CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP010222	Escherichia coli strain M19 plasmid A, complete sequence	0 crisprs	NA	0	11
NZ_CP010223	Escherichia coli strain M19 plasmid B, complete sequence	0 crisprs	NA	0	0
NZ_CP010221	Escherichia coli strain M19 chromosome, complete genome	6 crisprs	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,csa3,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	13	9
NZ_CP010225	Escherichia coli strain M19 plasmid D, complete sequence	0 crisprs	NA	0	0
NZ_CP010224	Escherichia coli strain M19 plasmid C, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 1501

Morganella_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519984.1\|818_1256_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.1e-25	48.4
WP_073519983.1\|1252_1501_-	DinI-like family protein	Q2A098	Sodalis_phage	4.1e-14	46.7

DBSCAN-SWA_2

9479 : 17968

Pectobacterium_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160537948.1\|9479_9734_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.5e-11	47.5
WP_154813206.1\|9910_10132_-	hypothetical protein	NA	NA	NA	NA
WP_157920373.1\|10196_10346_-	hypothetical protein	NA	NA	NA	NA
WP_073519975.1\|10416_10974_+	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	4.3e-51	74.0
WP_073519974.1\|11025_11268_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_073519973.1\|11337_13335_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	1.1e-21	26.3
WP_097455818.1\|13375_13810_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_073519971.1\|14532_14847_+	theronine dehydrogenase	I3UM57	Rhodobacter_phage	6.4e-12	35.7
WP_073519970.1\|15056_15218_+	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_171769349.1\|15391_15766_+	hypothetical protein	NA	NA	NA	NA
WP_073519969.1\|16658_17003_+	hypothetical protein	A0A248SL90	Klebsiella_phage	9.1e-20	51.5
WP_073519968.1\|17146_17968_+	DUF945 domain-containing protein	A0A2C9CYF8	Yersinia_phage	2.0e-44	39.4

DBSCAN-SWA_3

25757 : 25979

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519957.1\|25757_25979_+	conjugal transfer protein TraR	A0A0F7LDI3	Escherichia_phage	1.7e-06	38.9

DBSCAN-SWA_4

52409 : 53144

Xanthomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519934.1\|52409_53144_+	conjugal transfer pilus acetylase TraX	A0A077JBM8	Xanthomonas_phage	5.9e-08	29.3

DBSCAN-SWA_5

56327 : 57413

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077897982.1\|56327_57413_+	hypothetical protein	H6WZJ9	Escherichia_phage	5.0e-112	58.5

DBSCAN-SWA_6

66789 : 69721

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519925.1\|66789_68943_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	3.4e-27	25.0
WP_073519924.1\|68986_69721_+	type-F conjugative transfer system pilin acetylase TraX	A0A077JBM8	Xanthomonas_phage	3.2e-06	28.1

DBSCAN-SWA_7

79991 : 82181

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519912.1\|79991_82181_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	5.8e-27	26.6

DBSCAN-SWA_8

85889 : 86468

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001400936.1\|85889_86468_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.2e-27	40.2

DBSCAN-SWA_9

91681 : 100398

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519907.1\|91681_95785_+	autotransporter outer membrane beta-barrel domain-containing protein	Q9LA54	Enterobacteria_phage	0.0e+00	45.1
WP_095374788.1\|97124_98318_+	autotransporter outer membrane beta-barrel domain-containing protein	NA	NA	NA	NA
WP_073519905.1\|98542_99181_-	ParB N-terminal domain-containing protein	A0A0F7L444	uncultured_marine_virus	2.8e-54	50.5
WP_073519904.1\|99165_100398_-	phosphoadenosine phosphosulfate reductase	A0A068F1U8	Mycobacterium_phage	6.3e-63	33.4

DBSCAN-SWA_10

114708 : 118638

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519890.1\|114708_118638_-	autotransporter outer membrane beta-barrel domain-containing protein	Q9LA54	Enterobacteria_phage	5.3e-212	37.0

DBSCAN-SWA_11

124603 : 134049

Enterobacteria_phage(50.0%)

integrase,transposase

attL 113369:113382|attR 130534:130547

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
113369:113382	attL	NA	NA	NA	NA
WP_073519885.1\|124603_125344_+\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	1.7e-23	56.6
WP_000361618.1\|125628_126606_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	3.0e-100	59.2
WP_001270417.1\|127534_127822_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	2.2e-19	47.4
WP_001132895.1\|127818_128070_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_032334873.1\|128234_128447_-	hypothetical protein	NA	NA	NA	NA
WP_000817644.1\|128820_130026_+	AAA family ATPase	Q1MVJ3	Enterobacteria_phage	5.6e-205	89.4
WP_000756325.1\|130022_130985_+	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	6.1e-114	68.6
130534:130547	attR	NA	NA	NA	NA
WP_073519881.1\|132903_134049_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	3.8e-219	96.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP010221

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP010221_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010221_1

360133-360893

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR

12 spacers

cas3,cas8e,cse2gr11,cas7

The CRISPR arrays of NZ_CP010221_1

>merge|NZ_CP010221|1|360133-360893|CRISPRCasFinder,CRT,PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCGCCTCCCCGCTCACGCCAACGTTAAACGTTATCGTGTTCCCCGCGCCAGCGGGGATAAACCGACTCAGTCAGCGCGTTAACCCCTTCACACGACGTGTTCCCCGCGCCAGCGGGGATAAACCGGAACGGCGGCTATACGGATTCGACAGGTCAGCGTGTTCCCCGCGCCAGCGGGGATAAACCGTAACCCGGATAACTGGCAGAGTGCGAATAAACGTGTTCCCCGCGCCAGCGGGGATAAACCGCCGGAGATCATCATATTCTGATACGTTCCGGTGTGTTCCCCGCGCCAGCGGGGATAAACCGATTCTTGATCACGCTTTTACCGAAGTAATGGTGTGTTCCCCGCGCCAGCGGGGATAAACCGGCTCCCTGTCAGTTGTAATCGATAACGTTGATGTGTTCCCCGCGCCAGCGGGGATAAACCGATGTAGGGGCAATCGAACGATTCTCTGCCGACGTGTTCCCCGCGCCAGCGGGGATAAACCGCCGAGCCCGATTATCGGCATGAGCGATGCGGAGTGTTCCCCGCGCCAGCGGGGATAAACCGTCGAAGAAGAAAGGGAAATAATGCGAGGAACGGTGTTCCCCGCGCCAGCGGGGATAAACCGTATTACGCGCCAGCAATGCTGACAGCGGCAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGCGAGAGCCAGCAAAACGCCAGGGCACAAAAGAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP010221|1|1|360133-360893|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCTCCCCGCTCACGCCAACGTTAAACGTTATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACTCAGTCAGCGCGTTAACCCCTTCACACGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAACGGCGGCTATACGGATTCGACAGGTCAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAACCCGGATAACTGGCAGAGTGCGAATAAAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGGAGATCATCATATTCTGATACGTTCCGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTCTTGATCACGCTTTTACCGAAGTAATGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATGTAGGGGCAATCGAACGATTCTCTGCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAGCCCGATTATCGGCATGAGCGATGCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGAAGAAGAAAGGGAAATAATGCGAGGAACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCGAGAGCCAGCAAAACGCCAGGGCACAAAA
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP010221|1|1|360133-360893|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCTCCCCGCTCACGCCAACGTTAAACGTTATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACTCAGTCAGCGCGTTAACCCCTTCACACGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAACGGCGGCTATACGGATTCGACAGGTCAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAACCCGGATAACTGGCAGAGTGCGAATAAAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGGAGATCATCATATTCTGATACGTTCCGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTCTTGATCACGCTTTTACCGAAGTAATGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATGTAGGGGCAATCGAACGATTCTCTGCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAGCCCGATTATCGGCATGAGCGATGCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGAAGAAGAAAGGGAAATAATGCGAGGAACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCGAGAGCCAGCAAAACGCCAGGGCACAAAA
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP010221|1|1|360194-360832|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACTCAGTCAGCGCGTTAACCCCTTCACACGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAACGGCGGCTATACGGATTCGACAGGTCAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAACCCGGATAACTGGCAGAGTGCGAATAAAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGGAGATCATCATATTCTGATACGTTCCGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTCTTGATCACGCTTTTACCGAAGTAATGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATGTAGGGGCAATCGAACGATTCTCTGCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAGCCCGATTATCGGCATGAGCGATGCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGAAGAAGAAAGGGAAATAATGCGAGGAACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010221.1\|WP_001199982.1\|359121_359793_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP010221.1\|WP_000211936.1\|362806_364606_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP010221.1\|WP_001071648.1\|352931_353723_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP010221.1\|WP_000254745.1\|352525_352861_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP010221.1\|WP_000034929.1\|357029_357392_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_000793004.1\|357427_358333_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP010221.1\|WP_000039843.1\|366391_367126_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP010221.1\|WP_000108294.1\|362125_362488_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP010221.1\|WP_001290706.1\|364605_366318_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP010221.1\|WP_001317283.1\|361531_362086_-\|carbohydrate-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP010221.1\|WP_000036723.1\|355675_356974_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP010221.1\|WP_000956458.1\|367390_367543_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP010221.1\|WP_000226815.1\|349965_352200_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP010221.1\|WP_001233933.1\|367736_370436_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP010221.1\|WP_000581937.1\|352277_352526_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP010221.1\|WP_000029342.1\|372092_372632_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP010221.1\|WP_001379137.1\|358346_358949_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP010221.1\|WP_000206431.1\|372643_373699_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP010221.1\|WP_000210878.1\|353950_355588_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP010221.1\|WP_001084104.1\|370533_372096_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192

Protein	Function_ID	Function_description	E-value
NZ_CP010221.1\|WP_001199982.1\|359121_359793_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	9.11521e-156
NZ_CP010221.1\|WP_000211936.1\|362806_364606_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP010221.1\|WP_000210878.1\|353950_355588_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP010221.1\|WP_000254745.1\|352525_352861_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NZ_CP010221.1\|WP_001071648.1\|352931_353723_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP010221.1\|WP_000793004.1\|357427_358333_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.06471e-80
NZ_CP010221.1\|WP_000039843.1\|366391_367126_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP010221.1\|WP_000108294.1\|362125_362488_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	1.01593e-59
NZ_CP010221.1\|WP_001290706.1\|364605_366318_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP010221.1\|WP_001317283.1\|361531_362086_-\|carbohydrate-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	5.41884e-35
NZ_CP010221.1\|WP_000036723.1\|355675_356974_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP010221.1\|WP_000956458.1\|367390_367543_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP010221.1\|WP_000226815.1\|349965_352200_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP010221.1\|WP_001233933.1\|367736_370436_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.31706e-179
NZ_CP010221.1\|WP_000581937.1\|352277_352526_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP010221.1\|WP_000029342.1\|372092_372632_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	7.30002e-26
NZ_CP010221.1\|WP_001379137.1\|358346_358949_-\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	1.00218e-77
NZ_CP010221.1\|WP_000206431.1\|372643_373699_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	6.10696e-155
NZ_CP010221.1\|WP_001084104.1\|370533_372096_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0

>NZ_CP010221.1|WP_001199982.1|359121_359793_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGSASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP010221.1|WP_001379137.1|358346_358949_-|LemA-family-protein
MLRTFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSNHEKDVLEAVTLARSQANRASSDLQQTPGNEQKLQAWQQAQAQVTRTLGQLTIISERYPELKAQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNASAH
>NZ_CP010221.1|WP_000793004.1|357427_358333_-|YgcG-family-protein
MKNLILLLVLICSSAFAVQVPVPEFAKYINDLTGTLTREEVSTLTSQIKTLTQKSHAQLIVLVVETTGDETIEQYATRVFERWQPGHKNLDDGILLVVAWQDHTVHIEIGYGLEGILTDAQSGQIIRNSIIPAFKKGDLAVGLQQGIGDIETRLSENDLVNNTSPDHPLPFSGWWALLVWAIVLTFISARGYVKTLGVICFAAIILAFVLPIAGYSGSWGVLATLLCFATPFLVVAIAFTPFGRKVRDSMRSANRPSRYERSNSASRHSSSSSSSSSSSFNNDNFSGGGGSSGGGGASGRW
>NZ_CP010221.1|WP_000034929.1|357029_357392_-|hypothetical-protein
MSKILANHPRLSKFVFGLFGAAGMIWLNKAFQGDELFQLITSLLALDTFVYFCIYSLINPIPEANDFLWDYKVHQRKYSSNISHNDFVSNVRNSRKIVRILILVGITFINVIALLTKLKM
>NZ_CP010221.1|WP_000036723.1|355675_356974_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP010221.1|WP_000210878.1|353950_355588_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP010221.1|WP_001071648.1|352931_353723_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP010221.1|WP_000254745.1|352525_352861_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP010221.1|WP_000581937.1|352277_352526_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP010221.1|WP_000226815.1|349965_352200_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP010221.1|WP_001317283.1|361531_362086_-|carbohydrate-kinase
MLGCCVLDIWGMTWKTTATLLLLVPVLQAPLARYAWIYRSILESVALMLKNNYDNMRNEMNHFAKHVIITGGGSNSDLFMQIFADMFNLPARRNAINGCASLGAAINKAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHNDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP010221.1|WP_000108294.1|362125_362488_-|6-carboxytetrahydropterin-synthase-QueD
MSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>NZ_CP010221.1|WP_000211936.1|362806_364606_+|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLTGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGELRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>NZ_CP010221.1|WP_001290706.1|364605_366318_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>NZ_CP010221.1|WP_000039843.1|366391_367126_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP010221.1|WP_000956458.1|367390_367543_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP010221.1|WP_001233933.1|367736_370436_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>NZ_CP010221.1|WP_001084104.1|370533_372096_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPDSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP010221.1|WP_000029342.1|372092_372632_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP010221.1|WP_000206431.1|372643_373699_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWSAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA

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Crispr_ID: NZ_CP010221_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010221_2

376395-376911

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

8 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP010221_2

>merge|NZ_CP010221|2|376395-376911|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGCGCGCGACTACTGCCCGACCCGCCGACAACAGTGTTCCCCGCGCCAGCGGGGATAAACCCGACTTTGCCCGGATAAGCAATGGCGATACGTCGTGTTCCCCGCGCCAGCGGGGATAAACCGCTCCGACTTACCGTAGTGATGGCGCGCTGCCAGTGTTCCCCGCGCCAGCGGGGATAAACCGAATTTCTGGAAAAAAACAAATTCAAAAAATTGGTGTTCCCCGCGCCAGCGGGGATAAACCGTGACTGCGGTTCAAAATCTCCGGCACACGTCCGTGTTCCCCGCGCCAGCGGGGATAAACCGGCCGCGCCGCACTGGCGCTGGCACGGTATGCAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCCTCACGGGCTATTTGGTTAATCGAAAATTAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCAGCCCTTGTTAACGTCTTCGCCGTTCGGGTGTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP010221|2|2|376395-376911|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCGCGACTACTGCCCGACCCGCCGACAACA
GTGTTCCCCGCGCCAGCGGGGATAAACCC	GACTTTGCCCGGATAAGCAATGGCGATACGTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCCGACTTACCGTAGTGATGGCGCGCTGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTCTGGAAAAAAACAAATTCAAAAAATTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGACTGCGGTTCAAAATCTCCGGCACACGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCCGCGCCGCACTGGCGCTGGCACGGTATGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCTCACGGGCTATTTGGTTAATCGAAAATTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGCCCTTGTTAACGTCTTCGCCGTTCGGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP010221|2|2|376395-376911|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCGCGACTACTGCCCGACCCGCCGACAACA
GTGTTCCCCGCGCCAGCGGGGATAAACCC	GACTTTGCCCGGATAAGCAATGGCGATACGTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCCGACTTACCGTAGTGATGGCGCGCTGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTCTGGAAAAAAACAAATTCAAAAAATTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGACTGCGGTTCAAAATCTCCGGCACACGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCCGCGCCGCACTGGCGCTGGCACGGTATGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCTCACGGGCTATTTGGTTAATCGAAAATTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGCCCTTGTTAACGTCTTCGCCGTTCGGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP010221|2|2|376395-376911|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCGCGACTACTGCCCGACCCGCCGACAACA
GTGTTCCCCGCGCCAGCGGGGATAAACCC	GACTTTGCCCGGATAAGCAATGGCGATACGTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCCGACTTACCGTAGTGATGGCGCGCTGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTCTGGAAAAAAACAAATTCAAAAAATTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGACTGCGGTTCAAAATCTCCGGCACACGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCCGCGCCGCACTGGCGCTGGCACGGTATGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCTCACGGGCTATTTGGTTAATCGAAAATTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGCCCTTGTTAACGTCTTCGCCGTTCGGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010221.1\|WP_001173673.1\|380618_381224_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP010221.1\|WP_000246138.1\|382120_382831_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP010221.1\|WP_000085068.1\|373709_374456_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP010221.1\|WP_000206431.1\|372643_373699_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP010221.1\|WP_001295182.1\|384336_385098_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP010221.1\|WP_000039843.1\|366391_367126_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP010221.1\|WP_001219242.1\|382830_383310_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP010221.1\|WP_000956458.1\|367390_367543_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP010221.1\|WP_000568943.1\|383306_384356_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP010221.1\|WP_000372108.1\|378281_379190_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP010221.1\|WP_000029342.1\|372092_372632_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP010221.1\|WP_000281434.1\|374437_375088_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP010221.1\|WP_000490403.1\|376992_378030_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP010221.1\|WP_001233933.1\|367736_370436_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP010221.1\|WP_000144875.1\|375084_376005_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP010221.1\|WP_000517476.1\|381790_382102_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP010221.1\|WP_001246104.1\|381273_381597_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP010221.1\|WP_000063176.1\|376004_376298_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP010221.1\|WP_001090345.1\|379191_380619_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP010221.1\|WP_001084104.1\|370533_372096_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192

Protein	Function_ID	Function_description	E-value
NZ_CP010221.1\|WP_001173673.1\|380618_381224_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP010221.1\|WP_000246138.1\|382120_382831_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP010221.1\|WP_000085068.1\|373709_374456_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.95914e-49
NZ_CP010221.1\|WP_000206431.1\|372643_373699_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	6.10696e-155
NZ_CP010221.1\|WP_001295182.1\|384336_385098_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP010221.1\|WP_000039843.1\|366391_367126_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP010221.1\|WP_001219242.1\|382830_383310_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP010221.1\|WP_000956458.1\|367390_367543_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP010221.1\|WP_000568943.1\|383306_384356_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP010221.1\|WP_000372108.1\|378281_379190_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP010221.1\|WP_000029342.1\|372092_372632_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	7.30002e-26
NZ_CP010221.1\|WP_000281434.1\|374437_375088_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.16907e-91
NZ_CP010221.1\|WP_000490403.1\|376992_378030_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP010221.1\|WP_001233933.1\|367736_370436_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.31706e-179
NZ_CP010221.1\|WP_000144875.1\|375084_376005_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.70125e-157
NZ_CP010221.1\|WP_000517476.1\|381790_382102_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP010221.1\|WP_001246104.1\|381273_381597_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP010221.1\|WP_000063176.1\|376004_376298_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP010221.1\|WP_001090345.1\|379191_380619_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP010221.1\|WP_001084104.1\|370533_372096_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0

>NZ_CP010221.1|WP_000063176.1|376004_376298_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP010221.1|WP_000144875.1|375084_376005_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLINKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRG
>NZ_CP010221.1|WP_000281434.1|374437_375088_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQARPAESETFTIECRPFVSELRTGQSLCFNLRANPTICKAGKRHDLLMEAKRQVKGQAEGRDIWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENTRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP010221.1|WP_000085068.1|373709_374456_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP010221.1|WP_000206431.1|372643_373699_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWSAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP010221.1|WP_000029342.1|372092_372632_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP010221.1|WP_001084104.1|370533_372096_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPDSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP010221.1|WP_001233933.1|367736_370436_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>NZ_CP010221.1|WP_000956458.1|367390_367543_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP010221.1|WP_000039843.1|366391_367126_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP010221.1|WP_000490403.1|376992_378030_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP010221.1|WP_000372108.1|378281_379190_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP010221.1|WP_001090345.1|379191_380619_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARIDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPKNEAAVASSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP010221.1|WP_001173673.1|380618_381224_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP010221.1|WP_001246104.1|381273_381597_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP010221.1|WP_000517476.1|381790_382102_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP010221.1|WP_000246138.1|382120_382831_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP010221.1|WP_001219242.1|382830_383310_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP010221.1|WP_000568943.1|383306_384356_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP010221.1|WP_001295182.1|384336_385098_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP010221_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010221_3

1590898-1591021

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010221_3

>merge|NZ_CP010221|3|1590898-1591021|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP010221|3|3|1590898-1591021|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010221.1\|WP_001295403.1\|1580351_1581764_-\|pyruvate-kinase-PykF	unknown	unknown	gnl\|CDD\|181699
NZ_CP010221.1\|WP_000587560.1\|1587903_1588716_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP010221.1\|WP_001299088.1\|1585747_1586386_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP010221.1\|WP_000528342.1\|1582320_1582530_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP010221.1\|WP_000716922.1\|1588727_1590332_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP010221.1\|WP_073519645.1\|1591335_1592592_+\|AIDA-repeat-containing-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP010221.1\|WP_001174946.1\|1592632_1594006_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP010221.1\|WP_000269501.1\|1597664_1598597_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP010221.1\|WP_000493947.1\|1594220_1594862_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP010221.1\|WP_000212657.1\|1590457_1590763_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP010221.1\|WP_001070230.1\|1582985_1583612_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP010221.1\|WP_001182362.1\|1596340_1597552_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP010221.1\|WP_000102278.1\|1599917_1600007_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP010221.1\|WP_000098911.1\|1594901_1596050_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP010221.1\|WP_000701040.1\|1600172_1601342_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP010221.1\|WP_001069997.1\|1587114_1587900_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP010221.1\|WP_001349911.1\|1586449_1587118_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP010221.1\|WP_001273518.1\|1583632_1585735_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP010221.1\|WP_000007283.1\|1601487_1602069_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP010221.1\|WP_000190982.1\|1598593_1599619_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739

Protein	Function_ID	Function_description	E-value
NZ_CP010221.1\|WP_001295403.1\|1580351_1581764_-\|pyruvate-kinase-PykF	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP010221.1\|WP_000587560.1\|1587903_1588716_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.20825e-175
NZ_CP010221.1\|WP_001299088.1\|1585747_1586386_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	1.44183e-120
NZ_CP010221.1\|WP_000528342.1\|1582320_1582530_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP010221.1\|WP_000716922.1\|1588727_1590332_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP010221.1\|WP_073519645.1\|1591335_1592592_+\|AIDA-repeat-containing-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP010221.1\|WP_001174946.1\|1592632_1594006_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP010221.1\|WP_000269501.1\|1597664_1598597_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP010221.1\|WP_000493947.1\|1594220_1594862_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP010221.1\|WP_000212657.1\|1590457_1590763_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
NZ_CP010221.1\|WP_001070230.1\|1582985_1583612_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP010221.1\|WP_001182362.1\|1596340_1597552_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP010221.1\|WP_000098911.1\|1594901_1596050_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP010221.1\|WP_000701040.1\|1600172_1601342_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
NZ_CP010221.1\|WP_001069997.1\|1587114_1587900_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.33298e-163
NZ_CP010221.1\|WP_001349911.1\|1586449_1587118_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	7.32003e-76
NZ_CP010221.1\|WP_001273518.1\|1583632_1585735_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP010221.1\|WP_000007283.1\|1601487_1602069_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP010221.1\|WP_000190982.1\|1598593_1599619_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0

>NZ_CP010221.1|WP_000212657.1|1590457_1590763_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP010221.1|WP_000716922.1|1588727_1590332_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP010221.1|WP_000587560.1|1587903_1588716_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC
>NZ_CP010221.1|WP_001069997.1|1587114_1587900_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP010221.1|WP_001349911.1|1586449_1587118_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP010221.1|WP_001299088.1|1585747_1586386_+|YdhW-family-putative-oxidoreductase-system-protein
MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSVAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP010221.1|WP_001273518.1|1583632_1585735_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIHWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>NZ_CP010221.1|WP_001070230.1|1582985_1583612_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP010221.1|WP_000528342.1|1582320_1582530_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP010221.1|WP_001295403.1|1580351_1581764_-|pyruvate-kinase-PykF
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP010221.1|WP_073519645.1|1591335_1592592_+|AIDA-repeat-containing-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGWAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFSVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP010221.1|WP_001174946.1|1592632_1594006_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVKPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
>NZ_CP010221.1|WP_000493947.1|1594220_1594862_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP010221.1|WP_000098911.1|1594901_1596050_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP010221.1|WP_001182362.1|1596340_1597552_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVDCQNHGNAEVAHSESH
>NZ_CP010221.1|WP_000269501.1|1597664_1598597_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP010221.1|WP_000190982.1|1598593_1599619_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP010221.1|WP_000102278.1|1599917_1600007_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP010221.1|WP_000701040.1|1600172_1601342_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP010221.1|WP_000007283.1|1601487_1602069_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Crispr_ID: NZ_CP010221_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010221_4

2218587-2218678

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010221_4

>merge|NZ_CP010221|4|2218587-2218678|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP010221|4|4|2218587-2218678|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010221.1\|WP_016239908.1\|2222997_2223213_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_001028105.1\|2216629_2217124_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NZ_CP010221.1\|WP_042024037.1\|2225280_2225484_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_000979516.1\|2207837_2208047_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_073519687.1\|2227880_2228654_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_001349943.1\|2208101_2212064_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP010221.1\|WP_001126777.1\|2214824_2215211_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP010221.1\|WP_001345413.1\|2215218_2216019_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP010221.1\|WP_073519684.1\|2222716_2222998_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_073519688.1\|2228673_2230317_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|377856
NZ_CP010221.1\|WP_073519682.1\|2219713_2220262_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP010221.1\|WP_001331086.1\|2212103_2212742_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP010221.1\|WP_001297176.1\|2213029_2214121_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP010221.1\|WP_000805963.1\|2223209_2223497_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|379158
NZ_CP010221.1\|WP_073519685.1\|2223655_2223979_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_001504154.1\|2217144_2218473_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP010221.1\|WP_001307708.1\|2214120_2214813_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP010221.1\|WP_073521383.1\|2222157_2222715_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_073519686.1\|2225592_2227716_+\|tape-measure-protein	unknown	unknown	gnl\|CDD\|226450
NZ_CP010221.1\|WP_073519681.1\|2216028_2216619_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040

Protein	Function_ID	Function_description	E-value
NZ_CP010221.1\|WP_001028105.1\|2216629_2217124_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	2.76325e-105
NZ_CP010221.1\|WP_001349943.1\|2208101_2212064_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP010221.1\|WP_001126777.1\|2214824_2215211_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	6.69692e-84
NZ_CP010221.1\|WP_001345413.1\|2215218_2216019_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	1.24393e-141
NZ_CP010221.1\|WP_073519688.1\|2228673_2230317_-\|recombinase-family-protein	gnl\|CDD\|377856	pfam07508, Recombinase, Recombinase. This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages.	1.31191e-18
NZ_CP010221.1\|WP_073519682.1\|2219713_2220262_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	3.16836e-48
NZ_CP010221.1\|WP_001331086.1\|2212103_2212742_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	8.77004e-153
NZ_CP010221.1\|WP_001297176.1\|2213029_2214121_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP010221.1\|WP_000805963.1\|2223209_2223497_+\|HNH-endonuclease	gnl\|CDD\|379158	pfam13392, HNH_3, HNH endonuclease. This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.	1.74878e-05
NZ_CP010221.1\|WP_073519686.1\|2225592_2227716_+\|tape-measure-protein	gnl\|CDD\|226450	COG3941, COG3941, Mu-like prophage protein [General function prediction only].	5.82594e-09
NZ_CP010221.1\|WP_001504154.1\|2217144_2218473_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP010221.1\|WP_001307708.1\|2214120_2214813_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	5.84226e-169
NZ_CP010221.1\|WP_073519681.1\|2216028_2216619_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	2.26533e-130

>NZ_CP010221.1|WP_001504154.1|2217144_2218473_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPYERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNLLGLGKAVDFTLVSHAAWFGLPHFSTPAFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDSYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>NZ_CP010221.1|WP_001028105.1|2216629_2217124_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSARQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
>NZ_CP010221.1|WP_073519681.1|2216028_2216619_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYPLMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
>NZ_CP010221.1|WP_001345413.1|2215218_2216019_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP010221.1|WP_001126777.1|2214824_2215211_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLEIIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP010221.1|WP_001307708.1|2214120_2214813_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>NZ_CP010221.1|WP_001297176.1|2213029_2214121_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP010221.1|WP_001331086.1|2212103_2212742_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTKGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
>NZ_CP010221.1|WP_001349943.1|2208101_2212064_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEAILSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP010221.1|WP_000979516.1|2207837_2208047_-|hypothetical-protein
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NZ_CP010221.1|WP_073519682.1|2219713_2220262_+|recombinase-family-protein
MAVIGYCRVSTQDQTVDNQKLQIEKVHKVDKWFIDEAVSGTTKATSRDGFRDMMNYVRCDDTLVVVAIDRLGRNTVDVLSNVESLQSKGVRVVSLREGFDLLTPIGRAMLTMMAGLADLEKDLISERRKAGIERAKAEGVHMGRPVKASSETVKTLISQGKTRLQIQEELGISRATYYRLAK
>NZ_CP010221.1|WP_073521383.1|2222157_2222715_+|hypothetical-protein
MRDAEFRAMLQASRQRNRYNSYSYTDTPTSHEVPKFTRAERKGIDEVIRAITPRSRYMSTRKSTQNTIKNYLANFDSYEQLPSKIEDVIIGFCRSEGHPKYNKKLFYLLKNLDEINSATVTNYLQRQATRLSYELPSDKYCALLAVMCAKLIGVVEHHVAVGNIEPMENEQPDFEFDPYLVTEEF
>NZ_CP010221.1|WP_073519684.1|2222716_2222998_+|hypothetical-protein
MKNKHTLTRISEEAFNELTRIKRATNLPHQTVMQLAIAKEVTESDLLKYPVSKGRKHIRISQDALDTLKALNSFKIDIARLLSLKIHKLSMEV
>NZ_CP010221.1|WP_016239908.1|2222997_2223213_+|hypothetical-protein
MLCVTFEYHTDKMIRYISDLLIKGNGFGDIHNSKDIFIKAIGPNEVLKAAVRPEWFERHKIELGYWGEEVL
>NZ_CP010221.1|WP_000805963.1|2223209_2223497_+|HNH-endonuclease
MKPWHEDVRRYFTEHLIYDESSDSLCWSDGESVTINTDDYGNKTFNIGRYTFYVKYVVWFLYHGYQSNKQIIHRNGNRADTRPKNLMQVRDFKRN
>NZ_CP010221.1|WP_073519685.1|2223655_2223979_+|hypothetical-protein
MNNFPLQIFVDSDTAMMVQSFTDAGISIDFDRLLKLMADNSETIEDFIQEIETGDPRFMFPVTDSNMKRLVIEQTNKHSVSPEKYLKAAIAILYADNILVTDSKVVH
>NZ_CP010221.1|WP_042024037.1|2225280_2225484_+|hypothetical-protein
MIDLTERYELIKAISERLKEQPNKPKRIKSSTSKQNNRIRRIAKWCLDKLPSDCQIVGEDGNYYLIK
>NZ_CP010221.1|WP_073519686.1|2225592_2227716_+|tape-measure-protein
MAQFKVDDFLIELSFNSQKVLKGLEKAEKQTMQVASRIEKRLNKAFKVNPTPLNDSLKLMEKNVDKTVSKIEQRLKNTKAFKIKTEIEDTLKPLRQPRQPRISGNRAITAAYSANMSKLKGLNPIVEKYIKSQFYALSSKSKTLGNEAFNRELAKLNQNLRETLSKFNKTTSKNNHSENASNGLDVLASSAIKAGTAIYTFQSALAAYQRVMEIGLQRASAERSIDFVFDKDANQVKAFTKSLAQTTGLDIAELQSQFAGFGASAKESMGIQGSEELFRNMIGYSRLMGRSEEEIKRALTALSQMAGKGQIMAEELKGQLAEAVPGMVQVFAKATGKTEQELFDAMKKGALKSADTLQKVTQELNKQITAKGGWKTISESTQAQLGNLKNSWNTTLDSIFRGSENGLQDFTRSLTTLLNSLGGSGKSLGESLGSLMTSMSHGVDSLTDISYRVRAFFDEVTLAYRSLNDTQKKIVDGLSDGLIDGLKMLAVAVTAQKAANVAGGLLNLANAVTSFGDAVNKAKAGKAGSSGGALSKVGRVVLYAELVNFALDNLNPEAAKNPNLHQSGIGTETNFNPEYKGDSSKPNQINDGWAKIGSSIADWFNGAANKIANFQEPMSNLVNNTQSTPPAITGDMVNSNAQLAMTISELSRKVDALTAETKKPLLVNITGEATVRPDEPAFFTFNQSANDQFTQDMLLSSSYPEEE
>NZ_CP010221.1|WP_073519687.1|2227880_2228654_+|hypothetical-protein
MIFSNQIRYSGKDGIYFHLRDNVDAFLTLSATENMEFDSPMQVTTQNMQSGQTVTDNVQRAPRTITISGVVVVGYEGSLLLTRQGQLVENFIDTLESWRDQKQIISVICKDGIKIDDSIITSFKASKDVGISNGLRIQLTFQEINFKAVVGQTDISAATGKAATTNDGGATSKKNAGNVTTERNNAPMLMCQELYSYSASELSDEALRVRSNCSKNVTVKDGVSTFTASANSGAAKVLKAGNALRKFSVNPNKKGTY
>NZ_CP010221.1|WP_073519688.1|2228673_2230317_-|recombinase-family-protein
MKLLVPYIRWSTKEQDSGDSLRRQTNLIDAFYSKHKEEYYLLPAHRYVDKGKSGFHQQHKAQGSDFRRMFENVMSGAIPEGSLIVVENFDRFSRADIDTAIDDVRQILRKGVSILTLGDGELYDKSALTDPVKLIKHIIIAERAHQESLVKQKRIAQVWNHKTQLARELKKPMGKQAPGWLELSEDGSHYIVDEDKASLVNIIYDKRLSGMSMFAICKWLNEQGYPTINQRKVRISKTKKPDGNWSALSVKHILTSRSVLGYLPAKISSEDRKTVLREEIEGFYPQIVTDSKFYAVQQLLEETGKGKTSSGEHWLYVNILKGLIRCKCGLVMTPTGIRKPVYQGTYRCNGNKESRCNYGTVSRKLLDTQLCSRLFSKLSQLHDEATDTARLDELQRRLNTVDGELEKLTETLIQLPNITQIQEALRVKQEEKDELIVQLSREKARVKSVSSLDLSGLDMESVEGRTEAQIIIKRLVKEIVVSGNEKLVDIYLHNGNMIRGFPLDGKDDHTLTLEEATDEMQSLDDMLIFGEPVTRIYPAGDMEEVDA

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Crispr_ID: NZ_CP010221_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010221_5

2534407-2534551

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010221_5

>merge|NZ_CP010221|5|2534407-2534551|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>NZ_CP010221|5|5|2534407-2534551|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010221.1\|WP_073519737.1\|2533057_2534341_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP010221.1\|WP_000815441.1\|2540757_2541753_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NZ_CP010221.1\|WP_000042533.1\|2524791_2526813_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_CP010221.1\|WP_000723652.1\|2538527_2539580_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
NZ_CP010221.1\|WP_000113005.1\|2544476_2545250_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NZ_CP010221.1\|WP_000767389.1\|2532429_2532906_+\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
NZ_CP010221.1\|WP_000604032.1\|2543787_2544477_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_CP010221.1\|WP_000044868.1\|2527391_2528069_-\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
NZ_CP010221.1\|WP_000118833.1\|2528803_2529958_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_CP010221.1\|WP_001036486.1\|2537018_2538452_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP010221.1\|WP_000246805.1\|2528061_2528817_-\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340
NZ_CP010221.1\|WP_000951213.1\|2529954_2530995_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|185063
NZ_CP010221.1\|WP_001389241.1\|2531081_2532371_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189
NZ_CP010221.1\|WP_001295301.1\|2522305_2523295_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP010221.1\|WP_000593936.1\|2534574_2536836_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NZ_CP010221.1\|WP_000213425.1\|2541907_2542726_+\|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase	unknown	unknown	gnl\|CDD\|182523
NZ_CP010221.1\|WP_001356069.1\|2539763_2540717_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP010221.1\|WP_000891683.1\|2542726_2543785_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP010221.1\|WP_001295302.1\|2523691_2524600_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689
NZ_CP010221.1\|WP_000891515.1\|2545416_2545566_-\|multidrug-efflux-pump-accessory-protein-AcrZ	unknown	unknown	gnl\|CDD\|371231

Protein	Function_ID	Function_description	E-value
NZ_CP010221.1\|WP_073519737.1\|2533057_2534341_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP010221.1\|WP_000815441.1\|2540757_2541753_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NZ_CP010221.1\|WP_000042533.1\|2524791_2526813_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP010221.1\|WP_000723652.1\|2538527_2539580_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NZ_CP010221.1\|WP_000113005.1\|2544476_2545250_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
NZ_CP010221.1\|WP_000767389.1\|2532429_2532906_+\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	1.08182e-118
NZ_CP010221.1\|WP_000604032.1\|2543787_2544477_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	9.04539e-146
NZ_CP010221.1\|WP_000044868.1\|2527391_2528069_-\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	7.09172e-110
NZ_CP010221.1\|WP_000118833.1\|2528803_2529958_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
NZ_CP010221.1\|WP_001036486.1\|2537018_2538452_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NZ_CP010221.1\|WP_000246805.1\|2528061_2528817_-\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	1.57982e-172
NZ_CP010221.1\|WP_000951213.1\|2529954_2530995_-\|biotin-synthase-BioB	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
NZ_CP010221.1\|WP_001389241.1\|2531081_2532371_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
NZ_CP010221.1\|WP_001295301.1\|2522305_2523295_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	0
NZ_CP010221.1\|WP_000593936.1\|2534574_2536836_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NZ_CP010221.1\|WP_000213425.1\|2541907_2542726_+\|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
NZ_CP010221.1\|WP_001356069.1\|2539763_2540717_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.3313e-82
NZ_CP010221.1\|WP_000891683.1\|2542726_2543785_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP010221.1\|WP_001295302.1\|2523691_2524600_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.22556e-139
NZ_CP010221.1\|WP_000891515.1\|2545416_2545566_-\|multidrug-efflux-pump-accessory-protein-AcrZ	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17

>NZ_CP010221.1|WP_073519737.1|2533057_2534341_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDLVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQCNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NZ_CP010221.1|WP_000767389.1|2532429_2532906_+|kinase-inhibitor
MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTGYDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS
>NZ_CP010221.1|WP_001389241.1|2531081_2532371_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHTPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEYAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPARNAEMVADVRVLGAIGVVETTRPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ
>NZ_CP010221.1|WP_000951213.1|2529954_2530995_-|biotin-synthase-BioB
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>NZ_CP010221.1|WP_000118833.1|2528803_2529958_-|8-amino-7-oxononanoate-synthase
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFAHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRRDEGDARREKLVSLIARFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>NZ_CP010221.1|WP_000246805.1|2528061_2528817_-|malonyl-ACP-O-methyltransferase-BioC
MATVNKQAIAAAFGRAAALYEQHADLQRQSADVLLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERPHANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE
>NZ_CP010221.1|WP_000044868.1|2527391_2528069_-|ATP-dependent-dethiobiotin-synthetase-BioD
MSKRYFVTGTDTEVGKTVASCALLQAAKAVGYRTAGYKPVASGSEKTPEGLRNSDALALQHNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL
>NZ_CP010221.1|WP_000042533.1|2524791_2526813_-|excinuclease-ABC-subunit-B
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>NZ_CP010221.1|WP_001295302.1|2523691_2524600_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTPIQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQLLHNALEKALQALG
>NZ_CP010221.1|WP_001295301.1|2522305_2523295_-|GTP-3',8-cyclase-MoaA
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
>NZ_CP010221.1|WP_000593936.1|2534574_2536836_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NZ_CP010221.1|WP_001036486.1|2537018_2538452_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGSTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NZ_CP010221.1|WP_000723652.1|2538527_2539580_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NZ_CP010221.1|WP_001356069.1|2539763_2540717_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRHKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>NZ_CP010221.1|WP_000815441.1|2540757_2541753_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQRQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NZ_CP010221.1|WP_000213425.1|2541907_2542726_+|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NZ_CP010221.1|WP_000891683.1|2542726_2543785_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMAKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>NZ_CP010221.1|WP_000604032.1|2543787_2544477_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITIPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NZ_CP010221.1|WP_000113005.1|2544476_2545250_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNTLADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>NZ_CP010221.1|WP_000891515.1|2545416_2545566_-|multidrug-efflux-pump-accessory-protein-AcrZ
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: NZ_CP010221_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010221_6

4928274-4928391

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010221_6

>merge|NZ_CP010221|6|4928274-4928391|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>NZ_CP010221|6|6|4928274-4928391|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010221.1\|WP_000719990.1\|4923483_4923873_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP010221.1\|WP_001198780.1\|4930404_4930761_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP010221.1\|WP_000531201.1\|4931660_4932647_-\|glutathionyl-hydroquinone-reductase-YqjG	unknown	unknown	gnl\|CDD\|223512
NZ_CP010221.1\|WP_000145836.1\|4915995_4916340_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP010221.1\|WP_000096086.1\|4933294_4933594_-\|YqjK-like-family-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP010221.1\|WP_000104211.1\|4916528_4917467_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP010221.1\|WP_001295544.1\|4928464_4928629_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010221.1\|WP_001297162.1\|4919933_4921142_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP010221.1\|WP_000107720.1\|4918576_4919908_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP010221.1\|WP_000622115.1\|4923944_4925309_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP010221.1\|WP_000548347.1\|4917565_4918555_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP010221.1\|WP_000401598.1\|4925583_4926915_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP010221.1\|WP_000861734.1\|4921175_4923470_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NZ_CP010221.1\|WP_000785722.1\|4933583_4933988_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP010221.1\|WP_000633577.1\|4928651_4929353_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP010221.1\|WP_000031415.1\|4933990_4934296_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP010221.1\|WP_001041010.1\|4929457_4930354_+\|DNA-binding-transcriptional-regulator-YhaJ	unknown	unknown	gnl\|CDD\|176122
NZ_CP010221.1\|WP_000460519.1\|4926942_4928253_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP010221.1\|WP_000732233.1\|4932716_4933109_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP010221.1\|WP_000384145.1\|4931002_4931368_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694

Protein	Function_ID	Function_description	E-value
NZ_CP010221.1\|WP_000719990.1\|4923483_4923873_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP010221.1\|WP_001198780.1\|4930404_4930761_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35
NZ_CP010221.1\|WP_000531201.1\|4931660_4932647_-\|glutathionyl-hydroquinone-reductase-YqjG	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP010221.1\|WP_000145836.1\|4915995_4916340_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	1.4676e-66
NZ_CP010221.1\|WP_000096086.1\|4933294_4933594_-\|YqjK-like-family-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP010221.1\|WP_000104211.1\|4916528_4917467_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP010221.1\|WP_000633577.1\|4928651_4929353_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.02982e-67
NZ_CP010221.1\|WP_001297162.1\|4919933_4921142_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP010221.1\|WP_000107720.1\|4918576_4919908_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP010221.1\|WP_000622115.1\|4923944_4925309_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP010221.1\|WP_000548347.1\|4917565_4918555_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP010221.1\|WP_000401598.1\|4925583_4926915_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53913e-167
NZ_CP010221.1\|WP_000861734.1\|4921175_4923470_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP010221.1\|WP_000785722.1\|4933583_4933988_-\|phage-holin-family-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP010221.1\|WP_000031415.1\|4933990_4934296_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP010221.1\|WP_001041010.1\|4929457_4930354_+\|DNA-binding-transcriptional-regulator-YhaJ	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
NZ_CP010221.1\|WP_000460519.1\|4926942_4928253_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0
NZ_CP010221.1\|WP_000732233.1\|4932716_4933109_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	3.31068e-25
NZ_CP010221.1\|WP_000384145.1\|4931002_4931368_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42

>NZ_CP010221.1|WP_000460519.1|4926942_4928253_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP010221.1|WP_000401598.1|4925583_4926915_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP010221.1|WP_000622115.1|4923944_4925309_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP010221.1|WP_000719990.1|4923483_4923873_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP010221.1|WP_000861734.1|4921175_4923470_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP010221.1|WP_001297162.1|4919933_4921142_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP010221.1|WP_000107720.1|4918576_4919908_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP010221.1|WP_000548347.1|4917565_4918555_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP010221.1|WP_000104211.1|4916528_4917467_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP010221.1|WP_000145836.1|4915995_4916340_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP010221.1|WP_001295544.1|4928464_4928629_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP010221.1|WP_000633577.1|4928651_4929353_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>NZ_CP010221.1|WP_001041010.1|4929457_4930354_+|DNA-binding-transcriptional-regulator-YhaJ
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>NZ_CP010221.1|WP_001198780.1|4930404_4930761_-|DUF805-domain-containing-protein
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>NZ_CP010221.1|WP_000384145.1|4931002_4931368_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP010221.1|WP_000531201.1|4931660_4932647_-|glutathionyl-hydroquinone-reductase-YqjG
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP010221.1|WP_000732233.1|4932716_4933109_-|DoxX-family-protein
MKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP010221.1|WP_000096086.1|4933294_4933594_-|YqjK-like-family-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP010221.1|WP_000785722.1|4933583_4933988_-|phage-holin-family-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP010221.1|WP_000031415.1|4933990_4934296_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP010221_4	4.1\|2218613\|40\|NZ_CP010221\|CRISPRCasFinder	2218613-2218652	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
NZ_CP010221_2	2.8\|376851\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376851-376882	32	MK972713	Salmonella phage SW5, complete genome	13980-14011	2	0.938
NZ_CP010221_2	2.8\|376851\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376851-376882	32	MK972714	Salmonella phage SW3, complete genome	14202-14233	2	0.938
NZ_CP010221_2	2.8\|376851\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376851-376882	32	NC_049460	Salmonella phage SI7, complete genome	4422-4453	2	0.938
NZ_CP010221_3	3.1\|1590941\|38\|NZ_CP010221\|CRISPRCasFinder	1590941-1590978	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP010221_2	2.1\|376424\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376424-376455	32	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	27818-27849	5	0.844
NZ_CP010221_1	1.6\|360467\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360467-360498	32	MG592456	Vibrio phage 1.081.O._10N.286.52.C2, partial genome	219798-219829	6	0.812
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NC_017804	Borreliella garinii BgVir plasmid lp54, complete sequence	27596-27627	7	0.781
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	CP022460	Shigella sonnei strain 2015C-3807 plasmid unnamed1, complete sequence	32099-32130	7	0.781
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	NZ_CP015232	Epibacterium mobile F1926 plasmid unnamed2, complete sequence	112025-112056	7	0.781
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	NZ_LR027555	Epibacterium mobile isolate EPIB1 plasmid 3, complete sequence	90457-90488	7	0.781
NZ_CP010221_1	1.9\|360650\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360650-360681	32	NZ_CP038236	Leisingera sp. NJS201 plasmid unnamed2, complete sequence	2813-2844	8	0.75
NZ_CP010221_1	1.9\|360650\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360650-360681	32	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	353558-353589	8	0.75
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NZ_CP014203	Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence	11893-11924	8	0.75
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NC_015254	Brochothrix phage BL3, complete genome	25082-25113	8	0.75
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	8127-8158	8	0.75
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NZ_CP010112	Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-6, complete sequence	87042-87073	8	0.75
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	169690-169721	8	0.75
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	NZ_CP013856	Pseudonocardia sp. HH130630-07 plasmid pLS2-2, complete sequence	81256-81287	8	0.75
NZ_CP010221_1	1.9\|360650\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360650-360681	32	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	1036450-1036481	9	0.719
NZ_CP010221_1	1.9\|360650\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360650-360681	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1555010-1555041	9	0.719
NZ_CP010221_1	1.9\|360650\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360650-360681	32	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	619383-619414	9	0.719
NZ_CP010221_1	1.10\|360711\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360711-360742	32	NC_017140	Bacillus megaterium WSH-002 plasmid WSH-002_p2, complete sequence	5097-5128	9	0.719
NZ_CP010221_1	1.12\|360833\|32\|NZ_CP010221\|CRISPRCasFinder,CRT	360833-360864	32	MK249151	Blackfly microvirus SF02 isolate 049, complete genome	1908-1939	9	0.719
NZ_CP010221_2	2.1\|376424\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376424-376455	32	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	237562-237593	9	0.719
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MK618657	Klebsiella phage Sanco, complete genome	3481-3512	9	0.719
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MK931445	Klebsiella phage Shelby, complete genome	3301-3332	9	0.719
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_048043	Klebsiella phage NJS2, complete genome	4184-4215	9	0.719
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_028774	Klebsiella phage Sushi, complete genome	44600-44631	9	0.719
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	29844-29875	9	0.719
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NZ_CP036247	Enterococcus faecalis R712 plasmid pR712_01, complete sequence	74124-74155	9	0.719
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	14309-14340	9	0.719
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	97821-97852	9	0.719
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NZ_LR215032	Mycoplasma gallopavonis strain NCTC10186 plasmid 2	173597-173628	9	0.719
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NZ_CP027191	Lactobacillus sp. CBA3605 plasmid pCBA3605-1, complete sequence	35304-35335	9	0.719
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	NZ_CP010647	Phaeobacter piscinae strain P36 plasmid pP36_d, complete sequence	70883-70914	9	0.719
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	NZ_LN907828	Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence	312646-312677	9	0.719
NZ_CP010221_1	1.9\|360650\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360650-360681	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	823434-823465	10	0.688
NZ_CP010221_1	1.9\|360650\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360650-360681	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	682589-682620	10	0.688
NZ_CP010221_1	1.11\|360772\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360772-360803	32	NZ_CP039902	Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence	33041-33072	10	0.688
NZ_CP010221_1	1.11\|360772\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360772-360803	32	NZ_CP039893	Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence	217865-217896	10	0.688
NZ_CP010221_1	1.11\|360772\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360772-360803	32	NZ_KY000025	Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence	208000-208031	10	0.688
NZ_CP010221_1	1.11\|360772\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360772-360803	32	NZ_KY000029	Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence	208000-208031	10	0.688
NZ_CP010221_1	1.12\|360833\|32\|NZ_CP010221\|CRISPRCasFinder,CRT	360833-360864	32	NZ_CP038854	Pantoea vagans strain LMG 24199 plasmid unnamed1, complete sequence	450688-450719	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MH633486	Klebsiella phage NJS3, complete genome	3939-3970	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_049845	Klebsiella phage PhiKpNIH-2, complete genome	14022-14053	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_049842	Klebsiella phage vB_KpnS_15-38_KLPPOU149, complete genome	16218-16249	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	LR757892	Klebsiella phage vB_KpnS_2811 genome assembly, chromosome: 1	8256-8287	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MT894005	Klebsiella phage MMBB, complete genome	23405-23436	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MG552615	Klebsiella virus GML-KpCol1, complete genome	38176-38207	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	KP658157	Klebsiella phage 1513, complete genome	22763-22794	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MH633484	Klebsiella phage TAH8, complete genome	4134-4165	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MK931442	Klebsiella phage Sin4, complete genome	3944-3975	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MH844531	Klebsiella phage GH-K3, complete genome	45731-45762	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_048044	Klebsiella phage NJR15, complete genome	3972-4003	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_048143	Klebsiella phage KpKT21phi1, complete genome	32067-32098	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_049840	Klebsiella phage vB_KpnS_FZ10, complete genome	4384-4415	10	0.688
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_049844	Klebsiella phage 13, complete genome	27889-27920	10	0.688
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	HG796351	Uncultured bacterium plasmid pRGI00631	201-232	10	0.688
NZ_CP010221_2	2.4\|376607\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376607-376638	32	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	343912-343943	10	0.688
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	699305-699336	10	0.688
NZ_CP010221_2	2.6\|376729\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376729-376760	32	NC_015724	Cupriavidus necator N-1 plasmid pBB2, complete sequence	169020-169051	10	0.688
NZ_CP010221_1	1.3\|360284\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360284-360315	32	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	775203-775234	11	0.656
NZ_CP010221_1	1.3\|360284\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360284-360315	32	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	332045-332076	11	0.656
NZ_CP010221_1	1.3\|360284\|32\|NZ_CP010221\|CRISPRCasFinder,CRT,PILER-CR	360284-360315	32	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	184472-184503	11	0.656
NZ_CP010221_2	2.1\|376424\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376424-376455	32	NZ_CP041045	Paracoccus sp. AK26 plasmid pAK1, complete sequence	115785-115816	11	0.656
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	KY575286	UNVERIFIED: Klebsiella phage SH-Kp 160016, complete genome	19060-19091	11	0.656
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	MF415412	Klebsiella phage KPN N141, complete genome	16229-16260	11	0.656
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	JN672684	Enterobacteria phage F20, partial genome	46314-46345	11	0.656
NZ_CP010221_2	2.2\|376485\|32\|NZ_CP010221\|PILER-CR,CRISPRCasFinder,CRT	376485-376516	32	NC_049848	Klebsiella phage KP1801, complete genome	2979-3010	11	0.656

1. spacer 4.1|2218613|40|NZ_CP010221|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 2.8|376851|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MK972713 (Salmonella phage SW5, complete genome) position: , mismatch: 2, identity: 0.938

ccagcccttgttaacgtcttcgccgttcgggt	CRISPR spacer
ccagccgatgttaacgtcttcgccgttcgggt	Protospacer
******  ************************

3. spacer 2.8|376851|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MK972714 (Salmonella phage SW3, complete genome) position: , mismatch: 2, identity: 0.938

ccagcccttgttaacgtcttcgccgttcgggt	CRISPR spacer
ccagccgatgttaacgtcttcgccgttcgggt	Protospacer
******  ************************

4. spacer 2.8|376851|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_049460 (Salmonella phage SI7, complete genome) position: , mismatch: 2, identity: 0.938

ccagcccttgttaacgtcttcgccgttcgggt	CRISPR spacer
ccagccgatgttaacgtcttcgccgttcgggt	Protospacer
******  ************************

5. spacer 3.1|1590941|38|NZ_CP010221|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

6. spacer 2.1|376424|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 5, identity: 0.844

gcgcgcgactactgcccgacccgccgacaaca-	CRISPR spacer
gcgcgcgactacagcccgaccggccg-catcga	Protospacer
************ ******** **** ** *.

7. spacer 1.6|360467|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to MG592456 (Vibrio phage 1.081.O._10N.286.52.C2, partial genome) position: , mismatch: 6, identity: 0.812

attcttgatcacgcttttaccgaagt--aatggt	CRISPR spacer
attgttgatcacgcttttactgaagttcgacg--	Protospacer
*** ****************.*****  .*.*

8. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_017804 (Borreliella garinii BgVir plasmid lp54, complete sequence) position: , mismatch: 7, identity: 0.781

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
aaagtttaaaaaaaatcaagttcaaaaaattg	Protospacer
**  *.*..****** ***.************

9. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to CP022460 (Shigella sonnei strain 2015C-3807 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
accgcgccgcactggcgctggcgcggtcgatg	Protospacer
.*********************.****  ...

10. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015232 (Epibacterium mobile F1926 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
ggcgcgccgcaaaggcgctggcacggtctcgg	Protospacer
* *********  ************** *  .

11. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027555 (Epibacterium mobile isolate EPIB1 plasmid 3, complete sequence) position: , mismatch: 7, identity: 0.781

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
ggcgcgccgcaaaggcgctggcacggtctcgg	Protospacer
* *********  ************** *  .

12. spacer 1.9|360650|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP038236 (Leisingera sp. NJS201 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
tcgagcccgatcatcggcatcagcagttccgg	Protospacer
.**********.******** ***..* * *.

13. spacer 1.9|360650|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 8, identity: 0.75

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
tcgaccccgattatcgggatgagctcggcgtg	Protospacer
.*** ************ ******   *** .

14. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014203 (Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence) position: , mismatch: 8, identity: 0.75

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
tatgattggaaaaaaacaattttaaaaaataa	Protospacer
 **  .************* **.******* .

15. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_015254 (Brochothrix phage BL3, complete genome) position: , mismatch: 8, identity: 0.75

aatttctggaaaaaaacaaattca----aaaaattg	CRISPR spacer
aatttctcaaaaaaaacaaattcatcctgaag----	Protospacer
******* .***************    .**.

16. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 8, identity: 0.75

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
tcttgttttaaaaaaaataattcaaaaaattg	Protospacer
  ** .*  *******  **************

17. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010112 (Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-6, complete sequence) position: , mismatch: 8, identity: 0.75

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
aatcaatggaaaaaaccaaatacaaaaaacaa	Protospacer
***.  ********* ***** *******. .

18. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 8, identity: 0.75

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
aggagctacaaaaaaacaaattagaaaaattg	Protospacer
*.   **. ************* .********

19. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013856 (Pseudonocardia sp. HH130630-07 plasmid pLS2-2, complete sequence) position: , mismatch: 8, identity: 0.75

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
gcgtcgccgcactggcgctgacactgttcgtg	Protospacer
**  ****************.*** ** .*..

20. spacer 1.9|360650|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 9, identity: 0.719

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
tgaattaggattatcgacatgagcgatacgga	Protospacer
. .* .  ********.**********.****

21. spacer 1.9|360650|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 9, identity: 0.719

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gcgagcccgatcatcggcatgggcttcgagct	Protospacer
 **********.*********.**  .* *

22. spacer 1.9|360650|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 9, identity: 0.719

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gcgagcccgatcatcggcatgggcttcgagct	Protospacer
 **********.*********.**  .* *

23. spacer 1.10|360711|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NC_017140 (Bacillus megaterium WSH-002 plasmid WSH-002_p2, complete sequence) position: , mismatch: 9, identity: 0.719

tcgaagaagaaagggaaataatgcgaggaacg	CRISPR spacer
atggagaagaaagggaaacaaagcgagcgcgg	Protospacer
 .*.**************.** ***** .  *

24. spacer 1.12|360833|32|NZ_CP010221|CRISPRCasFinder,CRT matches to MK249151 (Blackfly microvirus SF02 isolate 049, complete genome) position: , mismatch: 9, identity: 0.719

cgcgagagccagcaaaacgccagggcacaaaa	CRISPR spacer
gccatgtcccaacaaaacgccagggaacaaat	Protospacer
  *. *  ***.************* *****

25. spacer 2.1|376424|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 9, identity: 0.719

gcgcgcgactactgcccgacccgccgacaaca	CRISPR spacer
accgccgactactgaccggcccgccgaccgaa	Protospacer
.*   ********* ***.********* . *

26. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MK618657 (Klebsiella phage Sanco, complete genome) position: , mismatch: 9, identity: 0.719

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaac	Protospacer
 *  ******** ******.*******  . *

27. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MK931445 (Klebsiella phage Shelby, complete genome) position: , mismatch: 9, identity: 0.719

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaac	Protospacer
 *  ******** ******.*******  . *

28. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_048043 (Klebsiella phage NJS2, complete genome) position: , mismatch: 9, identity: 0.719

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaac	Protospacer
 *  ******** ******.*******  . *

29. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_028774 (Klebsiella phage Sushi, complete genome) position: , mismatch: 9, identity: 0.719

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaac	Protospacer
 *  ******** ******.*******  . *

30. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 9, identity: 0.719

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
caacaaaagaaaaaaacagattcaaaaaaatg	Protospacer
 * .   .**********.********** **

31. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036247 (Enterococcus faecalis R712 plasmid pR712_01, complete sequence) position: , mismatch: 9, identity: 0.719

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
caacaaaagaaaaaaacagattcaaaaaaatg	Protospacer
 * .   .**********.********** **

32. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 9, identity: 0.719

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
tacgattggaaaaaaacaacctcaaaaaatgc	Protospacer
 *.  .************* .*********

33. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 9, identity: 0.719

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
tacgattggaaaaaaacaacctcaaaaaatgc	Protospacer
 *.  .************* .*********

34. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR215032 (Mycoplasma gallopavonis strain NCTC10186 plasmid 2) position: , mismatch: 9, identity: 0.719

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
taaaatggcaaaaaaagaaattcaaagaattg	Protospacer
 *   . * ******* *********.*****

35. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027191 (Lactobacillus sp. CBA3605 plasmid pCBA3605-1, complete sequence) position: , mismatch: 9, identity: 0.719

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
tgcctattgaaaaaaaaatattcaaaaaatta	Protospacer
 ...* * ******** * ************.

36. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010647 (Phaeobacter piscinae strain P36 plasmid pP36_d, complete sequence) position: , mismatch: 9, identity: 0.719

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
gctgcgccgccctggcgctggcaggctgcaag	Protospacer
**.******* ************ * *... .

37. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN907828 (Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence) position: , mismatch: 9, identity: 0.719

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
gcggcgcagcactggcgctggcagcaggcgta	Protospacer
** **** ***************  . ..*.*

38. spacer 1.9|360650|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gttgcggcgatcatcggcatgggcgatgcgta	Protospacer
 . .   ****.*********.******** *

39. spacer 1.9|360650|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 10, identity: 0.688

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gttgcggcgatcatcggcatgggcgatgcgta	Protospacer
 . .   ****.*********.******** *

40. spacer 1.11|360772|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039902 (Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

41. spacer 1.11|360772|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039893 (Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

42. spacer 1.11|360772|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY000025 (Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

43. spacer 1.11|360772|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY000029 (Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

44. spacer 1.12|360833|32|NZ_CP010221|CRISPRCasFinder,CRT matches to NZ_CP038854 (Pantoea vagans strain LMG 24199 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

cgcgagagccagcaaaacgccagggcacaaaa	CRISPR spacer
ggaaggagcctgcaaagcgccagggcaccggt	Protospacer
 * ..***** *****.*********** ..

45. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MH633486 (Klebsiella phage NJS3, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

46. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_049845 (Klebsiella phage PhiKpNIH-2, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

47. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_049842 (Klebsiella phage vB_KpnS_15-38_KLPPOU149, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

48. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to LR757892 (Klebsiella phage vB_KpnS_2811 genome assembly, chromosome: 1) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

49. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MT894005 (Klebsiella phage MMBB, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaat	Protospacer
 *  ******** ******.*******  . .

50. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MG552615 (Klebsiella virus GML-KpCol1, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

51. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to KP658157 (Klebsiella phage 1513, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaat	Protospacer
 *  ******** ******.*******  . .

52. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MH633484 (Klebsiella phage TAH8, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

53. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MK931442 (Klebsiella phage Sin4, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

54. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MH844531 (Klebsiella phage GH-K3, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaat	Protospacer
 *  ******** ******.*******  . .

55. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_048044 (Klebsiella phage NJR15, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaag	Protospacer
 *  ******** ******.*******  .

56. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_048143 (Klebsiella phage KpKT21phi1, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaat	Protospacer
 *  ******** ******.*******  . .

57. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_049840 (Klebsiella phage vB_KpnS_FZ10, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgaat	Protospacer
 *  ******** ******.*******  . .

58. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_049844 (Klebsiella phage 13, complete genome) position: , mismatch: 10, identity: 0.688

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
caaattgcccggttaagcagtggcgatcgagg	Protospacer
 *  ******** ******.*******  .

59. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to HG796351 (Uncultured bacterium plasmid pRGI00631) position: , mismatch: 10, identity: 0.688

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
cggctctgtaaaaaagcaaattcaaaaataca	Protospacer
 . .**** ******.************  ..

60. spacer 2.4|376607|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 10, identity: 0.688

aatttctggaaaaaaacaaattcaaaaaattg	CRISPR spacer
aggagttggaaaaaaataaaatcaaaaaaaga	Protospacer
*.   .**********.*** ********  .

61. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 10, identity: 0.688

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
tgcgcgccgaactggcggtggcacgcagcgag	Protospacer
  ******* ******* *******  ..* .

62. spacer 2.6|376729|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_015724 (Cupriavidus necator N-1 plasmid pBB2, complete sequence) position: , mismatch: 10, identity: 0.688

gccgcgccgcactggcgctggcacggtatgca	CRISPR spacer
tgcgcgccgaactggcggtggcacgcagcgag	Protospacer
  ******* ******* *******  ..* .

63. spacer 1.3|360284|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 11, identity: 0.656

gaacggcggctatacggattcgacaggtcagc	CRISPR spacer
acgacgcggctctccggattcgacaggttgat	Protospacer
. .  ****** * **************....

64. spacer 1.3|360284|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 11, identity: 0.656

gaacggcggctatacggattcgacaggtcagc	CRISPR spacer
acgacgcggctttccggattcgacaggttgat	Protospacer
. .  ****** * **************....

65. spacer 1.3|360284|32|NZ_CP010221|CRISPRCasFinder,CRT,PILER-CR matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 11, identity: 0.656

gaacggcggctatacggattcgacaggtcagc	CRISPR spacer
acgatgcggctttccggattcgacaggttgat	Protospacer
. .  ****** * **************....

66. spacer 2.1|376424|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041045 (Paracoccus sp. AK26 plasmid pAK1, complete sequence) position: , mismatch: 11, identity: 0.656

gcgcgcgactactgcccgacccgccgacaaca	CRISPR spacer
tacttttaccactgcccgactcgccgacaatc	Protospacer
   . . **.**********.*********.

67. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to KY575286 (UNVERIFIED: Klebsiella phage SH-Kp 160016, complete genome) position: , mismatch: 11, identity: 0.656

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
cgaattgcccggttaagcagtggcgatcgaag	Protospacer
 .  ******** ******.*******  .

68. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to MF415412 (Klebsiella phage KPN N141, complete genome) position: , mismatch: 11, identity: 0.656

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
cgaattgcccggttaagcagtggcgatcgaag	Protospacer
 .  ******** ******.*******  .

69. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to JN672684 (Enterobacteria phage F20, partial genome) position: , mismatch: 11, identity: 0.656

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
cgaattgcccggttaagcagtggcgatcgaag	Protospacer
 .  ******** ******.*******  .

70. spacer 2.2|376485|32|NZ_CP010221|PILER-CR,CRISPRCasFinder,CRT matches to NC_049848 (Klebsiella phage KP1801, complete genome) position: , mismatch: 11, identity: 0.656

gactttgcccggataagcaatggcgatacgtc	CRISPR spacer
cgaattgcccggttaagcagtggcgatcgaag	Protospacer
 .  ******** ******.*******  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

393265 : 400405

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001278994.1\|393265_393904_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590392.1\|393900_395163_-	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_000847985.1\|395159_396068_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_001297141.1\|396263_397031_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_001141314.1\|397081_397738_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	1.1e-50	47.9
WP_001272898.1\|397843_400405_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.3e-30	20.6

DBSCAN-SWA_2

783350 : 828291

Enterobacteria_phage(86.36%)

terminase,holin,head,tail,plate,tRNA,integrase,portal,capsid

attL 786779:786802|attR 832107:832130

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000683799.1\|783350_785357_-\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_000817178.1\|785515_786736_+	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
786779:786802	attL	NA	NA	NA	NA
WP_000127781.1\|787028_788207_+	MFS transporter	NA	NA	NA	NA
WP_000615821.1\|788203_789199_-	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_042094563.1\|789428_790220_-	site-specific DNA-methyltransferase	Q775B4	Bordetella_phage	7.4e-65	52.1
WP_042094562.1\|790164_790362_-	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000078920.1\|790597_790738_-	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	7.0e-19	100.0
WP_000488107.1\|790929_791190_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_000060706.1\|791274_792345_-	DUF4935 domain-containing protein	NA	NA	NA	NA
WP_000132808.1\|792517_793627_-	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	4.8e-195	94.6
WP_073519570.1\|793784_794969_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	6.4e-222	97.5
WP_000290450.1\|794968_795481_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	3.2e-93	100.0
WP_000665308.1\|795535_795901_+\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	3.8e-56	97.5
WP_000333495.1\|795909_796065_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	8.8e-23	100.0
WP_071685921.1\|796051_798859_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	88.2
WP_000979954.1\|798871_799360_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	1.6e-86	100.0
WP_001100987.1\|799456_800635_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_073519571.1\|800729_801329_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	5.9e-99	91.1
WP_047084517.1\|801328_803440_-\|tail	phage tail protein	A0A0A7NV63	Enterobacteria_phage	9.7e-112	97.7
WP_021293091.1\|803442_803973_-\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	5.1e-94	99.4
WP_001512968.1\|803965_804862_-\|plate	baseplate J/gp47 family protein	A0A0A7NPY5	Enterobacteria_phage	3.9e-155	98.0
WP_001067548.1\|804865_805195_-	GPW/gp25 family protein	A0A0A7NQ90	Enterobacteria_phage	2.2e-55	100.0
WP_077631957.1\|805212_805779_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	1.1e-99	97.9
WP_001705834.1\|805790_806426_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	9.0e-114	99.1
WP_000920594.1\|806418_806886_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	2.6e-86	100.0
WP_021511916.1\|807023_807431_-	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	7.7e-66	97.8
WP_000072335.1\|807427_807820_-	M15 family metallopeptidase	A0A0A7NQ86	Enterobacteria_phage	9.9e-71	99.2
WP_000104350.1\|807816_808140_-\|holin	phage holin family protein	A0A0A7NRY9	Enterobacteria_phage	1.6e-50	99.1
WP_000864897.1\|808142_808343_-\|tail	tail protein X	A0A0A7NV57	Enterobacteria_phage	6.0e-32	98.5
WP_000063094.1\|808342_808837_-\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	3.0e-88	98.2
WP_000632362.1\|808938_809739_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	1.3e-130	91.7
WP_021533064.1\|809784_810837_-\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	2.5e-193	97.1
WP_001262673.1\|810860_811697_-\|capsid	GPO family capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	2.7e-150	100.0
WP_000613781.1\|811851_813603_+	helix-turn-helix domain-containing protein	A0A0A7NV54	Enterobacteria_phage	0.0e+00	97.9
WP_001705841.1\|813602_814649_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	7.4e-206	99.7
WP_001289966.1\|815139_815730_-	ead/Ea22-like family protein	Q8HAA6	Salmonella_phage	3.6e-32	51.3
WP_000211289.1\|815793_816105_-	plasmid partitioning/stability family protein	A0A0A7NPT5	Enterobacteria_phage	1.2e-47	95.1
WP_000686499.1\|816109_817069_-	plasmid segregation protein ParM	A0A0A7NPX4	Enterobacteria_phage	2.0e-181	99.7
WP_021579107.1\|817145_819968_-	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	96.8
WP_073519572.1\|819974_820340_-	hypothetical protein	A0A0A7NRY1	Enterobacteria_phage	6.6e-61	96.7
WP_001326016.1\|820336_820954_-	ash family protein	S5MQL6	Escherichia_phage	5.3e-10	46.7
WP_021579106.1\|820965_821265_-	hypothetical protein	A0A0A7NRX6	Enterobacteria_phage	6.2e-41	90.8
WP_000153674.1\|821261_821507_-	winged helix-turn-helix domain-containing protein	A0A0A7NV47	Enterobacteria_phage	3.3e-40	98.8
WP_000985161.1\|821503_821707_-	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	2.9e-26	86.6
WP_000021652.1\|821792_821906_-	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	3.3e-11	97.3
WP_000514277.1\|821902_822145_-	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	2.3e-38	100.0
WP_044788547.1\|822156_822444_-	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	3.0e-32	75.8
WP_021579104.1\|822454_822796_-	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	2.5e-54	91.4
WP_073519573.1\|823048_823255_-	hypothetical protein	NA	NA	NA	NA
WP_000004249.1\|823261_823549_-	hypothetical protein	A0A0M4RCW1	Salmonella_phage	4.3e-23	52.6
WP_001390705.1\|823662_823983_+	helix-turn-helix transcriptional regulator	Q1JS37	Enterobacteria_phage	1.4e-14	43.2
WP_000023402.1\|824079_825084_+\|integrase	tyrosine-type recombinase/integrase	A0A0M4RTQ0	Salmonella_phage	4.5e-99	55.7
WP_000004833.1\|825242_826400_+	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	7.9e-23	29.1
WP_001289162.1\|826465_827479_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_001283590.1\|827478_828291_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
832107:832130	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1035036 : 1044478

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569329.1\|1035036_1035963_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	2.8e-23	30.8
WP_000783120.1\|1035967_1036699_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|1036679_1036787_-	protein YohO	NA	NA	NA	NA
WP_001240401.1\|1036846_1037578_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|1037799_1039485_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|1039481_1040201_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295430.1\|1040247_1040718_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_001295429.1\|1040758_1041220_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001317947.1\|1041344_1043345_-	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.1
WP_001292774.1\|1043341_1044478_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7

DBSCAN-SWA_4

1369432 : 1454125

100

Escherichia_phage(44.07%)

terminase,holin,head,integrase,tail,tRNA,portal,lysis,capsid,protease,transposase

attL 1371187:1371202|attR 1403840:1403855

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000916763.1\|1369432_1369663_-	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.3e-14	61.8
WP_000204699.1\|1369801_1370176_+	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_000879280.1\|1370179_1371052_+	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_000976492.1\|1371064_1371406_+	YebY family protein	NA	NA	NA	NA
1371187:1371202	attL	NA	NA	NA	NA
WP_001189091.1\|1371798_1372875_-\|integrase	phage integrase Arm DNA-binding domain-containing protein	A0A2H4IYC8	uncultured_Caudovirales_phage	5.3e-98	51.7
WP_001311878.1\|1372840_1373122_-	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.7e-11	41.2
WP_001356607.1\|1373228_1373417_-	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	1.6e-18	97.9
WP_042853000.1\|1373409_1373604_-	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	7.6e-32	96.9
WP_000166317.1\|1373660_1374470_-	recombination protein RecT	A0A1P8DTF2	Proteus_phage	6.8e-106	71.5
WP_021527613.1\|1374462_1377096_-	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	2.9e-206	58.1
WP_001452559.1\|1377194_1377470_-	hypothetical protein	A0A0U2QW85	Escherichia_phage	3.7e-40	92.3
WP_000245528.1\|1377544_1377721_-	hypothetical protein	A0A0U2SHB5	Escherichia_phage	9.7e-26	93.1
WP_073519610.1\|1377714_1377936_-	cell division protein FtsZ	A0A0U2RTC4	Escherichia_phage	1.3e-35	93.2
WP_001419881.1\|1378465_1378660_+	hypothetical protein	NA	NA	NA	NA
WP_000232638.1\|1378625_1378844_-	hypothetical protein	NA	NA	NA	NA
WP_000410105.1\|1379143_1379563_-	helix-turn-helix domain-containing protein	K7PH71	Enterobacterial_phage	3.1e-14	60.6
WP_001033914.1\|1379659_1379902_+	helix-turn-helix transcriptional regulator	K7PKH4	Enterobacteria_phage	2.3e-17	62.1
WP_000702025.1\|1379898_1380321_+	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	3.4e-69	94.3
WP_073519611.1\|1380398_1381529_+	hypothetical protein	G9L6A8	Escherichia_phage	2.5e-42	65.5
WP_073519612.1\|1381535_1382282_+	ATP-binding protein	V5UQI5	Shigella_phage	2.1e-114	80.9
WP_073519613.1\|1382304_1383066_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.8e-117	88.1
WP_073519614.1\|1383081_1383504_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	6.3e-63	91.2
WP_073519615.1\|1383500_1383701_+	hypothetical protein	K7P729	Enterobacteria_phage	7.9e-16	71.2
WP_073528026.1\|1384222_1384480_+	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	1.8e-28	88.9
WP_073519448.1\|1384584_1385604_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_073519617.1\|1385884_1386403_+	DUF551 domain-containing protein	V5UT79	Shigella_phage	6.8e-35	48.8
WP_073519618.1\|1386399_1386795_+	hypothetical protein	A0A193GYM6	Enterobacter_phage	2.3e-38	62.8
WP_000018421.1\|1387028_1387241_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	8.1e-27	92.9
WP_000119355.1\|1387449_1387629_+	hypothetical protein	NA	NA	NA	NA
WP_000818163.1\|1387647_1388133_+	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_000411312.1\|1388356_1388569_+	hypothetical protein	NA	NA	NA	NA
WP_061892354.1\|1388640_1389240_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.7e-106	93.0
WP_073519620.1\|1389239_1389530_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	1.3e-46	88.5
WP_073519621.1\|1389526_1390069_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	6.4e-76	75.7
WP_073519622.1\|1391643_1392072_+	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_064768310.1\|1393538_1393844_+	DUF826 domain-containing protein	NA	NA	NA	NA
WP_000284506.1\|1393921_1394137_+\|holin	class II holin family protein	Q9ZWW2	Enterobacteria_phage	6.9e-34	100.0
WP_073519623.1\|1394140_1394692_+	YdfR family protein	Q08JA0	Stx2-converting_phage	1.1e-43	58.9
WP_073519624.1\|1394639_1394900_-	hypothetical protein	NA	NA	NA	NA
WP_061892325.1\|1395014_1395548_+	lysozyme	K7PLY1	Enterobacteria_phage	6.4e-97	94.4
WP_061892324.1\|1395544_1396012_+\|lysis	lysis protein	K7PH77	Enterobacteria_phage	7.2e-76	98.7
WP_061892323.1\|1395999_1396152_+	hypothetical protein	K7PKL2	Enterobacteria_phage	1.2e-19	94.0
WP_073528025.1\|1396463_1396856_-	DUF1398 family protein	NA	NA	NA	NA
WP_061892169.1\|1397571_1398120_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	6.5e-60	86.3
WP_073519627.1\|1398091_1400020_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	3.1e-258	66.2
WP_061892171.1\|1400003_1400207_+\|tail	phage tail protein	K7PM10	Enterobacteria_phage	9.5e-09	55.7
WP_061892172.1\|1400203_1401796_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	3.4e-186	61.5
WP_073519628.1\|1401785_1403291_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	2.9e-102	54.4
WP_061892174.1\|1403327_1403675_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.2e-21	57.0
WP_073519629.1\|1403732_1404761_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	5.9e-115	61.9
1403840:1403855	attR	NA	NA	NA	NA
WP_061892713.1\|1404813_1405194_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	7.2e-34	70.0
WP_073519630.1\|1405205_1405559_+\|head,tail	head-tail joining protein	A0A2R9YJJ5	Escherichia_phage	2.4e-60	95.7
WP_061892715.1\|1405570_1406146_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	9.8e-51	60.2
WP_061892716.1\|1406142_1406538_+\|tail	phage tail protein	A0A2R9YJI2	Escherichia_phage	1.7e-65	92.4
WP_061892718.1\|1406545_1407286_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	5.2e-129	97.2
WP_053294703.1\|1407301_1407724_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	1.7e-60	85.7
WP_073519631.1\|1407705_1408140_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	2.7e-61	94.2
WP_073519632.1\|1408132_1410712_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	96.7
WP_021528540.1\|1410708_1411038_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	2.1e-53	93.6
WP_001152619.1\|1411037_1411736_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	7.3e-133	99.1
WP_073519633.1\|1411741_1412485_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.2e-146	96.4
WP_073521376.1\|1413115_1416529_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	95.9
WP_001233071.1\|1416599_1417199_+	Ail/Lom family outer membrane beta-barrel protein	A0A291AWV3	Escherichia_phage	4.4e-110	98.5
WP_077898616.1\|1417263_1418433_+\|tail	prophage tail fiber N-terminal domain-containing protein	Q9LA62	Enterobacterial_phage	1.4e-32	64.1
WP_077897937.1\|1418416_1418983_+	DUF4376 domain-containing protein	S5MBX6	Escherichia_phage	1.8e-28	42.2
WP_061892726.1\|1418975_1419359_+	DUF1353 domain-containing protein	A0A0A8J9K3	Ralstonia_phage	1.3e-14	41.1
WP_077897940.1\|1419644_1419827_+	DUF1353 domain-containing protein	NA	NA	NA	NA
WP_000812724.1\|1421726_1422383_+	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	3.1e-56	50.2
WP_001296140.1\|1422383_1422575_-	YebW family protein	NA	NA	NA	NA
WP_001295499.1\|1422679_1422916_-	DUF1480 family protein	NA	NA	NA	NA
WP_000057022.1\|1423033_1424473_-	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_001299674.1\|1424552_1427186_-	lipid-binding membrane homeostasis protein YebT	NA	NA	NA	NA
WP_001207284.1\|1427154_1428438_-	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_073519635.1\|1428567_1429065_+	L-methionine (R)-S-oxide reductase	NA	NA	NA	NA
WP_000431370.1\|1429161_1429860_+	RNA chaperone ProQ	NA	NA	NA	NA
WP_001326055.1\|1429879_1431928_+	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	1.2e-85	33.3
WP_000984517.1\|1432119_1433001_+\|protease	protease HtpX	NA	NA	NA	NA
WP_001127216.1\|1433046_1434420_-	MFS transporter	NA	NA	NA	NA
WP_001262174.1\|1434596_1435388_+	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
WP_001211011.1\|1435530_1435770_-	hypothetical protein	NA	NA	NA	NA
WP_000714550.1\|1435928_1436072_+	PhoP/PhoQ regulator MgrB	NA	NA	NA	NA
WP_001006865.1\|1436146_1436434_+	YebO family protein	NA	NA	NA	NA
WP_001295496.1\|1437103_1437247_+	YobF family protein	NA	NA	NA	NA
WP_001062678.1\|1437259_1437469_+	transcription antiterminator/RNA stability regulator CspE	A0A1W6JNX5	Morganella_phage	1.6e-22	78.1
WP_000010129.1\|1437634_1438444_+	23S rRNA (guanine(745)-N(1))-methyltransferase	NA	NA	NA	NA
WP_001296134.1\|1438440_1439007_-	manganese efflux pump MntP	NA	NA	NA	NA
WP_073519636.1\|1439436_1439895_-	DUF986 domain-containing protein	NA	NA	NA	NA
WP_000228655.1\|1439949_1440801_-	PTS mannose transporter subunit IID	NA	NA	NA	NA
WP_000406926.1\|1440813_1441614_-	PTS mannose transporter subunit IIC	NA	NA	NA	NA
WP_000150543.1\|1441676_1442648_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_053898130.1\|1443110_1444667_+	CNNM family cation transport protein YoaE	A0A0R6PEZ3	Moraxella_phage	6.0e-42	45.8
WP_001295494.1\|1444670_1446269_-	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
WP_000624298.1\|1446399_1447764_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_000456725.1\|1447947_1448526_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_000854972.1\|1448529_1449891_-	aminodeoxychorismate synthase component 1	S4VT78	Pandoravirus	3.4e-41	33.4
WP_000457334.1\|1449964_1450144_+	YoaH family protein	NA	NA	NA	NA
WP_001307845.1\|1450263_1450623_-	DUF1889 family protein	NA	NA	NA	NA
WP_001295493.1\|1450985_1451330_-	RidA family protein	NA	NA	NA	NA
WP_000128847.1\|1451461_1453372_+	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	4.5e-92	31.9
WP_001220965.1\|1453429_1454125_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA

DBSCAN-SWA_5

2260888 : 2308221

Escherichia_phage(52.08%)

terminase,head,holin,tail,integrase,portal,lysis,capsid,protease

attL 2306075:2306090|attR 2308906:2308921

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000003671.1\|2260888_2261476_-\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA
WP_073519691.1\|2261472_2262180_-	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_001504149.1\|2262198_2263992_-	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_001058323.1\|2263988_2265107_-	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_073519868.1\|2266673_2267057_-	DUF1353 domain-containing protein	A0A0A8J9K3	Ralstonia_phage	3.4e-15	42.1
WP_077897937.1\|2267049_2267616_-	DUF4376 domain-containing protein	S5MBX6	Escherichia_phage	1.8e-28	42.2
WP_073519693.1\|2268834_2269434_-	Ail/Lom family outer membrane beta-barrel protein	H6WZM8	Escherichia_phage	9.4e-105	93.0
WP_073519694.1\|2269501_2272885_-	host specificity protein J	A0A0K2FI38	Escherichia_phage	0.0e+00	87.0
WP_073519695.1\|2272945_2273581_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.7e-83	74.9
WP_073519869.1\|2273478_2274222_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	6.8e-145	93.9
WP_073519696.1\|2274227_2274926_-\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	2.4e-131	96.6
WP_001330090.1\|2274925_2275282_-\|tail	phage tail protein	A0A0P0ZDL9	Stx2-converting_phage	2.8e-40	66.7
WP_073519697.1\|2275259_2278487_-\|tail	phage tail tape measure protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	93.5
WP_059215648.1\|2278533_2278812_-	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	1.8e-42	96.7
WP_016231754.1\|2278835_2279207_-\|tail	phage tail assembly chaperone	A0A1B5FP91	Escherichia_phage	5.2e-61	95.9
WP_059215647.1\|2279221_2279926_-	hypothetical protein	A0A1B5FP82	Escherichia_phage	1.9e-117	95.7
WP_073519698.1\|2279986_2280331_-	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	8.8e-55	96.5
WP_172944233.1\|2280327_2280774_-	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	8.7e-63	79.7
WP_001147815.1\|2280773_2281112_-\|head	phage head closure protein	A0A1B5FP90	Escherichia_phage	1.2e-51	91.1
WP_065228207.1\|2281120_2281438_-\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	4.8e-23	51.5
WP_073519700.1\|2281482_2282709_-\|capsid	phage major capsid protein	Q8W627	Enterobacteria_phage	1.1e-187	99.1
WP_001193625.1\|2282722_2283373_-\|head,protease	HK97 family phage prohead protease	Q8W628	Enterobacteria_phage	6.0e-121	100.0
WP_073519701.1\|2283350_2284592_-\|portal	phage portal protein	Q8W629	Enterobacteria_phage	3.6e-231	94.7
WP_069904030.1\|2284591_2284774_-	hypothetical protein	A0A1B5FP99	Escherichia_phage	4.8e-20	81.7
WP_001140897.1\|2284785_2286543_-\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	0.0e+00	99.5
WP_038354741.1\|2286542_2287025_-\|terminase	phage terminase small subunit P27 family	A0A1B5FPA0	Escherichia_phage	2.7e-86	99.4
WP_001140099.1\|2287171_2287522_-	HNH endonuclease	A0A1B5FP94	Escherichia_phage	1.2e-64	98.3
WP_073519702.1\|2287529_2287730_-	hypothetical protein	NA	NA	NA	NA
WP_073519703.1\|2287816_2288119_-	hypothetical protein	Q8HA83	Salmonella_phage	3.8e-46	86.0
WP_001542813.1\|2288201_2288498_-	hypothetical protein	Q8W634	Enterobacteria_phage	1.5e-50	98.0
WP_164997238.1\|2288672_2288828_-	hypothetical protein	NA	NA	NA	NA
WP_073519704.1\|2288869_2289247_-	M15 family metallopeptidase	Q9MBZ3	Enterobacteria_phage	2.5e-63	96.8
WP_073519705.1\|2289249_2289525_-\|holin	phage holin family protein	A0A0U2SHD1	Escherichia_phage	1.7e-40	92.3
WP_001351476.1\|2289514_2289907_-\|holin	holin	Q8W636	Enterobacteria_phage	1.0e-54	96.9
WP_073519706.1\|2291184_2291874_-	antiterminator	I6PDF8	Cronobacter_phage	1.4e-59	50.2
WP_073519707.1\|2291870_2292230_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.4e-39	68.4
WP_073519708.1\|2292242_2293289_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	5.0e-109	55.0
WP_073519709.1\|2293581_2293842_-	hypothetical protein	NA	NA	NA	NA
WP_073519710.1\|2294062_2294275_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	5.1e-21	84.3
WP_073519711.1\|2294486_2294882_-	hypothetical protein	A0A193GYM6	Enterobacter_phage	1.6e-36	60.5
WP_073519712.1\|2294881_2295547_-	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	1.0e-51	48.9
WP_073519713.1\|2295543_2295753_-	hypothetical protein	A0A0F6TJE4	Escherichia_coli_O157_typing_phage	3.7e-32	91.3
WP_172944234.1\|2295754_2296060_-	hypothetical protein	A0A076GCN9	Escherichia_phage	4.3e-37	78.9
WP_073519714.1\|2296268_2296871_-	ead/Ea22-like family protein	A0A0F6R7P8	Escherichia_coli_O157_typing_phage	3.1e-55	72.3
WP_000753060.1\|2296867_2297044_-	hypothetical protein	A0A2R2X2A8	Escherichia_phage	6.7e-27	94.8
WP_172944232.1\|2297045_2297219_-	hypothetical protein	A0A2R2Z308	Escherichia_phage	5.2e-24	94.7
WP_077897935.1\|2297311_2297668_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.4e-58	99.2
WP_073519871.1\|2297725_2298121_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.4e-32	54.3
WP_157896686.1\|2298150_2298693_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.5e-85	98.7
WP_123006575.1\|2298604_2299645_-	DNA-binding protein	A0A0U2RT81	Escherichia_phage	1.0e-90	87.2
WP_073519717.1\|2299616_2300168_-	hypothetical protein	NA	NA	NA	NA
WP_000476986.1\|2300151_2300379_-	transcriptional regulator	NA	NA	NA	NA
WP_001003379.1\|2300456_2300864_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	7.2e-24	45.4
WP_073519718.1\|2301114_2301414_+	hypothetical protein	NA	NA	NA	NA
WP_001171942.1\|2301485_2301704_+	hypothetical protein	NA	NA	NA	NA
WP_073519719.1\|2301726_2302134_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	3.0e-09	40.0
WP_000920491.1\|2302111_2302345_-	hypothetical protein	NA	NA	NA	NA
WP_000449196.1\|2302906_2303095_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_073519720.1\|2303091_2303283_+\|lysis	lysis protein YdfD	NA	NA	NA	NA
WP_073519721.1\|2303376_2305848_+	exonuclease	A0A192Y6E0	Salmonella_phage	2.2e-59	59.1
WP_021564129.1\|2305914_2306166_+	DUF4224 domain-containing protein	NA	NA	NA	NA
2306075:2306090	attL	NA	NA	NA	NA
WP_073519722.1\|2306134_2307154_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	4.9e-85	49.4
WP_000375136.1\|2307561_2308221_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	4.0e-48	55.3
2308906:2308921	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3074024 : 3079338

Stx2-converting_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073519772.1\|3074024_3075596_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.4e-168	59.1
WP_000624622.1\|3075615_3075963_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_073519873.1\|3075962_3076610_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.5e-20	45.2
WP_000410600.1\|3076677_3077184_+	helix-turn-helix domain-containing protein	A0A1B1P776	Bacillus_phage	2.5e-10	32.5
WP_172944258.1\|3077159_3078023_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.0e-75	51.3
WP_049590476.1\|3078546_3079338_-	BRO family, N-terminal domain protein	Q6J1W3	Lactobacillus_phage	3.7e-08	31.3

DBSCAN-SWA_7

3769449 : 3827822

Pectobacterium_phage(11.11%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000312488.1\|3769449_3770709_+\|protease	FtsH protease activity modulator HflK	A0A1L2CVV0	Pectobacterium_phage	3.6e-05	25.5
WP_001232412.1\|3770711_3771716_+\|protease	protease modulator HflC	NA	NA	NA	NA
WP_001089295.1\|3771797_3771995_+	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_000527955.1\|3772098_3773397_+	adenylosuccinate synthase	W5S5V7	Pithovirus	2.2e-66	35.9
WP_001177639.1\|3773601_3774027_+	nitric oxide-sensing transcriptional repressor NsrR	NA	NA	NA	NA
WP_000076316.1\|3774065_3776507_+	ribonuclease R	Q0GXV6	Lactococcus_phage	6.4e-67	33.1
WP_001293282.1\|3776686_3777418_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000220137.1\|3777544_3777946_+	DUF2170 family protein	NA	NA	NA	NA
WP_000511955.1\|3777964_3778663_+	PspA/IM30 family protein	NA	NA	NA	NA
WP_000012553.1\|3778713_3779373_+	YjfK family protein	NA	NA	NA	NA
WP_000547760.1\|3779390_3779789_+	DUF350 domain-containing protein	NA	NA	NA	NA
WP_000101649.1\|3779798_3780437_+	DUF1190 domain-containing protein	NA	NA	NA	NA
WP_000943987.1\|3780439_3781603_+	glutathionylspermidine synthase family protein	B2ZXR7	Ralstonia_phage	1.7e-81	43.5
WP_001339483.1\|3781686_3783312_+	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_000811566.1\|3783428_3783704_-\|protease	protease activator YjfN	NA	NA	NA	NA
WP_000254636.1\|3783852_3784182_-	biofilm peroxide resistance protein BsmA	NA	NA	NA	NA
WP_000569708.1\|3784363_3785113_+	esterase	NA	NA	NA	NA
WP_000133631.1\|3785109_3785865_-	HTH-type transcriptional regulator UlaR	NA	NA	NA	NA
WP_001295191.1\|3785972_3787037_-	L-ascorbate 6-phosphate lactonase	NA	NA	NA	NA
WP_001300695.1\|3787391_3788789_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_000218358.1\|3788804_3789110_+	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
WP_000776505.1\|3789119_3789584_+	PTS ascorbate transporter subunit IIA	NA	NA	NA	NA
WP_000056760.1\|3789597_3790248_+	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	NA	NA	NA	NA
WP_000949539.1\|3790257_3791112_+	L-ribulose-5-phosphate 3-epimerase UlaE	NA	NA	NA	NA
WP_001170812.1\|3791111_3791798_+	L-ribulose-5-phosphate 4-epimerase UlaF	NA	NA	NA	NA
WP_000996728.1\|3791894_3792446_+	DUF1440 domain-containing protein	NA	NA	NA	NA
WP_000492914.1\|3792520_3792796_-	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_001216676.1\|3793122_3793518_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_001296681.1\|3793524_3793839_+	primosomal replication protein N	NA	NA	NA	NA
WP_000135199.1\|3793843_3794071_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_001196062.1\|3794112_3794562_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_001351393.1\|3794632_3795427_-	DUF2686 family protein	NA	NA	NA	NA
WP_000604912.1\|3796049_3796481_-\|transposase	IS200/IS605-like element IS609 family transposase	A0A1S5RHE3	Helicobacter_phage	1.9e-43	60.6
WP_000826425.1\|3796488_3797697_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	9.2e-208	93.0
WP_001119478.1\|3797831_3798470_-	cell division protein YtfB	NA	NA	NA	NA
WP_000211225.1\|3798688_3799309_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_000228346.1\|3799617_3801030_+	D-serine/D-alanine/glycine transporter	NA	NA	NA	NA
WP_000331456.1\|3801074_3801737_-	iron-sulfur cluster repair protein YtfE	NA	NA	NA	NA
WP_073519817.1\|3801844_3802810_-	DMT family transporter	NA	NA	NA	NA
WP_000560563.1\|3802917_3803778_-	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_073519816.1\|3803866_3804247_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000886909.1\|3806507_3807248_+	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_000175289.1\|3807237_3807795_-	YtfJ family protein	NA	NA	NA	NA
WP_000689228.1\|3808119_3808326_+	DUF1107 domain-containing protein	NA	NA	NA	NA
WP_000935042.1\|3808387_3809731_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001295196.1\|3810053_3810692_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_001269327.1\|3810897_3812631_+	autotransporter assembly complex protein TamA	NA	NA	NA	NA
WP_000060945.1\|3812627_3816407_+	autotransporter assembly complex protein TamB	NA	NA	NA	NA
WP_001219160.1\|3816409_3816751_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_001223208.1\|3816962_3817214_+	type II toxin-antitoxin system antitoxin ChpS	NA	NA	NA	NA
WP_000239579.1\|3817207_3817558_+	endoribonuclease toxin ChpB	NA	NA	NA	NA
WP_000055075.1\|3817637_3818168_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	1.2e-55	63.3
WP_000265933.1\|3818477_3819434_+	galactofuranose ABC transporter substrate-binding protein YtfQ	NA	NA	NA	NA
WP_000205813.1\|3819573_3821076_+	sugar ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.4e-11	30.3
WP_001296689.1\|3821089_3822112_+	ABC transporter permease	NA	NA	NA	NA
WP_000596015.1\|3822098_3823094_+	sugar ABC transporter permease YjfF	NA	NA	NA	NA
WP_000853753.1\|3823126_3824125_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	5.7e-70	42.7
WP_001219792.1\|3824300_3825674_+	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	NA	NA	NA	NA
WP_000166270.1\|3825824_3826376_-	ribosome-associated protein	NA	NA	NA	NA
WP_001162171.1\|3826469_3827822_+\|protease	metalloprotease PmbA	NA	NA	NA	NA

DBSCAN-SWA_8

3871207 : 3881688

Enterobacteria_phage(80.0%)

integrase

attL 3862817:3862831|attR 3891802:3891816

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3862817:3862831	attL	NA	NA	NA	NA
WP_000446132.1\|3871207_3871780_-	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	2.2e-95	97.3
WP_000638629.1\|3871853_3872354_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_024215847.1\|3872350_3873085_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	7.4e-128	97.1
WP_001149160.1\|3873637_3873904_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_032226384.1\|3873900_3874455_+	ash family protein	Q7M2A7	Enterobacteria_phage	4.0e-41	80.2
WP_001244665.1\|3874447_3874735_+	hypothetical protein	Q7M2A0	Enterobacteria_phage	8.6e-48	97.9
WP_000459291.1\|3874727_3875183_+	hypothetical protein	Q7M298	Enterobacteria_phage	1.6e-64	99.1
WP_073519814.1\|3875318_3875639_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_001544037.1\|3875653_3877987_+	toprim domain-containing protein	Q7M2A8	Enterobacteria_phage	0.0e+00	98.7
WP_170979708.1\|3878312_3878537_+\|integrase	integrase	Q38404	Enterobacteria_phage	9.8e-23	96.1
WP_001218329.1\|3878752_3880018_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.1e-81	43.1
WP_001022619.1\|3880218_3881688_-	serine/threonine protein kinase	A0A2K9L5Y0	Tupanvirus	1.4e-11	26.5
3891802:3891816	attR	NA	NA	NA	NA

DBSCAN-SWA_9

4286600 : 4353498

Stx2-converting_phage(38.89%)

tRNA,integrase,protease,transposase

attL 4339182:4339197|attR 4365694:4365709

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001445629.1\|4286600_4287029_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_073519782.1\|4287371_4287830_-	hypothetical protein	NA	NA	NA	NA
WP_001298267.1\|4289368_4290151_-	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_000350265.1\|4290455_4291376_+	ribokinase	NA	NA	NA	NA
WP_000998352.1\|4291403_4292720_+	L-fucose:H+ symporter permease	NA	NA	NA	NA
WP_001533773.1\|4294167_4294452_+\|transposase	transposase	Q6H9S5	Enterobacteria_phage	1.0e-24	62.2
WP_000345349.1\|4294667_4295924_-	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_000705927.1\|4295936_4296224_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_000916811.1\|4296239_4296683_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_000416158.1\|4296953_4297985_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	1.4e-18	27.0
WP_073519781.1\|4298739_4299363_+	DNA-binding protein	NA	NA	NA	NA
WP_073519780.1\|4299584_4301357_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	A0A0R6PI85	Moraxella_phage	6.0e-22	25.5
WP_073521398.1\|4301369_4311146_+\|tRNA	contact-dependent inhibition effector tRNA nuclease	A0A0R6PJK4	Moraxella_phage	7.3e-29	36.9
WP_000826005.1\|4311142_4311376_+	hypothetical protein	NA	NA	NA	NA
WP_073519403.1\|4312479_4314051_-\|transposase	IS66-like element ISCro1 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.2e-167	58.3
WP_012904570.1\|4314070_4314418_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	3.4e-46	76.6
WP_073519844.1\|4314417_4315065_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.1e-21	46.0
WP_000410600.1\|4315132_4315639_+	helix-turn-helix domain-containing protein	A0A1B1P776	Bacillus_phage	2.5e-10	32.5
WP_172944258.1\|4315614_4316478_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.0e-75	51.3
WP_077897958.1\|4316559_4316787_+	autotransporter outer membrane beta-barrel domain-containing protein	A0A2L1IV18	Escherichia_phage	2.8e-17	51.4
WP_073519404.1\|4316940_4318239_-	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_073519405.1\|4318300_4319020_-	amino acid racemase	NA	NA	NA	NA
WP_073519406.1\|4319360_4320293_+	hypochlorite stress DNA-binding transcriptional regulator HypT	NA	NA	NA	NA
WP_172944248.1\|4320295_4320559_+	hypothetical protein	NA	NA	NA	NA
WP_073519407.1\|4320927_4321197_+	hypothetical protein	NA	NA	NA	NA
WP_149025688.1\|4321549_4322712_-\|transposase	IS3-like element IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	4.0e-51	40.6
WP_077897957.1\|4326431_4327187_+	hypothetical protein	NA	NA	NA	NA
WP_073519410.1\|4327150_4327504_+	hypothetical protein	NA	NA	NA	NA
WP_073519411.1\|4327564_4327951_+	CaiF/GrlA family transcriptional regulator	NA	NA	NA	NA
WP_001323403.1\|4329698_4330478_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-139	100.0
WP_061892120.1\|4332582_4332930_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	8.2e-61	99.1
WP_073519847.1\|4332926_4333307_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.9e-58	90.5
WP_077875792.1\|4333744_4335400_+	YadA-like family protein	NA	NA	NA	NA
WP_061892122.1\|4335670_4335895_+	hypothetical protein	NA	NA	NA	NA
WP_073519414.1\|4336366_4336882_-	hypothetical protein	NA	NA	NA	NA
WP_077897956.1\|4337168_4341950_+	autotransporter outer membrane beta-barrel domain-containing protein	A0A2L1IV18	Escherichia_phage	9.4e-155	39.7
4339182:4339197	attL	NA	NA	NA	NA
WP_073542044.1\|4342237_4342588_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	4.7e-48	86.1
WP_172944249.1\|4342613_4342814_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.1e-24	83.1
WP_073519416.1\|4343543_4344320_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_073519417.1\|4344656_4344890_-	response regulator transcription factor	NA	NA	NA	NA
WP_061892129.1\|4346330_4346762_-	superinfection exclusion B family protein	NA	NA	NA	NA
WP_077875793.1\|4347876_4348134_+	DUF1353 domain-containing protein	NA	NA	NA	NA
WP_073519419.1\|4349944_4350781_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_021537648.1\|4352316_4353498_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.1e-162	69.7
4365694:4365709	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP010222

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP010221

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection