CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018136	Streptococcus pneumoniae strain SP49 chromosome, complete genome	1 crisprs	DEDDh,cas3,DinG,RT	0	0	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018136_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018136_1

172003-172098

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018136_1

>merge|NZ_CP018136|1|172003-172098|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>NZ_CP018136|1|1|172003-172098|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018136.1\|WP_001075102.1\|163942_164866_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP018136.1\|WP_001233694.1\|170174_171086_-\|DUF4097-domain-containing-protein	unknown	unknown	gnl\|CDD\|372574
NZ_CP018136.1\|WP_000808453.1\|169048_170113_-\|membrane-protein	unknown	unknown	gnl\|CDD\|370966
NZ_CP018136.1\|WP_000096193.1\|173347_174505_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
NZ_CP018136.1\|WP_073176643.1\|172123_173290_-\|CynX/NimT-family-MFS-transporter	unknown	unknown	gnl\|CDD\|225365
NZ_CP018136.1\|WP_001030029.1\|166870_167857_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
NZ_CP018136.1\|WP_001230166.1\|180703_180991_+\|lactococcin-972-family-bacteriocin	unknown	unknown	gnl\|CDD\|273735
NZ_CP018136.1\|WP_000800407.1\|165123_166599_+\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
NZ_CP018136.1\|WP_000273863.1\|171658_171985_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP018136.1\|WP_000500038.1\|177533_178406_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP018136.1\|WP_000714582.1\|162999_163929_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NZ_CP018136.1\|WP_001035702.1\|174546_176397_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP018136.1\|WP_000198687.1\|171078_171672_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
NZ_CP018136.1\|WP_000836444.1\|179327_179900_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NZ_CP018136.1\|WP_000838912.1\|178414_179086_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NZ_CP018136.1\|WP_001818684.1\|162245_162506_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018136.1\|WP_001810745.1\|162459_162681_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018136.1\|WP_001189283.1\|179952_180273_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018136.1\|WP_000724268.1\|181042_183151_+\|bacteriocin-associated-integral-membrane-family-protein	unknown	unknown	gnl\|CDD\|273736
NZ_CP018136.1\|WP_000200892.1\|176879_177512_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319798

Protein	Function_ID	Function_description	E-value
NZ_CP018136.1\|WP_001233694.1\|170174_171086_-\|DUF4097-domain-containing-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	1.26223e-39
NZ_CP018136.1\|WP_000808453.1\|169048_170113_-\|membrane-protein	gnl\|CDD\|370966	pfam10310, DUF5427, Family of unknown function (DUF5427). This is a domain of unknown function. Family members found in Saccharomyces cerevisiae, are synthetic lethal with genes involved in maintenance of telomere capping. However, experimental evidence is yet to verify the exact function of family members and the domain.	8.96536e-06
NZ_CP018136.1\|WP_000096193.1\|173347_174505_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	5.52043e-109
NZ_CP018136.1\|WP_073176643.1\|172123_173290_-\|CynX/NimT-family-MFS-transporter	gnl\|CDD\|225365	COG2807, CynX, Cyanate permease [Inorganic ion transport and metabolism].	5.53975e-126
NZ_CP018136.1\|WP_001030029.1\|166870_167857_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
NZ_CP018136.1\|WP_001230166.1\|180703_180991_+\|lactococcin-972-family-bacteriocin	gnl\|CDD\|273735	TIGR01653, hypothetical_protein, bacteriocin, lactococcin 972 family. This model represents bacteriocins related to lactococcin 972. Members tend to be found in association with a seven transmembrane putative immunity protein. [Cellular processes, Toxin production and resistance].	2.10536e-25
NZ_CP018136.1\|WP_000800407.1\|165123_166599_+\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.24398e-44
NZ_CP018136.1\|WP_000273863.1\|171658_171985_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	8.86871e-19
NZ_CP018136.1\|WP_000500038.1\|177533_178406_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	2.65225e-106
NZ_CP018136.1\|WP_000714582.1\|162999_163929_+\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	3.01638e-143
NZ_CP018136.1\|WP_001035702.1\|174546_176397_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP018136.1\|WP_000198687.1\|171078_171672_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	2.84602e-63
NZ_CP018136.1\|WP_000836444.1\|179327_179900_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	5.74081e-13
NZ_CP018136.1\|WP_000838912.1\|178414_179086_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.1908e-89
NZ_CP018136.1\|WP_001075102.1\|163942_164866_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.04007e-69
NZ_CP018136.1\|WP_000724268.1\|181042_183151_+\|bacteriocin-associated-integral-membrane-family-protein	gnl\|CDD\|273736	TIGR01654, unnamed_protein_product, bacteriocin-associated integral membrane (putative immunity) protein. This model represents a family of integral membrane proteins, most of which are about 650 residues in size and predicted to span the membrane seven times. Nearly half of the members of this family are found in association with a member of the lactococcin 972 family of bacteriocins (TIGR01653). Others may be associated with uncharacterized proteins that may also act as bacteriocins. Although this protein is suggested to be an immunity protein, and the bacteriocin is suggested to be exported by a Sec-dependent process, the role of this protein is unclear. [Cellular processes, Toxin production and resistance].	0
NZ_CP018136.1\|WP_000200892.1\|176879_177512_-\|HAD-family-hydrolase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.4095e-97

>NZ_CP018136.1|WP_000273863.1|171658_171985_-|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGSIRHDKN
>NZ_CP018136.1|WP_000198687.1|171078_171672_-|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEELIASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA
>NZ_CP018136.1|WP_001233694.1|170174_171086_-|DUF4097-domain-containing-protein
MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVYDSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAENIQVHGKVELTAKDYLRIILDQKENQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR
>NZ_CP018136.1|WP_000808453.1|169048_170113_-|membrane-protein
MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEDSEARTEIEEKKASNSTEEEPDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLTLFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>NZ_CP018136.1|WP_001030029.1|166870_167857_+|rhodanese-related-sulfurtransferase
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
>NZ_CP018136.1|WP_000800407.1|165123_166599_+|DUF3502-domain-containing-protein
MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK
>NZ_CP018136.1|WP_001075102.1|163942_164866_+|carbohydrate-ABC-transporter-permease
MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVFVIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE
>NZ_CP018136.1|WP_000714582.1|162999_163929_+|sugar-ABC-transporter-permease
MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF
>NZ_CP018136.1|WP_001810745.1|162459_162681_+|hypothetical-protein
MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLFLADEKGSEHTEAELIDNLKEVIAKLKANA
>NZ_CP018136.1|WP_001818684.1|162245_162506_+|hypothetical-protein
MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAIASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK
>NZ_CP018136.1|WP_073176643.1|172123_173290_-|CynX/NimT-family-MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQVNQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL
>NZ_CP018136.1|WP_000096193.1|173347_174505_+|glycosyltransferase-family-2-protein
MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML
>NZ_CP018136.1|WP_001035702.1|174546_176397_+|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>NZ_CP018136.1|WP_000200892.1|176879_177512_-|HAD-family-hydrolase
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>NZ_CP018136.1|WP_000500038.1|177533_178406_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>NZ_CP018136.1|WP_000838912.1|178414_179086_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>NZ_CP018136.1|WP_000836444.1|179327_179900_+|LysM-peptidoglycan-binding-domain-containing-protein
MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETVSAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY
>NZ_CP018136.1|WP_001189283.1|179952_180273_-|hypothetical-protein
MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQPKKL
>NZ_CP018136.1|WP_001230166.1|180703_180991_+|lactococcin-972-family-bacteriocin
MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFGYSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTVMEYFYGFE
>NZ_CP018136.1|WP_000724268.1|181042_183151_+|bacteriocin-associated-integral-membrane-family-protein
MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDLYLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLDFTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEMDKDRIVQKWSDFFKIDQATVLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQPMMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPMLWLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTALLIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFYQDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTGIKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFPYSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKLSDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRDIITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVLGLASRMEKRSLVELLKGGIL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4185 : 105026

123

Streptococcus_phage(93.69%)

holin,capsid,tRNA,head,protease,terminase,portal,tail,integrase,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163933.1\|4185_4755_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000258080.1\|4755_8265_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_001234978.1\|8322_8589_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_000041909.1\|8581_8950_+	septum formation initiator family protein	NA	NA	NA	NA
WP_001224749.1\|9069_10338_+	serine hydrolase	NA	NA	NA	NA
WP_001208988.1\|10334_11612_+\|tRNA	tRNA lysidine(34) synthetase TilS	A7K9Y8	Acanthocystis_turfacea_chlorella_virus	2.5e-06	24.1
WP_000892184.1\|11615_12158_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	2.7e-10	28.9
WP_000744557.1\|12173_14132_+\|protease	ATP-dependent zinc metalloprotease FtsH	H8ZJI5	Ostreococcus_tauri_virus	3.2e-109	45.8
WP_000588897.1\|14253_14733_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_000939545.1\|21538_21775_+	hypothetical protein	NA	NA	NA	NA
WP_000205044.1\|22005_23292_+	adenylosuccinate synthase	L7Y4J5	Megavirus	2.7e-72	37.1
WP_000876726.1\|23534_24683_-\|integrase	site-specific integrase	A0A1S5S8M0	Streptococcus_phage	1.6e-217	100.0
WP_073176615.1\|24857_25685_-	restriction endonuclease	A0A1S5S8D3	Streptococcus_phage	1.9e-124	96.7
WP_000170933.1\|25722_26103_-	ImmA/IrrE family metallo-endopeptidase	A0A1S5S9P5	Streptococcus_phage	1.5e-68	100.0
WP_000285962.1\|26115_26379_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5S8E8	Streptococcus_phage	1.2e-43	100.0
WP_000156422.1\|26378_26612_-	hypothetical protein	A0A1S5S8D5	Streptococcus_phage	4.7e-36	100.0
WP_000495824.1\|26611_26980_-	helix-turn-helix transcriptional regulator	A0A1S5S8C4	Streptococcus_phage	3.2e-63	100.0
WP_000842471.1\|27285_27768_-	hypothetical protein	A0A1S5S9P0	Streptococcus_phage	8.4e-80	100.0
WP_000032099.1\|27822_28026_+	transcriptional regulator	A0A1S5SAW4	Streptococcus_phage	9.1e-28	100.0
WP_001057654.1\|28042_28240_+	hypothetical protein	A0A1S5SEL5	Streptococcus_phage	3.6e-29	100.0
WP_001004503.1\|28250_28412_+	hypothetical protein	A0A1S5S8H5	Streptococcus_phage	4.5e-22	100.0
WP_000456433.1\|28406_28832_-	hypothetical protein	A0A1S5S8M8	Streptococcus_phage	2.1e-37	100.0
WP_061752465.1\|28885_29596_+	ORF6C domain-containing protein	A0A1S5S9F1	Streptococcus_phage	1.2e-130	98.3
WP_000370958.1\|29608_29866_+	hypothetical protein	A0A1S5SFD5	Streptococcus_phage	1.2e-43	100.0
WP_000462830.1\|29951_30272_+	hypothetical protein	A0A1S5SAN6	Streptococcus_phage	1.9e-48	100.0
WP_000391813.1\|30287_30584_+	hypothetical protein	A0A1S5SDE3	Streptococcus_phage	6.2e-49	100.0
WP_001289771.1\|30576_31383_+	phage replisome organizer N-terminal domain-containing protein	A0A1S5SEQ1	Streptococcus_phage	6.5e-125	100.0
WP_000538418.1\|31370_31529_+	hypothetical protein	A0A1S5SEV3	Streptococcus_phage	2.8e-24	100.0
WP_050099386.1\|31522_32293_+	ATP-binding protein	A0A1S5SF44	Streptococcus_phage	8.9e-140	99.6
WP_050079583.1\|32307_32502_+	hypothetical protein	A0A1S5S901	Streptococcus_phage	1.6e-29	100.0
WP_050153794.1\|32501_32729_+	hypothetical protein	A0A1S5S904	Streptococcus_phage	2.3e-40	100.0
WP_000233201.1\|32781_32946_+	hypothetical protein	A0A141E182	Streptococcus_phage	1.4e-23	100.0
WP_050153793.1\|32935_33145_+	hypothetical protein	A0A1S5S965	Streptococcus_phage	8.5e-29	100.0
WP_192929472.1\|33116_33446_+	hypothetical protein	E8ZE19	Streptococcus_phage	1.6e-58	96.3
WP_033630928.1\|33435_33939_+	DUF1642 domain-containing protein	A0A1S5SFI7	Streptococcus_phage	9.4e-90	94.6
WP_000194861.1\|33938_34226_+	hypothetical protein	A0A1S5S9Q8	Streptococcus_phage	1.7e-48	100.0
WP_033630929.1\|34225_34687_+	methyltransferase domain-containing protein	A0A1S5S9R6	Streptococcus_phage	5.6e-89	99.3
WP_033630942.1\|34967_35453_+	MazG-like family protein	A0A1S5S9S3	Streptococcus_phage	9.1e-90	100.0
WP_033630930.1\|35449_35848_+	hypothetical protein	A0A1S5S9X0	Streptococcus_phage	9.4e-69	93.5
WP_000736387.1\|35984_36386_+	transcriptional activator	A0A1S5S9L6	Streptococcus_phage	8.1e-68	100.0
WP_000397549.1\|36576_37119_+\|integrase	site-specific integrase	A0A1S5SEW4	Streptococcus_phage	1.4e-99	100.0
WP_054388092.1\|37283_37475_+	hypothetical protein	A0A1S5S8H4	Streptococcus_phage	6.6e-28	95.2
WP_000282422.1\|37594_37915_+	HNH endonuclease	A0A1S5SFJ3	Streptococcus_phage	2.7e-58	100.0
WP_061476800.1\|38052_38445_+\|terminase	P27 family phage terminase small subunit	A0A1S5SEN5	Streptococcus_phage	1.8e-64	97.7
WP_061476797.1\|38437_40168_+\|terminase	terminase large subunit	A0A1S5S9S5	Streptococcus_phage	0.0e+00	99.7
WP_001002923.1\|40175_40394_+	hypothetical protein	A0A1S5SEK2	Streptococcus_phage	1.3e-32	100.0
WP_050218367.1\|40411_41614_+\|portal	phage portal protein	A0A1S5S8H6	Streptococcus_phage	2.6e-226	99.8
WP_001172115.1\|41597_42173_+\|head,protease	HK97 family phage prohead protease	A0A1S5SEX0	Streptococcus_phage	2.2e-103	100.0
WP_033630932.1\|42169_43342_+\|capsid	phage major capsid protein	A0A141E0N4	Streptococcus_phage	2.5e-202	100.0
WP_000120767.1\|43353_43644_+	hypothetical protein	A0A1S5S8Q9	Streptococcus_phage	7.7e-36	100.0
WP_000371962.1\|43646_43928_+\|head,tail	phage head-tail connector protein	A0A1S5S8H0	Streptococcus_phage	1.8e-45	100.0
WP_000267061.1\|43914_44214_+\|head	phage head closure protein	A0A1S5S8I2	Streptococcus_phage	3.7e-49	100.0
WP_000063886.1\|44210_44558_+	HK97 gp10 family phage protein	A0A1S5SEL8	Streptococcus_phage	8.8e-47	100.0
WP_000777003.1\|44554_44878_+	hypothetical protein	A0A1S5SEP5	Streptococcus_phage	3.5e-53	100.0
WP_000191278.1\|44889_45468_+	hypothetical protein	A0A1S5S8L9	Streptococcus_phage	2.6e-107	100.0
WP_024478843.1\|45479_45899_+	hypothetical protein	A0A1S5S9L8	Streptococcus_phage	1.9e-72	99.3
WP_061749540.1\|46175_48935_+	hypothetical protein	A0A1S5SB25	Streptococcus_phage	1.7e-281	100.0
WP_061752457.1\|48931_49654_+	hypothetical protein	A0A1S5S9H2	Streptococcus_phage	2.2e-132	97.9
WP_078375700.1\|49654_57781_+\|tail	tail fiber domain-containing protein	A0A1S5S9I2	Streptococcus_phage	0.0e+00	97.9
WP_001091119.1\|57875_58079_+	hypothetical protein	X2KU40	Streptococcus_phage	1.1e-25	100.0
WP_000852244.1\|58081_58432_+	hypothetical protein	A0A1S5SFA0	Streptococcus_phage	3.6e-64	100.0
WP_001165344.1\|58441_58858_+\|holin	phage holin family protein	A0A1S5SCE8	Streptococcus_phage	1.9e-67	100.0
WP_050247604.1\|58861_59194_+\|holin	phage holin	A0A1S5SF85	Streptococcus_phage	4.3e-51	100.0
WP_073176617.1\|59197_60154_+	N-acetylmuramoyl-L-alanine amidase LytA	A0A1S5S8S6	Streptococcus_phage	3.3e-144	99.7
WP_001233269.1\|60291_60471_-	hypothetical protein	Q3BLW4	Phage_SK137	2.1e-23	96.6
WP_001030863.1\|60612_60762_-	hypothetical protein	C5J952	Streptococcus_phage	9.1e-17	95.9
WP_000291875.1\|61043_61511_+	nucleoside deaminase	NA	NA	NA	NA
WP_000266837.1\|61719_62862_-\|integrase	site-specific integrase	U4KJ82	Streptococcus_phage	3.4e-212	99.7
WP_001020945.1\|62980_63331_-	hypothetical protein	Q9MBY8	Streptococcus_phage	7.3e-57	100.0
WP_000136430.1\|63344_63725_-	ImmA/IrrE family metallo-endopeptidase	A0A1S5SE39	Streptococcus_phage	4.2e-66	100.0
WP_000153672.1\|63746_64103_-	helix-turn-helix transcriptional regulator	A0A1S5SDR1	Streptococcus_phage	4.2e-60	100.0
WP_000638668.1\|64378_64564_+	helix-turn-helix transcriptional regulator	A0A1S5SDM7	Streptococcus_phage	1.0e-25	98.4
WP_073176619.1\|64565_65264_+	phage antirepressor KilAC domain-containing protein	A0A1S5SDI0	Streptococcus_phage	4.9e-129	99.6
WP_000046504.1\|65328_65595_+	hypothetical protein	A0A1S5SDD2	Streptococcus_phage	5.9e-43	100.0
WP_073176621.1\|65939_66206_+	helix-turn-helix domain-containing protein	A0A1S5SBR3	Streptococcus_phage	3.5e-43	98.9
WP_000450966.1\|66437_66704_+	hypothetical protein	A0A1S5SE97	Streptococcus_phage	1.1e-41	100.0
WP_001134281.1\|66786_67239_+	hypothetical protein	A0A1S5S8P1	Streptococcus_phage	6.5e-82	100.0
WP_000774580.1\|67244_67946_+	ERF family protein	A0A1S5SEM6	Streptococcus_phage	1.5e-117	100.0
WP_073176622.1\|67948_68941_+	DUF1351 domain-containing protein	A0A1S5SEK4	Streptococcus_phage	2.8e-178	99.4
WP_001203349.1\|68962_69139_+	hypothetical protein	A0A1S5SE71	Streptococcus_phage	4.8e-25	100.0
WP_050240764.1\|69128_69704_+	single-stranded DNA-binding protein	A0A1S5S8T8	Streptococcus_phage	8.5e-87	97.9
WP_000161128.1\|69770_69974_+	hypothetical protein	U4KJ79	Streptococcus_phage	4.4e-30	100.0
WP_050240765.1\|70109_70859_+	site-specific DNA-methyltransferase	A0A1S5SFX1	Streptococcus_phage	3.4e-144	100.0
WP_000358622.1\|70873_71308_+	hypothetical protein	A0A1S5SG21	Streptococcus_phage	7.4e-67	100.0
WP_050240766.1\|71309_72047_+	hypothetical protein	Q0R597	Streptococcus_phage	6.1e-130	96.7
WP_001286809.1\|72063_72276_+	hypothetical protein	A0A1S5SEA6	Streptococcus_phage	1.7e-32	100.0
WP_000667209.1\|72286_72688_+	hypothetical protein	U4KJA0	Streptococcus_phage	1.9e-72	100.0
WP_000573750.1\|72689_72896_+	hypothetical protein	A0A1S5SDU5	Streptococcus_phage	1.1e-31	100.0
WP_192929473.1\|72944_73262_+	hypothetical protein	A0A141DZV2	Streptococcus_phage	2.8e-55	95.2
WP_050258448.1\|73759_74131_+	hypothetical protein	A0A1S5SFV7	Streptococcus_phage	1.5e-47	96.7
WP_050258447.1\|74151_74445_+	hypothetical protein	A0A1S5S8M6	Streptococcus_phage	4.0e-40	85.6
WP_000162611.1\|74444_74837_+	hypothetical protein	A0A1S5SED1	Streptococcus_phage	7.1e-69	100.0
WP_000425573.1\|74902_75997_+	DUF4417 domain-containing protein	A0A1S5SEG1	Streptococcus_phage	1.1e-202	100.0
WP_073176625.1\|75977_76724_+	hypothetical protein	A0A1S5SDN7	Streptococcus_phage	3.7e-135	99.6
WP_001136855.1\|76927_77383_+	hypothetical protein	A0A1C9LX59	Streptococcus_phage	5.0e-74	100.0
WP_000143806.1\|77372_78683_+\|terminase	PBSX family phage terminase large subunit	U4KJA9	Streptococcus_phage	1.8e-257	100.0
WP_023396076.1\|78695_80264_+\|portal	phage portal protein	Q0R582	Streptococcus_phage	4.1e-301	99.8
WP_073176627.1\|80250_80451_+	hypothetical protein	A0A1S5SEA5	Streptococcus_phage	8.2e-21	100.0
WP_073176629.1\|80493_81645_+\|capsid	phage minor capsid protein	Q0R580	Streptococcus_phage	1.9e-218	99.7
WP_000896122.1\|81783_82347_+	phage scaffolding protein	A0A1S5SEM4	Streptococcus_phage	9.9e-80	100.0
WP_001139820.1\|82364_83246_+	hypothetical protein	A0A1S5SCM2	Streptococcus_phage	2.1e-161	100.0
WP_001240344.1\|83256_83490_+	hypothetical protein	A0A1S5SEE1	Streptococcus_phage	6.8e-35	100.0
WP_000221834.1\|83532_83925_+	hypothetical protein	A0A1C9LXX3	Streptococcus_phage	1.2e-63	100.0
WP_000565932.1\|83914_84286_+\|capsid	phage capsid protein	A0A1S5SDX7	Streptococcus_phage	8.0e-54	100.0
WP_001017357.1\|84285_84630_+	hypothetical protein	A0A141DZI7	Streptococcus_phage	2.9e-58	100.0
WP_001208881.1\|84629_85037_+\|capsid	phage capsid protein	A0A1S5SEE3	Streptococcus_phage	3.2e-72	100.0
WP_023396079.1\|85033_85483_+	hypothetical protein	A0A1S5SEC5	Streptococcus_phage	8.4e-82	100.0
WP_023396080.1\|85547_86036_+	hypothetical protein	U4KJ74	Streptococcus_phage	8.3e-83	99.4
WP_078375701.1\|86048_86618_+	hypothetical protein	U4KJ63	Streptococcus_phage	3.2e-102	99.5
WP_073176631.1\|86610_89913_+	tape measure protein	A0A1S5SDZ2	Streptococcus_phage	0.0e+00	95.4
WP_000161549.1\|89909_91424_+\|tail	phage tail family protein	A0A1S5SEJ1	Streptococcus_phage	2.0e-300	100.0
WP_073176633.1\|91425_95991_+\|tail	phage tail protein	A0A1S5SFY2	Streptococcus_phage	0.0e+00	99.3
WP_024475385.1\|96001_98080_+	hypothetical protein	A0A141DZH9	Streptococcus_phage	0.0e+00	100.0
WP_000922100.1\|98139_98403_+	hypothetical protein	A0A1S5SEN3	Streptococcus_phage	1.8e-39	100.0
WP_000687457.1\|98412_98829_+\|holin	phage holin family protein	A0A1S5SEC7	Streptococcus_phage	4.9e-68	100.0
WP_050247604.1\|98832_99165_+\|holin	phage holin	A0A1S5SF85	Streptococcus_phage	4.3e-51	100.0
WP_073176617.1\|99168_100125_+	N-acetylmuramoyl-L-alanine amidase LytA	A0A1S5S8S6	Streptococcus_phage	3.3e-144	99.7
WP_000701992.1\|100408_100852_+	dUTP diphosphatase	Q2WG49	Clostridium_botulinum_D_phage	2.1e-29	47.3
WP_001836031.1\|100853_101369_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_073176637.1\|101382_102744_+	DNA repair protein RadA	NA	NA	NA	NA
WP_001809263.1\|102816_103314_+	carbonic anhydrase	NA	NA	NA	NA
WP_000272771.1\|103334_103679_+	hypothetical protein	NA	NA	NA	NA
WP_088778796.1\|103675_105026_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.9e-62	50.9

DBSCAN-SWA_2

117641 : 129097

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050123218.1\|117641_119795_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	5.5e-46	28.2
WP_000801620.1\|119807_121157_+	HlyD family secretion protein	NA	NA	NA	NA
WP_000043300.1\|121326_122034_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	1.8e-41	39.2
WP_000361192.1\|122235_125961_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.8e-37	25.6
WP_000220627.1\|126053_127496_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.8e-54	35.1
WP_000182575.1\|127532_128555_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	1.2e-64	43.9
WP_000717501.1\|128551_129097_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.7e-24	35.0

DBSCAN-SWA_3

180703 : 204870

Planktothrix_phage(50.0%)

bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001230166.1\|180703_180991_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000724268.1\|181042_183151_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000571330.1\|183147_183789_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.3e-23	34.8
WP_001038474.1\|183995_184802_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_000031929.1\|184818_185046_+	argininosuccinate synthase	NA	NA	NA	NA
WP_000252931.1\|185076_185238_+	argininosuccinate synthase	NA	NA	NA	NA
WP_001268152.1\|185423_186287_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000424429.1\|186923_187295_+\|bacteriocin	SPH_0218 family bacteriocin-like peptide	NA	NA	NA	NA
WP_001857889.1\|187302_187515_+	hypothetical protein	NA	NA	NA	NA
WP_001855840.1\|188395_189454_+	hypothetical protein	NA	NA	NA	NA
WP_001857891.1\|189635_190592_+	hypothetical protein	NA	NA	NA	NA
WP_000424414.1\|190968_191343_+\|bacteriocin	SPH_0224 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000619754.1\|191550_192453_+	hypothetical protein	NA	NA	NA	NA
WP_180372847.1\|192508_192841_+	argininosuccinate lyase	NA	NA	NA	NA
WP_000072897.1\|192837_193566_+	hypothetical protein	NA	NA	NA	NA
WP_000770312.1\|194701_194941_+	hypothetical protein	NA	NA	NA	NA
WP_001811652.1\|194925_195204_+	hypothetical protein	M1Q0Z8	Streptococcus_phage	1.9e-20	50.5
WP_061696410.1\|195489_197379_+	pneumococcal surface protein A	NA	NA	NA	NA
WP_050198263.1\|197779_198901_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000193638.1\|199041_199497_+	NUDIX hydrolase	NA	NA	NA	NA
WP_000220953.1\|199506_201420_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_000331980.1\|201798_203478_-	ribonuclease J	NA	NA	NA	NA
WP_000639579.1\|203479_203713_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_000282479.1\|203992_204208_+	hypothetical protein	NA	NA	NA	NA
WP_000974047.1\|204530_204683_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibB	NA	NA	NA	NA
WP_000180805.1\|204684_204870_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibA	NA	NA	NA	NA

DBSCAN-SWA_4

252066 : 258790

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000424665.1\|252066_252693_+	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	2.1e-30	40.8
WP_000141100.1\|253064_253517_+	hypothetical protein	NA	NA	NA	NA
WP_000174331.1\|253513_253714_+	hypothetical protein	NA	NA	NA	NA
WP_001003774.1\|253715_253931_+	hypothetical protein	NA	NA	NA	NA
WP_000058832.1\|253927_254269_+	hypothetical protein	NA	NA	NA	NA
WP_000492137.1\|254261_254543_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	7.9e-30	67.8
WP_000158192.1\|254677_255544_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	8.2e-126	75.0
WP_000434361.1\|255596_257066_+	DNA primase family protein	Q9AZI5	Lactococcus_phage	8.1e-65	35.2
WP_000865230.1\|257428_257596_+	hypothetical protein	NA	NA	NA	NA
WP_000173130.1\|257679_258210_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	2.8e-36	48.7
WP_000811078.1\|258280_258790_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	5.8e-47	53.9

DBSCAN-SWA_5

499130 : 554049

Klosneuvirus(20.0%)

bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001810089.1\|499130_499301_-\|transposase	transposase	NA	NA	NA	NA
WP_073176709.1\|500062_500320_+	PTS mannose transporter subunit IIA	NA	NA	NA	NA
WP_001838249.1\|500445_501885_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000691685.1\|501888_503238_-	Trk system potassium transporter TrkA	NA	NA	NA	NA
WP_001063601.1\|503426_504275_+	S-adenosyl-l-methionine hydroxide adenosyltransferase family protein	NA	NA	NA	NA
WP_000403162.1\|504289_504838_+	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_057532045.1\|504907_505093_+	hypothetical protein	NA	NA	NA	NA
WP_000656549.1\|505203_506886_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-19	34.4
WP_001148103.1\|506870_507701_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000181373.1\|507893_508397_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_000185828.1\|508849_509413_+	ECF transporter S component	NA	NA	NA	NA
WP_000678709.1\|509426_510053_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000867297.1\|510080_510470_+	hypothetical protein	NA	NA	NA	NA
WP_000333646.1\|510474_510924_+	N-acetyltransferase	NA	NA	NA	NA
WP_000418402.1\|511051_511639_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_000105242.1\|512028_513636_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.9e-142	47.0
WP_000026645.1\|514194_515826_-	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_000795169.1\|516118_521098_+	bacterial Ig-like domain-containing protein	NA	NA	NA	NA
WP_001096743.1\|521187_522384_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_000119888.1\|522519_523047_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_000659547.1\|523123_523480_+	transcriptional repressor GlnR	NA	NA	NA	NA
WP_001122900.1\|523516_524863_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_001808898.1\|524952_525072_-	hypothetical protein	NA	NA	NA	NA
WP_001220759.1\|525637_526918_+	restriction endonuclease subunit S	A0A1V0SKS6	Klosneuvirus	6.9e-12	29.2
WP_000651177.1\|526974_527772_+	tyrosine-type DNA invertase PsrA	A0A0H4TI16	Erysipelothrix_phage	1.3e-21	28.7
WP_000240090.1\|527782_528391_+	restriction endonuclease subunit S	A0A1V0SLK8	Klosneuvirus	3.9e-13	30.1
WP_050285397.1\|528338_529904_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000029055.1\|529903_531367_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_000229101.1\|531379_533713_-	DEAD/DEAH box helicase family protein	Q5YA94	Bacillus_phage	5.8e-25	27.6
WP_000550235.1\|534392_534830_+	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_000255781.1\|534993_536028_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_000046035.1\|536054_536579_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_000034662.1\|537058_538882_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.3e-133	47.2
WP_000114422.1\|538883_539240_+	hypothetical protein	NA	NA	NA	NA
WP_001066301.1\|539641_540778_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	1.7e-22	31.0
WP_000777760.1\|541099_541387_-	hypothetical protein	NA	NA	NA	NA
WP_001278301.1\|541396_541807_-	HIT family protein	B5LJ12	Mycobacterium_phage	3.4e-05	31.6
WP_000889919.1\|541874_542606_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.1e-25	28.6
WP_073176713.1\|542602_543652_+	ABC transporter permease	NA	NA	NA	NA
WP_000132572.1\|543819_544149_-	hypothetical protein	NA	NA	NA	NA
WP_000682126.1\|544424_544763_+	response regulator transcription factor	NA	NA	NA	NA
WP_001219143.1\|544767_545505_+	response regulator transcription factor	NA	NA	NA	NA
WP_073176715.1\|545518_546859_+	sensor histidine kinase	NA	NA	NA	NA
WP_000358814.1\|546903_547059_-	quorum-sensing system pheromone BlpC	NA	NA	NA	NA
WP_001069098.1\|547115_548477_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_001093268.1\|550815_551046_+\|bacteriocin	bacteriocin-like peptide BlpU	NA	NA	NA	NA
WP_000346298.1\|551048_551168_+	hypothetical protein	NA	NA	NA	NA
WP_000727118.1\|551464_551629_+	hypothetical protein	NA	NA	NA	NA
WP_000846944.1\|551625_552030_+	hypothetical protein	NA	NA	NA	NA
WP_000379879.1\|553182_553437_+\|bacteriocin	two-peptide bacteriocin subunit BlpM	NA	NA	NA	NA
WP_001099492.1\|553452_553656_+\|bacteriocin	two-peptide bacteriocin subunit BlpN	NA	NA	NA	NA
WP_001813641.1\|553899_554049_+\|bacteriocin	bacteriocin-like peptide BlpO	NA	NA	NA	NA

DBSCAN-SWA_6

915501 : 925908

Streptococcus_phage(70.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001025704.1\|915501_916410_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	3.1e-06	27.7
WP_000745389.1\|916406_916868_+	signal peptidase II	NA	NA	NA	NA
WP_000403195.1\|916857_917745_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.3e-09	28.0
WP_000728255.1\|917747_919643_+\|holin	phosphorylcholine esterase CbpE	Q332B9	Clostridium_botulinum_C_phage	1.9e-10	24.1
WP_073176995.1\|919722_920853_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	8.5e-115	58.7
WP_000254677.1\|920862_922125_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.1e-139	64.5
WP_073176998.1\|922128_922926_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.2e-59	50.6
WP_000033362.1\|923144_923783_+	dTMP kinase	M1PSC7	Streptococcus_phage	9.8e-76	68.1
WP_000806708.1\|923779_924670_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.4e-73	51.4
WP_000358228.1\|924709_925027_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
WP_001166873.1\|925029_925908_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.9e-115	75.7

DBSCAN-SWA_7

1199433 : 1238311

Indivirus(20.0%)

holin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000411210.1\|1199433_1200303_-\|holin	choline kinase LicA	NA	NA	NA	NA
WP_000609894.1\|1200319_1201342_-	alcohol dehydrogenase catalytic domain-containing protein	NA	NA	NA	NA
WP_000638504.1\|1201346_1202054_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_044814531.1\|1202389_1203877_+	type IV teichoic acid flippase TacF	NA	NA	NA	NA
WP_000811993.1\|1203886_1204690_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	9.0e-10	32.9
WP_001199653.1\|1204691_1205501_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	9.1e-10	30.3
WP_001126435.1\|1205774_1208951_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_000166701.1\|1209263_1210343_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.3e-59	35.9
WP_001293845.1\|1210392_1211316_-	aspartate carbamoyltransferase catalytic subunit	M1HGA5	Paramecium_bursaria_Chlorella_virus	8.7e-25	31.7
WP_000850024.1\|1211334_1211856_-	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_000244451.1\|1212066_1212696_-	endonuclease III	NA	NA	NA	NA
WP_023396323.1\|1212695_1213238_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_000389597.1\|1213407_1213725_+	hypothetical protein	NA	NA	NA	NA
WP_000558897.1\|1213963_1215523_+	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	9.3e-11	27.5
WP_050072400.1\|1215566_1216466_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_000219847.1\|1216467_1217028_-	LemA family protein	NA	NA	NA	NA
WP_000802934.1\|1217121_1217835_+	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_000808288.1\|1218235_1219519_+	uracil transporter	Q9KX94	Enterobacteria_phage	4.0e-60	35.3
WP_000863628.1\|1219713_1221285_-	signal recognition particle protein	NA	NA	NA	NA
WP_000402071.1\|1221296_1221629_-	putative DNA-binding protein	NA	NA	NA	NA
WP_023396325.1\|1221719_1222097_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_001003501.1\|1222168_1223473_+	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	1.7e-26	30.2
WP_000023518.1\|1223485_1224292_+	sugar-phosphatase	NA	NA	NA	NA
WP_001009001.1\|1224334_1225333_+	SAP domain-containing protein	NA	NA	NA	NA
WP_001068669.1\|1225612_1225960_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000237416.1\|1226078_1226408_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.3e-10	37.8
WP_000712098.1\|1226401_1226776_-	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_000362435.1\|1226772_1227039_-	chorismate mutase	NA	NA	NA	NA
WP_001162129.1\|1227154_1227598_-	flavodoxin	NA	NA	NA	NA
WP_000401775.1\|1227701_1228637_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_001808393.1\|1228690_1228975_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_001835775.1\|1229031_1229520_-	hypothetical protein	NA	NA	NA	NA
WP_000199575.1\|1231266_1232613_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_000436627.1\|1232691_1233948_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	9.5e-224	91.9
WP_000711943.1\|1234530_1234701_-	hypothetical protein	NA	NA	NA	NA
WP_088804224.1\|1236960_1238311_+\|transposase	IS3-like element ISSpn4 family transposase	A0A1B1P773	Bacillus_phage	1.8e-63	49.6

DBSCAN-SWA_8

1325480 : 1382163

Streptococcus_phage(20.0%)

holin,bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001090150.1\|1325480_1326509_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_073177112.1\|1327169_1328297_-	G5 domain-containing protein	NA	NA	NA	NA
WP_000835656.1\|1329011_1329563_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000058041.1\|1329960_1330785_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.1e-74	57.5
WP_000283127.1\|1330781_1332242_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.7e-103	43.1
WP_000797183.1\|1332357_1332846_-	hypothetical protein	NA	NA	NA	NA
WP_001107505.1\|1332835_1333045_-	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	4.1e-07	49.1
WP_000773497.1\|1333429_1334158_-	ABC transporter permease	NA	NA	NA	NA
WP_073177114.1\|1334173_1334965_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-22	36.9
WP_001809119.1\|1336373_1336685_-	hypothetical protein	NA	NA	NA	NA
WP_000169086.1\|1336699_1337986_-	U32 family peptidase	Q6DW11	Phage_TP	1.6e-40	31.3
WP_001262531.1\|1338609_1338792_+	ApaLI family restriction endonuclease	NA	NA	NA	NA
WP_078064042.1\|1338801_1339167_+	ApaLI family restriction endonuclease	NA	NA	NA	NA
WP_000065723.1\|1340428_1341991_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.4e-19	32.8
WP_000936188.1\|1342132_1342831_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000071691.1\|1342873_1343770_-	EamA family transporter	NA	NA	NA	NA
WP_000872226.1\|1343778_1344714_-	serine hydrolase	NA	NA	NA	NA
WP_001102216.1\|1344710_1345436_-	CppA family protein	NA	NA	NA	NA
WP_000290644.1\|1345519_1346155_-\|holin	1-alkyl-2-acetylglycerophosphocholine esterase	A0A2K9L661	Tupanvirus	9.6e-07	27.7
WP_000972851.1\|1346156_1346984_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000526286.1\|1347005_1347341_-	hypothetical protein	NA	NA	NA	NA
WP_000929997.1\|1347341_1348058_-	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	1.1e-27	31.6
WP_001272941.1\|1348570_1349182_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
WP_000855735.1\|1349226_1349955_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000272310.1\|1349993_1350905_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	8.5e-89	51.1
WP_000926600.1\|1350970_1351195_-	DUF4059 family protein	NA	NA	NA	NA
WP_000590970.1\|1351272_1352016_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-29	40.5
WP_001103449.1\|1352015_1352816_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000889093.1\|1352973_1353330_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
WP_001170347.1\|1353323_1353854_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.4e-46	54.3
WP_000405832.1\|1353853_1354348_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.9e-42	52.1
WP_000858730.1\|1354482_1354929_+	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_001097986.1\|1354925_1355573_+	hemolysin III family protein	NA	NA	NA	NA
WP_000689945.1\|1355593_1356175_-	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA	NA	NA	NA
WP_000138517.1\|1356175_1357051_-	pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA	NA	NA	NA
WP_000036790.1\|1357202_1358582_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_000175406.1\|1358875_1359799_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_000915928.1\|1359858_1360464_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	2.2e-53	53.7
WP_000673698.1\|1360482_1361727_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	4.9e-55	52.7
WP_000371288.1\|1361842_1362100_-	DUF896 family protein	NA	NA	NA	NA
WP_000164769.1\|1362141_1364178_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_000038764.1\|1364401_1365319_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_000369578.1\|1365512_1366274_-	hypothetical protein	NA	NA	NA	NA
WP_001099672.1\|1366546_1367389_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.2e-51	39.8
WP_001855094.1\|1367502_1368894_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_001842109.1\|1369128_1369506_-\|transposase	PD-(D/E)XK nuclease family transposase	NA	NA	NA	NA
WP_000915911.1\|1369738_1370716_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_000850572.1\|1370712_1371795_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.2e-37	31.3
WP_001040724.1\|1373288_1374485_-	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	7.3e-32	29.6
WP_000348122.1\|1375395_1376265_-	aquaporin family protein	NA	NA	NA	NA
WP_000248971.1\|1376488_1377166_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_001021431.1\|1377123_1378203_-	MucBP domain-containing protein	NA	NA	NA	NA
WP_001842111.1\|1378313_1378568_-	hypothetical protein	NA	NA	NA	NA
WP_000200316.1\|1378907_1379441_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_001811210.1\|1379427_1379643_-\|transposase	transposase	NA	NA	NA	NA
WP_001811209.1\|1379609_1379753_-\|transposase	transposase	NA	NA	NA	NA
WP_000121703.1\|1379986_1381705_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	4.4e-272	83.0
WP_000434644.1\|1381815_1382163_+\|bacteriocin	PedC/BrcD family bacteriocin maturation disulfide isomerase	NA	NA	NA	NA

DBSCAN-SWA_9

1417868 : 1502336

Streptococcus_phage(73.91%)

holin,capsid,tRNA,head,terminase,protease,portal,tail,integrase

attL 1425364:1425396|attR 1506719:1506751

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000390781.1\|1417868_1418618_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_000689600.1\|1418671_1419031_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_151892413.1\|1419032_1420394_-	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	2.6e-25	44.6
WP_000068664.1\|1420728_1420968_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_000609607.1\|1420999_1421470_-	single-stranded DNA-binding protein SsbA	A0A2H4J1H8	uncultured_Caudovirales_phage	2.4e-55	67.7
WP_001151785.1\|1421481_1421772_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_161801414.1\|1421924_1423271_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	6.3e-56	31.2
WP_000565216.1\|1423427_1423652_-	hypothetical protein	NA	NA	NA	NA
WP_000777792.1\|1423644_1424832_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000747257.1\|1424828_1425317_-	DUF5590 domain-containing protein	NA	NA	NA	NA
1425364:1425396	attL	NA	NA	NA	NA
WP_000039647.1\|1425637_1426186_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_050198442.1\|1426422_1432023_-	YSIRK signal domain/LPXTG anchor domain surface protein	A0A2I2L3G6	Orpheovirus	1.7e-09	35.7
WP_001245190.1\|1432238_1433723_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000697775.1\|1433773_1434502_-	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	2.6e-40	39.0
WP_000508269.1\|1434580_1434745_-	YczI family protein	NA	NA	NA	NA
WP_000822863.1\|1434810_1436406_-	hypothetical protein	NA	NA	NA	NA
WP_000412220.1\|1436417_1436828_-	peptide deformylase	A0A2I7R224	Vibrio_phage	1.3e-09	32.2
WP_001277403.1\|1436943_1437735_-	glutathione-dependent disulfide-bond oxidoreductase	NA	NA	NA	NA
WP_000032458.1\|1437747_1440444_-	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	8.1e-71	28.6
WP_000813916.1\|1440747_1441932_+	CDF family manganese efflux transporter MntE	NA	NA	NA	NA
WP_001279133.1\|1442074_1443946_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.0e-56	31.1
WP_001138814.1\|1443942_1445127_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	2.0e-37	45.5
WP_000027902.1\|1445138_1445906_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_000762070.1\|1446182_1447031_-	DegV family protein	NA	NA	NA	NA
WP_001050086.1\|1447032_1447407_-	DUF1149 family protein	NA	NA	NA	NA
WP_000521410.1\|1447480_1448833_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_000742290.1\|1448856_1449636_-	YbbR-like domain-containing protein	NA	NA	NA	NA
WP_001011058.1\|1449622_1450480_-	TIGR00159 family protein	NA	NA	NA	NA
WP_000081003.1\|1450615_1451584_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	2.8e-66	100.0
WP_061367891.1\|1451835_1452792_-	N-acetylmuramoyl-L-alanine amidase family protein	A0A1S5SCM9	Streptococcus_phage	1.6e-143	99.1
WP_001186228.1\|1452795_1453128_-\|holin	phage holin	E8ZDJ3	Streptococcus_phage	3.3e-51	100.0
WP_050142252.1\|1453131_1453548_-\|holin	phage holin family protein	A0A1S5SEC7	Streptococcus_phage	5.4e-67	98.6
WP_000852244.1\|1453557_1453908_-	hypothetical protein	A0A1S5SFA0	Streptococcus_phage	3.6e-64	100.0
WP_001091119.1\|1453910_1454114_-	hypothetical protein	X2KU40	Streptococcus_phage	1.1e-25	100.0
WP_000068031.1\|1462222_1462573_-	hypothetical protein	A0A060QSS8	Streptococcus_phage	3.1e-63	100.0
WP_000212159.1\|1462581_1466235_-	hypothetical protein	A0A1S5SBS7	Streptococcus_phage	0.0e+00	100.0
WP_000478016.1\|1466221_1466572_-	hypothetical protein	A0A1S5S814	Streptococcus_phage	1.2e-56	100.0
WP_001185634.1\|1466610_1466991_-	hypothetical protein	A0A1S5S849	Streptococcus_phage	1.2e-65	100.0
WP_050228844.1\|1466995_1467409_-\|tail	phage tail protein	A0A060QN80	Streptococcus_phage	1.2e-71	100.0
WP_050228845.1\|1467414_1467783_-	hypothetical protein	A0A060QNT4	Streptococcus_phage	1.2e-65	100.0
WP_050228846.1\|1467779_1468295_-	HK97 gp10 family phage protein	A0A141E1X2	Streptococcus_phage	2.4e-88	95.3
WP_000478943.1\|1468269_1468608_-	hypothetical protein	A0A1S5SCH1	Streptococcus_phage	8.6e-47	100.0
WP_000021220.1\|1468588_1468900_-\|head,tail	phage head-tail adapter protein	A0A1S5SES7	Streptococcus_phage	2.5e-48	100.0
WP_000669349.1\|1468901_1469090_-	hypothetical protein	X2L097	Streptococcus_phage	1.1e-27	100.0
WP_000054934.1\|1469079_1469262_-	Rho termination factor N-terminal domain-containing protein	X2KSZ5	Streptococcus_phage	1.2e-23	100.0
WP_000123890.1\|1469273_1470119_-\|capsid	N4-gp56 family major capsid protein	X2KPH5	Streptococcus_phage	5.9e-153	100.0
WP_001288024.1\|1470125_1470710_-	DUF4355 domain-containing protein	X2KU26	Streptococcus_phage	5.6e-86	100.0
WP_000890164.1\|1470926_1471178_-	hypothetical protein	A0A1S5SB84	Streptococcus_phage	4.4e-40	98.8
WP_000877356.1\|1471179_1471425_-	hypothetical protein	A0A141E0I6	Streptococcus_phage	1.2e-42	100.0
WP_000565275.1\|1471467_1471881_-	HD domain-containing protein	A0A060QNR4	Streptococcus_phage	3.2e-67	99.3
WP_000651747.1\|1471877_1472087_-	hypothetical protein	A0A141E1P2	Streptococcus_phage	2.6e-33	100.0
WP_179131855.1\|1472088_1473726_-\|capsid	minor capsid protein	A0A060QST6	Streptococcus_phage	3.8e-297	98.3
WP_000285389.1\|1473634_1475104_-\|portal	phage portal protein	A0A1S5SCF7	Streptococcus_phage	1.2e-278	100.0
WP_050168011.1\|1475115_1476414_-\|terminase	PBSX family phage terminase large subunit	A0A1S5SBQ5	Streptococcus_phage	8.0e-258	99.8
WP_001841119.1\|1476391_1476832_-\|terminase	terminase small subunit	A0A1S5SCD2	Streptococcus_phage	2.0e-75	100.0
WP_050168009.1\|1477389_1477809_-	DUF1492 domain-containing protein	A0A126GGN9	Streptococcus_phage	2.0e-69	100.0
WP_050168005.1\|1477878_1478250_-	hypothetical protein	A0A126GGP7	Streptococcus_phage	8.8e-53	100.0
WP_073177124.1\|1478249_1478567_-	3-dehydroquinate synthase	A0A1S5SDY8	Streptococcus_phage	1.3e-49	94.3
WP_073177126.1\|1478563_1478956_-	hypothetical protein	A0A1S5SGC6	Streptococcus_phage	4.2e-69	96.1
WP_073177129.1\|1479260_1479932_-	DUF1642 domain-containing protein	U4KJ89	Streptococcus_phage	2.0e-127	98.7
WP_050250933.1\|1479933_1480248_-	hypothetical protein	A0A1S5SCT8	Streptococcus_phage	5.0e-57	99.0
WP_000119453.1\|1480398_1480737_-	hypothetical protein	A0A1S5SDI1	Streptococcus_phage	5.6e-62	100.0
WP_001277861.1\|1480733_1480922_-	hypothetical protein	A0A1S5S928	Streptococcus_phage	5.5e-27	100.0
WP_000194862.1\|1480921_1481209_-	hypothetical protein	A0A141E0P3	Streptococcus_phage	7.8e-49	100.0
WP_050202881.1\|1481208_1481733_-	DUF1642 domain-containing protein	A0A1S5SE33	Streptococcus_phage	8.6e-78	83.3
WP_050202882.1\|1481725_1481914_-	hypothetical protein	A0A1S5S997	Streptococcus_phage	3.2e-11	59.7
WP_000233203.1\|1481900_1482068_-	hypothetical protein	A0A1S5SEY3	Streptococcus_phage	5.0e-24	100.0
WP_061753256.1\|1482168_1482477_-	VRR-NUC domain-containing protein	A0A2H4JH82	uncultured_Caudovirales_phage	2.1e-47	92.2
WP_180378733.1\|1482728_1484279_-	DNA primase family protein	A0A2H4JBQ3	uncultured_Caudovirales_phage	5.2e-280	89.7
WP_061753253.1\|1484268_1485066_-	bifunctional DNA primase/polymerase	A0A2H4JBR5	uncultured_Caudovirales_phage	1.8e-135	90.5
WP_061753251.1\|1485069_1485552_-	DUF669 domain-containing protein	A0A2H4JER1	uncultured_Caudovirales_phage	1.2e-78	95.0
WP_073177130.1\|1485557_1486967_-	DEAD/DEAH box helicase	A0A2H4JBQ0	uncultured_Caudovirales_phage	3.4e-246	89.6
WP_061753247.1\|1486923_1487625_-	AAA family ATPase	A0A2H4JI15	uncultured_Caudovirales_phage	3.1e-131	97.4
WP_061753245.1\|1487621_1488098_-	siphovirus Gp157 family protein	A0A2H4JBT9	uncultured_Caudovirales_phage	7.6e-65	81.9
WP_061753243.1\|1488094_1488436_-	hypothetical protein	A0A1S5SA87	Streptococcus_phage	3.4e-51	87.6
WP_050253754.1\|1488570_1488762_-	hypothetical protein	NA	NA	NA	NA
WP_049512772.1\|1488742_1489069_-	hypothetical protein	Q708Q6	Streptococcus_phage	8.4e-15	56.5
WP_049512774.1\|1489138_1489411_-	hypothetical protein	A0A1S5SAL2	Streptococcus_phage	1.1e-41	96.7
WP_055348618.1\|1489641_1490178_-	hypothetical protein	A0A1S5SDG6	Streptococcus_phage	1.3e-89	92.1
WP_055348619.1\|1490211_1490403_-	DNA-binding protein	A0A1S5SA94	Streptococcus_phage	2.5e-27	95.2
WP_073177132.1\|1490506_1490596_+	type I addiction module toxin, Fst family	NA	NA	NA	NA
WP_073177133.1\|1491011_1491362_+	helix-turn-helix transcriptional regulator	A0A1S5SA75	Streptococcus_phage	2.0e-46	79.3
WP_073177134.1\|1491371_1491755_+	ImmA/IrrE family metallo-endopeptidase	A0A1S5SAG2	Streptococcus_phage	1.9e-66	97.6
WP_073177135.1\|1491770_1492841_+	type I restriction enzyme HsdR N-terminal domain-containing protein	A0A1S5SAB0	Streptococcus_phage	1.9e-180	97.2
WP_000266847.1\|1492963_1494091_+\|integrase	site-specific integrase	A0A1S5SEM0	Streptococcus_phage	4.5e-209	100.0
WP_000011306.1\|1494178_1495090_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.5e-154	99.7
WP_001231086.1\|1495086_1496064_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
WP_000163033.1\|1496060_1496951_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.9e-06	29.8
WP_001140412.1\|1497002_1497383_-	RidA family protein	NA	NA	NA	NA
WP_151892414.1\|1497393_1497981_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_025170719.1\|1497989_1499222_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	3.8e-132	59.2
WP_000442258.1\|1499258_1499429_-	hypothetical protein	NA	NA	NA	NA
WP_000162447.1\|1499428_1499935_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	7.9e-28	43.8
WP_001864315.1\|1500064_1500583_-	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_073177137.1\|1500821_1502336_-\|holin	choline binding-anchored murein hydrolase LytC	NA	NA	NA	NA
1506719:1506751	attR	NA	NA	NA	NA

DBSCAN-SWA_10

1800103 : 1807435

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000167835.1\|1800103_1800805_+	UDP-glucose 4-epimerase	A0A2K9L1R4	Tupanvirus	2.3e-33	35.1
WP_001108391.1\|1800820_1800931_+	hypothetical protein	NA	NA	NA	NA
WP_000777246.1\|1801227_1802187_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.0e-57	40.8
WP_001193668.1\|1802176_1803133_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_000764306.1\|1803129_1803882_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.6e-14	27.9
WP_073177313.1\|1803977_1804943_+	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000821640.1\|1805167_1805410_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.3e-17	59.4
WP_001222228.1\|1805409_1806132_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000105310.1\|1806118_1806688_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
WP_000351907.1\|1806706_1807435_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	5.3e-09	22.3

DBSCAN-SWA_11

2184799 : 2193553

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000510408.1\|2184799_2185639_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	1.5e-15	32.6
WP_000835715.1\|2185623_2186451_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	3.5e-17	33.3
WP_000712132.1\|2186447_2186993_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_001227958.1\|2187003_2187825_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000170189.1\|2187866_2189150_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	8.4e-18	30.0
WP_000424271.1\|2189146_2190397_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.7e-93	42.3
WP_000455903.1\|2190555_2190924_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	7.0e-18	57.3
WP_000266660.1\|2190926_2192024_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_000073428.1\|2192074_2193553_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.2e-94	40.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage