CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018102	Enterococcus faecalis strain L12, complete genome	4 crisprs	csa3,cas3,cas9,cas1,cas2,csn2,cas14j,DinG,DEDDh	0	8	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018102_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018102_1

420957-421135

Orphan

Consensus_repeat	Method
CCAAGTAAACCAACAGAACCTGAAAAACCAGTAACACCAACAGAACC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP018102_1

>merge|NZ_CP018102|1|420957-421135|PILER-CR
AACACCAACAGAACCTACAACTCCTACAGAGCCAAGTGAACCAGAACAACCAACGGAGCCAAGTAAACCAGTAGAACCTGAAAAACCAGTTACACCAAGCAAACCAGCAGAACCCGAAAAACCAGTTACACCAAGTAAACCAACAGAACCTGAAAAACCAGTACAACCAGCAGAACCAA

>NZ_CP018102|1|1|420957-421135|PILER-CR
AACACCAACAGAACCTACAACTCCTACAGAGCCAAGTGAACCAGAACAACC	AACGGAGCCAAGTAAACCAGTAGAACCTGAAAAACCAGTTA
CACCAAGCAAACCAGCAGAACCCGAAAAACCAGTTACACCAAGTAAACCAA	CAGAACCTGAAAAACCAGTACAACCAGCAGAA
CCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018102.1\|WP_011109450.1\|409602_409698_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_010714280.1\|418590_418947_+\|pheromone-response-system-RNA-binding-regulator-PrgU	unknown	unknown	gnl\|CDD\|286680
NZ_CP018102.1\|WP_002377931.1\|419771_420650_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319758
NZ_CP018102.1\|WP_010710127.1\|414611_418529_+\|LPXTG-anchored-aggregation-substance	unknown	unknown	gnl\|CDD\|369832
NZ_CP018102.1\|WP_002360797.1\|423478_423847_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239248
NZ_CP018102.1\|WP_002358446.1\|409687_410857_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP018102.1\|WP_002355366.1\|410900_411131_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP018102.1\|WP_071981424.1\|422829_423447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_002358448.1\|411986_412232_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378900
NZ_CP018102.1\|WP_002364326.1\|418968_419355_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_002370667.1\|419500_419761_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_002360793.1\|425177_425453_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_071981425.1\|427013_429506_+\|type-VI-secretion-protein	unknown	unknown	gnl\|CDD\|315512
NZ_CP018102.1\|WP_002365911.1\|426450_426909_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180915
NZ_CP018102.1\|WP_071981423.1\|421555_422827_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236304
NZ_CP018102.1\|WP_002385553.1\|424153_425188_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372237
NZ_CP018102.1\|WP_002377938.1\|425873_426356_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_002358449.1\|412225_412627_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP018102.1\|WP_002387948.1\|425449_425842_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372239
NZ_CP018102.1\|WP_002360796.1\|423846_424161_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP018102.1\|WP_002358449.1\|412225_412627_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.0847e-09
NZ_CP018102.1\|WP_002377931.1\|419771_420650_+\|hypothetical-protein	gnl\|CDD\|319758	cd16427, TraM-like, C-terminal domain of transfer protein TraM. This family contains the C-terminal domain of transfer protein TraM of the G+ broad host range Enterococcus conjugative plasmid pIP501 and similar proteins. The protein localizes to the cell envelope and is part of the plasmid transfer system that is accessible from outside of the cell. TraM displays a fold similar to the type IV secretion system (T4SS) VirB8 proteins from A. tumefaciens and B. suis (G-) and to the transfer protein TcpC from C. perfringens plasmid pCW3 (G+), reinforcing the prediction that TraM performs a key role in the secretion process, which is underlined by its surface accessibility. It is also structurally related to members of the nuclear transport factor-2 (NTF-2)-like superfamily with a high similarity to the NTF-2 protein from Rattus norvegicus. TraM (categorized as T4SS VirB8-like class GAMMA) does not possess the binding pocket of classic VirB8 class ALPHA proteins, recognized by VirB8 interaction inhibitors.	5.94235e-23
NZ_CP018102.1\|WP_010710127.1\|414611_418529_+\|LPXTG-anchored-aggregation-substance	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	9.14751e-73
NZ_CP018102.1\|WP_002358446.1\|409687_410857_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.22717e-38
NZ_CP018102.1\|WP_002360797.1\|423478_423847_+\|hypothetical-protein	gnl\|CDD\|239248	cd02950, TxlA, TRX-like protein A (TxlA) family; TxlA was originally isolated from the cyanobacterium Synechococcus. It is found only in oxygenic photosynthetic organisms. TRX is a small enzyme that participate in redox reactions, via the reversible oxidation of an active site dithiol present in a CXXC motif. Disruption of the txlA gene suggests that the protein is involved in the redox regulation of the structure and function of photosynthetic apparatus. The plant homolog (designated as HCF164) is localized in the chloroplast and is involved in the assembly of the cytochrome b6f complex, which takes a central position in photosynthetic electron transport.	1.8799e-05
NZ_CP018102.1\|WP_002385553.1\|424153_425188_+\|conjugal-transfer-protein	gnl\|CDD\|372237	pfam12642, TpcC, Conjugative transposon protein TcpC. This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.	1.43273e-35
NZ_CP018102.1\|WP_002387948.1\|425449_425842_+\|conjugal-transfer-protein	gnl\|CDD\|372239	pfam12648, TcpE, TcpE family. This family of proteins includes TcpE a conjugative transposon membrane protein.This family of proteins is found in bacteria. Proteins in this family are typically between 122 and 168 amino acids in length.	1.90409e-17
NZ_CP018102.1\|WP_010714280.1\|418590_418947_+\|pheromone-response-system-RNA-binding-regulator-PrgU	gnl\|CDD\|286680	pfam09627, PrgU, PrgU-like protein. This hypothetical protein of 125 residues is expressed in bacteria but is thought to be plasmid in origin. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. It may be involved in pheromone-inducible conjugation.	9.58503e-63
NZ_CP018102.1\|WP_071981425.1\|427013_429506_+\|type-VI-secretion-protein	gnl\|CDD\|315512	pfam12846, AAA_10, AAA-like domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	9.95301e-142
NZ_CP018102.1\|WP_002365911.1\|426450_426909_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|180915	PRK07275, PRK07275, single-stranded DNA-binding protein; Provisional.	4.74503e-64
NZ_CP018102.1\|WP_002355366.1\|410900_411131_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.56714e-07
NZ_CP018102.1\|WP_071981423.1\|421555_422827_+\|CHAP-domain-containing-protein	gnl\|CDD\|236304	PRK08581, PRK08581, amidase domain-containing protein.	9.67392e-34
NZ_CP018102.1\|WP_002358448.1\|411986_412232_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378900	pfam12645, HTH_16, Helix-turn-helix domain. This domain appears to be a helix-turn-helix domain suggesting that this might be a transcriptional regulatory protein. Some members of this family are annotated as conjugative transposon domains.	8.15516e-20

>NZ_CP018102.1|WP_002377931.1|419771_420650_+|hypothetical-protein
MYISFDLEATQAEKIALPVHQRFSLVQGLLLLEQANQEVLATKQGGTIAYFLYTGKEQELPILEAELLLPVKQKDMLDVLLEPVTNDPTLDPIEVKNFLQLVNQSLPKKQRAKSNKKGTEKKETTDTKPVKKKFFLSVSLITLVGLILLMSGFLLGKTNSTPYQEKELEVKKELNTLTEQVNDQNKVETFTRFFLTNYYSGKTDAKTRQAVLKKFVKKEILSDFLSEKSRARSMFPWEVKKKDKQWTIVFIVVLINEKAEQSTKKITFTAEETKEQLVVMERPTEEDFELTN
>NZ_CP018102.1|WP_002370667.1|419500_419761_+|hypothetical-protein
MIILSGLFILGIGIVGGYQLATLPKLIEMKQHKAIQNHFNVKGNEYTYYQEDSENYILSLEDTEYRIKFSKNTPLKVVFTEILEPM
>NZ_CP018102.1|WP_002364326.1|418968_419355_+|hypothetical-protein
MYVSFVLSCLLGFSAYSLLNRLNSLEFVDVWLDKETQKITLKRCFYDTSFKKQTLKELERVYFQLKEIINVQINKRSLNTNDIRNVRELEEKQQEIKRFMLDVLEDAYWKELANMPEDQRHLDDWDFF
>NZ_CP018102.1|WP_010714280.1|418590_418947_+|pheromone-response-system-RNA-binding-regulator-PrgU
MEAVVVEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIYVKPNLGRINVPVFFIKTPINRGVFEEIFGETLKA
>NZ_CP018102.1|WP_010710127.1|414611_418529_+|LPXTG-anchored-aggregation-substance
MKQQMKAKKQYKTYKAKNHWVTVPILFLSVLGAVGLATDNVQAAELDTQPETTTVQPNNPDLQSEKETPKTAVSEEATVQKDTTSQPTKVEEVAPENKGTEQSSATPNDTTNAQQPTVGAEKSAQEQPVVSPETTNEPLGQPTEVAPAENEVNKSTSIPKEFETPDVDKAVDEVKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAKNKAEKERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMGGKVTGNFQNSFVKEANLGSNGGYAVLLEKNKPVTVTYTGLNASYLGRKITKAEFVYELQSSPSQSGTLNAVFSNDPIITAFIGTNRVNGKDVKTRLTIKFFDASGKEVLPDKDSPFAYALSSLNSSLTNKGGHAEFVSDFGANNAFKYINGSYVKKQADGKFYSPEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLANGRISFSFGMTTKGKSNVPVSSAQWFAFSTNLNAQSVKPIFNYGNPKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNVNDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQGIRDTFDAEKVTIDLSKVKVYQADASLNEKDSKAVAAAINSGRAKDVTASYDLHLDQNTVTAMMKTNADGSIVLAMGYKYLLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPGSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERPANYGGITKEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNKVGKQAWSVYLEVERIKTGDVENTQTENYNKELMRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLKGYDKDFAFDTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAHGGQELRVTLPTKVKADVSGDIYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEYAGVVEEWSISDKLDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFEQGVVKITASQAFLDAMNLKENKNVAHSWKAFIGVERIAAGDVYNTIEESFNNETIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVEPELPQTGEKQNVLLTVAGSLAAMLGLAGLGFKRRKETK
>NZ_CP018102.1|WP_002358449.1|412225_412627_-|sigma-70-family-RNA-polymerase-sigma-factor
MQQNYNEKSIQHQFDAYCKKVLRNEITSIRKRNTNIKYNEEPLTDSTEGKYSQTHFDEQDVYFLFGMEILISDQKLSTAIDHLSEIRRKVILLYYFAGFNNTEIGKILNMSTSGIWYQRKKAVEQLKTEYDLW
>NZ_CP018102.1|WP_002358448.1|411986_412232_-|helix-turn-helix-domain-containing-protein
MVDNKKKRQYPLVPLSVIQSALEEDPISIKMILKHYHSYIVKLCLTNGFNEAEQFITYVDEYMLRQLEIKLIEAILKFKIN
>NZ_CP018102.1|WP_002355366.1|410900_411131_-|helix-turn-helix-domain-containing-protein
MDFQDYEKIFESYPSILKITDLTKMLNIGKNKAYNLLKDKSIENIKIGARYKIPKKAVIEYILKIQDEGKNHAIIE
>NZ_CP018102.1|WP_002358446.1|409687_410857_-|site-specific-integrase
MKLRANIIEKRGTLQVIVSYKDSNGKIRQKWKDTKLKKKGNKKRAEKIRDEFLLELESQLAMECECANPDLLFYDYLLNYLEVSKKQVAFNTYVGYKHYVHNRIYKFFYPKKIKLNRLKPYHLQDFYQYMLNDDCTANTVIHYHAFIRKALQEAVITELISTNVADKVRKPKKKQFVSQVYNQHEILKLLDILSEEKLYLVVLLTAFYGLRRSEVLGLKWSAIDFLNKKIMINHVIIENPENMSQLIKKDQTKNSSSYRTLPLVETIERALVNQAKWQQDNRILLGEDYILKDSEYVFTMEDGRLMKPQYVTHRLSKLIKKNGLKKIRFHDLRHSNASIMLDSGQNMKSIQEWLGHASYSTTANLYTHLTAGVKERAAEALENAFGFKE
>NZ_CP018102.1|WP_011109450.1|409602_409698_+|hypothetical-protein
MPTYWQQIANEKNSKNKKRYHEDIVFLFFIL
>NZ_CP018102.1|WP_071981423.1|421555_422827_+|CHAP-domain-containing-protein
MNKKRIVFGLLSFFLPIFLVFGGLLFFLLLLTSTSDTSKNDCIQPSINNPTDATDTPKSIEQFVKSHKDAYLLSWKAGGFLPSASISQTMVENGFNFTNPSGTSFWQAHNMGGVKTSKKEDFPVTLATFGQDSVDISGTKPGSNVGDGTGGAYTWFKDYNAGIVGKAEFMAHQTLYTGAINNTDGLSTLSAIYSGGWATDPTYLMKLQATYNSLGKQFQWLDQEAIQKYGNAPFKKSELVPNIPGKSPITNEKSGKNSDCVVTSDISDQVTGQNTAPSLEVPSAYKGKLTLPPIDSNDYAGNNYPFGQCTWYAYNRMAQIGKPIEWFAGDGGNGAGWANSARAKGYTVVKGKPSVGWAASMQGGIGGSAPPYGHVAVVEYVNSDGSILVSEANVINQGSGTRSWRVLDRATVEQIDFIQGKGA
>NZ_CP018102.1|WP_071981424.1|422829_423447_+|hypothetical-protein
MRERLKQAQPLVIVLLLVLLTTLGGGYFNEKKENAQIKNQKEKEQQVLKKTLEEKNGQLNDLSRKIEQLLDEKEDPVNESLTKAVNGLFSLVFDYDSSNKEQTVAKRKEKATVYATEQGLSGVFPRDADKVVPSVVTVSQLDKAPEIYRTTQKDTGKEKTALVRLEYSVRIAGSQAQRGNFIYKVTFNEESKKFTTIENLGEENQ
>NZ_CP018102.1|WP_002360797.1|423478_423847_+|hypothetical-protein
MLVLGGISLFLFMVKQNEKAMLNQEKERAAVVLADNETRVLFFYKDTCADCQKVYPTVYEEDQGENNIVFINLNQPKNRHYIKTYTLEKVPTFVTPKRRYVGTDTRKIQQLIAENNDERSED
>NZ_CP018102.1|WP_002360796.1|423846_424161_+|hypothetical-protein
MHENHVNEKETAVENTERIAKNYAYERPAIQTALFILWRVHNKQYQTGARIFYDELEKATKTSKTAYKEALAFLEGAGMVVNEVVVESKVPQSLIQRYGILKDE
>NZ_CP018102.1|WP_002385553.1|424153_425188_+|conjugal-transfer-protein
MSNKKAVFNPQAGKQAQKEKVRKETRVSSLVQIIRAIFRKKEKEPENSRTIRFSPRSAKSIYSMVFFLLFFLISLFLLMSFGRLNTLTRLAMQKQVNREEIIESVNKGVAASDQLKYDGMKLVDRLFTVSSKLEGKEYWEAQITPYLAAGLRAEDLGLDKTNDDRVARNVRFIRLETVDYKESLYSLYYDVRFTEGKEWRQVQVILPVSYAENELKLLDRPTLMNLAKTSESNKVAYDEQRFIPKGKEVNEEETKKLTEFTNRFFELYVKNDEKLGLIANVKGLEHATLEKVDITSLRETGQGVYDVRGTYQFSYEGKSPLTSNFSLQIEATKDSYFIKKMNGV
>NZ_CP018102.1|WP_002360793.1|425177_425453_+|hypothetical-protein
MECKNMFDLSGLANNISSQVIILLVILGLVSLVVAVATQGAARGIATVCLILILIALVLVLKDAEKIGTWLKDLIFKPNAGFIFPIKGWRF
>NZ_CP018102.1|WP_002387948.1|425449_425842_+|conjugal-transfer-protein
MMEYNYTREFKQPHKIYSIKGVALPFAPNGIRLEQIFVGIGILILLLIFAIISFVAKINFFTTIIANFWLILIVGVGVLVWTLFSLKWDNKSFLDYLIGRGNFLYQKKKRYEHGLLVQFHKEKVQYKVRK
>NZ_CP018102.1|WP_002377938.1|425873_426356_+|hypothetical-protein
MKVDKRIEAVTKFLESLGTVEDYTEDVAVKYRNLILKSYELYENKYNDTVDDSLCIEVWSNGTYVVTNEDLSFDCESEEDLQKLKELFVNTSFYITINELNKVGHKATLSVKAKAKNLRKLGQLIKEYRSCNCKYLKDKVTEIIGDDGRVYLDRISERMD
>NZ_CP018102.1|WP_002365911.1|426450_426909_+|single-stranded-DNA-binding-protein
MINNVTLVGRLTKDPDLRYTQSGTAVGQFTLAINRNFTNANNEREADFINCVIWRKAAESLANYATKGTLIGLTGRIQTRNYENQQGQRIYVTEVVTESFQLLESREVNEQRKEQATGKATFDKQSMDKPDPLDPFSPENSIVDISDNDLPF
>NZ_CP018102.1|WP_071981425.1|427013_429506_+|type-VI-secretion-protein
MPLKSKEPRLDFPIEAITNNFLFTTSNDVWVGYKLAHQVFPLNNLDFFKEYIEDGKGVFEQDTFDYHFMNIPEYFDLDEQIEATIDNLVKGSFADLGETYFRQAGDILKDEVQMNKYSTYLFIRFTAPIQVANPMEYIELFKEVGRKAINALTGVHVPVSQLYRAYQGLENKIYKDLSNFKNVERMDPRTIGRLFYYFFHRANTRLPERTLLPEEMTEGIIENNTGYMTIEQLDKTHYLAFLPLISLPTSMFGSAIIQNLQDSLSTTIETHVKVTFRHPDKDKRDVHKRRKRIYEQDKEQTQVDGILDEDEVILFGEERLHELSKKIRSKERRLCRMTTTFVLSADSKQALEEKIKELEFVLDGTDYKLYRPLVDQLTLFNQCLIGAKSQFKSYEHVVSTGYVADLGMDLEKEIGNRYGMPLGRVITAKKFKSVQQALSLSSKIVWFFPNLTKKAIEGAQYTNGNTLIIGPPGQGKSVLVKYIFLWLTFLGQKILYIDLKNETVLFFKRALDKFGHIPEFKALYQRINFVSLSSEERYRGMLDPLLFLPREEAIQTARNVLENFGEVTTDSHTASDKKTLILDSVNAVMKGKGKKHLTKVIEVIREKDPKLANLISGHNVGLGKILLGNDYSEPIRFENQINVLGTQGLKIPTQAEIDSGRLNNEQIAGMSIMEVIMKMTTIFSTDKTEDAAIIFDEAKGFEDTAQGRFLIEGSLRQGRANMTDIYLVTQAFMDYDKEDKKELLSYKFAFRPNQKEAQKKVLEFFGMDTNPANIQLINELKSGTCLFQDHRGRSQPIAIDVLFDSWLMAVSSTNKEDEATQMALAMEQGS

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Crispr_ID: NZ_CP018102_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018102_2

489163-489794

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CRISPRCasFinder
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	PILER-CR

9 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP018102_2

>merge|NZ_CP018102|2|489163-489794|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACACTGCTCATTCGTTTTCTCCTCCTAACACGCTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACCAGCGCCGGAAAAGTAGCAAGCCCCACAGTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACACGTGCCTTCAAATCCAAAAAAGGTTTGTTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTGTTTTAAATTCATACATAACGAAACATGTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTTAGAAAAGACGTGACAGAGCAAACAGCGCGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACAGGTACAATTTATGGATTGTCACATGTCATGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTGATGAAAACCGATGGTATTTACTTTCACAGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACCTCGTTAGAATGCCCTTCACAGCTGTTAAAGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATCTCTAATGAGCATTCATTACATATGTAGAACGTTTTAGAGTCATGTTGTTTAGTTTTCGCAAATACG

>NZ_CP018102|2|2|489163-489530|PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACTGCTCATTCGTTTTCTCCTCCTAACACGCT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CAGCGCCGGAAAAGTAGCAAGCCCCACAGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACGTGCCTTCAAATCCAAAAAAGGTTTGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGTTTTAAATTCATACATAACGAAACATGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TTAGAAAAGACGTGACAGAGCAAACAGCGC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACAGGTACAATTTATGGATTGTCACATGTCATGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGATGAAAACCGATGGTATTTACTTTCACA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTCGTTAGAATGCCCTTCACAGCTGTTAAA


>NZ_CP018102|2|1|489163-489794|CRISPRCasFinder
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACTGCTCATTCGTTTTCTCCTCCTAACACGCT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CAGCGCCGGAAAAGTAGCAAGCCCCACAGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACGTGCCTTCAAATCCAAAAAAGGTTTGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGTTTTAAATTCATACATAACGAAACATGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TTAGAAAAGACGTGACAGAGCAAACAGCGC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	AGGTACAATTTATGGATTGTCACATGTCAT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGATGAAAACCGATGGTATTTACTTTCACA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTCGTTAGAATGCCCTTCACAGCTGTTAAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATC	TCTAATGAGCATTCATTACATATGTAGAAC
GTTTTAGAGTCATGTTGTTTAGTTTTCGCAAATACG

>NZ_CP018102|2|1|489163-489794|CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACTGCTCATTCGTTTTCTCCTCCTAACACGCT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CAGCGCCGGAAAAGTAGCAAGCCCCACAGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACGTGCCTTCAAATCCAAAAAAGGTTTGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGTTTTAAATTCATACATAACGAAACATGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TTAGAAAAGACGTGACAGAGCAAACAGCGC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	AGGTACAATTTATGGATTGTCACATGTCAT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGATGAAAACCGATGGTATTTACTTTCACA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTCGTTAGAATGCCCTTCACAGCTGTTAAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATC	TCTAATGAGCATTCATTACATATGTAGAAC
GTTTTAGAGTCATGTTGTTTAGTTTTCGCAAATACG

>NZ_CP018102|2|3|489561-489728|PILER-CR
	ACTGCTCATTCGTTTTCTCCTCCTAACACGCT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CAGCGCCGGAAAAGTAGCAAGCCCCACAGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACGTGCCTTCAAATCCAAAAAAGGTTTGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGTTTTAAATTCATACATAACGAAACATGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TTAGAAAAGACGTGACAGAGCAAACAGCGC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACAGGTACAATTTATGGATTGTCACATGTCATGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGATGAAAACCGATGGTATTTACTTTCACA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTCGTTAGAATGCCCTTCACAGCTGTTAAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018102.1\|WP_002358655.1\|480937_482353_+\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|130941
NZ_CP018102.1\|WP_002358653.1\|475942_476515_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223477
NZ_CP018102.1\|WP_002378005.1\|476581_478108_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	unknown	unknown	gnl\|CDD\|237588
NZ_CP018102.1\|WP_002355509.1\|494436_494892_+\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_CP018102.1\|WP_002378009.1\|483202_487216_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP018102.1\|WP_002367997.1\|496456_497011_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP018102.1\|WP_002355504.1\|482496_482730_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_002378021.1\|501085_502321_+\|DNA-repair-exonuclease	unknown	unknown	gnl\|CDD\|277319
NZ_CP018102.1\|WP_002355518.1\|500588_500930_+\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|237467
NZ_CP018102.1\|WP_002378020.1\|498339_500526_+\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_CP018102.1\|WP_002364834.1\|487216_488083_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP018102.1\|WP_002381241.1\|490574_491588_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122
NZ_CP018102.1\|WP_002378012.1\|488409_489069_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP018102.1\|WP_002378016.1\|492777_494295_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_CP018102.1\|WP_002364837.1\|478311_479961_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_CP018102.1\|WP_002395370.1\|480030_480804_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP018102.1\|WP_002401855.1\|494925_496446_+\|phosphoglucomutase	unknown	unknown	gnl\|CDD\|215211
NZ_CP018102.1\|WP_002401854.1\|497134_497986_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP018102.1\|WP_002364833.1\|488079_488409_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP018102.1\|WP_002367993.1\|491823_492777_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050

Protein	Function_ID	Function_description	E-value
NZ_CP018102.1\|WP_002358655.1\|480937_482353_+\|dipeptidase-PepV	gnl\|CDD\|130941	TIGR01886, Beta-Ala-Xaa_dipeptidase, dipeptidase PepV. This model represents a small clade of dipeptidase enzymes which are members of the larger M25 subfamily of metalloproteases. Two characterized enzymes are included in the seed. One, from Lactococcus lactis has been shown to act on a wide range of dipeptides, but not larger peptides. The enzyme from Lactobacillus delbrueckii was originally characterized as a Xaa-His dipeptidase, specifically a carnosinase (beta-Ala-His) by complementation of an E. coli mutant. Further study, including the crystallization of the enzyme, has shown it to also be a non-specific dipeptidase. This group also includes enzymes from Streptococcus and Enterococcus. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP018102.1\|WP_002358653.1\|475942_476515_+\|hypothetical-protein	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	4.15912e-18
NZ_CP018102.1\|WP_002378005.1\|476581_478108_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	gnl\|CDD\|237588	PRK14022, PRK14022, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase.	0
NZ_CP018102.1\|WP_002355509.1\|494436_494892_+\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	1.0984e-46
NZ_CP018102.1\|WP_002378009.1\|483202_487216_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP018102.1\|WP_002367997.1\|496456_497011_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	5.36986e-26
NZ_CP018102.1\|WP_002378021.1\|501085_502321_+\|DNA-repair-exonuclease	gnl\|CDD\|277319	cd00840, MPP_Mre11_N, Mre11 nuclease, N-terminal metallophosphatase domain. Mre11 (also known as SbcD in Escherichia coli) is a subunit of the MRX protein complex. This complex includes: Mre11, Rad50, and Xrs2/Nbs1, and plays a vital role in several nuclear processes including DNA double-strand break repair, telomere length maintenance, cell cycle checkpoint control, and meiotic recombination, in eukaryotes. During double-strand break repair, the MRX complex is required to hold the two ends of a broken chromosome together. In vitro studies show that Mre11 has 3'-5' exonuclease activity on dsDNA templates and endonuclease activity on dsDNA and ssDNA templates. In addition to the N-terminal phosphatase domain, the eukaryotic MRE11 members of this family have a C-terminal DNA binding domain (not included in this alignment model). MRE11-like proteins are found in prokaryotes and archaea was well as in eukaryotes. Mre11 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	9.16125e-50
NZ_CP018102.1\|WP_002355518.1\|500588_500930_+\|YlbF-family-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	2.56028e-37
NZ_CP018102.1\|WP_002378020.1\|498339_500526_+\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP018102.1\|WP_002364834.1\|487216_488083_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.59266e-115
NZ_CP018102.1\|WP_002381241.1\|490574_491588_-\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	2.63008e-11
NZ_CP018102.1\|WP_002378012.1\|488409_489069_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.59659e-118
NZ_CP018102.1\|WP_002378016.1\|492777_494295_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.15846e-168
NZ_CP018102.1\|WP_002364837.1\|478311_479961_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.27874e-136
NZ_CP018102.1\|WP_002395370.1\|480030_480804_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	5.74514e-92
NZ_CP018102.1\|WP_002401855.1\|494925_496446_+\|phosphoglucomutase	gnl\|CDD\|215211	PLN02371, PLN02371, phosphoglucosamine mutase family protein.	0
NZ_CP018102.1\|WP_002401854.1\|497134_497986_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.48238e-91
NZ_CP018102.1\|WP_002364833.1\|488079_488409_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.08189e-44
NZ_CP018102.1\|WP_002367993.1\|491823_492777_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.78143e-140

>NZ_CP018102.1|WP_002378012.1|488409_489069_+|type-II-A-CRISPR-associated-protein-Csn2
MRVNFSLLEEPIEIEKATFLTIKDVQTFAHLVKLIYQYDGENDLKLFDAQQKGLKPTELFVVTDILGYDVNSAATLKLIYGDLEAQLNDKPEVKSMIEKLTGTISQLIGYELLEHEMDLEEDGITVQELFKALGIKIETTSDTIFEKVMEITQVHRYLSKKKLLIFINACTYLTEDEVQQVVEYISLNNVDVLFLEQRVVQNRFQYILDENFYLSYEKA
>NZ_CP018102.1|WP_002364833.1|488079_488409_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRLLLMFDMPTDTASDRKAYRKFRKFLINEGFIMHQFSVYSKILLNDTANKAMLARLKQNNPQRGLITLLNVTEKQFSRMIYLHGEQDNRVANSDERIVFLGEE
>NZ_CP018102.1|WP_002364834.1|487216_488083_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNKHSKLSYKNNHLVFKAIDHQELIHLSEIDVLLLETTDISLTTMLLKRLIDEKILVLFCDDKRLPIGKILPFYGRHDSSLQLTRQLAWTEERKGQVWTAIIAQKITNQSLHLAQRDYGQKAAALLAMRAELRLFDPANREGHAARSYFNTLFGNDFTREQENDINAGLNYGYTLLLSIFARELVQTGCFTQLGLKHANQFNDFNLASDLMEPFRPLVDQIIYENRKEAFPIMKRKLFALFMNTYMYKKKQMFLTNIATDYTKHVVKVLNQEEEGVPEFGI
>NZ_CP018102.1|WP_002378009.1|483202_487216_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKDYVIGLDIGTNSVGWAVMTEDYQLVKKKMPIYGNTEKKKIKKNFWGVRLFEEGHTAEDRRLKRTARRRISRRRNRLRYLQAFFEEAMTALDENFFARLQESFLVPEDKKWHRHPIFAKLEDEVAYHETYPTIYHLRKKLADSSEQADLRLIYLALAHIVKYRGHFLIEGKLSTENISVKEQFQQFMIIYNQTFVNGESRLVSAPLPESVLIEEELTEKASRTKKSEKVLQQFPQEKANGLFGQFLKLMVGNKADFKKVFGLEEEAKITYASESYEEDLEGILAKVGDEYSDVFLAAKNVYDAVELSTILADSDKKSHAKLSSSMIVRFTEHQEDLKNFKRFIRENCPDEYDNLFKNEQKDGYAGYITHAGKVSQLKFYQYVKKIIQDIAGAEYFLEKIAQENFLRKQRTFDNGVIPHQIHLAELQAIIHRQAAYYPFLKENQEKIEQLVTFRIPYYVGPLSKGDANTFAWLKRQSEEPIRPWNLQETVDLDQSATAFIERMTNFDTYLPSEKVLPKHSLLYEKFMVFNELTKISYTDDRGIKANFSGKEKEKIFDYLFKTRRKVKKKDIIQFYRNEYNTEIVTLSGLEEDQFNASFSTYQDLLKCGLTRAELDHPDNAEKLEDIIKILTIFEDRQRIRTQLSTFKGQFSAEVLKKLERKHYTGWGRLSKKLINGIYDKESGKTILDYLIKDDGVSKHYNRNFMQLINDSQLSFKNAIQKAQSSEHEETLSETVNELAGSPAIKKGIYQSLKIVDELVAIMGYAPKRIVVEMARENQTTSTGKRRSIQRLKIVEKAMAEIGSNLLKEQPTTNEQLRDTRLFLYYMQNGKDMYTGDELSLHRLSHYDIDHIIPQSFMKDDSLDNLVLVGSTENRGKSDDVPSKEVVKDMKAYWEKLYAAGLISQRKFQRLTKGEQGGLTLEDKAHFIQRQLVETRQITKNVAGILDQRYNAKSKEKKVQIITLKASLTSQFRSIFGLYKVREVNDYHHGQDAYLNCVVATTLLKVYPNLAPEFVYGEYPKFQTFKENKATAKAIIYTNLLRFFTEDEPRFTKDGEILWSNSYLKTIKKELNYHQMNIVKKVEVQKGGFSKESIKPKGPSNKLIPVKNGLDPQKYGGFDSPIVAYTVLFTHEKGKKPLIKQEILGITIMEKTRFEQNPILFLEEKGFLRPRVLMKLPKYTLYQFPEGRRRLLASAKEAQKGNQMVLPEHLLTLLYHAKQCLLPNQSESLAYVEQHQPEFQEILERVVDFAEVHTLAKSKVQQIVKLFEANQTADVKEIAASFIQLMQFNAMGAPSTFKFFQKDIERARYTSIKEIFDATIIYQSTTGLYETRRKVVD
>NZ_CP018102.1|WP_002355504.1|482496_482730_+|hypothetical-protein
MSETLIVNYLIKGRVKMNVEELVQKAKDLIGEGNVEHAQQFIEEHKDELGEHYHKITAMLADTTTDGLFDKIKGLFQ
>NZ_CP018102.1|WP_002358655.1|480937_482353_+|dipeptidase-PepV
MTIDWTKEVEARKDDLLEDLQNLLRINSERDDAQATPEAPFGPGPVAGLKHMLAYGERDGFTVKNVDNYAGHIEYGEGDETLGIFGHMDVVPAGDGWETDPYEPVIKDGKIYARGASDDKGPSMAAYYAMKIIKELGLPVSKKIRFVVGSDEESGWGDMDYYFQHEEAPDFGFSPDAEFPIINGEKGNVTIRLTFRGGNGADYKLESFKSGLRENMVPGTADAVVTAASADEAASLAASFETFIKQEAKISGNAELSDKTVTFHVVGKGAHGASPQSGINAATFLATFLNDYSFAEGAYSFINTIAEFIHEDFYGEKLGVAFEDEKMGKLTMNAGIVNFDPENPENSLVTLNFRYPKGTSAEELQAKVQATVGETVTATQGDRNQEPHYVPVDDPLVATLLQVYEDHTGEKGQEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEFMELDDLFRAAAIYADAIYRLAK
>NZ_CP018102.1|WP_002395370.1|480030_480804_+|rRNA-pseudouridine-synthase
MSQAIFLKERGMTMRLDKFLADVGIGSRKEIKQLLKKKVVTVNGDVVKEAKTQVNEETDQIALMGEILTYQKFFYYMLHKPQGVISATEDQRDETVIDLLTDQDYRADLFPVGRLDKDTEGLLLLTNDGQLAHQLLSPKKHVDKEYLAEVEGLVTAEDCQLFAQGFALKDGEMVKPSRLVIETINEEEGTSVVRLVIQEGKFHQVKRMLATVGKPVTYLKRLRMGELWLDETLELGGYRPLTEAELQQLQPKQSYLN
>NZ_CP018102.1|WP_002364837.1|478311_479961_+|polysaccharide-biosynthesis-protein
MINQPNSVDQPILTNQEKMVKGSAWMTASNIISRMLGAIYIIPWYAWMGEHGNEANSLFSMGYTIYALFLMISTAGIPGAIAKQTSHYNSLNEYKISRQLFYRALQLMGGLGVVFAIVMYLASPALAALSGGGPELVPTMRSLSLAVLVFPSMSVIRGYFQGNQEMMPFALSQIVEQVARVFYMLLTAFIIMKVFEGNYVTAVTQATFAAFIGMLASFAVLGYYMYKQKPLFDYLEEHSANEHEIAPKELLIETFKEAIPFIVVGSGVTVFKLVDQFTFSNFMRLFTDYSDTQLRELFGIFNANPDKLTMIVVALATSISATGLPLITEAVTLKNHRELARLISNNLQLFVFVMLPATFGMIVLAQPLYTVFYMPDALGTSLLVQACYASLFLGLYMLVSNMLMGMYENRDAMRYLGIGLAVKLIVQFPAIRLFEVYGPLLATMIGFTVSCVLILRRIRQVTRFNYKLTLRRTLLMFCITVIMMIIALIFRQFLYLFLDPTRRFQAFIIVVIVAAAGGAFYGYSVLKIRLADRLLGKNAAKLRAKFNIK
>NZ_CP018102.1|WP_002378005.1|476581_478108_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase
MTISLFAIRDCLEKEDLLKEFISPEGWHLTLSDTLGQREVTALSYDSRDVTAETLFFCKGLNFKEIYLENAVKDGLEIYVSEVPYEVPAQLGIIVTDIKKAMAVLSMAFYDYPQNKLKLIGFTGTKGKTTAAYFTKYILDVATQQKTALLSTMNSTLDGKTFFKSALTTPESLDLYRMMATAVANGMTHFIMEVSSQAYKTNRVYKLFFDVGIFLNITPDHISPIEHPTFDDYFYCKRQLITHSKVIVLNHEADYFPLLKETAQQQKVPAIVYGSQPAPEVDYSFAVSSEDSLRFIVESPADALGLAGSYHLRLGGDFNKGNALSAAIASVLVGASKEECQQGIAATTVPGRMESLTNTNGATVYVDYAHNYDSLKNLLTFVREEHPDGRLIVLVGSTGDKAISRRKDFGRVLSELADVAVLTTDDPASEDPAKICQEIQAHITKEMPVYTILDRGEAIAHALSLSTTADDAIVLAGKGADLYQKVNGVDEPYAGDFALAEAFINKKN
>NZ_CP018102.1|WP_002358653.1|475942_476515_+|hypothetical-protein
MKQFFQKGSKPNQLVVAFHGTGGNEYQLLTTIATLYPEASVLSYLGTEGVGEQRRFFAPLVNGALPRANFDERVTAFLEEVWQPQKLYDEVIFIGYSNGANFILGLLEKNPTIANTVILLHPSNLGYQYVSGEFATKVIVTTGAQDELSIPGQVLSLANQLKKHFPVDFLLVDGGHGLSEEEVTKIKEVL
>NZ_CP018102.1|WP_002381241.1|490574_491588_-|acyltransferase-family-protein
MENDKRIYKWDNVKLFLIFLVIFGHILDREASPSRLMETINFWIYSFHMPAFIFVSGLFSKHAIKQRKYLRLLSFVWLYLLAKLLITLANFAFANKMNFDLLNETGVPWYLLSLASFYLITIFLQRVQPKIMLPIIIVIGCASGYLPVEGFLSLGRTLGFFPFFYCGYLMDIQKLQTFLDHRKVKWAAIGVILSSFLFVNSQWSLATKFWGFLTGWASYAEISPAFEYSSFIQLFFYVAAALVSLSWFALLPKRKLPLSALGKDTLYPYLLHMPLIILLESGLQLDTLFKEWFTFRILALFFLALFILAITNMPVVKRGADYLFNPQSIMIPKKIYK
>NZ_CP018102.1|WP_002367993.1|491823_492777_+|ABC-transporter-ATP-binding-protein
MIKFQNVSKVYQENAVLSDVNLTIQQGEFFVLVGPSGSGKTTTLKMINRLIEPTTGEVALNEQAVTNYPLRELRLKIGYVLQQIALFPNLTVAENIELIPEMKKWPKEQRRERTIELLKKVQLNPEEYLHRKPAALSGGEQQRIGILRAIAAEPEVILMDEPFSALDPISRHHLQRLVKELHQELASTIVFVTHDMNEALLLGERICIMDAGKIIQVDTPEAIQKHPKNNFVGQFFKQSSPELANYCGADLTAFLEAADETIEPVPTVFMETNLKEIVQLINAQEKANLVEKQQVLGCITSKTITRFMEQLLESEGQ
>NZ_CP018102.1|WP_002378016.1|492777_494295_+|ABC-transporter-permease/substrate-binding-protein
MQALIETFFARKEEYLQALIEHMQLSFISLLFAALIAIPLAIYLTSHRKLAESLLQVTGIFQTIPSLALLGLLIPLIGIGQPPAIVALVIYALFPILQNTYTGLTEIDPSLEEAAEAFGMSKKEKLFKFELQMALPFIISGIRTATVLIIGTATLAALIGAGGLGTFILLGIDRNNLSLIFIGALSSAALAVLFNYGIHWLEKANGRRLIIGGTILGLLLGGSFFWNQQTSSKEKQLTIAGKLGAEPDIIINMYKALIEENSDIQVTLKPNFGKTTFLYNALKSDEIDLYPEFTGTVIETFLKNPPQLDNQPQVVYEAARAGLKKQENLTLLKPMRYENTYAVAVKRSFAKAHQLKTISDLQKISNQLKAGFTLEFIDRQDGYKGLQEKYHLNLNVQSMEPALRYQAINNGEVNVIDAYSTDSELRQYDLVTLEDDQALFPPYQGAPLIKTATLEKYPELAEILNKLAGKISEEEMSEMNYQVNVEGQDPSIVAKDYLKEKNLLK
>NZ_CP018102.1|WP_002355509.1|494436_494892_+|arginine-repressor
MKKAERQRLIKQLIMQQEIETQDELITRLEELGVRATQATVSRDIREMSIVKTHGADGRVKYAIFSQAQGTSSEEKLRESVKDSVVRMERVQFIVILHTEMGNADVVSNFLDEVAYPEVAGTVAGADTIIVITRSEEDAEHFIERIENMIF
>NZ_CP018102.1|WP_002401855.1|494925_496446_+|phosphoglucomutase
MVELKALQNGSDIRGIALDTEEQTATLTATAVAEIAVGVVRWLQDKKQLPRKAQQRLTIAIGHDSRLTAEPIKQALVDTFLSLGIQVIDVGLATTPAMFMATQFPTLQCDAAIMITASHLPYYFNGLKFFTAEGGAEKEDIRYILSHTDPLTANENGTLMKQELLPIYAEHLVAKIRQGIHSPEEKPLQGFRIIVDAGNGAGGFFAEQVLQVLGADTTGSQFLEPDGHFPNHVPNPDNSEAMKSIQTAVLANQADLGIIFDTDVDRSAVVDQSGEVLNRNNLIAVLAAIVLKEAPGSYIVTNSPTSSHLKTFIEEKGGQQIRYISGYRNVINKMIELNHGGFQTPLAIETSGHAAFQENYNLDDGAYVVAKILMLLPELKQNNQTLGDLIATLKQPAETNEFRFKITAEDVTCYGQQVLRDFELFVESQADFAVDRENQEGVRGNVSGQYGSGWFLLRLSLHEPLLVLQVENDQSDKNACVIEKIATFLQKYEEIDSQQIENNLGN
>NZ_CP018102.1|WP_002367997.1|496456_497011_+|GNAT-family-N-acetyltransferase
MENVLKGKHIGFSHFREEYIEHIAKQQWDNELLRHLSWDALHPWGLEEWKDFTINKGEDDRFLFAILENTTEEFIGWVSLSDVQLKNRGANLGIAILQKEQRGQGYGFEAVSLICKFAFYELGLHKIRLAVNSNNQKAIHVYEKVGFKKEGIDREALFQDGQWLDIYNYGILQKEWLQMIKAES
>NZ_CP018102.1|WP_002401854.1|497134_497986_-|RluA-family-pseudouridine-synthase
MRLPENFSTMTVKELLENEWLVPRKVRHFLRTRKNVKINGETAAFHFPVQAGDCVTLTFEETDYVRPTIHLGEATHVKVLYEDEHLMIVNKPYGIKTHPNQPQETDTLLNHVAAYLAEKNQVPYVVHRLDKETSGAIVFAKNPFVLPILGRLLETKQIYRQYQAIVAGHFNQKEQTINQPIGRDRHDRRKRRIDPQKGDSAITHVQVVQALSNNQTAVTCVLETGRTHQIRVHLASEGHPIIGDPLYNPKSQAARLMLHASQLHLLHPFTKKQIVVTAAPGLW
>NZ_CP018102.1|WP_002378020.1|498339_500526_+|PBP1A-family-penicillin-binding-protein
MDNLKQFFSKVGVGLRHFWTWIKPYLIQFHQARKRIWKKYQINKIFLLIGLVVALGASIYLFYLAKSANVETLKSGLSESTRVYDESGEEVGKLFGQKGTFVELDNISPYIQDAVISTEDRGFYQHKGYSIKGIARAVVGKLTFGKIGGGGGGSTITQQLAKNAYLTQEQTLDRKARELFLAIEIEKKYSKKDILAMYLNNSYFGNGVWGVQDAARKYFGVDASQVTVGEAATLAGMLKGPGIYNPIDYIDNATARRNTVLQLMVDNKKLSQEEANQEASVNLASLLNDTYVGDENSYKYPYYFDAVIDEAVNRYKFKEEDILNKGYKIYTSLNQGYQDAMDATYKNDALFPPNAEDGAMVQSGSVAIDPKTGGVQALVGGRGEHVYRGFNFATQTKRSPGSSLKPISVYTPALEAGYKPDSVLEDKPQDYYPAQNYSRTYSGEVPMYQALGESLNLPAVWLLHQIGLDKGYEKTEKFGIPLSEKDRYYGLALGGLQTGVSPLTMAGAYSAFANEGYKTETHLITKIVDSTGAIVVDNTKVKKEQVITKDVADGITSMLLGVFSSGSGVNAQPAGYVMAGKTGTTETNFDSSKTNDQWVIGYTPEVVIATWLGFQETSKTHYLEGSSATYASQVFNSQASGILPQVKQAQFPVADAYATGGKVVDSNDSLTGGANSNWRDNLKDFGNSVQDGASNFGDTLNEVGGQIKDGAKKVKDKIEGIFGGLLGN
>NZ_CP018102.1|WP_002355518.1|500588_500930_+|YlbF-family-regulator
MSNIYDTANQIERELRELDEFKALQAAYEEVKADEAAYTLFKEFQGFQQGLQEKQMRGEEFTDEDAEKAQSIATKVQETAVINELMQKEQAFSLVVNDLNRIIMTPVRDMYND
>NZ_CP018102.1|WP_002378021.1|501085_502321_+|DNA-repair-exonuclease
MKLLHTADLHMDRSFEGLTGIPTALAKRLREANQQLLMNIVTVAIREAVDLVIFAGDTFHQSQTSISMQAQLMAALEQLKQAEIPVILTFGNHDYYKKDRYWFSFPDNVFLFEKEMVETLYFETRAGEQVAVSGFSYEHPWIDENKALEFPIKQADSDIHIGIYHGDTSRKAQQNYAPFTWKDLKATGYNYWALGHIHQPQIVSEQPLIVYPGTPQGHTKKEQSLQGVAVVTLSQNQATVQFEKVAEIDWTNEEVSLAQCRDTQSVLSYLETSLLTKWHAHQQQQLMALTLKETQHLDVTVVQAIVNGELLSYLQQQLLQKTQGDFFVYRLILQAEEPTKEPIYLSASPNLLTALEKTYLDPVIFEDTTKELLRYPEFAGIFSMDEQWRSESLRLAHEQINEDFTIQEDPL

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Crispr_ID: NZ_CP018102_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018102_3

1923119-1923232

Orphan

Consensus_repeat	Method
ACAACGTTCCCTTTGGTCACCTTGTACTGTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018102_3

>merge|NZ_CP018102|3|1923119-1923232|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTACTGTTCATCATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAGACAACGTTCCCTTTGGTCACCTTGTGCTGTTC

>NZ_CP018102|3|2|1923119-1923232|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTACTGTTC	ATCATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAG
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018102.1\|WP_002389231.1\|1928554_1929529_-\|phosphate-starvation-inducible-protein-PhoH	unknown	unknown	gnl\|CDD\|224616
NZ_CP018102.1\|WP_010715369.1\|1918268_1918544_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|224174
NZ_CP018102.1\|WP_002356744.1\|1926327_1928526_-\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397
NZ_CP018102.1\|WP_002382766.1\|1919676_1919868_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_CP018102.1\|WP_002382768.1\|1918710_1919643_+\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
NZ_CP018102.1\|WP_002356740.1\|1930186_1930363_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP018102.1\|WP_002356746.1\|1925463_1925871_-\|diacylglycerol-kinase-family-protein	unknown	unknown	gnl\|CDD\|260134
NZ_CP018102.1\|WP_002382772.1\|1916928_1917366_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CP018102.1\|WP_002382765.1\|1923670_1924465_-\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
NZ_CP018102.1\|WP_071981528.1\|1917385_1918162_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
NZ_CP018102.1\|WP_071981529.1\|1919907_1921992_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NZ_CP018102.1\|WP_002356745.1\|1925848_1926328_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NZ_CP018102.1\|WP_002356736.1\|1930528_1930963_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NZ_CP018102.1\|WP_101731707.1\|1923318_1923402_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_002356759.1\|1915959_1916745_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP018102.1\|WP_002356760.1\|1914972_1915854_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP018102.1\|WP_002356761.1\|1913989_1914712_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NZ_CP018102.1\|WP_002359745.1\|1924547_1925450_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_CP018102.1\|WP_002356741.1\|1929711_1930161_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP018102.1\|WP_002379669.1\|1921993_1922902_-\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473

Protein	Function_ID	Function_description	E-value
NZ_CP018102.1\|WP_002389231.1\|1928554_1929529_-\|phosphate-starvation-inducible-protein-PhoH	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	4.35931e-144
NZ_CP018102.1\|WP_010715369.1\|1918268_1918544_+\|acylphosphatase	gnl\|CDD\|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	4.22972e-27
NZ_CP018102.1\|WP_002356744.1\|1926327_1928526_-\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	6.87785e-159
NZ_CP018102.1\|WP_002382766.1\|1919676_1919868_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	8.4601e-06
NZ_CP018102.1\|WP_002382768.1\|1918710_1919643_+\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	1.11513e-134
NZ_CP018102.1\|WP_002356740.1\|1930186_1930363_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.30263e-11
NZ_CP018102.1\|WP_002356746.1\|1925463_1925871_-\|diacylglycerol-kinase-family-protein	gnl\|CDD\|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	2.85033e-42
NZ_CP018102.1\|WP_002382772.1\|1916928_1917366_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.78953e-30
NZ_CP018102.1\|WP_002382765.1\|1923670_1924465_-\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	1.19301e-71
NZ_CP018102.1\|WP_002356761.1\|1913989_1914712_-\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	1.02758e-148
NZ_CP018102.1\|WP_071981529.1\|1919907_1921992_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_CP018102.1\|WP_002356745.1\|1925848_1926328_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	4.17563e-61
NZ_CP018102.1\|WP_071981528.1\|1917385_1918162_-\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	4.91424e-72
NZ_CP018102.1\|WP_002356759.1\|1915959_1916745_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	3.78425e-167
NZ_CP018102.1\|WP_002356760.1\|1914972_1915854_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.02636e-146
NZ_CP018102.1\|WP_002356736.1\|1930528_1930963_-\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	8.2692e-35
NZ_CP018102.1\|WP_002359745.1\|1924547_1925450_-\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	0
NZ_CP018102.1\|WP_002356741.1\|1929711_1930161_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.89434e-63
NZ_CP018102.1\|WP_002379669.1\|1921993_1922902_-\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0

>NZ_CP018102.1|WP_002379669.1|1921993_1922902_-|glycine--tRNA-ligase-subunit-alpha
MKNKLTVQEMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLKLLGIDPLEHDIRFVEDNWENPSMGCAGLGWEVWLDGMEITQFTYFQQVGGLQCHPVTSEITYGLERLASYIQEVESVYDLEWTQGVKYGEIFVQPEYEHSKYSFEISNQEMLLENFDKFEKEAKRCIEESLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNMARSVAKIFVAEREKLGFPLLNKDQSVSKEAE
>NZ_CP018102.1|WP_071981529.1|1919907_1921992_-|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGLEEMPAHVVTPSRIQLEEKVIKFLDEHHLDYETVQSFATPRRLAVKVTAIPEKQADVEEEVKGPAKKIALDAEGNWSKAAQGFVRGQGVTTEDIVFKELNGVEYVYVTKFTKGQSAKEVLTKLNDVITSLTFPVTMHWANYDFEYIRPIHWIVALLDDEVIPFNVLDVTTGQTSRGHRFLGDDVTFQHANEYEAKLKEQFVVVQPNERKQMIVDQANALAAEKNWQLALDEELLEEVTNLVEYPTAFVGSFDEKYLSVPDEVLVTSMKEHQRYFEVRNDQGLLMPHFIAVRNGDNVHLENVIKGNEKVLIARLEDAEFFYNEDKKLTIEACVEKLKNVTFHEKIGSIYEKMQRVALIAQIIGRKVGLSEEELEDLKRASEIYKFDLVTNMVGEFPELQGIMGEKYALLQGEKPAVATAIREHYLPTSSEGELPETAIGAVLALADKLDSVFSFFSVGMIPTGSNDPYALRRQTYGVIRIIEDKGWTFPLVQLQTEVDEAVNQDVEKYGVLLNEGQAEVVEFVKARLRQLLMTKNVRHDIIDAVVSAEQADLSKIFASANILKSRFEDQDFKPSMEALTRVINLAKKGQELLGDTEEGIDPSLFENKAEKELYQAVNDLSEAFATRTIAENYEALVNLRPLIDAYFNETMVMVEDEKVKQNRLKQLMQIAKMALSIASLDLLIVK
>NZ_CP018102.1|WP_002382766.1|1919676_1919868_-|hypothetical-protein
MSETTFEQILTQLSKPAVRALTNEKIDSVDELYARGRKALLSLHGFGPKSIRTIEEMTGKELK
>NZ_CP018102.1|WP_002382768.1|1918710_1919643_+|membrane-protein-insertase-YidC
MRKLNRWLYGSGLLFLVMFLSGCVKTGADGQPTGEGFVYNFLVLPMSNAITYLVDNFNWNYGWAIIFITIIVRIIILPLGLHQSKKSFIQTEKMQAIKPQVDVAQAKMKQASTREEQMAAQAELQRIYKENNVSMVGGIGCLPLLIQMPIFSSLFFAARYTKGIATASFLGMNLGQPNMILVALAGLAYLAQGYISMIGIPEEQKKTMKSMLIVSPLMIVFMSFSSPAGVALYWVVGGIFTCIQSAITNILLRPRIKKQVQEELKNNPPKQVVTPIKDVTPKETNKVTQKTNQPKANGNKGRNAGKQKRK
>NZ_CP018102.1|WP_010715369.1|1918268_1918544_+|acylphosphatase
MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVKNEDDGSVSITAMAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
>NZ_CP018102.1|WP_071981528.1|1917385_1918162_-|RNA-methyltransferase
MKEITSTKNNQLKEWKKLHKKKYREELNQYIIEGFHLVEEAVKANADVQWILFNQRGQQEWGTWLAEQETEKLIFVSDEVLNSLSELPTSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVFQRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMFYFENNQ
>NZ_CP018102.1|WP_002382772.1|1916928_1917366_-|GNAT-family-N-acetyltransferase
MLTIKKTTQLTEKELETIMAIWLQTNLEAHPFVAPTYWQENKAFVRAALPKATLILAEEEDQIIGFLGLMDNYIAGIFIKKAFQGKGIGQKLLQVAKEEQDVLSLAVYRENQAAYAFYQKQGFVQQKRTIDETGNEECHLVWQAQ
>NZ_CP018102.1|WP_002356759.1|1915959_1916745_-|30S-ribosomal-protein-S2
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
>NZ_CP018102.1|WP_002356760.1|1914972_1915854_-|elongation-factor-Ts
MADVTAKMVKELRDMTGVGMMDAKKALVKVEGDMEKAVDFLRENGMAKAAKKNDRIAAEGLANVATVGNVAAIVEVNSETDFVSKNEMFQDLVKDIATKVAENKPATMEEAMAIKTEKGTIESDLIEATTVIGEKISFRRFEVVEKADNAAFGAYLHMGGRIAVLTVIDGTTDEEVAKDVAMHIAAINPRYVNESQIPQEELEHEKAVLTEQALNEGKPANIVEKMVVGRLQKFKAEIALVDQPFVKDPDMTVEKFVASKGGEVKSFVRFEVGEGIEKREDNFADEVMSQMKN
>NZ_CP018102.1|WP_002356761.1|1913989_1914712_-|UMP-kinase
MVKPKYQRVVLKLSGEALAGEDGFGIKPPVIKEIVQEIKEVHELGIEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENLGVPTRVQTSIEMRQIAEPYIRRRAERHLEKGRVVIFAGGTGNPYFSTDTTAALRAAEVDADVILMAKNNVDGVYSADPRVDETATKFEELTHLDVISKGLQVMDSTASSLSMDNDIPLVVFNLNEAGNIRRAILGENIGTTVRGK
>NZ_CP018102.1|WP_101731707.1|1923318_1923402_-|hypothetical-protein
MNHYDWRKCDRVDDEQYKVTKGNVVTE
>NZ_CP018102.1|WP_002382765.1|1923670_1924465_-|DNA-repair-protein-RecO
MALGETKGIILFTKDFKEKDKLVKIFTESYGKLMFFVKGAHRKNNPLLPAILPFTEAVYIGNFREEGLSFLNSSKEVQPFRNIQQDIFINAYGTYILNLVDAAIEDQHYDPNLFQFTHMALSALNEQKDPEIITNIFEIQLLERFGVRPEWHHCVACGETQGKFDYSSRYSGVLCEKHWHLDEQRYHADPRAIHFIRLFSQVSYEKVQNIQVKEETKKSIRETIDMLYDEYVGLHLKSKKFIDQMKTWENTLKIPPRKKEEKET
>NZ_CP018102.1|WP_002359745.1|1924547_1925450_-|GTPase-Era
MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSADQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
>NZ_CP018102.1|WP_002356746.1|1925463_1925871_-|diacylglycerol-kinase-family-protein
MRMALKDEQTGKNKHFINSLEFAWQGIKTVFREERNMRKHVAFGVTAIVFGFLFSLTLAEWLWLLLAVFLVWLAEIINTIFENVVDMFTDFHFHPIGKKVKDMAAGAVLLTAGFAVLVGLILFVPKILQIIQMWK
>NZ_CP018102.1|WP_002356745.1|1925848_1926328_-|rRNA-maturation-RNase-YbeY
MDITFIDETEKVPTEEIKEIENLLQFAAGFLEIAEDTEMSVTFTDNAGIQVINRDYRGKDMPTDVISFALEDEGEDELPIIFDDEELAELPRNLGDLIISTERAAEQAVEYGHTLEREMGFLAVHGFLHLNGYDHMEPEDEKEMFGLQKEILDAYGLKR
>NZ_CP018102.1|WP_002356744.1|1926327_1928526_-|HDIG-domain-containing-protein
MKKVLTKLGDRLGKAYLPILLAVFSLLLFMIMFGSVHQKRVEIKEGQLAEKTIRANKNIENTYETEQRKKLAAEAVTPEYIYQEDTASVQHNRIDKLFKLIDSANEKVDKEYSNKQAKAKKEETIPAPTVEERVASLKSLFESLPQDEVTFYQSFPNVFYQTIFTLTSEQLDKVRSESLMLVDDAMQNHVRESDLDKIRQEANGKIQYLDITSTMQQVIRYIVNQGIVVNDIANEKRTEELRQKAMNAVQPAMIYQGEIIVREGTQIDAKAVEKLELLGMTSQNTSIFPMVALALAILLQVEVLIFFTKQVTEPSRQRSFIIFYTGAMLISVILMKFFQIFQTEQLMYIPLFYPAAFAPLILNHFVNRRSGIIAAIFQVVFALFIFYNSIGTNSLTVILIMYLFSGFLATVVKRKRMSEQVFPALMWVVVFPVFMAVVLMIYQGMSLTDGKTWTALICASAGTVLSFLATMGLHPYIELLVTDDSMIVLNELSNPNHPLLKQLLEEAPGTYHHSMMVASLSANAVAEIGGRSLLTRVACYYHDIGKIKHANFFVENLPAGAENPHNFLLPEDSKQIIFGHVIDGAKILEEYNMPQMVIDICRQHHGTTLMKFFYVKAKERNPEIKESDFRYPGPRPQTREAGIVSIADTCEAAVRAMDHPTNEKIQAFVHNVIQDRISDGQLDECGLTMKEIRIIEKSLINGLCSTFHSRIKYPKMKAEAEEMKDEQEKRDD
>NZ_CP018102.1|WP_002389231.1|1928554_1929529_-|phosphate-starvation-inducible-protein-PhoH
MTDNQSKSLELILTDSDDAHMLLGTHDKHIKFLEENTHVTINSRGEVIQLIGESSEVELVASVLRALQTLIQRGIKVHTPDVVSALKMAKAGNLEAFIAMYEEEIMKDHHGRAIRIKNVGQKKYIDAVKTHDVIFGVGPAGTGKTFLAVVMAVAALKKGEVQKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQIFGMDHTNRLMERGVIEIAPLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGFSSKMIVNGDTSQIDLPRGVTSGLVNAERTLKDIEKIAFVNFEASDVVRHPVVAQIIQAYEKEQQKHS
>NZ_CP018102.1|WP_002356741.1|1929711_1930161_-|GatB/YqeY-domain-containing-protein
MSLLTTLNDDIKTAMKAKDKETLAVLRMLKTAIQNDQIKAGRELNGEEELTVLSREMKQRKDSLSEFEKAGRDDLVEKVKVEIAIVEKYMPQQLTEEEIRQLVQEVMTQTGATSPKDFGKVMGAMMPKVKGKADGNQVNAIVKELLQEN
>NZ_CP018102.1|WP_002356740.1|1930186_1930363_-|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
>NZ_CP018102.1|WP_002356736.1|1930528_1930963_-|transcriptional-repressor
MAPVKTNIEQALETMKASGLKYTKKRELLMSYLIKRNRYVSAREVYEFMNETFKGVSYDTVYRNLHDFERLELLEKTELNGEQKFRFRCCQEVEHHHHFICTVCGKTEEIHMCPMNFFEEQLKGCSIEGHRFEILGRCADCCEK

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Crispr_ID: NZ_CP018102_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018102_4

2538690-2538763

Orphan

Consensus_repeat	Method
ATAGTTGGCGAGCAACAGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018102_4

>merge|NZ_CP018102|4|2538690-2538763|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAACTCGATATAGAATTGGACGTAGAGCCAATAGTTGGTGAGCAACAGAAAAAC

>NZ_CP018102|4|3|2538690-2538763|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAAC	TCGATATAGAATTGGACGTAGAGCCA
ATAGTTGGTGAGCAACAGAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018102.1\|WP_002359021.1\|2527469_2527682_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018102.1\|WP_002354885.1\|2528840_2530145_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP018102.1\|WP_002354877.1\|2533983_2534697_-\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NZ_CP018102.1\|WP_002354868.1\|2542463_2544596_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|223400
NZ_CP018102.1\|WP_002378823.1\|2532104_2532812_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP018102.1\|WP_002354864.1\|2547663_2548461_-\|TIGR00282-family-metallophosphoesterase	unknown	unknown	gnl\|CDD\|379099
NZ_CP018102.1\|WP_002354875.1\|2537716_2538367_+\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672
NZ_CP018102.1\|WP_002354871.1\|2541314_2541752_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP018102.1\|WP_002360992.1\|2527806_2528673_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NZ_CP018102.1\|WP_002378825.1\|2534957_2537702_+\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|224471
NZ_CP018102.1\|WP_002401680.1\|2532907_2533588_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP018102.1\|WP_002378831.1\|2551733_2552978_-\|competence/damage-inducible-protein-A	unknown	unknown	gnl\|CDD\|234789
NZ_CP018102.1\|WP_002354883.1\|2531614_2532064_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP018102.1\|WP_002378827.1\|2541884_2542439_-\|septum-formation-protein-Maf	unknown	unknown	gnl\|CDD\|238310
NZ_CP018102.1\|WP_002368461.1\|2530137_2531406_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP018102.1\|WP_002354866.1\|2547204_2547576_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226923
NZ_CP018102.1\|WP_002381060.1\|2540168_2541140_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP018102.1\|WP_002354863.1\|2548620_2550177_-\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NZ_CP018102.1\|WP_002354860.1\|2550573_2551620_-\|recombinase-RecA	unknown	unknown	gnl\|CDD\|236476
NZ_CP018102.1\|WP_002378828.1\|2544627_2547204_-\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444

Protein	Function_ID	Function_description	E-value
NZ_CP018102.1\|WP_002354885.1\|2528840_2530145_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	3.18356e-85
NZ_CP018102.1\|WP_002354877.1\|2533983_2534697_-\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	6.92052e-137
NZ_CP018102.1\|WP_002354868.1\|2542463_2544596_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|223400	COG0323, MutL, DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair].	0
NZ_CP018102.1\|WP_002378823.1\|2532104_2532812_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.3494e-16
NZ_CP018102.1\|WP_002354864.1\|2547663_2548461_-\|TIGR00282-family-metallophosphoesterase	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	2.68643e-155
NZ_CP018102.1\|WP_002354875.1\|2537716_2538367_+\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	7.1375e-106
NZ_CP018102.1\|WP_002354871.1\|2541314_2541752_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.48715e-93
NZ_CP018102.1\|WP_002360992.1\|2527806_2528673_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	8.53832e-35
NZ_CP018102.1\|WP_002378825.1\|2534957_2537702_+\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	1.11964e-173
NZ_CP018102.1\|WP_002401680.1\|2532907_2533588_-\|hypothetical-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	6.52526e-09
NZ_CP018102.1\|WP_002378831.1\|2551733_2552978_-\|competence/damage-inducible-protein-A	gnl\|CDD\|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	0
NZ_CP018102.1\|WP_002354883.1\|2531614_2532064_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.8499e-49
NZ_CP018102.1\|WP_002378827.1\|2541884_2542439_-\|septum-formation-protein-Maf	gnl\|CDD\|238310	cd00555, Maf, Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.	3.23253e-85
NZ_CP018102.1\|WP_002368461.1\|2530137_2531406_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.21959e-51
NZ_CP018102.1\|WP_002354866.1\|2547204_2547576_-\|hypothetical-protein	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	8.72333e-15
NZ_CP018102.1\|WP_002381060.1\|2540168_2541140_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP018102.1\|WP_002354863.1\|2548620_2550177_-\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NZ_CP018102.1\|WP_002354860.1\|2550573_2551620_-\|recombinase-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0
NZ_CP018102.1\|WP_002378828.1\|2544627_2547204_-\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0

>NZ_CP018102.1|WP_002354875.1|2537716_2538367_+|beta-phosphoglucomutase
MTIGFIFDLDGVITDTAKFHYQAWKALADSLGISIDETFNETLKGISRMDSLDRILAHGHRENAFTPAEKEALAQQKNDHYVQLLEHLTTEDVLPGVVPLLQQAQARHIPCAVASASKNAPLILEKLGVRAYFATIVDPDSLSKGKPDPEIFLAAADSIGVLPQNAIGFEDAQSGIDGLKAAGIYAVGLSASQPLIGADMQVSEMTELSVDALLNR
>NZ_CP018102.1|WP_002378825.1|2534957_2537702_+|glycoside-hydrolase-family-65-protein
MSIQVHKEAPNMTILELTFATNQLTTTFFNHKLEPLHQKTFPFEALTIEETVPELCQLIVAEAAPILGGIVADFPEDFFSPEETLALVPQAVIQAFAEQLNTPLLTAAEQAAAPNLLAAFEEKRQYLAWHLDYYGYVPGKNEYAVESLLTVGNGFLGLRGTTPEMTISDDHYPATYIAGLYNTAASEVAGQVVENEDFVNAPDNQHIALKIGDATDWLTISPDTLQQLHRQLNLKTGLFVAEMILKDADNQQIKLTTKKIANMAQPNDYHLQYTFEPLNFSAPITLKTVTDGSVYNYNVARYRNLTAKHFQVTALSAQENKTVIEVCTNQSNLSVRETALITGDFFEKEAIMIQEEAEKIAQVVTVMAHQGTRYTLEKQVFVQASHAEQSWQVPFTPKDSFAAAAQESARAWQTLWQQANITVTGDLMSQKLLRIHSYHLLASASPFSNQAQALDVSITARGLHGEAYRGHIFWDEIFILPFYIQHYPDTAKQLLLYRYHRLEKAKENAAASQYRGAMYPWQSGRDGRETTQKLHLNPLNGHWGEDHSILQRHVSLAIAYNAWLYWHSTQDHEFMKQYGGEMLLEIAQFWNSAATLDDATGRFFIDKVMGPDEFHEGYPDQAESGLKNNAYTNLMVVWLFEELTNILALFSEEEQAQLFAKTQTTSADLARMQQIQNSLEIEVNSDGIIAQYEGYFGLKEIDWAAMKEKYGNIYRMDRILKAEGESPDDYKVAKQADTLMLFYNLDKTRVDQILEDLGYQLPADYLEKNLLYYLKRTSHGSTLSRIVHAQLAEMAQFHELSWQLYQEALYSDYRDIQGGTTAEGIHTGVMAATIHVTLATYAGVDTRQNELSICPNLPEHWQALAFQFIHQGVTYQFSLTQTSVTITADKDTQLLVQGALIPLTAERPKEVHYQ
>NZ_CP018102.1|WP_002354877.1|2533983_2534697_-|trehalose-operon-repressor
MNKFHDIFLELEQQIVQGDYQPGDLLPSENQLVETYNVSRETIRKALNLLINAGYIQKKQGKGSIVLNFKKFNFPISGVTSYKELQQTQHIESHTHVVSLEEIPVERNLAQLTGWTEGAPVWRLVRQREIEGEVDILDIDYLIKEIVPELPKHRAEDSIFDYLENDLGLAISYAQKEITVEPLTEMDKQLIGEVEGNHVVVVRSIMNLEDTRCFGYTESRHRLNKFKFVEFARRRKL
>NZ_CP018102.1|WP_002401680.1|2532907_2533588_-|hypothetical-protein
MKKKIMASLLVGSAVVGASLAPLSAQATTTGNTPVSVGVEGGVLPEGNYGGAIDPDPNTLNSDFDLLYIPRSISFAKTAISDDLSSIKSSSYANYAVGDLRGTKEGWHVTATILEMVNGGDKLAGAVSFNQVGYVAYYDEVDNRFKVESVGSFNSSPVAPEFPTSRSITIGGGALLVGNAVSGKGQGMWNSYMTDPTLNITTPYQQIKAGTYTGEIAWNLVAGPSV
>NZ_CP018102.1|WP_002378823.1|2532104_2532812_-|WxL-domain-containing-protein
MKKKIMASLLVGSAVVGASLAPLSAQAVTTGNTPVQVEFGGGTLPDGNSKDGNSVDPDPEGSNSNFDLLFIPREFDFGTLSISDDLTQPIFNKADHLNGEDREGVGVGDLRGTKEGWHLTAQSSGLTQGSENLQGTIAVRQVYSNVLRYDETTNEFTSYGSILETAPNIPIRNNWTMDLGGDAKLLANATAGNGQGLWKIGMWSTSLTITTSAYGIKAGNYTGNITWNLVAGPSI
>NZ_CP018102.1|WP_002354883.1|2531614_2532064_+|large-conductance-mechanosensitive-channel-protein-MscL
MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSEDYLKEIRDLLAAQTPPAETVKTDSTFTEK
>NZ_CP018102.1|WP_002368461.1|2530137_2531406_-|insulinase-family-protein
MSVQLVKGVNLHVIPTEKYKTVRLLVRFNTRLNHETITKRTLLSSLMETNSLNYPNQVKLSERLAELYGASFGIGVSKKGNQHWFNISMNIVNDHYLQDSQVLAEAVDFLKEIIFAPNIQAGQFEAETFQREKENLKAYLESIVEDKQTYASLALQSVYFNQSEDQKIPSFGTVAALAEETAASLAAYYQKMLAEDQVDIFVLGDVNEAELVPLFKQLPFTPREEGKAAIFYNQPIRNVIEERTEREVLAQSKLNLAYNTDIYYGDSYYFALQVFNGIFGGFPHSKLFMNVREKEHLAYYASSSIDTFRGFMTVQTGIDGKNRNQVLRLISTELENIRLGKISELEIEQTKAMLKNQYILALDNAGAWLEKEYLNQLMPQTMLTAEEWIARINAVTISEIQEVAKRLELQAIFFLEGETEND
>NZ_CP018102.1|WP_002354885.1|2528840_2530145_-|insulinase-family-protein
MIKKDYAQIKETLYTETLANGLKVYLLPKNDFQKTYGLFTTDYGSIDNTFVPIGQEEMIEVPDGIAHFLEHKMFEKEDGDVFQKFGQQGASANAFTSFTKTSYLFSTTDQVTQNLETLLDFVQSPYFTKETVEKEKGIIGQEIQMYLDDPNWRLFFGILGNLYPKHPLHIDIAGTVASIAEITAEDLYTCYNTFYHPSNMTLFVVGKMDPEALMAFIRENQAAKEFPAAQPIRRHFPEETAADIVKESAIEMAVTRAKVLVGLKGLDEVPTTGRDLMKYQVTVNLLLQLLFGNTSQNYLALYDEGLLDDSFSYDFNLDRSFHFADIGGDSEQPEVLAERIEAILLSATTSPELTEENLSLLKKKMIGKYFQSLNSLEYIANQFSQSLFGETTLFDKIEVIESIQLADVRQVAETLIREEGLSRFYMYPKGETEQ
>NZ_CP018102.1|WP_002360992.1|2527806_2528673_-|helix-turn-helix-domain-containing-protein
MASVNIGETLKEARLQKNISIDELQQMTKIQKRYLEIIEQNDFESLPGTFYVRAFIRQYASAVGLDGNQLVDIYDGKEPAIVEEPKPVYEELEGSRKQLHDEEKQSSWLLRNLPAIAFSLIGLAIAVVVLYIMWQDQKAEPIIQTPATSASVEKPKESSQAPESSTQSSTPPSSSSEPEKKTAVAVVSDANNQVTATVKDANSPINITFKGTEGSCWIGVMVDGNYTYQHTLQAGETETTALPANAANATLILGASNNVAIQVDGADLTLEKTPVLIRKDVTLGITYR
>NZ_CP018102.1|WP_002359021.1|2527469_2527682_-|hypothetical-protein
MLKIVNKKFNLITIFSIALLVMGFLIVGLQLYFYFIYGSKFLDSITLIGMINLGLGYYQLFLKKGKNISE
>NZ_CP018102.1|WP_002381060.1|2540168_2541140_-|ribose-phosphate-diphosphokinase
MSKHYFDPRLKIFSLNSNRPLAEKIADAVGVELGKCSVTQFSDGEIQVNIEESIRGAHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYARQDRKARAREPITAKLVANMIEKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIADYFIEHGIQGDDVVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPKANVAEVMNIIGHVEGKTCVLIDDMIDTAGTISLAANALKEAGAKDVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLSDDRKIAKIDEVSVGELIGDAIKRIHENKPVSPLFETKNK
>NZ_CP018102.1|WP_002354871.1|2541314_2541752_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
>NZ_CP018102.1|WP_002378827.1|2541884_2542439_-|septum-formation-protein-Maf
MQIILASQSPRRQELLKRVVPAFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTDTEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN
>NZ_CP018102.1|WP_002354868.1|2542463_2544596_-|DNA-mismatch-repair-endonuclease-MutL
MGKIQELSEQLANQIAAGEVVERPASVVKELVENALDAGSTQIDIFIEEAGLKTIQIIDNGEGIAKEDVLNAFKRHATSKIHTRDDLFRIRSLGFRGEALPSIASVSEMIVETATAEEEEGSYVILKGGKVEENRPAALRKGTKMTVSNLFYNTPARLKYVKTIQTELANIGDIVNRLALSHPKVAFRLVHDGHKMMSTTGNGDLKQTIAGIYGISTAKKMLKIEGKDLDFTLTGYVSLPEVTRASRNYLSTIINGRYIKNFALNKAIVAGYGSKLMVGRFPIAVLEIEMDPLLVDVNVHPTKQEVRLSKEKDLMALIEQAIQEVLSQEQLIPNAADNLRFKKKLPPEPKAEQMEIPLSTEQPAVKQRPGSLSYNPATGRFYAEHATDETPASSAPEAVNQTERAVDPMDDPFAPPVPESTSVAEETSAYETSSAAVDSENHWETASNEQQVIAEETKITEVPDSEPSLRSSEAADEVFQEEMKLHPEFDANSATSQRELKQALNKLEEERPTERFPELEYFGQMHGTYLFAQSKDGLFIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPIVIDYPNSDALKIKEQKETLAEVGIHLEDFGQNSFIVRAHPTWYPAGEEESIVREMIDMLLTTGSVSVKKFREATAIMMSCKRSIKANHYLNEQQARVLLKDLALCENPFNCPHGRPVLIHFTNSDMERMFKRIQDPH
>NZ_CP018102.1|WP_002378828.1|2544627_2547204_-|DNA-mismatch-repair-protein-MutS
MPQKTKNTPMMEQYLSIKAQYKDAFLFYRLGDFYELFYEDAINAAQILELTLTSRNRNADDPIPMCGVPYHAAQGYIDTLIEQGYKVAICEQVEDPKTTKGMVKREVVQLVTPGTVMNSKGLEAKDNNYLTAVLTDGNQFGFAYVDLSTGELKTAVLADEEGVLNEASALQTKEMVLGSGIPESLKENLSLRLNIIFSTQETVEENAEFSFLTNELINPLEIEITGKLLSYLSVTQKRSLSHIQKAVEYQPDHFLKMDHYSKFNLELSQSIRTGQKKGTLLWLLDETKTAMGGRLLKQWLDRPLIQERQIKERQEMVQSLLNAYFERLDLQAALTNVYDLERLAGRVAFGSVNGRDLIQLRTSLEQVPTIRQLIVGINQGEWDDLLVDLNPVEDLVALIATAINEEAPLQITEGNVIKDGYNDQLDEYRDAMRNGKQWLAELEAKERQETGIKNLKIGYNRVFGYFIEITKSNLANLEEGKYERKQTLANAERFITPELKELERLILEAEEKSVELEYQLFLAVREQVKTNIDRLQTLAKTISAVDVLQSFATISERYQYVRPTLRSNTKNLAIVEGRHPVVEKVLGHQEYIPNSIRMNPETDILLITGPNMSGKSTYMRQLALTVVMAQIGCFVPAESAEMPIFDQIFTRIGASDDLIAGQSTFMVEMMEANQALRHATPNSLILFDELGRGTATYDGMALAQAIIEYIHREVQAKTLFSTHYHELTVLDETLKGLKNIHVGAVEKDGEVVFLHKMMEGPADKSYGIHVAKIAGLPSPLLERAATILSALEAEETTIPISVHHEEVSEVHEETEQLSLFKEVSTEELSVIDTLKKMNLLEMTPLDALNMLHQLQKRI
>NZ_CP018102.1|WP_002354866.1|2547204_2547576_-|hypothetical-protein
MEPLNLDAQSNKELEKLLHLIGQDEVIQRYQAIEEKVKKNKKLTELVEEIKAAQKDAVQFAHYGKPTAEKEAIQRADAKTKEFDEHPLVVAYREQLIEANDLVQHVTALIQYRVNEELEKEGN
>NZ_CP018102.1|WP_002354864.1|2547663_2548461_-|TIGR00282-family-metallophosphoesterase
MRILFIGDVVGSLGREALATYVPKLKKKYRPQVTIANGENAASGRGITGKIYKKFLQDGVDVVTMGNHTWDNKDIFEFIDDAKKMVRPANFPEDVPGQGMVFVKVNQLELAVINLQARTFMVPLEDPFKKAAELVAIARKRTPLIFVDFHGETTSEKQAMSWFLDGQVSAVVGTHTHVQTNDARILPKGTAFLSDVGMTGPYDGILGMKREPIIEKFMTALPKRFEVVETGRTILSACILEIDDQTGQAKMIEPIQISEDRPFQE
>NZ_CP018102.1|WP_002354863.1|2548620_2550177_-|ribonuclease-Y
MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENARKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEEELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIEVAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDSSFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYAK
>NZ_CP018102.1|WP_002354860.1|2550573_2551620_-|recombinase-RecA
MADDRKVALDAALKKIEKNFGKGSIMKLGEKADQKISTIPSGSLALDVALGVGGYPRGRIIEVYGPESSGKTTVSLHAIAEVQRNGGTAAFIDAEHALDPQYAEKLGVNIDELLLSQPDTGEQGLEIADALVSSGAIDIVVIDSVAALVPRAEIDGEMGASHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPETTPGGRALKFYATVRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKVAEVDIMYGQGISQEGELLDMAVEKDLISKSGAWYGYKEERIGQGRENAKQYMADHPEMMAEVSKLVRDAYGIGDGSTITEEAEGQEELPLDE
>NZ_CP018102.1|WP_002378831.1|2551733_2552978_-|competence/damage-inducible-protein-A
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQVVAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMFQQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATEEKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISHELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTIAECFHFNRDRNYIRQSAVMRGLDLLRRRIINKK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	16145-16185	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NC_014726	Enterococcus faecalis plasmid pTW9, complete sequence	22839-22879	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP028722	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence	38730-38770	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	76510-76550	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP028721	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence	9195-9235	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP028286	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence	46841-46881	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	66835-66875	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NC_002630	Enterococcus faecalis plasmid pAM373, complete sequence	29085-29125	0	1.0
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP031029	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence	38617-38657	1	0.976
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP028838	Enterococcus faecalis strain FC plasmid unnamed3, complete sequence	13635-13675	1	0.976
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_AP018539	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence	21806-21846	1	0.976
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_MK993385	Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence	21805-21845	1	0.976
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	32714-32754	1	0.976
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	46756-46796	1	0.976
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_CP019513	Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence	4931-4971	1	0.976
NZ_CP018102_1	1.1\|421008\|41\|NZ_CP018102\|PILER-CR	421008-421048	41	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	78157-78197	1	0.976
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	32640-32671	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	16228-16259	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	46682-46713	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_014726	Enterococcus faecalis plasmid pTW9, complete sequence	22922-22953	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031029	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence	38700-38731	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP019513	Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence	4857-4888	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028838	Enterococcus faecalis strain FC plasmid unnamed3, complete sequence	13718-13749	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028721	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence	9121-9152	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028722	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence	38813-38844	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028286	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence	46767-46798	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	66761-66792	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_AP018539	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence	21889-21920	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_002630	Enterococcus faecalis plasmid pAM373, complete sequence	29011-29042	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	78083-78114	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK993385	Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence	21888-21919	2	0.938
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	32676-32707	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	16192-16223	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	46718-46749	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_014726	Enterococcus faecalis plasmid pTW9, complete sequence	22886-22917	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031029	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence	38664-38695	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP019513	Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence	4893-4924	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028838	Enterococcus faecalis strain FC plasmid unnamed3, complete sequence	13682-13713	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028721	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence	9157-9188	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028722	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence	38777-38808	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028286	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence	46803-46834	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	66797-66828	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_002630	Enterococcus faecalis plasmid pAM373, complete sequence	29047-29078	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	78119-78150	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK993385	Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence	21852-21883	3	0.906
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028838	Enterococcus faecalis strain FC plasmid unnamed3, complete sequence	13754-13785	6	0.812
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	76472-76503	6	0.812
NZ_CP018102_2	2.4\|489399\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489399-489428	30	NZ_CP043436	Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence	10209-10238	6	0.8
NZ_CP018102_2	2.4\|489399\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489399-489428	30	NZ_CP014570	Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence	14813-14842	6	0.8
NZ_CP018102_2	2.4\|489399\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489399-489428	30	NZ_CP008809	Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence	2921-2950	6	0.8
NZ_CP018102_2	2.4\|489399\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489399-489428	30	NZ_CP008812	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence	10382-10411	6	0.8
NZ_CP018102_2	2.7\|489597\|30\|NZ_CP018102\|CRISPRCasFinder,CRT,PILER-CR	489597-489626	30	NZ_CP009691	Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence	40757-40786	6	0.8
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	32604-32635	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	16264-16295	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	46646-46677	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_014726	Enterococcus faecalis plasmid pTW9, complete sequence	22958-22989	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031029	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence	38736-38767	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP019513	Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence	4821-4852	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028721	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence	9085-9116	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028722	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence	38849-38880	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028286	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence	46731-46762	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	66725-66756	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_AP018539	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence	21925-21956	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_002630	Enterococcus faecalis plasmid pAM373, complete sequence	28975-29006	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	78047-78078	7	0.781
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK993385	Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence	21924-21955	7	0.781
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	9754-9783	7	0.767
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	20272-20301	7	0.767
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_AP018539	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence	21763-21794	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	78209-78240	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MK993385	Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence	21762-21793	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP041739	Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence	66816-66847	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP022485	Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence	38726-38757	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	14738-14769	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	CP002493	Enterococcus faecalis 62 plasmid EF62pB, complete sequence	15400-15431	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031072	Bacillus mycoides strain BPN401 plasmid pl395, complete sequence	373478-373509	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP008815	Enterococcus faecalis ATCC 29212 plasmid 1, complete sequence	30968-30999	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_006827	Enterococcus faecalis plasmid pCF10, complete sequence	17661-17692	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	12913-12944	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028283	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence	29155-29186	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP030044	Enterococcus faecalis strain C25 plasmid pC25-2, complete sequence	46688-46719	8	0.75
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_MG765452	Enterococcus faecalis strain E512 plasmid pE512, complete sequence	39455-39486	8	0.75
NZ_CP018102_2	2.3\|489333\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489333-489362	30	NZ_CP010111	Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-5, complete sequence	134723-134752	8	0.733
NZ_CP018102_2	2.5\|489465\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489465-489494	30	NZ_CP053022	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence	219326-219355	8	0.733
NZ_CP018102_2	2.5\|489465\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489465-489494	30	NZ_CP053224	Sphingobium sp. RSMS plasmid pRSMS1, complete sequence	48396-48425	8	0.733
NZ_CP018102_2	2.5\|489465\|30\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489465-489494	30	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	710636-710665	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP031904	Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence	60569-60598	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NC_018654	Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence	17881-17910	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP023530	Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence	6482-6511	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP041001	Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence	63459-63488	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	CP025574	Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence	51314-51343	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP023533	Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence	24355-24384	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP027392	Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence	4511-4540	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP023062	Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence	55180-55209	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP023552	Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence	47364-47393	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_KY706108	Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence	60040-60069	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NC_011752	Escherichia coli 55989 plasmid 55989p, complete sequence	49973-50002	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	CP042952	Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence	67474-67503	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP026724	Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence	101148-101177	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	CP051693	Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence	31503-31532	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NC_019000	Escherichia coli plasmid pHUSEC41-2, complete sequence	51056-51085	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP009053	Escherichia coli NCCP15648 plasmid p15648-3, complete sequence	55603-55632	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NC_018666	Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence	10746-10775	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NC_018662	Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence	58558-58587	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP013186	Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence	39899-39928	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NZ_CP022087	Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence	40046-40075	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	CP049615	Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence	17811-17840	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	NC_022743	Escherichia coli plasmid pHUSEC2011-2, complete sequence	53979-54008	8	0.733
NZ_CP018102_2	2.9\|489729\|30\|NZ_CP018102\|CRISPRCasFinder,CRT	489729-489758	30	KU886273	Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome	26680-26709	8	0.733
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	32784-32815	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	16084-16115	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	46826-46857	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_014726	Enterococcus faecalis plasmid pTW9, complete sequence	22778-22809	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031029	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence	38556-38587	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP019513	Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence	5001-5032	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028838	Enterococcus faecalis strain FC plasmid unnamed3, complete sequence	13574-13605	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028721	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence	9265-9296	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028722	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence	38669-38700	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP028286	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence	46911-46942	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	66905-66936	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_002630	Enterococcus faecalis plasmid pAM373, complete sequence	29155-29186	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	76580-76611	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP034685	Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence	41808-41839	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	51888-51919	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	52266-52297	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031072	Bacillus mycoides strain BPN401 plasmid pl395, complete sequence	373460-373491	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031072	Bacillus mycoides strain BPN401 plasmid pl395, complete sequence	373514-373545	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	51593-51624	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	51683-51714	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	51701-51732	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	CP024686	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence	313033-313064	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	169625-169656	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	169661-169692	9	0.719
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	52122-52153	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	52320-52351	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP031072	Bacillus mycoides strain BPN401 plasmid pl395, complete sequence	373442-373473	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	51377-51408	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	51485-51516	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	51557-51588	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	51611-51642	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	CP024686	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence	312835-312866	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21162-21193	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21198-21229	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21234-21265	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21270-21301	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21306-21337	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21342-21373	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21378-21409	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21450-21481	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21486-21517	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21522-21553	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21558-21589	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21594-21625	10	0.688
NZ_CP018102_1	1.2\|421100\|32\|NZ_CP018102\|PILER-CR	421100-421131	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	21630-21661	10	0.688
NZ_CP018102_2	2.1\|489199\|32\|NZ_CP018102\|PILER-CR,CRISPRCasFinder,CRT	489199-489230	32	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1915425-1915456	10	0.688

1. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

2. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NC_014726 (Enterococcus faecalis plasmid pTW9, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

3. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP028722 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

4. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

5. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP028721 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

6. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP028286 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

7. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

8. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NC_002630 (Enterococcus faecalis plasmid pAM373, complete sequence) position: , mismatch: 0, identity: 1.0

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
tacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
*****************************************

9. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP031029 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

10. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP028838 (Enterococcus faecalis strain FC plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

11. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_AP018539 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

12. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_MK993385 (Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

13. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NC_004669 (Enterococcus faecalis V583 plasmid pTEF1, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

14. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

15. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_CP019513 (Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

16. spacer 1.1|421008|41|NZ_CP018102|PILER-CR matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 1, identity: 0.976

tacaactcctacagagccaagtgaaccagaacaaccaacgg	CRISPR spacer
gacaactcctacagagccaagtgaaccagaacaaccaacgg	Protospacer
 ****************************************

17. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_004669 (Enterococcus faecalis V583 plasmid pTEF1, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

18. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

19. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

20. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_014726 (Enterococcus faecalis plasmid pTW9, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

21. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031029 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

22. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP019513 (Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

23. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028838 (Enterococcus faecalis strain FC plasmid unnamed3, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

24. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028721 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

25. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028722 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

26. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028286 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

27. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

28. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_AP018539 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

29. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_002630 (Enterococcus faecalis plasmid pAM373, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

30. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

31. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK993385 (Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence) position: , mismatch: 2, identity: 0.938

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gcaaaccagcagaacccgaaaaacctgtgaca	Protospacer
************************* ** ***

32. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_004669 (Enterococcus faecalis V583 plasmid pTEF1, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

33. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

34. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

35. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_014726 (Enterococcus faecalis plasmid pTW9, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

36. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031029 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

37. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP019513 (Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

38. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028838 (Enterococcus faecalis strain FC plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

39. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028721 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

40. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028722 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

41. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028286 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

42. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

43. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_002630 (Enterococcus faecalis plasmid pAM373, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

44. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

45. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK993385 (Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence) position: , mismatch: 3, identity: 0.906

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagttaca	Protospacer
*.*******.******.***************

46. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028838 (Enterococcus faecalis strain FC plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.812

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccaacagaacctgaaaaaccagtacaa	Protospacer
*.******.*******.***********   *

47. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 6, identity: 0.812

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccagtagaacctgaaaaaccagtacaa	Protospacer
*.*******.******.***********   *

48. spacer 2.4|489399|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043436 (Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

49. spacer 2.4|489399|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014570 (Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

50. spacer 2.4|489399|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008809 (Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

51. spacer 2.4|489399|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008812 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

52. spacer 2.7|489597|30|NZ_CP018102|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009691 (Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence) position: , mismatch: 6, identity: 0.8

tgatgaaaaccgatggtatttactttcaca	CRISPR spacer
aggtaaaaaccgatggtattttctttcgaa	Protospacer
 *.*.**************** *****. *

53. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_004669 (Enterococcus faecalis V583 plasmid pTEF1, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

54. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

55. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

56. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_014726 (Enterococcus faecalis plasmid pTW9, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

57. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031029 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

58. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP019513 (Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

59. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028721 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

60. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028722 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

61. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028286 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

62. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

63. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_AP018539 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

64. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_002630 (Enterococcus faecalis plasmid pAM373, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

65. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

66. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK993385 (Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence) position: , mismatch: 7, identity: 0.781

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
ctaaaccaacagaacctgaaaaaccagtacaa	Protospacer
 .******.*******.***********   *

67. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tctaatgagcattcattacatatgtagaac	CRISPR spacer
ttaaatgagcattcattacttatatacatt	Protospacer
*. **************** ***.** * .

68. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tctaatgagcattcattacatatgtagaac	CRISPR spacer
ttaaatgagcattcattacttatatacatt	Protospacer
*. **************** ***.** * .

69. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_AP018539 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagaa	Protospacer
  * ****.*******.*********** . *

70. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagaa	Protospacer
  * ****.*******.*********** . *

71. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MK993385 (Enterococcus faecalis strain P010748 plasmid pEF10748, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagaa	Protospacer
  * ****.*******.*********** . *

72. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP041739 (Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

73. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP022485 (Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

74. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

75. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to CP002493 (Enterococcus faecalis 62 plasmid EF62pB, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

76. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031072 (Bacillus mycoides strain BPN401 plasmid pl395, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccaacagaaccggaaaaaccaacagaa	Protospacer
*.******.******* *********.. . *

77. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP008815 (Enterococcus faecalis ATCC 29212 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

78. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_006827 (Enterococcus faecalis plasmid pCF10, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

79. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

80. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028283 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

81. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP030044 (Enterococcus faecalis strain C25 plasmid pC25-2, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

82. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_MG765452 (Enterococcus faecalis strain E512 plasmid pE512, complete sequence) position: , mismatch: 8, identity: 0.75

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccagcagaaccagaaacaccaaaaact	Protospacer
. ************** **** ****.  **

83. spacer 2.3|489333|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010111 (Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-5, complete sequence) position: , mismatch: 8, identity: 0.733

acgtgccttcaaatccaaaaaaggtttgtt	CRISPR spacer
aaacaacttcaaatcctaaaaaggattgta	Protospacer
* ... ********** ******* ****

84. spacer 2.5|489465|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053022 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence) position: , mismatch: 8, identity: 0.733

ttagaaaa---gacgtgacagagcaaacagcgc	CRISPR spacer
---gagcgtctgacgtgacagaggaaacagcga	Protospacer
   **. .   ************ ********

85. spacer 2.5|489465|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053224 (Sphingobium sp. RSMS plasmid pRSMS1, complete sequence) position: , mismatch: 8, identity: 0.733

ttagaaaa---gacgtgacagagcaaacagcgc	CRISPR spacer
---gagcgtctgacgtgacagaggaaacagcga	Protospacer
   **. .   ************ ********

86. spacer 2.5|489465|30|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 8, identity: 0.733

ttagaaaa---gacgtgacagagcaaacagcgc	CRISPR spacer
---gagcgtctgacgtgacagaggaaacagcga	Protospacer
   **. .   ************ ********

87. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP031904 (Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

88. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NC_018654 (Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

89. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP023530 (Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

90. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP041001 (Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

91. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to CP025574 (Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

92. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP023533 (Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

93. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP027392 (Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

94. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP023062 (Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

95. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP023552 (Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

96. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_KY706108 (Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

97. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NC_011752 (Escherichia coli 55989 plasmid 55989p, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

98. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to CP042952 (Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

99. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP026724 (Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

100. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to CP051693 (Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

101. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NC_019000 (Escherichia coli plasmid pHUSEC41-2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

102. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP009053 (Escherichia coli NCCP15648 plasmid p15648-3, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

103. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NC_018666 (Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

104. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NC_018662 (Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

105. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP013186 (Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

106. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NZ_CP022087 (Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

107. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to CP049615 (Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

108. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to NC_022743 (Escherichia coli plasmid pHUSEC2011-2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

109. spacer 2.9|489729|30|NZ_CP018102|CRISPRCasFinder,CRT matches to KU886273 (Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
ttgggctagtattcattacaaatgtagaac	Protospacer
*. ... **.********** *********

110. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_004669 (Enterococcus faecalis V583 plasmid pTEF1, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagtt	Protospacer
  * ****.*******.*********** ..

111. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

112. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

113. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_014726 (Enterococcus faecalis plasmid pTW9, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

114. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031029 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagtt	Protospacer
  * ****.*******.*********** ..

115. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP019513 (Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagtt	Protospacer
  * ****.*******.*********** ..

116. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028838 (Enterococcus faecalis strain FC plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

117. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028721 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

118. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028722 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-2, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

119. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP028286 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

120. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

121. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_002630 (Enterococcus faecalis plasmid pAM373, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

122. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
caacaccaacagaacctgaaaaaccagtagag	Protospacer
  * ****.*******.*********** . .

123. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP034685 (Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

124. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccagaaaaaccaacgaat	Protospacer
. ******.******* *********.. *

125. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccagaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

126. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031072 (Bacillus mycoides strain BPN401 plasmid pl395, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccggaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

127. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031072 (Bacillus mycoides strain BPN401 plasmid pl395, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
gtaaaccaacagaaccggaaaaaccaacagat	Protospacer
*.******.******* *********.. .

128. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccagaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

129. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

130. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccggaaaaaccaacaaat	Protospacer
. ******.******* *********.. *

131. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to CP024686 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

132. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

133. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 9, identity: 0.719

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagaa	Protospacer
. ******.******* *********.. . *

134. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

135. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

136. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP031072 (Bacillus mycoides strain BPN401 plasmid pl395, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

137. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

138. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

139. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

140. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

141. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to CP024686 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagag	Protospacer
. ******.******* *********.. . .

142. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

143. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

144. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

145. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

146. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

147. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

148. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

149. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

150. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

151. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

152. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

153. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
aaaaaccaacagaaccggaaaaaccaacagat	Protospacer
. ******.******* *********.. .

154. spacer 1.2|421100|32|NZ_CP018102|PILER-CR matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaaccagcagaacccgaaaaaccagttaca	CRISPR spacer
agaaaccaacagaaccagaaaaaccaacagat	Protospacer
. ******.******* *********.. .

155. spacer 2.1|489199|32|NZ_CP018102|PILER-CR,CRISPRCasFinder,CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 10, identity: 0.688

actgctcattcgttttctcctcctaacacgct	CRISPR spacer
actgctcattcgtttccccctccgcgaattgc	Protospacer
***************.*.*****  . *.  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

730876 : 738797

Planktothrix_phage(16.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355794.1\|730876_731935_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
WP_002361357.1\|731934_732891_+	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	4.2e-06	23.9
WP_002355796.1\|732931_734002_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	7.6e-89	49.0
WP_002355797.1\|734401_734923_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355798.1\|735036_735237_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355799.1\|735297_735657_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002363280.1\|735703_736054_-	hypothetical protein	NA	NA	NA	NA
WP_002361363.1\|736151_736511_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002361364.1\|736638_737073_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002378095.1\|737090_737606_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	7.7e-39	49.1
WP_002378096.1\|737621_738797_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	5.1e-86	48.0

DBSCAN-SWA_2

1101215 : 1118986

Enterococcus_phage(42.86%)

holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002357859.1\|1101215_1103612_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
WP_002360497.1\|1103636_1103987_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002357857.1\|1104359_1104833_-	toxin	A0A097BY56	Enterococcus_phage	1.1e-60	71.2
WP_002361687.1\|1104879_1105362_-	helix-turn-helix transcriptional regulator	R9QTP6	Staphylococcus_phage	1.5e-20	48.6
WP_073459191.1\|1105530_1105713_+	hypothetical protein	NA	NA	NA	NA
WP_002401529.1\|1105838_1106513_+	DnaD domain protein	A0A1X9I617	Streptococcus_phage	9.5e-21	32.7
WP_002378242.1\|1106531_1107374_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	1.4e-29	30.3
WP_010706586.1\|1107376_1107469_+	hypothetical protein	NA	NA	NA	NA
WP_002388056.1\|1107461_1107833_+	hypothetical protein	NA	NA	NA	NA
WP_002360491.1\|1107852_1108260_+	transcriptional regulator	NA	NA	NA	NA
WP_010710173.1\|1108505_1108898_+	hypothetical protein	NA	NA	NA	NA
WP_002378245.1\|1108910_1109423_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	3.0e-35	49.4
WP_002377707.1\|1109455_1109815_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_002378246.1\|1109832_1110201_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	3.5e-09	39.7
WP_002401527.1\|1110190_1113124_+	hypothetical protein	A0A1U9WR55	Streptococcus_virus	2.8e-08	25.1
WP_002378247.1\|1113125_1114052_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	4.1e-147	78.6
WP_071981440.1\|1114064_1115522_+	hypothetical protein	C9E2K6	Enterococcus_phage	2.1e-174	47.4
WP_002378249.1\|1115554_1117324_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	1.2e-142	62.2
WP_002357842.1\|1117347_1117743_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_010710174.1\|1117888_1118986_+	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	1.5e-76	44.3

DBSCAN-SWA_3

1540448 : 1549092

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002366811.1\|1540448_1541021_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.1e-25	35.1
WP_002360140.1\|1541017_1542049_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	8.2e-56	44.4
WP_002401381.1\|1542050_1543490_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-49	33.2
WP_071981473.1\|1543465_1545685_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.8e-146	39.8
WP_002357272.1\|1545681_1546356_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|1546356_1546608_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002357270.1\|1546621_1547335_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
WP_002397378.1\|1547486_1548611_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002378405.1\|1548603_1549092_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.4e-19	42.0

DBSCAN-SWA_4

2209737 : 2219478

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002382497.1\|2209737_2211921_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	4.0e-286	66.8
WP_002356379.1\|2211953_2212550_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
WP_002362328.1\|2212594_2213713_-	DNA polymerase IV	NA	NA	NA	NA
WP_002356377.1\|2213838_2214597_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002378641.1\|2214580_2215243_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	8.8e-19	31.1
WP_002359438.1\|2215257_2216130_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-80	57.2
WP_002356372.1\|2216242_2216590_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_002356371.1\|2216582_2217422_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002384059.1\|2217538_2218489_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356367.1\|2218490_2218820_-	hypothetical protein	NA	NA	NA	NA
WP_002356366.1\|2218839_2219478_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018102

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection