CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017762	Virgibacillus sp. 6R chromosome, complete genome	8 crisprs	cas3,RT,DEDDh,csa3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5,cas14j,casR	0	15	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017762_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_1

2171733-2171964

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCTATATAAGGTGCGACC	PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGACC	CRT

3 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP017762_1

>merge|NZ_CP017762|1|2171733-2171964|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATCCACGCACCTATATAAGGTGCGACCTGACTCGATAGTTCGTGTTGTATTGATACCAGTATTTCAATCCACGCACCTATATAAGGTGCGACCACCGAAGGATAGTATCGGTGCTTCTTTCATATTATTTCAATCCACGCACCTATATAAGGTGCGACCAGAAATGAAAAAAGTAAATTACAACATTAGGATAATTTCAATCCACGCACCTATATAAGGTGCGACT

>NZ_CP017762|1|1|2171733-2171964|PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGACC	TGACTCGATAGTTCGTGTTGTATTGATACCAGT
ATTTCAATCCACGCACCTATATAAGGTGCGACC	ACCGAAGGATAGTATCGGTGCTTCTTTCATATT
ATTTCAATCCACGCACCTATATAAGGTGCGACC	AGAAATGAAAAAAGTAAATTACAACATTAGGATA
ATTTCAATCCACGCACCTATATAAGGTGCGACT

>NZ_CP017762|1|1|2171733-2171963|CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CTGACTCGATAGTTCGTGTTGTATTGATACCAGT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CACCGAAGGATAGTATCGGTGCTTCTTTCATATT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CAGAAATGAAAAAAGTAAATTACAACATTAGGATA
ATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|1|1|2171733-2171964|CRT
ATTTCAATCCACGCACCTATATAAGGTGCGACC	TGACTCGATAGTTCGTGTTGTATTGATACCAGT
ATTTCAATCCACGCACCTATATAAGGTGCGACC	ACCGAAGGATAGTATCGGTGCTTCTTTCATATT
ATTTCAATCCACGCACCTATATAAGGTGCGACC	AGAAATGAAAAAAGTAAATTACAACATTAGGATA
ATTTCAATCCACGCACCTATATAAGGTGCGACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_072741451.1\|2176830_2177541_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP017762.1\|WP_072741450.1\|2174934_2176830_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP017762.1\|WP_072741454.1\|2182332_2183850_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225962
NZ_CP017762.1\|WP_072741441.1\|2161896_2162724_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP017762.1\|WP_072741448.1\|2173459_2174116_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP017762.1\|WP_072741446.1\|2172131_2172422_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP017762.1\|WP_072741445.1\|2170735_2171626_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176112
NZ_CP017762.1\|WP_050350736.1\|2168952_2169525_-\|maltose-O-acetyltransferase	unknown	unknown	gnl\|CDD\|182235
NZ_CP017762.1\|WP_072741442.1\|2163630_2164755_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226359
NZ_CP017762.1\|WP_072741447.1\|2172431_2173463_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP017762.1\|WP_072741453.1\|2178238_2180668_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP017762.1\|WP_050350739.1\|2165439_2166165_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP017762.1\|WP_128743345.1\|2162743_2163634_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP017762.1\|WP_072741443.1\|2167007_2168174_-\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|224828
NZ_CP017762.1\|WP_072741452.1\|2177660_2177927_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP017762.1\|WP_072742411.1\|2160480_2161815_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270451
NZ_CP017762.1\|WP_072741444.1\|2169599_2170619_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_CP017762.1\|WP_072741449.1\|2174105_2174951_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP017762.1\|WP_050350733.1\|2181835_2182333_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225937
NZ_CP017762.1\|WP_050350737.1\|2168498_2168783_-\|phospholipase	unknown	unknown	gnl\|CDD\|153095

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_072741451.1\|2176830_2177541_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.11979e-101
NZ_CP017762.1\|WP_072741450.1\|2174934_2176830_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	1.20382e-179
NZ_CP017762.1\|WP_072741454.1\|2182332_2183850_+\|PH-domain-containing-protein	gnl\|CDD\|225962	COG3428, COG3428, Predicted membrane protein [Function unknown].	7.63578e-51
NZ_CP017762.1\|WP_072741441.1\|2161896_2162724_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.1321e-83
NZ_CP017762.1\|WP_072741448.1\|2173459_2174116_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	7.07861e-26
NZ_CP017762.1\|WP_072741446.1\|2172131_2172422_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.86063e-33
NZ_CP017762.1\|WP_072741445.1\|2170735_2171626_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176112	cd08420, PBP2_CysL_like, C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold. CysL, also known as YwfK, is a regular of sulfur metabolism in Bacillus subtilis. Sulfur is required for the synthesis of proteins and essential cofactors in all living organism. Sulfur can be assimilated either from inorganic sources (sulfate and thiosulfate), or from organic sources (sulfate esters, sulfamates, and sulfonates). CysL activates the transcription of the cysJI operon encoding sulfite reductase, which reduces sulfite to sulfide. Both cysL mutant and cysJI mutant are unable to grow using sulfate or sulfite as the sulfur source. Like other LysR-type regulators, CysL also negatively regulates its own transcription. In Escherichia coli, three LysR-type activators are involved in the regulation of sulfur metabolism: CysB, Cbl and MetR. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.51004e-75
NZ_CP017762.1\|WP_050350736.1\|2168952_2169525_-\|maltose-O-acetyltransferase	gnl\|CDD\|182235	PRK10092, PRK10092, maltose O-acetyltransferase; Provisional.	7.00561e-110
NZ_CP017762.1\|WP_072741442.1\|2163630_2164755_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226359	COG3839, MalK, ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism].	1.17352e-143
NZ_CP017762.1\|WP_072741447.1\|2172431_2173463_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP017762.1\|WP_072741453.1\|2178238_2180668_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.64468e-77
NZ_CP017762.1\|WP_050350739.1\|2165439_2166165_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.29372e-42
NZ_CP017762.1\|WP_128743345.1\|2162743_2163634_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.84573e-91
NZ_CP017762.1\|WP_072741443.1\|2167007_2168174_-\|TraB/GumN-family-protein	gnl\|CDD\|224828	COG1916, COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) [Function unknown].	3.696e-129
NZ_CP017762.1\|WP_072741452.1\|2177660_2177927_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.12812e-09
NZ_CP017762.1\|WP_072742411.1\|2160480_2161815_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.63787e-113
NZ_CP017762.1\|WP_072741444.1\|2169599_2170619_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	1.33745e-90
NZ_CP017762.1\|WP_072741449.1\|2174105_2174951_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	7.12061e-130
NZ_CP017762.1\|WP_050350733.1\|2181835_2182333_+\|PH-domain-containing-protein	gnl\|CDD\|225937	COG3402, COG3402, Uncharacterized conserved protein [Function unknown].	8.85074e-29
NZ_CP017762.1\|WP_050350737.1\|2168498_2168783_-\|phospholipase	gnl\|CDD\|153095	cd04706, PLA2_plant, PLA2_plant: Plant-specific sub-family of Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids; secreted PLA2s have also been found to specifically bind to a variety of soluble and membrane proteins in mammals, including receptors. As a toxin, PLA2 is a potent presynaptic neurotoxin which blocks nerve terminals by binding to the nerve membrane and hydrolyzing stable membrane lipids. The products of the hydrolysis cannot form bilayers leading to a change in membrane conformation and ultimately to a block in the release of neurotransmitters. PLA2 may form dimers or oligomers. This sub-family does not appear to have a conserved active site and metal-binding loop.	1.02198e-05

>NZ_CP017762.1|WP_072741445.1|2170735_2171626_+|LysR-family-transcriptional-regulator
MYYDALRTFITLAEVKNFTKAAEILHISQPSVSLHIKNLERELETELVVRSRKSLKLSPTGAILYERAKQIIRIYEQTKRDILEQQQIVKGCLKIGASFTIGEYILPDLLVDVHAAYPELELKVVIGNTEEIVQQVKHFQVDIGFIEGQTSDKELVVQPFMKDELWVVAPVSHELSQKEEITTSDLQNQSWISREEGSGTREYLEHVIRSNGLQVKSFLTISSNQGVKESVIKGMGLSLLSHSVIERDVQLEQLTTLQLKDIHFKRMFSCVYSPIMKSKQNVAIFMDMLKEKWPYS
>NZ_CP017762.1|WP_072741444.1|2169599_2170619_-|YeiH-family-putative-sulfate-export-transporter
MGNTVGQKKTNRIAFFQGIGITLIIAIIANYAAKLPFLSIMGQLVIAIIIGMIWKQAIGVPSHLQKGVTFSNKKLLRLGIILLGMRLNLIDIYQAGISVFLIAAICLVFTLFVVYGLTRWFGVGKRLGILTACGTAICGAAAVVAVAPQVKAKDEETAVGAATVAVLGTIFTLIYSVIYSILNLSPTGYGIFTGATLHEIAHVIAAADVGGSEAVDLAVIVKLTRVALLVPVVIVVGYMFQRSGESTNKKVSMSIIPWFILGFLAMSGFNTLGIVSESVANTIVTVAYLLIAMAMAGLGLNVELKTFRRLGMKSFAAGMVGSVLLVILGYSLVMLFQLN
>NZ_CP017762.1|WP_050350736.1|2168952_2169525_-|maltose-O-acetyltransferase
MTTEKEKMIAGELYNPSDQTLVHDRESCRMKTRLFNQTLETDLEERKKLLQDLLGSTGEDIYIEPTFRCDYGYNIYIGNHFYANFDCVMLDVCKIRIGNNCMLAPGVHIYTATHPLDPHARNSGKELGKPVTIGDNVWIGGRAVINPGVTIGNNAVIASGSVVVKDVPANTVVGGNPARVLKKIRTPNNV
>NZ_CP017762.1|WP_050350737.1|2168498_2168783_-|phospholipase
MRHQRETTSCFPDGYRWCGPGCSGPGEPINDVDAICKAHDMCYRRSRDYCKCDKAFLEHMRLKIDPRTAKGRHARTMYNYMRLQSLFTCGFRRF
>NZ_CP017762.1|WP_072741443.1|2167007_2168174_-|TraB/GumN-family-protein
MTEDNITRIYMDDKEYILIGTAHVSKHSAEQVKEVIEAENPDAVCVELDEQRYQSVKDDNKWKNMDIFKVIKEKKASLLLMNLAISSFQKRMAKQFGINPGQEMIQGIESAEQVNAKLVLADRNIQITFARIWNNIGLKGKAMLLTQVIASIFSKETISEEELEKMKQQDTIHTILQEFTDSFPRLKKPLIDERDQYLAQKIKEAPGNKIVAVLGAAHVPGIKEQIQKDHDLSKLREVPPKSKWPKIIGWSIPVLILAIIAYTFYANPQAGWEQTLSWIIWNGGLSAIGALIALGHPLTILTALIAAPITSLNPLLAAGWFAGFVQAYVKRPHVRDFETLSEDVFTVKGFWRNKVTRVLLIVVLANIGSSLGTFIGGVDVIRVFLENL
>NZ_CP017762.1|WP_050350739.1|2165439_2166165_-|GntR-family-transcriptional-regulator
MPVDKEMQIIDDIMEKIITKAMKPGEKIPSENKLADQHKVPRITARKALTTLEARGYIYSVQGKGRFLKETSKPIQLHLTGNSSFTDKMKRAGYRLTTKNMYCNKINYDSKIYDTLQANREAAIYKIGRLRLIDDEPIAIHQSFVDQDRFPNIAHEGSQILSMFAYYRQFGYEEFASKHSLLSITFPTSYEQELLSCSSMVPLIVLETDCIDRKTKKVLEYTKILYRSDKFKYDITSEGSR
>NZ_CP017762.1|WP_072741442.1|2163630_2164755_-|ABC-transporter-ATP-binding-protein
MNITLNNISMQFAEVTAVDRLSVTIEEGSLVSLLGPSGCGKSTTLFMLAGLYQPTSGELYFGEQLMNKVSPEKRQIGMVFQNYALYPHMTVLKNIMFPLKMAKVAKKEARESAIAMAELVQIGHLLERKPSQLSGGQQQRVAIARALVKKPKLLLLDEPLSNLDARLRLEMREEIRRIQQTIGITTVFVTHDQEEALSISDKILLMKDGKYQQYSDAREIYEYPQNEFVGRFLGNPPMNQLPAVLETNKQFVRLEDTDQRIAITKQVTREVEPQEQVIVGVRPEDLFVQSENEQGGITGETMMVERIGRDNLLNIQVGKRKIRAIVSPDTEVTIGKKVTLGIRPGYCHLFHADTGESLLMDEPIHSALKERVTC
>NZ_CP017762.1|WP_128743345.1|2162743_2163634_-|sugar-ABC-transporter-permease
MNEKPTWEKTLKAGLYLLPALLIIGVFNLYPIVKSFFMSFYTDYDYFEDTVYERGLDNYTYIFTDEAFWESMSNTFIYVLGVVPISIVLSLGIAIMLNQSIRLRGLFRTIYFIPFVTSVVAVSIVWRWIFHTEYGVLNYFLGFFGINAIEWLTDPQWAMPSLIILAVWKGLGYNIIIFLAGLQNVSKQYYLAAQIDGASKWERFKNVTVPLISPTTFFISIVSIINAFKVFDEVFALFGGQPGPAGSAQTIVYYIFNRFYQDWDFGVASAAAYMLFLVIFVFTLIQLYVGKKKVNY
>NZ_CP017762.1|WP_072741441.1|2161896_2162724_-|carbohydrate-ABC-transporter-permease
MVKKEAMSKGFIYILLTLGAILMLLPFAWMISTSLKSANEVMIMPPKWIPTDIQWENYTKAFEVAPFARYAFNSIVVLVLSTLGELITTILAAYAFSRINFYGKNIVFAVLLGTMMVPGEVLLTPNFVTLVHLGWIDQYEALIVPWIASIFSIFLLRQFFLSIPEELAYASKIDGCNDFKFLWTIMVPLAKPALITITLLKAIGSWNAFLWPLIVTNSEEMRTLPVGLTAFSTETGTVYELLMAASTMIILPMIILYIILQKYIIEGVAKAGVKG
>NZ_CP017762.1|WP_072742411.1|2160480_2161815_-|ABC-transporter-substrate-binding-protein
MKKIIMFLVITMQIMVLAACGNEEKQKEDKEAEKATATSIPDSLEEPVEIEFWHAMTGGLEETLKTITDEFNQSQENIEVTLVSQGSYGDLSQKLMASAKAGDVPVMTQAYEDWMTQYIDNDLIADLTPYIEHEKHGWSEDELNDIVEVFRKANTWEDKMYGVPFNKSTEVLYYNEDMLADNDLEVPTTWEEYKQAAEKLTTEKDGTSIVGLGFENSIGLSFPTYVRQTGGKTIDAEENKVTFDTPEAKTALEFLNGMVAAGHARLAGEDGYMSGPFGRGDVAMYVGSSAGISFVGAEAESKINWSVAPLPKGKEAATAFQGTNLTMFNSASEEEKLAAWEYMKFLTSKEQTVYWAKSTGYVPVRDSALNTDEWKQYIQENPEFGVAASQFDAGYYDPNIKGKSGIQEVLDKEIQAVLLQEKTVEDGLKDIQKDAQNAVDKANK
>NZ_CP017762.1|WP_072741446.1|2172131_2172422_-|CRISPR-associated-endonuclease-Cas2
MLVLVTYDVNTSSNGGRKRLRKVSKVCQNYGQRVQNSVFECIVDDAQFAALKIQLTGLIDEEKDSLRFYRLGNNYKTKVEHIGTKEAINLEDPLIF
>NZ_CP017762.1|WP_072741447.1|2172431_2173463_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLLNTLFITQPDVYLSLDGDNIVLLKEQEKLGRLPLHNLESIVSFGYTGASPALMGYCAKRNISLVFMTINGSFLARVIGESKGNVVLRKRQYQLSEDEAQSAIIASNFIVGKIFNHKWMIERMTRDYPLRIDLVAFKEVSAQLSNMMQEVRDCHDLESLRGWEGQAAFSYNKIFDQMILQQKEDFFFHSRSRRPPLDKVNAMLSFAYTLLANDMAAALESVGLDAYVGFLHRDRPGRASLALDVMEELRGIYADRFVISLINKKAIKEGDFLHKENGAVIMTNDGRKKFLSAWQTKKQEKITHPYLGEKITWGLVPYAQSLLLARYLRGDLDEYPPFLWK
>NZ_CP017762.1|WP_072741448.1|2173459_2174116_-|CRISPR-associated-protein-Cas4
MVNKEEAFLMLSGIQHFEFCRRQWALIHIEQQWEENGKTIEGHYLHRKADEPMIREKRGNKLIIRALPVKSKSLKINGVCDVVEFIQHSNGIEIHGEEGRHLPFPVEYKRGRPKKDDADILQLTAQAICLEEMLLCQIEKGYMYYHEIKHRVEVPFTNYLRQKVKDISAEMHDYYQRRHTPKVKTGSFCKSCSLQHICLPKLMNKRSVKSYIEGKINE
>NZ_CP017762.1|WP_072741449.1|2174105_2174951_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTTLDKKIDFAVVLSVNNANPNGDPLNGNRPRQNYDGHGEISDVAIKRKIRNRLLDMGENVFVQSNDYKVDNFKSLKERADAHEELNKASKAKDNEAYARLACEEWIDVRSFGQVFAFKNVDVSVGVRGPVSIHTATSVDPVDITSMQITKSVNSVTGDKKGSDTMGMKHRVNFGLYVFYGSINTQLAEKTGFSNEDAEKLKQALVHLFENDASSARPDGSMEVHHVYWWEHNSKLGQYSSAKVHRTVKIEPKVESPKSYDDYSITVKELDGLPVEVMDGK
>NZ_CP017762.1|WP_072741450.1|2174934_2176830_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLNQLYETYEANLDRVGEIEKTRGNKSYTLLPISHTTQNAHIEVTVTEDGEFHSAIVLDKVNTLIPTTESSASRSGSKVAPYPLHDKLSYVAGDFVKYGGKIKKEEPFASYIEQLEDWATSPYGHPKVKSIFKYLQKKQLIKDLVAANIIFLDEQNQLIGKWNKKYEALHGEKPAVFSAITGGQESAFVRFNVYSPAKHLTDVWDDKEVYDSFISYYNNLVGEKDICFVTGTWQASTERHANKIRHAADKAKLISANDTSGFTFRGRFKESMEAASISYEVSQKAHNALKWLILRQGYMIDERVFLVWGNDQLQTVMPIDDTYSIHPTAAVVKESKTNTLDHFANEVAKAFAGYKHDLSTTSNVTILILDSATTGRLGVLYYRNMNKELYLQRLEHWHSTCVWEHRYRKNDDGKFVKFFGAPATKDIAFAAYGTRASEKIVKDLMSRMLPCIVDNRKIPTDIVNSAFYRASNPVAMEKWEWEKTLSIACALINKREGLDVALDHELNDRDYLFGRLLALADVLERRALDQDETRATNAIRYMNAFSKHPARTWKTLQESIQPYQARLGKRGNYLASLIDEVGSRLTIEDFNDKPLSGKYLLGFYSQRRDLYQKKTVENNSEENGNDDIR
>NZ_CP017762.1|WP_072741451.1|2176830_2177541_-|type-I-C-CRISPR-associated-protein-Cas5
MRNAIEFEVWGDYALFTDPLTKIGGEKLTYQVPTYQALKGIVESVYWKPTIVMIVDAVRIMNPIQMESKGIRPIEYKGGNTLANYTYLKQPRYQVKAHFEFNLHRPDMAFDRNENKHYSIMKRALKVGGRRDVFLGARECQAYVEPCVFGEGEGFYDNYEELHFGTMVHGINYPDETGDNQMEVRLWNAVMKHGVITFPRPEECNLTRPIKQMKVKQFNETNVQSADALLNELGGE
>NZ_CP017762.1|WP_072741452.1|2177660_2177927_-|transposase
MQRIRRTFTDEFKIKIVKLYESGKTKKDIISEHNLSLSTLNNWIRLYKNPFIKNNWDENEINELYKENQRLQLENSILKEAAIILSRK
>NZ_CP017762.1|WP_072741453.1|2178238_2180668_-|CRISPR-associated-helicase/endonuclease-Cas3
MDFIAHIRQSDSEVQTVKDHLLEVRELAEQYGEPIGIKHLCGLAGLLHDFGKYSNEFREYIIAAINTPEDAPKRGSVDHSTGGAKLLYELLHTKNMTPGKALVAEVVGNAIISHHSYLHDFLTPELESKYLNRVRDKPLHEFDQMVEKFFVNVMNENDFDQYIEKAIQELLLIIQSVPKEDAEQQLMFITKFVFSALIDADRTNTRLFEENKTLSRMDHMALFEKYYKRLHEKITIFQNHPNANTPINQLRSKMSEQCEVAAEKESGIYTLSIPTGGGKTLASLRYGLKHALLHHKKRIIYVVPFTTIIEQNAEEVRSILKDTENILEHHSNVILDDDDNDEYLDGTVTEKQKLKLAKDNWDAPIIFTTMVQFLNVFYAKGSRNIRRLHHLSEAVIIFDEVQKVPVKCISLFNEALNFLKNYCKSSILLCTATQPALDFVQNKLEIHTDAEIVENLTDVVDAFKRVEIIDKATDKAVSTNDLVSFIDQQLEHVQSVLVVLNTKKVVKTLYERLQQNRSDETHIYHLSTSMCAAHRNDILSKLREDLDNKIPVICISTQLIEAGVDISFDCVIRSLAGLDSIAQAAGRCNRHGEKDIQQVYVIDHQEEQLKFLKEIEIGKQITRRILIDMKRNQNEHGGNILSPQAMERYFQELYLAFANDLNYFIPALKKDMMELLTSSKDKFSYVQAYRSKYNAEVPLFITNSYRTAAEHFRVIDNQTTSVIVPYEHGGKEIITELSGNISMEELARIMRYAQHYTINLYKYELDLVMKNNRLVSFFDGKIYALAEGAYSNEFGFDVEGDSADEVYMI
>NZ_CP017762.1|WP_050350733.1|2181835_2182333_+|PH-domain-containing-protein
MYQHIEEPKQKISQHAINVWRITNTIGHFIFLIIIIVLLTLHANFEWYGWIGYVLWILLGLDIISAIWSVFFEPILLQKYWRYGINKDFVQLKHGKWNMEHQVIPMTKIQYVSLKQGPILRKYGLSSVSIGTMASTHEIPAIQEDEAKTIRDEIAALAKIKEVEN
>NZ_CP017762.1|WP_072741454.1|2182332_2183850_+|PH-domain-containing-protein
METNKRMHPMMMLVSFIASLKDIFFIFIFLFVINLSSTATWVEIGRILFFVYLIYKVFSVIITWWRTTYSVNESFIEIKQGIFTRKQHQIPFDRIQNVQTNTPFYLRPLNLTALTLETGAEDEDSSFTFTAISKQEAEQIEHVLDYYTKQQGQEPETTETNETETADSNAQPVMKDKRIVHFNPTKKDVLKASALSFSYLLLIPVLASLLSNIDEVYDLSETGEKIFHFLRESWFWLSVLIFMFIIIAIGFGLVRTYLKYGRYEISSDQERIYIRKGVWNEQHFSIRKQNVQAAHIEQSLLKRMLRIAEVKLISAGGVDLSGEEINSLYPFLPINRAHHMIEEILPEFAIKAGMEQLPKKSLVARICQIPLLWITGTAIIVIFFPKWWPVSIILFLLTIASRILDYYFTCYLIHGEILQIRTGGFFITTSITTREKIIEFKLEQNLIQKRFGLADIETTNRSKPIHVNALYNIPIDMVQRTFAWYTGRSPKIEGGSYGEQDLYRR

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Crispr_ID: NZ_CP017762_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_2

2181045-2181275

TypeI

I-C

Consensus_repeat	Method
TATTTCAATCCACGCACCTACATAAGGTGCGACGTT	PILER-CR
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	CRISPRCasFinder
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	CRT

3 spacers

cas3,cas5,cas8c,cas7,cas4,cas1,cas2

The CRISPR arrays of NZ_CP017762_2

>merge|NZ_CP017762|2|2181045-2181275|PILER-CR,CRISPRCasFinder,CRT
GTCGCACCTTATGTAGGTGCGTGGATTGAAATACCCCTAAAAAATAATGATTGAAACTCTACATCGTCGCACCTTATGTAGGTGCGTGGATTGAAATATGTAAAATCCTCCTAATTTTAATTTTTTAAAGGTCGCACCTTATGTAGGTGCGTGGATTGAAATATTTGAATGAATGGGGAACGGTTAAAAACCCGAACCGTCGCACCTTATATAGGTGTTTGGGCTCTAAAG

>NZ_CP017762|2|2|2181045-2181207|PILER-CR
GTCGCACCTTATGTAGGTGCGTGGATTGAAATACCC	CTAAAAAATAATGATTGAAACTCTACATC
GTCGCACCTTATGTAGGTGCGTGGATTGAAATATGT	AAAATCCTCCTAATTTTAATTTTTTAAAG
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA

>NZ_CP017762|2|2|2181045-2181275|CRISPRCasFinder
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	CCCCTAAAAAATAATGATTGAAACTCTACATC
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	TGTAAAATCCTCCTAATTTTAATTTTTTAAAG
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	TTTGAATGAATGGGGAACGGTTAAAAACCCGAACC
GTCGCACCTTATATAGGTGTTTGGGCTCTAAAG

>NZ_CP017762|2|2|2181045-2181275|CRT
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	CCCCTAAAAAATAATGATTGAAACTCTACATC
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	TGTAAAATCCTCCTAATTTTAATTTTTTAAAG
GTCGCACCTTATGTAGGTGCGTGGATTGAAATA	TTTGAATGAATGGGGAACGGTTAAAAACCCGAACC
GTCGCACCTTATATAGGTGTTTGGGCTCTAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_072741454.1\|2182332_2183850_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225962
NZ_CP017762.1\|WP_072741448.1\|2173459_2174116_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP017762.1\|WP_072741452.1\|2177660_2177927_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP017762.1\|WP_072741445.1\|2170735_2171626_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176112
NZ_CP017762.1\|WP_072741446.1\|2172131_2172422_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP017762.1\|WP_072741447.1\|2172431_2173463_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP017762.1\|WP_072741455.1\|2183821_2184334_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741449.1\|2174105_2174951_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP017762.1\|WP_072741450.1\|2174934_2176830_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP017762.1\|WP_072741456.1\|2188347_2188974_+\|LysE-family-transporter	unknown	unknown	gnl\|CDD\|280058
NZ_CP017762.1\|WP_072741451.1\|2176830_2177541_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP017762.1\|WP_050350730.1\|2184604_2185423_-\|formate/nitrite-transporter-family-protein	unknown	unknown	gnl\|CDD\|376497
NZ_CP017762.1\|WP_050350725.1\|2189115_2189874_+\|YqcI/YcgG-family-protein	unknown	unknown	gnl\|CDD\|370174
NZ_CP017762.1\|WP_072741453.1\|2178238_2180668_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP017762.1\|WP_050350729.1\|2185755_2186319_-\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319825
NZ_CP017762.1\|WP_072741444.1\|2169599_2170619_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_CP017762.1\|WP_050350728.1\|2186385_2187348_-\|D-2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240625
NZ_CP017762.1\|WP_050350723.1\|2190275_2191229_-\|arginine-deiminase	unknown	unknown	gnl\|CDD\|224747
NZ_CP017762.1\|WP_050350733.1\|2181835_2182333_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225937
NZ_CP017762.1\|WP_050350727.1\|2187505_2187898_-\|SLAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|275191

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_072741454.1\|2182332_2183850_+\|PH-domain-containing-protein	gnl\|CDD\|225962	COG3428, COG3428, Predicted membrane protein [Function unknown].	7.63578e-51
NZ_CP017762.1\|WP_072741448.1\|2173459_2174116_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	7.07861e-26
NZ_CP017762.1\|WP_072741452.1\|2177660_2177927_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.12812e-09
NZ_CP017762.1\|WP_072741445.1\|2170735_2171626_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176112	cd08420, PBP2_CysL_like, C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold. CysL, also known as YwfK, is a regular of sulfur metabolism in Bacillus subtilis. Sulfur is required for the synthesis of proteins and essential cofactors in all living organism. Sulfur can be assimilated either from inorganic sources (sulfate and thiosulfate), or from organic sources (sulfate esters, sulfamates, and sulfonates). CysL activates the transcription of the cysJI operon encoding sulfite reductase, which reduces sulfite to sulfide. Both cysL mutant and cysJI mutant are unable to grow using sulfate or sulfite as the sulfur source. Like other LysR-type regulators, CysL also negatively regulates its own transcription. In Escherichia coli, three LysR-type activators are involved in the regulation of sulfur metabolism: CysB, Cbl and MetR. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.51004e-75
NZ_CP017762.1\|WP_072741446.1\|2172131_2172422_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.86063e-33
NZ_CP017762.1\|WP_072741447.1\|2172431_2173463_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP017762.1\|WP_072741449.1\|2174105_2174951_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	7.12061e-130
NZ_CP017762.1\|WP_072741450.1\|2174934_2176830_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	1.20382e-179
NZ_CP017762.1\|WP_072741456.1\|2188347_2188974_+\|LysE-family-transporter	gnl\|CDD\|280058	pfam01810, LysE, LysE type translocator. This family consists of various hypothetical proteins and an l-lysine exporter LysE from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators. LysE exports l-lysine from the cell into the surrounding medium and is predicted to span the membrane six times. The physiological function of the exporter is to excrete excess l-Lysine as a result of natural flux imbalances or peptide hydrolysis; and also after artificial deregulation of l-Lysine biosynthesis as used by the biotechnology. industry for the production of l-lysine.	1.49762e-33
NZ_CP017762.1\|WP_072741451.1\|2176830_2177541_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.11979e-101
NZ_CP017762.1\|WP_050350730.1\|2184604_2185423_-\|formate/nitrite-transporter-family-protein	gnl\|CDD\|376497	pfam01226, Form_Nir_trans, Formate/nitrite transporter.	1.17407e-73
NZ_CP017762.1\|WP_050350725.1\|2189115_2189874_+\|YqcI/YcgG-family-protein	gnl\|CDD\|370174	pfam08892, YqcI_YcgG, YqcI/YcgG family. This family of proteins are functionally uncharacterized. The family include YqcI and YcgG from B. subtilis. The alignment contains a conserved FPC motif at the N-terminus and CPF at the C-terminus.	7.7676e-95
NZ_CP017762.1\|WP_072741453.1\|2178238_2180668_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.64468e-77
NZ_CP017762.1\|WP_050350729.1\|2185755_2186319_-\|HAD-IA-family-hydrolase	gnl\|CDD\|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.59744e-47
NZ_CP017762.1\|WP_072741444.1\|2169599_2170619_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	1.33745e-90
NZ_CP017762.1\|WP_050350728.1\|2186385_2187348_-\|D-2-hydroxyacid-dehydrogenase	gnl\|CDD\|240625	cd05300, 2-Hacid_dh_1, Putative D-isomer specific 2-hydroxyacid dehydrogenase. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomains but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric. Formate dehydrogenase (FDH) catalyzes the NAD+-dependent oxidation of formate ion to carbon dioxide with the concomitant reduction of NAD+ to NADH. FDHs of this family contain no metal ions or prosthetic groups. Catalysis occurs though direct transfer of the hydride ion to NAD+ without the stages of acid-base catalysis typically found in related dehydrogenases. FDHs are found in all methylotrophic microorganisms in energy production and in the stress responses of plants.	2.6777e-141
NZ_CP017762.1\|WP_050350723.1\|2190275_2191229_-\|arginine-deiminase	gnl\|CDD\|224747	COG1834, COG1834, N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism].	2.00402e-19
NZ_CP017762.1\|WP_050350733.1\|2181835_2182333_+\|PH-domain-containing-protein	gnl\|CDD\|225937	COG3402, COG3402, Uncharacterized conserved protein [Function unknown].	8.85074e-29
NZ_CP017762.1\|WP_050350727.1\|2187505_2187898_-\|SLAP-domain-containing-protein	gnl\|CDD\|275191	TIGR04398, hypothetical_protein, SLAP domain. This domain is duplicated in SlaP (S-layer assembly protein), a partner of SecA2 in the Bacillus anthracis type of accessory Sec system (see TIGR04397). The domain is found, either once or twice, in additional Firmicutes species.	1.38947e-15

>NZ_CP017762.1|WP_072741453.1|2178238_2180668_-|CRISPR-associated-helicase/endonuclease-Cas3
MDFIAHIRQSDSEVQTVKDHLLEVRELAEQYGEPIGIKHLCGLAGLLHDFGKYSNEFREYIIAAINTPEDAPKRGSVDHSTGGAKLLYELLHTKNMTPGKALVAEVVGNAIISHHSYLHDFLTPELESKYLNRVRDKPLHEFDQMVEKFFVNVMNENDFDQYIEKAIQELLLIIQSVPKEDAEQQLMFITKFVFSALIDADRTNTRLFEENKTLSRMDHMALFEKYYKRLHEKITIFQNHPNANTPINQLRSKMSEQCEVAAEKESGIYTLSIPTGGGKTLASLRYGLKHALLHHKKRIIYVVPFTTIIEQNAEEVRSILKDTENILEHHSNVILDDDDNDEYLDGTVTEKQKLKLAKDNWDAPIIFTTMVQFLNVFYAKGSRNIRRLHHLSEAVIIFDEVQKVPVKCISLFNEALNFLKNYCKSSILLCTATQPALDFVQNKLEIHTDAEIVENLTDVVDAFKRVEIIDKATDKAVSTNDLVSFIDQQLEHVQSVLVVLNTKKVVKTLYERLQQNRSDETHIYHLSTSMCAAHRNDILSKLREDLDNKIPVICISTQLIEAGVDISFDCVIRSLAGLDSIAQAAGRCNRHGEKDIQQVYVIDHQEEQLKFLKEIEIGKQITRRILIDMKRNQNEHGGNILSPQAMERYFQELYLAFANDLNYFIPALKKDMMELLTSSKDKFSYVQAYRSKYNAEVPLFITNSYRTAAEHFRVIDNQTTSVIVPYEHGGKEIITELSGNISMEELARIMRYAQHYTINLYKYELDLVMKNNRLVSFFDGKIYALAEGAYSNEFGFDVEGDSADEVYMI
>NZ_CP017762.1|WP_072741452.1|2177660_2177927_-|transposase
MQRIRRTFTDEFKIKIVKLYESGKTKKDIISEHNLSLSTLNNWIRLYKNPFIKNNWDENEINELYKENQRLQLENSILKEAAIILSRK
>NZ_CP017762.1|WP_072741451.1|2176830_2177541_-|type-I-C-CRISPR-associated-protein-Cas5
MRNAIEFEVWGDYALFTDPLTKIGGEKLTYQVPTYQALKGIVESVYWKPTIVMIVDAVRIMNPIQMESKGIRPIEYKGGNTLANYTYLKQPRYQVKAHFEFNLHRPDMAFDRNENKHYSIMKRALKVGGRRDVFLGARECQAYVEPCVFGEGEGFYDNYEELHFGTMVHGINYPDETGDNQMEVRLWNAVMKHGVITFPRPEECNLTRPIKQMKVKQFNETNVQSADALLNELGGE
>NZ_CP017762.1|WP_072741450.1|2174934_2176830_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLNQLYETYEANLDRVGEIEKTRGNKSYTLLPISHTTQNAHIEVTVTEDGEFHSAIVLDKVNTLIPTTESSASRSGSKVAPYPLHDKLSYVAGDFVKYGGKIKKEEPFASYIEQLEDWATSPYGHPKVKSIFKYLQKKQLIKDLVAANIIFLDEQNQLIGKWNKKYEALHGEKPAVFSAITGGQESAFVRFNVYSPAKHLTDVWDDKEVYDSFISYYNNLVGEKDICFVTGTWQASTERHANKIRHAADKAKLISANDTSGFTFRGRFKESMEAASISYEVSQKAHNALKWLILRQGYMIDERVFLVWGNDQLQTVMPIDDTYSIHPTAAVVKESKTNTLDHFANEVAKAFAGYKHDLSTTSNVTILILDSATTGRLGVLYYRNMNKELYLQRLEHWHSTCVWEHRYRKNDDGKFVKFFGAPATKDIAFAAYGTRASEKIVKDLMSRMLPCIVDNRKIPTDIVNSAFYRASNPVAMEKWEWEKTLSIACALINKREGLDVALDHELNDRDYLFGRLLALADVLERRALDQDETRATNAIRYMNAFSKHPARTWKTLQESIQPYQARLGKRGNYLASLIDEVGSRLTIEDFNDKPLSGKYLLGFYSQRRDLYQKKTVENNSEENGNDDIR
>NZ_CP017762.1|WP_072741449.1|2174105_2174951_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTTLDKKIDFAVVLSVNNANPNGDPLNGNRPRQNYDGHGEISDVAIKRKIRNRLLDMGENVFVQSNDYKVDNFKSLKERADAHEELNKASKAKDNEAYARLACEEWIDVRSFGQVFAFKNVDVSVGVRGPVSIHTATSVDPVDITSMQITKSVNSVTGDKKGSDTMGMKHRVNFGLYVFYGSINTQLAEKTGFSNEDAEKLKQALVHLFENDASSARPDGSMEVHHVYWWEHNSKLGQYSSAKVHRTVKIEPKVESPKSYDDYSITVKELDGLPVEVMDGK
>NZ_CP017762.1|WP_072741448.1|2173459_2174116_-|CRISPR-associated-protein-Cas4
MVNKEEAFLMLSGIQHFEFCRRQWALIHIEQQWEENGKTIEGHYLHRKADEPMIREKRGNKLIIRALPVKSKSLKINGVCDVVEFIQHSNGIEIHGEEGRHLPFPVEYKRGRPKKDDADILQLTAQAICLEEMLLCQIEKGYMYYHEIKHRVEVPFTNYLRQKVKDISAEMHDYYQRRHTPKVKTGSFCKSCSLQHICLPKLMNKRSVKSYIEGKINE
>NZ_CP017762.1|WP_072741447.1|2172431_2173463_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLLNTLFITQPDVYLSLDGDNIVLLKEQEKLGRLPLHNLESIVSFGYTGASPALMGYCAKRNISLVFMTINGSFLARVIGESKGNVVLRKRQYQLSEDEAQSAIIASNFIVGKIFNHKWMIERMTRDYPLRIDLVAFKEVSAQLSNMMQEVRDCHDLESLRGWEGQAAFSYNKIFDQMILQQKEDFFFHSRSRRPPLDKVNAMLSFAYTLLANDMAAALESVGLDAYVGFLHRDRPGRASLALDVMEELRGIYADRFVISLINKKAIKEGDFLHKENGAVIMTNDGRKKFLSAWQTKKQEKITHPYLGEKITWGLVPYAQSLLLARYLRGDLDEYPPFLWK
>NZ_CP017762.1|WP_072741446.1|2172131_2172422_-|CRISPR-associated-endonuclease-Cas2
MLVLVTYDVNTSSNGGRKRLRKVSKVCQNYGQRVQNSVFECIVDDAQFAALKIQLTGLIDEEKDSLRFYRLGNNYKTKVEHIGTKEAINLEDPLIF
>NZ_CP017762.1|WP_072741445.1|2170735_2171626_+|LysR-family-transcriptional-regulator
MYYDALRTFITLAEVKNFTKAAEILHISQPSVSLHIKNLERELETELVVRSRKSLKLSPTGAILYERAKQIIRIYEQTKRDILEQQQIVKGCLKIGASFTIGEYILPDLLVDVHAAYPELELKVVIGNTEEIVQQVKHFQVDIGFIEGQTSDKELVVQPFMKDELWVVAPVSHELSQKEEITTSDLQNQSWISREEGSGTREYLEHVIRSNGLQVKSFLTISSNQGVKESVIKGMGLSLLSHSVIERDVQLEQLTTLQLKDIHFKRMFSCVYSPIMKSKQNVAIFMDMLKEKWPYS
>NZ_CP017762.1|WP_072741444.1|2169599_2170619_-|YeiH-family-putative-sulfate-export-transporter
MGNTVGQKKTNRIAFFQGIGITLIIAIIANYAAKLPFLSIMGQLVIAIIIGMIWKQAIGVPSHLQKGVTFSNKKLLRLGIILLGMRLNLIDIYQAGISVFLIAAICLVFTLFVVYGLTRWFGVGKRLGILTACGTAICGAAAVVAVAPQVKAKDEETAVGAATVAVLGTIFTLIYSVIYSILNLSPTGYGIFTGATLHEIAHVIAAADVGGSEAVDLAVIVKLTRVALLVPVVIVVGYMFQRSGESTNKKVSMSIIPWFILGFLAMSGFNTLGIVSESVANTIVTVAYLLIAMAMAGLGLNVELKTFRRLGMKSFAAGMVGSVLLVILGYSLVMLFQLN
>NZ_CP017762.1|WP_050350733.1|2181835_2182333_+|PH-domain-containing-protein
MYQHIEEPKQKISQHAINVWRITNTIGHFIFLIIIIVLLTLHANFEWYGWIGYVLWILLGLDIISAIWSVFFEPILLQKYWRYGINKDFVQLKHGKWNMEHQVIPMTKIQYVSLKQGPILRKYGLSSVSIGTMASTHEIPAIQEDEAKTIRDEIAALAKIKEVEN
>NZ_CP017762.1|WP_072741454.1|2182332_2183850_+|PH-domain-containing-protein
METNKRMHPMMMLVSFIASLKDIFFIFIFLFVINLSSTATWVEIGRILFFVYLIYKVFSVIITWWRTTYSVNESFIEIKQGIFTRKQHQIPFDRIQNVQTNTPFYLRPLNLTALTLETGAEDEDSSFTFTAISKQEAEQIEHVLDYYTKQQGQEPETTETNETETADSNAQPVMKDKRIVHFNPTKKDVLKASALSFSYLLLIPVLASLLSNIDEVYDLSETGEKIFHFLRESWFWLSVLIFMFIIIAIGFGLVRTYLKYGRYEISSDQERIYIRKGVWNEQHFSIRKQNVQAAHIEQSLLKRMLRIAEVKLISAGGVDLSGEEINSLYPFLPINRAHHMIEEILPEFAIKAGMEQLPKKSLVARICQIPLLWITGTAIIVIFFPKWWPVSIILFLLTIASRILDYYFTCYLIHGEILQIRTGGFFITTSITTREKIIEFKLEQNLIQKRFGLADIETTNRSKPIHVNALYNIPIDMVQRTFAWYTGRSPKIEGGSYGEQDLYRR
>NZ_CP017762.1|WP_072741455.1|2183821_2184334_+|hypothetical-protein
MENKIYIEDNFFSAGRTAIRNHHNEKIGDLDLKTAFSSSINVYDSQGTRLAEGKFKSSFSSQWVVIDATAEIIGTLKANWFSFKKKYTYTLKNGHEYTITSPVFSKTFTMTGEQEREIVASFTRVSSFFSSPAYELINHTDRLSMEEFIVVVMGVNAIEKSQAAASSGGS
>NZ_CP017762.1|WP_050350730.1|2184604_2185423_-|formate/nitrite-transporter-family-protein
MESQPIEQAVNLALKKKALLNTSLIKYLLKAALAGVYVGIGLILSYRLAEGYFDIHSPTATIMASIFFGVALVLIIYGGAELFTGNTMYFTMSTLRKQTTVKDTLQNWLACYSGNLIGGIFFALLIVGTGLYASAEDSHYLMKTAAAKMDLSIWALFFRGILCNLIVCLAVWIPMHIKGDGAKILVTMLLVFGFVASGFEHSVANMVTFSLALTAPHPETITFLGAIYNLIPVTIGNIVGGGFFLGGVYAYLASPDKQYKQSNRVAGERKLG
>NZ_CP017762.1|WP_050350729.1|2185755_2186319_-|HAD-IA-family-hydrolase
MHLLWDFDGTLINTYPSYTKCFKQVLTKTATENEIYRQLKKSFSHAIAYFQMTKEQEVEVRRLVDNMKPEEVEPFPGLEGVLQAAEVNVIMTHKDRKNVERILGYHGLTSYFKDMVTSDDQFPRKPDSSSYAYLHNKHQIDVAIGDREIDLLPAKELGIKTCSFQNKQADADFHISNYHAFLDTVKL
>NZ_CP017762.1|WP_050350728.1|2186385_2187348_-|D-2-hydroxyacid-dehydrogenase
MDKRTLVMNMDLKEAHVNRIQQALPNWRIVANKELEEVRDDLKEAEIILHWKKAIEPIVLAENKRLKWVQTWSAGIDNLPLIKLQQHNVLVTSANGVHAYPISETIFALILGLTRKIHTYVRQQQEKKWYHARLKQEIHHKTIGIIGVGAIGLETAKIAKAFGMKVLGVRHSGKPTDYVDQMYKPEQLDQVLSQSDFVVITLPLTDATRNMFTATQFKRMKDSAILINIGRGAIVNEGDLLQALQQNEIAGAGLDVFASEPLPANSPLWEMENVIVTPHTAGSTEHYDERVIDEIFLPNLQHYLKGEIPTVNLVNFEKGY
>NZ_CP017762.1|WP_050350727.1|2187505_2187898_-|SLAP-domain-containing-protein
MQRLIFESAWDRTIDARDRERIKHVFEQANEKDKPLRPFLLLNQAHNHLGDLLITVLIQNGLETDWILHNQTLTYYEANTPIATETFSDKRLAIPSKCSMPWTFIFPKKTMQQEPNFKEGKLRSTSLNEI
>NZ_CP017762.1|WP_072741456.1|2188347_2188974_+|LysE-family-transporter
MNFLGYILLGISLSAPVGPINAAQLNKGMNHGFIHAWLVGLGGMIGDLIFMLLIYFGIAQFLTTPFMKTFLWLFGFFILVYTGIESITGAKKSLHVDHAIRQTSKMKSFRTGFLLAISNPLNIIFWLGIYEAVLAKTSDLYSNYQLLLYSSGIFLGIFLWDVIMAGVATSFRRFFHERVQYFITIGAGLLLIGFGLYFGYEAVLLFTN
>NZ_CP017762.1|WP_050350725.1|2189115_2189874_+|YqcI/YcgG-family-protein
MGVLYDKQWLDQEMDRLPPWTQPLYKTFTDMLVGDNTYPCVPARQGFLENQLRFSFISDPREKRAAEEVATALKTYGRNAREFGDYTSLAVFFQTPKDMYTTYTVEDYRNLFWNIINKVTAYDEKAWPESIPQNPTHHEWEFCFDGEPYFIFCATPAHQKRKSRYFPCFFIAFQPRWVFANLNRNTAFGRKMKNIIRRRLIKYDGMPGHPDLKWYGQEDNHEWKQYFLSDEEDSPSKCPFMRMRQKTSSFFK
>NZ_CP017762.1|WP_050350723.1|2190275_2191229_-|arginine-deiminase
MVQLDKPSCWSEHGALQTVLVCSPSEQSIPSLQVAENVQWSAPVQQKKALENFHTFILTLQQEGIHTIDYSLHLDAVTQRLSEQLINRFFVRDLACVFGNKIFPGVAGSFMRRPEYDQVHDLLDKWFPDAFIKEAKQGLKALEYGDVLILNSDAIFINIGMRTSLESVEQMMENLFQAGFSEIGVISLPRRADTLHLDMNCNVANEDLVVAKSYMRFLPVHLTNAEGIQWYDMAEQFLNRHGFSVYWLEKYETIPDINFLNIDPETILISKQAHKQMLQSHPKLKHKRFLEIDVSELEKAGGGIRCMTLPLLRKRSI

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Crispr_ID: NZ_CP017762_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_3

3353478-3354041

Orphan

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRISPRCasFinder

8 spacers

The CRISPR arrays of NZ_CP017762_3

>merge|NZ_CP017762|3|3353478-3354041|CRT,PILER-CR,CRISPRCasFinder
TCTGAGCTTGTTGTATCTATATAAGGTGCGACGTTTAAACGAGTTAGGTTATTCCGGTCGCCGTTATATTTCAATCCACGCACCTATATAAGGTGCGACGGCTTATTAGGGTGTAGGTTTTGCTTCAGGATGTGATTTCAATCCACGCACCTATATAAGGTGCGACGCTTAGTAAAGGCGTGATAACCAACGAAAAGTGGATTTCAATCCACGCACCTATATAAGGTGCGACCAAGGAAAATTATAAATTGTATCGAGAAGAAATAATTTCAATCCACGCACCTATATAAGGTGCGACTTGTATATATTTAATATCAGTCATCATTTCAGCCCAATTTCAATCCACGCACCTATATAAGGTGCGACCGAGTACACAGAGCAGGAAGTACAAGCGGTATGATTTCAATCCACGCACCTATATAAGGTGCGACTTGAAATAGCTACATCACAAGAAGGGTTTGGGACAATTTCAATCCACGCACCTATATAAGGTGCGACAAAAGGGGAAAGTCAATTGGAAAGAATTAACTATATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|3|3|3353478-3354041|CRT
TCTGAGCTTGTTGTATCTATATAAGGTGCGAC	GTTTAAACGAGTTAGGTTATTCCGGTCGCCGTTAT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GGCTTATTAGGGTGTAGGTTTTGCTTCAGGATGTG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GCTTAGTAAAGGCGTGATAACCAACGAAAAGTGG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CAAGGAAAATTATAAATTGTATCGAGAAGAAATA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTGTATATATTTAATATCAGTCATCATTTCAGCCCA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CGAGTACACAGAGCAGGAAGTACAAGCGGTATG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTGAAATAGCTACATCACAAGAAGGGTTTGGGACA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	AAAAGGGGAAAGTCAATTGGAAAGAATTAACTAT
ATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|3|3|3353545-3354041|PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GGCTTATTAGGGTGTAGGTTTTGCTTCAGGATGTG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GCTTAGTAAAGGCGTGATAACCAACGAAAAGTGG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CAAGGAAAATTATAAATTGTATCGAGAAGAAATA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTGTATATATTTAATATCAGTCATCATTTCAGCCCA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CGAGTACACAGAGCAGGAAGTACAAGCGGTATG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTGAAATAGCTACATCACAAGAAGGGTTTGGGACA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	AAAAGGGGAAAGTCAATTGGAAAGAATTAACTAT
ATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|3|3|3353545-3354041|CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GGCTTATTAGGGTGTAGGTTTTGCTTCAGGATGTG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GCTTAGTAAAGGCGTGATAACCAACGAAAAGTGG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CAAGGAAAATTATAAATTGTATCGAGAAGAAATA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTGTATATATTTAATATCAGTCATCATTTCAGCCCA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CGAGTACACAGAGCAGGAAGTACAAGCGGTATG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTGAAATAGCTACATCACAAGAAGGGTTTGGGACA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	AAAAGGGGAAAGTCAATTGGAAAGAATTAACTAT
ATTTCAATCCACGCACCTATATAAGGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_072741887.1\|3341804_3342884_+\|M24-family-metallopeptidase	unknown	unknown	gnl\|CDD\|223085
NZ_CP017762.1\|WP_072741897.1\|3360083_3360752_+\|fructose-6-phosphate-aldolase	unknown	unknown	gnl\|CDD\|188643
NZ_CP017762.1\|WP_072741900.1\|3364959_3365268_+\|PTS-fructose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99911
NZ_CP017762.1\|WP_050351254.1\|3350873_3351071_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741899.1\|3364495_3364963_+\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|273298
NZ_CP017762.1\|WP_050351259.1\|3344257_3345136_+\|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl\|CDD\|369882
NZ_CP017762.1\|WP_072741890.1\|3349263_3350598_+\|citrate-transporter	unknown	unknown	gnl\|CDD\|225407
NZ_CP017762.1\|WP_072741889.1\|3346707_3348336_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP017762.1\|WP_072741891.1\|3352266_3353397_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379138
NZ_CP017762.1\|WP_083547287.1\|3359536_3359902_+\|PTS-glucitol/sorbitol-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|367683
NZ_CP017762.1\|WP_072741896.1\|3358444_3359443_+\|PTS-glucitol/sorbitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226255
NZ_CP017762.1\|WP_072741892.1\|3354532_3355333_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180439
NZ_CP017762.1\|WP_156875351.1\|3362536_3364489_+\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
NZ_CP017762.1\|WP_050351258.1\|3345930_3346371_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050351256.1\|3348349_3349081_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP017762.1\|WP_072741895.1\|3357883_3358429_+\|PTS-glucitol/sorbitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|367578
NZ_CP017762.1\|WP_050351262.1\|3340433_3341771_+\|sugar-porter-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340917
NZ_CP017762.1\|WP_072741894.1\|3357432_3357858_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|369138
NZ_CP017762.1\|WP_072741893.1\|3355414_3357352_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP017762.1\|WP_072741888.1\|3343402_3344188_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235506

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_072741887.1\|3341804_3342884_+\|M24-family-metallopeptidase	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	1.87248e-14
NZ_CP017762.1\|WP_072741897.1\|3360083_3360752_+\|fructose-6-phosphate-aldolase	gnl\|CDD\|188643	cd00956, Transaldolase_FSA, Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea. Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea, which are member of the MipB/TalC subfamily of class I aldolases. FSA catalyze an aldol cleavage of fructose 6-phosphate and do not utilize fructose, fructose 1-phosphate, fructose 1,6-phosphate, or dihydroxyacetone phosphate. The enzymes belong to the transaldolase family that serves in transfer reactions in the pentose phosphate cycle, and are more distantly related to fructose 1,6-bisphosphate aldolase.	1.25477e-73
NZ_CP017762.1\|WP_072741888.1\|3343402_3344188_+\|SDR-family-oxidoreductase	gnl\|CDD\|235506	PRK05565, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	4.39588e-86
NZ_CP017762.1\|WP_072741899.1\|3364495_3364963_+\|PTS-transporter-subunit-EIIA	gnl\|CDD\|273298	TIGR00848, Includes:_Phosphotransferase_enzyme_IIA_component, PTS system, fructose subfamily, IIA component. 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	2.74779e-41
NZ_CP017762.1\|WP_050351259.1\|3344257_3345136_+\|SMP-30/gluconolactonase/LRE-family-protein	gnl\|CDD\|369882	pfam08450, SGL, SMP-30/Gluconolaconase/LRE-like region. This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyze diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.	1.10717e-88
NZ_CP017762.1\|WP_072741890.1\|3349263_3350598_+\|citrate-transporter	gnl\|CDD\|225407	COG2851, CitM, H+/citrate symporter [Energy production and conversion].	4.17809e-167
NZ_CP017762.1\|WP_072741889.1\|3346707_3348336_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	2.90748e-172
NZ_CP017762.1\|WP_072741891.1\|3352266_3353397_-\|hypothetical-protein	gnl\|CDD\|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.25464e-12
NZ_CP017762.1\|WP_083547287.1\|3359536_3359902_+\|PTS-glucitol/sorbitol-transporter-subunit-IIA	gnl\|CDD\|367683	pfam03829, PTSIIA_gutA, PTS system glucitol/sorbitol-specific IIA component.	3.14499e-51
NZ_CP017762.1\|WP_072741896.1\|3358444_3359443_+\|PTS-glucitol/sorbitol-transporter-subunit-IIB	gnl\|CDD\|226255	COG3732, SrlE, Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism].	3.77904e-167
NZ_CP017762.1\|WP_072741892.1\|3354532_3355333_+\|SDR-family-oxidoreductase	gnl\|CDD\|180439	PRK06171, PRK06171, sorbitol-6-phosphate 2-dehydrogenase; Provisional.	1.08979e-143
NZ_CP017762.1\|WP_156875351.1\|3362536_3364489_+\|PRD-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.33823e-38
NZ_CP017762.1\|WP_072741894.1\|3357432_3357858_+\|transcriptional-regulator	gnl\|CDD\|369138	pfam06923, GutM, Glucitol operon activator protein (GutM). This family consists of several glucitol operon activator (GutM) proteins. Expression of the glucitol (gut) operon in Escherichia coli is regulated by an unusual, complex system which consists of an activator (encoded by the gutM gene) and a repressor (encoded by the gutR gene) in addition to the cAMP-CRP complex (CRP, cAMP receptor protein). Synthesis of the mRNA, which initiates at the promoter specific to the gutR gene, occurs within the gutM gene. Expressional control of the gut operon appears to occur as a consequence of the antagonistic action of the products of the autogenously regulated gutM and gutR genes.	4.08396e-39
NZ_CP017762.1\|WP_072741895.1\|3357883_3358429_+\|PTS-glucitol/sorbitol-transporter-subunit-IIC	gnl\|CDD\|367578	pfam03608, EII-GUT, PTS system enzyme II sorbitol-specific factor.	1.05522e-94
NZ_CP017762.1\|WP_050351262.1\|3340433_3341771_+\|sugar-porter-family-MFS-transporter	gnl\|CDD\|340917	cd17359, MFS_XylE_like, D-xylose-proton symporter and similar transporters of the Major Facilitator Superfamily. This subfamily includes bacterial transporters such as D-xylose-proton symporter (XylE or XylT), arabinose-proton symporter (AraE), galactose-proton symporter (GalP), major myo-inositol transporter IolT, glucose transport protein, putative metabolite transport proteins YfiG, YncC, and YwtG, and similar proteins. The symporters XylE, AraE, and GalP facilitate the uptake of D-xylose, arabinose, and galactose, respectively, across the boundary membrane with the concomitant transport of protons into the cell. IolT is involved in polyol metabolism and myo-inositol degradation into acetyl-CoA. The XylE-like subfamily belongs to the Glucose transporter -like (GLUT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74405e-151
NZ_CP017762.1\|WP_050351256.1\|3348349_3349081_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.24412e-79
NZ_CP017762.1\|WP_072741900.1\|3364959_3365268_+\|PTS-fructose-transporter-subunit-IIB	gnl\|CDD\|99911	cd05569, PTS_IIB_fructose, PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and FruB) each containing 3 domains. The FruA protein contains two tandem nonidentical IIB domains and a C-terminal IIC transmembrane domain. Both IIB domains of FruA are included in this alignment. The FruB protein (also referred to as diphosphoryl transfer protein) contains a IIA domain, a domain of unknown function, and an Hpr-like domain called FPr (fructose-inducible HPr). This familiy also includes the IIB domains of several fructose-like PTS permeases including the Frv permease encoded by the frvABXR operon, the Frw permease encoded by the frwACBD operon, the Frx permease encoded by the hrsA gene, and the Fry permease encoded by the fryABC (ypdDGH) operon. FruAB takes up exogenous fructose, releasing the 1-phosphate ester in to the cytoplasm in preparation for metabolism primarily via glycolysis. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include fructose, chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, and a sensory system with similarity to the bacterial bgl system.	5.87749e-40
NZ_CP017762.1\|WP_072741893.1\|3355414_3357352_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	7.20558e-27

>NZ_CP017762.1|WP_072741891.1|3352266_3353397_-|hypothetical-protein
MFIYILISLSIIILTVIISVLWLISWSKKPDADYVLKFIAKNPQRSSLIIIKNGKSLANVNANERKPLASTVKIMIAIEFSQQAANGSINPDEKVHLDDLARFYVSHTDGGAHEKWLIEMEKHGFLQDRSVSLMNIAKGMMSHSSNANTEYLMMRLGLENINKNVNKLELPQHEKLFPFVSALFIPYEVALNKGLDITNKQDTKKILAHIQEMSQEAYINEAIKIHQKLSQDVNGEYKECVNIREWYNSEFDKINSKRFTHSTTSEYISILEQMNRGSYFPSHVWAYLQPIIEWPMKFENNQARFKHVGGKGGSTASILTYAFYAEDKEGNKMELAAFFNDIEGYETMKLSNSSSAFQLAMFTEGAKWKKKLQQLH
>NZ_CP017762.1|WP_050351254.1|3350873_3351071_-|hypothetical-protein
MLMGVTNGMVVFYSLIFHPIAVGLYNANVYPTSDSITGYIFKYVAIFSSGLNYHARMTLGRMPLW
>NZ_CP017762.1|WP_072741890.1|3349263_3350598_+|citrate-transporter
MGFLSIIGFLTIIIIVLLLLSGRVAPIIALVLTPIIGALIAGFELKEIGTFFDDGITDVVHVAIMFIFAILFFGIMQDVGLFDPLIRGMINISQGNIIAISVGSVLIAAIAQLDGSGASTFLITIPALLPLYKKLKMNPYLLLLLIAGSASIMNMLPWAGPLGRSVSVLNMDVTELWRPLIPIQVIGLMLMVVLAIVLGYREKKRIMKVYGSIEAASAMEPDVPSVGGSSESINQASESAAWKFWLNVLLTIAVVGTLVWGIIPAGLVFMIGVSLALPLNYPNMEDQMDRIFAHAPNALMMATIILAAGTFLGILTGTGMLDAIAKDVVKVIPAFIAPYIHLIIGFFGVPFDLLLSTDAYYFALMPVVEQIATGFGIDSLSTGYAMIVGNIVGTFISPFSPAVWLALGLAGLEMGRHIRYSLFWLWGLSIVLLASTVAIGLITV
>NZ_CP017762.1|WP_050351256.1|3348349_3349081_+|response-regulator
MRKQIHVLIIEDDFRVAAINKQFVEQIDGYRVVKSVKTGKEAYQYLQMTEVDLILLDIYIPDVEGLDLFWNLRSKYKAVDIVIVSAAAEANIVEDVLRGGIFDYIIKPVDANRFAEMLRRYQERRRFLATKEILNQQEIDDVIQKNTSNFPNAKKRNSELPKGIDPITLQEVTNLLEDKQVKGITAVDLSEQIGTSRSTARRYLEYLVSLKKIKTTLLYGNVGRPERLYVLRETYEQNVTNKN
>NZ_CP017762.1|WP_072741889.1|3346707_3348336_+|sensor-histidine-kinase
MLVIHKWQQRWRVKQNFSLKVKMICLISILIIGVFIIFGLFLRSFISTIMEDQIAKRALSVAQSVANMPSVQEAFERKHPETVIQDIVKPIQRNIGAEFIVVGNREEIRYSHPEVDKIGKKMVGGDNNRALEKGEAYISKRKGSLGLSIRGKAPIKNQDGAIIGVVSVGFLNEEVQSIIQKQSRSLWLTLLGIILLGVIGAIVIATYLKKLLSGMEPEEITQLLLQKEAILQSTHEGIIAVDNQGRMIIMNTAAQNILLKQEVESSQYMGRSVRDFLPHTGLFHVLETGEKHYNKEMILGDTVVLANRTPIFHQQSIIGAVTTFREKTELESITKELSQIKQYANAQRAQTHEFSNKLYTILGLLQLGKQEEAISFIKQENKIQGTFSQFLLENITDPMIQGLLQGKLNQANELGITMSIHPNSQLIACFSGEKQRAFLTAVGNLLENAIESVKHEVKPKREIAILLTDIGNDVIVEVDDSGEGLSSQDLDHIFEQGYTKKEGEHRGVGLALSKHLLNRVGGDILVEGGELGGARFIIIIPK
>NZ_CP017762.1|WP_050351258.1|3345930_3346371_-|hypothetical-protein
MWLEVSNLNSQLIHLNQLISSSNIRLQEKREELRRLNETLTKLQQNKNDFLKKKDTCIQPEFTTKNFHGKLANEVQSFRENQLQISFLAIPRKYLKKAKNIIMDQIRKIEQEIAAIESNITSWKREHAMVTKQKREVENQIGVDFR
>NZ_CP017762.1|WP_050351259.1|3344257_3345136_+|SMP-30/gluconolactonase/LRE-family-protein
MKAKLEKLYKGQLSEGPIWDNEKNRLLFVDILNNRLNIYSPDSQTLHHIEFPTNVTSVAKINNSELLLTTRNKVILYDENQKEIRDFLTLPIPTDTIRFNDGKCDPYNRFWVGTMSETGETGKANLYVIDAHGNITKAKEGVTISNGMAWNQSADTMYFIDTPTKKVMAYPFSMETSKLVNGRVIIDLNTIDGAPDGMTIDKNDRLWIALWGGSQVICVDPKLGEIVESISLPVSNVTSCAFGGKDLQTLYITTAREGVPHDRIDVEKQAGSLFAYKLPIAGTKSNLYKYEI
>NZ_CP017762.1|WP_072741888.1|3343402_3344188_+|SDR-family-oxidoreductase
MSTMDGQVVIVTGAGKGIGKGIAKLFSQKGASVVIATRGEEEGLQTEQEIIDSGGEACFIQTDVSIEADIIEMVDKTLDRYGKINTLINNAGITVFKTIEEMTVDDWEEIINIDLRGTFLCSKYVIPAMKDEGKGSIINISSNHALSTLPNTEVYAAAKGGVNAMTRSMALSLGSYNIRVNAICPGFTDTPHYRNWLQASNQPEQTENEVLALHATNRISSPEDIAKLSLYLASDDSTMMTGECLVIDGGLSVRLYHAATF
>NZ_CP017762.1|WP_072741887.1|3341804_3342884_+|M24-family-metallopeptidase
MTKLNHSKLLSLMEQENLDGILLARRDSFSWFTSGSYNYVLLSTEIGIAYLYITRKNIICITSEIEKDRLLEEELFQEDMDIVTCPWYKDIDTFASSFFKGKIGSDDGRVGTIHVLPQLKALRAGLSEDEITHYHSFGQKSAEIVENVCRICMPGMTEHEISGMVANRCITEGIEPVCLLVAADERIDRYKHPIPTQNKLKHVLMIVLGAQYRGLNISLTRFVQFGKMDKSKYDKVNSLANIHAQIIHSTVQGVPYKTIFENAITAYKMEGYEHDWKLHHQGGPTGYSCREEIISLDSEGIVLKNQAFAFNPSLKGIKSEDTFVVKEEGCLLLTRTASWPIITCVVEGKEYAMADVLIR
>NZ_CP017762.1|WP_050351262.1|3340433_3341771_+|sugar-porter-family-MFS-transporter
MINKKLIYILGALGGLLYGYDLGVISGALLFIKNDIPLTSFTEGLVVSSLLFGAIFGSGFSGPLSDRLGRRKLIFIISIIFTIGTLVATFSQSVEMLVAGRLILGFAVGGSSAIVPVYLSEMAPTHERGSLSSLNQLMITIGILLSYLINYAFTGIEGWRWMIGLGVIPSIILMIGVTFMPESPRWLLKYHGEEAARRVMKITRTKEEIEEEIHEMIEIDRLSEGTWKVLSSSWLRPILIIGCIFAMFQQIIGTNAIIYYAPTIFTEAGLGNSTAILSTVGIGSINVIVTIVAIMIIDKVNRKKLLLIGNIGMVSSLIIMSAFIHMVGLASSAWIIVGCLTTFIIFFAFTWGPVVWVMLPELFPMRARGAATGIATLCLSLGSLLVAQFFPMLTEVISIKFVFLIFAAIGVMAMLFVIKYLPETRGRSLEEIEVELRKRTKTKNA
>NZ_CP017762.1|WP_072741892.1|3354532_3355333_+|SDR-family-oxidoreductase
MNQNWLDLDGKVAIVTGGASGIGFQIVNELLNNGAKVVVADLHGEEGEQENQSYFIPCDVSNKKMVIDTVGKTVELFGKVDILINNAGVNLPRLLVDDRKEKPEYELTEDEFDLMVGVNQKGTYLFSQAAAKQMLKQKKGVIINVASEAGQEGSAGQSCYSATKGAVISFTRAWAKELGKFNIRVVGLAPGVIEATGLRTDAYNEALAYTRNVKVNELSTDYSKSIPLGREGKLTEIAHLAAFLASDKSSYITGTTVNISGGKSRG
>NZ_CP017762.1|WP_072741893.1|3355414_3357352_+|BglG-family-transcription-antiterminator
MSDFILAENSARLLSIIRKRDYTSLLFLAESMEVSTRTIQNYIRQINQELKGMAKVENVRGKGYRLSIIDKYKFEHLLEKIEQNHTLIDSSKRRIGLIIDLLINGEKSYTLDEMAFELNLGRTTLVTELRKASMSLATYNLKIFGKPNTGMQLSYEEMDLRFFIIENIFDILYGAYPLDCDVVENIANVANRYDLESNTKKKLLEFIVVMLDRLSKNHALKYVKKDHYSLIHQHDLNIAKDISSIIERSLPIKIPEEEVLFISIPIAGRRTPTNNRTMTAIQVTDEVKNLLNKIVEEIGFKQEAIEQNEAFFVDLQYHLTFMLNRLMFGLRINNPMLKDIRDRFPVAFKMAKVAGQVISREYSIAVSDEELAYLAFYFEVFISQSDSKVNRFKRAAVICGTGRGTARIIKIQLEEVLHPATQLDIFSEIDVRREGLNSYDIIFTTVHLSIKVDKPVVQINEIFDAHHLKKKVEEIAYMQSFNLEAADGGNSLLYHLITEDRFFVLDSSISYEANLNYMVEDLIQKGYLDNGFKNRLQARAEKGSMVFDQFIALPHTLNNNSDQLEVALGVLPNKIKADNKEVKLIFLLGLPNLKAQLEDYEQQLVNVYDEIVRISNDRQLVDKISQSTNYEKAIQFLKHVSRFNV
>NZ_CP017762.1|WP_072741894.1|3357432_3357858_+|transcriptional-regulator
MFWYLIILIGVAWLAQSIFGFLQIRHFNRNYAELRALGRVAIGKRTGLFRAGTVVMFCIDKQDRILMAKRMQGVTVMSRVKDLTGFTGKKLLQMKESDYKHVNKLTKIAIQDAINSYDILSKGGELQVKKGWLERLFSKKK
>NZ_CP017762.1|WP_072741895.1|3357883_3358429_+|PTS-glucitol/sorbitol-transporter-subunit-IIC
MDIIITGAEKFMDFFRHGGDVFVGLITDIVPLLIMLLVAMNSLVRLVGEERVEKLAKKSGKNPFTRYFVLPVIGTFVLANPMTLSLGRFLPEKHKPSYYAAASFSCHTHNGLFPHVNPGELFVFLGVAAGITTLGFDTAELALRYFLVGIVTNFFRGWITDYMTSYVSKQQNVKLKQTVEL
>NZ_CP017762.1|WP_072741896.1|3358444_3359443_+|PTS-glucitol/sorbitol-transporter-subunit-IIB
MSKYQSIKITRGSNGFGGPLWITPTEQKNKVVYITGGEKPDIADRIAELTGCELVNGFKTTVPESEIACVIIDCGGTLRCGLYPQKRIPTINIMSTGKSGPLAKHITEDIYVSGVKKGNIQLAEEENEQQEMETSQAAKKQYNYTADKKISEQQKPKGLMAKIGITMGNIVTVFYQAGRDAIDTVIKTILPFMAFVSMLIGVIIESGIGDLFAKFLSPFAGSIWGLIVIALICSFPLLSPFLGPGAVIAQVIGTLIGVEIGKGNIPPNLALPALFAINSQASADFVPVGLGLAEAEPETVEVGVPSVLYGRFLTGAPTVFIAWLASFGLYDG
>NZ_CP017762.1|WP_083547287.1|3359536_3359902_+|PTS-glucitol/sorbitol-transporter-subunit-IIA
MILKYETTVDRVGAHAATFLEEKMLILFGKDAPAELEDYCLSIVINDLKESINVGDILQLNDREYRITAVGEAVEKNLATLGHITLNFDGSQIPELPGTLYLEDRPISEVDIGDEIKIYER
>NZ_CP017762.1|WP_072741897.1|3360083_3360752_+|fructose-6-phosphate-aldolase
MKLFIDSANVEQIKKINNDYPVDGVTTNPSLIAKENRSLFPLINEIRNIIGETKLLFVQTISVDSDSIVNEALQIWENLNRNVIIKIPVTVEGIRAIGILKKHGVKTLATTVYTPMNAYIAAKAGANFVAPYVNRIENLNGNGTQVIKEIRQIFSNAKFSSEIISASFKNVQQIKAVSLSGSDGITVNPQLIEKFLQVPSIKEDVQQFNLDWETVRDEVDSN
>NZ_CP017762.1|WP_156875351.1|3362536_3364489_+|PRD-domain-containing-protein
MQKILTCFLNADGYLTSSYLAKQVGCSAKTVREDIKKLNSELSNICMVILPKRGSGYKLIGENKDELTKRFIHDTNVVISKALQNPVTPEERMRFIVKKLLYTNNCVTISDFATELYVSESTIKNDIKHAKEILNKYNIKIRKGVTGLYAVGHEINKRFCIADFLYQNSKIDEQVIINYMYIENEATNKIIKDIKKTILDILTEENMTISDYTLKKITIHIVIAINRIKNGQYIEFNSERLHQLTNEQEFKTAEKIIASISQKYKMYFFSPEEIAYITMHLIGNRIAKKNQIASNLHELISDEMLKLSLSVIEEVNNNLKGLDLLKDEELIYSLGIHLKQLLNRLDFQMNISNPFLNTVKIKYPLAFEAGVTAAKRIMKETNFKIGDNEIGFLAMHFGAAIEKQKYQQLVKRKKIALVCASGTATSNLLLTKLSHVLEPGYRMMGVYSFHQIEELLAQKPDLILTTVPLLQKINIPVISISNILGEEDILILREDLDKYHRGEKSLVHLMKKNLFFNDVNMNNKKELLHYLTNKMIDAGYITHKIKDSIFLRESIASTAIGNKVAIPHPINIEVSKSCICTAILNNEMDWDKDEKVVIVFIIVLENKWAPYFQEIFSELYSLTSSYDSIGDLQTKNNFDDFIKDITAKLG
>NZ_CP017762.1|WP_072741899.1|3364495_3364963_+|PTS-transporter-subunit-EIIA
MKNIELINEKLIGMESNATTKEEALYEVATIAYKAERVTNKELYYKSLVDRERESTTGFGNGFAIPHAKEDIVKQPTIIVVRLNNAVNWNSLDNKPVKMLVALAIPKKYKGTMHLKLLANLSENLMEEEFRKQLLYSTNKDGICTTIKNIMEELT
>NZ_CP017762.1|WP_072741900.1|3364959_3365268_+|PTS-fructose-transporter-subunit-IIB
MNILAVTACPAGVAHTYMAKRALEKAAKEKGYKIKVETQGSMGIENELKEKEINKADVIIIAADTKIEKANRFMEKNVYETSVSSAVKNASKVIDSATEELA

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Crispr_ID: NZ_CP017762_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_4

3361531-3362032

Orphan

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCTATATAAGGTGCGAC	PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRT

7 spacers

The CRISPR arrays of NZ_CP017762_4

>merge|NZ_CP017762|4|3361531-3362032|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATCCACGCACCTATATAAGGTGCGACAAAACACTCTCTGACTTATACGGGATTTGCCGGAATTTCAATCCACGCACCTATATAAATAAGGTGCGACGGCGATAAAATAACACTTGATAACTTTAACAAGATTTCAATCCACGCACCTATATAAGGTGCGACGTCATTCCGTTTCCTCCTTATAGATAACTAAATACTGAATTTCAATCCACGCACCTATATAAGGTGCGACTGCTGAATATGAATACGGCGGTAATGGATGGTAGTATTTCAATCCACGCACCTATATAAGGTGCGACGATAGACAATGTTTTTTACAAATATGGTGAGGTATTTCAATCCACGCACCTATATAAGGTGCGACGATAGACAATGTTTTTTACAAATATGGTGAGGTATTTCAATCCACGCACCTATATAAGGTGCGACTTAAGTCATACACGAAGCCAAATCAAAAAACAAATAATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|4|4|3361531-3362032|PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	AAAACACTCTCTGACTTATACGGGATTTGCCGGA
ATTTCAATCCACGCACCTATATAAATAAGGTG	CGACGGCGATAAAATAACACTTGATAACTTTAACAAGATTTCAAT
CCACGCACCTATATAAGGTGCGACGTCATTCC	GTTTCCTCCTTATAGATAACTAAATACTGAATTTCAAT
CCACGCACCTATATAAGGTGCGACTGCTGAAT	ATGAATACGGCGGTAATGGATGGTAGTATTTCAAT
CCACGCACCTATATAAGGTGCGACGATAGACA	ATGTTTTTTACAAATATGGTGAGGTATTTCAAT
CCACGCACCTATATAAGGTGCGACGATAGACA	ATGTTTTTTACAAATATGGTGAGGTATTTCAAT
CCACGCACCTATATAAGGTGCGACTTAAGTCA	TACACGAAGCCAAATCAAAAAACAAATAATTTCAAT
CCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|4|4|3361531-3362032|CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGAC	AAAACACTCTCTGACTTATACGGGATTTGCCGGA
ATTTCAATCCACGCACCTATATAAATAAGGTG	CGACGGCGATAAAATAACACTTGATAACTTTAACAAG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GTCATTCCGTTTCCTCCTTATAGATAACTAAATACTGA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TGCTGAATATGAATACGGCGGTAATGGATGGTAGT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GATAGACAATGTTTTTTACAAATATGGTGAGGT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GATAGACAATGTTTTTTACAAATATGGTGAGGT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTAAGTCATACACGAAGCCAAATCAAAAAACAAATA
ATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|4|4|3361531-3362032|CRT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	AAAACACTCTCTGACTTATACGGGATTTGCCGGA
ATTTCAATCCACGCACCTATATAAATAAGGTG	CGACGGCGATAAAATAACACTTGATAACTTTAACAAG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GTCATTCCGTTTCCTCCTTATAGATAACTAAATACTGA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TGCTGAATATGAATACGGCGGTAATGGATGGTAGT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GATAGACAATGTTTTTTACAAATATGGTGAGGT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GATAGACAATGTTTTTTACAAATATGGTGAGGT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TTAAGTCATACACGAAGCCAAATCAAAAAACAAATA
ATTTCAATCCACGCACCTATATAAGGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_072741903.1\|3369386_3370712_+\|6-phospho-alpha-glucosidase	unknown	unknown	gnl\|CDD\|133434
NZ_CP017762.1\|WP_050351244.1\|3371663_3373067_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273920
NZ_CP017762.1\|WP_072741901.1\|3365283_3366294_+\|PTS-fructose-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224218
NZ_CP017762.1\|WP_072740903.1\|3373561_3374950_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NZ_CP017762.1\|WP_072741893.1\|3355414_3357352_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP017762.1\|WP_050351247.1\|3368508_3369228_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP017762.1\|WP_072741890.1\|3349263_3350598_+\|citrate-transporter	unknown	unknown	gnl\|CDD\|225407
NZ_CP017762.1\|WP_072741891.1\|3352266_3353397_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379138
NZ_CP017762.1\|WP_083547287.1\|3359536_3359902_+\|PTS-glucitol/sorbitol-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|367683
NZ_CP017762.1\|WP_050351245.1\|3370915_3371659_+\|chitin-disaccharide-deacetylase	unknown	unknown	gnl\|CDD\|212114
NZ_CP017762.1\|WP_072741896.1\|3358444_3359443_+\|PTS-glucitol/sorbitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226255
NZ_CP017762.1\|WP_072741892.1\|3354532_3355333_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180439
NZ_CP017762.1\|WP_072741902.1\|3366315_3367500_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|224090
NZ_CP017762.1\|WP_156875351.1\|3362536_3364489_+\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
NZ_CP017762.1\|WP_072741894.1\|3357432_3357858_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|369138
NZ_CP017762.1\|WP_072741897.1\|3360083_3360752_+\|fructose-6-phosphate-aldolase	unknown	unknown	gnl\|CDD\|188643
NZ_CP017762.1\|WP_050351254.1\|3350873_3351071_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741895.1\|3357883_3358429_+\|PTS-glucitol/sorbitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|367578
NZ_CP017762.1\|WP_072741900.1\|3364959_3365268_+\|PTS-fructose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99911
NZ_CP017762.1\|WP_072741899.1\|3364495_3364963_+\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|273298

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_072741903.1\|3369386_3370712_+\|6-phospho-alpha-glucosidase	gnl\|CDD\|133434	cd05298, GH4_GlvA_pagL_like, Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases. Bacillus subtilis GlvA and Clostridium acetobutylicum pagL are 6-phospho-alpha-glucosidase, catalyzing the hydrolysis of alpha-glucopyranoside bonds to release glucose from oligosaccharides. The substrate specificities of other members of this subgroup are unknown. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP_PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases, which include 6-phospho-beta-glucosidases, 6-phospho-alpha-glucosidases, alpha-glucosidases/alpha-glucuronidases (only from Thermotoga), and alpha-galactosidases. Members of this subfamily are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP017762.1\|WP_050351244.1\|3371663_3373067_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273920	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.22629e-121
NZ_CP017762.1\|WP_072741901.1\|3365283_3366294_+\|PTS-fructose-transporter-subunit-IIC	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	6.49939e-81
NZ_CP017762.1\|WP_072740903.1\|3373561_3374950_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.29345e-176
NZ_CP017762.1\|WP_072741893.1\|3355414_3357352_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	7.20558e-27
NZ_CP017762.1\|WP_072741890.1\|3349263_3350598_+\|citrate-transporter	gnl\|CDD\|225407	COG2851, CitM, H+/citrate symporter [Energy production and conversion].	4.17809e-167
NZ_CP017762.1\|WP_072741891.1\|3352266_3353397_-\|hypothetical-protein	gnl\|CDD\|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.25464e-12
NZ_CP017762.1\|WP_083547287.1\|3359536_3359902_+\|PTS-glucitol/sorbitol-transporter-subunit-IIA	gnl\|CDD\|367683	pfam03829, PTSIIA_gutA, PTS system glucitol/sorbitol-specific IIA component.	3.14499e-51
NZ_CP017762.1\|WP_050351245.1\|3370915_3371659_+\|chitin-disaccharide-deacetylase	gnl\|CDD\|212114	cd10803, YdjC_EF3048_like, Enterococcus faecalis EF3048 and similar proteins. This subfamily is represented by a putative cellobiose-phosphate cleavage protein EF3048 from Enterococcus faecalis v583. It is similar to Escherichia coli YdjC, a hypothetical protein encoded by the celG gene. EF3048 might function as a homodimer. Each of the monomers consists of a (beta/alpha)-barrel fold that forms an active homodimer. The molecular function of the EF3048 is unclear.	1.87104e-113
NZ_CP017762.1\|WP_072741896.1\|3358444_3359443_+\|PTS-glucitol/sorbitol-transporter-subunit-IIB	gnl\|CDD\|226255	COG3732, SrlE, Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism].	3.77904e-167
NZ_CP017762.1\|WP_072741892.1\|3354532_3355333_+\|SDR-family-oxidoreductase	gnl\|CDD\|180439	PRK06171, PRK06171, sorbitol-6-phosphate 2-dehydrogenase; Provisional.	1.08979e-143
NZ_CP017762.1\|WP_072741902.1\|3366315_3367500_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	9.29788e-151
NZ_CP017762.1\|WP_156875351.1\|3362536_3364489_+\|PRD-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.33823e-38
NZ_CP017762.1\|WP_072741894.1\|3357432_3357858_+\|transcriptional-regulator	gnl\|CDD\|369138	pfam06923, GutM, Glucitol operon activator protein (GutM). This family consists of several glucitol operon activator (GutM) proteins. Expression of the glucitol (gut) operon in Escherichia coli is regulated by an unusual, complex system which consists of an activator (encoded by the gutM gene) and a repressor (encoded by the gutR gene) in addition to the cAMP-CRP complex (CRP, cAMP receptor protein). Synthesis of the mRNA, which initiates at the promoter specific to the gutR gene, occurs within the gutM gene. Expressional control of the gut operon appears to occur as a consequence of the antagonistic action of the products of the autogenously regulated gutM and gutR genes.	4.08396e-39
NZ_CP017762.1\|WP_072741897.1\|3360083_3360752_+\|fructose-6-phosphate-aldolase	gnl\|CDD\|188643	cd00956, Transaldolase_FSA, Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea. Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea, which are member of the MipB/TalC subfamily of class I aldolases. FSA catalyze an aldol cleavage of fructose 6-phosphate and do not utilize fructose, fructose 1-phosphate, fructose 1,6-phosphate, or dihydroxyacetone phosphate. The enzymes belong to the transaldolase family that serves in transfer reactions in the pentose phosphate cycle, and are more distantly related to fructose 1,6-bisphosphate aldolase.	1.25477e-73
NZ_CP017762.1\|WP_050351247.1\|3368508_3369228_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.88724e-73
NZ_CP017762.1\|WP_072741895.1\|3357883_3358429_+\|PTS-glucitol/sorbitol-transporter-subunit-IIC	gnl\|CDD\|367578	pfam03608, EII-GUT, PTS system enzyme II sorbitol-specific factor.	1.05522e-94
NZ_CP017762.1\|WP_072741900.1\|3364959_3365268_+\|PTS-fructose-transporter-subunit-IIB	gnl\|CDD\|99911	cd05569, PTS_IIB_fructose, PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and FruB) each containing 3 domains. The FruA protein contains two tandem nonidentical IIB domains and a C-terminal IIC transmembrane domain. Both IIB domains of FruA are included in this alignment. The FruB protein (also referred to as diphosphoryl transfer protein) contains a IIA domain, a domain of unknown function, and an Hpr-like domain called FPr (fructose-inducible HPr). This familiy also includes the IIB domains of several fructose-like PTS permeases including the Frv permease encoded by the frvABXR operon, the Frw permease encoded by the frwACBD operon, the Frx permease encoded by the hrsA gene, and the Fry permease encoded by the fryABC (ypdDGH) operon. FruAB takes up exogenous fructose, releasing the 1-phosphate ester in to the cytoplasm in preparation for metabolism primarily via glycolysis. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include fructose, chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, and a sensory system with similarity to the bacterial bgl system.	5.87749e-40
NZ_CP017762.1\|WP_072741899.1\|3364495_3364963_+\|PTS-transporter-subunit-EIIA	gnl\|CDD\|273298	TIGR00848, Includes:_Phosphotransferase_enzyme_IIA_component, PTS system, fructose subfamily, IIA component. 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	2.74779e-41

>NZ_CP017762.1|WP_072741897.1|3360083_3360752_+|fructose-6-phosphate-aldolase
MKLFIDSANVEQIKKINNDYPVDGVTTNPSLIAKENRSLFPLINEIRNIIGETKLLFVQTISVDSDSIVNEALQIWENLNRNVIIKIPVTVEGIRAIGILKKHGVKTLATTVYTPMNAYIAAKAGANFVAPYVNRIENLNGNGTQVIKEIRQIFSNAKFSSEIISASFKNVQQIKAVSLSGSDGITVNPQLIEKFLQVPSIKEDVQQFNLDWETVRDEVDSN
>NZ_CP017762.1|WP_083547287.1|3359536_3359902_+|PTS-glucitol/sorbitol-transporter-subunit-IIA
MILKYETTVDRVGAHAATFLEEKMLILFGKDAPAELEDYCLSIVINDLKESINVGDILQLNDREYRITAVGEAVEKNLATLGHITLNFDGSQIPELPGTLYLEDRPISEVDIGDEIKIYER
>NZ_CP017762.1|WP_072741896.1|3358444_3359443_+|PTS-glucitol/sorbitol-transporter-subunit-IIB
MSKYQSIKITRGSNGFGGPLWITPTEQKNKVVYITGGEKPDIADRIAELTGCELVNGFKTTVPESEIACVIIDCGGTLRCGLYPQKRIPTINIMSTGKSGPLAKHITEDIYVSGVKKGNIQLAEEENEQQEMETSQAAKKQYNYTADKKISEQQKPKGLMAKIGITMGNIVTVFYQAGRDAIDTVIKTILPFMAFVSMLIGVIIESGIGDLFAKFLSPFAGSIWGLIVIALICSFPLLSPFLGPGAVIAQVIGTLIGVEIGKGNIPPNLALPALFAINSQASADFVPVGLGLAEAEPETVEVGVPSVLYGRFLTGAPTVFIAWLASFGLYDG
>NZ_CP017762.1|WP_072741895.1|3357883_3358429_+|PTS-glucitol/sorbitol-transporter-subunit-IIC
MDIIITGAEKFMDFFRHGGDVFVGLITDIVPLLIMLLVAMNSLVRLVGEERVEKLAKKSGKNPFTRYFVLPVIGTFVLANPMTLSLGRFLPEKHKPSYYAAASFSCHTHNGLFPHVNPGELFVFLGVAAGITTLGFDTAELALRYFLVGIVTNFFRGWITDYMTSYVSKQQNVKLKQTVEL
>NZ_CP017762.1|WP_072741894.1|3357432_3357858_+|transcriptional-regulator
MFWYLIILIGVAWLAQSIFGFLQIRHFNRNYAELRALGRVAIGKRTGLFRAGTVVMFCIDKQDRILMAKRMQGVTVMSRVKDLTGFTGKKLLQMKESDYKHVNKLTKIAIQDAINSYDILSKGGELQVKKGWLERLFSKKK
>NZ_CP017762.1|WP_072741893.1|3355414_3357352_+|BglG-family-transcription-antiterminator
MSDFILAENSARLLSIIRKRDYTSLLFLAESMEVSTRTIQNYIRQINQELKGMAKVENVRGKGYRLSIIDKYKFEHLLEKIEQNHTLIDSSKRRIGLIIDLLINGEKSYTLDEMAFELNLGRTTLVTELRKASMSLATYNLKIFGKPNTGMQLSYEEMDLRFFIIENIFDILYGAYPLDCDVVENIANVANRYDLESNTKKKLLEFIVVMLDRLSKNHALKYVKKDHYSLIHQHDLNIAKDISSIIERSLPIKIPEEEVLFISIPIAGRRTPTNNRTMTAIQVTDEVKNLLNKIVEEIGFKQEAIEQNEAFFVDLQYHLTFMLNRLMFGLRINNPMLKDIRDRFPVAFKMAKVAGQVISREYSIAVSDEELAYLAFYFEVFISQSDSKVNRFKRAAVICGTGRGTARIIKIQLEEVLHPATQLDIFSEIDVRREGLNSYDIIFTTVHLSIKVDKPVVQINEIFDAHHLKKKVEEIAYMQSFNLEAADGGNSLLYHLITEDRFFVLDSSISYEANLNYMVEDLIQKGYLDNGFKNRLQARAEKGSMVFDQFIALPHTLNNNSDQLEVALGVLPNKIKADNKEVKLIFLLGLPNLKAQLEDYEQQLVNVYDEIVRISNDRQLVDKISQSTNYEKAIQFLKHVSRFNV
>NZ_CP017762.1|WP_072741892.1|3354532_3355333_+|SDR-family-oxidoreductase
MNQNWLDLDGKVAIVTGGASGIGFQIVNELLNNGAKVVVADLHGEEGEQENQSYFIPCDVSNKKMVIDTVGKTVELFGKVDILINNAGVNLPRLLVDDRKEKPEYELTEDEFDLMVGVNQKGTYLFSQAAAKQMLKQKKGVIINVASEAGQEGSAGQSCYSATKGAVISFTRAWAKELGKFNIRVVGLAPGVIEATGLRTDAYNEALAYTRNVKVNELSTDYSKSIPLGREGKLTEIAHLAAFLASDKSSYITGTTVNISGGKSRG
>NZ_CP017762.1|WP_072741891.1|3352266_3353397_-|hypothetical-protein
MFIYILISLSIIILTVIISVLWLISWSKKPDADYVLKFIAKNPQRSSLIIIKNGKSLANVNANERKPLASTVKIMIAIEFSQQAANGSINPDEKVHLDDLARFYVSHTDGGAHEKWLIEMEKHGFLQDRSVSLMNIAKGMMSHSSNANTEYLMMRLGLENINKNVNKLELPQHEKLFPFVSALFIPYEVALNKGLDITNKQDTKKILAHIQEMSQEAYINEAIKIHQKLSQDVNGEYKECVNIREWYNSEFDKINSKRFTHSTTSEYISILEQMNRGSYFPSHVWAYLQPIIEWPMKFENNQARFKHVGGKGGSTASILTYAFYAEDKEGNKMELAAFFNDIEGYETMKLSNSSSAFQLAMFTEGAKWKKKLQQLH
>NZ_CP017762.1|WP_050351254.1|3350873_3351071_-|hypothetical-protein
MLMGVTNGMVVFYSLIFHPIAVGLYNANVYPTSDSITGYIFKYVAIFSSGLNYHARMTLGRMPLW
>NZ_CP017762.1|WP_072741890.1|3349263_3350598_+|citrate-transporter
MGFLSIIGFLTIIIIVLLLLSGRVAPIIALVLTPIIGALIAGFELKEIGTFFDDGITDVVHVAIMFIFAILFFGIMQDVGLFDPLIRGMINISQGNIIAISVGSVLIAAIAQLDGSGASTFLITIPALLPLYKKLKMNPYLLLLLIAGSASIMNMLPWAGPLGRSVSVLNMDVTELWRPLIPIQVIGLMLMVVLAIVLGYREKKRIMKVYGSIEAASAMEPDVPSVGGSSESINQASESAAWKFWLNVLLTIAVVGTLVWGIIPAGLVFMIGVSLALPLNYPNMEDQMDRIFAHAPNALMMATIILAAGTFLGILTGTGMLDAIAKDVVKVIPAFIAPYIHLIIGFFGVPFDLLLSTDAYYFALMPVVEQIATGFGIDSLSTGYAMIVGNIVGTFISPFSPAVWLALGLAGLEMGRHIRYSLFWLWGLSIVLLASTVAIGLITV
>NZ_CP017762.1|WP_156875351.1|3362536_3364489_+|PRD-domain-containing-protein
MQKILTCFLNADGYLTSSYLAKQVGCSAKTVREDIKKLNSELSNICMVILPKRGSGYKLIGENKDELTKRFIHDTNVVISKALQNPVTPEERMRFIVKKLLYTNNCVTISDFATELYVSESTIKNDIKHAKEILNKYNIKIRKGVTGLYAVGHEINKRFCIADFLYQNSKIDEQVIINYMYIENEATNKIIKDIKKTILDILTEENMTISDYTLKKITIHIVIAINRIKNGQYIEFNSERLHQLTNEQEFKTAEKIIASISQKYKMYFFSPEEIAYITMHLIGNRIAKKNQIASNLHELISDEMLKLSLSVIEEVNNNLKGLDLLKDEELIYSLGIHLKQLLNRLDFQMNISNPFLNTVKIKYPLAFEAGVTAAKRIMKETNFKIGDNEIGFLAMHFGAAIEKQKYQQLVKRKKIALVCASGTATSNLLLTKLSHVLEPGYRMMGVYSFHQIEELLAQKPDLILTTVPLLQKINIPVISISNILGEEDILILREDLDKYHRGEKSLVHLMKKNLFFNDVNMNNKKELLHYLTNKMIDAGYITHKIKDSIFLRESIASTAIGNKVAIPHPINIEVSKSCICTAILNNEMDWDKDEKVVIVFIIVLENKWAPYFQEIFSELYSLTSSYDSIGDLQTKNNFDDFIKDITAKLG
>NZ_CP017762.1|WP_072741899.1|3364495_3364963_+|PTS-transporter-subunit-EIIA
MKNIELINEKLIGMESNATTKEEALYEVATIAYKAERVTNKELYYKSLVDRERESTTGFGNGFAIPHAKEDIVKQPTIIVVRLNNAVNWNSLDNKPVKMLVALAIPKKYKGTMHLKLLANLSENLMEEEFRKQLLYSTNKDGICTTIKNIMEELT
>NZ_CP017762.1|WP_072741900.1|3364959_3365268_+|PTS-fructose-transporter-subunit-IIB
MNILAVTACPAGVAHTYMAKRALEKAAKEKGYKIKVETQGSMGIENELKEKEINKADVIIIAADTKIEKANRFMEKNVYETSVSSAVKNASKVIDSATEELA
>NZ_CP017762.1|WP_072741901.1|3365283_3366294_+|PTS-fructose-transporter-subunit-IIC
MNNVKKHLMTGVSYMIPIVVAGGILLSLGVIIGEETAIGEQLVNYGVWTLGLMVPMIAGYISYSIADRPGVAVGLASGVFASELGTGYIGGILVGFFAGWITNQLKKIPMHHHIAVIKPIMIIPLLGIGASALFMYIISIPLTPAMEGLEKWLVSLEGSNLLFLGFIIAAMMAFDMGGPVNKIALAFAYATLAEGIYAPMAACWIGIMAAPLGLGLSTLIFPKKFSKSEKGNSVPAIIMGSLGITEGAIPYAVATPLKVIPVITLASGIGGGIALVLGAKAPIPAAIGIWGLPFVQKPLMLLVGLLISIVTIALVVGLIRKESDVNEEEEGQLMFE
>NZ_CP017762.1|WP_072741902.1|3366315_3367500_+|pyridoxal-phosphate-dependent-aminotransferase
MKKQFDKVVERRGTYCTQWDYIEDRFGEKNILPFSISDMDFQTPVEIRNRIKEWTDHGVFGYTRWNNSDYKNAIVTWYKKRHDADIVSEWIIYSPSVIYSISQLIALLTRKNDAIVMQTPAYDAFFKTIKQSERKLIKNPLLYEDGYYKIDWIDLEKKLAKSESKVFLLCNPHNPTGRVWRREEIIKIVKLCDCYGVKVISDDIHMDIIYRENKYIPIINVASELNNVFICTSGSKTFNTPSLGGSYVIIPDHKVRSKYLSLMKDRDGLGSAPIFGMVALIEGYNYAEYWVDELRKYLYQNMEIVYDYLKKELPLLHFSIPESTYLAWIDASKLNASNKKIQDYLVHVGKVGIMSGEVYGETEKFLRMNIGCPKEKLYDGLEKLKFSVNHMLNA
>NZ_CP017762.1|WP_050351247.1|3368508_3369228_-|GntR-family-transcriptional-regulator
MWNNSLPLYRQIANKIKEDIIGSKLAKGDAIPAEAKLAKTYEVSRVTVRQAIKLLVEEGLLYSIQGSGTYVAHNKVEHNILHLQGFTEEMQKLQNNPKNEVLEFKLTDPTDEVQEILNISNNEKVYYMKRLRYADHEPFLLEESFLPVDLFPDFSIEVIKKSKYNYIENKGYTIDKRYGELIPILPNEELKKILQLQDNQPLLFLKAFTVFEDGKPFEYSKVYYHPKKYSFKFISEKNH
>NZ_CP017762.1|WP_072741903.1|3369386_3370712_+|6-phospho-alpha-glucosidase
MKKQNLVIVGGGSTYTIGMIMSLIAEKKNFPLNSITFYDNDEKRQEKVAKATSIILDEYYPELESFHYTTDKETAFTGIDIAFIQIRTGGLQMRELDEQIPLKYGVVGQETCGPGGMAYGLRSIRDMIELVYDIKKYSKDAWILNYTNPAAIVAEALKREFPQDPKLLNICDMPIAIMHSFATMLNKNIWDLVPSYFGLNHFGWFTKIEDSEGNDLTQIIKDTIMGEGFVPTDQEIANDQSWQQTFEQARKMLIDFPEFLPNTYLQYYLYPDDLAKKESLTNTRARQVINGREKRITELCNQIIQDKSTKNVELHVDIHGVYMVKAAASLVYNLKQTYIVMVENNGIISNIPDDATVEVPALLTASGPKPFSVGKIPTFYKGLIENQFAYEKLVADAYFENSYTKALQALTLNRTVVHVPTAKAILDDLIEANKGYWPELQ
>NZ_CP017762.1|WP_050351245.1|3370915_3371659_+|chitin-disaccharide-deacetylase
MKKLIINADDFGYSRSVNYGIIDAHTDGVLTSTTLMTNMPGAEHAYQLGEKHKTLGIGVHLTLTCGKPILKNHHTLVDADGNFKKLYHYQKLFHIDTNELYAEWKAQIEAFLDSGLAPTHLDSHHHINNLEPILPVFLELAKEYKLPVRHNFKIKPEFGTLITTDHFEYNPEILLGDVNTIVEEYKEAQTIEIMCHPAYLDKSLMTGSSYATPRIEELAMLIHPDVKKKLQQHFQLMTYRELEKEEA
>NZ_CP017762.1|WP_050351244.1|3371663_3373067_+|PTS-transporter-subunit-EIIC
MRKFMQKLGKSMLIPIVAMPIAGILFRLSAGDLLDWKLFQAAGVIFANMDMLIAIGIAMGLAKTKDRGIPALTGFLAITVLNEGLTLMNPDLDMSVFGGVIAGLIAAGIYNRFKDTKLPSMFSFFGGEKFPITMIILTMIPVAGIFSLIWPYAQQGIDSFAQALVGLGAVGIFIFGFLNRFLLPFGLHHVLNTYIYFGLGSYENASGEVVTGEITRFMNGDPTAGYFLGGFFIVMIFGVPAIALAIARAAHKKKKAETKALMSSGALTSVVAGLTEPIEFTFIFTSPLLYFIHSVYTGLAGATLYLFGVRHGFSWGGSVIDYGLNLSLSDSGLMIIPIGLAFGLLYYFTFYTIIVKKNIKVIGREDDVEFGFQADEKEQSLKLSHNKFEYMAKKILENIGGKENVVDYENCMTRLRLVVKDASLVDEDKIKQTGAHGVVKVDNKHIQIIIGPEAGTVLTEFKKHIEK
>NZ_CP017762.1|WP_072740903.1|3373561_3374950_+|group-II-intron-reverse-transcriptase/maturase
MRQLQKTGESGYRQRDSVEHEGYVEAHSTFHGEQNNQNGVSNLFERILSRNNLNQAYLQVVRNKGAAGIDGMTYDQLLPYLKEHKEELLTQLRQGKYKPQPVLRVEIPKPDGGKRKLGIPTVIDRMLQQAINQVLQPIFEPTFSDNSFGFRPKRSAHHAIIRAKSYYEQGYKYVVDLDMKSYFDTVNHDKLMYFVEKQISDKRVLHLIRRYLLSGIMINGIFEKSEQGTPQGGNLSPLLSNIYLNELDQLLEKRGHRFVRYADDCNIYVKSRRAGYRVMDNITTFLERDLSLTVNREKSAVGSPLKRKFLGFCLLATKNGVKIRPHNKAKVTVQEKLKRITKRNRGRNLEVILKEIQQLMTGWINYYGIGEMKGFMKNLNGWLKRRIRQYIWKQWKNPRTKRKNLIHLGIDKRKAYEWSNTRKGYWTISSSYVLHRSLTDKELASRGYKDIALQYQFVHSNY

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Crispr_ID: NZ_CP017762_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_5

3367804-3368240

Orphan

I-C

Consensus_repeat	Method
AATTTCAATCCACGCACCTATACAAGGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACCTATACAAGGTGCGAC	PILER-CR
ATTTCAATCCACGCACCTATACAAGGTGCGAC	CRT

6 spacers

The CRISPR arrays of NZ_CP017762_5

>merge|NZ_CP017762|5|3367804-3368240|CRISPRCasFinder,PILER-CR,CRT
AATTTCAATCCACGCACCTATACAAGGTGCGACGACAAGTCAAGTCGCCGAGGTAATGCAAATGGATAATTTCAATCCACGCACCTATACAAGGTGCGACCGTAATCTTCTAATGTTAAGTCTGCGCGTTTAAATTTCAATCCACGCACCTATACAAGGTGCGACTCTGGTGGCGGAGGATGTGTTTATTTACCTTGAAGATTTCAATCCACGCACCTATACAAGGTGCGACTAGATTTAGCAAATTACAGCATTATGGCATTGATGATTTCAATCCACGCACCTATACAAGGTGCGACTTGAAATAGAAAGTGAATATTGCCATAAGGGTAAAGAGAATTTCAATCCACGCACCTATACAAGGTGCGACATGGTTCTATTGTTTTGCAAGATAAAGCTTGTGTAATTTCAATCCACGCACCTATACAAGGTGCGAC

>NZ_CP017762|5|5|3367804-3368240|CRISPRCasFinder
AATTTCAATCCACGCACCTATACAAGGTGCGAC	GACAAGTCAAGTCGCCGAGGTAATGCAAATGGAT
AATTTCAATCCACGCACCTATACAAGGTGCGAC	CGTAATCTTCTAATGTTAAGTCTGCGCGTTTA
AATTTCAATCCACGCACCTATACAAGGTGCGAC	TCTGGTGGCGGAGGATGTGTTTATTTACCTTGAA
GATTTCAATCCACGCACCTATACAAGGTGCGAC	TAGATTTAGCAAATTACAGCATTATGGCATTGAT
GATTTCAATCCACGCACCTATACAAGGTGCGAC	TTGAAATAGAAAGTGAATATTGCCATAAGGGTAAAGAG
AATTTCAATCCACGCACCTATACAAGGTGCGAC	ATGGTTCTATTGTTTTGCAAGATAAAGCTTGTGT
AATTTCAATCCACGCACCTATACAAGGTGCGAC

>NZ_CP017762|5|5|3367805-3368240|PILER-CR
ATTTCAATCCACGCACCTATACAAGGTGCGAC	GACAAGTCAAGTCGCCGAGGTAATGCAAATGGATA
ATTTCAATCCACGCACCTATACAAGGTGCGAC	CGTAATCTTCTAATGTTAAGTCTGCGCGTTTAA
ATTTCAATCCACGCACCTATACAAGGTGCGAC	TCTGGTGGCGGAGGATGTGTTTATTTACCTTGAAG
ATTTCAATCCACGCACCTATACAAGGTGCGAC	TAGATTTAGCAAATTACAGCATTATGGCATTGATG
ATTTCAATCCACGCACCTATACAAGGTGCGAC	TTGAAATAGAAAGTGAATATTGCCATAAGGGTAAAGAGA
ATTTCAATCCACGCACCTATACAAGGTGCGAC	ATGGTTCTATTGTTTTGCAAGATAAAGCTTGTGTA
ATTTCAATCCACGCACCTATACAAGGTGCGAC

>NZ_CP017762|5|5|3367805-3368240|CRT
ATTTCAATCCACGCACCTATACAAGGTGCGAC	GACAAGTCAAGTCGCCGAGGTAATGCAAATGGATA
ATTTCAATCCACGCACCTATACAAGGTGCGAC	CGTAATCTTCTAATGTTAAGTCTGCGCGTTTAA
ATTTCAATCCACGCACCTATACAAGGTGCGAC	TCTGGTGGCGGAGGATGTGTTTATTTACCTTGAAG
ATTTCAATCCACGCACCTATACAAGGTGCGAC	TAGATTTAGCAAATTACAGCATTATGGCATTGATG
ATTTCAATCCACGCACCTATACAAGGTGCGAC	TTGAAATAGAAAGTGAATATTGCCATAAGGGTAAAGAGA
ATTTCAATCCACGCACCTATACAAGGTGCGAC	ATGGTTCTATTGTTTTGCAAGATAAAGCTTGTGTA
ATTTCAATCCACGCACCTATACAAGGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_072741903.1\|3369386_3370712_+\|6-phospho-alpha-glucosidase	unknown	unknown	gnl\|CDD\|133434
NZ_CP017762.1\|WP_050351244.1\|3371663_3373067_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273920
NZ_CP017762.1\|WP_072741901.1\|3365283_3366294_+\|PTS-fructose-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224218
NZ_CP017762.1\|WP_072740903.1\|3373561_3374950_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NZ_CP017762.1\|WP_072741899.1\|3364495_3364963_+\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|273298
NZ_CP017762.1\|WP_050353426.1\|3376161_3376710_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP017762.1\|WP_072741895.1\|3357883_3358429_+\|PTS-glucitol/sorbitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|367578
NZ_CP017762.1\|WP_072741902.1\|3366315_3367500_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|224090
NZ_CP017762.1\|WP_083547287.1\|3359536_3359902_+\|PTS-glucitol/sorbitol-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|367683
NZ_CP017762.1\|WP_072741896.1\|3358444_3359443_+\|PTS-glucitol/sorbitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226255
NZ_CP017762.1\|WP_072741904.1\|3377465_3378347_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213231
NZ_CP017762.1\|WP_156875351.1\|3362536_3364489_+\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
NZ_CP017762.1\|WP_072741905.1\|3379614_3380754_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050351241.1\|3378346_3379603_+\|ABC-transporter-permease	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741894.1\|3357432_3357858_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|369138
NZ_CP017762.1\|WP_072741897.1\|3360083_3360752_+\|fructose-6-phosphate-aldolase	unknown	unknown	gnl\|CDD\|188643
NZ_CP017762.1\|WP_050351247.1\|3368508_3369228_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP017762.1\|WP_050351245.1\|3370915_3371659_+\|chitin-disaccharide-deacetylase	unknown	unknown	gnl\|CDD\|212114
NZ_CP017762.1\|WP_072741900.1\|3364959_3365268_+\|PTS-fructose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99911
NZ_CP017762.1\|WP_050351243.1\|3376706_3377465_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_072741903.1\|3369386_3370712_+\|6-phospho-alpha-glucosidase	gnl\|CDD\|133434	cd05298, GH4_GlvA_pagL_like, Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases. Bacillus subtilis GlvA and Clostridium acetobutylicum pagL are 6-phospho-alpha-glucosidase, catalyzing the hydrolysis of alpha-glucopyranoside bonds to release glucose from oligosaccharides. The substrate specificities of other members of this subgroup are unknown. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP_PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases, which include 6-phospho-beta-glucosidases, 6-phospho-alpha-glucosidases, alpha-glucosidases/alpha-glucuronidases (only from Thermotoga), and alpha-galactosidases. Members of this subfamily are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP017762.1\|WP_050351244.1\|3371663_3373067_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273920	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.22629e-121
NZ_CP017762.1\|WP_072741901.1\|3365283_3366294_+\|PTS-fructose-transporter-subunit-IIC	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	6.49939e-81
NZ_CP017762.1\|WP_072740903.1\|3373561_3374950_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.29345e-176
NZ_CP017762.1\|WP_072741899.1\|3364495_3364963_+\|PTS-transporter-subunit-EIIA	gnl\|CDD\|273298	TIGR00848, Includes:_Phosphotransferase_enzyme_IIA_component, PTS system, fructose subfamily, IIA component. 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	2.74779e-41
NZ_CP017762.1\|WP_050353426.1\|3376161_3376710_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.71155e-28
NZ_CP017762.1\|WP_072741895.1\|3357883_3358429_+\|PTS-glucitol/sorbitol-transporter-subunit-IIC	gnl\|CDD\|367578	pfam03608, EII-GUT, PTS system enzyme II sorbitol-specific factor.	1.05522e-94
NZ_CP017762.1\|WP_072741902.1\|3366315_3367500_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	9.29788e-151
NZ_CP017762.1\|WP_083547287.1\|3359536_3359902_+\|PTS-glucitol/sorbitol-transporter-subunit-IIA	gnl\|CDD\|367683	pfam03829, PTSIIA_gutA, PTS system glucitol/sorbitol-specific IIA component.	3.14499e-51
NZ_CP017762.1\|WP_072741896.1\|3358444_3359443_+\|PTS-glucitol/sorbitol-transporter-subunit-IIB	gnl\|CDD\|226255	COG3732, SrlE, Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism].	3.77904e-167
NZ_CP017762.1\|WP_072741904.1\|3377465_3378347_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	5.55805e-102
NZ_CP017762.1\|WP_156875351.1\|3362536_3364489_+\|PRD-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.33823e-38
NZ_CP017762.1\|WP_072741894.1\|3357432_3357858_+\|transcriptional-regulator	gnl\|CDD\|369138	pfam06923, GutM, Glucitol operon activator protein (GutM). This family consists of several glucitol operon activator (GutM) proteins. Expression of the glucitol (gut) operon in Escherichia coli is regulated by an unusual, complex system which consists of an activator (encoded by the gutM gene) and a repressor (encoded by the gutR gene) in addition to the cAMP-CRP complex (CRP, cAMP receptor protein). Synthesis of the mRNA, which initiates at the promoter specific to the gutR gene, occurs within the gutM gene. Expressional control of the gut operon appears to occur as a consequence of the antagonistic action of the products of the autogenously regulated gutM and gutR genes.	4.08396e-39
NZ_CP017762.1\|WP_072741897.1\|3360083_3360752_+\|fructose-6-phosphate-aldolase	gnl\|CDD\|188643	cd00956, Transaldolase_FSA, Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea. Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea, which are member of the MipB/TalC subfamily of class I aldolases. FSA catalyze an aldol cleavage of fructose 6-phosphate and do not utilize fructose, fructose 1-phosphate, fructose 1,6-phosphate, or dihydroxyacetone phosphate. The enzymes belong to the transaldolase family that serves in transfer reactions in the pentose phosphate cycle, and are more distantly related to fructose 1,6-bisphosphate aldolase.	1.25477e-73
NZ_CP017762.1\|WP_050351247.1\|3368508_3369228_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.88724e-73
NZ_CP017762.1\|WP_050351245.1\|3370915_3371659_+\|chitin-disaccharide-deacetylase	gnl\|CDD\|212114	cd10803, YdjC_EF3048_like, Enterococcus faecalis EF3048 and similar proteins. This subfamily is represented by a putative cellobiose-phosphate cleavage protein EF3048 from Enterococcus faecalis v583. It is similar to Escherichia coli YdjC, a hypothetical protein encoded by the celG gene. EF3048 might function as a homodimer. Each of the monomers consists of a (beta/alpha)-barrel fold that forms an active homodimer. The molecular function of the EF3048 is unclear.	1.87104e-113
NZ_CP017762.1\|WP_072741900.1\|3364959_3365268_+\|PTS-fructose-transporter-subunit-IIB	gnl\|CDD\|99911	cd05569, PTS_IIB_fructose, PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and FruB) each containing 3 domains. The FruA protein contains two tandem nonidentical IIB domains and a C-terminal IIC transmembrane domain. Both IIB domains of FruA are included in this alignment. The FruB protein (also referred to as diphosphoryl transfer protein) contains a IIA domain, a domain of unknown function, and an Hpr-like domain called FPr (fructose-inducible HPr). This familiy also includes the IIB domains of several fructose-like PTS permeases including the Frv permease encoded by the frvABXR operon, the Frw permease encoded by the frwACBD operon, the Frx permease encoded by the hrsA gene, and the Fry permease encoded by the fryABC (ypdDGH) operon. FruAB takes up exogenous fructose, releasing the 1-phosphate ester in to the cytoplasm in preparation for metabolism primarily via glycolysis. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include fructose, chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, and a sensory system with similarity to the bacterial bgl system.	5.87749e-40

>NZ_CP017762.1|WP_072741902.1|3366315_3367500_+|pyridoxal-phosphate-dependent-aminotransferase
MKKQFDKVVERRGTYCTQWDYIEDRFGEKNILPFSISDMDFQTPVEIRNRIKEWTDHGVFGYTRWNNSDYKNAIVTWYKKRHDADIVSEWIIYSPSVIYSISQLIALLTRKNDAIVMQTPAYDAFFKTIKQSERKLIKNPLLYEDGYYKIDWIDLEKKLAKSESKVFLLCNPHNPTGRVWRREEIIKIVKLCDCYGVKVISDDIHMDIIYRENKYIPIINVASELNNVFICTSGSKTFNTPSLGGSYVIIPDHKVRSKYLSLMKDRDGLGSAPIFGMVALIEGYNYAEYWVDELRKYLYQNMEIVYDYLKKELPLLHFSIPESTYLAWIDASKLNASNKKIQDYLVHVGKVGIMSGEVYGETEKFLRMNIGCPKEKLYDGLEKLKFSVNHMLNA
>NZ_CP017762.1|WP_072741901.1|3365283_3366294_+|PTS-fructose-transporter-subunit-IIC
MNNVKKHLMTGVSYMIPIVVAGGILLSLGVIIGEETAIGEQLVNYGVWTLGLMVPMIAGYISYSIADRPGVAVGLASGVFASELGTGYIGGILVGFFAGWITNQLKKIPMHHHIAVIKPIMIIPLLGIGASALFMYIISIPLTPAMEGLEKWLVSLEGSNLLFLGFIIAAMMAFDMGGPVNKIALAFAYATLAEGIYAPMAACWIGIMAAPLGLGLSTLIFPKKFSKSEKGNSVPAIIMGSLGITEGAIPYAVATPLKVIPVITLASGIGGGIALVLGAKAPIPAAIGIWGLPFVQKPLMLLVGLLISIVTIALVVGLIRKESDVNEEEEGQLMFE
>NZ_CP017762.1|WP_072741900.1|3364959_3365268_+|PTS-fructose-transporter-subunit-IIB
MNILAVTACPAGVAHTYMAKRALEKAAKEKGYKIKVETQGSMGIENELKEKEINKADVIIIAADTKIEKANRFMEKNVYETSVSSAVKNASKVIDSATEELA
>NZ_CP017762.1|WP_072741899.1|3364495_3364963_+|PTS-transporter-subunit-EIIA
MKNIELINEKLIGMESNATTKEEALYEVATIAYKAERVTNKELYYKSLVDRERESTTGFGNGFAIPHAKEDIVKQPTIIVVRLNNAVNWNSLDNKPVKMLVALAIPKKYKGTMHLKLLANLSENLMEEEFRKQLLYSTNKDGICTTIKNIMEELT
>NZ_CP017762.1|WP_156875351.1|3362536_3364489_+|PRD-domain-containing-protein
MQKILTCFLNADGYLTSSYLAKQVGCSAKTVREDIKKLNSELSNICMVILPKRGSGYKLIGENKDELTKRFIHDTNVVISKALQNPVTPEERMRFIVKKLLYTNNCVTISDFATELYVSESTIKNDIKHAKEILNKYNIKIRKGVTGLYAVGHEINKRFCIADFLYQNSKIDEQVIINYMYIENEATNKIIKDIKKTILDILTEENMTISDYTLKKITIHIVIAINRIKNGQYIEFNSERLHQLTNEQEFKTAEKIIASISQKYKMYFFSPEEIAYITMHLIGNRIAKKNQIASNLHELISDEMLKLSLSVIEEVNNNLKGLDLLKDEELIYSLGIHLKQLLNRLDFQMNISNPFLNTVKIKYPLAFEAGVTAAKRIMKETNFKIGDNEIGFLAMHFGAAIEKQKYQQLVKRKKIALVCASGTATSNLLLTKLSHVLEPGYRMMGVYSFHQIEELLAQKPDLILTTVPLLQKINIPVISISNILGEEDILILREDLDKYHRGEKSLVHLMKKNLFFNDVNMNNKKELLHYLTNKMIDAGYITHKIKDSIFLRESIASTAIGNKVAIPHPINIEVSKSCICTAILNNEMDWDKDEKVVIVFIIVLENKWAPYFQEIFSELYSLTSSYDSIGDLQTKNNFDDFIKDITAKLG
>NZ_CP017762.1|WP_072741897.1|3360083_3360752_+|fructose-6-phosphate-aldolase
MKLFIDSANVEQIKKINNDYPVDGVTTNPSLIAKENRSLFPLINEIRNIIGETKLLFVQTISVDSDSIVNEALQIWENLNRNVIIKIPVTVEGIRAIGILKKHGVKTLATTVYTPMNAYIAAKAGANFVAPYVNRIENLNGNGTQVIKEIRQIFSNAKFSSEIISASFKNVQQIKAVSLSGSDGITVNPQLIEKFLQVPSIKEDVQQFNLDWETVRDEVDSN
>NZ_CP017762.1|WP_083547287.1|3359536_3359902_+|PTS-glucitol/sorbitol-transporter-subunit-IIA
MILKYETTVDRVGAHAATFLEEKMLILFGKDAPAELEDYCLSIVINDLKESINVGDILQLNDREYRITAVGEAVEKNLATLGHITLNFDGSQIPELPGTLYLEDRPISEVDIGDEIKIYER
>NZ_CP017762.1|WP_072741896.1|3358444_3359443_+|PTS-glucitol/sorbitol-transporter-subunit-IIB
MSKYQSIKITRGSNGFGGPLWITPTEQKNKVVYITGGEKPDIADRIAELTGCELVNGFKTTVPESEIACVIIDCGGTLRCGLYPQKRIPTINIMSTGKSGPLAKHITEDIYVSGVKKGNIQLAEEENEQQEMETSQAAKKQYNYTADKKISEQQKPKGLMAKIGITMGNIVTVFYQAGRDAIDTVIKTILPFMAFVSMLIGVIIESGIGDLFAKFLSPFAGSIWGLIVIALICSFPLLSPFLGPGAVIAQVIGTLIGVEIGKGNIPPNLALPALFAINSQASADFVPVGLGLAEAEPETVEVGVPSVLYGRFLTGAPTVFIAWLASFGLYDG
>NZ_CP017762.1|WP_072741895.1|3357883_3358429_+|PTS-glucitol/sorbitol-transporter-subunit-IIC
MDIIITGAEKFMDFFRHGGDVFVGLITDIVPLLIMLLVAMNSLVRLVGEERVEKLAKKSGKNPFTRYFVLPVIGTFVLANPMTLSLGRFLPEKHKPSYYAAASFSCHTHNGLFPHVNPGELFVFLGVAAGITTLGFDTAELALRYFLVGIVTNFFRGWITDYMTSYVSKQQNVKLKQTVEL
>NZ_CP017762.1|WP_072741894.1|3357432_3357858_+|transcriptional-regulator
MFWYLIILIGVAWLAQSIFGFLQIRHFNRNYAELRALGRVAIGKRTGLFRAGTVVMFCIDKQDRILMAKRMQGVTVMSRVKDLTGFTGKKLLQMKESDYKHVNKLTKIAIQDAINSYDILSKGGELQVKKGWLERLFSKKK
>NZ_CP017762.1|WP_050351247.1|3368508_3369228_-|GntR-family-transcriptional-regulator
MWNNSLPLYRQIANKIKEDIIGSKLAKGDAIPAEAKLAKTYEVSRVTVRQAIKLLVEEGLLYSIQGSGTYVAHNKVEHNILHLQGFTEEMQKLQNNPKNEVLEFKLTDPTDEVQEILNISNNEKVYYMKRLRYADHEPFLLEESFLPVDLFPDFSIEVIKKSKYNYIENKGYTIDKRYGELIPILPNEELKKILQLQDNQPLLFLKAFTVFEDGKPFEYSKVYYHPKKYSFKFISEKNH
>NZ_CP017762.1|WP_072741903.1|3369386_3370712_+|6-phospho-alpha-glucosidase
MKKQNLVIVGGGSTYTIGMIMSLIAEKKNFPLNSITFYDNDEKRQEKVAKATSIILDEYYPELESFHYTTDKETAFTGIDIAFIQIRTGGLQMRELDEQIPLKYGVVGQETCGPGGMAYGLRSIRDMIELVYDIKKYSKDAWILNYTNPAAIVAEALKREFPQDPKLLNICDMPIAIMHSFATMLNKNIWDLVPSYFGLNHFGWFTKIEDSEGNDLTQIIKDTIMGEGFVPTDQEIANDQSWQQTFEQARKMLIDFPEFLPNTYLQYYLYPDDLAKKESLTNTRARQVINGREKRITELCNQIIQDKSTKNVELHVDIHGVYMVKAAASLVYNLKQTYIVMVENNGIISNIPDDATVEVPALLTASGPKPFSVGKIPTFYKGLIENQFAYEKLVADAYFENSYTKALQALTLNRTVVHVPTAKAILDDLIEANKGYWPELQ
>NZ_CP017762.1|WP_050351245.1|3370915_3371659_+|chitin-disaccharide-deacetylase
MKKLIINADDFGYSRSVNYGIIDAHTDGVLTSTTLMTNMPGAEHAYQLGEKHKTLGIGVHLTLTCGKPILKNHHTLVDADGNFKKLYHYQKLFHIDTNELYAEWKAQIEAFLDSGLAPTHLDSHHHINNLEPILPVFLELAKEYKLPVRHNFKIKPEFGTLITTDHFEYNPEILLGDVNTIVEEYKEAQTIEIMCHPAYLDKSLMTGSSYATPRIEELAMLIHPDVKKKLQQHFQLMTYRELEKEEA
>NZ_CP017762.1|WP_050351244.1|3371663_3373067_+|PTS-transporter-subunit-EIIC
MRKFMQKLGKSMLIPIVAMPIAGILFRLSAGDLLDWKLFQAAGVIFANMDMLIAIGIAMGLAKTKDRGIPALTGFLAITVLNEGLTLMNPDLDMSVFGGVIAGLIAAGIYNRFKDTKLPSMFSFFGGEKFPITMIILTMIPVAGIFSLIWPYAQQGIDSFAQALVGLGAVGIFIFGFLNRFLLPFGLHHVLNTYIYFGLGSYENASGEVVTGEITRFMNGDPTAGYFLGGFFIVMIFGVPAIALAIARAAHKKKKAETKALMSSGALTSVVAGLTEPIEFTFIFTSPLLYFIHSVYTGLAGATLYLFGVRHGFSWGGSVIDYGLNLSLSDSGLMIIPIGLAFGLLYYFTFYTIIVKKNIKVIGREDDVEFGFQADEKEQSLKLSHNKFEYMAKKILENIGGKENVVDYENCMTRLRLVVKDASLVDEDKIKQTGAHGVVKVDNKHIQIIIGPEAGTVLTEFKKHIEK
>NZ_CP017762.1|WP_072740903.1|3373561_3374950_+|group-II-intron-reverse-transcriptase/maturase
MRQLQKTGESGYRQRDSVEHEGYVEAHSTFHGEQNNQNGVSNLFERILSRNNLNQAYLQVVRNKGAAGIDGMTYDQLLPYLKEHKEELLTQLRQGKYKPQPVLRVEIPKPDGGKRKLGIPTVIDRMLQQAINQVLQPIFEPTFSDNSFGFRPKRSAHHAIIRAKSYYEQGYKYVVDLDMKSYFDTVNHDKLMYFVEKQISDKRVLHLIRRYLLSGIMINGIFEKSEQGTPQGGNLSPLLSNIYLNELDQLLEKRGHRFVRYADDCNIYVKSRRAGYRVMDNITTFLERDLSLTVNREKSAVGSPLKRKFLGFCLLATKNGVKIRPHNKAKVTVQEKLKRITKRNRGRNLEVILKEIQQLMTGWINYYGIGEMKGFMKNLNGWLKRRIRQYIWKQWKNPRTKRKNLIHLGIDKRKAYEWSNTRKGYWTISSSYVLHRSLTDKELASRGYKDIALQYQFVHSNY
>NZ_CP017762.1|WP_050353426.1|3376161_3376710_+|sigma-70-family-RNA-polymerase-sigma-factor
MTQEMKWIKAIKKKSSEQAANQLISKYYHEVFGFIYKQTLDRELTKDITQDIFISVLRTIHSFDGRASFRTWLYKIANSRLIDHYRSKYYKQNKKTEPIDEKTVYESIEFTIDVETKDEARKVLEVLARFDRELQQIVRLKIYGEYTFSEIAASLELPESTVKTKYYATIRKLKNILKGEWR
>NZ_CP017762.1|WP_050351243.1|3376706_3377465_+|hypothetical-protein
MKNNSKDIPYLDEKSMQREISTIIINGLDPKASFWSYLATIYQQIGFKFMFKDFVEIIFTLLISVIIVLAFILSTIEYIHIRNVNLYTIVFIWSPMTYMVMAYLFFVNQKQKTTYEVEMTCKYNLHQLAAFRMLMFSVISMIMNGLFIYALMFQHALNYFYAFLLSSSSLFLFALVFLYVQFHTKTRASKIILLIMWLFSNLLASYYSTSFYLNFLKQIPFYVYGVITIVAIVFYVKSLKGLLFTQKMKGLI
>NZ_CP017762.1|WP_072741904.1|3377465_3378347_+|ABC-transporter-ATP-binding-protein
MLVLKDVSKKFGNFTALEDINLEFNNGIYGLLAPNGAGKTTLIKMLVTLLFPTKGEIEYDGTEITSLDEQYRNVLGYLPQEFGYYKNYTSEKYLNYLAALKGLDKKETKKRISELLELVGLGDVTRKKMKKFSGGMIQRVGIAQAVLNDPKILILDEPTAGLDPKERARFRKILTTLARDRIIILSTHIVSDVESIAKEIIMIKNKTILYKDTVANISNTLDGKVFEAEVSFSDLNVIREKYQILSERQEREKMTIRFITSDQTNEKWKRVTPTLEDVFLYVYEDDETLAGSV
>NZ_CP017762.1|WP_050351241.1|3378346_3379603_+|ABC-transporter-permease
MIIKEELLKLVKMPIIPVIILFFMALNTVIVMSHSYFKEDLSVLTDLVDTYGYEINENMMKEFGKDYQDKIAWVNEVAPDDNKVYQHSSELLSDDSIHYENRLSNSDYQRLLKYSIIEGYYLTAQDIDKAYDSIDLDGSAEYLIRMYGFTDSAAEEIRAQYQKLALRLDELIDNGEHKNLFFTGKIYKMHSLLFKDIGRALIFELMILVVLITATITNYEFEHRTALVTYTTKRGRKLIIDKLIAAMITNGCVMFGLIGMTLGAFFLTYDYSGLWNVPISNFFNTEMPLPYISWWNLSFIEYVVFFVLFIVITQLLFMGVCLILSIYLKNTYLVFFAFLILLGLGIAIPGFAPMNSKLVFLLHFNPFAFILNPHEWLMGNGPFTIHCYYEIVTIVLWVFLLGIVGSYSVYRFYRQQLQ
>NZ_CP017762.1|WP_072741905.1|3379614_3380754_+|hypothetical-protein
MRIIWYEIRKLLNWKVLGLVLLISLLFFEQFLRFDFEHFPNGRPEGDTFNVTKQMINKYGQEMDEREFQDFKETYKEEVNKANAYLQSRDDFAEVGVTTYEQLTNMDQENENETINELFNDVMFDKGIDVFWELQSREAIIEYYEVRKEFFNGETASIDAPEWKQKILDGSINEILPSFVIENYNNLITMLSILIILSVMIVVGRIFIIDQQNNAIYLQYTTNIGRKLFKKKLMASMITSFLITSVYIGAFLILYSFNDTQIFFESSLHSFNAFTFNWLDMTFLQYIYLTIIGVYLLALVAAAVTTYLSRVVSNYISLIGVQVPIAVVLIILIFEYLVSNLFNTAYPMWITIGTYLGLLVLGASFLIVRWKKERKIDIV

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Crispr_ID: NZ_CP017762_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_6

3429728-3430294

Orphan

NA:I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCTATATAAGGTGCGAC	PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACCTANNNNANG	CRT

8 spacers

The CRISPR arrays of NZ_CP017762_6

>merge|NZ_CP017762|6|3429728-3430294|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATCCACGCACCTATATAAGGTGCGACTATCCGTAAGTAATATGTTTGGGAGATTTTCAGATATTTCAATCCACGCACCTATATAAGGTGCGACGCAAGTTAGATAAAATACCAGAAGGTGCACCAAACATTTCAATCCACGCACCTATATAAGGTGCGACATGTCAAATTTAATTGAATTTGAAGATGAACTAATTTCAATCCACGCACCTATATAAGGTGCGACAGAAACAATAGTACAGGGAGGGTTTTAAGTAAGAATTTCAATCCACGCACCTATATAAGGTGCGACGATGGACGAACACCATATTTTCATACAGCCTACGCATTTCAATCCACGCACCTAGTATAAGGTGCGACTATAGTTTCCTGTTTCTTTTTCCTGTTCTTCTTTATTTCAATCCACGCACCTAGTATAAGGTGCGACGTTATGACAGTTGGAACATAGCAAACTTTTTAAGTATTTCAATCCACGCACCTAGTATAAGGTGCGACAAGGGAGTGAGCAGGTTGGCTGATTATTTAAAACATTTCAATCCACGCACCTAGTATAAGGTGCGAC

>NZ_CP017762|6|6|3429728-3430294|PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGACT	ATCCGTAAGTAATATGTTTGGGAGATTTTCAGATA
TTTCAATCCACGCACCTATATAAGGTGCGACGC	AAGTTAGATAAAATACCAGAAGGTGCACCAAACAT
TTCAATCCACGCACCTATATAAGGTGCGACATG	TCAAATTTAATTGAATTTGAAGATGAACTAATT
TCAATCCACGCACCTATATAAGGTGCGACAGAA	ACAATAGTACAGGGAGGGTTTTAAGTAAGAATTT
CAATCCACGCACCTATATAAGGTGCGACGATGG	ACGAACACCATATTTTCATACAGCCTACGCATTTC
AATCCACGCACCTAGTATAAGGTGCGACTATAG	TTTCCTGTTTCTTTTTCCTGTTCTTCTTTATTTC
AATCCACGCACCTAGTATAAGGTGCGACGTTAT	GACAGTTGGAACATAGCAAACTTTTTAAGTATTTC
AATCCACGCACCTAGTATAAGGTGCGACAAGGG	AGTGAGCAGGTTGGCTGATTATTTAAAACATTTC
AATCCACGCACCTAGTATAAGGTGCGAC

>NZ_CP017762|6|6|3429728-3430024|CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TATCCGTAAGTAATATGTTTGGGAGATTTTCAGAT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GCAAGTTAGATAAAATACCAGAAGGTGCACCAAAC
ATTTCAATCCACGCACCTATATAAGGTGCGAC	ATGTCAAATTTAATTGAATTTGAAGATGAACTA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	AGAAACAATAGTACAGGGAGGGTTTTAAGTAAGA
ATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|6|6|3429728-3430287|CRT
ATTTCAATCCACGCACCTATATAAGG	TGCGACTATCCGTAAGTAATATGTTTGGGAGATTTTCAGAT
ATTTCAATCCACGCACCTATATAAGG	TGCGACGCAAGTTAGATAAAATACCAGAAGGTGCACCAAAC
ATTTCAATCCACGCACCTATATAAGG	TGCGACATGTCAAATTTAATTGAATTTGAAGATGAACTA
ATTTCAATCCACGCACCTATATAAGG	TGCGACAGAAACAATAGTACAGGGAGGGTTTTAAGTAAGA
ATTTCAATCCACGCACCTATATAAGG	TGCGACGATGGACGAACACCATATTTTCATACAGCCTACGC
ATTTCAATCCACGCACCTAGTATAAG	GTGCGACTATAGTTTCCTGTTTCTTTTTCCTGTTCTTCTTT
ATTTCAATCCACGCACCTAGTATAAG	GTGCGACGTTATGACAGTTGGAACATAGCAAACTTTTTAAGT
ATTTCAATCCACGCACCTAGTATAAG	GTGCGACAAGGGAGTGAGCAGGTTGGCTGATTATTTAAAAC
ATTTCAATCCACGCACCTAGTATAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_050351205.1\|3427876_3428383_+\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NZ_CP017762.1\|WP_156875353.1\|3426746_3426914_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050351208.1\|3424958_3426185_+\|FAD-dependent-monooxygenase	unknown	unknown	gnl\|CDD\|223727
NZ_CP017762.1\|WP_050351209.1\|3423895_3424681_-\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP017762.1\|WP_072741922.1\|3428401_3429514_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|225969
NZ_CP017762.1\|WP_072741923.1\|3430772_3431984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372705
NZ_CP017762.1\|WP_050351207.1\|3426207_3426750_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050351196.1\|3439352_3439622_+\|30S-ribosomal-protein-S14	unknown	unknown	gnl\|CDD\|181574
NZ_CP017762.1\|WP_072741918.1\|3421382_3422753_+\|xanthine/uracil/vitamin-C-permease	unknown	unknown	gnl\|CDD\|366341
NZ_CP017762.1\|WP_050351192.1\|3446141_3446819_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP017762.1\|WP_072741928.1\|3439743_3440709_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_CP017762.1\|WP_050351199.1\|3433316_3434384_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP017762.1\|WP_072741924.1\|3432422_3432836_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741930.1\|3443646_3446145_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP017762.1\|WP_072741921.1\|3426927_3427875_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP017762.1\|WP_072741917.1\|3420766_3421198_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP017762.1\|WP_072741925.1\|3434617_3435346_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741929.1\|3440748_3441870_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379355
NZ_CP017762.1\|WP_072741919.1\|3423141_3423909_-\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP017762.1\|WP_050351201.1\|3432067_3432316_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274963

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_050351205.1\|3427876_3428383_+\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	9.37962e-11
NZ_CP017762.1\|WP_050351209.1\|3423895_3424681_-\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.5593e-50
NZ_CP017762.1\|WP_050351208.1\|3424958_3426185_+\|FAD-dependent-monooxygenase	gnl\|CDD\|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	3.52602e-59
NZ_CP017762.1\|WP_072741922.1\|3428401_3429514_+\|cupin-domain-containing-protein	gnl\|CDD\|225969	COG3435, COG3435, Gentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	2.11826e-143
NZ_CP017762.1\|WP_072741923.1\|3430772_3431984_-\|hypothetical-protein	gnl\|CDD\|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.24933e-09
NZ_CP017762.1\|WP_050351196.1\|3439352_3439622_+\|30S-ribosomal-protein-S14	gnl\|CDD\|181574	PRK08881, rpsN, 30S ribosomal protein S14; Reviewed.	3.12101e-46
NZ_CP017762.1\|WP_072741918.1\|3421382_3422753_+\|xanthine/uracil/vitamin-C-permease	gnl\|CDD\|366341	pfam00860, Xan_ur_permease, Permease family. This family includes permeases for diverse substrates such as xanthine, uracil, and vitamin C. However many members of this family are functionally uncharacterized and may transport other substrates. Members of this family have ten predicted transmembrane helices.	1.88294e-06
NZ_CP017762.1\|WP_050351192.1\|3446141_3446819_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.40864e-106
NZ_CP017762.1\|WP_072741928.1\|3439743_3440709_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	3.25136e-108
NZ_CP017762.1\|WP_050351199.1\|3433316_3434384_+\|hypothetical-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0.00177563
NZ_CP017762.1\|WP_072741930.1\|3443646_3446145_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	9.11802e-09
NZ_CP017762.1\|WP_072741921.1\|3426927_3427875_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	6.64933e-100
NZ_CP017762.1\|WP_072741917.1\|3420766_3421198_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	2.50601e-22
NZ_CP017762.1\|WP_072741929.1\|3440748_3441870_+\|hypothetical-protein	gnl\|CDD\|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	1.14014e-114
NZ_CP017762.1\|WP_072741919.1\|3423141_3423909_-\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	9.39376e-57
NZ_CP017762.1\|WP_050351201.1\|3432067_3432316_+\|hypothetical-protein	gnl\|CDD\|274963	TIGR04075, Ser/Thr_phosphatase_family_protein, polynucleotide kinase-phosphatase. Members of this protein family are the bacterial polynucleotide kinase-phosphatase (Pnkp) whose genes occur paired with genes for the 3' terminal RNA ribose 2'-O-methyltransferase Hen1. All members of the seed alignment belong to a cassette with the Hen1. The pair acts in bacterial RNA repair. This enzyme performs end-healing reactions on broken RNA, preparing from the RNA ligase to close the break. The working hypothesis is that the combination of Pnkp (RNA repair) and Hen1 (RNA modification) serves to first repair RNA damage from ribotoxins and then perform a modification that prevents the damage from recurring. [Transcription, RNA processing].	0.000278926

>NZ_CP017762.1|WP_072741922.1|3428401_3429514_+|cupin-domain-containing-protein
MAEKASYLHDKDVKDFTKDIQQYNLGPLWEAIPEVMNKNPEPHAQAYLWSSELIEKKLTEAAQIFTPERGGERRAIYFQNPGLTYRKPWGQVSTTQTLYAAVQLLLPGEEAPSHRHTQSALRFITEGEGAYTIVQGERIFMEEGDFLITPKNLWHGHGHLGNKPMIWMDALDIPTVYNIGGTFFEPYEDGLQQPNVPDNFSEKRYRGGMVRPVGDDKYDVAPLANYKWSRTVDAIKGLMEFDPDPNYGFAVDYMNPTTGKSANPTMGTRMQFLPKEFNTKSLRHTHSTIYHAYKGSGYTIINGVRFDWKAGDYFVVPNWAWYEHVPAEDSYLFSVNDIPIMDRFELERVEQYERNNGHQTVTGEFKPDFR
>NZ_CP017762.1|WP_050351205.1|3427876_3428383_+|DinB-family-protein
MASTKVEGYVESIHQSLDNILSIVSYLSEDMIRWKPSRDEWSILQILSHVGESTLFWLDEMDRVLEKPGTEWGRGLGHSGRLAAVEAPDKLTIDDAIAKVNGLKEEVTNRLSKVSEDRLTEENPHRNFGKFGNKPISFLIEHFLVEHVEGHYNQIQRNLTKLSEETIK
>NZ_CP017762.1|WP_072741921.1|3426927_3427875_+|fumarylacetoacetate-hydrolase-family-protein
MKLITYKANGYVRIGAFIDEDTIIDLNYAYQAQLQSEGKYRYREIAEAFVPPAMEAFLQGGKESLEIAKKATNFALEIPAYQHKLVYKKEEIKVEAPLNKPGKMICVGHNYREHILEMGRELPSHPVVFSKFANTIIGPEDDIPYYPLSEQLDYEAEFAFVVGKQARNVLEEDALDYVAGYTIVNDVTYRDIQRRTLQWLQGKAVDGSAPMGPWLVTSDELTDPSGLEMVLTVNGEERQRSNTKNLVFTVQKLVTFLSNLMTLEPGDIVLTGTPGGVGVARDPQVFLKDGDVVTIEVDRIGVLKNKVALQQGGDV
>NZ_CP017762.1|WP_156875353.1|3426746_3426914_+|hypothetical-protein
MTNGVVRVLLNKEVLYISMETWRAIDYIYAIIISYKVQIRILEGIMLSAWNEPYF
>NZ_CP017762.1|WP_050351207.1|3426207_3426750_+|hypothetical-protein
MSVVFQEDTSKMTVNQAFEKLTTLGWFKEGGRVEKEIETLMEQFLKQFNIKQYEMKWLHKEELIEVIERFSFQGSDIWNELKEIPDHLKQQISANNDDSYLERLVDILPEAVFHPAFDGAFKQYSEEKTIRFLTGNAMYFALLICIAELASKGDLFQPIFQIIERGHVPVGIEGNMIYLL
>NZ_CP017762.1|WP_050351208.1|3424958_3426185_+|FAD-dependent-monooxygenase
MEAKKYDVIVVGAGPVGLTAGLALRRKGISCAVIEASEKGEPRPGSRAIFLHHASLELLEQTAPGLGFDLARNGVIWPIKRTFYKGKEVYVRNYGVTDNQSRAKLPHFTSLHQHEIESNIYRKCVEAGVEFIYGQLIELVDITKAGVKLMTDQGEKYEAKYAIGCDGARSVVRNQAGLKLEGPRTKDTFLVIDLEEDEEEPLPIERVFHYHHPAMGGRNVMHVPFKNGWRVDLQLLAADDVEEWASLEGVKQWLPKVMDEKYADRITWVSSYQFHQVVADSFTDEKRRILLAGEAAHLFAPFGARGLNSGIPDALIAVRGIERALSCNSEGSRRKAIEDAAKERRIAAKWNRDASTTALHHIQGDSKEMNMKRDLAASLVSLVPRLGRWLDEGPYGPKFGPPELTTKY
>NZ_CP017762.1|WP_050351209.1|3423895_3424681_-|IclR-family-transcriptional-regulator
MPKNQKRTSSLENALALLSLFTMNEPELSVTSVSKKLFISKSTAHRLLSSLVQEGFVYKDARTRLYSLGASVLSLVNIVNSQIHISTEVIPLLNLLVEKTKESAHLSILDHQQTVYIQTIKGVYPCKDQINLGTQRPSYYTAAGQAIIAYHPELYDDLMIDLYTCTSNPVKLPSSFKQRMASIASKGYAISNGEWVKGVTELAVPVYKKHTDVIASISITANSDRITSPTIQKRYIRLLQHAAGELQKMIQLRRIEKDAKR
>NZ_CP017762.1|WP_072741919.1|3423141_3423909_-|IclR-family-transcriptional-regulator
MRKDKEILSSVTNAMRILRLYHTKQRELSFTEIKKKLQFTQGNASRLIAILVKEGFLTKNPRTNHYRLGLSILSLGGAIFSHHEMYREALPIIKDISKSLKETVHLCLMENEKVVYLFRSERKPHPDRLVTQIGRTSPIHCTSEGLCILAFQSKDVIQEFLSKPLYAYTPYTITDAKTLTNCLIEIRKKDYCYLESTYYEGYTSIAVPIRSHTEEVVASLSVIGHSSRFTTDKLNTIITQMKDAGDEISNQLGYI
>NZ_CP017762.1|WP_072741918.1|3421382_3422753_+|xanthine/uracil/vitamin-C-permease
MSVYKRKDGDVQPYWSLGKYQLRLPFIHYRLEIPELIQGLVIFTIGLSMIEIMTSVLGMSYEAALAIAILNHFLMLIPSAFGVPFVSGFITPLIPVLTVFLGNFAPGSEAVRALISVQLVTAVIFLLLGLTGLGKKFIISLPNSLKAGILIGAGIGAIMGEIESGGRVVTTPISLIIGGMLCLYIMFSLHFKRLYEQSKIIKKIANYGIVPAIIVAMVIGWVVGEYPTPKIEWGITVPNLSELWSVTPFVVGFPDLNLLIAAIPTAILAYIIAYGDIVVGDNLIKRASESRKDEKIAYDLNQVHHLTFIRGILNALFVPHPGLAGPIFTAGTASVAERYTFGKKAMQSIFSGTNSLLISLTLSIFILPLVTLFQPFLPIALSITLILTGYLCINVGVQQVKSEEEIGVAVVMAIVLALYGAAYGLIMGAVLYFVIQHVGFRFKKRATEINNDREVM
>NZ_CP017762.1|WP_072741917.1|3420766_3421198_+|acyl-CoA-thioesterase
MVKVKHIHRFKVYFGDTDAAGIVYYPNFYKWMDQASAELVAKAVLPTSRLYKEEKILLPLLEAFCKFQSPLFFEDIVDVHSEVTEINSKTFRVEHVFKREEEFIAKGYEIKAWTRKKEEKLKAEPIPNDIRKKLEFDVESTIS
>NZ_CP017762.1|WP_072741923.1|3430772_3431984_-|hypothetical-protein
MEVHVKVSIPSYNYRGFVARAVCDSKTDWELPESYLAYLEKSHQNKIIYQTKTTEETSKLEFLIQQAHGLYVLIKDHAEVENFRSFEHLARLLKEQSITTKDGSVMPVEGAKLTSQILQNPSDPDATFRHKAGESHIGHSLNFVEVYDNETDMGLIMHADVKENTYSDAQYGEDFVKNHPLAKEMDTLAVDGAYYRQETVKHADELGLEINFSQMTGRAVAEDSIGVDQFKIDPETRKITRCPQGHQPIFSLYDEIKETHTAKFYKEHCQNCPLFERCQVKEQKRAYHISFSENKIRTDQTRSKMGTDRHRKLSNYRAGVEGVPSVLKRAYRLEHLPVRGQVRSNFCLHHRPKLQKMQEIHQKEWSSHFYASYISKKICDQKNFDHKDSTLTFFGNKKLVFGI
>NZ_CP017762.1|WP_050351201.1|3432067_3432316_+|hypothetical-protein
MNWIRNQFIHSTEKAPKTVFFGHTPTGLIHDEKDNYDIWTSEKGDKVDIDGGCAFGGQLDAIKTDKKGNILQKIAIASEMNQ
>NZ_CP017762.1|WP_072741924.1|3432422_3432836_+|hypothetical-protein
MSAYDTPTETCPYCGDEMDTDWVDNGIGMVQRGPYHCQKCHASEIGPQLLDWYYKNREGHTIYLPGKRRYNSLLKKKVKWGTTPVLKSGPPFSEDELKTGYYKGKIPPYANTVAGKLVDHQKDKQMYDIGLLDEKKI
>NZ_CP017762.1|WP_050351199.1|3433316_3434384_+|hypothetical-protein
MRLLNKILGGVALISLVAVFLTSGVNAEEYVKPKFLRAEFAKEAFQAGEPVELTVNSEAGTNEIERVWVQIEHEQTKRLFSSNNVIYSESGTEVKIHLPEEAPSGKYAIQAIIITDSAGVKTNIFNPGASFDLIGESTDTEKAVFQNAVFDKEQYQPGEEVVLKIEATDDESGIDWVFPSIQHLSSEEYTFQGFSEEVNGYHEFRFQLPDNALNGTYGIQYLTIRDHSGNEQDVFDVNATFEVVGGSLDADAPTLKSIAIDKDQYKQGEQVHINIDAEDKSGVKSVFLYVEHKQTGVQYNDFATFNGETFDFNRELPSNAPLGEYEVFAVYLEDNLGNQVSLFNYEPRIEFEVIK
>NZ_CP017762.1|WP_072741925.1|3434617_3435346_-|hypothetical-protein
MRNEKIFLSLFILTCLFFVFGFSHPSNAEKAIVNNKEKSIEESYRDATNGISDIDTSKFGVSSEISAISRNLTSEAPIAIEEYSTAQILSETVDDKGNKDQLIAVTVFNDIELKEEGAKIRTLGDKGNEELTPFVRAYNRIYYQNSTDRGVAYAKLTRVTGGWEVFNPLTTLSNRVVRYGSSGWPNGSQATVKYPIGNTYSYKTPSSWKRTALTGSYAIGTNSTVTVKRGSSTWTVKVKTNL
>NZ_CP017762.1|WP_050351196.1|3439352_3439622_+|30S-ribosomal-protein-S14
MAKKSKIAKEKKRQKMVEQYATLRKELKAKGDYEAIRKLPRDSSPTRLKNRCEVTGRPRGYMRKFNMSRIAFREYAHKGQIPGVKKASW
>NZ_CP017762.1|WP_072741928.1|3439743_3440709_+|GTP-binding-protein
MSQKQTIPVTILTGFLGAGKTTLLNNLLKDMPKQKIAVIINEFGDTSIDSHLVVSTREEIIEINSGCICCNVRGDLINILSNLIAQEEKIDRVIIETTGMANPAPVIQTFLMDEKTGKSFEIDSVITMVDAQHIWLHLKEEEPGKQIAFADILLINKMDLITANEKIKLEQQLVNMNPHAKRVYTTYANVNIQDLIGKKSFDLGNLLKIDPKLLVETHHHHHNDQVTSFVFREGRPLDLEKVNRWFAYLVHFKGENLYRYKGVLHINHLEKRVVFQGVHMLFAGTEGTEWADNEPRQSEIVFIGKHLDYQELAKGFQYCLA
>NZ_CP017762.1|WP_072741929.1|3440748_3441870_+|hypothetical-protein
MITVNKIYDVVIVGAGPSGIGVATLLQQMNCTSYLILEKEEVGASFLRWPEEMRFITPSFPAQGFGQTDLNAIVPKTSPAYTLNMEHPTGEAYAEYLDVVADHFALPIKKGVQVKQIHKKDGIFTIDTTQGIYQSRYVVWAAGQYQYPNLRPFPGAELGVHNSLIPSWRELEGDDFIIIGGYESGMDAAFHLGRFGKKTTIIAKTNTWELDNSDPSIALSTYTYSRVCHLLGSDLLTVVGNTAVTRIEAVSSGYDVYTSSGKVYFTTEKPILATGFIGSTTKIENLVTRGQYDEVLVNEIDESVATSGLFLAGPELRHKDHIFCFIYKFRQRFAIIAETIGYRLNLDLSILEQYQQENFYLKDLSMCGERCQC
>NZ_CP017762.1|WP_072741930.1|3443646_3446145_-|ABC-transporter-permease
MIRVKNKKIIRKLARRNFRSSKVRNVFAVMAIALTTLLFTSLFTLGSGMIKSTQRADMVMSGGDGHARIENMTESEYRTIERHPLIQEMSYIRKLADSVDNAALTKRQTDFWYYDDLQLKYLFIELTSGHKPQEEKEIITDTKTLELLGIPQKLGTPLTLELTINNDKVIREFVLAGWWESHPGVPVGTIISSRAYMDAHLGELESTYRQDQSKTGSITGNLKFANSKNINEKLETVLIDSGFSMNINSQNYLNAGTNPIYLSKSTSAGFGTILLLSSILVLFMLTGYLIIFNIFQISVMRDIRFYGLLKTVGTTGRQLRAIIRRQAWGLSLVGIPLGLFGGFFVGRSMVPTLIEQSQLAGSKAVVSANPLIFVAAIMFTLATVFISIRKPLKMAAKISPVEAVSYTNTNSVSRKKKTKKSSNSGTPRRMALNNLGRNKKHTVLVILSLSLSIVLTNTIFNFSQSVDVDKALQNASDSDFRIGHIDLFNYKYKGKEESALSESLIAAVEKQEGFETGGRQYGSPATYKSETTRQTVNQRLDGSFSTNLIGLDEFSFSRLELLDGELDREKLANGKYILEGVWSDTRGNLDESSMNHSVGDQVKLNYGGNTIEVTVIGHIIANETNTYDWVGSGFFLPGEMYKKLTGNTHAMSYVFDVAEDEEGDMERFLKWYTNSIEPSMNYKSKLTVTAGLTDIQDTIMLIGGTLALIIGIIGVLNFINIILTSVLIRRREFAVLRSIGMTKQQLLKMLCFEGGYYAAWTVAVSILLSIGSSLLIVRPLSAQIWFLTFHFNFWPLVIILPLIFVIGILIPYIIYHATKQQSIVEQLRIEGY
>NZ_CP017762.1|WP_050351192.1|3446141_3446819_-|ABC-transporter-ATP-binding-protein
MTILKTMNLKKIYTNGATSVHALNNVNLSVERGEFVAVVGTSGSGKSTLLHMLGGLDRPTSGTVTVDGKDIFSLKEEALTIFRRRKVGFVFQSFNLVPILNVYENIVLPIQLDGNKPDKSYVNQIIQTLGLDDKLQRLPSQLSGGQQQRVAIARALATKPIIVLADEPTGNLDSKTSQDVIGLLKVTGEKFSQTIVLITHNEEHAQLADRIIRIEDGKILGGDRV

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Crispr_ID: NZ_CP017762_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_7

3438572-3438735

Orphan

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP017762_7

>merge|NZ_CP017762|7|3438572-3438735|CRISPRCasFinder
GTTTCTATTCACGCACCTATATAAGGTGCGACTGTTGAGATAGACGATAAAAATAAAATAATACACATTTCAATCCACGCACCTATATAAGGTGCGACTAATGAGTTAAAGGCAAACGCACCACAGGATGAGATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|7|7|3438572-3438735|CRISPRCasFinder
GTTTCTATTCACGCACCTATATAAGGTGCGAC	TGTTGAGATAGACGATAAAAATAAAATAATACAC
ATTTCAATCCACGCACCTATATAAGGTGCGAC	TAATGAGTTAAAGGCAAACGCACCACAGGATGAG
ATTTCAATCCACGCACCTATATAAGGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_050351205.1\|3427876_3428383_+\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NZ_CP017762.1\|WP_072742457.1\|3447846_3448533_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP017762.1\|WP_156875353.1\|3426746_3426914_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050353472.1\|3449148_3449400_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225215
NZ_CP017762.1\|WP_072741930.1\|3443646_3446145_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP017762.1\|WP_072741922.1\|3428401_3429514_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|225969
NZ_CP017762.1\|WP_072741923.1\|3430772_3431984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372705
NZ_CP017762.1\|WP_050351207.1\|3426207_3426750_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_083547292.1\|3449797_3450187_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214615
NZ_CP017762.1\|WP_050351196.1\|3439352_3439622_+\|30S-ribosomal-protein-S14	unknown	unknown	gnl\|CDD\|181574
NZ_CP017762.1\|WP_072741925.1\|3434617_3435346_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050351192.1\|3446141_3446819_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP017762.1\|WP_072741928.1\|3439743_3440709_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_CP017762.1\|WP_050351199.1\|3433316_3434384_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP017762.1\|WP_072741924.1\|3432422_3432836_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741921.1\|3426927_3427875_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP017762.1\|WP_072741933.1\|3449399_3449732_+\|mRNA-degrading-endonuclease	unknown	unknown	gnl\|CDD\|182138
NZ_CP017762.1\|WP_072741929.1\|3440748_3441870_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379355
NZ_CP017762.1\|WP_156875354.1\|3446926_3447847_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP017762.1\|WP_050351201.1\|3432067_3432316_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274963

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_050351205.1\|3427876_3428383_+\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	9.37962e-11
NZ_CP017762.1\|WP_072742457.1\|3447846_3448533_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.54508e-71
NZ_CP017762.1\|WP_156875354.1\|3446926_3447847_-\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	8.17734e-42
NZ_CP017762.1\|WP_050353472.1\|3449148_3449400_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|225215	COG2336, MazE, Growth regulator [Signal transduction mechanisms].	2.26113e-20
NZ_CP017762.1\|WP_072741930.1\|3443646_3446145_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	9.11802e-09
NZ_CP017762.1\|WP_072741922.1\|3428401_3429514_+\|cupin-domain-containing-protein	gnl\|CDD\|225969	COG3435, COG3435, Gentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	2.11826e-143
NZ_CP017762.1\|WP_072741923.1\|3430772_3431984_-\|hypothetical-protein	gnl\|CDD\|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.24933e-09
NZ_CP017762.1\|WP_083547292.1\|3449797_3450187_+\|hypothetical-protein	gnl\|CDD\|214615	smart00318, SNc, Staphylococcal nuclease homologues.	4.50288e-29
NZ_CP017762.1\|WP_050351196.1\|3439352_3439622_+\|30S-ribosomal-protein-S14	gnl\|CDD\|181574	PRK08881, rpsN, 30S ribosomal protein S14; Reviewed.	3.12101e-46
NZ_CP017762.1\|WP_050351192.1\|3446141_3446819_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.40864e-106
NZ_CP017762.1\|WP_072741928.1\|3439743_3440709_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	3.25136e-108
NZ_CP017762.1\|WP_050351199.1\|3433316_3434384_+\|hypothetical-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0.00177563
NZ_CP017762.1\|WP_072741921.1\|3426927_3427875_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	6.64933e-100
NZ_CP017762.1\|WP_072741933.1\|3449399_3449732_+\|mRNA-degrading-endonuclease	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	4.66006e-34
NZ_CP017762.1\|WP_072741929.1\|3440748_3441870_+\|hypothetical-protein	gnl\|CDD\|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	1.14014e-114
NZ_CP017762.1\|WP_050351201.1\|3432067_3432316_+\|hypothetical-protein	gnl\|CDD\|274963	TIGR04075, Ser/Thr_phosphatase_family_protein, polynucleotide kinase-phosphatase. Members of this protein family are the bacterial polynucleotide kinase-phosphatase (Pnkp) whose genes occur paired with genes for the 3' terminal RNA ribose 2'-O-methyltransferase Hen1. All members of the seed alignment belong to a cassette with the Hen1. The pair acts in bacterial RNA repair. This enzyme performs end-healing reactions on broken RNA, preparing from the RNA ligase to close the break. The working hypothesis is that the combination of Pnkp (RNA repair) and Hen1 (RNA modification) serves to first repair RNA damage from ribotoxins and then perform a modification that prevents the damage from recurring. [Transcription, RNA processing].	0.000278926

>NZ_CP017762.1|WP_072741925.1|3434617_3435346_-|hypothetical-protein
MRNEKIFLSLFILTCLFFVFGFSHPSNAEKAIVNNKEKSIEESYRDATNGISDIDTSKFGVSSEISAISRNLTSEAPIAIEEYSTAQILSETVDDKGNKDQLIAVTVFNDIELKEEGAKIRTLGDKGNEELTPFVRAYNRIYYQNSTDRGVAYAKLTRVTGGWEVFNPLTTLSNRVVRYGSSGWPNGSQATVKYPIGNTYSYKTPSSWKRTALTGSYAIGTNSTVTVKRGSSTWTVKVKTNL
>NZ_CP017762.1|WP_050351199.1|3433316_3434384_+|hypothetical-protein
MRLLNKILGGVALISLVAVFLTSGVNAEEYVKPKFLRAEFAKEAFQAGEPVELTVNSEAGTNEIERVWVQIEHEQTKRLFSSNNVIYSESGTEVKIHLPEEAPSGKYAIQAIIITDSAGVKTNIFNPGASFDLIGESTDTEKAVFQNAVFDKEQYQPGEEVVLKIEATDDESGIDWVFPSIQHLSSEEYTFQGFSEEVNGYHEFRFQLPDNALNGTYGIQYLTIRDHSGNEQDVFDVNATFEVVGGSLDADAPTLKSIAIDKDQYKQGEQVHINIDAEDKSGVKSVFLYVEHKQTGVQYNDFATFNGETFDFNRELPSNAPLGEYEVFAVYLEDNLGNQVSLFNYEPRIEFEVIK
>NZ_CP017762.1|WP_072741924.1|3432422_3432836_+|hypothetical-protein
MSAYDTPTETCPYCGDEMDTDWVDNGIGMVQRGPYHCQKCHASEIGPQLLDWYYKNREGHTIYLPGKRRYNSLLKKKVKWGTTPVLKSGPPFSEDELKTGYYKGKIPPYANTVAGKLVDHQKDKQMYDIGLLDEKKI
>NZ_CP017762.1|WP_050351201.1|3432067_3432316_+|hypothetical-protein
MNWIRNQFIHSTEKAPKTVFFGHTPTGLIHDEKDNYDIWTSEKGDKVDIDGGCAFGGQLDAIKTDKKGNILQKIAIASEMNQ
>NZ_CP017762.1|WP_072741923.1|3430772_3431984_-|hypothetical-protein
MEVHVKVSIPSYNYRGFVARAVCDSKTDWELPESYLAYLEKSHQNKIIYQTKTTEETSKLEFLIQQAHGLYVLIKDHAEVENFRSFEHLARLLKEQSITTKDGSVMPVEGAKLTSQILQNPSDPDATFRHKAGESHIGHSLNFVEVYDNETDMGLIMHADVKENTYSDAQYGEDFVKNHPLAKEMDTLAVDGAYYRQETVKHADELGLEINFSQMTGRAVAEDSIGVDQFKIDPETRKITRCPQGHQPIFSLYDEIKETHTAKFYKEHCQNCPLFERCQVKEQKRAYHISFSENKIRTDQTRSKMGTDRHRKLSNYRAGVEGVPSVLKRAYRLEHLPVRGQVRSNFCLHHRPKLQKMQEIHQKEWSSHFYASYISKKICDQKNFDHKDSTLTFFGNKKLVFGI
>NZ_CP017762.1|WP_072741922.1|3428401_3429514_+|cupin-domain-containing-protein
MAEKASYLHDKDVKDFTKDIQQYNLGPLWEAIPEVMNKNPEPHAQAYLWSSELIEKKLTEAAQIFTPERGGERRAIYFQNPGLTYRKPWGQVSTTQTLYAAVQLLLPGEEAPSHRHTQSALRFITEGEGAYTIVQGERIFMEEGDFLITPKNLWHGHGHLGNKPMIWMDALDIPTVYNIGGTFFEPYEDGLQQPNVPDNFSEKRYRGGMVRPVGDDKYDVAPLANYKWSRTVDAIKGLMEFDPDPNYGFAVDYMNPTTGKSANPTMGTRMQFLPKEFNTKSLRHTHSTIYHAYKGSGYTIINGVRFDWKAGDYFVVPNWAWYEHVPAEDSYLFSVNDIPIMDRFELERVEQYERNNGHQTVTGEFKPDFR
>NZ_CP017762.1|WP_050351205.1|3427876_3428383_+|DinB-family-protein
MASTKVEGYVESIHQSLDNILSIVSYLSEDMIRWKPSRDEWSILQILSHVGESTLFWLDEMDRVLEKPGTEWGRGLGHSGRLAAVEAPDKLTIDDAIAKVNGLKEEVTNRLSKVSEDRLTEENPHRNFGKFGNKPISFLIEHFLVEHVEGHYNQIQRNLTKLSEETIK
>NZ_CP017762.1|WP_072741921.1|3426927_3427875_+|fumarylacetoacetate-hydrolase-family-protein
MKLITYKANGYVRIGAFIDEDTIIDLNYAYQAQLQSEGKYRYREIAEAFVPPAMEAFLQGGKESLEIAKKATNFALEIPAYQHKLVYKKEEIKVEAPLNKPGKMICVGHNYREHILEMGRELPSHPVVFSKFANTIIGPEDDIPYYPLSEQLDYEAEFAFVVGKQARNVLEEDALDYVAGYTIVNDVTYRDIQRRTLQWLQGKAVDGSAPMGPWLVTSDELTDPSGLEMVLTVNGEERQRSNTKNLVFTVQKLVTFLSNLMTLEPGDIVLTGTPGGVGVARDPQVFLKDGDVVTIEVDRIGVLKNKVALQQGGDV
>NZ_CP017762.1|WP_156875353.1|3426746_3426914_+|hypothetical-protein
MTNGVVRVLLNKEVLYISMETWRAIDYIYAIIISYKVQIRILEGIMLSAWNEPYF
>NZ_CP017762.1|WP_050351207.1|3426207_3426750_+|hypothetical-protein
MSVVFQEDTSKMTVNQAFEKLTTLGWFKEGGRVEKEIETLMEQFLKQFNIKQYEMKWLHKEELIEVIERFSFQGSDIWNELKEIPDHLKQQISANNDDSYLERLVDILPEAVFHPAFDGAFKQYSEEKTIRFLTGNAMYFALLICIAELASKGDLFQPIFQIIERGHVPVGIEGNMIYLL
>NZ_CP017762.1|WP_050351196.1|3439352_3439622_+|30S-ribosomal-protein-S14
MAKKSKIAKEKKRQKMVEQYATLRKELKAKGDYEAIRKLPRDSSPTRLKNRCEVTGRPRGYMRKFNMSRIAFREYAHKGQIPGVKKASW
>NZ_CP017762.1|WP_072741928.1|3439743_3440709_+|GTP-binding-protein
MSQKQTIPVTILTGFLGAGKTTLLNNLLKDMPKQKIAVIINEFGDTSIDSHLVVSTREEIIEINSGCICCNVRGDLINILSNLIAQEEKIDRVIIETTGMANPAPVIQTFLMDEKTGKSFEIDSVITMVDAQHIWLHLKEEEPGKQIAFADILLINKMDLITANEKIKLEQQLVNMNPHAKRVYTTYANVNIQDLIGKKSFDLGNLLKIDPKLLVETHHHHHNDQVTSFVFREGRPLDLEKVNRWFAYLVHFKGENLYRYKGVLHINHLEKRVVFQGVHMLFAGTEGTEWADNEPRQSEIVFIGKHLDYQELAKGFQYCLA
>NZ_CP017762.1|WP_072741929.1|3440748_3441870_+|hypothetical-protein
MITVNKIYDVVIVGAGPSGIGVATLLQQMNCTSYLILEKEEVGASFLRWPEEMRFITPSFPAQGFGQTDLNAIVPKTSPAYTLNMEHPTGEAYAEYLDVVADHFALPIKKGVQVKQIHKKDGIFTIDTTQGIYQSRYVVWAAGQYQYPNLRPFPGAELGVHNSLIPSWRELEGDDFIIIGGYESGMDAAFHLGRFGKKTTIIAKTNTWELDNSDPSIALSTYTYSRVCHLLGSDLLTVVGNTAVTRIEAVSSGYDVYTSSGKVYFTTEKPILATGFIGSTTKIENLVTRGQYDEVLVNEIDESVATSGLFLAGPELRHKDHIFCFIYKFRQRFAIIAETIGYRLNLDLSILEQYQQENFYLKDLSMCGERCQC
>NZ_CP017762.1|WP_072741930.1|3443646_3446145_-|ABC-transporter-permease
MIRVKNKKIIRKLARRNFRSSKVRNVFAVMAIALTTLLFTSLFTLGSGMIKSTQRADMVMSGGDGHARIENMTESEYRTIERHPLIQEMSYIRKLADSVDNAALTKRQTDFWYYDDLQLKYLFIELTSGHKPQEEKEIITDTKTLELLGIPQKLGTPLTLELTINNDKVIREFVLAGWWESHPGVPVGTIISSRAYMDAHLGELESTYRQDQSKTGSITGNLKFANSKNINEKLETVLIDSGFSMNINSQNYLNAGTNPIYLSKSTSAGFGTILLLSSILVLFMLTGYLIIFNIFQISVMRDIRFYGLLKTVGTTGRQLRAIIRRQAWGLSLVGIPLGLFGGFFVGRSMVPTLIEQSQLAGSKAVVSANPLIFVAAIMFTLATVFISIRKPLKMAAKISPVEAVSYTNTNSVSRKKKTKKSSNSGTPRRMALNNLGRNKKHTVLVILSLSLSIVLTNTIFNFSQSVDVDKALQNASDSDFRIGHIDLFNYKYKGKEESALSESLIAAVEKQEGFETGGRQYGSPATYKSETTRQTVNQRLDGSFSTNLIGLDEFSFSRLELLDGELDREKLANGKYILEGVWSDTRGNLDESSMNHSVGDQVKLNYGGNTIEVTVIGHIIANETNTYDWVGSGFFLPGEMYKKLTGNTHAMSYVFDVAEDEEGDMERFLKWYTNSIEPSMNYKSKLTVTAGLTDIQDTIMLIGGTLALIIGIIGVLNFINIILTSVLIRRREFAVLRSIGMTKQQLLKMLCFEGGYYAAWTVAVSILLSIGSSLLIVRPLSAQIWFLTFHFNFWPLVIILPLIFVIGILIPYIIYHATKQQSIVEQLRIEGY
>NZ_CP017762.1|WP_050351192.1|3446141_3446819_-|ABC-transporter-ATP-binding-protein
MTILKTMNLKKIYTNGATSVHALNNVNLSVERGEFVAVVGTSGSGKSTLLHMLGGLDRPTSGTVTVDGKDIFSLKEEALTIFRRRKVGFVFQSFNLVPILNVYENIVLPIQLDGNKPDKSYVNQIIQTLGLDDKLQRLPSQLSGGQQQRVAIARALATKPIIVLADEPTGNLDSKTSQDVIGLLKVTGEKFSQTIVLITHNEEHAQLADRIIRIEDGKILGGDRV
>NZ_CP017762.1|WP_156875354.1|3446926_3447847_-|sensor-histidine-kinase
MSQWLIMFGIAVVTGIAFAIPVILLYRRRMRQLLSSMDDMLNSAIDDDFSEGCFDESALSAVETKLARFLAFCAVSSKNLTNEKENIESLISDISHQTKTAVANILLYTQLLEEERLPQDCVEYVNTLSAQAKKLDFLIQALVKTSRLESGIITVQPQRDSVQKLLERAITQVSPRAKEKEITIQLESTDGIAYYDPKWTIEAVYNVLDNAVKYSPMQGSIKIKTIPYELFFRIDITDQGIGITEDEQSKIFTRFYRSSATNVQEGMGLGLFLAREILSTGGGYIKVASKLGQGSTFSIFLAAGEK
>NZ_CP017762.1|WP_072742457.1|3447846_3448533_-|response-regulator-transcription-factor
MMTIIKILIIEDDLSLSNGVAIALKNSEFTIIQARDLNSARMEIQKTTFDLIILDINLPDGSGLDFLKELRKFSAIPVIMLTAKDMETDVVTGFEFGADDYITKPFSLMILRARVRAQLRKVSAISIEPIQIDGFSFSFTKMEFSKYGVPIELSKTEQKLLRCLLENKGHTMERSQLIDIIWTDGADYVDENALSVTVKRLRDKLEDIPSSPKYIKTVYGIGYTWAVT
>NZ_CP017762.1|WP_050353472.1|3449148_3449400_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MTATATVSKWGNSLGVRIPKDMADSANINQGTEMTITLDQKGQIILTPIKNKKEYSLDELLNQCKPEHRHQEIDFGIKGEELI
>NZ_CP017762.1|WP_072741933.1|3449399_3449732_+|mRNA-degrading-endonuclease
MVAPERGDLVYVDFDAQSGREQAGIRPAIVLSPKQFNQITGFTVLCPITKTVRGWGYEVALPDGLAVSGVILTDKVKSVDWNTRKLKIKGQAPEEIVEDCLAKIHTFLGQ
>NZ_CP017762.1|WP_083547292.1|3449797_3450187_+|hypothetical-protein
MTDSLTAETPPEELSGGDYQKGVVTYVVDGDTFDVKLENGKTERIRPILVNAPEICHKSSPSDCEAEPYGDEAADFTKDLLEGETVYLEQDVSERDPYDRLLAYVYLENGQMYQELILSEGLAEVSVTP

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Crispr_ID: NZ_CP017762_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017762_8

3467608-3467972

Orphan

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCTATATAAGGTGCGAC	PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CRT

5 spacers

The CRISPR arrays of NZ_CP017762_8

>merge|NZ_CP017762|8|3467608-3467972|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATCCACGCACCTATATAAGGTGCGACCTAATGGGGCATAGGTAAACTCATCTACTCCCGTAATTTCAATCCACGCACCTATATAAGGTGCGACGACGACAACAGAAATCCTTTATATTGGAACACGAATTTCAATCCACGCACCTATATAAGGTGCGACGTGGTAAGGAGGGTTAGCCTACACCACATTAGGATTTCAATCCACGCACCTATATAAGGTGCGACGGGTTGTTGTGGACAACGGCAAAAGATCCAAATAAATTTCAATCCACGAACCTATATAAGGTGCGACGGCAAAGCAGGATAATCCTAGTAATTCATGGTTCTAATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|8|7|3467608-3467972|PILER-CR
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CTAATGGGGCATAGGTAAACTCATCTACTCCCGTA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GACGACAACAGAAATCCTTTATATTGGAACACGA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GTGGTAAGGAGGGTTAGCCTACACCACATTAGG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GGGTTGTTGTGGACAACGGCAAAAGATCCAAATAA
ATTTCAATCCACGAACCTATATAAGGTGCGAC	GGCAAAGCAGGATAATCCTAGTAATTCATGGTTCTA
ATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|8|8|3467608-3467972|CRISPRCasFinder
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CTAATGGGGCATAGGTAAACTCATCTACTCCCGTA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GACGACAACAGAAATCCTTTATATTGGAACACGA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GTGGTAAGGAGGGTTAGCCTACACCACATTAGG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GGGTTGTTGTGGACAACGGCAAAAGATCCAAATAA
ATTTCAATCCACGAACCTATATAAGGTGCGAC	GGCAAAGCAGGATAATCCTAGTAATTCATGGTTCTA
ATTTCAATCCACGCACCTATATAAGGTGCGAC

>NZ_CP017762|8|7|3467608-3467972|CRT
ATTTCAATCCACGCACCTATATAAGGTGCGAC	CTAATGGGGCATAGGTAAACTCATCTACTCCCGTA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GACGACAACAGAAATCCTTTATATTGGAACACGA
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GTGGTAAGGAGGGTTAGCCTACACCACATTAGG
ATTTCAATCCACGCACCTATATAAGGTGCGAC	GGGTTGTTGTGGACAACGGCAAAAGATCCAAATAA
ATTTCAATCCACGAACCTATATAAGGTGCGAC	GGCAAAGCAGGATAATCCTAGTAATTCATGGTTCTA
ATTTCAATCCACGCACCTATATAAGGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017762.1\|WP_072741948.1\|3473550_3474462_+\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|223406
NZ_CP017762.1\|WP_072741949.1\|3474467_3475421_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|238571
NZ_CP017762.1\|WP_050351922.1\|3471079_3472351_+\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NZ_CP017762.1\|WP_072741940.1\|3462238_3464437_+\|DUF1906-domain-containing-protein	unknown	unknown	gnl\|CDD\|119380
NZ_CP017762.1\|WP_072741947.1\|3469511_3470534_+\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270397
NZ_CP017762.1\|WP_072741945.1\|3468204_3468579_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP017762.1\|WP_072741944.1\|3466423_3466819_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050351921.1\|3470572_3471058_+\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NZ_CP017762.1\|WP_050351925.1\|3476004_3477333_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226987
NZ_CP017762.1\|WP_072741941.1\|3464470_3464983_-\|YcxB-family-protein	unknown	unknown	gnl\|CDD\|379553
NZ_CP017762.1\|WP_050351909.1\|3460539_3460797_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|224937
NZ_CP017762.1\|WP_072741943.1\|3465839_3466349_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741946.1\|3468858_3469245_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP017762.1\|WP_082240932.1\|3458894_3459353_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214615
NZ_CP017762.1\|WP_050351916.1\|3467049_3467472_+\|dCTP-deaminase	unknown	unknown	gnl\|CDD\|274062
NZ_CP017762.1\|WP_082240933.1\|3478178_3478898_+\|DUF4176-domain-containing-protein	unknown	unknown	gnl\|CDD\|379364
NZ_CP017762.1\|WP_050351923.1\|3472368_3473331_+\|C-terminal-binding-protein	unknown	unknown	gnl\|CDD\|240624
NZ_CP017762.1\|WP_156875357.1\|3460065_3460230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_072741942.1\|3465510_3465825_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017762.1\|WP_050351908.1\|3460321_3460537_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP017762.1\|WP_072741948.1\|3473550_3474462_+\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|223406	COG0329, DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane].	5.00406e-93
NZ_CP017762.1\|WP_072741949.1\|3474467_3475421_+\|sugar-kinase	gnl\|CDD\|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	2.21145e-107
NZ_CP017762.1\|WP_050351922.1\|3471079_3472351_+\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	1.33025e-125
NZ_CP017762.1\|WP_050351921.1\|3470572_3471058_+\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	1.8051e-39
NZ_CP017762.1\|WP_072741947.1\|3469511_3470534_+\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270397	cd13679, PBP2_TRAP_YiaO_like, Substrate-binding domain of 2,3-diketo-L-gulonate-binding Tripartite ATP-independent Periplasmic transport system and related proteins; the type 2 periplasmic-binding protein fold. This subfamily includes the solute receptor protein YiaO of TRAP transport system. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.04795e-151
NZ_CP017762.1\|WP_072741945.1\|3468204_3468579_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.34094e-13
NZ_CP017762.1\|WP_050351925.1\|3476004_3477333_-\|hypothetical-protein	gnl\|CDD\|226987	COG4640, COG4640, Predicted membrane protein [Function unknown].	1.6553e-05
NZ_CP017762.1\|WP_072741941.1\|3464470_3464983_-\|YcxB-family-protein	gnl\|CDD\|379553	pfam14317, YcxB, YcxB-like protein. The YcxB-like protein family includes the B. subtilis YcxB protein, which is a functionally uncharacterized transmembrane protein. This family of proteins is found in bacteria, and is approximately 60 amino acids in length.	0.00456257
NZ_CP017762.1\|WP_050351909.1\|3460539_3460797_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	3.1548e-09
NZ_CP017762.1\|WP_072741946.1\|3468858_3469245_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.20845e-16
NZ_CP017762.1\|WP_082240932.1\|3458894_3459353_+\|hypothetical-protein	gnl\|CDD\|214615	smart00318, SNc, Staphylococcal nuclease homologues.	4.47717e-29
NZ_CP017762.1\|WP_082240933.1\|3478178_3478898_+\|DUF4176-domain-containing-protein	gnl\|CDD\|379364	pfam13780, DUF4176, Domain of unknown function (DUF4176).	1.75774e-14
NZ_CP017762.1\|WP_050351923.1\|3472368_3473331_+\|C-terminal-binding-protein	gnl\|CDD\|240624	cd05299, CtBP_dh, C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor. The transcriptional corepressor CtBP is a dehydrogenase with sequence and structural similarity to the d2-hydroxyacid dehydrogenase family. CtBP was initially identified as a protein that bound the PXDLS sequence at the adenovirus E1A C terminus, causing the loss of CR-1-mediated transactivation. CtBP binds NAD(H) within a deep cleft, undergoes a conformational change upon NAD binding, and has NAD-dependent dehydrogenase activity.	2.13842e-166
NZ_CP017762.1\|WP_072741940.1\|3462238_3464437_+\|DUF1906-domain-containing-protein	gnl\|CDD\|119380	cd06418, GH25_BacA-like, BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of Bacillus subtilis. BacA has a C-terminal catalytic glycosyl hydrolase family 25 (GH25) domain and an N-terminal peptidoglycan-binding domain comprised of three alpha helices which is similar to a domain found in matrixins.	1.25868e-69
NZ_CP017762.1\|WP_050351916.1\|3467049_3467472_+\|dCTP-deaminase	gnl\|CDD\|274062	TIGR02274, Probable_deoxycytidine_triphosphate_deaminase, deoxycytidine triphosphate deaminase. Members of this family include the Escherichia coli monofunctional deoxycytidine triphosphate deaminase (dCTP deaminase) and a Methanocaldococcus jannaschii bifunctional dCTP deaminase (3.5.4.13)/dUTP diphosphatase (EC 3.6.1.23), which has the EC number 3.5.4.30 for the overall operation. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	3.80284e-47

>NZ_CP017762.1|WP_050351916.1|3467049_3467472_+|dCTP-deaminase
MLETPEDGGPPASYHEMQVTDEKVVTIPPNTFMLGTTLEQIRLPNDLTAFVEGRSSIGRFGVFIQNTGWIDPGFSGQITLELFNANRVPVQLKVGMRVCQLVIVQVDQATEGYSGKYLFQEGATPSRAYMDHDRGGKINE
>NZ_CP017762.1|WP_072741944.1|3466423_3466819_-|hypothetical-protein
MSNAIRFAVGNLSQGDVVILHGAEQLAPGIKQYVRDRFDQLYDNGVRVVHIYNSVDRMIADRAFNQFESADYTLLGGMTKATIAEYEDALKQEVPIALKTLLEHKERYRYYLRRGFDNVVFASDIQMGFTK
>NZ_CP017762.1|WP_072741943.1|3465839_3466349_-|hypothetical-protein
MYNEEGYFLPHLLYGEKIKGQLQSSPLELKNSGVHDFHIRIQTELMHQLAMEMEESEELITSTRIALTRLLDDHLATMKELRNTYRNRVGSGKYDKLNTAHVDEIFRELVDVESDGTPLLIDINEFEHLLEKLRKSQHDTGEIAYNMEKMSKDFKQMDQILAQWLQIRQ
>NZ_CP017762.1|WP_072741942.1|3465510_3465825_-|hypothetical-protein
MSSMSDWWKDYLETNAQKEALKKKIKLDLEENVDITKLHFEHSYAVGLLSQKHQNILTKVNQHFDGKASHALMNRFIENIIQLQEMDRVYKANYEHVKLKHGFW
>NZ_CP017762.1|WP_072741941.1|3464470_3464983_-|YcxB-family-protein
MIAKFNITDKDLIAQQKNAIKTTKFHRKSRIMQLVISFLGIVLMLIIINATIPSIIFCLFLYFILTPFIWRSYEYLYIRRYKRDILRHNKNKIGPFTLNLSEEKLVKESQHLTEKIQWNELNRFKEDQERYFLYFTDLNAITIKKEPDNMNEQEIKEYQAFIKRKVKKKK
>NZ_CP017762.1|WP_072741940.1|3462238_3464437_+|DUF1906-domain-containing-protein
MDKMVLEVQKWLNKTYKGKNGYTTIPENGKTGNTTVKALIIGLQIELGITKPVPSFGPETARRFPGLARQGKDEKPNNLIKILQGGFWCKGYNPGGFSGNFFEDTEKEVKDFESDVGIEPTGFVDSKLMKAILNTDGFVLNNSSGRSHNREIQQSLNREYSQYFDYIPTNGVYERKTNKALIYALQHEEGIGHIANGNFGPATIDNCPTLKKGDAPANFTRILQWALACNMPIYDTHPYDGDFDHDVELAVITFQDFMTLPETGIADMPTIKQLLTSNGYTGRPAIACDASTVIDYKTVKTLRDYNYQIIGRYLTGNVATDAGLRSKAMTHEELSILAINGIRVFPIYQDGGYEHEYFVQGRGREDAWKAIRAANELGFPSGTTIYFAVDYDAYGFQVENNIIPYLEEVRSVLDIAKEKDLPEYKLGVYGSRNTCIQAQGGKVSADYSFVGNMSTGYSGNLGFPMPQNWSFNQFYETTIGLGGPGMLGIDKNDYSGRDPGVAAVNPPDTSEVSKEYRAKHDAFIEIGKNIPGLQEFNPELFATNINFSSTHRAFSIGNIVTVDVEFSEQLNPPTEGGTTTTLQITPDGVSGSLESLLGENIAQFTQNRLGFYEDFIDNMATSIGAGAIQMTLKGTGTSAELRVTAFKEEIPVDGGGNVQLAVTVIFTVDIDLTDASESFSTDVAKAAGLTLGIIFVISLAVTYGIPAMTALAASIIIALLIGEQDDIDDGQS
>NZ_CP017762.1|WP_050351909.1|3460539_3460797_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MYDIIFSKQAKKFIDKQDKVTKKRLRNAMLELSENPYRAKDVKKLKGDKAYRKRVANFRIIFDIIDQKLVVNVLKVDNRGQVYRK
>NZ_CP017762.1|WP_050351908.1|3460321_3460537_+|hypothetical-protein
MSHIFDHNREMLHKLIDDLPEDKLPKAADLFEKMIGEETVSDEDKKELEIARKEIENGESYSFDEVFGELD
>NZ_CP017762.1|WP_156875357.1|3460065_3460230_+|hypothetical-protein
MQKDTYVRVVKKAVFKEKLLAYMQKRLKKGTFRAKKEHFDPKKEQSRNKVFSVA
>NZ_CP017762.1|WP_082240932.1|3458894_3459353_+|hypothetical-protein
MTDSLTAETPPEELSGGDYQKGVVTYVVDGDTFDVKLENGKTERIRPILVNAPEICHKSSPSACEAEPYGDEAADFTKDLLEGETVYLEQDVSERDPYDRLLAYVYLENGQMYQELILSEGLVEVSVYEPDIKYQSHLEKIEQKINKSTTHH
>NZ_CP017762.1|WP_072741945.1|3468204_3468579_-|helix-turn-helix-domain-containing-protein
MYSFSERLTDVRVENGFGQKDIAEKLNITTSAYGYYEQGKNEPSIETIRTLAKLFDVSTDYLLGLIDQPKHPINFTIKDDFTLTESELQTVKQMKEQQLLSELSENPVENVEKLTKLWKFINEL
>NZ_CP017762.1|WP_072741946.1|3468858_3469245_-|helix-turn-helix-transcriptional-regulator
MCSFSERLIDLRVEAGYSQKEIAAMLNMTASAYGYYEQGKNEPSISTLKKIATIYNVSTDYLVGTIDTPTHQINFFITEHFSLTESELTVVKQMKEKQLLAEMEDNPTVNVDKLVRFWTFLTKEMNSG
>NZ_CP017762.1|WP_072741947.1|3469511_3470534_+|TRAP-transporter-substrate-binding-protein
MRKKSVLVILFLVLITLTSCKQASGSAVEETEKTILAGIGYNNQHSQYKGLERFKEIVEKKSKGALNVKIFHSGQLGDDRSMIESLQLGVLQVTIPSTAPLANFISEFLIFDYPFLFPNEEVADEVLDGEMGKRLLDLLPQQNLIGLAYWENGFRDLTNSTRPVSSMQDLKGLKVRTMESELHLSAFRKLGANPTPMAFGELFTAMQQGTVDGQENPISTIYLEGFYEVQKYISNTHHVYTPFIFLMSKPFYESLNEKEQKVVSEAAREAGKYQRKLNRKDTENYLQKLKDNGMEYTEITESSRKEMKKTIEPLLEQYTKEIGTDMVSDVYNAIENAQSP
>NZ_CP017762.1|WP_050351921.1|3470572_3471058_+|TRAP-transporter-small-permease
MKVIRCLDKHIEEYLLVILSATMVLVIFLQVVMRYVLGSSLSWSEELARYCFIWSVYIGISYGVKRKRHISVDVLLVMLKERGRLILTILTNCLFIIFATIIIYYGADITIRLLSWGQDSPALQIPMGVVYLAAPVGLGLCIIRLMQDILFTAEKLKNKIT
>NZ_CP017762.1|WP_050351922.1|3471079_3472351_+|TRAP-transporter-large-permease
MTATILFTSFALFLLLSVPIGISIGLSTLVTIALIDILPVSFLAKEFVTSVDSFPLMAVPFFILAGEIMGKGGISHRLVNVATSIVGNKTGGLAIAGIITSLFFAAISGSGPATVAAVGGMMIPAMVDHGYDKRFATAVIASAGALGVIIPPSIPMVIYGVIGSASIGDLFISGVIPGVLVAFGLMVWSYIYAKKMGYTGTDEKMSIKKIGESLYDAKWALLIPIIILGGIYGGIFTPTEAAVVAVVYSFMAGIFLYREIKLQDLPRLFADGALTTATILIIVGAATAFGRLLTIEEIPTQVADIMLSITDERIILVFLIITLLLIVGCFMDTLAAIIILTPILLPIAINLNFDPIHFGIIMVTSLAIGFITPPLGVNLFVSSGISGLSISVLSRAIVPFFIAMVITLLIITFIPQLSLILIN
>NZ_CP017762.1|WP_050351923.1|3472368_3473331_+|C-terminal-binding-protein
MKRFKVLISDYEFKSITIEKEVLHSAGAEIITAQCKTEDEVISAGKGVHAIINQYAPITRKVMESLPNLKVIARYGVGVNTIDLEAATKHGIYVTNVTDYCMEEVADHTFSLLLACARKIVQLNKAVKNDVWDYKVGMPIYRLKGRILGLVGFGSIPQNLAKKAISFGLKLVIYDPFISKSLADKYKAEVVSLNELMKISDFISVHTPLTNETKGLIGKEQFNHAKKEAFMINTSRGEVVDEEALIHALRKNQIGGAALDVVSQEPIRHNHPLLKMENVILTPHVAWYSEESQIELQRKTAENVVDVLKGSSPKYLVNKI
>NZ_CP017762.1|WP_072741948.1|3473550_3474462_+|dihydrodipicolinate-synthase-family-protein
MAVKFKGVIPPVSIMFDQQGKFDPGSMEKVIDFLIDSNVDGLFFLGSGGEFTQLSSTERKEIAEFVIQYVDKRLPILIGTGSTNTREVIELSRHAFNQNADGVVVINPYYWELSEENLYLHYHEIANAVEGPILLYNFPALTGQSIPPHVVLRLVKKHEHIVGIKETIDSTAHIRDMITTVKAEYPDFSVLAGFDDHLFNTLALGGDGAISASVNFAPQLSVDLYQAFRTGNYKTAMELHQKLAQIPTLYQLEIPFISVIKEATKMCSLDIPTYVQPPARMVSEKKREQIRNVLRQIGLIEKR
>NZ_CP017762.1|WP_072741949.1|3474467_3475421_+|sugar-kinase
MDVITIGETMVLFDPVFDGPIRYVDTFRKRIGGAESNVAIGLARLNKKVGWISQLGEDALGDYVQAFIRGENVDTSRVVRTNKAQTGVYVKERVREGHTSVYYYRKGSAASLLTMENIDWEYIKQAKIIHITGITPLLSESCWEVSKQLFSFAKQNGIMTSFDPNIRKKLWDNPVIAKERLLYLAEQSDILLSGLNEAVTLLNTDDINEILAYFRHKNVGSVVLKDDANGVHYATDGGEGGFIPSYKVERVVDPVGAGDGFAAGVLAALLDKQPLEEAVRLGAVIGAMVVSTYGDVEGLPDKQTIEQFMYGKHDVIR
>NZ_CP017762.1|WP_050351925.1|3476004_3477333_-|hypothetical-protein
MKQHILMKSAFLLFLFTLVLVLSGCTQSPEKTLEELKQAVEDRDYITFYELVDKDDDVYWTEKQAQSMIEDFHDNREDYAVQLELLQQQAMALKEDNPLINEEGMLYFNKDEQLKVRTYAVTAEEGLLDGVEKLSVKIDDEKELNIDANKNDTLKLGLFGPGEYSFEAAAEYPYADVKNKGEFYVSGVSDFNQAVELGLEGKYIGIASHIPDTKLFINGKDANVNISELDGGEMNDESLFGSTLLDHNFGPISEGISLQGVAKMPWGKIKSEEVKITSDTKSYDLSPKILQDKKAQKKVTELINNYQKDKMTALVNLDDKHLKNLSNSFKKSLSKEIIQAKEQERTYAGQVLGTRIDYSKALYEEGEGGRHYVTIPIELHRTYVERYFFNKDEEPTEEYEHQEIKLEYISDKEEWIIDQEDSYYGADEDDYMKSEEVVETEF
>NZ_CP017762.1|WP_082240933.1|3478178_3478898_+|DUF4176-domain-containing-protein
MRIFMTERMQKQLVSLALKKVDQLIQSYSTDLDLQVGQNVREFFQLCLREEKMLYDIFSTLKRKQTNADIEWNHGIVSVNQKEGYCTITYVNKQFSLQHDRLFELLANTIEIMREVLPLGTIVELDPTYFKPDKNNTSPSKVVITGRFVSPKNYQSYFPYVGILYPVGEIKAGAKINFTAPLIKRVIHRGYQDEMEEAFVFLMKQEFIVEKDLNSIEFSEHDMSKLQQEMDMELKVGDV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NZ_CP012100	Bacillus thuringiensis strain HS18-1 plasmid pHS18-1, complete sequence	96571-96599	5	0.828
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NZ_CP045607	Bacillus cereus strain SB1 plasmid p1, complete sequence	285370-285398	5	0.828
NZ_CP017762_4	4.5\|3361843\|33\|NZ_CP017762\|PILER-CR	3361843-3361875	33	KJ210330	Staphylococcus phage GRCS, complete genome	13958-13990	5	0.848
NZ_CP017762_4	4.5\|3361843\|33\|NZ_CP017762\|PILER-CR	3361843-3361875	33	MG766219	Staphylococcus phage vB_SauP_phiAGO1.9, complete genome	13714-13746	5	0.848
NZ_CP017762_4	4.5\|3361843\|33\|NZ_CP017762\|PILER-CR	3361843-3361875	33	MG766218	Staphylococcus phage vB_SauP_phiAGO1.3, complete genome	13715-13747	5	0.848
NZ_CP017762_4	4.6\|3361908\|33\|NZ_CP017762\|PILER-CR	3361908-3361940	33	KJ210330	Staphylococcus phage GRCS, complete genome	13958-13990	5	0.848
NZ_CP017762_4	4.6\|3361908\|33\|NZ_CP017762\|PILER-CR	3361908-3361940	33	MG766219	Staphylococcus phage vB_SauP_phiAGO1.9, complete genome	13714-13746	5	0.848
NZ_CP017762_4	4.6\|3361908\|33\|NZ_CP017762\|PILER-CR	3361908-3361940	33	MG766218	Staphylococcus phage vB_SauP_phiAGO1.3, complete genome	13715-13747	5	0.848
NZ_CP017762_4	4.11\|3361835\|33\|NZ_CP017762\|CRISPRCasFinder,CRT	3361835-3361867	33	KJ210330	Staphylococcus phage GRCS, complete genome	13958-13990	5	0.848
NZ_CP017762_4	4.11\|3361835\|33\|NZ_CP017762\|CRISPRCasFinder,CRT	3361835-3361867	33	MG766219	Staphylococcus phage vB_SauP_phiAGO1.9, complete genome	13714-13746	5	0.848
NZ_CP017762_4	4.11\|3361835\|33\|NZ_CP017762\|CRISPRCasFinder,CRT	3361835-3361867	33	MG766218	Staphylococcus phage vB_SauP_phiAGO1.3, complete genome	13715-13747	5	0.848
NZ_CP017762_4	4.12\|3361900\|33\|NZ_CP017762\|CRISPRCasFinder,CRT	3361900-3361932	33	KJ210330	Staphylococcus phage GRCS, complete genome	13958-13990	5	0.848
NZ_CP017762_4	4.12\|3361900\|33\|NZ_CP017762\|CRISPRCasFinder,CRT	3361900-3361932	33	MG766219	Staphylococcus phage vB_SauP_phiAGO1.9, complete genome	13714-13746	5	0.848
NZ_CP017762_4	4.12\|3361900\|33\|NZ_CP017762\|CRISPRCasFinder,CRT	3361900-3361932	33	MG766218	Staphylococcus phage vB_SauP_phiAGO1.3, complete genome	13715-13747	5	0.848
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	MF974398	Leptospira mayottensis 200901116 plasmid p2_L200901116, complete sequence	24742-24770	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	182186-182214	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NC_008012	Lawsonia intracellularis PHE/MN1-00 plasmid 1, complete sequence	26460-26488	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NZ_CP011154	Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence	27339-27367	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NZ_CP011152	Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence	519548-519576	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NC_020128	Lawsonia intracellularis N343 plasmid 1, complete sequence	26507-26535	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	CP020755	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence	136877-136905	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NC_020385	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence	82660-82688	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NZ_CP021062	Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence	352201-352229	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NZ_CP030149	Leptospira mayottensis strain MDI272 plasmid p_Lmay_MDI272_tenre, complete sequence	18598-18626	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	KJ081346	Bacillus phage BCP8-2, complete genome	93096-93124	6	0.793
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NC_027352	Bacillus phage JBP901, complete genome	55079-55107	6	0.793
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	MN692986	Marine virus AFVG_117M62, complete genome	36104-36137	6	0.824
NZ_CP017762_2	2.1\|2181081\|29\|NZ_CP017762\|PILER-CR	2181081-2181109	29	NZ_CP043858	Arcobacter cibarius strain H743 plasmid pACIB, complete sequence	62161-62189	7	0.759
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NC_011775	Bacillus cereus G9842 plasmid pG9842_209, complete sequence	78555-78583	7	0.759
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	NC_042140	Bacillus virus BM15, complete genome	131539-131567	7	0.759
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	MH638309	Bacillus phage Hobo, complete genome	131539-131567	7	0.759
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP045607	Bacillus cereus strain SB1 plasmid p1, complete sequence	285370-285401	7	0.781
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	KJ081346	Bacillus phage BCP8-2, complete genome	93096-93127	7	0.781
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NC_027352	Bacillus phage JBP901, complete genome	55079-55110	7	0.781
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	NZ_CP014200	Escherichia coli strain MRE600 plasmid pMRE600-2, complete sequence	33830-33863	7	0.794
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	NZ_CP013139	Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence	885727-885760	7	0.794
NZ_CP017762_1	1.3\|2171898\|34\|NZ_CP017762\|PILER-CR,CRT	2171898-2171931	34	NC_018492	Bacillus cereus FRI-35 plasmid p01, complete sequence	71825-71858	8	0.765
NZ_CP017762_1	1.3\|2171898\|34\|NZ_CP017762\|PILER-CR,CRT	2171898-2171931	34	NZ_CP027420	Staphylococcus cohnii strain FDAARGOS_334 plasmid unnamed1, complete sequence	10312-10345	8	0.765
NZ_CP017762_1	1.3\|2171898\|34\|NZ_CP017762\|PILER-CR,CRT	2171898-2171931	34	KM983333	Clostridium phage phiCTC2A, complete genome	3513-3546	8	0.765
NZ_CP017762_1	1.3\|2171898\|34\|NZ_CP017762\|PILER-CR,CRT	2171898-2171931	34	KM983330	Clostridium phage phiCT19406A, complete genome	3513-3546	8	0.765
NZ_CP017762_1	1.6\|2171897\|35\|NZ_CP017762\|CRISPRCasFinder	2171897-2171931	35	KM983333	Clostridium phage phiCTC2A, complete genome	3512-3546	8	0.771
NZ_CP017762_1	1.6\|2171897\|35\|NZ_CP017762\|CRISPRCasFinder	2171897-2171931	35	KM983330	Clostridium phage phiCT19406A, complete genome	3512-3546	8	0.771
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	HQ332137	Prochlorococcus phage P-SSP3 genomic sequence	39644-39672	8	0.724
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	GU071107	Cyanophage P-SSP2, complete genome	12987-13015	8	0.724
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	MH319731	Marine virus AG-345-E02 Ga0172268_11 genomic sequence	85122-85150	8	0.724
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	JX094431	Bacillus cereus bacteriophage vB_BceM_Bc431v3, complete genome	52744-52772	8	0.724
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	MG602477	Bacillus phage BCP01, complete genome	124230-124258	8	0.724
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	KX495186	Bacillus phage PK16, complete genome	54092-54120	8	0.724
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP016845	Carnobacterium maltaromaticum strain TMW 2.1581 plasmid pL21581-1, complete sequence	50911-50942	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP012100	Bacillus thuringiensis strain HS18-1 plasmid pHS18-1, complete sequence	96571-96602	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	182183-182214	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP011154	Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence	27336-27367	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP011152	Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence	519548-519579	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	CP020755	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence	136874-136905	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NC_020385	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence	82660-82691	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP021062	Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence	352198-352229	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	JX094431	Bacillus cereus bacteriophage vB_BceM_Bc431v3, complete genome	52744-52775	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NC_042140	Bacillus virus BM15, complete genome	131536-131567	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	MG602477	Bacillus phage BCP01, complete genome	124227-124258	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	KX495186	Bacillus phage PK16, complete genome	54092-54123	8	0.75
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	MH638309	Bacillus phage Hobo, complete genome	131536-131567	8	0.75
NZ_CP017762_6	6.3\|3429897\|33\|NZ_CP017762\|PILER-CR	3429897-3429929	33	NC_012219	Clostridium botulinum plasmid pC2C203U28 DNA, complete sequence, serotype: type C, strain: (C)-203U28	61240-61272	8	0.758
NZ_CP017762_6	6.3\|3429897\|33\|NZ_CP017762\|PILER-CR	3429897-3429929	33	NZ_CP029459	Clostridium novyi strain 150557 plasmid pCN1, complete sequence	89963-89995	8	0.758
NZ_CP017762_6	6.3\|3429897\|33\|NZ_CP017762\|PILER-CR	3429897-3429929	33	MH051913	Enterobacteria phage vB_EcoM_IME281, complete genome	91380-91412	8	0.758
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	MK250029	Prevotella phage Lak-C1, complete genome	238950-238983	8	0.765
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	3130-3163	8	0.765
NZ_CP017762_6	6.11\|3429894\|33\|NZ_CP017762\|CRISPRCasFinder	3429894-3429926	33	NC_012219	Clostridium botulinum plasmid pC2C203U28 DNA, complete sequence, serotype: type C, strain: (C)-203U28	61240-61272	8	0.758
NZ_CP017762_6	6.11\|3429894\|33\|NZ_CP017762\|CRISPRCasFinder	3429894-3429926	33	NZ_CP029459	Clostridium novyi strain 150557 plasmid pCN1, complete sequence	89963-89995	8	0.758
NZ_CP017762_6	6.11\|3429894\|33\|NZ_CP017762\|CRISPRCasFinder	3429894-3429926	33	MH051913	Enterobacteria phage vB_EcoM_IME281, complete genome	91380-91412	8	0.758
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	NC_031015	Bacillus phage Claudi, complete genome	4529-4562	8	0.765
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	MT777452	Bacillus phage Baseball_field, complete genome	4646-4679	8	0.765
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	NC_049964	Bacillus phage KonjoTrouble, complete genome	4598-4631	8	0.765
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	MN082624	Bacillus phage VioletteMad, complete genome	4598-4631	8	0.765
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	NC_031121	Bacillus phage Aurora, complete genome	4257-4290	8	0.765
NZ_CP017762_1	1.3\|2171898\|34\|NZ_CP017762\|PILER-CR,CRT	2171898-2171931	34	NZ_CP022320	Bacillus altitudinis strain SGAir0031 plasmid pSGAir0031, complete sequence	7265-7298	9	0.735
NZ_CP017762_1	1.3\|2171898\|34\|NZ_CP017762\|PILER-CR,CRT	2171898-2171931	34	NZ_CP018198	Bacillus safensis strain KCTC 12796BP plasmid pBPL056, complete sequence	29017-29050	9	0.735
NZ_CP017762_1	1.6\|2171897\|35\|NZ_CP017762\|CRISPRCasFinder	2171897-2171931	35	NZ_CP022320	Bacillus altitudinis strain SGAir0031 plasmid pSGAir0031, complete sequence	7264-7298	9	0.743
NZ_CP017762_1	1.6\|2171897\|35\|NZ_CP017762\|CRISPRCasFinder	2171897-2171931	35	NC_018492	Bacillus cereus FRI-35 plasmid p01, complete sequence	71824-71858	9	0.743
NZ_CP017762_1	1.6\|2171897\|35\|NZ_CP017762\|CRISPRCasFinder	2171897-2171931	35	NZ_CP018198	Bacillus safensis strain KCTC 12796BP plasmid pBPL056, complete sequence	29017-29051	9	0.743
NZ_CP017762_2	2.2\|2181146\|29\|NZ_CP017762\|PILER-CR	2181146-2181174	29	CP013001	Bacillus thuringiensis strain XL6 plasmid, complete sequence	34658-34686	9	0.69
NZ_CP017762_2	2.3\|2181078\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181078-2181109	32	NZ_CP043858	Arcobacter cibarius strain H743 plasmid pACIB, complete sequence	62161-62192	9	0.719
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	MF974398	Leptospira mayottensis 200901116 plasmid p2_L200901116, complete sequence	24739-24770	9	0.719
NZ_CP017762_2	2.4\|2181143\|32\|NZ_CP017762\|CRISPRCasFinder,CRT	2181143-2181174	32	NZ_CP030149	Leptospira mayottensis strain MDI272 plasmid p_Lmay_MDI272_tenre, complete sequence	18595-18626	9	0.719
NZ_CP017762_3	3.8\|3353976\|34\|NZ_CP017762\|CRT,PILER-CR,CRISPRCasFinder	3353976-3354009	34	MG945440	UNVERIFIED: Microviridae sp. isolate 5556-1711, complete genome	1582-1615	9	0.735
NZ_CP017762_6	6.3\|3429897\|33\|NZ_CP017762\|PILER-CR	3429897-3429929	33	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	183888-183920	9	0.727
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	MK250016	Prevotella phage Lak-A1, complete genome	275054-275087	9	0.735
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	MK250019	Prevotella phage Lak-A2, complete genome	196188-196221	9	0.735
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	NZ_CP042628	Escherichia coli strain NCYU-25-82 plasmid pNCYU-25-82-1_MCR3, complete sequence	72379-72412	9	0.735
NZ_CP017762_6	6.11\|3429894\|33\|NZ_CP017762\|CRISPRCasFinder	3429894-3429926	33	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	183888-183920	9	0.727
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	KU878088	Bacillus phage AR9, complete genome	12434-12467	10	0.706
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	ACSJ01000017	Clostridium phage D-1873 CLG.Contig173, whole genome shotgun sequence	67114-67147	10	0.706
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	MF360957	Bacillus virus PBS1, complete genome	172994-173027	10	0.706
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	NZ_CP019890	Enterobacter hormaechei strain FRM plasmid unnamed1, complete sequence	117056-117089	11	0.676
NZ_CP017762_6	6.6\|3430098\|34\|NZ_CP017762\|PILER-CR	3430098-3430131	34	NZ_LS999207	Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence	98876-98909	11	0.676
NZ_CP017762_7	7.1\|3438604\|34\|NZ_CP017762\|CRISPRCasFinder	3438604-3438637	34	NC_018878	Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence	497810-497843	11	0.676

1. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NZ_CP012100 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-1, complete sequence) position: , mismatch: 5, identity: 0.828

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
tattaaatcctcctagttttaagttttaa	Protospacer
*.* ***********.****** **** *

2. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NZ_CP045607 (Bacillus cereus strain SB1 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.828

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
tattaaatcctcctaactttaagttttaa	Protospacer
*.* ************.***** **** *

3. spacer 4.5|3361843|33|NZ_CP017762|PILER-CR matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

4. spacer 4.5|3361843|33|NZ_CP017762|PILER-CR matches to MG766219 (Staphylococcus phage vB_SauP_phiAGO1.9, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

5. spacer 4.5|3361843|33|NZ_CP017762|PILER-CR matches to MG766218 (Staphylococcus phage vB_SauP_phiAGO1.3, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

6. spacer 4.6|3361908|33|NZ_CP017762|PILER-CR matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

7. spacer 4.6|3361908|33|NZ_CP017762|PILER-CR matches to MG766219 (Staphylococcus phage vB_SauP_phiAGO1.9, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

8. spacer 4.6|3361908|33|NZ_CP017762|PILER-CR matches to MG766218 (Staphylococcus phage vB_SauP_phiAGO1.3, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

9. spacer 4.11|3361835|33|NZ_CP017762|CRISPRCasFinder,CRT matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

10. spacer 4.11|3361835|33|NZ_CP017762|CRISPRCasFinder,CRT matches to MG766219 (Staphylococcus phage vB_SauP_phiAGO1.9, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

11. spacer 4.11|3361835|33|NZ_CP017762|CRISPRCasFinder,CRT matches to MG766218 (Staphylococcus phage vB_SauP_phiAGO1.3, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

12. spacer 4.12|3361900|33|NZ_CP017762|CRISPRCasFinder,CRT matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

13. spacer 4.12|3361900|33|NZ_CP017762|CRISPRCasFinder,CRT matches to MG766219 (Staphylococcus phage vB_SauP_phiAGO1.9, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

14. spacer 4.12|3361900|33|NZ_CP017762|CRISPRCasFinder,CRT matches to MG766218 (Staphylococcus phage vB_SauP_phiAGO1.3, complete genome) position: , mismatch: 5, identity: 0.848

gatagacaatgttttttacaaatatggtgaggt	CRISPR spacer
gataaaaaatgttttttacaaatatggtaaagg	Protospacer
****.* *********************.*.*

15. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to MF974398 (Leptospira mayottensis 200901116 plasmid p2_L200901116, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
ccttatatcctcctaattttgatctttta	Protospacer
. * * **************.**.*****

16. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
tgttaaaccctcctaattttaatataaaa	Protospacer
*** ***.*************** *   *

17. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NC_008012 (Lawsonia intracellularis PHE/MN1-00 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
ggataacacctcctaattttaaattttta	Protospacer
 *  **  ************** ******

18. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NZ_CP011154 (Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
cattaaatcctcctaactttaagttttga	Protospacer
..* ************.***** **** *

19. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NZ_CP011152 (Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
cattaaatcctcctaactttaagttttga	Protospacer
..* ************.***** **** *

20. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NC_020128 (Lawsonia intracellularis N343 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
ggataacacctcctaattttaaattttta	Protospacer
 *  **  ************** ******

21. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to CP020755 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
cattaaatcctcctaactttaagttttga	Protospacer
..* ************.***** **** *

22. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NC_020385 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
cattaaatcctcctaactttaagttttga	Protospacer
..* ************.***** **** *

23. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NZ_CP021062 (Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
cattaaatcctcctaactttaagttttga	Protospacer
..* ************.***** **** *

24. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NZ_CP030149 (Leptospira mayottensis strain MDI272 plasmid p_Lmay_MDI272_tenre, complete sequence) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
ccttatatcctcctaattttgatctttta	Protospacer
. * * **************.**.*****

25. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to KJ081346 (Bacillus phage BCP8-2, complete genome) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
tttaaactcctcctaattgtaatttaatt	Protospacer
* **** *********** ******  *

26. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NC_027352 (Bacillus phage JBP901, complete genome) position: , mismatch: 6, identity: 0.793

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
tttaaactcctcctaattgtaatttaatt	Protospacer
* **** *********** ******  *

27. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to MN692986 (Marine virus AFVG_117M62, complete genome) position: , mismatch: 6, identity: 0.824

--tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
cttttggttt--tgtttcttttttcttttcttcttt	Protospacer
  * *.****  ***********.** *********

28. spacer 2.1|2181081|29|NZ_CP017762|PILER-CR matches to NZ_CP043858 (Arcobacter cibarius strain H743 plasmid pACIB, complete sequence) position: , mismatch: 7, identity: 0.759

cccctaaaaaataatgattgaaactctac	CRISPR spacer
gatctaaaaaatattgatagaaactctga	Protospacer
  .********** **** ********.

29. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NC_011775 (Bacillus cereus G9842 plasmid pG9842_209, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
gaattaatcctcctaattttaatttttct	Protospacer
 .   **********************.

30. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to NC_042140 (Bacillus virus BM15, complete genome) position: , mismatch: 7, identity: 0.759

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
attaaactcctcctaattctaatttaatt	Protospacer
  **** ***********.******  *

31. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to MH638309 (Bacillus phage Hobo, complete genome) position: , mismatch: 7, identity: 0.759

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
attaaactcctcctaattctaatttaatt	Protospacer
  **** ***********.******  *

32. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP045607 (Bacillus cereus strain SB1 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
tattaaatcctcctaactttaagttttaattg	Protospacer
*.* ************.***** **** *  *

33. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to KJ081346 (Bacillus phage BCP8-2, complete genome) position: , mismatch: 7, identity: 0.781

tgtaaaatcctcctaat-----tttaattttttaaag	CRISPR spacer
tttaaactcctcctaattgtaatttaattttt-----	Protospacer
* **** **********     **********

34. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NC_027352 (Bacillus phage JBP901, complete genome) position: , mismatch: 7, identity: 0.781

tgtaaaatcctcctaat-----tttaattttttaaag	CRISPR spacer
tttaaactcctcctaattgtaatttaattttt-----	Protospacer
* **** **********     **********

35. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to NZ_CP014200 (Escherichia coli strain MRE600 plasmid pMRE600-2, complete sequence) position: , mismatch: 7, identity: 0.794

-tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
ctatgg-ataatgtttctatttcttgttcttcttt	Protospacer
 ***.*  *  ******* ****.***********

36. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to NZ_CP013139 (Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence) position: , mismatch: 7, identity: 0.794

tgttgagatagacgataaaaataaaataatacac-	CRISPR spacer
agttgaaatagacgttaaaaat-aaattttgcaca	Protospacer
 *****.******* ******* ****  *.***

37. spacer 1.3|2171898|34|NZ_CP017762|PILER-CR,CRT matches to NC_018492 (Bacillus cereus FRI-35 plasmid p01, complete sequence) position: , mismatch: 8, identity: 0.765

agaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
attcatgaaaaaagtaaattacaccataagccaa	Protospacer
*   ******************* *** **   *

38. spacer 1.3|2171898|34|NZ_CP017762|PILER-CR,CRT matches to NZ_CP027420 (Staphylococcus cohnii strain FDAARGOS_334 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

agaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
agaaatgaaaaaagtaaataataataagcagatg	Protospacer
******************* *.**.*   .***.

39. spacer 1.3|2171898|34|NZ_CP017762|PILER-CR,CRT matches to KM983333 (Clostridium phage phiCTC2A, complete genome) position: , mismatch: 8, identity: 0.765

agaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
agaaatgaaaaaattaaattaaaaggagatgaaa	Protospacer
************* ******* ** .  * ** *

40. spacer 1.3|2171898|34|NZ_CP017762|PILER-CR,CRT matches to KM983330 (Clostridium phage phiCT19406A, complete genome) position: , mismatch: 8, identity: 0.765

agaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
agaaatgaaaaaattaaattaaaaggagatgaaa	Protospacer
************* ******* ** .  * ** *

41. spacer 1.6|2171897|35|NZ_CP017762|CRISPRCasFinder matches to KM983333 (Clostridium phage phiCTC2A, complete genome) position: , mismatch: 8, identity: 0.771

cagaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
cagaaatgaaaaaattaaattaaaaggagatgaaa	Protospacer
************** ******* ** .  * ** *

42. spacer 1.6|2171897|35|NZ_CP017762|CRISPRCasFinder matches to KM983330 (Clostridium phage phiCT19406A, complete genome) position: , mismatch: 8, identity: 0.771

cagaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
cagaaatgaaaaaattaaattaaaaggagatgaaa	Protospacer
************** ******* ** .  * ** *

43. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to HQ332137 (Prochlorococcus phage P-SSP3 genomic sequence) position: , mismatch: 8, identity: 0.724

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
ataaaaatcctcctaattttactttccat	Protospacer
   ****************** ***..

44. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to GU071107 (Cyanophage P-SSP2, complete genome) position: , mismatch: 8, identity: 0.724

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
ataaaaatcctcctaattttactttccat	Protospacer
   ****************** ***..

45. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to MH319731 (Marine virus AG-345-E02 Ga0172268_11 genomic sequence) position: , mismatch: 8, identity: 0.724

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
ttggtaatcctcctcattttaattttagt	Protospacer
*  . ********* ***********

46. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to JX094431 (Bacillus cereus bacteriophage vB_BceM_Bc431v3, complete genome) position: , mismatch: 8, identity: 0.724

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
attaaattcctcctaattctaatttaact	Protospacer
  **** ***********.******  .

47. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to MG602477 (Bacillus phage BCP01, complete genome) position: , mismatch: 8, identity: 0.724

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
attaaactcctcctaattctaatttaact	Protospacer
  **** ***********.******  .

48. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to KX495186 (Bacillus phage PK16, complete genome) position: , mismatch: 8, identity: 0.724

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
attaaactcctcctaattctaatttaact	Protospacer
  **** ***********.******  .

49. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP016845 (Carnobacterium maltaromaticum strain TMW 2.1581 plasmid pL21581-1, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
attattttcctcctaatttttatcttttaaat	Protospacer
  **   ************* **.*******

50. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP012100 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-1, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
tattaaatcctcctagttttaagttttaatta	Protospacer
*.* ***********.****** **** *  .

51. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
tgttaaaccctcctaattttaatataaaaagt	Protospacer
*** ***.*************** *   **.

52. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP011154 (Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
cattaaatcctcctaactttaagttttgattg	Protospacer
..* ************.***** **** *  *

53. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP011152 (Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
cattaaatcctcctaactttaagttttgattg	Protospacer
..* ************.***** **** *  *

54. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to CP020755 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
cattaaatcctcctaactttaagttttgattg	Protospacer
..* ************.***** **** *  *

55. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NC_020385 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
cattaaatcctcctaactttaagttttgattg	Protospacer
..* ************.***** **** *  *

56. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP021062 (Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
cattaaatcctcctaactttaagttttgattg	Protospacer
..* ************.***** **** *  *

57. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to JX094431 (Bacillus cereus bacteriophage vB_BceM_Bc431v3, complete genome) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaatt----ttttaaag	CRISPR spacer
attaaattcctcctaattctaatttaactttt----	Protospacer
  **** ***********.*****    ****

58. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NC_042140 (Bacillus virus BM15, complete genome) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaat----tttttaaag	CRISPR spacer
attaaactcctcctaattctaatttaattttt----	Protospacer
  **** ***********.****    *****

59. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to MG602477 (Bacillus phage BCP01, complete genome) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaatt----ttttaaag	CRISPR spacer
attaaactcctcctaattctaatttaactttt----	Protospacer
  **** ***********.*****    ****

60. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to KX495186 (Bacillus phage PK16, complete genome) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaatt----ttttaaag	CRISPR spacer
attaaactcctcctaattctaatttaactttt----	Protospacer
  **** ***********.*****    ****

61. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to MH638309 (Bacillus phage Hobo, complete genome) position: , mismatch: 8, identity: 0.75

tgtaaaatcctcctaattttaat----tttttaaag	CRISPR spacer
attaaactcctcctaattctaatttaattttt----	Protospacer
  **** ***********.****    *****

62. spacer 6.3|3429897|33|NZ_CP017762|PILER-CR matches to NC_012219 (Clostridium botulinum plasmid pC2C203U28 DNA, complete sequence, serotype: type C, strain: (C)-203U28) position: , mismatch: 8, identity: 0.758

atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
gctttagatttaattgaagttgaatatgaactt	Protospacer
.. *.*.*********** ***** *******

63. spacer 6.3|3429897|33|NZ_CP017762|PILER-CR matches to NZ_CP029459 (Clostridium novyi strain 150557 plasmid pCN1, complete sequence) position: , mismatch: 8, identity: 0.758

atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
gctttagatttaattgaagttgaatatgaactt	Protospacer
.. *.*.*********** ***** *******

64. spacer 6.3|3429897|33|NZ_CP017762|PILER-CR matches to MH051913 (Enterobacteria phage vB_EcoM_IME281, complete genome) position: , mismatch: 8, identity: 0.758

-atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
gacggc-tctttaattgtatttgaagatgacctt	Protospacer
 *.* *   ******** ************ **

65. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to MK250029 (Prevotella phage Lak-C1, complete genome) position: , mismatch: 8, identity: 0.765

tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
gctgaatacctgtttctttttcttgttcttcttg	Protospacer
  *.. * **************.**********

66. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 8, identity: 0.765

tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
ttttttttcctctttctttttccttttcttttcc	Protospacer
* *  ****** ************ *****.*..

67. spacer 6.11|3429894|33|NZ_CP017762|CRISPRCasFinder matches to NC_012219 (Clostridium botulinum plasmid pC2C203U28 DNA, complete sequence, serotype: type C, strain: (C)-203U28) position: , mismatch: 8, identity: 0.758

atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
gctttagatttaattgaagttgaatatgaactt	Protospacer
.. *.*.*********** ***** *******

68. spacer 6.11|3429894|33|NZ_CP017762|CRISPRCasFinder matches to NZ_CP029459 (Clostridium novyi strain 150557 plasmid pCN1, complete sequence) position: , mismatch: 8, identity: 0.758

atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
gctttagatttaattgaagttgaatatgaactt	Protospacer
.. *.*.*********** ***** *******

69. spacer 6.11|3429894|33|NZ_CP017762|CRISPRCasFinder matches to MH051913 (Enterobacteria phage vB_EcoM_IME281, complete genome) position: , mismatch: 8, identity: 0.758

-atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
gacggc-tctttaattgtatttgaagatgacctt	Protospacer
 *.* *   ******** ************ **

70. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to NC_031015 (Bacillus phage Claudi, complete genome) position: , mismatch: 8, identity: 0.765

---tgttgagatagacgataaaaataaaataatacac	CRISPR spacer
agaacttga---agaatataaaaataaaataatacaa	Protospacer
     ****   ***  *******************

71. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to MT777452 (Bacillus phage Baseball_field, complete genome) position: , mismatch: 8, identity: 0.765

---tgttgagatagacgataaaaataaaataatacac	CRISPR spacer
agaacttga---agaatataaaaataaaataatacaa	Protospacer
     ****   ***  *******************

72. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to NC_049964 (Bacillus phage KonjoTrouble, complete genome) position: , mismatch: 8, identity: 0.765

tgttgagat---agacgataaaaataaaataatacac	CRISPR spacer
---agaaattgaagaatataaaaataaaataatacaa	Protospacer
    **.**   ***  *******************

73. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to MN082624 (Bacillus phage VioletteMad, complete genome) position: , mismatch: 8, identity: 0.765

tgttgagat---agacgataaaaataaaataatacac	CRISPR spacer
---agaaattgaagaatataaaaataaaataatacaa	Protospacer
    **.**   ***  *******************

74. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to NC_031121 (Bacillus phage Aurora, complete genome) position: , mismatch: 8, identity: 0.765

---tgttgagatagacgataaaaataaaataatacac	CRISPR spacer
agaacttga---agaatataaaaataaaataatacaa	Protospacer
     ****   ***  *******************

75. spacer 1.3|2171898|34|NZ_CP017762|PILER-CR,CRT matches to NZ_CP022320 (Bacillus altitudinis strain SGAir0031 plasmid pSGAir0031, complete sequence) position: , mismatch: 9, identity: 0.735

agaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
agaattgaaaaaagtaaattaaaacgccatttca	Protospacer
**** **************** ***...*   .*

76. spacer 1.3|2171898|34|NZ_CP017762|PILER-CR,CRT matches to NZ_CP018198 (Bacillus safensis strain KCTC 12796BP plasmid pBPL056, complete sequence) position: , mismatch: 9, identity: 0.735

agaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
agaattgaaaaaagtaaattaaaacgccatttca	Protospacer
**** **************** ***...*   .*

77. spacer 1.6|2171897|35|NZ_CP017762|CRISPRCasFinder matches to NZ_CP022320 (Bacillus altitudinis strain SGAir0031 plasmid pSGAir0031, complete sequence) position: , mismatch: 9, identity: 0.743

cagaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
cagaattgaaaaaagtaaattaaaacgccatttca	Protospacer
***** **************** ***...*   .*

78. spacer 1.6|2171897|35|NZ_CP017762|CRISPRCasFinder matches to NC_018492 (Bacillus cereus FRI-35 plasmid p01, complete sequence) position: , mismatch: 9, identity: 0.743

cagaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
aattcatgaaaaaagtaaattacaccataagccaa	Protospacer
 *   ******************* *** **   *

79. spacer 1.6|2171897|35|NZ_CP017762|CRISPRCasFinder matches to NZ_CP018198 (Bacillus safensis strain KCTC 12796BP plasmid pBPL056, complete sequence) position: , mismatch: 9, identity: 0.743

cagaaatgaaaaaagtaaattacaacattaggata	CRISPR spacer
cagaattgaaaaaagtaaattaaaacgccatttca	Protospacer
***** **************** ***...*   .*

80. spacer 2.2|2181146|29|NZ_CP017762|PILER-CR matches to CP013001 (Bacillus thuringiensis strain XL6 plasmid, complete sequence) position: , mismatch: 9, identity: 0.69

tgtaaaatcctcctaattttaatttttta	CRISPR spacer
gaattgatcctcctaattttaattattct	Protospacer
 .   .****************** **.

81. spacer 2.3|2181078|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP043858 (Arcobacter cibarius strain H743 plasmid pACIB, complete sequence) position: , mismatch: 9, identity: 0.719

cccctaaaaaataatgattgaaactctacatc	CRISPR spacer
gatctaaaaaatattgatagaaactctgaaaa	Protospacer
  .********** **** ********. *

82. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to MF974398 (Leptospira mayottensis 200901116 plasmid p2_L200901116, complete sequence) position: , mismatch: 9, identity: 0.719

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
ccttatatcctcctaattttgatcttttagtc	Protospacer
. * * **************.**.*****.

83. spacer 2.4|2181143|32|NZ_CP017762|CRISPRCasFinder,CRT matches to NZ_CP030149 (Leptospira mayottensis strain MDI272 plasmid p_Lmay_MDI272_tenre, complete sequence) position: , mismatch: 9, identity: 0.719

tgtaaaatcctcctaattttaattttttaaag	CRISPR spacer
ccttatatcctcctaattttgatcttttagtc	Protospacer
. * * **************.**.*****.

84. spacer 3.8|3353976|34|NZ_CP017762|CRT,PILER-CR,CRISPRCasFinder matches to MG945440 (UNVERIFIED: Microviridae sp. isolate 5556-1711, complete genome) position: , mismatch: 9, identity: 0.735

aaaaggggaaagtcaattggaaagaattaactat	CRISPR spacer
aaaaggggaaagtcaataggtaagtccaaaaaac	Protospacer
***************** ** ***  . **  *.

85. spacer 6.3|3429897|33|NZ_CP017762|PILER-CR matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 9, identity: 0.727

atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
ggacattatttaaatgaatttgaagatgaaata	Protospacer
. ..   ****** **************** **

86. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to MK250016 (Prevotella phage Lak-A1, complete genome) position: , mismatch: 9, identity: 0.735

tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
gctgaatacctgtttctttttcttgctcttcttg	Protospacer
  *.. * **************.**.*******

87. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to MK250019 (Prevotella phage Lak-A2, complete genome) position: , mismatch: 9, identity: 0.735

tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
gctgaatacctgtttctttttcttgctcttcttg	Protospacer
  *.. * **************.**.*******

88. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to NZ_CP042628 (Escherichia coli strain NCYU-25-82 plasmid pNCYU-25-82-1_MCR3, complete sequence) position: , mismatch: 9, identity: 0.735

tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
ttttgaggtctatttctttttcgtgttcttctta	Protospacer
* * *   .**.********** **********

89. spacer 6.11|3429894|33|NZ_CP017762|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 9, identity: 0.727

atgtcaaatttaattgaatttgaagatgaacta	CRISPR spacer
ggacattatttaaatgaatttgaagatgaaata	Protospacer
. ..   ****** **************** **

90. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to KU878088 (Bacillus phage AR9, complete genome) position: , mismatch: 10, identity: 0.706

tgttgagatagacgataaaaataaaataatacac	CRISPR spacer
atgtaatataaatgataaaaataaaataataatg	Protospacer
   *.* ***.*.******************

91. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to ACSJ01000017 (Clostridium phage D-1873 CLG.Contig173, whole genome shotgun sequence) position: , mismatch: 10, identity: 0.706

tgttgagatagacgataaaaataaaataatacac	CRISPR spacer
aatttctatagactatataaataaaataataata	Protospacer
 .**   ****** *** *************

92. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to MF360957 (Bacillus virus PBS1, complete genome) position: , mismatch: 10, identity: 0.706

tgttgagatagacgataaaaataaaataatacac	CRISPR spacer
atgtaatataaatgataaaaataaaataataatg	Protospacer
   *.* ***.*.******************

93. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to NZ_CP019890 (Enterobacter hormaechei strain FRM plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.676

tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
ccggaaggcgtgtttttttttccttttcttcttt	Protospacer
.  ..   * *****.******** *********

94. spacer 6.6|3430098|34|NZ_CP017762|PILER-CR matches to NZ_LS999207 (Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence) position: , mismatch: 11, identity: 0.676

tatagtttcctgtttctttttcctgttcttcttt	CRISPR spacer
ccggaaggcgtgtttttttttccttttcttcttt	Protospacer
.  ..   * *****.******** *********

95. spacer 7.1|3438604|34|NZ_CP017762|CRISPRCasFinder matches to NC_018878 (Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence) position: , mismatch: 11, identity: 0.676

tgttgagatagacgataaaaataaaataatacac	CRISPR spacer
caatccgacagacgataaaaataaaatgattttt	Protospacer
.. *  **.******************.** . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1446872 : 1457788

Streptococcus_phage(88.89%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072741210.1\|1446872_1447952_+	DNA (cytosine-5-)-methyltransferase	A0A2K9V3X0	Faecalibacterium_phage	1.2e-28	58.7
WP_083547208.1\|1448021_1448216_+	hypothetical protein	NA	NA	NA	NA
WP_018705633.1\|1448317_1448632_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	3.1e-43	83.5
WP_072741211.1\|1448645_1449026_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	2.0e-44	73.2
WP_072741212.1\|1449025_1450366_+	DUF87 domain-containing protein	A0A1S5SFB5	Streptococcus_phage	8.1e-173	70.0
WP_072741213.1\|1450593_1451796_+	helix-turn-helix domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.6e-146	62.9
WP_010097509.1\|1451821_1452043_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	1.4e-29	91.8
WP_018705629.1\|1452210_1452711_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	2.4e-61	70.7
WP_072741214.1\|1452770_1453163_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	4.2e-45	66.9
WP_072742385.1\|1455604_1457788_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	2.2e-159	56.1

DBSCAN-SWA_2

1474245 : 1481815

Streptococcus_phage(50.0%)

integrase

attL 1459949:1459964|attR 1483218:1483233

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1459949:1459964	attL	NA	NA	NA	NA
WP_072741225.1\|1474245_1474602_-	helix-turn-helix transcriptional regulator	A0A2K5B2A6	Erysipelothrix_phage	1.2e-43	78.8
WP_072741226.1\|1475202_1475625_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	5.7e-56	78.6
WP_072741227.1\|1475621_1475852_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.1e-28	80.3
WP_072741228.1\|1476426_1476627_+	DUF3173 domain-containing protein	NA	NA	NA	NA
WP_072741229.1\|1476653_1477904_+\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	1.3e-42	34.5
WP_050351777.1\|1477940_1479218_-\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	1.9e-14	24.5
WP_050353461.1\|1479204_1479420_-	DUF3173 domain-containing protein	NA	NA	NA	NA
WP_050351778.1\|1479531_1479723_-	hypothetical protein	NA	NA	NA	NA
WP_050351779.1\|1479755_1480175_-	hypothetical protein	NA	NA	NA	NA
WP_050351780.1\|1480227_1480719_-	hypothetical protein	NA	NA	NA	NA
WP_050351781.1\|1480750_1481815_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1S5SEZ8	Streptococcus_phage	1.8e-21	36.5
1483218:1483233	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1489923 : 1499892

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072741230.1\|1489923_1490970_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.2e-57	38.3
WP_050353464.1\|1490993_1492367_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	6.5e-117	56.0
WP_050351791.1\|1492524_1492917_-	YdcP family protein	NA	NA	NA	NA
WP_050351792.1\|1492965_1493466_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	4.0e-56	63.6
WP_050351793.1\|1493486_1494053_-	hypothetical protein	NA	NA	NA	NA
WP_050351795.1\|1494624_1494867_-	hypothetical protein	NA	NA	NA	NA
WP_050351796.1\|1494938_1495169_-	helix-turn-helix transcriptional regulator	A0A290G4F8	Caldibacillus_phage	1.2e-10	47.8
WP_050351797.1\|1495348_1495693_+	helix-turn-helix transcriptional regulator	A0A1L2BY72	Clostridium_phage	7.8e-11	38.3
WP_050351798.1\|1495761_1496247_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	3.1e-21	40.1
WP_050351799.1\|1496502_1496970_-	hypothetical protein	NA	NA	NA	NA
WP_050351800.1\|1497057_1498074_-	DUF3231 family protein	NA	NA	NA	NA
WP_072741231.1\|1498356_1499892_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	9.1e-19	31.4

DBSCAN-SWA_4

2943494 : 2973075

Staphylococcus_phage(27.27%)

portal,protease,tail,head,terminase,capsid,integrase

attL 2942650:2942666|attR 2963039:2963055

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2942650:2942666	attL	NA	NA	NA	NA
WP_072741685.1\|2943494_2945621_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.8e-233	60.3
WP_072741686.1\|2946119_2947472_+	Ktr system potassium transporter B	NA	NA	NA	NA
WP_072742435.1\|2947871_2949029_-\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	5.4e-40	31.3
WP_156875333.1\|2949147_2949570_-	ImmA/IrrE family metallo-endopeptidase	A0A0S2SXM3	Bacillus_phage	6.8e-33	51.1
WP_072741688.1\|2949581_2950007_-	helix-turn-helix transcriptional regulator	A0A0M4QX29	Bacillus_phage	7.8e-37	60.3
WP_072741689.1\|2950312_2950498_+	helix-turn-helix transcriptional regulator	A0A0M3ULF9	Bacillus_phage	7.3e-16	73.8
WP_072741690.1\|2950498_2950771_+	hypothetical protein	NA	NA	NA	NA
WP_072741691.1\|2950823_2951018_+	hypothetical protein	NA	NA	NA	NA
WP_072741692.1\|2951014_2951233_-	hypothetical protein	Q9T1I9	Lactobacillus_phage	1.4e-13	57.4
WP_072741693.1\|2951290_2952046_+	Bro-N domain-containing protein	A0A2L1IV39	Escherichia_phage	3.0e-15	31.4
WP_072741694.1\|2952046_2952370_+	hypothetical protein	NA	NA	NA	NA
WP_156875334.1\|2952409_2952586_+	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_072741695.1\|2952563_2953046_-	DUF2321 domain-containing protein	U3PDZ3	Staphylococcus_phage	2.5e-39	53.1
WP_072741696.1\|2953221_2953506_+	hypothetical protein	NA	NA	NA	NA
WP_072741697.1\|2953587_2953800_+	hypothetical protein	NA	NA	NA	NA
WP_156875335.1\|2953803_2954046_+	hypothetical protein	NA	NA	NA	NA
WP_072741698.1\|2954082_2954328_+	hypothetical protein	NA	NA	NA	NA
WP_072741699.1\|2954338_2954611_+	hypothetical protein	NA	NA	NA	NA
WP_072741700.1\|2954703_2955354_+	DUF1071 domain-containing protein	A0A126HA30	Lactococcus_phage	2.0e-07	33.6
WP_072741701.1\|2955334_2955919_+	hypothetical protein	NA	NA	NA	NA
WP_072741702.1\|2955915_2956248_+	hypothetical protein	NA	NA	NA	NA
WP_072741703.1\|2956237_2956657_+	hypothetical protein	NA	NA	NA	NA
WP_072741704.1\|2956663_2957284_+	hypothetical protein	NA	NA	NA	NA
WP_072741705.1\|2957453_2958293_+	hypothetical protein	A0A218KCJ2	Bacillus_phage	3.9e-40	33.7
WP_072741706.1\|2958303_2959080_+	DnaC replication protein	A0A1W6JPS4	Staphylococcus_phage	5.8e-38	39.2
WP_072741707.1\|2959076_2959457_+	hypothetical protein	A0A0K2CPB0	Brevibacillus_phage	2.0e-12	39.5
WP_072741708.1\|2959456_2959639_+	hypothetical protein	NA	NA	NA	NA
WP_072741709.1\|2959613_2959880_+	hypothetical protein	NA	NA	NA	NA
WP_072741710.1\|2959876_2960224_+	hypothetical protein	NA	NA	NA	NA
WP_083547263.1\|2960216_2960501_+	hypothetical protein	NA	NA	NA	NA
WP_072741711.1\|2960504_2960888_+	hypothetical protein	NA	NA	NA	NA
WP_072741712.1\|2960901_2961216_+	hypothetical protein	NA	NA	NA	NA
WP_072741713.1\|2961212_2961557_+	hypothetical protein	NA	NA	NA	NA
WP_072741714.1\|2961553_2961805_+	hypothetical protein	NA	NA	NA	NA
WP_156875336.1\|2961801_2961951_+	hypothetical protein	NA	NA	NA	NA
WP_072741715.1\|2962128_2962407_+	hypothetical protein	NA	NA	NA	NA
WP_072741716.1\|2962528_2962714_+	hypothetical protein	NA	NA	NA	NA
WP_072741717.1\|2962710_2963358_+	hypothetical protein	A0A290GJJ6	Caldibacillus_phage	5.2e-40	45.4
2963039:2963055	attR	NA	NA	NA	NA
WP_072741718.1\|2963413_2963686_+	DUF1599 domain-containing protein	A0A2H4J4N1	uncultured_Caudovirales_phage	2.5e-20	60.8
WP_083547360.1\|2963681_2964035_+	Holliday junction resolvase	A0A0A7S133	Clostridium_phage	3.0e-34	56.4
WP_072741720.1\|2964031_2964316_+	hypothetical protein	NA	NA	NA	NA
WP_072741722.1\|2964509_2964695_+	hypothetical protein	NA	NA	NA	NA
WP_156875337.1\|2964707_2965148_+	transcriptional regulator	A0A0K2CZI2	Paenibacillus_phage	7.6e-27	41.8
WP_072741723.1\|2965138_2965330_+	hypothetical protein	NA	NA	NA	NA
WP_072741724.1\|2965495_2965870_+	hypothetical protein	NA	NA	NA	NA
WP_072741725.1\|2965943_2966384_+	hypothetical protein	NA	NA	NA	NA
WP_072741726.1\|2966465_2966831_+	HNH endonuclease	A0A1Q1PW15	Staphylococcus_phage	1.7e-24	47.5
WP_072741727.1\|2966955_2967453_+\|terminase	phage terminase small subunit P27 family	A0A1Q1PVW3	Staphylococcus_phage	8.6e-19	35.5
WP_072741728.1\|2967459_2969187_+	hypothetical protein	A0A2H4JBN3	uncultured_Caudovirales_phage	1.2e-123	42.9
WP_072741729.1\|2969197_2969551_+	hypothetical protein	NA	NA	NA	NA
WP_072741730.1\|2969559_2969757_+	hypothetical protein	NA	NA	NA	NA
WP_072741731.1\|2969763_2971008_+\|portal	phage portal protein	R9QSV8	Staphylococcus_phage	3.9e-68	37.0
WP_072741732.1\|2970970_2971561_+\|head,protease	HK97 family phage prohead protease	Q8SBP9	Clostridium_phage	1.6e-35	46.5
WP_072741733.1\|2971573_2972725_+\|capsid	phage major capsid protein	A0A1J0MFW8	Staphylococcus_phage	1.3e-115	71.2
WP_072741734.1\|2972763_2973075_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA

DBSCAN-SWA_5

2981904 : 2990866

Bacillus_phage(33.33%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072741742.1\|2981904_2984283_+	hypothetical protein	A0A142F1N2	Bacillus_phage	1.6e-115	56.2
WP_072741743.1\|2984296_2984626_+	hypothetical protein	NA	NA	NA	NA
WP_072741744.1\|2984618_2984804_+	hypothetical protein	NA	NA	NA	NA
WP_083547273.1\|2984837_2985122_+	hypothetical protein	NA	NA	NA	NA
WP_072741745.1\|2985283_2985511_-	hypothetical protein	NA	NA	NA	NA
WP_072741746.1\|2985592_2985820_+\|holin	phage holin	A0A0H3UYV6	Geobacillus_virus	1.9e-10	40.0
WP_072741747.1\|2985821_2986985_+	hypothetical protein	A0A2P1JU23	Anoxybacillus_phage	6.4e-57	45.9
WP_072741748.1\|2987296_2987746_-	helix-turn-helix domain-containing protein	A0A142F1N8	Bacillus_phage	3.1e-28	46.2
WP_072741749.1\|2987758_2987974_-	hypothetical protein	NA	NA	NA	NA
WP_082240909.1\|2988053_2988791_-	AP2 domain-containing protein	A8ATW6	Listeria_phage	1.7e-15	35.3
WP_072741750.1\|2988858_2989074_+	hypothetical protein	A0A2I7SCF7	Paenibacillus_phage	1.4e-05	46.3
WP_072741751.1\|2989073_2989388_+	YolD-like family protein	O64030	Bacillus_phage	6.2e-07	37.6
WP_072741752.1\|2989541_2990210_+	DUF4065 domain-containing protein	A0A0A7RUP2	Clostridium_phage	1.6e-31	37.2
WP_072741753.1\|2990662_2990866_-	hypothetical protein	A0A0C5AEJ6	Paenibacillus_phage	1.8e-20	74.6

DBSCAN-SWA_6

3998621 : 4010992

Bacillus_phage(44.44%)

integrase

attL 3996896:3996910|attR 4013899:4013913

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3996896:3996910	attL	NA	NA	NA	NA
WP_072742100.1\|3998621_3999611_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.3e-87	52.6
WP_050352348.1\|4000664_4001120_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_050352349.1\|4001365_4002247_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	2.4e-08	31.4
WP_072742101.1\|4002249_4003209_+	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	2.3e-52	35.4
WP_050352351.1\|4003495_4004440_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.2e-48	38.1
WP_050352352.1\|4004832_4005087_+	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_050352353.1\|4005129_4005717_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.0e-54	53.8
WP_083547324.1\|4006168_4007209_+\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	1.5e-28	26.5
WP_072742102.1\|4007370_4008084_+	hypothetical protein	A0A024AZI4	Bacillus_phage	5.4e-06	22.6
WP_072742103.1\|4008486_4009074_-\|integrase	site-specific integrase	A0A0S2GLG4	Bacillus_phage	2.7e-35	42.1
WP_083547326.1\|4010635_4010992_-	helix-turn-helix transcriptional regulator	A0A0A0RVA6	Bacillus_phage	7.8e-06	40.0
4013899:4013913	attR	NA	NA	NA	NA

DBSCAN-SWA_7

4581439 : 4628944

uncultured_Caudovirales_phage(21.05%)

tRNA,coat,transposase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072742266.1\|4581439_4583017_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_050352814.1\|4583019_4583448_+	hypothetical protein	NA	NA	NA	NA
WP_050352815.1\|4583779_4584343_+\|coat	outer spore coat protein CotE	NA	NA	NA	NA
WP_072742267.1\|4584824_4587419_+	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	5.6e-37	24.9
WP_050352817.1\|4587531_4589433_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	5.2e-64	30.0
WP_072742268.1\|4589493_4589940_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	1.2e-24	40.3
WP_072742269.1\|4589964_4590897_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_050352820.1\|4590940_4591165_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_050352821.1\|4591539_4592463_+	AAA family ATPase	G3MAX6	Bacillus_virus	1.6e-47	39.5
WP_050352822.1\|4592769_4594005_+	GTPase HflX	NA	NA	NA	NA
WP_072742270.1\|4594009_4595236_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_156875388.1\|4595829_4596096_-	hypothetical protein	NA	NA	NA	NA
WP_128743566.1\|4596235_4596877_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.3e-23	34.4
WP_156875389.1\|4596997_4599289_-	DUF1430 domain-containing protein	NA	NA	NA	NA
WP_072742272.1\|4599327_4599687_-	hypothetical protein	NA	NA	NA	NA
WP_050353536.1\|4599965_4600337_+	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	7.3e-07	38.0
WP_050352828.1\|4600671_4602009_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_156875390.1\|4602336_4602534_-	hypothetical protein	NA	NA	NA	NA
WP_050352830.1\|4604007_4604430_-	DUF805 domain-containing protein	NA	NA	NA	NA
WP_072742274.1\|4605610_4606189_-	hypothetical protein	NA	NA	NA	NA
WP_072742275.1\|4606954_4607194_+	hypothetical protein	NA	NA	NA	NA
WP_050352833.1\|4608150_4608378_+\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
WP_050353537.1\|4608382_4608634_+\|coat	spore coat protein CotJB	NA	NA	NA	NA
WP_072742276.1\|4608674_4609070_+\|coat	spore coat protein CotJC	NA	NA	NA	NA
WP_072742277.1\|4609066_4610497_-	recombinase family protein	E5DV73	Deep-sea_thermophilic_phage	3.3e-47	28.1
WP_072742278.1\|4610567_4611221_-	LexA family transcriptional regulator	A0A2H4J386	uncultured_Caudovirales_phage	9.5e-42	45.7
WP_072742279.1\|4611402_4611660_+	helix-turn-helix transcriptional regulator	A0A2H4J2S7	uncultured_Caudovirales_phage	1.7e-15	61.8
WP_072742280.1\|4611941_4612163_+	hypothetical protein	NA	NA	NA	NA
WP_072742281.1\|4612163_4612427_+	hypothetical protein	NA	NA	NA	NA
WP_072742282.1\|4612527_4612731_+	hypothetical protein	NA	NA	NA	NA
WP_072742283.1\|4612933_4613350_+	hypothetical protein	NA	NA	NA	NA
WP_072742284.1\|4613346_4613643_+	VRR-NUC domain-containing protein	A0A2H4J095	uncultured_Caudovirales_phage	2.8e-09	42.9
WP_072742486.1\|4613632_4614832_+	DEAD/DEAH box helicase	A0A2L1IWF6	Streptomyces_phage	2.3e-17	23.5
WP_072742285.1\|4614828_4615728_+	endonuclease	D2IYT8	Enterococcus_phage	3.8e-09	23.6
WP_072742487.1\|4615761_4616136_+	hypothetical protein	A0A2P0ZLA7	Lactobacillus_phage	9.6e-23	50.0
WP_072742286.1\|4616253_4616445_+	hypothetical protein	NA	NA	NA	NA
WP_072742287.1\|4616466_4617384_+	AAA family ATPase	A0A141DZQ7	Streptococcus_phage	1.7e-49	46.0
WP_156875391.1\|4617387_4617528_+	hypothetical protein	NA	NA	NA	NA
WP_072742288.1\|4617527_4617971_+	hypothetical protein	NA	NA	NA	NA
WP_072742289.1\|4617988_4619713_+	DNA polymerase B	A0A1B1P7M5	Bacillus_phage	1.1e-65	30.2
WP_156875392.1\|4619736_4619907_+	hypothetical protein	NA	NA	NA	NA
WP_072742290.1\|4619943_4620246_+	hypothetical protein	L7TJ47	Halovirus	6.4e-17	48.5
WP_072742291.1\|4620285_4622145_+	DNA primase	A0A2H4J1M0	uncultured_Caudovirales_phage	2.4e-58	27.5
WP_072742292.1\|4622666_4623074_+	hypothetical protein	A0A288WG73	Bacillus_phage	1.1e-35	59.5
WP_072742293.1\|4623222_4624731_+\|tail	tail fiber domain-containing protein	B6V2M5	Bacillus_phage	2.3e-67	50.6
WP_072742294.1\|4624835_4625516_+	hypothetical protein	NA	NA	NA	NA
WP_072742295.1\|4625618_4625909_+	hypothetical protein	NA	NA	NA	NA
WP_072742296.1\|4625987_4627229_+	hypothetical protein	NA	NA	NA	NA
WP_072742297.1\|4627340_4627676_+	hypothetical protein	NA	NA	NA	NA
WP_072742298.1\|4627819_4628944_+\|transposase	IS4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

4731865 : 4740057

Bacillus_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050352898.1\|4731865_4732357_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	2.6e-36	46.0
WP_050352899.1\|4732375_4733332_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	7.0e-126	66.9
WP_050352900.1\|4733523_4734567_+	cell wall lytic activity	A0A1J0GW44	Streptomyces_phage	5.3e-10	33.7
WP_050352901.1\|4734691_4735210_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_072742342.1\|4735225_4735834_-	HD domain-containing protein	A0A1D6Y7U0	Golden_Marseillevirus	7.3e-12	28.2
WP_050352903.1\|4735833_4737504_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_050352904.1\|4737820_4738021_+	cold-shock protein	Q9AZD3	Lactococcus_phage	3.4e-19	64.6
WP_072742343.1\|4738320_4740057_+	STAS domain-containing protein	A0A2H4J153	uncultured_Caudovirales_phage	8.1e-48	27.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP017762

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection