CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018257	Acinetobacter baumannii strain AF-673 plasmid pAF-673, complete sequence	0 crisprs	DEDDh	0	0	2	0
NZ_CP018256	Acinetobacter baumannii strain AF-673 chromosome, complete genome	1 crisprs	cas3,DEDDh,WYL,csa3,RT	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2184 : 54946

Salmonella_phage(30.77%)

transposase,tail,terminase,portal

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000097415.1\|2184_2823_-	lysozyme	A0A075DXC6	Acinetobacter_phage	2.0e-68	65.0
WP_000138816.1\|2822_3215_-	hypothetical protein	A0A0P0I8L9	Acinetobacter_phage	9.7e-34	56.2
WP_001185526.1\|3338_3542_+	hypothetical protein	NA	NA	NA	NA
WP_000281052.1\|3674_3926_-	hypothetical protein	NA	NA	NA	NA
WP_001121317.1\|3935_4670_-	hypothetical protein	NA	NA	NA	NA
WP_001262280.1\|4683_4998_-	hypothetical protein	NA	NA	NA	NA
WP_000992032.1\|4998_16182_-\|tail	tail protein	A4JX16	Burkholderia_virus	7.6e-155	36.4
WP_000959558.1\|16205_16784_-\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	2.5e-25	35.6
WP_000567460.1\|16777_17527_-	C40 family peptidase	J9Q7R4	Salmonella_phage	7.8e-48	40.5
WP_000504046.1\|17523_18219_-\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	2.8e-60	48.0
WP_000394499.1\|18218_18545_-\|tail	phage tail protein	D6PGG4	uncultured_phage	9.0e-09	31.1
WP_000896671.1\|18617_24206_-\|tail	tail length tape measure protein	NA	NA	NA	NA
WP_000771531.1\|24560_24914_-	hypothetical protein	NA	NA	NA	NA
WP_000002670.1\|25008_25554_-	hypothetical protein	A0A2H4P707	Pseudomonas_phage	6.3e-39	52.2
WP_000101578.1\|25638_26136_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_001068664.1\|26135_26522_-	hypothetical protein	J9Q6D8	Salmonella_phage	1.6e-12	32.8
WP_000494965.1\|26518_26869_-	hypothetical protein	J9Q7F6	Salmonella_phage	2.5e-09	35.1
WP_002027131.1\|26855_27551_-	hypothetical protein	NA	NA	NA	NA
WP_001110365.1\|27552_28323_-	hypothetical protein	NA	NA	NA	NA
WP_000769019.1\|28329_28824_-	hypothetical protein	L7TKJ9	Rhizobium_phage	6.8e-08	28.7
WP_001130341.1\|28962_29865_-	hypothetical protein	A0A2H4P701	Pseudomonas_phage	6.9e-91	58.3
WP_001131896.1\|30000_30879_-	hypothetical protein	A0A2H4P6Z8	Pseudomonas_phage	7.3e-13	29.4
WP_000206083.1\|30922_32593_-\|portal	phage portal protein	J9Q7R1	Salmonella_phage	5.3e-145	51.7
WP_000764108.1\|32638_33883_-\|terminase	terminase	A0A2H4P6Z9	Pseudomonas_phage	1.3e-151	62.4
WP_000134192.1\|33892_34498_-	hypothetical protein	J9Q6D4	Salmonella_phage	4.0e-18	34.3
WP_000084570.1\|34650_35052_-	hypothetical protein	NA	NA	NA	NA
WP_002027127.1\|35163_35658_-	hypothetical protein	A0A0D4DBK8	Acinetobacter_phage	5.4e-05	33.9
WP_001175928.1\|35626_35950_-	hypothetical protein	NA	NA	NA	NA
WP_000416809.1\|35940_36894_-	hypothetical protein	A0A2H4P6X5	Pseudomonas_phage	4.6e-61	42.1
WP_000184979.1\|36932_37355_-	thioredoxin family protein	NA	NA	NA	NA
WP_000312034.1\|37351_38008_-	ATP-binding cassette domain-containing protein	L7TNS9	Rhizobium_phage	5.9e-60	54.8
WP_001292430.1\|38007_38658_-	ParB N-terminal domain-containing protein	L7TMF9	Rhizobium_phage	3.8e-35	41.9
WP_000131110.1\|38654_39257_-	hypothetical protein	NA	NA	NA	NA
WP_000110211.1\|39285_39924_-	ParB N-terminal domain-containing protein	L7TL04	Rhizobium_phage	1.0e-48	46.1
WP_000521251.1\|40002_41712_+	DEAD/DEAH box helicase	L7TNS5	Rhizobium_phage	3.4e-131	46.2
WP_000741665.1\|41837_42131_+	hypothetical protein	NA	NA	NA	NA
WP_000146944.1\|42194_42473_-	hypothetical protein	NA	NA	NA	NA
WP_000819256.1\|42507_43077_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_000993863.1\|43470_44271_-	hypothetical protein	NA	NA	NA	NA
WP_000960557.1\|44711_45137_-	hypothetical protein	NA	NA	NA	NA
WP_001121876.1\|45868_46075_-	hypothetical protein	NA	NA	NA	NA
WP_000881636.1\|47401_47737_+	hypothetical protein	NA	NA	NA	NA
WP_000906141.1\|47800_48019_+	hypothetical protein	NA	NA	NA	NA
WP_000172716.1\|48126_48468_+	hypothetical protein	NA	NA	NA	NA
WP_000401859.1\|48526_48775_+	hypothetical protein	A0A0M3LSW2	Mannheimia_phage	1.3e-07	44.8
WP_000075093.1\|48850_49573_-	hypothetical protein	J9Q7Y8	Salmonella_phage	4.2e-14	34.1
WP_000495140.1\|49588_49915_-	hypothetical protein	NA	NA	NA	NA
WP_000119273.1\|50148_50394_-	hypothetical protein	NA	NA	NA	NA
WP_001202407.1\|51817_52981_-	glutathione-dependent formaldehyde dehydrogenase	E3SJ82	Synechococcus_phage	2.2e-09	29.0
WP_085942965.1\|53782_54946_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	8.8e-131	79.2

DBSCAN-SWA_2

71022 : 97892

Pseudomonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000774949.1\|71022_71388_-	nucleoside triphosphate pyrophosphohydrolase family protein	A0A0S0NAG1	Pseudomonas_phage	2.8e-35	63.6
WP_002017378.1\|71380_71638_-	hypothetical protein	NA	NA	NA	NA
WP_000047654.1\|71668_71896_-	hypothetical protein	NA	NA	NA	NA
WP_001019929.1\|71895_72180_-	hypothetical protein	NA	NA	NA	NA
WP_001167538.1\|72183_73095_-	hypothetical protein	A0A0K2FHE7	Achromobacter_phage	7.7e-66	44.4
WP_023897602.1\|73107_74097_-	ribonucleotide-diphosphate reductase subunit beta	A0A2H4P762	Pseudomonas_phage	2.5e-54	38.4
WP_001103335.1\|74194_76567_-	ribonucleoside-diphosphate reductase subunit alpha	A0A2H4P767	Pseudomonas_phage	3.1e-207	50.7
WP_000030999.1\|76588_76969_-	hypothetical protein	NA	NA	NA	NA
WP_000692605.1\|77042_77645_-	hypothetical protein	J9Q7Z7	Salmonella_phage	1.1e-31	42.8
WP_000192217.1\|77776_78613_-	hypothetical protein	NA	NA	NA	NA
WP_000698012.1\|78705_80646_-	AAA family ATPase	L7TNH6	Rhizobium_phage	6.4e-118	42.8
WP_002017393.1\|80645_81761_-	metallophosphoesterase	A0A2H4P756	Pseudomonas_phage	1.3e-59	38.1
WP_000234226.1\|82103_82484_-	hypothetical protein	NA	NA	NA	NA
WP_000095727.1\|82483_82945_-	hypothetical protein	NA	NA	NA	NA
WP_000680035.1\|82941_83301_-	hypothetical protein	NA	NA	NA	NA
WP_000433629.1\|83388_85587_-	recombinase RecA	J9Q736	Salmonella_phage	3.6e-53	50.7
WP_000429229.1\|85589_86627_-	5'-3' exonuclease	J9Q7S6	Salmonella_phage	8.8e-50	36.6
WP_001099771.1\|86689_87550_-	hypothetical protein	A0A2H4P7I7	Pseudomonas_phage	1.9e-29	31.5
WP_000034357.1\|87692_88781_-	hypothetical protein	A0A2H4P749	Pseudomonas_phage	5.0e-11	35.3
WP_000695256.1\|88870_90136_-	hypothetical protein	A0A2H4P750	Pseudomonas_phage	5.9e-72	38.1
WP_000432853.1\|90132_90708_-	HNH endonuclease	A0A2D1GG92	Gordonia_phage	2.1e-24	44.4
WP_000931856.1\|90756_93114_-	DNA polymerase III subunit alpha	L7TNG6	Rhizobium_phage	4.3e-177	43.4
WP_000840050.1\|93159_93840_-	hypothetical protein	NA	NA	NA	NA
WP_000252084.1\|93890_94556_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_000063932.1\|94580_95825_-	AAA family ATPase	L7TKP0	Rhizobium_phage	2.4e-86	41.7
WP_001005716.1\|95969_97892_-	hypothetical protein	A0A2H4P735	Pseudomonas_phage	3.9e-75	43.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP018256

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018256_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018256_1

2344582-2344667

Orphan

Consensus_repeat	Method
CCAGCTTCACGAGCCTCTTCTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018256_1

>merge|NZ_CP018256|1|2344582-2344667|CRISPRCasFinder
CCAGCTTCACGAGCCTCTTCTGAGGTAAATTCATGTGCGTTACCACTGGCATGTGCAGCACGGCCAGCTTCACGAGCTTCTTCTGA

>NZ_CP018256|1|1|2344582-2344667|CRISPRCasFinder
CCAGCTTCACGAGCCTCTTCTGA	GGTAAATTCATGTGCGTTACCACTGGCATGTGCAGCACGG
CCAGCTTCACGAGCTTCTTCTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018256.1\|WP_000482091.1\|2350712_2351192_+\|CinA-family-protein	unknown	unknown	gnl\|CDD\|224463
NZ_CP018256.1\|WP_000251637.1\|2353212_2353356_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018256.1\|WP_000885229.1\|2341768_2342380_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NZ_CP018256.1\|WP_000107128.1\|2334865_2335825_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|381147
NZ_CP018256.1\|WP_000376215.1\|2341156_2341612_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP018256.1\|WP_002017921.1\|2334214_2334328_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018256.1\|WP_000108365.1\|2351476_2351698_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237171
NZ_CP018256.1\|WP_001124846.1\|2342450_2343062_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl\|CDD\|182350
NZ_CP018256.1\|WP_001990041.1\|2346788_2348933_-\|catalase-HPII	unknown	unknown	gnl\|CDD\|236886
NZ_CP018256.1\|WP_000115408.1\|2335821_2339286_-\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP018256.1\|WP_000795915.1\|2343344_2343581_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018256.1\|WP_000983628.1\|2345298_2345712_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018256.1\|WP_001136759.1\|2352514_2352943_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018256.1\|WP_000937460.1\|2333490_2334126_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP018256.1\|WP_000132044.1\|2351803_2352121_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018256.1\|WP_000432330.1\|2345853_2346732_+\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|187613
NZ_CP018256.1\|WP_001145693.1\|2348987_2350397_-\|iron-containing-redox-enzyme-family-protein	unknown	unknown	gnl\|CDD\|379634
NZ_CP018256.1\|WP_001025680.1\|2334437_2334722_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379642
NZ_CP018256.1\|WP_000498477.1\|2352205_2352427_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018256.1\|WP_001990047.1\|2339451_2341098_+\|allantoin-permease	unknown	unknown	gnl\|CDD\|224374

Protein	Function_ID	Function_description	E-value
NZ_CP018256.1\|WP_000482091.1\|2350712_2351192_+\|CinA-family-protein	gnl\|CDD\|224463	COG1546, CinA, Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only].	5.88094e-21
NZ_CP018256.1\|WP_000885229.1\|2341768_2342380_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	2.70108e-23
NZ_CP018256.1\|WP_000107128.1\|2334865_2335825_-\|response-regulator-transcription-factor	gnl\|CDD\|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.21476e-55
NZ_CP018256.1\|WP_000376215.1\|2341156_2341612_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	8.76675e-40
NZ_CP018256.1\|WP_001124846.1\|2342450_2343062_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl\|CDD\|182350	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit.	2.36027e-39
NZ_CP018256.1\|WP_001025680.1\|2334437_2334722_-\|N-acetyltransferase	gnl\|CDD\|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	1.0722e-24
NZ_CP018256.1\|WP_000115408.1\|2335821_2339286_-\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.64852e-57
NZ_CP018256.1\|WP_000108365.1\|2351476_2351698_+\|hypothetical-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	5.30417e-06
NZ_CP018256.1\|WP_000937460.1\|2333490_2334126_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.9036e-64
NZ_CP018256.1\|WP_000432330.1\|2345853_2346732_+\|glucose-1-dehydrogenase	gnl\|CDD\|187613	cd05355, SDR_c1, classical (c) SDR, subgroup 1. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.69173e-160
NZ_CP018256.1\|WP_001145693.1\|2348987_2350397_-\|iron-containing-redox-enzyme-family-protein	gnl\|CDD\|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	1.51279e-18
NZ_CP018256.1\|WP_001990041.1\|2346788_2348933_-\|catalase-HPII	gnl\|CDD\|236886	PRK11249, katE, hydroperoxidase II; Provisional.	0
NZ_CP018256.1\|WP_001990047.1\|2339451_2341098_+\|allantoin-permease	gnl\|CDD\|224374	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism].	9.5172e-23

>NZ_CP018256.1|WP_000795915.1|2343344_2343581_+|hypothetical-protein
MKNQRDAVLGYADEQHAYYIRLIENDAVLGESYGIFCENPESEAAESIMTTLFLKKSFWLNGSEFTDIVKGLHPLTHS
>NZ_CP018256.1|WP_001124846.1|2342450_2343062_-|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MPKKKEFEHGGARENAGRKAQFNEPTKVIRVPESQVNFIKNWLLNNVKTNNQTDFTSKLKIQQVHPNNDKIYHIPLATERVAAGFPSPAQDDIEQALDLNEYLIRNENATFIVKANSLSMLDAGIDIDDPLIVDRSIPAKSGDIVIALIDNDFTVKRLMIDTQFHPPKVWLKAENPDYQNIYIEEGQELVIWGVVTYNLKRMR
>NZ_CP018256.1|WP_000885229.1|2341768_2342380_+|LysE-family-translocator
MAFNIFIAFWSVSILFIITPGADWAYAISAGIKGKVVVPAVAGMLFGHFITILLVAAGVGLLVANNPTALMILTVAGSAYLLWMGINLLLTPPTPNESGSEKAQSWLRWATKGVYVSGLNPKVFLLFLALLPQFIDTTASWSVTTQILAFGVVHIISCAIIYLMVGYGSEAILKTRPQAAQLVGRFSGGLMVVIATCLLIGQI
>NZ_CP018256.1|WP_000376215.1|2341156_2341612_-|Lrp/AsnC-family-transcriptional-regulator
MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLKEGDKQAVEKFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVMKDVVPERLFPIG
>NZ_CP018256.1|WP_001990047.1|2339451_2341098_+|allantoin-permease
MTENDWEIDVMSVSEHPNLDTVQGADSQKAVNETLEDYTLRYAPHSFRRWSPKVVAITALGGIAYLADFSIGASIGMSYGTTNAVFSILFAAIIIFLTGIPLAYYAARYNIDLDLITRGAGFGYIGSVLTSIIFASFTFIFFALEGSIMAQGLLLGLGIPLWAGYLISTVMVIPLVIYGMKALSKLQVWTTPLWLVLMIGPVAYLIYQEPTLVSQFATFTGHEGFAPVDMAAIMLGAGICLSLIMQIGEQIDYLRFMPAKTKENSKAWWAAVISAGPGWVILGAIKQIIGAFLGFYLLTKIPGVNSTEPVQQFNAAFHDMLPGWAALTLAVILVVISQIKINVTNAYSGSLAWTSAYTRISKHYPGRIVFVIVNLAIALALMEGNMFAVLGKILGFYSNFAIAWVVVVATDISINKYVLKLSPKEPEYRRDMLYNVNPVGMVAFLVSAGLSIAAFFGLLGSFLAPYSPIIALVLAFVLTPIMGLLTKGKYYIKSHDDGVKEPRYDAEGTPVATVYHCRVCEQGYERPDIMFSHKHNGTICSLCKTLDA
>NZ_CP018256.1|WP_000115408.1|2335821_2339286_-|response-regulator
MSVMPDTSRPQQAPQRVIKTRREYNIWVADESIEDYALRYAPTSVRKWSPWTVTNTAISTVSFLAMEAIGATMLWQYGFSNALWAAIVVCTIIFLTSWPISYYAAKYNVDVDLLTRGAGFGYIGSTITSLIYASFTFILLAFEAAIMAMALELALGIPQVIGYLISALVILPLVVKGIGFINKVQAVTQPIWLLLLLLPWFFVLWKQPQILSSSLHFVGAVSNSTDFNLYYFGAACTLIFSFVIQIGEQADYLRFLPQKEKNRTAWRFAVFLGGPSWIIFGFLKVLMGMLLMVLAFQLFIPVSELDNPTYLYWVAYQQFIPNPQLALILTLALVCLAQIKINMTNAYAGSLAWSNFFARLTHSHPGRIVWLLFNVFIAIVLMEMGISHAVERILGLYSNIALAWIGAVVADLIICKPLGLSPKGIEFRRAYLYDINPVGVGALLIASVLSMLSYLGFFGLMAKGLASFIALGSAVLCVPVIAYLTTGKYYIARQPEKIQATLVANCVVCERDYELADMAGCPAYNGTICSLCCSLEARCHDLCKPDARWSVQLKKAIWHYLPERWASRLNSRVSLYLLLTLGLSIVLAVSLSLVYIQEKTYLETINAAAVPQLFTLFVKIYTILFLLMSVAAWWLVLNDESRRNAEIETHQQTALLIDEIAAHEVTSKDLQDARIAAERANDAKSRYVIGISHELRTPLNSILGYSQLLQKQEQLSEQGKMALGVISRSGQHLTSLIDGLLDLARIETGKISLNVVDVHFPNFIEQIIQMFQPQFEQKNLQFVYEIGENLPHYVRTDKKRLEQVLINLLGNALKFTTSGTITLKVEYRFQTAYFEIRDTGCGIAEADLERIFNPFERGSNVVQGGFTGIGLGLPIVKLLVDLLGGQLSVTSQLNQGSQFKIKFYLPSKEVVHPISNVYSNQITGYQGERKRILVVDNEAVDRGLVANFLKPLGFMIEEAESGIDCLRRVPIFQPNLILMDLNMPLMGGWETARLLRQNNITNVPILIISANAGEREVNPQDAVLSEDFMLKPIDLNLLLSKIGDKLGLVWIDSKSETLLENNEVQALDLNIYKQEQVAVHTLIQQPENNELLDFPQSLQQLNDLIGQGYIRGIQQTLTQCRQNFPKHNELWEQLEQAIQKFDLKHAQRLIQDKQ
>NZ_CP018256.1|WP_000107128.1|2334865_2335825_-|response-regulator-transcription-factor
MSTQHVSFQQASPNEQAVILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFESCIQLKASPITQFIPVIFMTGLSETEHIVRGFQVGGVDYVTKPLNIEEVLARVKTHLAHAKLLQQQKQVIDATETAILALDVHGKIVWKTQKASDLLNQYLPELEGFEAGLKAWFSDLEHEKDPKKLTSCSYSTPSQQLQLLLLTPWETEPSVAKNYLIQIKTSTPALEMADILKYCPQLTQREAEVMHWLLLGKTNKDIAEILELSPRTVNKHLEHVFEKLCVENRTAAVAHINSLVQEFH
>NZ_CP018256.1|WP_001025680.1|2334437_2334722_-|N-acetyltransferase
MNIQQKDDTKHGSFSLLDGETVAGEMTYTWAGESMLIIDATDVNENYRGQGVGRQLLDALVAFVREKDVKVIPLCPYAKSVFDKDPSIGDVLRK
>NZ_CP018256.1|WP_002017921.1|2334214_2334328_+|hypothetical-protein
MCNKFIFFPIGLKLFLLDKLFYKFDKFDLAIENLQIS
>NZ_CP018256.1|WP_000937460.1|2333490_2334126_-|amino-acid-ABC-transporter-permease
MLPQFFSATLTTLKISIISIILAIIVGLICSILITYHVRVLNRIAQFYIELSRNTPLLIQLFFLYYGLPKLGIKIDGFACGVIGLTFLGGSYMAEAFRAGLQSVAKGQIDSAKSIGLKPTQIFRYVIFPQALAISIPAIGANCLFLIKESSVVSAIAVVELLFVTKDLIGMDYKTTEALFLLIMAYLIILLPVSILTSYLEHRSRKVSHGT
>NZ_CP018256.1|WP_000983628.1|2345298_2345712_+|hypothetical-protein
MMQPTHTHSTLQYIHISVPEILLSNIQIKNSWQDYNQEWSYRLDPPHASHPFQRDLYIIKSKNIETEDIKKILDNIVVKNSKNKDDLKNIVEAETVIKEILDLSNYIPIENWLNDTGNRSIVESMIDKNKVKLLDII
>NZ_CP018256.1|WP_000432330.1|2345853_2346732_+|glucose-1-dehydrogenase
MENTTNQYPSEVPAQVQPHQPGDQEKMHPEPEIIKASHKGSEKLKGKVAVISGGDSGIGRSVAVLFAREGADIAVLYLKEDQDAEITKQLIEKEGQQCLLLKGDISDPDLAKQNIDKVLQHFGKINILVNNAGVQYQQKEIESISNEQLEKTFKTNIFTMFYLTKEAIPYMEEGDSIINTTSITSYQGHDELIDYASTKGAITSFTRSLSNNLMKQKKGIRVNGVAPGPIWTPLIPSSFDAETVEKFGKDTPMGRMGQPSEVAPAYLFLASDDASYITGQVIHVNGGQIVNG
>NZ_CP018256.1|WP_001990041.1|2346788_2348933_-|catalase-HPII
MDMNDNTKSTNKTSEMAGADAANKANTTQKTEQLDTVRDDATNEALTTNQGVKIADNQNSLRAGIRGSTLLEDFILREKITHFDHERIPERIVHARGVGAHGYFQAYEGNERLTKAGFLTDPTIQTPIFVRFSTVQGPRGSADTVRDIRGFAIKFYTQEGNFDLVGNNAPVFFVQDGIKFPDFVHAVKPEPDTEIPTGATAHDTFWDFVSLVPESAHAVIWAMSDRAIPRNLRSIQGFGVHTFRLINAEGKSHFVKFHWTPKQGLSALVWDEAQKLAGKDPDFHRRDLYEAIEHGFYPEWELGVQIVEEEDEMNFDFDLLDPTKIIPEELVPVTPIGRFVLNRNVDNFFAETEQVAFCPGHVVPGIDFTDDPLLQARLFSYTDTQLSRLGGPNFHQIPINKPVCPFHNNQRDGIHQHTIHKGQAAYQPNSIDGNWPVETPPAASNGGFESYPEKISGHKLRQRSETFSDYFSQPRLYYKSLAPHEQKHVVDAYTFELSKVQRKHIRERQVQQILANIDLDLARQVGANLGIEVPDLTLSYKKTAVEKSAKLSFLAFPPEDIQGRKVAVLIHNMVKSDALEAIKNWAIKEGVILHLLAPSLAPVKDHKDNVIVADGMQMSEPSIAYDAVIIPDGDNLNTVMQDGVARHYLLEAYKHLKPIVFLGNKSDLLEPLGLVADEGTLIEDEFQHVAEKFKNLIKAHRVWSREQIAAHVPA
>NZ_CP018256.1|WP_001145693.1|2348987_2350397_-|iron-containing-redox-enzyme-family-protein
MPVVVKKRLLDLLQDNQQNYYELFVFFLDPDVSSFEKEKKARDFLVKEIDKLEMKEIDFPSDINLIKAWCENDNKKNCQEFQAYLNRRQSGQDREYFKNVAQAFEFLIKVSPTKKVDGAWLYSSVHYWNDPIFHELIITYLEELGLGEPKANHVCIYDDLLRSLGLDSFDLLLEDEYYHQAVVQLALGYAPPEFIPEIVGFNLGYEQLPLHLLISNYELAELGIDSKYFNLHITIDNIDNGHAYKAIKVIEDIYNQYRDKELFLTKLKRGFALNNHGVSSSNIIKNLNTEDFVHRIFKRKALVGQLIHNETRQFGCKTINQWLSNPDDIAGLITHLTEHKWIKFNTDPEQSVFWRMINEENGKMFGVFNPVERQIIHDWIAGSDHSSSFLAYSRELKNSQRIQDYLFSYISDGELDALQERVQQSSDLAIKICKLTPFLAPDSHHKSIGLWSTRKYVELLFPYLGTFKN
>NZ_CP018256.1|WP_000482091.1|2350712_2351192_+|CinA-family-protein
MFNKCCELLAKEKIKIAFFESASAGYLAYRFSLSPYSGDILIGSLVSYDLRVKENTLHISEELIEKYTAESMQVTVEMINKGKELLHADLYVACTGLLKKGGSETPEKPVGTFFYSIYYKNNFYNFRRVLRGPAFLKLRKLIYYVTQDIKLIILEDKRR
>NZ_CP018256.1|WP_000108365.1|2351476_2351698_+|hypothetical-protein
MSTTNNQANQRNNQQQQQQQNDNRNQQQHGNQQQNDQQQQNNQQQQQNDNRGQQQGSNQKDSGQQNSNNNQQR
>NZ_CP018256.1|WP_000132044.1|2351803_2352121_+|hypothetical-protein
MTDQNTDHAQLVAGDHNYSDSRWRESYLTRPYYQEAQLTTPDLDYDRDFSAAYELGHRARSESKEGTQFEDMEGSLQQKWEELKAESRLKWEHAKQAIKDAWDDI
>NZ_CP018256.1|WP_000498477.1|2352205_2352427_-|hypothetical-protein
MFVYFTDGTCINDSEIYGVKAKYEQNKYVVEVTIKPTHVLATTPSVQFKKEVFDDPNLANQYLSHNFNMPPFF
>NZ_CP018256.1|WP_001136759.1|2352514_2352943_-|hypothetical-protein
MPQYLKIAEKIYQNVKEKKGFTDDPMEDLNNLMIELRQEIKGTKLKLLYNYIDFAEILIKPLQESKIKLDLSLIPKSKNTQEFVLWLAGFIERITTGGQEKLPPIRAKITLPAYAYEETYPSQKKPVNNGEEIIEYFKKNQS
>NZ_CP018256.1|WP_000251637.1|2353212_2353356_-|hypothetical-protein
MVRIFCAVSMVLAIAMGMSACQDRNSRNDGMHEASDPATSHDMNKNS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1167535 : 1182332

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001187844.1\|1167535_1168084_-	GTP cyclohydrolase I FolE	A0A0P0HSD2	Acinetobacter_phage	1.7e-97	100.0
WP_000893683.1\|1168346_1169846_+	xanthine dehydrogenase small subunit	A0A0P0IVM8	Acinetobacter_phage	6.1e-286	100.0
WP_001076817.1\|1169847_1172223_+	xanthine dehydrogenase molybdopterin binding subunit	A0A0P0I429	Acinetobacter_phage	0.0e+00	100.0
WP_001164226.1\|1172229_1173213_+	xanthine dehydrogenase accessory protein XdhC	A0A0P0IKN7	Acinetobacter_phage	2.0e-189	100.0
WP_000066126.1\|1173223_1173919_-	Smr/MutS family protein	A0A0P0IDT4	Acinetobacter_phage	5.8e-122	100.0
WP_000608304.1\|1173928_1174735_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	7.9e-147	100.0
WP_001982145.1\|1174744_1175794_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	9.8e-190	100.0
WP_000281127.1\|1176149_1178882_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	0.0e+00	99.9
WP_000960548.1\|1178961_1181661_+	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	0.0e+00	100.0
WP_000566784.1\|1181756_1182332_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.2e-110	100.0

DBSCAN-SWA_2

1345292 : 1366137

Escherichia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067858.1\|1345292_1345997_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000018326.1\|1346250_1347066_+	aminoglycoside O-phosphotransferase APH(3')-Ia	A0A193DTG4	Autographa_californica_nuclear_polyhedrosis_virus	4.3e-161	98.5
WP_001067858.1\|1347178_1347883_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_014454105.1\|1348912_1349467_+	aminoglycoside N-acetyltransferase AAC(6')-Ib'	NA	NA	NA	NA
WP_002075262.1\|1349559_1350192_+	type B-3 chloramphenicol O-acetyltransferase CatB8	A0A2R8FE91	Brazilian_cedratvirus	3.5e-25	40.1
WP_001206316.1\|1350249_1351041_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
WP_000679427.1\|1351204_1351552_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|1351545_1352385_+	sulfonamide-resistant dihydropteroate synthase Sul1	NA	NA	NA	NA
WP_000050481.1\|1352789_1354331_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000359986.1\|1355730_1356504_+	ArmA family 16S rRNA (guanine(1405)-N(7))-methyltransferase	NA	NA	NA	NA
WP_077252464.1\|1356484_1356766_-	hypothetical protein	NA	NA	NA	NA
WP_002026779.1\|1356985_1357171_-	hypothetical protein	NA	NA	NA	NA
WP_002001451.1\|1357219_1358404_+\|transposase	IS4-like element ISEc29 family transposase	A0A0F7LAS3	uncultured_marine_virus	4.5e-50	35.4
WP_000052512.1\|1358802_1360278_+	ABC-F type ribosomal protection protein Msr(E)	A0A1B0RXA0	Streptococcus_phage	2.3e-160	59.0
WP_000155092.1\|1360333_1361218_+	Mph(E) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_000753551.1\|1361861_1363421_-\|transposase	IS66-like element ISAba24 family transposase	S5VTD3	Leptospira_phage	4.0e-70	34.2
WP_000781558.1\|1363513_1363870_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.6e-22	45.9
WP_000555098.1\|1363872_1364157_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_001067858.1\|1365432_1366137_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6

DBSCAN-SWA_3

1544752 : 1597703

Acinetobacter_phage(95.59%)

transposase,integrase,capsid

attL 1538775:1538789|attR 1563715:1563729

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1538775:1538789	attL	NA	NA	NA	NA
WP_000773626.1\|1544752_1546015_+\|integrase	integrase family protein	A0A0P0IKP2	Acinetobacter_phage	3.6e-247	99.0
WP_000910238.1\|1546020_1546290_-	hypothetical protein	A0A0N7IRE8	Acinetobacter_phage	3.5e-43	100.0
WP_000005652.1\|1546290_1546548_-	hypothetical protein	A0A0P0J0B1	Acinetobacter_phage	3.2e-46	96.5
WP_000048742.1\|1546551_1546836_-	hypothetical protein	A0A0P0HSI5	Acinetobacter_phage	1.3e-43	94.7
WP_000566309.1\|1546828_1547239_-	hypothetical protein	A0A0P0I8H3	Acinetobacter_phage	7.6e-13	100.0
WP_000654847.1\|1547242_1547488_-	hypothetical protein	A0A0P0IVN4	Acinetobacter_phage	1.5e-40	100.0
WP_000698522.1\|1547489_1548491_-	hypothetical protein	A0A0P0IKV7	Acinetobacter_phage	6.5e-183	97.3
WP_001207471.1\|1548487_1549609_-	ATP-binding protein	A0A0N7IRE0	Acinetobacter_phage	5.2e-213	100.0
WP_000064462.1\|1549620_1549944_-	hypothetical protein	A0A0D4DCB5	Acinetobacter_phage	9.7e-56	96.3
WP_001101036.1\|1549946_1550387_-	hypothetical protein	A0A0N7IRE9	Acinetobacter_phage	3.1e-73	95.9
WP_001129670.1\|1550593_1551097_-	hypothetical protein	A0A0P0I896	Acinetobacter_phage	1.2e-65	82.6
WP_000048049.1\|1551099_1552101_-	hypothetical protein	A0A0P0IRH5	Acinetobacter_phage	4.2e-182	100.0
WP_000370485.1\|1552151_1552367_-	hypothetical protein	A0A0P0IKK4	Acinetobacter_phage	9.4e-31	98.6
WP_001093662.1\|1552381_1553146_-	LexA family transcriptional regulator	A0A0P0J076	Acinetobacter_phage	1.6e-144	98.8
WP_000996060.1\|1553254_1553506_+	hypothetical protein	A0A0N7IRE1	Acinetobacter_phage	2.4e-38	95.2
WP_000041063.1\|1553515_1553872_+	hypothetical protein	J7I452	Acinetobacter_phage	8.8e-58	98.3
WP_001095598.1\|1553927_1554203_+	hypothetical protein	A0A0P0IVP2	Acinetobacter_phage	8.9e-42	100.0
WP_000094160.1\|1554199_1554496_+	hypothetical protein	J7HXM0	Acinetobacter_phage	1.7e-46	95.9
WP_001267985.1\|1554492_1554855_+	hypothetical protein	A0A0D4DBI9	Acinetobacter_phage	2.4e-55	99.1
WP_000280081.1\|1554847_1555777_+	YdaU family protein	A0A0P0I481	Acinetobacter_phage	4.3e-173	100.0
WP_000544506.1\|1555769_1556519_+	hypothetical protein	A0A0N7IRF0	Acinetobacter_phage	1.2e-136	98.4
WP_001031749.1\|1556515_1556650_+	putative phage replication protein	A0A0P0IR92	Acinetobacter_phage	1.1e-18	100.0
WP_000648413.1\|1556636_1557059_+	hypothetical protein	A0A0P0I8A5	Acinetobacter_phage	1.0e-76	100.0
WP_002018225.1\|1557108_1557471_+	hypothetical protein	A0A0N7IRE2	Acinetobacter_phage	1.0e-69	100.0
WP_001288422.1\|1557463_1557688_+	hypothetical protein	A0A0P0IY41	Acinetobacter_phage	9.4e-34	100.0
WP_000100186.1\|1557687_1558089_+	DUF559 domain-containing protein	A0A0P0IKL1	Acinetobacter_phage	1.9e-69	100.0
WP_000959662.1\|1558099_1558852_+	hypothetical protein	A0A0P0J081	Acinetobacter_phage	8.7e-140	100.0
WP_001017703.1\|1558995_1559214_+	hypothetical protein	NA	NA	NA	NA
WP_001005050.1\|1559480_1559834_+	hypothetical protein	NA	NA	NA	NA
WP_000152665.1\|1560033_1560270_+	hypothetical protein	NA	NA	NA	NA
WP_000195750.1\|1560931_1561387_+	hypothetical protein	A0A0P0HSF5	Acinetobacter_phage	7.2e-81	96.7
WP_000378511.1\|1561447_1561915_+	hypothetical protein	A0A0P0IRI6	Acinetobacter_phage	3.6e-67	81.9
WP_000372131.1\|1561883_1562525_+	hypothetical protein	A0A0P0I8J9	Acinetobacter_phage	3.6e-118	93.9
WP_000212703.1\|1562584_1563142_+	DUF2280 domain-containing protein	A0A0P0IKR0	Acinetobacter_phage	2.5e-83	100.0
WP_000077244.1\|1563125_1564442_+	hypothetical protein	A0A0N7IRE3	Acinetobacter_phage	1.6e-266	100.0
1563715:1563729	attR	NA	NA	NA	NA
WP_000301497.1\|1564481_1565828_+	DUF4055 domain-containing protein	A0A0P0IDW1	Acinetobacter_phage	6.5e-255	100.0
WP_000146969.1\|1565837_1566944_+\|capsid	minor capsid protein	A0A0P0IR98	Acinetobacter_phage	1.2e-206	100.0
WP_000965231.1\|1566952_1567381_+	hypothetical protein	J7I4P3	Acinetobacter_phage	5.2e-73	100.0
WP_000004361.1\|1567479_1567722_+	hypothetical protein	A0A0P0IY55	Acinetobacter_phage	2.1e-39	100.0
WP_001139861.1\|1567939_1568131_+	hypothetical protein	A0A0P0IKM2	Acinetobacter_phage	1.7e-28	100.0
WP_001112409.1\|1568238_1568994_+	hypothetical protein	A0A0P0J090	Acinetobacter_phage	1.6e-130	100.0
WP_000502917.1\|1569007_1569958_+	hypothetical protein	A0A0P0HSG2	Acinetobacter_phage	1.1e-179	100.0
WP_000524488.1\|1570002_1570338_+	hypothetical protein	A0A0N7IRE4	Acinetobacter_phage	2.7e-53	100.0
WP_000008470.1\|1570341_1570722_+	hypothetical protein	A0A0P0IVQ3	Acinetobacter_phage	4.8e-62	100.0
WP_000524217.1\|1570722_1571091_+	glutamate 5-kinase	A0A0P0I456	Acinetobacter_phage	2.6e-65	100.0
WP_000247948.1\|1571099_1571504_+	hypothetical protein	A0A0P0IKR8	Acinetobacter_phage	4.6e-71	100.0
WP_002055488.1\|1571475_1571844_+	hypothetical protein	A0A0P0IDX0	Acinetobacter_phage	5.0e-56	99.1
WP_001251850.1\|1571845_1572244_+	hypothetical protein	A0A0P0IRA6	Acinetobacter_phage	2.2e-73	100.0
WP_001277687.1\|1572245_1572464_+	hypothetical protein	A0A0P0I8C2	Acinetobacter_phage	2.4e-34	100.0
WP_000064599.1\|1572557_1572911_+	hypothetical protein	J7I469	Acinetobacter_phage	1.2e-59	100.0
WP_000002422.1\|1572910_1574146_+	hypothetical protein	A0A0N7IRE5	Acinetobacter_phage	2.8e-188	80.1
WP_000094250.1\|1574198_1575116_+	hypothetical protein	A0A0P0IL42	Acinetobacter_phage	7.3e-165	96.4
WP_001185608.1\|1575185_1575701_+	hypothetical protein	A0A0N7IRG3	Acinetobacter_phage	2.0e-71	97.1
WP_000838146.1\|1576026_1576209_+	type II toxin-antitoxin system HicA family toxin	A0A0D4DC32	Acinetobacter_phage	7.4e-29	100.0
WP_000966688.1\|1576301_1576706_+	type II toxin-antitoxin system HicB family antitoxin	A0A0D4DCG1	Acinetobacter_phage	3.9e-70	100.0
WP_014466185.1\|1576804_1576981_+	hypothetical protein	A0A0R6PI25	Moraxella_phage	4.8e-09	59.6
WP_000523922.1\|1576989_1577313_+	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_000720608.1\|1577344_1578139_+	hypothetical protein	A0A2H4J0E0	uncultured_Caudovirales_phage	1.7e-05	42.2
WP_000763623.1\|1578187_1578427_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_001103649.1\|1578549_1578705_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_000835645.1\|1578701_1579694_+	KilA-N domain-containing protein	A0A0P0ZCS0	Stx2-converting_phage	9.7e-22	46.9
WP_000046563.1\|1579763_1584071_+	tape measure protein	A0A0D4DC37	Acinetobacter_phage	0.0e+00	98.3
WP_000937383.1\|1584145_1584898_+	hypothetical protein	J7HXF9	Acinetobacter_phage	1.2e-32	34.4
WP_000246069.1\|1584901_1585294_+	hypothetical protein	NA	NA	NA	NA
WP_000277443.1\|1585358_1585757_+	hypothetical protein	J7I0X8	Acinetobacter_phage	1.3e-73	100.0
WP_000368373.1\|1585756_1586263_+	DUF1833 family protein	A0A0P0IKN4	Acinetobacter_phage	5.5e-90	95.2
WP_000835165.1\|1586259_1586622_+	hypothetical protein	J7I4R1	Acinetobacter_phage	1.2e-65	99.2
WP_000590505.1\|1586614_1590061_+	hypothetical protein	J7HXG3	Acinetobacter_phage	0.0e+00	100.0
WP_000433918.1\|1590128_1590518_+	hypothetical protein	J7I481	Acinetobacter_phage	2.5e-66	100.0
WP_000720514.1\|1590716_1591058_+	hypothetical protein	NA	NA	NA	NA
WP_000735265.1\|1591061_1591388_+	hypothetical protein	NA	NA	NA	NA
WP_001226299.1\|1591444_1591936_+	hypothetical protein	NA	NA	NA	NA
WP_000124482.1\|1591955_1592216_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_000096283.1\|1592381_1593281_+	alpha/beta hydrolase	A0A0P0J0J7	Acinetobacter_phage	4.2e-149	85.4
WP_001019716.1\|1593619_1594165_+	N-acetylmuramidase	J7I0Y1	Acinetobacter_phage	2.6e-101	98.9
WP_000999701.1\|1594353_1595034_+	hypothetical protein	A0A0P0IKS6	Acinetobacter_phage	4.6e-116	100.0
WP_001109862.1\|1595044_1595692_+	hypothetical protein	J7I4R4	Acinetobacter_phage	3.6e-118	100.0
WP_000151893.1\|1595698_1596292_+	hypothetical protein	A0A0P0HSM0	Acinetobacter_phage	5.1e-103	100.0
WP_085942227.1\|1596537_1597703_-\|transposase	IS3-like element ISAba22 family transposase	A0A0P0I4A4	Acinetobacter_phage	7.1e-165	100.0

DBSCAN-SWA_4

2729492 : 2758166

Acinetobacter_phage(93.55%)

terminase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001019739.1\|2729492_2730038_-	N-acetylmuramidase	A0A0B5L5G7	Acinetobacter_phage	4.7e-103	100.0
WP_000433907.1\|2730079_2730469_-	hypothetical protein	A0A0P0I8L9	Acinetobacter_phage	3.3e-66	99.2
WP_000598554.1\|2730536_2733962_-	hypothetical protein	A0A0P0HSH9	Acinetobacter_phage	0.0e+00	94.2
WP_000835160.1\|2733954_2734317_-	hypothetical protein	A0A0P0J0A2	Acinetobacter_phage	8.1e-51	79.2
WP_000368388.1\|2734313_2734820_-	DUF1833 family protein	J7HXQ5	Acinetobacter_phage	1.5e-90	97.0
WP_000277448.1\|2734819_2735218_-	hypothetical protein	J7I0X8	Acinetobacter_phage	4.1e-72	97.7
WP_000721057.1\|2735310_2735898_-	hypothetical protein	NA	NA	NA	NA
WP_000046573.1\|2735988_2740299_-	tape measure protein	A0A0D4DC37	Acinetobacter_phage	0.0e+00	98.3
WP_001275792.1\|2740426_2740690_-	hypothetical protein	NA	NA	NA	NA
WP_000721572.1\|2740691_2741372_-	hypothetical protein	A0A0R6PJY5	Moraxella_phage	2.5e-53	49.3
WP_000274931.1\|2741476_2741935_-	helix-turn-helix domain-containing protein	A0A0P0IRJ4	Acinetobacter_phage	1.1e-84	100.0
WP_000335868.1\|2741943_2742243_-	DUF4258 domain-containing protein	A0A0P0IE58	Acinetobacter_phage	7.4e-50	100.0
WP_001185585.1\|2742745_2743261_-	hypothetical protein	A0A0N7IRG3	Acinetobacter_phage	2.5e-77	96.6
WP_000094278.1\|2743330_2744248_-	hypothetical protein	J7HXP7	Acinetobacter_phage	2.0e-170	100.0
WP_000002408.1\|2744300_2745479_-	hypothetical protein	A0A0D4DCQ4	Acinetobacter_phage	1.2e-103	66.3
WP_000064593.1\|2745478_2745832_-	hypothetical protein	A0A0D4DCF7	Acinetobacter_phage	3.3e-57	96.6
WP_000749909.1\|2745928_2746450_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_001277696.1\|2746558_2746777_-	hypothetical protein	A0A0P0I8C2	Acinetobacter_phage	1.2e-28	94.2
WP_001984404.1\|2746778_2747222_-	hypothetical protein	A0A0D4DBX3	Acinetobacter_phage	2.0e-75	94.6
WP_000539749.1\|2747178_2747547_-	hypothetical protein	A0A0D4DBN1	Acinetobacter_phage	2.0e-52	82.8
WP_000248411.1\|2747518_2747929_-	hypothetical protein	A0A0P0IKR8	Acinetobacter_phage	7.7e-50	73.3
WP_000235282.1\|2747980_2748274_-	hypothetical protein	NA	NA	NA	NA
WP_000540685.1\|2748281_2748479_-	hypothetical protein	NA	NA	NA	NA
WP_000524257.1\|2748547_2748916_-	hypothetical protein	J7I467	Acinetobacter_phage	8.7e-61	92.6
WP_000008459.1\|2748916_2749297_-	hypothetical protein	A0A0P0IVQ3	Acinetobacter_phage	6.9e-53	84.9
WP_000524488.1\|2749300_2749636_-	hypothetical protein	A0A0N7IRE4	Acinetobacter_phage	2.7e-53	100.0
WP_000852265.1\|2749680_2750631_-	hypothetical protein	A0A0P0HSG2	Acinetobacter_phage	3.7e-172	94.9
WP_000056390.1\|2750644_2751436_-	hypothetical protein	A0A0P0J090	Acinetobacter_phage	2.3e-90	74.2
WP_000589038.1\|2751522_2751837_-	hypothetical protein	A0A0S3UFT8	Pseudomonas_phage	5.2e-14	50.5
WP_001291451.1\|2751888_2752041_-	hypothetical protein	NA	NA	NA	NA
WP_000004550.1\|2752056_2752287_-	hypothetical protein	NA	NA	NA	NA
WP_000146970.1\|2752283_2753390_-\|capsid	minor capsid protein	A0A0P0IR98	Acinetobacter_phage	2.1e-190	90.2
WP_000301495.1\|2753399_2754740_-	DUF4055 domain-containing protein	A0A0P0IDW1	Acinetobacter_phage	3.4e-235	92.2
WP_001132930.1\|2754779_2756072_-\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	6.4e-215	86.0
WP_000729387.1\|2756031_2756547_-	DUF2280 domain-containing protein	A0A1B1P9C2	Acinetobacter_phage	3.2e-45	61.3
WP_000435230.1\|2756605_2757247_-	hypothetical protein	A0A0D4DBV4	Acinetobacter_phage	6.3e-115	88.7
WP_000378523.1\|2757215_2757650_-	hypothetical protein	A0A0P0IVP9	Acinetobacter_phage	7.4e-67	84.7
WP_001136773.1\|2757710_2758166_-	hypothetical protein	A0A0P0HSF5	Acinetobacter_phage	2.7e-80	95.4

DBSCAN-SWA_5

2762124 : 2774472

Acinetobacter_phage(95.65%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001277128.1\|2762124_2762601_-	hypothetical protein	A0A2H4J548	uncultured_Caudovirales_phage	1.2e-25	40.3
WP_000100162.1\|2762597_2762999_-	DUF559 domain-containing protein	A0A0P0I8E8	Acinetobacter_phage	2.6e-66	96.2
WP_000462878.1\|2762998_2763391_-	hypothetical protein	J7HXM5	Acinetobacter_phage	1.2e-07	57.8
WP_000647826.1\|2763383_2763722_-	hypothetical protein	A0A0P0IKW4	Acinetobacter_phage	1.1e-30	56.3
WP_001003671.1\|2763718_2764519_-	hypothetical protein	A0A0P0IDV1	Acinetobacter_phage	2.8e-144	95.5
WP_000064627.1\|2764521_2765403_-	replication protein	A0A0P0IKQ2	Acinetobacter_phage	3.3e-138	95.2
WP_000602535.1\|2765395_2765620_-	hypothetical protein	A0A0P0I444	Acinetobacter_phage	3.2e-34	97.3
WP_001180660.1\|2765691_2765964_-	hypothetical protein	J7I0V3	Acinetobacter_phage	7.2e-36	90.0
WP_000048916.1\|2766025_2766346_-	hypothetical protein	A0A0P0HSE9	Acinetobacter_phage	1.2e-42	87.7
WP_000703023.1\|2766356_2766545_-	hypothetical protein	NA	NA	NA	NA
WP_000052252.1\|2766649_2767402_+	LexA family transcriptional regulator	J7I4M9	Acinetobacter_phage	5.5e-102	74.3
WP_000370485.1\|2767416_2767632_+	hypothetical protein	A0A0P0IKK4	Acinetobacter_phage	9.4e-31	98.6
WP_000048052.1\|2767683_2768691_+	hypothetical protein	A0A0P0IY33	Acinetobacter_phage	2.9e-183	100.0
WP_001129676.1\|2768692_2769196_+	hypothetical protein	A0A0P0I896	Acinetobacter_phage	1.1e-77	100.0
WP_000845537.1\|2769334_2769538_+	hypothetical protein	A0A0P0IKZ8	Acinetobacter_phage	1.2e-27	100.0
WP_000051960.1\|2769544_2769787_-	hypothetical protein	A0A0P0I4B0	Acinetobacter_phage	5.2e-38	100.0
WP_001101038.1\|2769980_2770424_+	hypothetical protein	A0A0N7IRF7	Acinetobacter_phage	1.7e-71	94.5
WP_000656405.1\|2770423_2770714_+	hypothetical protein	A0A0P0IDU2	Acinetobacter_phage	5.1e-48	95.8
WP_000064463.1\|2770706_2771030_+	hypothetical protein	A0A0D4DCB5	Acinetobacter_phage	4.8e-55	95.3
WP_001207474.1\|2771041_2772163_+	ATP-binding protein	A0A0N7IRE0	Acinetobacter_phage	2.8e-211	99.5
WP_000698529.1\|2772159_2773092_+	hypothetical protein	A0A0P0I438	Acinetobacter_phage	2.2e-137	80.0
WP_000654846.1\|2773093_2773345_+	hypothetical protein	A0A0P0IVN4	Acinetobacter_phage	6.4e-39	100.0
WP_000147323.1\|2773345_2773753_+	hypothetical protein	A0A0P0IRG7	Acinetobacter_phage	7.5e-13	52.2
WP_000004579.1\|2773749_2774472_+	hypothetical protein	A0A0P0HSE1	Acinetobacter_phage	1.7e-55	88.2

DBSCAN-SWA_6

2993604 : 3001701

Acinetobacter_phage(57.14%)

integrase

attL 2994449:2994463|attR 3006361:3006375

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001260065.1\|2993604_2993976_+	hypothetical protein	A0A0D4DCB5	Acinetobacter_phage	1.4e-10	40.6
WP_000643997.1\|2994146_2994827_+	DNA polymerase III subunit epsilon	NA	NA	NA	NA
2994449:2994463	attL	NA	NA	NA	NA
WP_000805204.1\|2994839_2995868_+	ead/Ea22-like family protein	A0A2I7QY11	Vibrio_phage	3.8e-13	29.0
WP_000986115.1\|2996008_2996299_+	hypothetical protein	NA	NA	NA	NA
WP_000464381.1\|2996299_2996479_+	hypothetical protein	NA	NA	NA	NA
WP_000609004.1\|2996471_2997008_+	hypothetical protein	NA	NA	NA	NA
WP_000578497.1\|2997004_2997514_+	phage protein	A0A0P0I8H3	Acinetobacter_phage	1.6e-33	87.8
WP_000028957.1\|2997510_2997720_+	hypothetical protein	A0A0P0IRG7	Acinetobacter_phage	6.3e-32	94.2
WP_001292077.1\|2997716_2997932_+	hypothetical protein	I2GUB6	Acinetobacter_phage	8.5e-32	92.9
WP_000119264.1\|2997932_2998103_+	hypothetical protein	A0A2H4JBW6	uncultured_Caudovirales_phage	2.4e-13	69.2
WP_000527288.1\|2998109_2999102_-	FRG domain-containing protein	NA	NA	NA	NA
WP_000549863.1\|2999216_2999672_-	hypothetical protein	NA	NA	NA	NA
WP_001076477.1\|2999662_3000547_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000947475.1\|3000543_3001701_-\|integrase	site-specific integrase	A0A2H4J339	uncultured_Caudovirales_phage	4.9e-134	63.0
3006361:3006375	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3667356 : 3724428

Staphylococcus_phage(14.29%)

transposase,integrase,tRNA

attL 3700200:3700214|attR 3732471:3732485

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000216739.1\|3667356_3668289_+\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
WP_000908243.1\|3669558_3670905_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_000942498.1\|3671064_3671316_-	hypothetical protein	NA	NA	NA	NA
WP_001278225.1\|3671336_3673190_-	ferrous iron transporter B	NA	NA	NA	NA
WP_001991212.1\|3673186_3673450_-	ferrous iron transport protein A	NA	NA	NA	NA
WP_000608730.1\|3673593_3674514_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	6.7e-33	30.7
WP_000011159.1\|3674660_3675476_+	DsbC family protein	NA	NA	NA	NA
WP_000805827.1\|3675720_3677022_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_000063593.1\|3677077_3678217_+	threonine synthase	NA	NA	NA	NA
WP_003384760.1\|3678323_3679370_-	D-alanyl-D-alanine endopeptidase PBP7/8	NA	NA	NA	NA
WP_000633799.1\|3679582_3680218_+	response regulator	NA	NA	NA	NA
WP_002001070.1\|3680273_3681797_+	PAS domain-containing sensor histidine kinase	A0A1V0SGX0	Hokovirus	2.3e-06	26.3
WP_000840549.1\|3681821_3683243_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_000942504.1\|3683246_3684431_-	peptidase S41	A0A0R6PIZ1	Moraxella_phage	8.3e-12	23.0
WP_000128749.1\|3684446_3685994_-	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_000881094.1\|3686119_3687190_-	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_000586912.1\|3687189_3688290_-	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_000673449.1\|3688433_3689882_+	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	5.5e-50	36.4
WP_001151592.1\|3689874_3690282_+	DNA polymerase III subunit chi	NA	NA	NA	NA
WP_001988710.1\|3690320_3690959_+	hypothetical protein	NA	NA	NA	NA
WP_000354154.1\|3691089_3691308_+	hypothetical protein	NA	NA	NA	NA
WP_000493866.1\|3691367_3692027_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.5e-34	38.6
WP_001083669.1\|3692069_3693362_-	DNA adenine methylase	A0A0P0BWH0	Ostreococcus_mediterraneus_virus	2.5e-38	32.6
WP_001292506.1\|3693358_3694444_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.1e-48	36.6
WP_000543541.1\|3694459_3694918_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_000738520.1\|3695075_3696473_-	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	5.4e-34	31.2
WP_000780326.1\|3696530_3696869_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_000894500.1\|3697148_3697376_+	accessory factor UbiK family protein	NA	NA	NA	NA
WP_000010465.1\|3697441_3698299_+	ATP-binding protein	NA	NA	NA	NA
WP_001144971.1\|3698381_3700169_+	hypothetical protein	NA	NA	NA	NA
3700200:3700214	attL	NA	NA	NA	NA
WP_001082319.1\|3700551_3701355_+	aminoglycoside O-phosphotransferase APH(3'')-Ib	Q75ZG1	Hepacivirus	4.9e-24	34.3
WP_000480968.1\|3701354_3702191_+	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_000743213.1\|3702310_3702535_+	hypothetical protein	NA	NA	NA	NA
WP_001120888.1\|3702745_3704239_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000512977.1\|3704476_3704881_+	hypothetical protein	NA	NA	NA	NA
WP_000088605.1\|3704858_3705482_-	tetracycline resistance transcriptional repressor TetR(B)	NA	NA	NA	NA
WP_001089073.1\|3705563_3706781_+	tetracycline efflux MFS transporter Tet(B)	A0A2H4UVM2	Bodo_saltans_virus	3.0e-09	24.4
WP_001144965.1\|3706863_3708660_+	hypothetical protein	NA	NA	NA	NA
WP_000953322.1\|3708954_3710442_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	8.3e-219	79.4
WP_000034564.1\|3710454_3711306_+	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	8.2e-70	45.9
WP_001095006.1\|3711373_3711673_+	hypothetical protein	NA	NA	NA	NA
WP_000529372.1\|3711745_3712117_+	hypothetical protein	NA	NA	NA	NA
WP_002017214.1\|3712491_3713922_-	hypothetical protein	NA	NA	NA	NA
WP_000081835.1\|3713914_3715030_-	TniQ family protein	NA	NA	NA	NA
WP_000417085.1\|3715059_3715980_-	TniB family NTP-binding protein	NA	NA	NA	NA
WP_000573060.1\|3715984_3717895_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_000736396.1\|3717895_3718606_-\|transposase	heteromeric transposase endonuclease subunit TnsA	I6WI48	Vibriophage	4.1e-06	29.3
WP_071543477.1\|3718810_3719104_+	hypothetical protein	NA	NA	NA	NA
WP_000251875.1\|3718997_3719300_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001043260.1\|3719386_3720202_-	sulfonamide-resistant dihydropteroate synthase Sul2	NA	NA	NA	NA
WP_085940413.1\|3720294_3721384_+\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
WP_000573066.1\|3721806_3723717_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_000736393.1\|3723717_3724428_-\|transposase	heteromeric transposase endonuclease subunit TnsA	I6WI48	Vibriophage	5.3e-06	29.3
3732471:3732485	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018257

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP018256

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection