CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP015369	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p2, complete sequence	0 crisprs	NA	0	0
NZ_CP015370	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p3, complete sequence	0 crisprs	NA	0	0
NZ_CP015367	Methylobacterium phyllosphaerae strain CBMB27 chromosome, complete genome	2 crisprs	WYL,DEDDh,RT,csa3	0	2
NZ_CP015368	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence	1 crisprs	c2c4_V-U1	1	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015367_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015367_1

1642157-1642282

Orphan

Consensus_repeat	Method
CGTCTTGGGCGTGTCCCCCTTGGG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP015367_1

>merge|NZ_CP015367|1|1642157-1642282|CRISPRCasFinder
CTTCTTGGCCGCTTCCGCCTTGCCGGCCTCGGTCTTGGCGTGATCCGGCTTGCCCCGCGTCTTGGGCGTGTCCCCCTTGGGTGTGTCCCCCTTGGGCGTCTCCCCCTTGGGCGTCTCCGTCTTGGG

>NZ_CP015367|1|1|1642157-1642282|CRISPRCasFinder
CTTCTTGGCCGCTTCCGCCTTGCC	GGCCTCGGTCTTGGCGTGATCCGGCTTGCCCCG
CGTCTTGGGCGTGTCCCCCTTGGG	TGTGTCCCCCTTGGGCGTCTC
CCCCTTGGGCGTCTCCGTCTTGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015367.1\|WP_043355943.1\|1636207_1636945_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|187594
NZ_CP015367.1\|WP_075380138.1\|1645721_1646075_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NZ_CP015367.1\|WP_043757120.1\|1641597_1641867_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_053608316.1\|1649070_1649445_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_075380136.1\|1640527_1641238_-\|DUF937-domain-containing-protein	unknown	unknown	gnl\|CDD\|226276
NZ_CP015367.1\|WP_043353541.1\|1647769_1647961_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_010685409.1\|1634540_1634951_-\|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl\|CDD\|234744
NZ_CP015367.1\|WP_043355937.1\|1632082_1634338_-\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_CP015367.1\|WP_043353533.1\|1645324_1645573_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_043355950.1\|1641312_1641513_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_043353544.1\|1648627_1648810_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_043382995.1\|1646717_1646969_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_043355941.1\|1635245_1636190_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_CP015367.1\|WP_075381894.1\|1639048_1640518_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379114
NZ_CP015367.1\|WP_043353537.1\|1646104_1646332_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_007559070.1\|1637277_1637517_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP015367.1\|WP_043383004.1\|1644216_1645245_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374260
NZ_CP015367.1\|WP_075380139.1\|1647020_1647263_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_075380135.1\|1637700_1638960_+\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|235987
NZ_CP015367.1\|WP_043353543.1\|1648073_1648373_-\|PilZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|377796

Protein	Function_ID	Function_description	E-value
NZ_CP015367.1\|WP_043355943.1\|1636207_1636945_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	6.1931e-124
NZ_CP015367.1\|WP_075381894.1\|1639048_1640518_+\|AAA-family-ATPase	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	5.57048e-10
NZ_CP015367.1\|WP_007559070.1\|1637277_1637517_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	1.28553e-33
NZ_CP015367.1\|WP_075380136.1\|1640527_1641238_-\|DUF937-domain-containing-protein	gnl\|CDD\|226276	COG3753, COG3753, Uncharacterized protein conserved in bacteria [Function unknown].	1.89758e-21
NZ_CP015367.1\|WP_043355941.1\|1635245_1636190_+\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	1.84926e-109
NZ_CP015367.1\|WP_075380138.1\|1645721_1646075_+\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.00116383
NZ_CP015367.1\|WP_043355937.1\|1632082_1634338_-\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_CP015367.1\|WP_043383004.1\|1644216_1645245_+\|hypothetical-protein	gnl\|CDD\|374260	pfam15967, Nucleoporin_FG2, Nucleoporin FG repeated region. Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.	0.00895709
NZ_CP015367.1\|WP_010685409.1\|1634540_1634951_-\|DNA-directed-RNA-polymerase-subunit-omega	gnl\|CDD\|234744	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed.	8.09302e-24
NZ_CP015367.1\|WP_075380135.1\|1637700_1638960_+\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|235987	PRK07314, PRK07314, beta-ketoacyl-ACP synthase II.	0
NZ_CP015367.1\|WP_043353543.1\|1648073_1648373_-\|PilZ-domain-containing-protein	gnl\|CDD\|377796	pfam07238, PilZ, PilZ domain. PilZ is a c-di-GMP binding domain which is found C terminal to pfam07317. Proteins which contain PilZ are known to interact with the flagellar switch-complex proteins FliG and FliM. This interaction results in a reduction of torque generation and induces CCW motor bias. This domain forms a beta barrel structure.	0.0022065

>NZ_CP015367.1|WP_043757120.1|1641597_1641867_-|hypothetical-protein
MTLLLAGFWPGLAGAAALGLVVGALVGWPDRLAASLGLCVVAGLVAAAALAGFVPGLPGLWLDGAGLILPVYCAACALGALGRRLVVRD
>NZ_CP015367.1|WP_043355950.1|1641312_1641513_-|hypothetical-protein
MPWTVESPHPAKRRAVRLPRPRAGAAATGLFLAGLILSAATVPLIEPADATTATHTTQAALTPPAR
>NZ_CP015367.1|WP_075380136.1|1640527_1641238_-|DUF937-domain-containing-protein
MGLLESAIGGVLGQVFGGQKQGAGGMSPLVKALLMLLLAKGASGGFGDIFGRGGRGEPGPEADRSGGAGPYGRDPGQHPADAGGRRPDDGGDIGGWDQYGGRRDGGPERPTDPSLPPGDFSDLSGMLDGPGDAPAPSRAAPEGQGDLGGLDGLVDRFRQGGLGDVIESWIGHGANRPVAPDQLARALGPDTVDTLQSQTGMDRDTLLAQLAQALPEVVHTLTPQGRVPGEAERRGW
>NZ_CP015367.1|WP_075381894.1|1639048_1640518_+|AAA-family-ATPase
MDIRPSDIAALTEKVKKRSFAHYLMEIKLANVRAFKGQKITLDFPVTAIIGTNVGGKSTILGAAALAYKAVKPGDFFPKSNVSDNSMADWRIEYELIDRSVDKSGTIARNARFVSAKWRREYLIDRDVVVVPIQRTVPASEQPRYKRFIGIYKEEGAVIEELSSDIRRRAGAVLGKNLKGYSVAKLKKEDSVYLMLGMQNENDYSQFHFGAGEASVIEMISSIEQAPDQALILIEEIENGLHPVATEKMTEYLIDVAKRKKSQVIFTTHSEYALKKLPPNAIWACIDGQAYQGKLSIDSLRAIKGQVEKQIAVFVEDDFAKDLLEEALRQIDSRLLDAAEVHKAGGYPFLIEVMQHHNKNPTVKIKAIAIVDGDQTEFEDETNSTYTLPGSTPELSVFNYINENVESLASVLQQRCLCPQVSQDKIVKIFEKIDLSTSDVHLYFSKIGQEMGFISELTVRKACISIYVENNKEHFEAIIQALRRRLEQG
>NZ_CP015367.1|WP_075380135.1|1637700_1638960_+|beta-ketoacyl-ACP-synthase-II
MRRVVVTGLGMVTPLGCGVEHTWSRLIAGDSGAGPIRGFESADLPCRIAAQVPFGDGTDGTFNPDLVMEVKEQRKVDPFIVYAMAAADEALKDAGWAPKSHEDQCATGVLIGSGIGGIGGIYDASVTLHEKGPRRISPFFIPGRIINLASGQVSIAHGLKGPNNAVVTACSTGAHAIGDASRLIALGDADVMVAGGAESPVNRLSIAGFSACRALTTGFNDTPEKASRPYDRDRDGFLMGEGAGIVVLEEYEHAKARGAKIYAEVVGYGLSGDAYHITSPSPDGDGAFRCMSAAVKRAGISPSEIGYINAHGTSTPMGDELELKAVERLLGDAAANATMSSTKSSVGHLLGAAGSVEAIFSILVLRDNVIPPTLNLDNPSVETKIDLVPFEAKRKRVDVVLSNSFGFGGTNASLVMRRV
>NZ_CP015367.1|WP_007559070.1|1637277_1637517_+|acyl-carrier-protein
MSDIAERVKKIVVEHLGVEPEKVVESANFIDDLGADSLDTVELVMAFEEEFNVEIPDDAAETIQTVGDAVKFLEKNSAA
>NZ_CP015367.1|WP_043355943.1|1636207_1636945_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MFDLTGRKALVTGATGGLGQAIARALHAQGATVALSGTRPAALEALAAELGERASPVAADLSDKDSVEGLVPAAEAAIGPLDILVNNAGITRDNLFMRMKDEEWEQVIAVNLTAAFRLSRAAVKGMMRRRSGRIVNIGSVVGSTGNPGQGNYAAAKAGLVGMTKALAAEVASRGITVNCIAPGFISSPMTDALNEKQREGILARVPAGRLGEGSEVAAACLYLASAEAAYVTGHTLHVNGGMAMY
>NZ_CP015367.1|WP_043355941.1|1635245_1636190_+|ACP-S-malonyltransferase
MRALIFPGQGSQAVGMARDLAEAFPQARAVLDEVDAALNQNLSRLMFEGPVEELTLTANAQPALMAASLAVLRVLEAERGLDLERDVACVAGHSLGEYAALAAAGSLTIADAAKLLRLRGEAMQEAVAPGAGAMAALIGTDLDSARSVAEAAADEAGGGAVCDVANDNGGGQVVLSGDRPAVERAIGIATGRGIKRAVMLNVSAPFHCRLMAPAAEAMARALAAVALKAPRVTLYANVAAAPVSDPEAIRTALVEQVTGTVRWRESVAAMAATGVDRFYELGAGKVLTGLVKRIAPQASATAVGTPADVAAFAL
>NZ_CP015367.1|WP_010685409.1|1634540_1634951_-|DNA-directed-RNA-polymerase-subunit-omega
MARVTVEDCIEKVENRFELVLLASHRARLLAAGAPLTIDRDRDKNPVVALREIGDETITADDLKEQLIHSMQKYVEVDEPEAETVPLLSSSPAAAAVAPQSSSDDAAVQFDRMSEEDLLRGLENLAPPVETDDEGE
>NZ_CP015367.1|WP_043355937.1|1632082_1634338_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MMRQYELVERVKRYNPAADEALLNRAYVYAMQAHGTQKRASGDPFFAHPLEVAAILTDLHLDDATIVAAVLHDTVEDTEATLEEIRRLFGPEIGALVDGLTKLKRLDLVSKQAAQGENFRKLLLAVAADVRVLLVKLADRLHNMRTLQHMREDKRHRIAQETLDIYAPLSGRMGMQELREELEDLAFRNLEPEVYATITQRLARLTAKSESVVETIAQVLTEKLAAQGITAEVSGRQKRPFSIWSKMERKSVAFEQLSDIFGFRVVVNTVQECYAALGIVHTSWPMVPGRYKDYISTPKQNDYRSIHTTVIGPKSQRVELQIRTCAMDDIAEYGIAAHAHYKEVGAELVKDPGRAEGSVHPRLAGESGAYQWLRRTIELLAEGDSPEEFLEHTKLELFQDQVFCFTPKGRLIALPRGATPIDFAYAVHTDVGNTAVGAKINGRMAPLLHELANGDEVEISRSDGASPPAAWESLVVTGKARAAIRRATRAAVRRQYAGLGRQILDRAFERAAKTFSEDKLRGALPRLARATTEDVFAAVGRGEMFSGDVVRAVYPDHRDERRPSPAQGAANGAGRLVRSADQTMRLTFQGADGKEGAEDRSDAIPIRGLAGDLPVTFAPNGGAVPGDRIVGILTPGVGVTVYPIQSAALAAFDNEPERWLDVRWDTEALGGERFPARLALKSINEPGVFAQIAQVIADHDGNIDNISMKRRTQDFTDITIDLSVWDLQHLNAIIAELRGKRPVNSVERVNG
>NZ_CP015367.1|WP_043383004.1|1644216_1645245_+|hypothetical-protein
MRSILAALLLPIAIPASAQSLSATATVPSSASPEPITPIANPGQLSLGGGTTTGPFPTVSAQTGGLVNAGQLSFGSAGGGGRIGASGGRAAGQSAGTAIGTSAAGSTGAGQLGTLGSAATGGAGVSGSSLRTGGTIGASGLRSGFGTASRSGLGASPGSTLSLTSGTIGLGGGSGLSLGLGSGGTTRTGQTTALTGAGSLNGLGNGTATGVGSVGTSGTLLPAAASAGLAGGTADAAAIGASGTTLSSVGPFGVFGLGTGATVSPGASISGAAGAGGVGTGGAGIVGASGLRADDPAQAARTLPSGGGAFGGAGIGGAAAAPVRTGDLCGDPLAEACLGGGF
>NZ_CP015367.1|WP_043353533.1|1645324_1645573_+|hypothetical-protein
MSVILGRVSFAAVLVLGVSGAALARDAGPKAQGAHGATGLHGIGFNEPKFRSHLQTGKNQPYTWPVSDRYRPVSQPYYGRAY
>NZ_CP015367.1|WP_075380138.1|1645721_1646075_+|hypothetical-protein
MHPLTRLVVAGPIVAPLVAASLPGCAGEFAPTAPVPGMALTQPDPGMASGAPAPVLPAQPAPVAAAPAPAPVQADPTGGRRRPPGLGSGFSSLEGRLPNQRTGLRHPHVVRDICIGC
>NZ_CP015367.1|WP_043353537.1|1646104_1646332_-|hypothetical-protein
MTPSDLDKRAELTIWPARATGRSAEGRPFATLREALAVALEAIASDDARPWIITEAGDILSPRWIQAHSRSRSLQ
>NZ_CP015367.1|WP_043382995.1|1646717_1646969_+|hypothetical-protein
MRTILILASAALTSAAFIGPAAADDHLHLTPPLYREQARPAQQIRAIHDLTTTPQPVAAPATVSRTVSALGRPMVQASVEASR
>NZ_CP015367.1|WP_075380139.1|1647020_1647263_-|hypothetical-protein
MMYGEVGRLADEGLRLSLQQAENAALLVMAMQYAWAELWLEGYRAAGAALSAERDQRARTRRLIRRGVSPAAAAQALHIV
>NZ_CP015367.1|WP_043353541.1|1647769_1647961_+|hypothetical-protein
MFTVKGIDPSGRVMTFACGTDEQAMEKTWELARRGFREITVADPKGKELSAAAFERSLNIDWD
>NZ_CP015367.1|WP_043353543.1|1648073_1648373_-|PilZ-domain-containing-protein
MFERRSAPRTILNETGSISVDEHRSLPCIVYDRSAGGVRIALPDTEIVPDRFILSIDASNEILVCQAIWRKADEIGATADVPETARSGGWTMLHELERA
>NZ_CP015367.1|WP_043353544.1|1648627_1648810_-|hypothetical-protein
MSRPLYLALALVLCGAAVTLFAFMRAPQSKEFAGWDVAFMSGIGAVALGFLTTLVEVVTG
>NZ_CP015367.1|WP_053608316.1|1649070_1649445_-|hypothetical-protein
MTRALLLPALLAAAVLPAAAAAAEDQKDATRTETIAGLVRIVGAQAGIVLYCRKFYTVDDAVSEGLSRTVRRALDVSLGHRQAQTVIAAEGRRVAEEIAAVGAEQWCADQREILNTDGVRVFID

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Crispr_ID: NZ_CP015367_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015367_2

3297319-3297414

Orphan

Consensus_repeat	Method
GTGCCGTCGTTGTCCGGATCGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015367_2

>merge|NZ_CP015367|2|3297319-3297414|CRISPRCasFinder
GTGCCGTCGTTGTCCGGATCGGCCATCTTGAAGCGCTCGCCGACCGCCGCGAGGTACTCCTTCTTGTCGAGGGTGCCGTCGCTGTCCGGATCGGCC

>NZ_CP015367|2|2|3297319-3297414|CRISPRCasFinder
GTGCCGTCGTTGTCCGGATCGGCC	ATCTTGAAGCGCTCGCCGACCGCCGCGAGGTACTCCTTCTTGTCGAGG
GTGCCGTCGCTGTCCGGATCGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015367.1\|WP_020092607.1\|3302304_3302667_-\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|234588
NZ_CP015367.1\|WP_043381150.1\|3296560_3296887_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_043349956.1\|3300925_3301162_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_075380770.1\|3289263_3290541_-\|HlyD-family-secretion-protein	unknown	unknown	gnl\|CDD\|224482
NZ_CP015367.1\|WP_075380772.1\|3291559_3294028_+\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_CP015367.1\|WP_075380771.1\|3290732_3291398_+\|HdeD-family-acid-resistance-protein	unknown	unknown	gnl\|CDD\|225786
NZ_CP015367.1\|WP_043381144.1\|3294998_3295268_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_075380774.1\|3298010_3299630_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173860
NZ_CP015367.1\|WP_075380769.1\|3287590_3289258_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP015367.1\|WP_043345682.1\|3294562_3294946_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015367.1\|WP_043349964.1\|3303003_3304566_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP015367.1\|WP_043381265.1\|3286149_3287382_+\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381617
NZ_CP015367.1\|WP_075380773.1\|3295680_3296487_+\|3-oxoadipate-enol-lactonase	unknown	unknown	gnl\|CDD\|131480
NZ_CP015367.1\|WP_075380776.1\|3305102_3305732_+\|ATPase	unknown	unknown	gnl\|CDD\|224117
NZ_CP015367.1\|WP_083683558.1\|3306042_3307176_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|239551
NZ_CP015367.1\|WP_075380775.1\|3299777_3300839_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293841
NZ_CP015367.1\|WP_043349959.1\|3301597_3302293_-\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|184351
NZ_CP015367.1\|WP_043381142.1\|3294032_3294461_-\|DUF1810-domain-containing-protein	unknown	unknown	gnl\|CDD\|378062
NZ_CP015367.1\|WP_043381159.1\|3304584_3304803_-\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|177518
NZ_CP015367.1\|WP_043349961.1\|3302674_3303007_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|181719

Protein	Function_ID	Function_description	E-value
NZ_CP015367.1\|WP_020092607.1\|3302304_3302667_-\|30S-ribosomal-protein-S16	gnl\|CDD\|234588	PRK00040, rpsP, 30S ribosomal protein S16; Reviewed.	1.55247e-40
NZ_CP015367.1\|WP_043349961.1\|3302674_3303007_-\|chorismate-mutase	gnl\|CDD\|181719	PRK09239, PRK09239, chorismate mutase; Provisional.	7.44693e-49
NZ_CP015367.1\|WP_075380772.1\|3291559_3294028_+\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP015367.1\|WP_075380771.1\|3290732_3291398_+\|HdeD-family-acid-resistance-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	1.00579e-22
NZ_CP015367.1\|WP_075380774.1\|3298010_3299630_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173860	cd08495, PBP2_NikA_DppA_OppA_like_8, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP015367.1\|WP_075380769.1\|3287590_3289258_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.86868e-107
NZ_CP015367.1\|WP_075380770.1\|3289263_3290541_-\|HlyD-family-secretion-protein	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	1.35522e-91
NZ_CP015367.1\|WP_043381142.1\|3294032_3294461_-\|DUF1810-domain-containing-protein	gnl\|CDD\|378062	pfam08837, DUF1810, Protein of unknown function (DUF1810). This is a family of uncharacterized proteins. The structure of one of the members in this family has been solved and it adopts a mainly alpha helical structure.	1.13992e-90
NZ_CP015367.1\|WP_043381265.1\|3286149_3287382_+\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381617	cd16896, LT_Slt70-like, uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	0.000143491
NZ_CP015367.1\|WP_075380773.1\|3295680_3296487_+\|3-oxoadipate-enol-lactonase	gnl\|CDD\|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	3.70364e-88
NZ_CP015367.1\|WP_075380776.1\|3305102_3305732_+\|ATPase	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.000150063
NZ_CP015367.1\|WP_083683558.1\|3306042_3307176_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|239551	cd03469, Rieske_RO_Alpha_N, Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The oxygenase component may contain alpha and beta subunits, with the beta subunit having a purely structural function. Some oxygenase components contain only an alpha subunit. The oxygenase alpha subunit has two domains, an N-terminal Rieske domain with an [2Fe-2S] cluster and a C-terminal catalytic domain with a mononuclear Fe(II) binding site. The Rieske [2Fe-2S] cluster accepts electrons from the reductase or ferredoxin component and transfers them to the mononuclear iron for catalysis. Reduced pyridine nucleotide is used as the initial source of two electrons for dioxygen activation.	3.74511e-32
NZ_CP015367.1\|WP_075380775.1\|3299777_3300839_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.10631e-75
NZ_CP015367.1\|WP_043349959.1\|3301597_3302293_-\|ribosome-maturation-factor-RimM	gnl\|CDD\|184351	PRK13828, rimM, 16S rRNA-processing protein RimM; Provisional.	8.66117e-51
NZ_CP015367.1\|WP_043381159.1\|3304584_3304803_-\|glutathione-S-transferase	gnl\|CDD\|177518	PHA03073, PHA03073, late transcription factor VLTF-2; Provisional.	0.00540194
NZ_CP015367.1\|WP_043349964.1\|3303003_3304566_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0

>NZ_CP015367.1|WP_043381150.1|3296560_3296887_-|hypothetical-protein
MRNDPPEDGANRFGLADLCAIAEAPHGDAARPSAEDAPALGAEGDGQAADAGAADLLGEIGDTLIVAYRLAVQDGDPTTVTLIRQALLHTGRRLARGMSPAEAGLSCH
>NZ_CP015367.1|WP_075380773.1|3295680_3296487_+|3-oxoadipate-enol-lactonase
MPQITVGGIGFRYLLEGPEGAPAVAFSNSLGATLEMWDALVPALTGRYRTLRYDTRGHGGSETRDQPITVTDLAGDLAGLLDALGIGRAHLVGLSLGGMTVQALASAEPERALSATLMATAAHMPSPQSWEERAATVRAQGLAAVVEATLGRWFTPGFAQRDPAAIQAIQAIRERFVACDPAGYAVCCGAIGCMDLRPALSAITAPTLVIAGRDDPSTPPAMAEEICASIAQAELLVLPHAAHLLAVERAEAVGGYLRAFLDRASRDT
>NZ_CP015367.1|WP_043381144.1|3294998_3295268_-|hypothetical-protein
MHDPSTGDAAIRPAEFWDTVAGLVTAKVEPVIGRGDRQRGPVIDYLRDLEALARRQCGSRETVQIIASGRRLLGDRSEIGPSDGPFTHA
>NZ_CP015367.1|WP_043345682.1|3294562_3294946_+|hypothetical-protein
MLGTLVAFMVANPAMSHALTATLETAGLAAALILLRSPRPEGIAALVVSTYYYGREAGQREHDLKHAGWDAVQAHLGAEFLYGWSLPNLQQWVAPTCAAWVVAGAIYLIRSRMARAAPLQPPRRGRF
>NZ_CP015367.1|WP_043381142.1|3294032_3294461_-|DUF1810-domain-containing-protein
MTDSHQLGRFVDAQEEIYECALAELRAGAKRSHWMWFVFPQIAGLGSSPMAQRYAIGSLAEAEAYAAHPVLGARLRACTAAVNAVDGRSAHAIFGSPDDLKFRSSMTLFDRAAPEEPLFAAALARYFDGVPDPRTLAKLQVA
>NZ_CP015367.1|WP_075380772.1|3291559_3294028_+|PBP1A-family-penicillin-binding-protein
MTPDAPERAPADGPNPPKPAPAAESPDPRLAAREAGRAARDLARHLRTMVTAAGLGLARGGRAISARAAARARTRSASVERPADTGVPEVDGRGVERRGARTILGRRHPALLAAGLVILLPVLALAVYLFAALVTLPPLGGAVVETGQRAITVEADDGRVFATRGSFRGQKLTAADLPPHLAQAIVAIEDRRFYSHWGIDLRGLARAAWRNLRGGGVREGGSTITQQYVRLTSLNQEKTLWRKVQEAFLALRVESTMSKDAILLGYLDSAYFGAGAYGADAAARRYFGKPAKALNLPESAMLAGLVRAPSQLAPTRNLGGAKERADVVLQAMVETGAITQAEADAARKQSVTLKSPPEAPPGTNYFLDMIAGDVKRLAGTDGDMTVRSTLNLDLQSLAEGVVARRLDKDGARRKVGQAAMVVLSKEGAILAMVGGRDYEDSQFNRAVQAKRQPGSLFKLLVYLTAYEKGYTPESVMVDRPVQIGDWDPENDDGRYRGPVPLRTAFALSINTVAAQLGQDVGIPAVIATARKLGIQSDLPNVPSLVLGSGAVSLLEMARAYGSVLSGRTPLQAYGIQAIRGAAPQPLYVRADAAPGQTLAQGPRTMMLDSLQAVVESGTGRAARVPGQIIGGKTGTSQDFRDAWFVGMTPDLVVGIWVGNDDDSPMNRMFGGEMPAGIFHDFIQRASEKLAKGKPRPSAERAEPPRAPAPAPTVEPAAVGEVRGVPEVIDTGTLNLRGRVVRLLGVVGERGHLARQLASYLRRREVVCSGLSDGATARCRIEGDDLAGLILAAGGARATEDAPPDLLGAEEQARAERVGLWGR
>NZ_CP015367.1|WP_075380771.1|3290732_3291398_+|HdeD-family-acid-resistance-protein
MTHSPSPTPQSPGSGSPTSPTGIPLVGVARLDAMSAALARNWWLVALRGVIAILFGVIAFVAPGAFVLSLVLFFAAYMLADGIIAIVGAVRAAQRHERWGFLLLEGVVDIVVGVAAALVPAAAVWAFVLLLAVWALVTGGLMIAAAFRLHLHYGRWWLVLGGVVSILFGLALLINPGMSALVLTLWIGSYTFAFGILLLILAFQLRSRHGAAAGPGTPLGR
>NZ_CP015367.1|WP_075380770.1|3289263_3290541_-|HlyD-family-secretion-protein
MFDDQRPSSEGEARPHPADGRPAVRERDVLDLGRAKPARDAGAAQETARKPGTEDAADDAEAQDGQSDDAAEDADDREDDARRPNVLRRHPFAFLLGGLAVVALCVGVFFYWLLYMHPYESTDDAFVDARSIAVQPKVGGYLVDVPVTDNQHVEAGQILFQIFQRDYQIALDQAKAQIEADEAGIKNIDAQIQAQYANIDVSKAQVATAEAALKFAQEDAARYKDLAERGSGSIQQSQSATSTLQQRQASLQSAQASVVAAQKQIGALQAQKASTQAQLARDRAQVEQAELNLGYTTVRAVQAGRVVRLTGGIGQLAQAGQSLAMFVPDDIWVTANFKETQITDMRPDQPVDIEIDAYPGRKIQGTVASVQPGSGTAFSLLPAQNATGNYVKVTQRIPVKIVVKNWPTDVSIGPGMSIVPTVTVR
>NZ_CP015367.1|WP_075380769.1|3287590_3289258_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MAGGTGAAASGRKPNTGKAQGGKARGGTASAKAPGGHNPWLIAGVVALATFMEVLDTTIANVALRYISGGLAVGPDEAAWVVTSYLVANAITLTASSFLAKRYGRKAFFMWSVALFTVSSILCGFAWSLESLLLFRVLQGLGGGGMAPLAQSILADSFPPEKRGQAFALYGVAIVVAPVIGPTLGGWLSDNASWHWCFLINGPVGVIALGLMYWLIEDSAAAKKERRALVRKGIRFDIVGFVLVALFLGSLEVILDEGQRKDWFGTSTLMNVSGVLMVVSFVAMIPWLLTKKNPAVDLRLIGNRQFGSCFLVMMFTGAILIATTQFIPQITQEYYGYTATLSGLVLGPGGIVTVVMMFLTGRVSAYVQPKWLIAAGMTIVALGMVDLTRLDGSTTFSFFAWSRVYIGIGLPMVFLSITSASYEGIRKDQTDQASALINVARNVGGSMGVSLAQNILAYRSQFHQSRLVESVNPTAPAYQETMRQATQYFSEHGYAGVEAQSQATAWIGSVLSTQVAYWAYIDVFWVLGLVAACAVPLALSLKSVKLGGGAPAGGH
>NZ_CP015367.1|WP_043381265.1|3286149_3287382_+|transglycosylase-SLT-domain-containing-protein
MGVFPEPARCADDVSRLVPPTLNGTGHIEDEAVAWLPRAGRGTGRRSLRRTGLGRISGTLALGLVAGLGLPQAAFAPAYFAPAAQAHDRIDTSPRAAQGLAQTASQPAAPAVAADEPVQNTWNGLPVPEQEPATTALIQEDLAALPRVTQEQGQDAVKFGERSVPRKVVDTIVKASDEAGVDPVYMMALADKESSFDTDAKAATSSAAGLFQFVARTWLEMIRDYGARYGLAEEAAAVKGRGAAITVTGSMRGRVLGLRNDPRVAALMAAELIKRDRERIEARVGRALTTTELYLAHFLGTASAGRFLSLSSEKPDEVAGREFRTAARANRSLFTAKTGGKRRSLTVAELHGRIDDMIDRRLTRYQGVAAVAEALDKGQSQNEIVSAEETAPVAGNRRVEVTEALPPDGV
>NZ_CP015367.1|WP_075380774.1|3298010_3299630_-|ABC-transporter-substrate-binding-protein
MDPIKPTRRSLMAGGVALAALGAAGRAGAQGAAPGTLTYGISMTDLPLTTGQPDRGAGGYQFTGLTLYDPLVAWELDVADRPGRMVPGLATAWEADPADPKVWTFHLREGVAFHDGSTFDADAVIWNFDKVLNKEAPHFDQRQAAQVRPRLPGVASYRKLDAKTVQVVTKTPDSLFPYQMLWFLISSPAQYEKVGKDWAKFAFDPSGTGPFRLGQLVPRVRLELLPNVGYWNPKRVPKLAKLTLTCVPEDLARVNALLSGSVDLIESPAPDAVPRLKAAGMRVVGNETPHVWNYHLSMLEGSPWRDLRLRKAANLAIDRAGVVELMGGLAQPAVGQVQESSPWFGKPSFKIKTDVDQARKLVEEAGYSVKNPVKATVLIPTGGTGQMLSLPINEFVQQSWAEVGIQVEFKTVELEVAYTAWRQGAADPSLKGVSAGNIAYVTSDPFYAILRFYDSRQIAPNGVNWSHYRNPEVDALCDKVKASLDVAEQNRLLARIHEIVVDDAVQVWVVHDTNPHALSPRVKNYIQAQHWFQDLATLA
>NZ_CP015367.1|WP_075380775.1|3299777_3300839_-|MBL-fold-metallo-hydrolase
MKRRSLLTVASAATVMTLGGVGYAAHRRGRNPYYRGPTSDHFDGLRFFLPEQATDKALSDVLRWQAKRQREPWPKSFPSPYPADRPPERVAGLRVVLIGHASYLVQVAGRNILIDPVFAKRASPVRFAGPKRVNPPGIAFADLPPIDAVLVTHNHYDHLDGPSLARIWQAHQPLIVAPLGNDTILRGYDDTMHVETRDWGQSVDLGDGLQVHLVPANHWSARGVNDRRMALWCAFVITSPRGVHYHVGDTGFGDGSLFSDIRARFGPPRLATLPIGAYEPRWFMHAQHVDPAEAVRAFALLGAEQALGHHWGTFQLTDEGVERPAEALTAALGGAGIAPGRFLALRPGQVWEV
>NZ_CP015367.1|WP_043349956.1|3300925_3301162_-|hypothetical-protein
MPRFFIDLHDGSQPIHDEVGFDLPDLPAARAKVTRIMSAIARDMLPDVERQDYVACVRDGVGKIVYRARLSLAAEMVE
>NZ_CP015367.1|WP_043349959.1|3301597_3302293_-|ribosome-maturation-factor-RimM
MARRPAGSTPRDGGRRGRTSSAIGKIAPDAATSPKAPAPKPAPLPVPPDPNLVLLGEFGRAHGLNGEVRLKSYTGDPRAIAGYGALLTADGRSLTLADVRLAPGSSPDMLIARVKGVSGRSAAEALNRVALFIPRDRLTAPEDDDEVYTADLIGATAVDEAGTLVGTIVAVPNYGGGDLLELRPPNGGATALLPFTKAFVPVLDMAQRRVTVAAPEDLFAPPGEKPADDPG
>NZ_CP015367.1|WP_020092607.1|3302304_3302667_-|30S-ribosomal-protein-S16
MALKIRLTRGGAKKRPYYRIVVADARAPRDGRFIDKVGAYDPMKAKDDPARIVLDNEKIQSWLAKGAQPTDRVLRFLDQAGLAKRPTRNNPQKAEPGEKAKERAAKRAEKAAAPAEDAAA
>NZ_CP015367.1|WP_043349961.1|3302674_3303007_-|chorismate-mutase
MSILSAQAVDPELARLRESIDNFDAALIHLLAERFRCTQRVGELKARKGIPPSDPDREARQVARLRKLAVEAKLDPDFAEKFLAFVVKEVIRHHQSIKADHESQIEQQRK
>NZ_CP015367.1|WP_043349964.1|3303003_3304566_-|signal-recognition-particle-protein
MFEGLSDRLSGILSGLTRRGALTEADVTAAMREVRRALLEADVALEVVRGFTDRVKEKAVGAVVLKSVTPGQMVVKIVNDELVAMLGTDAETVDLNAPAPVPILMVGLQGSGKTTTTAKIARRLSDREKRKVLLASLDTRRPAAMEQLAVLAKQVGVESLPIIAGQSAVQIAKRAMDAARLGGFDVVMLDTAGRTTVDEGLMAEAAEVKAATRPHEVLLVADALTGQDAVNTARAFDERLGVTGIVLTRMDGDSRGGAALSMRAVTGKPIKLVGVGEKVDALEEFHPARVANRILGMGDIVSLVEKAAETIDHEQALRTAEKMRKGKFDLEDLSMQLAQMEKMGGIGGLMGMLPGMGAIKKQVEGANLDEKMFKRQRAIISSMTPQERKNPDLLKNSRKKRIAAGSGVDVSEINKLLKMHRTMADMMKAMGQGKRGIGQALGSMFGLGGGGMGGGMPGLPPGMPEPTPEQIAQLEKQFGGKLPPMPPGLGGGGMPKLPGLPGLGGPKLPGLGGFMPGKKK
>NZ_CP015367.1|WP_043381159.1|3304584_3304803_-|glutathione-S-transferase
MTRDQEALNIEDAINETCPWSGKPISADSLTLYNGAVVGFCNPECRDKFASAVRGFEAALQARRVERAGLEQ
>NZ_CP015367.1|WP_075380776.1|3305102_3305732_+|ATPase
MSEPARSLSPTESGSFPATGPLRDWLAAMKAHAPTETHGDARPAEAQPEPKRVRGGEAAWSPRVVPAPEAPRAATEDPDIAELMAENLMLKAKLRVEAGRQDELQAILAEEIRTLREHIRDEIGSLEDLRAEQEEIRIEREEFRGERERFRIEREEMRAERDRALADRDVLRSERLTLVGERDALREERDLWRARTEALAQPLFQSQRR
>NZ_CP015367.1|WP_083683558.1|3306042_3307176_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MTGAPRSARTALNAPFANPQRPADESALDPDAMRQPLGNAWYCVGQARSLGTAGSRTGLRAVELNGEQIVLGRAPDGMPFALRDRCPHRGMALSKGRFDGDTLMCPFHGWRFGTDGRCRDVPTLSEHDAADFSRIQVQRFPIRESAGFLWVNPHIGPATGAVPEVPTLDFAPAGSLVVELVVEASFDLTTLSLVDPGHVAFVHDSWWFRPSKQLREKVKTFQPVPHGFVMTSHATTTSSPVYRLLGGVPEVEIEFRLPGVRLERIRAGEKRVANYTFATPLTPDRTLLTNALYWSMPALNLLKPVARPLMRQFLTQDQQVLQHAQDGLDRKPTMVLFGQGDLPSQWYFRLKREALESARDGRPFVNPLERRELRWRS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1210973 : 1219784

Streptococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053609825.1\|1210973_1212611_-	acyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	3.7e-34	27.9
WP_051044948.1\|1212690_1213305_-	PAS domain-containing protein	NA	NA	NA	NA
WP_043354541.1\|1213623_1214271_+	ParA family protein	W8ECJ6	Mycobacterium_phage	1.2e-12	34.6
WP_043354543.1\|1214254_1214593_+	hypothetical protein	NA	NA	NA	NA
WP_043761076.1\|1214874_1216206_+	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	1.6e-19	57.1
WP_043354561.1\|1216378_1217623_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.6e-50	36.2
WP_078947163.1\|1217633_1218356_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.2e-31	42.7
WP_043354545.1\|1218731_1219784_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.6e-06	38.7

DBSCAN-SWA_2

4719426 : 4736742

Paracoccus_phage(36.36%)

head,capsid,portal,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075381244.1\|4719426_4720620_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	1.8e-54	39.1
WP_043355122.1\|4720713_4721226_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	1.8e-24	45.9
WP_075381245.1\|4721252_4722545_+\|capsid	phage major capsid protein	A0A2D1GNH4	Pseudomonas_phage	3.5e-80	43.6
WP_043353382.1\|4722799_4723345_-	DNA starvation/stationary phase protection protein Dps	A0A222YYG6	Streptomyces_phage	4.8e-07	27.7
WP_078947095.1\|4723457_4724381_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_075381246.1\|4724507_4725278_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_075381247.1\|4725303_4725867_+	hypothetical protein	NA	NA	NA	NA
WP_043349544.1\|4725901_4726255_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_043349542.1\|4726251_4726680_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_043349538.1\|4726691_4727102_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_043387351.1\|4727107_4727440_+	gene transfer agent family protein	NA	NA	NA	NA
WP_075382066.1\|4727454_4727658_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_075381248.1\|4727667_4728234_+\|tail	phage tail tape measure protein	A0A1B2AP03	Escherichia_phage	3.5e-08	40.0
WP_075381249.1\|4728277_4728919_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	3.4e-44	48.8
WP_053609246.1\|4728933_4729809_+	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	6.9e-56	39.6
WP_075381250.1\|4729805_4730381_+	C40 family peptidase	F4YXU4	Roseobacter_phage	1.3e-29	48.6
WP_075381251.1\|4730368_4734277_+\|tail	glycoside hydrolase/phage tail family protein	A0A0B5A7K5	Paracoccus_phage	8.2e-181	35.8
WP_075381252.1\|4734295_4735546_+	DUF2793 domain-containing protein	A0A0K1LM54	Rhodobacter_phage	5.8e-40	45.8
WP_075382067.1\|4735585_4736119_-	GDSL family lipase	NA	NA	NA	NA
WP_075381253.1\|4736232_4736742_+	hypothetical protein	X2CYK8	Brucella_phage	5.7e-10	39.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP015368

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015368_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015368_1

126475-126581

TypeV-U1

Consensus_repeat	Method
CATCCCGGCCGCTGACGGGTAGCC	CRISPRCasFinder

1 spacers

c2c4_V-U1

The CRISPR arrays of NZ_CP015368_1

>merge|NZ_CP015368|1|126475-126581|CRISPRCasFinder
CATCCCGGCCGCTGACGGGTAGCCACACGATCCTGACAGCTGTCAGGATCCGGCTGTCGCCTTCGAACTCCCTGATCGACCTGCAACCCGGCCGCTGACGGGTAGCC

>NZ_CP015368|1|1|126475-126581|CRISPRCasFinder
CATCCCGGCCGCTGACGGGTAGCC	ACACGATCCTGACAGCTGTCAGGATCCGGCTGTCGCCTTCGAACTCCCTGATCGACCTG
CAACCCGGCCGCTGACGGGTAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015368.1\|WP_075382228.1\|129598_130606_-\|plasmid-partitioning-protein-RepB	unknown	unknown	gnl\|CDD\|274586
NZ_CP015368.1\|WP_075382209.1\|124736_124997_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_075382217.1\|135121_135409_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237792
NZ_CP015368.1\|WP_075382213.1\|128216_129422_-\|replication-initiation-protein-RepC	unknown	unknown	gnl\|CDD\|184349
NZ_CP015368.1\|WP_075382210.1\|125114_125630_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_159020422.1\|137812_138763_-\|hypothetical-protein	c2c4_V-U1	-	gnl\|CDD\|284650
NZ_CP015368.1\|WP_159020418.1\|125820_125961_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_075382208.1\|123218_124076_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_159020424.1\|138725_139493_-\|hypothetical-protein	c2c4_V-U1	-	unknown
NZ_CP015368.1\|WP_083683984.1\|142189_143884_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP015368.1\|WP_139231697.1\|121087_121417_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_139231699.1\|124226_124649_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_159020420.1\|136726_137452_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|237792
NZ_CP015368.1\|WP_139231698.1\|122263_123151_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|349751
NZ_CP015368.1\|WP_075382206.1\|121969_122236_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_083683977.1\|135471_136749_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP015368.1\|WP_139231696.1\|120692_121034_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015368.1\|WP_075382214.1\|130602_131811_-\|plasmid-partitioning-protein-RepA	unknown	unknown	gnl\|CDD\|274585
NZ_CP015368.1\|WP_075382215.1\|132182_132434_+\|thermonuclease-family-protein	unknown	unknown	gnl\|CDD\|366169
NZ_CP015368.1\|WP_075382203.1\|116522_120674_-\|relaxase-domain-containing-protein	unknown	unknown	gnl\|CDD\|274289

Protein	Function_ID	Function_description	E-value
NZ_CP015368.1\|WP_159020422.1\|137812_138763_-\|hypothetical-protein	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	5.34571e-05
NZ_CP015368.1\|WP_159020420.1\|136726_137452_-\|IS3-family-transposase	gnl\|CDD\|237792	PRK14702, PRK14702, insertion element IS2 transposase InsD; Provisional.	2.68123e-34
NZ_CP015368.1\|WP_075382217.1\|135121_135409_-\|hypothetical-protein	gnl\|CDD\|237792	PRK14702, PRK14702, insertion element IS2 transposase InsD; Provisional.	7.70249e-11
NZ_CP015368.1\|WP_075382213.1\|128216_129422_-\|replication-initiation-protein-RepC	gnl\|CDD\|184349	PRK13824, PRK13824, replication initiation protein RepC; Provisional.	0
NZ_CP015368.1\|WP_139231698.1\|122263_123151_+\|hypothetical-protein	gnl\|CDD\|349751	cd01983, SIMIBI, SIMIBI (signal recognition particle, MinD and BioD)-class NTPases. SIMIBI (after signal recognition particle, MinD, and BioD), consists of signal recognition particle (SRP) GTPases, the assemblage of MinD-like ATPases, which are involved in protein localization, chromosome partitioning, and membrane transport, and a group of metabolic enzymes with kinase or related phosphate transferase activity. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.	0.000333831
NZ_CP015368.1\|WP_075382228.1\|129598_130606_-\|plasmid-partitioning-protein-RepB	gnl\|CDD\|274586	TIGR03454, partition_RepB, plasmid partitioning protein RepB. Members of this family are the RepB protein involved in replicon partitioning. RepB is found, in general, as part of a repABC operon in plasmids and small chromosomes, separate from the main chromosome, in various bacteria. This model describes a rather narrow clade of proteins; it should be noted that additional homologs scoring below the trusted cutoff have very similar functions, although they may be named differently. [Mobile and extrachromosomal element functions, Plasmid functions].	3.42247e-121
NZ_CP015368.1\|WP_083683977.1\|135471_136749_+\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.31564e-24
NZ_CP015368.1\|WP_083683984.1\|142189_143884_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.47691e-19
NZ_CP015368.1\|WP_075382214.1\|130602_131811_-\|plasmid-partitioning-protein-RepA	gnl\|CDD\|274585	TIGR03453, partition_RepA, plasmid partitioning protein RepA. Members of this family are the RepA (or ParA) protein involved in replicon partitioning. All known examples occur in bacterial species with two or more replicons, on a plasmid or the smaller chromosome. Note that an apparent exception may be seen as a pseudomolecule from assembly of an incompletely sequenced genome. Members of this family belong to a larger family that also includes the enzyme cobyrinic acid a,c-diamide synthase, but assignment of that name to members of this family would be in error. [Mobile and extrachromosomal element functions, Plasmid functions].	0
NZ_CP015368.1\|WP_075382215.1\|132182_132434_+\|thermonuclease-family-protein	gnl\|CDD\|366169	pfam00565, SNase, Staphylococcal nuclease homolog. Present in all three domains of cellular life. Four copies in the transcriptional coactivator p100: these, however, appear to lack the active site residues of Staphylococcal nuclease. Positions 14 (Asp-21), 34 (Arg-35), 39 (Asp-40), 42 (Glu-43) and 110 (Arg-87) [SNase numbering in parentheses] are thought to be involved in substrate-binding and catalysis.	1.47421e-05
NZ_CP015368.1\|WP_075382203.1\|116522_120674_-\|relaxase-domain-containing-protein	gnl\|CDD\|274289	TIGR02768, conjugal_transfer_protein_TraA, Ti-type conjugative transfer relaxase TraA. This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.	2.91073e-84

>NZ_CP015368.1|WP_159020418.1|125820_125961_+|hypothetical-protein
MTFRDAYFECAGPMGFWVTTFVALVTGDLLFAAALSIGISLLLSGI
>NZ_CP015368.1|WP_075382210.1|125114_125630_+|hypothetical-protein
MTWIVRLRAHDNGRIVESATFQAPDAAMAAYRTLLGRKELVGEPLAAVFKPPQGVDPAGNVATLFSRFDMPVGYGRIAADDPRLDPFLTKDAGNEIALSACPDRPIVDWETDPRPFGECLKAWHAGIPGGRAAAARELRVPATTYKGWCDGRGSPTEGAIRRLMTYIDKDS
>NZ_CP015368.1|WP_075382209.1|124736_124997_+|hypothetical-protein
MTVNAHAGIAYPTADAAFLAMIADWTCAGGYNSSAEMAAWFAARTNASLADEFITDRAPDAEPLDRDDIIAAFAKLRAMSDPSDAL
>NZ_CP015368.1|WP_139231699.1|124226_124649_+|hypothetical-protein
MPDARWSDVDYDIKSAFRHLEAAARLWATDGFMPSPGLRSGNDADLDAYRAQMALRHTLQSAMTSLENGLRRVQEITGMDAFAGSPEMQRDLHEMQRTVHRIRRIDVTLAPEEIRTTVEAAERIRTGTLIKITKIRERLD
>NZ_CP015368.1|WP_075382208.1|123218_124076_+|hypothetical-protein
MSAELRSLDNGIAIKERWFAVGRTLYGLPDDEIERAYEVAKASGIVLDDALGITLFVGARIGRTVDDLVRLSTTLPPMLDKAGRNAAGAIRSAAKVATGKVVEAAVAQVEARHAEMSEAVGAQIASVARDMMREQLAAGQVRRAGLLASAVCIAVLLGLGVGYHLGSGYQATVTNQIAAYAARPDAAAWIRLMAANPDLDQRLAAYCNPRSSNFQRLASGVPTCNLPIYLEGPPLPTANVEGTGWMTRLEVTFERLPWLTTMFLGALLLAGIQWLNKKANGKARA
>NZ_CP015368.1|WP_139231698.1|122263_123151_+|hypothetical-protein
MARKPASSRAPQKLLLMVVGQKGGVGKTSFARSLLSHLRYDLGLAVAAYDGDGSVGGLVKVFGAKAEDGTIADIQDPATACKYYDIRSEKERDILLDSLDQGADIVLHDLAGGSLGSLTEIVDNGQQSLGRLCRAADEMGYRPVFVHVISNIEEALYSVGDYLDATAANRQPGPSSEMLADHVIVQNLFFGDPEDFIWLHGHEFTAKDGTRSERGGRIKSAILEPLGYPIVSFPRVPGGAFALAEFERVPLAQLNEVTRLRIAERMRLKAYLEQFADEVSPLRDFLKLAPVAKAA
>NZ_CP015368.1|WP_075382206.1|121969_122236_+|hypothetical-protein
MVHDLHEEIEAALRARRTFAQIAEHLTSQGVKVSQSSLQLYHRERRRELAGDPPPERARTSKSSASSPAPSAASAPNATSTARFKRPL
>NZ_CP015368.1|WP_139231697.1|121087_121417_-|hypothetical-protein
MARRKLVARIRVTIDDDLLAAAEAIARARKVDLGRILEEGIRVLINPVPSHQDYRELSDSVAAIAEFVGAQWALMPGAEGNPIIGNAGTYEDGRHEVAYDTRAALVEQA
>NZ_CP015368.1|WP_139231696.1|120692_121034_-|hypothetical-protein
MFEATPTAYMATGERCPGDLDARFTAPPHLQEVWSAGDDVLRARLRARHDAAVAIVVAAGIETGLIPSDTDILPSRFALESYLDLPTLDAKDEVAIRNAADEIGAAYLAALRV
>NZ_CP015368.1|WP_075382203.1|116522_120674_-|relaxase-domain-containing-protein
MFTCYRVTSIEYYEKRAAEAERDAVREPNPGDLQYYHDNGASERTGQWWASAGWSGQINGVVDRGEIDVGSLRDLAQGIDPETGAALIQQTKARRTVGYDCQMAAPKTVSVLWAVADERARGRIEQIHADAVRAALDWAQDQGLVITRRGSGGETHEAVREVAAATYLHTTSRAGDPQLHSHAVIVNICVRADGSTGTIDNIDLLNYQGAIGAYYRTALASGLREEFGWQPIRKERNFEIAGIGDNLVSMFSKRRMQIEEIAEARGYDTATSREAAQYANLASRGTKDDLAPLEDLERDWHRQIVDEGLDYAAIWDQAEEGARLFHPSRPSVLPHETLEQRQDRILLTAFETLLATSTVIEERHLLQTALEALQCEVDAPSATRAIERLSSSGLLVELGRHKDRPVYTTQSMIDLETGMIAAAVARKGEREFVQSERVEAALAARPTMSAEQMDAVRHALNTDGVAVVEGHAGSGKSFSSGAIAEAAREAGLEVHTIAPSWKATEVVRSDTDTTEEMARAVAKFLHEARSGDRHIGRNSVIILDEGGMVGLREMAEIARIAEEAGAKLVIAGDTRQLKPVAAGAPMELLRQHLGSSEITEIRRQREGWMRQASTDLATGKIEAAVDLYDKAGKVHWIAGRDATFAALARDWVEDVRQRPDESRIVLARRNADVNRLNELLRAEYAALGKLGDEAVTIKAVARGNGGAAVDLELRVGDRVFFGEGVNVRGHRINNADLATVVAVRDGRDPVLTVRLDKGAEVFARATEFAGWRPEGEAPVPRIQYALATSIHASQGATVDRTFVAESGGMGRESLYVAMTRHRQDARLYVETARIEDTLSSRKGVTVAASRTGASIPDAGDVDRLAATQNDIKRYAVATWSSPETKRNVTDFAKLDLKAPAAARVMLEHLRAGRHAILDRSTPSGPEIRLERQSQIPVSDRAAPAVPPAARVPMIRQAPPTAGRSAPEAPKSVPPRLQAAFERGRELARSGVVPPRQSLRISDDEKAKFLKTDLAEFAQAHGYRIDSSYSHRGQIGRDPVKIDGRSQLGWRLVAPNGDKLVIAPGSNHDMFFNWFRKDQQGWSGNILTFTNSELGLKKPGENLHYLRDKLGTGPKTSSAQPAFRERVEQESTPAIVDPTRIRRTWSKMEPGHNSRYLVEERGLRPELLAQFRATIRTEPESWTKSSNRGGVAFAHVDEEGRICGYERKGWGIQSEGKRSFSQFSANGSKTLALHGDTRAPAHVVIAENSIDGMSYVQHAGIKGNVLVVSTCGNPSAQALDLLARKASEFKSAKFEIARDADKGGEAWTGAIKAAIHLGAPDAKVAVRAPEDRYKDWNNQIRDLSRTDEVSRNKARLAEAPSAPPSSSDDKRAKPQQTERHVPKL
>NZ_CP015368.1|WP_075382213.1|128216_129422_-|replication-initiation-protein-RepC
MDHITTPFGRRTLSPGMVAAQVGARATEGKVAHKWKTFRAIAEAKEALGISDRTLVVLNALLTCLPETAMVAGNLVVFPSNKALSLRAHGMAETTLRRHLGALVQAGLVVRRDSPNGKRYALRGGEGVEQAYGLDLSPVLARAEEFDHLAAEAAAERRASALARGRVTIYRRDIAKMIEAGAAAGAVWQSYREAFAPLCFRLPRRVTAASLAPLLADLHSLASELGRALEGLLKTQNLDGNASQSGVHIENSKPEGIIVVEPAPEDQGPGRTVRDLPLALVKSACPDIVLYDRGSVATWRDLISTAGLVRGMLGVSASAWEDAKDTMGPENAAAVIAGILQRAEAIKSPGGYLRGLTEKSRAGQFSPWPMMLALLRQSSPGPKSGSPLSGSRGGGSSCDGS
>NZ_CP015368.1|WP_075382228.1|129598_130606_-|plasmid-partitioning-protein-RepB
MSRKALFTSLPPAAASDAPKPAVSAQPPSRTRPLMGSAGLIPDAQPVGAVGKSLSEMSERAKRAEEIERRLTAGQTIVELDPDLIDPSFVADRMEIAPEALKSLREKIEANGQLNPIMVRPHPEVAGRYQVAFGHRRLRAIKDIGREVRAVVREMSDEELVIAQGQENHEREDLSYIEKCVFASRLEQRGFSRATIMSALSVYKSDLSNMLSVAKIPEGVIEAIGPAPGTGRRGWIELAGLVDDHTVAINRAIRNADFASMDSDSRFKAVLTATKAAPDRASTEVWMSKGKPLAKVTLGGNKVALSIDRKKSPEFADFVLNRLRDLYQEFEATRS
>NZ_CP015368.1|WP_075382214.1|130602_131811_-|plasmid-partitioning-protein-RepA
MAGDTAKNTDSLPELKTLVQQHGASLSAQLLAHHRNTFPPEAEKTIRAFSPAETAKLLGIHESYLRQVATDAQAATIKNGRRSYSVQDIADLRRTLDHGPRSARRYLPHRSGSEHMQVITVMNFKGGSGKTTTSAHLAQYLALHGYRVLAIDLDPQASLSALFGHQPETHVGPGETLYGAIRYDDENRKPIAEIVRGTYIPDLHLIPGNLELMEFEHDTPRALQNRQAGDTLFFARIGQALGQVQNLYDVVVIDCPPQLGYLTLSALTAATAVLITVHPQMLDVMSMSQFLQMTGDLLDEVSRHGASTNYDWMRYLVTRFEPGDGPQNQMVAFLRSIFGEHVLIHPMLKSTAISDAGLTNQTIFEVERGQFTRSTYDRALESVNNVNAEIEAQIRKAWGRAA
>NZ_CP015368.1|WP_075382215.1|132182_132434_+|thermonuclease-family-protein
MEIDQPYGTPERDVMCVMVCGKLVDIDLHGRRYDGLVGLIRAGGTDMSEAMVAASAAWEYARYDSDQTMPGFRAAACQQGRGL
>NZ_CP015368.1|WP_075382217.1|135121_135409_-|hypothetical-protein
MTAQGGALRSAWLRAPPQNRRAIFPMCYGNYYVARDTRRFAHEPGLIPKTTPLESLLSNGMAEAFVRTLKRDYVCVSVLPDAESVLRQLPVWLAH
>NZ_CP015368.1|WP_083683977.1|135471_136749_+|IS110-family-transposase
MTRQQLTPPAGVLVAIDVAKARNEVLIEVPGSGRRRRLSVLNTRAEHDRLIALLSDLGQPVTCGFEATGNYHRPIAWRLLQAGFAVRLISSVGLARTREALHNGWDKNDPKDAQVMLHMIRIGASQVYHDPLAAGINDVQELSKTHDAVSKAKTEVLHRILTHYLPLYFPEVDRFRHNSRSDWFFAFLDRFPTPACITTLSKEAFIAAAWDVVGRKVAKAQLLGDIYETARSSIGLPVPPDAPAVSMFRLVIGEARGLIQQRDAIEATADALLTDSSDYKLLRRIPGIGPINALTILAEAGDLRRFGHHRQFLKFCGLDLATQQSGTFRGQTKLSKYGNARLRRTLWLAGQVAIRQRENGFRDKFERYIARDRHNADLRRKALTAITAKMARVVHAVIKTGADYRPFVEGPVPGGRTPLSRAVRA
>NZ_CP015368.1|WP_159020420.1|136726_137452_-|IS3-family-transposase
MLSADLPTYGYRRIHALLRRQAERDGRPAPNAKRIYRVMKVHGLLLQRHAGEPRRAVTRARWRWPRATPAGRLPVRSPTGWDALCSDRLEIAAENGERVWVACPLHCCDREAMSCVATMAGITGEDVRDLMVAAVEHRFGPVNQLPSLIEWLTDNVLRSEEGRLARQQVSVREHAPAVCLSSTSIQAAPADPDELSAIANTGSSRCTRHRGPHRPQHEMSIQAGDPSIIYRVVVLTPSRLC
>NZ_CP015368.1|WP_159020422.1|137812_138763_-|hypothetical-protein
MKEVIITRRRHGNSWRWAASFICTQQADRAVPEPTGAKRIAIDVGWRRVPDGLRVATVVISGQSPSFIVLPASMLESFSLIDELRSRLQASNRLGIEMLQSANLGSFAQPFQDLLRDFQSISEKRPVDLAKFCESDFFLLQARENVGMDLWAWRKGHKRLTEWLRNHHRKTVGHRNHFYQNKIIEALDQASEVIVNDVKVGEIAARRTSRSESPFVPNRVGHYRRIAAPSELIRALKLQAEKRKIAFNKLEAESPVRCPTCGSLSRKTRADALPQVCANCDSSFDQDVVACESLLSPAPTARTTRSVKARSAAATT
>NZ_CP015368.1|WP_159020424.1|138725_139493_-|hypothetical-protein
MTVTSTTPFGGIKTEVVIRKYGLLQPTNWAEDCESEMRLMDDLWNKLVYINDEYISKYISLMCQEKNFSEAKSQYDNSVAASAAVSDIASSKRRLAIIQKDVARRMADALRALETSRREEVKVARQESGLWWGNYNALVRSFERARSAAIRGGQTMHRRSGGGDGRITNTLQGGAAVEALFDGSLSQIMVRPISARAWLSEIRGERRRLQRTFLSATVFVRDGERRTVTWPMIMHRPIPAQLPREGGHHHASPSR
>NZ_CP015368.1|WP_083683984.1|142189_143884_-|ISL3-family-transposase
MAMARLHEVPGCRVLSIEDGHEASVVMHVRGCRCAGRCPVCGTLSTARHGSYQRHPADLPSLGRAVRLDLTVRRLRCLNPSCPRRTFCLPAPSLLAPHARRTRRLAKAQQRVGLAINARAGARLLANLSMPASASTLLRLMHAAPLPRVARARAIGVDDWAWRRGRAWGTLVVDLDHHRAIDLLPDRNSATFEAWLASHTDLEIVARDRSTGYARAAQAVVPRAQQVADRWHLLLNARQMLERWLVGAHARLRALPVPSGAAAPVPNYARDHAFPRSRTDQTAAQEAQRWRAVRHAQVQRRRAAGESIMEIARAIPLAPATVRRYASMERPPERGERRIGPSQLDPWLAYLERRRAEGCENGLQLLRELLERGYAGGSRQVHKWLQSRRTKVAITTPRRWRDAVPGMTAPGWAELPARREQLPGSKVLAWIMTVAPDRLSPADSALLARIVQDPDAATLHGLVQRFVGFVREAGRKGNGSSAHGIRRLAAFEAWIVEAKASGIRAAQTFASGLVVDAAAVRAALTMPWSNAQSEGQITKLKLIKRLMYGRAGFDLLRRRVLLAP

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015368_1	1.1\|126499\|59\|NZ_CP015368\|CRISPRCasFinder	126499-126557	59	NZ_JX627580	Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence	23497-23555	0	1.0
NZ_CP015368_1	1.1\|126499\|59\|NZ_CP015368\|CRISPRCasFinder	126499-126557	59	NZ_CP015368	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence	126499-126557	0	1.0
NZ_CP015368_1	1.1\|126499\|59\|NZ_CP015368\|CRISPRCasFinder	126499-126557	59	NZ_JX627580	Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence	23414-23472	1	0.983
NZ_CP015368_1	1.1\|126499\|59\|NZ_CP015368\|CRISPRCasFinder	126499-126557	59	NZ_JX627580	Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence	23580-23638	2	0.966

1. spacer 1.1|126499|59|NZ_CP015368|CRISPRCasFinder matches to NZ_JX627580 (Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence) position: , mismatch: 0, identity: 1.0

acacgatcctgacagctgtcaggatccggctgtcgccttcgaactccctgatcgacctg	CRISPR spacer
acacgatcctgacagctgtcaggatccggctgtcgccttcgaactccctgatcgacctg	Protospacer
***********************************************************

2. spacer 1.1|126499|59|NZ_CP015368|CRISPRCasFinder matches to NZ_CP015368 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence) position: , mismatch: 0, identity: 1.0

acacgatcctgacagctgtcaggatccggctgtcgccttcgaactccctgatcgacctg	CRISPR spacer
acacgatcctgacagctgtcaggatccggctgtcgccttcgaactccctgatcgacctg	Protospacer
***********************************************************

3. spacer 1.1|126499|59|NZ_CP015368|CRISPRCasFinder matches to NZ_JX627580 (Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence) position: , mismatch: 1, identity: 0.983

acacgatcctgacagctgtcaggatccggctgtcgccttcgaactccctgatcgacctg	CRISPR spacer
acacgatcctgacagctgtcaggatccggctgtcgccttcgagctccctgatcgacctg	Protospacer
******************************************.****************

4. spacer 1.1|126499|59|NZ_CP015368|CRISPRCasFinder matches to NZ_JX627580 (Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence) position: , mismatch: 2, identity: 0.966

acacgatcctgacagctgtcaggatccggctgtcgccttcgaactccctgatcgacctg	CRISPR spacer
gcacgatcctgacagctgtcaggatccggctgtcgccttcgagctccctgatcgacctg	Protospacer
.*****************************************.****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

16970 : 69743

Enterobacteria_phage(28.57%)

transposase,integrase

attL 8760:8775|attR 39047:39062

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
8760:8775	attL	NA	NA	NA	NA
WP_075382155.1\|16970_18032_+\|integrase	site-specific integrase	Q5QBN6	Enterobacteria_phage	1.2e-22	29.2
WP_083683988.1\|18704_20273_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_075382159.1\|24717_25503_-	DUF1837 domain-containing protein	NA	NA	NA	NA
WP_075382160.1\|25917_26400_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_075382161.1\|26384_26879_-	hypothetical protein	NA	NA	NA	NA
WP_075382162.1\|26972_31622_-	hypothetical protein	NA	NA	NA	NA
WP_075382163.1\|31923_33195_+	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_083683946.1\|33980_34286_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_075382166.1\|35220_35904_-	hypothetical protein	NA	NA	NA	NA
WP_083683990.1\|37461_38838_+	aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	A0A1V0SKB7	Klosneuvirus	2.5e-15	23.6
WP_107646921.1\|39019_40370_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	2.3e-10	27.1
39047:39062	attR	NA	NA	NA	NA
WP_075382169.1\|40948_42166_-	MFS transporter	NA	NA	NA	NA
WP_107352909.1\|42700_44095_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_083683951.1\|45641_55232_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.7e-147	26.6
WP_075382172.1\|55235_65573_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	5.0e-153	26.9
WP_170861907.1\|65637_65844_+	MbtH family NRPS accessory protein	NA	NA	NA	NA
WP_107646922.1\|66214_67175_+\|transposase	IS630 family transposase	A0A2H4UVU9	Bodo_saltans_virus	6.3e-10	24.1
WP_075382176.1\|67379_67757_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_075381867.1\|68504_69743_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	5.2e-41	32.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015367

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP015368

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection