CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP018448	Klebsiella pneumoniae strain Kp_Goe_33208 plasmid pKp_Goe_208-1, complete sequence	0 crisprs	RT	0	0	1
NZ_CP018447	Klebsiella pneumoniae strain Kp_Goe_33208 chromosome, complete genome	4 crisprs	csa3,RT,cas3,DEDDh,DinG,WYL	2	1	9
NZ_CP018449	Klebsiella pneumoniae strain Kp_Goe_33208 plasmid pKp_Goe_208-2, complete sequence	0 crisprs	NA	0	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4548 : 72078

Escherichia_phage(33.33%)

integrase,transposase

attL 6274:6333|attR 78982:79803

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000227969.1\|4548_5625_+\|transposase	IS110 family transposase	NA	NA	NA	NA
6274:6333	attL	NA	NA	NA	NA
WP_001067855.1\|6337_7042_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000842134.1\|7531_8641_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.8e-33	30.2
WP_001039466.1\|8735_9920_-	tetracycline efflux MFS transporter Tet(D)	NA	NA	NA	NA
WP_023352616.1\|10015_10624_+	tetracycline resistance transcriptional repressor TetR(D)	NA	NA	NA	NA
WP_001067855.1\|10670_11375_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001039463.1\|12137_12524_+	hypothetical protein	NA	NA	NA	NA
WP_000861580.1\|12532_12724_+	hypothetical protein	NA	NA	NA	NA
WP_000807690.1\|13735_14491_+	replication initiation protein RepE	I3WF20	Macacine_betaherpesvirus	4.5e-136	96.0
WP_011977766.1\|15908_16244_-	C2H2-type zinc finger protein	NA	NA	NA	NA
WP_001568067.1\|16416_16698_+	hypothetical protein	NA	NA	NA	NA
WP_000176305.1\|16751_17363_+	DUF2913 family protein	NA	NA	NA	NA
WP_011977825.1\|17359_17521_-	hypothetical protein	NA	NA	NA	NA
WP_001145103.1\|17547_18540_-	hypothetical protein	NA	NA	NA	NA
WP_000075580.1\|18588_18744_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|18884_19589_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001137892.1\|19644_20229_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000004159.1\|20228_21467_-	MFS transporter	NA	NA	NA	NA
WP_000219391.1\|21463_22369_-	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_001067855.1\|22490_23195_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000993386.1\|23267_23504_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001300294.1\|23539_24208_+	EAL domain-containing protein	NA	NA	NA	NA
WP_000027057.1\|26118_26979_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_000722315.1\|27678_28503_-	oxacillin-hydrolyzing class D beta-lactamase OXA-9	NA	NA	NA	NA
WP_001206315.1\|28562_29351_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
WP_000095725.1\|29443_30703_-	chloramphenicol efflux MFS transporter CmlA1	S4TR35	Salmonella_phage	4.8e-26	31.7
WP_001261740.1\|30964_31756_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_000050382.1\|31813_32422_-	HAD-IB family hydrolase	NA	NA	NA	NA
WP_001456218.1\|32517_33360_-	alpha/beta fold putative hydrolase EstX	NA	NA	NA	NA
WP_000845048.1\|33526_34540_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_000454193.1\|34742_35093_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_001161490.1\|35268_35829_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0
WP_000027057.1\|38234_39095_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|39277_39835_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_004152334.1\|42302_43013_-	AAA family ATPase	NA	NA	NA	NA
WP_001044770.1\|43086_43503_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_001261282.1\|43499_43730_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_072202616.1\|43686_44148_+	hypothetical protein	NA	NA	NA	NA
WP_000493378.1\|44291_44642_+	hypothetical protein	NA	NA	NA	NA
WP_000129823.1\|44692_45436_+	hypothetical protein	NA	NA	NA	NA
WP_000015958.1\|45432_46209_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	6.4e-53	92.9
WP_000764642.1\|46266_46524_-	hypothetical protein	NA	NA	NA	NA
WP_032409716.1\|46652_46757_-	hypothetical protein	NA	NA	NA	NA
WP_004118283.1\|47291_48158_+	replication initiation protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
WP_000339857.1\|48514_48784_-	hypothetical protein	NA	NA	NA	NA
WP_000368714.1\|49198_50404_+	AAA family ATPase	A0A077SL49	Escherichia_phage	2.4e-163	69.6
WP_000064120.1\|50403_51378_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	2.6e-88	54.4
WP_004118291.1\|51459_52731_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	4.9e-151	63.3
WP_000776034.1\|52730_53162_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.6e-29	53.3
WP_004178082.1\|53567_55055_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_001776122.1\|55524_56490_+	DUF1738 domain-containing protein	A0A1V0EEV1	Caulobacter_phage	1.6e-58	42.7
WP_001776120.1\|56969_57401_+	hypothetical protein	NA	NA	NA	NA
WP_001776119.1\|57433_57961_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.7e-21	39.5
WP_001166628.1\|58220_58676_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_004200999.1\|58747_59113_+	mercuric ion transporter MerT	NA	NA	NA	NA
WP_000732275.1\|59128_59404_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_000522996.1\|59431_59857_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000209296.1\|59895_61581_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_001277466.1\|61598_61964_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_001087807.1\|61960_62197_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001067855.1\|62307_63012_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_071549088.1\|63036_63549_+	restriction endonuclease	NA	NA	NA	NA
WP_001749967.1\|63553_63760_+	hypothetical protein	NA	NA	NA	NA
WP_072094655.1\|64171_65575_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	9.0e-106	50.6
WP_004098817.1\|65608_66823_-	type II site-specific deoxyribonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
WP_001389365.1\|67083_67848_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001144737.1\|67990_68257_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_004201280.1\|68477_68951_-	trimethoprim-resistant dihydrofolate reductase DfrA14	G3MBI7	Bacillus_virus	8.4e-16	28.9
WP_000845048.1\|69106_70120_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001067855.1\|70854_71559_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_032441643.1\|71598_72078_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	3.0e-77	98.1
78982:79803	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP018447

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018447_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018447_1

1153317-1153425

Orphan

Consensus_repeat	Method
TGTCCCACCCTGTACCACTTTTTTTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018447_1

>merge|NZ_CP018447|1|1153317-1153425|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTTTAAACCAAATTCTGTAATGTGGGACGCTGAAACCCGCGCCAGCTCTGCGTGTACCACTTGTCCCACCCTGTACCACCTTTTTTTA

>NZ_CP018447|1|1|1153317-1153425|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTTTAA	ACCAAATTCTGTAATGTGGGACGCTGAAACCCGCGCCAGCTCTGCGTGTACCACT
TGTCCCACCCTGTACCACCTTTTTTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018447.1\|WP_071844617.1\|1148736_1148943_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_073546842.1\|1153443_1155513_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
NZ_CP018447.1\|WP_032418448.1\|1150407_1151388_-\|PTS-glucitol/sorbitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226255
NZ_CP018447.1\|WP_032418451.1\|1151755_1152277_-\|PTS-glucitol/sorbitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226253
NZ_CP018447.1\|WP_032418445.1\|1148093_1148252_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_031591564.1\|1164510_1165143_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374550
NZ_CP018447.1\|WP_032418460.1\|1160237_1160885_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_000102105.1\|1165259_1165502_+\|Rha-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP018447.1\|WP_032418461.1\|1160886_1162134_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|170049
NZ_CP018447.1\|WP_032418453.1\|1152389_1152674_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|372675
NZ_CP018447.1\|WP_000155498.1\|1163466_1164507_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|222904
NZ_CP018447.1\|WP_032418447.1\|1149383_1150397_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP018447.1\|WP_032418449.1\|1151384_1151759_-\|PTS-glucitol/sorbitol-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226254
NZ_CP018447.1\|WP_123836165.1\|1146703_1147249_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_087757875.1\|1152768_1153125_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP018447.1\|WP_032418462.1\|1162430_1163477_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_032418459.1\|1156245_1160049_-\|DNA-binding-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_031591568.1\|1165534_1166044_+\|phage-regulatory-CII-family-protein	unknown	unknown	gnl\|CDD\|369127
NZ_CP018447.1\|WP_032418458.1\|1155548_1155764_-\|AlpA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225848
NZ_CP018447.1\|WP_032418444.1\|1147270_1147720_-\|phage-virion-morphogenesis-protein	unknown	unknown	gnl\|CDD\|368274

Protein	Function_ID	Function_description	E-value
NZ_CP018447.1\|WP_073546842.1\|1153443_1155513_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	0
NZ_CP018447.1\|WP_031591564.1\|1164510_1165143_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374550	pfam16452, Phage_CI_C, Bacteriophage CI repressor C-terminal domain. The C-terminal domain of the CI repressor functions in oligomer formation.	2.36213e-41
NZ_CP018447.1\|WP_032418451.1\|1151755_1152277_-\|PTS-glucitol/sorbitol-transporter-subunit-IIC	gnl\|CDD\|226253	COG3730, SrlA, Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism].	6.94718e-79
NZ_CP018447.1\|WP_032418449.1\|1151384_1151759_-\|PTS-glucitol/sorbitol-transporter-subunit-IIA	gnl\|CDD\|226254	COG3731, SrlB, Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism].	3.73192e-58
NZ_CP018447.1\|WP_000155498.1\|1163466_1164507_-\|site-specific-integrase	gnl\|CDD\|222904	PHA02601, int, integrase; Provisional.	0
NZ_CP018447.1\|WP_032418453.1\|1152389_1152674_-\|transcriptional-regulator	gnl\|CDD\|372675	pfam13693, HTH_35, Winged helix-turn-helix DNA-binding.	1.06433e-37
NZ_CP018447.1\|WP_032418447.1\|1149383_1150397_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.08412e-65
NZ_CP018447.1\|WP_032418461.1\|1160886_1162134_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	7.36952e-145
NZ_CP018447.1\|WP_032418448.1\|1150407_1151388_-\|PTS-glucitol/sorbitol-transporter-subunit-IIB	gnl\|CDD\|226255	COG3732, SrlE, Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism].	1.71362e-173
NZ_CP018447.1\|WP_087757875.1\|1152768_1153125_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.98259e-09
NZ_CP018447.1\|WP_031591568.1\|1165534_1166044_+\|phage-regulatory-CII-family-protein	gnl\|CDD\|369127	pfam06892, Phage_CP76, Phage regulatory protein CII (CP76). This family consists of several phage regulatory protein CII (CP76) sequences which are thought to be DNA binding proteins which are involved in the establishment of lysogeny.	4.13487e-84
NZ_CP018447.1\|WP_032418458.1\|1155548_1155764_-\|AlpA-family-transcriptional-regulator	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	5.83127e-21
NZ_CP018447.1\|WP_032418444.1\|1147270_1147720_-\|phage-virion-morphogenesis-protein	gnl\|CDD\|368274	pfam05069, Phage_tail_S, Phage virion morphogenesis family. Protein S of phage P2 is thought to be involved in tail completion and stable head joining.	6.12186e-39

>NZ_CP018447.1|WP_087757875.1|1152768_1153125_+|helix-turn-helix-transcriptional-regulator
MPEDGCCPERDNSCIFRCRVAIVIGKRLKISRVRADLTQAELGVLAGLDEESASARISSYEKEVHAPDFKLVCKLAAALDVPEAYFYAVDDELAELILQYHRFKKNNPGRTLLFSPNP
>NZ_CP018447.1|WP_032418453.1|1152389_1152674_-|transcriptional-regulator
MKKSTTKDWHPADIIAALHKRGTSLAKLSREAGLASSTLSNTLTRAWPKGEWLIAIALDVHPSEIWPGRYLNSSNKREPRKPLHPMTTTDNSGT
>NZ_CP018447.1|WP_032418451.1|1151755_1152277_-|PTS-glucitol/sorbitol-transporter-subunit-IIC
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTIRMEKVAALLGRSRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSKRGNVP
>NZ_CP018447.1|WP_032418449.1|1151384_1151759_-|PTS-glucitol/sorbitol-transporter-subunit-IIA
MMIYCARITAIGLFVADGLTDKMLITFDSNGPKDCLDYSLSLEPSFREESLMILPGDRLMLAGHDYLVTAVGKGAQQALFELGHLTLVFNGDLNPCHTGTVHLSGPVPNLRDLHGNLVIEEGRP
>NZ_CP018447.1|WP_032418448.1|1150407_1151388_-|PTS-glucitol/sorbitol-transporter-subunit-IIB
MNTVLIPPGPGGYGKGLWLPVASGKKVLSLTGREIHPVAIEIGALTESEIVNGFSDIPPDNDILCVVINCAGSLRCGLYPQKGIPTINVLPTWRAGPLAHFITEENYVSDVTMEQLVLVDTAEAPDSEPEITPEPALRVITTPPPPRGAEKLVRMVEQTGTAVGHVIALLFAASREAVDVSLRNVIPFMAFVSLLIALVQETALGSLIAHAMTPLANSLWGLVLLSLICGIPFLSPVLGPGAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGVPAFLLSRQLTGPLAVIIGWLFSLGLF
>NZ_CP018447.1|WP_032418447.1|1149383_1150397_-|Gfo/Idh/MocA-family-oxidoreductase
MNKIRAAVVGAGIYGKHHMNAYRHNPDTVLVAICDTDTERCDDLAMAYGVIGYTRLDVLLQEEAIDVVSVATPDPYHTESILTALRHGKHVLAEKPLATSVRECELIVEMAQQRDLLVGVDFHKRWDLAVMRIKAELEKPEAGRILRGHISMDDVISVPTEWLNWAGASSPVWFLGSHCFDLVRHLSGQEVVSVYAVGQKRLMVECGLDTFDSVQSLLTMADGSSWVVENSWVLPEGFPKDNDGRIDILCEATYIRSTSQHLGLEITTPGMTLTPNSYFINYRNGIASGFGIDPINDFVRAVRNRSPYPVTAVDGLAVSRICEAVHRSLKSGKPEKI
>NZ_CP018447.1|WP_071844617.1|1148736_1148943_-|hypothetical-protein
MESEHEAINIALTIENGVVTNVRQIRKDEHIASLETFLWIVKRAGYEVVPPQESTQDPENIKVLAEVE
>NZ_CP018447.1|WP_032418445.1|1148093_1148252_-|hypothetical-protein
MPGSDPTTNGDLSADIRQLVSALEGCALQVRTVKNCQDKIDVQAKESAKSLN
>NZ_CP018447.1|WP_032418444.1|1147270_1147720_-|phage-virion-morphogenesis-protein
MNDFKPFDDKLAGLIAALSPTARRKMAADIAKPLRARQQRRIKTQKAPDGTPYAARKRQPVKAKKDRVKREMFAKLRISRFMKATAGNDVAVVEFTGKVQRMVNVHQYGLKDKPSPNSGSVEYPARILLGFSPSDIDFASTKIVNYLSE
>NZ_CP018447.1|WP_123836165.1|1146703_1147249_-|hypothetical-protein
MRKLSKGNEGAIDKKIELMIKVIIRTDSYLNSANTKSTILLSLSSALLVALSVNFKNITGMVIVDSDKAVLAVLISLMIFLLITSIVFSLRGITPYIKPSTVSNTFSFVDISINFHELHLYKERFNSVSKLEYLNELISLNHNLSKALVAKYNKQITAITCIEATAYVLCFSVYMIIIANC
>NZ_CP018447.1|WP_073546842.1|1153443_1155513_-|DUF927-domain-containing-protein
MKRAPFLCKQSPDRTLEVVILAGSLAWETSRIWRKDPEREDDVPPVVLGPDELADLDNLTIIRPDTLYVRVLRTGDIREEELLKIAVKLAHAGVQMARLMSPDGELLEDWSGQLARLRQERPSDILPDHFRLDEEALWFDKLTERRDGESDVQPQRICSPLRVTAITCDSHDDSYGRLLEWHTTTGQLRRWAMPMAMLSGNGEELRRILLENGLTYISTRPALRSLLCEYISRSLPGRRVTCVEKTGWHNGVYVLPDEVIGPGGDNIILQGSHYLTGGFAQAGTLAEWQGQVAALCAGNSRLVFAVCCALAAPLLRLTGTGGGGFHLRGESTDGKTTVMKVAASVCGGTDYWHSWRATGNALEGIASRHNDALLPLDELREVDPREAGMIAYMLANGQGKGRARTDGEVRNRRHWTLLLFSTGELSLAEHTERAGERLYAGMDVRMVQIPSDTGNHGAFEQLHGFASGQQFADTLCDRVARFHGTAFRAWLAFLTHDQDASTTLARELLRRYQTALMPENAGNQVQRIVARFALLAVAGEMATLQGITGWQEGTAYGAVQICLHAWLNERGHIANQEDEGVLAQIKRFITAHQYSRFASWDGPDRPLNMVGFRRVEKDPLTGEEYTLFHILPEGWREMCRGFSPARAARLCLEAECLLPGSDGKYQSQVRLPDIGKARVYRLTSRILSI
>NZ_CP018447.1|WP_032418458.1|1155548_1155764_-|AlpA-family-transcriptional-regulator
MKTRADNNDAFPESGNVRMRQVVQFLAMSESSVYRLIKDTDFPRPVHLSSRLVVFDAAEIRQWQQRRAAIR
>NZ_CP018447.1|WP_032418459.1|1156245_1160049_-|DNA-binding-protein
MALLDKIKSLISANETATQNIEEESVYDTLTPKIITDSSVKHYFDALDFAFSKQDVKNIAITGPYGAGKSTVIQSYLKTHLNREFINVSLADFSLSGKSDEAPLENSEIELSILQQILYKENKDNLPDSRIDRIQNRNKKHISSLFLTVLSVVAPLLLLAITIFPKYFFSLFGATEPTINVIVNMFPERFFVSIIMGLLCLFFIVRVASKAGIFDKKIKLSKIAFLQGSADMASQESSSLLNNCLDEIVYFFSRSQYKIVVFEDLDRLGNAEVFVKLREINQIVNNNLQSEPVRFIYACRDDIFLGADIRTKFFDFILPVIPVMDARNAYTHLKNKLYDFPENEQPLLKQMSLYISDMRSLQNIVNEFNLFKKVVDDNTNQAKIFALIFYKNIYAQDYNLTDKKSGVLYSFIHNYRLRKLHENHFKLLDQRLEELNNKLVKIRKESVSTDAELRKQIISRFISPELWPIVYFIKDTGNYHQRYIKFSAESFYNSEHEFINYFEQNSSLYIGYPFNGNQHQLAKIDSTSIIEEYKQRNILISSNRDDAYKKTTKEIEELKENIRTRNAISLANLLKIIGWENFRTIAEEYIATCDDRTIIDPEQLETIRNGFRFGGFEALYYLLTNGYIMQDFMMFRSIFNQGTISANDNDYIKAVGRYIGCEEANQTFLLDNSKDVLAELVGQHYQYREGALHHQIIAFLLDSQDNQDHKTLSAMIAMIFRQPASVIIAIFKILEDRFINVDYFTRLVVSSLSENKYLDKMISVLKEQEHNAISKSIASKMIALVSPDISTDQKNYQKFIEDLGFSLVSEVEPNNLQYFLHNIEQLQVIYHDIYLPVTPNEMKALNFIGDHQMYPLDRATYRVVVAGLLQSDNVTCEMVDDLPWSLLDKHQLSKIKVYVNDNINIFVKDIFIDSKESSNAIVSVITHSDLSDELKILILEKMQFTVTGLNEFPEYIDVDGNELSYHDLFYRYDHVTPGWEALLAYICEECNLEILTQYIENYADVLSQEAINLMEGDRYDLLYMKVICNDNLSDSAYAAILEPVYINTHHWDERMSLKNLYRLIKNRKIELDPETFKQAIQYFISNNDLKRIEPFVLWFSQFKDNFFPNIEYYLCVNQDDVFFKESLIGINNSHVFTLQEKSSILFKCREHYELSLFEELTISNEGLIALVNTSTDDNFTIYVIIKLLKNGYRSRTEIAHFVSRLEEKEYTKIFYQKSATLNLDKPQEAELFLSALQQANLIKKWTLRDVGKYYVQCRYEEDESYLD
>NZ_CP018447.1|WP_032418460.1|1160237_1160885_-|hypothetical-protein
MTSPIRQNLFERECDMPLLEARHLALLLLGLDASQPANALPEEHQENYRILHDAISRTIKATGMVSAPANKRMFYADEMFALAWRLIDDELTPPEIKARSLKAVMKLSRNSRGRKWLKTLGDDALPDLTTSAQPSQRGMHKRDKARENTARLCWLLVQLLVEETDGRYGTSDKPASDRILRKLRALAQERELPSDGLGRGTFYEVLKMGRERKYR
>NZ_CP018447.1|WP_032418461.1|1160886_1162134_-|tyrosine-type-recombinase/integrase
MPKQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKVWHFEYYHPITKKRTKTSLGPYPVVTLAMARETRTQYRRLLYQGIDPRQHLAGIAEEKRIQTECTLEKVAGQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGSTPVTEIRPKMLKEHLTPLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLTLQNASIRKETRCLIEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQQTANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLESALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQALLGEEEPLRIVEGE
>NZ_CP018447.1|WP_032418462.1|1162430_1163477_-|hypothetical-protein
MLVNNYIQQYPWISYLLIIIYFIYICLELYLCVSKKGFNMDERPLTSQYLFKQSLRIPVFSAIYFGIFSWLGHSPQFDSEGFNNFIAISKLPIALLSLSIPFVAVVANIHRTVQTNRQIEETKQKNLSDSYYSHLKFVTDYFTNLPNKTIKRERHYGTKEISYKINYPIHLYRYIFINSSPEKGRPKNTDKEYIREVNNHWVDILKNLEKIHSSNRGSQFDEVLIRQMQSLHSIEKHLSELNRMLCLTPMELNEHATLYFDGYEMITNFMSSIELGDTIETYFKFTIDILDITDNFLSFKDDGSSGQIIILARLLKNNNPAIFDEIVTNKGKAQPSLTYNGDRLATEH
>NZ_CP018447.1|WP_000155498.1|1163466_1164507_-|site-specific-integrase
MTIRKQPNGKWLCECYPNGRNGKRVRKQFATKGEAIAFESFTMEEVNKKPWLGEKEDRRHLSELIELWYSLYGQTLADPKRLMAKLRIICNGLGDPIASELTAGEFTKYREARLKGEVRNEDGTLMSPVKPRTVNLEQRNLSSVFGTLKKLGHWSAPNPLAGLPTFKIAEGELAFLTPEEIKRLLDACADSQSPSLLMIAKICLATGARWSEAENLQSHQVSKYRITYTKTKGKKNRTVPISKDLYEELPKNRGKLFTPCRKAFERAVKRAGIELPEGQCTHVLRHTFASHFMMNGGNILVLRDILGHVDIKMTMIYAHFAPDHLEDAVTKNPLANLGWRKLESAC
>NZ_CP018447.1|WP_031591564.1|1164510_1165143_-|helix-turn-helix-domain-containing-protein
MSLIKAGNDSGGRDAINRLIKAYNFSSRQQLCEHLEVSKSTMANRYLRDSFPAEWVIQCALETGASLLWLATGQGDMYACENEETNLKSEPPVTVRTLSKIVAPSIKRVELKNGELQPSDEILLDSSLLDGDSSNALFVKTANDSFVVDTSVKQVSNGFWLVDMDGVKSIVKIARIPGNKIVVNQDDTSFECSVDDVEVVGRAVKVIKNL
>NZ_CP018447.1|WP_000102105.1|1165259_1165502_+|Rha-family-transcriptional-regulator
MSTDISIRVPKEMATPAEFAEWEGISRGSVYQKIHHGQLAKYMVKKEKNKGRVSLRYLMYKTDQVRESLGHSNFRVIVGK
>NZ_CP018447.1|WP_031591568.1|1165534_1166044_+|phage-regulatory-CII-family-protein
MFDYKISKHPHFDEACRAFALRHNMAKLAERAGMNVQTLRNKLNPDQPHQLNAPEIWLLTDLTEDSTLIDGFLAQIHCLPCVPINEVAKEKLPHYVMSATAEIGRVAAGAVSGDVKTSAGRRDAISSINSVTRLMALAAVSLQARLQANPAMASAVDTMTGLGASFGLL

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Crispr_ID: NZ_CP018447_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018447_2

1770052-1770314

Orphan

Consensus_repeat	Method
AGCGCCATCAGGCAGTGTGGCGGCTACGCCTGACCCGGCCTGGATTATACGGTGGGTGTGA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP018447_2

>merge|NZ_CP018447|2|1770052-1770314|PILER-CR
AGCGCCATCAGGCAGTGTGGCGGCTACGCCTGACCCGGCCTGGATTATACGGTGGGTGTGATACCCCGATTAGTTCGCCATCCCGTAGGCCTGATAAGCGAAGCGCCATCAGGCAGTGTGGCGGCTGCGTCTGACCCGGCCTGGATTATACGGTGGGTGTGATACCCCGATTAGTTCGCCATCCCGTAGGCCTGATAAGCGAAGCGCCATCAGGCAGTGTGGCGGCTACGCCTGACCCGGCCTGGATTATACGGTGGGTGTCA

>NZ_CP018447|2|1|1770052-1770314|PILER-CR
AGCGCCATCAGGCAGTGTGGCGGCTACGCCTGACCCGGCCTGGATTATACGGTGGGTGTGA	TACCCCGATTAGTTCGCCATCCCGTAGGCCTGATAAGCGA
AGCGCCATCAGGCAGTGTGGCGGCTGCGTCTGACCCGGCCTGGATTATACGGTGGGTGTGA	TACCCCGATTAGTTCGCCATCCCGTAGGCCTGATAAGCGA
AGCGCCATCAGGCAGTGTGGCGGCTACGCCTGACCCGGCCTGGATTATACGGTGGGTGTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018447.1\|WP_032418658.1\|1758736_1760011_+\|dicarboxylate/amino-acid:cation-symporter	unknown	unknown	gnl\|CDD\|224220
NZ_CP018447.1\|WP_020324291.1\|1775343_1775466_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_162900877.1\|1778467_1778911_+\|protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|182256
NZ_CP018447.1\|WP_032418662.1\|1774167_1774797_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|214471
NZ_CP018447.1\|WP_001741945.1\|1772884_1773775_+\|GalU-regulator-GalF	unknown	unknown	gnl\|CDD\|182252
NZ_CP018447.1\|WP_004151143.1\|1764251_1765604_-\|molecular-chaperone	unknown	unknown	gnl\|CDD\|236954
NZ_CP018447.1\|WP_009483956.1\|1760284_1760896_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|197715
NZ_CP018447.1\|WP_032418661.1\|1768048_1769896_+\|outer-membrane-assembly-protein-AsmA	unknown	unknown	gnl\|CDD\|236772
NZ_CP018447.1\|WP_032419447.1\|1762105_1763962_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP018447.1\|WP_004151141.1\|1761389_1762091_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP018447.1\|WP_004151147.1\|1770535_1772119_-\|TerC-family-protein	unknown	unknown	gnl\|CDD\|223930
NZ_CP018447.1\|WP_032418664.1\|1775756_1777190_+\|capsule-assembly-Wzi-family-protein	unknown	unknown	gnl\|CDD\|379441
NZ_CP018447.1\|WP_004146563.1\|1761011_1761152_-\|small-membrane-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_002912442.1\|1766704_1767346_+\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492
NZ_CP018447.1\|WP_077261140.1\|1782625_1783693_+\|glycoside-hydrolase-family-99-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|211420
NZ_CP018447.1\|WP_032418660.1\|1765741_1766590_+\|DNA-3-methyladenine-glycosylase-2	unknown	unknown	gnl\|CDD\|236671
NZ_CP018447.1\|WP_004151145.1\|1767436_1768018_+\|dCTP-deaminase	unknown	unknown	gnl\|CDD\|274062
NZ_CP018447.1\|WP_032418666.1\|1777334_1778468_+\|polysaccharide-export-protein	unknown	unknown	gnl\|CDD\|237903
NZ_CP018447.1\|WP_102097631.1\|1781582_1782590_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_073546854.1\|1778925_1781094_+\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|183173

Protein	Function_ID	Function_description	E-value
NZ_CP018447.1\|WP_032418658.1\|1758736_1760011_+\|dicarboxylate/amino-acid:cation-symporter	gnl\|CDD\|224220	COG1301, GltP, Na+/H+-dicarboxylate symporters [Energy production and conversion].	5.58793e-108
NZ_CP018447.1\|WP_162900877.1\|1778467_1778911_+\|protein-tyrosine-phosphatase	gnl\|CDD\|182256	PRK10126, PRK10126, low molecular weight protein-tyrosine-phosphatase Wzb.	2.45736e-66
NZ_CP018447.1\|WP_032418662.1\|1774167_1774797_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|214471	smart00014, acidPPc, Acid phosphatase homologues.	9.62171e-17
NZ_CP018447.1\|WP_004151145.1\|1767436_1768018_+\|dCTP-deaminase	gnl\|CDD\|274062	TIGR02274, Probable_deoxycytidine_triphosphate_deaminase, deoxycytidine triphosphate deaminase. Members of this family include the Escherichia coli monofunctional deoxycytidine triphosphate deaminase (dCTP deaminase) and a Methanocaldococcus jannaschii bifunctional dCTP deaminase (3.5.4.13)/dUTP diphosphatase (EC 3.6.1.23), which has the EC number 3.5.4.30 for the overall operation. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	1.60713e-93
NZ_CP018447.1\|WP_004151143.1\|1764251_1765604_-\|molecular-chaperone	gnl\|CDD\|236954	PRK11678, PRK11678, putative chaperone; Provisional.	0
NZ_CP018447.1\|WP_073546854.1\|1778925_1781094_+\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|183173	PRK11519, PRK11519, tyrosine-protein kinase Wzc.	0
NZ_CP018447.1\|WP_032418661.1\|1768048_1769896_+\|outer-membrane-assembly-protein-AsmA	gnl\|CDD\|236772	PRK10833, PRK10833, putative assembly protein; Provisional.	0
NZ_CP018447.1\|WP_032419447.1\|1762105_1763962_-\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.38058e-41
NZ_CP018447.1\|WP_004151141.1\|1761389_1762091_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.98041e-36
NZ_CP018447.1\|WP_004151147.1\|1770535_1772119_-\|TerC-family-protein	gnl\|CDD\|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	9.01248e-99
NZ_CP018447.1\|WP_032418664.1\|1775756_1777190_+\|capsule-assembly-Wzi-family-protein	gnl\|CDD\|379441	pfam14052, Caps_assemb_Wzi, Capsule assembly protein Wzi. Many bacteria are covered in a layer of surface-associated polysaccharide called the capsule. These capsules can be divided into four groups depending upon the organisation of genes responsible for capsule assembly, the assembly pathway and regulation. This family plays a role in group 1 capsule biosynthesis. It is likely to be involved in the later stages of capsule assembly. It is likely to consist of a beta-barrel structure.	1.13171e-133
NZ_CP018447.1\|WP_009483956.1\|1760284_1760896_-\|response-regulator-transcription-factor	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	0.00203687
NZ_CP018447.1\|WP_002912442.1\|1766704_1767346_+\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	1.7406e-147
NZ_CP018447.1\|WP_077261140.1\|1782625_1783693_+\|glycoside-hydrolase-family-99-like-domain-containing-protein	gnl\|CDD\|211420	cd11579, Glyco_tran_WbsX, Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases. Members of this domain family are found in proteins within O-antigen biosynthesis clusters in Gram negative bacteria, where they may function as glycosyl hydrolases and typically co-occur with glycosyltransferase domains. They bear resemblance to GH71 and the GH99 family of alpha-1,2-mannosidases and may share a similar cataltyic site and mechanism. The O-antigens are essential lipopolysaccharides in gram-negative bacteria's outer membrane and have been linked to pathogenicity.	4.85027e-35
NZ_CP018447.1\|WP_032418660.1\|1765741_1766590_+\|DNA-3-methyladenine-glycosylase-2	gnl\|CDD\|236671	PRK10308, PRK10308, 3-methyl-adenine DNA glycosylase II; Provisional.	1.93566e-179
NZ_CP018447.1\|WP_001741945.1\|1772884_1773775_+\|GalU-regulator-GalF	gnl\|CDD\|182252	PRK10122, PRK10122, UTP--glucose-1-phosphate uridylyltransferase GalF.	0
NZ_CP018447.1\|WP_032418666.1\|1777334_1778468_+\|polysaccharide-export-protein	gnl\|CDD\|237903	PRK15078, PRK15078, polysaccharide export protein Wza; Provisional.	0

>NZ_CP018447.1|WP_032418661.1|1768048_1769896_+|outer-membrane-assembly-protein-AsmA
MRRILTTLMILLAVIVAGLTSLVLLVNPNDFRAYMVHEVAERSGYQLDLDGPLRWHVWPQLSILSGRMTLTARGAEEPVIRADNMRLDVALLPLLSHQLQVKQVMLKGAVIQLTPKTEAVRDSSAPVVPHDNTLPLAPEDRGWSYDVRQLQVADSVLFFQHENGEQVTVRDIRLQMEQDENHRATVDFSGRVNRDQRDLALNFSATVQGGDYPHSLKADFTQLSWQLRGAELPPDGINGQGSLQASWQEDDKTLRFDNLNLMANRSTVTGSGSVVLGDRPDWSLDLHATTLDLDSLLAQRSPATDSSASQQGQSQTRPLRPVIADSDEREDYQSLRGFNGRMALSADQLQWRGLNFTQVQSEISNQQGLLTVSKMQGNLDGGQLSLPGTLDARGDTPLATFQPALQNVEIGSLIKAFNYSLNLTGKLSLSGEFSGTRIDADDFRRHWQGQAQLQMADTRTEGLNFQQLVQQAVERSTNVRAQDNYDNATRLDSVSSRLTLDNGLVTLNRLQGQSDVMAMTGEGQLDLQKENCDMRFNVRVLGGWKGEGKLIDRLKQTAIPLRIYGEWQSLSYSLQVDQILRKQLQDEAKQRLNDWVERNKGSKDGNDAKKLLDKL
>NZ_CP018447.1|WP_004151145.1|1767436_1768018_+|dCTP-deaminase
MRLCDRDIEAWLDEGRLAINPRPPVERINGATVDVRLGNKFRTFRGHTAPFIDLSGPKAEVSAALDRVMSEEIVLPEGEAFFLHPGELALAVTYESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMPIGALSFEPLSGPAARPYNRREDAKYRDQQGAVASRIDKD
>NZ_CP018447.1|WP_002912442.1|1766704_1767346_+|uridine-kinase
MTDMSHQCVIVGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPSSMDHSLLFQHLQMLKSGQPIELPVYSYVEHTRTPNTIHVEPKKVIILEGILLLTDARLRNELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
>NZ_CP018447.1|WP_032418660.1|1765741_1766590_+|DNA-3-methyladenine-glycosylase-2
MVLLPWTPPYDWAWMVGFLQARAVAGVERFHDGGYSRSFGVEGHRGLIHLAPDEEAQGLRVTLSPGLQPVAEICYARIGQLFDLACDPRQVARTLGDLPQARPGLRLPGALDAFEQAVRAVLGQLVSVAMAARLTAKVAAGWGEPLAEAPGYVLFPTPEALSRADPQALKALGMPLRRAEALIHLARAALNGELPLTAPADIDAGLRQLQTLPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAAIARYARRWQPMRSYALLHIWYTDDWAPAAE
>NZ_CP018447.1|WP_004151143.1|1764251_1765604_-|molecular-chaperone
MFIGFDYGTANCSVAVMRENTPQLLTLENGSALLPSMLCAPTREAVSEWLYRHHDVPTHSDENQALLRRAIAANRDEDIEVLRNSVQFGLASLQQYVEDPEEVYFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIKLQAESQLPEQIDQAVIGRPINFQGLGGDEANAQAQGILERAAHRAGFRDVVFQFEPVAAGLDFEATLSEEKRVLVVDIGGGTTDCSLLLMGPQWRERADRQQSLLGHSGCRIGGNDLDIALAFKCLMPLLGMGGETEKGTALPILPWWNAVAINDVPAQSDFYSTANGRLLNDLLRSARDADKVALLLKVWRQRLSYRLVRSAEESKIALSSAASVETALPFIQDDLATAIAQQGLEAALDQPLTRIMEQVRLALDSSQTTPDVIYLTGGSARSPLIKKALAAQLPGIPLAGGDDFGSVTAGLARWAQVVFR
>NZ_CP018447.1|WP_032419447.1|1762105_1763962_-|sensor-histidine-kinase
MLLVAPQAQAATRQVGIDIPVQWYADASGQMTLDRFAALPTDQLATTRQIPSFGYSRKTWWLRSELPGTWFAGEPRWLQLGPSFVDHLTIYYRPLGSDAPWAQRTFGDRDGARESDLHYRESVLILPPPPTAAGYEVVFRLQSTSTLILLASLSSPQEFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAALHGFPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVLQVSIPLGFYGFAMQIEGVVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVVAAVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRAENRQLEQKQRLARELQIEREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLTDNCLADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLCIAIANLLDNAVKYSPPGEIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTLPTVA
>NZ_CP018447.1|WP_004151141.1|1761389_1762091_-|response-regulator-transcription-factor
MALRLAIIEDNADLLDELLAWLGYRGFEVWGTRSAEAFWRQLHSHPVDIVLVDIGLPGEDGFSVLNYLHELGHYGLVVVSARGQQQDKLQALSLGADAYLIKPVNFAHLAETLTALGARLRQDRPAAPPAEAIGTPPAVSPGSWRLQEDKLISPDARTLELTQQEYRLVELLMRNRNEVCSKLDLHACLFSHESEPDLHRIDVVVSRLRHKARQQGIHLPVRAIFGKGLAFIS
>NZ_CP018447.1|WP_004146563.1|1761011_1761152_-|small-membrane-protein
MAMQTWLVLLLCIFFFSISVYSFISYLKDRRRQKFTFNDKRSMRRK
>NZ_CP018447.1|WP_009483956.1|1760284_1760896_-|response-regulator-transcription-factor
MRNINVTINTRNAFVRESLVAMVNDLTRGDLRARFSWRNTDLSAEDIIICEVIPGEIYLCNTLIKNRKRGSSLIILHSYDQLPEDEFMINCLKGVIFVSLKTASIPQLLTIIKSELQHCMTPTATDAAGRELSCASCPHRVLSRSQTAVVHGILEGLDMSKIAALQRVSPRTAAYHKNKIMEKYSLNNNHEFFQFMNLLRERW
>NZ_CP018447.1|WP_032418658.1|1758736_1760011_+|dicarboxylate/amino-acid:cation-symporter
MANANKLTLFIVIFMLMGILSGAAIHAYATPTTISAWADNITLLTDLFLRLIKMVIAPLVFSTLTVGIMRLGETATIGRVGGKAMVWFITSSVLSILVGLVIVTFQHPGAGLNLAVPKEAVDTGLAVSGMSLKGFLSHTIPTSITEAMANNEILQIVVFSMFFGIAGASLGEKFNAPLVAALNVVSHIMLKVTGYVMYVAPLAIFAAISSVIASQGLGILLNYASFIGGYYLAVLLTSSVLIAVGYMVLKKEVFRLLNMLKDPVLVAFTTSSSEAAYPKTLERLVKFGCSRNIVSFVLPIGYSFNLVGSMVYCSFAAMFIAQAYNVPLSFSEITVMMLTLMLASKGIAGVPRSALVVLAATIPSFNIPVAGILLLMGIDHFLDMGRSAINVLGNGIATAMLSKNEGLLTDEEAQPDWEVEKAEA
>NZ_CP018447.1|WP_004151147.1|1770535_1772119_-|TerC-family-protein
MEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDRARITGLMLAMVMRLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAAIGFSVMIEALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNPQERLMIERVLNLNQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLLSALEQFRQARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDLVQYVPLPLDDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDYEV
>NZ_CP018447.1|WP_001741945.1|1772884_1773775_+|GalU-regulator-GalF
MANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNETGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRNLKEGAKFRESIKKLLA
>NZ_CP018447.1|WP_032418662.1|1774167_1774797_+|phosphatase-PAP2-family-protein
MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWGLLFGITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSVGLRKAAVITGYVLAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLVLQKRTSDPESVNISWGGVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQVW
>NZ_CP018447.1|WP_020324291.1|1775343_1775466_-|hypothetical-protein
MMIILTGSIFTAVEENLCAAASGFSDATAPGLTATSALTT
>NZ_CP018447.1|WP_032418664.1|1775756_1777190_+|capsule-assembly-Wzi-family-protein
MIKIARIAATLGLLSSLGAQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEISRALKKAKPSYSSEQVVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDVHLQGNVEGDERISNGSRFNANGAYGAVKFWNQWLSFGQMPEWWGPGYEGSLIRGDAMRPMTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHAKIIGGRFTFSPFQSLELGASRIMQWGGEGRPQSFSSFWDGFTGKDNTGTDNEPGNQLAGFDFKFKLEPTLGWPVSFYGQMIGEDESGYLPSANMFLGGVEGHHGWGKDAVNWYVEAHDTRSNMSRTDYIYTHHIYKDGYYQQGYPLGDAMGGDGQLIAGKVELITEDNQRWSTRIVYAKVNPENQSINKAFPHADTLKGVQLGWSGDVYQSVRLNTSLWYTNADNSDRDDVGASAGIEIPFSL
>NZ_CP018447.1|WP_032418666.1|1777334_1778468_+|polysaccharide-export-protein
MKKKIVRFSALALAIGFLSGCTIIPGQGLNSLRKNVVELPDSDYDLDKLVNVYPMTPGLIDQLRPETVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPELTTPAGQYRSASDTGNWVNSDGTIFYPYIGKLQVAGKTISQVRQDIASRLTTYIESPQVDVSIAAFRSQKTYVTGEVVKSGQQPITNIPLTVMDAINNAGGLAPDADWRNVVLTHNGKDTKISLYALMQKGDLSQNHLLYPGDILFVPRNDDLKVFVMGEVVKQATMKMDRSGMTLAEALGNAEGISQEMSDATGVFVIRQLKDDKQGKIANIYQLNAQDASAMVLGTEFQLQPYDIVYVTTAPLVRWNRVISQLVPTITGVHDMTETGKFIRTW
>NZ_CP018447.1|WP_162900877.1|1778467_1778911_+|protein-tyrosine-phosphatase
MAMLNSILVVCTGNICRSPIAERFLRQGLPNMKIDSAGTGALIGHEADESAVKIAAFHGLSLDGHKGQQFTSSLGRHYDLILVMEKKHLEQISQISPEARGKTMLFGHWLGSRDIPDPYHKSEEAFSSVYQLIEQSGLRWIEKIGAK
>NZ_CP018447.1|WP_073546854.1|1778925_1781094_+|polysaccharide-biosynthesis-tyrosine-autokinase
MSSVNNKLITNDADEIDLGRLLGELVDHRKLIIAVTSLFTLCALIYALFATPIYQADALIQVEQKQANAIFSNLSKMLPDSQPQSEPEIALLKSRMILGKTVDDLNLQAVIKPKYFPIFGRGWQRLSGKKDGELVVSRLYLPTSEDIDVPKVELTVKDNEHFVVKGDDFTFNGKVGELLDDKGISIKVDKIDAEPGSKFTISYITRLEAITKLQEVLSVADQGKDTGILVLSITGDNPELITNIIDSISNNYLSQNIARQAAQDAKSLEFLSNQLPKVRNDLDVAEDKLNEYRRKNDSVDLSLEAKSVLEQIVNVDNQLNDLTFRESEISQLYTKEHPNYKALMEKRKTLQEEKAKLNKRVSVMPETQQEILRLSRDVESGRAVYMQLLNRQQELNIAKSSAIGNVRIIDNAVAQTKPVKPKKIVIILIGFIFGSVVAIGIVLLRVFLRRGIESPEQLEELGINVYASIPVSEAFANNAVKKASWKNKNYDIKQAFLAVENPADLAIEAIRGLRTSLHFAMMESRNNILMISGASPNAGKTFVSTNLAAVIAQSGKKVLFIDTDMRKGYTHNLFNVENTKGLSDILSGKMTVERAIQPLSMAGFDFIARGAVPPNPAELLMHKNFDALLSWASQNYEIVVLDTPPILAVTDAAIIGNYVGTTLLVARFEQNTAKEIEVSVRRFEQSGVIVKGCILNGIIKKASSYYSYGYNHYGYTYTDNKK
>NZ_CP018447.1|WP_102097631.1|1781582_1782590_+|hypothetical-protein
MAKDNSISRIILDWRDTVAPVLIMYLMVRTNVINFDDGDRILHFIALMVVGNSIIAIIDYYNFNGIAESSWRYDFLIDLNLKTDSDYESRMVVYQIVRNGNLRSSGLFVSALQYSYIAGMFCFYFYLKLLNSLKWLNFSGLALSLISMIICLAGVYVSQVRTAFLIIIFNILFYHLCLSYKNNFSFKPKLTMSLAVICSVVMFYAIYYLGESADASSYGRLAQYAIMISDFNPLGAGLGAYKGLFDSFYVYIILTLGAPSIYFIYFFVKRYIYIFSRKNIEIDKKYIPFVGVCFTAFPVMMLAMSFQHVAGSIYYTLNFLTFFISMRYLTNVSVK
>NZ_CP018447.1|WP_077261140.1|1782625_1783693_+|glycoside-hydrolase-family-99-like-domain-containing-protein
MIRLFLSQPRVFFIFIFFLISQAKAGSLDVGVYYYPGWNKPGVEVWEPIKKYPEREPILGWYQDGDDNIIQKQLAWMEKYGVTYIAYDWYWDENTGVKNRTFAIDAYLRNSQATNVKFALLWANHTNTPKNSKEFDNIVNYWIDNYFKSSKYFTINRRPVVFVFSPQRLEMDGHKFNMDVPSLLKRARLLGNKKGLKDIYFVASTGYDENNNLIYKYPPNSYDAVSAYNYHIGISNGIPKKNSYSYQELIAGYKYTWNKILSDSDLPYIIPVSSGWDRRPWGGSIPPEHDMSYGNPKEFGNMLSEAKEEIKLHQDKALNNIIICCWNEYGEGSYIEPSKKYGFKFLDEIQKNKNF

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Crispr_ID: NZ_CP018447_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018447_3

2236155-2236256

Orphan

Consensus_repeat	Method
TGTAGCCTCGCTAAGCGAAGCGCGAGCGATGAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018447_3

>merge|NZ_CP018447|3|2236155-2236256|CRISPRCasFinder
TGTAGCCTCGCTAAGCGAAGCGCGAGCGATGAGACAGCAGAACAGGTGGCTGAGAGAGTGCAGGAATGTGTAGCCTCGCTAAGCGAAGCGCGAGCGAGGAGA

>NZ_CP018447|3|2|2236155-2236256|CRISPRCasFinder
TGTAGCCTCGCTAAGCGAAGCGCGAGCGATGAGA	CAGCAGAACAGGTGGCTGAGAGAGTGCAGGAATG
TGTAGCCTCGCTAAGCGAAGCGCGAGCGAGGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018447.1\|WP_002910103.1\|2241863_2242271_-\|DNA-binding-transcriptional-regulator-H-NS	unknown	unknown	gnl\|CDD\|182858
NZ_CP018447.1\|WP_002910105.1\|2240839_2241742_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|184021
NZ_CP018447.1\|WP_002910107.1\|2239628_2240642_+\|two-component-system-response-regulator-RssB	unknown	unknown	gnl\|CDD\|182652
NZ_CP018447.1\|WP_004175566.1\|2224113_2225892_-\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX	unknown	unknown	gnl\|CDD\|182581
NZ_CP018447.1\|WP_032103886.1\|2246350_2246536_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_002910100.1\|2242832_2243450_+\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
NZ_CP018447.1\|WP_002910189.1\|2233979_2234657_+\|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl\|CDD\|273030
NZ_CP018447.1\|WP_014907381.1\|2227717_2227831_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_002910193.1\|2231737_2233273_+\|nitrate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|224063
NZ_CP018447.1\|WP_004189450.1\|2234653_2235550_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP018447.1\|WP_004152249.1\|2235657_2236101_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP018447.1\|WP_004175568.1\|2226203_2227592_+\|NarK-family-nitrate/nitrite-MFS-transporter	unknown	unknown	gnl\|CDD\|184994
NZ_CP018447.1\|WP_004145401.1\|2242693_2242825_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_002910191.1\|2233269_2233980_+\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl\|CDD\|185014
NZ_CP018447.1\|WP_002910108.1\|2238636_2239539_+\|patatin-like-phospholipase-RssA	unknown	unknown	gnl\|CDD\|182352
NZ_CP018447.1\|WP_032418823.1\|2227997_2231741_+\|nitrate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|227346
NZ_CP018447.1\|WP_002910097.1\|2243597_2246273_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
NZ_CP018447.1\|WP_002910198.1\|2223452_2224103_-\|two-component-system-response-regulator-NarL	unknown	unknown	gnl\|CDD\|182619
NZ_CP018447.1\|WP_004151854.1\|2237180_2238023_-\|formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
NZ_CP018447.1\|WP_002910109.1\|2238065_2238524_-\|YchJ-family-protein	unknown	unknown	gnl\|CDD\|234966

Protein	Function_ID	Function_description	E-value
NZ_CP018447.1\|WP_002910103.1\|2241863_2242271_-\|DNA-binding-transcriptional-regulator-H-NS	gnl\|CDD\|182858	PRK10947, PRK10947, DNA-binding transcriptional regulator H-NS.	2.61324e-79
NZ_CP018447.1\|WP_002910105.1\|2240839_2241742_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|184021	PRK13389, PRK13389, UTP--glucose-1-phosphate uridylyltransferase GalU.	0
NZ_CP018447.1\|WP_002910107.1\|2239628_2240642_+\|two-component-system-response-regulator-RssB	gnl\|CDD\|182652	PRK10693, PRK10693, two-component system response regulator RssB.	0
NZ_CP018447.1\|WP_004175566.1\|2224113_2225892_-\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX	gnl\|CDD\|182581	PRK10600, PRK10600, nitrate/nitrite two-component system sensor histidine kinase NarX.	0
NZ_CP018447.1\|WP_002910100.1\|2242832_2243450_+\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	1.66434e-117
NZ_CP018447.1\|WP_002910189.1\|2233979_2234657_+\|respiratory-nitrate-reductase-subunit-gamma	gnl\|CDD\|273030	TIGR00351, Respiratory_nitrate_reductase_2_gamma_chain., respiratory nitrate reductase, gamma subunit. Involved in anerobic respiration the gene product catalyzes the reaction (reduced acceptor + NO3- = Acceptor + nitrite). Another possible role_id for this gene product is in nitrogen fixation (Role_id:160). [Energy metabolism, Anaerobic].	2.8765e-130
NZ_CP018447.1\|WP_002910193.1\|2231737_2233273_+\|nitrate-reductase-subunit-beta	gnl\|CDD\|224063	COG1140, NarY, Nitrate reductase beta subunit [Energy production and conversion].	0
NZ_CP018447.1\|WP_004189450.1\|2234653_2235550_-\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	3.2204e-15
NZ_CP018447.1\|WP_004152249.1\|2235657_2236101_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.05574e-32
NZ_CP018447.1\|WP_004175568.1\|2226203_2227592_+\|NarK-family-nitrate/nitrite-MFS-transporter	gnl\|CDD\|184994	PRK15034, PRK15034, nitrate/nitrite transport protein NarU; Provisional.	0
NZ_CP018447.1\|WP_002910191.1\|2233269_2233980_+\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl\|CDD\|185014	PRK15054, PRK15054, nitrate reductase molybdenum cofactor assembly chaperone.	1.14838e-83
NZ_CP018447.1\|WP_002910108.1\|2238636_2239539_+\|patatin-like-phospholipase-RssA	gnl\|CDD\|182352	PRK10279, PRK10279, patatin-like phospholipase RssA.	0
NZ_CP018447.1\|WP_032418823.1\|2227997_2231741_+\|nitrate-reductase-subunit-alpha	gnl\|CDD\|227346	COG5013, NarG, Nitrate reductase alpha subunit [Energy production and conversion].	0
NZ_CP018447.1\|WP_002910097.1\|2243597_2246273_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
NZ_CP018447.1\|WP_002910198.1\|2223452_2224103_-\|two-component-system-response-regulator-NarL	gnl\|CDD\|182619	PRK10651, PRK10651, transcriptional regulator NarL; Provisional.	1.26442e-140
NZ_CP018447.1\|WP_004151854.1\|2237180_2238023_-\|formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	4.09997e-176
NZ_CP018447.1\|WP_002910109.1\|2238065_2238524_-\|YchJ-family-protein	gnl\|CDD\|234966	PRK01617, PRK01617, hypothetical protein; Provisional.	7.51559e-107

>NZ_CP018447.1|WP_004152249.1|2235657_2236101_+|Lrp/AsnC-family-transcriptional-regulator
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNLAALGYSLQALVRVRPLPGLLQKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTLLDGLAEYAQCNTSVVKSSPVKRRLPPL
>NZ_CP018447.1|WP_004189450.1|2234653_2235550_-|DMT-family-transporter
MQLTRGVWQMSLAMIISGSIGAFVLLSGLPVTDVVFWRCLIGALTLLVFIVLSRQPFSRLTRFTLALAVIGGAALVVNWLLLFAAYSRISIGMATVVYNTQPFMLVLMGMVLGERVSAVKWGWLLLAFGGVVILLSSELMPAHEEGLTTGVLLALGAAFFYALTAIIARKLHPLPAQHIAFIQVLVGVVMLLPLVHAPELTASFPWRYLLILGIVHTGIMYQLLYSAIQKLPTPVTGSLSFIYPLVAMVVDYLVFHHALSAVQLLGGMLILFAAAGNNLGWGEKKPRRGGVSEQSRAS
>NZ_CP018447.1|WP_002910189.1|2233979_2234657_+|respiratory-nitrate-reductase-subunit-gamma
MHFLNMFFFDIYPYIAGSVFLIGSWLRYDYGQYTWRAASSQMLDRKGMNLASNLFHIGILGIFAGHFLGMLTPHWMYESFLPIDVKQKMAMIAGGACGVMTLVGGLLLLKRRLLSPRVRATTTGADILILSLLMVQCALGLLTIPFSAQHMDGSEMMKLVGWAQSVVTFHGGASQHLDGVAFIFRVHLVLGMTLFLLFPFSRLVHIWSAPVEYLTRKYQIVRARR
>NZ_CP018447.1|WP_002910191.1|2233269_2233980_+|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MIELVIVSRLLEYPDAALWQHQQEMFEALASSEKLSKEDAHALGVFLRDLVAQDPLDAQAAYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLMAQYERHGLLLDSHELPDHLPLYLEYLAQLPEEEALGGLRDVAPILGLLSARLQQRESRYAVLFELLLKLANTQVDSQKVAEKIADEARDDTPQALDAVWEEEQVKFFADQGCGESEISAHQRRFAGAVAPQYLNISNGGQQ
>NZ_CP018447.1|WP_002910193.1|2231737_2233273_+|nitrate-reductase-subunit-beta
MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGMEYAWFNNVESKPGVGFPNDWENQEKWKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYEPFDYDYQNLHNAPESKHQPIARPRSLITGQRMDKITSGPNWEEILGGEFEKRAKDQNFDNMQKAMYGQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRGWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIESGMPTVCSETCVGRIRYLGVLLYDADAIENAASTENEKDLYQRQLDVFLDPNDPKVIEQALKDGVPQGVIEAAQQSPVYKMAMDWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLANLLTAGDTQPVLLALKRMLAMRHYKRAETVDGVVDTRALEEVGLSEAQAQEMYRYLAIANYEDRFVVPSSHREQAREAFPEKNGCGFSFGDGCHGSDSQFNLFNSRRIDAIDVTSKTEPHA
>NZ_CP018447.1|WP_032418823.1|2227997_2231741_+|nitrate-reductase-subunit-alpha
MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPLMRKRLMKMWREAKVQHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTVKTYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAITPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDKPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRTLRASDLVDSLGQENNPEWKTVAFDEKGDMTVPNGSLGFRWGDKGKWNLEQRDGKTGEEIELRLSLLGSHDEVANVGFPYFGGEGSEHFNKVDLENILLHKLPAKRLQLADGSTALVTTVYDLTMANYGLERGLNDDNCAAGYDEVKAYTPAWAEKITGVSRAHIIRTAREFADNADKTHGRSMIIVGAGLNHWFHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAQELLSPMADKSRYSGHLIDFNVRAERMGWLPSAPQLGVNPLRIADEAKKAGMTPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEYMLKYLLGTENGIQGKDLGKQGGVKPEEVEWRDNGLDGKLDLVVTLDFRLSSTCLYSDIVLPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWESKSDWEIYKGIAKKFSEVCMGHLGKETDVVTLPIQHDSAAEMAQPLDVKDWKKGECDLIPGKTAPHIIPVERDYPATYERFTSIGPLLETIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPKLETAIDAAEMILTLAPETNGQVAVKAWQALSEITGREHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLTGRQSLYQDHQWMRDFGESLLVYRPPIDTRSVKAVMGEKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLSRGGPIVWMSEADAKDLGIEDNDWIEVFNANGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITGQRGGIHNSVTRITPKPTHMIGGYGHLAYGFNYYGTVGSNRDEFVVVRKMKNINWLDGEGNDQVQESVK
>NZ_CP018447.1|WP_014907381.1|2227717_2227831_+|hypothetical-protein
MGLPVKWLYPLIPPLLTNPGEAPLFEVKIIKKQQVKK
>NZ_CP018447.1|WP_004175568.1|2226203_2227592_+|NarK-family-nitrate/nitrite-MFS-transporter
MSQSSLPEKANRSVITDWRPEDPEFWQQRGHRVASRNLWISVPCLLLAFCVWMLFSAVAVNLNKVGFQFTTDQLFMLTALPALSGALLRVPYAFMVPLFGGRRWTAFSTGIMIVPCVWLGFAVQDTSTPFSIFVIISLLCGFAGANFASSMANISFFFPKAKQGGALGVNGGLGNMGVSVMQLVAPLVVSISIFAVFGGNGSEQPDGSMLYLENAAWIWVPFLIIFTLAAWFFMNDLSASKASLSEQLPVLKRLHLWIMALLYLATFGSFIGFSAGFAMLSKTQFPDVQILHYAFFGPFIGALARSMGGAISDRLGGTRVTLVNFVVMAVFCALLFLTLPTNGQGGNFIAFFAVFMVLFLTAGLGSASTFQMISVIFRKLTMDRVKAQGGSEAQAMREAATDTAAALGFISAIGAIGGFFIPKAFGISLDLTGSPAGAMKVFLVFYIACVVITWAVYGRKRQ
>NZ_CP018447.1|WP_004175566.1|2224113_2225892_-|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX
MLKRLFTPLTLVNQLALIVLLATIIGVAGMAISARLVNGVQGSAHAINKAGSLRMQSYRLLAAIPLNENDQKLVADMTATVFSPELQNSARRDGQEIQLKALQQYWQLALAPGMQRAVNQAEVAQDVADFVDRIDQLVTAFDHTTEQRIERVVWIHRILAIGMALLLIFTIIWLRARLLRPWKQLLSMARAVSQRDFTQRAHISGRNEMATLGMALNNMSEELAESYAVLERRVQEKTAGLEQKNEILAFLWQANRRLHSSAPLCERISPVLNGLQGLTLLRDIEVRVYDLEDEDNHQEFTCHSDDDCDDKGCYLCPRNLPPLPDGGTTLKWRLSDAHSQYGILLATLPVGRHLSHDQQQLVDTLVEQLTSTLALDRHQEKQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPTESRQLLGQIRNELNTSWAQLRELLTTFRLQLTEPGLRPALEASCQEYSAHFGFTVQLDYQLPPRFVPSHQAIHLLQIAREALSNALKHASATEVTVTVSQRDNQVRLVVADNGRGVPDHAERSNHYGLIIMRDRAQSLRGDCQVRRRETGGTEVIVTFIPEKTFSIQ
>NZ_CP018447.1|WP_002910198.1|2223452_2224103_-|two-component-system-response-regulator-NarL
MSQQERATILLIDDHPMLRTGVKQLISMAPDIQVIGEASNGAQGIELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRVVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALQQAAAGEMVLSEALTPVLAASLRANRATSDRDISQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF
>NZ_CP018447.1|WP_004151854.1|2237180_2238023_-|formyltetrahydrofolate-deformylase
MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFNDATLLADLDSALPEGSIRELNPAGRRRVVILVTKEAHCLGDLLMKANYGGLDVDIAAVIGNHDTLRSLVERFGIPFELVSHEGLSREEHDQRMGDAIAAHEPDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYQVLAQRVFVYGNRTIIL
>NZ_CP018447.1|WP_002910109.1|2238065_2238524_-|YchJ-family-protein
MSQLCPCGSALEYSSCCQRYLSGAELAPGPSQLMRSRYSAFVMKDADYLIKTWHPSCQAQQFRAELEKGFSQTEWLGLTLFASDEGRAPNEGFVSFVARFNDNNRPGAIIERSRFLKENGQWYYIDGTRPLIGRNDPCPCGSGKKFKKCCGQ
>NZ_CP018447.1|WP_002910108.1|2238636_2239539_+|patatin-like-phospholipase-RssA
MRKLKIGLALGAGAARGWSHIGVINALQRAGIEIDIVAGCSIGSLVGAAYACNRLPALESWVCSFSNWDVLKLMDLSWRRGGLLRGEKVFNHYRRIMPVTEIERCERRFAAVATNLSTGRELWFTEGDLHLAIRASCSMPGLMSPVRHNGYWLVDGAVVNPVPVSLTRAMGADIVIAVDLQHDAHLMQQDLFSLETPRQEAEEKEGPWHTRLRARLTRMSSRRTAVTPTAMEIMTTSIQVLENRLKRNRMAGDPPDILLQPYCPQVSTLDFHRAGEAIAAGQLAVEKKMDELLPLVRTAV
>NZ_CP018447.1|WP_002910107.1|2239628_2240642_+|two-component-system-response-regulator-RssB
MTQPLAGKQILIVEDEPVFRSLLHGWLTSLGATTFQAEDGKDALHKMTEVHPDLMICDISMPRMNGLELVETLRNRGEQLPILMISATENMADIAKALRLGVQDVLLKPVKDFDRLRETVYACLYPAMFSSRVEEEERLFEDWDALVSNPIAASRLLQELQPPVQQEMSHCRIHYRQLVSADKPGLVLDIAPLSENDLAFYCLDVTRAGDNGVLAALLLRALFNGLLQEQLAHQGQRLPEMGSLLKQVNQLLRQANLPGQFPLLVGYYHSGLKNLILVSAGLNGTLNTGEHQIQISNGVPLGTLGDAYLNQISQRCTSWQCQIWGAGGRLRLMLSAE
>NZ_CP018447.1|WP_002910105.1|2240839_2241742_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MAALNSKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLEEVQSICPPHVTIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSRDNLAEMISRFDETGASQIMVEPVEDVTAYGVVDCKGESLKPGESVPMVGVVEKPKADVAPSNLAVVGRYVLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHKTLGDDFKAWLETAVAK
>NZ_CP018447.1|WP_002910103.1|2241863_2242271_-|DNA-binding-transcriptional-regulator-H-NS
MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEENAAAAEIEERTRKLQQYREMLIADGIDPNELLSTMAAVKAGTKTKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLI
>NZ_CP018447.1|WP_004145401.1|2242693_2242825_-|hypothetical-protein
MTPIKVFYRGDDCTIFYAHSRAFSRGIVAKLKGLQTERIKKMN
>NZ_CP018447.1|WP_002910100.1|2242832_2243450_+|thymidine-kinase
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLYNPQTSLFDDIAAEHQLKPIHCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDFRGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEGRPYNEGEQVVIGGNERYVSVCRKHYKEALSVGSLTKVQNQHRPC
>NZ_CP018447.1|WP_002910097.1|2243597_2246273_-|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MAVTNIAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKEATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGALNAAIVGQPAAKIAELAGFTVPATTKILIGEVTNVDESEPFAHEKLSPTLAMYRAKDFEDAVAKAEKLVAMGGIGHTSCLYTDQDNQPARVAYFGQMMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLTIVRKGADLANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMVAITTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHALEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLESIKAELGIPKSIREAGVQEADFLAHVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGREFVEGEAGAKAEVAPVKAEKKAKKSA
>NZ_CP018447.1|WP_032103886.1|2246350_2246536_+|hypothetical-protein
MHVNVYVEKSGRCFTDLLKKLYLFRFQVLLPSTLLVSSRLLTSEYKLRDLDQVLSLLIPFS

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Crispr_ID: NZ_CP018447_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018447_4

4127467-4127562

Orphan

Consensus_repeat	Method
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018447_4

>merge|NZ_CP018447|4|4127467-4127562|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAACCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGTTGGCACTTTGTTGGCATTCTGTTGGCACAA

>NZ_CP018447|4|3|4127467-4127562|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGT
TGGCACTTTGTTGGCATTCTGTTGGCACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018447.1\|WP_023283341.1\|4121755_4122352_-\|DUF1367-family-protein	unknown	unknown	gnl\|CDD\|369209
NZ_CP018447.1\|WP_032419320.1\|4125122_4125347_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_032419316.1\|4120917_4121586_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277367
NZ_CP018447.1\|WP_032419508.1\|4131104_4131308_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_032419317.1\|4122510_4122825_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_024264476.1\|4121582_4121750_-\|NinE-family-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP018447.1\|WP_032419325.1\|4128777_4129488_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224885
NZ_CP018447.1\|WP_073546926.1\|4125636_4127052_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672
NZ_CP018447.1\|WP_001548453.1\|4128180_4128402_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|336083
NZ_CP018447.1\|WP_032419321.1\|4125343_4125637_-\|protein-ren	unknown	unknown	gnl\|CDD\|238042
NZ_CP018447.1\|WP_032419315.1\|4120286_4120925_-\|recombination-protein-NinG	unknown	unknown	gnl\|CDD\|368603
NZ_CP018447.1\|WP_032419324.1\|4127948_4128095_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_001548452.1\|4128481_4128673_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370262
NZ_CP018447.1\|WP_016529276.1\|4132022_4132307_+\|host-nuclease-inhibitor-GamL	unknown	unknown	unknown
NZ_CP018447.1\|WP_014342891.1\|4132716_4133052_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_009308003.1\|4123929_4124106_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_004191592.1\|4129860_4130916_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NZ_CP018447.1\|WP_032419318.1\|4124105_4124435_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018447.1\|WP_008807814.1\|4131735_4131942_+\|phage-encoded-cell-division-inhibitor-protein	unknown	unknown	gnl\|CDD\|236900
NZ_CP018447.1\|WP_004219883.1\|4131617_4131743_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP018447.1\|WP_023283341.1\|4121755_4122352_-\|DUF1367-family-protein	gnl\|CDD\|369209	pfam07105, DUF1367, Protein of unknown function (DUF1367). This family consists of several highly conserved, hypothetical phage proteins of around 200 residues in length. The function of this family is unknown. Some proteins are annotated as IrsA (intracellular response to stress).	9.36454e-79
NZ_CP018447.1\|WP_008807814.1\|4131735_4131942_+\|phage-encoded-cell-division-inhibitor-protein	gnl\|CDD\|236900	PRK11354, kil, FtsZ inhibitor protein; Reviewed.	1.49968e-15
NZ_CP018447.1\|WP_032419316.1\|4120917_4121586_-\|metallophosphoesterase	gnl\|CDD\|277367	cd07424, MPP_PrpA_PrpB, PrpA and PrpB, metallophosphatase domain. PrpA and PrpB are bacterial type I serine/threonine and tyrosine phosphatases thought to modulate the expression of proteins that protect the cell upon accumulation of misfolded proteins in the periplasm. The PPP (phosphoprotein phosphatase) family, to which PrpA and PrpB belong, is one of two known protein phosphatase families specific for serine and threonine. This family also includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	4.51085e-101
NZ_CP018447.1\|WP_024264476.1\|4121582_4121750_-\|NinE-family-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	8.28037e-21
NZ_CP018447.1\|WP_032419321.1\|4125343_4125637_-\|protein-ren	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	0.000519744
NZ_CP018447.1\|WP_073546926.1\|4125636_4127052_-\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	8.48784e-158
NZ_CP018447.1\|WP_001548453.1\|4128180_4128402_-\|hypothetical-protein	gnl\|CDD\|336083	pfam05269, Phage_CII, Bacteriophage CII protein. This family consists of several phage CII regulatory proteins. CII plays a key role in the lysis-lysogeny decision in bacteriophage lambda and related phages.	1.55058e-09
NZ_CP018447.1\|WP_032419325.1\|4128777_4129488_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	1.18184e-32
NZ_CP018447.1\|WP_032419315.1\|4120286_4120925_-\|recombination-protein-NinG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	5.05533e-56
NZ_CP018447.1\|WP_004191592.1\|4129860_4130916_+\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	8.46801e-12
NZ_CP018447.1\|WP_001548452.1\|4128481_4128673_-\|hypothetical-protein	gnl\|CDD\|370262	pfam09048, Cro, Cro. Members of this family are involved in the repression of transcription by binding as a homodimer to palindromic DNA operator sites in phage lambda: they repress genes expressed in early phage development and are necessary for the late stage of lytic growth. These proteins have a secondary structure consisting of three alpha-helices and three beta-sheets, and dimerize through interactions between the two antiparallel beta-strands.	8.72296e-22

>NZ_CP018447.1|WP_073546926.1|4125636_4127052_-|AAA-family-ATPase
MTPPHSIEAEQSVLGGLLLDDDNSERTQKVLSILKPESFYSRQHQVIFAEMRQMYRDHKPVDLLTLFDALDSKGLTETVGGFAYLAEMSKNTPSAANIVAYAMRVRETAMERYGIEKTTKAIELLYARNGMTAEQKFDAIQGLFTEITDHVKTGRRTGLRTFYDAVTDWSAEFDERLKPDGRSRGLSTGIRSLDELLGVKRIVRGSLFVIGARPKMGKTTLYTQMGVNCATVENEPALMFSLEMPEGQMVEKITAQKGRISPNLFYPDMTKDDYGYRGDWNGDLKKATGVMGALIDTNNLLIDDTPGISLAHVVAESRRIKRERGKVGMILVDYLTLMTADKAERNDLAYGLITKGLKTLAKELDCVVVLLTQLNRELEKRTNKRPLPSDSRDTGQIEQDCDYWLAIYREGAYDENANQSDTELLLRLNRHGETGVVYCEQRHGAIYDCDQEAASQRRREKEEKPTKRGGF
>NZ_CP018447.1|WP_032419321.1|4125343_4125637_-|protein-ren
MTGKDAILNYLKTHKTCSSPDVAAASGMTHTCINQAANILAKQGVLVAEARVWRTVYYRLATEEEIAGKKSTNQIFNECRQSPAMKRVLAVYGRAQA
>NZ_CP018447.1|WP_032419320.1|4125122_4125347_-|hypothetical-protein
MKFIKLSQRGTVERQGKYGWEPETVYEPVFVAAGHIVSMFFAGVTILKTTSGERIDVKETPEEIIAMLTEGSAK
>NZ_CP018447.1|WP_032419318.1|4124105_4124435_-|hypothetical-protein
MTDITELAQRVERIISDVKLKHGGNDTYAPIMKWDEFSALVEALEKAQQRIAKLESRTVNVKLPTTIEPTAFSPWVAKAFYQFHKDTVKSCFAVFSDACAAAGIKVEVE
>NZ_CP018447.1|WP_009308003.1|4123929_4124106_-|hypothetical-protein
MFKIESSEQRLKRVLTENAGKFTIDEDGGIHTNWQHPEVQATMRRHFEALSKIKVDRK
>NZ_CP018447.1|WP_032419317.1|4122510_4122825_-|hypothetical-protein
MAELRAGCQAMIIGGFYRTNDGKAVLVAGFVPNGSRFTWNGEVYAEPVPMGDAWLVSGDLVARDGSTGEAKRMDFALMPAKYLMPIDGDDFSNEDQRQKEREYA
>NZ_CP018447.1|WP_023283341.1|4121755_4122352_-|DUF1367-family-protein
MAQTLQFEKSYQNVLIPAEPGTSEYLQLIPVGQLLCGEFRKPRNYAFHKKFFKLLTLGYHYWTPSGGLIEPAERTLISGFIDFLSSDLDQRAALQNASEMYLSSVGISRSRDMALLKHFESFREWATIQAGFYDEYQMPDGSRRRVAKSISFASMDDSQFNGVYKSVLNVLWNYILRRKFHSPAEAENAASQLLSFAG
>NZ_CP018447.1|WP_024264476.1|4121582_4121750_-|NinE-family-protein
MQCLLAKVMERGIFRVPARRKRKVEVKPSDIPTFHYTAHLADVRWLRRAARRKIA
>NZ_CP018447.1|WP_032419316.1|4120917_4121586_-|metallophosphoesterase
MSLYQSINGARWRSIWVVGDLHGCHTLLMKELEKVRFDPSCDLLISVGDLIDRGAENVECLELIAMPWFKAVRGNHEQMMLDGLSSSGNVNHWLANGGGWFFNLDYDKERLAIALAHLVAGLPLIIEVMTEGKKVVVCHADYPHNEYSYGKPVDAEQVIWNRERVSAAQDGIVNEISGADLFIFGHTPAHQPSQYANQMYIDTGAVFCGRLTLVQIQGGEHA
>NZ_CP018447.1|WP_032419315.1|4120286_4120925_-|recombination-protein-NinG
MRKPSRRKCAHCREWFHPAREGQVVCSFECASAIGKKQTAKAREAAKARAVKRQRESEKEGRQRRRAKRESFKTKAQWDKEAQSAFNRYIRIRDEGKPCVSCGNPLIGKSNYLTGSAIDASHYRSRGAASHLKFNVFNVHSACTRCNRQLSGNAVEYRIHLIERIGLDRVERLEADNEPRRFDIPYLQRIKSIFTRRSRALEKRRARHQEAA
>NZ_CP018447.1|WP_032419324.1|4127948_4128095_-|hypothetical-protein
MPKSNRFYQAQTHKNVTRDRFIRSVNPVVGMKMRAILEELKRKESGRE
>NZ_CP018447.1|WP_001548453.1|4128180_4128402_-|hypothetical-protein
MESSTTRNKVEARRIESWLHSQIAELGTTNIAKVAGVNKSTVSRWRESLLPNMSLLLAILISNRPGEKGDFEA
>NZ_CP018447.1|WP_001548452.1|4128481_4128673_-|hypothetical-protein
MKISLAEYVDEVGQARAADAIGVHQTAISKAIRVGRKIFVNTLPDGKIKAEEIKPFPHNRNPD
>NZ_CP018447.1|WP_032419325.1|4128777_4129488_+|helix-turn-helix-domain-containing-protein
MEKKKTLTSAQIADAERLKALYEAKKKELGITQQSIADMLDISQGGVGHYLNGRNALNAAVAAVFARALQVDVSDFSPSLAKEISVMSAAATSNAKYVGQYTPGIKYPVLSKIQAGHWSEACEPYALKDIDLWLESDAHIQGDAFWLLVEGESMTAPAGLSIPEGTYVLFDTGREPINGSLVIAKLSESNEATFKKLIIDGGQKYLKGLNPQWPMVPINGNCRIIGVAVETKLRLV
>NZ_CP018447.1|WP_004191592.1|4129860_4130916_+|ParA-family-protein
MTITAKQAAQGVDDTMKSYAIWNNKGGVGKTYLSFAMATEYARQNPEKRVIFADMCPQANLSEILLGGNGTGASRLAALIQQRKTIGGYFDRRTRSPHMITGAETSYLIHANETNSHIPANVFLIAGDPSLEVQAQVINQLSSVNLPVDSWKSIHLWLRDLLVACAQQQGIEDTVCFIDCNPSFSAYTELSLIAANAIIVPCSSDGSSARAVDNLSQLVYGVGVQNDYRAVNFYDRCLNFGISVPVIHSLVFNRSTEYDKRASKAFSAMFNEIMLRAENLRKIKPNSFQGGELKTFTVPDNHSVAIVSSHLGRPLFDITPGRYQIHDTEPQINNEPLERYGTAIKTLVQSL
>NZ_CP018447.1|WP_032419508.1|4131104_4131308_-|hypothetical-protein
MSNEDEFFAEMHPQIAQIIGMAVMQMLVEKREPSREALIEMIQVLWQGDQVDLSVELALDVLMLREE
>NZ_CP018447.1|WP_004219883.1|4131617_4131743_+|hypothetical-protein
MLGWQMSKQGIRSLIYCLLICGVIWTALIIKILHVTGVFNG
>NZ_CP018447.1|WP_008807814.1|4131735_4131942_+|phage-encoded-cell-division-inhibitor-protein
MVSHHYGTQTVNRGAVLPGMLVKHRESTWTASANKRGRLYLHRGIERTYTTDLLVEVYLNGLGQGLSR
>NZ_CP018447.1|WP_016529276.1|4132022_4132307_+|host-nuclease-inhibitor-GamL
MNAYRAYDAIEERKWAEQSLTEEKQKWIDDRAQEIIDALPKEPSGLFRFSVPMDKSPYEGLRSDAAGEAYNDLISAVAYAQAEYDWDHRTGCPF
>NZ_CP018447.1|WP_014342891.1|4132716_4133052_+|hypothetical-protein
MRPGEKLKPMILNATNSKMLKSITGSPFLEDWVGVKVTVYVDKNVRFGKESVEGLRLSPARVSKPVLSPEKTQAWNNAKAAFKRDGNLDAVLARMDISPEHRRQLEQECSA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP018447_2	2.1\|1770113\|40\|NZ_CP018447\|PILER-CR	1770113-1770152	40	NZ_CP018447.1	1770416-1770455	1	0.975
NZ_CP018447_2	2.2\|1770214\|40\|NZ_CP018447\|PILER-CR	1770214-1770253	40	NZ_CP018447.1	1770416-1770455	1	0.975

1. spacer 2.1|1770113|40|NZ_CP018447|PILER-CR matches to position: 1770416-1770455, mismatch: 1, identity: 0.975

taccccgattagttcgccatcccgtaggcctgataagcga	CRISPR spacer
taccccgattagttcgccattccgtaggcctgataagcga	Protospacer
********************.*******************

2. spacer 2.2|1770214|40|NZ_CP018447|PILER-CR matches to position: 1770416-1770455, mismatch: 1, identity: 0.975

taccccgattagttcgccatcccgtaggcctgataagcga	CRISPR spacer
taccccgattagttcgccattccgtaggcctgataagcga	Protospacer
********************.*******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP018447_4	4.1\|4127497\|36\|NZ_CP018447\|CRISPRCasFinder	4127497-4127532	36	MK448233	Klebsiella phage ST11-VIM1phi8.1, complete genome	8447-8482	1.0
NZ_CP018447_4	4.1\|4127497\|36\|NZ_CP018447\|CRISPRCasFinder	4127497-4127532	36	MK448235	Klebsiella phage ST512-KPC3phi13.1, complete genome	8447-8482	1.0
NZ_CP018447_4	4.1\|4127497\|36\|NZ_CP018447\|CRISPRCasFinder	4127497-4127532	36	MK448231	Klebsiella phage ST101-KPC2phi6.1, complete genome	11383-11418	1.0

1. spacer 4.1|4127497|36|NZ_CP018447|CRISPRCasFinder matches to MK448233 (Klebsiella phage ST11-VIM1phi8.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

2. spacer 4.1|4127497|36|NZ_CP018447|CRISPRCasFinder matches to MK448235 (Klebsiella phage ST512-KPC3phi13.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

3. spacer 4.1|4127497|36|NZ_CP018447|CRISPRCasFinder matches to MK448231 (Klebsiella phage ST101-KPC2phi6.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1142498 : 1208965

Salmonella_phage(76.09%)

lysis,terminase,integrase,head,portal,plate,tRNA,tail,capsid

attL 1162299:1162345|attR 1197591:1197637

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032418442.1\|1142498_1143374_-\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_071844616.1\|1144327_1144492_+	type II toxin-antitoxin system CcdA family antitoxin	NA	NA	NA	NA
WP_032418443.1\|1145335_1146694_-	adenylate/guanylate cyclase domain-containing protein	NA	NA	NA	NA
WP_123836165.1\|1146703_1147249_-	hypothetical protein	NA	NA	NA	NA
WP_032418444.1\|1147270_1147720_-	phage virion morphogenesis protein	O80313	Escherichia_phage	1.8e-44	63.8
WP_032418445.1\|1148093_1148252_-	hypothetical protein	A0A218M4L1	Erwinia_phage	3.2e-12	68.0
WP_071844617.1\|1148736_1148943_-	hypothetical protein	A0A1B5FPB7	Escherichia_phage	7.4e-09	55.3
WP_032418447.1\|1149383_1150397_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_032418448.1\|1150407_1151388_-	PTS glucitol/sorbitol transporter subunit IIB	NA	NA	NA	NA
WP_032418449.1\|1151384_1151759_-	PTS glucitol/sorbitol transporter subunit IIA	NA	NA	NA	NA
WP_032418451.1\|1151755_1152277_-	PTS glucitol/sorbitol transporter subunit IIC	NA	NA	NA	NA
WP_032418453.1\|1152389_1152674_-	transcriptional regulator	A0A2I7S995	Vibrio_phage	4.6e-17	64.7
WP_087757875.1\|1152768_1153125_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_073546842.1\|1153443_1155513_-	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	8.7e-73	34.6
WP_032418458.1\|1155548_1155764_-	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_032418459.1\|1156245_1160049_-	DNA-binding protein	NA	NA	NA	NA
WP_032418460.1\|1160237_1160885_-	hypothetical protein	NA	NA	NA	NA
WP_032418461.1\|1160886_1162134_-\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	8.5e-140	61.8
1162299:1162345	attL	NA	NA	NA	NA
WP_032418462.1\|1162430_1163477_-	hypothetical protein	NA	NA	NA	NA
WP_000155498.1\|1163466_1164507_-\|integrase	site-specific integrase	A0A1S6L016	Salmonella_phage	1.7e-189	92.7
WP_031591564.1\|1164510_1165143_-	helix-turn-helix domain-containing protein	A0A1S6KZZ7	Salmonella_phage	3.8e-64	57.1
WP_000102105.1\|1165259_1165502_+	Rha family transcriptional regulator	A0A1S6KZZ6	Salmonella_phage	6.8e-38	97.5
WP_031591568.1\|1165534_1166044_+	phage regulatory CII family protein	E5G6L3	Salmonella_phage	3.9e-83	94.7
WP_000956190.1\|1166051_1166252_+	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	2.4e-33	100.0
WP_031591570.1\|1166215_1166557_+	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	1.7e-55	97.3
WP_016529331.1\|1166624_1166858_+	DUF2732 family protein	E5G6L6	Salmonella_phage	1.2e-31	96.1
WP_031591572.1\|1166857_1167085_+	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	3.0e-35	97.3
WP_031591574.1\|1167081_1167939_+	DNA adenine methylase	E5G6L8	Salmonella_phage	1.1e-159	96.1
WP_031591576.1\|1167935_1170350_+	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	98.6
WP_001154434.1\|1170503_1170692_+	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_001217575.1\|1170702_1170936_+	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_000700647.1\|1171050_1171728_+	hypothetical protein	NA	NA	NA	NA
WP_000497736.1\|1172006_1173158_+	TIGR02391 family protein	NA	NA	NA	NA
WP_032418464.1\|1173209_1174244_-\|portal	phage portal protein	E5G6M3	Salmonella_phage	5.9e-171	87.3
WP_031591583.1\|1174243_1176010_-\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.1
WP_002895967.1\|1176152_1176986_+\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	6.3e-123	88.8
WP_031591585.1\|1177002_1178061_+\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	1.9e-180	93.1
WP_000059191.1\|1178064_1178715_+\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
WP_031591589.1\|1178810_1179275_+\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	1.1e-76	89.0
WP_031591593.1\|1179274_1179478_+\|tail	tail protein X	E5G6M9	Salmonella_phage	5.2e-31	91.0
WP_000171568.1\|1179481_1179697_+	hypothetical protein	E5G6N0	Salmonella_phage	1.8e-26	80.3
WP_031591597.1\|1179677_1180193_+	lysozyme	E5G6N1	Salmonella_phage	4.0e-88	91.8
WP_031591599.1\|1180189_1180618_+\|lysis	LysB family phage lysis regulatory protein	E5G6N2	Salmonella_phage	1.5e-59	91.5
WP_001039947.1\|1180713_1181145_+\|tail	phage tail protein	E5G6N3	Salmonella_phage	1.3e-71	93.0
WP_031591600.1\|1181137_1181602_+	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	5.5e-60	83.6
WP_031591601.1\|1181689_1183201_+	hypothetical protein	NA	NA	NA	NA
WP_031591602.1\|1183327_1183906_+\|plate	phage baseplate assembly protein V	A0A1S6KZX7	Salmonella_phage	1.6e-93	86.5
WP_031591604.1\|1183902_1184262_+	GPW/gp25 family protein	A0A1S6KZZ4	Salmonella_phage	9.5e-52	86.6
WP_031591606.1\|1184248_1185157_+\|plate	baseplate assembly protein	A0A1S6KZY6	Salmonella_phage	4.6e-143	90.4
WP_001086836.1\|1185149_1185755_+\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.5e-110	92.5
WP_031591609.1\|1185751_1187473_+\|tail	phage tail protein	M1TAS6	Escherichia_phage	3.5e-152	78.9
WP_050486392.1\|1187472_1187655_+	hypothetical protein	NA	NA	NA	NA
WP_077255116.1\|1187635_1187788_-\|tail	tail fiber assembly protein	U5P083	Shigella_phage	5.8e-11	71.1
WP_032418466.1\|1188451_1189018_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.1e-85	85.2
WP_031591343.1\|1189160_1190333_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	2.5e-202	89.2
WP_001504081.1\|1190342_1190858_+\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	4.8e-89	94.7
WP_001281009.1\|1190912_1191215_+\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	5.3e-40	89.0
WP_000763311.1\|1191229_1191349_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.8e-13	87.2
WP_032418469.1\|1191341_1194419_+\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	63.3
WP_016529761.1\|1194415_1194901_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	4.8e-67	80.6
WP_032418471.1\|1194897_1195998_+	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	4.2e-175	86.9
WP_000972389.1\|1196088_1196307_+	ogr/Delta-like zinc finger family protein	Q53ZE7	Salmonella_virus	1.9e-18	71.9
WP_000380485.1\|1196568_1196742_+	hypothetical protein	NA	NA	NA	NA
WP_031591352.1\|1196710_1197484_+	RNA-directed DNA polymerase	NA	NA	NA	NA
WP_002914164.1\|1198098_1198581_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.3e-29	47.4
1197591:1197637	attR	NA	NA	NA	NA
WP_071549035.1\|1198691_1199168_+	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_004145682.1\|1199157_1199448_+	RnfH family protein	NA	NA	NA	NA
WP_002914160.1\|1199514_1199856_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_004174799.1\|1200003_1201665_-	DNA repair protein RecN	NA	NA	NA	NA
WP_002914158.1\|1201751_1202630_-	NAD(+) kinase	NA	NA	NA	NA
WP_004174800.1\|1202754_1203345_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_004149392.1\|1203465_1204752_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_002914153.1\|1204771_1205563_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_002914152.1\|1205726_1207091_+	signal recognition particle protein	NA	NA	NA	NA
WP_002914149.1\|1207350_1207599_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_004150977.1\|1207617_1208166_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_073546843.1\|1208197_1208965_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA

DBSCAN-SWA_2

1310943 : 1325748

Morganella_phage(22.22%)

integrase

attL 1295806:1295821|attR 1330981:1330996

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1295806:1295821	attL	NA	NA	NA	NA
WP_029602776.1\|1310943_1312212_+\|integrase	site-specific integrase	A0A1W6JPG6	Morganella_phage	3.3e-147	60.8
WP_004866318.1\|1312219_1313173_+	hypothetical protein	NA	NA	NA	NA
WP_004866314.1\|1313299_1313518_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_029602778.1\|1313517_1313949_+	hypothetical protein	A0A1W6JPH9	Morganella_phage	3.1e-25	48.9
WP_032730932.1\|1313962_1314772_+	antA/AntB antirepressor family protein	A0A0R6PJV6	Moraxella_phage	3.5e-30	54.5
WP_073546847.1\|1314764_1314944_+	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_110109932.1\|1315590_1315785_+	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_004213164.1\|1315777_1315957_+	hypothetical protein	NA	NA	NA	NA
WP_032418506.1\|1315953_1316457_+	hypothetical protein	NA	NA	NA	NA
WP_032418508.1\|1316453_1316663_+	hypothetical protein	NA	NA	NA	NA
WP_032418509.1\|1316659_1317286_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.8e-26	37.8
WP_032418510.1\|1317295_1317646_+	hypothetical protein	A0A1B5FPL8	Escherichia_phage	8.9e-39	69.1
WP_032418512.1\|1317638_1320089_+	toprim domain-containing protein	Q7M2A8	Enterobacteria_phage	1.1e-138	38.0
WP_048265897.1\|1320396_1320795_+	hypothetical protein	NA	NA	NA	NA
WP_032418513.1\|1320791_1321238_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_055314482.1\|1321251_1321524_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_162900878.1\|1321593_1321914_+	superinfection immunity protein	A0A0S2SY85	Pseudomonas_phage	3.9e-17	45.4
WP_032421631.1\|1321943_1322321_+	hypothetical protein	A0A0M4QWT0	Salmonella_phage	1.1e-21	44.7
WP_004140789.1\|1322615_1322942_+	hypothetical protein	NA	NA	NA	NA
WP_073546849.1\|1322949_1325748_+	tape measure protein	A0A1B1W284	Salmonella_phage	7.7e-48	32.4
1330981:1330996	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1333744 : 1368256

Salmonella_phage(44.44%)

integrase,tail,terminase

attL 1334210:1334223|attR 1338891:1338904

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032418525.1\|1333744_1335211_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	1.5e-87	38.7
1334210:1334223	attL	NA	NA	NA	NA
WP_004151979.1\|1335278_1336856_+	glutamine-hydrolyzing GMP synthase	NA	NA	NA	NA
WP_032418526.1\|1337047_1338301_+\|integrase	site-specific integrase	A0A1X9TCT6	Enterobacter_phage	3.5e-202	83.6
WP_032418527.1\|1338562_1339225_-	metallophosphoesterase	K7P6H8	Enterobacteria_phage	4.7e-97	75.5
1338891:1338904	attR	NA	NA	NA	NA
WP_032418529.1\|1339221_1339824_-	adenine methylase	A0A193GYV6	Enterobacter_phage	4.0e-103	92.4
WP_023285452.1\|1339820_1340327_-	hypothetical protein	NA	NA	NA	NA
WP_009485474.1\|1340323_1340482_-	DUF1317 family protein	T1SAR0	Salmonella_phage	8.7e-18	80.8
WP_009485475.1\|1340474_1340768_-	PerC family transcriptional regulator	T1S9J5	Salmonella_phage	4.0e-32	71.1
WP_004144294.1\|1340877_1341126_-	AlpA family phage regulatory protein	A0A0F6TJ45	Escherichia_coli_O157_typing_phage	2.8e-31	78.0
WP_032418530.1\|1341176_1342199_-	recombination protein RecT	Q858E1	Salmonella_phage	4.0e-180	95.3
WP_004144292.1\|1342208_1343108_-	YqaJ viral recombinase family protein	Q858E0	Salmonella_phage	6.5e-158	91.0
WP_004164029.1\|1343104_1343404_-	hypothetical protein	A0A0F6R7M4	Escherichia_coli_O157_typing_phage	2.1e-20	54.5
WP_004164037.1\|1343400_1343550_-	hypothetical protein	G9L6A5	Escherichia_phage	7.9e-13	84.2
WP_004144290.1\|1343770_1344352_-	helix-turn-helix transcriptional regulator	Q858D7	Salmonella_phage	7.1e-65	64.3
WP_004152538.1\|1344506_1344740_+	hypothetical protein	T1SAR5	Salmonella_phage	9.2e-24	66.2
WP_004152537.1\|1344886_1345096_+	hypothetical protein	A0A193GYW4	Enterobacter_phage	1.8e-26	78.3
WP_004207253.1\|1345095_1345863_+	hypothetical protein	A0A193GZ86	Enterobacter_phage	8.9e-140	91.4
WP_032418532.1\|1345859_1346645_+	replication protein	A0A193GYX1	Enterobacter_phage	3.7e-133	87.7
WP_032418534.1\|1346764_1347112_+	DUF1064 domain-containing protein	A0A0F6R8N5	Escherichia_coli_O157_typing_phage	1.9e-49	81.7
WP_032419436.1\|1347304_1347706_+	hypothetical protein	A0A2H4N7F5	Pectobacterium_phage	8.7e-22	51.6
WP_025860565.1\|1347777_1347987_+	hypothetical protein	NA	NA	NA	NA
WP_032418536.1\|1347983_1348238_+	hypothetical protein	NA	NA	NA	NA
WP_032419437.1\|1348237_1348501_+	hypothetical protein	A0A2P0P958	Salmonella_phage	3.5e-27	65.5
WP_032418538.1\|1349194_1349434_+	hypothetical protein	G8C7S3	Escherichia_phage	8.6e-09	51.7
WP_032418539.1\|1349433_1349772_+	hypothetical protein	A0A193GYX4	Enterobacter_phage	3.1e-44	79.1
WP_032418540.1\|1349846_1350104_+	hypothetical protein	NA	NA	NA	NA
WP_032418541.1\|1350181_1350766_+\|terminase	terminase small subunit	T1SBI8	Salmonella_phage	9.9e-91	88.6
WP_032418542.1\|1350762_1352238_+	hypothetical protein	Q858H3	Salmonella_phage	2.4e-279	92.4
WP_032413826.1\|1352280_1352652_-	phage family protein	A0A0F6TJP2	Escherichia_coli_O157_typing_phage	6.8e-61	93.5
WP_004152472.1\|1353449_1353653_+	hypothetical protein	NA	NA	NA	NA
WP_004149313.1\|1353656_1355336_+\|tail	tail protein	T1S9Z7	Salmonella_phage	3.6e-194	59.3
WP_004152470.1\|1355332_1355638_+	hypothetical protein	Q2A090	Sodalis_phage	1.1e-16	51.3
WP_004152468.1\|1355919_1356318_+	peptidase	T1SAP9	Salmonella_phage	5.6e-37	59.5
WP_004197367.1\|1356330_1357338_+	bbp17	T1S9H9	Salmonella_phage	2.1e-181	92.8
WP_004152466.1\|1357347_1357740_+	hypothetical protein	T1SA71	Salmonella_phage	1.5e-55	89.9
WP_024622837.1\|1357732_1358011_+	hypothetical protein	T1SA01	Salmonella_phage	1.1e-20	58.9
WP_004197381.1\|1358059_1358671_+	hypothetical protein	T1SAQ2	Salmonella_phage	9.2e-47	48.8
WP_032418543.1\|1358670_1361148_+	hypothetical protein	G9L6D0	Escherichia_phage	2.3e-266	56.4
WP_032418545.1\|1361149_1361620_+	hypothetical protein	Q858G2	Salmonella_phage	9.5e-44	55.3
WP_025860587.1\|1361612_1362110_+	hypothetical protein	A0A0F6TJ56	Escherichia_coli_O157_typing_phage	8.9e-24	41.7
WP_032418548.1\|1362122_1364867_+	bacteriophage protein	A0A193GYI3	Enterobacter_phage	3.9e-97	39.7
WP_032418549.1\|1364866_1368256_+	hypothetical protein	G9L6D4	Escherichia_phage	2.4e-120	42.0

DBSCAN-SWA_4

1790818 : 1799197

Enterobacteria_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032418677.1\|1790818_1792225_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	1.8e-37	28.7
WP_032418679.1\|1792447_1793512_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.4e-105	55.0
WP_004175258.1\|1793538_1794408_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	5.7e-111	67.0
WP_004175259.1\|1794439_1795330_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.8e-28	34.2
WP_021313307.1\|1795344_1795899_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	1.9e-51	57.6
WP_004175261.1\|1796078_1797245_+	UDP-glucose 6-dehydrogenase	M1I798	Paramecium_bursaria_Chlorella_virus	4.1e-112	54.7
WP_032409012.1\|1797670_1797793_-	small membrane protein	NA	NA	NA	NA
WP_004175262.1\|1798192_1799197_-	NAD-dependent epimerase	E3T4Y8	Cafeteria_roenbergensis_virus	1.8e-31	29.5

DBSCAN-SWA_5

1922431 : 2056500

149

Enterobacteria_phage(23.33%)

capsid,integrase,holin,portal,head,plate,tRNA,protease,tail,terminase

attL 1975194:1975212|attR 2012942:2012960

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000059623.1\|1922431_1923694_-\|integrase	tyrosine-type recombinase/integrase	A0A1B0VMI6	Pseudomonas_phage	4.8e-74	39.3
WP_002911729.1\|1924261_1925179_+	nitrogen assimilation transcriptional regulator	NA	NA	NA	NA
WP_032418726.1\|1925285_1926236_+	HTH-type transcriptional regulator Cbl	NA	NA	NA	NA
WP_064147810.1\|1926314_1927256_+	L,D-transpeptidase	NA	NA	NA	NA
WP_004141160.1\|1927634_1928555_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002911718.1\|1928695_1929085_+	RidA family protein	NA	NA	NA	NA
WP_004227143.1\|1929750_1930551_-	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_004184758.1\|1930843_1931836_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	4.9e-175	87.2
WP_032418728.1\|1931837_1932065_-	DUF4224 domain-containing protein	Q8HAA9	Salmonella_phage	3.8e-30	78.4
WP_050598702.1\|1932372_1933281_-	DUF550 domain-containing protein	S4TSR6	Salmonella_phage	9.8e-45	61.6
WP_055314381.1\|1933273_1934350_-	DGQHR domain-containing protein	T1SBJ4	Salmonella_phage	2.1e-147	74.1
WP_032418730.1\|1934477_1935263_-	hypothetical protein	A4JX52	Burkholderia_virus	1.4e-60	50.2
WP_032418731.1\|1935262_1935562_-	hypothetical protein	K7PJS4	Enterobacterial_phage	3.8e-14	46.7
WP_032418732.1\|1935649_1936567_-	recombination-associated protein RdgC	A0A1W6JP69	Morganella_phage	3.1e-46	36.9
WP_016530207.1\|1937013_1937673_-	helix-turn-helix domain-containing protein	H9C160	Pectobacterium_phage	7.3e-74	62.7
WP_016530206.1\|1937765_1937963_+	Cro/Cl family transcriptional regulator	H9C161	Pectobacterium_phage	2.7e-16	66.1
WP_004213338.1\|1937988_1938450_+	hypothetical protein	K7PJS5	Enterobacterial_phage	1.7e-69	88.2
WP_001208720.1\|1938687_1938867_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	4.6e-15	73.1
WP_032418734.1\|1938856_1939825_+	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	1.0e-84	66.4
WP_032418735.1\|1940030_1940855_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1C9II58	Salmonella_phage	2.6e-113	69.5
WP_032418736.1\|1940864_1941242_+	RusA family crossover junction endodeoxyribonuclease	A0A1C9IIA0	Salmonella_phage	3.3e-47	72.8
WP_032418737.1\|1941254_1942235_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	8.4e-135	67.2
WP_032418738.1\|1942248_1942827_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.7e-50	56.7
WP_032418739.1\|1942978_1943218_+	hypothetical protein	NA	NA	NA	NA
WP_057182115.1\|1943388_1943688_+\|holin	phage holin family protein	A0A286N2Q5	Klebsiella_phage	1.5e-39	84.8
WP_032418741.1\|1943684_1944224_+	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	2.0e-101	98.9
WP_032418742.1\|1944220_1944568_+	hypothetical protein	A0A286N2Q7	Klebsiella_phage	2.1e-40	81.7
WP_032418743.1\|1944564_1944840_+	hypothetical protein	A0A286N2Q8	Klebsiella_phage	3.9e-05	70.3
WP_032418744.1\|1944790_1944985_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	4.6e-21	87.3
WP_022065473.1\|1945342_1945588_+	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	1.6e-34	98.8
WP_032419453.1\|1946099_1946450_+	HNH endonuclease	A0A1B5FP94	Escherichia_phage	4.6e-51	80.7
WP_004884285.1\|1946581_1947076_+\|terminase	phage terminase small subunit P27 family	Q8HAD7	Salmonella_phage	1.2e-81	92.0
WP_032418747.1\|1947072_1948803_+\|terminase	terminase large subunit	Q8HAD6	Salmonella_phage	9.2e-302	83.4
WP_004899640.1\|1948997_1950227_+\|portal	phage portal protein	U5P411	Shigella_phage	1.7e-201	81.5
WP_004884313.1\|1950213_1950867_+\|head,protease	HK97 family phage prohead protease	Q8W628	Enterobacteria_phage	2.1e-105	87.4
WP_021313628.1\|1950881_1952090_+\|capsid	phage major capsid protein	A0A192Y5T6	Salmonella_phage	9.9e-194	84.5
WP_021313627.1\|1952128_1952332_+	hypothetical protein	M1FN89	Enterobacteria_phage	1.4e-07	42.4
WP_021313626.1\|1952328_1952649_+\|head,tail	phage gp6-like head-tail connector protein	Q8SBH7	Shigella_phage	4.8e-15	43.1
WP_032408655.1\|1952657_1952996_+\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	1.4e-41	74.1
WP_019705270.1\|1952992_1953442_+	HK97 gp10 family phage protein	Q9MCS9	Enterobacteria_phage	6.7e-63	82.6
WP_016530186.1\|1953438_1953786_+	DUF3168 domain-containing protein	K7PKL6	Enterobacterial_phage	2.8e-32	63.7
WP_021313623.1\|1953842_1954547_+	immunoglobulin domain-containing protein	K7PHL2	Enterobacterial_phage	2.5e-80	66.9
WP_029497345.1\|1954577_1954982_+\|tail	phage tail protein	K7PKV6	Enterobacterial_phage	3.2e-32	56.9
WP_032418748.1\|1954984_1955290_+	DUF4035 domain-containing protein	Q9MCS5	Enterobacteria_phage	1.4e-27	63.6
WP_016530182.1\|1955363_1955597_+	hypothetical protein	K7PH16	Enterobacteria_phage	1.9e-08	47.2
WP_032418749.1\|1955657_1959044_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	2.5e-303	57.9
WP_023301979.1\|1959064_1959538_+	hypothetical protein	A0A286S298	Klebsiella_phage	4.6e-54	60.8
WP_021313618.1\|1959524_1960010_+	DUF1833 family protein	A0A286S2B1	Klebsiella_phage	3.0e-53	66.2
WP_021313617.1\|1960019_1960400_+	hypothetical protein	A0A286S2A6	Klebsiella_phage	2.1e-57	80.2
WP_032418750.1\|1960396_1963480_+	kinase	A0A286S259	Klebsiella_phage	0.0e+00	71.9
WP_032419560.1\|1965977_1966268_-	hypothetical protein	NA	NA	NA	NA
WP_057184564.1\|1966322_1968032_-	hypothetical protein	H6X4Y8	Enterobacteria_phage	1.2e-16	37.0
WP_032418751.1\|1968164_1968743_+	recombinase family protein	A0A286S1P7	Klebsiella_phage	2.2e-90	93.4
WP_004892499.1\|1968793_1969216_+	hypothetical protein	K7P834	Enterobacteria_phage	1.8e-25	44.5
WP_004216505.1\|1969627_1969867_+	hypothetical protein	I6PD82	Cronobacter_phage	7.5e-21	54.4
WP_032418752.1\|1969869_1970196_+	hypothetical protein	K7PGV5	Enterobacterial_phage	1.6e-26	53.9
WP_002911596.1\|1970799_1971945_-	porin OmpC	Q1MVN1	Enterobacteria_phage	1.1e-117	58.7
WP_004151461.1\|1972483_1972765_+	hypothetical protein	NA	NA	NA	NA
WP_002911594.1\|1972807_1973515_+	phosphohydrolase	S4W232	Pandoravirus	2.8e-07	27.7
WP_073546856.1\|1973591_1974992_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.9e-100	52.7
WP_032419454.1\|1974972_1975467_+	very short patch repair endonuclease	E5E3X5	Burkholderia_phage	9.7e-31	50.7
1975194:1975212	attL	NA	NA	NA	NA
WP_004184683.1\|1975441_1976353_-	drug/metabolite exporter YedA	NA	NA	NA	NA
WP_002911591.1\|1976536_1977448_+	DUF808 domain-containing protein	NA	NA	NA	NA
WP_032418754.1\|1977562_1979242_+	cellulose biosynthesis regulator YedQ	A0A127AWB9	Bacillus_phage	3.1e-20	41.1
WP_002911589.1\|1979541_1979763_-	YodD family protein	NA	NA	NA	NA
WP_002911586.1\|1979896_1980088_+	protein DsrB	NA	NA	NA	NA
WP_002911561.1\|1980120_1980744_-	transcriptional regulator RcsA	NA	NA	NA	NA
WP_004189223.1\|1981116_1981551_+	lipoprotein	NA	NA	NA	NA
WP_004189225.1\|1981592_1983080_-	alpha-amylase	NA	NA	NA	NA
WP_004141135.1\|1983280_1984081_+	cystine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004180445.1\|1984176_1985163_+	D-cysteine desulfhydrase	NA	NA	NA	NA
WP_002911547.1\|1985178_1985847_+	cystine ABC transporter permease	NA	NA	NA	NA
WP_004151455.1\|1985843_1986596_+	L-cystine ABC transporter ATP-binding protein YecC	G3M9Y6	Bacillus_virus	2.2e-26	34.4
WP_002911542.1\|1986913_1987636_+	transcriptional regulator SdiA	NA	NA	NA	NA
WP_002911541.1\|1987703_1987928_-	DUF2594 family protein	NA	NA	NA	NA
WP_002911539.1\|1988389_1989046_+	UvrY/SirA/GacA family response regulator transcription factor	NA	NA	NA	NA
WP_002911538.1\|1989042_1990875_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_002911537.1\|1990932_1991481_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_032418755.1\|1992054_1993062_-\|integrase	tyrosine-type recombinase/integrase	Q1I119	Pasteurella_virus	1.3e-103	56.5
WP_050598706.1\|1993058_1993925_-	hypothetical protein	NA	NA	NA	NA
WP_032418756.1\|1993941_1994571_-	membrane protein	NA	NA	NA	NA
WP_077261143.1\|1994580_1995009_-	helix-turn-helix transcriptional regulator	A0A2H4JFL3	uncultured_Caudovirales_phage	1.0e-07	38.5
WP_032418759.1\|1995281_1995485_+	hypothetical protein	P79674	Haemophilus_phage	6.4e-05	37.1
WP_050598721.1\|1995707_1995905_+	hypothetical protein	NA	NA	NA	NA
WP_032418760.1\|1995921_1996320_+	hypothetical protein	NA	NA	NA	NA
WP_032418761.1\|1996329_1996602_+	hypothetical protein	NA	NA	NA	NA
WP_032418762.1\|1996670_1996895_+	hypothetical protein	NA	NA	NA	NA
WP_032418763.1\|1996891_1997470_+	3'-5' exoribonuclease	A0A192Y6E0	Salmonella_phage	3.2e-33	41.1
WP_032418764.1\|1997478_1997706_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	5.5e-05	49.0
WP_032418765.1\|1997702_1997897_+	hypothetical protein	NA	NA	NA	NA
WP_032418766.1\|1997889_1998843_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A0M4QWR0	Salmonella_phage	3.6e-82	56.3
WP_162900880.1\|1998842_1999016_+	hypothetical protein	NA	NA	NA	NA
WP_156851987.1\|1999026_1999182_+	hypothetical protein	NA	NA	NA	NA
WP_032418767.1\|1999157_2000174_+	DNA cytosine methyltransferase	Q6J1P4	Burkholderia_virus	1.9e-97	55.1
WP_032418768.1\|2000166_2002761_+	replication endonuclease	A0A0M4RTM8	Salmonella_phage	1.2e-196	52.4
WP_032418769.1\|2002957_2003959_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_032418771.1\|2004694_2005741_-\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	5.8e-142	69.1
WP_032418772.1\|2005740_2007462_-	helix-turn-helix domain-containing protein	A0A0A7NV54	Enterobacteria_phage	6.2e-226	66.2
WP_032418773.1\|2007622_2008456_+\|capsid	GPO family capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	1.1e-95	65.6
WP_032418774.1\|2008480_2009530_+\|capsid	phage major capsid protein, P2 family	A0A0M3ULA3	Salmonella_phage	5.7e-105	55.0
WP_032418775.1\|2009577_2010477_+\|terminase	terminase	B9A7B6	Serratia_phage	3.5e-87	77.0
WP_032418776.1\|2010579_2011077_+\|head	head completion/stabilization protein	B9A7B7	Serratia_phage	1.2e-60	71.5
WP_032418777.1\|2011076_2011277_+\|tail	tail protein X	A0A0A7NV57	Enterobacteria_phage	6.7e-15	64.6
WP_032418778.1\|2011267_2011549_+	hypothetical protein	B9A7B8	Serratia_phage	1.1e-18	57.1
WP_032418779.1\|2011545_2012097_+	lysozyme	Q1I0Z1	Pasteurella_virus	9.2e-30	41.3
WP_050598707.1\|2012093_2012489_+	DUF2570 domain-containing protein	NA	NA	NA	NA
WP_032418780.1\|2012633_2013092_+\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	6.2e-32	48.1
2012942:2012960	attR	NA	NA	NA	NA
WP_032418781.1\|2013088_2013730_+	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	1.5e-44	48.3
WP_032418782.1\|2013729_2014308_+\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	5.1e-63	62.6
WP_032418783.1\|2014304_2014673_+	GPW/gp25 family protein	A0A0A7NQ90	Enterobacteria_phage	2.3e-29	58.3
WP_032418784.1\|2014659_2015559_+\|plate	baseplate J/gp47 family protein	A0A0A7NPY5	Enterobacteria_phage	6.2e-92	60.9
WP_032418785.1\|2015551_2016148_+\|tail	phage tail protein I	A0A0M4R4W9	Salmonella_phage	1.5e-41	46.3
WP_032418787.1\|2019531_2020689_+\|tail	phage tail protein	S4TP62	Salmonella_phage	2.5e-45	49.8
WP_032418788.1\|2020816_2021305_-\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	1.6e-49	65.0
WP_032418789.1\|2021316_2024256_-\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	2.6e-208	44.2
WP_101972624.1\|2024236_2024413_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.5e-10	69.8
WP_032418790.1\|2024409_2024709_-	hypothetical protein	B9A7B2	Serratia_phage	3.1e-32	73.7
WP_032418791.1\|2024763_2025279_-\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	2.6e-63	70.0
WP_032418792.1\|2025278_2026460_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A7NV69	Enterobacteria_phage	1.2e-156	69.3
WP_032418793.1\|2026613_2027768_+	phage late control D family protein	B9A7A9	Serratia_phage	4.2e-178	80.7
WP_044785060.1\|2027812_2028061_+	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_004180444.1\|2028447_2029329_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_023316206.1\|2029427_2030096_+	YecA family protein	NA	NA	NA	NA
WP_004151453.1\|2030120_2031332_-	tyrosine transporter TyrP	NA	NA	NA	NA
WP_004175410.1\|2031523_2031763_+	YecH family protein	NA	NA	NA	NA
WP_004141101.1\|2031798_2032296_-	non-heme ferritin	NA	NA	NA	NA
WP_020956668.1\|2032353_2032533_-	hypothetical protein	NA	NA	NA	NA
WP_002911524.1\|2034396_2034648_+	DUF2766 domain-containing protein	NA	NA	NA	NA
WP_002911522.1\|2034685_2036197_-	MFS transporter	NA	NA	NA	NA
WP_004148869.1\|2036262_2036421_+	succinate dehydrogenase	NA	NA	NA	NA
WP_004175413.1\|2036491_2037001_-	non-heme ferritin-like protein	NA	NA	NA	NA
WP_160525722.1\|2037435_2037534_-	hypothetical protein	NA	NA	NA	NA
WP_002911518.1\|2037895_2038876_+	arabinose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_032418795.1\|2038938_2040453_+	L-arabinose ABC transporter ATP-binding protein AraG	A0A2R8FG22	Brazilian_cedratvirus	4.1e-11	30.0
WP_002911507.1\|2040467_2041448_+	L-arabinose ABC transporter permease AraH	NA	NA	NA	NA
WP_002911505.1\|2041609_2042398_+	trehalose-phosphatase	NA	NA	NA	NA
WP_004175414.1\|2042372_2043797_+	alpha,alpha-trehalose-phosphate synthase	NA	NA	NA	NA
WP_002911500.1\|2043820_2044249_-	universal stress protein UspC	NA	NA	NA	NA
WP_002911499.1\|2044602_2046186_+	MFS transporter	NA	NA	NA	NA
WP_004184668.1\|2046190_2047330_+	glycoside hydrolase family 105 protein	NA	NA	NA	NA
WP_004151452.1\|2047391_2049125_-\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	1.4e-87	33.8
WP_002911491.1\|2049360_2049930_+	VOC family protein	NA	NA	NA	NA
WP_032418796.1\|2050006_2050750_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_023316208.1\|2050831_2051836_-\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_002911486.1\|2051832_2052576_-	carboxy-S-adenosyl-L-methionine synthase CmoA	F5B419	Synechococcus_phage	4.1e-25	30.0
WP_002911484.1\|2052615_2053011_-	MAPEG family protein	NA	NA	NA	NA
WP_002911483.1\|2053063_2053882_-	DUF72 domain-containing protein	Q859D1	Escherichia_coli_phage	1.1e-60	82.7
WP_004145564.1\|2053878_2054445_-	hydrolase	NA	NA	NA	NA
WP_002911479.1\|2054712_2056500_+\|tRNA	aspartate--tRNA ligase	A0A2K9L3L6	Tupanvirus	1.3e-11	27.2

DBSCAN-SWA_6

2859661 : 2870548

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032419001.1\|2859661_2862769_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
WP_032419002.1\|2862823_2864089_+	oligosaccharide MFS transporter	NA	NA	NA	NA
WP_001620097.1\|2864119_2865208_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_004176262.1\|2865294_2865555_-	hypothetical protein	A0A077SK33	Escherichia_phage	5.4e-41	98.8
WP_001620095.1\|2865852_2866713_+	class A broad-spectrum beta-lactamase SHV-1	A0A077SL40	Escherichia_phage	4.4e-156	99.7
WP_002210513.1\|2866733_2867495_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002903955.1\|2867755_2868658_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_004224682.1\|2868669_2869935_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	7.8e-234	99.8
WP_002210516.1\|2869927_2870548_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_7

3571172 : 3580646

Brazilian_cedratvirus(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023158537.1\|3571172_3572894_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
WP_002898014.1\|3572938_3573640_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3573993_3574212_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002896522.1\|3574342_3576622_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_002896520.1\|3576652_3576970_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|3577295_3577517_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_032419142.1\|3577593_3579534_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_002896440.1\|3579530_3580646_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7

DBSCAN-SWA_8

4092316 : 4139961

Cronobacter_phage(26.92%)

terminase,holin,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032419291.1\|4092316_4094794_-	MoaD/ThiS family protein	F1C5A7	Cronobacter_phage	2.6e-196	45.3
WP_032419292.1\|4094780_4095176_-	C40 family peptidase	F1C5F2	Cronobacter_phage	3.6e-36	54.8
WP_032419293.1\|4095172_4095643_-	hypothetical protein	R9TPR6	Aeromonas_phage	9.6e-28	40.4
WP_032419294.1\|4095642_4096119_-	hypothetical protein	A0A2P1MXB5	Escherichia_phage	8.7e-37	48.4
WP_072032582.1\|4096232_4096496_+	DUF1883 domain-containing protein	NA	NA	NA	NA
WP_023339093.1\|4096475_4096655_-	hypothetical protein	NA	NA	NA	NA
WP_032419296.1\|4096695_4100109_-	tape measure protein	R9TMK1	Aeromonas_phage	6.0e-188	50.0
WP_050598715.1\|4100174_4101203_-	hypothetical protein	NA	NA	NA	NA
WP_023342743.1\|4101277_4101490_-	hemolysin XhlA family protein	H6WRV2	Salmonella_phage	1.0e-13	58.8
WP_032419298.1\|4102052_4102526_-	DUF2335 domain-containing protein	S5WJ01	Leptospira_phage	5.0e-08	26.5
WP_124038561.1\|4102494_4102692_-	hypothetical protein	NA	NA	NA	NA
WP_032419299.1\|4102792_4103071_-	hypothetical protein	NA	NA	NA	NA
WP_023297298.1\|4103131_4103647_-	KilA-N domain-containing protein	A0A1V0E5P7	Salmonella_phage	5.0e-62	70.7
WP_032419300.1\|4103864_4104578_-	hypothetical protein	G0ZNE7	Cronobacter_phage	3.3e-64	55.1
WP_064767745.1\|4104645_4105410_-	immunoglobulin domain-containing protein	G0ZNE6	Cronobacter_phage	1.2e-40	44.0
WP_023341847.1\|4105468_4105690_-	hypothetical protein	NA	NA	NA	NA
WP_073546890.1\|4105692_4106076_-	hypothetical protein	NA	NA	NA	NA
WP_073546891.1\|4106072_4106441_-	hypothetical protein	F1C5E3	Cronobacter_phage	2.9e-48	83.6
WP_073546892.1\|4106492_4107047_-	HNH endonuclease	A0A2I7S010	Vibrio_phage	4.3e-35	39.7
WP_040229587.1\|4107144_4107507_-	hypothetical protein	G0ZNE2	Cronobacter_phage	4.3e-28	52.5
WP_048336937.1\|4107506_4107680_-	hypothetical protein	I6R0P9	Salmonella_phage	4.1e-13	54.4
WP_073546893.1\|4107679_4108060_-	hypothetical protein	F1C5E2	Cronobacter_phage	1.8e-29	55.3
WP_064147788.1\|4108062_4108365_-	hypothetical protein	NA	NA	NA	NA
WP_012967727.1\|4108374_4109472_-	hypothetical protein	F1C5E1	Cronobacter_phage	3.2e-151	73.6
WP_047680691.1\|4109483_4109915_-	hypothetical protein	F1C5E0	Cronobacter_phage	1.8e-41	60.1
WP_047680688.1\|4109918_4111304_-	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	2.7e-155	60.2
WP_047680685.1\|4111316_4111499_-	hypothetical protein	NA	NA	NA	NA
WP_159162401.1\|4111563_4112151_-	HNH endonuclease	A0A2I7S0H7	Vibrio_phage	1.5e-30	43.9
WP_073546894.1\|4112250_4113255_-\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	1.8e-108	66.0
WP_032419309.1\|4113181_4114651_-	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	1.2e-148	56.1
WP_032419310.1\|4114663_4116136_-\|terminase	terminase	A0A1W6JNY3	Morganella_phage	6.9e-250	82.9
WP_032419311.1\|4116135_4116738_-	hypothetical protein	A0A077KBY7	Edwardsiella_phage	3.1e-79	78.7
WP_032419312.1\|4117175_4117526_-	hypothetical protein	A0A0K2FIW3	Enterobacter_phage	7.6e-14	42.9
WP_032419505.1\|4117522_4118020_-	lysozyme	A0A1V0E5Q7	Salmonella_phage	4.8e-78	83.0
WP_012542609.1\|4117997_4118267_-\|holin	holin	K7P6H9	Enterobacteria_phage	2.8e-32	78.3
WP_032419313.1\|4118486_4119026_-	HNH endonuclease	A5PJ37	Escherichia_virus	2.1e-34	46.1
WP_032419314.1\|4119463_4120153_-	antiterminator	I6PDF8	Cronobacter_phage	6.7e-62	56.2
WP_009483890.1\|4120149_4120290_-	YlcG family protein	NA	NA	NA	NA
WP_032419315.1\|4120286_4120925_-	recombination protein NinG	H6WRY9	Salmonella_phage	7.0e-74	68.4
WP_032419316.1\|4120917_4121586_-	metallophosphoesterase	K7P6H8	Enterobacteria_phage	8.9e-104	77.8
WP_024264476.1\|4121582_4121750_-	NinE family protein	K7P7K0	Enterobacteria_phage	7.8e-09	62.5
WP_023283341.1\|4121755_4122352_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	3.6e-56	53.3
WP_032419317.1\|4122510_4122825_-	hypothetical protein	A0A220NQY7	Salmonella_phage	3.4e-05	35.6
WP_009308003.1\|4123929_4124106_-	hypothetical protein	NA	NA	NA	NA
WP_032419318.1\|4124105_4124435_-	hypothetical protein	NA	NA	NA	NA
WP_032419320.1\|4125122_4125347_-	hypothetical protein	H9C169	Pectobacterium_phage	8.3e-14	51.5
WP_032419321.1\|4125343_4125637_-	protein ren	O48423	Enterobacteria_phage	1.5e-26	66.7
WP_073546926.1\|4125636_4127052_-	AAA family ATPase	Q9MCT4	Escherichia_phage	6.3e-184	67.3
WP_073546927.1\|4127056_4127908_-	DNA replication protein	F1C5C3	Cronobacter_phage	5.9e-84	56.0
WP_032419324.1\|4127948_4128095_-	hypothetical protein	NA	NA	NA	NA
WP_001548453.1\|4128180_4128402_-	hypothetical protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_001548452.1\|4128481_4128673_-	hypothetical protein	A0A2R2Z333	Escherichia_phage	2.4e-09	55.4
WP_032419325.1\|4128777_4129488_+	helix-turn-helix domain-containing protein	K7P8B2	Enterobacteria_phage	3.7e-92	70.6
WP_004191592.1\|4129860_4130916_+	ParA family protein	H2BD62	Pseudomonas_phage	1.1e-140	68.8
WP_032419508.1\|4131104_4131308_-	hypothetical protein	A0A192Y6Q5	Salmonella_phage	4.5e-19	70.1
WP_004219883.1\|4131617_4131743_+	hypothetical protein	NA	NA	NA	NA
WP_008807814.1\|4131735_4131942_+	phage encoded cell division inhibitor protein	A0A0M4S6W3	Salmonella_phage	1.4e-31	94.1
WP_016529276.1\|4132022_4132307_+	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	8.6e-40	79.8
WP_014342891.1\|4132716_4133052_+	hypothetical protein	A0A0F7L7F5	uncultured_marine_virus	1.3e-10	34.3
WP_032419327.1\|4133048_4133672_+	YqaJ viral recombinase family protein	S0A2A9	Cellulophaga_phage	6.1e-46	48.6
WP_032419328.1\|4133668_4134097_+	hypothetical protein	M9NYX4	Enterobacteria_phage	5.8e-64	81.0
WP_032419329.1\|4134093_4134750_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.1e-113	87.5
WP_032419330.1\|4134746_4135883_+	DNA cytosine methyltransferase	Q858D4	Salmonella_phage	7.4e-159	73.1
WP_032419331.1\|4136098_4136371_+	hypothetical protein	Q716F1	Shigella_phage	3.7e-24	63.5
WP_032419332.1\|4136367_4137072_+	hypothetical protein	A0A1W6JP46	Morganella_phage	1.0e-25	34.3
WP_072032585.1\|4137287_4137623_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004143017.1\|4139094_4139961_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-30	34.8

DBSCAN-SWA_9

5115507 : 5158454

Shigella_phage(48.21%)

terminase,capsid,integrase,head,portal,plate,holin,protease,tail,tRNA

attL 5111016:5111032|attR 5147010:5147026

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5111016:5111032	attL	NA	NA	NA	NA
WP_002884942.1\|5115507_5116923_-	replicative DNA helicase	O80281	Escherichia_phage	5.7e-201	78.8
WP_002884941.1\|5117092_5118076_+	quinone oxidoreductase	NA	NA	NA	NA
WP_032418204.1\|5118258_5118501_-	envelope stress response protein PspG	NA	NA	NA	NA
WP_087835996.1\|5118640_5119678_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_001514812.1\|5119766_5120864_+\|integrase	site-specific integrase	S5MDN5	Escherichia_phage	1.4e-210	99.2
WP_001514811.1\|5120925_5121174_+	DinI family protein	K7PLW4	Enterobacteria_phage	3.1e-38	98.8
WP_073546902.1\|5121274_5121664_-	DNA polymerase V	K7P6F7	Enterobacteria_phage	2.6e-63	91.4
WP_136473586.1\|5121858_5123361_+	hypothetical protein	E5AGC8	Erwinia_phage	3.2e-69	34.6
WP_073546904.1\|5123397_5123802_-\|tail	tail fiber assembly protein	F1BUK2	Cronobacter_phage	1.1e-11	42.0
WP_073546905.1\|5123801_5124764_-	hypothetical protein	U5P0I1	Shigella_phage	8.7e-52	82.8
WP_052924723.1\|5124767_5125352_-	YmfQ family protein	O22003	Shigella_phage	1.8e-113	99.5
WP_073546906.1\|5125342_5126401_-\|plate	baseplate J/gp47 family protein	M1FQW3	Enterobacteria_phage	1.6e-200	98.9
WP_000424732.1\|5126387_5126813_-	phage GP46 family protein	U5P0R9	Shigella_phage	2.3e-81	100.0
WP_073546907.1\|5126812_5127361_-\|plate	phage baseplate assembly protein	U5P081	Shigella_phage	1.6e-95	97.3
WP_000999511.1\|5127360_5128440_-\|plate	baseplate protein	U5P0H6	Shigella_phage	2.6e-206	99.7
WP_000219913.1\|5128436_5129765_-	DNA circularization N-terminal domain-containing protein	Q8SBG8	Shigella_phage	8.4e-247	99.3
WP_001514801.1\|5129828_5130206_-	PH domain-containing protein	A5GZ63	Lactococcus_phage	2.3e-08	35.6
WP_073546908.1\|5130258_5132094_-\|tail	phage tail tape measure protein	S5FM63	Shigella_phage	1.2e-304	98.5
WP_000661054.1\|5132235_5132505_-\|tail	phage tail assembly protein	M1FPE4	Enterobacteria_phage	3.5e-43	100.0
WP_000090993.1\|5132504_5132861_-\|tail	phage tail tube protein	U5P076	Shigella_phage	1.2e-62	99.2
WP_073546909.1\|5132860_5134357_-\|tail	phage tail sheath subtilisin-like domain-containing protein	M1FN90	Enterobacteria_phage	8.5e-272	98.6
WP_000497751.1\|5134340_5134511_-	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	9.3e-26	100.0
WP_000779292.1\|5134519_5135080_-	hypothetical protein	M1FQV7	Enterobacteria_phage	1.0e-105	100.0
WP_000224835.1\|5135076_5135583_-	hypothetical protein	M1FPE2	Enterobacteria_phage	1.3e-83	92.9
WP_073546910.1\|5135557_5135968_-\|head	phage head closure protein	M1FJ87	Enterobacteria_phage	2.5e-72	97.1
WP_000927710.1\|5135964_5136288_-\|head,tail	phage gp6-like head-tail connector protein	S5FKK6	Shigella_phage	5.1e-57	100.0
WP_073546911.1\|5136290_5136491_-	hypothetical protein	S5FNU1	Shigella_phage	4.2e-25	93.9
WP_073546912.1\|5136540_5137746_-\|capsid	phage major capsid protein	U5P0G9	Shigella_phage	2.7e-223	99.3
WP_001193632.1\|5137760_5138411_-\|head,protease	HK97 family phage prohead protease	U5P4H2	Shigella_phage	1.6e-118	99.5
WP_032252663.1\|5138388_5139630_-\|portal	phage portal protein	U5P411	Shigella_phage	1.3e-241	99.3
WP_000605606.1\|5139629_5139812_-	hypothetical protein	S5FXQ9	Shigella_phage	1.7e-25	100.0
WP_021519685.1\|5139823_5141557_-\|terminase	terminase large subunit	U5P0Q5	Shigella_phage	0.0e+00	98.4
WP_073546913.1\|5141553_5142048_-\|terminase	phage terminase small subunit P27 family	U5P067	Shigella_phage	5.1e-88	99.4
WP_053287456.1\|5142173_5142524_-	HNH endonuclease	U5P4L6	Shigella_phage	8.3e-61	94.8
WP_052874970.1\|5142707_5143100_-	DUF2570 domain-containing protein	Q8SBD9	Shigella_phage	8.4e-54	86.9
WP_016244989.1\|5143083_5143560_-	glycoside hydrolase family protein	S5FV07	Shigella_phage	2.4e-87	97.5
WP_001120502.1\|5143563_5143899_-\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	5.2e-60	100.0
WP_000799659.1\|5143975_5145028_-	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	6.8e-207	99.1
WP_001547994.1\|5145634_5146387_-	antitermination protein	K7PGU5	Enterobacteria_phage	2.8e-138	100.0
WP_016236817.1\|5146400_5147390_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	6.2e-194	99.1
5147010:5147026	attR	NA	NA	NA	NA
WP_001061444.1\|5147397_5148207_-	KilA-N domain-containing protein	A0A291AWU7	Escherichia_phage	1.8e-151	100.0
WP_000767148.1\|5148226_5148616_-	RusA family crossover junction endodeoxyribonuclease	A0A0P0ZD39	Stx2-converting_phage	5.1e-67	96.9
WP_000210152.1\|5148612_5148939_-	LexA family transcriptional regulator	A0A0N7KZF7	Stx2-converting_phage	1.3e-52	98.1
WP_001433188.1\|5148935_5149589_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	5.6e-127	99.1
WP_110109894.1\|5149588_5150083_-	PerC family transcriptional regulator	A0A0P0ZCF0	Stx2-converting_phage	1.1e-85	98.1
WP_000104943.1\|5150079_5151021_-	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	4.9e-140	93.0
WP_001250269.1\|5151010_5151190_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_000514174.1\|5151365_5151950_-	hypothetical protein	A0A1C9II13	Salmonella_phage	5.5e-57	60.9
WP_001231956.1\|5151977_5152175_-	Cro/Cl family transcriptional regulator	K7PHB1	Enterobacterial_phage	1.1e-14	56.9
WP_000981537.1\|5152270_5152924_+	helix-turn-helix domain-containing protein	K7PLZ5	Enterobacterial_phage	5.7e-71	60.8
WP_073546915.1\|5153157_5153433_+	hypothetical protein	Q8SBF7	Shigella_phage	1.2e-46	96.7
WP_001323604.1\|5154015_5154396_+	hypothetical protein	U5P4J6	Shigella_phage	1.3e-62	100.0
WP_052870285.1\|5154461_5155286_+	DUF2303 family protein	U5P439	Shigella_phage	3.9e-149	99.3
WP_000008210.1\|5155413_5155950_+	5'-deoxynucleotidase	U5P0T3	Shigella_phage	9.7e-101	99.4
WP_001565177.1\|5155940_5156303_+	phage protein	U5P092	Shigella_phage	1.5e-65	97.5
WP_073546918.1\|5156302_5157112_+	hypothetical protein	Q8HAA7	Salmonella_phage	7.3e-76	61.4
WP_073546919.1\|5157111_5157684_+	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	4.0e-105	96.3
WP_001093909.1\|5157720_5157993_+	pyocin activator PrtN family protein	S5MQM5	Escherichia_phage	5.9e-38	86.7
WP_000549966.1\|5158019_5158454_-	type II toxin-antitoxin system YafO family toxin	A0A0S2SYH1	Pseudomonas_phage	5.2e-36	51.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP018449

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4625 : 38012

Morganella_phage(11.76%)

integrase,transposase

attL 14022:14040|attR 39145:39163

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011790968.1\|4625_5876_+\|transposase	IS4-like element IS10A family transposase	Q9E8P4	Bluetongue_virus	4.2e-171	71.4
WP_004187429.1\|6207_6465_+	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_020277900.1\|6433_6799_+	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_004187425.1\|6891_7326_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.2e-29	55.3
WP_019725070.1\|7313_8579_+	translesion error-prone DNA polymerase V subunit UmuC	A0A1W6JNT0	Morganella_phage	2.6e-112	50.4
WP_004187413.1\|8701_8911_-	hypothetical protein	NA	NA	NA	NA
WP_004187411.1\|8913_9132_-	hypothetical protein	NA	NA	NA	NA
WP_004206893.1\|9176_9860_-	hypothetical protein	NA	NA	NA	NA
WP_021526647.1\|9856_10129_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047731887.1\|10146_11421_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_015586034.1\|11948_12305_+	hypothetical protein	NA	NA	NA	NA
WP_015062853.1\|12282_12861_+	hypothetical protein	NA	NA	NA	NA
WP_004206898.1\|12862_13270_+	hypothetical protein	NA	NA	NA	NA
WP_004206899.1\|13422_13968_-	hypothetical protein	NA	NA	NA	NA
14022:14040	attL	NA	NA	NA	NA
WP_015586036.1\|14108_14570_+	hypothetical protein	NA	NA	NA	NA
WP_004187394.1\|14566_14815_+	helix-turn-helix transcriptional regulator	A0A248SLB9	Klebsiella_phage	1.6e-10	53.0
WP_004206901.1\|14807_15395_+	restriction endonuclease	NA	NA	NA	NA
WP_004187390.1\|15391_15877_+	hypothetical protein	NA	NA	NA	NA
WP_020316874.1\|15918_16122_+	hypothetical protein	NA	NA	NA	NA
WP_004187383.1\|16140_16881_+\|integrase	tyrosine-type recombinase/integrase	I3WFA4	Macacine_betaherpesvirus	9.5e-22	51.6
WP_011091047.1\|17121_18096_+	plasmid segregation protein ParM	A0A0A7NPX4	Enterobacteria_phage	6.1e-85	52.0
WP_004206904.1\|18098_18542_+	plasmid partitioning/stability family protein	NA	NA	NA	NA
WP_004187378.1\|18551_19115_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.2e-20	31.3
WP_004206905.1\|19493_19739_+	hypothetical protein	NA	NA	NA	NA
WP_004206906.1\|19731_20211_+	hypothetical protein	NA	NA	NA	NA
WP_004206907.1\|20239_20650_+	hypothetical protein	NA	NA	NA	NA
WP_052170007.1\|20798_21209_+	Mov34/MPN/PAD-1 family protein	NA	NA	NA	NA
WP_004187367.1\|21253_21520_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004187364.1\|22196_22376_+	hypothetical protein	NA	NA	NA	NA
WP_004206911.1\|22448_23309_+	DUF4942 domain-containing protein	I6RTT5	Marinomonas_phage	2.8e-17	29.9
WP_001617865.1\|23866_24742_-	class A extended-spectrum beta-lactamase CTX-M-14	A0A1B0VBP7	Salmonella_phage	6.1e-153	99.6
WP_001067855.1\|24975_25680_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_077270329.1\|25715_26258_+	recombinase family protein	E5FFF9	Burkholderia_phage	1.2e-29	46.7
WP_001082319.1\|26323_27127_+	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_015586041.1\|27354_28134_+	APH(3')-VI family aminoglycoside O-phosphotransferase	E4ZFP6	Streptococcus_phage	1.1e-31	35.1
WP_015586042.1\|28788_29490_-\|transposase	IS1-like element ISPa14 family transposase	A0A218MNG1	uncultured_virus	9.9e-37	55.0
WP_001082319.1\|29605_30409_+	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_001067855.1\|30826_31531_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_085950818.1\|32438_33559_-\|transposase	IS3-like element ISSen4 family transposase	S5WIU1	Leptospira_phage	1.7e-51	42.8
WP_073546935.1\|33644_33917_+	hypothetical protein	NA	NA	NA	NA
WP_014839983.1\|34235_34850_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	8.1e-35	47.4
WP_012477564.1\|35284_35875_+	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
WP_001493762.1\|36011_36584_+	recombinase family protein	M9Q1K0	Clostridium_phage	3.4e-19	39.4
WP_073546936.1\|36620_38012_+\|transposase	ISKra4-like element ISKpn19 family transposase	NA	NA	NA	NA
39145:39163	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018448

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP018447

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP018449

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection