|GAF-domain-containing-protein
MNYALLLKQLEQILEPETYIISRMANTSAFLYQHMPELNWVGFYLVKDGVLKVGPFQGKVACSDIGFGKGVCGYTWQTGTTTVVDDVHQFAGHIACDSASQSEVVVPIFQGGEMIAELDVDSPRLARFSAEDVAFLENCAALICIKE
>NZ_CP017961.1|WP_005751844.1|204103_205315_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MSVTQANQPKRSHSIAMKIILGVIVLLFAGVIIFNVIKGKMIEKFIAGAGEKIYPVTAMTIQPQQWTPVIETTGIVRPNQGAMLSAQTSGTVQQVLVQSGQHVKKGEVLVVLDSSVELANLKASQAQLLSVKATYQRYLSLYKTKSVSQQELDNAKSAYEALESNIAALKAGIARRQILAPFDGQTGIVKVNVGQYVNPGMEIVRVEDTSSMKIDFALSQTELEHLHVGQKVTATADARSGETFAAKITAIEPAISATTGLIDVQATFEPEDGRKLLSGMFTRLRVALPTKYDQVVVPQVAINYNMYGEIAYILSELSAEERETLVARQDFDREKIDNAYRVKQVTVFTQDRQGIYAQLKGEEIKPGDKIVTGGQQNLSNGSLVLVADKAGVGTMQPAVKNNL

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Crispr_ID: NZ_CP017961_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017961_2

971683-972311

Unclear

I-F

Consensus_repeat	Method
GTTAACTGCCGTATAGGCAGCTTAGAAA	PILER-CR
GTTAACTGCCGTATAGGCAGCTTAGAAA	CRISPRCasFinder
GTTAACTGCCGTATAGGCAGCTTAGAAA	CRT

10 spacers

cas3

The CRISPR arrays of NZ_CP017961_2

>merge|NZ_CP017961|2|971683-972311|PILER-CR,CRISPRCasFinder,CRT
GTTAACTGCCGTATAGGCAGCTTAGAAACGGCACTGAGTGCGACAATAGAGCCAACTGACGTTAACTGCCGTATAGGCAGCTTAGAAATATTCAAAAAGTTAATCTTTATACTTCTTCAAGTTAACTGCCGTATAGGCAGCTTAGAAAAGAATGTGGCGTTAAGTTAGCAAGACAGCGATGTTAACTGCCGTATAGGCAGCTTAGAAAAGAATGTGGCGTTAAGTTAGCAAGACAGCGATGTTAACTGCCGTATAGGCAGCTTAGAAAAGAATGTGGCGTTAAGTTAGCAAGACAGCGATGTTAACTGCCGTATAGGCAGCTTAGAAAAAAAGTGGAAGAAAGCAAAATCACAGCGACACGTTAACTGCCGTATAGGCAGCTTAGAAATAGCTGTTTTGGTTGAGTTTTTTATCGGCTACGTTAACTGCCGTATAGGCAGCTTAGAAAATAGGGACGCTTGCGGTTTATGGATTTTTTATGTTAACTGCCGTATAGGCAGCTTAGAAAAAGTTGTTATATTAAGCATGAAGAAATGAAACGTTAACTGCCCGTGTAGGCAGCTTAGAAAAGTCTGTTATTGATTTTCTCAAGCGTTATTTCGTTAACTGCCGTATAGGCAGTTTCAATT

>NZ_CP017961|2|2|971683-972010|PILER-CR
GTTAACTGCCGTATAGGCAGCTTAGAAA	CGGCACTGAGTGCGACAATAGAGCCAACTGAC
GTTAACTGCCGTATAGGCAGCTTAGAAA	TATTCAAAAAGTTAATCTTTATACTTCTTCAA
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA

>NZ_CP017961|2|2|971683-972311|CRISPRCasFinder
GTTAACTGCCGTATAGGCAGCTTAGAAA	CGGCACTGAGTGCGACAATAGAGCCAACTGAC
GTTAACTGCCGTATAGGCAGCTTAGAAA	TATTCAAAAAGTTAATCTTTATACTTCTTCAA
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AAAAGTGGAAGAAAGCAAAATCACAGCGACAC
GTTAACTGCCGTATAGGCAGCTTAGAAA	TAGCTGTTTTGGTTGAGTTTTTTATCGGCTAC
GTTAACTGCCGTATAGGCAGCTTAGAAA	ATAGGGACGCTTGCGGTTTATGGATTTTTTAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AAGTTGTTATATTAAGCATGAAGAAATGAAACG
TTAACTGCCCGTGTAGGCAGCTTAGAAA	AGTCTGTTATTGATTTTCTCAAGCGTTATTTC
GTTAACTGCCGTATAGGCAGTTTCAATT

>NZ_CP017961|2|2|971683-972251|CRT
GTTAACTGCCGTATAGGCAGCTTAGAAA	CGGCACTGAGTGCGACAATAGAGCCAACTGAC
GTTAACTGCCGTATAGGCAGCTTAGAAA	TATTCAAAAAGTTAATCTTTATACTTCTTCAA
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AGAATGTGGCGTTAAGTTAGCAAGACAGCGAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AAAAGTGGAAGAAAGCAAAATCACAGCGACAC
GTTAACTGCCGTATAGGCAGCTTAGAAA	TAGCTGTTTTGGTTGAGTTTTTTATCGGCTAC
GTTAACTGCCGTATAGGCAGCTTAGAAA	ATAGGGACGCTTGCGGTTTATGGATTTTTTAT
GTTAACTGCCGTATAGGCAGCTTAGAAA	AAGTTGTTATATTAAGCATGAAGAAATGAAACG
TTAACTGCCCGTGTAGGCAGCTTAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017961.1\|WP_005736824.1\|974439_974847_-\|copper-chaperone-PCu(A)C	unknown	unknown	gnl\|CDD\|225403
NZ_CP017961.1\|WP_005752314.1\|961542_962211_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380324
NZ_CP017961.1\|WP_005752322.1\|969380_970094_-\|tRNA1(Val)-(adenine(37)-N6)-methyltransferase	unknown	unknown	gnl\|CDD\|226608
NZ_CP017961.1\|WP_005752323.1\|970205_971534_+\|ATP-dependent-RNA-helicase-SrmB	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236877
NZ_CP017961.1\|WP_005752328.1\|976615_977635_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|131470
NZ_CP017961.1\|WP_016533975.1\|965449_968353_-\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP017961.1\|WP_005724902.1\|980252_980864_+\|high-frequency-lysogenization-protein-HflD	unknown	unknown	gnl\|CDD\|225467
NZ_CP017961.1\|WP_005752891.1\|959802_961110_+\|toxin-HipA	unknown	unknown	gnl\|CDD\|377920
NZ_CP017961.1\|WP_005752327.1\|974962_976387_-\|PTS-sucrose-EIIBC-component	unknown	unknown	gnl\|CDD\|131051
NZ_CP017961.1\|WP_005752316.1\|963641_964070_-\|DUF2489-domain-containing-protein	unknown	unknown	gnl\|CDD\|378470
NZ_CP017961.1\|WP_005752329.1\|977660_979103_-\|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl\|CDD\|224536
NZ_CP017961.1\|WP_005719267.1\|982617_984204_+\|L-lactate-permease	unknown	unknown	gnl\|CDD\|224535
NZ_CP017961.1\|WP_005752326.1\|973324_974371_-\|lipopolysaccharide-heptosyltransferase-II	unknown	unknown	gnl\|CDD\|182835
NZ_CP017961.1\|WP_005752321.1\|968628_969333_+\|nicotinamide-riboside-transporter-PnuC	unknown	unknown	gnl\|CDD\|225742
NZ_CP017961.1\|WP_005752325.1\|972362_973328_-\|lipopolysaccharide-heptosyltransferase-RfaC	unknown	unknown	gnl\|CDD\|236809
NZ_CP017961.1\|WP_005752330.1\|979140_980067_-\|aminoimidazole-riboside-kinase	unknown	unknown	gnl\|CDD\|236514
NZ_CP017961.1\|WP_005752888.1\|961111_961447_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP017961.1\|WP_005752317.1\|964075_964645_-\|Der-GTPase-activating-protein-YihI	unknown	unknown	gnl\|CDD\|367878
NZ_CP017961.1\|WP_005724904.1\|980891_982259_+\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|236452
NZ_CP017961.1\|WP_005752318.1\|964708_965368_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659

Protein	Function_ID	Function_description	E-value
NZ_CP017961.1\|WP_005736824.1\|974439_974847_-\|copper-chaperone-PCu(A)C	gnl\|CDD\|225403	COG2847, COG2847, Copper(I)-binding protein [Inorganic ion transport and metabolism].	9.84673e-43
NZ_CP017961.1\|WP_005752314.1\|961542_962211_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|380324	cd02149, NfsB-like, nitroreductase similar to Escherichia coli NfsB. NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family includes FRase I in Vibrio fischeri, wihich reduces FMN into FMNH2 as part of the bioluminescent reaction. The family also includes oxygen-insensitive nitroreductases that use NADH or NADPH as an electron donor in the ping pong bi bi mechanism. This type of nitroreductase can be used in cancer chemotherapy to activate a range of prodrugs.	2.30268e-75
NZ_CP017961.1\|WP_005752322.1\|969380_970094_-\|tRNA1(Val)-(adenine(37)-N6)-methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	4.51997e-92
NZ_CP017961.1\|WP_005752323.1\|970205_971534_+\|ATP-dependent-RNA-helicase-SrmB	gnl\|CDD\|236877	PRK11192, PRK11192, ATP-dependent RNA helicase SrmB; Provisional.	0
NZ_CP017961.1\|WP_005752328.1\|976615_977635_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|131470	TIGR02417, Fructose_repressor_Catabolite_repressor/activator., D-fructose-responsive transcription factor. Members of this family belong the lacI helix-turn-helix family (pfam00356) of DNA-binding transcriptional regulators. All members are from the proteobacteria. Characterized members act as positive and negative transcriptional regulators of fructose and sucrose transport and metabolism. Sucrose is a disaccharide composed of fructose and glucose; D-fructose-1-phosphate rather than an intact sucrose moiety has been shown to act as the inducer. [Regulatory functions, DNA interactions].	0
NZ_CP017961.1\|WP_016533975.1\|965449_968353_-\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP017961.1\|WP_005724902.1\|980252_980864_+\|high-frequency-lysogenization-protein-HflD	gnl\|CDD\|225467	COG2915, COG2915, Uncharacterized protein involved in purine metabolism [General function prediction only].	7.18065e-110
NZ_CP017961.1\|WP_005752891.1\|959802_961110_+\|toxin-HipA	gnl\|CDD\|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	4.63311e-23
NZ_CP017961.1\|WP_005752327.1\|974962_976387_-\|PTS-sucrose-EIIBC-component	gnl\|CDD\|131051	TIGR01996, Includes:_Phosphotransferase_enzyme_IIB_component, PTS system, sucrose-specific IIBC component. This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).	0
NZ_CP017961.1\|WP_005752316.1\|963641_964070_-\|DUF2489-domain-containing-protein	gnl\|CDD\|378470	pfam10675, DUF2489, Protein of unknown function (DUF2489). This is a bacterial family of uncharacterized proteins.	2.02578e-48
NZ_CP017961.1\|WP_005752329.1\|977660_979103_-\|glycoside-hydrolase-family-32-protein	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	1.52017e-174
NZ_CP017961.1\|WP_005719267.1\|982617_984204_+\|L-lactate-permease	gnl\|CDD\|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	2.44663e-166
NZ_CP017961.1\|WP_005752326.1\|973324_974371_-\|lipopolysaccharide-heptosyltransferase-II	gnl\|CDD\|182835	PRK10916, PRK10916, ADP-heptose--LPS heptosyltransferase RfaF.	0
NZ_CP017961.1\|WP_005752321.1\|968628_969333_+\|nicotinamide-riboside-transporter-PnuC	gnl\|CDD\|225742	COG3201, PnuC, Nicotinamide mononucleotide transporter [Coenzyme metabolism].	9.77787e-73
NZ_CP017961.1\|WP_005752325.1\|972362_973328_-\|lipopolysaccharide-heptosyltransferase-RfaC	gnl\|CDD\|236809	PRK10964, PRK10964, lipopolysaccharide heptosyltransferase RfaC.	0
NZ_CP017961.1\|WP_005752330.1\|979140_980067_-\|aminoimidazole-riboside-kinase	gnl\|CDD\|236514	PRK09434, PRK09434, aminoimidazole riboside kinase; Provisional.	0
NZ_CP017961.1\|WP_005752888.1\|961111_961447_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.65249e-05
NZ_CP017961.1\|WP_005752317.1\|964075_964645_-\|Der-GTPase-activating-protein-YihI	gnl\|CDD\|367878	pfam04220, YihI, Der GTPase activator (YihI). YihI activates the GTPase activity of Der, a 50S ribosomal subunit stability factor. The stimulation is specific to Der as YihI does not stimulate the GTPase activity of Era or ObgE. The interaction of YihI with Der requires only the C-terminal 78 amino acids of YihI. A yihI deletion mutant is viable and shows a shorter lag period, but the same post-lag growth rate as a wild-type strain. yihI is expressed during the lag period. Overexpression of yihI inhibits cell growth and biogenesis of the 50S ribosomal subunit. YihI is an unusual, highly hydrophilic protein with an uneven distribution of charged residues, resulting in an N-terminal region with high pI and a C-terminal region with low pI.	8.94153e-60
NZ_CP017961.1\|WP_005724904.1\|980891_982259_+\|adenylosuccinate-lyase	gnl\|CDD\|236452	PRK09285, PRK09285, adenylosuccinate lyase; Provisional.	0
NZ_CP017961.1\|WP_005752318.1\|964708_965368_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	5.11158e-102

>NZ_CP017961.1|WP_005752323.1|970205_971534_+|ATP-dependent-RNA-helicase-SrmB
MTLATFQDFDLAPALLKALAKKGYTRPTAIQQETIPAAMEQRDVLGSAPTGTGKTAAFLLPAIQHLLDYPRRKPGAPRILILTPTRELAMQVAEQAESFAEFTNLSIATITGGVAYQNHGEIFNSNQDIVVATPGRLLQYIKEENFDCRSVEILIFDEADRMLQMGFGQDAEKIAAETRWRKQTLLFSATLEGELLVDFASRLLTDPLQIDAEPSRRERKKIQQWYYHADSNEHKIKLLARFIDEEQVSRGIVFVRRREDVRELSETLRKRGIRSTYLEGEMAQTQRNNAIDKLKNGIVTVLVATDVAARGIDIEDVSHVMNFDLPYSADTYLHRIGRTARAGKKGVAVSFVEAHDYKLLGKIKRYTQELLKARIIEGLAPRTKAPKEGEVKTVSKKQKARIKAKREEKQKQEQKKKVKLRHKDTKNIGKRRKSNTLPANAE
>NZ_CP017961.1|WP_005752322.1|969380_970094_-|tRNA1(Val)-(adenine(37)-N6)-methyltransferase
MSAKQNGFTFKQFHIEHHCCAMKVGTDGILLGAWADVSQAERILDLGTGTGLIALMLAQRSTKESEIHAVELEQAAYLQAQANIHASPWAQRVHVYQQDAAEFCRNAVNKFDLIVANPPYFPQGVDCATPQRDLARYTATHRHVDWLNWASHCLSEQGKISMVLPFEAGETLLKQTALYCIARCEVITKKGKAPQRLLLTFSLQAQPLQPSQLIIYDESNRYHPDFIGLTKDFYLAF
>NZ_CP017961.1|WP_005752321.1|968628_969333_+|nicotinamide-riboside-transporter-PnuC
MNLQAVKNEFLGGWKPFEVAWLSLFLIAQIVIYIQNPDSILGMISGISGILCVVFVSKGKVSNYFFGLIFAYTYFYVAWQANYLGEMNTVLYVYIPAQFIGYFLWRENLQKGSEGAESVIAKSLTLKGWAIVLGTITIGTLLFVQALNAAGGSSTGLDGLTTVIVVVAQLLMILRYREQWLLWIALNVISIVLWTQAKEGSLAMVTMYSAYLLNSLYGYYNWTKLEKTHRQSVQ
>NZ_CP017961.1|WP_016533975.1|965449_968353_-|RNA-polymerase-associated-protein-RapA
MTFAVGQRWMSESENNLGLGLIVAIDMRTVTILFPASEEQRIYALNSAPLTRVLFQIGDEIVHHEGWKGNVLDILENNGVAFYLLKRQDNGEEITIQERDIAHQMTFSKPQDRLFTTQIDRNEHFTLRYQALTHQQAQFQSPLRGLRGIRAGLIPHQLHIAREVGQRTAPRVLLADEVGLGKTIEAGMILQQQLFAEKVERVLIIVPETLQHQWLVEMLRRFNLHFALFDEERCADFEDPASALWINPFSTESQIICALDWLCEKPKRVEQLLEAGFDMLIVDEAHHLGWSEHNPSLEYQLVEQLARQIPAVLLLTATPEQLGQESHFARLSLLDPDRFYDYQAFVQEQQQYQPVADAVQSLLADKPLSAVEKNHIADLLSEQDVEPMLKVIDSQAHDEQKALARQELIDNLIDRHGTSRVLFRNTRQGVKGFPHRTYNQITLELPKQYNNAANVLAMLGEKSENDSFYPEQMFQKLNPDARWWEFDPRLAWLITFLKNHREEKVLVICRHANTAIQLEQALREKEAIRAAVFHEKLSIVERDRAAAYFAQQEDGAQVLLSSSIGSEGRNFQFASHLVLFNLPDDPDLLEQCIGRLDRIGQSRDIQIHVPCFADTAQVVLARWYHEGLNAFEETCPMGMTLFETHQTQLNKFLQKPTALEGFAEFVSLTRKQQYELKQALEKGRDRLLELNSNGGEQAQQLATDIAEQDGTTELVNFTLNLFDIIGVDQEDLGEKSIVITPASNMLVPDFPGLKEEGATVTFDRQLSLAREDVEFMSWDHPLIRHGIDLITSGDIGKSAVSLLINKALPAGTLLLEMIYVVEAQAPKGLQLTRFLPPTPIRLLLDQKGNNLAEQVSFNALQKQLKPIGKNMANKVVKMVRPNIEQLVKLSEQKIVAQAQQIIHNAQQLADQTLSAELNRLTALQAVNKNIRQDEVDALENIRSQSLAQLQQATWRLDSLRVIVSNKE
>NZ_CP017961.1|WP_005752318.1|964708_965368_-|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MALISYTPPTDPYLDIMHYDDHFVVINKPSGLLSVPGNQPQYYDSAMSRVKEKYGFCEPAHRLDMSTSGLILFALSKAADRELKRQFREREPKKHYQALVWGHLEEDQGEVNLPLICDWENRPRQKICFERGKPALTLYEVLARYPNNTTRVKLTPITGRSHQLRLHMLALGHPILGDKFYAPPQAKALSPRLCLHAEQLAFRHPITQEWLSFSAPPAF
>NZ_CP017961.1|WP_005752317.1|964075_964645_-|Der-GTPase-activating-protein-YihI
MARKKKTRRVSDIMPVRKVDKKVELPKGKQGKKLTRYELDAKAREDKKKKKRKGLASGSRHSATENNNNHQALAKKDPRLGSRKKVPLIVEFVNKPEKGMTIPPMKVEEKVAKPDPMLELEQLENNECLNQLLDALDAGKTLSAEDQQFVDDCLDRIAQLMDELGISEDDDPEEDLLRTFEKIDINQFR
>NZ_CP017961.1|WP_005752316.1|963641_964070_-|DUF2489-domain-containing-protein
MWTNILLILAVLVIVAMASYAGYLLLALQKQKKAIANMRTARSQRLTESIVIIAKAMQNGDCNHSEGVIRLKMLLDPLGKKLKNYQAMYQLYEVVMDMPTHEKRHELKKNERMRLDLQRESAEAELEQKIRLELQQLLIDMK
>NZ_CP017961.1|WP_005752314.1|961542_962211_-|NAD(P)H-dependent-oxidoreductase
MSISKTDILNAFHFRHACKAYDPSKKISEEDFRFILETGRLSPSSFGFEPWKFLVIENPKIKALISDTAWGAKDKVVDCSHFVVVLVRQPETLLADGEYVQHMMRDVHHIREEMRKIRQNFYRTFSEQDFALTENPKAFYDWACRQSYIALANMLTSAAMIGIDSTPIEGFPLEKMDHIFVEQGLYDPKTYKLSVMIAFGYRLNEPKAKTRQAFDDVVEWVR
>NZ_CP017961.1|WP_005752888.1|961111_961447_+|helix-turn-helix-transcriptional-regulator
MQITRRNASTKGASVAEIDRKKVRNEIIQAMLMGELSQGEALRKLRIEMFGINQQHYIQLVKVSRQTLSNIENDKGNYSVETINKVFKPFGLELGLVPVSKALLKELFSTA
>NZ_CP017961.1|WP_005752891.1|959802_961110_+|toxin-HipA
MEKLTLQIYLEQAWCDLAFLYFDSETYQLCNFEYLTDYVVQHYGKTGEHAVSLNYPVNVFIDDTTSLWSWLSDIAPAGASRRYWLEALDIKQESEEKQQFLLLKHAAISPIGNLRIKDAVPEQVEVRLFDLDKAKDRQSDFLEYVNQSGAMVGGATGAGGEAPKLLLKRRENQVWIDNQQQGQDQDVSYLVKYPRGNYSPIDCDILRAEYHYYQELAQLGFDTIDTTRMRLEEGKRYPSLWLPRFDIVQREGKTHRLAFESVYSLLQKQGGVLDHETTLRQLIERISTARLQFAQTDFVIEWVKRDLLNIAFGNSDNHGRNMAFLRDEQRIWLAPIYDFAPMRADPEGIIRTTTWQTKGEYPQEFAGEYHFERIAEVLADLVEPTLLMQELRRLAGSLVDLKSRLVQRNLPQSILDFPAIGFDYLPEKLKKWGLI
>NZ_CP017961.1|WP_005752325.1|972362_973328_-|lipopolysaccharide-heptosyltransferase-RfaC
MKICLVKTSSMGDILHSLPALTDAQRAIPNLQVDWVVEESFAEIPHWHSAVRQVIPIALRRWRKTPFTALTRKQWKTYRTLLQSEQYDAVIDAQGLLKSALFATRLARGTRHGYDRHSIREPIAACFYDKKYAISYQQHAVERIRQLFAQSLNYPLPHTQGDYGIARHFPQHAQTMPYVLFFHGTTRQDKFLPDRQWRTLAEKLTAQGIQIHVPWSNPQEKQRAERIAQGLDLVTILPKSTLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGATDPKLIGSYGKNQYYLVAESMDKIDADEIFQKLTALLSLNTI
>NZ_CP017961.1|WP_005752326.1|973324_974371_-|lipopolysaccharide-heptosyltransferase-II
MHILIIGPSWVGDMMMSHSLYQTLKQQYPQCEIDVMAPNWCKPLLERMPEVRQAITMPLGHGAFALGDRYRLGKALRHQYDMAIVLPNSLKSAFIPFFAKIPLRRGWKGESRYLFLNDLRSNKKDYPMMVQRYIALAFEKGAVPKAEDLPRPVPYLTVDPVTQQHTLKKFEKQTALISPRPSIGFCPGAEFGPAKRWPHYHYAKLAEMLIQQGYALRLFGSAKDETVGEEIRQALPETMRHFCINLAGQTSLNEAVDLIADCTAIVTNDSGLMHIAAAVQRPLVALYGPTSPTYTPPLSEKAVIIRLIEGDLIKVRKGKDSDEGYHQSLIDIQPELVFDKLTGLLANT
>NZ_CP017961.1|WP_005736824.1|974439_974847_-|copper-chaperone-PCu(A)C
MKSLTQLLFILTALLPTSLFAHIHVEQAQMFSAKAGEPSAIFMNIHNTGNEDVSLALVQSDIRADIVLHGTQHGKMIEVTGINLPAHQMTALKRGGLHIMVFNVEQDLNVGDSFPLRLLFDNGEIMHIEAKIIQY
>NZ_CP017961.1|WP_005752327.1|974962_976387_-|PTS-sucrose-EIIBC-component
MNFSQIAQQVIDKLGGKDNISAAAHCATRLRIVVKNENLIDKKGIENIEGVKGQFAVAGQYQIIFGSGTVNKVYAALSKLLGIGDMTTSEVAAAGTEKQGLLQRLVKGLADIFVPIIPAIVAGGLLMGIHSMLTAKGFFVEEKNVVDLYPAIADLVDFINTIANAPFVFLPVLLGFSATRKFGGNPFLGAALGMLLVHPALSDGWNYALTLAKGNIQYWHIFGLEIERVGYQGTVIPVLVASWVLATLEKNLRKVVPSFLDNLITPLFALFITGLLAFTVIGPIGREAGSLISTGLTWLYDTLGFVGGAIFGTLYAPIVITGMHQTFIAVETQLLAEVARTGGTFIFPIAAMSNIAQGAACLGAAYVMKDAKVRGIAVPSGISALLGITEPAMFGVNLRYRYPFISAMIGAGISSAVIALFNVKAIALGAAGLPGIPSIKPDSLAMYCVGMLISASIAFTLTVILGKRAQLKAE
>NZ_CP017961.1|WP_005752328.1|976615_977635_-|LacI-family-DNA-binding-transcriptional-regulator
MSITNKKRITLSDIAKCCGLSTTTVSMILNNRGEEFKIKAETCQRVKAIAEQQGYRANVYAKSLKMQRSNVIGFVIPDLTNYGFACTAKILEKQCRENGLQLIIACSDDNPQQEKLAIERLLDRQIDFLITAPTHQDPSYYQKIGQHTPILQLDRYVPDLALNYVISNDSEHITALICRLCDQYQLTEFMYFGGQRTLSPSESRLAGFLQGLKQANLNLKKEWILHRTYQPESGYQMLAETEAKLGRLPQAIFTASYTLLEGVLRYLTEQKKMDLLLNRQLHLATFDDHDILNALPFHIHSIKQNHPQLAQQIFQHIMRYFAGKKSPNQKIDCDVIYRD
>NZ_CP017961.1|WP_005752329.1|977660_979103_-|glycoside-hydrolase-family-32-protein
MYIFNQGKYKSLHAQQVGELAQIRQHVLRDTQFRPTYHLAPETGLLNDPNGLVFDGEKYHIFYQWFPYAAIHGMKHWKHFITYDFHHFQAADPLIPDELFESHGCYSGGALLWQDQIVAFYTGNTRNAENQRIPHQNIAIFKKDGTLLKKRCLLNQAPTGYTEHVRDPKPFITEEGKIRFILGAQREDLSGTALIYEMTDLDATPQLIGEFKLPDFDNQQVFMWECPDLLKLQEQDLFLWSPQGKAQKTYCFQNHYHATYALGQYANLHFSAQHIEELDYGFDFYAPQSIQGSEGIYYAWVGLPDLTYPMDEYQWHSMLSLPRQFSIQQGILYQRPIPQVYDQCLPAHKYWVEDKQQIPHLDRSYVAFDAENQPFTLRFFTNQRGQQLILRYQNGILTLDRTYTTQTALMQQFGEQRHCILPQLNHVEIFFDRSVVEIFLNQGEKVMTSRFFIADRENALDSSRPLCVSVAELKPIILTP
>NZ_CP017961.1|WP_005752330.1|979140_980067_-|aminoimidazole-riboside-kinase
MGKIWVLDDAVVDLIPEGENTYLRCAGGAPANVAVGIARLGATTGFIGRVGDDPLGRFMLNKLQQENVCTQYMHLDPKQRTSTVIVDLKEGERSFTFMVNPSADQFLELSDLPHFNPNDWLHCCSIALINEPSRSSTFAAIHRIKAEGGFFSFDPNLRESLWNSPAEMKTVVNQVVALADVLKFSEEELLFLTDSDTLSDATTKLTQHYPDKLIIVTLGKLGATYYLQGKSQLVSSKKALIPVDTTGAGDAFVSGLLFGISQVKNWQNPTALVEIIKQANACGALATTAKGAMSALPNKQQLDAFLAE
>NZ_CP017961.1|WP_005724902.1|980252_980864_+|high-frequency-lysogenization-protein-HflD
MANYYDITLALAGVCQAAKLVQQFAHEGQADQAAFETSLNTLLQIYPEDTLAVFGGKAQNLKLGLETLLEQMHGTGSDLSRYWISLLALESKLNKDPHAKAELARRIQYLPTQLEHYDLLDEQMLSTLASIYVDVISPLGKKIQVTGSTLYLQQLAMHHRIRACLLAGIRSAVLWRQVGGTKWQVLFSRRKIIAMAKQIYSSL
>NZ_CP017961.1|WP_005724904.1|980891_982259_+|adenylosuccinate-lyase
MQLNALTALSPIDGRYQDKVSSLRSIFSEFGLLKFRVTVEVRWLQKLAATDQIQEVSLLSQEANDYLNHIVENFSVQDAERIKEIERTTNHDVKAVEYFLKEKSEALPELAKISEFIHFACTSEDINNLSHALMLKTAREEVILPEWQNLIADISALANEYKTIPLLSRTHGQPASPSTIGKEMANVVYRLQRQFKQLQQIDILGKINGAVGNYNAHLSAYPDIDWHQFSEEFVTSLGLTWNPYTTQIEPHDYIAEFFDNVARFNTIIIDFDRDLWGYIALNHFKQRTIAGEIGSSTMPHKVNPIDFENSEGNLGLANAVMAHLGAKLPVSRWQRDLTDSTVLRNLGVGLGYCLIAYAATRKGISKLEVNEQHLRDELDQNWEVLAEPIQTVMRRYGIEKPYEKLKALTRGKRVDAEAMREFIETLDIPAQEKIRLQQMTPATYIGAAVELVEKL
>NZ_CP017961.1|WP_005719267.1|982617_984204_+|L-lactate-permease
MVFFLSILPIVLLIYLMVKRNSLPSYIALPLIAVLTYLLQAFYFGTDLTRLNANVIAGLIATQTPITIIFGAILFNRMMEVSGSTDVLRKWLANINPNPVAQIMIIGWAFAFMIEGASGFGTPAAIAAPILMGLGFKPLQVAMLALVMNSVPVSFGAVGTPTWFGFGPLGLSEDVVLEVGQKTAFIHFIAAFVIPVLALRFLVSWQQIKQNLVFIYISILACTIPYFLLAQVNYEFPALVGGAIGLFISILVANKGIGVSKTAQAEIQLEKVEFGVLVKALFPTMMLIAILIVTRIHQLGIKQLLNDATTWFSVSLGAFGEFKVSQALILSLNNILGQGINESYKTLYVPSLIPFIVTVIISIFVFKLNGAKAKTIAVSTYQQTKKPFFALLGALVMVKLMLVGNENYDSMVITIGKTFADVTGDKWVYFSSYLGAIGAFFSGSNTVSNLTFGGIQLSIAETTGMSVPLILALQSVGGAMGNMVCLNNIIAVCTVLNVSNQEGSILKRTVVPMFLYGVIAALVAVVIY

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Crispr_ID: NZ_CP017961_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017961_3

1490292-1490620

TypeI-F

Consensus_repeat	Method
GTTCACCATCGTGTAGATGGCTTAGAAA	PILER-CR
GTTCACCATCGTGTAGATGGCTTA	CRISPRCasFinder
GTTCACCATCGTGTAGATGGCTTAGAAA	CRT

5 spacers

cas6f,cas7f,cas5f,cas8f,cas1,cas3-cas2

The CRISPR arrays of NZ_CP017961_3

>merge|NZ_CP017961|3|1490292-1490620|PILER-CR,CRISPRCasFinder,CRT
GTTCACCATCGTGTAGATGGCTTAGAAATTTCCCGCTAATAGGTTTACCGTAAACTAAATGTTCACCATCGTGTAGATGGCTTAGAAATTTTATTTTACTACCTTGCACCAAGGTGTCAGGTTCACCATCGTGTAGATGGCTTAGAAAAGTGTAGTGGCCACAACATCTAAACGGCTCATGGTTCACCATCGTGTAGATGGCTTAGAAAACTACAGGGCACCTGTTAAAAGCTGGAAACAGGTTCACCATCGTGTAGATGGCTTAGAAATGTTTGGTGGTTAATCATATTGTTTTGGTGTTGTTCACCATCGTGTAGATGGCTTAAAAA

>NZ_CP017961|3|3|1490292-1490620|PILER-CR
GTTCACCATCGTGTAGATGGCTTAGAAA	TTTCCCGCTAATAGGTTTACCGTAAACTAAAT
GTTCACCATCGTGTAGATGGCTTAGAAA	TTTTATTTTACTACCTTGCACCAAGGTGTCAG
GTTCACCATCGTGTAGATGGCTTAGAAA	AGTGTAGTGGCCACAACATCTAAACGGCTCATG
GTTCACCATCGTGTAGATGGCTTAGAAA	ACTACAGGGCACCTGTTAAAAGCTGGAAACAG
GTTCACCATCGTGTAGATGGCTTAGAAA	TGTTTGGTGGTTAATCATATTGTTTTGGTGTT
GTTCACCATCGTGTAGATGGCTTAAAAA

>NZ_CP017961|3|3|1490292-1490616|CRISPRCasFinder
GTTCACCATCGTGTAGATGGCTTA	GAAATTTCCCGCTAATAGGTTTACCGTAAACTAAAT
GTTCACCATCGTGTAGATGGCTTA	GAAATTTTATTTTACTACCTTGCACCAAGGTGTCAG
GTTCACCATCGTGTAGATGGCTTA	GAAAAGTGTAGTGGCCACAACATCTAAACGGCTCATG
GTTCACCATCGTGTAGATGGCTTA	GAAAACTACAGGGCACCTGTTAAAAGCTGGAAACAG
GTTCACCATCGTGTAGATGGCTTA	GAAATGTTTGGTGGTTAATCATATTGTTTTGGTGTT
GTTCACCATCGTGTAGATGGCTTA

>NZ_CP017961|3|3|1490292-1490620|CRT
GTTCACCATCGTGTAGATGGCTTAGAAA	TTTCCCGCTAATAGGTTTACCGTAAACTAAAT
GTTCACCATCGTGTAGATGGCTTAGAAA	TTTTATTTTACTACCTTGCACCAAGGTGTCAG
GTTCACCATCGTGTAGATGGCTTAGAAA	AGTGTAGTGGCCACAACATCTAAACGGCTCATG
GTTCACCATCGTGTAGATGGCTTAGAAA	ACTACAGGGCACCTGTTAAAAGCTGGAAACAG
GTTCACCATCGTGTAGATGGCTTAGAAA	TGTTTGGTGGTTAATCATATTGTTTTGGTGTT
GTTCACCATCGTGTAGATGGCTTAAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017961.1\|WP_005721273.1\|1479906_1480176_+\|30S-ribosomal-protein-S15	unknown	unknown	gnl\|CDD\|180170
NZ_CP017961.1\|WP_005751242.1\|1497779_1498583_-\|inositol-1-monophosphatase	unknown	unknown	gnl\|CDD\|236753
NZ_CP017961.1\|WP_005751243.1\|1498796_1499513_+\|tRNA-(cytosine(32)/uridine(32)-2'-O)-methyltransferase-TrmJ	unknown	unknown	gnl\|CDD\|223639
NZ_CP017961.1\|WP_005751226.1\|1475764_1476256_+\|heme-utilization-cystosolic-carrier-protein-HutX	unknown	unknown	gnl\|CDD\|226244
NZ_CP017961.1\|WP_005751232.1\|1480312_1481425_-\|iron-sulfur-cluster-carrier-protein-ApbC	unknown	unknown	gnl\|CDD\|183270
NZ_CP017961.1\|WP_005725867.1\|1497125_1497716_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017961.1\|WP_017350190.1\|1486237_1487584_+\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	cd09675_cas8f_CAS-I-F	gnl\|CDD\|274203
NZ_CP017961.1\|WP_005721328.1\|1500103_1501318_+\|IscS-subfamily-cysteine-desulfurase	unknown	unknown	gnl\|CDD\|184450
NZ_CP017961.1\|WP_005751241.1\|1495128_1496985_+\|response-regulator	unknown	unknown	gnl\|CDD\|236842
NZ_CP017961.1\|WP_005751234.1\|1483788_1485948_+\|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL	unknown	unknown	gnl\|CDD\|236981
NZ_CP017961.1\|WP_005721379.1\|1502005_1502329_+\|iron-sulfur-cluster-assembly-protein-IscA	unknown	unknown	gnl\|CDD\|213674
NZ_CP017961.1\|WP_005721377.1\|1501549_1501936_+\|Fe-S-cluster-assembly-scaffold-IscU	unknown	unknown	gnl\|CDD\|183087
NZ_CP017961.1\|WP_005728799.1\|1489589_1490150_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09674_cas6f_CAS-I-F	gnl\|CDD\|274202
NZ_CP017961.1\|WP_016534211.1\|1491750_1495071_+\|type-I-F-CRISPR-associated-helicase-Cas3	cas3-cas2	cas3-cas2-CAS-I-F	gnl\|CDD\|187804
NZ_CP017961.1\|WP_005751239.1\|1490789_1491770_+\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|187849
NZ_CP017961.1\|WP_005751227.1\|1476271_1476787_+\|heme-utilization-protein-HutZ	unknown	unknown	gnl\|CDD\|200361
NZ_CP017961.1\|WP_005751236.1\|1487593_1488577_+\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09676_cas5f_CAS-I-F	gnl\|CDD\|274204
NZ_CP017961.1\|WP_005751233.1\|1481606_1483655_+\|methionine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234655
NZ_CP017961.1\|WP_005721326.1\|1499591_1500056_+\|Fe-S-cluster-assembly-transcriptional-regulator-IscR	unknown	unknown	gnl\|CDD\|273927
NZ_CP017961.1\|WP_005751237.1\|1488579_1489587_+\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|378222

Protein	Function_ID	Function_description	E-value
NZ_CP017961.1\|WP_005721273.1\|1479906_1480176_+\|30S-ribosomal-protein-S15	gnl\|CDD\|180170	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed.	3.85836e-50
NZ_CP017961.1\|WP_005751242.1\|1497779_1498583_-\|inositol-1-monophosphatase	gnl\|CDD\|236753	PRK10757, PRK10757, inositol-1-monophosphatase.	6.23789e-151
NZ_CP017961.1\|WP_005751226.1\|1475764_1476256_+\|heme-utilization-cystosolic-carrier-protein-HutX	gnl\|CDD\|226244	COG3721, HugX, Putative heme iron utilization protein [Inorganic ion transport and metabolism].	7.85086e-79
NZ_CP017961.1\|WP_005751232.1\|1480312_1481425_-\|iron-sulfur-cluster-carrier-protein-ApbC	gnl\|CDD\|183270	PRK11670, PRK11670, iron-sulfur cluster carrier protein ApbC.	0
NZ_CP017961.1\|WP_005751243.1\|1498796_1499513_+\|tRNA-(cytosine(32)/uridine(32)-2'-O)-methyltransferase-TrmJ	gnl\|CDD\|223639	COG0565, LasT, rRNA methylase [Translation, ribosomal structure and biogenesis].	5.62391e-118
NZ_CP017961.1\|WP_017350190.1\|1486237_1487584_+\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|274203	TIGR02564, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	8.34039e-124
NZ_CP017961.1\|WP_005721328.1\|1500103_1501318_+\|IscS-subfamily-cysteine-desulfurase	gnl\|CDD\|184450	PRK14012, PRK14012, IscS subfamily cysteine desulfurase.	0
NZ_CP017961.1\|WP_005751241.1\|1495128_1496985_+\|response-regulator	gnl\|CDD\|236842	PRK11091, PRK11091, aerobic respiration control sensor protein ArcB; Provisional.	0
NZ_CP017961.1\|WP_005751234.1\|1483788_1485948_+\|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL	gnl\|CDD\|236981	PRK11783, rlmL, bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL.	0
NZ_CP017961.1\|WP_005721379.1\|1502005_1502329_+\|iron-sulfur-cluster-assembly-protein-IscA	gnl\|CDD\|213674	TIGR02011, Protein_yfhF., iron-sulfur cluster assembly protein IscA. This model represents the IscA component of the ISC system for iron-sulfur cluster assembly. The ISC system consists of IscRASU, HscAB and an Isc-specific ferredoxin. IscA previously was believed to act as a scaffold and now is seen as an iron donor protein. This clade is limited to the proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	6.36459e-65
NZ_CP017961.1\|WP_005721377.1\|1501549_1501936_+\|Fe-S-cluster-assembly-scaffold-IscU	gnl\|CDD\|183087	PRK11325, PRK11325, scaffold protein; Provisional.	1.51567e-94
NZ_CP017961.1\|WP_005728799.1\|1489589_1490150_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|274202	TIGR02563, conserved_hypothetical_protein, CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	3.31771e-90
NZ_CP017961.1\|WP_016534211.1\|1491750_1495071_+\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	0
NZ_CP017961.1\|WP_005751239.1\|1490789_1491770_+\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187849	cd09718, Cas1_I-F, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	0
NZ_CP017961.1\|WP_005751227.1\|1476271_1476787_+\|heme-utilization-protein-HutZ	gnl\|CDD\|200361	TIGR04110, hypothetical_protein_VSWAT3_12502, heme utilization protein HutZ. Members of this family are heme utilization proteins, typically designated HutZ. They are members of the PPOX family (pfam01243) and, except for the lack of an N-terminal extension, are closely related to one form of heme oxidase (1.14.99.3), HugZ (TIGR04109). Members typically are found in a three-gene operon with radical SAM enzyme HutW and a protein of unknown function, HutX.	2.01653e-97
NZ_CP017961.1\|WP_005751236.1\|1487593_1488577_+\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|274204	TIGR02565, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	4.98451e-149
NZ_CP017961.1\|WP_005751233.1\|1481606_1483655_+\|methionine--tRNA-ligase	gnl\|CDD\|234655	PRK00133, metG, methionyl-tRNA synthetase; Reviewed.	0
NZ_CP017961.1\|WP_005721326.1\|1499591_1500056_+\|Fe-S-cluster-assembly-transcriptional-regulator-IscR	gnl\|CDD\|273927	TIGR02010, Putative_HTH-type_transcriptional_regulator, iron-sulfur cluster assembly transcription factor IscR. This model describes IscR, an iron-sulfur binding transcription factor of the ISC iron-sulfur cluster assembly system. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Regulatory functions, DNA interactions].	5.78928e-83
NZ_CP017961.1\|WP_005751237.1\|1488579_1489587_+\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0

>NZ_CP017961.1|WP_005728799.1|1489589_1490150_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MTTHYIELKAIPQMDMLQSEVIGHCMQILHQFLPHFEGRVGVAFPAYGLGRTLGGIVRLFANQEDCNQLHQQLLRSGLSDYALISEVSKTPLPTEYRSYSRVHRKGQSAIRRTEKRLKSQGRWDESIRADMQQRQQNVAFFPHCHLKSASTGQRFILAVKENRMSQSCVGVFNAYGLSNSATVPHF
>NZ_CP017961.1|WP_005751237.1|1488579_1489587_+|type-I-F-CRISPR-associated-protein-Csy3
MSKLSTPSVLAFERNLDISDAIFAQKDSKNDKDAPVPLRIREKSVRGTISNRLKNTITNDPAKLDAETEKANLQRVDVATLDDDKDTLVATFSVKVLPFTGRPNVCNDQNYQQQVMATVAQYLSEQGMDELAKRYATNIANARWLWRNRMGAEKIKIEVTCGENTIHFDDAKQFSLNHFDHQDDKIHQIAKEIKQGLLGEKFVILYVTAYANMGYGQEVYPSQELVLDNSTNNRKSKILYEINQKAGMHSQKVGNAIRTIDTWYAEEVAFPIAAEPYGAVTTLGTAFRQPKTKKNDFYTLFDNWLLKGEVPPVEQQHYVMSVLIRGGVFGASGKE
>NZ_CP017961.1|WP_005751236.1|1487593_1488577_+|type-I-F-CRISPR-associated-protein-Csy2
MFQTGFYILFDHIKVQSANAISGPLSYGFPALTGLTGAMHALNRKLTHHPVQFGGVMVACHDYELQTYQNSAFSDRTFKQTRNPIKRNGETASIIEEGKIHLDLSLVVEVHVQDEHVFEALTDKTSQASQDFLQTCKNLLWQQRIAGGSVLEIGNVQLFNLEEDQDIPLALMPAFVLMDAKQELVNITEELKTGLRIGQLDEEGNVQKSPVPSCPDATALDALLEMATVHHIPEHANATASAWQTYSVKKGRGWLVPLPVGYQAISPLFAPGQLQHCRTQQYPSQYVETLYSLGKWVFPLSLPENLSQCFWRYTALQNNLYLISQGE
>NZ_CP017961.1|WP_017350190.1|1486237_1487584_+|type-I-F-CRISPR-associated-protein-Csy1
MKLERIVDVLKLNSQLIKSEKLEKEEKKLQKTEEPTEREKILQKIAKINREYDHANLMSYRAGFMADQIKFGTHHPKGIHSSAKIECNTIYFDLKTPLPNTFCASQNIDNLTLDASGNAAALPLSKFFDIYVDDEKKIQLRDLLLQDHPVLDYCFAEDPELSVHYKKQFQKTLKSDFDNPISYEKCKQLLWVNSNSSVEDDDYTCLVPLYPSSLIYNFYQKVQFIKYNSDENKLNRENRKKSNVVQKPYKNLVDLAVFKVGGSNPQGVGQLASIQGGRNYLLSSLPPIMPSSRYFRLSPLQTTIFNDRLAYACRYGLRQLFEVVEARKNGYQVRDSRIDALNNILRTFLFHANLLQKQPAGWSKDSQLEMCEKYWLDPKRVHLPDEEAFRAEYEKGEWVAEVERRFALWLNKCLQKRFPHIAKDFDDAEYHEWRRNIRRTLRYRLRHP
>NZ_CP017961.1|WP_005751234.1|1483788_1485948_+|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL
MKQLFATTARGFEELLKVELTDLGAMDCQITQGGVHFHADEETQYRVLLWTRLASRILLPIVTCKVYSDLDLYSAVVGQNWLDYFDEKAHFMVDFNGTNREIRHTQFGAMRVKDGIVDYFERVGKPRPNVDKSQPDIRIHAYLNREELVISLDLSGDALHMRGYREDTGKAPLRETLAAAIVLRSGWQLGTPLVDPMCGSGTLLIEAAQMQANIAPQLHRLHWGFDFWKGHNQQAWDKVKGEAIELAQQTFNQNQKANFYGCDLDHRVLQKAKRNAQNAGVAHLIQWQQGDVAALKNPFVEEKGTVICNPPYGERLGTTPALIALYSVFGQRLKQQFADWNVSIFSGEPALLDCLRLRSHRQFKAKNGPLDCVQKNYHINARATASDENTQNLPEIDRTLTSAQVAVDFANRLQKNSKKIEKWAKQQGINAYRLYDADLPEYNLAVDRYDDHIVVQEYAAPKNIDENKARQRLLDAVTATLQVTGVETNKLILKVRQKQKGTNQYEKLANKGDYFYVNEYGAKLWVNLTDYLDTGLFLDHRLTRKMLGEMAKGKDVLNLFAYTGSATVHMALGGAKSTTTVDMSNTYLNWAEQNLLLNDLEGKQHKLIQADCLQWLARCDRQFDLIFVDPPTFSNSKRMEDSWDVQRDHIKLMTQLKRILRPNGTIVFSNNKRGFKMDVEGLETLGLSAVDITAKTLPLDFERNKQIHNCWVVRLKADL
>NZ_CP017961.1|WP_005751233.1|1481606_1483655_+|methionine--tRNA-ligase
MANSARDILVTCALPYANGAIHLGHLLEHIQADIWVRFQRMRGHKVHFICADDAHGTPIMLNADKLGITPEALIARSKADHVADFEGFNISYDNYHSTHSPENEALTAEMYKKLRANGFIKSRTISQLFDPEKGMFLPDRFVKGTCPKCKAEDQYGDNCEVCSSTYSPTELINPRSVVSGATPVLKESEHFFFDLPAFEGMLKAWIKSGSLQPEIANKMQEWFESGLQQWDISRDAPYFGFKIPDTEDKYFYVWLDAPIGYMASFKNLCDKTGLNFDDFWKKDSSAELYHFIGKDIVYFHSLFWPAMLDGCDLRKPTNVFAHGYVTVNGVKMSKSRGTFIQASTYLRHLAPEYLRYYYAAKLNNRIEDLDLNLEDFVQRLNADVVNKFVNLASRSAGFITKRFDGKLSAEIAEPELLAEFVEKAAQIATYYEEREFGKVVREVMQLADKANKYIDDKAPWVMAKEEGREAELQAVCSMALQLFRLLAIYLKPVIPQIIARAEAFLQDELTWESLNRPLLNHAILPFKALAQRLDPKQIEAIVNETKEQFVAQQALEQKNSAKAEPASQVEPIAETISIEDFAKLDLRVAKVMKCEAVPESNKLLRFELDLGDHTRQVFSGIKEAYNNPAELEGRFVVVIANLAPRKMRFGVSEGMILSAGTGGDDLFLLNADQGVKPGMQVK
>NZ_CP017961.1|WP_005751232.1|1480312_1481425_-|iron-sulfur-cluster-carrier-protein-ApbC
MGILFSDSLTDSQKQAIQNAFQQFQHPSLQKDLVSLNAIKKIEKGGETLRIEISMPFAWNTAFEQHKSTLSAELLTLAECKDIKWQLNYQIATLKRANSHPAVKGVKNIIAVTSGKGGVGKSTISVNLALALQRQGARVGILDADIYGPSIPHMLGVADQRPTSPDNQHITPIQAHHIFANSIGFLMEPDNATIWRGPMASSALSQLLQETLWPDLDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDIALLDAIKGVAMFERVSVPVLGIIENMSMHICSNCGHQETIFGTGGAERIAQKYNVKVLGQQALQIRLREDLDKGIPTVVAAPESDTAQSFMQLAEKVATELYWQGSVIPSEIMFKEVK
>NZ_CP017961.1|WP_005721273.1|1479906_1480176_+|30S-ribosomal-protein-S15
MSLSTEKKAAIVAEFGRDAKDTGSSEVQIALLTAQINHLQSHFATHKKDHHGRRGLLRMVSRRRKLLDYLKRTNLELYTSTIARLGLRR
>NZ_CP017961.1|WP_005751227.1|1476271_1476787_+|heme-utilization-protein-HutZ
MTTNRQEVLQNRLGPEIQELKAQCKTVMLATVGEDGNPNVSYAPFAINNGEYQVFISTIARHARNLQEVPKVSLMLIEDESQSRQIFARRRLSFDAVARVVERESEEWHSGVEALKARHGALMDELSRMKDFHLFSFKPSQGLFVKGFGQAFQVSNDDLVSFVHLVEGHQE
>NZ_CP017961.1|WP_005751226.1|1475764_1476256_+|heme-utilization-cystosolic-carrier-protein-HutX
MMLKAQIADYITQNPMAITLDMASHFGKPEGEILCALPDEFVRVFPGERAEEVLAEISSWGIFTTIIEKEGSIFEIKDRFPTGMVGRGYYNLNMKDEEGTLHGHLKLDNISKIAFMSLPFRGKESYNIAFIANNGQTIFKVYLGRDAERQLFPEQVQKFKAFI
>NZ_CP017961.1|WP_005751239.1|1490789_1491770_+|type-I-F-CRISPR-associated-endonuclease-Cas1
MRKTPYIPSSDLKTIMHSKRANIYYLEHCRVLLNGGRVEYVTDEGRESFYWNIPIANTSCLLLGSGTSITQAAMRELSKAGVMVGFCSGGGTPLFNGTEAEIGCEFFSPQSEYRPVMYLQQWCKFWFDDEKRLAVAKALQQQRLALLEPIWSKLEWVYSCEKLTALVTQYQQEFAQAAHSQALLAAEGRLTTKLYALANQATMNEPDFKRSERGKSIDLVNQFLDHGNYLAYGLGATACWVLGLPHGLAVLHGKTRRGGLVFDAADIIKDSMILPQAFISAQNGDSEKEFRQACIQNLLRFGALDIIIERLQQLALQGASDEYFAG
>NZ_CP017961.1|WP_016534211.1|1491750_1495071_+|type-I-F-CRISPR-associated-helicase-Cas3
MNILLVSQCQKNALTETRRILDQFAERCGDRVWQTAITQAGLETLYKMLRQTARKNTAVACYWTHRKNSAELLWIVGDRRQFNDQGRVPTNRTQRNILRAEEEMAWQDAYSLQILTALSALLHDVGKSSVGFQAKLDKTKNAPRVADSYRHEWISARLFEAMIEGCQTDQAWLERLANWQVFEETNPIWFSKIIQDRPNENHFSDFAYLPPLARRVIWLITSHHRLPFTHDISRSQDCIKNLRKYAKLTFESLFKAYKPAVGWVSNGAEHPTPQAFWQFQRVATQSQAWQKHMARWAKKALNHPALFSVSENADPFLLLLARLCLMTGDHYYSAQDQNEKLGELNFPLLANTYRENHQPKQRLDEHLIGVCQTAVRFARLLPKFPRELPRIKQHKPFVQLAKDRFAWQNKAVNVARLLQQTSESQGFFGVNMASTGCGKTLANAKMMYALNDSKQGARFTIALGLRVLTLQTGSALKKRLHLSDQDLAVLVGGSAVKKLYALQQEKQNQLAQQGSESAEDWLEDIQVEGATYIESAVENEAVLSFLSKDDKTKKLLYAPIVSCTLDHLISASESVRGGHHIVPILRLLTSDLILDEPDDFAQEDLPALSRLVYLAGLFGSRVLLSSATLTPDFITGLFKAYQAGRKIYNQQKGIVAALPICCAWVDEFQQVQANCGQDEQFIQQHDEFVRKRAENLAKSPVRRQAEILSLPSLKPREGEDLHYGLLADTLLQKAMALHDLHGQTDPHSQKKVSVGLIRFSNIEPMIPLAKALFGLQASEKFADYQVHLCCYHSRQLLLLRSYLEEKLDKILDRHTPEQLFQHEEIALPMSQYKAKNHLFIVLGSPVTEVGRDHDYDWAIVDPSSMRSIIQLAGRVWRHRAEKVAEQPNIALLPINWRGLKVCYQQKDVIYHRPGFESHQHKLATHKLEQLISQRDLAHIQATPRIVKPEVLQASTQLADLEHHAIASLLNHPSENLVNLYWDPRYCNYLLANLPLMSEFRKSMAELEVVCVPDEDSHWGFGFYRAQKRDEETLSALPEIQYEPIQQDKQAIVQPWLVASLDTVLSELAEQLNVASPAEIAPTYLYASLPQYNEQLDWHYNEVYGFW
>NZ_CP017961.1|WP_005751241.1|1495128_1496985_+|response-regulator
MKNIKYFTQKYVDWVIRLGRLRFSILGVIVLAILALCTQALLSVFIIGEVDWMDMIRSIVFGLISAPFVIYFFTVLVEKLERSRLGLAKMVENLRKEVSERVLAEKKLSIALDNIEKTSRDKTRLMATISHELRTPLNGIIGLSRILLDEKLTETQQNYLKTIHVSAISLGHIFSDIIDLEKIDARRIELNAKAVELNSFLNDISNVARLLAQEKKLAFQLVTDKNLPTWFMVDYARLSQILWNLIGNAVKFTQEGRITLNVKRVSEYQISFSVSDTGIGIPANELPRVFEMYYQVQSSGHKPLGSGIGLAISQTIAQLMGGDLYATSEMGKGSCFTLMLPVKEVEKPVRVQNQMPSTLNILLVEDIEVNVVVAKSVLEKLGYVVDVAMTGQQAIEKFEQQYYDLLLLDIQLPDMSGFAVAKYLWEGYENGQYDFLPPLIALTANVMHDKKEYQAQGMDDVLRKPLSIEELTACLVEYFGHDVSLCLETPTTHQITQDATHFDVKMLSELVEMLGTDFVLKNLALFKETMPEYMQALMTAYSVYQQDESQKADVLSCAHKIKGAAASVGLKRIQQIAAQAQDSEQGEWTENIHDWVQQLAQYWLLDVEALERYLNKSV
>NZ_CP017961.1|WP_005725867.1|1497125_1497716_+|hypothetical-protein
MKIFAVLSAFLMPFVVPNTTVNGYKDLRFGMTIEQAKETKLCEDQWHLPADDDWRRVVRGYWVCDKFRFDDGYAVARLRFIGGQLKSIELKMPEYPKYPAELLLHVLEEKYGKTIEVEQRDLIEEDILQGKIRKRRKNESALLDTYQFAKGTVSLTLLTYNGIPQPAEIIYSAPELLLLEKKLEDRPQRRTLLRDL
>NZ_CP017961.1|WP_005751242.1|1497779_1498583_-|inositol-1-monophosphatase
MNPMLNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYPDHTIITEESGALEGKDSDIQWVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPIRNELFTAVRGEGAKINDMRLRVENKRDLAATVLTTGFPFKQTRLMPMQFAMMNNLIQDCADFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSGHLVAAAPRIVKEILNKIQPCLSDEFKK
>NZ_CP017961.1|WP_005751243.1|1498796_1499513_+|tRNA-(cytosine(32)/uridine(32)-2'-O)-methyltransferase-TrmJ
MLENIRIVLVETSHSGNIGSAARAMKTMGLNQLYLVAPKQPLDEHAIALSAGAEDVLKQAKIVASFDEAVADCALVVGTSARLRHLQNSLIEPRECGTHAIAYAKQAPVAIVFGRERIGLTNEELLKCRYHLTIPANPDYSSLNLAMAVQLICYELRLAFLSQQAMTESLSTIDNTYPTHTEIEHFFQHTERLYTALGFIQNQGVMPKLRRLYQRVQLEKNELNILRGMLTAVEKRLK
>NZ_CP017961.1|WP_005721326.1|1499591_1500056_+|Fe-S-cluster-assembly-transcriptional-regulator-IscR
MKLTSKGRYAVTAILDIALNSNRGPVSLSDISERQHISLSYLEQLFAKLRRHGLVKSVRGPGGGYQLGLPANRISVGMVINAVNENIDVTRCLGRGDCQEGTECLTHSLWKELSLRIEAFLNEITLEELVEKNRQKRATIEFRGDFDNLIILDN
>NZ_CP017961.1|WP_005721328.1|1500103_1501318_+|IscS-subfamily-cysteine-desulfurase
MKLPIYLDYAATCPVDERVAKKMMEYLTVEGNFGNPASRSHKFGWQAEEAVDVARNHIADLIGADSREIVFTSGATESDNLAIKGAAHFYQSKGKHIITCKTEHKAVLDTCRQLEREGFEVTYLNPKSDGLIDLEELKNAMRDDTILVSIMHVNNEIGVIQDIAAIGELCRARKILFHVDATQSVGKLPINLAELKVDLMSMSSHKLYGPKGIGALYVSRKPRVRLEAIIHGGGHERGMRSGTLPVHQIVGMGEAYRICKEEMASEMPRLKALRDRLYNGLKDIEETYVNGSMEHRLDSNLNISFNYVEGESLMMALRDIAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFTLGRYTTEEEIDYTIELVKNAVAKLRELSPLWDMFKEGIDLNTIEWTHH
>NZ_CP017961.1|WP_005721377.1|1501549_1501936_+|Fe-S-cluster-assembly-scaffold-IscU
MAYSNKVIDHYENPRNVGSLDKKDANVGTGMVGAPACGDVMQLQIKVSEEGIIEDAKFKTYGCGSAIASSSLITEWVKGKSLDEAQAIKNSQIAEELELPPVKVHCSILAEDAIKAAIADYKAKKEAK
>NZ_CP017961.1|WP_005721379.1|1502005_1502329_+|iron-sulfur-cluster-assembly-protein-IscA
MGISLTETAADRVRTFLANRGKGIGLRLGIKTSGCSGLAYVLEFVDELNPEDQVFEQHGVKIIVDAKSLVYLDGTELDFAKEGLNEGFKFNNPNVKDQCGCGESFHV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP017961_2	2.1\|971711\|32\|NZ_CP017961\|PILER-CR,CRISPRCasFinder,CRT	971711-971742	32	NZ_CP017961.1	468490-468521	0	1.0

1. spacer 2.1|971711|32|NZ_CP017961|PILER-CR,CRISPRCasFinder,CRT matches to position: 468490-468521, mismatch: 0, identity: 1.0

cggcactgagtgcgacaatagagccaactgac	CRISPR spacer
cggcactgagtgcgacaatagagccaactgac	Protospacer
********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017961_3	3.3\|1490440\|33\|NZ_CP017961\|PILER-CR,CRT	1490440-1490472	33	MH238467	Pasteurella phage Pm86, complete genome	23120-23152	1	0.97
NZ_CP017961_1	1.9\|192890\|29\|NZ_CP017961\|PILER-CR	192890-192918	29	MN694264	Marine virus AFVG_250M904, complete genome	16037-16065	5	0.828
NZ_CP017961_2	2.9\|972191\|33\|NZ_CP017961\|CRISPRCasFinder,CRT	972191-972223	33	NC_005329	Haemophilus ducreyi strain ATCC 27722 plasmid pNAD1, complete sequence	1750-1782	5	0.848
NZ_CP017961_3	3.8\|1490436\|37\|NZ_CP017961\|CRISPRCasFinder	1490436-1490472	37	MH238467	Pasteurella phage Pm86, complete genome	23120-23156	5	0.865
NZ_CP017961_1	1.1\|192876\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	192876-192905	30	MN694264	Marine virus AFVG_250M904, complete genome	16036-16065	6	0.8
NZ_CP017961_1	1.2\|192942\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	192942-192971	30	MN582082	Podoviridae sp. ctrTa16, complete genome	37740-37769	6	0.8
NZ_CP017961_1	1.5\|193140\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193140-193169	30	MN855679	Bacteriophage sp. isolate 244, complete genome	6911-6940	6	0.8
NZ_CP017961_1	1.6\|193206\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193206-193235	30	KX078568	Morganella phage vB_MmoP_MP2, complete genome	23068-23097	6	0.8
NZ_CP017961_1	1.9\|192890\|29\|NZ_CP017961\|PILER-CR	192890-192918	29	NZ_CP032629	Lactococcus sp. 1JSPR-7 plasmid unnamed2, complete sequence	2059-2087	6	0.793
NZ_CP017961_1	1.9\|192890\|29\|NZ_CP017961\|PILER-CR	192890-192918	29	NC_019351	Lactococcus lactis subsp. cremoris plasmid pAF22, complete sequence	19026-19054	6	0.793
NZ_CP017961_1	1.13\|193155\|29\|NZ_CP017961\|PILER-CR	193155-193183	29	MN855679	Bacteriophage sp. isolate 244, complete genome	6912-6940	6	0.793
NZ_CP017961_1	1.14\|193221\|29\|NZ_CP017961\|PILER-CR	193221-193249	29	KX078568	Morganella phage vB_MmoP_MP2, complete genome	23069-23097	6	0.793
NZ_CP017961_3	3.1\|1490320\|32\|NZ_CP017961\|PILER-CR,CRT	1490320-1490351	32	MN693409	Marine virus AFVG_25M351, complete genome	28924-28955	6	0.812
NZ_CP017961_1	1.1\|192876\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	192876-192905	30	NZ_CP032629	Lactococcus sp. 1JSPR-7 plasmid unnamed2, complete sequence	2058-2087	7	0.767
NZ_CP017961_1	1.1\|192876\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	192876-192905	30	NC_019351	Lactococcus lactis subsp. cremoris plasmid pAF22, complete sequence	19026-19055	7	0.767
NZ_CP017961_1	1.7\|193272\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193272-193301	30	NZ_CP027438	Escherichia coli strain 2012C-4221 plasmid unnamed1, complete sequence	72542-72571	7	0.767
NZ_CP017961_1	1.9\|192890\|29\|NZ_CP017961\|PILER-CR	192890-192918	29	NZ_CP016173	Bordetella flabilis strain AU10664 plasmid unnamed1, complete sequence	39118-39146	7	0.759
NZ_CP017961_1	1.10\|192956\|29\|NZ_CP017961\|PILER-CR	192956-192984	29	MN693535	Marine virus AFVG_25M313, complete genome	21500-21528	7	0.759
NZ_CP017961_1	1.14\|193221\|29\|NZ_CP017961\|PILER-CR	193221-193249	29	MK290739	Pectobacterium phage Q19, complete genome	22971-22999	7	0.759
NZ_CP017961_1	1.15\|193287\|29\|NZ_CP017961\|PILER-CR	193287-193315	29	AP019525	Tenacibaculum phage PTm5 DNA, complete genome	217893-217921	7	0.759
NZ_CP017961_1	1.15\|193287\|29\|NZ_CP017961\|PILER-CR	193287-193315	29	AP019524	Tenacibaculum phage PTm1 DNA, complete genome	215728-215756	7	0.759
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	MF919502	Mycobacterium phage Demsculpinboyz, complete genome	44697-44725	7	0.759
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	NC_009820	Mycobacterium phage Tweety, complete genome	47562-47590	7	0.759
NZ_CP017961_2	2.2\|971771\|32\|NZ_CP017961\|PILER-CR,CRISPRCasFinder,CRT	971771-971802	32	MG592553	Vibrio phage 1.187.O._10N.286.49.F1, partial genome	77213-77244	7	0.781
NZ_CP017961_2	2.10\|972252\|32\|NZ_CP017961\|CRISPRCasFinder	972252-972283	32	KM606997	Enterobacteria phage RB7, complete genome	22179-22210	7	0.781
NZ_CP017961_2	2.10\|972252\|32\|NZ_CP017961\|CRISPRCasFinder	972252-972283	32	KM606998	Enterobacteria phage RB9, complete genome	22179-22210	7	0.781
NZ_CP017961_1	1.1\|192876\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	192876-192905	30	NZ_CP034149	Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence	271203-271232	8	0.733
NZ_CP017961_1	1.1\|192876\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	192876-192905	30	NZ_CP016173	Bordetella flabilis strain AU10664 plasmid unnamed1, complete sequence	39118-39147	8	0.733
NZ_CP017961_1	1.2\|192942\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	192942-192971	30	MN693535	Marine virus AFVG_25M313, complete genome	21499-21528	8	0.733
NZ_CP017961_1	1.6\|193206\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193206-193235	30	MK290739	Pectobacterium phage Q19, complete genome	22970-22999	8	0.733
NZ_CP017961_1	1.7\|193272\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193272-193301	30	AP019525	Tenacibaculum phage PTm5 DNA, complete genome	217892-217921	8	0.733
NZ_CP017961_1	1.7\|193272\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193272-193301	30	AP019524	Tenacibaculum phage PTm1 DNA, complete genome	215727-215756	8	0.733
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	NZ_CP040721	Rhodococcus pyridinivorans strain YF3 plasmid unnamed2, complete sequence	141858-141887	8	0.733
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	MF919502	Mycobacterium phage Demsculpinboyz, complete genome	44697-44726	8	0.733
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	NC_009820	Mycobacterium phage Tweety, complete genome	47562-47591	8	0.733
NZ_CP017961_1	1.9\|192890\|29\|NZ_CP017961\|PILER-CR	192890-192918	29	NZ_CP034149	Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence	271204-271232	8	0.724
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	NZ_CP040721	Rhodococcus pyridinivorans strain YF3 plasmid unnamed2, complete sequence	141858-141886	8	0.724
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	NC_005017	Yersinia enterocolitica 8081 plasmid pYVe8081, complete sequence	44262-44290	8	0.724
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	NC_004564	Yersinia enterocolitica plasmid pYVa127/90, complete sequence	46285-46313	8	0.724
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	NC_019234	Yersinia enterocolitica (type O:8) plasmid pYV-WA314, complete sequence	46548-46576	8	0.724
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	NC_008791	Yersinia enterocolitica subsp. enterocolitica 8081 plasmid pYVe8081, complete sequence	44263-44291	8	0.724
NZ_CP017961_1	1.16\|193353\|29\|NZ_CP017961\|PILER-CR	193353-193381	29	NZ_CP009366	Yersinia enterocolitica strain WA plasmid unnamed, complete sequence	53302-53330	8	0.724
NZ_CP017961_2	2.2\|971771\|32\|NZ_CP017961\|PILER-CR,CRISPRCasFinder,CRT	971771-971802	32	AJ630128	Bacteriophage S-PM2 complete genome	89974-90005	8	0.75
NZ_CP017961_2	2.2\|971771\|32\|NZ_CP017961\|PILER-CR,CRISPRCasFinder,CRT	971771-971802	32	NC_006820	Synechococcus phage S-PM2, complete genome	89974-90005	8	0.75
NZ_CP017961_2	2.2\|971771\|32\|NZ_CP017961\|PILER-CR,CRISPRCasFinder,CRT	971771-971802	32	LN828717	Synechococcus phage S-PM2 spontaneous deletion mutant, complete genome	80432-80463	8	0.75
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	NC_005017	Yersinia enterocolitica 8081 plasmid pYVe8081, complete sequence	44262-44291	9	0.7
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	NC_004564	Yersinia enterocolitica plasmid pYVa127/90, complete sequence	46285-46314	9	0.7
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	NC_019234	Yersinia enterocolitica (type O:8) plasmid pYV-WA314, complete sequence	46548-46577	9	0.7
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	NC_008791	Yersinia enterocolitica subsp. enterocolitica 8081 plasmid pYVe8081, complete sequence	44263-44292	9	0.7
NZ_CP017961_1	1.8\|193338\|30\|NZ_CP017961\|CRISPRCasFinder,CRT	193338-193367	30	NZ_CP009366	Yersinia enterocolitica strain WA plasmid unnamed, complete sequence	53301-53330	9	0.7
NZ_CP017961_2	2.2\|971771\|32\|NZ_CP017961\|PILER-CR,CRISPRCasFinder,CRT	971771-971802	32	MN693355	Marine virus AFVG_25M40, complete genome	21056-21087	9	0.719
NZ_CP017961_2	2.2\|971771\|32\|NZ_CP017961\|PILER-CR,CRISPRCasFinder,CRT	971771-971802	32	CP052843	Bacillus phage Hybphi3Ts, partial sequence	22765-22796	9	0.719
NZ_CP017961_2	2.10\|972252\|32\|NZ_CP017961\|CRISPRCasFinder	972252-972283	32	NZ_CP013139	Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence	648421-648452	9	0.719
NZ_CP017961_2	2.10\|972252\|32\|NZ_CP017961\|CRISPRCasFinder	972252-972283	32	NZ_CP044084	Pseudomonas luteola strain FDAARGOS_637 plasmid unnamed1, complete sequence	87853-87884	9	0.719

1. spacer 3.3|1490440|33|NZ_CP017961|PILER-CR,CRT matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 1, identity: 0.97

agtgtagtggccacaacatctaaacggctcatg	CRISPR spacer
agtgtagtggccacaacatctaaacggctcatc	Protospacer
********************************

2. spacer 1.9|192890|29|NZ_CP017961|PILER-CR matches to MN694264 (Marine virus AFVG_250M904, complete genome) position: , mismatch: 5, identity: 0.828

atacatgctaatcaatttgataaggctgg	CRISPR spacer
ttagctgctaaacaatttgataaagctgg	Protospacer
 **  ****** ***********.*****

3. spacer 2.9|972191|33|NZ_CP017961|CRISPRCasFinder,CRT matches to NC_005329 (Haemophilus ducreyi strain ATCC 27722 plasmid pNAD1, complete sequence) position: , mismatch: 5, identity: 0.848

aagttgttatattaagcatgaagaaatgaaacg	CRISPR spacer
gagttgttatattaaacatgaagagatgaagct	Protospacer
.**************.********.*****.*

4. spacer 3.8|1490436|37|NZ_CP017961|CRISPRCasFinder matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 5, identity: 0.865

gaaaagtgtagtggccacaacatctaaacggctcatg	CRISPR spacer
ttccagtgtagtggccacaacatctaaacggctcatc	Protospacer
    ********************************

5. spacer 1.1|192876|30|NZ_CP017961|CRISPRCasFinder,CRT matches to MN694264 (Marine virus AFVG_250M904, complete genome) position: , mismatch: 6, identity: 0.8

atacatgctaatcaatttgataaggctgga	CRISPR spacer
ttagctgctaaacaatttgataaagctggt	Protospacer
 **  ****** ***********.*****

6. spacer 1.2|192942|30|NZ_CP017961|CRISPRCasFinder,CRT matches to MN582082 (Podoviridae sp. ctrTa16, complete genome) position: , mismatch: 6, identity: 0.8

ggtagataaaagttaaattcattgagttta	CRISPR spacer
agcagacccaagttaaactcattgagttta	Protospacer
.*.***.  ********.************

7. spacer 1.5|193140|30|NZ_CP017961|CRISPRCasFinder,CRT matches to MN855679 (Bacteriophage sp. isolate 244, complete genome) position: , mismatch: 6, identity: 0.8

tcaagttgccaattacagggaccaaaacgg	CRISPR spacer
tcaggttgccaattacagggatatgaatgg	Protospacer
***.*****************.  .**.**

8. spacer 1.6|193206|30|NZ_CP017961|CRISPRCasFinder,CRT matches to KX078568 (Morganella phage vB_MmoP_MP2, complete genome) position: , mismatch: 6, identity: 0.8

aggtacggtctcctgctggtacatatcgag	CRISPR spacer
aagtacggtctgctgccggtacatagttag	Protospacer
*.********* ****.******** . **

9. spacer 1.9|192890|29|NZ_CP017961|PILER-CR matches to NZ_CP032629 (Lactococcus sp. 1JSPR-7 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

atacatgctaatcaatttgataaggctgg	CRISPR spacer
atatatgctaatgaatttgataattatgc	Protospacer
***.******** **********   **

10. spacer 1.9|192890|29|NZ_CP017961|PILER-CR matches to NC_019351 (Lactococcus lactis subsp. cremoris plasmid pAF22, complete sequence) position: , mismatch: 6, identity: 0.793

atacatgctaatcaatttgataaggctgg	CRISPR spacer
atatatgctaatgaatttgataattatgc	Protospacer
***.******** **********   **

11. spacer 1.13|193155|29|NZ_CP017961|PILER-CR matches to MN855679 (Bacteriophage sp. isolate 244, complete genome) position: , mismatch: 6, identity: 0.793

tcaagttgccaattacagggaccaaaacg	CRISPR spacer
tcaggttgccaattacagggatatgaatg	Protospacer
***.*****************.  .**.*

12. spacer 1.14|193221|29|NZ_CP017961|PILER-CR matches to KX078568 (Morganella phage vB_MmoP_MP2, complete genome) position: , mismatch: 6, identity: 0.793

aggtacggtctcctgctggtacatatcga	CRISPR spacer
aagtacggtctgctgccggtacatagtta	Protospacer
*.********* ****.******** . *

13. spacer 3.1|1490320|32|NZ_CP017961|PILER-CR,CRT matches to MN693409 (Marine virus AFVG_25M351, complete genome) position: , mismatch: 6, identity: 0.812

tttcccgctaataggtttaccgtaaactaaat	CRISPR spacer
tttatctgtaataggtttaccgtaaagtaaag	Protospacer
*** .*  ****************** ****

14. spacer 1.1|192876|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NZ_CP032629 (Lactococcus sp. 1JSPR-7 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

atacatgctaatcaatttgataaggctgga	CRISPR spacer
atatatgctaatgaatttgataattatgct	Protospacer
***.******** **********   **

15. spacer 1.1|192876|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NC_019351 (Lactococcus lactis subsp. cremoris plasmid pAF22, complete sequence) position: , mismatch: 7, identity: 0.767

atacatgctaatcaatttgataaggctgga	CRISPR spacer
atatatgctaatgaatttgataattatgct	Protospacer
***.******** **********   **

16. spacer 1.7|193272|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NZ_CP027438 (Escherichia coli strain 2012C-4221 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

aatggctgtagtactttataccacctcagc	CRISPR spacer
aactgagcaagtactttataacacctcagc	Protospacer
**. *    *********** *********

17. spacer 1.9|192890|29|NZ_CP017961|PILER-CR matches to NZ_CP016173 (Bordetella flabilis strain AU10664 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

atacatgctaatcaatttgataaggctgg	CRISPR spacer
agagtgtgtaatcaatttgataagggtgg	Protospacer
* *     ***************** ***

18. spacer 1.10|192956|29|NZ_CP017961|PILER-CR matches to MN693535 (Marine virus AFVG_25M313, complete genome) position: , mismatch: 7, identity: 0.759

ggtagataaaagttaaattcattgagttt	CRISPR spacer
cattattaaaagtaaaattcattgggttt	Protospacer
 .* . ******* **********.****

19. spacer 1.14|193221|29|NZ_CP017961|PILER-CR matches to MK290739 (Pectobacterium phage Q19, complete genome) position: , mismatch: 7, identity: 0.759

aggtacggtctcctgctggtacatatcga	CRISPR spacer
acgtacggtctgctgctggaacatagttc	Protospacer
* ********* ******* ***** .

20. spacer 1.15|193287|29|NZ_CP017961|PILER-CR matches to AP019525 (Tenacibaculum phage PTm5 DNA, complete genome) position: , mismatch: 7, identity: 0.759

aatggctgtagtactttataccacctcag	CRISPR spacer
aatgtctgtagtactttataccattatgt	Protospacer
**** ******************.. ..

21. spacer 1.15|193287|29|NZ_CP017961|PILER-CR matches to AP019524 (Tenacibaculum phage PTm1 DNA, complete genome) position: , mismatch: 7, identity: 0.759

aatggctgtagtactttataccacctcag	CRISPR spacer
aatgtctgtagtactttataccattatgt	Protospacer
**** ******************.. ..

22. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to MF919502 (Mycobacterium phage Demsculpinboyz, complete genome) position: , mismatch: 7, identity: 0.759

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
ggaacggtaggcagttcgatgacctctcc	Protospacer
.*.* ******** ************

23. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to NC_009820 (Mycobacterium phage Tweety, complete genome) position: , mismatch: 7, identity: 0.759

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
ggaacggtaggcagttcgatgacctctcc	Protospacer
.*.* ******** ************

24. spacer 2.2|971771|32|NZ_CP017961|PILER-CR,CRISPRCasFinder,CRT matches to MG592553 (Vibrio phage 1.187.O._10N.286.49.F1, partial genome) position: , mismatch: 7, identity: 0.781

tattca---aaaagttaatctttatacttcttcaa	CRISPR spacer
---tcaggtaaaagttcatctttatactacttcgc	Protospacer
   ***   ******* *********** ****.

25. spacer 2.10|972252|32|NZ_CP017961|CRISPRCasFinder matches to KM606997 (Enterobacteria phage RB7, complete genome) position: , mismatch: 7, identity: 0.781

agtctgttattgattttctcaagcgttatttc	CRISPR spacer
actctcttattgatttgctcaagcgctctatt	Protospacer
* *** ********** ********.* * *.

26. spacer 2.10|972252|32|NZ_CP017961|CRISPRCasFinder matches to KM606998 (Enterobacteria phage RB9, complete genome) position: , mismatch: 7, identity: 0.781

agtctgttattgattttctcaagcgttatttc	CRISPR spacer
actctcttattgatttgctcaagcgctctatt	Protospacer
* *** ********** ********.* * *.

27. spacer 1.1|192876|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NZ_CP034149 (Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence) position: , mismatch: 8, identity: 0.733

atacatgctaatcaatttgataaggctgga	CRISPR spacer
tctgctgctaatcagtttgataatgctgaa	Protospacer
 .   *********.******** ****.*

28. spacer 1.1|192876|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NZ_CP016173 (Bordetella flabilis strain AU10664 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

atacatgctaatcaatttgataaggctgga	CRISPR spacer
agagtgtgtaatcaatttgataagggtggc	Protospacer
* *     ***************** ***

29. spacer 1.2|192942|30|NZ_CP017961|CRISPRCasFinder,CRT matches to MN693535 (Marine virus AFVG_25M313, complete genome) position: , mismatch: 8, identity: 0.733

ggtagataaaagttaaattcattgagttta	CRISPR spacer
cattattaaaagtaaaattcattgggtttg	Protospacer
 .* . ******* **********.****.

30. spacer 1.6|193206|30|NZ_CP017961|CRISPRCasFinder,CRT matches to MK290739 (Pectobacterium phage Q19, complete genome) position: , mismatch: 8, identity: 0.733

aggtacggtctcctgctggtacatatcgag	CRISPR spacer
acgtacggtctgctgctggaacatagttct	Protospacer
* ********* ******* ***** .

31. spacer 1.7|193272|30|NZ_CP017961|CRISPRCasFinder,CRT matches to AP019525 (Tenacibaculum phage PTm5 DNA, complete genome) position: , mismatch: 8, identity: 0.733

aatggctgtagtactttataccacctcagc	CRISPR spacer
aatgtctgtagtactttataccattatgtg	Protospacer
**** ******************.. ..

32. spacer 1.7|193272|30|NZ_CP017961|CRISPRCasFinder,CRT matches to AP019524 (Tenacibaculum phage PTm1 DNA, complete genome) position: , mismatch: 8, identity: 0.733

aatggctgtagtactttataccacctcagc	CRISPR spacer
aatgtctgtagtactttataccattatgtg	Protospacer
**** ******************.. ..

33. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NZ_CP040721 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
ccgaaggtaggagcttcgatgaccttcccg	Protospacer
  ********* .************.   *

34. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to MF919502 (Mycobacterium phage Demsculpinboyz, complete genome) position: , mismatch: 8, identity: 0.733

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
ggaacggtaggcagttcgatgacctctcca	Protospacer
.*.* ******** ************   .

35. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NC_009820 (Mycobacterium phage Tweety, complete genome) position: , mismatch: 8, identity: 0.733

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
ggaacggtaggcagttcgatgacctctcca	Protospacer
.*.* ******** ************   .

36. spacer 1.9|192890|29|NZ_CP017961|PILER-CR matches to NZ_CP034149 (Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence) position: , mismatch: 8, identity: 0.724

atacatgctaatcaatttgataaggctgg	CRISPR spacer
tctgctgctaatcagtttgataatgctga	Protospacer
 .   *********.******** ****.

37. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to NZ_CP040721 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
ccgaaggtaggagcttcgatgaccttccc	Protospacer
  ********* .************.

38. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to NC_005017 (Yersinia enterocolitica 8081 plasmid pYVe8081, complete sequence) position: , mismatch: 8, identity: 0.724

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
gccggggtaggcactacgatgacatcagc	Protospacer
.  ..********** ******* ****

39. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to NC_004564 (Yersinia enterocolitica plasmid pYVa127/90, complete sequence) position: , mismatch: 8, identity: 0.724

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
gccggggtaggcactacgatgacatcagc	Protospacer
.  ..********** ******* ****

40. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to NC_019234 (Yersinia enterocolitica (type O:8) plasmid pYV-WA314, complete sequence) position: , mismatch: 8, identity: 0.724

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
gccggggtaggcactacgatgacatcagc	Protospacer
.  ..********** ******* ****

41. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to NC_008791 (Yersinia enterocolitica subsp. enterocolitica 8081 plasmid pYVe8081, complete sequence) position: , mismatch: 8, identity: 0.724

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
gccggggtaggcactacgatgacatcagc	Protospacer
.  ..********** ******* ****

42. spacer 1.16|193353|29|NZ_CP017961|PILER-CR matches to NZ_CP009366 (Yersinia enterocolitica strain WA plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.724

aggaaggtaggcacttcgatgacctcaga	CRISPR spacer
gccggggtaggcactacgatgacatcagc	Protospacer
.  ..********** ******* ****

43. spacer 2.2|971771|32|NZ_CP017961|PILER-CR,CRISPRCasFinder,CRT matches to AJ630128 (Bacteriophage S-PM2 complete genome) position: , mismatch: 8, identity: 0.75

tattcaaaaagttaatctttatacttcttcaa	CRISPR spacer
cattcaaaaagttaatctttgtattttgactg	Protospacer
.*******************.**.**.  * .

44. spacer 2.2|971771|32|NZ_CP017961|PILER-CR,CRISPRCasFinder,CRT matches to NC_006820 (Synechococcus phage S-PM2, complete genome) position: , mismatch: 8, identity: 0.75

tattcaaaaagttaatctttatacttcttcaa	CRISPR spacer
cattcaaaaagttaatctttgtattttgactg	Protospacer
.*******************.**.**.  * .

45. spacer 2.2|971771|32|NZ_CP017961|PILER-CR,CRISPRCasFinder,CRT matches to LN828717 (Synechococcus phage S-PM2 spontaneous deletion mutant, complete genome) position: , mismatch: 8, identity: 0.75

tattcaaaaagttaatctttatacttcttcaa	CRISPR spacer
cattcaaaaagttaatctttgtattttgactg	Protospacer
.*******************.**.**.  * .

46. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NC_005017 (Yersinia enterocolitica 8081 plasmid pYVe8081, complete sequence) position: , mismatch: 9, identity: 0.7

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
gccggggtaggcactacgatgacatcagca	Protospacer
.  ..********** ******* **** .

47. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NC_004564 (Yersinia enterocolitica plasmid pYVa127/90, complete sequence) position: , mismatch: 9, identity: 0.7

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
gccggggtaggcactacgatgacatcagca	Protospacer
.  ..********** ******* **** .

48. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NC_019234 (Yersinia enterocolitica (type O:8) plasmid pYV-WA314, complete sequence) position: , mismatch: 9, identity: 0.7

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
gccggggtaggcactacgatgacatcagca	Protospacer
.  ..********** ******* **** .

49. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NC_008791 (Yersinia enterocolitica subsp. enterocolitica 8081 plasmid pYVe8081, complete sequence) position: , mismatch: 9, identity: 0.7

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
gccggggtaggcactacgatgacatcagca	Protospacer
.  ..********** ******* **** .

50. spacer 1.8|193338|30|NZ_CP017961|CRISPRCasFinder,CRT matches to NZ_CP009366 (Yersinia enterocolitica strain WA plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

aggaaggtaggcacttcgatgacctcagag	CRISPR spacer
gccggggtaggcactacgatgacatcagca	Protospacer
.  ..********** ******* **** .

51. spacer 2.2|971771|32|NZ_CP017961|PILER-CR,CRISPRCasFinder,CRT matches to MN693355 (Marine virus AFVG_25M40, complete genome) position: , mismatch: 9, identity: 0.719

tattcaaaaagttaatctttatacttcttcaa	CRISPR spacer
taaatctccagttaatctttttacttctttaa	Protospacer
**  .    *********** ********.**

52. spacer 2.2|971771|32|NZ_CP017961|PILER-CR,CRISPRCasFinder,CRT matches to CP052843 (Bacillus phage Hybphi3Ts, partial sequence) position: , mismatch: 9, identity: 0.719

tattcaaaaagttaatctttatacttcttcaa	CRISPR spacer
aaatcaaaaagttaatttttacactttaggta	Protospacer
 * *************.****.****.    *

53. spacer 2.10|972252|32|NZ_CP017961|CRISPRCasFinder matches to NZ_CP013139 (Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence) position: , mismatch: 9, identity: 0.719

agtctgttattgattttctcaagcgttatttc	CRISPR spacer
caaaagttattaatttgctcaagcgttaaatc	Protospacer
 .   ******.**** ***********  **

54. spacer 2.10|972252|32|NZ_CP017961|CRISPRCasFinder matches to NZ_CP044084 (Pseudomonas luteola strain FDAARGOS_637 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

agtctgttattgattttctcaagcgttatttc	CRISPR spacer
agcctgttattgatcttctcaagaccaaaccc	Protospacer
**.***********.********  . * ..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

68130 : 124309

Shigella_phage(29.03%)

plate,tRNA,head,tail,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005751773.1\|68130_70086_-\|tRNA	tRNA(Met) cytidine acetyltransferase	NA	NA	NA	NA
WP_005751774.1\|70104_70833_-	hypothetical protein	NA	NA	NA	NA
WP_005751775.1\|70950_71427_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_005751777.1\|71427_72546_-	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	1.2e-47	45.2
WP_005751778.1\|72739_73570_+	HAD-IIB family hydrolase	NA	NA	NA	NA
WP_005751779.1\|73627_75901_-	bifunctional glutamate--cysteine ligase/glutathione synthetase	NA	NA	NA	NA
WP_005751780.1\|76046_76955_-	DMT family transporter	NA	NA	NA	NA
WP_005751781.1\|76965_77979_-	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_005751782.1\|78085_78982_-	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_005751784.1\|79156_79624_+	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_005723197.1\|79674_80856_-	formate-dependent phosphoribosylglycinamide formyltransferase	NA	NA	NA	NA
WP_005717368.1\|80893_81400_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_005751786.1\|81573_82053_-	DedA family protein	NA	NA	NA	NA
WP_005717370.1\|82045_82657_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_005751787.1\|82662_83262_-	beta-phosphoglucomutase family hydrolase	NA	NA	NA	NA
WP_005733288.1\|83385_83766_+	PRD domain-containing protein	NA	NA	NA	NA
WP_005717374.1\|86402_86624_-	YceK/YidQ family lipoprotein	NA	NA	NA	NA
WP_071543600.1\|88846_90004_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_016534216.1\|90046_90568_+	MltR family transcriptional regulator	NA	NA	NA	NA
WP_005739261.1\|90684_91032_+	DUF3486 family protein	NA	NA	NA	NA
WP_005752524.1\|91163_91709_-	DNA-binding protein	Q38013	Pseudomonas_phage	4.5e-05	41.7
WP_005752523.1\|91906_92122_+	DNA-binding protein	A0A2I7S995	Vibrio_phage	7.2e-15	60.6
WP_005752521.1\|92141_94133_+\|transposase	transposase	C9DGL1	Escherichia_phage	3.0e-147	44.3
WP_005752519.1\|94351_94828_-	hypothetical protein	NA	NA	NA	NA
WP_005752517.1\|95783_96101_+	hypothetical protein	A0A0M3LQH1	Mannheimia_phage	2.0e-13	45.2
WP_005752515.1\|96125_96650_+	host-nuclease inhibitor protein Gam	F6MIJ0	Haemophilus_phage	1.2e-82	93.0
WP_005752514.1\|96649_96844_+	hypothetical protein	NA	NA	NA	NA
WP_005752513.1\|96912_97131_+	ANR family transcriptional regulator	NA	NA	NA	NA
WP_005752512.1\|97130_97316_+	hypothetical protein	F6MIJ2	Haemophilus_phage	6.4e-20	96.4
WP_005752510.1\|97526_98075_+	DUF1018 domain-containing protein	NA	NA	NA	NA
WP_005752508.1\|98061_98616_+	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	9.2e-46	54.1
WP_071543601.1\|98819_99248_+	transcriptional regulator	A0A0C4UQZ9	Shigella_phage	2.5e-22	43.9
WP_005752505.1\|99330_99876_+	N-acetylmuramoyl-L-alanine amidase	F6MIJ9	Haemophilus_phage	9.6e-80	75.4
WP_005752503.1\|99878_100097_+	DUF2644 domain-containing protein	F6MIK0	Haemophilus_phage	9.2e-26	88.4
WP_005738312.1\|100099_100372_+	DUF2681 domain-containing protein	NA	NA	NA	NA
WP_005738314.1\|100500_100728_+	hypothetical protein	NA	NA	NA	NA
WP_005752500.1\|100724_101054_+	DUF2730 family protein	NA	NA	NA	NA
WP_005752497.1\|101050_101344_+	hypothetical protein	A0A2I7S9D8	Vibrio_phage	1.4e-24	65.6
WP_005752496.1\|101377_101947_+	DUF3486 family protein	A0A2I7S9D1	Vibrio_phage	6.5e-39	45.4
WP_100248327.1\|101943_103467_+	hypothetical protein	A0A2I7S9C5	Vibrio_phage	2.1e-161	61.8
WP_021734325.1\|103469_105029_+	DUF935 domain-containing protein	A0A0C4UQR8	Shigella_phage	7.6e-146	52.8
WP_100248329.1\|105102_106347_+\|head	phage head morphogenesis protein	C9DGN7	Escherichia_phage	2.5e-83	40.6
WP_005752491.1\|106491_106926_+	phage virion morphogenesis protein	NA	NA	NA	NA
WP_005752489.1\|107155_108220_+	hypothetical protein	A0A0C4UQU6	Shigella_phage	1.3e-72	48.9
WP_005752488.1\|108219_109143_+\|head	head protein	A0A0C4UQR9	Shigella_phage	3.4e-93	55.4
WP_005752486.1\|109215_109635_+	hypothetical protein	NA	NA	NA	NA
WP_100248326.1\|109631_110054_+	DUF1320 domain-containing protein	NA	NA	NA	NA
WP_005738156.1\|110615_110807_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_005752482.1\|110806_112270_+\|tail	tail protein	A0A0C4UQS0	Shigella_phage	2.0e-124	50.2
WP_005752480.1\|112280_112634_+\|tail	tail protein	A0A2P1A4D6	Alteromonadaceae_phage	1.7e-08	32.7
WP_005752478.1\|112636_113020_+	hypothetical protein	C9DGP9	Escherichia_phage	2.7e-20	51.3
WP_005752477.1\|113109_115011_+	tape measure domain-containing protein	A0A2I7S9D9	Vibrio_phage	1.7e-51	33.6
WP_005752475.1\|115020_116385_+	DNA circularization protein	A0A0C4UR32	Shigella_phage	8.1e-35	27.9
WP_016534010.1\|117155_117635_+\|tail	tail protein gpP	M4M9L5	Vibrio_phage	1.4e-13	38.1
WP_005737833.1\|117666_118215_+\|plate	phage baseplate assembly protein V	A0A0C4UQZ3	Shigella_phage	1.7e-31	40.7
WP_005752473.1\|118225_118636_+	hypothetical protein	A0A0C4UR04	Shigella_phage	3.5e-18	38.7
WP_005752471.1\|118635_119703_+\|plate	baseplate J/gp47 family protein	A0A0C4UQU9	Shigella_phage	1.2e-70	43.1
WP_100248328.1\|119735_120293_+	YmfQ family protein	A0A2I7S9L6	Vibrio_phage	4.2e-22	34.6
WP_005752467.1\|120295_122515_+	hypothetical protein	A0A1Y0SVL0	Pasteurella_phage	5.1e-87	33.1
WP_005752465.1\|122517_123066_+	hypothetical protein	NA	NA	NA	NA
WP_005752464.1\|123044_123329_+	hypothetical protein	A0A0M3LNN9	Mannheimia_phage	1.4e-21	64.9
WP_030017229.1\|124051_124309_-	hypothetical protein	F6MIM3	Haemophilus_phage	3.5e-40	98.8

DBSCAN-SWA_2

273171 : 334412

uncultured_Caudovirales_phage(35.29%)

tRNA,head,terminase,integrase,portal,tail,capsid,protease

attL 297814:297829|attR 324669:324684

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005723679.1\|273171_275754_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	5.9e-188	41.9
WP_005751897.1\|275809_276313_+	hypothetical protein	NA	NA	NA	NA
WP_005751898.1\|276312_277392_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_005717609.1\|277520_277787_+	DUF5339 domain-containing protein	NA	NA	NA	NA
WP_005751899.1\|277852_278254_-	8-oxo-dGTP diphosphatase MutT	NA	NA	NA	NA
WP_005751900.1\|278346_281034_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_005723689.1\|281117_281429_-	DUF2547 family protein	NA	NA	NA	NA
WP_005723691.1\|281521_281827_+	DUF721 domain-containing protein	NA	NA	NA	NA
WP_005723696.1\|281873_282779_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S6L1V5	Vibrio_phage	1.8e-62	48.9
WP_005751902.1\|282782_283871_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_005717623.1\|283887_284415_-	shikimate kinase AroK	NA	NA	NA	NA
WP_016533996.1\|284597_285932_-	type IV pilus secretin PilQ	NA	NA	NA	NA
WP_005748555.1\|285941_286304_-	hypothetical protein	NA	NA	NA	NA
WP_005751903.1\|286306_286831_-	hypothetical protein	NA	NA	NA	NA
WP_005751904.1\|286830_287346_-	hypothetical protein	NA	NA	NA	NA
WP_005734313.1\|287385_288159_-	competence protein ComA	NA	NA	NA	NA
WP_005751906.1\|290886_292299_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_005751907.1\|292409_293297_+	pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA	NA	NA	NA
WP_005723715.1\|293299_293881_+	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA	NA	NA	NA
WP_005723717.1\|294041_294887_+	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_005748588.1\|294983_296339_+	glutathione-disulfide reductase	NA	NA	NA	NA
WP_017351019.1\|296426_297005_-	thymidine kinase	A0A1Z1LZ42	Serratia_phage	1.8e-52	52.1
WP_005734335.1\|297006_297243_-	hypothetical protein	NA	NA	NA	NA
WP_005751909.1\|297263_298295_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.3e-111	58.3
297814:297829	attL	NA	NA	NA	NA
WP_005717672.1\|298513_298729_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_005751910.1\|298844_300593_+	DNA primase	A0A1S5RF71	Helicobacter_phage	1.1e-41	32.6
WP_005751911.1\|300668_302537_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	4.5e-36	33.8
WP_021734338.1\|302632_304639_-	transketolase	NA	NA	NA	NA
WP_005752180.1\|304666_305617_-	transaldolase	A0A127KNC6	Cyanophage	6.3e-10	26.5
WP_016534207.1\|305634_306684_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_005718518.1\|306696_307368_-	cyclase family protein	NA	NA	NA	NA
WP_005718519.1\|308670_309147_-	TRAP transporter small permease	NA	NA	NA	NA
WP_005718520.1\|309200_310178_-	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_005718521.1\|310226_310682_-	ribose 5-phosphate isomerase B	NA	NA	NA	NA
WP_005752183.1\|311648_312509_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_014668511.1\|312687_313314_-	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_005718532.1\|313315_314320_-	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_005718533.1\|314340_315354_-	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_016534272.1\|315706_316696_+	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_016534271.1\|316719_317280_+	TRAP transporter small permease	NA	NA	NA	NA
WP_005752188.1\|317276_318557_+	TRAP transporter large permease	NA	NA	NA	NA
WP_017350204.1\|319130_320330_+\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	1.7e-84	40.6
WP_005752837.1\|320505_322110_-	DNA primase	Q7M2A8	Enterobacteria_phage	2.4e-70	38.0
WP_016534279.1\|322093_322519_-	hypothetical protein	NA	NA	NA	NA
WP_016534278.1\|322837_323053_-	hypothetical protein	NA	NA	NA	NA
WP_005752851.1\|323045_323264_-	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_005752847.1\|323749_323953_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_005752845.1\|324106_324700_-	hypothetical protein	NA	NA	NA	NA
324669:324684	attR	NA	NA	NA	NA
WP_016534138.1\|324902_325367_-	hypothetical protein	NA	NA	NA	NA
WP_016534137.1\|325378_327046_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	5.8e-245	70.3
WP_005737917.1\|327045_327414_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	3.3e-36	63.4
WP_016534136.1\|327588_330318_-	tape measure protein	A0A0M3LS69	Mannheimia_phage	1.1e-179	39.1
WP_005737945.1\|330375_330732_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	1.2e-27	50.9
WP_005737947.1\|330740_331067_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_005753109.1\|331053_331401_-\|head	phage head closure protein	A0A286S2A2	Klebsiella_phage	5.6e-09	39.1
WP_016534135.1\|331393_332605_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	1.6e-143	62.0
WP_005752727.1\|332606_333161_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	5.4e-54	61.0
WP_005752729.1\|333212_334412_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	2.5e-128	61.9

DBSCAN-SWA_3

1399818 : 1409178

Planktothrix_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005721071.1\|1399818_1400817_+	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.3e-15	29.4
WP_005751181.1\|1400833_1401814_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.0e-15	30.9
WP_005724066.1\|1401892_1402678_-	zinc ABC transporter permease subunit ZnuB	NA	NA	NA	NA
WP_005728339.1\|1402686_1403478_-	zinc ABC transporter ATP-binding protein ZnuC	W6JKT0	Anomala_cuprea_entomopoxvirus	3.4e-17	29.7
WP_005751182.1\|1403712_1405266_+	murein DD-endopeptidase MepM	A0A2K9VGT1	Pontimonas_phage	1.9e-19	49.6
WP_005751184.1\|1405341_1406289_-	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	3.3e-43	38.4
WP_005724298.1\|1406358_1407246_-	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_005751185.1\|1407245_1407863_-	lipoprotein localization protein LolB	NA	NA	NA	NA
WP_005751186.1\|1407903_1409178_-	multifunctional CCA addition/repair protein	A0A0F6YPT7	Sinorhizobium_phage	8.8e-92	49.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP017961

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection