CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	1 crisprs	DEDDh,csf2gr7,DinG,cas6e,RT,c2c9_V-U4,Cas14b_CAS-V-F	0	6	0	0
NZ_CP018027	Alteromonas mediterranea strain CP49 chromosome, complete genome	1 crisprs	cas1,cas3f,cas7f,cas5,cas6f,cas3,DEDDh,WYL,Cas9_archaeal,csa3,DinG	0	7	1	0

1. NZ_CP018028

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018028_1

• CRISPR_ID: NZ_CP018028_1
• CRISPR_location: 187598-187994
• CRISPR_type: TypeIV-A
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: csf2gr7,DinG,cas6e

Consensus repeat of NZ_CP018028_1

Consensus_repeat	Method
CGGTTCACCCCCACCTACGCGGGGAATAC	CRISPRCasFinder
CGGTTCACCCCCACCTACGCGGGGAATAC	PILER-CR

spacers of NZ_CP018028_1

>1.1|187627|33|NZ_CP018028|CRISPRCasFinder
TCACATGGCCATATTGCTCGATACTCGATGTTG
>1.2|187689|33|NZ_CP018028|CRISPRCasFinder
ACCTGTTAGTGAGTCAACATTATCAGGTTTTCA
>1.3|187751|32|NZ_CP018028|CRISPRCasFinder,PILER-CR
AAAGAGCCAATGCCTTCTTCGCACTTTATTGA
>1.4|187812|32|NZ_CP018028|CRISPRCasFinder,PILER-CR
GGTTGGTCTTTGACCAGTCCCTAAGCCCTTGG
>1.5|187873|32|NZ_CP018028|CRISPRCasFinder,PILER-CR
TTCTCTGCGGCCGCACACAATAAGTCCATTAC
>1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR
CTACTGCTTTAAAAAAAGACTCATCATCAAGT

CRISPR arrays and Neighbor proteins around NZ_CP018028_1

CRISPR arrays

The CRISPR arrays of NZ_CP018028_1

>merge|NZ_CP018028|1|187598-187994|CRISPRCasFinder,PILER-CR
CAGATTATCCCCGCCTACGCGGGGAATACTCACATGGCCATATTGCTCGATACTCGATGTTGCGGTTCACCCCCGACTACACGGGGTATACACCTGTTAGTGAGTCAACATTATCAGGTTTTCACGGTTCACCCCCACCTGCGCGGGGAATACAAAGAGCCAATGCCTTCTTCGCACTTTATTGACGGTTCACCCCCACCTACGCGGGGAATACGGTTGGTCTTTGACCAGTCCCTAAGCCCTTGGCGGTTCACCCCCGCCTACGCGGGGAATACTTCTCTGCGGCCGCACACAATAAGTCCATTACCGGTTCACCCCCACCTACGCGGGGAATACCTACTGCTTTAAAAAAAGACTCATCATCAAGTCGGTTCACCCCCGCCTACGCGGGGAATAC

>NZ_CP018028|1|1|187598-187994|CRISPRCasFinder
CAGATTATCCCCGCCTACGCGGGGAATAC	TCACATGGCCATATTGCTCGATACTCGATGTTG
CGGTTCACCCCCGACTACACGGGGTATAC	ACCTGTTAGTGAGTCAACATTATCAGGTTTTCA
CGGTTCACCCCCACCTGCGCGGGGAATAC	AAAGAGCCAATGCCTTCTTCGCACTTTATTGA
CGGTTCACCCCCACCTACGCGGGGAATAC	GGTTGGTCTTTGACCAGTCCCTAAGCCCTTGG
CGGTTCACCCCCGCCTACGCGGGGAATAC	TTCTCTGCGGCCGCACACAATAAGTCCATTAC
CGGTTCACCCCCACCTACGCGGGGAATAC	CTACTGCTTTAAAAAAAGACTCATCATCAAGT
CGGTTCACCCCCGCCTACGCGGGGAATAC

>NZ_CP018028|1|1|187722-187994|PILER-CR
CGGTTCACCCCCACCTGCGCGGGGAATAC	AAAGAGCCAATGCCTTCTTCGCACTTTATTGA
CGGTTCACCCCCACCTACGCGGGGAATAC	GGTTGGTCTTTGACCAGTCCCTAAGCCCTTGG
CGGTTCACCCCCGCCTACGCGGGGAATAC	TTCTCTGCGGCCGCACACAATAAGTCCATTAC
CGGTTCACCCCCACCTACGCGGGGAATAC	CTACTGCTTTAAAAAAAGACTCATCATCAAGT
CGGTTCACCCCCGCCTACGCGGGGAATAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018028.1|WP_071960741.1|196449_196797_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960725.1|184419_185115_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960729.1|186378_187374_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960730.1|188053_189157_-|hypothetical-protein	csf2gr7	mkCas0162_csf2gr7_CAS-IV-A	gnl|CDD|187814
NZ_CP018028.1|WP_071960720.1|180252_180684_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960722.1|181398_182457_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960721.1|180791_181361_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960736.1|194662_194848_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960723.1|182529_182961_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_155761682.1|195143_195383_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960732.1|189898_191893_-|hypothetical-protein	DinG	COG1199_DinG_CAS-IV-A	gnl|CDD|224120
NZ_CP018028.1|WP_071960740.1|195636_196368_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960734.1|192480_193449_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960731.1|189176_189902_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960724.1|183304_184354_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960727.1|185502_185796_+|hypothetical-protein	unknown	unknown	gnl|CDD|373524
NZ_CP018028.1|WP_071960735.1|193714_194467_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_071960733.1|191885_192479_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|215025
NZ_CP018028.1|WP_071960726.1|185126_185384_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018028.1|WP_155761718.1|186018_186378_+|ATP-binding-protein	unknown	unknown	gnl|CDD|378817

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP018028.1|WP_071960733.1|191885_192479_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	2.9e-16	54.9	0.1
NZ_CP018028.1|WP_071960732.1|189898_191893_-|hypothetical-protein	DinG	COG1199_DinG_CAS-IV-A	1.2e-36	120.9	0.0
NZ_CP018028.1|WP_071960730.1|188053_189157_-|hypothetical-protein	csf2gr7	mkCas0162_csf2gr7_CAS-IV-A	2e-18	61.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP018028.1|WP_071960732.1|189898_191893_-|hypothetical-protein	gnl|CDD|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	8.76643e-38
NZ_CP018028.1|WP_071960733.1|191885_192479_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|215025	smart01101, CRISPR_assoc, This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.75474e-13
NZ_CP018028.1|WP_071960727.1|185502_185796_+|hypothetical-protein	gnl|CDD|373524	pfam15065, NCU-G1, Lysosomal transcription factor, NCU-G1. NCU-G1 is a set of highly conserved nuclear proteins rich in proline with a molecular weight of approximately 44 kDa. Especially high levels are detected in human prostate, liver and kidney. NCU-G1 is a dual-function family capable of functioning as a transcription factor as well as a nuclear receptor co-activator by stimulating the transcriptional activity of peroxisome proliferator-activated receptor-alpha (PPAR-alpha).	0.00175355
NZ_CP018028.1|WP_155761718.1|186018_186378_+|ATP-binding-protein	gnl|CDD|378817	pfam12128, DUF3584, Protein of unknown function (DUF3584). This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.	1.07277e-10
NZ_CP018028.1|WP_071960730.1|188053_189157_-|hypothetical-protein	gnl|CDD|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	0.00247109

Protein sequences

>NZ_CP018028.1|WP_071960729.1|186378_187374_-|hypothetical-protein
MQSHPSYTAGSTIPVNIEYVSPDEQNVLRVLPKGAWLARNTSDGTVTLSPDANAVSKGEAHPVMSGVTHVMQGPVARVFPGLTTENMHNFADIFKYKVDQIVFPQRYGSTSVEVEQENNALKTVLSDIGATFVASGRGVFPFDPESEAFLEPIQPKSDLLIGYPVNAQRIIATEPPLDNFKVMLINIGIPKNTVDGITSDKGMLPFKVTREDLGALPDELHQDLAHKIRYKAVHATGHMTLGGLTAKSTDELNAEILADALDETLMYASETTIPFYLESALVSLGAPYSEALRSDVNALSYYDNKDFYNSVYTTLKAHTSDDPVPDLGIKY
>NZ_CP018028.1|WP_155761718.1|186018_186378_+|ATP-binding-protein
MYHHHSIFPSVLTKLPCYTHSNLVGGNGAGKTTMLSLIPIFYGVETNQMVSTDSDGASLEIHSKKSAYGAQLAILTKLIDSRDLAIKKVADVTRESRIAIMQERMLAFRLPLTCVRIGC
>NZ_CP018028.1|WP_071960727.1|185502_185796_+|hypothetical-protein
MDKDQYHGYKKIFMGQGMNDKASMRMVANSMGMMGTPLMVMGVILVIVGIPLIALMGAGIFLIISGLVAFFFGRKQKKKKISFLEMIEADEDLPERA
>NZ_CP018028.1|WP_071960726.1|185126_185384_+|hypothetical-protein
MSLPSVHEVEVCPKCGSQNGFYIRSRVSGLVQINYSFDGSGSDNQDMYTPLKHNDQKFAYCQQCESKIGRWDEKAKSIVSTRVRF
>NZ_CP018028.1|WP_071960725.1|184419_185115_+|hypothetical-protein
MAKKAVKVNESENIKRASRVFPNINFKTLGKAVETLFTTSSAQKNHDCIGVAVLVIALLKRRGIDAELCVGEVAWRVDGQASGGVISHVSQQPGVSTVITPESLDPNMDAFPFHAWIKLNEIWYCDFSTYQFQSKMDVLNQDGQNVPVTWKPPFLMFTKSDVSGYLDVANSFSAKVIYYSERQALLDKVNQKSPTADNDDLAALELIYNQIENGELDTVIGPYGNVTLKKD
>NZ_CP018028.1|WP_071960724.1|183304_184354_+|hypothetical-protein
MNTQHQFYLPKNDDELNAYVSSINTAYGDGFDFKVGEKRSEKLRDVICKHLGFTNGYQQLQAHWRKGVNDLLTGDDSTACLIYADAFGPLPVAMVASPVAKILTEKLNELFPCSKKGFYRDDEGEGSQGWGYGVVPSTHALSEYEKCSWVPLYMGSLLIGYTRADMSRHRPILIQGLISGAWLSEKSMLDNLREFFSSPRGKKWGCLIDNSVTPPALSFGKVLSLRMSSMETSVIIPLQGDVEISSDAMSFQTYYAQPTGISVLKNFHVDADRHGTLFVNGIGFDFASIYDFNPKGDGFVVKNAQSNSAYFESEKTSSVEWFGVEGVEIRKDDNVELHNFSDGDLVVLV
>NZ_CP018028.1|WP_071960723.1|182529_182961_-|hypothetical-protein
MNNIHHMQYVKTPSGSIMPTGKCLSEWLEQHPTLIPGDKIAMQDGQLFAYVVEKLTDFDQVNTEVFCKEILQHKELLVLMRREHGKVMFEQFIYAERRVITPEGLFSKQVLVTSFGDPAWVNVSDHAVIVRRDDYEEDKAKYH
>NZ_CP018028.1|WP_071960722.1|181398_182457_-|hypothetical-protein
MPFSYPSGPPMAEKSISRERALHMAHFPQDYVDAHEAGKISIPSGQAGQAWRNFFNNPEKYQRNLTAFGLGGVLAFKGEGMTGYYGGTKIPFHRVASNSVKPDTIAVKEKVASLANAAKEAAINAKLAWKASIPRHGGIHFGSTHEKLHDKYKELQRKADRFDDNGRVTKWVDFEVFCKKHEKFSDPHFLDYAYFKEAYPVHLAHTSQNDFTYVMSNKTSTSDSLEKLRESAEFMFGAAPESLEGSVVSRDGNAFIISNPVVIRNDAGLPLLAYGMNEKESGSLSSDIILQDPSGNGFGLATMDNINDVHLDYPTFDRMKNELQVSNMPEIIAVGENDLSKDVEVTPLRLGR
>NZ_CP018028.1|WP_071960721.1|180791_181361_+|hypothetical-protein
MNWKKSVAIKQFFRAGASEDEACIIGKQIAEHLTGSLKSYLASCGDDADNMHDAIENLKSVNSVSMWEELTAEDPTWCDMPPLKELDERLNDFYDEADRLAIWVDPNAPEFESFELNSVGTIKVGTPLYIKGKNVGRDSYERVLVKDVVNAGKENEEVIINSDSNYYFLTKSYLENKSWAARIDILGHP
>NZ_CP018028.1|WP_071960720.1|180252_180684_+|hypothetical-protein
MTLSLAEQVNKLERKAQNFDDAVDRIMELKIWVDDFENGDTSPHAVINKVKSLIKFYESSSREWLAKIEEQGYQQGGLVKYTNSTFNGKKIIEVKAMKDGEVFAVTDTGLHTIGFTSDGLSYKQGLDSIICDLQDVEGLKLSK
>NZ_CP018028.1|WP_071960730.1|188053_189157_-|hypothetical-protein
MSFFAENKRFSFNITGEVTAQSPISVSRPDDNFVSATGTKDKPRLPRAGAKKDATLPFIPGSSFRGGLRRAARDVIRRLTGEQFDIATSYMLTQGVDITNTMNSQKSAGNIGLEEPLRTLNPLLSLFGAWSLPGHTGVSDLIPTTPGSVFTAGGGVRTNDFIRDPKQIQFLSPEDAEKLQQIILDDSATASEVGELKKEISDLKAKMRDSRDKEVKASIQEEINHIDAMIKVKKESKSGATETIQRPLEGYEAIVPGTVMQHRLPLTMVNAMEMALFLESLATYAKNPVIGGHKNHACGFFSATYAIRHWPEDEDVSREVASIRFNETGFFIEGEIADELQSIRKTFRTAVSDGKFNFKAFLFKHAV
>NZ_CP018028.1|WP_071960731.1|189176_189902_-|hypothetical-protein
MTPFLLQARLITPCVYNRPIRLPGLLYHALLSHYCDEDKAQSALPTLLKENDGVFHGSSLIFGIQPESPVIACFQPSLGIMRNESDFNRSLISPNGRGGKYVSVQLDGGATKTRLGNNQAYHAPFVTFFGYGHSDKITALLNHYVSAVGINATRGAGTLAPNSWDAREISEDHSLIDITGKTGEANRGMPLTPLPEELFKALSPKKYGDHESEMVALRPPYYKNTELKLCAVPEKVSRQLI
>NZ_CP018028.1|WP_071960732.1|189898_191893_-|hypothetical-protein
MSKLKELTSHVFSPDGWLIENGYRHTDVQLAYALSVCDAIEHSKQIHAISADTGVGKTLAYLVVSALYNALNNKRVVIATHSIELLRQIEKDIPIANRITEALTDTTVPFSTRIGKQHYLDPDRIELLYVNLVDEGVELTSKHHELLSWAKTSALTGSGLISDWRQSFGALPIGVTEEAICLTKYSRDGANNAESRSSANAKVAGIVITTHAMMINAAFTEVLGNIGDITFLIDEGDKFENAAELIGNVFIPVKRIASIAKACLSNLKSKKSKSLSALINLAYEYDNALRDMDTGKDIHFKHVGNEQIKQVEHCVSEIVQSMSVALKSSKRSLANLTAFNELQLINDFLSSFNKNISLRGLHFSKKRRNPAFLRFFQSPAAVIHRHLEKGASAIFTSATIRDMGRSEISFSFLASTLMVAESDMGVKASFSPRQYGDLQFFVPDNELPNPYQHGEVNSLWRRYVTDVIRYTQSRYERVLVLATSFDEVDALSILLKGHGAFHKQGTGLAPLVAQWEKNGGILVSPSVWEGFSPRLSDGSQMFSSLVITKLPYSVPCELKLGELRGRLASQGSHYSAEAIYYKNLTQVAMRRFCQGIGRAVRAETDQCDIYICDPRILGNIKLKQGFAKALPKRFEVKLEDACQFDGKVSIEKAAKTMDELEGWV
>NZ_CP018028.1|WP_071960733.1|191885_192479_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MLCVYQESHFLMPNTGQHNANNWHKAIMDVLTNGHHIESLQYLFKTDISPRMPESSLVRVRGLSLPEHCQPVERKQNFTKGVQAAFRLRLCTTRRKKTTVNGKEKTIETFVSEKNDAFHGFLSQKLSSNGFALDSITEIQDTVVERVKRGGTQFFSPRCDVTFLATITDEEAAAIAYVKGIGRNKVFGAGMMEALDV
>NZ_CP018028.1|WP_071960734.1|192480_193449_-|hypothetical-protein
MNGTDFIFETLPDLYEGIETRPSTPSDFCACCQRHVKDTAVPDKSWEGKIYSKTEVHCIPCQVLYHPNQKHFGVEGYRSRQVRYADKETALKANQAITRMGDVKVKDRVTSLSKEGFTLFPTEEDAMAALGEAHEVVVNAGSAVIGKLGMLVGAGMAISANKAIFYAPGKHFDKLTGVGELFIKKQIGGYAMITDVINEFDGSEPFLFIGDFGKKKAELVSNLTLSKGKRSFISCSANGAMRINRNAYLALRQYVLAHFSSAPKSTTADFFKTLRSLASGYTPVSVAQDKLKDLPRIGELLKTLPTCPHERIELTIAVDKGL
>NZ_CP018028.1|WP_071960735.1|193714_194467_+|hypothetical-protein
MFKRIVLTALLVVSSGASKAALVEWHPTFDTTGTSDVVTLGETVEAFNFSSDGTLYEEPRSQDAEINGITFLELTDTFDLDAGERSFLETDVTGATSGDVDYDMLLDTLDYGGGKDSVSFYAGDGYLVEGNAYLVQFWYADIREDLTGSRIMRVGDGNASDALLHNYGEGLGQYIIGTFVADSDSQYFEFQVETNFGNAHLNAYQLRDVTGESTFNLAEGRNLAEVPAPLLPSLACFILMLIRRGKRSLV
>NZ_CP018028.1|WP_071960736.1|194662_194848_+|hypothetical-protein
MNNEQKEYVEKGGENCYKCGSSMIEGGEVSISPGRASQDVWCTECDHEWTTEYTLTSVSES
>NZ_CP018028.1|WP_155761682.1|195143_195383_+|hypothetical-protein
MQEYIEFETNDGIRKVALDRLVLKVSSCSQQGASYHALTMGALESNPQNATLLAPISKLRFDELRGKHPSLPLLRREMD
>NZ_CP018028.1|WP_071960740.1|195636_196368_+|hypothetical-protein
MDCNEKKSQIAFLTEKALDISLNEKELAALIEQTAATINEGGIELFKAFKQNFKDFRPLSIQQLFDGTASPQDERKEVLFSSVLQKITVPPEKSKAHDLPKSLYRGCSLNPLQLRRQNGYCRLDGERSLYKHQMATGRSIYISATSKLSIACEFAMQSERRGGGGHWVYQINPINASSCNDHLSPLRFHAGESEYVFTKHLPFEQIESVAWARNCDELETDFYSIDDAHYLLRELVIKGIAKI
>NZ_CP018028.1|WP_071960741.1|196449_196797_+|hypothetical-protein
MTSYKSFLLFFFAMVLAVLSQLLPVNHDDMHFALKMSFVPCCCAVVLSYLFKMDVNNKESWRREVFIFCASVLGSVLLIKLSVSGIGILSMLFGIAITVLLLTLLLNVVEGATAR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018028_1	1.1|187627|33|NZ_CP018028|CRISPRCasFinder	187627-187659	33	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	187627-187659	0	1.0
NZ_CP018028_1	1.1|187627|33|NZ_CP018028|CRISPRCasFinder	187627-187659	33	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	187669-187701	0	1.0
NZ_CP018028_1	1.2|187689|33|NZ_CP018028|CRISPRCasFinder	187689-187721	33	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	187689-187721	0	1.0
NZ_CP018028_1	1.2|187689|33|NZ_CP018028|CRISPRCasFinder	187689-187721	33	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	187731-187763	0	1.0
NZ_CP018028_1	1.3|187751|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187751-187782	32	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	187751-187782	0	1.0
NZ_CP018028_1	1.3|187751|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187751-187782	32	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	187793-187824	0	1.0
NZ_CP018028_1	1.4|187812|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187812-187843	32	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	187812-187843	0	1.0
NZ_CP018028_1	1.4|187812|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187812-187843	32	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	187854-187885	0	1.0
NZ_CP018028_1	1.5|187873|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187873-187904	32	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	187873-187904	0	1.0
NZ_CP018028_1	1.5|187873|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187873-187904	32	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	187915-187946	0	1.0
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	187934-187965	0	1.0
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	187976-188007	0	1.0
NZ_CP018028_1	1.3|187751|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187751-187782	32	NZ_CP012203	Alteromonas macleodii strain HOT1A3 plasmid pAM1A3, complete sequence	129062-129093	3	0.906
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_KX869741	Enterobacter cloacae strain 20130723 plasmid R222, complete sequence	129956-129987	6	0.812
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_CP027678	Salmonella enterica subsp. enterica serovar Corvallis strain 12-01738 plasmid pSE12-01738-1, complete sequence	18798-18829	6	0.812
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_LT994833	Klebsiella pneumoniae isolate CNR341 plasmid CNR341, complete sequence	59063-59094	6	0.812
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_CP043927	Klebsiella quasipneumoniae subsp. quasipneumoniae strain M17277 plasmid p17277A_477, complete sequence	270453-270484	6	0.812
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_LT882699	Enterobacter cloacae isolate Enterobacter cloacae ENCL58 plasmid I, complete sequence	82658-82689	6	0.812
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	NZ_CP013139	Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence	788659-788690	6	0.812
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	MT647605	Pelagibacter phage Lederberg EXVC029P, complete genome	8982-9013	8	0.75
NZ_CP018028_1	1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR	187934-187965	32	JQ340088	Halocynthia phage JM-2012, complete genome	119835-119866	8	0.75

1. spacer 1.1|187627|33|NZ_CP018028|CRISPRCasFinder matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 0, identity: 1.0

tcacatggccatattgctcgatactcgatgttg	CRISPR spacer
tcacatggccatattgctcgatactcgatgttg	Protospacer
*********************************

2. spacer 1.1|187627|33|NZ_CP018028|CRISPRCasFinder matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 0, identity: 1.0

tcacatggccatattgctcgatactcgatgttg	CRISPR spacer
tcacatggccatattgctcgatactcgatgttg	Protospacer
*********************************

3. spacer 1.2|187689|33|NZ_CP018028|CRISPRCasFinder matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 0, identity: 1.0

acctgttagtgagtcaacattatcaggttttca	CRISPR spacer
acctgttagtgagtcaacattatcaggttttca	Protospacer
*********************************

4. spacer 1.2|187689|33|NZ_CP018028|CRISPRCasFinder matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 0, identity: 1.0

acctgttagtgagtcaacattatcaggttttca	CRISPR spacer
acctgttagtgagtcaacattatcaggttttca	Protospacer
*********************************

5. spacer 1.3|187751|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 0, identity: 1.0

aaagagccaatgccttcttcgcactttattga	CRISPR spacer
aaagagccaatgccttcttcgcactttattga	Protospacer
********************************

6. spacer 1.3|187751|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 0, identity: 1.0

aaagagccaatgccttcttcgcactttattga	CRISPR spacer
aaagagccaatgccttcttcgcactttattga	Protospacer
********************************

7. spacer 1.4|187812|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 0, identity: 1.0

ggttggtctttgaccagtccctaagcccttgg	CRISPR spacer
ggttggtctttgaccagtccctaagcccttgg	Protospacer
********************************

8. spacer 1.4|187812|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 0, identity: 1.0

ggttggtctttgaccagtccctaagcccttgg	CRISPR spacer
ggttggtctttgaccagtccctaagcccttgg	Protospacer
********************************

9. spacer 1.5|187873|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 0, identity: 1.0

ttctctgcggccgcacacaataagtccattac	CRISPR spacer
ttctctgcggccgcacacaataagtccattac	Protospacer
********************************

10. spacer 1.5|187873|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 0, identity: 1.0

ttctctgcggccgcacacaataagtccattac	CRISPR spacer
ttctctgcggccgcacacaataagtccattac	Protospacer
********************************

11. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 0, identity: 1.0

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
ctactgctttaaaaaaagactcatcatcaagt	Protospacer
********************************

12. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 0, identity: 1.0

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
ctactgctttaaaaaaagactcatcatcaagt	Protospacer
********************************

13. spacer 1.3|187751|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP012203 (Alteromonas macleodii strain HOT1A3 plasmid pAM1A3, complete sequence) position: , mismatch: 3, identity: 0.906

aaagagccaatgccttcttcgcactttattga	CRISPR spacer
aaagagccaatgccttcttcctactttattaa	Protospacer
******************** .********.*

14. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_KX869741 (Enterobacter cloacae strain 20130723 plasmid R222, complete sequence) position: , mismatch: 6, identity: 0.812

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
ggtatgctttaaaaaaagactcatagtcaagt	Protospacer
    ******************** .******

15. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP027678 (Salmonella enterica subsp. enterica serovar Corvallis strain 12-01738 plasmid pSE12-01738-1, complete sequence) position: , mismatch: 6, identity: 0.812

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
ggtatgctttaaaaaaagactcatagtcaagt	Protospacer
    ******************** .******

16. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_LT994833 (Klebsiella pneumoniae isolate CNR341 plasmid CNR341, complete sequence) position: , mismatch: 6, identity: 0.812

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
ggtatgctttaaaaaaagactcatagtcaagt	Protospacer
    ******************** .******

17. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP043927 (Klebsiella quasipneumoniae subsp. quasipneumoniae strain M17277 plasmid p17277A_477, complete sequence) position: , mismatch: 6, identity: 0.812

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
ggtatgctttaaaaaaagactcatagtcaagt	Protospacer
    ******************** .******

18. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_LT882699 (Enterobacter cloacae isolate Enterobacter cloacae ENCL58 plasmid I, complete sequence) position: , mismatch: 6, identity: 0.812

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
ggtatgctttaaaaaaagactcatagtcaagt	Protospacer
    ******************** .******

19. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to NZ_CP013139 (Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence) position: , mismatch: 6, identity: 0.812

ctact-gctttaaaaaaagactcatcatcaagt	CRISPR spacer
-tattggctttaaaaaaaggctcatcatccaaa	Protospacer
 **.* *************.********* *. 

20. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to MT647605 (Pelagibacter phage Lederberg EXVC029P, complete genome) position: , mismatch: 8, identity: 0.75

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
atgtatctttaacaaaagaatcatcatcaact	Protospacer
 *..  ****** ****** ********** *

21. spacer 1.6|187934|32|NZ_CP018028|CRISPRCasFinder,PILER-CR matches to JQ340088 (Halocynthia phage JM-2012, complete genome) position: , mismatch: 8, identity: 0.75

ctactgctttaaaaaaagactcatcatcaagt	CRISPR spacer
caagtgctttataaaaacactcatcatacata	Protospacer
* * ******* ***** *********  *  

2. NZ_CP018027

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018027_1

• CRISPR_ID: NZ_CP018027_1
• CRISPR_location: 901553-903021
• CRISPR_type: Unclear
• Repeat_type: I-F
• Spacer_info: 24 spacers
• Cas_protein_info: cas6f,cas5,cas7f,cas3f,cas1,WYL

Consensus repeat of NZ_CP018027_1

Consensus_repeat	Method
GTTCATGGCCGCACAGGCCACTTAGAAA	PILER-CR
GTTCATGGCCGCACAGGCCACTTAGAAA	CRISPRCasFinder
GTTCATGGCCGCACAGGCCACTTAGAAA	CRT

spacers of NZ_CP018027_1

>1.1|901581|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
AGCCGGATGAGTAGCCGGTAATGGGGTGTGAC
>1.2|901641|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TCACTACGGCATTAGAAAAAGTCGTGAAGATG
>1.3|901701|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
ATTGCTACTGAACAGCAGATTCAAGCGTTTAA
>1.4|901761|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TGTATATGTACCCGTTATCGTAACGCTTGCGT
>1.5|901821|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TTTCAGTTTAGATAATGCGAATTTCACAACAA
>1.6|901881|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
ATACACAAGGGTTGGCCGTGCGCGTTTGGTGT
>1.7|901941|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TTACGTAAGAACCCAAGCTTTCTATTGTAAAC
>1.8|902001|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TGTACTTTCTATCGGGGGTAAAGACTCTACGG
>1.9|902061|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
AAAACGTTGATTGGTCTGACGCTGACAGTTTA
>1.10|902121|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
AGAGTGCGTAGGCAGACCTTCACCTTCGTTAT
>1.11|902181|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
ATGCGTTGCGTCGGTGTTTTCCGCATGTTCAT
>1.12|902241|33|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TTTGCGGCACTATCCGGTCTTATCTCGAATATC
>1.13|902302|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
GTACAGGGAAATAGCGAGAAGATACGGCGTAG
>1.14|902362|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
AAGCTCTTCGCTGTGAAACTCTGCGACTAAGT
>1.15|902422|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
AATGCAAAGCAACAGTTCGAAAGCAACTATAA
>1.16|902482|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
GAATAGACATAACACATCGGGTTCTCTTGCTC
>1.17|902542|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TTACGTAACGACAAATCAGCGCGTCGAAATTC
>1.18|902602|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
AGTAGCGCGAAGTAGTATGATTCGAAAGAAGC
>1.19|902662|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TTGGATGTTATCAGCATGGAAGAAATCTCCTG
>1.20|902722|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TTTCATGGCGGTGAATGGGTCAAAGTTACAGT
>1.21|902782|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
GGTGCTGGGTTCACGTTATGGCTTTGTTGAGT
>1.22|902842|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
ATTACGCACAGTTAGCAAAGTCGGGGATTAAG
>1.23|902902|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TAACAAGCGCGATGAATAATCAGGCTACACAG
>1.24|902962|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT
TTTAAGGTATGTTGGAACTGAACGTACTTTCC

CRISPR arrays and Neighbor proteins around NZ_CP018027_1

CRISPR arrays

The CRISPR arrays of NZ_CP018027_1

>merge|NZ_CP018027|1|901553-903021|PILER-CR,CRISPRCasFinder,CRT
GTTCATGGCCGCACAGGCCACTTAGAAAAGCCGGATGAGTAGCCGGTAATGGGGTGTGACGTTCATGGCCGCACAGGCCACTTAGAAATCACTACGGCATTAGAAAAAGTCGTGAAGATGGTTCATGGCCGCACAGGCCACTTAGAAAATTGCTACTGAACAGCAGATTCAAGCGTTTAAGTTCATGGCCGCACAGGCCACTTAGAAATGTATATGTACCCGTTATCGTAACGCTTGCGTGTTCATGGCCGCACAGGCCACTTAGAAATTTCAGTTTAGATAATGCGAATTTCACAACAAGTTCATGGCCGCACAGGCCACTTAGAAAATACACAAGGGTTGGCCGTGCGCGTTTGGTGTGTTCATGGCCGCACAGGCCACTTAGAAATTACGTAAGAACCCAAGCTTTCTATTGTAAACGTTCATGGCCGCACAGGCCACTTAGAAATGTACTTTCTATCGGGGGTAAAGACTCTACGGGTTCATGGCCGCACAGGCCACTTAGAAAAAAACGTTGATTGGTCTGACGCTGACAGTTTAGTTCATGGCCGCACAGGCCACTTAGAAAAGAGTGCGTAGGCAGACCTTCACCTTCGTTATGTTCATGGCCGCACAGGCCACTTAGAAAATGCGTTGCGTCGGTGTTTTCCGCATGTTCATGTTCATGGCCGCACAGGCCACTTAGAAATTTGCGGCACTATCCGGTCTTATCTCGAATATCGTTCATGGCCGCACAGGCCACTTAGAAAGTACAGGGAAATAGCGAGAAGATACGGCGTAGGTTCATGGCCGCACAGGCCACTTAGAAAAAGCTCTTCGCTGTGAAACTCTGCGACTAAGTGTTCATGGCCGCACAGGCCACTTAGAAAAATGCAAAGCAACAGTTCGAAAGCAACTATAAGTTCATGGCCGCACAGGCCACTTAGAAAGAATAGACATAACACATCGGGTTCTCTTGCTCGTTCATGGCCGCACAGGCCACTTAGAAATTACGTAACGACAAATCAGCGCGTCGAAATTCGTTCATGGCCGCACAGGCCACTTAGAAAAGTAGCGCGAAGTAGTATGATTCGAAAGAAGCGTTCATGGCCGCACAGGCCACTTAGAAATTGGATGTTATCAGCATGGAAGAAATCTCCTGGTTCATGGCCGCACAGGCCACTTAGAAATTTCATGGCGGTGAATGGGTCAAAGTTACAGTGTTCATGGCCGCACAGGCCACTTAGAAAGGTGCTGGGTTCACGTTATGGCTTTGTTGAGTGTTCATGGCCGTACAGGCCACTTAGAAAATTACGCACAGTTAGCAAAGTCGGGGATTAAGGTTCATGGCCGCACAGGCCACTTAGAAATAACAAGCGCGATGAATAATCAGGCTACACAGGTTCATGGCCGCACAGGCCACTTAGAAATTTAAGGTATGTTGGAACTGAACGTACTTTCCGTTCATGGCCGCACAGGCCACTTAGAAA

>NZ_CP018027|1|1|901553-903021|PILER-CR
GTTCATGGCCGCACAGGCCACTTAGAAA	AGCCGGATGAGTAGCCGGTAATGGGGTGTGAC
GTTCATGGCCGCACAGGCCACTTAGAAA	TCACTACGGCATTAGAAAAAGTCGTGAAGATG
GTTCATGGCCGCACAGGCCACTTAGAAA	ATTGCTACTGAACAGCAGATTCAAGCGTTTAA
GTTCATGGCCGCACAGGCCACTTAGAAA	TGTATATGTACCCGTTATCGTAACGCTTGCGT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTCAGTTTAGATAATGCGAATTTCACAACAA
GTTCATGGCCGCACAGGCCACTTAGAAA	ATACACAAGGGTTGGCCGTGCGCGTTTGGTGT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTACGTAAGAACCCAAGCTTTCTATTGTAAAC
GTTCATGGCCGCACAGGCCACTTAGAAA	TGTACTTTCTATCGGGGGTAAAGACTCTACGG
GTTCATGGCCGCACAGGCCACTTAGAAA	AAAACGTTGATTGGTCTGACGCTGACAGTTTA
GTTCATGGCCGCACAGGCCACTTAGAAA	AGAGTGCGTAGGCAGACCTTCACCTTCGTTAT
GTTCATGGCCGCACAGGCCACTTAGAAA	ATGCGTTGCGTCGGTGTTTTCCGCATGTTCAT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTGCGGCACTATCCGGTCTTATCTCGAATATC
GTTCATGGCCGCACAGGCCACTTAGAAA	GTACAGGGAAATAGCGAGAAGATACGGCGTAG
GTTCATGGCCGCACAGGCCACTTAGAAA	AAGCTCTTCGCTGTGAAACTCTGCGACTAAGT
GTTCATGGCCGCACAGGCCACTTAGAAA	AATGCAAAGCAACAGTTCGAAAGCAACTATAA
GTTCATGGCCGCACAGGCCACTTAGAAA	GAATAGACATAACACATCGGGTTCTCTTGCTC
GTTCATGGCCGCACAGGCCACTTAGAAA	TTACGTAACGACAAATCAGCGCGTCGAAATTC
GTTCATGGCCGCACAGGCCACTTAGAAA	AGTAGCGCGAAGTAGTATGATTCGAAAGAAGC
GTTCATGGCCGCACAGGCCACTTAGAAA	TTGGATGTTATCAGCATGGAAGAAATCTCCTG
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTCATGGCGGTGAATGGGTCAAAGTTACAGT
GTTCATGGCCGCACAGGCCACTTAGAAA	GGTGCTGGGTTCACGTTATGGCTTTGTTGAGT
GTTCATGGCCGTACAGGCCACTTAGAAA	ATTACGCACAGTTAGCAAAGTCGGGGATTAAG
GTTCATGGCCGCACAGGCCACTTAGAAA	TAACAAGCGCGATGAATAATCAGGCTACACAG
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTAAGGTATGTTGGAACTGAACGTACTTTCC
GTTCATGGCCGCACAGGCCACTTAGAAA

>NZ_CP018027|1|1|901553-903021|CRISPRCasFinder
GTTCATGGCCGCACAGGCCACTTAGAAA	AGCCGGATGAGTAGCCGGTAATGGGGTGTGAC
GTTCATGGCCGCACAGGCCACTTAGAAA	TCACTACGGCATTAGAAAAAGTCGTGAAGATG
GTTCATGGCCGCACAGGCCACTTAGAAA	ATTGCTACTGAACAGCAGATTCAAGCGTTTAA
GTTCATGGCCGCACAGGCCACTTAGAAA	TGTATATGTACCCGTTATCGTAACGCTTGCGT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTCAGTTTAGATAATGCGAATTTCACAACAA
GTTCATGGCCGCACAGGCCACTTAGAAA	ATACACAAGGGTTGGCCGTGCGCGTTTGGTGT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTACGTAAGAACCCAAGCTTTCTATTGTAAAC
GTTCATGGCCGCACAGGCCACTTAGAAA	TGTACTTTCTATCGGGGGTAAAGACTCTACGG
GTTCATGGCCGCACAGGCCACTTAGAAA	AAAACGTTGATTGGTCTGACGCTGACAGTTTA
GTTCATGGCCGCACAGGCCACTTAGAAA	AGAGTGCGTAGGCAGACCTTCACCTTCGTTAT
GTTCATGGCCGCACAGGCCACTTAGAAA	ATGCGTTGCGTCGGTGTTTTCCGCATGTTCAT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTGCGGCACTATCCGGTCTTATCTCGAATATC
GTTCATGGCCGCACAGGCCACTTAGAAA	GTACAGGGAAATAGCGAGAAGATACGGCGTAG
GTTCATGGCCGCACAGGCCACTTAGAAA	AAGCTCTTCGCTGTGAAACTCTGCGACTAAGT
GTTCATGGCCGCACAGGCCACTTAGAAA	AATGCAAAGCAACAGTTCGAAAGCAACTATAA
GTTCATGGCCGCACAGGCCACTTAGAAA	GAATAGACATAACACATCGGGTTCTCTTGCTC
GTTCATGGCCGCACAGGCCACTTAGAAA	TTACGTAACGACAAATCAGCGCGTCGAAATTC
GTTCATGGCCGCACAGGCCACTTAGAAA	AGTAGCGCGAAGTAGTATGATTCGAAAGAAGC
GTTCATGGCCGCACAGGCCACTTAGAAA	TTGGATGTTATCAGCATGGAAGAAATCTCCTG
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTCATGGCGGTGAATGGGTCAAAGTTACAGT
GTTCATGGCCGCACAGGCCACTTAGAAA	GGTGCTGGGTTCACGTTATGGCTTTGTTGAGT
GTTCATGGCCGTACAGGCCACTTAGAAA	ATTACGCACAGTTAGCAAAGTCGGGGATTAAG
GTTCATGGCCGCACAGGCCACTTAGAAA	TAACAAGCGCGATGAATAATCAGGCTACACAG
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTAAGGTATGTTGGAACTGAACGTACTTTCC
GTTCATGGCCGCACAGGCCACTTAGAAA

>NZ_CP018027|1|1|901553-903021|CRT
GTTCATGGCCGCACAGGCCACTTAGAAA	AGCCGGATGAGTAGCCGGTAATGGGGTGTGAC
GTTCATGGCCGCACAGGCCACTTAGAAA	TCACTACGGCATTAGAAAAAGTCGTGAAGATG
GTTCATGGCCGCACAGGCCACTTAGAAA	ATTGCTACTGAACAGCAGATTCAAGCGTTTAA
GTTCATGGCCGCACAGGCCACTTAGAAA	TGTATATGTACCCGTTATCGTAACGCTTGCGT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTCAGTTTAGATAATGCGAATTTCACAACAA
GTTCATGGCCGCACAGGCCACTTAGAAA	ATACACAAGGGTTGGCCGTGCGCGTTTGGTGT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTACGTAAGAACCCAAGCTTTCTATTGTAAAC
GTTCATGGCCGCACAGGCCACTTAGAAA	TGTACTTTCTATCGGGGGTAAAGACTCTACGG
GTTCATGGCCGCACAGGCCACTTAGAAA	AAAACGTTGATTGGTCTGACGCTGACAGTTTA
GTTCATGGCCGCACAGGCCACTTAGAAA	AGAGTGCGTAGGCAGACCTTCACCTTCGTTAT
GTTCATGGCCGCACAGGCCACTTAGAAA	ATGCGTTGCGTCGGTGTTTTCCGCATGTTCAT
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTGCGGCACTATCCGGTCTTATCTCGAATATC
GTTCATGGCCGCACAGGCCACTTAGAAA	GTACAGGGAAATAGCGAGAAGATACGGCGTAG
GTTCATGGCCGCACAGGCCACTTAGAAA	AAGCTCTTCGCTGTGAAACTCTGCGACTAAGT
GTTCATGGCCGCACAGGCCACTTAGAAA	AATGCAAAGCAACAGTTCGAAAGCAACTATAA
GTTCATGGCCGCACAGGCCACTTAGAAA	GAATAGACATAACACATCGGGTTCTCTTGCTC
GTTCATGGCCGCACAGGCCACTTAGAAA	TTACGTAACGACAAATCAGCGCGTCGAAATTC
GTTCATGGCCGCACAGGCCACTTAGAAA	AGTAGCGCGAAGTAGTATGATTCGAAAGAAGC
GTTCATGGCCGCACAGGCCACTTAGAAA	TTGGATGTTATCAGCATGGAAGAAATCTCCTG
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTCATGGCGGTGAATGGGTCAAAGTTACAGT
GTTCATGGCCGCACAGGCCACTTAGAAA	GGTGCTGGGTTCACGTTATGGCTTTGTTGAGT
GTTCATGGCCGTACAGGCCACTTAGAAA	ATTACGCACAGTTAGCAAAGTCGGGGATTAAG
GTTCATGGCCGCACAGGCCACTTAGAAA	TAACAAGCGCGATGAATAATCAGGCTACACAG
GTTCATGGCCGCACAGGCCACTTAGAAA	TTTAAGGTATGTTGGAACTGAACGTACTTTCC
GTTCATGGCCGCACAGGCCACTTAGAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018027.1|WP_071958652.1|894934_895912_+|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl|CDD|132676
NZ_CP018027.1|WP_081366480.1|911883_912447_+|DUF1566-domain-containing-protein	unknown	unknown	gnl|CDD|377878
NZ_CP018027.1|WP_071950881.1|907537_908248_+|LrgB-family-protein	unknown	unknown	gnl|CDD|377236
NZ_CP018027.1|WP_071958648.1|889945_890944_+|hypothetical-protein	unknown	unknown	gnl|CDD|225497
NZ_CP018027.1|WP_071958653.1|895908_898839_+|CRISPR-associated-endonuclease-Cas3''	cas3f	cd09673_cas3f_CAS-I-F	gnl|CDD|187804
NZ_CP018027.1|WP_071950880.1|907131_907545_+|CidA/LrgA-family-protein	unknown	unknown	gnl|CDD|377131
NZ_CP018027.1|WP_071950882.1|908528_909524_+|response-regulator	unknown	unknown	gnl|CDD|381124
NZ_CP018027.1|WP_071958650.1|892142_893339_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP018027.1|WP_071958647.1|889646_889868_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NZ_CP018027.1|WP_012517427.1|909523_910015_+|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|312075
NZ_CP018027.1|WP_071958656.1|900872_901424_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	gnl|CDD|378224
NZ_CP018027.1|WP_071958655.1|899826_900864_+|hypothetical-protein	cas5	cls000078_cas5_CAS-I-F	unknown
NZ_CP018027.1|WP_071950878.1|905722_906049_+|DUF3718-domain-containing-protein	unknown	unknown	gnl|CDD|378871
NZ_CP018027.1|WP_071958649.1|890940_892113_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271182
NZ_CP018027.1|WP_071950883.1|910105_911881_+|DUF1566-domain-containing-protein	unknown	unknown	gnl|CDD|377878
NZ_CP018027.1|WP_012517421.1|905033_905363_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP018027.1|WP_071958654.1|898842_899817_+|hypothetical-protein	cas7f	cls000079_cas7f_CAS-I-F	unknown
NZ_CP018027.1|WP_071950877.1|903924_904734_+|metallo-mystery-pair-system-four-Cys-motif-protein	unknown	unknown	gnl|CDD|188567
NZ_CP018027.1|WP_071950879.1|906195_906957_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|197918
NZ_CP018027.1|WP_071958651.1|893969_894797_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|379100

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP018027.1|WP_071958652.1|894934_895912_+|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	1.1e-143	472.7	1.0
NZ_CP018027.1|WP_071958656.1|900872_901424_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	2.4e-47	156.1	0.0
NZ_CP018027.1|WP_071958655.1|899826_900864_+|hypothetical-protein	cas5	cls000078_cas5_CAS-I-F	4.7e-151	497.4	3.5
NZ_CP018027.1|WP_071958653.1|895908_898839_+|CRISPR-associated-endonuclease-Cas3''	cas3f	cd09673_cas3f_CAS-I-F	2e-48	159.6	3.3
NZ_CP018027.1|WP_071958654.1|898842_899817_+|hypothetical-protein	cas7f	cls000079_cas7f_CAS-I-F	1.2e-178	587.7	0.4
NZ_CP018027.1|WP_071958651.1|893969_894797_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	3.1e-11	38.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP018027.1|WP_071958652.1|894934_895912_+|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl|CDD|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	5.41494e-170
NZ_CP018027.1|WP_081366480.1|911883_912447_+|DUF1566-domain-containing-protein	gnl|CDD|377878	pfam07603, DUF1566, Protein of unknown function (DUF1566). These proteins of unknown function are found in Leptospira interrogans and in several gamma proteobacteria.	2.48249e-37
NZ_CP018027.1|WP_071950882.1|908528_909524_+|response-regulator	gnl|CDD|381124	cd17593, REC_CheC-like, phosphoacceptor receiver (REC) domain of uncharacterized response regulators containing a CheC domain. This subfamily is composed of uncharacterized proteins containing an N-terminal REC domain and a C-terminal CheC domain that may function as the output/effector domain of a response regulator. CheC is a CheY-P phosphatase, affecting the level of phosphorylated CheY which controls the sense of flagella rotation and determine swimming behavior of chemotactic bacteria. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.64722e-61
NZ_CP018027.1|WP_071958648.1|889945_890944_+|hypothetical-protein	gnl|CDD|225497	COG2946, COG2946, Putative phage replication protein RstA [DNA replication, recombination, and repair].	3.8593e-23
NZ_CP018027.1|WP_071950880.1|907131_907545_+|CidA/LrgA-family-protein	gnl|CDD|377131	pfam03788, LrgA, LrgA family. This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.	5.1399e-22
NZ_CP018027.1|WP_071958653.1|895908_898839_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	5.04456e-39
NZ_CP018027.1|WP_071958647.1|889646_889868_+|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.41502e-10
NZ_CP018027.1|WP_012517427.1|909523_910015_+|PAS-domain-containing-protein	gnl|CDD|312075	pfam08448, PAS_4, PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.	2.21429e-05
NZ_CP018027.1|WP_071958656.1|900872_901424_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl|CDD|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	4.41562e-66
NZ_CP018027.1|WP_071950881.1|907537_908248_+|LrgB-family-protein	gnl|CDD|377236	pfam04172, LrgB, LrgB-like family. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance.	1.70508e-67
NZ_CP018027.1|WP_071958649.1|890940_892113_+|tyrosine-type-recombinase/integrase	gnl|CDD|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.03919e-35
NZ_CP018027.1|WP_071950883.1|910105_911881_+|DUF1566-domain-containing-protein	gnl|CDD|377878	pfam07603, DUF1566, Protein of unknown function (DUF1566). These proteins of unknown function are found in Leptospira interrogans and in several gamma proteobacteria.	1.10066e-31
NZ_CP018027.1|WP_071950878.1|905722_906049_+|DUF3718-domain-containing-protein	gnl|CDD|378871	pfam12514, DUF3718, Protein of unknown function (DUF3718). This domain family is found in bacteria and viruses, and is approximately 70 amino acids in length. There is a single completely conserved residue C that may be functionally important.	1.67391e-18
NZ_CP018027.1|WP_071950877.1|903924_904734_+|metallo-mystery-pair-system-four-Cys-motif-protein	gnl|CDD|188567	TIGR04052, hypothetical_protein_MettrDRAFT_3899, AZL_007920/MXAN_0976 family protein. Members of this rare protein family regularly occur next to a member of the MXAN_0977 subfamily (TIGR04039) of the di-heme cytochrome c peroxidase/MauG family (pfam03150). MauG itself (TIGR03791) is a protein modification enzyme responsible for the tryptophan tryptophylquinone (TTQ) modification involved in methylamine dehydrogenase activation. All members of this family have a motif of four spaced invariant Cys residues, while additional homologs outside the scope of this family lack the four Cys residues.	1.53747e-37
NZ_CP018027.1|WP_071950879.1|906195_906957_+|response-regulator-transcription-factor	gnl|CDD|197918	smart00850, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.	2.39591e-16
NZ_CP018027.1|WP_071958651.1|893969_894797_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.29683e-06

Protein sequences

>NZ_CP018027.1|WP_071958656.1|900872_901424_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MNSYIDVVLKPDAELREAELSSKVFTKFHKGLVALKTDQIGISFPKVRVKLGLVYRLHGNVDKLKELQELNWLGPLIGYCNVSDICPIPEIVQHRNVREIRSNLSSSKLRRLVTRGSIDKQGEKRYKIKMLSNSFDNPYLDILSSSTGQVYRKFFYFGEVQAEPIVGPFDSYGLSKSATIPWF
>NZ_CP018027.1|WP_071958655.1|899826_900864_+|hypothetical-protein
MKIIIEYDSCWRNSFLGGSNNEPVPKKGREFLGSMTNLKKEGNFKFHETTLNTVMGVLNRLIGDQRKLYQARNKLYEQSYYFENLEDKVSFTDKAEKTNEITFIRNMNGSKDQQSFTGMVKADDPVFTSGYSKEFLGVLKLNPSELCDFILDSGFVVNKEVRLSPLYVADLVDEILDMGSVENVNRINEAVELLTNKYSDLVTDKVPTPYIESNGKVKLIRLYSAGLYIQLERLHLRFDMSSSLSPRGSISGFSKRGYNGRRDFMNKYTTGKPKLIWGNPFIKKEKIKGQGEVTSMMTKANGQLEITIDVDRTKGHEIKTLIENAGVSSFYLGKKGLAYVSSIRV
>NZ_CP018027.1|WP_071958654.1|898842_899817_+|hypothetical-protein
MERVTGIKSVDFKIKALGHGVVNWNGPTKLKGEHPLKPYENHTMPKLRGYTNSFENEYDEGTTQKGNSFKVPRLKEAADIDFKKTPLYISQNCIRHHLFKEQSFDLHFAGEKNLEKVLASITGLIRGYVVPASQCKRTSCLLIEDFIDQLGNGNFEQFGKAGERDSSSFFSKTTFGDTEYTSYGSISIEQMQFISLDKKFDRASMIIKEGQGEQVALTVQSFIKSLDPARDPKATFHSNYVRHGTIFEEGECGILLNEEAIHTLVEHTLSRIANLSIRQAKGYMYVDEIIVDYNDSHKMMRIKRDESEIIPEPQSNYAQYFYAK
>NZ_CP018027.1|WP_071958653.1|895908_898839_+|CRISPR-associated-endonuclease-Cas3''
MMVTFVSQCEKNALKKTRRVLDAFANRIGDNTWQILITEEGLLTVKKMLRQTASKSTAVSCHWIRSRSRSELLWIVGSKSKFNSEGVVPVNKTEKEVLMDVTTGKPKKGVLYANTKLQPLAEHLFAVGYIAEQLHQKLFPYSPQFSIVNFIAGCLHDLGKIDPLFQQWVTGPKKKNYIPDDGQHIDTAKFSFEKHPRHNEISLLLCHLMDEASSQYISSKNKESIKHAIYWHHAKPFRKDKASFSTYKGIYKKFNANQKDCTFGEVVERAQILLHQVVNMDKTYRGQDVSILDRAFSKAPFSEDDSDILSSLHVPRYKEYELEESVKSNQANVKPNALNNIARSCVITADRIVSAFSANELHDAIIEQTLGNVVNEILYTESNLASEIDTCLTSFYPNSERSVKQREIAQALTHAPSVAVLAGAAGCGKTKIALEWASLQNVQKIIWVCPRVQVCQGLFYELTSEQYLPNSTIEINTGEFKFHNKWDNPIEADDYFSGDIVITTIDQLLGSVISHTKADTLIDYLNAYVVFDEFHEYVNMPAFNLLLAELVTAKKMQEKSNVLLVSATPHYLFVEELLGVEKEDIIEMPSFNTSQYQIDFKVFDDTKFNQANPLFTPQSDTTFVISNMALTAQNSFVANQHDENAVLLHSKFIKSDKRKWFSEVFESFKKGGARKFDVLRSGPIVQASLNISCNAMTTEITNAEDSLQRLGRLDRFGENDGVNVYTLAVPESIANAKGKSPAANFLSKMYTLHSTRKWYQHLLNSLEGKIFTLPEIYSLYKEFHHSEETRTFIESDLVASLKKSVEKINAQVVDPIFIPSKKQKDKGRGKIAKSSLRGDNRFVQLAMIDVSKNEPEYLEQYAYTMPLDDESDIDNLTYSTSAIQGYEQSDKDLLSYMFAKHHNIKGGKKPYKDFVLLNDARDPEYPIYLSYTTNDLLAVGGESSRHPHAIYYAICDKQPIGAISINQINQTTENEE
>NZ_CP018027.1|WP_071958652.1|894934_895912_+|type-I-F-CRISPR-associated-endonuclease-Cas1
MEQFSSMDMKAILHSKRANMFYIEYCRVIQKDGRVLYLTEEKKENLYYNIPIANTTVLLLGTGTSVTQAAMRMLSQAGVLVGFCGGKGTPLYMATEVEWLTSQSEYRPTEYLHGWLRFWFDDEKRLSAAKTLQQARIEYIESTWNRDKDLKNEGFIHGDSSIERALTTFRKRTAYATKTTDLLLTEAQLTKTLYKFAANCVSIEDFKRKHQSTDKANDFLNHGNYLAYGIAASTLWVLGIPHGFAVLHGKTRRGALVFDVADLIKDAIVLPWAFVCAKEDATEQEFRQQILQKFTDHKAMDFMFNTVKNIALQDYSSKKIEGKNL
>NZ_CP018027.1|WP_071958651.1|893969_894797_+|WYL-domain-containing-protein
MELAQRYWMLELLAYWEGKVNTKPLMHAFNISRQSASAIINKYLASNEDTLAYDVTQKAYVVTSAFNPKFINRTVDEYFDWQQVGKTPSFQSREPSTSQIRIQPLSRYVDPSVMRPLLKAMKCKTAVDCEYLSVTNNEPIGRLVYPHSFVKAANRWHVRGFCALRNNYLDFVLSRFRSVEYDGGKATYTENEDVKWNTSVDLILAPDPRLSDIQKQALEKDFNMMNGRITVKARGALVKYTLDDLQIKAKMLEADPQAQQLVCVNYSDIKRWLYE
>NZ_CP018027.1|WP_071958650.1|892142_893339_-|hypothetical-protein
MKRAIYLAGLGQEMYPMSLRDYAQRLSKALDEEDPVASNAYKAEISEMEYSQEGLSVDVVTISKSSEQDEKIVYKLYNFDYAQFLTSNYSDANILKRFLVLCLVLLARFPSLMKSFFDFNFHIKKRSKIQASYFLVIYAVLGMYLLFLIPSVLSVLNGMMNQSGDTVNNSWFGEFLNWIEPVASGIVTSFAITMMLSPASKTIFAKTAIEYLGANQYLSTGEQRQKIQGKLSKLIEEIIEKEGEDIKIELHGYSFGSVIAFDALFPKESPPGTRIKNCITSFCTIGFPLDYIEIYWDNYFSNRVYDGLFLVDWKNIWSETDVLSSSLDNDKTKKLSLIKDEQFWETISFREYSYNIFDSNSVGYLELFMFYGIRAHSMYWDRHSDSKSCLVYLAKNDN
>NZ_CP018027.1|WP_071958649.1|890940_892113_+|tyrosine-type-recombinase/integrase
MKYTKFTDGLLRQASKESFVCRDVIVPQLQFRPAKAHRKVGYFHCLYSEGGVSTSKSLGEYPIVNLQEARKQARKWLVEQHAKRYKLSSVERFTNVGELLNWYQSNIAQQELNSLRTIKNKSHRVESLLRPYLSEVSISDCSSQLLDKAWLRPLNNRFSPSTLRGAFQTLKAAFKQAHGLRYIDENPLLDLNFTMLLPASIKPKKAALAGLPLNEVVKQFQHFSPPDRFLCLLCLGFLTRNTETVMARWRDFDTEKVSWSIPEEHTKTGSALTLPLSTHSLKWLADYKRKQRRYCRSRFLFPVNQGRSSWSSSYAAQRIMNASRGRFTLHDLRKYGSTYLRDSGVDYYLVERLLNHKKTHLDATYIHTTLREPLMGVIDMWHEKINVTCK
>NZ_CP018027.1|WP_071958648.1|889945_890944_+|hypothetical-protein
MNKGVEPKTVAKNHGKLNPEQSPVFIDFLKLRVDDVEAPNPYFEMIALQLRKYDLLISHRQCNRSRGYDCAYKIVTTTQAQNVVGKIEYSERYKRVLLELTGLGCACIEKAESDYVWLQALVAQPAVTIRRIDLALDDENGLYQIEKIDKDYSRGRFNAESGKRPKKENLGNKVEGRTRYIGGPTAYKRGRFYEKGKQLKLSHCRPWMRHEVRFVSNDRDRIPDETIRNRADYFYSAFPRALQKLLGKHSVIPVTERFMREYVSDISTRVASCKRQYGPLIETLTEHHGATATCEMLSRIGRSKVIELPPFVDEVSLADCTDIIALQSGEAI
>NZ_CP018027.1|WP_071958647.1|889646_889868_+|helix-turn-helix-domain-containing-protein
MKVTTQTILLSPQEVAEQLGVTLNTLAVWRCHGSISLSYVKIGRCVRYRAEDVEAFINAHRFYHADKPVNACD
>NZ_CP018027.1|WP_071950877.1|903924_904734_+|metallo-mystery-pair-system-four-Cys-motif-protein
MKMPFRMGAMPSLLLTALLALAGCDVIDFKGREPGEIPFKLVGVDTGACPMIMSIGQDRWNIDYFGFYLSKPEVRIDGKWQRVKFKQTKWQTPNEALLKFHNKCINPDDANSKLVLDVSEELLKLATNLRFTMGLPFDVNHADALTQPSPLNDSSMFSNRRNGHQFLRLDVSKNAKETREWSYHLGSAGCGSESEAARPETSCAFTNRVEFILPMTQLDTDLDLEISVSNIVAQVDINDAESCVFASSEVSPCDKLIQNLVHRPWIKWQ
>NZ_CP018027.1|WP_012517421.1|905033_905363_+|hypothetical-protein
MTEKPFITSGRNTIIHKIRKLDLLVINGDDHPPIIVTYKGIKQYEGKVPENKRDAKMMDMELVDVTTSDVFGDEKTLVFIQTLNGKEYKIDYSKVGTSMFIKIHQDSIF
>NZ_CP018027.1|WP_071950878.1|905722_906049_+|DUF3718-domain-containing-protein
MFMSRRVTQFALIGISLSLTVSAASAASYPKALENELIAVCKAVKSDSRLQLHRAVKATGLSMRDLHDGLVCNGQDMLTFAVTHNASETAQHIARRINASPSVLTAKR
>NZ_CP018027.1|WP_071950879.1|906195_906957_+|response-regulator-transcription-factor
MIALVFLQSVAMQTSLCTMLEKIGLFRHVYGAHSVGHSLALAEKHPQSIGFYSVSKSSRNLASKHWLAVGDKDEEAMLAFNHNASGFITSPFDEQQVRCTVEHVKAKHYCHKRDVQFNLLVKGLCKQYGVSESALLATLRQQLYKNAQPNVVGIRAENGWCCLNPADIKWIEAAGDYMCVQTLSESYIVRTTLCHLLKRLGEHHFKRCNRSVAVNAKYVMHIEQKLNQQRVVMRGGEAFKITHKYYYQYWHTG
>NZ_CP018027.1|WP_071950880.1|907131_907545_+|CidA/LrgA-family-protein
MRNAINTVVGAVLVFTAYYVGLLIVNLTSLPVPGPLVGLLLLVGVLFAFPQTERQVARAVTFPLKHMSLLFVPAVLGVSIYWSDIKANALAIAIAIIITTLCCLGLTAWLTQALLNSKSTHKTQLNNTNKNEGDTND
>NZ_CP018027.1|WP_071950881.1|907537_908248_+|LrgB-family-protein
MIEALNHAFSLRGLFWISVSIVSYIAALWVNRLCKGHPAAHPIVTTALLVSLGLYLTHTSVTAYQHAASLLYWLLGPITVALALPIYRQWQKLKHYGWRLLVSIAFGGVLAPIGAWLTLFVLDAPRAMQFTMLAKSITTPLAMETSAQIGGIPALAAVFVIVTGVVGAIIATSMFSLFNVTNRQAQGIALGTVAHAVGTAKAIQMGEDVAAMATLGLCVNGIFTAVALPIVFGLFI
>NZ_CP018027.1|WP_071950882.1|908528_909524_+|response-regulator
MFSVLVCDDSLVARKQVAKCLPQDWEVAVHFAKNGQEALTALAEGKGDLLLLDLNMPVLDGYGTLEAIQKQSLKTKVIVVSGDIQPEAHDRVTSLGALDFIRKPVDPKKLAEVLDKYNILHAEEEDVVEASPLDPDIRDCYQEITNIAMGQAGDHLARTMNVFVELPIPNVNLIEVSELHMMLSDIECHEQVTAVCQGFLGPGVSGEALCILSDSSFDDVAKILNVEGEVDDQLQLELLMDAASILIGTCLTGLANQMDINFSQGHPIVLGQHRAITEIIAMNQIKWKRTLAIELSYGLEGYNVQCDLILLFTEESMKMMNSKLAHLLEDF
>NZ_CP018027.1|WP_012517427.1|909523_910015_+|PAS-domain-containing-protein
MSQHLDEFQEFHWMMDMLQTVDVGIVVLDRNFTVKVWNGFMESHSGLLPSEVRDKTLFSLFPAIKQDWFMKKAKPVFDLKTRAFMTWEQRPYLFKFPNYRPITGSESFMYQNITLSPLTSTTGKVDFISMMIYDMTDVAVGKKQLEALQVTMSEAQEAKSSYS
>NZ_CP018027.1|WP_071950883.1|910105_911881_+|DUF1566-domain-containing-protein
MQFNVFSISSYFPRAIVRGLVLFATALLLAACGGGGGGGDGDSGGDGGSGSGDLVINAGPDATVTEGVTYTLSAQVSGGDGTYTYNWSASPSLSITHEDTSDSAASFVAPLVNNATEYTLTVSVNDQSGNTASDFTVITVAPVNIAPEASIDVPEWDGLPANTFPGGVEVIFDGTGSSDSDSASSDGDISDYVWTQTSGTNVITGVDTNLSTLTIVTPIANEEQQLTFQLEVTDSEGDTDVETVTITVQSETDTLPVVSAGVSQGVFSGEVVILEGEASTSIPSALPLTYSWERSNNVSSTDSGVTIRSVDDSDALSTFAIAPAVTTSTVVAYTLTVTDANGNSVEDTINVQIRPMPTPLLNDTGFLQQATNNALTEAQQNDFPGQDGQRGADIIEQNGLIEKAGRGKAGFDFTRLNANGDEQDASADTWSCVRDNVTGLVWEVKTDDGAFQDKDYTYSWYSEEVNGGFEGDQTGLNATCLLTSCNTSAYVQAVNAQGLCGFYDWRLPTHDELFSLMHLGIADDVAIDEDYFPNTGAVTNEPLWYWTSVPSADGVNSDDAQNAWALDFDSGVDNFLNKSSAARVRLVRAGR
>NZ_CP018027.1|WP_081366480.1|911883_912447_+|DUF1566-domain-containing-protein
MNKVVNVKKRNSLVLSSVKTLFASALLACTSLSTFAQECLSDGLETTPNDNFEAVTTSSLLDTTTDLVWKRCAEGQTWDGSTCSGEAVKYTWQQALVLAHEASNDDLLGWRLPNVKELATLTERDCVRPAINSSLFPATPPDDFWTSTPSADDPDRAWVVAFFNASHSIKEKDRFIYVRLVRTYTNE

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018027_1	1.15|902422|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	902422-902453	32	MK241539	Alteromonas phage P24, complete genome	8614-8645	0	1.0
NZ_CP018027_1	1.1|901581|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	901581-901612	32	NZ_CP018001	Rhizobium sp. Y9 plasmid pY9, complete sequence	364327-364358	7	0.781
NZ_CP018027_1	1.1|901581|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	901581-901612	32	CP036360	Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence	465466-465497	7	0.781
NZ_CP018027_1	1.3|901701|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	901701-901732	32	MG945333	UNVERIFIED: Microviridae sp. isolate 2135-1801, complete genome	4010-4041	8	0.75
NZ_CP018027_1	1.13|902302|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	902302-902333	32	MK047639	Phage NGI4, complete genome	24350-24381	8	0.75
NZ_CP018027_1	1.19|902662|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	902662-902693	32	MK737937	Raoultella phage RP180, complete genome	21454-21485	8	0.75
NZ_CP018027_1	1.6|901881|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	901881-901912	32	NC_001902	Methanobacterium phage psiM2, complete genome	12334-12365	9	0.719
NZ_CP018027_1	1.20|902722|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	902722-902753	32	NC_024216	Bacillus phage CAM003, complete genome	147038-147069	10	0.688
NZ_CP018027_1	1.20|902722|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	902722-902753	32	KJ489400	Bacillus phage Hoody T, complete genome	146232-146263	10	0.688
NZ_CP018027_1	1.20|902722|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT	902722-902753	32	MF498901	Bacillus phage Anthony, complete genome	148418-148449	10	0.688

1. spacer 1.15|902422|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to MK241539 (Alteromonas phage P24, complete genome) position: , mismatch: 0, identity: 1.0

aatgcaaagcaacagttcgaaagcaactataa	CRISPR spacer
aatgcaaagcaacagttcgaaagcaactataa	Protospacer
********************************

2. spacer 1.1|901581|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018001 (Rhizobium sp. Y9 plasmid pY9, complete sequence) position: , mismatch: 7, identity: 0.781

agccggatgagtagccggtaatgg----ggtgtgac	CRISPR spacer
agccggatgagcagccggtgatgagaacggtg----	Protospacer
***********.*******.***.    ****    

3. spacer 1.1|901581|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to CP036360 (Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence) position: , mismatch: 7, identity: 0.781

agccggatgagtagccggtaatgg----ggtgtgac	CRISPR spacer
agccggatgagcagccggtgatgagaacggtg----	Protospacer
***********.*******.***.    ****    

4. spacer 1.3|901701|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to MG945333 (UNVERIFIED: Microviridae sp. isolate 2135-1801, complete genome) position: , mismatch: 8, identity: 0.75

attgctactgaacagcagattcaagcgtttaa	CRISPR spacer
gtcgctgctgaaaagcagattcaagctgccaa	Protospacer
.*.***.***** *************  ..**

5. spacer 1.13|902302|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to MK047639 (Phage NGI4, complete genome) position: , mismatch: 8, identity: 0.75

gtacagggaaatagcgagaagatacggcgtag	CRISPR spacer
gttagatgaaatagcgagaatgtacggcgttg	Protospacer
**  .. ************* .******** *

6. spacer 1.19|902662|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to MK737937 (Raoultella phage RP180, complete genome) position: , mismatch: 8, identity: 0.75

ttggatgttatcagcatggaagaaatctcctg	CRISPR spacer
agggatgttatcagaatggcagaaattgccgt	Protospacer
  ************ **** ******. **  

7. spacer 1.6|901881|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to NC_001902 (Methanobacterium phage psiM2, complete genome) position: , mismatch: 9, identity: 0.719

atacacaagggttggccgtgcgcgtttggtgt	CRISPR spacer
ctacacaaaggttggcggtgcgcgtgtacgcc	Protospacer
 *******.******* ******** *.   .

8. spacer 1.20|902722|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to NC_024216 (Bacillus phage CAM003, complete genome) position: , mismatch: 10, identity: 0.688

tttcatggcggtgaatgggtcaaagttacagt	CRISPR spacer
aaacgaggcggtaaatgggttaaagttactca	Protospacer
   *. ******.*******.********   

9. spacer 1.20|902722|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to KJ489400 (Bacillus phage Hoody T, complete genome) position: , mismatch: 10, identity: 0.688

tttcatggcggtgaatgggtcaaagttacagt	CRISPR spacer
aaacgaggcggtaaatgggttaaagttactca	Protospacer
   *. ******.*******.********   

10. spacer 1.20|902722|32|NZ_CP018027|PILER-CR,CRISPRCasFinder,CRT matches to MF498901 (Bacillus phage Anthony, complete genome) position: , mismatch: 10, identity: 0.688

tttcatggcggtgaatgggtcaaagttacagt	CRISPR spacer
aaacgaggcggtaaatgggttaaagttactca	Protospacer
   *. ******.*******.********   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	931617 : 940282	6	Streptococcus_phage(16.67%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP018027|931617:940282|DBSCAN-SWA
CTTATTGACCTTTGATTTCACTAATACCTTTATAGGTTGCTGCGTCACCTAATGCTTCCTCAATGCGAAGAAGTTGGTTGTACTTAGCAACACGGTCAGAACGACATAGTGAACCCGTCTTGATTTGGCCAGCCGCTGTACCTACTGCAAGGTCAGCAATGGTGGCGTCTTCTGTTTCACCAGAACGGTGAGAGATAACCGCTGTAAAGCCAGCGTCTTTTGCCATTTTAATTGCGTTAAGGGTTTCAGTTAGTGAACCGATTTGGTTGAACTTGATAAGGATTGAGTTGCCAATACCGTTATCAATACCGCGCTTAAGGATTTTGGTGTTAGTTACAAACAAGTCGTCGCCAACTAGCTGTACTTTGTCACCAATCTTCTTAGTTAGGCTTGCCCAGCCGTCCCAGTCGCTTTCGTCTAGGCCGTCTTCAATAGATACAATTGGGTACTGTGCAGAAAGGTCAGCAAGGTAGTCGCCAAACGCTTCTGAATCGAAGCTCTTGTCTTCGCCAGATAGAACGTATTTGCCTTCTTTGTAGAATTCAGACGCCGCACAGTCTAGTGCAAGTGTGATGTCTTCATTCATTTTATAGCCAGCGTTTTCAACGGCTTCAACGATAACAGCAAGTGCTTCAGCGTTTGAGCTAAGGTTAGGGGCAAAACCACCTTCGTCACCAACCGCTGTGTTTAGACCTTTGGCAGAAAGTACTTTCTTAAGTGCGTGGAAAATTTCCGCGCCCATACGTAGTGCTTCTTTAAAGCTCTTCGCGCCTACTGGCTGAACCATGAACTCTTGAATGTCTACGTTGTTGTCAGCGTGCTCACCACCGTTGATGATGTTCATCATAGGAACAGGCATTGAGTACTGACCAGATGTGCCGTTTAGGTCTGCAATGTGCTCGTAAAGTGCTACGCCTTTTTCAGCCGCTGCCGCTTTTGCTACAGCAAGAGAAACCGCAAGGATCGCGTTCGCGCCCAGTGTTTCTTTGTTTTCTGTGCCATCAAGGTCAATCATGATGCCGTCGATATCAGCTTGTGCTAGTGCGTCTTTGCCTAGTAATGCTGGTGCAATGGTATCGTTAATCGCTGCAACTGCTTTTGTTACGCCTTTACCTAGGTAACGAGACTTGTCGCCGTCGCGTAGTTCTAGTGCTTCGCGGCTACCAGTAGAGGCACCTGATGGTGCAGCAGCACGGCCCATTGCGCCTGATTCTAAGTATACATCTGCTTCTACAGTAGGATTTCCGCGTGAATCTAAGATTTCGCGTCCGATAATGCGACTAATTTTCGCCATGTTTTTTCCTCAACAATGTAATGGGGCGCAACGGGAGAGAGCGCCCCTTTTATTAGAAATTAGTGATTTTCTTTCTGGTACTTTCCTGCCGCAGCAACGAAACCAGTAAATAAAGGGTGTCCATCCCGAGGCGTTGATGTGAACTCAGGGTGGAATTGGCCCGCAATGAACCAAGGATGATCAGGGATTTCCACTACTTCTACAAGTCGCTTGTCAGTGGACAAACCACTTACTTTCAATCCTGCTGCTTCAATTTGATCGCGAAGATTATTGTTCACTTCGTAACGGTGACGGTGGCGCTCGTAGATCTCAGCGTTGCCGTACATCTCGTGTACTTTTGTCCCTTCAATGAGGTGGCAAAGCTGGCTACCTAAACGCATTGTACCGCCAAGGTCTGATGTTTCAGTGCGCACTTCGGTCGTACCCGCAGCGTCCAACCACTCGGTAATAAGGCCAACAACTGGGTAAGGTGTTTCAGGGTCGAACTCTGTGCTGTTCGCTTTTTCCATGCCGGCAACGTTACGTGCGTATTCGATAAGCGCTACCTGCATACCCAAACAAATTCCTAAGTATGGCACCTTGTTTTCGCGCGCATAGCGGGCTGCCGCAATTTTACCTTCAATACCGCGCTCACCAAAGCCGCCAGGCACTAAGATAGCATCTAACTGCTCTAAAATTTGTGTGCCTTTGCTTTCCACATCTTGTGAGTCAATGTGATGAATATTCACAGTAAGACGGTTTTTAAGGCCGGCGTGTTTAAGCGCTTCATTAACTGATTTATAAGCATCAGGCAGTTCTACGTACTTCCCAATCATGCCGATATTAACTTCAGCGGTAGGGTTAGATTCTGCGTAAAGTACCTGTTCCCACTCAGACAAGTCGGCTTCATTACATTCAAGACCGAAGCGGTCAACAACCAGCTGATCCATACCCTGAGCTTTAAGTGCGGCAGGAATACGGTAAATACTGTCTACGTCTTTTAATGAAATAACGGCTTTATCAGCAACGTTAGTGAACAGCGCAATTTTAGAGCGTTCACTGGCTGGCAATGCACCGACAGAACGGCACACTAAAATGTCTGGCTGAATACCAATAGAGCGAAGCTCTTTTACCGAGTGCTGCGTTGGCTTGGTTTTAACTTCGCCCGATGCAGGCATGTAAGGCACAAGTGTTAAGTGCATGAACATAGCGCGTTCACGGCCCACTTCAGTACCAAGCTGACGAATAGCTTCTAAGAAAGGTTGTGACTCGATGTCACCTACGGTTCCGCCCACTTCAACAATAGCCACATCATGACCTTCAGCACCTTCGATAACGCGGCGCTTAATTTCATTGGTAATGTGAGGGATAACCTGAATGGTTGCACCTAAGTAATCACCGCGACGCTCACGCTTCAGTACTTCTTCATATACCCGGCCGGTTGTGAAGTTGTTGCGCTTGGTCATACGGGTGCGAATAAAACGCTCATAGTGACCAAGATCAAGGTCGGTCTCTGCGCCGTCATCGGTAACAAATACTTCACCATGCTGGATGGGGCTCATTGTGCCCGGGTCGACATTGATGTAAGGGTCGAGTTTTAACATGGTTACGGTGAGACCGCGAGCTTCCAGAATTGCGGCTAATGATGCTGCAGCAATACCTTTACCTAGCGATGAAACTACACCACCTGTGACGAAAATATAATTTGTCATGCGAAACCTAGAACGTTTGGGTTGTATGGTAAATATAGGCTGAGTTTAGAACAAAACCAGCTACACTTTGGACGGGGCGATAGTATACGCAAATTCATGTGGGCAGACAATCAATTTGCCCACATGATGCGCAATTTTACGATTGACTTAAGCGTTTAAGGGTGTAGATGAGGTCAAGCGCTTGGCGCGGAGATAGCTCATCGGGCGATAAGTTTTCAAGCGCTTCCACCACGGGGTGCGGTTTGTCTGGAAAAAGCATTTCTGCTTGTCCTTTCGCATTCGAACCGTTGTCAATTTTTCTGGAGGTGTCGCTTTGCGCTTGCGAAGTGTCACTGCCCCTTGATTCATCACTGGTCATGACGTGCGATGATTCTAAAATAGCGAGCTTTTGCTGAGCGGCTTTGATCACAGGTTTTGGTACACCAGCAAGTTGTGCAACTTGTAAACCAAAGCTCTTGTTCGCGGCGCCTTCAGATACGGTATGCATAAAGCGAATGGTGTCTTCAAACTCCATCGCATTAAGATGCACGTTCACAACGCCCGCTTGCGTTTCGGGTAGCTCGGTCAGCTCAAAATAGTGGGTCGCAAAAAGGGTGTAGGCATTTAGCTGCTTCGCCAAGTAGCTCGCGCAGGCCCATGCCAGCGATAAACCATCATAGGTGCTGGTACCACGGCCAATTTCATCCATTAACACCAGTGAGTTTTCAGTCGCGTTATTAAGAATATTTGCCGTTTCGGTCATTTCAACCATGAAGGTTGAGCGGCCAGAGGCCAGGTCATCTGATGCGCCAATCCGGGTGAATATGCGATCCAGCTTGCCGATGTGGGCGTTTTCAGCAGGCACATAACTGCCGATGCAGGCCAATAAAGCAATAAGCGCTGTTTGACGCATGTAGGTCGATTTACCGCCCATGTTTGGGCCGGTAATAACGAGCATACGGCGCTCAGTATCCAGTTGCAGTGGGTTGGCAATGAAGGGGTCTTTCATCACGTTCTCAACCACAGGGTGGCGACCGGCATCATAAGTAAGCGCACATTCTTGGCTCAATTTTGGCCGATGCCAATCGAGCGATACCGCGCGTTCGGCAAAACAGCACAGCACGTCGAGCTTGGCAAGCGCTGCGGCGGTTTCAATTAACTTGTTGAGGTATGGCGCAAAATTGTCGAACAAGGCTTCATAAAGCTGTTTTTCAAGGGCAAGTGCAGCCCCTTGGCTACTTAGCACTTTGTCTTCGTGCTCTTTAAGCTCAGGTGTAATGTAACGTTCGGTGTTCTTAAGGGTCTGTCTTCGGATGTATTCGGCGGGGGCCAAAGCGCTGTTAGCACGACTAATTTCAATAAAAAACCCGTGCACTTTGTTATAGCCCACTTTCAATGTGGAAATGCCTGTGCGTTCACGCTCACGTTGCTCCATCGCATCTAAGTAGTCGGTAGCGCCTTGTGATAGCTTACGCAATTCATCAAGTTCAGCATTATAGCCTTCGGCAATTACGCCACCATCGCGTATAACAACTGGTGGGTTATCGATTATAGCGCTGTTTAACAGGGCTTGAAGCTCAGGGTAAGTGCCAATGGTTTCGCCAATACTTCTAATTTGTCCTGTGTCGAAACGGGCAAGGGCATCTTGTAAATCAGGCAGTGCATTAAACGCATTTTTTAAACGTGCAAAATCCCGAGGGCGCGCCGAGCGAAGGGCTAAACGCGCCATAATACGCTCTATGTCGCCAATGTGTTTTAGCGCACTGCGGATATCTTCAGGATCGTCATTAATAAAGGTGTCTATTGCGTCTAAGCGGCTTTGGAGCTCATGCTGGTCGGTCAGCGGCGAGTGAATGATTCGCTGTAACATACGACTGCCCATGGCCGTGGTGGTGGTATCCATTACGCTGAACAGGGTATTTTCCTGACCGCCAGACAAATTATGGGTAAGTTCCAGGTTTCTGCGCGTTGCGGCATCAAGCTGAACACGGCTGTCTTGCTGTTCAGTCTGAATGCGGCGAATGTGGGGCAGGGCAGTGCGCTGGGTATCTTTTACATATTGTAAAACACAACCTGCTGCGCCTAAGCCTTTAGTGACGCCTTTTATACCAAAGCCATCTAAGGTTTTGGTTTCAAACTGGGCGTTAAGCTGTTCATTTGCAGTATCTACGTCGAATTCCCACTCGGGACGCCTGCGTAGCCCTTTGCGATTTTCAACAAGAGACAGGCTTTCAAAGCCTTCAGGGTAAAGTAACTCAGCCGGGTTAATGCGCTGAATTTCAGCCAGTAAGCTTTCATCACTATCGCACTCGAACACCACAAAGCGACCGCTAGTTACATCTAATGTGGCTAACCCATAATGCATGCTATGGCCGCACACAGCGGCAAGAATATTGTCGCGACGCTCTTCTAATAAAGCTTCGTCGGTTACAGTGCCTGGCGTAACAATGCGCTGAACGGCACGCTCAACGGGGCCTTTGCTCGTCGCTGGGTCGCCAACTTGTTCACAAATGGCGACCGACTCCCCCATTTTCACTAAACGCGATAAGTAGCTTTCTACCGCATGATAAGGCACGCCTGCCATGGGAATGGGCTCGCCACCTGATTTACCTCGCGCCGTAAGCGAAATATCCAGTAATTCAGCAGCTTTTTTGGCATCGTCATAAAATAACTCGTAAAAATCGCCCATGCGATAAAAAAGTAGAATATTCGGATGTTGCGCCTTTATGCTTAAATATTGGCGCATCATAGGAGTATGTGATTCCAAAAAATGCCTCTGCGAATTTGTTGCTGGGTTTAATGCCTGTTGAAGGGAATAAATGATAAACTCACCCTCTTTAAGATCAAGCGCAGATCTTATGAATAACAGATCTGGTGAATAACAACAGGTGTAACTAGGTATCTCTAAAATGAACGGGACATTTTCAACTGATTCGACAGTAAACGCCACCCCTTTAAGGCTTGATAGTGCATTATCTGCTCAAATTCAGGTATTGGGCGATGCACTTCGAGCAAAAGGTTGGAGTGTGTCTAGCGCAGAGTCCTGTACGGGCGGAGGTATAGCCTTTGCTTTTACCAGTGTATCGGGCAGCTCGGATTGGTTTAATCAATCATGGGTAACCTACTCAAACAGTGCTAAACAAAGCCGCTTGGGCGTTACCGAGCAAACGCTAGTAGAGTATGGCGCCGTGTCTCAGCAAACGGTAAAAGAAATGGCGGACGGAGTACGCCGCAATAGTGGTGCGCAACTCGTTGTTACCGTAAGCGGGATTGCTGGCCCAAATGGTGGCAGTGAAGAAAAGCCGGTGGGTACTGTATGGTTCGGTTTTTTATGTGGCGAAAAAGCGGAACAAATTAAACAAGTATTTAGCGGTGACAGAGATGAAGTTCGCCATCACGCGATCGCTTTTGCTATTTCTCACTTAGTAAAATTGTTGAGTGAAAATTAAAAACACGGGTTGAAACTGTATGCTTGTACAGTATAGAATGTGATCATTATTTGATACCGTCATTAAATGAATAGGCGATGTCAAAACAGAATTTAACCGCAAATCCTAGAGGATACATACGTGGACGATAACAAATCAAAAGCTTTAACCGCCGCAGTAGGCCAAATTGAAAAGCAATTTGGTAAAGGCGCTATCATGCGCTTAGGCGACAACCAAGCCATGGATATTGAAGCGATTTCTACTGGCTCACTAACCATTGATATCGCTCTAGGCATAGGCGGTTTACCGTGTGGTCGTGTTGTAGAAATTTACGGCCCTGAATCATCAGGTAAAACCACGCTAACACTCCAAGTTATCGCTGAAGCGCAGAAAAATGGTAAAACCTGTGCGTTCGTTGACGCTGAACACGCCCTAGACCCTGTATACGCCGAAAAGTTAGGCGTAAACATTGACGAGCTATTGGTATCCCAGCCTGACACTGGTGAGCAAGCACTAGAAATTTGCGACATGTTAGTTCGCTCTGGTGCCGTAGACGTCGTTATTGTTGACTCGGTTGCTGCACTTACACCAAAAGCCGAAATTGAAGGTGACATGGGTGATTCTCACGTTGGTCTTCAGGCCCGCTTGATGTCACAGGCGCTGCGTAAGCTTACGGCAAACATTAAGCGTTCAAACACCCTTTGTATCTTCATTAACCAAATTCGTATGAAGATTGGTGTAATGTTTGGTAACCCAGAAACGACAACGGGTGGTAACGCGCTTAAGTTCTACTCTTCTGTTCGTCTAGACATTCGCCGTATTGGTGCAGTTAAAGAAGGCGATGAGGTAGTGGGTAACGAAACCCGCGTGAAGGTAGTGAAAAACAAGGTTGCGCCACCGTTCAAGCAAGCTGAATTTATGATCCGCTACGGTGAAGGGATCAGCAAAGAAGCAGAGCTTATTGACCTAGGTGTTAAGCAGAAGCTTGTTGATAAAGCCGGCGCTTGGTACAGCTATAAGGGTGACCGTATTGGTCAAGGTAAAGCAAACGTAATGAAGTACCTTAAAGAACACCCAGAGACAGCAAACGAGATCGAAACGAAGATCCGCCAAGAGCTTTTGCTTTCTAAAACAGTGAAGGCAGAAGAAGCATTGCCGCAGGGTGAAGACGACGTACTTCCTGAGTAAAATTAACGCTTCATAGCGATTAAAAACCCACCCTTTGGTGGGTTTTTTTGTATCTGCATTTTATACCTTCGACAATACATATTTATTAACACTTCTTGGTAACCTAGAACTTGTACAAAAAAGAAAAACAGGGAATGCTGTAATAAATATTTAGTTGTTCAGACTACTAAGAGTAAATAAGGCAAGCCTTGCGAGTAAATTAGGGCAAGCCTATAACAATAATGAACAGTATTAACTGTTTATAAGAGAGAAGAGGGAAAGGGAATGATTGAAATATCAGGTCTCGCCAAACGCTTTACGGTGGAAAACCCGAAAAAGCTTAGCGAACAAGAGAAGAAGGACCCGCGTTTAAAAGGGCGTTATTTTCAGTCTGTAAGGGATGTGTCTTTTACTTGCGAAAAAGGTCAGGTTCTTGGACTGTTAGGACCTAACGGCGCAGGTAAAACCACTACATTGCGTATGCTTTCAACAGCGCTTAAACCCGACAGTGGCAAAGTACTCATAGGTGGCGAGGACGTACTTTCTAACCCCAACATTGCGCGAAAGAAAATTGGTTTTCTTTCGAGTTCAACAGGTCTATATGGCCGTTTAAGCGGGCGTGAGAATATTAGCTACTTCGGTGAGCTACACGGCATTTCAAAAAATGTGATTAAGGCACGTATTGAAGAGTTAGCTGACTTGCTCGATATGCAAACCTTCCTTGATAGAAGAGCGGAGAATTTTTCATCAGGCATGAAACAAAAAGTGTCGATTGCTCGGGCTGTTATTCACGAGCCAGAACTGGTGGTACTTGATGAACCTACAACCGGCCTTGATATTATGGCAACCAGTACCGTTATGGAATTTATCCAACGCCTTAAGGATAAAGGTACCCCGGTTATTTTCTCTACTCACCATCTTGATGAGGTGAAAACCCTTTGCGACAAGGTGACCGTGATTAACCAAGGGGAAACCGTATTTAACGATTCGCTTGCCGCTTTTAGTGCTTTGTCTGGCAATGAAGGGGCCAGCGGTCAGATGCACAAGAGCTTTCTAAAAACACTATCAATGGATACTGAGGAGACGGGCAATGTGGTTAATTTTTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP018027|931617:940282|939460_940282_+|WP_071950894.1|DBSCAN-SWA
MIEISGLAKRFTVENPKKLSEQEKKDPRLKGRYFQSVRDVSFTCEKGQVLGLLGPNGAGKTTTLRMLSTALKPDSGKVLIGGEDVLSNPNIARKKIGFLSSSTGLYGRLSGRENISYFGELHGISKNVIKARIEELADLLDMQTFLDRRAENFSSGMKQKVSIARAVIHEPELVVLDEPTTGLDIMATSTVMEFIQRLKDKGTPVIFSTHHLDEVKTLCDKVTVINQGETVFNDSLAAFSALSGNEGASGQMHKSFLKTLSMDTEETGNVVNF
>NZ_CP018027|931617:940282|934737_937329_-|WP_081366481.1|DBSCAN-SWA
MMRQYLSIKAQHPNILLFYRMGDFYELFYDDAKKAAELLDISLTARGKSGGEPIPMAGVPYHAVESYLSRLVKMGESVAICEQVGDPATSKGPVERAVQRIVTPGTVTDEALLEERRDNILAAVCGHSMHYGLATLDVTSGRFVVFECDSDESLLAEIQRINPAELLYPEGFESLSLVENRKGLRRRPEWEFDVDTANEQLNAQFETKTLDGFGIKGVTKGLGAAGCVLQYVKDTQRTALPHIRRIQTEQQDSRVQLDAATRRNLELTHNLSGGQENTLFSVMDTTTTAMGSRMLQRIIHSPLTDQHELQSRLDAIDTFINDDPEDIRSALKHIGDIERIMARLALRSARPRDFARLKNAFNALPDLQDALARFDTGQIRSIGETIGTYPELQALLNSAIIDNPPVVIRDGGVIAEGYNAELDELRKLSQGATDYLDAMEQRERERTGISTLKVGYNKVHGFFIEISRANSALAPAEYIRRQTLKNTERYITPELKEHEDKVLSSQGAALALEKQLYEALFDNFAPYLNKLIETAAALAKLDVLCCFAERAVSLDWHRPKLSQECALTYDAGRHPVVENVMKDPFIANPLQLDTERRMLVITGPNMGGKSTYMRQTALIALLACIGSYVPAENAHIGKLDRIFTRIGASDDLASGRSTFMVEMTETANILNNATENSLVLMDEIGRGTSTYDGLSLAWACASYLAKQLNAYTLFATHYFELTELPETQAGVVNVHLNAMEFEDTIRFMHTVSEGAANKSFGLQVAQLAGVPKPVIKAAQQKLAILESSHVMTSDESRGSDTSQAQSDTSRKIDNGSNAKGQAEMLFPDKPHPVVEALENLSPDELSPRQALDLIYTLKRLSQS
>NZ_CP018027|931617:940282|938149_939196_+|WP_012517447.1|DBSCAN-SWA
MDDNKSKALTAAVGQIEKQFGKGAIMRLGDNQAMDIEAISTGSLTIDIALGIGGLPCGRVVEIYGPESSGKTTLTLQVIAEAQKNGKTCAFVDAEHALDPVYAEKLGVNIDELLVSQPDTGEQALEICDMLVRSGAVDVVIVDSVAALTPKAEIEGDMGDSHVGLQARLMSQALRKLTANIKRSNTLCIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGAVKEGDEVVGNETRVKVVKNKVAPPFKQAEFMIRYGEGISKEAELIDLGVKQKLVDKAGAWYSYKGDRIGQGKANVMKYLKEHPETANEIETKIRQELLLSKTVKAEEALPQGEDDVLPE
>NZ_CP018027|931617:940282|931617_932910_-|WP_071950893.1|DBSCAN-SWA
MAKISRIIGREILDSRGNPTVEADVYLESGAMGRAAAPSGASTGSREALELRDGDKSRYLGKGVTKAVAAINDTIAPALLGKDALAQADIDGIMIDLDGTENKETLGANAILAVSLAVAKAAAAEKGVALYEHIADLNGTSGQYSMPVPMMNIINGGEHADNNVDIQEFMVQPVGAKSFKEALRMGAEIFHALKKVLSAKGLNTAVGDEGGFAPNLSSNAEALAVIVEAVENAGYKMNEDITLALDCAASEFYKEGKYVLSGEDKSFDSEAFGDYLADLSAQYPIVSIEDGLDESDWDGWASLTKKIGDKVQLVGDDLFVTNTKILKRGIDNGIGNSILIKFNQIGSLTETLNAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEEALGDAATYKGISEIKGQ
>NZ_CP018027|931617:940282|932969_934601_-|WP_012517444.1|DBSCAN-SWA
MTNYIFVTGGVVSSLGKGIAAASLAAILEARGLTVTMLKLDPYINVDPGTMSPIQHGEVFVTDDGAETDLDLGHYERFIRTRMTKRNNFTTGRVYEEVLKRERRGDYLGATIQVIPHITNEIKRRVIEGAEGHDVAIVEVGGTVGDIESQPFLEAIRQLGTEVGRERAMFMHLTLVPYMPASGEVKTKPTQHSVKELRSIGIQPDILVCRSVGALPASERSKIALFTNVADKAVISLKDVDSIYRIPAALKAQGMDQLVVDRFGLECNEADLSEWEQVLYAESNPTAEVNIGMIGKYVELPDAYKSVNEALKHAGLKNRLTVNIHHIDSQDVESKGTQILEQLDAILVPGGFGERGIEGKIAAARYARENKVPYLGICLGMQVALIEYARNVAGMEKANSTEFDPETPYPVVGLITEWLDAAGTTEVRTETSDLGGTMRLGSQLCHLIEGTKVHEMYGNAEIYERHRHRYEVNNNLRDQIEAAGLKVSGLSTDKRLVEVVEIPDHPWFIAGQFHPEFTSTPRDGHPLFTGFVAAAGKYQKENH
>NZ_CP018027|931617:940282|937489_938029_+|WP_012517446.1|DBSCAN-SWA
MNGTFSTDSTVNATPLRLDSALSAQIQVLGDALRAKGWSVSSAESCTGGGIAFAFTSVSGSSDWFNQSWVTYSNSAKQSRLGVTEQTLVEYGAVSQQTVKEMADGVRRNSGAQLVVTVSGIAGPNGGSEEKPVGTVWFGFLCGEKAEQIKQVFSGDRDEVRHHAIAFAISHLVKLLSEN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071950893.1|931617_932910_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	8.5e-135	59.7
WP_012517444.1|932969_934601_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.2e-147	50.2
WP_081366481.1|934737_937329_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	3.8e-33	21.8
WP_012517446.1|937489_938029_+	CinA family protein	B5TK85	Pseudomonas_phage	1.0e-25	45.2
WP_012517447.1|938149_939196_+	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	2.5e-116	62.8
WP_071950894.1|939460_940282_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	4.1e-26	32.6