CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP013308	Vibrio cholerae strain E506 chromosome 2	0 crisprs	PD-DExK,csa3,cas3	0	0	1	0
NZ_CP013307	Vibrio cholerae strain E506 chromosome 1, complete sequence	0 crisprs	csa3,DEDDh,cas3,WYL,DinG,csx1,RT	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

524878 : 529402

Satellite_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000743994.1\|524878_525958_+	replication initiation factor domain-containing protein	C9E7D5	Vibrio_virus	2.2e-213	100.0
WP_001911551.1\|525959_526310_+	hypothetical protein	U5TMH5	Satellite_phage	1.0e-63	100.0
WP_001888123.1\|526403_526628_+	RstC protein	U5TMI6	Satellite_phage	3.6e-33	94.6
WP_005521560.1\|526925_527117_-	hypothetical protein	NA	NA	NA	NA
WP_000743994.1\|527652_528732_+	replication initiation factor domain-containing protein	C9E7D5	Vibrio_virus	2.2e-213	100.0
WP_001911551.1\|528733_529084_+	hypothetical protein	U5TMH5	Satellite_phage	1.0e-63	100.0
WP_001888123.1\|529177_529402_+	RstC protein	U5TMI6	Satellite_phage	3.6e-33	94.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP013307

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

136123 : 143347

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000698379.1\|136123_136876_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.0e-69	53.3
WP_000002982.1\|136868_137495_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_000177568.1\|137494_138430_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000116737.1\|138503_139511_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_001895515.1\|139603_142192_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	2.2e-33	25.7
WP_001279365.1\|142459_143347_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

DBSCAN-SWA_2

374971 : 382164

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000775253.1\|374971_376186_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
WP_000331703.1\|376222_376606_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_000301571.1\|376666_376990_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_001105747.1\|377038_377554_+	co-chaperone HscB	NA	NA	NA	NA
WP_001196560.1\|377577_379428_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
WP_001124187.1\|379441_379780_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_000872176.1\|379828_380023_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_000107237.1\|380242_381532_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
WP_001162850.1\|381735_382164_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_3

1120278 : 1157094

Vibrio_phage(54.17%)

coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149591715.1\|1120278_1122384_-	RTX toxin T1SS ABC transporter subunit RtxB	W8CYL7	Bacillus_phage	4.9e-39	27.1
WP_001906284.1\|1122810_1123158_+	hypothetical protein	NA	NA	NA	NA
WP_001881196.1\|1123183_1123645_+	RTX toxin-activating lysine-acyltransferase RtxC	NA	NA	NA	NA
WP_001895450.1\|1123668_1137306_+	MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA	B3Y8K3	Vibrio_virus	8.4e-07	100.0
WP_000492997.1\|1138025_1138361_-	helix-turn-helix transcriptional regulator	A0A0N9HJE7	Vibrio_phage	4.7e-53	100.0
WP_019830347.1\|1138492_1139572_+	replication initiation factor domain-containing protein	A0A023W5Z8	Vibrio_virus	2.2e-213	100.0
WP_000842207.1\|1139573_1139930_+	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000493022.1\|1140065_1140314_+	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
WP_025997813.1\|1140420_1141608_+\|coat	minor coat protein pIII	A0A023W4K2	Vibrio_virus	1.8e-200	100.0
WP_000979342.1\|1141604_1141898_+	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
WP_050926705.1\|1141894_1143094_+	zonula occludens toxin ZOT	A0A023W604	Vibrio_virus	5.3e-240	100.0
WP_001888508.1\|1143193_1143970_+	cholera enterotoxin catalytic subunit CtxA	A0A023W6A1	Vibrio_virus	7.8e-152	100.0
WP_000593519.1\|1143966_1144341_+	cholera enterotoxin binding subunit CtxB	A0A142I6Y1	Vibrio_phage	5.9e-65	100.0
WP_000492997.1\|1144948_1145284_-	helix-turn-helix transcriptional regulator	A0A0N9HJE7	Vibrio_phage	4.7e-53	100.0
WP_019830347.1\|1145415_1146495_+	replication initiation factor domain-containing protein	A0A023W5Z8	Vibrio_virus	2.2e-213	100.0
WP_000842207.1\|1146496_1146853_+	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000493022.1\|1146988_1147237_+	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
WP_025997813.1\|1147343_1148531_+\|coat	minor coat protein pIII	A0A023W4K2	Vibrio_virus	1.8e-200	100.0
WP_000979342.1\|1148527_1148821_+	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
WP_050926705.1\|1148817_1150017_+	zonula occludens toxin ZOT	A0A023W604	Vibrio_virus	5.3e-240	100.0
WP_001888508.1\|1150116_1150893_+	cholera enterotoxin catalytic subunit CtxA	A0A023W6A1	Vibrio_virus	7.8e-152	100.0
WP_145976653.1\|1150905_1151265_+	cholera enterotoxin binding subunit CtxB	A0A142I6Y1	Vibrio_phage	1.9e-60	100.0
WP_000170634.1\|1151498_1152083_-	DNA-binding protein	E3U9I9	Vibrio_phage	6.4e-114	100.0
WP_001161489.1\|1152075_1152243_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0
WP_001052672.1\|1152320_1153013_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000512956.1\|1153142_1153412_-	hypothetical protein	NA	NA	NA	NA
WP_001881266.1\|1153431_1155000_-	replication protein	A7BJY2	Enterobacteria_phage	2.7e-58	32.3
WP_000005769.1\|1155176_1155728_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001161489.1\|1156926_1157094_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0

DBSCAN-SWA_4

2002760 : 2009377

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864130.1\|2002760_2003231_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
WP_001122865.1\|2003495_2004605_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_000493874.1\|2004645_2005299_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001131994.1\|2005303_2006407_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
WP_000543544.1\|2006432_2006882_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_000366574.1\|2006981_2008232_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
WP_000210573.1\|2008243_2009377_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

DBSCAN-SWA_5

2374361 : 2419056

Vibrio_phage(93.18%)

tRNA,plate,transposase,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000042615.1\|2374361_2375378_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000835873.1\|2375505_2376186_-	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_000651337.1\|2376205_2376880_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_000744680.1\|2377006_2377840_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S6L1V5	Vibrio_phage	8.9e-69	49.6
WP_000050198.1\|2377909_2379385_-	AAA family ATPase	NA	NA	NA	NA
WP_000439805.1\|2379439_2380525_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_000818616.1\|2380552_2381077_-	shikimate kinase AroK	NA	NA	NA	NA
WP_000788426.1\|2381263_2382979_-	type IV pilus secretin PilQ family protein	O80264	Vibrio_phage	3.1e-15	22.9
WP_000792032.1\|2383004_2383523_-	pilus assembly protein PilP	NA	NA	NA	NA
WP_000157690.1\|2383512_2384103_-	type 4a pilus biogenesis protein PilO	NA	NA	NA	NA
WP_000902745.1\|2384095_2384680_-	PilN domain-containing protein	NA	NA	NA	NA
WP_000959485.1\|2384669_2385128_-	type IV pilus assembly protein PilM	NA	NA	NA	NA
WP_000005494.1\|2385417_2386155_-	transcriptional regulator	A0A2I7S9A5	Vibrio_phage	1.4e-81	61.3
WP_000373567.1\|2386307_2386532_+	helix-turn-helix domain-containing protein	M1PVU4	Vibrio_phage	2.3e-16	61.9
WP_001895336.1\|2386543_2388547_+\|transposase	Mu transposase C-terminal domain-containing protein	A0A2I7S9A8	Vibrio_phage	2.2e-275	69.8
WP_000800334.1\|2388573_2389518_+	AAA family ATPase	M4M9P4	Vibrio_phage	1.1e-126	73.7
WP_000157299.1\|2389525_2389750_+	hypothetical protein	NA	NA	NA	NA
WP_001216028.1\|2389759_2390329_+	hypothetical protein	NA	NA	NA	NA
WP_001032752.1\|2390338_2390713_+	hypothetical protein	M4MB90	Vibrio_phage	2.9e-27	59.0
WP_001192102.1\|2390862_2391477_+	DUF3164 family protein	M4MHH7	Vibrio_phage	2.0e-86	79.6
WP_000512064.1\|2391486_2391759_+	hypothetical protein	A0A2I7S9G2	Vibrio_phage	2.9e-21	61.2
WP_000551393.1\|2391751_2391994_+	hypothetical protein	M4MCS5	Vibrio_phage	4.2e-19	62.0
WP_000413231.1\|2391977_2392175_+	hypothetical protein	NA	NA	NA	NA
WP_001895326.1\|2392327_2392522_+	hypothetical protein	NA	NA	NA	NA
WP_000856884.1\|2392524_2392794_+	DUF3850 domain-containing protein	C1KFE1	Lactobacillus_virus	2.5e-12	47.6
WP_000762331.1\|2392790_2393321_+	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	2.2e-28	42.9
WP_000466681.1\|2393400_2393634_+	hypothetical protein	M4M9N5	Vibrio_phage	4.1e-24	66.2
WP_000404914.1\|2393636_2393915_+	hypothetical protein	NA	NA	NA	NA
WP_000040562.1\|2393927_2394473_+	regulatory protein GemA	A0A2I7S9B8	Vibrio_phage	4.5e-53	58.2
WP_000837433.1\|2394462_2394909_+	hypothetical protein	NA	NA	NA	NA
WP_001029055.1\|2394987_2395404_+	hypothetical protein	M4MHG9	Vibrio_phage	6.3e-31	50.0
WP_000493682.1\|2395488_2396046_+	hypothetical protein	A0A2I7S9B9	Vibrio_phage	1.8e-70	72.1
WP_001120998.1\|2396308_2396908_+	hypothetical protein	M1NVP4	Vibrio_phage	5.8e-46	57.3
WP_001281317.1\|2396904_2397135_+	TraR/DksA C4-type zinc finger protein	M4MHG5	Vibrio_phage	8.8e-19	63.2
WP_000362983.1\|2397134_2397434_+	DUF2730 family protein	M1Q558	Vibrio_phage	1.1e-29	70.0
WP_000008606.1\|2397442_2397733_+	hypothetical protein	A0A2I7S9D8	Vibrio_phage	3.9e-40	82.3
WP_001195537.1\|2397744_2398311_+	DUF3486 family protein	M4MCR3	Vibrio_phage	3.2e-46	55.0
WP_001105344.1\|2398311_2399877_+	hypothetical protein	M4MHG0	Vibrio_phage	4.5e-231	78.0
WP_000027033.1\|2399873_2401433_+	DUF935 domain-containing protein	M4M9P3	Vibrio_phage	3.5e-228	76.1
WP_001895334.1\|2401425_2402199_+	hypothetical protein	M1PVV7	Vibrio_phage	1.3e-114	75.5
WP_000246042.1\|2402210_2402459_+	hypothetical protein	NA	NA	NA	NA
WP_000638754.1\|2402455_2402968_+	hypothetical protein	A0A0F6N5P8	Escherichia_phage	5.3e-32	45.6
WP_000638762.1\|2402964_2403600_+	hypothetical protein	A0A1V0E8A2	Vibrio_phage	1.7e-40	47.3
WP_001249579.1\|2403599_2403884_+	hypothetical protein	NA	NA	NA	NA
WP_001262460.1\|2404216_2405173_+	hypothetical protein	M1Q578	Vibrio_phage	4.7e-98	59.8
WP_001218331.1\|2405175_2406075_+\|head	Mu-like prophage major head subunit gpT family protein	M4MB71	Vibrio_phage	2.6e-146	81.4
WP_000004756.1\|2406163_2406739_+	hypothetical protein	M4M9M3	Vibrio_phage	4.0e-20	54.5
WP_001029276.1\|2406744_2407179_+	DUF1320 domain-containing protein	A0A2I7S9E9	Vibrio_phage	9.6e-67	88.2
WP_000513061.1\|2407178_2407721_+	phage virion morphogenesis protein	A0A2I7S9D7	Vibrio_phage	3.3e-72	74.9
WP_000100991.1\|2407717_2408317_+	hypothetical protein	M4MHF0	Vibrio_phage	6.4e-69	61.2
WP_000437435.1\|2408330_2408531_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_001128141.1\|2408533_2410018_+\|tail	phage tail sheath subtilisin-like domain-containing protein	M1Q565	Vibrio_phage	1.5e-207	72.3
WP_001895328.1\|2410032_2410386_+\|tail	phage tail tube protein	A0A2I7S9D5	Vibrio_phage	7.9e-43	69.2
WP_000996598.1\|2410385_2410745_+\|tail	phage tail assembly protein	A0A2I7S9E0	Vibrio_phage	5.0e-37	64.1
WP_162493705.1\|2410951_2412574_+	tape measure protein	A0A2I7S9D9	Vibrio_phage	6.0e-138	52.6
WP_000863380.1\|2412585_2413905_+	DNA circularization N-terminal domain-containing protein	A0A2I7S9E8	Vibrio_phage	5.0e-167	68.0
WP_001286435.1\|2413897_2414977_+	hypothetical protein	M4M9L5	Vibrio_phage	3.0e-157	75.4
WP_170826454.1\|2414970_2415588_+\|plate	phage baseplate assembly protein V	M4MCP6	Vibrio_phage	4.0e-74	70.2
WP_000095018.1\|2415590_2416040_+	phage GP46 family protein	M4MB61	Vibrio_phage	1.1e-54	73.6
WP_001147110.1\|2416029_2417097_+\|plate	baseplate J/gp47 family protein	A0A2I7S9E5	Vibrio_phage	1.6e-147	72.1
WP_000510163.1\|2417081_2417669_+	DUF2313 domain-containing protein	A0A2I7S9L6	Vibrio_phage	2.1e-93	79.5
WP_001895339.1\|2417668_2418520_+	hypothetical protein	Q8HA52	Vibrio_phage	1.9e-42	60.4
WP_001065600.1\|2418519_2419056_+	hypothetical protein	H9C146	Vibrio_phage	6.8e-30	58.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP013308

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP013307

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection