CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP013311	Vibrio cholerae strain E1320 chromosome, complete genome	0 crisprs	DEDDh,DinG,csa3,cas3,WYL,csx1,RT	0	0	3	0
NZ_CP013312	Vibrio cholerae strain E1320 chromosome 2	0 crisprs	cas3,RT,PD-DExK,csa3	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

575274 : 582498

uncultured_Mediterranean_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000698379.1\|575274_576027_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.0e-69	53.3
WP_000002982.1\|576019_576646_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_000177568.1\|576645_577581_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000116737.1\|577654_578662_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_001894770.1\|578754_581343_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
WP_001279365.1\|581610_582498_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

DBSCAN-SWA_2

814127 : 821320

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000775253.1\|814127_815342_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
WP_000331703.1\|815378_815762_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_000301571.1\|815822_816146_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_001105747.1\|816194_816710_+	co-chaperone HscB	NA	NA	NA	NA
WP_001196560.1\|816733_818584_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
WP_001124187.1\|818597_818936_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_000872176.1\|818984_819179_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_000107237.1\|819398_820688_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
WP_001162850.1\|820891_821320_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_3

2430515 : 2437132

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864130.1\|2430515_2430986_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
WP_001122865.1\|2431250_2432360_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_000493874.1\|2432400_2433054_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001131994.1\|2433058_2434162_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
WP_000543544.1\|2434187_2434637_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_000366574.1\|2434736_2435987_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
WP_000210573.1\|2435998_2437132_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP013312

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

560173 : 630706

Vibrio_phage(81.48%)

integrase,capsid,head,tail,portal,transposase,terminase,plate,protease

attL 554249:554264|attR 567867:567882

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
554249:554264	attL	NA	NA	NA	NA
WP_000779169.1\|560173_561016_-	potassium channel family protein	A0A1B0Y2S3	Lactobacillus_phage	7.5e-07	44.0
WP_000251270.1\|561081_561630_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_001217709.1\|562287_563331_+	GMP reductase	A0A0N9Q9A5	Chrysochromulina_ericina_virus	1.8e-98	53.6
WP_000116330.1\|563463_564495_-\|integrase	tyrosine-type recombinase/integrase	A0A1S6L016	Salmonella_phage	1.1e-97	52.9
WP_000985033.1\|564494_564908_-	hypothetical protein	U3PDE6	Vibrio_phage	8.9e-70	100.0
WP_000132153.1\|564907_565813_-	NAD-dependent DNA ligase	U3PB51	Vibrio_phage	1.3e-161	100.0
WP_011929346.1\|565838_566486_-	phage repressor protein CI	A0A166YHA0	Vibrio_phage	8.7e-88	77.0
WP_000959026.1\|566634_566847_+	hypothetical protein	U3PFJ1	Vibrio_phage	6.4e-32	100.0
WP_000253094.1\|566957_567497_+	phage regulatory CII family protein	U3PIJ8	Vibrio_phage	1.0e-94	98.9
WP_001272765.1\|567509_567944_+	hypothetical protein	U3PDF0	Vibrio_phage	2.8e-74	100.0
567867:567882	attR	NA	NA	NA	NA
WP_001031153.1\|568025_568559_+	hypothetical protein	U3PB56	Vibrio_phage	1.6e-84	98.3
WP_000997543.1\|568555_568966_+	hypothetical protein	U3PCE8	Vibrio_phage	1.0e-70	93.4
WP_001198814.1\|569215_569443_+	hypothetical protein	U3PIK2	Vibrio_phage	3.2e-37	100.0
WP_000099608.1\|569439_570057_+	DNA methyltransferase	U3PDF3	Vibrio_phage	1.2e-118	100.0
WP_000629095.1\|570053_570164_+	hypothetical protein	NA	NA	NA	NA
WP_000613059.1\|570160_570745_+	hypothetical protein	U3PB60	Vibrio_phage	1.1e-102	97.4
WP_001094898.1\|570741_573303_+	replication endonuclease	A0A166YHE2	Vibrio_phage	0.0e+00	95.5
WP_000756239.1\|573312_573849_+	DUF262 domain-containing protein	U3PFK3	Vibrio_phage	4.1e-99	100.0
WP_001140410.1\|573922_574261_-	helix-turn-helix transcriptional regulator	Q8HA49	Vibrio_phage	2.1e-53	100.0
WP_001292394.1\|574498_574744_+	hypothetical protein	U3PDF9	Vibrio_phage	4.5e-37	98.8
WP_001263191.1\|574744_574996_-	ogr/Delta-like zinc finger family protein	U3PB63	Vibrio_phage	1.9e-43	100.0
WP_071919583.1\|575066_575552_-	type II toxin-antitoxin system YhaV family toxin	Q8HA46	Vibrio_phage	2.0e-89	98.8
WP_000521064.1\|575555_575750_-	hypothetical protein	Q8HA45	Vibrio_phage	5.1e-28	100.0
WP_000204987.1\|576205_576883_+	Bro-N domain-containing protein	Q8HA44	Vibrio_phage	1.8e-128	100.0
WP_053032059.1\|576879_577902_-\|portal	phage portal protein	U3PFK6	Vibrio_phage	4.9e-186	92.0
WP_000331804.1\|577898_579716_-\|terminase	terminase ATPase subunit family protein	U3PIL1	Vibrio_phage	0.0e+00	99.2
WP_001127096.1\|579889_580789_+\|capsid	GPO family capsid scaffolding protein	A0A160DHM4	Vibrio_phage	1.2e-122	99.7
WP_000078357.1\|580825_581848_+\|capsid	phage major capsid protein, P2 family	A0A160DHH1	Vibrio_phage	1.7e-186	96.4
WP_000059162.1\|581851_582568_+\|terminase	terminase endonuclease subunit	U3PCG2	Vibrio_phage	1.3e-124	93.3
WP_000494022.1\|582674_583136_+\|head	head completion/stabilization protein	U3PFL1	Vibrio_phage	5.8e-78	99.3
WP_000107425.1\|583132_583615_+\|tail	phage tail protein	U3PIL4	Vibrio_phage	4.4e-52	63.2
WP_000628619.1\|583611_584268_+	hypothetical protein	R9TPZ7	Vibrio_phage	9.6e-18	33.3
WP_000312536.1\|584269_585379_+	DUF2586 family protein	U3PB71	Vibrio_phage	1.0e-205	98.4
WP_000063627.1\|585378_585837_+	DUF2597 family protein	U3PCG7	Vibrio_phage	1.3e-82	100.0
WP_000382491.1\|585851_586061_+	TraR/DksA family transcriptional regulator	U3PFL5	Vibrio_phage	2.0e-33	100.0
WP_001077689.1\|586057_586285_+	hypothetical protein	U3PIL8	Vibrio_phage	2.1e-36	100.0
WP_000705018.1\|586271_586859_+	lysozyme	U3PDH1	Vibrio_phage	8.2e-77	67.7
WP_001113534.1\|586833_587175_+	hypothetical protein	U3PB75	Vibrio_phage	3.2e-49	95.6
WP_002034229.1\|587224_587386_+	hypothetical protein	A0A166YHN7	Vibrio_phage	1.4e-23	96.2
WP_000165783.1\|587382_587664_+	hypothetical protein	A0A160DHS7	Vibrio_phage	5.3e-34	76.3
WP_000343646.1\|587860_589678_+\|tail	phage tail tape measure protein	U3PFL8	Vibrio_phage	1.5e-249	75.9
WP_001113003.1\|589667_590000_+	DUF2590 family protein	U3PIM1	Vibrio_phage	1.7e-55	100.0
WP_000044511.1\|589996_591196_+\|plate	baseplate J/gp47 family protein	U3PDH5	Vibrio_phage	1.9e-221	99.2
WP_000005872.1\|591192_591852_+	hypothetical protein	U3PB79	Vibrio_phage	3.1e-125	99.5
WP_000083762.1\|591848_593687_+\|tail	phage tail protein	Q8HA52	Vibrio_phage	0.0e+00	100.0
WP_000369862.1\|593686_594211_+	hypothetical protein	Q8HA51	Vibrio_phage	9.1e-96	100.0
WP_000267790.1\|594213_595107_+	hypothetical protein	U3PIM3	Vibrio_phage	6.0e-156	97.0
WP_000457680.1\|595094_595568_+	hypothetical protein	U3PDI0	Vibrio_phage	1.1e-76	99.4
WP_000779004.1\|595564_597196_+	hypothetical protein	A0A160DHT6	Vibrio_phage	4.3e-309	97.4
WP_001883155.1\|598537_599689_+	DNA cytosine methyltransferase	A0A1P8CX13	Bacillus_phage	2.9e-25	26.3
WP_000762954.1\|599812_601729_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_000606740.1\|601721_602846_+	DUF3696 domain-containing protein	NA	NA	NA	NA
WP_000849740.1\|602842_603721_+	hypothetical protein	NA	NA	NA	NA
WP_000503164.1\|603788_604226_-\|transposase	IS200/IS605-like element IS1004 family transposase	Q331U4	Clostridium_botulinum_C_phage	1.9e-22	40.8
WP_079993097.1\|604357_604582_-	HNH endonuclease	NA	NA	NA	NA
WP_000507087.1\|604730_606086_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.7e-48	36.4
WP_000967516.1\|606275_607604_-	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_000400328.1\|607854_608685_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.4e-58	47.4
WP_000717524.1\|608787_609315_+	nicotinate-nicotinamide nucleotide adenylyltransferase	NA	NA	NA	NA
WP_000362857.1\|609581_611123_+	DUF3369 domain-containing protein	NA	NA	NA	NA
WP_000796029.1\|611180_613127_-	hypothetical protein	W8CYF6	Bacillus_phage	7.3e-05	23.3
WP_001267880.1\|613376_614351_+	hypothetical protein	NA	NA	NA	NA
WP_001046719.1\|614428_616009_-	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_001276502.1\|616412_617618_-	multidrug efflux MFS transporter EmrD	NA	NA	NA	NA
WP_000949610.1\|617870_618137_+	hypothetical protein	NA	NA	NA	NA
WP_000178906.1\|618127_619207_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	3.8e-19	32.8
WP_000746867.1\|619327_620584_-	thermolabile hemolysin	NA	NA	NA	NA
WP_001125273.1\|621553_623779_+	cytolysin VCC	NA	NA	NA	NA
WP_000586206.1\|624077_625724_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.3e-22	29.4
WP_001033424.1\|626071_627010_+	triacylglycerol lipase	NA	NA	NA	NA
WP_000717572.1\|627019_627874_+	lipase secretion chaperone	NA	NA	NA	NA
WP_000848953.1\|627949_630706_-\|protease	M6 family metalloprotease PrtV	NA	NA	NA	NA

DBSCAN-SWA_2

916373 : 929735

Vibrio_phage(55.56%)

coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000492997.1\|916373_916709_-	helix-turn-helix transcriptional regulator	A0A0N9HJE7	Vibrio_phage	4.7e-53	100.0
WP_000743997.1\|916840_917920_+	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000842207.1\|917921_918278_+	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000493022.1\|918413_918662_+	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
WP_071919593.1\|918768_919956_+\|coat	minor coat protein pIII	Q8LTP3	Vibrio_virus	4.1e-192	99.0
WP_000979342.1\|919952_920246_+	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
WP_071919594.1\|920242_921442_+	zonula occludens toxin ZOT	A0A142I6Z1	Vibrio_phage	1.0e-238	99.2
WP_071919595.1\|921541_922318_+	cholera enterotoxin catalytic subunit CtxA	A0A023W6A1	Vibrio_virus	9.9e-147	96.9
WP_044128129.1\|922314_922689_+	cholera enterotoxin binding subunit CtxB	D1GID8	Vibrio_virus	4.3e-63	97.6
WP_000492997.1\|923419_923755_-	helix-turn-helix transcriptional regulator	A0A0N9HJE7	Vibrio_phage	4.7e-53	100.0
WP_000743997.1\|923886_924966_+	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000842207.1\|924967_925324_+	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000493022.1\|925459_925708_+	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
WP_071919593.1\|925814_927002_+\|coat	minor coat protein pIII	Q8LTP3	Vibrio_virus	4.1e-192	99.0
WP_000979342.1\|926998_927292_+	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
WP_071919594.1\|927288_928488_+	zonula occludens toxin ZOT	A0A142I6Z1	Vibrio_phage	1.0e-238	99.2
WP_071919595.1\|928587_929364_+	cholera enterotoxin catalytic subunit CtxA	A0A023W6A1	Vibrio_virus	9.9e-147	96.9
WP_044128129.1\|929360_929735_+	cholera enterotoxin binding subunit CtxB	D1GID8	Vibrio_virus	4.3e-63	97.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP013311

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP013312

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection