CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	15 crisprs	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	10	37	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018300_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_1

365915-366613

Orphan

Consensus_repeat	Method
TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	CRISPRCasFinder

10 spacers

The CRISPR arrays of NZ_CP018300_1

>merge|NZ_CP018300|1|365915-366613|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATGAACGCACCGGTGTCCACATCGCCCGTGTTCGCCACGCCCGTGTTGTAGTCACCGGTGTTGAGGTAGCCCGTGTTGCCACTGCCCGGGTTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTGAAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTGTTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTGAAGCCGCCCGAGTTCGCGAGACCGAAGTTGCCGGTGCCGGTGTTAAAGATGCCGACGTTGCCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAGTTGAACAGCCCGATGTTGTTGCTGCCCGAGTTGAGGCTGCCGATCCCGATCTGGCCGTTGCCGGTGAGCCCGACGCCGATGTTGTTGTTACCGGTATTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTCGCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGATTTGCCAACCCGATGTTGTAGCTGCCCAGGTTCGCCAAGCCGATATCGAAGATCCCGGTGTTGGCGATGCCGATGTTGTTACCGCCGATGTTGACCCCGCCGAAGTTGAGGTCGCCGAGGTTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

>NZ_CP018300|1|1|365915-366613|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATG	AACGCACCGGTGTCCACATCGCCCGTG
TTCGCCACGCCCGTGTTGTAGTCACCGGTGTTG	AGGTAGCCCGTGTTGCCACTGCCCGGG
TTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTG	AAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTG
TTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTG	AAGCCGCCCGAGTTCGCGAGACCGAAG
TTGCCGGTGCCGGTGTTAAAGATGCCGACGTTG	CCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAG
TTGAACAGCCCGATGTTGTTGCTGCCCGAGTTG	AGGCTGCCGATCCCGATCTGGCCGTTGCCGGTG
AGCCCGACGCCGATGTTGTTGTTACCGGTATTC	GCGAAGCCGATGTTGTAGCTGCCGGTG
TTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTC	GCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGA
TTTGCCAACCCGATGTTGTAGCTGCCCAGGTTC	GCCAAGCCGATATCGAAGATCCCGGTG
TTGGCGATGCCGATGTTGTTACCGCCGATGTTG	ACCCCGCCGAAGTTGAGGTCGCCGAGG
TTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003900119.1\|380036_381899_+\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|223520
NZ_CP018300.1\|WP_003401571.1\|364056_364689_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP018300.1\|WP_003401555.1\|362703_362931_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|279710
NZ_CP018300.1\|WP_010886074.1\|360785_362561_+\|PE-family-protein	unknown	unknown	gnl\|CDD\|376422
NZ_CP018300.1\|WP_003401544.1\|359209_360607_-\|sulfatase	unknown	unknown	gnl\|CDD\|293751
NZ_CP018300.1\|WP_003401613.1\|381970_382357_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223403
NZ_CP018300.1\|WP_003898398.1\|378652_379882_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003401597.1\|377411_378068_+\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|226309
NZ_CP018300.1\|WP_003900117.1\|364685_365594_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187670
NZ_CP018300.1\|WP_003401621.1\|383082_383967_+\|family-16-glycosylhydrolase	unknown	unknown	gnl\|CDD\|225182
NZ_CP018300.1\|WP_003401594.1\|376593_377310_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_CP018300.1\|WP_003401538.1\|357622_358408_+\|trans-aconitate-2-methyltransferase	unknown	unknown	gnl\|CDD\|184509
NZ_CP018300.1\|WP_003401540.1\|358396_359200_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226848
NZ_CP018300.1\|WP_003401601.1\|378137_378629_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|379275
NZ_CP018300.1\|WP_003401566.1\|363495_363921_+\|PIN-domain-nuclease	unknown	unknown	gnl\|CDD\|350322
NZ_CP018300.1\|WP_003401589.1\|376053_376536_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003401560.1\|362927_363230_+\|toxin-antitoxin-system-toxin	unknown	unknown	unknown
NZ_CP018300.1\|WP_003401563.1\|363277_363499_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|222832
NZ_CP018300.1\|WP_003401619.1\|382359_383022_-\|DUF3060-domain-containing-protein	unknown	unknown	gnl\|CDD\|371435
NZ_CP018300.1\|WP_003401584.1\|375394_376066_+\|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl\|CDD\|162875

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003900119.1\|380036_381899_+\|Hsp70-family-protein	gnl\|CDD\|223520	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones].	3.71262e-67
NZ_CP018300.1\|WP_003401571.1\|364056_364689_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.46938e-15
NZ_CP018300.1\|WP_003401555.1\|362703_362931_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000113886
NZ_CP018300.1\|WP_010886074.1\|360785_362561_+\|PE-family-protein	gnl\|CDD\|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.70979e-29
NZ_CP018300.1\|WP_003401544.1\|359209_360607_-\|sulfatase	gnl\|CDD\|293751	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase). N-sulfoglucosamine sulfohydrolase (SGSH) belongs to the sulfatase family and catalyses the cleavage of N-linked sulfate groups from the GAGs heparin sulfate and heparin. The active site is characterized by the amino-acid sequence motif C(X)PSR that is highly conserved among most sulfatases. The cysteine residue is post-translationally converted to a formylglycine (FGly) residue, which is crucial for the catalytic process. Loss of function of SGSH results a disease called mucopolysaccharidosis type IIIA (Sanfilippo A syndrome), a fatal childhood-onset neurodegenerative disease with mild facial, visceral and skeletal abnormalities.	5.75322e-137
NZ_CP018300.1\|WP_003401613.1\|381970_382357_+\|hypothetical-protein	gnl\|CDD\|223403	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones].	0.00700797
NZ_CP018300.1\|WP_003401597.1\|377411_378068_+\|L,D-transpeptidase	gnl\|CDD\|226309	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown].	4.28441e-100
NZ_CP018300.1\|WP_003900117.1\|364685_365594_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187670	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs. Classical SDR-like subgroup containing LPOR and related proteins. Protochlorophyllide (Pchlide) reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.69352e-146
NZ_CP018300.1\|WP_003401621.1\|383082_383967_+\|family-16-glycosylhydrolase	gnl\|CDD\|225182	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism].	9.91964e-52
NZ_CP018300.1\|WP_003401594.1\|376593_377310_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	2.34145e-31
NZ_CP018300.1\|WP_003401538.1\|357622_358408_+\|trans-aconitate-2-methyltransferase	gnl\|CDD\|184509	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional.	8.03642e-167
NZ_CP018300.1\|WP_003401540.1\|358396_359200_-\|hypothetical-protein	gnl\|CDD\|226848	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown].	2.12891e-123
NZ_CP018300.1\|WP_003401601.1\|378137_378629_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.69655e-31
NZ_CP018300.1\|WP_003401566.1\|363495_363921_+\|PIN-domain-nuclease	gnl\|CDD\|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.62509e-57
NZ_CP018300.1\|WP_003401563.1\|363277_363499_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|222832	PHA01748, PHA01748, hypothetical protein.	0.00852727
NZ_CP018300.1\|WP_003401619.1\|382359_383022_-\|DUF3060-domain-containing-protein	gnl\|CDD\|371435	pfam11259, DUF3060, Protein of unknown function (DUF3060). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed.	1.8339e-21
NZ_CP018300.1\|WP_003401584.1\|375394_376066_+\|5,6-dimethylbenzimidazole-synthase	gnl\|CDD\|162875	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase. A previously published hypothesis that BluB, involved in cobalamin biosynthesis, is EC 1.16.8.1 (cob(II)yrinic acid a,c-diamide reductase) is now contradicted by newer work ascribing a role in 5,6-dimethylbenzimidazole (DMB) biosynthesis. The BluB protein is related to the nitroreductase family (pfam0881). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	6.73571e-73

>NZ_CP018300.1|WP_003900117.1|364685_365594_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQVT
>NZ_CP018300.1|WP_003401571.1|364056_364689_+|TetR/AcrR-family-transcriptional-regulator
MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET
>NZ_CP018300.1|WP_003401566.1|363495_363921_+|PIN-domain-nuclease
MTDQRWLIDKSALVRLTDSPDMEIWSNRIERGLVHITGVTRLEVGFSAECGEIARREFREPPLSAMPVEYLTPRIEDRALEVQTLLADRGHHRGPSIPDLLIAATAELSGLTVLHVDKDFDAIAALTGQKTERLTHRPPSA
>NZ_CP018300.1|WP_003401563.1|363277_363499_+|ribbon-helix-helix-protein,-CopG-family
MSDVLIRDIPDDVLASLDAIAARLGLSRTEYIRRRLAQDAQTARVTVTAADLRRLRGAVAGLGDPELMRQAWR
>NZ_CP018300.1|WP_003401560.1|362927_363230_+|toxin-antitoxin-system-toxin
MIAPGDIAPRRDSEHELYVAVLSNALHRAADTGRVITCPFIPGRVPEDLLAMVVAVEQPNGTLLPELVQWLHVAALGAPLGNAGVAALREAASVVTALLC
>NZ_CP018300.1|WP_003401555.1|362703_362931_+|ribbon-helix-helix-protein,-CopG-family
MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRVALRDYTAKTVPALDIDAYAQRVYQANRAAGS
>NZ_CP018300.1|WP_010886074.1|360785_362561_+|PE-family-protein
MSFVIAQPEMIAAAAGELASIRSAINAANAAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAAAFHAQVVRTLTVDAGAYASAEAANAGPNMLAAVNAPAQALLGRPLIGNGANGAPGTGQAGGDGGLLFGNGGNGGSGAPGQAGGAGGAAGFFGNGGNGGDGGAGANGGAGGTAGWFFGFGGNGGAGGIGVAGINGGLGGAGGDGGNAGFFGNGGNGGMGGAGAAGVNAVNPGLATPVTPAANGGNGLNLVGVPGTAGGGADGANGSAIGQAGGAGGDGGNASTSGGIGIAQTGGAGGAGGAGGDGAPGGNGGNGGSVEHTGATGSSASGGNGATGGNGGVGAPGGAGGNGGHVSGGSVNTAGAGGKGGNGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGGAGVSATDIAGTGGRGGNGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIGGHGGDGGSVNTPIGGSEAGDGGKGGLGGDGGGRGIFGQFGAGGAGGAGGVGGAGGAGGTGGGGGNGGAIFNAGTPGAAGTGGDGGVGGTGAAGGKGGAGGSGGVNGATGADGAKGLDGATGGKGNNGNPG
>NZ_CP018300.1|WP_003401544.1|359209_360607_-|sulfatase
MTSERATGQRENLLIVHWHDLGRYLGVYHHPDVYSPRLDRLAAEGILFTRAHATAPLCTPSRGSLFTGRYPQSNGLVGLAHHGWEYRTGVQTLPQLLSESGWYSALFGMQHETSYPKRLGFDEFDVSNSYCEYVVAKAQDWLHNRVPALDGQRFLLTAGFFETHRPYPHERYRPADSAAVELPDYLPDTPEVRQDVAEFYGSIATADEAVGRLLDTLADTGLDASTWVVFVTDHGPAFPRAKSTLYDAGTGIALIIRPPTRRAMAPRVYDELFSGVDLVPTLLDLLRLEVPADVEGVSHAPALLAPDTENAAVRDHVYTAKTYHDSFDPIRAIRTKEYSYIENYAPRPLLDLPWDIQESPAGMAVAPLVKAPRPQRELYDLRADPTETNNLLAGDDSTQGVAAIAADLAVRLHDWRQRTADVIPSDFAGSRIAERYTETYLRIHRKTPTGRSAIAADRGIDEHCS
>NZ_CP018300.1|WP_003401540.1|358396_359200_-|hypothetical-protein
MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
>NZ_CP018300.1|WP_003401538.1|357622_358408_+|trans-aconitate-2-methyltransferase
MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLTRYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWVPEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGAVVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQQFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG
>NZ_CP018300.1|WP_003401584.1|375394_376066_+|5,6-dimethylbenzimidazole-synthase
MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPSVGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALGAREEEFLALKVEGILDCAELLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLAARSEGLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWSYPSALATDHHHGE
>NZ_CP018300.1|WP_003401589.1|376053_376536_-|hypothetical-protein
MAVIVRKWFGLGRLPADLRCQVEAEGLIYLAEYVAVTRRFTGVIPGLRASHSIASYVGALAFTEQRVLGTLSMVPKLAGRVVDARWDGPQAGAATAEISPTGLQLDLDVADVDPKFSGQLALHFKATIGEDVLSRLPRRSLAFDVPAEYVNLAVGVTYSP
>NZ_CP018300.1|WP_003401594.1|376593_377310_+|phosphatase-PAP2-family-protein
MTRPQALLAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHDIGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLLLACLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLTVLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYLYFLVCLCVFRPPSIFGAQRASHALSPPVEVSRQPEPEVDTAR
>NZ_CP018300.1|WP_003401597.1|377411_378068_+|L,D-transpeptidase
MSRLLALLCAAVCTGCVAVVLAPVSLAVVNPWFANSVGNATQVVSVVGTGGSTAKMDVYQRTAAGWQPLKTGITTHIGSAGMAPEAKSGYPATPMGVYSLDSAFGTAPNPGGGLPYTQVGPNHWWSGDDNSPTFNSMQVCQKSQCPFSTADSENLQIPQYKHSVVMGVNKAKVPGKGSAFFFHTTDGGPTAGCVAIDDATLVQIIRWLRPGAVIAIAK
>NZ_CP018300.1|WP_003401601.1|378137_378629_-|nuclear-transport-factor-2-family-protein
MCCNGVVTPGDPADIAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSVGTELHFTNRADLVDYLRQALGPGVITEHRVTHPEITVTGDTATGIWYLQDRVIVAEFNFMLIGAAFYHDQYRRTTDGWRISATGYDRTYEATMSLAGLNFNIRPGRALAD
>NZ_CP018300.1|WP_003898398.1|378652_379882_+|hypothetical-protein
MSQSRYAGLSRSELAVLLPELLLIGQLIDRSGMAWCIQAFGRQEMLQIAIEEWAGASPIYTKRMQKALNFEGDDVPTIFKGLQLDIGAPPQFMDFRFTLHDRWHGEFHLDHCGALLDVEPMGDDYVVGMCHTIEDPTFDATAIATNPRAQVRPIHRPPRKPADRHPHCAWTVIIDESYPEAEGIPALDAVRETKAATWELDNVDASDDGLVDYSGPLVSDLDFGAFSHSALVRMADEVCLQMHLLNLSFAIAVRKRAKADAQLAISVNTRQLIGVAGLGAERIHRAMALPGGIEGALGVLELHPLLNPAGYVLAETSPDRLVVHNSPAHADGAWISLCTPASVQPLQAIATAVDPHLKVRISGTDTDWTAELIEADAPASELPEVLVAKVSRGSVFQFEPRRSLPLTVK
>NZ_CP018300.1|WP_003900119.1|380036_381899_+|Hsp70-family-protein
MYDPLGLSIGTTNLVAAGNGGPPVTRRAVLTLYPHCAPKIGVPSQNPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAGADASSSEIAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDAIAALTAVNSELGLPHGSVVGLLDFGGSATYVTLVETKSDSRTSDFQPVSATARYQDFSGSQIDQALLLRVIDQFGYGDDVDPASTAAVGQLGQLREQCRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDLIQDPLTGFIYAFDDMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQPGCAAAMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGDVMVIDHEALTDRELAWSQTDFPSEAPARFEGDSYNEGGPCWSMRLNAVEPPKGPAWRRIRVSQLLIGVSAVVAMTAIGGVALTLTAIERRPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAPLPSAAPAPTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTEPPVTTTSTIPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGAGEPQNPFGSLGSG
>NZ_CP018300.1|WP_003401613.1|381970_382357_+|hypothetical-protein
MGDYGPFGFDPDEFDRVIREGSEGLRDAFERIGRFLSSSGAGTGWSAIFEDLSRRSRPAPETAGEAGDGVWAIYTVDADGGARVEQVYATELDALRANKDNTDPKRKVRFLPYGIAVSVLDDPVDEAQ
>NZ_CP018300.1|WP_003401619.1|382359_383022_-|DUF3060-domain-containing-protein
MIVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSGGYTYPPGPPPPPYSYGGPFGGPSPRSSSGNRAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVPTPTAQPATTLPPAGASLSVSGVNVNRTIACNDSIVSVSGMSNTVVITGHCTSLTVSGMRNSVTVDSVDTIEAAGFNNEVTYHSGSPKISNAGGSNSVQQG
>NZ_CP018300.1|WP_003401621.1|383082_383967_+|family-16-glycosylhydrolase
MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPAAATGGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIEDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF

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Crispr_ID: NZ_CP018300_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_2

668933-669044

Orphan

Consensus_repeat	Method
CCGCCGTTGCCGCCGTTGCCGCCG	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NZ_CP018300_2

>merge|NZ_CP018300|2|668933-669044|CRISPRCasFinder
GCGCCTTGGCTGCCGTTGTTGCCCGTTGGCGACAGCGCTTTGCCGCCGGCCCCGCCGTTGCCGCCGCCGCCGCCGGCGCCGCCGGTCCCGCCAACCCCGCCGGTGCCACCGT

>NZ_CP018300|2|2|668933-669044|CRISPRCasFinder
GCGCCTTGGCTGCCGTTGTTGCCC	GTTGGCGACAGCGCTTTG
CCGCCGGCCCCGCCGTTGCCGCCG	CCGCCGCCGGCGCCGCCGGTC
CCGCCAACCCCGCCGGTGCCACCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003403052.1\|674658_675345_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378485
NZ_CP018300.1\|WP_003402998.1\|657573_659652_+\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	unknown	unknown	gnl\|CDD\|236330
NZ_CP018300.1\|WP_003403008.1\|663530_664673_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_CP018300.1\|WP_003900178.1\|678154_680542_-\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NZ_CP018300.1\|WP_003402995.1\|657281_657548_+\|DUF1918-domain-containing-protein	unknown	unknown	gnl\|CDD\|378101
NZ_CP018300.1\|WP_003403017.1\|673394_673886_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003900174.1\|666126_667431_+\|TIGR03086-family-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|369817
NZ_CP018300.1\|WP_003403065.1\|680679_681402_+\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NZ_CP018300.1\|WP_003403047.1\|674191_674599_+\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350263
NZ_CP018300.1\|WP_003403006.1\|661712_661880_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003403095.1\|681398_682196_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223838
NZ_CP018300.1\|WP_003403101.1\|682197_683085_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223838
NZ_CP018300.1\|WP_003403012.1\|667444_668230_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|225861
NZ_CP018300.1\|WP_003898508.1\|664857_666024_-\|FAD-binding-domain	unknown	unknown	gnl\|CDD\|169028
NZ_CP018300.1\|WP_003898507.1\|661320_661662_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003403055.1\|675498_678132_+\|glycosidase	unknown	unknown	gnl\|CDD\|226067
NZ_CP018300.1\|WP_003403039.1\|673979_674195_+\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|279710
NZ_CP018300.1\|WP_003403007.1\|662129_663521_-\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|237112
NZ_CP018300.1\|WP_003898511.1\|672507_673266_+\|Mut7-C-ubiquitin/RNAse-domain-containing-protein	unknown	unknown	gnl\|CDD\|376668
NZ_CP018300.1\|WP_003403001.1\|659765_661097_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224837

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003403052.1\|674658_675345_-\|hypothetical-protein	gnl\|CDD\|378485	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN. This family is conserved in Mycobacteriaceae and is likely to be a lipoprotein.	5.50369e-72
NZ_CP018300.1\|WP_003402998.1\|657573_659652_+\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	gnl\|CDD\|236330	PRK08665, PRK08665, vitamin B12-dependent ribonucleotide reductase.	0
NZ_CP018300.1\|WP_003403008.1\|663530_664673_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	2.35653e-126
NZ_CP018300.1\|WP_003900178.1\|678154_680542_-\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	2.17737e-22
NZ_CP018300.1\|WP_003402995.1\|657281_657548_+\|DUF1918-domain-containing-protein	gnl\|CDD\|378101	pfam08940, DUF1918, Domain of unknown function (DUF1918). This domain, found in various hypothetical bacterial proteins, has no known function.	7.09713e-28
NZ_CP018300.1\|WP_003900174.1\|666126_667431_+\|TIGR03086-family-protein	gnl\|CDD\|369817	pfam08327, AHSA1, Activator of Hsp90 ATPase homolog 1-like protein. This family includes eukaryotic, prokaryotic and archaeal proteins that bear similarity to a C-terminal region of human activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1/p38). This protein is known to interact with the middle domain of Hsp90, and stimulate its ATPase activity. It is probably a general upregulator of Hsp90 function, particularly contributing to its efficiency in conditions of increased stress. p38 is also known to interact with the cytoplasmic domain of the VSV G protein, and may thus be involved in protein transport. It has also been reported as being underexpressed in Down's syndrome. This region is found repeated in two members of this family.	1.30917e-28
NZ_CP018300.1\|WP_003403065.1\|680679_681402_+\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.76819e-52
NZ_CP018300.1\|WP_003403047.1\|674191_674599_+\|PIN-domain-containing-protein	gnl\|CDD\|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.4948e-60
NZ_CP018300.1\|WP_003403101.1\|682197_683085_+\|ABC-transporter-permease	gnl\|CDD\|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	2.8651e-83
NZ_CP018300.1\|WP_003403095.1\|681398_682196_+\|ABC-transporter-permease	gnl\|CDD\|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	9.02403e-82
NZ_CP018300.1\|WP_003403012.1\|667444_668230_+\|VOC-family-protein	gnl\|CDD\|225861	COG3324, COG3324, Predicted enzyme related to lactoylglutathione lyase [General function prediction only].	9.10504e-38
NZ_CP018300.1\|WP_003898508.1\|664857_666024_-\|FAD-binding-domain	gnl\|CDD\|169028	PRK07588, PRK07588, FAD-binding domain.	0
NZ_CP018300.1\|WP_003403001.1\|659765_661097_-\|hypothetical-protein	gnl\|CDD\|224837	COG1926, COG1926, Predicted phosphoribosyltransferases [General function prediction only].	2.28509e-97
NZ_CP018300.1\|WP_003403055.1\|675498_678132_+\|glycosidase	gnl\|CDD\|226067	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism].	0
NZ_CP018300.1\|WP_003403039.1\|673979_674195_+\|CopG-family-transcriptional-regulator	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000727733
NZ_CP018300.1\|WP_003403007.1\|662129_663521_-\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|237112	PRK12484, PRK12484, nicotinate phosphoribosyltransferase; Provisional.	0
NZ_CP018300.1\|WP_003898511.1\|672507_673266_+\|Mut7-C-ubiquitin/RNAse-domain-containing-protein	gnl\|CDD\|376668	pfam01927, Mut7-C, Mut7-C RNAse domain. RNAse domain of the PIN fold with an inserted Zinc Ribbon at the C-terminus.	8.79716e-68

>NZ_CP018300.1|WP_003403012.1|667444_668230_+|VOC-family-protein
MPKRSEYRQGTPNWVDLQTTDQSAAKKFYTSLFGWGYDDNPVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMPPIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAVGLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSMEIAAGQNYRVLKAGDAEVGGCMEPPMPGVPNHWHVYFAVDDADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ
>NZ_CP018300.1|WP_003900174.1|666126_667431_+|TIGR03086-family-protein
MLEVAAEPTRRRLLQLLAPGERTVTQLASQFTVTRSAISQHLGMLAEAGLVTARKQGRERYYRLDERGVLRLRALMESFWSDELDRLVADAAHYPPSQGDCAMPFEKAVVVPLDPTSTFALITQPDRLRRWMAVAARIELRTGGAYRWTVTPGHSAAGTVIDVDPGKRVVFTWGWEDHGDPPPGGSTVTITLTPVDGGTEVRLVHDGLTAQQAARHAKGWNHFLDRLVVAGQRGDAGPDEWAAAPDPLDELSCAEATLAVLQHVLRGIGASDLTRQTPCTEYDVSQLADHLLRSLAIIGAAAGAQLAPRDVDAPLETQVADAAQAVMEAWRRRGLAGTVELNSNQVPATVPVGILCLEFLVHAWDFAIATGSQVIASEPVSEYVLAVAGKVITPATRNSAGFAAPAAVGSFAPVLDRLIAFTGRQPTAGHVSAT
>NZ_CP018300.1|WP_003898508.1|664857_666024_-|FAD-binding-domain
MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYMIDFWGVGYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMVGDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTAPRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDERSYVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPGVAPKDELRDQFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCISLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAAKFIWFFATRTRFGLWFRNVAMRTMNFGPLATLFAGSVRDDFELPDYTW
>NZ_CP018300.1|WP_003403008.1|663530_664673_-|CapA-family-protein
MAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPVDWRWPWGEALAVLENTATDVCLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHVCALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAARRSALVTVGHERRVIVGSVAAESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGYATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESFRSELRLLYLTVTDPASGNLISLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRVVTRPDNLLEVVPAANLTSKE
>NZ_CP018300.1|WP_003403007.1|662129_663521_-|nicotinate-phosphoribosyltransferase
MAIRQHVGALFTDLYEVTMAQAYWAERMSGTAVFEIFFRKLPPGRSYIMAAGLADVVEFLEAFRFDEQDLRYLRGLGQFSDEFLRWLAGVRFTGDVWAAPEGTVIFPNEPAVQLIAPIIEAQLVETFVLNQIHLQSVLASKAARVVAAARGRPVVDFGARRAHGTDAACKVARTSYLAGAAGTSNLLAARQYGIPTFGTMAHSFVQAFDSEVAAFEAFARLYPATMLLVDTYDTLRGVDHVIELAKRLGNRFDVRAVRLDSGDLDELSKATRARLDTAGLEQVEIFASSGLDENRIAALLAARCPIDGFGVGTQLVVAQDAPALDMAYKLVAYDGSGRTKFSSGKVIYPGRKQVFRKLEHGVFCGDTLGEHGENLPGDPLLVPIMTNGRRIRQHAPTLDGARDWARQQIDALPPELRSLEDTGYSYPVAVSDRIVGELARLRHADTAEAHPGSNVVGAKAKRP
>NZ_CP018300.1|WP_003403006.1|661712_661880_-|hypothetical-protein
MAADPQCTRCKQTIEPGWLYITAHRRGQAGIVDDGAVLIHVPGECPHPGEHVPRS
>NZ_CP018300.1|WP_003898507.1|661320_661662_-|hypothetical-protein
MGEHAIKRHMRQRKPTKHPLAQKRGARILVLTDDPRRSVLIVPGCHLDSMRREKNAYYFQDGNALVGMVVSGGTVEYDADDRTYVVQLTDGRHTTESSFEHSSPSRSPQSDDL
>NZ_CP018300.1|WP_003403001.1|659765_661097_-|hypothetical-protein
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVVCLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPVPVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLATQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGTLEQVAKLACDWFIDHLCGPGPSG
>NZ_CP018300.1|WP_003402998.1|657573_659652_+|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase
MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMPGTVAKAVADALGRGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQRRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMDRSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAKAESPSELPHFNLSVGVTDAFLRAVERNGLHRLVNPRTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTINRANPVPGRGRIEATNPCGEVPLLPYESCNLGSINLARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERGAFPAFTDSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRHLLEVNPCFDRLARDRGFYRDELIAEIAQRGGVRGYPRLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNLPATATVDDVRAIYVAAWKAKVKGITVYRYGSREGQVLSYAAPKPLLAQADTEFSGGCAGRSCEF
>NZ_CP018300.1|WP_003402995.1|657281_657548_+|DUF1918-domain-containing-protein
MKAKVGDWLVIKGATIDQPDHRGLIIEVRSSDGSPPYVVRWLETDHVATVIPGPDAVVVTAEEQNAADERAQHRFGAVQSAILHARGT
>NZ_CP018300.1|WP_003898511.1|672507_673266_+|Mut7-C-ubiquitin/RNAse-domain-containing-protein
MVGYVDVRAYAELNEFVELQARGLTVRRPFRSHQTVKDVLEAMGIPHTEVDLILVNGDPADFSYRPVAGDRIAAYPMFEALDIGSTARLRPAPLRNPRFVVDVNLGQLARLLRLLGFDTRWSSAADDPTLADISLGEQRILLTRDRGLLKRRAITHGLFVHSQHPEEQALEVLRRLDLNGRLAPLSRCLRCNGELAAVSKDEVIGQLEPLTRRYYESFSRCFGCGRIYWPGSHHARLVRLVERLRDQLTTST
>NZ_CP018300.1|WP_003403017.1|673394_673886_-|hypothetical-protein
MTDQSYAVDIAHPPAALLRLVNPILRSLLHTPLAGPLRTQLMVVSFTGRKTGRHFSIPLSAHVIDNDLYALTEAGWKHNFSDGAAAQVVYDGKTTAMRGELIRDRAVVSELFLRAAQAYGVKRGQRMLGLSFRDRRIPTLEEFAEAVDRLKLVAIRLTPADNS
>NZ_CP018300.1|WP_003403039.1|673979_674195_+|CopG-family-transcriptional-regulator
MDKTTVYLPDELKAAVKRAARQRGVSEAQVIRESIRAAVGGAKPPPRGGLYAGSEPIARRVDELLAGFGER
>NZ_CP018300.1|WP_003403047.1|674191_674599_+|PIN-domain-containing-protein
MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
>NZ_CP018300.1|WP_003403052.1|674658_675345_-|hypothetical-protein
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
>NZ_CP018300.1|WP_003403055.1|675498_678132_+|glycosidase
MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE
>NZ_CP018300.1|WP_003900178.1|678154_680542_-|flippase-like-domain-containing-protein
MRVDGRDIGVSGNLLQPLTRRTNDIIRAVLAAIYLVAVITSSLITRPQWVALEKSISEIVGVLSPSQSDLVYLGYGLAILALPFVILIGLIVSRQWKLLGAYAAAGLMAVLPLSISSSRIAAPRWHFDLSDRLATLLAQFLDDPRWIAMLAAVLTVSGPWLPARWRHWWWALLLAFVPIHLVVSAIVPARSLLGLAVGWLVGALVVLVVGTPALEVPLDGAIRALAKRGFAVSGLAVVRPAGPGPLVLSAACEQPNAGACSEALIELYGPHQSGGGALRQLWLKLTLRGTETAPLQASMRRAVEHRALMAIAFGDLGMANTTVIAVSPLDRGWTLYAHRPARGIGISECTKTTPTAHVWEALRTLHDQQISHGDLCSAEITVDNGAVLFGGFGEAEYGATDAQLQSDLAQLLVTTSALYDAEAAVTAAIDTFGKQAILAASRRLTKSAVPKRIRESITDPNAVIASTRAEVMRQTGADQIKAETITRFSRGQLIQLVLIGALVYVAYPFISTVPTFFSQLRTANWWWALLGLAVSALTYVGAAAALWACADGLVGFWKLSIMQVANTFAATTTPAGVGGLALSTRFLQKGGLTAVRATAAVALQQSVQVIVHLVLLILFSALAGTSTDLSHFVPNATVLYLIAGVALGIVGTFLFVPKLRRWLATAVRPKLREVTNDLIALAREPKRLALIVLGCAGTTLGAALALWASIEAFGGGTTFVTVTVVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAALGVPSVLLYRLLTCWLPVFAGWQVMHWLTRHEMI
>NZ_CP018300.1|WP_003403065.1|680679_681402_+|FadR-family-transcriptional-regulator
MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
>NZ_CP018300.1|WP_003403095.1|681398_682196_+|ABC-transporter-permease
MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGLPEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIALFATNVVLTTIGVRFGTGH
>NZ_CP018300.1|WP_003403101.1|682197_683085_+|ABC-transporter-permease
MVESSTASAAAVLRARYPRTAASLDRYGGGTARRLERTGTFARFTRISVVQIGWALRRYRRETLRLVAEIGMGTGAMAVVGGTVAIIGFVTLSGGSLIAIQGFASLGNIGVEAFTGFFAALANTRVAAPIVSGVALAATVGAGATAQLGAMRISEEIDALEVMGIKSISFLVSTRILGGLVVIMPLYALALDMAFTSGQVVTTVFYGQSNGTYEHYFRTFLRPEDVGWSVVEVVIIAVVVMITHCYYGYTASGGPVGVGQAVGRSMRFSLVSVVVVVLLAELALYGVDPNFNLTV

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Crispr_ID: NZ_CP018300_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_3

669113-670090

Orphan

Consensus_repeat	Method
CCGCCGTTGCCGCCGTTGCCGCCG	CRISPRCasFinder

19 spacers

csa3

The CRISPR arrays of NZ_CP018300_3

>merge|NZ_CP018300|3|669113-670090|CRISPRCasFinder
AGGCCCGTCCCGCCCGTGCCGCCGGCCCCGCCCCGGCCGCCGTCAGCGCCGTCGCCGGCGACGCTCCCACCTTGCCCGCCTACGCCGCCGTCGCCGCCGCGGCCGCCGCTGCCGGTAATGGCTCCGGGATTGCCGTCACTACCGGTGCCGCCGTCTCCGCCATTGCCGCCCGCTCCGCCGTTGCCAATCTGCCCGGCGTTTCCGCCGGCGCCACCGGTTCCGCCGTCACCGCCCATGCCCCTGCTGGCATTGCCGCCGTTGCCGCCGTGGCCGCCGGCCCCACCGCTGCCGCGCAGGCTGCCGTTGCCGCCGTTGCCGCCGTTGCCGCCGGCCGCGCCGTTGCCGCTGAGGGCATGGTCGCCGTTGCCGCCGTTGCCGCCGTTGCCGCCGTTGACGTGAATGCTGCTGCTTGAGCCGGTCGCACCGAAAGTGGAGCCGGCGCCGCCACTCCCGCCGGCCCCGCTGGGGCCGGCGTTGCCGCCGTTGCCGCCGTTGCCGCCGATGCCGTTGTTGGTGAACACGCTGCCGTTAGCGCCGTTGCCGCCGTCACCGGGGTCCCCGCCGTTGCCGCCGCTGCCGCCGTTGCCGCCGGCGCCTTGGCTGCCGGTTGTGCCCGCCGGCCCGGCCCCGCCCGGCCCGCCGGTCCCGCCTCGGCCGCCCTTTCCGCCGGCCCCGCCGGCGCCGCCATCCTGGCCGCGGGCACCCGCGGTGGCGCCGTCGGCGCCGTCAATGCCGCGGCCGCCGTTACCGCCAACTCCGCCGGTCCCACCGTCGCCGCCGGCACCGCCGGGGCCTTGGCTGCCGGCGACGCCGTTGGGTGCGGCCCCGCCGTCCCCGCCGTCCCCACCTTTTCCGCCGGTACCGCCAACTCCGCCGGTGCCGCCGGGGTGCCCGTCCGCGCCCGCGCTGGAACCGTTGACACCGTCGCTGCCGGACCCTCCAGTCCCGCCGACGCCGCCGGTGCCGCCGGCCCCGCCG

>NZ_CP018300|3|3|669113-670090|CRISPRCasFinder
AGGCCCGTCCCGCCCGTGCCGCCG	GCCCCGCCCCGGCCGCCGTCAGCGCCGTCGCCGGCGACGCTC
CCACCTTGCCCGCCTACGCCGCCG	TCGCCGCCGCGGCCGCCGCTGCCGGTAATGGCTCCGGGA
TTGCCGTCACTACCGGTGCCGCCG	TCTCCGCCATTGCCGCCCGCT
CCGCCGTTGCCAATCTGCCCGGCG	TTTCCGCCGGCGCCACCGGTT
CCGCCGTCACCGCCCATGCCCCTG	CTGGCATTGCCGCCGTTG
CCGCCGTGGCCGCCGGCCCCACCG	CTGCCGCGCAGGCTGCCGTTG
CCGCCGTTGCCGCCGTTGCCGCCG	GCCGCGCCGTTGCCGCTG
AGGGCATGGTCGCCGTTGCCGCCG	TTGCCGCCGTTGCCGCCGTTGACGTGAATGCTGCTGCTTGAGCCGGTCGCACCGAAAGTG
GAGCCGGCGCCGCCACTCCCGCCG	GCCCCGCTGGGGCCGGCGTTG
CCGCCGTTGCCGCCGTTGCCGCCG	ATGCCGTTGTTGGTGAACACG
CTGCCGTTAGCGCCGTTGCCGCCG	TCACCGGGGTCCCCGCCGTTG
CCGCCGCTGCCGCCGTTGCCGCCG	GCGCCTTGGCTGCCGGTTGTGCCCGCCGGCCCGGCC
CCGCCCGGCCCGCCGGTCCCGCCT	CGGCCGCCCTTTCCGCCGGCC
CCGCCGGCGCCGCCATCCTGGCCG	CGGGCACCCGCGGTG
GCGCCGTCGGCGCCGTCAATGCCG	CGGCCGCCGTTACCGCCAACT
CCGCCGGTCCCACCGTCGCCGCCG	GCACCGCCGGGGCCTTGGCTGCCGGCGACGCCGTTGGGTGCGGCC
CCGCCGTCCCCGCCGTCCCCACCT	TTTCCGCCGGTACCGCCAACT
CCGCCGGTGCCGCCGGGGTGCCCG	TCCGCGCCCGCGCTG
GAACCGTTGACACCGTCGCTGCCG	GACCCTCCAGTCCCGCCGACG
CCGCCGGTGCCGCCGGCCCCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003403052.1\|674658_675345_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378485
NZ_CP018300.1\|WP_003402998.1\|657573_659652_+\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	unknown	unknown	gnl\|CDD\|236330
NZ_CP018300.1\|WP_003403008.1\|663530_664673_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_CP018300.1\|WP_003900178.1\|678154_680542_-\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NZ_CP018300.1\|WP_003402995.1\|657281_657548_+\|DUF1918-domain-containing-protein	unknown	unknown	gnl\|CDD\|378101
NZ_CP018300.1\|WP_003403017.1\|673394_673886_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003900174.1\|666126_667431_+\|TIGR03086-family-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|369817
NZ_CP018300.1\|WP_003403065.1\|680679_681402_+\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NZ_CP018300.1\|WP_003403047.1\|674191_674599_+\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350263
NZ_CP018300.1\|WP_003403006.1\|661712_661880_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003403095.1\|681398_682196_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223838
NZ_CP018300.1\|WP_003403101.1\|682197_683085_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223838
NZ_CP018300.1\|WP_003403012.1\|667444_668230_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|225861
NZ_CP018300.1\|WP_003898508.1\|664857_666024_-\|FAD-binding-domain	unknown	unknown	gnl\|CDD\|169028
NZ_CP018300.1\|WP_003898507.1\|661320_661662_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003403055.1\|675498_678132_+\|glycosidase	unknown	unknown	gnl\|CDD\|226067
NZ_CP018300.1\|WP_003403039.1\|673979_674195_+\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|279710
NZ_CP018300.1\|WP_003403007.1\|662129_663521_-\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|237112
NZ_CP018300.1\|WP_003898511.1\|672507_673266_+\|Mut7-C-ubiquitin/RNAse-domain-containing-protein	unknown	unknown	gnl\|CDD\|376668
NZ_CP018300.1\|WP_003403001.1\|659765_661097_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224837

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003403052.1\|674658_675345_-\|hypothetical-protein	gnl\|CDD\|378485	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN. This family is conserved in Mycobacteriaceae and is likely to be a lipoprotein.	5.50369e-72
NZ_CP018300.1\|WP_003402998.1\|657573_659652_+\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	gnl\|CDD\|236330	PRK08665, PRK08665, vitamin B12-dependent ribonucleotide reductase.	0
NZ_CP018300.1\|WP_003403008.1\|663530_664673_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	2.35653e-126
NZ_CP018300.1\|WP_003900178.1\|678154_680542_-\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	2.17737e-22
NZ_CP018300.1\|WP_003402995.1\|657281_657548_+\|DUF1918-domain-containing-protein	gnl\|CDD\|378101	pfam08940, DUF1918, Domain of unknown function (DUF1918). This domain, found in various hypothetical bacterial proteins, has no known function.	7.09713e-28
NZ_CP018300.1\|WP_003900174.1\|666126_667431_+\|TIGR03086-family-protein	gnl\|CDD\|369817	pfam08327, AHSA1, Activator of Hsp90 ATPase homolog 1-like protein. This family includes eukaryotic, prokaryotic and archaeal proteins that bear similarity to a C-terminal region of human activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1/p38). This protein is known to interact with the middle domain of Hsp90, and stimulate its ATPase activity. It is probably a general upregulator of Hsp90 function, particularly contributing to its efficiency in conditions of increased stress. p38 is also known to interact with the cytoplasmic domain of the VSV G protein, and may thus be involved in protein transport. It has also been reported as being underexpressed in Down's syndrome. This region is found repeated in two members of this family.	1.30917e-28
NZ_CP018300.1\|WP_003403065.1\|680679_681402_+\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.76819e-52
NZ_CP018300.1\|WP_003403047.1\|674191_674599_+\|PIN-domain-containing-protein	gnl\|CDD\|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.4948e-60
NZ_CP018300.1\|WP_003403101.1\|682197_683085_+\|ABC-transporter-permease	gnl\|CDD\|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	2.8651e-83
NZ_CP018300.1\|WP_003403095.1\|681398_682196_+\|ABC-transporter-permease	gnl\|CDD\|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	9.02403e-82
NZ_CP018300.1\|WP_003403012.1\|667444_668230_+\|VOC-family-protein	gnl\|CDD\|225861	COG3324, COG3324, Predicted enzyme related to lactoylglutathione lyase [General function prediction only].	9.10504e-38
NZ_CP018300.1\|WP_003898508.1\|664857_666024_-\|FAD-binding-domain	gnl\|CDD\|169028	PRK07588, PRK07588, FAD-binding domain.	0
NZ_CP018300.1\|WP_003403001.1\|659765_661097_-\|hypothetical-protein	gnl\|CDD\|224837	COG1926, COG1926, Predicted phosphoribosyltransferases [General function prediction only].	2.28509e-97
NZ_CP018300.1\|WP_003403055.1\|675498_678132_+\|glycosidase	gnl\|CDD\|226067	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism].	0
NZ_CP018300.1\|WP_003403039.1\|673979_674195_+\|CopG-family-transcriptional-regulator	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000727733
NZ_CP018300.1\|WP_003403007.1\|662129_663521_-\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|237112	PRK12484, PRK12484, nicotinate phosphoribosyltransferase; Provisional.	0
NZ_CP018300.1\|WP_003898511.1\|672507_673266_+\|Mut7-C-ubiquitin/RNAse-domain-containing-protein	gnl\|CDD\|376668	pfam01927, Mut7-C, Mut7-C RNAse domain. RNAse domain of the PIN fold with an inserted Zinc Ribbon at the C-terminus.	8.79716e-68

>NZ_CP018300.1|WP_003403012.1|667444_668230_+|VOC-family-protein
MPKRSEYRQGTPNWVDLQTTDQSAAKKFYTSLFGWGYDDNPVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMPPIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAVGLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSMEIAAGQNYRVLKAGDAEVGGCMEPPMPGVPNHWHVYFAVDDADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ
>NZ_CP018300.1|WP_003900174.1|666126_667431_+|TIGR03086-family-protein
MLEVAAEPTRRRLLQLLAPGERTVTQLASQFTVTRSAISQHLGMLAEAGLVTARKQGRERYYRLDERGVLRLRALMESFWSDELDRLVADAAHYPPSQGDCAMPFEKAVVVPLDPTSTFALITQPDRLRRWMAVAARIELRTGGAYRWTVTPGHSAAGTVIDVDPGKRVVFTWGWEDHGDPPPGGSTVTITLTPVDGGTEVRLVHDGLTAQQAARHAKGWNHFLDRLVVAGQRGDAGPDEWAAAPDPLDELSCAEATLAVLQHVLRGIGASDLTRQTPCTEYDVSQLADHLLRSLAIIGAAAGAQLAPRDVDAPLETQVADAAQAVMEAWRRRGLAGTVELNSNQVPATVPVGILCLEFLVHAWDFAIATGSQVIASEPVSEYVLAVAGKVITPATRNSAGFAAPAAVGSFAPVLDRLIAFTGRQPTAGHVSAT
>NZ_CP018300.1|WP_003898508.1|664857_666024_-|FAD-binding-domain
MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYMIDFWGVGYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMVGDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTAPRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDERSYVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPGVAPKDELRDQFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCISLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAAKFIWFFATRTRFGLWFRNVAMRTMNFGPLATLFAGSVRDDFELPDYTW
>NZ_CP018300.1|WP_003403008.1|663530_664673_-|CapA-family-protein
MAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPVDWRWPWGEALAVLENTATDVCLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHVCALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAARRSALVTVGHERRVIVGSVAAESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGYATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESFRSELRLLYLTVTDPASGNLISLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRVVTRPDNLLEVVPAANLTSKE
>NZ_CP018300.1|WP_003403007.1|662129_663521_-|nicotinate-phosphoribosyltransferase
MAIRQHVGALFTDLYEVTMAQAYWAERMSGTAVFEIFFRKLPPGRSYIMAAGLADVVEFLEAFRFDEQDLRYLRGLGQFSDEFLRWLAGVRFTGDVWAAPEGTVIFPNEPAVQLIAPIIEAQLVETFVLNQIHLQSVLASKAARVVAAARGRPVVDFGARRAHGTDAACKVARTSYLAGAAGTSNLLAARQYGIPTFGTMAHSFVQAFDSEVAAFEAFARLYPATMLLVDTYDTLRGVDHVIELAKRLGNRFDVRAVRLDSGDLDELSKATRARLDTAGLEQVEIFASSGLDENRIAALLAARCPIDGFGVGTQLVVAQDAPALDMAYKLVAYDGSGRTKFSSGKVIYPGRKQVFRKLEHGVFCGDTLGEHGENLPGDPLLVPIMTNGRRIRQHAPTLDGARDWARQQIDALPPELRSLEDTGYSYPVAVSDRIVGELARLRHADTAEAHPGSNVVGAKAKRP
>NZ_CP018300.1|WP_003403006.1|661712_661880_-|hypothetical-protein
MAADPQCTRCKQTIEPGWLYITAHRRGQAGIVDDGAVLIHVPGECPHPGEHVPRS
>NZ_CP018300.1|WP_003898507.1|661320_661662_-|hypothetical-protein
MGEHAIKRHMRQRKPTKHPLAQKRGARILVLTDDPRRSVLIVPGCHLDSMRREKNAYYFQDGNALVGMVVSGGTVEYDADDRTYVVQLTDGRHTTESSFEHSSPSRSPQSDDL
>NZ_CP018300.1|WP_003403001.1|659765_661097_-|hypothetical-protein
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVVCLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPVPVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLATQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGTLEQVAKLACDWFIDHLCGPGPSG
>NZ_CP018300.1|WP_003402998.1|657573_659652_+|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase
MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMPGTVAKAVADALGRGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQRRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMDRSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAKAESPSELPHFNLSVGVTDAFLRAVERNGLHRLVNPRTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTINRANPVPGRGRIEATNPCGEVPLLPYESCNLGSINLARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERGAFPAFTDSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRHLLEVNPCFDRLARDRGFYRDELIAEIAQRGGVRGYPRLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNLPATATVDDVRAIYVAAWKAKVKGITVYRYGSREGQVLSYAAPKPLLAQADTEFSGGCAGRSCEF
>NZ_CP018300.1|WP_003402995.1|657281_657548_+|DUF1918-domain-containing-protein
MKAKVGDWLVIKGATIDQPDHRGLIIEVRSSDGSPPYVVRWLETDHVATVIPGPDAVVVTAEEQNAADERAQHRFGAVQSAILHARGT
>NZ_CP018300.1|WP_003898511.1|672507_673266_+|Mut7-C-ubiquitin/RNAse-domain-containing-protein
MVGYVDVRAYAELNEFVELQARGLTVRRPFRSHQTVKDVLEAMGIPHTEVDLILVNGDPADFSYRPVAGDRIAAYPMFEALDIGSTARLRPAPLRNPRFVVDVNLGQLARLLRLLGFDTRWSSAADDPTLADISLGEQRILLTRDRGLLKRRAITHGLFVHSQHPEEQALEVLRRLDLNGRLAPLSRCLRCNGELAAVSKDEVIGQLEPLTRRYYESFSRCFGCGRIYWPGSHHARLVRLVERLRDQLTTST
>NZ_CP018300.1|WP_003403017.1|673394_673886_-|hypothetical-protein
MTDQSYAVDIAHPPAALLRLVNPILRSLLHTPLAGPLRTQLMVVSFTGRKTGRHFSIPLSAHVIDNDLYALTEAGWKHNFSDGAAAQVVYDGKTTAMRGELIRDRAVVSELFLRAAQAYGVKRGQRMLGLSFRDRRIPTLEEFAEAVDRLKLVAIRLTPADNS
>NZ_CP018300.1|WP_003403039.1|673979_674195_+|CopG-family-transcriptional-regulator
MDKTTVYLPDELKAAVKRAARQRGVSEAQVIRESIRAAVGGAKPPPRGGLYAGSEPIARRVDELLAGFGER
>NZ_CP018300.1|WP_003403047.1|674191_674599_+|PIN-domain-containing-protein
MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
>NZ_CP018300.1|WP_003403052.1|674658_675345_-|hypothetical-protein
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
>NZ_CP018300.1|WP_003403055.1|675498_678132_+|glycosidase
MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE
>NZ_CP018300.1|WP_003900178.1|678154_680542_-|flippase-like-domain-containing-protein
MRVDGRDIGVSGNLLQPLTRRTNDIIRAVLAAIYLVAVITSSLITRPQWVALEKSISEIVGVLSPSQSDLVYLGYGLAILALPFVILIGLIVSRQWKLLGAYAAAGLMAVLPLSISSSRIAAPRWHFDLSDRLATLLAQFLDDPRWIAMLAAVLTVSGPWLPARWRHWWWALLLAFVPIHLVVSAIVPARSLLGLAVGWLVGALVVLVVGTPALEVPLDGAIRALAKRGFAVSGLAVVRPAGPGPLVLSAACEQPNAGACSEALIELYGPHQSGGGALRQLWLKLTLRGTETAPLQASMRRAVEHRALMAIAFGDLGMANTTVIAVSPLDRGWTLYAHRPARGIGISECTKTTPTAHVWEALRTLHDQQISHGDLCSAEITVDNGAVLFGGFGEAEYGATDAQLQSDLAQLLVTTSALYDAEAAVTAAIDTFGKQAILAASRRLTKSAVPKRIRESITDPNAVIASTRAEVMRQTGADQIKAETITRFSRGQLIQLVLIGALVYVAYPFISTVPTFFSQLRTANWWWALLGLAVSALTYVGAAAALWACADGLVGFWKLSIMQVANTFAATTTPAGVGGLALSTRFLQKGGLTAVRATAAVALQQSVQVIVHLVLLILFSALAGTSTDLSHFVPNATVLYLIAGVALGIVGTFLFVPKLRRWLATAVRPKLREVTNDLIALAREPKRLALIVLGCAGTTLGAALALWASIEAFGGGTTFVTVTVVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAALGVPSVLLYRLLTCWLPVFAGWQVMHWLTRHEMI
>NZ_CP018300.1|WP_003403065.1|680679_681402_+|FadR-family-transcriptional-regulator
MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
>NZ_CP018300.1|WP_003403095.1|681398_682196_+|ABC-transporter-permease
MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGLPEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIALFATNVVLTTIGVRFGTGH
>NZ_CP018300.1|WP_003403101.1|682197_683085_+|ABC-transporter-permease
MVESSTASAAAVLRARYPRTAASLDRYGGGTARRLERTGTFARFTRISVVQIGWALRRYRRETLRLVAEIGMGTGAMAVVGGTVAIIGFVTLSGGSLIAIQGFASLGNIGVEAFTGFFAALANTRVAAPIVSGVALAATVGAGATAQLGAMRISEEIDALEVMGIKSISFLVSTRILGGLVVIMPLYALALDMAFTSGQVVTTVFYGQSNGTYEHYFRTFLRPEDVGWSVVEVVIIAVVVMITHCYYGYTASGGPVGVGQAVGRSMRFSLVSVVVVVLLAELALYGVDPNFNLTV

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Crispr_ID: NZ_CP018300_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_4

688295-688371

TypeV-U4

Consensus_repeat	Method
TGAGGTGCGGCGTGAGCGCGGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018300_4

>merge|NZ_CP018300|4|688295-688371|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGTAGCGCGAACGGCAAGCCGAACCGTTGGACCCTGAGGTGCGGCGTGAGCGCGGGT

>NZ_CP018300|4|4|688295-688371|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGT	AGCGCGAACGGCAAGCCGAACCGTTGGACCC
TGAGGTGCGGCGTGAGCGCGGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003403052.1\|674658_675345_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378485
NZ_CP018300.1\|WP_003900973.1\|694173_694680_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP018300.1\|WP_003403137.1\|693423_693837_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350248
NZ_CP018300.1\|WP_003403101.1\|682197_683085_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223838
NZ_CP018300.1\|WP_003403148.1\|695307_696069_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP018300.1\|WP_003403122.1\|691108_691501_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350335
NZ_CP018300.1\|WP_003403095.1\|681398_682196_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223838
NZ_CP018300.1\|WP_003403139.1\|693833_694070_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224913
NZ_CP018300.1\|WP_003403065.1\|680679_681402_+\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NZ_CP018300.1\|WP_003403047.1\|674191_674599_+\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350263
NZ_CP018300.1\|WP_003900178.1\|678154_680542_-\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NZ_CP018300.1\|WP_003403144.1\|694793_695264_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236751
NZ_CP018300.1\|WP_003403055.1\|675498_678132_+\|glycosidase	unknown	unknown	gnl\|CDD\|226067
NZ_CP018300.1\|WP_003403125.1\|691497_691755_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|226603
NZ_CP018300.1\|WP_003900181.1\|685328_686774_+\|virulence-factor-Mce-family-protein	unknown	unknown	gnl\|CDD\|273384
NZ_CP018300.1\|WP_003403039.1\|673979_674195_+\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|279710
NZ_CP018300.1\|WP_003403119.1\|689506_691057_+\|MCE-family-protein	unknown	unknown	gnl\|CDD\|224380
NZ_CP018300.1\|WP_070890821.1\|683090_684305_+\|MCE-family-protein	unknown	unknown	gnl\|CDD\|378749
NZ_CP018300.1\|WP_003403128.1\|691937_693173_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292
NZ_CP018300.1\|WP_003403164.1\|696125_696437_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377032

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003403052.1\|674658_675345_-\|hypothetical-protein	gnl\|CDD\|378485	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN. This family is conserved in Mycobacteriaceae and is likely to be a lipoprotein.	5.50369e-72
NZ_CP018300.1\|WP_003900973.1\|694173_694680_-\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.10494e-27
NZ_CP018300.1\|WP_003403137.1\|693423_693837_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350248	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins. This subfamily includes Mycobacterium tuberculosis VapC27 and VapC40. It belongs to the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	9.76945e-42
NZ_CP018300.1\|WP_003403101.1\|682197_683085_+\|ABC-transporter-permease	gnl\|CDD\|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	2.8651e-83
NZ_CP018300.1\|WP_003403148.1\|695307_696069_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.00442e-84
NZ_CP018300.1\|WP_003403122.1\|691108_691501_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350335	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 toxin of the VapBC toxin/antitoxin (TA) system. This family belongs to the PIN_VapC4-5_FitB-like subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. M. tuberculosis VapC4 interacts with, and cleaves tRNA44Cys-GCA. M. tuberculosis VapC5 has endonucleolytic activity with RNA, this activity is low with dsRNA, and no activity has been demonstrated on dsDNA. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.73431e-57
NZ_CP018300.1\|WP_003403095.1\|681398_682196_+\|ABC-transporter-permease	gnl\|CDD\|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	9.02403e-82
NZ_CP018300.1\|WP_003403139.1\|693833_694070_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|224913	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription].	1.50922e-07
NZ_CP018300.1\|WP_003403065.1\|680679_681402_+\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.76819e-52
NZ_CP018300.1\|WP_003403047.1\|674191_674599_+\|PIN-domain-containing-protein	gnl\|CDD\|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.4948e-60
NZ_CP018300.1\|WP_003900178.1\|678154_680542_-\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	2.17737e-22
NZ_CP018300.1\|WP_003403144.1\|694793_695264_-\|HAMP-domain-containing-protein	gnl\|CDD\|236751	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB.	1.39186e-13
NZ_CP018300.1\|WP_003403055.1\|675498_678132_+\|glycosidase	gnl\|CDD\|226067	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism].	0
NZ_CP018300.1\|WP_003403125.1\|691497_691755_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	2.38527e-16
NZ_CP018300.1\|WP_003900181.1\|685328_686774_+\|virulence-factor-Mce-family-protein	gnl\|CDD\|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.51384e-92
NZ_CP018300.1\|WP_003403039.1\|673979_674195_+\|CopG-family-transcriptional-regulator	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000727733
NZ_CP018300.1\|WP_003403119.1\|689506_691057_+\|MCE-family-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	2.75938e-80
NZ_CP018300.1\|WP_070890821.1\|683090_684305_+\|MCE-family-protein	gnl\|CDD\|378749	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative. Mce4_CUP1 is a family of putative Mce4 transporters of cholesterol. The domain is found associated with pfam02470. The full TCDB classification for this family in conjunction with PF02470 is TC:3.A.1.27.4.	2.04898e-114
NZ_CP018300.1\|WP_003403128.1\|691937_693173_-\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.27416e-77
NZ_CP018300.1\|WP_003403164.1\|696125_696437_+\|hypothetical-protein	gnl\|CDD\|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	0.00241752

>NZ_CP018300.1|WP_003900181.1|685328_686774_+|virulence-factor-Mce-family-protein
MRTLTEFNRGRVGMMGAVVTVLVVGVAQSFTSVPMLFATPTYYAQFADTGGINTGDKVEIAGVNVGLVRSLAIRGNRVLIGFSLPGKTIGMQSRAAIRTDTILGRKNLEIEPRGSEPLKPNGFLPLAQTTTPYQIYDAFVDVTKAATGWDIDAVKRSLNVLSETFDQTAPHLSAALEGVKAFSDTVGRRGEQIEQLLANANRIARVLGDRSEQVNGLLVNAKTLLAAFKQRSQALRILLTNVSEASAQVSGLITDNPNLNHVLAQLRTVSEELVKRKNELADVAVLLGRYTAALTEAVGSGPFFKAMVVNLLPYQILQPWVDAAFKKRGIDPENFWRSAGLPEFRWPDPNGTRFPNGAPPAAPPVREGTPKHPGPAVPPGTPCSYTPAAGALPRPDTPLPCAGATVGPFGGPDFPAPLDVQPSPPNPDGPPPTPGILSAGRPGEPAPAVPGIPMPLPPNAPPGARTQPLEPFPDGTGGSNQ
>NZ_CP018300.1|WP_070890821.1|683090_684305_+|MCE-family-protein
MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLGYKQFRGEFTPKTELTMVASRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVTTEFNTLFETITSIAEKVDPIELNATLSAVAQALDGLGGKFGESIVNGNQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELFCMIRNFHDAAPKVADAVGGNGYSLAAAGTILGAPNPYVYPDNLPRVNAHGGPGGRPGCWQTITRELWPAPYLVMDTGASLAPYNHVELGQPMFTEYVWGRQYGENTINP
>NZ_CP018300.1|WP_003403101.1|682197_683085_+|ABC-transporter-permease
MVESSTASAAAVLRARYPRTAASLDRYGGGTARRLERTGTFARFTRISVVQIGWALRRYRRETLRLVAEIGMGTGAMAVVGGTVAIIGFVTLSGGSLIAIQGFASLGNIGVEAFTGFFAALANTRVAAPIVSGVALAATVGAGATAQLGAMRISEEIDALEVMGIKSISFLVSTRILGGLVVIMPLYALALDMAFTSGQVVTTVFYGQSNGTYEHYFRTFLRPEDVGWSVVEVVIIAVVVMITHCYYGYTASGGPVGVGQAVGRSMRFSLVSVVVVVLLAELALYGVDPNFNLTV
>NZ_CP018300.1|WP_003403095.1|681398_682196_+|ABC-transporter-permease
MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGLPEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIALFATNVVLTTIGVRFGTGH
>NZ_CP018300.1|WP_003403065.1|680679_681402_+|FadR-family-transcriptional-regulator
MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
>NZ_CP018300.1|WP_003900178.1|678154_680542_-|flippase-like-domain-containing-protein
MRVDGRDIGVSGNLLQPLTRRTNDIIRAVLAAIYLVAVITSSLITRPQWVALEKSISEIVGVLSPSQSDLVYLGYGLAILALPFVILIGLIVSRQWKLLGAYAAAGLMAVLPLSISSSRIAAPRWHFDLSDRLATLLAQFLDDPRWIAMLAAVLTVSGPWLPARWRHWWWALLLAFVPIHLVVSAIVPARSLLGLAVGWLVGALVVLVVGTPALEVPLDGAIRALAKRGFAVSGLAVVRPAGPGPLVLSAACEQPNAGACSEALIELYGPHQSGGGALRQLWLKLTLRGTETAPLQASMRRAVEHRALMAIAFGDLGMANTTVIAVSPLDRGWTLYAHRPARGIGISECTKTTPTAHVWEALRTLHDQQISHGDLCSAEITVDNGAVLFGGFGEAEYGATDAQLQSDLAQLLVTTSALYDAEAAVTAAIDTFGKQAILAASRRLTKSAVPKRIRESITDPNAVIASTRAEVMRQTGADQIKAETITRFSRGQLIQLVLIGALVYVAYPFISTVPTFFSQLRTANWWWALLGLAVSALTYVGAAAALWACADGLVGFWKLSIMQVANTFAATTTPAGVGGLALSTRFLQKGGLTAVRATAAVALQQSVQVIVHLVLLILFSALAGTSTDLSHFVPNATVLYLIAGVALGIVGTFLFVPKLRRWLATAVRPKLREVTNDLIALAREPKRLALIVLGCAGTTLGAALALWASIEAFGGGTTFVTVTVVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAALGVPSVLLYRLLTCWLPVFAGWQVMHWLTRHEMI
>NZ_CP018300.1|WP_003403055.1|675498_678132_+|glycosidase
MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE
>NZ_CP018300.1|WP_003403052.1|674658_675345_-|hypothetical-protein
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
>NZ_CP018300.1|WP_003403047.1|674191_674599_+|PIN-domain-containing-protein
MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
>NZ_CP018300.1|WP_003403039.1|673979_674195_+|CopG-family-transcriptional-regulator
MDKTTVYLPDELKAAVKRAARQRGVSEAQVIRESIRAAVGGAKPPPRGGLYAGSEPIARRVDELLAGFGER
>NZ_CP018300.1|WP_003403119.1|689506_691057_+|MCE-family-protein
MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVGIGRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNGYQIPTDASANVHSVSAVGEQFVDLVSTRTSGPYLRHGQTITTTTVPSQIGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAHDVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPAVRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQALVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQPPPCLTGFLPASEWRSPADTSTAPLPKGTYCRIPMDASNVVRGARNNPCVDVPGKRAATPRECRSNEAYVPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGINPLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAGADGWKVMLAPTG
>NZ_CP018300.1|WP_003403122.1|691108_691501_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MNVRRALADTSVFIGIEATRFDPDRFAGYEWGVSVVTLGELRLGVLQASGPEAAARRLSTYQLAQRFEPLGIDEAVSEAWALLVSKLRAAKLRVPINDSWIAATAVAHGIAILTQDNDYAAMPDVEVITI
>NZ_CP018300.1|WP_003403125.1|691497_691755_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MSATIPARDLRNHTAEVLRRVAAGEEIEVLKDNRPVARIVPLKRRRQWLPAAEVIGELVRLGPDTTNLGEELRETLTQTTDDVRW
>NZ_CP018300.1|WP_003403128.1|691937_693173_-|ATP-binding-protein
MGVVERAIAPSVLAALADTPVVVVNGARQVGKTTLVARLDYPGSSEVVSLDDVANRDAARDDPRAFVSRPVDTLVIDEAQLEPGLFRAIKAEVDRDRRPGRFLLTGSARLLSAPDMADALVGRVEIIELWPFSQGERAGIADGFVDALFTAPRELIHGSDMRRADLVDRIATGGFPDIVARSPSRRRAWFDNYLTTATQSVIREISPIERLAEMPRVLRLCAARTGAELNVSALANDLSIPARTTAGYLALLEAAFLIHRVPAWSTNLSRKVIRRPKLVVSDSGLACHLLGVTGATLDRPGRPLGPLLETFVANEIRKQLTWSTERPSLWHFRDRGGAEVDLVLEHPDGRVCGIEVKATSTPRAEDLRGLRYLAERLDDRFQFGVLLTAAPEATPFGPTLAALPVSTLWAG
>NZ_CP018300.1|WP_003403137.1|693423_693837_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MKPPLAVDTSVAIPLLVRTHTAHAAVVAWWAHREAALCGHALAETYSVLTRLPRDLRLAPMDAARLLTERFAAPLLLSSRTTEHLPRVLAQFEITGGAVYDALVALAAAEHRAELATRDARAKDTYEKIGVHVVVAA
>NZ_CP018300.1|WP_003403139.1|693833_694070_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKAVVDAAGRIVVPKPLREALGLQPGSTVEISRYGAGLHLIPTGRTARLEEENGVLVATGETTIDDEVVFGLIDSGRK
>NZ_CP018300.1|WP_003900973.1|694173_694680_-|sensor-histidine-kinase
MPITPLLHESVARFAATGADITTRAEPDLFVSIDPDHLRRILTAVLDNAITHGDGEIAVTAHARDGAVDIGVRDHGPGFADHFLPVAFDRFTRADTARGGRGSGLGLAIVAALTTTHGGHANATNHPDGGAELRITLPTPRPPFHEELPRITSSDTKDPNREHDTSDQ
>NZ_CP018300.1|WP_003403144.1|694793_695264_-|HAMP-domain-containing-protein
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
>NZ_CP018300.1|WP_003403148.1|695307_696069_-|response-regulator-transcription-factor
MADETTMRAGRGPGRACGRVSGVRILVVEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR
>NZ_CP018300.1|WP_003403164.1|696125_696437_+|hypothetical-protein
MNRIVQFGVSAVAAAAIGIGAGSGIAAAFDGEDEVTGPDADRARAAAVQAVPGGTAGEVETETGEGAAAYGVLVTRPDGTRVEVHLDRDFRVLDTEPADGDGG

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Crispr_ID: NZ_CP018300_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_5

922012-922959

Orphan

Consensus_repeat	Method
CGGGGCCGGCGGNNCCGGCGG	CRT

19 spacers

csa3

The CRISPR arrays of NZ_CP018300_5

>merge|NZ_CP018300|5|922012-922959|CRT
CGGCGGCGGAGGGACCGGCGGGTCCGGCGTCAGCGGCGGGGCGGGCGGAGATGGCGGGGCCGGCGGGATCTTGTTCGGCGCCGGCGGGGCCGGCGGCGCGGGCGGGGCCGTCACGGGAACCGGCGCCACCGGCGGGTCCGGTGGGGCCGGCGGTGGAGCCTTGCTGTTTGGGGCCGGTGGGGCCGGTGGAGCCGGCGGGTCCAGCGGGATTGGCGGGTTCGCCGCGGGCGGGGCCGGTGGGCCCGGAGGGGCCGGTGGGCTGTTCAACGGCGGCGGGGCCGGCGGGGCCGGCGGGTCCGGCGTCAGCGGCGGGGCTGGCGGGGAGGGCGGGGCCGGCGGGGCCGGTGGCCTGTTCGCCGGTGGCGGGGCCGGCGGGGCCGGCGGATCGGGCAACAACGTCGGGGGGGCCGGCGGGGCCGGTGGGGTCGGTGGGCTGTTCGGGGCCGGCGGGGCCGGCGGATCCGGCGGCGGCGGTAGCGTTGCTGGCGACGGTGGGGCCGGCGGCAACGCGGGCTTGCTCGCCCCCGGTCTCGCCGGCGGTGCCGGCGGTGGCGGCGGGCAGGGTTTTGACACCGGCGGGGCCGGCGGGCCCGGCGGCGACGCCGGCCTGCTGGTCGGCTCCGGCGGGGTCGGAGGTGCCGGCGGATTCGGCCTCACTACGGGTGGGCCTGGGGCGGCCGGCGGCGACGCCGGCCTGCTGTTCGGCTCCGGCGGCGCTGGCGGGGCCGGCGGCTCCGGCCGAACCGACCTCGGCGGCGCTGGCGGGGCCGGCGGCAAGGCCGGGCTGATCGGCAACGGCGGTAACGGCGGGGCCGGCGGGGCCGGCGGGAACGGCGGCGGGGACGGCGGGCCCGGTGGAGCCGCCTTCGGGCTCGGTAACGGCGGCAACGGCGGCAACGGGGGGACCGGCACGTCCGCGGGCAGCCCCGGTGCCGGCGGCGCCGGTGG

>NZ_CP018300|5|1|922012-922959|CRT
CGGCGGCGGAGGGACCGG	CGGGTCCGGCGTCAGCGGCGGGGCGGGCGGAGATGGCGGGGCCGGCGGGATCTTGTT
CGGCGCCGGCGGGGCCGG	CGGCGCGGGCGGGGCCGTCACGGGAACCGGCGCCACCGG
CGGGTCCGGTGGGGCCGG	CGGTGGAGCCTTGCTGTT
TGGGGCCGGTGGGGCCGG	TGGAGCCGGCGGGTCCAGCGGGATTGGCGGGTTCGCCGCGGG
CGGGGCCGGTGGGCCCGG	AGGGGCCGGTGGGCTGTTCAACGGCGG
CGGGGCCGGCGGGGCCGG	CGGGTCCGGCGTCAGCGGCGGGGCTGGCGGGGAGGG
CGGGGCCGGCGGGGCCGG	TGGCCTGTTCGCCGGTGG
CGGGGCCGGCGGGGCCGG	CGGATCGGGCAACAACGTCGG
GGGGGCCGGCGGGGCCGG	TGGGGTCGGTGGGCTGTT
CGGGGCCGGCGGGGCCGG	CGGATCCGGCGGCGGCGGTAGCGTTGC
TGGCGACGGTGGGGCCGG	CGGCAACGCGGGCTTGCTCGCCCCCGGTCTCGCCGGCGG
TGCCGGCGGTGGCGGCGG	GCAGGGTTTTGACACCGGCGG
GGCCGGCGGGCCCGGCGG	CGACGCCGGCCTGCTGGTCGGCTCCGGCGG
GGTCGGAGGTGCCGGCGG	ATTCGGCCTCACTACGGGTGGGCCTGGGGC
GGCCGGCGGCGACGCCGG	CCTGCTGTTCGGCTCCGGCGGCGCTGGCGG
GGCCGGCGGCTCCGGCCG	AACCGACCTCGGCGGCGCTGGCGG
GGCCGGCGGCAAGGCCGG	GCTGATCGGCAACGGCGGTAACGGCGGGGCCGGCGG
GGCCGGCGGGAACGGCGG	CGGGGACGGCGGGCCCGGTGGAGCCGCCTTCGGGCTCGG
TAACGGCGGCAACGGCGG	CAACGGGGGGACCGGCACGTCCGCGGGCAGCCCCGG
TGCCGGCGGCGCCGGTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003898609.1\|930646_931417_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|279735
NZ_CP018300.1\|WP_003404335.1\|916132_916525_-\|Ni(II)/Co(II)-sensing-metalloregulatory-transcriptional-repressor-KmtR	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|197713
NZ_CP018300.1\|WP_003898601.1\|911868_913038_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NZ_CP018300.1\|WP_003404382.1\|934038_935331_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP018300.1\|WP_003404384.1\|935314_936319_+\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NZ_CP018300.1\|WP_087902221.1\|926815_928077_-\|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP018300.1\|WP_003898602.1\|915025_916081_+\|DUF2236-domain-containing-protein	unknown	unknown	gnl\|CDD\|226188
NZ_CP018300.1\|WP_003404376.1\|932383_933244_-\|proline-specific-peptidase-family-protein	unknown	unknown	gnl\|CDD\|188121
NZ_CP018300.1\|WP_003900218.1\|916966_917257_+\|transposase	unknown	unknown	gnl\|CDD\|223747
NZ_CP018300.1\|WP_003404336.1\|916582_917005_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NZ_CP018300.1\|WP_003898600.1\|909648_911703_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|273029
NZ_CP018300.1\|WP_003404373.1\|931503_932316_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|316372
NZ_CP018300.1\|WP_003404368.1\|928929_929958_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227198
NZ_CP018300.1\|WP_010886090.1\|923228_925877_-\|PE-family-protein	unknown	unknown	gnl\|CDD\|376422
NZ_CP018300.1\|WP_009938275.1\|914303_914945_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP018300.1\|WP_003906455.1\|928205_928859_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227186
NZ_CP018300.1\|WP_003404321.1\|913125_914142_-\|acyl-ACP-desaturase	unknown	unknown	gnl\|CDD\|153109
NZ_CP018300.1\|WP_003404379.1\|933519_933762_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003404349.1\|917361_918267_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225852
NZ_CP018300.1\|WP_003404352.1\|918285_919101_-\|TIGR04255-family-protein	unknown	unknown	gnl\|CDD\|275082

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003898609.1\|930646_931417_+\|hypothetical-protein	gnl\|CDD\|279735	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase.	1.08627e-95
NZ_CP018300.1\|WP_003404335.1\|916132_916525_-\|Ni(II)/Co(II)-sensing-metalloregulatory-transcriptional-repressor-KmtR	gnl\|CDD\|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	9.15024e-22
NZ_CP018300.1\|WP_003898601.1\|911868_913038_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	7.36004e-168
NZ_CP018300.1\|WP_003404382.1\|934038_935331_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.02174e-28
NZ_CP018300.1\|WP_003404384.1\|935314_936319_+\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	3.51316e-109
NZ_CP018300.1\|WP_087902221.1\|926815_928077_-\|IS3-like-element-IS987-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NZ_CP018300.1\|WP_003898602.1\|915025_916081_+\|DUF2236-domain-containing-protein	gnl\|CDD\|226188	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown].	7.60533e-137
NZ_CP018300.1\|WP_003404376.1\|932383_933244_-\|proline-specific-peptidase-family-protein	gnl\|CDD\|188121	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily. This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase.	8.19399e-156
NZ_CP018300.1\|WP_003900218.1\|916966_917257_+\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.02344e-12
NZ_CP018300.1\|WP_003404336.1\|916582_917005_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	8.91868e-24
NZ_CP018300.1\|WP_003898600.1\|909648_911703_-\|LCP-family-protein	gnl\|CDD\|273029	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain. This model describes a domain of unknown function that is found in the predicted extracellular domain of a number of putative membrane-bound proteins. One of these is proteins psr, described as a penicillin binding protein 5 (PDP-5) synthesis repressor. Another is Bacillus subtilis LytR, described as a transcriptional attenuator of itself and the LytABC operon, where LytC is N-acetylmuramoyl-L-alanine amidase. A third is CpsA, a putative regulatory protein involved in exocellular polysaccharide biosynthesis. Besides the region of strong similarily represented by this model, these proteins share the property of having a short putative N-terminal cytoplasmic domain and transmembrane domain forming a signal-anchor. [Regulatory functions, Other].	3.89123e-67
NZ_CP018300.1\|WP_003404373.1\|931503_932316_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|316372	pfam13847, Methyltransf_31, Methyltransferase domain. This family appears to have methyltransferase activity.	8.13208e-31
NZ_CP018300.1\|WP_003404368.1\|928929_929958_-\|hypothetical-protein	gnl\|CDD\|227198	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown].	5.33791e-171
NZ_CP018300.1\|WP_010886090.1\|923228_925877_-\|PE-family-protein	gnl\|CDD\|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	5.97682e-28
NZ_CP018300.1\|WP_009938275.1\|914303_914945_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.99497e-07
NZ_CP018300.1\|WP_003906455.1\|928205_928859_-\|hypothetical-protein	gnl\|CDD\|227186	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction only].	9.88702e-114
NZ_CP018300.1\|WP_003404321.1\|913125_914142_-\|acyl-ACP-desaturase	gnl\|CDD\|153109	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain. Acyl-Acyl Carrier Protein Desaturase (Acyl_ACP_Desat) is a mu-oxo-bridged diiron-carboxylate enzyme, which belongs to a broad superfamily of ferritin-like proteins and catalyzes the NADPH and O2-dependent formation of a cis-double bond in acyl-ACPs. Acyl-ACP desaturases are found in higher plants and a few bacterial species (Mycobacterium tuberculosis, M. leprae, M. avium and Streptomyces avermitilis, S. coelicolor). In plants, Acyl-ACP desaturase is a plastid-localized, covalently ACP linked, soluble desaturase that introduces the first double bound into saturated fatty acids, resulting in the corresponding monounsaturated fatty acid. Members of this class of soluble desaturases are specific for a particular substrate chain length and introduce the double bond between specific carbon atoms. For example, delta 9 stearoyl-ACP is specific for stearic acid and introduces a double bond between carbon 9 and 10 to yield oleic acid in the ACP-bound form. The enzymatic reaction requires molecular oxygen, NAD(P)H, NAD(P)H ferredoxin oxido-reductase and ferredoxin. The enzyme is active in the homodimeric form; the monomer consists mainly of alpha-helices with the catalytic diiron center buried within a four-helix bundle. Integral membrane fatty acid desaturases that introduce double bonds into fatty acid chains, acyl-CoA desaturases of animals, yeasts, and fungi, and acyl-lipid desaturases of cyanobacteria and higher plants, are distinct from soluble acyl-ACP desaturases, lack diiron centers, and are not included in this CD.	1.08695e-140
NZ_CP018300.1\|WP_003404349.1\|917361_918267_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	4.29544e-95
NZ_CP018300.1\|WP_003404352.1\|918285_919101_-\|TIGR04255-family-protein	gnl\|CDD\|275082	TIGR04255, hypothetical_protein, TIGR04255 family protein. Members of this uncharacterized protein family are found broadly but sporadically among bacteria and archaea, including members of the genera Mycobacterium, Nostoc, Acinetobacter, Planctomyces, Geobacter, Streptomyces, Methanospirillum, etc. The function is unknown.	1.96412e-45

>NZ_CP018300.1|WP_003404352.1|918285_919101_-|TIGR04255-family-protein
MLPETNQDEVQPNAPVALVTVEIRHPTTDSLTESANRELKHLLINDLPIERQAQDVSWGMTAPGGAPTPVADRFVRYVNRDNTTAASLKNQAIVVETTAYRSFEAFTDVVMRVVDARAQVSSIVGLERIGLRFVLEIRVPAGVDGRITWSNWIDEQLLGPQRFTPGGLVLTEWQGAAVYRELQPGKSLIVRYGPGMGQALDPNYHLRRITPAQTGPFFLLDIDSFWTPSGGSIPEYNRDALVSTFQDLYGPAQVVFQEMITSRLKDELLRQ
>NZ_CP018300.1|WP_003404349.1|917361_918267_+|class-I-SAM-dependent-methyltransferase
MVRADRDRWDLATSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAVGMDVYTRLVDWQIPVEGDSEFDPQRMATGMACRTRFFDQFFLDATHSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLGAEPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQDALFDNITALSAPGSRLAFEFVPDTAIFADERWRNYHNRMSELGFDIDLNELVYHGQRGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDDELATAFADLTYSSATLMR
>NZ_CP018300.1|WP_003900218.1|916966_917257_+|transposase
MGPSSKTCHACRHVQDIGWDEKWQCDGCSITHQRDDNAAINLARYEEPPSVVGPVGAAVKRGADRKTGPGPAGGREARKGTGHPAGEQPRDGVLVA
>NZ_CP018300.1|WP_003404336.1|916582_917005_-|nucleoside-deaminase
MPAGMAGFRRWAQTNDPTAHAESLAIRAACTKLGTEHLVGTTLNVLAHPCPMCYGSLYYCSPDEVVFLTSRDAYEPHYVDDRRYFEPATFYDEFAKEWQDRRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG
>NZ_CP018300.1|WP_003404335.1|916132_916525_-|Ni(II)/Co(II)-sensing-metalloregulatory-transcriptional-repressor-KmtR
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQHLAKLRMARLVRTRRDGTTIFYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSVAKASATKDVG
>NZ_CP018300.1|WP_003898602.1|915025_916081_+|DUF2236-domain-containing-protein
MTQDTSATCPLTSTVQDSSPVAGQLGRPIGFRGLAGGCPVSPLGYESPPLPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFFRERWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKGVDGAGRRYHALNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQLFDEHVQWYRMYGMSMRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDLTELPKPPFAQRVPDWLWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLRRDEWLHRRFGDIVRLVFALVPFRFRKHPRARAGWDRATGRIPADAPLVQTPARNLPPPDERDNPTHYCPKV
>NZ_CP018300.1|WP_009938275.1|914303_914945_-|TetR/AcrR-family-transcriptional-regulator
MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRHAGLRERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPREAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEWMPNFIELLQRKLSRIVDPVLQKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPAGPHN
>NZ_CP018300.1|WP_003404321.1|913125_914142_-|acyl-ACP-desaturase
MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYALGGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQWVNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADENLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVIAVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLELACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
>NZ_CP018300.1|WP_003898601.1|911868_913038_-|tRNA-dihydrouridine-synthase-DusB
MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRIGIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAFTGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFPAGSALRRALAMVKTFDELDCLLDRLDGTVPFPDSATGARGRQGSPARVALPDGWLTDPDDCRVPEGADAMGSGG
>NZ_CP018300.1|WP_003898600.1|909648_911703_-|LCP-family-protein
MSDGESAAPWARLSESAFPDGVDRWITVPPATWVAAQGPRDTQNVGCHATGAVSVADLIARLGPAFPDLPTHRHVAPEPEPSGRGPKVHDDADDQQDTEAIAIPAHSLEFLSELPDLRAANYPRADHARREPELPGKQLTGSARVRPLRIRRTSPAPAKPAPNSGRRPMVLAARSLAALFAALALALTGGAWQWSASKNSRLNMVSALDPHSGDIVNPSGQHGDENFLLVGMDSRAGANANIGAGDAEDAGGARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWNPETGKYGPIYDEKTGTMGPRLVYTETKLNSAFSFGGPKCLVKVIQKLSGLSINRFIAIDFVGFARMVEALGGVEVCSTTPLRDYELGTVLEHAGRQVIDGPTALNYVRARQVTTESNGDYGRIKRQQLFLSSLLRSMISTDTLFNLSRLNNVVNMFIGNSYVDNVKTKDLVELGRSLQHMAAGHVTFVTVPTGITDQNGDEPPRTSDMKALFTAIIDDDPLPLENDHNAQRLGNTPSTPPTTTKKAPQAGLTNEIQHQQVTTTSPKEVTVQVSNSTGQAGLATTATDQLKRNGFNVMAPDDYPSSLLATTVFFSPGNEQAAATVAAVFGQSKIERVTGIGQLVQVVLGQDFSAVRAPLPSGSTVSVQISRNSSSPPTKLPEDLTVTNAADTTCE
>NZ_CP018300.1|WP_010886090.1|923228_925877_-|PE-family-protein
MSFVIAAPDLVAMATEDLAGIGASLTAANAAAAVPTSGLLAAAGDEVSAAIAALFSSHGQQYQAMSAQAAAFHARFVQALAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRPFIGNGTNGAPGTGEAGGPGGWLLGNGGNGGSGAPGQTGGAGGAAGLLGHGGTGGAGGTGASGGKGGTGGWLWGSGGAGGAGGSGGGSGGAGGNALMFGIGGNGGAGGAASGVGNGGVGGAGGAGGALVAIGGAGGAGGAATTGTGGAGGAGSNALGLFLGLGGSGGQGGDSAMGSGGAGGAGGSGGAASPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALDLSWGGAGGNGGAATTGTGGAGGTGGFAVAPDFIGFGAAYGGAGGLGGAATGAGGTGGTGGVGAGGFAALGVGVGGAGGAGGAATETGGIGGAGGLGVGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGVGGVGGAATDTGGNGGAGGSGTGLLGGVGGAGGHGGGASVGTGGSGGAGGDGFGFVGAGGNGGNAGTGVGVNGANGGNGGSATGALAAVGGAGAAGGDATSGTGGFGGAGGSARGLIFALGGAGAAGGDASTGVGGPGGPGGTGTASSPFGIAIAIGGAGAQGGAGTSGATGGAGGDGVFEGIAVLGLGFGGAAGAGGAATGDGATGGAGGFGGAGAGIANFLGFSVLHGGAGGAGGTATGTGGNGGAGGGGGLSSPVILGIGIGGAGGDGGGALGVLGGMGGDGGDGGEAVAVGIAVGGAGGAGGAAPTGNGGAGGNGGDALGLVGVGGNGGNAGTGFGANTGGNGGDTTIVVNGMLAPSTLGYGGNGGNGVNGGAGGTGGKAGVFGAPGQNGLP
>NZ_CP018300.1|WP_087902221.1|926815_928077_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NZ_CP018300.1|WP_003906455.1|928205_928859_-|hypothetical-protein
MLVGAQCRDLLHWRFCRGVPPRATNDTDIAGTLNNWDHFEAIRATFRALGSTGHRFLIADRAVDALPFGEVESPTGTTRHPPGNQLMNVHGCTDAYLRADVLPLPGGLTVHLPQPPNYAVLKLHAWLDRSADHDYKDGPDLALVVHWYAGDLDRLYAKPDQWALRRHDFDLRTAAAALLGHDMRASVSAPEAAVLATRATQADHDLLAQHFAVGRPG
>NZ_CP018300.1|WP_003404368.1|928929_929958_-|hypothetical-protein
MDQIGADLAEAVERHLTEYGVRVLGGLSALNSAHPESLDLEIDAHPLTITALYLPHLSATAALQAWDTAGAGSPLLVVGPRLHPSSAETLRARGLWYIDGAGNAYLRHQGGLLIDVRGRRSAVSAQPGTLGDGLHSDGPRNPFTPKRAQVVCVLLDAPQLVDAPLRAIAASAGVSVGMAKETMDTLRTTGFFEHLGSRRRLVRTDELLDLWAAAYPGGLGRANKLLVASGDIHTWSAPDGLAVAVSGEQALPDEIRNPESLMLYVDTPAPGLPADLLIHNRWHRDPHGSIVIRKLFWRNLPDEQPGLAPTALIYADLLASREPRQVEVAHLMRRQDERLARL
>NZ_CP018300.1|WP_003898609.1|930646_931417_+|hypothetical-protein
MRLIGRLRLLMVGLVVICGACACDRVSAGRWSESPSATSWPVRPVNTTTPSGPVPPVSEAARAAGLVDVRGVVPDAAIDLRYATANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPHGQVLVFWDCYRPHDVQVRMFDVVPNPAWVARPGKYAHSHEAGRSVDVTFASAQRQCPSVRRSGELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYSGEWWHFDGPGAGVDRPILEVPVD
>NZ_CP018300.1|WP_003404373.1|931503_932316_+|class-I-SAM-dependent-methyltransferase
MNDKRRAIYTHGYHESVLRSHRRRTAENSAGYLLPYLVPGLSVLDVGCGPGTITVDLAARVVPGSVTGVEPTDDALSLARAEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVADPVRALQEMRRVCTPGGIVAARDADYSGFIWFPKLPALDRWLDLYERAARANGGEPDAGRRLLSWARAAGFDDVTPTASVWCFATASAREWWGLVWADRILQSDLAHQLVDSGLATAAQLEEISTAWREWAAAPDGWLAIPHGEILCRA
>NZ_CP018300.1|WP_003404376.1|932383_933244_-|proline-specific-peptidase-family-protein
MEGTIAVPGGRVWFQRIGGGPGRPLLVVHGGPGLPHNYLAPLRRLSDEREVIFWDQLGCGNSACPSDVDLWTMNRSVAEMATVAEALALTRFHIFSHSWGGMLAQQYVLDKAPDAVSLTIANSTASIPEFSASLVSLKSCLDVATRSAIDRHEAAGTTHSAEYQAAIRTWNETYLCRTRPWPRELTEAFANMGTEIFETMFGPSDFRIVGNVRDWDVVDRLADIAVPTLLVVGRFDECSPEHMREMQGRIAGSRLEFFESSSHMPFIEEPARFDRVMREFLRLHDI
>NZ_CP018300.1|WP_003404379.1|933519_933762_+|hypothetical-protein
MVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAALCLPLARALRRPTPSAMTTD
>NZ_CP018300.1|WP_003404382.1|934038_935331_+|MFS-transporter
MRYTGPERCSGDGQVRAAGDRYSTVIWLLGGNLLVRSAGFGYPFLAYHVAGRGHGAGAVGAVVAAYGLGWAVGQLLCGWLVDRVGARVTLVSTMLVAAAVLVLMAGLHTVPGLLVGAMIAGLVCDAPRPVLGAVIAELVADPQRRAQLDGWRYGWVLNIGAAITGGVGGVVAGWLDTPVLYWINGIGCAIFAGLAGRCIPADVCRRTESGLRACTAMSKVGYRQALSDKRLVLLAVSGLATLTTLMGFFAAVPMLMSASGLGVGAYGWVQLINALAVVAVTPLLTPWLSKQLALGPRPDILAGAGVWVTLCMAAAGLARTTVGFSVAAAACSPGEIAWFVVAAGIVHRIAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFFGAALCLPLARVLAAASCGPLSSKEPSRDSYQ
>NZ_CP018300.1|WP_003404384.1|935314_936319_+|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MTRTSEGLAAFVVDQLEELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAAAALGEGDVIITTHRPHAQHVGTDAPLGPVIADMLGATAGDLEGADEDAHIADPRAGLPAAIRVVKQSPLLAIGHAYALWLRDTGRVTLCVTQDCDVDADAFNEAADLAAVWQLPVVILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVRARAGGGPTLVQAITYRTTDFSGSDRGGYRDLAGSEQFLDPLIFARRRLIAAGTTRGRLDEQERAACQQVADAVAFAKARARPNGGGPISRPTSGWHQQPKTRF

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Crispr_ID: NZ_CP018300_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_6

1187265-1187373

Orphan

Consensus_repeat	Method
GACAGCCAGCCGGCTGACCCGCCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018300_6

>merge|NZ_CP018300|6|1187265-1187373|CRISPRCasFinder
GACAGCCAGCCGGCTGACCCGCCGTTGCCGCCGTTGCCGGCGTTGCCGCCGCCGCCGCCGGTGCCGGCGTCGCCGCCGTTGCCGGACAGCCAGCCGGCCGACCCGCCGT

>NZ_CP018300|6|5|1187265-1187373|CRISPRCasFinder
GACAGCCAGCCGGCTGACCCGCCGT	TGCCGCCGTTGCCGGCGTTGCCGCCGCCGCCGCCGGTGCCGGCGTCGCCGCCGTTGCCG
GACAGCCAGCCGGCCGACCCGCCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003405730.1\|1197665_1199060_+\|cystathionine-beta-synthase	unknown	unknown	gnl\|CDD\|273464
NZ_CP018300.1\|WP_003405719.1\|1192227_1193064_+\|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl\|CDD\|227102
NZ_CP018300.1\|WP_003405708.1\|1188458_1190222_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226849
NZ_CP018300.1\|WP_003906506.1\|1195374_1196319_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238874
NZ_CP018300.1\|WP_003405629.1\|1178339_1179404_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226326
NZ_CP018300.1\|WP_003405642.1\|1181689_1182772_-\|patatin-family-protein	unknown	unknown	gnl\|CDD\|132866
NZ_CP018300.1\|WP_003405712.1\|1190218_1190992_-\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|180295
NZ_CP018300.1\|WP_003405633.1\|1179456_1179930_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NZ_CP018300.1\|WP_003405724.1\|1194104_1195322_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|181146
NZ_CP018300.1\|WP_003405722.1\|1193179_1194031_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380141
NZ_CP018300.1\|WP_014585511.1\|1184369_1186373_-\|PE-family-protein	unknown	unknown	gnl\|CDD\|376422
NZ_CP018300.1\|WP_003405636.1\|1179963_1180827_+\|class-II-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|238889
NZ_CP018300.1\|WP_003900268.1\|1196715_1197609_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223730
NZ_CP018300.1\|WP_003901991.1\|1199261_1199984_+\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP018300.1\|WP_003405649.1\|1183383_1183950_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380416
NZ_CP018300.1\|WP_003405651.1\|1183946_1184342_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238724
NZ_CP018300.1\|WP_003405625.1\|1176632_1178264_+\|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl\|CDD\|341284
NZ_CP018300.1\|WP_003405716.1\|1191003_1192041_-\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|235533
NZ_CP018300.1\|WP_003405640.1\|1180831_1181689_+\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|224666
NZ_CP018300.1\|WP_003405645.1\|1182852_1183272_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375114

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003405730.1\|1197665_1199060_+\|cystathionine-beta-synthase	gnl\|CDD\|273464	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family].	0
NZ_CP018300.1\|WP_003405719.1\|1192227_1193064_+\|Bax-inhibitor-1/YccA-family-protein	gnl\|CDD\|227102	COG4760, COG4760, Predicted membrane protein [Function unknown].	5.73324e-144
NZ_CP018300.1\|WP_003405708.1\|1188458_1190222_-\|hypothetical-protein	gnl\|CDD\|226849	COG4425, COG4425, Predicted membrane protein [Function unknown].	0
NZ_CP018300.1\|WP_003906506.1\|1195374_1196319_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238874	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it turn are loaded onto the acyl carrier protein FeeL. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.12459e-53
NZ_CP018300.1\|WP_003405629.1\|1178339_1179404_+\|hypothetical-protein	gnl\|CDD\|226326	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown].	2.06007e-162
NZ_CP018300.1\|WP_003405642.1\|1181689_1182772_-\|patatin-family-protein	gnl\|CDD\|132866	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6. Bacterial patatin-like phospholipase domain containing protein 6. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. This group includes YCHK and rssA from Escherichia coli as well as Ylbk from Bacillus amyloliquefaciens.	2.32416e-86
NZ_CP018300.1\|WP_003405712.1\|1190218_1190992_-\|enoyl-CoA-hydratase	gnl\|CDD\|180295	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional.	8.35159e-173
NZ_CP018300.1\|WP_003405633.1\|1179456_1179930_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	6.32324e-09
NZ_CP018300.1\|WP_003405724.1\|1194104_1195322_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|181146	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase.	0
NZ_CP018300.1\|WP_003405722.1\|1193179_1194031_+\|hypothetical-protein	gnl\|CDD\|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	0.000138679
NZ_CP018300.1\|WP_014585511.1\|1184369_1186373_-\|PE-family-protein	gnl\|CDD\|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.1141e-30
NZ_CP018300.1\|WP_003405636.1\|1179963_1180827_+\|class-II-glutamine-amidotransferase	gnl\|CDD\|238889	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has a conserved structural fold similar to those of other class II glutamine amidotransferases including glucosamine-fructose 6-phosphate synthase (GLMS or GFAT), glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase), asparagine synthetase B (AsnB), beta lactam synthetase (beta-LS) and glutamate synthase (GltS). The YafJ fold is also somewhat similar to the Ntn (N-terminal nucleophile) hydrolase fold of the proteasomal alpha and beta subunits.	2.02538e-67
NZ_CP018300.1\|WP_003900268.1\|1196715_1197609_+\|alpha/beta-hydrolase	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	1.05937e-52
NZ_CP018300.1\|WP_003901991.1\|1199261_1199984_+\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	3.72113e-20
NZ_CP018300.1\|WP_003405649.1\|1183383_1183950_+\|hypothetical-protein	gnl\|CDD\|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.38448e-17
NZ_CP018300.1\|WP_003405651.1\|1183946_1184342_+\|hypothetical-protein	gnl\|CDD\|238724	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain. This domain is believed to serve as a polysulfide binding and transferase domain in anaerobic gram-negative bacteria, functioning in oxidative phosphorylation with polysulfide-sulfur as a terminal electron acceptor. The active site contains the same conserved cysteine that is the catalytic residue in other Rhodanese Homology Domain proteins.	1.1419e-12
NZ_CP018300.1\|WP_003405625.1\|1176632_1178264_+\|long-chain-fatty-acid--CoA-ligase	gnl\|CDD\|341284	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles. This family includes fatty acyl-CoA synthetases that can activate medium-chain to long-chain fatty acids. They catalyze the ATP-dependent acylation of fatty acids in a two-step reaction. The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. The fatty acyl-CoA synthetases are responsible for fatty acid degradation as well as physiological regulation of cellular functions via the production of fatty acyl-CoA esters. The fatty acyl-CoA synthetase from Thermus thermophiles in this family catalyzes the long-chain fatty acid, myristoyl acid, while another member in this family, the AlkK protein identified from Pseudomonas oleovorans, targets medium chain fatty acids. This family also includes uncharacterized FACS proteins.	0
NZ_CP018300.1\|WP_003405716.1\|1191003_1192041_-\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|235533	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional.	0
NZ_CP018300.1\|WP_003405640.1\|1180831_1181689_+\|patatin-like-phospholipase-family-protein	gnl\|CDD\|224666	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only].	7.72024e-32
NZ_CP018300.1\|WP_003405645.1\|1182852_1183272_-\|hypothetical-protein	gnl\|CDD\|375114	pfam17301, LpqV, Putative lipoprotein LpqV. This is a family of cell surface proteins found in Mycobacterium with no known function.	3.05184e-46

>NZ_CP018300.1|WP_014585511.1|1184369_1186373_-|PE-family-protein
MSFVLVSPSQLMAAAADVAGIGSAISAANAAALAPTSVLAAAGADEVSAAVAALFSAHAGQYQQLGARAALFHEQFVQALTGAASAYASAKATNVEQQVLGLINAPTQALWGRPLIGNGADGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLIGNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGVGGVGGDGGQGGNGAGAGASGTKGGDAGAGGAGGAGGWIHGHGGAGGDGGAGGAGGQASPGAPGPPSQPGGAGGAGGAGGRGGDGGSAGWLSGNGGDAGNGGGGGTAGGAGNGGQFGGDGGTGGTGGTAGAGGNGGRGAVLFGHGGNAGHGGAGGNGAAAGAGGEHVVATAGKGGTGGVGGDGGGGGAGGGGGLLYGNGGAGGAGNSGGDGGTGLNAALGGNGGGGGVGGNAGAGGTGGSAGWLSGNGGAGGSGGSAGAGGAGGKGGDTPNGLAINPGIGGNGGDTGNAGNGGNGGSAARLFGGGGAGGAGGTGSTAGSGGSGGTNPPTGLQAAGGNGGSGHAGGHGGNGGGAGLLGGGGTGGNGGGGGQGGLGAAAGGVDGNGGNGGNGGKGGDAQLVGDGGNGGNGGKGGAGLIAGLDGAGGAGGTRGLIFGNAGTPGQ
>NZ_CP018300.1|WP_003405651.1|1183946_1184342_+|hypothetical-protein
MSRIDRVLEAARRRYRRLAADQVPEAARRGAVLVDIRPQAQRAREGEVPGALVIERNVLEWRCDPTSDARLPQAVDDDVEWVILCSEGYTSSLAAASLLDLGLHRATDVVGGYRALAAGGVLAELGGAVGG
>NZ_CP018300.1|WP_003405649.1|1183383_1183950_+|hypothetical-protein
MVMPLVTPTTAVPSPGPTRLRVADLLRATDQAADDVLGGRCDHLLPDGGVPQTQRWYTRIHGDEELDIWLISWVPGQPTELHDHGGSLGALTVLSGSLNEYRWDGRRLRRRRLDAGDQAGFPLGWVHDVVWAPRPIGGPDAAGMAVAPTLSVHAYSPPLTAMSYYEITERNTLRRQRTELTDQPEGSG
>NZ_CP018300.1|WP_003405645.1|1182852_1183272_-|hypothetical-protein
MRPSRYAPLLCAMVLALAWLSAVAGCSRGGSSKAGRSSSVAGTLPAGVVGVSPAGVTTRVDAPAESTEEEYYQACHAARLWMDAQPGSGESLIEPYLAVVQASPSGVAGSWHIRWAALTPARQAAVIVAARAAANAECG
>NZ_CP018300.1|WP_003405642.1|1181689_1182772_-|patatin-family-protein
MPAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDIVGIAGSSMGAVVGGVHAAGRLDEFAHWAKSLTQRTILRLLDPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPYTAVATDLLAGKSVWFQRGPLDAAIRASIAIPGVIAPHEVDGRLLADGGILDPLPMAPIAGVNADLTIAVSLNGSEAGPARDAEPNVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVLSRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPGLPKMGSFEVMNRTIDIAQSALARHTLAGYPADLLIEVPRSTCRSLEFHRAVEVIAVGRALATQALEAFEIDDDESAAATIEG
>NZ_CP018300.1|WP_003405640.1|1180831_1181689_+|patatin-like-phospholipase-family-protein
MTTRRALVLAGGGLAGIAWETGVLRGIADESPAAARLLLDSDVLVGTSAGATVAAQISSGCPLDTLYERQLAETSAEIDPGVDIDAITDLFLTAVTEPHISTRRRLQRIGAVALAVDTVPESVRRQVIAQRLPSHDWPDRVLRVTAIDIATGELVVFHRESNVALVDAVAASCSVPGAWPPVTIAGRRYMDGGVASSVNLGVADDCDAAVVLVPAGADAPSPFGGGAAAEIAAATGMVFAVFADDDSLAAFGPNPLDPLCRVNSAMAGRQQGRREAQAVARLLGV
>NZ_CP018300.1|WP_003405636.1|1179963_1180827_+|class-II-glutamine-amidotransferase
MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRRNPDGTGLGVFDEHHQPRLHKQPIAAWQDADFATEAHELTGTTFVAHVRYATTGSLDIRNTHPFLQDGRIFAHNGVVEGLDVLDERLREVGADDLVLGQTDSERVFALITASIRARDGNESAGLIDALRWLAANVPIYAVNVLLSTATDVWALRYPESHELYILDRRGDGAPEFHLRSKRIRAHSTHLRERSSVVFATEPMDDNPRWRLLDAGELVHVDAALRVNRSLVLPDPPRHPIRREDLSEPVLHAQHTSA
>NZ_CP018300.1|WP_003405633.1|1179456_1179930_+|SRPBCC-family-protein
MAKSVVVEQSRAIPVQSEDAFGGTLAAALPVICSHWYGLIPPIKEVRDQTGAWDSVGQARVITMVGGGRVREELTSVDPPRSFGYTLTDIKGPLAPLVALVEGKWSFAPADTGTTVTWQWTIHPRSALAAPVLPVFARMWRGYARGVLEKLSALLVG
>NZ_CP018300.1|WP_003405629.1|1178339_1179404_+|hypothetical-protein
MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGEIIGSPPLGVIATNSIDDVLALDADAVIYAPLLPSVDEVAALLRSGKNVVTPLGWFYPSEKEAAPLEVAAQAGNATLHGAGIGPGAVTELFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGPMQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEPGQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGPAGERYEIEVRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGIQSFFDLPLITGRAAPGLAR
>NZ_CP018300.1|WP_003405625.1|1176632_1178264_+|long-chain-fatty-acid--CoA-ligase
MYGTMQDFPLTITAIMRHGCGVHGRRTVTTATGEGYRHSSYRDVGQRAGQLANALRRLGVTGDQRVATFMWNNTEHLVTYFAVPSMGAVLHTLNIRLFPEQIAYVTNEAEDRVILVDLSLARLLAPVLPKLDTVHTVIAVGEGDTTPLREAGKTVLRFAELIDAESPDFGWPQIDENSAAAMCYTSGTTGNPKGVVYSHRSSFLHTMAACTTNGIGVGSSDKVLPIVPMFHANGWGLPYAALMAGADLVLPDRHLDARSLIHMVETLKPTLAGAVPTIWNDVMHYLEKDPDHDMSSLRLVACGGSAVPESLMRTFEDKHDVQIRQLWGMTETSPLATMAWPPPGTPDDQHWAFRITQGQPVCGVETRIVDDDGQVLPNDGNAVGEVEVRGPWIAGSYYGGRDESKFDSGWLRTGDVGRIDEQGFITLTDRAKDVIKSGGEWISSVELENCLIAHPDVLEAAVVGVPDERWQERPLAVVVVREGATVSAGDLRAFLADKVVRWWLPERWAFVDEIPRTSVGKYDKKAIRSRYAEGAYQITEVHT
>NZ_CP018300.1|WP_003405708.1|1188458_1190222_-|hypothetical-protein
MTEPAAATTTNASDEPATGAEQAVDTAATPQTPEPQPIRSTWWIRHYTFTGTAMGLVFVWFSMTPSLLPRGPLFQGLVSGICGAFGYGLGVFAVWLVRYMRSHNSSPPPPRWAWPPLIAVGAVGMVGMAVQFHVWQDDVRDLMGVEHLRWYDYPLAAALSLVVLFTLVEIGQFIRWLFRFLVGQVDRIAPFRVSAAIVVVLLVVLTITLLNGVVLKFAMNSMNSTFAAVNNEMNPDSAPPKTPLRSGGPGSLVSWESLGHQGRIFVHSGPTIADLTAFNGTPAVEPIRTYAGLNSADGIMATAELAARELARTGGLRRAVVAVATSTGTGWINEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARHAGEALFEAVDKLIRQLPESQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGPTFNNTVWNSLTANRDAGSPQWLPIYDDGRNVRFVARARDLQRPDAPWGRPRVVYLQHASDPIAWWTPRLLFREPDWLREQRGYDVLPQTRWIPVVTFVQVSADMAVATHVPDGHGHRYVATVADGWAAVLSPPGWTQQKTERLQPLLHANAKPFGS
>NZ_CP018300.1|WP_003405712.1|1190218_1190992_-|enoyl-CoA-hydratase
MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKRAPQFTHR
>NZ_CP018300.1|WP_003405716.1|1191003_1192041_-|enoyl-CoA-hydratase/isomerase-family-protein
MTGESHEVLTNVEGGVGFVTLNRPKAINSLNQTMVDLLATVLMSWEHEDAVHAVVLSGAGERGLCAGGDVVAVYHSARKDGVEARRFWRHEYLLNALIGRFAKPYVALMDGIVMGGGVGVSAHANTRVVTDTSKVAMPEVGIGFIPDVGGVYLLSRAPGALGLHAALTGAPFSGADAIALGFADHFVPHGDLDAFTQKIVTGGVESALAAHAVEPPPSTLAAQRDWIDECYAGDSVADIVAALRKQGGEPAVNASDLIASRSPIALSVTLQAVRRAAKLDTLEDVLIQDYRVSSASLRSHDLVEGIRAQLIDKDRNPNWSPATLDAITAADIEAYFEPVDDDLSF
>NZ_CP018300.1|WP_003405719.1|1192227_1193064_+|Bax-inhibitor-1/YccA-family-protein
MRETSNPVFRSLPKQRGGYAQFGTGTAQQGFPADPYLAPYREAKATRPLTIDDVVTKTGLTLAMLAGTAVVSYFLVASNVALAMPLTLVGALGGLALVLVATFGRKQDNPAIVLSYAALEGLFLGAISFVLANFTVASANAGVLIGEAILGTMGVFFGMLVVYKTGAIRVTPKFTRMVVAALFGVLVLMLGNLVLAMFNVGGGEGLGLRSPGPLGIIFSLVCIGIAAFSFLIDFDAADQMIRAGAPEKAAWGVALGLTVTLVWLYIEILRLLSYLQNE
>NZ_CP018300.1|WP_003405722.1|1193179_1194031_+|hypothetical-protein
MGAQPFIGSEALAAGLISWHELGKYYTAIMPNVYLDKRLKPSLRQRVIAAWLWSGRKGVIAGASASALHGAKWVDDHALVELIWRNARAPNGVRTKDELLLDGEVQRLCGLTVTTVERTAFDLGRRPPLGQAITRLDALANATDFKINDVRELARKHPHTRGLRQLDKALDLVDPGAQSPKETWLRLLLINAGFPRPSTQIPLLGVYGHPKYFLDMGWEDIMLAVEYDGEQHRLSRDQFVKDVERLEYIRRAGWTHIRVLADHKGPDVVRRVRQAWDTLTSRR
>NZ_CP018300.1|WP_003405724.1|1194104_1195322_-|acetyl-CoA-C-acetyltransferase
MPEAVIVSTARSPIGRAMKGSLVGMRPDDLAVQMVRAALDKVPALNPHQIDDLMMGCGLPGGESGFNIARVVAVALGYDFLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDAFISAGVETVSRFAKGNSDSWPDTKNPLFDGAQERSAAAAAGADEWHDPRTDQKLPDIYIAMGQTAENVAIMTGISREEQDRWGVRSQNRAEEAIKNGFFEREITPVTLPDGTTVSTDDGPRPGTTYEKVSELKPAFRPNGTVTAGNACPLNDGAAAVVITSDTKAKELGLTPLARIVSTGVSGLSPEIMGLGPIEASKKALERAGMAITDIDLVEINEAFAVQVLGSARELGIDEDKLNISGGAIALGHPFGMTGARITTTLLNNLQTYDKTFGLETMCVGGGQGMAMVIERLA
>NZ_CP018300.1|WP_003906506.1|1195374_1196319_-|SGNH/GDSL-hydrolase-family-protein
MPRRSTIALATAGALASTGTAYLGARNLLVGQATHARTVIPKSFDAPPRADGVYTRGGGPVQRWRREVPFDVHLMIFGDSTATGYGCASAEEVPGVLIARGLAEQTGKRIRLSTKAIVGATSKGVCGQVDAMFVVGPPPDAAVIMIGANDITALNGIGPSAQRLADCVRRLRTRGAVVVVGTCPDLGVITAIPQPLRALAHTRGVRLARAQTAAVKAAGGVPVPLGHLLAPKFRAMPELMFSADRYHPSAPAYALAADLLFLALRDALTEKLDILIHETPSRPGTATLEPGHTRHSMMSRLRRPRPARAVPTGG
>NZ_CP018300.1|WP_003900268.1|1196715_1197609_+|alpha/beta-hydrolase
MAVRPVLAVGSYLPHAPWPWGVIDQAARVLLPASTTVRAAVSLPNASAQLVRASGVLPADGTRRAVLYLHGGAFLTCGANSHGRLVELLSKFADSPVLVVDYRLIPKHSIGMALDDCHDGYRWLRLLGYEPEQIVLAGDSAGGYLALALAQRLQEVGEEPAALVAISPLLQLAKEHKQAHPNIKTDAMFPARAFDALDALVASAAARNQVDGEPEELYEPLEHITPGLPRTLIHVSGSEVLLHDAQLAAAKLAAAGVPAEVRVWPGQVHDFQVAASMLPEAIRSLRQIGEYIREATG
>NZ_CP018300.1|WP_003405730.1|1197665_1199060_+|cystathionine-beta-synthase
MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR
>NZ_CP018300.1|WP_003901991.1|1199261_1199984_+|RDD-family-protein
MTEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGAYPPPPPSAGGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQTSSCVTSISEYDVGQFCVSQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTIGSSIGKSVLKFKVVSETTGQPIGFGMSVVRQLAHFIDAIICFVGFLFPLWDAKRQTLADKIMTTVCVPI

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Crispr_ID: NZ_CP018300_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_7

1484788-1484907

Orphan

Consensus_repeat	Method
AACCCGCCGGTGCCGCCGGCACCGCCGGCG	PILER-CR

2 spacers

DinG

The CRISPR arrays of NZ_CP018300_7

>merge|NZ_CP018300|7|1484788-1484907|PILER-CR
AACCCGCCGGCGCCGCCGGCACCGCCATTGGAGAACAGCCCGCCGCCCCCGCCGGTGCCGCCGGTGCCACCGGTGCCCCCGTTGACGCTCAACCCGCCGGTGCCGCCGGCACCGCCGGCG

>NZ_CP018300|7|1|1484788-1484907|PILER-CR
AACCCGCCGGCGCCGCCGGCACCGCCATTG	GAGAACAGCCCGCCGCCCC
CGCCGGTGCCGCCGGTGCCACCGGTGCCCC	CGTTGACGCTCAACC
CGCCGGTGCCGCCGGCACCGCCGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003900313.1\|1473324_1474815_-\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
NZ_CP018300.1\|WP_003406879.1\|1481009_1481468_-\|methylmalonyl-CoA-epimerase	unknown	unknown	gnl\|CDD\|319912
NZ_CP018300.1\|WP_003406906.1\|1496357_1496663_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP018300.1\|WP_003898823.1\|1480678_1480975_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003898821.1\|1478210_1479914_-\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225025
NZ_CP018300.1\|WP_003898820.1\|1476590_1478198_-\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NZ_CP018300.1\|WP_003900321.1\|1494909_1496256_-\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236426
NZ_CP018300.1\|WP_003898829.1\|1496622_1497279_+\|DUF2017-domain-containing-protein	unknown	unknown	gnl\|CDD\|378185
NZ_CP018300.1\|WP_003406887.1\|1482857_1483772_+\|co-chaperone-YbbN	unknown	unknown	gnl\|CDD\|225660
NZ_CP018300.1\|WP_003406857.1\|1472830_1473328_-\|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|234860
NZ_CP018300.1\|WP_003898830.1\|1498337_1498778_+\|M67-family-metallopeptidase	unknown	unknown	gnl\|CDD\|163701
NZ_CP018300.1\|WP_023637385.1\|1481546_1482728_+\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
NZ_CP018300.1\|WP_003898827.1\|1492891_1494886_-\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP018300.1\|WP_003406897.1\|1488016_1490122_-\|alpha-1,4-glucan--maltose-1-phosphate-maltosyltransferase	unknown	unknown	gnl\|CDD\|200482
NZ_CP018300.1\|WP_003406910.1\|1498799_1499081_+\|MoaD/ThiS-family-protein	unknown	unknown	gnl\|CDD\|340594
NZ_CP018300.1\|WP_003900318.1\|1485813_1488009_-\|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl\|CDD\|235445
NZ_CP018300.1\|WP_003406872.1\|1479984_1480656_+\|endonuclease-NucS	unknown	unknown	gnl\|CDD\|235114
NZ_CP018300.1\|WP_003406908.1\|1497295_1498330_+\|P1-family-peptidase	unknown	unknown	gnl\|CDD\|225732
NZ_CP018300.1\|WP_003906575.1\|1474895_1476521_-\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NZ_CP018300.1\|WP_003901135.1\|1490260_1492852_+\|glycosyltransferase-family-1-protein	unknown	unknown	gnl\|CDD\|340852

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003900313.1\|1473324_1474815_-\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	4.18919e-73
NZ_CP018300.1\|WP_003406879.1\|1481009_1481468_-\|methylmalonyl-CoA-epimerase	gnl\|CDD\|319912	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE). MMCE, also called methylmalonyl-CoA racemase (EC 5.1.99.1) interconverts (2R)-methylmalonyl-CoA and (2S)-methylmalonyl-CoA. MMCE has been found in bacteria, archaea, and in animals. In eukaryotes, MMCE is an essential enzyme in a pathway that converts propionyl-CoA to succinyl-CoA, and is important in the breakdown of odd-chain length fatty acids, branched-chain amino acids, and other metabolites. In bacteria, MMCE participates in the reverse pathway for propionate fermentation, glyoxylate regeneration, and the biosynthesis of polyketide antibiotics. MMCE is closely related to glyoxalase I and type I extradiol dioxygenases.	4.30602e-49
NZ_CP018300.1\|WP_003406906.1\|1496357_1496663_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	1.75279e-41
NZ_CP018300.1\|WP_003901135.1\|1490260_1492852_+\|glycosyltransferase-family-1-protein	gnl\|CDD\|340852	cd04299, GT35_Glycogen_Phosphorylase-like, proteins similar to glycogen phosphorylase. This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism.	0
NZ_CP018300.1\|WP_003898821.1\|1478210_1479914_-\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|225025	COG2114, CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms].	4.8008e-44
NZ_CP018300.1\|WP_003898820.1\|1476590_1478198_-\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	3.71477e-42
NZ_CP018300.1\|WP_003900321.1\|1494909_1496256_-\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NZ_CP018300.1\|WP_003898829.1\|1496622_1497279_+\|DUF2017-domain-containing-protein	gnl\|CDD\|378185	pfam09438, DUF2017, Domain of unknown function (DUF2017). This is an alpha-helical domain found in gene neighborhoods that contain genes encoding ubiquitin, cysteine synthases and JAB peptidases.	6.82134e-72
NZ_CP018300.1\|WP_003406887.1\|1482857_1483772_+\|co-chaperone-YbbN	gnl\|CDD\|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	4.78114e-92
NZ_CP018300.1\|WP_003406857.1\|1472830_1473328_-\|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl\|CDD\|234860	PRK00901, PRK00901, methylated-DNA--protein-cysteine methyltransferase; Provisional.	1.27922e-67
NZ_CP018300.1\|WP_003898830.1\|1498337_1498778_+\|M67-family-metallopeptidase	gnl\|CDD\|163701	cd08070, MPN_like, Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding). This family contains archaeal and bacterial MPN (also known as Mov34, PAD-1, JAMM, JAB, MPN+)-like domains. These domains contain the signature JAB1/MPN/Mov34 metalloenzyme (JAMM) motif, EXnHS/THX7SXXD, which is involved in zinc ion coordination and provides the active site for isopeptidase activity for the release of ubiquitin from ubiquitinated proteins (thus having deubiquitinating (DUB) activity) that are tagged for degradation. The JAMM proteins likely hydrolyze ubiquitin conjugates in a manner similar to thermolysin, in which the zinc-polarized aqua ligand serves as the nucleophile, compared with the classical DUBs that do so with a cysteine residue in the active site.	3.44799e-41
NZ_CP018300.1\|WP_023637385.1\|1481546_1482728_+\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP018300.1\|WP_003898827.1\|1492891_1494886_-\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	2.71968e-166
NZ_CP018300.1\|WP_003406897.1\|1488016_1490122_-\|alpha-1,4-glucan--maltose-1-phosphate-maltosyltransferase	gnl\|CDD\|200482	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins. GlgE is a (1,4)-a-D-glucan:phosphate a-D-maltosyltransferase, involved in a-glucan biosynthesis in bacteria. It is also an anti-tuberculosis drug target. GlgE isoform I from Streptomyces coelicolor has the same catalytic and very similar kinetic properties to GlgE from Mycobacterium tuberculosis. GlgE from Streptomyces coelicolor forms a homodimer with each subunit comprising five domains (A, B, C, N, and S) and 2 inserts. Domain A is a catalytic alpha-amylase-type domain that along with domain N, which has a beta-sandwich fold and forms the core of the dimer interface, binds cyclodextrins. Domain A, B, and the 2 inserts define a well conserved donor pocket that binds maltose. Cyclodextrins competitively inhibit the binding of maltooligosaccharides to the S. coelicolor enzyme, indicating that the hydrophobic patch overlaps with the acceptor binding site. This is not the case in M. tuberculosis GlgE because cyclodextrins do not inhibit this enzyme, despite acceptor length specificity being conserved. Domain C is hypothesized to help stabilize domain A and could be involved in substrate binding. Domain S is a helix bundle that is inserted within the N domain and it plays a role in the dimer interface and interacts directly with domain B. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP018300.1\|WP_003406910.1\|1498799_1499081_+\|MoaD/ThiS-family-protein	gnl\|CDD\|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	1.00786e-47
NZ_CP018300.1\|WP_003900318.1\|1485813_1488009_-\|1,4-alpha-glucan-branching-protein-GlgB	gnl\|CDD\|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NZ_CP018300.1\|WP_003406872.1\|1479984_1480656_+\|endonuclease-NucS	gnl\|CDD\|235114	PRK03298, PRK03298, endonuclease NucS.	2.59655e-178
NZ_CP018300.1\|WP_003406908.1\|1497295_1498330_+\|P1-family-peptidase	gnl\|CDD\|225732	COG3191, DmpA, L-aminopeptidase/D-esterase [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.07624e-109
NZ_CP018300.1\|WP_003906575.1\|1474895_1476521_-\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	7.32396e-42

>NZ_CP018300.1|WP_003406887.1|1482857_1483772_+|co-chaperone-YbbN
MTRPRPPLGPAMAGAVDLSGIKQRAQQNAAASTDADRALSTPSGVTEITEANFEDEVIVRSDEVPVVVLLWSPRSEVCVDLLDTLSGLAAAAKGKWSLASVNVDVAPRVAQIFGVQAVPTVVALAAGQPISSFQGLQPADQLSRWVDSLLSATAGKLKGAASSEESTEVDPAVAQARQQLEDGDFVAARKSYQAILDANPGSVEAKAAIRQIEFLIRATAQRPDAVSVADSLSDDIDAAFAAADVQVLNQDVSAAFERLIALVRRTSGEERTRVRTRLIELFELFDPADPEVVAGRRNLANALY
>NZ_CP018300.1|WP_023637385.1|1481546_1482728_+|acetyl-CoA-C-acetyltransferase
MTTSVIVAGARTPIGKLMGSLKDFSASELGAIAIKGALEKANVPASLVEYVIMGQVLTAGAGQMPARQAAVAAGIGWDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLMNSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDMFTRSEQDEYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQFTEDEGIRANTTAAALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEIGAHGVVAGPDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALASIRELGLNPQIVNVNGGAIAVGHPLGMSGTRITLHAALQLARRGSGVGVAALCGAGGQGDALILRAG
>NZ_CP018300.1|WP_003406879.1|1481009_1481468_-|methylmalonyl-CoA-epimerase
MMTTDQVHARHMLATSLVTGLDHVGIAVADLDVAIEWYHDHLGMILVHEEINDDQGIREALLAVPGSAAQIQLMAPLDESSVIAKFLDKRGPGIQQLACRVSDLDAMCRRLRSQGVRLVYETARRGTANSRINFIHPKDAGGVLIELVEPAP
>NZ_CP018300.1|WP_003898823.1|1480678_1480975_+|hypothetical-protein
MARRRKPLHRQRPEPPSWALRRVEAGPDGHEYEVRPVAAARAVKTYRCPGCDHEIRSGTAHVVVWPTDLPQAGVDDRRHWHTPCWANRATRGPTRKWT
>NZ_CP018300.1|WP_003406872.1|1479984_1480656_+|endonuclease-NucS
MRLVIAQCTVDYIGRLTAHLPSARRLLLFKADGSVSVHADDRAYKPLNWMSPPCWLTEESGGQAPVWVVENKAGEQLRITIEGIEHDSSHELGVDPGLVKDGVEAHLQALLAEHIQLLGEGYTLVRREYMTAIGPVDLLCRDERGGSVAVEIKRRGEIDGVEQLTRYLELLNRDSVLAPVKGVFAAQQIKPQARILATDRGIRCLTLDYDTMRGMDSGEYRLF
>NZ_CP018300.1|WP_003898821.1|1478210_1479914_-|adenylate/guanylate-cyclase-domain-containing-protein
MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILVTNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARALRWAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVIGVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTAIFDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLSGDLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERHVAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAPNRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVNEAARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASPVQQLQMPAQSADIVGGALGDHQTHTIYRGAHPTD
>NZ_CP018300.1|WP_003898820.1|1476590_1478198_-|adenylate/guanylate-cyclase-domain-containing-protein
MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT
>NZ_CP018300.1|WP_003906575.1|1474895_1476521_-|adenylate/guanylate-cyclase-domain-containing-protein
MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVTANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQALRWAIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFIPRFLFAVSFCGVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMAMFEMVLLNLTRMQFATGVLIISMVTLVLGFILMWILAWLTATPVRVVRAALRRVERGELRTNLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERHVAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAPNRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVNEAARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKPVGLTKPRR
>NZ_CP018300.1|WP_003900313.1|1473324_1474815_-|DNA-3-methyladenine-glycosylase-2-family-protein
MHDDFERCYRAIQSKDARFDGWFVVAVLTTGVYCRPSCPVRPPFARNVRFLPTAAAAQGEGFRACKRCRPDASPGSPEWNVRSDVVARAMRLIADGTVDRDGVSGLAAQLGYTIRQLERLLQAVVGAGPLALARAQRMQTARVLIETTNLPFGDVAFAAGFSSIRQFNDTVRLACDGTPTALRARAAARFESATASAGTVSLRLPVRAPFAFEGVFGHLAATAVPGCEEVRDGAYRRTLRLPWGNGIVSLTPAPDHVRCLLVLDDFRDLMTATARCRRLLDLDADPEAIVEALGADPDLRAVVGKAPGQRIPRTVDEAEFAVRAVLAQQVSTKAASTHAGRLVAAYGRPVHDRHGALTHTFPSIEQLAEIDPGHLAVPKARQRTINALVASLADKSLVLDAGCDWQRARGQLLALPGVGPWTAEVIAMRGLGDPDAFPASDLGLRLAAKKLGLPAQRRALTVHSARWRPWRSYATQHLWTTLEHPVNQWPPQEKIA
>NZ_CP018300.1|WP_003406857.1|1472830_1473328_-|methylated-DNA--[protein]-cysteine-S-methyltransferase
MIHYRTIDSPIGPLTLAGHGSVLTNLRMLEQTYEPSRTHWTPDPGAFSGAVDQLNAYFAGELTEFDVELDLRGTDFQQRVWKALLTIPYGETRSYGEIADQIGAPGAARAVGLANGHNPIAIIVPCHRVIGASGKLTGYGGGINRKRALLELEKSRAPADLTLFD
>NZ_CP018300.1|WP_003900318.1|1485813_1488009_-|1,4-alpha-glucan-branching-protein-GlgB
MSRSEKLTGEHLAPEPAEMARLVAGTHHNPHGILGAHEYDDHTVIRAFRPHAVEVVALVGKDRFSLQHLDSGLFAVALPFVDLIDYRLQVTYEGCEPHTVADAYRFLPTLGEVDLHLFAEGRHERLWEVLGAHPRSFTTADGVVSGVSFAVWAPNAKGVSLIGEFNGWNGHEAPMRVLGPSGVWELFWPDFPCDGLYKFRVHGADGVVTDRADPFAFGTEVPPQTASRVTSSDYTWGDDDWMAGRALRNPVNEAMSTYEVHLGSWRPGLSYRQLARELTDYIVDQGFTHVELLPVAEHPFAGSWGYQVTSYYAPTSRFGTPDDFRALVDALHQAGIGVIVDWVPAHFPKDAWALGRFDGTPLYEHSDPKRGEQLDWGTYVFDFGRPEVRNFLVANALYWLQEFHIDGLRVDAVASMLYLDYSRPEGGWTPNVHGGRENLEAVQFLQEMNATAHKVAPGIVTIAEESTPWSGVTRPTNIGGLGFSMKWNMGWMHDTLDYVSRDPVYRSYHHHEMTFSMLYAFSENYVLPLSHDEVVHGKGTLWGRMPGNNHVKAAGLRSLLAYQWAHPGKQLLFMGQEFGQRAEWSEQRGLDWFQLDENGFSNGIQRLVRDINDIYRCHPALWSLDTTPEGYSWIDANDSANNVLSFMRYGSDGSVLACVFNFAGAEHRDYRLGLPRAGRWREVLNTDATIYHGSGIGNLGGVDATDDPWHGRPASAVLVLPPTSALWLTPA
>NZ_CP018300.1|WP_003406897.1|1488016_1490122_-|alpha-1,4-glucan--maltose-1-phosphate-maltosyltransferase
MSGRAIGTETEWWVPGRVEIDDVAPVVSCGVYPAKAVVGEVVPVSAAVWREGHEAVAATLVVRYLGVRYPHLTDRPRARVLPTPSEPQQRVKPLLIPMTSGQEPFVFHGQFTPDRVGLWTFRVDGWGDPIHTWRHGLIAKLDAGQGETELSNDLLVGAVLLERAATGVPRGLRDPLLAAAAALRTPGDPVTRTALALTPEIEELLADYPLRDLVTRGEQFGVWVDRPLARFGAWYEMFPRSTGGWDDDGNPVHGTFATAAAELPRIAGMGFDVVYLPPIHPIGKVHRKGRNNSPTAAPTDVGSPWAIGSDEGGHDTVHPSLGTIDDFDDFVSAARDLGMEVALDLALQCAPDHPWAREHRQWFTELPDGTIAYAENPPKKYQDIYPLNFDNDPEGLYDEVLRVVQHWVNHGVKFFRVDNPHTKPPNFWAWLIAQVKTVDPDVLFLSEAFTPPARQYGLAKLGFTQSYSYFTWRTTKWELTEFGNQIAELADYRRPNLFVNTPDILHAVLQHNGPGMFAIRAVLAATMSPAWGMYCGYELFEHRAVREGSEEYLDSEKYELRPRDFASALDQGRSLQPFITRLNIIRRLHPAFQQLRTIHFHHVDNDALLAYSKFDPATGDCVLVVVTLNAFGPEEATLWLDMAALGMEDYDRFWVRDEITGEEYQWGQANYIRIDPARAVAHIINMPAVPYESRNTLLRRR
>NZ_CP018300.1|WP_003901135.1|1490260_1492852_+|glycosyltransferase-family-1-protein
MKALRRFTVRAHLPERLAALDQLSTNLRWSWDKPTQDLFAAIDPALWEQCGHDPVALLGAVNPARLDELALDAEFLGALDELAADLNDYLSRPLWYQEQQDAGVAAQALPTGIAYFSLEFGVAEVLPNYSGGLGILAGDHLKSASDLGVPLIAVGLYYRSGYFRQSLTADGWQHETYPSLDPQGLPLRLLTDANGDPVLVEVALGDNAVLRARIWVAQVGRVPLLLLDSDIPENEHDLRNVTDRLYGGDQEHRIKQEILAGIGGVRAIRAYTAVEKLTPPEVFHMNEGHAGFLGIERIRELVTDAGLDFDTALTVVRSSTVFTTHTPVPAGIDRFPLEMVQRYVNDQRGDGRSRLLPGLPADRIVALGAEDDPAKFNMAHMGLRLAQRANGVSLLHGRVSRAMFNELWAGFDPDEVPIGSVTNGVHAPTWAAPQWLQLGRELAGSDSLREPVVWQRLHQVDPAHLWWIRSQLRSMLVEDVRARLRQSWLERGATDAELGWIATAFDPNVLTVGFARRVPTYKRLTLMLRDPDRLEQLLLDEQRPIQLIVAGKSHPADDGGKALIQQVVRFADRPQVRHRIAFLPNYDMSMARLLYWGCDVWLNNPLRPLEACGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADENRRDDLEAGALYDLLAQAVAPKFYERDERGVPQRWVEMVRHTLQTLGPKVLASRMVRDYVEHYYAPAAQSFRRTAGAQFDAARELADYRRRAEEAWPKIEIADVDSTGLPDTPLLGSQLTLTATVRLAGLRPNDVTVQGVLGRVDAGDVLMDPVTVEMAHTGTGDGGYEIFSTTTPLPLAGPVGYTVRVLPRHPMLAASNELGLVTLA
>NZ_CP018300.1|WP_003898827.1|1492891_1494886_-|ATP-dependent-DNA-helicase
MSESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYLVPAIIRALCDDAPVVVSTATIALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLCLNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTAWASTTVSGDRDDLKPGVGDRSWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEHRLLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHDARPGRIDCLDDEMATYLSALRDAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRILASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAELLATQVFARATTVLTSATLTIGGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIAELITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFGTLSLWQGVDVPGPSLSLVLIDRIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLLAQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPFWQTTNATQVRAALRRLARADAKAH
>NZ_CP018300.1|WP_003900321.1|1494909_1496256_-|nicotinate-phosphoribosyltransferase
MGPPPAARRREGEPDNQDPAGLLTDKYELTMLAAALRDGSANRPTTFEVFARRLPTGRRYGVVAGTGRLLEALPQFRFDADACELLAQFLDPATVRYLREFRFRGDIDGYAEGELYFPGSPVLSVRGSFAECVLLETLVLSIFNHDTAIASAAARMVSAAGGRPLIEMGSRRTHERAAVAAARAAYIAGFAASSNLAAQRRYGVPAHGTAAHAFTMLHAQHGGPTELAERAAFRAQVEALGPGTTLLVDTYDVTTGVANAVAAAGAELGAIRIDSGELGVLARQAREQLDRLGATRTRIVVSGDLDEFSIAALRGEPVDSYGVGTSLVTGSGAPTANMVYKLVEVDGVPVQKRSSYKESPGGRKEALRRSRATGTITEELVHPAGRPPVIVEPHRVLTLPLVRAGQPVADTSLAAARQLVASGLRSLPADGLKLAPGEPAIPTRTIPA
>NZ_CP018300.1|WP_003406906.1|1496357_1496663_+|ATP-dependent-Clp-protease-adapter-ClpS
MAVVSAPAKPGTTWQRESAPVDVTDRAWVTIVWDDPVNLMSYVTYVFQKLFGYSEPHATKLMLQVHNEGKAVVSAGSRESMEVDVSKLHAAGLWATMQQDR
>NZ_CP018300.1|WP_003898829.1|1496622_1497279_+|DUF2017-domain-containing-protein
MPPVCGRRCSRTGEIRGYSGSIVRRWKRVETRDGPRFRSSLAPHEAALLKNLAGAMIGLLDDRDSSSPSDELEEITGIKTGHAQRPGDPTLRRLLPDFYRPDDLDDDDPTAVDGSESFNAALRSLHEPEIIDAKRVAAQQLLDTVPDNGGRLELTESDANAWIAAVNDLRLALGVMLEIGPRGPERLPGNHPLAAHFNVYQWLTVLQEYLVLVLMGSR
>NZ_CP018300.1|WP_003406908.1|1497295_1498330_+|P1-family-peptidase
MNSITDVGGIRVGHYQRLDPDASLGAGWACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDPANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAVIFDLPVGGWNCRPTADFGYSACAAAGVDVAVGTVGVGVGARAGALKGGVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGEFALRAPPAEQIAALAQLSSPLGAFNTPFNTTIGVIACDAALSPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAVAVPPEAGVPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYRDMFPGAFGS
>NZ_CP018300.1|WP_003898830.1|1498337_1498778_+|M67-family-metallopeptidase
MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPTFYRLDSGEQLKVWRAMEDADEVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDPHRHELRSYRIVDGAVTEEPVNVVEQY
>NZ_CP018300.1|WP_003406910.1|1498799_1499081_+|MoaD/ThiS-family-protein
MNVTVSIPTILRPHTGGQKSVSASGDTLGAVISDLEANYSGISERLMDPSSPGKLHRFVNIYVNDEDVRFSGGLATAIADGDSVTILPAVAGG

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Crispr_ID: NZ_CP018300_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_8

1566525-1567596

Orphan

Consensus_repeat	Method
CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	CRISPRCasFinder

15 spacers

The CRISPR arrays of NZ_CP018300_8

>merge|NZ_CP018300|8|1566525-1567596|CRISPRCasFinder
CCCCCGGTCCCGCCGACGCCGCCGCCCCCGCCGTTGCCGGGGGTGCCATCGTTGCCGGCCCCACCGTTTCCGCCGGCGCCGCCGCCCCCGCCGTTGCCGATTAGGACGGCGGCCCCACCGTTTCCGCCGGTCCCGCCGTTGCCGCCGGTACCGTCCTCGCCGGCGGTGCCGCCCTTTCCGCCGGTCCCGCCGGTCCCGGCGTCGCCGATCAGGCCGGCGGCACCGCCTCGCCCGCCGGTCCCGCCGGCGCCGCCCTTGCCGAACACGCCGAAGCCGTCGCCGCCCTTGCCGCCGGTGCCGCCGGTGCCGCCGGTGCCGTAGAGTTGTCCGCCGTTGCCACCGGCCCCGCCGGCACCACCAATTCCGCCATTGCCGTCGGGCCCCTGGGCGCTGTGCCCGCCGGCCCCGCCGGTGCCGCCGTGGCCAATCAGACCGGCGGACCCGCCGGCTCCGCCAGCACCGCCAAGACCGTTCGGACTGGTGACGGTCCCGCCTGCCCCCCGGTGCCGCCGTTGCCAATGAGTTGCCCACCAGCGCCGCCGGCTCCACCGGCGCCGCCGCCCTGGCCACGGATATCACCGCCGTTGCCGCCGGCACCGCCGTCGCCGATCAGCCAGGCATTGCCACCGGCCCCGCCGGCGCCGCTAATTGCGCCTTGCCCGCCGTTGCCGCCGGCACCGCCGTTGCCGATGAGCCCGCCGGTACCGCCGGCACCGCCCGCGCCCCCGAAGTTATTCTCCCCGACTTTGCCTCCAACCCCAGTTTGCCCGCCGCGCCCGCCGGCCCCGCCGCTGCCCGACAGGCCGCGGCCGTCGCCGCCGGTGCCGCCGGCCCCGCCGTTGCCTCCTGAGCTGACGCCGGTTCCGCCCTGCCCGCCGTGTCCGCCGGCGCCGCCGTCGCCGTGCAGCCAGCCACCACCGCCACCGGCGCCGCCGATACCCCCCGTGCCGCCGTCGCCGGACTTGCCGCCACCGACCCCCCCTTGCCCGCCGGTGCCGCCGGACCCTCCGCTGCCCCACAATCCGGCGGCGCCGCCGGCACCGCCGGCACCGCCGACACCACCGGGGTCGCC

>NZ_CP018300|8|6|1566525-1567596|CRISPRCasFinder
CCCCCGGTCCCGCCGACGCCGCCGCCCCCGCC	GTTGCCGGGGGTGCCATCGTTGCCGGCC
CCACCGTTTCCGCCGGCGCCGCCGCCCCCGCC	GTTGCCGATTAGGACGGCGGCC
CCACCGTTTCCGCCGGTCCCGCCGTTGCCGCC	GGTACCGTCCTCGCCGGCGGTG
CCGCCCTTTCCGCCGGTCCCGCCGGTCCCGGC	GTCGCCGATCAGGCCGGCGGCA
CCGCCTCGCCCGCCGGTCCCGCCGGCGCCGCC	CTTGCCGAACACGCCGAAGCCGTCG
CCGCCCTTGCCGCCGGTGCCGCCGGTGCCGCC	GGTGCCGTAGAGTTGTCCGCCGTTGCCACCGGCCCCGCCGGCACCACCAATTCCGCCATTGCCGTCGGGCCCCTGG
GCGCTGTGCCCGCCGGCCCCGCCGGTGCCGCC	GTGGCCAATCAGACCGGCGGAC
CCGCCGGCTCCGCCAGCACCGCCAAGACCGTT	CGGACTGGTGACGGTCCCGCCTGCCCCCCGGTGCCGCCGTTGCCAATGAGTTGC
CCACCAGCGCCGCCGGCTCCACCGGCGCCGCC	GCCCTGGCCACGGATATCACCGCCGTTGCCGCCGGCACCGCCGTCGCCGATCAGC
CAGGCATTGCCACCGGCCCCGCCGGCGCCGCT	AATTGCGCCTTGCCCGCCGTTGCCGCCGGCA
CCGCCGTTGCCGATGAGCCCGCCGGTACCGCC	GGCACCGCCCGCGCCCCCGAAGTTATTCTCCCCGACTTTGCCTCCAACCCCAGTTTGC
CCGCCGCGCCCGCCGGCCCCGCCGCTGCCCGA	CAGGCCGCGGCCGTCGCCGCCGGTGCCGCCGGCCCCGCCGTTGCCTCCTGAGCTGACGCCGGTT
CCGCCCTGCCCGCCGTGTCCGCCGGCGCCGCC	GTCGCCGTGCAGCCAGCCACCACCGCCACCGGCG
CCGCCGATACCCCCCGTGCCGCCGTCGCCGGA	CTTGCCGCCACCGACCCCCCCTTGC
CCGCCGGTGCCGCCGGACCCTCCGCTGCCCCA	CAATCCGGCGGCGCCGCCGGCA
CCGCCGGCACCGCCGACACCACCGGGGTCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003407272.1\|1568848_1569106_-\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|279710
NZ_CP018300.1\|WP_003898861.1\|1568450_1568852_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350308
NZ_CP018300.1\|WP_003407295.1\|1574929_1575412_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP018300.1\|WP_003407297.1\|1575483_1576308_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP018300.1\|WP_003407260.1\|1563923_1565309_-\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NZ_CP018300.1\|WP_003407240.1\|1558288_1558606_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003407285.1\|1571951_1573919_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|237844
NZ_CP018300.1\|WP_003898859.1\|1559780_1561037_+\|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	unknown	unknown	gnl\|CDD\|235513
NZ_CP018300.1\|WP_003407257.1\|1562448_1563927_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NZ_CP018300.1\|WP_003407292.1\|1573936_1574761_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP018300.1\|WP_003407230.1\|1556108_1557728_+\|PPE-family-protein-PPE20	unknown	unknown	gnl\|CDD\|227938
NZ_CP018300.1\|WP_003407225.1\|1555803_1556112_+\|PE-family-protein	unknown	unknown	gnl\|CDD\|376422
NZ_CP018300.1\|WP_003407282.1\|1571268_1571871_+\|lysoplasmalogenase	unknown	unknown	gnl\|CDD\|226237
NZ_CP018300.1\|WP_003407264.1\|1565386_1566421_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP018300.1\|WP_003900336.1\|1576504_1577443_+\|methionyl-tRNA-formyltransferase	unknown	unknown	gnl\|CDD\|234567
NZ_CP018300.1\|WP_003407276.1\|1569188_1570148_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_CP018300.1\|WP_003407248.1\|1559432_1559765_+\|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl\|CDD\|188073
NZ_CP018300.1\|WP_003900331.1\|1558740_1559367_+\|guanylate-kinase	unknown	unknown	gnl\|CDD\|234719
NZ_CP018300.1\|WP_003900333.1\|1561164_1562376_+\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_CP018300.1\|WP_003407279.1\|1570172_1571135_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003407272.1\|1568848_1569106_-\|CopG-family-transcriptional-regulator	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	7.93081e-06
NZ_CP018300.1\|WP_003898861.1\|1568450_1568852_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350308	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.0663e-47
NZ_CP018300.1\|WP_003407295.1\|1574929_1575412_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.03006e-24
NZ_CP018300.1\|WP_003407297.1\|1575483_1576308_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.66024e-22
NZ_CP018300.1\|WP_003407260.1\|1563923_1565309_-\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	3.46688e-73
NZ_CP018300.1\|WP_003407225.1\|1555803_1556112_+\|PE-family-protein	gnl\|CDD\|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	6.65327e-12
NZ_CP018300.1\|WP_003407285.1\|1571951_1573919_+\|primosomal-protein-N'	gnl\|CDD\|237844	PRK14873, PRK14873, primosomal protein N'.	0
NZ_CP018300.1\|WP_003407292.1\|1573936_1574761_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.4474e-23
NZ_CP018300.1\|WP_003407257.1\|1562448_1563927_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	7.312e-122
NZ_CP018300.1\|WP_003407230.1\|1556108_1557728_+\|PPE-family-protein-PPE20	gnl\|CDD\|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	2.43157e-75
NZ_CP018300.1\|WP_003898859.1\|1559780_1561037_+\|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	gnl\|CDD\|235513	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated.	0
NZ_CP018300.1\|WP_003407282.1\|1571268_1571871_+\|lysoplasmalogenase	gnl\|CDD\|226237	COG3714, COG3714, Predicted membrane protein [Function unknown].	2.43759e-45
NZ_CP018300.1\|WP_003407264.1\|1565386_1566421_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.2925e-21
NZ_CP018300.1\|WP_003900336.1\|1576504_1577443_+\|methionyl-tRNA-formyltransferase	gnl\|CDD\|234567	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed.	5.56225e-154
NZ_CP018300.1\|WP_003407276.1\|1569188_1570148_-\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	7.78908e-92
NZ_CP018300.1\|WP_003407248.1\|1559432_1559765_+\|DNA-directed-RNA-polymerase-subunit-omega	gnl\|CDD\|188073	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit. This small component of highly purified E. coli RNA polymerase is not required for transcription, but acts in assembly and is present in stochiometric amounts. The trusted cutoff excludes archaeal homologs but captures some organellar sequences. [Transcription, DNA-dependent RNA polymerase].	1.81185e-20
NZ_CP018300.1\|WP_003900331.1\|1558740_1559367_+\|guanylate-kinase	gnl\|CDD\|234719	PRK00300, gmk, guanylate kinase; Provisional.	8.01602e-101
NZ_CP018300.1\|WP_003900333.1\|1561164_1562376_+\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_CP018300.1\|WP_003407279.1\|1570172_1571135_-\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	6.43916e-88

>NZ_CP018300.1|WP_003407264.1|1565386_1566421_+|AraC-family-transcriptional-regulator
MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDPDAVVGALDEITAVRRLLARLPDDAGIGIDVGSRFALTHFGLFGFAVMSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRGFFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVHDVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGITALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEARSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
>NZ_CP018300.1|WP_003407260.1|1563923_1565309_-|cytochrome-P450
MATATTQRPLKGPAKRMSTWTMTREAITIGFDAGDGFLGRLRGSDITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNSTFARRHLRGLVGLMIDPIADVTAALVPGAQFDMHQSMVETTLRVVANALFSQDFGPLVQSMHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREMQEITLTLDRAINSVIDRRLAEPTNSADLLNVLLSADGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRFLRCPTDRPRCAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGRRR
>NZ_CP018300.1|WP_003407257.1|1562448_1563927_-|NAD(P)/FAD-dependent-oxidoreductase
MMPDYHALIVGAGFSGIGAAIKLDRAGFSDYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGEITARFLISACGILTVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGIIGTGASAVQVIPEMAPIVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRIPGGKAVHRLLSQAFVEATFPIAAHYFAVFPLAKHMESAGRRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVATTDGASHEIDVLVLATGFKVLDTDSIPTYAVTGTGGASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVPLRPTTTVEAYWRSRRFDLGDYRISS
>NZ_CP018300.1|WP_003900333.1|1561164_1562376_+|methionine-adenosyltransferase
MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI
>NZ_CP018300.1|WP_003898859.1|1559780_1561037_+|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC
MVDHKRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSGEPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLARAAAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIAGHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIKKGVEGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLRRKGCDLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAIVTFLAGCSS
>NZ_CP018300.1|WP_003407248.1|1559432_1559765_+|DNA-directed-RNA-polymerase-subunit-omega
MSISQSDASLAAVPAVDQFDPSSGASGGYDTPLGITNPPIDELLDRVSSKYALVIYAAKRARQINDYYNQLGEGILEYVGPLVEPGLQEKPLSIALREIHADLLEHTEGE
>NZ_CP018300.1|WP_003900331.1|1558740_1559367_+|guanylate-kinase
MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNLHFSVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDLQARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVSLLVGTAPGSP
>NZ_CP018300.1|WP_003407240.1|1558288_1558606_+|hypothetical-protein
MALPQLTDEQRAAALEKAAAARRARAELKDRLKRGGTNLTQVLKDAESDEVLGKMKVSALLEALPKVGKVKAQEIMTELEIAPTRRLRGLGDRQRKALLEKFGSA
>NZ_CP018300.1|WP_003407230.1|1556108_1557728_+|PPE-family-protein-PPE20
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQASADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSRSALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYDDYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAITGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYLVGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGARASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
>NZ_CP018300.1|WP_003407225.1|1555803_1556112_+|PE-family-protein
MTLRVVPESLAGASAAIEAVTARLAAAHAAAAPFIAAVIPPGSDSVSVCNAVEFSVHGSQHVAMAAQGVEELGRSGVGVAESGASYAARDALAAASYLSGGL
>NZ_CP018300.1|WP_003898861.1|1568450_1568852_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MILVDSDVLIAHLRGVVAARDWLVSARKDGPLAISVVSTAELIGGMRTAERREVWRLLASFRVQPATEVIARRAGDMMRRYRRSHNRIGLGDYLIAATADVQDLQLATLNVWHFPMFEQLKPPFAVPGHRPRA
>NZ_CP018300.1|WP_003407272.1|1568848_1569106_-|CopG-family-transcriptional-regulator
MKRTNIYLDEEQTASLDKLAAQEGVSRAELIRLLLNRALTTAGDDLASDLQAINDSFGTLRHLDPPVRRSGGREQHLAQVWRATS
>NZ_CP018300.1|WP_003407276.1|1569188_1570148_-|alpha/beta-hydrolase
MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLKTPPELLPELRIEERTVGYDGLTDIPVRVYWPPVVRDNLPVVVYYHGGGWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALRWVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGGPPLVFQLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTMLPTTLAPGNADLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSNEPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA
>NZ_CP018300.1|WP_003407279.1|1570172_1571135_-|alpha/beta-hydrolase
MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDDGIEAVRQRLRDLPRQPVHPELRVVDLAIDGPAGPIGTRIYWPPTCPDQAEAPVVLYFHGGGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAATRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGGPPIVFQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPAPMAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQTLVHGYVGYAGVVPAATEATNRGLVALRVVLHG
>NZ_CP018300.1|WP_003407282.1|1571268_1571871_+|lysoplasmalogenase
MLQPAFKASMAVLLAAAAVAHPIGRERRWLVPALLLSATGDWLLAIPWWTWAFVFGLGAFLLAHLCFIGALLPLARQAAPSRGRVAAVVAMCVASAGLLVWFWPHLGKDNLTIPVTVYIVALSAMVCTALLARLPTIWTAVGAVCFAASDSMIGIGRFILGNEALAVPIWWSYAAAEILITAGFFFGREVPDNAAAPTDS
>NZ_CP018300.1|WP_003407285.1|1571951_1573919_+|primosomal-protein-N'
MLSVPHLDRDFDYLVPAEHSDDAQPGVRVRVRFHGRLVDGFVLERRSDSDHHGKLGWLDRVVSPEPVLTTEIRRLVDAVAARYAGTRQDVLRLAVPARHARVEREITTAPGRPVVAPVDPSGWAAYGRGRQFLAALADSRAARAVWQALPGELWADRFAEAAAQTVRAGRTVLAIVPDQRDLDTLWQAATALVDEHSVVALSAGLGPEARYRRWLAALRGSARLVIGTRSAVFAPLSELGLVMVWADADDSLAEPRAPYPHAREVAMLRAHQARCAALIGGYARTAEAHALVRSGWAHDVVAPRPEVRARSPRVVALDDSGYDDARDPAARTARLPSIALRAARSALQSGAPVLVQVPRRGYIPSLACGRCRAIARCRSCTGPLSLQGAGSPGAVCRWCGRVDPTLRCVRCGSDVVRAVVVGARRTAEELGRAFPGTAVITSAGDTLVPQLDAGPALVVATPGAEPRAPGGYGAALLLDSWALLGRQDLRAAEDALWRWMTAAALVRPRGAGGVVTVVAESSIPTVQSLIRWDPVGHAEAELAARTEVGLPPSVHIAALDGPAGTVTALLEAARLPDPDRLQADLLGPVDLPPGVRRPAGIPADAPVIRMLLRVCREQGLELAASLRRGIGVLSARQTRQTRSLVRVQIDPLHIG
>NZ_CP018300.1|WP_003407292.1|1573936_1574761_-|class-I-SAM-dependent-methyltransferase
MTVYTPTSERQAPATTHRQMWALGDYAAIAEELLAPLGPILVSTSGIRRGDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARAAAAGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVCRRGGKISTLNWTPEGFYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVSGLFRDHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSPECVATLDAEITELCREYLCDGVMQWEYLIFTARKC
>NZ_CP018300.1|WP_003407295.1|1574929_1575412_+|MarR-family-transcriptional-regulator
MMPTEYPATAEESVDVITDALLTASRLLVAISAHSIAQVDENITIPQFRTLVILSNHGPINLATLATLLGVQPSATGRMVDRLVGAELIDRLPHPTSRRELLAALTKRGRDVVRQVTEHRRTEIARIVEQMAPAERHGLVRALTAFTEAGGEPDARYEIE
>NZ_CP018300.1|WP_003407297.1|1575483_1576308_-|class-I-SAM-dependent-methyltransferase
MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMAPLGPILVAAAGIGPGVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARAAQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQAAADELVRVCRPGGTIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSALWGREAYVTGLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIGDNAVLAAELDRQLVELAAQYLSDGVMEWEYLLLTAEKR
>NZ_CP018300.1|WP_003900336.1|1576504_1577443_+|methionyl-tRNA-formyltransferase
MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPSPVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLLAVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPIYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPADGVSVAPKITVANARVRWDLPAAVVERRIRAVTPNPGAWTLIGDLRVKLGPVHLDAAHRPSKPLPPGGIHVERTSVWIGTGSEPVRLGQIQPPGKKLMNAADWARGARLDLAARAT

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Crispr_ID: NZ_CP018300_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_9

1631148-1631374

Orphan

Consensus_repeat	Method
CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP018300_9

>merge|NZ_CP018300|9|1631148-1631374|PILER-CR
CGCCGTCGCCGCCGGCGCCGCCCTGGCCGCCGTTGCCGCCGCTATTGCCTTTGCCACCGACTGCGCCCGAATCGCTCGCGTTCGTCCCTGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGACCAGCCCGCCATGGCCGCCGGGTCCGCCGTTGGCGCCGTTGGTGCCCGCGGTGGTGGCGTTGGCGCCGTTGCCGCCGGCACCGCCGTTGCCGCCG

>NZ_CP018300|9|2|1631148-1631374|PILER-CR
CGCCGTCGCCGCCGGCGCCGCCCTGGCCGCCGTTGCCGCCGCTATTG	CCTTTGCCACCGACTGCGCCCGAATCGCTCGCGTTCGTCCCTGCGGCGCCGTTGG
CGCCGTTGCCGCCGGCGCCGCCGTTGCCGACCAGCCCGCCATGGCCG	CCGGGTCCGCCGTTGGCGCCGTTGGTGCCCGCGGTGGTGGCGTTGGCGC
CGTTGCCGCCGGCACCGCCGTTGCCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003407451.1\|1622395_1624498_-\|transketolase	unknown	unknown	gnl\|CDD\|223100
NZ_CP018300.1\|WP_003904629.1\|1632901_1634167_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP018300.1\|WP_003407437.1\|1618752_1619664_-\|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	unknown	unknown	gnl\|CDD\|213538
NZ_CP018300.1\|WP_003407484.1\|1641562_1644103_+\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NZ_CP018300.1\|WP_003900341.1\|1635200_1636064_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003407475.1\|1637057_1637843_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|272861
NZ_CP018300.1\|WP_003898882.1\|1629561_1630488_+\|protoheme-IX-farnesyltransferase	unknown	unknown	gnl\|CDD\|235293
NZ_CP018300.1\|WP_003407433.1\|1618012_1618756_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|376480
NZ_CP018300.1\|WP_055371749.1\|1624936_1629160_-\|PE-family-protein	unknown	unknown	gnl\|CDD\|376422
NZ_CP018300.1\|WP_003407466.1\|1636013_1636946_-\|heme-A-synthase	unknown	unknown	gnl\|CDD\|224528
NZ_CP018300.1\|WP_003407422.1\|1616509_1616995_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176862
NZ_CP018300.1\|WP_003407462.1\|1634194_1635181_-\|quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|176189
NZ_CP018300.1\|WP_003407487.1\|1644099_1645293_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP018300.1\|WP_003407479.1\|1638936_1640712_-\|membrane-protein	unknown	unknown	gnl\|CDD\|274589
NZ_CP018300.1\|WP_003407477.1\|1637839_1638781_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP018300.1\|WP_003407419.1\|1614093_1616394_+\|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	unknown	unknown	gnl\|CDD\|273110
NZ_CP018300.1\|WP_003912809.1\|1621257_1622379_-\|transaldolase	unknown	unknown	gnl\|CDD\|235117
NZ_CP018300.1\|WP_003902080.1\|1640759_1641566_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225222
NZ_CP018300.1\|WP_009937558.1\|1617426_1617540_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003407443.1\|1619716_1621261_-\|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235579

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003407451.1\|1622395_1624498_-\|transketolase	gnl\|CDD\|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NZ_CP018300.1\|WP_003904629.1\|1632901_1634167_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.28507e-98
NZ_CP018300.1\|WP_003407462.1\|1634194_1635181_-\|quinone-oxidoreductase	gnl\|CDD\|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.18575e-173
NZ_CP018300.1\|WP_003407484.1\|1641562_1644103_+\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.06993e-131
NZ_CP018300.1\|WP_003407475.1\|1637057_1637843_-\|ABC-transporter-permease	gnl\|CDD\|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	2.1257e-66
NZ_CP018300.1\|WP_003898882.1\|1629561_1630488_+\|protoheme-IX-farnesyltransferase	gnl\|CDD\|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	1.94453e-135
NZ_CP018300.1\|WP_003407419.1\|1614093_1616394_+\|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	gnl\|CDD\|273110	TIGR00509, Trimethylamine-N-oxide_reductase_1, molybdopterin guanine dinucleotide-containing S/N-oxide reductases. This enzyme family shares sequence similarity and a requirement for a molydenum cofactor as the only prosthetic group. The form of the cofactor is a single molybdenum atom coordinated by two molybdopterin guanine dinucleotide molecules. Members of the family include biotin sulfoxide reductase, dimethylsulfoxide reductase, and trimethylamine-N-oxide reductase, although a single member may show all those activities and related activities; it may not be possible to resolve the primary function for members of this family by sequence comparison alone. A number of similar molybdoproteins in which the N-terminal region contains a CXXXC motif and may bind an iron-sulfur cluster are excluded from this set, including formate dehydrogenases and nitrate reductases. Also excluded is the A chain of a heteromeric, anaerobic DMSO reductase, which also contains the CXXXC motif.	0
NZ_CP018300.1\|WP_055371749.1\|1624936_1629160_-\|PE-family-protein	gnl\|CDD\|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.87382e-33
NZ_CP018300.1\|WP_003407466.1\|1636013_1636946_-\|heme-A-synthase	gnl\|CDD\|224528	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones].	9.53658e-61
NZ_CP018300.1\|WP_003407422.1\|1616509_1616995_-\|hypothetical-protein	gnl\|CDD\|176862	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	1.36448e-06
NZ_CP018300.1\|WP_003407487.1\|1644099_1645293_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	2.43694e-97
NZ_CP018300.1\|WP_003407479.1\|1638936_1640712_-\|membrane-protein	gnl\|CDD\|274589	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein. This model represents a family of hydrophobic and presumed membrane proteins found in the Actinobacteria. The genes encoding these proteins are syntenically associated with (found proximal to) genes of carotene biosynthesis ususally including phytoene synthase (crtB), phytoene dehydrogenase (crtI) and geranylgeranyl pyrophosphate synthase (ispA).	2.25454e-61
NZ_CP018300.1\|WP_003407477.1\|1637839_1638781_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.38211e-90
NZ_CP018300.1\|WP_003407433.1\|1618012_1618756_-\|6-phosphogluconolactonase	gnl\|CDD\|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	1.17344e-94
NZ_CP018300.1\|WP_003912809.1\|1621257_1622379_-\|transaldolase	gnl\|CDD\|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NZ_CP018300.1\|WP_003902080.1\|1640759_1641566_+\|transcriptional-regulator	gnl\|CDD\|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	4.83711e-80
NZ_CP018300.1\|WP_003407437.1\|1618752_1619664_-\|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	gnl\|CDD\|213538	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA. The opcA gene is found immediately downstream of zwf, the glucose-6-phosphate dehydrogenase (G6PDH) gene, in a number of species, including Mycobacterium tuberculosis, Streptomyces coelicolor, Nostoc punctiforme, and Synechococcus sp. PCC 7942. In the latter, disruption of opcA was shown to block assembly of G6PDH into active oligomeric forms. [Protein fate, Protein folding and stabilization].	1.38424e-154
NZ_CP018300.1\|WP_003407443.1\|1619716_1621261_-\|glucose-6-phosphate-dehydrogenase	gnl\|CDD\|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0

>NZ_CP018300.1|WP_003898882.1|1629561_1630488_+|protoheme-IX-farnesyltransferase
MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
>NZ_CP018300.1|WP_055371749.1|1624936_1629160_-|PE-family-protein
MSLVIVTPETVAAAALDVARIGSSIGAANAAAAGSTTSVLAAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQALLGRPLIGDGAAGAPGTGQAGGAGGILWGNGGAGGSGAPGQVGGAGGAAGLFGTGGAGGAGGAGAAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGGHGGVGGAAGLLGVGGHGGAGGHGAEGVAGAAGEDLSPHGTSGGVGGDAGDGGTGGRGGWLAGAGGAGGAGGVGGTGGAGGAGFSRALIVAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGAGGTGGAGGVGGDGGAGGPGNQAFNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGGAGGAGGKGGNGGNGATGATGLNGLGAGADGTDGGKGGNGGAGGGGGAGGQGGKALAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNGGSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGANATVAGGAGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNGGAGGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPGAKGGDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGLAGDGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHGFTPTSGGDGGDGGNGGNSQVVGGNGGDGGNGGNGGSAGTGGNGGRGGDGAFGGMSANATNPGENGPNGNPGGNGGAGGAGGAGLNGGNGGAGGNGGLGGFGGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGGNGGQGVVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGHGAASGGNGGPGGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNGGRGGNGGQGLTGAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGGRGGDAGRGGDAGLGGSSGPGGTPGDWGTGGTGGTGGTGGQGANGGLTGGRGGTGGNGGNGNTGGTGGAGGTGGTGHNGSQPGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPFGTGTGGTGGHGGQGGGGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
>NZ_CP018300.1|WP_003407451.1|1622395_1624498_-|transketolase
MTTLEEISALTRPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGLVARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSADLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDGTDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTVSARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN
>NZ_CP018300.1|WP_003912809.1|1621257_1622379_-|transaldolase
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYATYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ
>NZ_CP018300.1|WP_003407443.1|1619716_1621261_-|glucose-6-phosphate-dehydrogenase
MKPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWAAHGTPDAYEAGTWGPESSLEMLRRTGREWRRP
>NZ_CP018300.1|WP_003407437.1|1618752_1619664_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA
MIVDLPDTTTTAVNKKLDELREKIGAVAMGRVLTLIIAPDSEAMLEESIEAANDASHEHPSRIIVTMRGDPYADRPRLDAQLRVGADAGAGEFVVLRLSGPLAGHADSVVIPFLLPDIPVVAWWPDIAPAVPAQDALGKLAIRRITDATNAIDPLSAIKSRLAGYGAGDTDLAWSRITYWRALLTSAVDQPPHEPIESALVSGLKTEPALDVLAGWLASRIEGPVRRAVGELKVELVRNSETIVLSRPQEGITATLTRTGKPDALVPLARRVTGECLAEDLRRLDPDEIYCAALEGIKKVQYR
>NZ_CP018300.1|WP_003407433.1|1618012_1618756_-|6-phosphogluconolactonase
MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKLPS
>NZ_CP018300.1|WP_009937558.1|1617426_1617540_-|hypothetical-protein
MFLGQATIWAGWAILCGRLPVATGLAVFVGIWFVASP
>NZ_CP018300.1|WP_003407422.1|1616509_1616995_-|hypothetical-protein
MVGYAEPVLIERQSVVAAPAEQVWQRVVTPEGINDELRPWMTMSVPRGAKGMTVDTVPIGAPIGRAWLRLFGVLPFDYDRLSIAELEPGRRFREDSTMLSMRQWQHERTVTPEGDTKTIVRDRITFQTRAGLRFAAPLIAAGLRALFGHRHRRLQRHFAQG
>NZ_CP018300.1|WP_003407419.1|1614093_1616394_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase
MQVYTSATHWGVFTARVHGGDIAAVAALASDTNPAPQLQNLPGAVRHRSRIANPAVRRGWLQHGPGPSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYGSSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGAALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHPDRDYVGRYRARGGRLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGLAYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLAAGDLRDLARRMAEHRTLITTSLSLQRIEHGEQTVWMAATLAAMLGQIGLPGGGFGHGYSSNGVGNPPLACGLPALPQGNNPVSTFIPVAAISELLQRPGQRLAYNGRLLELPDIKCVYWAGGNPFHHHQNLPRLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDFAASKTNPTLIAMPAMVPPYANARDDYHTFSALAHRLGFGKQFTEGRSAREWLEHMYDKWSAELDFPVPSFAEFWRTGRLELPTRTGLTWLADFRADPAAHPLGTPSGRIEIFSDTVDAFALPDCAGHPTWYEPSEWLGGPRAARYPLHLIANQPRTRLHSQLDHGGASMASKIRGREPIRIHPDDAAARELTDGDIVRVFNDRGACLAGVVIDDGLRPKVVQLSTGAWFDPADPRDPDSMCVHGNPNALSNDSGTSSLAHGSTGQHVLVQIERFTGELPPVRAHEPPRLA
>NZ_CP018300.1|WP_003904629.1|1632901_1634167_+|PucR-family-transcriptional-regulator
MALRETSPRIHELIREAARIALNPTQEWLDEFDRAILAANPSIAADPALATVVKRSNRAHLIHFAAANLRNPGAPVPANLGPEPLRMARDLVRVGLDALALDIYRIGQNVAWRRWTDIAFGLTSDPDELHELLDVPFRTANEFVDTTLAGITTEMQLERDKLTRDVPAERRKIVQLLIDGAPISREHAEARLGYPLDRSHTAAVIWGDQAQGDHSHLDRVADAFGHAGGCPHPLVVVAGAATRWVWVKDAPGFDIDLIHEVLHDIPDARIAIGATAPGIEGFRRSHRDALTTARMIIRLESPHRVAFFTDVEMVALLTENAEGADDFIQRTLGNLESASPALKTTLLTFINQQCNASRAARLLFTHRNTLMNRLETAQRLLPRPLADTTIHVAVALEAQQWREKQTSDPPAKKESNGTKMR
>NZ_CP018300.1|WP_003407462.1|1634194_1635181_-|quinone-oxidoreductase
MHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP
>NZ_CP018300.1|WP_003900341.1|1635200_1636064_+|hypothetical-protein
MKLARPDVFHPRVVLAGWPQQPAGDGDDAGLVAALRHRGLHAGWLSWDDPEIVHADLVILRATRDYPARLDEFLAWTTRVANLLNSRPVVAWNVERRYLRDLMDRGVPTVPGEVYVPGEPVRLPRKGQVFVGPTIGTGTRRCSARFAAEFVAQLHAAGQAVLVQPGGSGDETVLVFLGGEPSHAFTKQADTWRQTEPDFEIWDVGAAAVAGAAAQVGVDPGELLYARAHITGGSRDPRLLELQLVDPSLGWQWLDPDIRNLAQRDFALCVQSALERLGLGPFSHRRP
>NZ_CP018300.1|WP_003407466.1|1636013_1636946_-|heme-A-synthase
MPYDRAVSPSLRVQRVIAAIVILTQGGIAVTGAIVRVTASGLGCPTWPQCFPGSFTPVVVAEVPRVHQAVEFGNRMVTFAVVIAAALAVLVVTRARRRTEVLAYAWLMPVSTVVQAMIGGITVRTGLLWWTVAIHLLASMTMVWLAVLLYVKIGQPDDGVVHELVVSPLRALTALSALNLAAVLVTGTLVTAAGPHAGDRSPSRTVPRLKVEITTLVHMHSSLLVAYLALLIGLGFGLLAVGATRAILVRLAVLLALVATQAAVGTTQYFTGVPAALVAIHVAGAAAVTAATAALWASMGERAQPQPLQR
>NZ_CP018300.1|WP_003407475.1|1637057_1637843_-|ABC-transporter-permease
MTQTNRPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLLLTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAVAFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGWRPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAGFGALTLESNVIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVVLAVWGALAALAALRWFRFT
>NZ_CP018300.1|WP_003407477.1|1637839_1638781_-|ABC-transporter-ATP-binding-protein
MNRAPDTPEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQGGGGYPAARAGEMLDLVASYAANPLDPHWLLDTLGLTEAARTTYRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQIDVLATDMRVEQRSLEDVFLDLTGRKLRQ
>NZ_CP018300.1|WP_003407479.1|1638936_1640712_-|membrane-protein
MAARHHTLSWSIASLHGDEQAVGAPLTTTELTALARTRLFGATGTVLMAIGALGAGARPVVQDPTFGVRLLNLPSRIQTVSLTMTTTGAVMMALAWLMLGRFTLGRRRMSRGELDRTLLLWMLPLLIAPPMYSKDVYSYLAQSEIGRDGLDPYRVGPASGLGLGHVFTLSVPSLWRETPAPYGPLFLWIGRGISSLTGENIVAAVLCHRLVVLIGVTLIVWATPRLAQRCGVAEVSALWLGAANPLLIMHLVAGIHNEALMLGLMLTGVEFALRGLDMANTPRPSPETWRLGPATIRASRRPELGASPRAGASRAVKPRPEWGPLAMLLAGSILITLSSQVKLPSLLAMGFVTTVLAYRWGGNLRALLLAAAVMASLTLAIMAILGWASGLGFGWINTLGTANVVRSWMSPPTLLALGTGHVGILLGLGDHTTAVLSLTRAIGVLIITVMVCWLLLAVLRGRLHPIGGLGVALAVTVLLFPVVQPWYLLWAIIPLAAWATRPGFRVAAILATLIVGIFGPTANGDRFALFQIVDATAASAIIVILLIALTYTRLPWRPLAAEQVVTAAESASKTPATRRPTAAPDAYADST
>NZ_CP018300.1|WP_003902080.1|1640759_1641566_+|transcriptional-regulator
MTSTTLPHRASLVDRSTEFCHTDVVKIPAVSTTVPAAVSDGHTRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEAGDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLREIGGEEAVRTFARRRIDAILADVAPADGPDDAALEAAAERIATALSKAGYVATTTRVGGPIHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGTHVQRLATIVNGDCACTTHVPLSPAPSPRPPATSTEGASR
>NZ_CP018300.1|WP_003407484.1|1641562_1644103_+|Fe-S-cluster-assembly-protein-SufB
MTLTPEASKSVAQPPTQAPLTQEEAIASLGRYGYGWADSDVAGANAQRGLSEAVVRDISAKKNEPDWMLQSRLKALRIFDRKPIPKWGSNLDGIDFDNIKYFVRSTEKQAASWDDLPEDIRNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEAQGVIFLDTDTGLREHPDIFKEYFGTVIPAGDNKFSALNTAVWSGGSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADEGSYVHYVEGCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPLLAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGYYLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDNVGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYATVELRRPGGPGVIMGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDSYLAYGFAVHNCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARAEAGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEDQHQDTGAKMLHLAPNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTVSRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLTEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG
>NZ_CP018300.1|WP_003407487.1|1644099_1645293_+|Fe-S-cluster-assembly-protein-SufD
MTAPGLTAAVEGIAHNKGELFASFDVDAFEVPHGRDEIWRFTPLRRLRGLHDGSARATGSATITVSERPGVYTQTVRRGDPRLGEGGVPTDRVAAQAFSSFNSATLVTVERDTQVVEPVGITVTGPGEGAVAYGHLQVRIEELGEAVVVIDHRGGGTYADNVEFVVDDAARLTAVWIADWADDTVHLSAHHARIGKDAVLRHVTVMLGGDVVRMSAGVRFCGAGGDAELLGLYFADDGQHLESRLLVDHAHPDCKSNVLYKGALQGDPASSLPDAHTVWVGDVLIRAQATGTDTFEVNRNLVLTDGARADSVPNLEIETGEIVGAGHASATGRFDDEQLFYLRSRGIPEAQARRLVVRGFFGEIIAKIAVPEVRERLTAAIEHELEITESTEKTTVS

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Crispr_ID: NZ_CP018300_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_10

2071290-2071826

Orphan

Consensus_repeat	Method
GCCGCCGTNNCCGCCGNTGCC	CRT

9 spacers

The CRISPR arrays of NZ_CP018300_10

>merge|NZ_CP018300|10|2071290-2071826|CRT
TCCGCCCGTACCGCCGCTGCCGCCCGGCCCGCCAGAGTCGCCGGGCCCACCGTCGCCGCCGTCGCCGATCAACTGGGCGTAGCCGCCGTTACCGCCGGTGCCGGGGGTGCCGTCCCCGCTGACGCCGGCGGCGCCGCCATTGCCACCGTTGCCGATCAACCCGGCCGTGCCGCCGTTACCCCCGGTGCCGCCGGCGCCGGTGACGGGTACCGCGACTGAGGGAATCTGGGTTGGCCCACCGGAGCCGCCGGCGCCACCATTGCCGACCAGCAGCGCGCCGTTGCCTCCGTTCCCGCCACTGCCACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGCGCCTCCGGCGCCACCGTTGCCGATCAGCCCGACGGCGTTGCCGCCGTCGCCGCCGTGGCCTCGGAGAAAGCCGTCGGTTTGCACGCTGTTGCCGCCGTCGCCGCCGTTGCCGATCAGCGTCCCGCCGGTGCCGCCGTCGCCGCCGTTGCCATCGAAGAAGCTGAACCCGCCGTTACCGCCGTCGCCGAACATCCC

>NZ_CP018300|10|2|2071290-2071826|CRT
TCCGCCCGTACCGCCGCTGCC	GCCCGGCCCGCCAGAGTCGCCGGGCCCACCGTCGCCGCCGTCGCCGATCAACTGGGCGTA
GCCGCCGTTACCGCCGGTGCC	GGGGGTGCCGTCCCCGCTGACGCCGGCGGCGCCGCCATTGCCACCGTTGCCGATCAACCCGGCCGT
GCCGCCGTTACCCCCGGTGCC	GCCGGCGCCGGTGACGGGTACCGCGACTGAGGGAATCTGGGTTGGCCCACCGGA
GCCGCCGGCGCCACCATTGCC	GACCAGCAGCGCGCCGTT
GCCTCCGTTCCCGCCACTGCC	ACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGC
GCCTCCGGCGCCACCGTTGCC	GATCAGCCCGACGGCGTT
GCCGCCGTCGCCGCCGTGGCC	TCGGAGAAAGCCGTCGGTTTGCACGCTGTT
GCCGCCGTCGCCGCCGTTGCC	GATCAGCGTCCCGCCGGT
GCCGCCGTCGCCGCCGTTGCC	ATCGAAGAAGCTGAACCCGCCGTT
ACCGCCGTCGCCGAACATCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003901265.1\|2065885_2067919_-\|solute-binding-protein	unknown	unknown	gnl\|CDD\|238733
NZ_CP018300.1\|WP_003409284.1\|2077013_2078465_-\|NADP-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236453
NZ_CP018300.1\|WP_003409271.1\|2068038_2070264_-\|malate-synthase-G	unknown	unknown	gnl\|CDD\|235097
NZ_CP018300.1\|WP_003409298.1\|2078494_2079445_-\|M56-family-metallopeptidase	unknown	unknown	gnl\|CDD\|320685
NZ_CP018300.1\|WP_003899046.1\|2074000_2075368_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP018300.1\|WP_003409308.1\|2080923_2081238_+\|urease-subunit-beta	unknown	unknown	gnl\|CDD\|106171
NZ_CP018300.1\|WP_003899048.1\|2080153_2080576_+\|esterase	unknown	unknown	gnl\|CDD\|224961
NZ_CP018300.1\|WP_003899049.1\|2081237_2082971_+\|urease-subunit-alpha	unknown	unknown	gnl\|CDD\|237304
NZ_CP018300.1\|WP_003409258.1\|2063983_2065870_-\|serine-esterase	unknown	unknown	gnl\|CDD\|273375
NZ_CP018300.1\|WP_003900418.1\|2059159_2061985_+\|aminomethyl-transferring-glycine-dehydrogenase	unknown	unknown	gnl\|CDD\|235432
NZ_CP018300.1\|WP_003409242.1\|2057337_2057832_+\|bifunctional-nuclease-family-protein	unknown	unknown	gnl\|CDD\|376830
NZ_CP018300.1\|WP_003409254.1\|2062211_2063072_-\|haloalkane-dehalogenase	unknown	unknown	gnl\|CDD\|179554
NZ_CP018300.1\|WP_003409305.1\|2080624_2080927_+\|urease-subunit-gamma	unknown	unknown	gnl\|CDD\|376347
NZ_CP018300.1\|WP_003409244.1\|2058123_2058801_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133380
NZ_CP018300.1\|WP_003900419.1\|2072963_2074001_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP018300.1\|WP_003409301.1\|2079459_2079876_-\|transcriptional-regulator-BlaI	unknown	unknown	gnl\|CDD\|226207
NZ_CP018300.1\|WP_003409255.1\|2063112_2063979_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP018300.1\|WP_003409273.1\|2070539_2070935_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|224761
NZ_CP018300.1\|WP_003409276.1\|2070931_2071195_-\|antitoxin	unknown	unknown	unknown
NZ_CP018300.1\|WP_003900420.1\|2075541_2076978_-\|GuaB1-family-IMP-dehydrogenase-related-protein	unknown	unknown	gnl\|CDD\|181127

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003901265.1\|2065885_2067919_-\|solute-binding-protein	gnl\|CDD\|238733	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the members of this subgroup. All members of this subgroup however have a conserved MIDAS motif. .	3.79869e-39
NZ_CP018300.1\|WP_003409284.1\|2077013_2078465_-\|NADP-dependent-phosphogluconate-dehydrogenase	gnl\|CDD\|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NZ_CP018300.1\|WP_003899048.1\|2080153_2080576_+\|esterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	8.89234e-31
NZ_CP018300.1\|WP_003409298.1\|2078494_2079445_-\|M56-family-metallopeptidase	gnl\|CDD\|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	3.1451e-26
NZ_CP018300.1\|WP_003899046.1\|2074000_2075368_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	8.70643e-128
NZ_CP018300.1\|WP_003409308.1\|2080923_2081238_+\|urease-subunit-beta	gnl\|CDD\|106171	PRK13202, ureB, urease subunit beta; Reviewed.	3.42156e-64
NZ_CP018300.1\|WP_003899049.1\|2081237_2082971_+\|urease-subunit-alpha	gnl\|CDD\|237304	PRK13206, ureC, urease subunit alpha; Reviewed.	0
NZ_CP018300.1\|WP_003409258.1\|2063983_2065870_-\|serine-esterase	gnl\|CDD\|273375	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c., putative hydrolase, CocE/NonD family. This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP018300.1\|WP_003900418.1\|2059159_2061985_+\|aminomethyl-transferring-glycine-dehydrogenase	gnl\|CDD\|235432	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase.	0
NZ_CP018300.1\|WP_003409242.1\|2057337_2057832_+\|bifunctional-nuclease-family-protein	gnl\|CDD\|376830	pfam02577, DNase-RNase, Bifunctional nuclease. This family is a bifunctional nuclease, with both DNase and RNase activity. It forms a wedge-shaped dimer, with each monomer being triangular in shape. A large groove at the thick end of the wedge contains a possible active site.	1.28808e-61
NZ_CP018300.1\|WP_003409254.1\|2062211_2063072_-\|haloalkane-dehalogenase	gnl\|CDD\|179554	PRK03204, PRK03204, haloalkane dehalogenase; Provisional.	0
NZ_CP018300.1\|WP_003409305.1\|2080624_2080927_+\|urease-subunit-gamma	gnl\|CDD\|376347	pfam00547, Urease_gamma, Urease, gamma subunit. Urease is a nickel-binding enzyme that catalyzes the hydrolysis of urea to carbon dioxide and ammonia.	1.78898e-65
NZ_CP018300.1\|WP_003409244.1\|2058123_2058801_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	6.61772e-22
NZ_CP018300.1\|WP_003900419.1\|2072963_2074001_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.8319e-96
NZ_CP018300.1\|WP_003409301.1\|2079459_2079876_-\|transcriptional-regulator-BlaI	gnl\|CDD\|226207	COG3682, COG3682, Predicted transcriptional regulator [Transcription].	1.25443e-40
NZ_CP018300.1\|WP_003409255.1\|2063112_2063979_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.65147e-19
NZ_CP018300.1\|WP_003409273.1\|2070539_2070935_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|224761	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.16634e-21
NZ_CP018300.1\|WP_003409271.1\|2068038_2070264_-\|malate-synthase-G	gnl\|CDD\|235097	PRK02999, PRK02999, malate synthase G; Provisional.	0
NZ_CP018300.1\|WP_003900420.1\|2075541_2076978_-\|GuaB1-family-IMP-dehydrogenase-related-protein	gnl\|CDD\|181127	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein.	0

>NZ_CP018300.1|WP_003409276.1|2070931_2071195_-|antitoxin
MSKRLQVLLDPDEWEELREIARRHRTTVSEWVRRTLREAREREPRGDLDMKLRSVRAAARHEFPTADVEQMLEEIERGRGAEREGSR
>NZ_CP018300.1|WP_003409273.1|2070539_2070935_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MILVDSNIPMYLVGASHPHKLDAQRLLESALSGGERLVTDAEVLQEICHRYVAIKRREAIQPAFDAIIGVVDEVLPIERTDVEHARDALLRYQTLSARDALHIAVMAHHDITRLMSFDRGFDSYPGIKRLA
>NZ_CP018300.1|WP_003409271.1|2068038_2070264_-|malate-synthase-G
MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDELQAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSGVDAEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSVPLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIEILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLAAAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFEGIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRKGTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTAWVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDNNCQSILGYVVRWVDQGVGCSKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRASLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKARAAEKPAPSDRAGDDAAR
>NZ_CP018300.1|WP_003901265.1|2065885_2067919_-|solute-binding-protein
MGRHSKPDPEDSVDDLSDGHAAEQQHWEDISGSYDYPGVDQPDDGPLSSEGHYSAVGGYSASGSEDYPDIPPRPDWEPTGAEPIAAAPPPLFRFGHRGPGDWQAGHRSADGRRGVSIGVIVALVAVVVMVAGVILWRFFGDALSNRSHTAAARCVGGKDTVAVIADPSIADQVKESADSYNASAGPVGDRCVAVAVTSAGSDAVINGFIGKWPTELGGQPGLWIPSSSISAARLTGAAGSQAISDSRSLVISPVLLAVRPELQQALANQNWAALPGLQTNPNSLSGLDLPAWGSLRLAMPSSGNGDAAYLAGEAVAAASAPAGAPATAGIGAVRTLMGARPKLADDSLTAAMDTLLKPGDVATAPVHAVVTTEQQLFQRGQSLSDAENTLGSWLPPGPAAVADYPTVLLSGAWLSQEQTSAASAFARYLHKPEQLAKLARAGFRVSDVKPPSSPVTSFPALPSTLSVGDDSMRATLADTMVTASAGVAATIMLDQSMPNDEGGNSRLSNVVAALENRIKAMPPSSVVGLWTFDGREGRTEVPAGPLADPVNGQPRPAALTAALGKQYSSGGGAVSFTTLRLIYQEMLANYRVGQANSVLVITAGPHTDQTLDGPGLQDFIRKSADPAKPIAVNIIDFGADPDRATWEAVAQLSGGSYQNLETSASPDLATAVNIFLS
>NZ_CP018300.1|WP_003409258.1|2063983_2065870_-|serine-esterase
MTRRGGSDAAWYSAPDQRSAYPRYRGMRYSSCYVTMRDGVRIAIDLYLPAGLTSAARLPAILHQTRYYRSLQLRWPLRMLLGGKPLQHIAADKRRRRRFVASGYAWVDVDVRGSGASFGARVCEWSSDEIRDGAEIVDWIVRQPWCNGTVAALGNSYDGTSAELLLVNQHPAVRVIAPCFSLFDVYTDIAFPGGIHAAWFTDTWGRYNEALDRNALHEVVGWWAKLPVTGMQPVQEDRDRSLRDGAIAAHRGNYDVHQIAGSLTFRDDVSASDPYRGQPDARLEPIGTPIESGSINLISPHNYWRDVQASGAAIYSYSGWFDGGYAHAAIKRFLTVSTPGSHLILGPWNHTGGWRVDPLRGLSRPDFDHDGELLRFIDHHVKGADTGIGSEPPVHYFTMVENRWKSADTWPPPATTQSYYLSADRQLRPDAPDCDSGADEYVVDQTAGTGERSRWRSQVGIGGHVCYPDRKAQDAKLLTYTSAPLDHPLEVTGHVVVTLFITSTSSDGTFFVYLEDVDPRGRVAYITEGQLRAIHRRLSDGPPPYRQVVPYRTFASGDAWPLVPGEIARLTFDLLPTSYLFQPGHRIRIAIAGADASHFAILPGCAPTVRVYRSRMHASRIDLPVIQP
>NZ_CP018300.1|WP_003409255.1|2063112_2063979_+|alpha/beta-hydrolase
MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD
>NZ_CP018300.1|WP_003409254.1|2062211_2063072_-|haloalkane-dehalogenase
MSIDFTPDPQLYPFESRWFDSSRGRIHYVDEGTGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSERPSGFGYQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVRGVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAILRRNFFVERLIPAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREVPATLGTKPTLLIWGMKDVAFRPKTIIPRLSATFPDHVLVELPNAKHFIQEDAPDRIAAAIIERFG
>NZ_CP018300.1|WP_003900418.1|2059159_2061985_+|aminomethyl-transferring-glycine-dehydrogenase
MSDHSTFADRHIGLDSQAVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAEALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQPEISQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAARGPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGVIAQLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAFGTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAIARRVHAHAEAIAGALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVDADHVSVACDEATTDTHVAVVLDAFGVAAAAPAHTDIATRTSEFLTHPAFTQYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESITWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQGEYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCHDNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGLRAASLTAITSANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGITVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIGIRAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTAFRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA
>NZ_CP018300.1|WP_003409244.1|2058123_2058801_+|MerR-family-transcriptional-regulator
MTQLVTRARSARGSTLGEQPRQDQLDFADHTGTAGDGNDGAAAASGPVQPGLFPDDSVPDELVGYRGPSACQIAGITYRQLDYWARTSLVVPSIRSAAGSGSQRLYSFKDILVLKIVKRLLDTGISLHNIRVAVDHLRQRGVQDLANITLFSDGTTVYECTSAEEVVDLLQGGQGVFGIAVSGAMRELTGVIADFHGERADGGESIAAPEDELASRRKHRDRKIG
>NZ_CP018300.1|WP_003409242.1|2057337_2057832_+|bifunctional-nuclease-family-protein
MGEVRVVGIRVEQPQNQPVLLLREANGDRYLPIWIGQSEAAAIALEQQGVEPPRPLTHDLIRDLIAALGHSLKEVRIVDLQEGTFYADLIFDRNIKVSARPSDSVAIALRVGVPIYVEEAVLAQAGLLIPDESDEEATTAVREDEVEKFKEFLDSVSPDDFKAT
>NZ_CP018300.1|WP_003900419.1|2072963_2074001_-|HlyC/CorC-family-transporter
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
>NZ_CP018300.1|WP_003899046.1|2074000_2075368_-|HlyC/CorC-family-transporter
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
>NZ_CP018300.1|WP_003900420.1|2075541_2076978_-|GuaB1-family-IMP-dehydrogenase-related-protein
MRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPIPAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVTAPAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGVDVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGADNPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW
>NZ_CP018300.1|WP_003409284.1|2077013_2078465_-|NADP-dependent-phosphogluconate-dehydrogenase
MSSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVEITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSVGQRSAASGLASGKLGEQPADPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDITPGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPYFRGAVESAIDSWRRVVSTAAQLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTEVPV
>NZ_CP018300.1|WP_003409298.1|2078494_2079445_-|M56-family-metallopeptidase
MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSSFSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLVGARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVLDVAQPLAYCLPGVRSRVVVSEGTLTALADAEVAAILTHERAHLRARHDLVLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARALVACASGRAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLVVPTVALAVPWLTQLQRLFIA
>NZ_CP018300.1|WP_003409301.1|2079459_2079876_-|transcriptional-regulator-BlaI
MAKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQIRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALAELEAGHGNRPPAGAATET
>NZ_CP018300.1|WP_003899048.1|2080153_2080576_+|esterase
MQPSPDSPAPLNVTVPFDSELGLQFTELGPDGARAQLDVRPKLLQLTGVVHGGVYCAMIESIASMAAFAWLNSHGEGGSVVGVNNNTDFVRSISSGMVYGTAEPLHRGRRQQLWLVTITDDTDRVVARGQVRLQNLEARP
>NZ_CP018300.1|WP_003409305.1|2080624_2080927_+|urease-subunit-gamma
MRLTPHEQERLLLSYAAELARRRRARGLRLNHPEAIAVIADHILEGARDGRTVAELMASGREVLGRDDVMEGVPEMLAEVQVEATFPDGTKLVTVHQPIA
>NZ_CP018300.1|WP_003409308.1|2080923_2081238_+|urease-subunit-beta
MIPGEIFYGSGDIEMNAAALSRLQMRIINAGDRPVQVGSHVHLPQANRALSFDRATAHGYRLDIPAATAVRFEPGIPQIVGLVPLGGRREVPGLTLNPPGRLDR
>NZ_CP018300.1|WP_003899049.1|2081237_2082971_+|urease-subunit-alpha
MARLSRERYAQLYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGAPDTVITGAVIIDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVHLICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFAESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQPVLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF

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Crispr_ID: NZ_CP018300_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_11

2151803-2152022

Orphan

Consensus_repeat	Method
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018300_11

>merge|NZ_CP018300|11|2151803-2152022|CRISPRCasFinder
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAGCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTCGTTGTAGCTGGAATCGTCAACGACGGCACCGTCAACCCCGGCAAATCAA

>NZ_CP018300|11|7|2151803-2152022|CRISPRCasFinder
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	GCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTC
GTTGTAGCTGGAATCGTCAACGACGGCACCGTCAACCCCGGCAAATCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003409667.1\|2157055_2158171_+\|lipoprotein	unknown	unknown	gnl\|CDD\|224594
NZ_CP018300.1\|WP_003903680.1\|2144905_2146102_+\|isocitrate-lyase-subunit-B	unknown	unknown	gnl\|CDD\|225134
NZ_CP018300.1\|WP_003409577.1\|2143260_2143668_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003409684.1\|2161945_2162425_-\|MPT63-family-protein	unknown	unknown	gnl\|CDD\|370335
NZ_CP018300.1\|WP_003899082.1\|2154049_2154514_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NZ_CP018300.1\|WP_003900434.1\|2159538_2159919_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003899079.1\|2141426_2142431_-\|oxidoreductase-FadB	unknown	unknown	gnl\|CDD\|176236
NZ_CP018300.1\|WP_003409566.1\|2140045_2140639_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|224793
NZ_CP018300.1\|WP_003409685.1\|2162661_2163435_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225897
NZ_CP018300.1\|WP_003409574.1\|2142530_2143283_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293840
NZ_CP018300.1\|WP_003409686.1\|2163438_2164206_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|135631
NZ_CP018300.1\|WP_009937678.1\|2137228_2139451_-\|catalase/peroxidase-HPI	unknown	unknown	gnl\|CDD\|237891
NZ_CP018300.1\|WP_057114459.1\|2146271_2150300_-\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NZ_CP018300.1\|WP_003900433.1\|2158161_2159502_+\|lipase-LipD	unknown	unknown	gnl\|CDD\|365903
NZ_CP018300.1\|WP_003409680.1\|2160075_2161938_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|171527
NZ_CP018300.1\|WP_003409666.1\|2155512_2156784_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273654
NZ_CP018300.1\|WP_003899076.1\|2139488_2139932_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_CP018300.1\|WP_003900432.1\|2154611_2155475_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|153249
NZ_CP018300.1\|WP_003906697.1\|2143802_2144906_+\|isocitrate-lyase-family-protein	unknown	unknown	gnl\|CDD\|225134
NZ_CP018300.1\|WP_003409568.1\|2140721_2141327_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|224793

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003409667.1\|2157055_2158171_+\|lipoprotein	gnl\|CDD\|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	8.61879e-60
NZ_CP018300.1\|WP_003903680.1\|2144905_2146102_+\|isocitrate-lyase-subunit-B	gnl\|CDD\|225134	COG2224, AceA, Isocitrate lyase [Energy production and conversion].	1.12063e-87
NZ_CP018300.1\|WP_003899082.1\|2154049_2154514_-\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.38133e-21
NZ_CP018300.1\|WP_003409684.1\|2161945_2162425_-\|MPT63-family-protein	gnl\|CDD\|370335	pfam09167, DUF1942, Domain of unknown function (DUF1942). Members of this family of bacterial proteins assume a beta-sandwich structure consisting of two antiparallel beta-sheets similar to an immunoglobulin-like fold, with an additional small, antiparallel beta-sheet. The longer-stranded beta-sheet is made up of four antiparallel beta-strands. The shorter-stranded beta-sheet consists of five beta-strands, four of these beta-strands form an antiparallel beta-sheet. The exact function of this family of proteins is unknown, though a putative role includes involvement in host-bacterial interactions involved in endocytosis or phagocytosis, possibly during bacterial internalisation.	3.87872e-58
NZ_CP018300.1\|WP_003899079.1\|2141426_2142431_-\|oxidoreductase-FadB	gnl\|CDD\|176236	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.26124e-152
NZ_CP018300.1\|WP_003409566.1\|2140045_2140639_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	4.33831e-50
NZ_CP018300.1\|WP_003409685.1\|2162661_2163435_+\|hypothetical-protein	gnl\|CDD\|225897	COG3361, COG3361, Uncharacterized conserved protein [Function unknown].	4.52786e-127
NZ_CP018300.1\|WP_003409574.1\|2142530_2143283_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.95555e-42
NZ_CP018300.1\|WP_003409686.1\|2163438_2164206_-\|SDR-family-oxidoreductase	gnl\|CDD\|135631	PRK05867, PRK05867, SDR family oxidoreductase.	8.21275e-152
NZ_CP018300.1\|WP_009937678.1\|2137228_2139451_-\|catalase/peroxidase-HPI	gnl\|CDD\|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NZ_CP018300.1\|WP_057114459.1\|2146271_2150300_-\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.34088e-80
NZ_CP018300.1\|WP_003900433.1\|2158161_2159502_+\|lipase-LipD	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	7.07573e-54
NZ_CP018300.1\|WP_003409680.1\|2160075_2161938_+\|AMP-binding-protein	gnl\|CDD\|171527	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional.	0
NZ_CP018300.1\|WP_003409666.1\|2155512_2156784_-\|hypothetical-protein	gnl\|CDD\|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI\|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI\|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	4.7592e-11
NZ_CP018300.1\|WP_003899076.1\|2139488_2139932_-\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	4.92282e-41
NZ_CP018300.1\|WP_003900432.1\|2154611_2155475_+\|acyltransferase-family-protein	gnl\|CDD\|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	3.35135e-64
NZ_CP018300.1\|WP_003906697.1\|2143802_2144906_+\|isocitrate-lyase-family-protein	gnl\|CDD\|225134	COG2224, AceA, Isocitrate lyase [Energy production and conversion].	1.00107e-132
NZ_CP018300.1\|WP_003409568.1\|2140721_2141327_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	1.29998e-51

>NZ_CP018300.1|WP_057114459.1|2146271_2150300_-|PPE-family-protein
MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
>NZ_CP018300.1|WP_003903680.1|2144905_2146102_+|isocitrate-lyase-subunit-B
MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
>NZ_CP018300.1|WP_003906697.1|2143802_2144906_+|isocitrate-lyase-family-protein
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWASRSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWRPGRTTRA
>NZ_CP018300.1|WP_003409577.1|2143260_2143668_-|hypothetical-protein
MVLSRTSTGRVILVPTQLRFDRWFLPLAVPLGLGPKNSELWVGAGSLHVKMGWAFAADIPLTSITKAEATNARVYAAGVHFGFGRWLVNGSRKGLVALTIDPPEQAKMWKKSMTVRELWVSVTDPDALVTACTAK
>NZ_CP018300.1|WP_003409574.1|2142530_2143283_+|MBL-fold-metallo-hydrolase
MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
>NZ_CP018300.1|WP_003899079.1|2141426_2142431_-|oxidoreductase-FadB
MRAVVITKHGDPSVLQVRQRPDPPPPGPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGGYCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAAVQFAKAAKAEVHGTASPQKHQKLAEFGVDRAIDYRRDGWWQGLGPYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVDKVVLVP
>NZ_CP018300.1|WP_003409568.1|2140721_2141327_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG
>NZ_CP018300.1|WP_003409566.1|2140045_2140639_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MAHAFHRFALAILGLALPVALVAYGGNGDSRKAAPLAPKAAALGRSMPETPTGDVLTISSPAFADGAPIPEQYTCKGANIAPPLTWSAPFGGALVVDDPDAPREPYVHWIVIGIAPGAGSTADGETPGGGISLPNSSGQPAYTGPCPPAGTGTHHYRFTLYHLPAVPPLAGLAGTQAARVIAQAATMQARLIGTYEG
>NZ_CP018300.1|WP_003899076.1|2139488_2139932_-|transcriptional-repressor
MSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGAVRFALPDVSRQAVYDVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCSISDTSRSHP
>NZ_CP018300.1|WP_009937678.1|2137228_2139451_-|catalase/peroxidase-HPI
MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDIEEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLSWADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPDPMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVVWTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEHPEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAASSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAGHNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKRLPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKFVQDFVAAWDKVMNLDRFDVR
>NZ_CP018300.1|WP_003899082.1|2154049_2154514_-|SRPBCC-family-protein
MSGRKFSFEVTKTSSAPAATLFRLVTDGGNWATWAKPIVAQSSWARRGDPAPGGIGAIRKLGMWPVFVQEETVEYEQDRRHVYKLVGARTPVQDYFGEVVLTPNASGGTDLRWSGSFTEKVRGTGPVMRAALGGAVRFFAGQLVKAAEREAVRR
>NZ_CP018300.1|WP_003900432.1|2154611_2155475_+|acyltransferase-family-protein
MFPRWPQQAHNHEVSRADTVSVPRAPTQAEVAAVLRIMTPLRKVIKPKVYGIENVPTERALLVGNHNTLGLVDAPLLAAELWERGRIVRSLGDHAHFKIPGWRDALTRTGVVEGTREITSELMRRGELVMVFPGGAREVNKRKNERYKLVWKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEKLLGTKDGPALVRGVGLTPVPRPERQYYWFGEPIDTTEFMGQQADDNAARRVRERAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA
>NZ_CP018300.1|WP_003409666.1|2155512_2156784_-|hypothetical-protein
MVRLIPSLLAMATVLGGVIGCSAHQPPTPASGCRQLDAFLKWHHGVREFLQSAIDANSRCTGTADGSARKVAIFDWDNTVVKNDIGYATNYYMLQHSLVLQPANQDWHAASRYLTDAAANALSVACGKVVPAGKPLPTGSNALCANEILSLLDGETTTGQPAFVGNNVRRLAGPYAWSNALSAGYTAEELAGFADQAKKQNLAADVGATQQVGTQQVDGYIRVYPQMKDLIGTLQAHGIDTWVVSASPEPIVKVWAGEVGLDDQHVVGVRSVADQSGKLTAHLVGCGGVRDGDDSVMTYLDGKRCWANQVIFGVTGPQAFNQLAADRRQVLAAGDSNSDATFVGDATVVSLVINRNQDDLMCRAYDGLFTRGGKWAINPMFIDPLPQHAPYVCGEAFINPDGSKQPVLRNDGTPIPDQVDSVF
>NZ_CP018300.1|WP_003409667.1|2157055_2158171_+|lipoprotein
MDSTVTASIRRMLGLLAATLLLGGCTGQHTTRTAASTTYTPHIKASSQDVLDGAINADEPGCSAAVGVEGKVIWSGVRGIADLASGAKITTDTVFDIASVSKQFTATAILLLVEAGKLTLDDPISQYVPELPDWAQTVTVEQLMHQTSGIPDYVALLAARGYQVSDRTIEAEARQALAAAPELQFKPGTRFDYSNSNYLLLGEIVHRASGQPLPEFLSAEIFQPLGLAMVVDPVGKVPNKAVSYEKGTGGNRSEYRVGNPAWEQIGDGGIQTTPSQLARWADNYRTGSVGGLKLLEAQLAGAVETEPGGGDRYGAGIVSRADGTLDHAGAWAGFVTAFHISSDRRTSVAISCNTDKPDPVAMADALGRLWM
>NZ_CP018300.1|WP_003900433.1|2158161_2159502_+|lipase-LipD
MDVAGLPRLAAGTQAAIIHGMAQPPSLLTTDNGLPFGVQGACDSRFTGVIRAFAGLYPGRKFGGGALSVYIDGRQVVDVWTGWSDRQGKVPWTADTGAMVFSATKGLAATVIHRLVDRGLLSYDAPVAEYWPEFGANGKSEVTVSDVLRHRSGLAHLKGVDKDEVMDHLLMEQKLAAAPLDRQHGKLAYHAVTYGWLLSGLARAVTGKGMRELFREELARPLNTDGIHLGRPPADSPTKAAQTLLPQAKVPTPLLDFIAPKVAGLSFSGLLGAVYFPGILSLLQDDMPFLDGEVPAVNGVVTARALAKTYGALANDGVIDGTRLLSSQAVRGLTGKSELWPDLNLGLPFTYHQGYQSSPVPGLLEGYGHIGLGGTIGWADPETGSAFGYVHNRLLTLLLFDIGSFAGLAALLNSAVVAARRDDPLEVPHFGAPYSEPRHEQAASGA
>NZ_CP018300.1|WP_003900434.1|2159538_2159919_-|hypothetical-protein
MDPADVINPTSTRDAALARVLAYRQRVRARPLLIRATLAVVGGGLFVVSLPMIVLLPELGIPALLVAFRLLAVEAQWAVRAYAWTDWRFTQLREWFHRQVLVTRAAILVGLFLAAVALVWLLVYEF
>NZ_CP018300.1|WP_003409680.1|2160075_2161938_+|AMP-binding-protein
MNDGSRQELRVRSGLLQIEDCLDADGGIALPAGTTLISLIERNIKYVGDLVAYRYLDHARSAAGCALEVTWTQFGMRLAAIGAHVQRFAGPGDRVAILAPQGIDYVCGFYAAIKAGTVAVPLFAPELPGHAERLDTALRDSEPAVILTTAAAKNAVEGFLNNVPRLRKPTVLVIDQIPDREGELFVPVELDIDAVSHLQYTSGSTRPPVGVEITHRAVGTNLVQMILSIDLLNRNTHGVSWLPLYHDMGLSMIGFPAVYGGHSTLMSPTAFVRRPLRWIQALSEGSRTGRVVTAAPNFAYEWAAQRGLPAQGDDVDLSNVVLIIGSEPVSIDAVTTFNKAFAPYGLPRTAFKPSYGIAEATLLVATIDHAAEPTVVYLDPEQLGAGHATRVAPDAPNAVVHVSCGHVARSLWAVIVDPDTGPEAGAELPDGEIGEVWLQGDNVARGYWGRPEETRMTFGARLQSPLAEGSHADGSAIDDTWLRTGDLGVYLDGELYITGRIADLLTIDGRNHYPQDIEATAAEASPMVRRGYITAFTVPASDGDDRNQRLVIIAERAAGTSRSDPRPALDAIRAAVCNRHGLSVADLSFLPAGAIPRTTSGKLARQACRAQYLSGRLGVH
>NZ_CP018300.1|WP_003409684.1|2161945_2162425_-|MPT63-family-protein
MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIVAMNNGMEDLLIWEP
>NZ_CP018300.1|WP_003409685.1|2162661_2163435_+|hypothetical-protein
MTAIPGPSGAEPGESRALAGYPVTPPALPRPVIFDQRWTDLTFIHWPVLPESVAGSYPPGTRPDVFADGMTYVGLVPFRMSSTKLGTALPIPYVGTFPETNVRLYSIDNAGRHGVLFRSLETARLTVVPLTRIGLGIPYAWSRMRMMRSGKHITYHSVRRWPRRGLRSLLTITIGDLVEPTPLEVWLTARWGAHTRKAGRTWWVPNEHKPWPLRAAEIAELNDELIDASGVQPTGDRLRALFSPGVHARFGRPCVVQ
>NZ_CP018300.1|WP_003409686.1|2163438_2164206_-|SDR-family-oxidoreductase
MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAIAARHLDALEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAELGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVNSVSPGYILTELVEPYTEYQPLWEPKIPLGRLGRPEELAGLYLYLASEASSYMTGSDIVIDGGYTCP

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Crispr_ID: NZ_CP018300_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_12

3103398-3104752

TypeIII

II-B,III-A

Consensus_repeat	Method
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRT

18 spacers

cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6

The CRISPR arrays of NZ_CP018300_12

>merge|NZ_CP018300|12|3103398-3104752|PILER-CR,CRISPRCasFinder,CRT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAAGTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGACTGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGACATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGACCCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACTTGCGCGCACAACGCATCCGCCATCCACGGGGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGGACTTGATCGACGCGAACCTGTCTGACGCGAACCTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGGCTGGAAAAGGGCGCGGGGCAACCGCATCGTCAAGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGCGTTGTGGTCGTGTCGTGGAGCCTGTATTTCGCTGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCATTAGTTGGTGTTGTGATCGCTAAACGCCGGGGCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTATCCGCGGGAAGAGATCACGAATCCGGCGTCGAAGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACATGCTGAGCTGAGGCGCCGGATGATGGTGGTGCTGAAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGACAGGGTGCGGTGGTCGCTGATCGGCTCCCCGAGTTTCCGTCCCCTCTCGGTTTGAACCGCCCCGGTGA

>NZ_CP018300|12|3|3103398-3104533|PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGACTTGATCGACGCGAACCTGTCTGACGCGAACCT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GGCTGGAAAAGGGCGCGGGGCAACCGCATCGTCAAGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GCGTTGTGGTCGTGTCGTGGAGCCTGTATTTCGCTG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CATTAGTTGGTGTTGTGATCGCTAAACGCCGGGGCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NZ_CP018300|12|8|3103398-3104681|CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGACTTGATCGACGCGAACCTGTCTGACGCGAACCT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GGCTGGAAAAGGGCGCGGGGCAACCGCATCGTCAAGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GCGTTGTGGTCGTGTCGTGGAGCCTGTATTTCGCTG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CATTAGTTGGTGTTGTGATCGCTAAACGCCGGGGCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTATCCGCGGGAAGAGATCACGAATCCGGCGTCGAAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ATGCTGAGCTGAGGCGCCGGATGATGGTGGTGCTGAAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NZ_CP018300|12|3|3103398-3104752|CRT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGACTTGATCGACGCGAACCTGTCTGACGCGAACCT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GGCTGGAAAAGGGCGCGGGGCAACCGCATCGTCAAGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GCGTTGTGGTCGTGTCGTGGAGCCTGTATTTCGCTG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CATTAGTTGGTGTTGTGATCGCTAAACGCCGGGGCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTATCCGCGGGAAGAGATCACGAATCCGGCGTCGAAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ATGCTGAGCTGAGGCGCCGGATGATGGTGGTGCTGAAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGACAGGGTGCGGTGGTCGCTGATCGGCTCCCCGA
GTTTCCGTCCCCTCTCGGTTTGAACCGCCCCGGTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003904058.1\|3109103_3110252_-\|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|187830
NZ_CP018300.1\|WP_003899489.1\|3099258_3099516_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_087902221.1\|3104778_3106040_-\|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP018300.1\|WP_003414296.1\|3113080_3113455_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844
NZ_CP018300.1\|WP_003414292.1\|3112360_3113071_-\|CRISPR-type-III-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP018300.1\|WP_003414190.1\|3099620_3099932_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414285.1\|3110347_3111475_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl\|CDD\|224251
NZ_CP018300.1\|WP_003899491.1\|3102436_3103249_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|225806
NZ_CP018300.1\|WP_003414198.1\|3101030_3102440_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018300.1\|WP_003917684.1\|3096677_3096932_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003911993.1\|3096226_3096502_+\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|226860
NZ_CP018300.1\|WP_003899488.1\|3097870_3099025_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018300.1\|WP_003414184.1\|3097480_3097672_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414195.1\|3100351_3100960_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414276.1\|3107732_3108074_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_CP018300.1\|WP_003414288.1\|3111471_3112380_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|224483
NZ_CP018300.1\|WP_009938577.1\|3097079_3097484_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414279.1\|3108074_3109091_-\|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	gnl\|CDD\|272998
NZ_CP018300.1\|WP_003900580.1\|3113451_3115890_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP018300.1\|WP_003899496.1\|3115886_3116831_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl\|CDD\|227838

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003904058.1\|3109103_3110252_-\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	0
NZ_CP018300.1\|WP_087902221.1\|3104778_3106040_-\|IS3-like-element-IS987-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NZ_CP018300.1\|WP_003414296.1\|3113080_3113455_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	4.56134e-21
NZ_CP018300.1\|WP_003414292.1\|3112360_3113071_-\|CRISPR-type-III-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.36536e-99
NZ_CP018300.1\|WP_003911993.1\|3096226_3096502_+\|DUF1778-domain-containing-protein	gnl\|CDD\|226860	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown].	1.95042e-26
NZ_CP018300.1\|WP_003899491.1\|3102436_3103249_+\|AAA-family-ATPase	gnl\|CDD\|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.94464e-110
NZ_CP018300.1\|WP_003414285.1\|3110347_3111475_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.40728e-139
NZ_CP018300.1\|WP_003414288.1\|3111471_3112380_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.37381e-109
NZ_CP018300.1\|WP_003414198.1\|3101030_3102440_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.41102e-28
NZ_CP018300.1\|WP_003899488.1\|3097870_3099025_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.94329e-16
NZ_CP018300.1\|WP_003414276.1\|3107732_3108074_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	3.66595e-25
NZ_CP018300.1\|WP_003414279.1\|3108074_3109091_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|272998	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1. This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.	2.72742e-113
NZ_CP018300.1\|WP_003900580.1\|3113451_3115890_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NZ_CP018300.1\|WP_003899496.1\|3115886_3116831_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.02032e-78

>NZ_CP018300.1|WP_003899491.1|3102436_3103249_+|AAA-family-ATPase
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NZ_CP018300.1|WP_003414198.1|3101030_3102440_+|DDE-type-integrase/transposase/recombinase
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NZ_CP018300.1|WP_003414195.1|3100351_3100960_+|hypothetical-protein
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NZ_CP018300.1|WP_003414190.1|3099620_3099932_+|hypothetical-protein
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NZ_CP018300.1|WP_003899489.1|3099258_3099516_+|hypothetical-protein
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NZ_CP018300.1|WP_003899488.1|3097870_3099025_+|DDE-type-integrase/transposase/recombinase
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NZ_CP018300.1|WP_003414184.1|3097480_3097672_+|hypothetical-protein
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NZ_CP018300.1|WP_009938577.1|3097079_3097484_+|hypothetical-protein
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NZ_CP018300.1|WP_003917684.1|3096677_3096932_-|hypothetical-protein
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NZ_CP018300.1|WP_003911993.1|3096226_3096502_+|DUF1778-domain-containing-protein
MPETLTGRLNFRLSPEQEQALRHAAALTGQSLSGFVLSAAVDHAHDLLARANRIELSEAAFRRFVAALDEPDEAAPELVRLARRKSRIPPH
>NZ_CP018300.1|WP_087902221.1|3104778_3106040_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NZ_CP018300.1|WP_003414276.1|3107732_3108074_-|CRISPR-associated-endonuclease-Cas2
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
>NZ_CP018300.1|WP_003414279.1|3108074_3109091_-|CRISPR-associated-endonuclease-Cas1
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
>NZ_CP018300.1|WP_003904058.1|3109103_3110252_-|type-III-A-CRISPR-associated-protein-Csm6
MLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG
>NZ_CP018300.1|WP_003414285.1|3110347_3111475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNTYLKPFELTLRCLGPVFIGSGEKRTSKEYHVEGDRVYFPDMELLYADIPAHKRKSFEAFVMNTDGAQATAPLKEWVEPNAVKLDPAKHRGYEVKIGSIEPRRASRGRGGRMTRKKLTLNEIHAFIKDPLGRPYVPGSTVKGMLRSIYLQSLVHKRTAQPVRVPGHQTREHRQYGERFERKELRKSGRPNTRPQDAVNDLFQAIRVTDSPALRTSDLLICQKMDMNVHGKPDGLPLFRECLAPGTSISHRVVVDTSPTARGGWREGERFLETLAETAASVNQARYAEYRAMYPGVNAIVGPIVYLGGGAGYRSKTFVTDQDDMAKVLDAQFGKVVKHVDKTRELRVSPLVLKRTKIDNICYEMGQCELSIRRAE
>NZ_CP018300.1|WP_003414288.1|3111471_3112380_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA
>NZ_CP018300.1|WP_003414292.1|3112360_3113071_-|CRISPR-type-III-associated-RAMP-protein-Csm3
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
>NZ_CP018300.1|WP_003414296.1|3113080_3113455_-|type-III-A-CRISPR-associated-protein-Csm2
MSVIQDDYVKQAEVIRGLPKKKNGFELTTTQLRVLLSLTAQLFDEAQQSANPTLPRQLKEKVQYLRVRFVYQSGREDAVKTFVRNAKLLEALEGIGDSRDGLLRFCRYMEALAAYKKYLDPKDK
>NZ_CP018300.1|WP_003900580.1|3113451_3115890_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNPQLIEAIIGCLLHDIGKPVQRAALGYPGRHSAIGRAFMKKVWLRDSRNPSQFTDEVDEADIGVSDRRILDAISYHHSSALRTAAENGRLAADAPAYIAYIADNIAAGTDRRKADSDDGHGASTWDPDTPLYSMFNRFGSGTANLAFAPEMLDDRKPINIPSPRRIEFDKDRYAAIVNKLKAILVDLERSDTYLASLLNVLEATLSFVPSSTDASEVVDVSLFDHLKLTGALGACIWHYLQATGQSDFKSALFDKQDTFYNEKAFLLTTFDVSGIQDFIYTIHSSGAAKMLRARSFYLEMLTEHLIDELLARVGLSRANLNYSGGGHAYLLLPNTESARKSVEQFEREANDWLLENFATRLFIATGSVPLAANDLMRRPNESASQASNRALRYSGLYRELSEQLSAKKLARYSADQLRELNSRDHDGQKGDRECSVCHTVNRTVSADDEPKCSLCQALTAASSQIQSESRRFLLISDGATKGLPLPFGATLTFCSRADADKALQQPQTRRRYAKNKFFAGECLGTGLWVGDYVAQMEFGDYVKRASGIARLGVLRLDVDNLGQAFTHGFMEQGNGKFNTISRTAAFSRMLSLFFRQHINYVLARPKLRPITGDDPARPREATIIYSGGDDVFVVGAWDDVIEFGIELRERFHEFTQGKLTVSAGIGMFPDKYPISVMAREVGDLEDAAKSLPGKNGVALFDREFTFGWDELLSKVIEEKYRHIADYFSGNEERGMAFIYKLLELLAERDDRITKARWVYFLTRMRNPTGDTAPFQQFANRLHQWFQDPTDAKQLKTALHLYIYRTRKEESE
>NZ_CP018300.1|WP_003899496.1|3115886_3116831_-|CRISPR-associated-endoribonuclease-Cas6
MAARRGGIRRTDLLRRSGQPRGRHRASAAESGLTWISPTLILVGFSHRGDRRMTEHLSRLTLTLEVDAPLERARVATLGPHLHGVLMESIPADYVQTLHTVPVNPYSQYALARSTTSLEWKISTLTNEARQQIVGPINDAAFAGFRLRASGIATQVTSRSLEQNPLSQFARIFYARPETRKFRVEFLTPTAFKQSGEYVFWPDPRLVFQSLAQKYGAIVDGEEPDPGLIAEFGQSVRLSAFRVASAPFAVGAARVPGFTGSATFTVRGVDTFASYIAALLWFGEFSGCGIKASMGMGAIRVQPLAPREKCVPKP

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Crispr_ID: NZ_CP018300_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_13

3106117-3107684

TypeIII

II-B,III-A

Consensus_repeat	Method
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRT

21 spacers

cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6

The CRISPR arrays of NZ_CP018300_13

>merge|NZ_CP018300|13|3106117-3107684|PILER-CR,CRISPRCasFinder,CRT
GTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGACGTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGGCGATTTACGACGCTGACGGGAACTCGTGCGAATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCGCGAAATTCACTGCGCGTTATTCAAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGAGCCGACCATCCGCATCACACCGAAAGGGTTGGCGCAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACATGCGAATCCGCTGTCAGCACATGGGATTCCGAGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTAGAAGGCGATCACTGGAAGCACGGCGCTTGCGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NZ_CP018300|13|4|3106117-3107684|PILER-CR
GTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGAC	GTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGGCGATTTACGACGCTGACGGGAACTCGTGCGAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCG	CGAAATTCACTGCGCGTTATTCAAGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGA	GCCGACCATCCGCATCACACCGAAAGGGTTGGCGCAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGT	GGGGAGAGGGAATGGCAATGATGGTCGACGAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCG	GACAGCATCTCCCCGGGCGGGCAGCAGATATCCCATGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGAC	CCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGG	AAGTCAACTAGAGCGGGTGTCGAACGCTGCCCGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACATGC	GAATCCGCTGTCAGCACATGGGATTCCGAGTGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAG	GCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGCGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCAGC	GCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGC	TGAAATTGAAGCCGGAAATGACGACGCATTGGTGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAA	GCCCGCTAATCCCGCACAAGTGGTCAGAAAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGA	TGATTGGTCGGCGTATGACGTGCTACTGAGGTGTTGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTAGA	AGGCGATCACTGGAAGCACGGCGCTTGCGAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGG	TCAAAAGCTGTCGCCCAAGCATGAGGCAAAAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGA	CTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGTGC	AAGAATTCCGGGTTGCAGTGCAACACGGTTTTAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NZ_CP018300|13|9|3106117-3107684|CRISPRCasFinder
GTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGAC	GTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGGCGATTTACGACGCTGACGGGAACTCGTGCGAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCG	CGAAATTCACTGCGCGTTATTCAAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGAGCCGACCATCCGCATCACACCGAAAGGGTTGGCGCAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ATGCGAATCCGCTGTCAGCACATGGGATTCCGAGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TAGAAGGCGATCACTGGAAGCACGGCGCTTGCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NZ_CP018300|13|4|3106117-3107684|CRT
GTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGAC	GTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGGCGATTTACGACGCTGACGGGAACTCGTGCGAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCG	CGAAATTCACTGCGCGTTATTCAAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGAGCCGACCATCCGCATCACACCGAAAGGGTTGGCGCAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ATGCGAATCCGCTGTCAGCACATGGGATTCCGAGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TAGAAGGCGATCACTGGAAGCACGGCGCTTGCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003904058.1\|3109103_3110252_-\|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|187830
NZ_CP018300.1\|WP_003899489.1\|3099258_3099516_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_087902221.1\|3104778_3106040_-\|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP018300.1\|WP_003899491.1\|3102436_3103249_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|225806
NZ_CP018300.1\|WP_003414292.1\|3112360_3113071_-\|CRISPR-type-III-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP018300.1\|WP_003414190.1\|3099620_3099932_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003913758.1\|3117008_3117554_-\|DUF1802-family-protein	unknown	unknown	gnl\|CDD\|226743
NZ_CP018300.1\|WP_009938577.1\|3097079_3097484_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414198.1\|3101030_3102440_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018300.1\|WP_003414276.1\|3107732_3108074_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_CP018300.1\|WP_003414285.1\|3110347_3111475_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl\|CDD\|224251
NZ_CP018300.1\|WP_003899488.1\|3097870_3099025_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018300.1\|WP_003414184.1\|3097480_3097672_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414195.1\|3100351_3100960_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414288.1\|3111471_3112380_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|224483
NZ_CP018300.1\|WP_003917684.1\|3096677_3096932_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003414279.1\|3108074_3109091_-\|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	gnl\|CDD\|272998
NZ_CP018300.1\|WP_003900580.1\|3113451_3115890_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP018300.1\|WP_003414296.1\|3113080_3113455_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844
NZ_CP018300.1\|WP_003899496.1\|3115886_3116831_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl\|CDD\|227838

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003904058.1\|3109103_3110252_-\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	0
NZ_CP018300.1\|WP_087902221.1\|3104778_3106040_-\|IS3-like-element-IS987-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NZ_CP018300.1\|WP_003899491.1\|3102436_3103249_+\|AAA-family-ATPase	gnl\|CDD\|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.94464e-110
NZ_CP018300.1\|WP_003414292.1\|3112360_3113071_-\|CRISPR-type-III-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.36536e-99
NZ_CP018300.1\|WP_003913758.1\|3117008_3117554_-\|DUF1802-family-protein	gnl\|CDD\|226743	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown].	1.13775e-85
NZ_CP018300.1\|WP_003414296.1\|3113080_3113455_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	4.56134e-21
NZ_CP018300.1\|WP_003414198.1\|3101030_3102440_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.41102e-28
NZ_CP018300.1\|WP_003414276.1\|3107732_3108074_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	3.66595e-25
NZ_CP018300.1\|WP_003414285.1\|3110347_3111475_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.40728e-139
NZ_CP018300.1\|WP_003899488.1\|3097870_3099025_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.94329e-16
NZ_CP018300.1\|WP_003414288.1\|3111471_3112380_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.37381e-109
NZ_CP018300.1\|WP_003414279.1\|3108074_3109091_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|272998	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1. This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.	2.72742e-113
NZ_CP018300.1\|WP_003900580.1\|3113451_3115890_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NZ_CP018300.1\|WP_003899496.1\|3115886_3116831_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.02032e-78

>NZ_CP018300.1|WP_087902221.1|3104778_3106040_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NZ_CP018300.1|WP_003899491.1|3102436_3103249_+|AAA-family-ATPase
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NZ_CP018300.1|WP_003414198.1|3101030_3102440_+|DDE-type-integrase/transposase/recombinase
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NZ_CP018300.1|WP_003414195.1|3100351_3100960_+|hypothetical-protein
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NZ_CP018300.1|WP_003414190.1|3099620_3099932_+|hypothetical-protein
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NZ_CP018300.1|WP_003899489.1|3099258_3099516_+|hypothetical-protein
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NZ_CP018300.1|WP_003899488.1|3097870_3099025_+|DDE-type-integrase/transposase/recombinase
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NZ_CP018300.1|WP_003414184.1|3097480_3097672_+|hypothetical-protein
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NZ_CP018300.1|WP_009938577.1|3097079_3097484_+|hypothetical-protein
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NZ_CP018300.1|WP_003917684.1|3096677_3096932_-|hypothetical-protein
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NZ_CP018300.1|WP_003414276.1|3107732_3108074_-|CRISPR-associated-endonuclease-Cas2
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
>NZ_CP018300.1|WP_003414279.1|3108074_3109091_-|CRISPR-associated-endonuclease-Cas1
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
>NZ_CP018300.1|WP_003904058.1|3109103_3110252_-|type-III-A-CRISPR-associated-protein-Csm6
MLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG
>NZ_CP018300.1|WP_003414285.1|3110347_3111475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNTYLKPFELTLRCLGPVFIGSGEKRTSKEYHVEGDRVYFPDMELLYADIPAHKRKSFEAFVMNTDGAQATAPLKEWVEPNAVKLDPAKHRGYEVKIGSIEPRRASRGRGGRMTRKKLTLNEIHAFIKDPLGRPYVPGSTVKGMLRSIYLQSLVHKRTAQPVRVPGHQTREHRQYGERFERKELRKSGRPNTRPQDAVNDLFQAIRVTDSPALRTSDLLICQKMDMNVHGKPDGLPLFRECLAPGTSISHRVVVDTSPTARGGWREGERFLETLAETAASVNQARYAEYRAMYPGVNAIVGPIVYLGGGAGYRSKTFVTDQDDMAKVLDAQFGKVVKHVDKTRELRVSPLVLKRTKIDNICYEMGQCELSIRRAE
>NZ_CP018300.1|WP_003414288.1|3111471_3112380_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA
>NZ_CP018300.1|WP_003414292.1|3112360_3113071_-|CRISPR-type-III-associated-RAMP-protein-Csm3
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
>NZ_CP018300.1|WP_003414296.1|3113080_3113455_-|type-III-A-CRISPR-associated-protein-Csm2
MSVIQDDYVKQAEVIRGLPKKKNGFELTTTQLRVLLSLTAQLFDEAQQSANPTLPRQLKEKVQYLRVRFVYQSGREDAVKTFVRNAKLLEALEGIGDSRDGLLRFCRYMEALAAYKKYLDPKDK
>NZ_CP018300.1|WP_003900580.1|3113451_3115890_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNPQLIEAIIGCLLHDIGKPVQRAALGYPGRHSAIGRAFMKKVWLRDSRNPSQFTDEVDEADIGVSDRRILDAISYHHSSALRTAAENGRLAADAPAYIAYIADNIAAGTDRRKADSDDGHGASTWDPDTPLYSMFNRFGSGTANLAFAPEMLDDRKPINIPSPRRIEFDKDRYAAIVNKLKAILVDLERSDTYLASLLNVLEATLSFVPSSTDASEVVDVSLFDHLKLTGALGACIWHYLQATGQSDFKSALFDKQDTFYNEKAFLLTTFDVSGIQDFIYTIHSSGAAKMLRARSFYLEMLTEHLIDELLARVGLSRANLNYSGGGHAYLLLPNTESARKSVEQFEREANDWLLENFATRLFIATGSVPLAANDLMRRPNESASQASNRALRYSGLYRELSEQLSAKKLARYSADQLRELNSRDHDGQKGDRECSVCHTVNRTVSADDEPKCSLCQALTAASSQIQSESRRFLLISDGATKGLPLPFGATLTFCSRADADKALQQPQTRRRYAKNKFFAGECLGTGLWVGDYVAQMEFGDYVKRASGIARLGVLRLDVDNLGQAFTHGFMEQGNGKFNTISRTAAFSRMLSLFFRQHINYVLARPKLRPITGDDPARPREATIIYSGGDDVFVVGAWDDVIEFGIELRERFHEFTQGKLTVSAGIGMFPDKYPISVMAREVGDLEDAAKSLPGKNGVALFDREFTFGWDELLSKVIEEKYRHIADYFSGNEERGMAFIYKLLELLAERDDRITKARWVYFLTRMRNPTGDTAPFQQFANRLHQWFQDPTDAKQLKTALHLYIYRTRKEESE
>NZ_CP018300.1|WP_003899496.1|3115886_3116831_-|CRISPR-associated-endoribonuclease-Cas6
MAARRGGIRRTDLLRRSGQPRGRHRASAAESGLTWISPTLILVGFSHRGDRRMTEHLSRLTLTLEVDAPLERARVATLGPHLHGVLMESIPADYVQTLHTVPVNPYSQYALARSTTSLEWKISTLTNEARQQIVGPINDAAFAGFRLRASGIATQVTSRSLEQNPLSQFARIFYARPETRKFRVEFLTPTAFKQSGEYVFWPDPRLVFQSLAQKYGAIVDGEEPDPGLIAEFGQSVRLSAFRVASAPFAVGAARVPGFTGSATFTVRGVDTFASYIAALLWFGEFSGCGIKASMGMGAIRVQPLAPREKCVPKP
>NZ_CP018300.1|WP_003913758.1|3117008_3117554_-|DUF1802-family-protein
MTPALKEWSAAVHALLDGRQTVLLRKGGIGEKRFEVAAHEFLLFPTVAHSHAERVRPEHRDLLGPAAADSTDECVLLRAAAKVVAALPVNRPEGLDAIEDLHIWTAESVRADRLDFRPKHKLAVLVVSAIPLAEPVRLARRPEYGGCTSWVQLPVTPTLAAPVHDEAALAEVAARVREAVG

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Crispr_ID: NZ_CP018300_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_14

3724836-3725683

Orphan

Consensus_repeat	Method
CCGCCGNNNCCNCCGTNNCCGCC	CRT

11 spacers

The CRISPR arrays of NZ_CP018300_14

>merge|NZ_CP018300|14|3724836-3725683|CRT
CCGCCGTTGCCGCCGGCACCGCCGTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCCTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCGCCCCCGTTGCCGCCCTTGCCGCCGTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCGTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGGCCGCCGTTACCACCGGCGCCGCCGTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCACCTCCGTTGCCACCGTTGCCGCCGCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACACCGCCGGCCCCACCCTTGCCGCCAACGCCCACTTCACCGCCGTTGCCGCCGTCACCGCCGGCACCCTGGTTGACGGCCAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCACCGCCGGCGCCGCCGTCCCCGGCCTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGTGCCGCCACCACCGCCGTCACCGCCCTTGCCGCCGTTGCCGCCCATACCGCCATCGGCACCGGGCGAACCCAAGGTGGCGGCGTCGAATCCGTTTCCGCCGGCGCCGCCGCTACCGCCGGCACCGCCCTTGCCGCCGACGCCGCCGTCGCCGTGCTGGGCGCCGCCATTTCCGCCATTACCGCCGTGGCCCCC

>NZ_CP018300|14|5|3724836-3725683|CRT
CCGCCGTTGCCGCCGGCACCGCC	GTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	CTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCG
CCCCCGTTGCCGCCCTTGCCGCC	GTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	GTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGG
CCGCCGTTACCACCGGCGCCGCC	GTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCA
CCTCCGTTGCCACCGTTGCCGCC	GCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACA
CCGCCGGCCCCACCCTTGCCGCC	AACGCCCACTTCACCGCCGTTGCCGCCGTCA
CCGCCGGCACCCTGGTTGACGGC	CAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCA
CCGCCGGCGCCGCCGTCCCCGGC	CTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGTG
CCGCCACCACCGCCGTCACCGCC	CTTGCCGCCGTTGCCGCCCATACCGCCATCGGCACCGGGCGAACCCAAGGTGGCGGCGTCGAATCCGTTT
CCGCCGGCGCCGCCGCTACCGCC	GGCACCGCCCTTGCCGCCGACGCCGCCGTCGCCGTGCTGGGCGCCGCCATTT
CCGCCATTACCGCCGTGGCCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_009939158.1\|3740180_3751331_-\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NZ_CP018300.1\|WP_070890838.1\|3727939_3737413_-\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NZ_CP018300.1\|WP_009940431.1\|3708192_3708825_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|184875
NZ_CP018300.1\|WP_071854233.1\|3752719_3753130_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|366708
NZ_CP018300.1\|WP_003417440.1\|3706897_3707908_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|234866
NZ_CP018300.1\|WP_003417461.1\|3712900_3713632_+\|methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP018300.1\|WP_003914152.1\|3738521_3739340_-\|transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP018300.1\|WP_003417458.1\|3711764_3712904_+\|homoserine-O-acetyltransferase	unknown	unknown	gnl\|CDD\|234678
NZ_CP018300.1\|WP_003417421.1\|3704213_3705059_-\|DUF732-domain-containing-protein	unknown	unknown	gnl\|CDD\|368380
NZ_CP018300.1\|WP_003417619.1\|3727426_3727684_-\|DUF3017-domain-containing-protein	unknown	unknown	gnl\|CDD\|378602
NZ_CP018300.1\|WP_025983990.1\|3713640_3721254_-\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NZ_CP018300.1\|WP_003900026.1\|3705533_3705974_+\|heavy-metal-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NZ_CP018300.1\|WP_003417739.1\|3752450_3752822_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP018300.1\|WP_003900028.1\|3710403_3711753_+\|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	unknown	unknown	gnl\|CDD\|236105
NZ_CP018300.1\|WP_049961743.1\|3738038_3738485_+\|transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP018300.1\|WP_003417452.1\|3708891_3710121_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|236226
NZ_CP018300.1\|WP_003417741.1\|3752964_3753225_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_009938650.1\|3739556_3739844_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003417738.1\|3751574_3752369_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369658
NZ_CP018300.1\|WP_003417435.1\|3706007_3706877_-\|inner-membrane-protein-YhjD	unknown	unknown	gnl\|CDD\|188082

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_009939158.1\|3740180_3751331_-\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	8.31505e-80
NZ_CP018300.1\|WP_070890838.1\|3727939_3737413_-\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	9.79647e-79
NZ_CP018300.1\|WP_009940431.1\|3708192_3708825_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	1.23792e-15
NZ_CP018300.1\|WP_071854233.1\|3752719_3753130_-\|FAD-binding-protein	gnl\|CDD\|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	4.01471e-07
NZ_CP018300.1\|WP_003417440.1\|3706897_3707908_-\|tryptophan--tRNA-ligase	gnl\|CDD\|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	0
NZ_CP018300.1\|WP_003417461.1\|3712900_3713632_+\|methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.03104e-26
NZ_CP018300.1\|WP_003914152.1\|3738521_3739340_-\|transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.05794e-20
NZ_CP018300.1\|WP_003417458.1\|3711764_3712904_+\|homoserine-O-acetyltransferase	gnl\|CDD\|234678	PRK00175, metX, homoserine O-acetyltransferase; Provisional.	0
NZ_CP018300.1\|WP_003417421.1\|3704213_3705059_-\|DUF732-domain-containing-protein	gnl\|CDD\|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	8.32313e-18
NZ_CP018300.1\|WP_003417619.1\|3727426_3727684_-\|DUF3017-domain-containing-protein	gnl\|CDD\|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	3.92596e-11
NZ_CP018300.1\|WP_025983990.1\|3713640_3721254_-\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.06966e-84
NZ_CP018300.1\|WP_003900026.1\|3705533_3705974_+\|heavy-metal-responsive-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.31191e-56
NZ_CP018300.1\|WP_003417739.1\|3752450_3752822_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	7.3689e-14
NZ_CP018300.1\|WP_003900028.1\|3710403_3711753_+\|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	gnl\|CDD\|236105	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated.	0
NZ_CP018300.1\|WP_049961743.1\|3738038_3738485_+\|transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.45693e-11
NZ_CP018300.1\|WP_003417452.1\|3708891_3710121_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|236226	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase.	0
NZ_CP018300.1\|WP_003417738.1\|3751574_3752369_-\|hypothetical-protein	gnl\|CDD\|369658	pfam08031, BBE, Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine.	2.38492e-05
NZ_CP018300.1\|WP_003417435.1\|3706007_3706877_-\|inner-membrane-protein-YhjD	gnl\|CDD\|188082	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD. This family, including YhjD in E. coli, is a conserved inner membrane protein homologous YihY, which in turn was incorrectly assigned to be ribonuclease BN. This, any suggestion this family is similar to ribonucleases should be removed. [Transcription, Degradation of RNA].	3.67774e-123

>NZ_CP018300.1|WP_025983990.1|3713640_3721254_-|PPE-family-protein
MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGPSSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSLALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAEPAKSLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGEANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGVLWRGDYQGLLGFSSGANVLPVIPLSLDINGGVGAITIEPIHILPDIPININETLYLGPLVVPPINVPAISLGVGIPNISIGPIKINPITLWPAQNFNQTITLAWPVSSITIPQIQQVALSPSPIPTTLIGPIHINTGFSIPVTFSYSTPALTLFPVGLSIPTGGPLTLTLGVTAGTEAFTIPGFSIPEQPLPLAINVIGHINALSTPAITIDNIPLNLHAIGGVGPVDIVGGNVPASPGFGNSTTAPSSGFFNTGAGGVSGFGNVGAHTSGWFNQSTQAMQVLPGTVSGYFNSGTLMSGIGNVGTQLSGMLSGGALGGNNFGLGNIGFDNVGFGNAGSSNFGLANMGIGNIGLANTGNGNIGIGLSGDNLTGFGGFNSGSENVGLFNSGTGNVGFFNSGTGNLGVFNSGSHNTGFFLTGNNINVLAPFTPGTLFTISEIPIDLQVIGGIGPIHVQPIDIPAFDIQITGGFIGIREFTLPEITIPAIPIHVTGTVGLEGFHVNPAFVLFGQTAMAEITADPVVLPDPFITIDHYGPPLGPPGAKFPSGSFYLSISDLQINGPIIGSYGGPGTIPGPFGATFNLSTSSLALFPAGLTVPDQTPVTVNLTGGLDSITLFPGGLAFPENPVVSLTNFSVGTGGFTVFPQGFTVDRIPVDLHTTLSIGPFPFRWDYIPPTPANGPIPAVPGGFGLTSGLFPFHFTLNGGIGPISIPTTTVVDALNPLLTVTGNLEVGPFTVPDIPIPAINFGLDGNVNVSFNAPATTLLSGLGITGSIDISGIQITNIQTQPAQLFMSVGQTLFLFDFRDGIELNPIVIPGSSIPITMAGLSIPLPTVSESIPLNFSFGSPASTVKSMILHEILPIDVSINLEDAVFIPATVLPAIPLNVDVTIPVGPINIPIITEPGSGNSTTTTSDPFSGLAVPGLGVGLLGLFDGSIANNLISGFNSAVGIVGPNVGLSNLGGGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNIGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWTGDYQGLLDFSFPVGPLIPQTHLVHLRETVNLGPIHIDPIHVHIPPLLDIDQTIDLGSFTVAPITVAPIALDYHETFDLGPLVIFPPMNIPATVIESFSTAPGGPAPPPFVIPATSNVFISTVDFATGNNVIGPFSGALAPTTIQLGASGPSFSVLNLSIPPIHIPGLTIPSVPLRIDVDGGIPGFTLFPDGLTFPKIPVHVDAFAGIPDFTIFPNGYTIDPIPLQLNLDLTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVANIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPVFDLGPITVQDITIPALGLDPATGVTVGPIFSSGSIIDPFSLTLLGFINVNVPAIQTAPSEILPFTVLLSSLGVTHLTPEITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRIPVVLDVNALLGPINAGLVIPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGFGNVGQQLAGLIYTGTGP
>NZ_CP018300.1|WP_003417461.1|3712900_3713632_+|methyltransferase
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA
>NZ_CP018300.1|WP_003417458.1|3711764_3712904_+|homoserine-O-acetyltransferase
MTISDVPTQTLPAEGEIGLIDVGSLQLESGAVIDDVCIAVQRWGKLSPARDNVVVVLHALTGDSHITGPAGPGHPTPGWWDGVAGPGAPIDTTRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVQADVAALAALGITEVAAVVGGSMGGARALEWVVGYPDRVRAGLLLAVGARATADQIGTQTTQIAAIKADPDWQSGDYHETGRAPDAGLRLARRFAHLTYRGEIELDTRFANHNQGNEDPTAGGRYAVQSYLEHQGDKLLSRFDAGSYVILTEALNSHDVGRGRGGVSAALRACPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLRVVESVYGHDGFLVETEAVGELIRQTLGLADREGACRR
>NZ_CP018300.1|WP_003900028.1|3710403_3711753_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase
MSADSNSTDADPTAHWSFETKQIHAGQHPDPTTNARALPIYATTSYTFDDTAHAAALFGLEIPGNIYTRIGNPTTDVVEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLGIEVSFVDDPDDLDTWQAAVRPNTKAFFAETISNPQIDLLDTPAVSEVAHRNGVPLIVDNTIATPYLIQPLAQGADIVVHSATKYLGGHGAAIAGVIVDGGNFDWTQGRFPGFTTPDPSYHGVVFAELGPPAFALKARVQLLRDYGSAASPFNAFLVAQGLETLSLRIERHVANAQRVAEFLAARDDVLSVNYAGLPSSPWHERAKRLAPKGTGAVLSFELAGGIEAGKAFVNALKLHSHVANIGDVRSLVIHPASTTHAQLSPAEQLATGVSPGLVRLAVGIEGIDDILADLELGFAAARRFSADPQSVAAF
>NZ_CP018300.1|WP_003417452.1|3708891_3710121_-|NADP-dependent-isocitrate-dehydrogenase
MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN
>NZ_CP018300.1|WP_009940431.1|3708192_3708825_+|alpha/beta-fold-hydrolase
MLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVTGIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLATLPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVPSHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRITELITSFIEECCPHVRAS
>NZ_CP018300.1|WP_003417440.1|3706897_3707908_-|tryptophan--tRNA-ligase
MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADVLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL
>NZ_CP018300.1|WP_003417435.1|3706007_3706877_-|inner-membrane-protein-YhjD
MGELAEPGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLTYYTIFAIFPLLMVGFGVGGFALSRRPELLTTLEERIRTSVSGAVGQQLVDLMNSAIDARASVGVIGLATAAWVGLGWMWHLREALSQMWAHPVAPAGYLRTKLSDLAAMVGTFVVIVATIALTVLGHARPMAAVLRWLEIPQFSVFDEIFRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGFELFKQVGAIYLQIVLRSPAGAVFGPVLGLMVFAFVTAWLILFATAWAATASA
>NZ_CP018300.1|WP_003900026.1|3705533_3705974_+|heavy-metal-responsive-transcriptional-regulator
MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA
>NZ_CP018300.1|WP_003417421.1|3704213_3705059_-|DUF732-domain-containing-protein
MFTGIASHAGALGAALVVLIGAAILHDGPAAADPNQDDRFLALLEKKEIPAVANVPRVIDAAHKVCRKLDGGMPVNDIVDGLRNDAYNIDPVMRLYPVRLTTTMTRFISAAVEIYCPNHHSKMAFAMANFEPGSNEPTHRVAASTRSAVNSGSDLRASVSDMTIMSPGWREPTGAMLASVLGAVRAGDPLIPNPPPIPVPPPAAQTLIPPPPIVAPPPPRPAPPQQPPPPPPEVEPPAGVPQSGGAAGSGGAGSGGGGGGDGPVEPSPARPMPPGFIRLAP
>NZ_CP018300.1|WP_003417619.1|3727426_3727684_-|DUF3017-domain-containing-protein
MTVRAVLRRTVGAQWPILAGVNFWRRGALLIGIGVGVAAVLRLVLSEERAGLLVVRSKGIDFVTTVTVAAAMVYIASTIDPLGTG
>NZ_CP018300.1|WP_070890838.1|3727939_3737413_-|PPE-family-protein
MNFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNALFAGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGNFGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFANTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFGVFNSGSYNTGVGNAGTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNTGGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFISGNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGPLVVPDIVIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLNIDTRINQSFPVTVNWSTPAVTIFPNGISIPNNPLALLASASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGFSTPPITIDRIPLNLGASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQTEVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLSSAGTALNQSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVGLGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSGSFNTGIGNGGTGSTGLFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGNVDTGALMSGNFSNGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGLTGQANYGFAVPDIPIPAIHIDFDGAADAGFTAPATTLLSALGITGQFRFGPITVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPPIDIPASTINGISMSEVVPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINISIIDIPALPGFGNSTELPSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASGVLNSGVDISGMFNVSTLGSAPAVISGFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAGNLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLGALPGIGNIGLGNAGSNNVGFGNMGLGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTGIGNSGTGSTGLFNAGSFNTGLANAGSHNTGSLNAGNTNTGGFNPGNVNTGWFNAGHTNTGGFNTGNVNTGAFNSGSFNNGALWTGDHHGLVGFSYSIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVNIGPFRIEPIDVPAVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAPPPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGILIHTGPSSATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNIPQNAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALNISVPDSSVPIIIVPPTPGFGNATATPSSGFFNSGAGGVSGFGNFGAGSSGWWNQAHAALAGAGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGNVGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGDLNLGLGNIGNANVGFGNIGHGNVGFGNSGLGAALGIGNIGLGNAGSTNVGLANMGVGNIGFANTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNWGLFNSGSFNTGIGNSGTGSTGLFNAGGFTTGLANAGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGNVDTGALMSGNFSNGILWRGNYEGLFSYSYSLDVPRITILDAHFTGAFGPVVVPPIPVPAINAHLTGNAAMGAFTIPQIDIPALNPNVTGSVGFGPIAVPSVTIPALTAARAVLDMAASVGATSEIEPFIVWTSSGAIGPTWYSVGRIYNAGDLFVGGNIISGIPTLSTTGPVHAVFNAASQAFNTPALNIHQIPLGFQVPGSIDAITLFPGGLTFPANSLLNLDVFVGTPGATIPAITFPEIPANADGELYVIAGDIPLINIPPTPGIGNTTTVPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGAGSGIANVGTLHSGVLNLGSGLSGIYNTSTLPLGTPALVSGLGNVGDHLSGLLASNVGQNPITIVNIGLANVGNGNVGLGNIGNLNLGAANIGDVNLGFGNIGDVNLGFGNIGGGNVGFGNIGDANFGFGNSGLAAGLAGMGNIGLGNAGSGNVGWANMGLGNIGFGNTGTNNLGIGLTGDNQSGIGGLNSGTGNIGLFNSGTGNIGFFNSGTANFGLFNSGSYNTGIGNSGVASTGLVNAGGFNTGVANAGSYNTGSFNAGDTNTGGFNPGSTNTGWFNTGNANTGVANAGNVNTGALITGNFSNGILWRGNYEGLAGFSFGYPIPLFPAVGADVTGDIGPATIIPPIHIPSIPLGFAAIGHIGPISIPNIAIPSIHLGIDPTFDVGPITVDPITLTIPGLSLDAAVSEIRMTSGSSSGFKVRPSFSFFAVGPDGMPGGEVSILQPFTVAPINLNPTTLHFPGFTIPTGPIHIGLPLSLTIPGFTIPGGTLIPQLPLGLGLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGGAPGFGNDTTAPSSGFFNTGGGGGSGFSNSGSGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGTLGLVTSAFVSGFMNVGQQLSGLLFAGTGP
>NZ_CP018300.1|WP_049961743.1|3738038_3738485_+|transposase
MDAAITACHHIAIRDDVGARSIRFSVEPTLAGLRTLTDKLSGYDDIDATVEPTSMTWLPLTIAVENAGDTMHMAGARHCARLRGAIVGKSKSDVIDAEVLTRASEVFDLTPLTLPTPAQLALRRSVIRRAGAVIDANRSWRRLMSLAR
>NZ_CP018300.1|WP_003914152.1|3738521_3739340_-|transposase
MKAAAARRCWHGCKRAHRSSGRASSTVAIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKIDPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLTSHPRSTPSWSPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAGVSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
>NZ_CP018300.1|WP_009938650.1|3739556_3739844_-|hypothetical-protein
MSRRRRRARRAGVVSISVKEYAVTSPKDLPYGEDRIMVRWNKIRWRCREDYCKLGPFTEAITQVPARVRSTLRLRRQMAKAIGDAARSVGRGRPG
>NZ_CP018300.1|WP_009939158.1|3740180_3751331_-|PPE-family-protein
MEFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVALAVSNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLTALFASPAKALSLNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNVGFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVGLTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSGNYNTGVGNAGTASTGLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNTGAFISGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIPILPTIPLSIHQTVNLGPLVVPDIVIPAFGGGIGIPINIGPLTITPITLFAQQTFVNQLPFPTFSLGKITIPQIQTFDSNGQLVSFIGPIVIDTTIPGPTNPQIDLTIRWDTPPITLFPNGISAPDNPLGLLVSVSISNPGFTIPGFSVPAQPLPLSIDIEGQIDGFSTPPITIDRIPLTVGGGVTIGPITIQGLHIPAAPGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSSGWWNQAPSALLGAGSGVGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGVSAAGTTLRSMLAGNLGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGDGNLGLGNIGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGVGNIGFANTGTGNIGIGLVGDHRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIGNSGRFNTGIGNSGTASTGLFNAGSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWFNTGHANTGLANAGTFGTGAFMTGDYSNGLLWRGGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVPVPAVHVEITDATVGLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEPFRLSDPFITIDAFQVVAGVLFLENIIVPGLTVSGQILVTPTPIPLTLNLDTTPWTLFPNGFTIPAQTPVTVGMEVANDGFTFFPGGLTFPRASAGVTGLSVGLDAFTLLPDGFTLDTVPATFDGTILIGDIPIPIIDVPAVPGFGNTTTAPSSGFFNTGGGGGSGFANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVSGIGNLGQQLSGFLANGTVLNRSPIVNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLGNLGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVGNIGLANTGTGNIGIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSGSFNTGIGNSGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPGDINTGWFNTGIMNTGTRNTGALMSGTDSNGMLWRGDHEGLFGLSYGITIPQFPIRITTTGGIGPIVIPDTTILPPLHLQITGDADYSFTVPDIPIPAIHIGINGVVTVGFTAPEATLLSALKNNGSFISFGPITLSNIDIPPMDFTLGLPVLGPITGQLGPIHLEPIVVAGIGVPLEIEPIPLDAISLSESIPIRIPVDIPASVIDGISMSEVVPIDASVDIPAVTITGTTISAIPLGFDIRTSAGPLNIPIIDIPAAPGFGNSTQMPSSGFFNTGAGGGSGIGNLGAGVSGLLNQAGAGSLVGTLSGLGNAGTLASGVLNSGTAISGLFNVSTLDATTPAVISGFSNLGDHMSGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGEFNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNVGLGNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTGNIGFFNTGTGNFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGLANAGSYNTGSLNVGSFNTGGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSGSFNNGALWTGDYHGLVGFSFSIDIAGSTLLDLNETLNLGPIHIEQIDIPGMSLFDVHEIVEIGPFTIPQVDVPAIPLEIHESIHMDPIVLVPATTIPAQTRTIPLDIPASPGSTMTLPLISMRFEGEDWILGSTAAIPNFGDPFPAPTQGITIHTGPGPGTTGELKISIPGFEIPQIATTRFLLDVNISGGLPAFTLFAGGLTIPTNAIPLTIDASGALDPITIFPGGYTIDPLPLHLALNLTVPDSSIPIIDVPPTPGFGNTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALAGSGSGVLNVGTLGSGVLNVGSGVSGIYNTSVLPLGTPAVLSGLGNVGHQLSGVSAAGTALNQIPILNIGLADVGNFNVGFGNVGDVNLGAANLGAQNLGLGNVGTGNLGFANVGHGNIGFGNSGLTAGAAGLGNTGFGNAGSANYGFANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNFGIGNSGSFNTGIGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNAGDTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGLLWRGDHEGLFSLFYSLDVPRITIVDAHLDGGFGPVVLPPIPVPAVNAHLTGNVAMGAFTIPQIDIPALTPNITGSAAFRIVVGSVRIPPVSVIVEQIINASVGAEMRIDPFEMWTQGTNGLGITFYSFGSADGSPYATGPLVFGAGTSDGSHLTISASSGAFTTPQLETGPITLGFQVPGSVNAITLFPGGLTFPATSLLNLDVTAGAGGVDIPAITWPEIAASADGSVYVLASSIPLINIPPTPGIGNSTITPSSGFFNAGAGGGSGFGNFGAGTSGWWNQAHTALAGAGSGFANVGTLHSGVLNLGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLSGLLSGGSAVNPVTVLNIGLANVGSHNAGFGNVGEVNLGAANLGAHNLGFGNIGAGNLGFGNIGHGNVGVGNSGLTAGVPGLGNVGLGNAGGNNWGLANVGVGNIGLANTGTGNIGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNFGLFNSGSFNTGVGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDTNTGGFNPGSINTGWLNAGNANTGVANAGNVNTGAFVTGNFSNGILWRGDYQGLAGFAVGYTLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAVGGIGPIAIPDISVPSIHLGLDPAVHVGSITVNPITVRTPPVLVSYSQGAVTSTSGPTSEIWVKPSFFPGIRIAPSSGGGATSTQGAYFVGPISIPSGTVTFPGFTIPLDPIDIGLPVSLTIPGFTIPGGTLIPTLPLGLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINVPIAGFGGAPGFGNSTTLPSSGFFNTGAGGGSGFSNTGAGMSGLLNAMSDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGALGVVTAAVVSGFGNVGQQLSGLLFTGVGP
>NZ_CP018300.1|WP_003417738.1|3751574_3752369_-|hypothetical-protein
MLASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPPEGFVAGSDVIGTTNPAAAQAIVAAIGTWPPAAGRASALIDSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHHAVQHFSVGGYVNYLEANAAASQYFGANLSRLTTVRRKYDPDRIMYSGLDFSTRQVAERLLPALGFRVRFGVLVIRCALCTDTVKRLGTLPNLTWSRLKVNVAVTQEQAGVMDLPALPVRRTPRR
>NZ_CP018300.1|WP_003417739.1|3752450_3752822_-|FAD-binding-oxidoreductase
MSAATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCDALKSATVVLPGGDAVSASADDHAELFWALRGGGGGNFGVTTSMTFARFPTADCDVVRVDFAPSAAAQVLVG
>NZ_CP018300.1|WP_071854233.1|3752719_3753130_-|FAD-binding-protein
MGQSGLIDRRAGAAAGQRQGVHERKADLQFELQRLESGRGGDGRLAGRRPEGGFVAAASKLKIAVRGGGHSYIGASSANGAMVLDLLGLPGGVHFDSATRNVRCRPRPISMRSIKRWPVRAGRFRPAAARPWVWRV
>NZ_CP018300.1|WP_003417741.1|3752964_3753225_-|hypothetical-protein
MSRQTFLRGAVGAPATSAVFPTILARATPGDGWASLASSIGGQVLLPANGRAFTSGKQIFNSNYSGLNPAAVVTVASQADVRKAVS

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Crispr_ID: NZ_CP018300_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018300_15

4084902-4084990

Orphan

Consensus_repeat	Method
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018300_15

>merge|NZ_CP018300|15|4084902-4084990|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCCCGAGGAGGAGCCGAGCAATCGAACCGAGCTCGGCGACGATGCGGGCCGGATGACGGCC

>NZ_CP018300|15|10|4084902-4084990|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CGAGGAGGAGCCGAGCAATCGAACCGA
GCTCGGCGACGATGCGGGCCGGATGACGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018300.1\|WP_003899631.1\|4082015_4083971_+\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|234677
NZ_CP018300.1\|WP_003899635.1\|4090225_4090603_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003419728.1\|4090701_4091376_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_CP018300.1\|WP_003419718.1\|4087744_4088566_-\|CoA-pyrophosphatase	unknown	unknown	gnl\|CDD\|239518
NZ_CP018300.1\|WP_003419712.1\|4085569_4086553_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP018300.1\|WP_153301032.1\|4081849_4082005_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003419731.1\|4091481_4092276_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293836
NZ_CP018300.1\|WP_003419701.1\|4078754_4079681_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP018300.1\|WP_003419733.1\|4092282_4092738_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100006
NZ_CP018300.1\|WP_003900733.1\|4076255_4077902_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048
NZ_CP018300.1\|WP_003901693.1\|4081393_4081750_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003419721.1\|4088697_4089381_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP018300.1\|WP_003900734.1\|4086545_4087739_-\|acid-resistance-serine-protease-MarP	unknown	unknown	gnl\|CDD\|379142
NZ_CP018300.1\|WP_003419724.1\|4089380_4090118_-\|endonuclease-III	unknown	unknown	gnl\|CDD\|223255
NZ_CP018300.1\|WP_003899628.1\|4077898_4078762_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_CP018300.1\|WP_003899629.1\|4079682_4081308_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173853
NZ_CP018300.1\|WP_003419710.1\|4085050_4085569_+\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|377816
NZ_CP018300.1\|WP_003899626.1\|4075488_4076259_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018300.1\|WP_003419689.1\|4073870_4074734_+\|HAD-IB-family-hydrolase	unknown	unknown	gnl\|CDD\|273654
NZ_CP018300.1\|WP_003419708.1\|4084006_4084705_-\|protease	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP018300.1\|WP_003899631.1\|4082015_4083971_+\|acetate--CoA-ligase	gnl\|CDD\|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NZ_CP018300.1\|WP_003419728.1\|4090701_4091376_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.11707e-55
NZ_CP018300.1\|WP_003419718.1\|4087744_4088566_-\|CoA-pyrophosphatase	gnl\|CDD\|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	1.20605e-47
NZ_CP018300.1\|WP_003419712.1\|4085569_4086553_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.34553e-25
NZ_CP018300.1\|WP_003900734.1\|4086545_4087739_-\|acid-resistance-serine-protease-MarP	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.86888e-19
NZ_CP018300.1\|WP_003900733.1\|4076255_4077902_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NZ_CP018300.1\|WP_003419731.1\|4091481_4092276_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293836	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	3.29322e-75
NZ_CP018300.1\|WP_003419721.1\|4088697_4089381_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.72736e-22
NZ_CP018300.1\|WP_003419701.1\|4078754_4079681_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.57934e-99
NZ_CP018300.1\|WP_003419724.1\|4089380_4090118_-\|endonuclease-III	gnl\|CDD\|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	2.16645e-106
NZ_CP018300.1\|WP_003899628.1\|4077898_4078762_-\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.77559e-81
NZ_CP018300.1\|WP_003899629.1\|4079682_4081308_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.73988e-122
NZ_CP018300.1\|WP_003419710.1\|4085050_4085569_+\|phage-holin-family-protein	gnl\|CDD\|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	8.41555e-32
NZ_CP018300.1\|WP_003419733.1\|4092282_4092738_-\|RidA-family-protein	gnl\|CDD\|100006	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	7.62827e-68
NZ_CP018300.1\|WP_003419689.1\|4073870_4074734_+\|HAD-IB-family-hydrolase	gnl\|CDD\|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI\|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI\|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	5.37865e-86

>NZ_CP018300.1|WP_003419708.1|4084006_4084705_-|protease
MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGDTMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGNDGLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCGVTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCITKYIPLHTPAVVMSINADLADINAKNRPGAGFVPVPA
>NZ_CP018300.1|WP_003899631.1|4082015_4083971_+|acetate--CoA-ligase
MSESTPEVSSSYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWSGAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTDETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISPIARPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIRAAK
>NZ_CP018300.1|WP_153301032.1|4081849_4082005_+|hypothetical-protein
MPAARCKADQRVMCSLQDTGFLGYDCILVSDCTVTTLPSSTSAMPAVSSRG
>NZ_CP018300.1|WP_003901693.1|4081393_4081750_+|hypothetical-protein
MTVSYHATQSAGEPVGRCFGNAHTVVRDPVLATHRDCASQGKTSPDRALLACGILEEDRWCRRCGEEGSPRDTVTRRLTHWCGLHPGVSVDHSCLSRCCRLDCRRRGPAVPQRDPPRR
>NZ_CP018300.1|WP_003899629.1|4079682_4081308_-|ABC-transporter-substrate-binding-protein
MVRQMRAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSNGGRIIDRLFAGLMSYDAVGKPSLEVAQSIESADNVNYRITVKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPGDKSRTTMSGLRVVNDLEFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRIDLVPNPDYHGNRKPRNKGLRFEFYANLDTAYADLLSGNLDVLDTIPPSALTVYQRDLGDHATSGPAAINQTLDTPLRLPHFGGEEGRLRRLALSAAINRPQICQQIFAGTRSPARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAGWRGDYPSMIEFLAPLFTAGAGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRILFHDMPVVPLWDYISVVGWSSQVSNVTVTWNGLPDYENIVKA
>NZ_CP018300.1|WP_003419701.1|4078754_4079681_-|ABC-transporter-permease
MGWYVARRVAVMVPVFLGATLLIYGMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLGGILHGDLGRAYSGLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLRQGGIFDSAVLVTGLVIIAIPIFVLGFLAQFLFGVQLEIAPVTVGERASVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADYVRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFNIHGVGGVLYQAVTRQETPTVVSIVTVLVLIYLITNLLVDLLYAALDPRIRYG
>NZ_CP018300.1|WP_003899628.1|4077898_4078762_-|ABC-transporter-permease
MAEHTGFWLDAWRGLRRRPKFVIAAALILLILVVAAFPSLFTAADPTYADPSQSMLAPSAAHWFGTDLQGHDIYSRTVYGARASVTVGLGATLAVFVVGGALGALAGFYGSWIDAVVSRVTDVFLGLPLLLAAIVLMQVMHHRTVWTVIAILALFGWPQVARIARGAVLEVRASDYVLAAKALGLNRFQILLRHALPNAVGPVIAVATVALGIFIVTEATLSYLGVGLPTSVVSWGGDINVAQTRLRSGSPILFYPAGALAITVLAFMMMGDALRDALDPASRAWRA
>NZ_CP018300.1|WP_003900733.1|4076255_4077902_-|ABC-transporter-ATP-binding-protein
MSVPAAPLLSVEGLEVTFGTDAPAVCGVDLAVRSGQTVAVVGESGSGKSTTAAAILGLLPAGGRITAGRVVFDGRDITGADAKRLRSIRGREIGYVPQDPMTNLNPVWKVGFQVTEALRANTDGRAARRRAVELLAEAGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVTVQRQVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQSILQSPQHEYTRRLVAAAPSLTARSRRPPESRSRATTQAGDILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAIVGESGSGKSTLARMVLGLLQPTSGTVVFDGTYDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHHVGDRRQRQRAVRELVDQVALPSSILGRRPRELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADLGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQLLQAIPGAPSAPRKVGNL
>NZ_CP018300.1|WP_003899626.1|4075488_4076259_-|hypothetical-protein
MTVDPLAPLMELPGVAAASDRVRDALSRVHRHRANLRGWPVAAAEASLRAARASSVLDGGPARLHDAGAPTSGKPALSDPVFAGALRVGQALEGGAGPVVGVWRRAPLQALARLHMLAAADQVDDDRLGRPRSDADVGPRLELLADVVTHPTLASAPVVAAVAHGELLTLRPFGCADGVVARAVSRLVTIATGLDPHGLGVPEVIWMRQPAEYHDAARRFAGGTPDGVAGWLLLCCGAMLDGAREALSIAESLSPG
>NZ_CP018300.1|WP_003419689.1|4073870_4074734_+|HAD-IB-family-hydrolase
MTVSDSPAQRQTPPQTPGGTAPRARTAAFFDLDKTIIAKSSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRTHLTNMCAGWDVAQVRSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVGPIARALGATHAMATRMIVEDGKYTGEVAFYCYGEGKAQAIRELAASEGYPLEHCYAYSDSITDLPMLEAVGHASVVNPDRGLRKEASVRGWPVLSFSRPVSLRDRIPAPSAAAIATTAAVGISALAAGAVTYALLRRFAFQP
>NZ_CP018300.1|WP_003419710.1|4085050_4085569_+|phage-holin-family-protein
MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRDVKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALLGFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW
>NZ_CP018300.1|WP_003419712.1|4085569_4086553_+|alpha/beta-hydrolase
MAAPDPSMTRIAGPWRHLDVHANGIRFHVVEAVPSGQPEGPDAATPPMQPALARPLVILLHGFGSFWWSWRHQLCGLTGARVVAVDLRGYGGSDKPPRGYDGWTLAGDTAGLIRALGHPSATLVGHADGGLACWTTALLHSRLVRAIALISSPHPAALRRSTLTRRDQRHALLPTLLRYQLPIWPERLLTRNNAAEIERLVRARGCAKWLASEDFSQAIDHLRQAIQIPAAAHCALEYQRWAVRSQLRSEGRRFIRAMTQQLGMPLLHLRGDADPYVLADPVERTQRYAPHGRYISIAGAGHFSHEEAPEEVNRHLMRFLEQVHQLS
>NZ_CP018300.1|WP_003900734.1|4086545_4087739_-|acid-resistance-serine-protease-MarP
MTPSQWLDIAVLAVAFIAAISGWRAGALGSMLSFGGVLLGATAGVLLAPHIVSQISAPRAKLFAALFLILALVVVGEVAGVVLGRAVRGAIRNRPIRLIDSVIGVGVQLVVVLTAAWLLAMPLTQSKEQPELAAAVKGSRVLARVNEAAPTWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPALVNNPVVAATEPSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTVYAGDKPFEATVVSYDPSVDVAILAVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDSGGPLIDLNGQVLGVVFGAAIDDAETGFVLTAGEVAGQLAKIGATQPVGTGACVS
>NZ_CP018300.1|WP_003419718.1|4087744_4088566_-|CoA-pyrophosphatase
MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDAYRRRLPADVLAMVTAAGAVSAMTSSRRDHREAAVLVLFSGPEAGPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALREANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAETAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVISAVLDVAGWAQPWDTGDIRELDAAMVLIDDESDPR
>NZ_CP018300.1|WP_003419721.1|4088697_4089381_-|TlpA-family-protein-disulfide-reductase
MPSLPTTPAETAMTTLTGKTRWTIAILAVVAALMAALVAQLHDYSASSTISQRPAPREHRDGDTPEALAWSRQRANLPPCPAAGNGPGAAALRGVVVVCAGDGSAVDVARALAGRRVVINLWAHWCAPCMTELPVMAEYQRRVGPAVLVVTVHQGQNEAAALSRLADLGVRLPTLQDDRRRVAAALRVANVMPATVVLRPDGSVAQTLPRAFGSADEIVAAVGNDAG
>NZ_CP018300.1|WP_003419724.1|4089380_4090118_-|endonuclease-III
MPGRWSAETRLALVRRARRMNRALAQAFPHVYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPLVQGPETDHLLALAGL
>NZ_CP018300.1|WP_003899635.1|4090225_4090603_+|hypothetical-protein
MFTLLVSWLLVACVPGLLMLATLGLGRLERFLARDTVTATDVAEFLEQAEAVDVHTLARNGMPEALDYLHRRQARRITDSPPLGSGAGPRYAGPLFVTDLDSPVEPPRHGQPNPQFRTARHANHV
>NZ_CP018300.1|WP_003419728.1|4090701_4091376_+|Crp/Fnr-family-transcriptional-regulator
MDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIADRPEISEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQLLQLAQRFGTQEGGALRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLEGKSVLISDSERLARRAR
>NZ_CP018300.1|WP_003419731.1|4091481_4092276_-|MBL-fold-metallo-hydrolase
MSKTAESLTHPAYGQLRAVTDTASVLLADNPGLLTLDGTNTWVLRGPLSDELVVVDPGPDDDEHLARVAALGRIALVLISHRHGDHTSGIDKLVALTGAPVRAADPQFLRRDGETLTDGEVIDVAGLTITVLATPGHTADSLSFVLDDAVLTADTVLGCGTTVIDKEDGSLADYLESLHRLRGLGRRTVLPGHGPDLLDLEAIASGYLLHRHERLEQIRAALRDLGDDATVREVVEHVYLDVDEKLWNAAEWSVQAQLDYLRTR
>NZ_CP018300.1|WP_003419733.1|4092282_4092738_-|RidA-family-protein
MSAKARLGQLGVTLPQVAAPLAAYVPAVRTGNLVYTAGQLPLEAGKLVRTGKLGADVNPEEGKTLARICALNALAAVDSLVDLDAVTRVVKVVGFVASAPGFHGQPSVINGASDLLAEVFGDSGAHARSAVGVSELPLDAPVEVELIVEVG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP018300_10	10.4\|2071554\|18\|NZ_CP018300\|CRT	2071554-2071571	18	NZ_CP018300.1	3903749-3903766	1	0.944
NZ_CP018300_10	10.4\|2071554\|18\|NZ_CP018300\|CRT	2071554-2071571	18	NZ_CP018300.1	3903845-3903862	1	0.944
NZ_CP018300_10	10.6\|2071653\|18\|NZ_CP018300\|CRT	2071653-2071670	18	NZ_CP018300.1	400543-400560	1	0.944
NZ_CP018300_10	10.6\|2071653\|18\|NZ_CP018300\|CRT	2071653-2071670	18	NZ_CP018300.1	603616-603633	1	0.944
NZ_CP018300_10	10.8\|2071743\|18\|NZ_CP018300\|CRT	2071743-2071760	18	NZ_CP018300.1	3435510-3435527	1	0.944
NZ_CP018300_1	1.5\|366203\|42\|NZ_CP018300\|CRISPRCasFinder	366203-366244	42	NZ_CP018300.1	374264-374305	2	0.952
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP018300.1	373079-373111	2	0.939
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP018300.1	836926-836946	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP018300.1	1855890-1855910	2	0.905
NZ_CP018300_3	3.9\|669569\|21\|NZ_CP018300\|CRISPRCasFinder	669569-669589	21	NZ_CP018300.1	2015088-2015108	2	0.905
NZ_CP018300_3	3.9\|669569\|21\|NZ_CP018300\|CRISPRCasFinder	669569-669589	21	NZ_CP018300.1	3907108-3907128	2	0.905
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	NZ_CP018300.1	671363-671398	2	0.944
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	NZ_CP018300.1	1209716-1209751	2	0.944
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	NZ_CP018300.1	2410487-2410522	2	0.944
NZ_CP018300_7	7.1\|1484818\|19\|NZ_CP018300\|PILER-CR	1484818-1484836	19	NZ_CP018300.1	399081-399099	2	0.895
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP018300.1	1207991-1208012	2	0.909

1. spacer 10.4|2071554|18|NZ_CP018300|CRT matches to position: 3903749-3903766, mismatch: 1, identity: 0.944

gaccagcagcgcgccgtt	CRISPR spacer
gatcagcagcgcgccgtt	Protospacer
**.***************

2. spacer 10.4|2071554|18|NZ_CP018300|CRT matches to position: 3903845-3903862, mismatch: 1, identity: 0.944

gaccagcagcgcgccgtt	CRISPR spacer
gatcagcagcgcgccgtt	Protospacer
**.***************

3. spacer 10.6|2071653|18|NZ_CP018300|CRT matches to position: 400543-400560, mismatch: 1, identity: 0.944

gatcagcccgacggcgtt	CRISPR spacer
gatcagcccgtcggcgtt	Protospacer
********** *******

4. spacer 10.6|2071653|18|NZ_CP018300|CRT matches to position: 603616-603633, mismatch: 1, identity: 0.944

gatcagcccgacggcgtt	CRISPR spacer
gatcagcccgtcggcgtt	Protospacer
********** *******

5. spacer 10.8|2071743|18|NZ_CP018300|CRT matches to position: 3435510-3435527, mismatch: 1, identity: 0.944

gatcagcgtcccgccggt	CRISPR spacer
gatcagcgtcccgctggt	Protospacer
**************.***

6. spacer 1.5|366203|42|NZ_CP018300|CRISPRCasFinder matches to position: 374264-374305, mismatch: 2, identity: 0.952

ccggtgcccgagttgaagaacccgatgtttccgctgccggag	CRISPR spacer
ccggtgcccgagttgaacaacccgacgtttccgctgccggag	Protospacer
***************** *******.****************

7. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to position: 373079-373111, mismatch: 2, identity: 0.939

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
aggctgccgaacccgatctggccgctgccggtg	Protospacer
********** *************.********

8. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to position: 836926-836946, mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
cccccgccggccccgccggtc	Protospacer
** ******** *********

9. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to position: 1855890-1855910, mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgacgttc	Protospacer
*************** ** **

10. spacer 3.9|669569|21|NZ_CP018300|CRISPRCasFinder matches to position: 2015088-2015108, mismatch: 2, identity: 0.905

gccccgctggggccggcgttg	CRISPR spacer
gccgcgctggggcaggcgttg	Protospacer
*** ********* *******

11. spacer 3.9|669569|21|NZ_CP018300|CRISPRCasFinder matches to position: 3907108-3907128, mismatch: 2, identity: 0.905

gccccgctggggccggcgttg	CRISPR spacer
gccccgctggcgccgccgttg	Protospacer
********** **** *****

12. spacer 5.17|922795|36|NZ_CP018300|CRT matches to position: 671363-671398, mismatch: 2, identity: 0.944

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gctgatgggcaacggcggcaacggcggggccggcgg	Protospacer
****** ***********.*****************

13. spacer 5.17|922795|36|NZ_CP018300|CRT matches to position: 1209716-1209751, mismatch: 2, identity: 0.944

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gctgatcggcaacggcggccacggcggggccggcgg	Protospacer
******************. ****************

14. spacer 5.17|922795|36|NZ_CP018300|CRT matches to position: 2410487-2410522, mismatch: 2, identity: 0.944

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gctgatcggcaacggcggcaacggcggtgccggcgg	Protospacer
******************.******** ********

15. spacer 7.1|1484818|19|NZ_CP018300|PILER-CR matches to position: 399081-399099, mismatch: 2, identity: 0.895

attggagaacagcccgccg	CRISPR spacer
attgccgaacagcccgccg	Protospacer
****  *************

16. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to position: 1207991-1208012, mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gttgccgatcagcccggcggca	Protospacer
**.********* *********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	38799-38819	0	1.0
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	35114-35134	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	40511-40531	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	45908-45928	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	51305-51325	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	56702-56722	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	61319-61339	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	65936-65956	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	85148-85168	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	90888-90908	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	97230-97250	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	102609-102629	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	107226-107246	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	113571-113591	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	118983-119003	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	125346-125366	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_005916	Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence	130761-130781	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	55866-55886	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	61281-61301	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	66696-66716	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	72117-72137	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	76740-76760	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	81363-81383	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	103420-103440	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	109154-109174	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	115532-115552	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	120965-120985	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	125588-125608	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	131930-131950	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	137348-137368	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	143711-143731	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	149123-149143	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	49875-49895	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	55290-55310	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	60705-60725	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	66102-66122	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	71535-71555	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	76152-76172	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	80769-80789	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	100048-100068	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	105782-105802	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	112142-112162	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	117557-117577	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	122174-122194	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	128534-128554	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	133945-133965	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	140326-140346	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	145738-145758	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MN304822	Phage 64_12, partial genome	25902-25922	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MN234185	Mycobacterium phage Lemuria, complete genome	22707-22727	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP012698	Microbacterium sp. No. 7 plasmid A, complete sequence	6291-6311	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP032156	Mycobacterium sp. ELW1 plasmid pELW1-1, complete sequence	83367-83387	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	133531-133551	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	28266-28286	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	81326-81346	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP007515	Rubrobacter radiotolerans strain RSPS-4 plasmid 1, complete sequence	97593-97613	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_019957	Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence	283242-283262	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1547156-1547176	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MF141540	Mycobacterium phage Avocado, complete genome	15446-15466	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MF141540	Mycobacterium phage Avocado, complete genome	24157-24177	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	KR080198	Mycobacterium phage Cambiare, complete genome	24622-24642	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	KR080197	Mycobacterium phage FlagStaff, complete genome	23986-24006	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MN234219	Mycobacterium phage Mercurio, complete genome	24939-24959	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_028791	Mycobacterium phage MOOREtheMARYer, complete genome	24148-24168	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MG770216	Mycobacterium phage Rem711, complete genome	26118-26138	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	KR080195	Mycobacterium phage Phayonce, complete genome	27606-27626	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	90206-90226	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	809956-809976	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP019460	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence	2921-2941	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP019460	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence	18392-18412	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	666684-666704	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	261208-261228	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	585241-585261	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_LR026982	Rhodoplanes piscinae isolate Rhod_plasmid plasmid 1, complete sequence	17307-17327	1	0.952
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP041045	Paracoccus sp. AK26 plasmid pAK1, complete sequence	281147-281167	1	0.952
NZ_CP018300_3	3.3\|669266\|21\|NZ_CP018300\|CRISPRCasFinder	669266-669286	21	MN813676	Arthrobacter phage Adolin, complete genome	41993-42013	1	0.952
NZ_CP018300_3	3.3\|669266\|21\|NZ_CP018300\|CRISPRCasFinder	669266-669286	21	MH834610	Arthrobacter phage DrManhattan, complete genome	41547-41567	1	0.952
NZ_CP018300_3	3.9\|669569\|21\|NZ_CP018300\|CRISPRCasFinder	669569-669589	21	NC_007766	Rhizobium etli CFN 42 plasmid p42f, complete sequence	143521-143541	1	0.952
NZ_CP018300_3	3.9\|669569\|21\|NZ_CP018300\|CRISPRCasFinder	669569-669589	21	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	1065182-1065202	1	0.952
NZ_CP018300_3	3.9\|669569\|21\|NZ_CP018300\|CRISPRCasFinder	669569-669589	21	NZ_CP020911	Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence	162077-162097	1	0.952
NZ_CP018300_3	3.9\|669569\|21\|NZ_CP018300\|CRISPRCasFinder	669569-669589	21	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	1042882-1042902	1	0.952
NZ_CP018300_3	3.9\|669569\|21\|NZ_CP018300\|CRISPRCasFinder	669569-669589	21	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	1065182-1065202	1	0.952
NZ_CP018300_3	3.13\|669764\|21\|NZ_CP018300\|CRISPRCasFinder	669764-669784	21	NZ_CP015740	Shinella sp. HZN7 plasmid pShin-04, complete sequence	73347-73367	1	0.952
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1975819-1975840	1	0.955
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1109892-1109913	1	0.955
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP016457	Sphingobium sp. RAC03 plasmid pBSY17_2, complete sequence	87869-87890	1	0.955
NZ_CP018300_8	8.15\|1567543\|22\|NZ_CP018300\|CRISPRCasFinder	1567543-1567564	22	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	362668-362689	1	0.955
NZ_CP018300_8	8.15\|1567543\|22\|NZ_CP018300\|CRISPRCasFinder	1567543-1567564	22	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2289382-2289403	1	0.955
NZ_CP018300_8	8.15\|1567543\|22\|NZ_CP018300\|CRISPRCasFinder	1567543-1567564	22	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	81656-81677	1	0.955
NZ_CP018300_8	8.15\|1567543\|22\|NZ_CP018300\|CRISPRCasFinder	1567543-1567564	22	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	56160-56181	1	0.955
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	74171-74191	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	268359-268379	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	333813-333833	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP029209	Nitratireductor sp. OM-1 plasmid pOM-1, complete sequence	585652-585672	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NC_016588	Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence	98693-98713	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MN234219	Mycobacterium phage Mercurio, complete genome	23317-23337	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	MK494105	Mycobacterium phage Pinnie, complete genome	15910-15930	2	0.905
NZ_CP018300_2	2.2\|668999\|21\|NZ_CP018300\|CRISPRCasFinder	668999-669019	21	NZ_CP019037	Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence	396863-396883	2	0.905
NZ_CP018300_8	8.2\|1566617\|22\|NZ_CP018300\|CRISPRCasFinder	1566617-1566638	22	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	881140-881161	2	0.909
NZ_CP018300_8	8.2\|1566617\|22\|NZ_CP018300\|CRISPRCasFinder	1566617-1566638	22	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	225972-225993	2	0.909
NZ_CP018300_8	8.2\|1566617\|22\|NZ_CP018300\|CRISPRCasFinder	1566617-1566638	22	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	451168-451189	2	0.909
NZ_CP018300_8	8.2\|1566617\|22\|NZ_CP018300\|CRISPRCasFinder	1566617-1566638	22	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	234992-235013	2	0.909
NZ_CP018300_8	8.2\|1566617\|22\|NZ_CP018300\|CRISPRCasFinder	1566617-1566638	22	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	597449-597470	2	0.909
NZ_CP018300_8	8.3\|1566671\|22\|NZ_CP018300\|CRISPRCasFinder	1566671-1566692	22	NZ_CP025510	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence	117076-117097	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	448838-448859	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	160471-160492	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP021028	Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence	175264-175285	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP013634	Rhizobium sp. N324 plasmid pRspN324d, complete sequence	457593-457614	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP013503	Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence	166709-166730	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP013509	Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence	166709-166730	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP013520	Rhizobium sp. N113 plasmid pRspN113c, complete sequence	166709-166730	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP013493	Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence	166709-166730	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP013516	Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence	164465-164486	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	97458-97479	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP012698	Microbacterium sp. No. 7 plasmid A, complete sequence	53118-53139	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	100830-100851	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	307854-307875	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	23841-23862	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	279961-279982	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	359201-359222	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	606826-606847	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	411558-411579	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	300111-300132	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	483830-483851	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP024312	Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence	68146-68167	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	175112-175133	2	0.909
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	314082-314103	2	0.909
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	402883-402907	2	0.92
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	416172-416196	2	0.92
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	472935-472959	2	0.92
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4024254-4024277	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4460576-4460599	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP034768	Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence	122201-122224	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	37773-37796	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_AP019631	Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence	116652-116675	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_AP019631	Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence	72348-72371	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	KU716094	Mycobacterium phage Eidsmoe, complete genome	5649-5672	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MH371122	Mycobacterium phage Priya, complete genome	5650-5673	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MK016502	Mycobacterium phage Pat3, complete genome	22827-22850	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MK937593	Mycobacterium phage Flypotenuse, complete genome	23717-23740	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MG872835	Mycobacterium phage Conquerage, complete genome	5649-5672	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MH536820	Mycobacterium phage Glexan, complete genome	23717-23740	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	91001-91024	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP013426	Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence	44795-44818	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1701753-1701776	3	0.875
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MH271298	Microbacterium phage Floof, complete genome	37939-37962	3	0.875
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_KY349138	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence	9264-9285	3	0.864
NZ_CP018300_8	8.4\|1566725\|22\|NZ_CP018300\|CRISPRCasFinder	1566725-1566746	22	NZ_CP021649	Acidovorax sp. T1 plasmid p1-T1, complete sequence	13233-13254	3	0.864
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	937294-937318	3	0.88
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	1470762-1470786	3	0.88
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	MN586053	Arthrobacter phage BeatusComedenti, complete genome	26689-26713	3	0.88
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NC_031254	Arthrobacter phage Kitkat, complete genome	26809-26833	3	0.88
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NC_031231	Arthrobacter phage KellEzio, complete genome	26691-26715	3	0.88
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	633177-633201	3	0.88
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP030129	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed3, complete sequence	74124-74148	3	0.88
NZ_CP018300_8	8.15\|1567543\|22\|NZ_CP018300\|CRISPRCasFinder	1567543-1567564	22	NC_008270	Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence	380879-380900	3	0.864
NZ_CP018300_10	10.9\|2071782\|24\|NZ_CP018300\|CRT	2071782-2071805	24	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	1555522-1555545	3	0.875
NZ_CP018300_10	10.9\|2071782\|24\|NZ_CP018300\|CRT	2071782-2071805	24	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	1560190-1560213	3	0.875
NZ_CP018300_1	1.1\|365948\|27\|NZ_CP018300\|CRISPRCasFinder	365948-365974	27	NC_023591	Mycobacterium phage Adler, complete genome	61249-61275	4	0.852
NZ_CP018300_1	1.1\|365948\|27\|NZ_CP018300\|CRISPRCasFinder	365948-365974	27	KF981876	UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome	61247-61273	4	0.852
NZ_CP018300_1	1.7\|366344\|27\|NZ_CP018300\|CRISPRCasFinder	366344-366370	27	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	10066-10092	4	0.852
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	460464-460490	4	0.852
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NC_016652	Rhodococcus phage REQ2, complete genome	36035-36061	4	0.852
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	KY945355	Mycobacterium phage Shandong1, complete genome	25634-25660	4	0.852
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_CP015095	Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence	106725-106751	4	0.852
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NC_041888	Mycobacterium phage Tortellini, complete genome	37216-37242	4	0.852
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1096460-1096489	4	0.867
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1898211-1898234	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP025431	Paracoccus zhejiangensis strain J6 plasmid pPZ01, complete sequence	261506-261529	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	673134-673157	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP016822	Rhodococcus sp. p52 plasmid pDF03, complete sequence	60076-60099	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MN582086	Siphoviridae sp. ctdEk19, complete genome	33324-33347	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MF919502	Mycobacterium phage Demsculpinboyz, complete genome	21980-22003	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MT889380	Mycobacterium phage Coco12, complete genome	22623-22646	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NC_023698	Mycobacterium phage Avani, complete genome	21987-22010	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MT114167	Mycobacterium phage Phanphagia, complete genome	22278-22301	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	558871-558894	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1500559-1500582	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	295932-295955	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	1116335-1116358	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MN096355	Mycobacterium phage Purky, complete genome	48975-48998	4	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	MK279853	Gordonia phage Gray, complete genome	68404-68427	4	0.833
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	818773-818800	4	0.857
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	420542-420569	4	0.857
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	77799-77826	4	0.857
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP021372	Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence	176640-176664	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	LR134127	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7	29428-29452	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	LR134127	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7	38191-38215	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	MT553342	Microbacterium phage Kelcole, complete genome	51573-51597	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NC_048068	Microbacterium phage OneinaGillian, complete genome	50894-50918	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	MT310894	Microbacterium phage Tempo, complete genome	51697-51721	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP047175	Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence	42080-42104	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	67777-67801	4	0.84
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	MN034284	Leviviridae sp. isolate H2_Rhizo_Litter_49_scaffold_25938 sequence	624-648	4	0.84
NZ_CP018300_8	8.14\|1567486\|25\|NZ_CP018300\|CRISPRCasFinder	1567486-1567510	25	MN582064	Podoviridae sp. ctka020, complete genome	29274-29298	4	0.84
NZ_CP018300_10	10.9\|2071782\|24\|NZ_CP018300\|CRT	2071782-2071805	24	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	680430-680453	4	0.833
NZ_CP018300_10	10.9\|2071782\|24\|NZ_CP018300\|CRT	2071782-2071805	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5913119-5913142	4	0.833
NZ_CP018300_10	10.9\|2071782\|24\|NZ_CP018300\|CRT	2071782-2071805	24	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	143186-143209	4	0.833
NZ_CP018300_1	1.1\|365948\|27\|NZ_CP018300\|CRISPRCasFinder	365948-365974	27	LR794124	Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1	34861-34887	5	0.815
NZ_CP018300_1	1.1\|365948\|27\|NZ_CP018300\|CRISPRCasFinder	365948-365974	27	NC_012662	Vibrio phage VP93, complete genome	35301-35327	5	0.815
NZ_CP018300_1	1.7\|366344\|27\|NZ_CP018300\|CRISPRCasFinder	366344-366370	27	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	2189-2215	5	0.815
NZ_CP018300_1	1.7\|366344\|27\|NZ_CP018300\|CRISPRCasFinder	366344-366370	27	MN693945	Marine virus AFVG_250M952, complete genome	34909-34935	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	369429-369455	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	338832-338858	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	363377-363403	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP015368	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence	104717-104743	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	338543-338569	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	340811-340837	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	342690-342716	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	343060-343086	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	355714-355740	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	343060-343086	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	348335-348361	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	343052-343078	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP020444	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence	69464-69490	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	363377-363403	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	355714-355740	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	342690-342716	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP044078	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence	10340-10366	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP031081	Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence	19365-19391	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MN586031	Gordonia phage Gambino, complete genome	3053-3079	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	KU998236	Gordonia phage Blueberry, complete genome	3053-3079	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MN062704	Gordonia phage JuJu, complete genome	3063-3089	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MK501729	Gordonia phage Walrus, complete genome	3053-3079	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NC_031226	Gordonia phage BaxterFox, complete genome	2982-3008	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MK967393	Rhodococcus phage Whack, complete genome	3063-3089	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MT723935	Gordonia phage Azula, complete genome	3053-3079	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	KU963249	Gordonia phage Yeezy, complete genome	2982-3008	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MH153808	Gordonia phage Petra, complete genome	3053-3079	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MT639650	Gordonia phage Ohgeesy, complete genome	2982-3008	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MH536818	Gordonia phage Frokostdame, complete genome	3055-3081	5	0.815
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	KX557275	Gordonia phage CarolAnn, complete genome	3052-3078	5	0.815
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	KX683875	Mycobacterium phage Baehexic, complete genome	12181-12207	5	0.815
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	KM197169	Mycobacterium phage Piro94, complete genome	12178-12204	5	0.815
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	MF668269	Mycobacterium phage Drake55, complete genome	12177-12203	5	0.815
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	MK284522	Mycobacterium phage Malec, complete genome	11950-11976	5	0.815
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	KM677210	Mycobacterium phage Larenn, complete genome	11945-11971	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_CP022264	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence	1800-1826	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_CP022264	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence	136919-136945	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	658056-658082	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1514868-1514894	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5852040-5852066	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_CP049908	Hymenobacter sp. HDW8 plasmid p_unnamed1, complete sequence	235006-235032	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_CP049700	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence	263243-263269	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	MH576962	Streptomyces phage Satis, complete genome	95306-95332	5	0.815
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	MK620894	Streptomyces phage Kradal, complete genome	95310-95336	5	0.815
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1068923-1068952	5	0.833
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	1739900-1739929	5	0.833
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	233389-233418	5	0.833
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP031193	Humibacter sp. BT305 plasmid unnamed1	44938-44967	5	0.833
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP050092	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence	137673-137702	5	0.833
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	984252-984281	5	0.833
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1598936-1598965	5	0.833
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	233398-233427	5	0.833
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	292905-292934	5	0.833
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	AY950802	Haloarcula phage SH1, complete genome	16104-16133	5	0.833
NZ_CP018300_5	5.16\|922753\|24\|NZ_CP018300\|CRT	922753-922776	24	NC_006911	Streptomyces sp. F11 plasmid pFP11, complete sequence	11649-11672	5	0.792
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NZ_LN907828	Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence	94483-94510	5	0.821
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	KU728633	Mycobacterium phage Bipper, complete genome	41992-42019	5	0.821
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	MK977701	Mycobacterium phage Cracklewink, complete genome	41985-42012	5	0.821
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	100320-100347	5	0.821
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP025013	Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence	614111-614135	5	0.8
NZ_CP018300_8	8.5\|1566779\|25\|NZ_CP018300\|CRISPRCasFinder	1566779-1566803	25	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	92705-92729	5	0.8
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NC_018746	Pseudomonas putida ND6 plasmid pND6-2, complete sequence	45440-45470	5	0.839
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	MN961671	Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence	123562-123592	5	0.839
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	MN961672	Pseudomonas aeruginosa strain PA15W plasmid pPA15W-NR, complete sequence	72551-72581	5	0.839
NZ_CP018300_8	8.13\|1567420\|34\|NZ_CP018300\|CRISPRCasFinder	1567420-1567453	34	NC_006362	Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence	89410-89443	5	0.853
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NC_010850	Rhodococcus sp. NS1 plasmid pNSL1, complete sequence	92901-92931	5	0.839
NZ_CP018300_1	1.1\|365948\|27\|NZ_CP018300\|CRISPRCasFinder	365948-365974	27	NZ_CP045917	Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence	207335-207361	6	0.778
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	435770-435802	6	0.818
NZ_CP018300_1	1.7\|366344\|27\|NZ_CP018300\|CRISPRCasFinder	366344-366370	27	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	32942-32968	6	0.778
NZ_CP018300_1	1.9\|366494\|27\|NZ_CP018300\|CRISPRCasFinder	366494-366520	27	NC_009959	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence	50750-50776	6	0.778
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	179708-179734	6	0.778
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4846911-4846937	6	0.778
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	78863-78889	6	0.778
NZ_CP018300_1	1.10\|366554\|27\|NZ_CP018300\|CRISPRCasFinder	366554-366580	27	MK494099	Mycobacterium phage Typha, complete genome	33831-33857	6	0.778
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	GQ141189	Bifidobacterium phage Bbif-1, complete sequence	38062-38092	6	0.806
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	658647-658673	6	0.778
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	NC_023606	Mycobacterium phage CRB1, complete genome	11649-11675	6	0.778
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	MK524491	Mycobacterium phage Whabigail7, complete genome	12139-12165	6	0.778
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	KX619650	Mycobacterium phage Jerm, complete genome	12089-12115	6	0.778
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	MN585998	Mycobacterium phage Bugsy, complete genome	12128-12154	6	0.778
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	JN408460	Mycobacterium phage Turbido, complete genome	12151-12177	6	0.778
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	MH077576	Mycobacterium phage AbbyPaige, complete genome	12129-12155	6	0.778
NZ_CP018300_5	5.5\|922258\|27\|NZ_CP018300\|CRT	922258-922284	27	MH825704	Mycobacterium phage LilTurb, complete genome	12148-12174	6	0.778
NZ_CP018300_5	5.10\|922468\|27\|NZ_CP018300\|CRT	922468-922494	27	NZ_AP021845	Azospira sp. I09 plasmid pAZI09, complete sequence	147990-148016	6	0.778
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	508-537	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	280809-280838	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	561652-561681	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP050083	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence	554428-554457	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP049733	Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence	542116-542145	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	610786-610815	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	571170-571199	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1563589-1563618	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	421135-421164	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1217050-1217079	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1265979-1266008	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1135414-1135443	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP037868	Hydrogenophaga pseudoflava strain DSM 1084 plasmid pDSM1084, complete sequence	5790-5819	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1195134-1195163	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1134511-1134540	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	762260-762289	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1168711-1168740	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1168700-1168729	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1135406-1135435	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1134762-1134791	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1135397-1135426	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1217165-1217194	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1217149-1217178	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1217142-1217171	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_019408	Caulobacter phage CcrRogue, complete genome	180466-180495	6	0.8
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	174181-174210	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP017941	Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence	270228-270257	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	MK937608	Microbacterium phage Cressida, complete genome	54022-54051	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP050083	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence	554437-554466	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP049733	Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence	542125-542154	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP017592	Pantoea stewartii subsp. stewartii DC283 plasmid ppDSJ01, complete sequence	7337-7366	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP008898	Enterobacter hormaechei subsp. hoffmannii ECNIH3 plasmid pENT-576, complete sequence	43955-43984	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP023489	Klebsiella pneumoniae subsp. pneumoniae strain ST101:960186733 plasmid p19-10_02, complete sequence	73653-73682	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP043515	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed4, complete sequence	36331-36360	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	571179-571208	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_LT984809	Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence	317155-317184	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP026371	Klebsiella quasipneumoniae strain A708 plasmid pA708-3, complete sequence	116386-116415	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP050069	Klebsiella aerogenes strain 035 plasmid p035_A-VIM-1, complete sequence	79588-79617	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP039425	Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence	132572-132601	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP009856	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-784, complete sequence	26128-26157	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP039430	Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence	132570-132599	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP040937	Hymenobacter sp. DG01 plasmid unnamed, complete sequence	32030-32059	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	14031-14060	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	17715-17744	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP006588	Hymenobacter sp. APR13 plasmid pHA, complete sequence	19031-19060	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1930897-1930926	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	190353-190382	6	0.8
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	MH029534	Myoviridae environmental samples clone NHS-Seq2, complete sequence	34123-34152	6	0.8
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	MT723940	Mycobacterium phage Ellie, complete genome	24126-24161	6	0.833
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NZ_AP022571	Mycolicibacterium poriferae strain JCM 12603 plasmid pJCM12603, complete sequence	39276-39303	6	0.786
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NC_008703	Mycobacterium sp. KMS plasmid pMKMS01, complete sequence	76834-76861	6	0.786
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NZ_LR594663	Variovorax sp. RA8 plasmid 2	131793-131820	6	0.786
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	27764-27794	6	0.806
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	438646-438676	6	0.806
NZ_CP018300_8	8.13\|1567420\|34\|NZ_CP018300\|CRISPRCasFinder	1567420-1567453	34	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	28989-29022	6	0.824
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NC_009478	Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence	8328-8358	6	0.806
NZ_CP018300_1	1.4\|366143\|27\|NZ_CP018300\|CRISPRCasFinder	366143-366169	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	48081-48107	7	0.741
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MK977708	Mycobacterium phage Fulbright, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MG099948	Mycobacterium phage Philonius, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MH926055	Mycobacterium phage Chewbacca, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MT723932	Mycobacterium phage Schnauzer, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	KU935726	Mycobacterium phage Xerxes, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	KU935730	Mycobacterium phage Pipsqueaks, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MH316570	Mycobacterium phage Silvafighter, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MK524518	Mycobacterium phage Smurph, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MK524515	Mycobacterium phage Parmesanjohn, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MH697585	Mycobacterium phage Gex, complete genome	10280-10310	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	KM588359	Mycobacterium phage Carcharodon, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MH697576	Mycobacterium phage Aggie, complete genome	10282-10312	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MH697593	Mycobacterium phage Tapioca, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	MG099936	Mycobacterium phage Andies, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	NC_031243	Mycobacterium phage Xeno, complete genome	10281-10311	7	0.774
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	JN256079	Mycobacterium phage Charlie, complete genome	10281-10311	7	0.774
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	943873-943902	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	392100-392129	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1838430-1838459	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	616186-616215	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	397449-397478	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1703655-1703684	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	212329-212358	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	679499-679528	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1744018-1744047	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1760732-1760761	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	178925-178954	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	75369-75398	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	153012-153041	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	589998-590027	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	81538-81567	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	845884-845913	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	258296-258325	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1723933-1723962	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1859622-1859651	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1841724-1841753	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1841724-1841753	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	137321-137350	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	258496-258525	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	257917-257946	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	234345-234374	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	461507-461536	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	254201-254230	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	236985-237014	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	298368-298397	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	258487-258516	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	461579-461608	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	390422-390451	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1964821-1964850	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	461516-461545	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	237930-237959	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	849014-849043	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1227007-1227036	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	238244-238273	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	245279-245308	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	235437-235466	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	126762-126791	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	234570-234599	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	258309-258338	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	231309-231338	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	235690-235719	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	238261-238290	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	252665-252694	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	236955-236984	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	251052-251081	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	298440-298469	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	230351-230380	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	252665-252694	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	236955-236984	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	461938-461967	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	252665-252694	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	438995-439024	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	230352-230381	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	252665-252694	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	236955-236984	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	236955-236984	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	236955-236984	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	230352-230381	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	245262-245291	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	245236-245265	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	241864-241893	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	240004-240033	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	235466-235495	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	230352-230381	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	252665-252694	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	280525-280554	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	251050-251079	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	230352-230381	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	230352-230381	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	236955-236984	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	HM560026	Uncultured bacterium plasmid pTRACA45, complete sequence	1764-1793	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_010867	Neisseria lactamica plasmid pNL3.1, complete sequence	3216-3245	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	121720-121749	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	535160-535189	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	326858-326887	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	121664-121693	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	KT997827	Uncultured Mediterranean phage uvDeep-CGR0-KM15-C219, complete genome	28429-28458	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	235977-236006	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1424992-1425021	7	0.767
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	KT997829	Uncultured Mediterranean phage uvDeep-CGR0-KM22-C158, complete genome	24686-24715	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013634	Rhizobium sp. N324 plasmid pRspN324d, complete sequence	278785-278814	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP035001	Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence	113824-113853	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	158849-158878	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	384914-384943	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	317121-317150	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP020909	Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence	385410-385439	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	260932-260961	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP020951	Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence	329309-329338	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NC_021908	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence	391416-391445	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP020441	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence	243975-244004	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	301676-301705	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP044080	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence	201076-201105	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	635292-635321	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	422833-422862	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	494408-494437	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	MN582086	Siphoviridae sp. ctdEk19, complete genome	33318-33347	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	864583-864612	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP022700	Acetobacter tropicalis strain BDGP1 plasmid pAtBDGP1A, complete sequence	61493-61522	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1238691-1238720	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	1484042-1484071	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	1466967-1466996	7	0.767
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP031082	Paracoccus yeei strain CCUG 32053 plasmid pYEE4, complete sequence	119508-119537	7	0.767
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	NC_022087	Mycobacterium phage AnnaL29, complete genome	5558-5593	7	0.806
NZ_CP018300_8	8.1\|1566557\|28\|NZ_CP018300\|CRISPRCasFinder	1566557-1566584	28	NC_010553	Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence	259627-259654	7	0.75
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP041045	Paracoccus sp. AK26 plasmid pAK1, complete sequence	281800-281830	7	0.774
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	CP017041	Propionibacterium sp. oral taxon 193 strain F0672 plasmid unnamed1, complete sequence	68407-68437	7	0.774
NZ_CP018300_10	10.7\|2071692\|30\|NZ_CP018300\|CRT	2071692-2071721	30	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	52187-52216	7	0.767
NZ_CP018300_10	10.7\|2071692\|30\|NZ_CP018300\|CRT	2071692-2071721	30	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	75140-75169	7	0.767
NZ_CP018300_10	10.7\|2071692\|30\|NZ_CP018300\|CRT	2071692-2071721	30	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	376489-376518	7	0.767
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	147567-147597	7	0.774
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	36995-37025	7	0.774
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP042263	Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence	372247-372277	7	0.774
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1386736-1386768	8	0.758
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	35126-35158	8	0.758
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1241611-1241643	8	0.758
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	275839-275871	8	0.758
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	310597-310629	8	0.758
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2714450-2714479	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	837910-837939	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	424702-424731	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	975216-975245	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1013021-1013050	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_KY126370	Enterobacter cloacae subsp. cloacae strain MN201516 plasmid pOP-I, complete sequence	93253-93282	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP054625	Cupriavidus gilardii strain FDAARGOS_639 plasmid unnamed1, complete sequence	22400-22429	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1889334-1889363	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_LT960615	Hartmannibacter diazotrophicus strain E19T plasmid HDIAp1, complete sequence	21202-21231	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP046347	Citrobacter portucalensis strain FDAARGOS_738 plasmid unnamed1, complete sequence	30108-30137	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP044100	Citrobacter werkmanii strain FDAARGOS_616 plasmid unnamed1, complete sequence	32856-32885	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP032156	Mycobacterium sp. ELW1 plasmid pELW1-1, complete sequence	111116-111145	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	KY555144	Caulobacter phage Ccr5, complete genome	178242-178271	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_KP873172	Pseudomonas aeruginosa PAO1 plasmid pAMBL1, complete sequence	21059-21088	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP045203	Citrobacter sp. NMI7904_11 plasmid pCTEL-2, complete sequence	159096-159125	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NC_021492	Enterobacter sp. R4-368 plasmid pENT01, complete sequence	50097-50126	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP022156	Escherichia coli strain ABWA45 plasmid pABWA45_2, complete sequence	15249-15278	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP024682	Citrobacter freundii strain UMH14 plasmid pUMH14_2, complete sequence	41943-41972	8	0.733
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	242723-242752	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	28649-28678	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	310870-310899	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	462801-462830	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	292109-292138	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	287383-287412	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	292305-292334	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	292675-292704	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	306458-306487	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	292675-292704	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	295900-295929	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	292670-292699	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	306458-306487	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	292305-292334	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	298287-298316	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1682210-1682239	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	294530-294559	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_LR134452	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence	375826-375855	8	0.733
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	112972-113001	8	0.733
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	MG770216	Mycobacterium phage Rem711, complete genome	26292-26327	8	0.778
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	KY087993	Mycobacterium phage Hammy, complete genome	24359-24394	8	0.778
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	MF140406	Mycobacterium phage DarthP, complete genome	24368-24403	8	0.778
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	349053-349083	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP039899	Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence	336247-336277	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP039913	Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence	262996-263026	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP039890	Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence	336247-336277	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP018001	Rhizobium sp. Y9 plasmid pY9, complete sequence	264529-264559	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NC_022536	Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence	458177-458207	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP053858	Rhizobium pusense strain 76 plasmid pR76, complete sequence	311056-311086	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	88587-88617	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	CP036360	Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence	284157-284187	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	300067-300097	8	0.742
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1510497-1510527	8	0.742
NZ_CP018300_10	10.7\|2071692\|30\|NZ_CP018300\|CRT	2071692-2071721	30	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	9194-9223	8	0.733
NZ_CP018300_10	10.7\|2071692\|30\|NZ_CP018300\|CRT	2071692-2071721	30	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	983284-983313	8	0.733
NZ_CP018300_13	13.6\|3106519\|29\|NZ_CP018300\|PILER-CR	3106519-3106547	29	MK599315	Pseudomonas phage PA1C, complete genome	299172-299200	8	0.724
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	CP033373	Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence	12237-12267	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1260343-1260373	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1009358-1009388	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1260501-1260531	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1009351-1009381	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	756669-756699	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1137767-1137797	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1009365-1009395	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1260057-1260087	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1260001-1260031	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	981946-981976	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	938267-938297	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	748414-748444	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	896022-896052	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	215713-215743	8	0.742
NZ_CP018300_14	14.7\|3725324\|31\|NZ_CP018300\|CRT	3725324-3725354	31	NC_014213	Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence	111748-111778	8	0.742
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	91175-91207	9	0.727
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	668963-668995	9	0.727
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	789706-789738	9	0.727
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	625853-625885	9	0.727
NZ_CP018300_3	3.12\|669704\|36\|NZ_CP018300\|CRISPRCasFinder	669704-669739	36	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	170846-170881	9	0.75
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	NZ_CP014964	Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence	13698-13728	9	0.71
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	NC_015974	Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence	20960-20990	9	0.71
NZ_CP018300_4	4.1\|688318\|31\|NZ_CP018300\|CRISPRCasFinder	688318-688348	31	NZ_CP005085	Sphingobium sp. TKS plasmid pTK1, complete sequence	15390-15420	9	0.71
NZ_CP018300_5	5.13\|922609\|30\|NZ_CP018300\|CRT	922609-922638	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5046041-5046070	9	0.7
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NC_005241	Cupriavidus necator H16 megaplasmid pHG1, complete sequence	65937-65966	9	0.7
NZ_CP018300_5	5.15\|922705\|30\|NZ_CP018300\|CRT	922705-922734	30	NZ_CP039289	Cupriavidus necator H16 plasmid pHG1, complete sequence	65937-65966	9	0.7
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	MF140398	Mycobacterium phage Amohnition, complete genome	24446-24481	9	0.75
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	345043-345073	9	0.71
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	245050-245080	9	0.71
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NC_022049	Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence	194387-194417	9	0.71
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	MN234199	Mycobacterium phage Ekdilam, complete genome	24235-24265	9	0.71
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	1145162-1145192	9	0.71
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	453136-453166	9	0.71
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP013740	Streptomyces globisporus C-1027 plasmid pSGL1, complete sequence	2806-2836	9	0.71
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1908459-1908489	9	0.71
NZ_CP018300_14	14.5\|3725183\|34\|NZ_CP018300\|CRT	3725183-3725216	34	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	922290-922323	9	0.735
NZ_CP018300_14	14.5\|3725183\|34\|NZ_CP018300\|CRT	3725183-3725216	34	MG812496	Gordonia phage SallySpecial, complete genome	7675-7708	9	0.735
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	91179-91211	10	0.697
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	90245-90277	10	0.697
NZ_CP018300_1	1.6\|366278\|33\|NZ_CP018300\|CRISPRCasFinder	366278-366310	33	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	99166-99198	10	0.697
NZ_CP018300_5	5.2\|922105\|39\|NZ_CP018300\|CRT	922105-922143	39	NZ_CP044080	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence	107058-107096	10	0.744
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	MN369764	Mycobacterium phage Rahalelujah, complete genome	24340-24375	10	0.722
NZ_CP018300_5	5.17\|922795\|36\|NZ_CP018300\|CRT	922795-922830	36	NZ_CP025548	Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence	25147-25182	10	0.722
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	425898-425928	10	0.677
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	344090-344120	10	0.677
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	68383-68413	10	0.677
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	16322-16352	10	0.677
NZ_CP018300_8	8.10\|1567171\|31\|NZ_CP018300\|CRISPRCasFinder	1567171-1567201	31	NZ_AP014581	Burkholderia sp. RPE67 plasmid p3, complete sequence	131907-131937	10	0.677
NZ_CP018300_8	8.13\|1567420\|34\|NZ_CP018300\|CRISPRCasFinder	1567420-1567453	34	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	1081518-1081551	10	0.706
NZ_CP018300_12	12.9\|3104026\|35\|NZ_CP018300\|PILER-CR,CRISPRCasFinder,CRT	3104026-3104060	35	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	414652-414686	10	0.714
NZ_CP018300_13	13.18\|3107396\|34\|NZ_CP018300\|PILER-CR	3107396-3107429	34	NZ_AP022335	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence	171698-171731	10	0.706
NZ_CP018300_13	13.34\|3107392\|34\|NZ_CP018300\|CRISPRCasFinder,CRT	3107392-3107425	34	NZ_AP022335	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence	171698-171731	10	0.706
NZ_CP018300_14	14.5\|3725183\|34\|NZ_CP018300\|CRT	3725183-3725216	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	470079-470112	10	0.706
NZ_CP018300_14	14.5\|3725183\|34\|NZ_CP018300\|CRT	3725183-3725216	34	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	68774-68807	10	0.706
NZ_CP018300_14	14.5\|3725183\|34\|NZ_CP018300\|CRT	3725183-3725216	34	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NZ_CP018300_14	14.5\|3725183\|34\|NZ_CP018300\|CRT	3725183-3725216	34	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NZ_CP018300_14	14.9\|3725456\|37\|NZ_CP018300\|CRT	3725456-3725492	37	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	975062-975098	10	0.73
NZ_CP018300_14	14.5\|3725183\|34\|NZ_CP018300\|CRT	3725183-3725216	34	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	326578-326611	11	0.676

1. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 0, identity: 1.0

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtc	Protospacer
*********************

2. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

3. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

4. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

5. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

6. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

7. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

8. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

9. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

10. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

11. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

12. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

13. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

14. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

15. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

16. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

17. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_005916 (Mycobacterium ulcerans Agy99 plasmid pMUM001, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

18. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

19. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

20. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

21. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

22. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

23. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

24. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

25. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

26. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

27. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

28. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

29. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

30. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

31. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

32. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

33. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

34. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

35. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

36. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

37. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

38. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

39. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

40. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

41. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

42. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

43. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

44. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

45. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

46. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

47. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

48. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

49. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MN304822 (Phage 64_12, partial genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
acgccgccggcgccgccggtc	Protospacer
 ********************

50. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MN234185 (Mycobacterium phage Lemuria, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

51. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP012698 (Microbacterium sp. No. 7 plasmid A, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtt	Protospacer
********************.

52. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032156 (Mycobacterium sp. ELW1 plasmid pELW1-1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggtg	Protospacer
********************

53. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccgctc	Protospacer
****************** **

54. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccgctc	Protospacer
****************** **

55. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccgctc	Protospacer
****************** **

56. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP007515 (Rubrobacter radiotolerans strain RSPS-4 plasmid 1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgcaggtc	Protospacer
**************** ****

57. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_019957 (Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ctgccgccggcgccgccggtc	Protospacer
*.*******************

58. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccgccgccgccggtc	Protospacer
********* ***********

59. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MF141540 (Mycobacterium phage Avocado, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggcc	Protospacer
*******************.*

60. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MF141540 (Mycobacterium phage Avocado, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgcccgtc	Protospacer
***************** ***

61. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to KR080198 (Mycobacterium phage Cambiare, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgcccgtc	Protospacer
***************** ***

62. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to KR080197 (Mycobacterium phage FlagStaff, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgcccgtc	Protospacer
***************** ***

63. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MN234219 (Mycobacterium phage Mercurio, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccgttc	Protospacer
****************** **

64. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_028791 (Mycobacterium phage MOOREtheMARYer, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgcccgtc	Protospacer
***************** ***

65. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MG770216 (Mycobacterium phage Rem711, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggcc	Protospacer
*******************.*

66. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to KR080195 (Mycobacterium phage Phayonce, complete genome) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccgccgccgccggtc	Protospacer
********* ***********

67. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgctggtc	Protospacer
****************.****

68. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgacggtc	Protospacer
*************** *****

69. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP019460 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccgccgccgccggtc	Protospacer
********* ***********

70. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP019460 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccgccgccgccggtc	Protospacer
********* ***********

71. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggctccgccggtc	Protospacer
*********** *********

72. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgcccgcgccgccggtc	Protospacer
******** ************

73. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccgccgccgccggtc	Protospacer
********* ***********

74. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_LR026982 (Rhodoplanes piscinae isolate Rhod_plasmid plasmid 1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
cagccgccggcgccgccggtc	Protospacer
* *******************

75. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP041045 (Paracoccus sp. AK26 plasmid pAK1, complete sequence) position: , mismatch: 1, identity: 0.952

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggtgccgccggtc	Protospacer
**********.**********

76. spacer 3.3|669266|21|NZ_CP018300|CRISPRCasFinder matches to MN813676 (Arthrobacter phage Adolin, complete genome) position: , mismatch: 1, identity: 0.952

tctccgccattgccgcccgct	CRISPR spacer
tcgccgccattgccgcccgct	Protospacer
** ******************

77. spacer 3.3|669266|21|NZ_CP018300|CRISPRCasFinder matches to MH834610 (Arthrobacter phage DrManhattan, complete genome) position: , mismatch: 1, identity: 0.952

tctccgccattgccgcccgct	CRISPR spacer
tcgccgccattgccgcccgct	Protospacer
** ******************

78. spacer 3.9|669569|21|NZ_CP018300|CRISPRCasFinder matches to NC_007766 (Rhizobium etli CFN 42 plasmid p42f, complete sequence) position: , mismatch: 1, identity: 0.952

gccccgctggggccggcgttg	CRISPR spacer
gcctcgctggggccggcgttg	Protospacer
***.*****************

79. spacer 3.9|669569|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 1, identity: 0.952

gccccgctggggccggcgttg	CRISPR spacer
gcctcgctggggccggcgttg	Protospacer
***.*****************

80. spacer 3.9|669569|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP020911 (Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence) position: , mismatch: 1, identity: 0.952

gccccgctggggccggcgttg	CRISPR spacer
gcctcgctggggccggcgttg	Protospacer
***.*****************

81. spacer 3.9|669569|21|NZ_CP018300|CRISPRCasFinder matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 1, identity: 0.952

gccccgctggggccggcgttg	CRISPR spacer
gcctcgctggggccggcgttg	Protospacer
***.*****************

82. spacer 3.9|669569|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 1, identity: 0.952

gccccgctggggccggcgttg	CRISPR spacer
gcctcgctggggccggcgttg	Protospacer
***.*****************

83. spacer 3.13|669764|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP015740 (Shinella sp. HZN7 plasmid pShin-04, complete sequence) position: , mismatch: 1, identity: 0.952

cggccgccctttccgccggcc	CRISPR spacer
cggccgccctttccggcggcc	Protospacer
*************** *****

84. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 1, identity: 0.955

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcggcc	Protospacer
*********************

85. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.955

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcggcc	Protospacer
*********************

86. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016457 (Sphingobium sp. RAC03 plasmid pBSY17_2, complete sequence) position: , mismatch: 1, identity: 0.955

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcgggccggcggca	Protospacer
**********.***********

87. spacer 8.15|1567543|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

88. spacer 8.15|1567543|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

89. spacer 8.15|1567543|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

90. spacer 8.15|1567543|22|NZ_CP018300|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 1, identity: 0.955

caatccggcggcgccgccggca	CRISPR spacer
caattcggcggcgccgccggca	Protospacer
****.*****************

91. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggag	Protospacer
*******************

92. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggca	Protospacer
*******************.

93. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
tggccgccggcgccgccggtc	Protospacer
. *******************

94. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP029209 (Nitratireductor sp. OM-1 plasmid pOM-1, complete sequence) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggcg	Protospacer
*******************.

95. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NC_016588 (Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggcg	Protospacer
*******************.

96. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MN234219 (Mycobacterium phage Mercurio, complete genome) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
gcgccgccggcgccgccggtg	Protospacer
 *******************

97. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to MK494105 (Mycobacterium phage Pinnie, complete genome) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
ccgccgccggcgccgccggcg	Protospacer
*******************.

98. spacer 2.2|668999|21|NZ_CP018300|CRISPRCasFinder matches to NZ_CP019037 (Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.905

ccgccgccggcgccgccggtc	CRISPR spacer
atgccgccggcgccgccggtc	Protospacer
 .*******************

99. spacer 8.2|1566617|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

100. spacer 8.2|1566617|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

101. spacer 8.2|1566617|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

102. spacer 8.2|1566617|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

103. spacer 8.2|1566617|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 2, identity: 0.909

gttgccgattaggacggcggcc	CRISPR spacer
cttgccgatcaggacggcggcc	Protospacer
 ********.************

104. spacer 8.3|1566671|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP025510 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvD, complete sequence) position: , mismatch: 2, identity: 0.909

ggtaccgtcctcgccggcggtg	CRISPR spacer
ggcaccgtcctcgccggcggtt	Protospacer
**.******************

105. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcc	Protospacer
.********************

106. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

107. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP021028 (Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

108. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013634 (Rhizobium sp. N324 plasmid pRspN324d, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcc	Protospacer
.********************

109. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013503 (Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

110. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013509 (Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

111. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013520 (Rhizobium sp. N113 plasmid pRspN113c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

112. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013493 (Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

113. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013516 (Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
atcgccgatcaggccggcggcg	Protospacer
.********************.

114. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcgggg	Protospacer
******************** .

115. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP012698 (Microbacterium sp. No. 7 plasmid A, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
accgccgatcaggccggcggca	Protospacer
..********************

116. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
ctcggcgatcaggccggcggca	Protospacer
 *** *****************

117. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatccggccggcggct	Protospacer
********** **********

118. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcc	Protospacer
***************** ***

119. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcc	Protospacer
***************** ***

120. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatccggccggcggct	Protospacer
********** **********

121. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcg	Protospacer
***************** ***.

122. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
ggcgccgatcaggccggcggcc	Protospacer
* *******************

123. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggcctgcggcg	Protospacer
*************** *****.

124. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatccggccggcggct	Protospacer
********** **********

125. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP024312 (Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcgccg	Protospacer
******************* *.

126. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgagcaggccggcggcc	Protospacer
******** ************

127. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.909

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccgggggcc	Protospacer
***************** ***

128. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.92

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacccgccgaacccgtcg	Protospacer
********** ******* ******

129. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.92

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacccgccgaacccgtcg	Protospacer
********** ******* ******

130. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.92

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacccgccgaacccgtcg	Protospacer
********** ******* ******

131. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgacctcggcggcgcgggcga	Protospacer
.***************** ****.

132. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
caccggcctgggcggcgctggcgg	Protospacer
 ****.*** **************

133. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP034768 (Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
taacgtcctcggcggcgctggcgg	Protospacer
 * ** ******************

134. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
agccgacctcggcggcgatggcgc	Protospacer
*.*************** *****

135. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_AP019631 (Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
taacgtcctcggcggcgctggcgg	Protospacer
 * ** ******************

136. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_AP019631 (Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
taacgtcctcggcggcgctggcgg	Protospacer
 * ** ******************

137. spacer 5.16|922753|24|NZ_CP018300|CRT matches to KU716094 (Mycobacterium phage Eidsmoe, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgcgctcggcggcgctggcgg	Protospacer
.****  *****************

138. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MH371122 (Mycobacterium phage Priya, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgcgctcggcggcgctggcgg	Protospacer
.****  *****************

139. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MK016502 (Mycobacterium phage Pat3, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
catcggcctcggcggcgctggcgg	Protospacer
 *.**.******************

140. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MK937593 (Mycobacterium phage Flypotenuse, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
catcggcctcggcggcgctggcgg	Protospacer
 *.**.******************

141. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MG872835 (Mycobacterium phage Conquerage, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgcgctcggcggcgctggcgg	Protospacer
.****  *****************

142. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MH536820 (Mycobacterium phage Glexan, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
catcggcctcggcggcgctggcgg	Protospacer
 *.**.******************

143. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
aaccggcctcggcggcgctgccgc	Protospacer
*****.************** **

144. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP013426 (Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
caccgagctcggcggcgctgccgg	Protospacer
 ***** ************* ***

145. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
caccggcctcggcggcgcgggcgg	Protospacer
 ****.************ *****

146. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MH271298 (Microbacterium phage Floof, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
aacccacctcggcggcgatggcgc	Protospacer
**** ************ *****

147. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_KY349138 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence) position: , mismatch: 3, identity: 0.864

gtcgccgatcaggccggcggca	CRISPR spacer
gtcgccgatcaggccggcgcgg	Protospacer
*******************  .

148. spacer 8.4|1566725|22|NZ_CP018300|CRISPRCasFinder matches to NZ_CP021649 (Acidovorax sp. T1 plasmid p1-T1, complete sequence) position: , mismatch: 3, identity: 0.864

gtcgccgatcaggccggcggca	CRISPR spacer
ttcgccgatcaggccggcggtg	Protospacer
 *******************..

149. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
ctcgccgaacacgcggaagccgtct	Protospacer
**.*********** *********

150. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
attgtcgaacacgcggaagccgtcg	Protospacer
 ***.********* **********

151. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to MN586053 (Arthrobacter phage BeatusComedenti, complete genome) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaactcgccgaagccgttg	Protospacer
 ********* ************.*

152. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NC_031254 (Arthrobacter phage Kitkat, complete genome) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaactcgccgaagccgttg	Protospacer
 ********* ************.*

153. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NC_031231 (Arthrobacter phage KellEzio, complete genome) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaactcgccgaagccgttg	Protospacer
 ********* ************.*

154. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
catgcggaacacgccgaatccgtcg	Protospacer
* *** ************ ******

155. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP030129 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.88

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgatcacgccgtagccgttg	Protospacer
******** ******* ******.*

156. spacer 8.15|1567543|22|NZ_CP018300|CRISPRCasFinder matches to NC_008270 (Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence) position: , mismatch: 3, identity: 0.864

caatccggcggcgccgccggca	CRISPR spacer
gaatccggcggcgccgccgggc	Protospacer
 *******************

157. spacer 10.9|2071782|24|NZ_CP018300|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 3, identity: 0.875

atcgaagaagctgaacccgccgtt	CRISPR spacer
cgcgaagaagctgaagccgccgtt	Protospacer
  ************* ********

158. spacer 10.9|2071782|24|NZ_CP018300|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 3, identity: 0.875

atcgaagaagctgaacccgccgtt	CRISPR spacer
cgcgaagaagctgaagccgccgtt	Protospacer
  ************* ********

159. spacer 1.1|365948|27|NZ_CP018300|CRISPRCasFinder matches to NC_023591 (Mycobacterium phage Adler, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

160. spacer 1.1|365948|27|NZ_CP018300|CRISPRCasFinder matches to KF981876 (UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

161. spacer 1.7|366344|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 4, identity: 0.852

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ccgaagccgatgtcgtagcggccggcg	Protospacer
 ************.***** *****.*

162. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgaaggtgaggtcgccgggg	Protospacer
.* ********* ***********.**

163. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NC_016652 (Rhodococcus phage REQ2, complete genome) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
acggcgccgaagttgaggccgccgacg	Protospacer
**  **************.****** *

164. spacer 5.10|922468|27|NZ_CP018300|CRT matches to KY945355 (Mycobacterium phage Shandong1, complete genome) position: , mismatch: 4, identity: 0.852

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgcatccggcggcggcggttgcgttct	Protospacer
** **************** ***** .

165. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_CP015095 (Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence) position: , mismatch: 4, identity: 0.852

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cggcctcggcggcggcggtggcgttgc	Protospacer
*** ..*************.*******

166. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NC_041888 (Mycobacterium phage Tortellini, complete genome) position: , mismatch: 4, identity: 0.852

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cggccgcggcggcggcggtagcggtgc	Protospacer
*** . ***************** ***

167. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 4, identity: 0.867

cctgctgttcggctccggcggcgctggcgg-	CRISPR spacer
gctgctgttcggcgccggcggcg-tggtggc	Protospacer
 ************ ********* ***.**

168. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ctacgaccacggcggcgctggcgg	Protospacer
   ***** ***************

169. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP025431 (Paracoccus zhejiangensis strain J6 plasmid pPZ01, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
gcccgatctcggcggcgctggcgt	Protospacer
. ****.****************

170. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tcccgacctcggcggtgctggcgc	Protospacer
  *************.*******

171. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP016822 (Rhodococcus sp. p52 plasmid pDF03, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
cgtcgacgtcggcggcgctggcgg	Protospacer
 ..**** ****************

172. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MN582086 (Siphoviridae sp. ctdEk19, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
cttcgacttcggcggcgctggcgg	Protospacer
  .****.****************

173. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MF919502 (Mycobacterium phage Demsculpinboyz, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

174. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MT889380 (Mycobacterium phage Coco12, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

175. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NC_023698 (Mycobacterium phage Avani, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

176. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MT114167 (Mycobacterium phage Phanphagia, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

177. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
cgccgacctcggcggcggtggcga	Protospacer
 .*************** *****.

178. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tcccgacctcggcggtgctggcgc	Protospacer
  *************.*******

179. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ctacgaccacggcggcgctggcgg	Protospacer
   ***** ***************

180. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tctcgacctcggcggcgatggcgg	Protospacer
  .************** ******

181. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MN096355 (Mycobacterium phage Purky, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tgccgacctcggctgcgctggcgc	Protospacer
 .*********** *********

182. spacer 5.16|922753|24|NZ_CP018300|CRT matches to MK279853 (Gordonia phage Gray, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ggtcgacctcgacggcgctggcgg	Protospacer
...********.************

183. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 4, identity: 0.857

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gccgccgggggtgccctcgttgccgggc	Protospacer
*..************ ********** *

184. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 4, identity: 0.857

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gccgccgggggtgccctcgttgccgggc	Protospacer
*..************ ********** *

185. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 4, identity: 0.857

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gccgccgggggtgccctcgttgccgggc	Protospacer
*..************ ********** *

186. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP021372 (Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
tccgccgaacgcgccgaagccgtcg	Protospacer
...*******.**************

187. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to LR134127 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gctgccgaacacgccgatgccgacg	Protospacer
 .*************** **** **

188. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to LR134127 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 7) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gctgccgaacacgccgatgccgacg	Protospacer
 .*************** **** **

189. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to MT553342 (Microbacterium phage Kelcole, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gatgctgatcacgccgaagccgtcg	Protospacer
  ***.** ****************

190. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NC_048068 (Microbacterium phage OneinaGillian, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gatgctgatcacgccgaagccgtcg	Protospacer
  ***.** ****************

191. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to MT310894 (Microbacterium phage Tempo, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gatgctgatcacgccgaagccgtcg	Protospacer
  ***.** ****************

192. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP047175 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cttgccgaacacgccgatgccctgc	Protospacer
***************** *** *

193. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
aatgccgaattcgccgaagccgtcg	Protospacer
  *******. **************

194. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to MN034284 (Leviviridae sp. isolate H2_Rhizo_Litter_49_scaffold_25938 sequence) position: , mismatch: 4, identity: 0.84

cttgccgaacacgccgaagccgtcg	CRISPR spacer
cccgtagaacacgccgaagccgtcg	Protospacer
*..*. *******************

195. spacer 8.14|1567486|25|NZ_CP018300|CRISPRCasFinder matches to MN582064 (Podoviridae sp. ctka020, complete genome) position: , mismatch: 4, identity: 0.84

cttgccgccaccgacccccccttgc	CRISPR spacer
ttttccgacaccgacccccccttga	Protospacer
.** *** ****************

196. spacer 10.9|2071782|24|NZ_CP018300|CRT matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
atcgaagaagctgaacacgcccgc	Protospacer
**************** ****  .

197. spacer 10.9|2071782|24|NZ_CP018300|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
gtcgatgaagctgaacccgccgaa	Protospacer
.**** ****************

198. spacer 10.9|2071782|24|NZ_CP018300|CRT matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
atcggagaagctgaacccgcccgg	Protospacer
****.****************

199. spacer 1.1|365948|27|NZ_CP018300|CRISPRCasFinder matches to LR794124 (Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .*

200. spacer 1.1|365948|27|NZ_CP018300|CRISPRCasFinder matches to NC_012662 (Vibrio phage VP93, complete genome) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .*

201. spacer 1.7|366344|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
gcgaagccgaagttgtagctgcgctcg	Protospacer
********** ***********   .*

202. spacer 1.7|366344|27|NZ_CP018300|CRISPRCasFinder matches to MN693945 (Marine virus AFVG_250M952, complete genome) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
atgaagccgatgttgtcgctaccgggg	Protospacer
..************** ***.**** *

203. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

204. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

205. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

206. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP015368 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccccgcggaagttgaggtcgcgggtg	Protospacer
 ****** ************** *. *

207. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

208. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

209. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

210. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

211. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

212. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

213. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

214. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

215. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP020444 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ******

216. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

217. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

218. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* *******

219. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP044078 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ******

220. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP031081 (Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ******

221. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MN586031 (Gordonia phage Gambino, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

222. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to KU998236 (Gordonia phage Blueberry, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

223. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MN062704 (Gordonia phage JuJu, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

224. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MK501729 (Gordonia phage Walrus, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

225. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NC_031226 (Gordonia phage BaxterFox, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

226. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MK967393 (Rhodococcus phage Whack, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccttaccgaagttgaggtcgacgagg	Protospacer
 **...*************** *****

227. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MT723935 (Gordonia phage Azula, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

228. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to KU963249 (Gordonia phage Yeezy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

229. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MH153808 (Gordonia phage Petra, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

230. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MT639650 (Gordonia phage Ohgeesy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

231. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MH536818 (Gordonia phage Frokostdame, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

232. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to KX557275 (Gordonia phage CarolAnn, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

233. spacer 5.5|922258|27|NZ_CP018300|CRT matches to KX683875 (Mycobacterium phage Baehexic, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

234. spacer 5.5|922258|27|NZ_CP018300|CRT matches to KM197169 (Mycobacterium phage Piro94, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

235. spacer 5.5|922258|27|NZ_CP018300|CRT matches to MF668269 (Mycobacterium phage Drake55, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

236. spacer 5.5|922258|27|NZ_CP018300|CRT matches to MK284522 (Mycobacterium phage Malec, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

237. spacer 5.5|922258|27|NZ_CP018300|CRT matches to KM677210 (Mycobacterium phage Larenn, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

238. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_CP022264 (Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
ggcaggcggcggcggcggtagcgttgg	Protospacer
 * *  ********************

239. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_CP022264 (Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
ggcaggcggcggcggcggtagcgttgg	Protospacer
 * *  ********************

240. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
aggatccggccgcggcggtagcgctcg	Protospacer
 ********* ************.*

241. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
aggatccggccgcggcggtagcgctcg	Protospacer
 ********* ************.*

242. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgggtccggcggcggcggtggcggttt	Protospacer
***.***************.*** * .

243. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_CP049908 (Hymenobacter sp. HDW8 plasmid p_unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgactccggcggcgggggtagcgttcg	Protospacer
**. *********** *********

244. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_CP049700 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgccgccggcggcggcggtggcgttgg	Protospacer
**   **************.******

245. spacer 5.10|922468|27|NZ_CP018300|CRT matches to MH576962 (Streptomyces phage Satis, complete genome) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
tgactccggcggcggccgtggcgttgc	Protospacer
.*. ************ **.*******

246. spacer 5.10|922468|27|NZ_CP018300|CRT matches to MK620894 (Streptomyces phage Kradal, complete genome) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
tgactccggcggcggccgtggcgttgc	Protospacer
.*. ************ **.*******

247. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgaggccggcctgctggtcgtctccgggct	Protospacer
*** **************** ******

248. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
agattccggcctgttcgtcggctccggcgg	Protospacer
 **. ********.* **************

249. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgccatcggcctgctgctcggcaccggcgg	Protospacer
** *..********** ***** *******

250. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP031193 (Humibacter sp. BT305 plasmid unnamed1) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgccgccggcctgctggtcggcgcggcggg	Protospacer
** ******************* * *  **

251. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP050092 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggc-tccggcgg	CRISPR spacer
cgacgccggcatgccggtcggcttcctgct-	Protospacer
********** ***.******* *** **

252. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
attgctgttcggctgcggcggcgcgggcgc	Protospacer
 .************ ********* ****

253. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
attgctgttcggctgcggcggcgcgggcgc	Protospacer
 .************ ********* ****

254. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcactcgg	Protospacer
*******.***** **********   ***

255. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctg--ttcggctccggcggcgctggcgg	CRISPR spacer
--tactgattacggctccggcggtgctggcgg	Protospacer
  *.***  * ************.********

256. spacer 5.15|922705|30|NZ_CP018300|CRT matches to AY950802 (Haloarcula phage SH1, complete genome) position: , mismatch: 5, identity: 0.833

--cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ggcctac--ttcggctccggcggctccggcgg	Protospacer
  ***.*  *************** *.*****

257. spacer 5.16|922753|24|NZ_CP018300|CRT matches to NC_006911 (Streptomyces sp. F11 plasmid pFP11, complete sequence) position: , mismatch: 5, identity: 0.792

aaccgacctcggcggcgctggcgg	CRISPR spacer
gggcgacctcggcggcgctggcct	Protospacer
.. *******************

258. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NZ_LN907828 (Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gctgccgtgggtgccatcgttgccgagt	Protospacer
*.***** *****************. .

259. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to KU728633 (Mycobacterium phage Bipper, complete genome) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gcgtccgggggtgccgtcgttgccgtcc	Protospacer
*.  ***********.********* **

260. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to MK977701 (Mycobacterium phage Cracklewink, complete genome) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gcgtccgggggtgccgtcgttgccgtcc	Protospacer
*.  ***********.********* **

261. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016354 (Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence) position: , mismatch: 5, identity: 0.821

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
gttgccgcgggtgccctcgttgcggacg	Protospacer
******* ******* ******* *.*

262. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP025013 (Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence) position: , mismatch: 5, identity: 0.8

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gccgccgaacacgccgaagccgttt	Protospacer
 ..********************.

263. spacer 8.5|1566779|25|NZ_CP018300|CRISPRCasFinder matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 5, identity: 0.8

cttgccgaacacgccgaagccgtcg	CRISPR spacer
gttgccgaacacgccgacgccgcgc	Protospacer
 **************** ****.

264. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NC_018746 (Pseudomonas putida ND6 plasmid pND6-2, complete sequence) position: , mismatch: 5, identity: 0.839

aattg--cgccttgcccgccgttgccgccggca	CRISPR spacer
--ttggccaccttgcacgcccttgccgccggca	Protospacer
  ***  *.****** **** ************

265. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to MN961671 (Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence) position: , mismatch: 5, identity: 0.839

aattg--cgccttgcccgccgttgccgccggca	CRISPR spacer
--ttggccaccttgcacgcccttgccgccggca	Protospacer
  ***  *.****** **** ************

266. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to MN961672 (Pseudomonas aeruginosa strain PA15W plasmid pPA15W-NR, complete sequence) position: , mismatch: 5, identity: 0.839

aattg--cgccttgcccgccgttgccgccggca	CRISPR spacer
--ttggccaccttgcacgcccttgccgccggca	Protospacer
  ***  *.****** **** ************

267. spacer 8.13|1567420|34|NZ_CP018300|CRISPRCasFinder matches to NC_006362 (Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence) position: , mismatch: 5, identity: 0.853

gtcgccgtgcagccagccaccaccgcca-ccggcg	CRISPR spacer
ttcgccgtgcagccggccaccacctccagcctgc-	Protospacer
 *************.********* *** ** **

268. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NC_010850 (Rhodococcus sp. NS1 plasmid pNSL1, complete sequence) position: , mismatch: 5, identity: 0.839

aacgccc-acttcaccgccgttgccgccgtca	CRISPR spacer
-acacccgacttcaccgccgctgccgccgaga	Protospacer
 **.*** ************.********  *

269. spacer 1.1|365948|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP045917 (Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence) position: , mismatch: 6, identity: 0.778

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
agttcactggtgtccacatcgcccgaa	Protospacer
*.. ***.***************** .

270. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agcaggtcgatcacgatctggccgttgccggcg	Protospacer
**   *.***** ******************.*

271. spacer 1.7|366344|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 6, identity: 0.778

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ggataggcgatgttgtagctgccggaa	Protospacer
* . ** ****************** .

272. spacer 1.9|366494|27|NZ_CP018300|CRISPRCasFinder matches to NC_009959 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence) position: , mismatch: 6, identity: 0.778

gccaagccgatatcgaagatcccggtg	CRISPR spacer
accatgccgatatcgacgatcccgtcc	Protospacer
.*** *********** ******* .

273. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tagacgccgaagtcgaggtcggcgagg	Protospacer
    *********.******* *****

274. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
ctcccgccgaagttgagggtgccgaac	Protospacer
 .**************** .*****.

275. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
aagaagccgaagttgaggtcgccgtag	Protospacer
*    ******************* .*

276. spacer 1.10|366554|27|NZ_CP018300|CRISPRCasFinder matches to MK494099 (Mycobacterium phage Typha, complete genome) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
cggtcgccgaggtcgaggtcgccgagg	Protospacer
   .******.**.*************

277. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to GQ141189 (Bifidobacterium phage Bbif-1, complete sequence) position: , mismatch: 6, identity: 0.806

agcgcgaacggcaagccgaac----cgttggaccc	CRISPR spacer
agcgcgaacggccagccgaaccatgcgctgg----	Protospacer
************ ********    **.***

278. spacer 5.5|922258|27|NZ_CP018300|CRT matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
gatggccggtaggctgttgaacggcgc	Protospacer
.. *******.******* *******

279. spacer 5.5|922258|27|NZ_CP018300|CRT matches to NC_023606 (Mycobacterium phage CRB1, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

280. spacer 5.5|922258|27|NZ_CP018300|CRT matches to MK524491 (Mycobacterium phage Whabigail7, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

281. spacer 5.5|922258|27|NZ_CP018300|CRT matches to KX619650 (Mycobacterium phage Jerm, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

282. spacer 5.5|922258|27|NZ_CP018300|CRT matches to MN585998 (Mycobacterium phage Bugsy, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

283. spacer 5.5|922258|27|NZ_CP018300|CRT matches to JN408460 (Mycobacterium phage Turbido, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

284. spacer 5.5|922258|27|NZ_CP018300|CRT matches to MH077576 (Mycobacterium phage AbbyPaige, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

285. spacer 5.5|922258|27|NZ_CP018300|CRT matches to MH825704 (Mycobacterium phage LilTurb, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

286. spacer 5.10|922468|27|NZ_CP018300|CRT matches to NZ_AP021845 (Azospira sp. I09 plasmid pAZI09, complete sequence) position: , mismatch: 6, identity: 0.778

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cggatcctgcggcggcggtagaaagcc	Protospacer
******* ************* .   *

287. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gagcgtcggcctgctggtcggcttcggcgc	Protospacer
 ..**.*****************.*****

288. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gagcgtcggcctgctggtcggcttcggcgc	Protospacer
 ..**.*****************.*****

289. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgacggcctggtggtcggctacctcga	Protospacer
***** ******* ********* *  **.

290. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP050083 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgatcggcctgctgctcggcaccggcgg	Protospacer
**  ..********** ***** *******

291. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP049733 (Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgatcggcctgctgctcggcaccggcgg	Protospacer
**  ..********** ***** *******

292. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgcgcggcgtgccggtcggctccggcgg	Protospacer
**    **** ***.***************

293. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgatcggcctgctgctcggcaccggcgg	Protospacer
**  ..********** ***** *******

294. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgcgcggcgtgccggtcggctccggcgg	Protospacer
**    **** ***.***************

295. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcggcgggcctgctggtcggcttcggcac	Protospacer
**  ** ****************.****.

296. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

297. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

298. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

299. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP037868 (Hydrogenophaga pseudoflava strain DSM 1084 plasmid pDSM1084, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcg----gctccggcgg	CRISPR spacer
cgacgccggccggctggtcggagagctgcg----	Protospacer
*********** ********    *** **

300. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

301. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

302. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgtcgccggcctgctgatcggcttcttctg	Protospacer
** *************.******.*  * *

303. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

304. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

305. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

306. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

307. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

308. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

309. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

310. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

311. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_019408 (Caulobacter phage CcrRogue, complete genome) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgtcatcggcctgctggtcgtcgccggcgc	Protospacer
** *..************** * ******

312. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgccgacctgctggtcggggcggactg	Protospacer
********.************  * *.* *

313. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP017941 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
caagctggtcggccccggcggcgctggcaa	Protospacer
*  **** *****.**************..

314. spacer 5.15|922705|30|NZ_CP018300|CRT matches to MK937608 (Microbacterium phage Cressida, complete genome) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tcacctgtccggctccggcggcggtggcga	Protospacer
.*  ****.************** *****.

315. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP050083 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcgcttgg	Protospacer
*******.***** **********   .**

316. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP049733 (Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcgcttgg	Protospacer
*******.***** **********   .**

317. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP017592 (Pantoea stewartii subsp. stewartii DC283 plasmid ppDSJ01, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg--	CRISPR spacer
tctgctgttcggctgcggcggcg--agcagcg	Protospacer
.************* ********  .**.*

318. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP008898 (Enterobacter hormaechei subsp. hoffmannii ECNIH3 plasmid pENT-576, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

319. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP023489 (Klebsiella pneumoniae subsp. pneumoniae strain ST101:960186733 plasmid p19-10_02, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

320. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP043515 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

321. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcgcttgg	Protospacer
*******.***** **********   .**

322. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_LT984809 (Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
catcgcgctcggcttcggcggcgctggcgg	Protospacer
* *  .*.******.***************

323. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP026371 (Klebsiella quasipneumoniae strain A708 plasmid pA708-3, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

324. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP050069 (Klebsiella aerogenes strain 035 plasmid p035_A-VIM-1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

325. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP039425 (Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgttcggcaccgacggcgccctccg	Protospacer
************* ***.******.  * *

326. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP009856 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-784, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

327. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP039430 (Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgttcggcaccgacggcgccctccg	Protospacer
************* ***.******.  * *

328. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP040937 (Hymenobacter sp. DG01 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgt-tcggctccggcggcgctggcgg	CRISPR spacer
-ccgccgcgccggctccggccgcgctggcgg	Protospacer
 *.**.*. .********** **********

329. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cgtccagctcggcgccggcggcgctggcgt	Protospacer
* * * *.***** ***************

330. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cgtccagctcggcgccggcggcgctggcgt	Protospacer
* * * *.***** ***************

331. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP006588 (Hymenobacter sp. APR13 plasmid pHA, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgt-tcggctccggcggcgctggcgg	CRISPR spacer
-ccgccgcgccggctccggccgcgctggcgg	Protospacer
 *.**.*. .********** **********

332. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgtt--cggctccggcggcgctggcgg	CRISPR spacer
--cgccgctggcggcgccggcggcgctggcgg	Protospacer
  .**.*.*  **** ****************

333. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgtt----cggctccggcggcgctggcgg	CRISPR spacer
----cagttggggcggctccggcggcgcgggcgg	Protospacer
    * ***    *************** *****

334. spacer 5.15|922705|30|NZ_CP018300|CRT matches to MH029534 (Myoviridae environmental samples clone NHS-Seq2, complete sequence) position: , mismatch: 6, identity: 0.8

-cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
atttggt-ttcggcgctggcggcgctggcgg	Protospacer
 ..** * ****** *.**************

335. spacer 5.17|922795|36|NZ_CP018300|CRT matches to MT723940 (Mycobacterium phage Ellie, complete genome) position: , mismatch: 6, identity: 0.833

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
cgttgtcggcaacggcggtaacggcgggggtggcgg	Protospacer
  * .************************ .*****

336. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NZ_AP022571 (Mycolicibacterium poriferae strain JCM 12603 plasmid pJCM12603, complete sequence) position: , mismatch: 6, identity: 0.786

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
ggtgccgggggtggcaccgttgccgcgg	Protospacer
* *********** **.********

337. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NC_008703 (Mycobacterium sp. KMS plasmid pMKMS01, complete sequence) position: , mismatch: 6, identity: 0.786

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
ggtgccgggggtggcaccgttgccgcgg	Protospacer
* *********** **.********

338. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NZ_LR594663 (Variovorax sp. RA8 plasmid 2) position: , mismatch: 6, identity: 0.786

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
ggtgccggcggtgccatcggtgccgagg	Protospacer
* ****** ********** *****.

339. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 6, identity: 0.806

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ccttgcgccttgcccgccgctgccgcagggc	Protospacer
  *****************.****** **

340. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 6, identity: 0.806

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ccttgcgccttgcccgccgctgccgcagggc	Protospacer
  *****************.****** **

341. spacer 8.13|1567420|34|NZ_CP018300|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 6, identity: 0.824

--gtcgccgtgcagccagccaccaccgccaccggcg	CRISPR spacer
ctgtcgtc--gcagcgcgccaccaccgccaccggca	Protospacer
  ****.*  *****  ******************.

342. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NC_009478 (Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence) position: , mismatch: 6, identity: 0.806

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgaccacttcaccgccgtcgccgccggcg	Protospacer
. ** ***************.******* *.

343. spacer 1.4|366143|27|NZ_CP018300|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.741

aagccgcccgagttcgcgagaccgaag	CRISPR spacer
tgaccgcccgagttcgcgagacgttgg	Protospacer
 ..*******************   .*

344. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MK977708 (Mycobacterium phage Fulbright, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

345. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MG099948 (Mycobacterium phage Philonius, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

346. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MH926055 (Mycobacterium phage Chewbacca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

347. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MT723932 (Mycobacterium phage Schnauzer, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

348. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to KU935726 (Mycobacterium phage Xerxes, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

349. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to KU935730 (Mycobacterium phage Pipsqueaks, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

350. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MH316570 (Mycobacterium phage Silvafighter, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

351. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MK524518 (Mycobacterium phage Smurph, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

352. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MK524515 (Mycobacterium phage Parmesanjohn, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

353. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MH697585 (Mycobacterium phage Gex, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

354. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to KM588359 (Mycobacterium phage Carcharodon, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

355. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MH697576 (Mycobacterium phage Aggie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

356. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MH697593 (Mycobacterium phage Tapioca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

357. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to MG099936 (Mycobacterium phage Andies, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

358. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to NC_031243 (Mycobacterium phage Xeno, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

359. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to JN256079 (Mycobacterium phage Charlie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *

360. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggtcgccggcctgctggtcgggttcggatc	Protospacer
 * ****************** *.***

361. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

362. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

363. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ctgctgcagcctgctggtcagctccggcgc	Protospacer
* .*  *.***********.*********

364. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

365. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

366. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ctgctgcagcctgctggtcagctccggcgc	Protospacer
* .*  *.***********.*********

367. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

368. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

369. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

370. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

371. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

372. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

373. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgggaccggcccgctggtcggccccggctt	Protospacer
**. .******.**********.*****

374. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gctgggcggcctgctggtcggctggggcgg	Protospacer
    * *****************  *****

375. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

376. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

377. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

378. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

379. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

380. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

381. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgcaggtcggcttcacctt	Protospacer
 ************* ********.*. *

382. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

383. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

384. spacer 5.13|922609|30|NZ_CP018300|CRT matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

385. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

386. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

387. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

388. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

389. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

390. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

391. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

392. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

393. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

394. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

395. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

396. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

397. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

398. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

399. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

400. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

401. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

402. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

403. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

404. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

405. spacer 5.13|922609|30|NZ_CP018300|CRT matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

406. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

407. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

408. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

409. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

410. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

411. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

412. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

413. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

414. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

415. spacer 5.13|922609|30|NZ_CP018300|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

416. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

417. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

418. spacer 5.13|922609|30|NZ_CP018300|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

419. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

420. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

421. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

422. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

423. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

424. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

425. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

426. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

427. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

428. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

429. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

430. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

431. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

432. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

433. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

434. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

435. spacer 5.13|922609|30|NZ_CP018300|CRT matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

436. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

437. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

438. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

439. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

440. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

441. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

442. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

443. spacer 5.13|922609|30|NZ_CP018300|CRT matches to HM560026 (Uncultured bacterium plasmid pTRACA45, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
acacgccgccctgctggtcggcttaggtcg	Protospacer
  ****** **************. **. *

444. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_010867 (Neisseria lactamica plasmid pNL3.1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gaacgccgccctgctggtcggcttagtcgc	Protospacer
 .****** **************. * **

445. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
agacgccggcctgctgttcggcctcgaccc	Protospacer
 *************** *****..**.*

446. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgggctcggcctgctgctcggcttcggcga	Protospacer
**.  .********** ******.*****.

447. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggc-tccggcgg	CRISPR spacer
gtcggccggcctgctggtcggcgcccggct-	Protospacer
    ****************** .*****

448. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgacggcctgctggtcgacttcatccc	Protospacer
***** **************.**.*. *

449. spacer 5.13|922609|30|NZ_CP018300|CRT matches to KT997827 (Uncultured Mediterranean phage uvDeep-CGR0-KM15-C219, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gttcgccggcctgctggaccgctccgtggg	Protospacer
   ************** * ******  **

450. spacer 5.13|922609|30|NZ_CP018300|CRT matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgtgtccggcctgctggtcgggttcggcac	Protospacer
**   **************** *.****.

451. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
tgacgccgccctgctggtcggcaaagtcga	Protospacer
.******* *************   * **.

452. spacer 5.13|922609|30|NZ_CP018300|CRT matches to KT997829 (Uncultured Mediterranean phage uvDeep-CGR0-KM22-C158, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gttcgccggcctgctggaccgctccgtggg	Protospacer
   ************** * ******  **

453. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013634 (Rhizobium sp. N324 plasmid pRspN324d, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttcggggtcggctccggcggcgctggcga	Protospacer
..*   * *********************.

454. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP035001 (Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttcggggtcggctccggcggcgctggcga	Protospacer
..*   * *********************.

455. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctccgcgctcggctccggcggcggtggcgg	Protospacer
*..  .*.*************** ******

456. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

457. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

458. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP020909 (Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

459. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.***************

460. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP020951 (Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

461. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NC_021908 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

462. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP020441 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.***************

463. spacer 5.15|922705|30|NZ_CP018300|CRT matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

464. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP044080 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.***************

465. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

466. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

467. spacer 5.15|922705|30|NZ_CP018300|CRT matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg-	CRISPR spacer
actgctgtccggctccggcggca-tgatgtc	Protospacer
 *******.*************. **..*

468. spacer 5.15|922705|30|NZ_CP018300|CRT matches to MN582086 (Siphoviridae sp. ctdEk19, complete genome) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gccggccttcgacttcggcggcgctggcgg	Protospacer
 *.* . ****.**.***************

469. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

470. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP022700 (Acetobacter tropicalis strain BDGP1 plasmid pAtBDGP1A, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gttcctccacggttccggcggcgctggcgg	Protospacer
 .* ** . ***.*****************

471. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

472. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

473. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

474. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP031082 (Paracoccus yeei strain CCUG 32053 plasmid pYEE4, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.***************

475. spacer 5.17|922795|36|NZ_CP018300|CRT matches to NC_022087 (Mycobacterium phage AnnaL29, complete genome) position: , mismatch: 7, identity: 0.806

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
cgtgatcggcaacggcggaaacggcgggagctgggg	Protospacer
  **************** *********. * * **

476. spacer 8.1|1566557|28|NZ_CP018300|CRISPRCasFinder matches to NC_010553 (Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence) position: , mismatch: 7, identity: 0.75

gttgccgggggtgccatcgttgccggcc	CRISPR spacer
agcacccggggtgccgtcgttgccggcg	Protospacer
. ..** ********.***********

477. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP041045 (Paracoccus sp. AK26 plasmid pAK1, complete sequence) position: , mismatch: 7, identity: 0.774

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gttgccgccatgcccgccgctgccgccggcc	Protospacer
. *  **** *********.**********

478. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to CP017041 (Propionibacterium sp. oral taxon 193 strain F0672 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
aacggcgtcttgcccgccgtggccgccaccg	Protospacer
**. ***.************ ******. *.

479. spacer 10.7|2071692|30|NZ_CP018300|CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

480. spacer 10.7|2071692|30|NZ_CP018300|CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

481. spacer 10.7|2071692|30|NZ_CP018300|CRT matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

482. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

483. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

484. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP042263 (Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atccgccatttcaccgccgttgccgacgccg	Protospacer
* *  ***.**************** **.*.

485. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttggtgtcgatctcgatctggccgttgcccgca	Protospacer
  * **.*****.**************** *..

486. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.*******

487. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
atgctgccgaccccgatctggtcgttttcgact	Protospacer
* ********.**********.**** .**..

488. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtcgaccttc	Protospacer
 ***************** ** ***.* *  *

489. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.*******

490. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgccggcctgctggtcgggctgacctc	Protospacer
********************* .. . *

491. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ccgcaaactcctgctggtcggcgccggcgg	Protospacer
* .*.    ************* *******

492. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgatgccggcctgctggtcggggttcccag	Protospacer
***.*****************  ..  *.*

493. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ccgcaaactcctgctggtcggcgccggcgg	Protospacer
* .*.    ************* *******

494. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ccttcagggcgtgctggtcggctccggcgc	Protospacer
*  .   *** ******************

495. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_KY126370 (Enterobacter cloacae subsp. cloacae strain MN201516 plasmid pOP-I, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

496. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP054625 (Cupriavidus gilardii strain FDAARGOS_639 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggccgccggcctgctgtgcggctccgcgct	Protospacer
 * *************  ********

497. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgatgccggcctgctggtcggggttcccag	Protospacer
***.*****************  ..  *.*

498. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_LT960615 (Hartmannibacter diazotrophicus strain E19T plasmid HDIAp1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gttcaccgccctgctgatcggctccggcat	Protospacer
   *.*** *******.***********.

499. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP046347 (Citrobacter portucalensis strain FDAARGOS_738 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

500. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP044100 (Citrobacter werkmanii strain FDAARGOS_616 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

501. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP032156 (Mycobacterium sp. ELW1 plasmid pELW1-1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
aatcgccggcctgctggtcggtgccgcggt	Protospacer
 . ******************. ***  *

502. spacer 5.13|922609|30|NZ_CP018300|CRT matches to KY555144 (Caulobacter phage Ccr5, complete genome) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggtgatcggcctgctggtcgtcgccggcgc	Protospacer
 *  ..************** * ******

503. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_KP873172 (Pseudomonas aeruginosa PAO1 plasmid pAMBL1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

504. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP045203 (Citrobacter sp. NMI7904_11 plasmid pCTEL-2, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

505. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NC_021492 (Enterobacter sp. R4-368 plasmid pENT01, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

506. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP022156 (Escherichia coli strain ABWA45 plasmid pABWA45_2, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

507. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP024682 (Citrobacter freundii strain UMH14 plasmid pUMH14_2, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** .

508. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgatgccggcctgctggtcggggttcccag	Protospacer
***.*****************  ..  *.*

509. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cgaccatctcggctccgacggcgctggcgc	Protospacer
*   *  .*********.***********

510. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

511. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gccaccccgcggctccggaggcgctggcgg	Protospacer
 *..*. . ********* ***********

512. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcaccggcggcgctggcga	Protospacer
. *   *.***** ***************.

513. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcaccggcggcgctggcga	Protospacer
. *   *.***** ***************.

514. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

515. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

516. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

517. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

518. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

519. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

520. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

521. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

522. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcaccggcggcgctggcga	Protospacer
. *   *.***** ***************.

523. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgatcggctccggcgccggcttctc	Protospacer
******* ************ ** .  *

524. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgtgcggctccggcggcaaccccga	Protospacer
 ******* *************. .  **.

525. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_LR134452 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgatgttcgactccggcggcgacgcacc	Protospacer
**** ******.*********** .*

526. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gcaccgcgccggctccggcggcggtggcgg	Protospacer
 *  *   .************** ******

527. spacer 5.17|922795|36|NZ_CP018300|CRT matches to MG770216 (Mycobacterium phage Rem711, complete genome) position: , mismatch: 8, identity: 0.778

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
attcggcggcaacggcggcaacggcgcggccggcgc	Protospacer
..* . ************.******* ********

528. spacer 5.17|922795|36|NZ_CP018300|CRT matches to KY087993 (Mycobacterium phage Hammy, complete genome) position: , mismatch: 8, identity: 0.778

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gcagatcggcaccggcggtaacggcggcggtgcagc	Protospacer
** ******** *************** * .*  *

529. spacer 5.17|922795|36|NZ_CP018300|CRT matches to MF140406 (Mycobacterium phage DarthP, complete genome) position: , mismatch: 8, identity: 0.778

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gcagatcggcaccggcggtaacggcggcggtgcagc	Protospacer
** ******** *************** * .*  *

530. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gcgggcgccttgtccgccgctgccgccgggc	Protospacer
.   ********.******.*********

531. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP039899 (Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

532. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP039913 (Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

533. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP039890 (Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

534. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP018001 (Rhizobium sp. Y9 plasmid pY9, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

535. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NC_022536 (Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

536. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP053858 (Rhizobium pusense strain 76 plasmid pR76, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

537. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gcgagcgccttgcccgccgtggtcgccgccc	Protospacer
.   **************** *.***** *

538. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to CP036360 (Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcagcgcaatgcccgccgttgccgccgcaa	Protospacer
... ****  ******************  *

539. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

aattgc--gccttgcccgccgttgccgccggca	CRISPR spacer
--ccgctggccttgcccggggttgccgccgggg	Protospacer
  ..**  **********  *********** .

540. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 8, identity: 0.742

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
attgccgccctggccgccgttgccgccgatc	Protospacer
* *  ****.** ***************..

541. spacer 10.7|2071692|30|NZ_CP018300|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.733

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ccgcgagcagccgtcggtttgcgcgctgtc	Protospacer
.** ... **************.******.

542. spacer 10.7|2071692|30|NZ_CP018300|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.733

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ccgcgagcagccgtcggtttgcgcgctgtc	Protospacer
.** ... **************.******.

543. spacer 13.6|3106519|29|NZ_CP018300|PILER-CR matches to MK599315 (Pseudomonas phage PA1C, complete genome) position: , mismatch: 8, identity: 0.724

tccgcgaaattcactgcgcgttattcaag	CRISPR spacer
gacgcgaaatacactgcgctttattttca	Protospacer
  ******** ******** *****.  .

544. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to CP033373 (Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ttagcccacttcacggccgttgccgacgcgg	Protospacer
   *********** ********** **. .

545. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

546. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

547. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

548. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

549. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

550. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

551. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

552. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

553. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

554. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cgcaactccttcaccgccgctgccgccgtct	Protospacer
 .*. *. ***********.**********

555. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

556. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

557. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

558. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ctcggtggcttcgccgccgtcgccgccgtca	Protospacer
  ** . .****.*******.**********

559. spacer 14.7|3725324|31|NZ_CP018300|CRT matches to NC_014213 (Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atcgcccacttcaccggcgtttccgaccctt	Protospacer
* ************** **** *** * ..

560. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatcccgatctggccgtcgccggcc	Protospacer
  *.  .******************.*****.

561. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  *

562. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  *

563. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  *

564. spacer 3.12|669704|36|NZ_CP018300|CRISPRCasFinder matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 9, identity: 0.75

gcgccttggctgccggttgtgcccgccggcccggcc	CRISPR spacer
gccccttggctgccggttgtgcacgccatcgatttc	Protospacer
** ******************* ****. *    .*

565. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP014964 (Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
ggaacgaacggcaagccgaaatgttggtgga	Protospacer
.* .**************** .*****

566. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to NC_015974 (Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. *

567. spacer 4.1|688318|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP005085 (Sphingobium sp. TKS plasmid pTK1, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. *

568. spacer 5.13|922609|30|NZ_CP018300|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.7

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggcgccggcctgctggtcggactgctcac	Protospacer
**.****************** ..   *.

569. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NC_005241 (Cupriavidus necator H16 megaplasmid pHG1, complete sequence) position: , mismatch: 9, identity: 0.7

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gaccacgttcggctccggccgcgctcgcgt	Protospacer
  .  .************* ***** ***

570. spacer 5.15|922705|30|NZ_CP018300|CRT matches to NZ_CP039289 (Cupriavidus necator H16 plasmid pHG1, complete sequence) position: , mismatch: 9, identity: 0.7

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gaccacgttcggctccggccgcgctcgcgt	Protospacer
  .  .************* ***** ***

571. spacer 5.17|922795|36|NZ_CP018300|CRT matches to MF140398 (Mycobacterium phage Amohnition, complete genome) position: , mismatch: 9, identity: 0.75

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gcagatcggcaccggcggtaacggcggcggtacggc	Protospacer
** ******** *************** * ..  *

572. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcctcgccctgcccgccgttgccgcccacg	Protospacer
.... ****.***************** .*.

573. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
tggcccgccttgccctccattgccgccggac	Protospacer
 . . ********** **.**********

574. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NC_022049 (Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
atccttgccttgaccgccgttgccgccgctg	Protospacer
* .. .****** *************** ..

575. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to MN234199 (Mycobacterium phage Ekdilam, complete genome) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
accccagccctgcccgccgttgccgccgctc	Protospacer
* ..  ***.****************** .

576. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gcttgcgcctggcccgccgtagccggacacc	Protospacer
. ******** ********* ****   .*

577. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP015737 (Shinella sp. HZN7 plasmid pShin-01, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
accggcaccttgcccgccattgccgccatgt	Protospacer
* . **.***********.********.

578. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013740 (Streptomyces globisporus C-1027 plasmid pSGL1, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
cgggccgccttgtccgccgtggccgccgacc	Protospacer
 .   *******.******* *******.*

579. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 9, identity: 0.71

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
agcgtggccttggccgccgttgccggcggtc	Protospacer
*..   ****** ************ ***.

580. spacer 14.5|3725183|34|NZ_CP018300|CRT matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
attgagatccgcgacgatgggtgtggcgccggcg	Protospacer
.**    .********.**** ***********.

581. spacer 14.5|3725183|34|NZ_CP018300|CRT matches to MG812496 (Gordonia phage SallySpecial, complete genome) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gcgcaccaccgcggcggtgcgggtggcgccggcg	Protospacer
*. . *. *****.***** *************.

582. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****.

583. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****.

584. spacer 1.6|366278|33|NZ_CP018300|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****.

585. spacer 5.2|922105|39|NZ_CP018300|CRT matches to NZ_CP044080 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

cggcgcgggcggggccgtcacgggaaccggcgccaccgg	CRISPR spacer
cacgggggccggggccgccacgggaaccggcgccccgcc	Protospacer
*.  * ** ********.**************** *

586. spacer 5.17|922795|36|NZ_CP018300|CRT matches to MN369764 (Mycobacterium phage Rahalelujah, complete genome) position: , mismatch: 10, identity: 0.722

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
atctggaggcaacggcggtaacggcggggccagcac	Protospacer
... .  ************************.**.

587. spacer 5.17|922795|36|NZ_CP018300|CRT matches to NZ_CP025548 (Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.722

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gaccggcggcaacggcggaaacggcggcgccgcagc	Protospacer
* . . ************ ******** ****  *

588. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gggctcgcctcgcccgccgttcccgccgctc	Protospacer
.. . *****.********** ****** .

589. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ttcctcgccttccccgccgctgccgccgcgg	Protospacer
  .. ****** *******.********  .

590. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggccagaacttccccgctgttgccgccggca	Protospacer
..... . *** *****.*************

591. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
gggctcgcctcgcccgccgttcccgccgctc	Protospacer
.. . *****.********** ****** .

592. spacer 8.10|1567171|31|NZ_CP018300|CRISPRCasFinder matches to NZ_AP014581 (Burkholderia sp. RPE67 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.677

aattgcgccttgcccgccgttgccgccggca	CRISPR spacer
ggcgtggccttggccgccgttgccggcggtc	Protospacer
...   ****** ************ ***.

593. spacer 8.13|1567420|34|NZ_CP018300|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 10, identity: 0.706

gtcgccgtgcagccagccaccaccgccaccggcg	CRISPR spacer
ccgatgatgcagccggccaccaccgccaccagca	Protospacer
 . .. .*******.***************.**.

594. spacer 12.9|3104026|35|NZ_CP018300|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 10, identity: 0.714

acttgcgcgcacaacgcatccgccatccacggggc	CRISPR spacer
gtcaccgcgcacaacacattcgccatccacacggt	Protospacer
...  **********.***.**********. **.

595. spacer 13.18|3107396|34|NZ_CP018300|PILER-CR matches to NZ_AP022335 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence) position: , mismatch: 10, identity: 0.706

tagaaggcgatcactggaagcacggcgcttgcga	CRISPR spacer
ggcaaggcgatcagtggaagctcggcggcggcac	Protospacer
 . ********** ******* ***** . **.

596. spacer 13.34|3107392|34|NZ_CP018300|CRISPRCasFinder,CRT matches to NZ_AP022335 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence) position: , mismatch: 10, identity: 0.706

tagaaggcgatcactggaagcacggcgcttgcga	CRISPR spacer
ggcaaggcgatcagtggaagctcggcggcggcac	Protospacer
 . ********** ******* ***** . **.

597. spacer 14.5|3725183|34|NZ_CP018300|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cagcgcggccgcgtcggtgggggtggcgcccgcc	Protospacer
   . *  ***** **************** **

598. spacer 14.5|3725183|34|NZ_CP018300|CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.

599. spacer 14.5|3725183|34|NZ_CP018300|CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.

600. spacer 14.5|3725183|34|NZ_CP018300|CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.

601. spacer 14.9|3725456|37|NZ_CP018300|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.73

cttgccggcggtgccggcgaccgcggtgccgccggtg	CRISPR spacer
ggagacggcggtgccggagaccgcggtgtcgctgccc	Protospacer
   * ************ **********.***.* .

602. spacer 14.5|3725183|34|NZ_CP018300|CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 11, identity: 0.676

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cgcccccggcgtgacggtggaggtggcgccggcc	Protospacer
  ...*.  **.********.************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2926707 : 2964980

Mycobacterium_phage(30.0%)

integrase,capsid,terminase,protease,head,tRNA

attL 2955509:2955536|attR 2965133:2965160

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003413486.1\|2926707_2928786_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	2.5e-104	34.9
WP_003413487.1\|2928894_2929122_+	hypothetical protein	NA	NA	NA	NA
WP_009938541.1\|2929118_2930504_-	PE family protein	NA	NA	NA	NA
WP_003413569.1\|2930848_2931349_+	DUF1990 family protein	NA	NA	NA	NA
WP_003413574.1\|2931365_2931806_-	DoxX family membrane protein	NA	NA	NA	NA
WP_003901437.1\|2931952_2932630_+	transcriptional regulator	NA	NA	NA	NA
WP_003413583.1\|2932614_2932968_-	cupin domain-containing protein	NA	NA	NA	NA
WP_003413586.1\|2932980_2933406_-	hypothetical protein	NA	NA	NA	NA
WP_003413588.1\|2933402_2934077_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003413589.1\|2934154_2934976_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003413592.1\|2935111_2936005_+	universal stress protein	NA	NA	NA	NA
WP_003413594.1\|2936007_2936826_-	universal stress protein	NA	NA	NA	NA
WP_003899401.1\|2936840_2938022_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_003413598.1\|2938080_2938512_-	CBS domain-containing protein	A0A2I6B2H4	Macacine_betaherpesvirus	1.9e-75	100.0
WP_003899402.1\|2939025_2940267_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003899403.1\|2940576_2940939_+	hypothetical protein	NA	NA	NA	NA
WP_003413610.1\|2941285_2942410_+	hypothetical protein	NA	NA	NA	NA
WP_003413614.1\|2942411_2942951_+	hypothetical protein	NA	NA	NA	NA
WP_003413616.1\|2943090_2944389_+	RNA-splicing ligase RtcB	A2RQD0	Archaeal_BJ1_virus	3.8e-90	43.3
WP_003413619.1\|2944427_2944709_-	DUF1876 domain-containing protein	NA	NA	NA	NA
WP_003413625.1\|2944853_2945339_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_003902325.1\|2945365_2945623_-	hypothetical protein	NA	NA	NA	NA
WP_009938544.1\|2945623_2947960_-	PE family protein	NA	NA	NA	NA
WP_003899405.1\|2947988_2948231_+	hypothetical protein	NA	NA	NA	NA
WP_003899406.1\|2948231_2948909_+	membrane protein	NA	NA	NA	NA
WP_003413657.1\|2949924_2950371_+	anti-sigma factor antagonist	NA	NA	NA	NA
WP_003413663.1\|2950545_2950878_-	YnfA family protein	NA	NA	NA	NA
WP_003413665.1\|2950997_2951357_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003413675.1\|2951458_2951917_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_003899407.1\|2952052_2952433_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003413686.1\|2952429_2953926_+	ACR3 family arsenite efflux transporter	A0A2H4PQT9	Staphylococcus_phage	5.1e-14	39.7
WP_085972563.1\|2954115_2954352_+	antitoxin MazE family protein	NA	NA	NA	NA
WP_077365235.1\|2954424_2954598_+	hypothetical protein	NA	NA	NA	NA
2955509:2955536	attL	NA	NA	NA	NA
WP_003899409.1\|2955642_2956074_+	hypothetical protein	NA	NA	NA	NA
WP_003900538.1\|2956070_2957069_+\|integrase	tyrosine-type recombinase/integrase	A0A2D1G8E2	Mycobacterium_phage	7.4e-62	47.8
WP_003900539.1\|2957082_2957547_+	hypothetical protein	NA	NA	NA	NA
WP_003908028.1\|2957534_2957786_+	hypothetical protein	NA	NA	NA	NA
WP_003899411.1\|2957956_2959396_-\|capsid	phage major capsid protein	A0A1B3AYS4	Gordonia_phage	1.4e-66	40.6
WP_003899412.1\|2959403_2959937_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	3.1e-06	32.9
WP_003899413.1\|2960089_2960716_-\|terminase	phage terminase small subunit P27 family	V9H0V4	Actinophage	1.6e-17	47.2
WP_003899414.1\|2960747_2961071_-	type II toxin-antitoxin system toxin	NA	NA	NA	NA
WP_003899415.1\|2961150_2961396_-	antitoxin	NA	NA	NA	NA
WP_003899416.1\|2961392_2962820_-	DUF3631 domain-containing protein	NA	NA	NA	NA
WP_003899417.1\|2962821_2963214_-	DUF2742 domain-containing protein	NA	NA	NA	NA
WP_014585547.1\|2963210_2963471_-	helix-turn-helix domain-containing protein	A0A2P1CHK7	Mycobacterium_phage	1.9e-14	63.1
WP_003900543.1\|2963487_2963850_-	hypothetical protein	NA	NA	NA	NA
WP_003899420.1\|2963852_2964980_-\|integrase	site-specific integrase	A0A1X9SFC1	Mycobacterium_phage	1.5e-66	40.4
2965133:2965160	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018300

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection