CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP015113	Kosakonia radicincitans strain GXGL-4A chromosome, complete genome	2 crisprs	cas3,DEDDh,WYL,csa3,DinG	0	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015113_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015113_1

2234701-2234786

Orphan

Consensus_repeat	Method
GCAGCCTGTGCTTTCTGCTCTAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015113_1

>merge|NZ_CP015113|1|2234701-2234786|CRISPRCasFinder
GCAGCCTGTGCTTTCTGCTCTACTGCCGGTTTAGCTGCTTTTTTGTGATGTTTTTTCACTTTTGCAGCCTGAGCTTTCTGCTCTAC

>NZ_CP015113|1|1|2234701-2234786|CRISPRCasFinder
GCAGCCTGTGCTTTCTGCTCTAC	TGCCGGTTTAGCTGCTTTTTTGTGATGTTTTTTCACTTTT
GCAGCCTGAGCTTTCTGCTCTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015113.1\|WP_071920732.1\|2231372_2233535_+\|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl\|CDD\|238923
NZ_CP015113.1\|WP_007374880.1\|2242515_2243163_-\|osmoprotectant-ABC-transporter-permease-OsmW	unknown	unknown	gnl\|CDD\|224095
NZ_CP015113.1\|WP_071920731.1\|2229933_2230152_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274112
NZ_CP015113.1\|WP_007374870.1\|2230936_2231266_+\|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtI	unknown	unknown	gnl\|CDD\|182618
NZ_CP015113.1\|WP_007374876.1\|2238274_2239171_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176106
NZ_CP015113.1\|WP_074989315.1\|2228857_2229940_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP015113.1\|WP_007374872.1\|2233536_2234364_-\|serine-protease	unknown	unknown	gnl\|CDD\|226119
NZ_CP015113.1\|WP_035885801.1\|2228026_2228461_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015113.1\|WP_035885796.1\|2236904_2238155_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP015113.1\|WP_007374877.1\|2239300_2240521_+\|ROK-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224851
NZ_CP015113.1\|WP_071532063.1\|2226128_2226548_+\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl\|CDD\|182350
NZ_CP015113.1\|WP_071920734.1\|2241370_2242516_-\|osmoprotectant-ABC-transporter-ATP-binding-protein-OsmV	unknown	unknown	gnl\|CDD\|224050
NZ_CP015113.1\|WP_007374869.1\|2230596_2230950_+\|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtJ	unknown	unknown	gnl\|CDD\|182471
NZ_CP015113.1\|WP_071920733.1\|2235133_2236618_-\|carboxypeptidase-M32	unknown	unknown	gnl\|CDD\|341054
NZ_CP015113.1\|WP_071920736.1\|2244095_2244806_-\|osmoprotectant-ABC-transporter-permease-OsmY	unknown	unknown	gnl\|CDD\|224095
NZ_CP015113.1\|WP_071920729.1\|2224700_2225684_+\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187540
NZ_CP015113.1\|WP_071920737.1\|2245092_2245704_-\|Tat-proofreading-chaperone-DmsD	unknown	unknown	gnl\|CDD\|236938
NZ_CP015113.1\|WP_007374864.1\|2226550_2227813_+\|translesion-error-prone-DNA-polymerase-V-subunit-UmuC	unknown	unknown	gnl\|CDD\|179607
NZ_CP015113.1\|WP_007374878.1\|2240646_2241342_+\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|237083
NZ_CP015113.1\|WP_071920735.1\|2243172_2244075_-\|osmoprotectant-ABC-transporter-substrate-binding-protein-OsmX	unknown	unknown	gnl\|CDD\|270329

Protein	Function_ID	Function_description	E-value
NZ_CP015113.1\|WP_071920732.1\|2231372_2233535_+\|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.86207e-96
NZ_CP015113.1\|WP_007374880.1\|2242515_2243163_-\|osmoprotectant-ABC-transporter-permease-OsmW	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	1.67816e-73
NZ_CP015113.1\|WP_007374870.1\|2230936_2231266_+\|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtI	gnl\|CDD\|182618	PRK10650, PRK10650, multidrug/spermidine efflux SMR transporter subunit MdtI.	2.80965e-53
NZ_CP015113.1\|WP_007374876.1\|2238274_2239171_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.53802e-64
NZ_CP015113.1\|WP_074989315.1\|2228857_2229940_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	1.28515e-41
NZ_CP015113.1\|WP_007374872.1\|2233536_2234364_-\|serine-protease	gnl\|CDD\|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	9.04563e-77
NZ_CP015113.1\|WP_071920731.1\|2229933_2230152_-\|hypothetical-protein	gnl\|CDD\|274112	TIGR02400, Alphaalpha-trehalose-phosphate_synthase, alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., ). [Cellular processes, Adaptations to atypical conditions].	2.79972e-06
NZ_CP015113.1\|WP_035885796.1\|2236904_2238155_-\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.48954e-83
NZ_CP015113.1\|WP_007374877.1\|2239300_2240521_+\|ROK-family-transcriptional-regulator	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.15943e-69
NZ_CP015113.1\|WP_071532063.1\|2226128_2226548_+\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl\|CDD\|182350	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit.	2.11979e-65
NZ_CP015113.1\|WP_071920734.1\|2241370_2242516_-\|osmoprotectant-ABC-transporter-ATP-binding-protein-OsmV	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	6.51047e-166
NZ_CP015113.1\|WP_007374869.1\|2230596_2230950_+\|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtJ	gnl\|CDD\|182471	PRK10452, PRK10452, multidrug/spermidine efflux SMR transporter subunit MdtJ.	2.40743e-56
NZ_CP015113.1\|WP_071920733.1\|2235133_2236618_-\|carboxypeptidase-M32	gnl\|CDD\|341054	cd06460, M32_Taq, Peptidase family M32, which includes thermostable carboxypeptidases TaqCP, PfuCP and FisCP. Peptidase family M32 is a subclass of metallocarboxypeptidases, distributed mainly in bacteria and archaea, whose members contain a HEXXH motif that participates in coordinating a divalent cation such as Zn2+ or Co2+. It includes the thermostable carboxypeptidases (E.C. 3.4.17.19) from Thermus aquaticus (TaqCP) and Pyrococcus furiosus (PfuCP), which have broad specificities toward a wide range of C-terminal substrates that include basic, aromatic, neutral and polar amino acids. These enzymes have a similar fold to the M3 peptidases such as neurolysin and the M2 angiotensin converting enzyme (ACE). The keratin-degrading extremophilic eubacterium Fervidobacterium islandicum M32 carboxypeptidase (FisCP) plays an important role in cellular metabolism, and significantly enhances the degradation of native chicken feathers. It has been shown to mainly cleave the C-termini of peptides with a basic amino acid sequence. Novel M32 peptidases from some eukaryotes: protozoa Trypanosoma cruzi, a causative agent of Chagas' disease, and Leishmania major, a parasite that causes leishmaniasis, have been identified, thus making these enzymes an attractive potential target for drug development against these organisms.	0
NZ_CP015113.1\|WP_071920736.1\|2244095_2244806_-\|osmoprotectant-ABC-transporter-permease-OsmY	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	4.11439e-69
NZ_CP015113.1\|WP_071920729.1\|2224700_2225684_+\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187540	cd05229, SDR_a3, atypical (a) SDRs, subgroup 3. These atypical SDR family members of unknown function have a glycine-rich NAD(P)-binding motif consensus that is very similar to the extended SDRs, GXXGXXG. Generally, this group has poor conservation of the active site tetrad, However, individual sequences do contain matches to the YXXXK active site motif, and generally Tyr or Asn in place of the upstream Ser found in most SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.53772e-107
NZ_CP015113.1\|WP_071920737.1\|2245092_2245704_-\|Tat-proofreading-chaperone-DmsD	gnl\|CDD\|236938	PRK11621, PRK11621, Tat proofreading chaperone DmsD.	9.00343e-106
NZ_CP015113.1\|WP_007374864.1\|2226550_2227813_+\|translesion-error-prone-DNA-polymerase-V-subunit-UmuC	gnl\|CDD\|179607	PRK03609, umuC, translesion error-prone DNA polymerase V subunit UmuC.	0
NZ_CP015113.1\|WP_007374878.1\|2240646_2241342_+\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|237083	PRK12374, PRK12374, ATP-dependent dethiobiotin synthetase BioD.	4.63773e-160
NZ_CP015113.1\|WP_071920735.1\|2243172_2244075_-\|osmoprotectant-ABC-transporter-substrate-binding-protein-OsmX	gnl\|CDD\|270329	cd13611, PBP2_YehZ, Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein YehZ of Clostridium sticklandii is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. YehZ belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.58845e-140

>NZ_CP015113.1|WP_007374872.1|2233536_2234364_-|serine-protease
MRKTVVLMLGSLFLFSAAGHADDGEDDAVNARDVKTLFFGHDDRVPVPTPTKAPWDAIGQLETASGNLCTATLISPHLALTAGHCLLTPPNGKADKAVALRFVSQKGTWRYEIHGIEGRVDASLGHRLKPDGDGWIVPSSAASWDFGLIVLRYPPSGITPLPIFVGDKDELTAALKTANRKVTQAGYPEDHLDTLYSHQDCTVTGWAQSSVLSHQCDTLPGDSGSPLMLKTDAGWQLIAVQSSAPAAKDRWRADNRAISVTGFRDKLEALAKESE
>NZ_CP015113.1|WP_071920732.1|2231372_2233535_+|bifunctional-diguanylate-cyclase/phosphodiesterase
MFNPFSWRNIPGARTLFVMTFMAGIGLIVSVVALLYLSLNLISSKANEIDEHRTALAVQGAIQTSVNRIRSLVIDNGVWDDAVREVYRPQLDTQWLYNTWGAGYKINNLYDGTFVLDEQFNVLWGAFRSQLFTERDLTFFGSGLRALIRGHNQLLQSGKEVYAGITQTRDGVAFISIGLVRPMVGRLEVYDGTRRYLVITRHLDAQILSDLGKTFQITDLRLSPQKTAASSVPLRDSAGEELGYLSWTPRLPGAEAARAAASNIRQIAMLASGLILLFIVLSSAGLYKLARGERLARKIALTDWLSRLPNRRALIENIEKLGAMGDLDTISVVFIDLDGFKDVNDIYGHDVGDRLIVTIAQTLREKVPTDGMLARMGGDEFAMTLSGPWSVEKATDFANNVLQYLNHPVRIGKRTIHIGASIGIASGTLLECSSSELFRRADIAMYHSKITGKDRLTHYDAALNSARERQLLIESDIRDGLEREEFDVWYQPIVDARSQMMVGIEALARWPRRPAGELKPDEFIPIAETSGLIYSLGQFVLRRACSDLQPIEDLKLSVNISPAQFRDPEFENKVSSVLETCRFPAHRLQLEVTETYVLENPERARSAIANLKALGTAVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDDDEQASALVSGTIRIASALGMQVVAEGVENEKQMKLLRLAGCDQLQGYYFSEPMPLHDILQLRLQRLG
>NZ_CP015113.1|WP_007374870.1|2230936_2231266_+|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtI
MQPFEWIHALWLAMAIGLEIVANIFLKFSDGFRRKLYGCGSLLAVLAAFSALSQAVKGIDLSVAYALWGGFGIVATLAAGWILFGQRLNRKGWFGLLLLIMGMLLIKLA
>NZ_CP015113.1|WP_007374869.1|2230596_2230950_+|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtJ
MIYWILLILAIVAEITGTLSMKWASVNDSQTGFILMLAMIALSYIFLSFAVKKIALGVAYAMWEGIGILFITLFSVFLFDEQLPVLKVIGLATLVLGIVLIKSGTRKPRQERNHAAV
>NZ_CP015113.1|WP_071920731.1|2229933_2230152_-|hypothetical-protein
MSRCQSRGHSWEMAPNEYDNVYHVYVHRVLWPVFHNRPDLARYQKAGVITYKTCTRKVACTLYGIFAAQRLY
>NZ_CP015113.1|WP_074989315.1|2228857_2229940_+|AI-2E-family-transporter
MSTLKSNQFFFIILLLLVSVAFFGLIQPYYSAIIWAIILALIFYPLRMRLSVWLHGRNGIASLITVLLICVIVFIPMMMVLSSLAVEINSLYQRLQNNATDLPQLLSNGIAHLPDWAKGYLRDNDFDSVNAIREKLSGVALSVGRYLAGSAVIIGKGTLGITVSFCLMVYLLFFLLKDGATLVRQIYEVMPLTATIKRRLFLKFAGVARATVKGTLVVAIVQGALGGIGFWFAGFNGSLLWAALMAFLSLIPAVGTAIVWIPAVIFLYSTDEFVTATVLTLYFVIVVGLADNLLRPLLVGKDTRMPDYLILLTTLGGLQFFGINGFVLGPMIAALFITSWNLLAEARASVAKNSPPTPPQ
>NZ_CP015113.1|WP_035885801.1|2228026_2228461_-|hypothetical-protein
MTIVMLMSTDADIVNTQLNAAWNPITNRYTWAQVSSMNLNIINGATIVVIAHGNGTEIGNAAPGVVDVNAETFLALVQGNMANNAVPARIYISSCGPGIAEFAANVRIAAQNNQIWHNTRIFGHSDPVSGPVPPANDIRWTRIF
>NZ_CP015113.1|WP_007374864.1|2226550_2227813_+|translesion-error-prone-DNA-polymerase-V-subunit-UmuC
MFALADVNSFYTSCETVFRPDLKGKPVVVVSNNDGCVISRSAEAKALGIAMGEPFFKLKNKTFSSEVHVFSSNYALYADLSARVMQTLTQMAPAIEIYSIDEAFIDLSGIASYMSLTDFGKAVRNQVLKNTGLTIGIGVSQTKTLAKLANYATKRWASAGGVVDLSDISRQRKLLERVPVEDVWGVGRRISKKLNNMGINTALDLANSSPWVIKKHFNVVLERTLRELRGESCLELEEFVPDKQQIMFSRSFGYRITEYADMRQAVCAYAERAAAKLRSEHQFCAFVSVFLRTSPHADNEIYYENQSSTKLSIPSNDTRDIIRASTESLDRIWVDGYRYMKAGVMLADFFSRGTAQLNLFDDTAPKANSTALMAVIDGINSSGKGKVWFAGQGIQKPWAMKREMLSPSYTTRYSDLPVAK
>NZ_CP015113.1|WP_071532063.1|2226128_2226548_+|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MQLFYPLEIAPSIHLPLFTERVPCGFPGPAQDYVEDRLDLNTLLIAHPCATYFIKVSGDSMTGAGIGDGDLLVVDRSLSASHGDIVIAAVAGEFTVKELRTHPVLRLVPHNSNYSPITFHNPEDLEIFGVVTFSVKSHK
>NZ_CP015113.1|WP_071920729.1|2224700_2225684_+|NAD-dependent-epimerase/dehydratase-family-protein
MKNRNKVLVLGATGGIGGEIARKLIREKWDVHALRRSAPQNEEPANMPWITGDALNAEQVAAAASECSVIVHAVNPPGYRNWEQLVLPMLQNTINAAERNGALIVLPGTVYNYGPDAFPLLREDSPQNPVTRKGAIRVQMEKALNAYTQRGGKVLILRAGDFFGPDAGNNWFSQGWITPGKLPRTIKNPGKAGTGHQWAYLPDVAETLSALLARREQLEPFACFHMRGHWDADGTAMAAAIKSVAQFAGIKAKITSFPWWLIFAMAPFNTTLREMREMRYLWEQPIQMDNAKLIDFLGHEPHTPLIEAVRTTLIGQGCINHASFTRL
>NZ_CP015113.1|WP_071920733.1|2235133_2236618_-|carboxypeptidase-M32
MDKQNYQQLTRTFQRLSRFSHLSAIASWDMFTMMPPGGSAARGEALAELSVLQHQILTDKRVGQWLQAAKQETLDDIEQANLREMTRHYQQAALLPEALVEAQSLAGSKCEHAWRTQRPANDWAGFSANLKEVVKLAREEASLRAAAKGCSPYDALLDKFEPDMTSARLDELFGEVKSWLPDLLNRAVAKQAQQTLIAPQGPFPQAVQRELGLQAMQVLGFDFNGGRLDVSAHPFCGGVPEDVRITTRYDENELLSALFGVVHETGHARYEQNLPRAWAGQPIALARSTAIHESQSLFFEMQLGRSDAFLRRLQPAIVESFGMQPAFEEGNFIAWNQRVKPGYIRVEADEVSYPAHVILRYEIERALIDGDIEVEDIPALWNEKMQAWLGLSTEGNYRNGCMQDIHWTDGGFGYFPSYTLGAMYAAQLFHAARVALPTLDEAIAQGDFSALFDWLRQNIWQHGSRFSTSQLIENATGEALNADYFRQHLTRRYL
>NZ_CP015113.1|WP_035885796.1|2236904_2238155_-|MFS-transporter
MSRTTTVDTEPASVVNEIPVALPGQFIKRGTPQFMRVTLALFSAGLATFALLYCVQPILPVLSHEFGVSPASSSISLSISTAMLAIGLLFTGPLSDAIGRKKVMVTALLLASCCTLLSTMMTSWHGILVMRALLGLSLSGVAAVGMTYLSEEIHPSFVAFSMGLYISGNSIGGMSGRLISGVFTDFFNWRIAVAVIGCFALASALMFWKILPESRHFRPTSLRPKTLLINLHLHLRDKGLPLLFLEGFLLMGSFVTLFNYIGYRLMLSPWSLSQAAVGLLSLAYLTGTWSSPRAGAMTSKYGRGPVMIGSSAIMLFGLLLTLFSSLWLIFPGMLLFTAGFFAAHAVASSWIGPRARRAKGQASSLYLFSYYLGSSVAGTLGGVFWHSYGWNGVGGFIALMLLIAILVGSRIHSRLH
>NZ_CP015113.1|WP_007374876.1|2238274_2239171_+|LysR-family-transcriptional-regulator
MNIELRHLRYFIAVAEELHFGHAAARLNISQPPLSQQIQLLEQQVGARLLARTNRSVALTAAGKQFLADSRQILGLVDEAAARAARLHQGETGELRIGFTSSAPFIKAVSDTLSSFRQRYPDVHIQTREINTREQIAPLNEGSLDLGLMRNTPLPETLAWEVILREPLLAMIHRDHPLAARKAVSLKELAQEPFVFFDPHVGTGLYDEILGLMRRYQLIPTITQEVGEAMTIIGLVAAGLGVSILPASFHRVQLNEIRWVPIIEADAVSEMWLVWAKHHEQGTAAARFKQQLLHAAIG
>NZ_CP015113.1|WP_007374877.1|2239300_2240521_+|ROK-family-transcriptional-regulator
MVADSQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAPASITKIVREMLEAHLVQETEIQEPGSRGRPAVGLVVETEAWHYLSLRISRGEIFLSLRDLSSKLVVEDRLELPLGDEMPLLDRIIHLIDSFFTRHQNRLERLTSIAITLPGIIDTENGIVHRMPFYTEVKDMPLGETLEKHTGVPVYVQHDISAWTMAEALFGASRGARDVIQVVIDHNVGAGVITDGRLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVESVLELAQLRMSQSMSSMLHQKPLTVEWLCQAAQQGDLLAKDIISGVGANIGRILAIMVNLFNPQKILIGSPLSKAADILFPAIADCIRQQALPAYSQHISVESTQFTNQGTMAGAALVKDAMYNGSLLIRLLQG
>NZ_CP015113.1|WP_007374878.1|2240646_2241342_+|ATP-dependent-dethiobiotin-synthetase-BioD
MLKRFFVTGTDTSVGKTVASRALLQALAASGKTVAGYKPVAKGSKETPEGLRNKDALVLQSVSSLDLPYQAINPIALSEEESSVAHSCPINYSLLSNGLVNLCEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQMAVVMVVGIQEGCINHALLTAQAIASDGLPLIGWVANRINPGLAHYAEIINVLSKKLPAPLVGELPYLPRAEQRDLAQYINLQMATGMLVADRILA
>NZ_CP015113.1|WP_071920734.1|2241370_2242516_-|osmoprotectant-ABC-transporter-ATP-binding-protein-OsmV
MIKLENLTKQFTQKNGQTVKAVDNVNLTVPEGEMCVLLGPSGCGKTTTLKMINRLIAPSSGSIFINGEDTSAMDTVTLRRNIGYVIQQIGLFPNMTIEENITVVPRMLGWDKARCKSRAEELMEMVALDAKKFLHRYPREMSGGQQQRIGVIRALAADPPVLLMDEPFGAVDPINREVIQNQFLEMQRKLKKTVMLVSHDIDEALKLGDRIAVFRQGRIVQCASPDELLAKPANEFVGSFVGQDRTLKRLLLVSAGDVTDQQPTITVRESTPAAEAFATMDDNDIRAITVVDSAGKPLGFVKRREARNAPGSCSDLLHPFRITGKAEDNLRVVLSRLYESNTSWMPIVDEDGRYNGEISQDYIAEYLSSGRTRRVLNIHDV
>NZ_CP015113.1|WP_007374880.1|2242515_2243163_-|osmoprotectant-ABC-transporter-permease-OsmW
METIHYMMDNAGYLASLTFQHLWLVLLAVGLAIIIGVPLGILIVRHKWLATPVLGLATLVLTIPSIALFGLMIPLFSLIGQGIGALPAITAVFLYSLLPIVRNTHTALDSLPPGLREAGRGIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIAAVIGAGGLGLLLLNGIGGSDIRMLIAGALMICVLAIVLDWLLHRLQIVLTPKGIR
>NZ_CP015113.1|WP_071920735.1|2243172_2244075_-|osmoprotectant-ABC-transporter-substrate-binding-protein-OsmX
MKRLTRLLGVLAAAVLFSASAHAAPLILATKSFTEQHILSAMTVQYLQKRGFQVQPQTNIATVISRNAMINKQIDMTWEYTGTSLIIFNHINQRMSPQESYDTVKRLDAKHGLVWLKPANMNNTYAFAMQRKRAEAEHITTMSQMVAKIEQIRKTDPKHNWLLGLDLEFAGRSDGMKPLQQAYGMALDRPQIRQMDPGLVYNAIRDGFVDAGLVYTTDGRVKGFDLKVLEDDKGFFPSYAVTPVVREDTLKANPGLEEALNTLSGLLNNDVIMTLNAKVDIDHQTPQQVAHDFLHEKGLL
>NZ_CP015113.1|WP_071920736.1|2244095_2244806_-|osmoprotectant-ABC-transporter-permease-OsmY
MQLSVLARALLFIVGIAIVLALLTWGIGLDTLKARQVDLLYLGQQHLILVFSSMFFALLVGIPSGIALSRPAARGVAEYVMQIFNVGNTLPPLAVLALAMVVIGIGDTPAIIALFLASLLPIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVEIPNAMPVILSGVRIATAINVGTAPLAFLIGASSYGELIFPGIYLNDFPTLILGAAATALFALILDTLLAALGRFLSPHTA
>NZ_CP015113.1|WP_071920737.1|2245092_2245704_-|Tat-proofreading-chaperone-DmsD
MTDLTGENFVVTARVLGALFYYPPQSEQCQPLIAAFTQGDWAKQWPLPQTDLAPLVAEFAAPCDEPLSAAWQRLFIGPWALPAPPWGSVWLDKESVLFGDSTLALRQWMRENNIAFDSRQNEPEDHFGALLLLAAWLAEEGNSDACERLLAWHLLPWAGRFLTVFTNEAQHPFWCSVGKLAQLTLASWQSRLLIPVAQKPLFR

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Crispr_ID: NZ_CP015113_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015113_2

4526628-4526788

Orphan

Consensus_repeat	Method
AGTCCGGATTCCGGACTC	CRT

3 spacers

The CRISPR arrays of NZ_CP015113_2

>merge|NZ_CP015113|2|4526628-4526788|CRT
AGTCCGGATTCCGGACTCCGGTGTAACCCGTTGATTTCATGCTAAGTCCTGATTCCGGACTCAGTGTTTTATCCGCTGACGGGGTACTGAGTCCGTTTTCCGGACTCAGTGATTCCGGGGTATTTTGGGTGCTTTTTTGACTGAGTCCGGATTCCGGACTC

>NZ_CP015113|2|1|4526628-4526788|CRT
AGTCCGGATTCCGGACTC	CGGTGTAACCCGTTGATTTCATGCTA
AGTCCTGATTCCGGACTC	AGTGTTTTATCCGCTGACGGGGTACTG
AGTCCGTTTTCCGGACTC	AGTGATTCCGGGGTATTTTGGGTGCTTTTTTGACTG
AGTCCGGATTCCGGACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015113.1\|WP_071921507.1\|4533912_4534836_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176166
NZ_CP015113.1\|WP_071921495.1\|4521979_4522474_-\|DUF3577-domain-containing-protein	unknown	unknown	gnl\|CDD\|371899
NZ_CP015113.1\|WP_071921488.1\|4517854_4519147_-\|TcpQ-domain-containing-protein	unknown	unknown	gnl\|CDD\|163460
NZ_CP015113.1\|WP_071921496.1\|4523112_4525125_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP015113.1\|WP_071921501.1\|4527743_4528346_-\|DUF2857-domain-containing-protein	unknown	unknown	gnl\|CDD\|378591
NZ_CP015113.1\|WP_071921489.1\|4519345_4519555_+\|DUF2767-family-protein	unknown	unknown	gnl\|CDD\|182359
NZ_CP015113.1\|WP_071921508.1\|4534937_4535696_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|379263
NZ_CP015113.1\|WP_071921497.1\|4525142_4525862_-\|TIGR03761-family-integrating-conjugative-element-protein	unknown	unknown	gnl\|CDD\|274771
NZ_CP015113.1\|WP_071921503.1\|4529163_4529421_-\|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224648
NZ_CP015113.1\|WP_071921505.1\|4531113_4532478_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NZ_CP015113.1\|WP_071921491.1\|4519993_4520608_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015113.1\|WP_071921500.1\|4527513_4527744_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015113.1\|WP_071921494.1\|4521396_4521903_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|236362
NZ_CP015113.1\|WP_071921493.1\|4521012_4521255_-\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NZ_CP015113.1\|WP_071921502.1\|4528430_4529174_-\|DUF2786-domain-containing-protein	unknown	unknown	gnl\|CDD\|378525
NZ_CP015113.1\|WP_071921492.1\|4520780_4521029_-\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424
NZ_CP015113.1\|WP_007370175.1\|4536192_4537779_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP015113.1\|WP_071921506.1\|4532477_4533392_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NZ_CP015113.1\|WP_071921504.1\|4529413_4531117_-\|ParB-family-protein	unknown	unknown	gnl\|CDD\|213858
NZ_CP015113.1\|WP_071921490.1\|4519642_4519918_-\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424

Protein	Function_ID	Function_description	E-value
NZ_CP015113.1\|WP_071921507.1\|4533912_4534836_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176166	cd08477, PBP2_CrgA_like_8, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 8. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.01516e-91
NZ_CP015113.1\|WP_071921495.1\|4521979_4522474_-\|DUF3577-domain-containing-protein	gnl\|CDD\|371899	pfam12101, DUF3577, Protein of unknown function (DUF3577). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 143 to 307 amino acids in length.	2.75195e-60
NZ_CP015113.1\|WP_071921488.1\|4517854_4519147_-\|TcpQ-domain-containing-protein	gnl\|CDD\|163460	TIGR03748, conj_PilL, conjugative transfer region protein, TIGR03748 family. This model describes the conserved N-terminal region of a variable length protein family associated with laterally transfered regions flanked by markers of conjugative plasmid integration and/or transposition. Most members of the family have the lipoprotein signal peptide motif. A member of the family from a pathogenicity island in Salmonella enterica serovar Dublin strain was designated PilL for nomenclature consistency with a neighboring gene for the pilin structural protein PilS. However, the species distribution of this protein family tracks much better with markers of conjugal transfer than with markers of PilS-like pilin structure. [Mobile and extrachromosomal element functions, Plasmid functions].	2.1199e-53
NZ_CP015113.1\|WP_071921496.1\|4523112_4525125_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP015113.1\|WP_071921489.1\|4519345_4519555_+\|DUF2767-family-protein	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	1.21341e-17
NZ_CP015113.1\|WP_071921508.1\|4534937_4535696_+\|SDR-family-oxidoreductase	gnl\|CDD\|379263	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase.	5.562e-69
NZ_CP015113.1\|WP_071921497.1\|4525142_4525862_-\|TIGR03761-family-integrating-conjugative-element-protein	gnl\|CDD\|274771	TIGR03761, ICE_PFL4669, integrating conjugative element protein, PFL_4669 family. Members of this protein family, such as PFL4669, are found in integrating conjugative elements (ICE) of the PFGI-1 class as in Pseudomonas fluorescens.	4.04794e-83
NZ_CP015113.1\|WP_071921503.1\|4529163_4529421_-\|TraR/DksA-family-transcriptional-regulator	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.10889e-11
NZ_CP015113.1\|WP_071921505.1\|4531113_4532478_-\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP015113.1\|WP_071921501.1\|4527743_4528346_-\|DUF2857-domain-containing-protein	gnl\|CDD\|378591	pfam11198, DUF2857, Protein of unknown function (DUF2857). This is a bacterial family of uncharacterized proteins.	1.90472e-65
NZ_CP015113.1\|WP_071921494.1\|4521396_4521903_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|236362	PRK09010, PRK09010, single-stranded DNA-binding protein; Provisional.	7.04328e-94
NZ_CP015113.1\|WP_071921493.1\|4521012_4521255_-\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	4.86441e-16
NZ_CP015113.1\|WP_071921502.1\|4528430_4529174_-\|DUF2786-domain-containing-protein	gnl\|CDD\|378525	pfam10979, DUF2786, Protein of unknown function (DUF2786). This family of proteins has no known function.	1.31518e-09
NZ_CP015113.1\|WP_071921492.1\|4520780_4521029_-\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	6.85996e-20
NZ_CP015113.1\|WP_007370175.1\|4536192_4537779_-\|HAMP-domain-containing-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	1.3438e-123
NZ_CP015113.1\|WP_071921506.1\|4532477_4533392_-\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	3.76043e-20
NZ_CP015113.1\|WP_071921504.1\|4529413_4531117_-\|ParB-family-protein	gnl\|CDD\|213858	TIGR03764, ICE_PFGI_1_parB, integrating conjugative element, PFGI_1 class, ParB family protein. Members of this protein family carry the ParB-type nuclease domain and are found in integrating conjugative elements (ICE) in the same class as PFGI-1 of Pseudomonas fluorescens Pf-5.	1.51031e-149
NZ_CP015113.1\|WP_071921490.1\|4519642_4519918_-\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	3.14232e-07

>NZ_CP015113.1|WP_071921497.1|4525142_4525862_-|TIGR03761-family-integrating-conjugative-element-protein
MAEKQKRAGALQSELHIELHTNYAIGLWEGRKAEKREDGKKGKQPIMGMPQFLYRATLINKDSLQNDPWADMTMLALEEKINLAGKEMNMLIETLDKQMSFVPAGVTISDAHASEPLDLTVFSGTPLGYRCVFLLMGFDQFAKKVLQAAHYGVISRTQRYELLGNGSRLLREIYGCVLQYRKTGATRLDAVENNEVWQKACQEAGEPDRAVLLGEKRSAFSPPVNEASVNLLRLRYQAI
>NZ_CP015113.1|WP_071921496.1|4523112_4525125_-|DNA-topoisomerase-III
MRLFICEKPSQGRDLAGVLGATRRGDGFLAGSGVTVTWAVGHLLETAPPEAYGQQYGKPWSLSALPILPAPWQVVVKKETQDQFKVIERLLRQVDDVVIATDADREGEVIARELLDYCRWEGPVQRLWLSALDELSIRAALQDLRPGQATLGMYHAGLGRARADWLIGMNLSRLYTLRAAEAGFDGVVSVGRVQTPTLALVVRRDREIAAFVPKPFWQVNALISAGGLTFPAQWVPAKVYTDEEKRCIHQNIAQQVAQLCRQSGHAVVTECDTKREKDAAPLAFSLGSLQQACGRLWDMSPQQVLDTAQSLYEKHKATTYPRTDCGYLPESMREEISGVLDAISRTDPECAPVLARLDRAFVSRIWNDKKITAHHGIIPTRNAFQLSALTETERNVYMLIRRNYLAQFLPLHESDITRLQFDIGGQLFRATGRTEVIKGWKVLFEKAGDDEVQDDDGAGVALPPLAKNDRVTVTGAEVIQQMTRPPAHYTFATLIGAMMNAAAFVTDVALRKVLKDNAGLGTEATRAGIVEQLLNRHFIVRKGSKIMATELGADVIDALPPQLTEPGMTALWEQALDEVAAGRMSLDDFLQRQTGWTRNLVSQGTQQQVRIRVSPTPACPLCGGKTRLRRGEKGEFWSCQRWPECKGVINIGGIRKKRPRRAKSPESKKN
>NZ_CP015113.1|WP_071921495.1|4521979_4522474_-|DUF3577-domain-containing-protein
MTATASTPASSSASASSQQKKEYFNLNVNGIGYLSSIRRVQSGNGEFTCAVINALTGPTDNASYQRFDVTVAGTDTTKLINRCLKAVDEEEKVLIGFVLSGLKAEVFTLQSGDHAGESRPSLKARLIKVEFIKKGQDVVYQAPNASQMPESGSSAQKEYDPNSF
>NZ_CP015113.1|WP_071921494.1|4521396_4521903_-|single-stranded-DNA-binding-protein
MSARGVNKVILVGHLGQDPEVRYLPNGNAVAGLSLATSESWRDKQTGEMKENTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRKWTDNSGTDRWTAEIVVGVNGTMQMLGGGRNNSTNTSGNGNNAQSGQQGGWGQPQQPQQAQSAPRNPGNEPPMDFDDDIPF
>NZ_CP015113.1|WP_071921493.1|4521012_4521255_-|DUF4160-domain-containing-protein
MPVILRLNGFKFFFYSNEGNPLEPAHIHVRNADGEAKFWLEDAVTLSRNDGFDARTLRALTKMVEDNQRFFVEAWNEYFS
>NZ_CP015113.1|WP_071921492.1|4520780_4521029_-|DUF2442-domain-containing-protein
MSISAKNVKFDETTMWVELSDERVLGVPLAWFPRLLNASAQQLNDYELSKRGIHWDELDEDISVEGLLAGRGDISHLPGRVA
>NZ_CP015113.1|WP_071921491.1|4519993_4520608_-|hypothetical-protein
MKFMKHFPLIFLVPALLMAGCSQRAQQAPTQVTLLNSASEIPQGTISLSTTLIHVKKKHAIAWKDVLPEWNPAKMVFIFQGDAPAVHDRIAARSDVSIEYASTGTTNNGDPMPISVHRNSDTNDGGTLVNKGLDLTLIPWYQNVNGPINLRFSLNIQDERGSFQASQLMSLQQGKSLLISRIIDENTQEVLIVTPRIDPQGLPG
>NZ_CP015113.1|WP_071921490.1|4519642_4519918_-|DUF2442-domain-containing-protein
MNVSIKQVRIADAMLWVELNDSRVLGTPLTRFPRLLQAGEHERQQFEIFRDGVRWKASGEEIFLTDLFSLSLASDDTNVSEVQAGAASAGR
>NZ_CP015113.1|WP_071921489.1|4519345_4519555_+|DUF2767-family-protein
MEPQITADELYDEMCRVIGDMVMIFHDFNIEPKHIVIADALRTAMISDSGERSKMTLKAMELAIKTLET
>NZ_CP015113.1|WP_071921488.1|4517854_4519147_-|TcpQ-domain-containing-protein
MVKLQKRAGEHYRLAGVALCLIAAGCADSSRTEPLSRLQGAPRVQDVYQNTSPEVVRYDRYTLASTRPADAQRDPLNQIIEIRMPQQVVRTVGEGLRYLLLESGYSLCNGDATVFAELFSKPLPAVQRSVGPVRLTEALQVLAGPAWRLHVDDVNREVCFALRDQYRHFAPTASVSVPGSSLSQGAAPNSGSLLSPGLKPAATGNNSFPLPPARPEGPGAPGTISSVTQAASSGTPKVPRNPFSAGASAGPSPTPAQKTQAGIVSQSASGKIKPSTALAPAPAVLSVPVTPLNTAALGVAPVSAPKADRTVQGKNLSSATPPAFIPGAPLSSLPDGQVWTAKAGTTLKETLTQWASSVHCESGSSPTWVVIWPTPVNYRIEAPFTLRGNFESMIVQLFDLYRKAEKPLYAGPNRLQCLVYVDDKPIQDGQ
>NZ_CP015113.1|WP_071921500.1|4527513_4527744_-|hypothetical-protein
MEMVDFSLRQQVSPSVRRRAQRLFRAACCGQKVFRRLTMNGYLKIDVGPFWRILSKDGGRQWWLMDHETYNREIRR
>NZ_CP015113.1|WP_071921501.1|4527743_4528346_-|DUF2857-domain-containing-protein
MSQHNLSLSQATTAILSSLLMDVKNGNIRRCESLGMSVEEIRELSRLSLDELHYLSQSHVSVLDVTLNHENFWLMLNQARNEQKRFMMIDRALELGGSMELIDRYFGLSPSEVSARRRLMGIESRQGRTQSLTEPQDAALWAEWKAAGLSSPDSHQALEAMMLAAELHGLSLTAVWSRVCQWCREATPSRAPDSRQRKEA
>NZ_CP015113.1|WP_071921502.1|4528430_4529174_-|DUF2786-domain-containing-protein
MQDNAKVTARIRRLMALGTRNSNPHEAARAVALAQRLMQRHGLTPDMLSLSDITESVCLSLTSDADKVPAWMSSLATVVCMATGCRCWFSWHVHVSTHGVNSMRRSLHFYGFRERPEVALYIYTVLQRQLRAATDVHMAGYRNRRILLRTRRRRADQFREGWVSGVWQVLQSFSPSEGENVALQRWLARRHAGEQLEGMTVRSAGKCRGDRTARMAGFLASRDAELHHGLSGAQAPRQIATGGGTHD
>NZ_CP015113.1|WP_071921503.1|4529163_4529421_-|TraR/DksA-family-transcriptional-regulator
MSDDLNDEMAQASTALFIQHGIDAIRAKVNSATPSKAFCECCGAAIPVARQLAVPGVDLCAGCQEVKEMKNRHRADGVRGKRHAG
>NZ_CP015113.1|WP_071921504.1|4529413_4531117_-|ParB-family-protein
MNNVRNLNLGAAMLQRGKSPSLTAETPAAPLPVSEMAMVLTLDQLRPNPDNPRKGRNPRYDEIKASVRARGLDSIPKVTRDPDGDDVYIFSDGGNTRYQILCELWQETGDERFYRVHTIFKPWPGRLKCLVGHLAENEVRGDLAYIEKAFGVHKARVIYEEQLGRAVTLRELSDLLGQEGYPIDNSSVSRMEDTLNYLYPHMPNLLEGGMSRGQVTPLLSLRSSAMKVWKSFSGDVKPDCTLDDVFGATCRCFDMPDSYALDVFRDEFIGQLVKALPHPSLNYDRWLIELDPREQKRREQFGDPPPLPAMTPPPERVAGRESPEAPVTVLSPDTASETPVTGLRSGTLTTRGRPEPAQELPAGAGLPVNERVTAGSEPRREVQNDLFGGRPVISGETADTDSISLPDLNPGTLMSAFGEENASPAASVSSIAFAATGLEPVSDIWHIPALQDDIEHLQDMAYRLVFEIAEAMGCADNVREDKHPQSAGFAVSETGSEFVLFLAGLSGSLPSRQFNMFMFCLNFFGSQSPADVAVFDDITVVKTMRLVRVIRRLRELQRLAAKGGENV
>NZ_CP015113.1|WP_071921505.1|4531113_4532478_-|replicative-DNA-helicase
MSQQKQNLTGLFSRDAEQSVLGGLMLDNDCWDEVALLVSTDDFYYHVHRTIFREMTHLISAGKPIDLITLTDSIESQGTNAIEQLGGFAYLAELSKNTPSAANIRAYCEIVAKFSQARQLARIGADITESVQKPGADIPAVMEDAEQKITRLAERGEPEQGVTLLEGMERLLPELERRCNVPDGITGTPTGFGELDSMTSGLQAGDLVLIAARPSMGKTAFLINLLLNSLMKKSGSKGQLYSMEQPTEQILMRMLASLGSIDLTHLKSGLMDDEDWARATDASAMLMGDLNDSLIIDDTGSLTPAMLRIRARRNARRYGHPSIIGLDYLQLMRCPDQENRTQEIAEISRSLKALAKEMMCPVVALSQLNRQLESRADKRPNNGDLRDSGALEQDADVIVFIYRDEVYHENTEDKGVAEIIISKQRQGPTGTVRLQYEGRYTRFSDITGRSRGNA
>NZ_CP015113.1|WP_071921506.1|4532477_4533392_-|ParA-family-protein
MHLKSEAYRSVGLSPKILPVVSTKGGEGKSTQSANLAGFLADAGIKTLLLDGDHAQPTASSIFPLEYEAPCGLYELLMQTADLSDPDNLISRTSIENLDVIVSNDPRNFLPTAMLNAADGRVRLRNALSHPLFNKYGVIIVDSQGSRSVMSELIILASSGTMVGIAKPKLADVREFMRGTVALMEELLPYGNFGIQLPETKLLINCMDYDNLSVESLAQVKKIVEEKRYSTHADKIHIELLETYIYDLTVYVMGHVKGVPVHRLEKNTSRKSDSAFSSMYQLACELFPEWKENFDALAKAGEVE
>NZ_CP015113.1|WP_071921507.1|4533912_4534836_-|LysR-family-transcriptional-regulator
MDLFRAMTVFAEVARSGSMSAASRKLLITPVMVGQYVAALEDRLGMRLLNRTTRKQKLTDFGLSYLEQCHDILERVAASETQAEGLQHSFGGKLRLTAPISFGTECLIPALQRYRKMAPDVEIDITLTDRVIDLVDEGIDIAFRIGELNDSSMIGRPLMPYRMAVCASPEYLQAYGTPAHPSELFEHQLLSLSTSSRSPWRLSRGEEKIEIPVHSKLTINNGQALRVAARSGLGIVMQPEILLSEDMISGRLVRLFQEWHIRERQVWLLYLRDKRMTPKIRAFINFSLEAFSAGKVEANPHNQPLTP
>NZ_CP015113.1|WP_071921508.1|4534937_4535696_+|SDR-family-oxidoreductase
MNRLRFVDKTVVVTGAGSGMGRTAAIRLASEGAKVMLLGRQAGMLEEVRDEIKRADGLSYVFPCDIRSQSQVEKTFTAVASVCGQVDALFANAGYLGAFKPLAEADIADFSEPLETNLNGTFLTIRHCLPLIKKGAILINASWTTGSVMPGAGIYAATKAALLAIMRTLAVECGPRGIRVNAVSPGVILTPMAASALPEATVNALASRSLLQRNGVPEDISGTVAWLLSDDASYVTGQEIMVDGGFTIGGMR
>NZ_CP015113.1|WP_007370175.1|4536192_4537779_-|HAMP-domain-containing-protein
MKNISVRVALSGAISIFVLIIVAISSVGFFAFTRSTNTTEFIHNSDSRVILINDIYKDSARTRAGFALVYASLLKEGKTEAWVFKNIQTTHERMLVNLRRFETLPVMDSRDEEIKTELVTSAGALNTLLDKAEQLLKAGDVQGYYDVNVQQIDKAGGRFSAALEKYQKSTNEIVNNLVDEQQKQYRQLLWVMFVGLLLALLISVAVLYVLRNVILRPLNYAIEHLDTVAKGDLTTNIQMAGNNEIGKLLNAIRGMQESLRNLVAQVRNGVDEIHVGSREIAAGNLDLSSRTEEQASSLEETAASMEQLASIVKQNADNAYQANLLALKASEIAESGGKAVSEVVQTMDEIATSSSKIADIVSMIDSISFQTNILALNAAVEAARAGEQGKGFAVVASEVRTLAQRSASAAKEIKDLIQNSTDRVNAGTEQVGRAGAAMLEIVTSVKHVTDTVAEISHASREQASGIDQVNLAVSQMDGVTQQNASLVEQAAAAANSLELQASALAEAISTFRVNHDTTSRSSGRLTVA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015113_1	1.1\|2234724\|40\|NZ_CP015113\|CRISPRCasFinder	2234724-2234763	40	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	18821-18860	11	0.725

1. spacer 1.1|2234724|40|NZ_CP015113|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 11, identity: 0.725

tgccggtttagctgcttttttgtgatgttttttcactttt	CRISPR spacer
ttcgtgttttgctgcttttttgtgatgctttttagccgcc	Protospacer
* *  **** *****************.***** .*. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1074136 : 1137375

Enterobacteria_phage(31.82%)

head,plate,tRNA,portal,capsid,terminase,protease,tail,integrase

attL 1086805:1086824|attR 1145348:1145367

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007373603.1\|1074136_1074616_-\|tRNA	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK	NA	NA	NA	NA
WP_007373604.1\|1074695_1075505_-	TraB/GumN family protein	NA	NA	NA	NA
WP_007373605.1\|1075594_1078093_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	1.5e-111	37.7
WP_172825167.1\|1078394_1079324_+	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_071920345.1\|1079389_1079638_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_071920346.1\|1079686_1080838_-	phage late control D family protein	B9A7A9	Serratia_phage	3.1e-173	78.3
WP_071920347.1\|1080988_1082170_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A7NV69	Enterobacteria_phage	2.8e-153	67.8
WP_071920348.1\|1082170_1082686_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	1.2e-52	60.4
WP_071920349.1\|1082742_1083042_+\|tail	phage tail assembly protein	B9A7B2	Serratia_phage	2.2e-33	75.8
WP_156897435.1\|1083038_1083209_+\|tail	GpE family phage tail protein	O80316	Escherichia_phage	7.9e-09	59.1
WP_074989280.1\|1083189_1086153_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	1.7e-191	41.9
WP_071920352.1\|1086164_1086653_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	1.1e-53	61.7
1086805:1086824	attL	NA	NA	NA	NA
WP_071920353.1\|1086944_1087652_-	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_071920354.1\|1088021_1088411_+	hypothetical protein	NA	NA	NA	NA
WP_071920355.1\|1088565_1088886_-	DUF1493 family protein	NA	NA	NA	NA
WP_071920356.1\|1088879_1089338_-	hypothetical protein	A0A218M4J4	Erwinia_phage	6.7e-10	34.9
WP_156897408.1\|1089502_1089925_-\|tail	tail fiber assembly protein	A0A0F7LDZ0	Escherichia_phage	9.2e-30	48.2
WP_071920358.1\|1089921_1091187_-\|tail	phage tail protein	A0A0F7LBW5	Escherichia_phage	1.4e-102	53.7
WP_071920359.1\|1091183_1091792_-\|tail	phage tail protein I	A0A218M4J3	Erwinia_phage	1.5e-70	64.4
WP_071920360.1\|1091784_1092681_-\|plate	baseplate J/gp47 family protein	A0A0A7NPY5	Enterobacteria_phage	7.8e-103	67.1
WP_071920361.1\|1092667_1093036_-	GPW/gp25 family protein	A0A0A7NQ90	Enterobacteria_phage	2.0e-33	62.6
WP_071920362.1\|1093032_1093617_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	5.6e-62	61.5
WP_071920363.1\|1093616_1094258_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	6.2e-46	50.0
WP_071920364.1\|1094254_1094716_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	2.5e-33	48.7
WP_071920365.1\|1094712_1095276_-	hypothetical protein	K7PHH7	Enterobacteria_phage	5.0e-39	53.9
WP_172825185.1\|1095272_1095752_-	glycoside hydrolase family protein	A0A1R3Y5W5	Salmonella_virus	1.0e-48	57.0
WP_071920367.1\|1095757_1096060_-	hypothetical protein	O64361	Escherichia_phage	4.1e-32	68.3
WP_071920368.1\|1096111_1096312_-\|tail	tail protein X	A0A0M4RTN6	Salmonella_phage	1.0e-15	66.2
WP_071920369.1\|1096311_1096809_-\|head	head completion/stabilization protein	B9A7B7	Serratia_phage	1.5e-60	70.3
WP_071920370.1\|1096911_1097820_-\|terminase	terminase	B9A7B6	Serratia_phage	2.7e-87	73.6
WP_071920371.1\|1097868_1098918_-\|capsid	phage major capsid protein, P2 family	A0A0M3ULA3	Salmonella_phage	2.7e-107	55.4
WP_071920372.1\|1098941_1099775_-\|capsid	GPO family capsid scaffolding protein	B9A7B4	Serratia_phage	2.3e-101	66.8
WP_071920373.1\|1099934_1101656_+	helix-turn-helix domain-containing protein	A0A0A7NV54	Enterobacteria_phage	1.3e-226	66.2
WP_071920374.1\|1101658_1102711_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	8.1e-144	69.7
WP_071920375.1\|1103286_1103865_+	sce7726 family protein	A0A0U2RXY7	Escherichia_phage	8.0e-77	74.0
WP_071920376.1\|1103824_1104922_-	beta family protein	A0A0U2S621	Escherichia_phage	4.0e-133	63.3
WP_083565967.1\|1105041_1107495_-	replication endonuclease	F1BUS0	Erwinia_phage	3.4e-140	41.7
WP_071921833.1\|1107526_1108390_-	DNA adenine methylase	E5G6L8	Salmonella_phage	8.3e-102	64.6
WP_071920377.1\|1108396_1108615_-	TraR/DksA family transcriptional regulator	A0A0M4S5Q7	Salmonella_phage	1.2e-17	62.5
WP_071920378.1\|1108614_1108854_-	DUF2732 family protein	A0A1S6L021	Salmonella_phage	1.2e-10	52.0
WP_071920379.1\|1108857_1109064_-	hypothetical protein	A0A0M4R514	Salmonella_phage	1.5e-14	57.4
WP_071920380.1\|1109147_1109378_-	DUF2724 domain-containing protein	A0A0M4S6M9	Salmonella_phage	1.8e-32	82.9
WP_071920381.1\|1109367_1109571_-	DUF4761 family protein	A0A0M5M1I3	Salmonella_phage	3.0e-23	76.9
WP_071921834.1\|1109603_1109939_-	hypothetical protein	NA	NA	NA	NA
WP_071920382.1\|1110190_1110490_+	helix-turn-helix transcriptional regulator	Q1JS29	Enterobacteria_phage	9.0e-32	65.7
WP_071920383.1\|1110559_1111582_+\|integrase	tyrosine-type recombinase/integrase	Q83VS6	Escherichia_phage	4.9e-93	52.0
WP_007373606.1\|1111747_1112044_-	NINE protein	M4ZS56	Bacillus_phage	1.8e-16	65.6
WP_007373607.1\|1112215_1112623_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_007373608.1\|1112626_1113085_-	NfeD family protein	NA	NA	NA	NA
WP_035887325.1\|1113081_1113999_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_007373610.1\|1114085_1114940_-	co-chaperone YbbN	NA	NA	NA	NA
WP_007373611.1\|1115001_1115772_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_007373612.1\|1115801_1116425_-\|protease	multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1	NA	NA	NA	NA
WP_071920384.1\|1116395_1117082_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.8e-06	27.7
WP_071920385.1\|1117078_1119493_+	ABC transporter permease	NA	NA	NA	NA
WP_007373615.1\|1119689_1120841_+	porin	NA	NA	NA	NA
WP_035887327.1\|1121142_1121979_+	methionine ABC transporter ATPase	NA	NA	NA	NA
WP_007373617.1\|1122036_1123059_+	virulence-associated ABC transporter ATP-binding protein SfbB	A0A1V0SGN0	Hokovirus	5.7e-09	28.1
WP_007373618.1\|1123051_1123711_+	ABC transporter permease	NA	NA	NA	NA
WP_071920386.1\|1123782_1124868_-\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
WP_156897409.1\|1125206_1125728_+	hypothetical protein	NA	NA	NA	NA
WP_071920387.1\|1125852_1126920_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_007373622.1\|1126916_1127426_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_071920388.1\|1127555_1128278_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_007373624.1\|1128280_1128775_-	peptidylprolyl isomerase B	NA	NA	NA	NA
WP_074989282.1\|1128948_1130334_+\|tRNA	cysteine--tRNA ligase	A0A2K9L6B7	Tupanvirus	1.8e-42	33.2
WP_071920390.1\|1130467_1130989_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_071920391.1\|1131218_1132235_-	Mal regulon transcriptional regulator MalI	NA	NA	NA	NA
WP_071920392.1\|1132316_1133816_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_007373629.1\|1134102_1134315_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_007373630.1\|1134316_1135183_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	3.8e-30	36.2
WP_071920393.1\|1136169_1137375_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.4e-131	56.5
1145348:1145367	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1259128 : 1267260

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007373714.1\|1259128_1259461_+	helix-turn-helix domain-containing protein	D0R0F8	Streptococcus_phage	6.1e-05	29.5
WP_007373715.1\|1259623_1260316_+	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	5.5e-32	34.2
WP_007373716.1\|1260327_1261734_+	heavy metal sensor histidine kinase	NA	NA	NA	NA
WP_007373717.1\|1261908_1262229_+	metalloregulator ArsR/SmtB family transcription factor	A0A2H4J145	uncultured_Caudovirales_phage	7.7e-21	48.0
WP_007373718.1\|1262272_1263562_+	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	2.0e-168	72.3
WP_007373719.1\|1263574_1264000_+	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	1.9e-51	70.7
WP_007373720.1\|1264086_1264341_-	DUF1471 domain-containing protein	A0A1B2ICL8	Erwinia_phage	9.4e-06	49.1
WP_007373721.1\|1264551_1265679_-	porin OmpC	Q1MVN1	Enterobacteria_phage	8.5e-99	51.3
WP_071920439.1\|1265843_1266302_-	hypothetical protein	NA	NA	NA	NA
WP_007373724.1\|1266545_1266902_-	helix-turn-helix domain-containing protein	D0R0F8	Streptococcus_phage	3.2e-07	36.9
WP_007373725.1\|1267005_1267260_-	DUF1471 domain-containing protein	A0A1B2IB27	Erwinia_phage	6.1e-05	49.1

DBSCAN-SWA_3

2844911 : 2924083

Tupanvirus(20.0%)

protease,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071920929.1\|2844911_2846711_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_035888589.1\|2846701_2847643_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_035888591.1\|2847657_2849796_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_007371753.1\|2849806_2850253_+	hypothetical protein	NA	NA	NA	NA
WP_035888596.1\|2850252_2850552_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_071920930.1\|2850558_2851611_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_035888602.1\|2851610_2852240_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_007371749.1\|2852241_2853603_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_035888605.1\|2853599_2854220_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_071920931.1\|2854226_2857655_+	hypothetical protein	NA	NA	NA	NA
WP_071920932.1\|2857674_2860185_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	2.3e-83	34.1
WP_007371745.1\|2860706_2861261_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_007371744.1\|2861803_2862592_+	hypothetical protein	NA	NA	NA	NA
WP_007371743.1\|2862913_2865097_+	catalase/peroxidase HPI	NA	NA	NA	NA
WP_007371742.1\|2865442_2865652_-	hypothetical protein	NA	NA	NA	NA
WP_007371741.1\|2865829_2866810_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_007371739.1\|2866888_2867899_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_007371738.1\|2867943_2868297_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_071920933.1\|2868380_2869265_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_035888619.1\|2869306_2870338_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	1.8e-34	28.1
WP_007371735.1\|2870365_2871886_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_071920934.1\|2872159_2873896_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_158262945.1\|2873927_2874731_-\|protease	serine protease	NA	NA	NA	NA
WP_083566005.1\|2875227_2876832_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_071920935.1\|2877012_2877624_-	hypothetical protein	NA	NA	NA	NA
WP_035888621.1\|2877636_2878131_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_035888623.1\|2878127_2878550_-	hypothetical protein	NA	NA	NA	NA
WP_007371728.1\|2878593_2879982_-	Fe-only nitrogenase subunit beta	NA	NA	NA	NA
WP_007371727.1\|2879993_2880338_-	Fe-only nitrogenase subunit delta	NA	NA	NA	NA
WP_007371726.1\|2880334_2881906_-	nitrogenase iron-iron protein, alpha chain	NA	NA	NA	NA
WP_035888626.1\|2881950_2882778_-	nitrogenase iron protein	NA	NA	NA	NA
WP_007371723.1\|2883005_2883704_-	glutamine amidotransferase	A0A2K9L2L9	Tupanvirus	7.3e-08	26.7
WP_071920936.1\|2884114_2885464_+	MFS transporter	NA	NA	NA	NA
WP_071920937.1\|2885504_2887157_-	malate dehydrogenase (quinone)	NA	NA	NA	NA
WP_035887378.1\|2887438_2888353_-	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
WP_035887380.1\|2888529_2890146_+	two-component system sensor histidine kinase DcuS	NA	NA	NA	NA
WP_007371716.1\|2890142_2890862_+	two-component system response regulator DcuR	NA	NA	NA	NA
WP_071920938.1\|2890842_2891805_-	FAD:protein FMN transferase	NA	NA	NA	NA
WP_071920939.1\|2891969_2894747_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	8.4e-71	32.1
WP_071920940.1\|2895384_2896896_+	anion permease	NA	NA	NA	NA
WP_035887388.1\|2896947_2898597_+	fumarate hydratase	NA	NA	NA	NA
WP_071920941.1\|2898894_2899152_-	hypothetical protein	NA	NA	NA	NA
WP_071920942.1\|2899497_2899800_-	hypothetical protein	NA	NA	NA	NA
WP_007371709.1\|2899999_2900410_-	RHS domain-containing protein	A0A2H4JFP5	uncultured_Caudovirales_phage	8.4e-20	46.8
WP_079517793.1\|2900464_2900803_-	hypothetical protein	NA	NA	NA	NA
WP_071920943.1\|2900812_2905240_-	PAAR/RHS domain-containing protein	A0A2H4JFP5	uncultured_Caudovirales_phage	7.4e-29	48.3
WP_071920944.1\|2905253_2905682_-	DcrB-related protein	NA	NA	NA	NA
WP_107146662.1\|2905792_2906230_-	hypothetical protein	NA	NA	NA	NA
WP_071920945.1\|2906303_2908883_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	6.6e-46	28.7
WP_007371701.1\|2908977_2909370_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_007371700.1\|2909379_2909985_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_071920946.1\|2909981_2911067_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_071920947.1\|2911063_2913604_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_071920948.1\|2913827_2914214_-	DUF3592 domain-containing protein	NA	NA	NA	NA
WP_071920949.1\|2914228_2916463_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	6.3e-45	28.3
WP_007371692.1\|2916521_2916962_-	DcrB-related protein	NA	NA	NA	NA
WP_007371691.1\|2917051_2918488_-	protein kinase	M1HXR9	Acanthocystis_turfacea_Chlorella_virus	3.6e-09	27.3
WP_071920950.1\|2918514_2921127_-	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	8.4e-81	31.1
WP_007371689.1\|2921171_2922215_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_007371688.1\|2922211_2924083_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_4

3261412 : 3271959

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007371280.1\|3261412_3262726_-	lipopolysaccharide biosynthesis protein RfbH	H8ZJ36	Ostreococcus_tauri_virus	2.8e-53	35.4
WP_071921051.1\|3262747_3263827_-	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	3.1e-13	23.5
WP_007371278.1\|3263830_3264604_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_007371277.1\|3264620_3265595_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_007371276.1\|3265601_3266150_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	3.2e-51	56.2
WP_007371275.1\|3266152_3267031_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.5e-106	64.1
WP_071921052.1\|3267079_3267979_-	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	7.0e-27	33.2
WP_071921053.1\|3267981_3269064_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.0e-101	54.2
WP_007371272.1\|3269463_3270357_-	GalU regulator GalF	A0A127AW70	Bacillus_phage	1.3e-44	41.2
WP_071921054.1\|3270543_3271959_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	2.4e-18	32.1

DBSCAN-SWA_5

3354068 : 3362452

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007371208.1\|3354068_3356102_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.5e-53	27.6
WP_007371207.1\|3356171_3356627_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	9.9e-30	44.9
WP_007371206.1\|3356754_3357231_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.9e-63	78.8
WP_007371205.1\|3357283_3358003_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_007371204.1\|3357996_3359685_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	3.2e-259	84.7
WP_071921073.1\|3359905_3360637_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	1.6e-82	73.9
WP_007371202.1\|3360695_3360809_+	protein YohO	NA	NA	NA	NA
WP_007371201.1\|3360783_3361521_-	ABC transporter permease	NA	NA	NA	NA
WP_007371200.1\|3361504_3362452_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	8.1e-10	26.6

DBSCAN-SWA_6

3795182 : 3874109

Escherichia_phage(23.81%)

plate,tRNA,integrase,tail,holin

attL 3833920:3833934|attR 3875828:3875842

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007370784.1\|3795182_3795701_-\|tRNA	tRNA adenosine(34) deaminase TadA	S4VYT2	Pandoravirus	7.3e-05	42.2
WP_035888209.1\|3795759_3796395_-	phosphatidylglycerophosphatase C	NA	NA	NA	NA
WP_007370782.1\|3796680_3797529_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_007370781.1\|3797585_3797846_+	YfhL family 4Fe-4S dicluster ferredoxin	A0A1B1IWY9	uncultured_Mediterranean_phage	1.1e-17	52.3
WP_007370780.1\|3797842_3798223_-	holo-ACP synthase	NA	NA	NA	NA
WP_071921195.1\|3798222_3798954_-	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_007370778.1\|3799019_3799727_-	DNA repair protein RecO	NA	NA	NA	NA
WP_007370777.1\|3799834_3800746_-	GTPase Era	NA	NA	NA	NA
WP_007370776.1\|3800742_3801423_-	ribonuclease III	E5EQH1	Micromonas_sp._RCC1109_virus	1.3e-20	33.5
WP_007370775.1\|3801634_3802609_-	signal peptidase I	NA	NA	NA	NA
WP_035888216.1\|3802624_3804424_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	7.2e-23	25.2
WP_071921196.1\|3804569_3805049_-	SoxR-reducing system protein RseC	NA	NA	NA	NA
WP_071921197.1\|3805045_3805999_-	sigma-E factor regulatory protein RseB	NA	NA	NA	NA
WP_071921198.1\|3805998_3806652_-	anti-sigma-E factor RseA	NA	NA	NA	NA
WP_007370770.1\|3806683_3807259_-	RNA polymerase sigma factor RpoE	NA	NA	NA	NA
WP_007370769.1\|3807679_3809302_+	L-aspartate oxidase	NA	NA	NA	NA
WP_007370768.1\|3809286_3810024_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_007370767.1\|3810153_3811482_+	ATP-dependent RNA helicase SrmB	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.3e-42	30.4
WP_007370766.1\|3811525_3811909_-	autonomous glycyl radical cofactor GrcA	A0A193GZ98	Escherichia_phage	3.1e-32	71.8
WP_007370765.1\|3812221_3812911_+	uracil-DNA glycosylase	A0A077BCN4	Equid_alphaherpesvirus	4.6e-55	51.4
WP_007370764.1\|3812955_3814053_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_007370763.1\|3814259_3814679_+	thioredoxin TrxC	A0A1J0GW78	Streptomyces_phage	2.0e-13	41.5
WP_007370762.1\|3814748_3815447_+	DTW domain-containing protein	NA	NA	NA	NA
WP_071921199.1\|3815479_3818140_+	protein lysine acetyltransferase	NA	NA	NA	NA
WP_007370760.1\|3818253_3819609_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_035888232.1\|3819654_3819978_+	YfiM family lipoprotein	NA	NA	NA	NA
WP_035888236.1\|3819974_3821273_-	MFS transporter	Q6JIH2	Burkholderia_virus	5.3e-44	31.8
WP_071921201.1\|3826984_3829558_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	1.1e-125	34.6
WP_035888442.1\|3829687_3830419_-	polyphenol oxidase	NA	NA	NA	NA
WP_007370752.1\|3830415_3831396_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_007370751.1\|3831527_3832265_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_007370750.1\|3832530_3832869_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_071921202.1\|3833116_3834277_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
3833920:3833934	attL	NA	NA	NA	NA
WP_007370748.1\|3834273_3835146_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_007370747.1\|3835212_3836334_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_007370746.1\|3836343_3837414_-	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	1.1e-90	51.5
WP_071921203.1\|3837594_3838959_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_071921204.1\|3839021_3839432_-	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_071921205.1\|3839619_3840669_-\|integrase	site-specific integrase	A0A0M4S6G4	Salmonella_phage	1.1e-153	73.9
WP_035888483.1\|3840675_3841524_-	phage repressor protein CI	Q6K1G0	Salmonella_virus	3.7e-94	62.4
WP_007370740.1\|3841639_3842017_+	hypothetical protein	A0A0M4R4X7	Salmonella_phage	6.0e-41	69.2
WP_035888424.1\|3842055_3842394_+	DUF5347 domain-containing protein	A0A218M4I7	Erwinia_phage	3.3e-38	68.5
WP_007370738.1\|3842461_3842689_+	DUF2732 family protein	A0A218M4I9	Erwinia_phage	4.2e-05	40.0
WP_007370737.1\|3842688_3842910_+	TraR/DksA family transcriptional regulator	Q6K1F5	Salmonella_virus	6.9e-21	69.0
WP_071921206.1\|3842910_3844884_+	replication endonuclease	A0A218M4H2	Erwinia_phage	1.9e-266	72.5
WP_035888419.1\|3844955_3845141_+	hypothetical protein	A0A0M5M1G5	Salmonella_phage	6.0e-10	55.7
WP_035888416.1\|3845339_3845543_+\|tail	tail protein X	Q858W3	Yersinia_virus	3.5e-19	66.7
WP_064564426.1\|3845533_3845755_+\|holin	holin	A0A218M4L5	Erwinia_phage	5.0e-11	43.8
WP_071921207.1\|3845738_3846248_+	lysozyme	A0A218M4K3	Erwinia_phage	5.1e-67	76.2
WP_071921208.1\|3846244_3846670_+	protein lysB	A0A218M4K2	Erwinia_phage	6.6e-28	54.6
WP_035888407.1\|3846765_3847233_+\|tail	phage tail protein	A0A0F7LA33	Escherichia_phage	1.1e-47	60.1
WP_035888404.1\|3847320_3847956_+\|plate	phage baseplate assembly protein V	A0A0F7LDY9	Escherichia_phage	4.4e-92	80.1
WP_043952630.1\|3847952_3848300_+	GPW/gp25 family protein	A0A0F7LDQ1	Escherichia_phage	7.3e-41	73.0
WP_007370725.1\|3848304_3849213_+\|plate	baseplate assembly protein	A0A218M4K5	Erwinia_phage	5.2e-131	79.8
WP_007370724.1\|3849205_3849814_+\|tail	phage tail protein I	A0A218M4J3	Erwinia_phage	4.5e-86	76.0
WP_071921209.1\|3849968_3850994_+\|tail	phage tail protein	A0A2I8TVA9	Erwinia_phage	3.7e-117	63.2
WP_071921210.1\|3852190_3852787_+\|tail	tail fiber assembly protein	A0A218M4J2	Erwinia_phage	1.1e-60	56.3
WP_071921211.1\|3852992_3854114_+\|tail	phage tail protein	M1TAS6	Escherichia_phage	5.9e-116	48.7
WP_071921212.1\|3854113_3854707_+\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	7.0e-44	50.3
WP_007370717.1\|3854836_3856018_+\|tail	phage tail sheath protein	S4TRX2	Salmonella_phage	1.3e-201	88.3
WP_007370716.1\|3856030_3856549_+\|tail	phage major tail tube protein	Q858V0	Yersinia_virus	4.5e-87	90.1
WP_035888387.1\|3856611_3856893_+\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	9.4e-31	80.7
WP_061493592.1\|3856925_3857045_+\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	7.5e-14	87.2
WP_035888385.1\|3857037_3858750_+\|tail	phage tail tape measure protein	S4TP64	Salmonella_phage	8.3e-29	38.8
WP_035888383.1\|3858746_3859208_+\|tail	phage tail protein	A0A0F7LBX3	Escherichia_phage	7.4e-49	63.4
WP_071921213.1\|3859204_3860347_+	hypothetical protein	Q7Y4C6	Escherichia_virus	1.1e-106	53.1
WP_071531981.1\|3860421_3860613_+	ogr/Delta-like zinc finger family protein	Q37973	Salmonella_virus	1.3e-20	71.9
WP_002914145.1\|3860767_3861115_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_007370710.1\|3861158_3861926_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_071921214.1\|3861956_3862505_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_007370708.1\|3862523_3862772_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_035888381.1\|3863164_3864526_-	signal recognition particle protein	NA	NA	NA	NA
WP_007370706.1\|3864694_3865483_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_035888378.1\|3865501_3866788_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_007370704.1\|3866829_3867426_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_035888376.1\|3867548_3868439_+	NAD(+) kinase	NA	NA	NA	NA
WP_007370701.1\|3868525_3870187_+	DNA repair protein RecN	NA	NA	NA	NA
WP_007370700.1\|3870335_3870677_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_007370699.1\|3870737_3871031_-	RnfH family protein	NA	NA	NA	NA
WP_071921216.1\|3871020_3871497_-	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_007370697.1\|3871616_3872099_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.3e-29	47.4
WP_071921217.1\|3872867_3874109_+\|integrase	integrase	A0A1B5FPC6	Escherichia_phage	1.1e-102	47.5
3875828:3875842	attR	NA	NA	NA	NA

DBSCAN-SWA_7

4373335 : 4436216

Edwardsiella_phage(33.33%)

protease,plate,tRNA,integrase

attL 4411683:4411697|attR 4422728:4422742

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071921397.1\|4373335_4373842_+\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_007370212.1\|4373928_4374627_+	deoxyribonuclease I	NA	NA	NA	NA
WP_007370211.1\|4374719_4375451_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_071921398.1\|4375464_4376412_+	glutathione synthase	NA	NA	NA	NA
WP_007370209.1\|4376530_4377094_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_007370208.1\|4377093_4377510_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_007370207.1\|4377663_4378356_-	hypothetical protein	NA	NA	NA	NA
WP_007370206.1\|4378421_4380680_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_035889571.1\|4380676_4381657_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_007370204.1\|4381674_4382379_+	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_007370203.1\|4382397_4382964_+	YggT family protein	NA	NA	NA	NA
WP_007370202.1\|4382960_4383251_+	YggU family protein	NA	NA	NA	NA
WP_007370201.1\|4383259_4383853_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_007370200.1\|4383845_4384982_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_007370199.1\|4385033_4386137_-	LPS O-antigen length regulator	NA	NA	NA	NA
WP_007370198.1\|4386382_4387102_-	DUF2884 domain-containing protein	NA	NA	NA	NA
WP_007370197.1\|4387157_4387484_-	YggL family protein	NA	NA	NA	NA
WP_007370196.1\|4387483_4388203_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_007370194.1\|4388345_4389395_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_007370193.1\|4389423_4389699_+	oxidative damage protection protein	NA	NA	NA	NA
WP_007370192.1\|4389804_4390887_+	membrane-bound lytic murein transglycosylase MltC	NA	NA	NA	NA
WP_007370191.1\|4391125_4392379_+	MFS transporter	NA	NA	NA	NA
WP_007370190.1\|4392562_4393393_-	triphosphoribosyl-dephospho-CoA synthase CitG	NA	NA	NA	NA
WP_007370189.1\|4393370_4393910_-	citrate lyase holo-[acyl-carrier protein] synthase	NA	NA	NA	NA
WP_071921399.1\|4393906_4395433_-	citrate lyase subunit alpha	NA	NA	NA	NA
WP_007370187.1\|4395443_4396319_-	citrate (pro-3S)-lyase subunit beta	NA	NA	NA	NA
WP_007370186.1\|4396315_4396609_-	citrate lyase acyl carrier protein	NA	NA	NA	NA
WP_071921400.1\|4396626_4397646_-	[citrate (pro-3S)-lyase] ligase	NA	NA	NA	NA
WP_007370184.1\|4397662_4398532_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_035889290.1\|4398554_4399919_-	2-hydroxycarboxylate transporter family protein	NA	NA	NA	NA
WP_007370182.1\|4400254_4401892_+	sensor histidine kinase	NA	NA	NA	NA
WP_007370181.1\|4401881_4402574_+	response regulator	NA	NA	NA	NA
WP_007370180.1\|4402604_4404740_-	ornithine decarboxylase	NA	NA	NA	NA
WP_007370179.1\|4405140_4405857_+	DUF554 domain-containing protein	NA	NA	NA	NA
WP_071921402.1\|4406316_4407276_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_071921403.1\|4407310_4408894_-	TraI domain-containing protein	NA	NA	NA	NA
WP_071921404.1\|4409101_4409659_+	hypothetical protein	NA	NA	NA	NA
WP_071921405.1\|4409833_4410823_+	hypothetical protein	NA	NA	NA	NA
WP_071921406.1\|4410908_4412120_+	conjugal transfer protein TraF	NA	NA	NA	NA
4411683:4411697	attL	NA	NA	NA	NA
WP_071921407.1\|4412192_4412726_+	hypothetical protein	NA	NA	NA	NA
WP_071921408.1\|4412712_4413255_+	HNH endonuclease	E7EKU5	Edwardsiella_phage	1.3e-47	66.7
WP_071921409.1\|4413239_4413725_+	hypothetical protein	NA	NA	NA	NA
WP_071921410.1\|4413736_4414150_+	hypothetical protein	NA	NA	NA	NA
WP_071921411.1\|4414655_4415243_+\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	5.5e-49	51.9
WP_146159944.1\|4415753_4416302_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_071921413.1\|4416360_4416939_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_083566035.1\|4417087_4417834_+	molecular chaperone	NA	NA	NA	NA
WP_083566037.1\|4417854_4420578_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_071921415.1\|4420574_4421570_+	fimbrial protein	NA	NA	NA	NA
WP_071921416.1\|4421772_4422480_+	response regulator transcription factor	NA	NA	NA	NA
WP_172825178.1\|4422802_4423600_+	fimbrial protein	NA	NA	NA	NA
4422728:4422742	attR	NA	NA	NA	NA
WP_083566040.1\|4423672_4424560_+	EAL domain-containing protein	NA	NA	NA	NA
WP_172825179.1\|4425107_4428875_+	hypothetical protein	Q9LA58	Enterobacterial_phage	9.8e-123	39.1
WP_071921420.1\|4430474_4430996_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_071921421.1\|4430992_4432468_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_071921422.1\|4432531_4433026_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_071921423.1\|4433072_4433480_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_071921424.1\|4433505_4435236_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_071921425.1\|4435199_4436216_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_8

4638629 : 4682037

Erwinia_phage(27.91%)

lysis,head,plate,tRNA,portal,integrase,capsid,terminase,tail,holin

attL 4644734:4644785|attR 4679219:4679270

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071921543.1\|4638629_4639643_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	5.9e-107	58.9
WP_001144069.1\|4639880_4640096_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_035887854.1\|4640266_4642012_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.5e-73	38.4
WP_007370062.1\|4642169_4644014_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-34	33.7
WP_035887857.1\|4644070_4644577_-	G/U mismatch-specific DNA glycosylase	NA	NA	NA	NA
4644734:4644785	attL	NA	NA	NA	NA
WP_071921544.1\|4644922_4645141_-	DNA-binding transcriptional regulator	A0A2I8TV89	Erwinia_phage	2.5e-31	81.9
WP_071921545.1\|4645474_4645909_+	hypothetical protein	NA	NA	NA	NA
WP_071921546.1\|4646232_4646949_+	hypothetical protein	NA	NA	NA	NA
WP_071921547.1\|4647349_4648504_-	phage late control D family protein	Q6K1G4	Salmonella_virus	1.7e-163	77.3
WP_071921548.1\|4648503_4648980_-\|tail	phage tail protein	O64315	Escherichia_phage	1.1e-60	71.3
WP_071921549.1\|4648995_4651437_-\|tail	phage tail tape measure protein	S4TP64	Salmonella_phage	1.4e-260	74.4
WP_071531957.1\|4651429_4651549_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	3.3e-14	87.2
WP_007370054.1\|4651581_4651857_-\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	3.3e-36	86.8
WP_007369252.1\|4651923_4652442_-\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	8.2e-89	92.4
WP_071921550.1\|4652455_4653646_-\|tail	phage tail sheath protein	A0A0F7LBW9	Escherichia_phage	5.0e-206	90.2
WP_071921551.1\|4653916_4654771_+	benzoate transporter	A0A0N9QAD0	Chrysochromulina_ericina_virus	8.6e-27	32.5
WP_071921552.1\|4654795_4655302_-\|tail	tail fiber assembly protein	A0A1S6KZZ1	Salmonella_phage	3.2e-13	30.6
WP_071921553.1\|4655304_4656870_-\|tail	phage tail protein	Q37842	Escherichia_phage	3.8e-89	77.6
WP_035942029.1\|4656880_4657411_-\|tail	phage tail protein I	Q37841	Escherichia_phage	2.2e-89	85.1
WP_071921554.1\|4657403_4658312_-\|plate	baseplate assembly protein	A0A0F7LCJ3	Escherichia_phage	1.0e-134	80.8
WP_071921555.1\|4658316_4658661_-	GPW/gp25 family protein	A0A0F7LDQ1	Escherichia_phage	1.0e-39	71.3
WP_071921899.1\|4658657_4659293_-\|plate	phage baseplate assembly protein V	U5N3F0	Enterobacteria_phage	1.8e-98	85.3
WP_071921900.1\|4659410_4659953_+	hypothetical protein	NA	NA	NA	NA
WP_071921556.1\|4659949_4660351_+	hypothetical protein	NA	NA	NA	NA
WP_071921557.1\|4660351_4660795_-	phage virion morphogenesis protein	O80313	Escherichia_phage	3.6e-45	65.3
WP_071921558.1\|4660787_4661255_-\|tail	phage tail protein	Q7Y4E0	Escherichia_virus	7.2e-68	81.3
WP_071921559.1\|4661217_4661376_-\|lysis	phage lysis protein	A0A218M4L1	Erwinia_phage	6.4e-13	74.0
WP_071921560.1\|4661772_4662282_-	lysozyme	A0A218M4K3	Erwinia_phage	1.1e-69	78.4
WP_007369270.1\|4662265_4662502_-\|holin	holin	A0A218M4L5	Erwinia_phage	1.5e-10	51.7
WP_035889146.1\|4662694_4663201_-\|head	head completion/stabilization protein	M1SNN6	Escherichia_phage	2.7e-68	75.0
WP_071921561.1\|4663298_4664042_-\|terminase	terminase endonuclease subunit	Q94MJ2	Enterobacteria_phage	3.9e-84	68.7
WP_071921562.1\|4664045_4665203_-\|capsid	phage major capsid protein, P2 family	A0A0M4R4W2	Salmonella_phage	5.3e-128	62.3
WP_071921563.1\|4665236_4666097_-\|capsid	GPO family capsid scaffolding protein	Q01088	Escherichia_phage	4.4e-111	72.0
WP_071921564.1\|4666274_4668044_+\|terminase	terminase ATPase subunit family protein	A0A0M4RE51	Salmonella_phage	8.8e-300	84.9
WP_071921565.1\|4668043_4669066_+\|portal	phage portal protein	Q6K1J0	Salmonella_virus	7.9e-152	78.4
WP_071921566.1\|4669115_4670894_-	DUF262 domain-containing protein	A7XFF4	Enterobacteria_phage	2.2e-08	32.5
WP_071921567.1\|4671104_4671524_-	hypothetical protein	Q6K1E9	Salmonella_virus	1.0e-49	67.6
WP_083566050.1\|4671664_4672147_-	DinI-like family protein	A0A218M4I0	Erwinia_phage	7.5e-44	64.0
WP_071921568.1\|4672219_4674442_-	replication endonuclease	A0A218M4H2	Erwinia_phage	0.0e+00	84.8
WP_071921569.1\|4674442_4674664_-	TraR/DksA family transcriptional regulator	A0A0M4S5Q7	Salmonella_phage	1.2e-25	78.1
WP_023327788.1\|4674663_4674891_-	DUF2732 domain-containing protein	F1BUS3	Erwinia_phage	1.7e-22	73.3
WP_007370020.1\|4674958_4675297_-	DUF5347 domain-containing protein	A0A218M4I7	Erwinia_phage	1.2e-45	82.1
WP_071921570.1\|4675260_4675461_-	DUF2724 domain-containing protein	A0A218M4I1	Erwinia_phage	2.1e-24	80.3
WP_071921571.1\|4675468_4675978_-	phage regulatory CII family protein	A0A0M4QWN1	Salmonella_phage	3.4e-79	85.8
WP_001630878.1\|4676008_4676272_-	hypothetical protein	A0A218M4I5	Erwinia_phage	3.1e-44	100.0
WP_071921572.1\|4676404_4676980_+	phage repressor protein CI	A0A218M4J1	Erwinia_phage	4.9e-66	63.8
WP_071921573.1\|4676979_4678020_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	5.5e-185	94.8
WP_071921574.1\|4678007_4679027_+	FRG domain-containing protein	A0A1S6KZX9	Salmonella_phage	2.8e-08	30.1
WP_071921902.1\|4679848_4680787_+	hypothetical protein	NA	NA	NA	NA
4679219:4679270	attR	NA	NA	NA	NA
WP_007370012.1\|4680826_4681219_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_007370011.1\|4681317_4682037_+	SDR family oxidoreductase	M1NMS3	Moumouvirus	5.4e-06	35.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015113

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection