CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP015611	Bacillus safensis strain U17-1 chromosome, complete genome	1 crisprs	cas3,WYL,DEDDh,DinG,csa3,RT	0	0	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015611_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015611_1

2767921-2768150

Orphan

Consensus_repeat	Method
GTTGATCTTTAGCAAGTTGTTCACTTCTTTCAACATCCACTTTCGGCATAACAT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP015611_1

>merge|NZ_CP015611|1|2767921-2768150|PILER-CR
ATCTTTAGCAAGCTGTTCACTTCTTTCAACATCCACTTTCGGCATGACATTCGAAGCACTTGTATTACTGCCGCCTTCCTCTTTCAGTTGATCTTTAGCAAGTTGTTCACTTCTTTCAACATCCACTTTCGGCATAACATTTGAAGCACTTGTATTACTGTCACCTTCCTCTTTCAGTTGATCTTTAGCAAGTTGTTCACTTCTTTCAACATCCACTTTCGACATAGCAT

>NZ_CP015611|1|1|2767921-2768150|PILER-CR
ATCTTTAGCAAGCTGTTCACTTCTTTCAACATCCACTTTCGGCATGACATTCGA	AGCACTTGTATTACTGCCGCCTTCCTCTTTCAGTTG
ATCTTTAGCAAGTTGTTCACTTCTTTCAACATCCACTTTCGGCATAACATTTGA	AGCACTTGTATTACTGTCACCTTCCTCTTTCAGTTG
ATCTTTAGCAAGTTGTTCACTTCTTTCAACATCCACTTTCGACATAGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015611.1\|WP_155761587.1\|2774761_2774920_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015611.1\|WP_075611201.1\|2775100_2775460_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015611.1\|WP_075611202.1\|2772915_2773419_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372239
NZ_CP015611.1\|WP_075611198.1\|2777031_2778261_-\|CpaF-family-protein	unknown	unknown	gnl\|CDD\|227297
NZ_CP015611.1\|WP_081378170.1\|2753482_2754658_-\|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl\|CDD\|273178
NZ_CP015611.1\|WP_075611200.1\|2775466_2776228_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015611.1\|WP_024425495.1\|2763972_2764395_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NZ_CP015611.1\|WP_155761586.1\|2774941_2775088_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015611.1\|WP_073979874.1\|2763140_2763980_-\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320685
NZ_CP015611.1\|WP_039177642.1\|2762673_2763084_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP015611.1\|WP_075611206.1\|2764674_2765823_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|376220
NZ_CP015611.1\|WP_073979873.1\|2762028_2762475_+\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|153097
NZ_CP015611.1\|WP_075611208.1\|2754684_2758389_-\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP015611.1\|WP_075612370.1\|2773697_2774669_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372237
NZ_CP015611.1\|WP_075612371.1\|2770511_2772968_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|315512
NZ_CP015611.1\|WP_041092938.1\|2773430_2773685_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015611.1\|WP_075611199.1\|2776232_2777045_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015611.1\|WP_075611207.1\|2758366_2761876_-\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP015611.1\|WP_081378171.1\|2765900_2766380_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015611.1\|WP_075611204.1\|2766409_2767387_-\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381612

Protein	Function_ID	Function_description	E-value
NZ_CP015611.1\|WP_075611202.1\|2772915_2773419_-\|conjugal-transfer-protein	gnl\|CDD\|372239	pfam12648, TcpE, TcpE family. This family of proteins includes TcpE a conjugative transposon membrane protein.This family of proteins is found in bacteria. Proteins in this family are typically between 122 and 168 amino acids in length.	6.36044e-21
NZ_CP015611.1\|WP_075611198.1\|2777031_2778261_-\|CpaF-family-protein	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	1.43223e-33
NZ_CP015611.1\|WP_081378170.1\|2753482_2754658_-\|exonuclease-SbcCD-subunit-D	gnl\|CDD\|273178	TIGR00619, Nuclease_SbcCD_subunit_D, exonuclease SbcD. All proteins in this family for which functions are known are double-stranded DNA exonuclease (as part of a complex with SbcC homologs). This complex functions in the initiation of recombination and recombinational repair and is particularly important in regulating the stability of DNA sections that can form secondary structures. This family is likely homologous to the MRE11 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	2.05512e-90
NZ_CP015611.1\|WP_024425495.1\|2763972_2764395_-\|transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	2.22249e-21
NZ_CP015611.1\|WP_073979874.1\|2763140_2763980_-\|M48-family-metalloprotease	gnl\|CDD\|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	7.50856e-49
NZ_CP015611.1\|WP_039177642.1\|2762673_2763084_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	1.21107e-17
NZ_CP015611.1\|WP_075611206.1\|2764674_2765823_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|376220	pfam18801, RapH_N, response regulator aspartate phosphatase H, N terminal. Rap proteins consist of a N-terminal 3-helix bundle and a tetratricopeptide domain. This entry represents the conserved region of the C-terminal bundle.	7.38214e-19
NZ_CP015611.1\|WP_073979873.1\|2762028_2762475_+\|ferritin-like-domain-containing-protein	gnl\|CDD\|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	4.09762e-32
NZ_CP015611.1\|WP_075611208.1\|2754684_2758389_-\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP015611.1\|WP_075612370.1\|2773697_2774669_-\|conjugal-transfer-protein	gnl\|CDD\|372237	pfam12642, TpcC, Conjugative transposon protein TcpC. This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.	6.38446e-45
NZ_CP015611.1\|WP_075612371.1\|2770511_2772968_-\|ATP-binding-protein	gnl\|CDD\|315512	pfam12846, AAA_10, AAA-like domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	2.73392e-137
NZ_CP015611.1\|WP_075611207.1\|2758366_2761876_-\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP015611.1\|WP_075611204.1\|2766409_2767387_-\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381612	cd16891, CwlT-like, CwlT-like N-terminal lysozyme domain and similar domains. CwlT is a bifunctional cell wall hydrolase containing an N-terminal lysozyme domain and a C-terminal NlpC/P60 endopeptidase domain (gamma-d-D-glutamyl-L-diamino acid endopeptidase), and has been implicated in the spread of transposons. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).	3.29203e-59

>NZ_CP015611.1|WP_075611204.1|2766409_2767387_-|transglycosylase-SLT-domain-containing-protein
MKKLLTAFFTFLPIVFFVGMLVVVVLIFGGSNQKEEIGGGDDEYVTNGIAPEIERLRHVFEKYARKEGVYDQLNIIMALTMQESGGRYLDIMQSSESIGLPPNSITSPEYSIQVGVKHFAAVFKKAGGDVRLTLQSYNYGGGFIDFVKKRGGKYTKALALEFSRFQALKLGWRSYGDPNYVDHVFRYLKGGGSVKPVNGAIEGYETVMNEALKYEGNPYQWAGSTPKTGFDCSGLVQWAYRKAGISLPRTAQEQYGATKKIAESQAVPGDLVFFTGTYQGKFITHVGIYVGDGRMYNSNDSGVQYSTLKKGYWREHLVSFGRIKN
>NZ_CP015611.1|WP_081378171.1|2765900_2766380_-|hypothetical-protein
MGGVILILGITSYYMTYNKLSAEKNQALKEKQKIENKMNHMTNSEAADMNQKFFEAFFQYEDADDREKAVRKLATDKAMSYAFPSKAPKKHSVTMQGDLLSLESYSKKVDEDRELYLNEAKIALTVNAVTTKQELIIQTELKKEKGGWIVDNLQVKGSN
>NZ_CP015611.1|WP_075611206.1|2764674_2765823_-|tetratricopeptide-repeat-protein
MRDLIPYDLVTTKLNDWYRAIKTENIDLAREIKQQVKNELDSMEENQDALLYFSLLEFRHSLLESHLNAKNPHDLEQTYLTLKKVERQENLTGMLEYYYYFFMGMYEFRRKELTTAISAYRKAEMMISEINDEIEQAEFYFKVSYVYYYMKQTYFSLNYANRALNIYEKYDDYLVQALRCRFVIGGNLIDESKFRQALHMFLEILDIAEKNKLAHIKGMAHINAAICYEELKQYSDVCEHLDLALNYLESHNNSFVTKALFNQTHVYLKRGMFLEAKYYYIKGLKYVDEFNDEEYKLKFMILTGVYYENDHSLILEAFDSLLEKNMYADVENLALEVAEYFSSNENFKLANDYFRMSIDVRRKIREEELIDEKNSGYIYNVD
>NZ_CP015611.1|WP_024425495.1|2763972_2764395_-|transcriptional-regulator
MKIPSFKYNEKGLNRFFGPLEGRIMEILYQGEDMPIKEVQQKLSDEKPINFNTVMTVLNRLTEKGIVEKKTKGRSSIYNPILTKEEFLNEQTKWITQGLMDDFGPLAVNHMVDAIESADPELLKVLEARLASKKEEQQNE
>NZ_CP015611.1|WP_073979874.1|2763140_2763980_-|M48-family-metalloprotease
MNKMKSSLLFLGGILIGLTIFYQMGYYVLSSFFGWNQAYNLIHVCQSVLEFYGFTPLKYFLDALVLYTLGFAIFYMTKQIKTYIQFKQNLMLAVDDQSTEYLSEKYTNDIIVFHCHEPLAFAMGMLQPKVYLSTSLTDMLDEEEIDAVVHHELHHKYSYDPLKAFTFSMLSKVIWYIPVLKHMRQSYSVFREVIADDYAIRQTGTELGVGQALLKLIKKRTQFQKQTKFAVSFGDRALNLRIQKILNPTYNIPFNVPIIPIVTSTILMVVLMIMLNLNY
>NZ_CP015611.1|WP_039177642.1|2762673_2763084_-|DoxX-family-protein
MKTNQEIGTLFVRVILGLIFFLHGLQAYQGGLGGTAAFFGQIGIPEFMAYIVKTIELVGGIALILGLGTRIFAALFVPIMAVAIMTVGFSKGFVGGYEFELSLLVMALYLTLSGSKMLSIDGLLKHQQQSNEAKFH
>NZ_CP015611.1|WP_073979873.1|2762028_2762475_+|ferritin-like-domain-containing-protein
MYYGYYEYSPYDMRQNTRIISDLEKAINGEYSAIQCYEKLAQRAKTPEAKKIIQEIRQDEVRHYQLFTKLYYSLTGKNHKPSVTEPCPDQFREGLLFAFKDEQKTVDFYLTVSDYVRDQGTKELMKRIAQDEQQHAVWFLYLLTHHVS
>NZ_CP015611.1|WP_075611207.1|2758366_2761876_-|helicase-exonuclease-AddAB-subunit-AddB
MEIQFLAGRSGSGKTTAILEEIKEQLRLDPLGPPIIFLVPDQMTFLMEYELAKTSEAGGMIRAKVFSFTRLAWSILQQTGGANRQFVTSTGIQMLLRKVIEEEKEKFKVFKKASDKPGFVEQIEKTMAEFKRYCMLPEDIEKISLSSMHSEYTEERRAGEKLHDLHVLYQQMEQHLQDEYVHSEDYLTLLTQQIPLSEEIKGAHIYIDGFYQFTPQQLLVIEQLLLHAEKITAAFTVDRSYHDKQPNELDLFRMTGKTYFQLYQLAKECGAAISEHILERNNRHLHTPDLAYLERQYEQRPVQPYQEVTPHLTVSKSASKRAEIEGVAREILHLVREEGLRLRDISVVARHVDDYKDTLKEVFRDYDIPFFIDGNESMQYHPLIELIRSSLDVIKGNWRYEAVFRCVKTEFLFPLELAKNKAREQADQLENYCIAYGVKGERWTNGSRFHYRRFQSLDEDFGQTDQEIEMEQMLNDVKEWIAPPLFQLQKRLKKAQKVKDMVAAVYVFLEEIQVPDKLEKARLEAEEAGRLAEAMQHGQVWDAVIQLMDEFVEMLGEEELSFPLFQQMMDTGLASLKFALIPPSLDQVFIGSMDLSRMYQVKCMFIIGVNDGVIPARPSDESVLSEDDREWLKRAGAELAETGKERLLDEQFLIYQALSSPSRHLYLSYPVSDEEGRSLLPSTLIKYCQELMPNHQHSLYVLDPEQLDDEEQLKFVANEHVSLSYTVSQLQQWLNQYPISGVWWSVYNYLIKSTHRDVSKNILSSLFFTNRAKRLKPNVTKELYGDHIQGSVSRMEKFNACAFSHFASHGLKLKDRQFYKLEAPDIGQLFHSALKHISDTLVEQKKDWKNLTKDDCVNYSRHAIEQLAPRLQKEILLSSNRHAYIKEKLQKILIRVSSILSEHARVSGFSPVGLELGFGGQGPLPPFTFQLKNGCTMELVGRIDRVDKAEGSKGLLLRIVDYKSSEKGLDLAEVYYGLALQMLTYLDLTITYSKEWLGVEATPAGILYFHIHDPLIQAPIPLAEDEIEQEIFKKFKMKGLLLEDVEAVKLMDQTLESGRSQVIQAGLKKDGSFRSDSAVLSEDHFHILTQHVRRTFEEAGERITNGEVAINPYKLKDQTPCRFCSFKSICQFDESIEDNEFRVLSSEKDDVVIDRIKKEGDQYANTKTE
>NZ_CP015611.1|WP_075611208.1|2754684_2758389_-|helicase-exonuclease-AddAB-subunit-AddA
MQIPKPNNSNWTDDQWEAIVSEGQDILVAAAAGSGKTAVLVERLIRKMTRPEDPVDVDRLLVVTFTNASAAEMKHRITEALEKELAKNPGSLHMRRQLSLMNRANISTLHSFCLQVLRTFYYEIDLDPGFRLADQTEGELLGDEVLDELFEDEYKAGKPSFFELVDRYTSDRHDLDLQWLVKRIYEFSRSHPSPEQWMRAFLSLYDVDAQTKVEQLPFYPYIKEDLSLVFRSCLELLERALALSKEPGGPAPRAENFIDDLEQVNELISHQDDFEKLYELLPNINFKRLKTCKGDEYDPVLLEKATDARNQAKKQLEKLKDEYFMRSPAQHLKSLAEMKPVVETLVELVIQFGQRFEKAKQEKSIVDFSDLEHYCLRILAEQDAEGNLIETEAAKYYQQQFEEVLVDEYQDTNLVQETILKLVSKGEHAADGNLFMVGDVKQSIYRFRLAEPMLFLNKYKQFTPDGKETGKRIDLNKNFRSRSDVLDSTNFLFKQLMGETVGEIEYDEQAELKLGASYPESKDTTTEMLLVHLDQQEAETDEEREELETVQLEARVIAKKIRELVEQPFQVYDAKQQMTRNLQYRDIVILLRSMPWAPQMMEELKKQGIPVYANLSSGYFEATEVSVILSLLKVIDNPYQDIPLAAVLRSPLVHLDENEMALIRTSDKKGTYYDAVKAFMSVTHSDHPTCKKLERFFRLLRKWRDFSMNHSVAELIWEVYRDTQYLDYVGGMPGGKQRQANLRALYDRSKQYEKAAFRGLFRFLRFIERMQERGDDLGAAKTFSETEDVVRMMTIHSSKGLEFPIVFTAGLGRNFNMMDLNQSYLLDKELGFGSKYIHPELRISYATLPLVAMKKKMRKELLSEELRVLYVALTRAKEKLFLVGSVKNQVKALSKWQNAATGEDWLLPDFERYQSKTYLDFIGPALIRHQAMSSILEETGDVVLSHPSAFTISFTQASDLLKEDMSLEKKQQDEVVQALMEGLPVEGYGNADEKVAERLSWRYPYLAASQVGTKQSVSEIKRMKEIQDEYSVPSSLRKARATLYDRPAFMKKKALTAAEQGTAMHTVMQHIALPSDEPYDDSRIQQLLDSLQQRDLLTNEQVQSIDQEGIAAFFSTSIGQKLLKADWVKREVSFSMVLPVKEVYSHIDAEGEPVLIQGMIDCLFETDGKLYLLDYKTDRVQGRYTGGPEAAVPILKKRYETQIALYAIAVERLTNRTLEEKILYFFDGNLEISL
>NZ_CP015611.1|WP_081378170.1|2753482_2754658_-|exonuclease-SbcCD-subunit-D
MRILHTADWHLGKTLEGRSRLDEQAQFLDELYQIVKDEHIDVIVMAGDAFDTVNPPARAEQLFYESLSALSDKGKRQVVVISGNHDNPDRLSAASPLTNDQGIHLIGYPTNDIIRVDVPSSSERLSIAALAYPSEARLNEVLAETFEEKLLRDHYNLKIQQAFQHLSTQFQADTVNIATSHIYVAGGSQSDSERPIEVGGAYTVAAESLPEAACYVALGHLHRPQTIKRAKTIARYSGSPLAYSFSESGYAKSVTIVEAKPNEKASWKEVLLSSGKPLVKWKATEGLSQVHEWLDEKRDLQAWIDLEIHLTDQLSIEEIHQLRKQHSGFVHIRPKFKELQQLEEQKQVEKLSIEERFVKFYERQTGGGLPDEKTVKLFLELANEMQEEEAT
>NZ_CP015611.1|WP_075612371.1|2770511_2772968_-|ATP-binding-protein
MILTRTGDVWAYYRIKSSSIPSRNEHEIEEYKDRWTSFYEEITDYEDFHLMMYPSRFDLEGRLSVLKKDIHEDSVEVASYYMQETVNVMKQRLGRLTKPDFIIGIKLNKSLLSLDADIKDNVVSMFNTVTDTVVNMLGWEQDVSSPFFEQYKEIEDDLASTVTSVFGERLREAELKYINRYHFIRGLYHDVEEESQNGDIHSITNTVIDPTIPGSLKLVSDQDEGHISMIVVDEFLDNMANSNLFYEVQSLPFPVEVEVKAKVESKSMTKTSLNIKHQQLREEQNEKYSVGDESDQSTMTSAFLVKDLQNKIKKEEVSLINWLAVVIVDGRTKKECAEKARLVVRHLKGAGIKCRIPIADQLSLFYKMLPAEKLDLMDKNWVQKTTQNGLAECMLGVDSFVGSKIGFFLGWGDRFDKHTDLESAIRSSRDFVLYHPFLANQQIKGSKTRSPHCLITGNTGNGKSFLAKVLYTYISFMDIKSLYIDPKKEMRKWIKKVINNPQTRKNFPLYIDHLEKYHFITLDHEQEENWGALDPISFMPPTKAKDLLEVIFEQVYDFKGKDNVSTAFLRAITKVLEMKEQGEQVGSLHVIYELQRHEEEAVKKAGDYLYEVVQDSIMKLLVHDGSNPSLSLKERITILEVENMDLPDFGERIENFTKSQLKSSAVMFALGKFCELFGMNAEEKTAEFIDEAWIFTASPQGRKVERQMRRIGRSYNNAEFFISQSTKDALHEDDTGNFGVAFAFDEPNEREEVLRWMNLEPSEENKKMLESMFQGQCLFKDIYGRTAKISIECLFDEWMGAFETINKSEVAYAEEMYL
>NZ_CP015611.1|WP_075611202.1|2772915_2773419_-|conjugal-transfer-protein
MSRFVFNYRKAMREPKKIQRITENYSLPFSIELIPMINYFIFVAISFGFFIGVRRIFPHAFENTFVIVIFGIPLGLTILITKIKPEGKNIYLYFWGLLKYLIMIKLPKKRFCNDKVMGFSNDQEIKFKSLVKVVRKNGESENTNENPVKQHDLDENGRRLGVLSNKE
>NZ_CP015611.1|WP_041092938.1|2773430_2773685_-|hypothetical-protein
MEFLDFLVLGAKTDLPTLGGVQSWGKQVVTQFIFIVAMLLISKHLMKLSVGKMVGVLITTSAGVWVVQNWSTVTGWVGALLKKL
>NZ_CP015611.1|WP_075612370.1|2773697_2774669_-|conjugal-transfer-protein
MAIRNNSLLSAFKKKLKSVKKPEKKPKSIPKDRSKMIAIGIWSMIATLIFFAFISVLLSINTRSVVNDIERNQEQNSKQREEVSTVAGERFLSGFITEYINVKNENDAIEKRHNRLMTYLVKESDELEQETLFDISGAQGDRVLNNYTLYNVKQEKEETLFQYEIEYSNIVRVKKKEHEIKKQALLNIPVKNKGDQFAVSGTPYISEIYDLKGSIEIDKEDREEYDGDQTAVIKEFVNTFFRKYAEESKDDMSYVMKTPETLNGHLVFGDVENVRIYKSGDGFEISSVVIFKEKETSIPVKERFTLFVTKNTGQYYVNKLKHQ
>NZ_CP015611.1|WP_155761587.1|2774761_2774920_-|hypothetical-protein
MAVPENVDRFSWGTLAAVIAGAVGMALLVGLTDFVPWLMDFIQTSIKGLAKK
>NZ_CP015611.1|WP_155761586.1|2774941_2775088_-|hypothetical-protein
MEHNIFRLGMMGILMLTLGSVLMELNDGFPNVLNNIENYIEHVTRDMH
>NZ_CP015611.1|WP_075611201.1|2775100_2775460_-|hypothetical-protein
MIEGSVMTLFKVYIFCFSLVLSVDTAASLIRMNQLEDFKQYTNYQIERNGGLTKDALQAIEEKNQNSFGGSFQIESGSLNKKYPYGTEITYKVSTNYQYLITGYKTVFTVKGGALSLVR
>NZ_CP015611.1|WP_075611200.1|2775466_2776228_-|hypothetical-protein
MKNEKVKQTVPQKTVFSFWEKIGESNLREMLLYLNPELSFEGFQKKRFFKAASIFLASLPLIAFKPIVAVIALALACFIYHMDYRKIKGWYEVEKFQRELVFFKFSREVYIYLLENMSTVYQAFERLSSRVDEGLLKESLKKLLISMNESPNDVQPFIDFANDTSGSDSARLFMLTLYEYQQNSKDDSIIYELGKMTNEQLFMTVDDIVEYKLRKFGTFPTKIAMPVMIVMISFFITLLIDGVKSIQFINGGG
>NZ_CP015611.1|WP_075611199.1|2776232_2777045_-|hypothetical-protein
MKFRKKKLYSLDEIRAMSIAFGQPLQKREYAKFILTPFICFAGFAYLLFHYWWMALICGLIGGSYGWFYQLRRKVKNDYEKEAFQERNNFLNNMTQLLTNDDMPLVEAFSTCTIYAEGELKQKLIDLEITLIDSDEKEVVEAFKSLRRAYKNDVQFDQYIEQLGIMFVEGRTSILTLKDTKDYHNKVLLKQQRFIEDKQQHKKDFRTMILYSIGFIVGIMLSFTLKKYVDIYAHALVGMIANTVYLSIIFYFYHQFNQRYFDDAVTEVKI
>NZ_CP015611.1|WP_075611198.1|2777031_2778261_-|CpaF-family-protein
MITEIEEQKKLLEDVRKHLKLNHPSELLKAFVDLEARGKVNEVVKKDFPHLSNEELKFVMAEVVGLGVIEKIIDEYEGVTDISYNGTHLDVITNQGKFRYGEIEESYIIKIIQKFANACRKEFTRKNPILDASFSNLRLNAVHKDIAQYGTTMALRVVRPKLALHQENFKSFAPDYIFDLLKAIVASKSNVTIAGETGTGKTELQKLLLSFVEYKDHIVMIEDTPESHAKILFPDKDIKSWITNPSINIEMLVKAGLRNNPAWQVVSETRGREAYEMMQGILTGHRLITTLHAVNARAIPSRLINMMKMGHDIDETSMKEDIFRYLNFGIHIEKIEDEEGHMQRYLKEIVEFLPNGEVLTVFRCDLTNNGFEFVQGKVSSIFMNRMMEKRVDIQLQSEIIDGWGVHEIS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

69099 : 78019

Clostridium_phage(16.67%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041085256.1\|69099_70812_-	DNA polymerase III subunit gamma/tau	D9ZNI9	Clostridium_phage	3.4e-54	34.3
WP_041085258.1\|71481_71958_-	nucleoside deaminase	NA	NA	NA	NA
WP_041085260.1\|72037_72592_+	cysteine hydrolase	NA	NA	NA	NA
WP_041085262.1\|72637_73939_+	LysM peptidoglycan-binding domain-containing protein	A0A2P1CIG4	Microbacterium_phage	1.0e-07	34.8
WP_039175853.1\|74024_74648_+	AAA family ATPase	S5MMC6	Bacillus_phage	4.1e-18	28.9
WP_039175851.1\|74644_75304_+	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	1.1e-21	33.2
WP_041085267.1\|75812_76643_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.7e-09	57.1
WP_039175845.1\|76744_78019_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.4e-97	50.8

DBSCAN-SWA_2

360000 : 412645

Tupanvirus(25.0%)

holin,lysis,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039182414.1\|360000_360681_-\|lysis	CidB/LrgB family autolysis modulator	NA	NA	NA	NA
WP_081378132.1\|360674_361058_-\|holin	CidA/LrgA family holin-like protein	NA	NA	NA	NA
WP_075612125.1\|361222_362110_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_075612124.1\|362127_362952_+	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_075612123.1\|362938_363607_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_041087666.1\|363740_364115_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_041087667.1\|364140_364479_-	DUF4288 domain-containing protein	NA	NA	NA	NA
WP_024423846.1\|364799_366341_-	cation acetate symporter	NA	NA	NA	NA
WP_075612122.1\|366337_366652_-	DUF485 domain-containing protein	NA	NA	NA	NA
WP_075612121.1\|366759_367428_-	streptomycin biosynthesis protein StrF	NA	NA	NA	NA
WP_075612120.1\|367420_368110_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_008345506.1\|368410_368551_-	DNA-binding anti-repressor SinI	NA	NA	NA	NA
WP_080652923.1\|368960_369392_+	GtrA family protein	NA	NA	NA	NA
WP_024423842.1\|369419_369677_+	hypothetical protein	NA	NA	NA	NA
WP_007497828.1\|369711_370557_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_081378133.1\|370732_371920_+	galactokinase	NA	NA	NA	NA
WP_075612119.1\|371919_372912_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	8.2e-53	38.3
WP_075612118.1\|372948_374460_+	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_075612117.1\|374472_375555_+	M24 family metallopeptidase	NA	NA	NA	NA
WP_087976235.1\|376072_377029_+	cytochrome aa3 quinol oxidase subunit II	NA	NA	NA	NA
WP_007497822.1\|377056_379015_+	cytochrome aa3 quinol oxidase subunit I	NA	NA	NA	NA
WP_039182371.1\|379014_379632_+	cytochrome aa3 quinol oxidase subunit III	NA	NA	NA	NA
WP_007497818.1\|379633_380014_+	cytochrome aa3 quinol oxidase subunit IV	NA	NA	NA	NA
WP_008345491.1\|380091_380355_-	hypothetical protein	NA	NA	NA	NA
WP_075612116.1\|380831_382043_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_075612115.1\|382154_382904_+	oxygen-insensitive NADPH nitroreductase	NA	NA	NA	NA
WP_081378199.1\|382961_383963_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_075612113.1\|383974_384202_-	hypothetical protein	NA	NA	NA	NA
WP_075612112.1\|384283_386710_-	S8 family serine peptidase	A0A217EQY2	Bacillus_phage	1.5e-20	37.6
WP_075612111.1\|387210_387489_+	hypothetical protein	NA	NA	NA	NA
WP_075612110.1\|387541_388375_+	PRD domain-containing protein	NA	NA	NA	NA
WP_039182351.1\|388631_390020_+	PTS sucrose transporter subunit IIBC	NA	NA	NA	NA
WP_075612109.1\|390039_391497_+	sucrose-6-phosphate hydrolase	NA	NA	NA	NA
WP_075612108.1\|392229_393318_+	amidohydrolase family protein	NA	NA	NA	NA
WP_075612107.1\|393482_394823_+	MFS transporter	NA	NA	NA	NA
WP_041087697.1\|395040_395295_+	hypothetical protein	NA	NA	NA	NA
WP_073978830.1\|395449_396523_+	peptidase	NA	NA	NA	NA
WP_024426411.1\|396568_397378_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_041087704.1\|397503_397818_-	general stress protein 17m	NA	NA	NA	NA
WP_041087706.1\|397946_398774_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_039182328.1\|398770_399451_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	9.2e-48	44.3
WP_075612106.1\|399484_400843_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_039182322.1\|401013_401346_+	YwdI family protein	NA	NA	NA	NA
WP_041087711.1\|401379_402687_+	purine permease	NA	NA	NA	NA
WP_025093833.1\|402757_403129_+	DUF423 domain-containing protein	NA	NA	NA	NA
WP_039182316.1\|403170_403788_-	cupin domain-containing protein	NA	NA	NA	NA
WP_041087716.1\|403917_404460_-\|coat	spore coat protein GerQ	NA	NA	NA	NA
WP_075612105.1\|404652_405327_-	hypothetical protein	NA	NA	NA	NA
WP_155761606.1\|405493_406273_+	glycosyltransferase	NA	NA	NA	NA
WP_075612104.1\|406279_407692_+\|coat	spore coat protein	NA	NA	NA	NA
WP_075612103.1\|407713_408892_+	DegT/DnrJ/EryC1/StrS family aminotransferase	NA	NA	NA	NA
WP_041087724.1\|408888_409764_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_075612102.1\|409765_410890_+\|coat	spore coat protein	A0A1B1IVE2	uncultured_Mediterranean_phage	1.4e-21	29.5
WP_075612101.1\|410879_411620_+	NTP transferase domain-containing protein	NA	NA	NA	NA
WP_075612100.1\|411616_412645_+\|coat	spore coat protein	NA	NA	NA	NA

DBSCAN-SWA_3

719593 : 729524

Bacillus_phage(42.86%)

integrase

attL 723323:723336|attR 730021:730034

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075611966.1\|719593_721216_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	7.3e-43	27.6
WP_075611965.1\|721243_721585_-	hypothetical protein	NA	NA	NA	NA
WP_041088147.1\|721722_722301_+	TIGR00730 family Rossman fold protein	A0A1V0S9E9	Catovirus	2.4e-12	29.2
WP_024427684.1\|722361_722958_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	5.8e-54	54.4
723323:723336	attL	NA	NA	NA	NA
WP_075611964.1\|723418_724555_-\|integrase	site-specific integrase	Q5YAA6	Bacillus_phage	1.4e-112	55.7
WP_075611963.1\|724777_725866_+	helix-turn-helix transcriptional regulator	A0A288WG12	Bacillus_phage	6.3e-14	25.4
WP_075611962.1\|726289_726682_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_075611961.1\|726846_727053_+	helix-turn-helix transcriptional regulator	D6R414	Bacillus_phage	5.9e-06	39.1
WP_075611960.1\|727079_727412_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_075611959.1\|727417_727660_+	hypothetical protein	NA	NA	NA	NA
WP_075611958.1\|727993_728401_+	hypothetical protein	NA	NA	NA	NA
WP_075611957.1\|728471_729524_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.1e-60	37.1
730021:730034	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1029774 : 1059005

Bacillus_phage(28.57%)

terminase,tail,plate,capsid,holin,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075611834.1\|1029774_1030140_-	helix-turn-helix transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	2.6e-17	43.7
WP_075611833.1\|1030299_1030563_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_075611832.1\|1030689_1030878_+	hypothetical protein	NA	NA	NA	NA
WP_041088550.1\|1030980_1031382_+	hypothetical protein	NA	NA	NA	NA
WP_039181014.1\|1031378_1031585_+	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	2.6e-14	68.5
WP_075611831.1\|1031712_1032231_+	sigma-70 family RNA polymerase sigma factor	A0A2H4J6J3	uncultured_Caudovirales_phage	8.9e-35	46.2
WP_024423266.1\|1032382_1033027_+	helix-turn-helix domain-containing protein	A0A2P1JTW4	Anoxybacillus_phage	2.9e-43	44.7
WP_075611830.1\|1033023_1034337_+\|terminase	PBSX family phage terminase large subunit	M4ZRM5	Bacillus_phage	1.0e-151	61.8
WP_075611829.1\|1034333_1035791_+\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	4.2e-138	52.5
WP_075611828.1\|1035829_1036918_+\|terminase	terminase	A0A1B1P7E4	Bacillus_phage	1.5e-63	41.2
WP_024425904.1\|1036940_1037864_+\|capsid	phage major capsid protein	A0A1B1P7E3	Bacillus_phage	1.2e-109	64.6
WP_075611827.1\|1037877_1038261_+	DUF3199 family protein	NA	NA	NA	NA
WP_041088568.1\|1038257_1038614_+	DUF3599 family protein	NA	NA	NA	NA
WP_041088570.1\|1038610_1039108_+	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	3.5e-36	45.0
WP_075611826.1\|1039112_1039568_+\|portal	phage portal protein	NA	NA	NA	NA
WP_024425900.1\|1039554_1039767_+	hypothetical protein	NA	NA	NA	NA
WP_041088573.1\|1039770_1041117_+\|portal	phage portal protein	S5MNC1	Brevibacillus_phage	4.6e-75	39.8
WP_024423257.1\|1041118_1041562_+\|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	5.8e-27	46.5
WP_073207186.1\|1041846_1041936_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_012011040.1\|1042088_1042529_+\|portal	phage portal protein	A0A0A7RTY8	Clostridium_phage	9.9e-11	36.8
WP_095357030.1\|1042570_1042708_+	hypothetical protein	NA	NA	NA	NA
WP_075611825.1\|1042708_1046788_+	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	9.8e-44	45.5
WP_041085438.1\|1046780_1047449_+	LysM peptidoglycan-binding domain-containing protein	A0A0K2SUI2	Clostridium_phage	2.7e-23	30.1
WP_075611824.1\|1047461_1048472_+\|portal	phage portal protein	H7BV96	unidentified_phage	6.0e-35	28.2
WP_024423253.1\|1048468_1048735_+	DUF2577 domain-containing protein	S6C459	Thermus_phage	2.1e-08	37.5
WP_041085444.1\|1048749_1049172_+	DUF2634 domain-containing protein	A0A1V0DZX2	Clostridioides_phage	4.6e-05	34.1
WP_075611823.1\|1049164_1050214_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	2.1e-67	42.9
WP_073979161.1\|1050197_1051121_+	YmfQ family protein	A0A0A7RTT8	Clostridium_phage	7.2e-11	29.2
WP_047203992.1\|1051132_1051516_+	hypothetical protein	NA	NA	NA	NA
WP_075611822.1\|1051531_1052410_+	hypothetical protein	NA	NA	NA	NA
WP_075611821.1\|1052420_1052750_+\|portal	phage portal protein	A0A2H4JCI0	uncultured_Caudovirales_phage	3.1e-09	36.5
WP_075611820.1\|1052746_1052920_+\|portal	phage portal protein	A0A2H4JAA1	uncultured_Caudovirales_phage	2.0e-07	46.9
WP_075611819.1\|1052927_1054055_+	hypothetical protein	NA	NA	NA	NA
WP_075611818.1\|1054103_1055489_+	hypothetical protein	A0A1P8CWR7	Bacillus_phage	4.1e-26	44.1
WP_075611817.1\|1055501_1055822_+	hypothetical protein	O64053	Bacillus_phage	2.5e-19	53.7
WP_075611816.1\|1055821_1055962_+	XkdX family protein	NA	NA	NA	NA
WP_012011023.1\|1055998_1056211_+	hypothetical protein	A0A290GDY2	Caldibacillus_phage	5.1e-13	55.1
WP_019743388.1\|1056222_1056486_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	7.7e-27	69.0
WP_075611815.1\|1056505_1057309_+	N-acetylmuramoyl-L-alanine amidase	Q9ZXD7	Bacillus_phage	1.0e-61	68.5
WP_075612413.1\|1057546_1057957_+	hypothetical protein	A0A2H4J4R7	uncultured_Caudovirales_phage	2.2e-68	95.6
WP_075611814.1\|1058129_1059005_+	hypothetical protein	A0A0S2GLF7	Bacillus_phage	5.3e-40	34.5

DBSCAN-SWA_5

1312966 : 1376890

Bacillus_phage(10.0%)

coat,tRNA,protease,integrase

attL 1306985:1307000|attR 1360213:1360228

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1306985:1307000	attL	NA	NA	NA	NA
WP_075611731.1\|1312966_1313506_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	3.3e-48	59.5
WP_075611730.1\|1314270_1314732_+	hypothetical protein	NA	NA	NA	NA
WP_073978769.1\|1314751_1315153_+	DUF1878 family protein	NA	NA	NA	NA
WP_081378149.1\|1315285_1315990_+	DUF4241 domain-containing protein	NA	NA	NA	NA
WP_075611728.1\|1316075_1316471_-	hypothetical protein	V5UQY3	Oenococcus_phage	1.7e-33	53.5
WP_003216493.1\|1316810_1316954_+	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_075611727.1\|1316968_1318474_+	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	1.2e-34	23.9
WP_073980032.1\|1318470_1319655_+	D-alanyl-lipoteichoic acid biosynthesis protein DltB	A0A125RNP0	Pseudomonas_phage	1.1e-16	27.9
WP_024423191.1\|1319676_1319913_+	D-alanine--poly(phosphoribitol) ligase subunit 2	NA	NA	NA	NA
WP_075611726.1\|1319912_1321079_+	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_034279788.1\|1321174_1321594_+	DUF1232 domain-containing protein	A0A2I7S9Z5	Vibrio_phage	1.5e-08	30.5
WP_041086492.1\|1321826_1322870_-	lactonase family protein	NA	NA	NA	NA
WP_039180440.1\|1323303_1324218_+	branched-chain-amino-acid transaminase	NA	NA	NA	NA
WP_075611725.1\|1324595_1326320_+	acetolactate synthase large subunit	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	2.3e-63	30.6
WP_007501584.1\|1326316_1326835_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_024423187.1\|1326853_1327882_+	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_039180437.1\|1327868_1329422_+	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	7.1e-11	26.2
WP_075611724.1\|1329440_1330538_+	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_039180431.1\|1330578_1331994_+	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_024423183.1\|1332007_1332607_+	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_041086486.1\|1332732_1333740_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_034279803.1\|1333980_1335255_+	trigger factor	NA	NA	NA	NA
WP_024423180.1\|1335506_1336772_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	8.6e-148	64.0
WP_075611723.1\|1336908_1338570_+\|protease	ATP-dependent protease LonB	NA	NA	NA	NA
WP_039180421.1\|1338741_1341066_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	7.0e-180	43.6
WP_024423177.1\|1341062_1341650_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_034279808.1\|1341859_1342345_-	hypothetical protein	NA	NA	NA	NA
WP_039180415.1\|1342587_1343955_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_075611722.1\|1343962_1344793_+	cytochrome C assembly protein	NA	NA	NA	NA
WP_024423173.1\|1344830_1345763_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_075611721.1\|1345759_1346551_+	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_029706177.1\|1346550_1347519_+	porphobilinogen synthase	NA	NA	NA	NA
WP_039180405.1\|1347546_1348839_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_075611720.1\|1348974_1350300_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_075611719.1\|1350337_1351369_+\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_003216497.1\|1351419_1351608_-	hypothetical protein	NA	NA	NA	NA
WP_041086475.1\|1352065_1354708_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	9.1e-160	41.5
WP_075611718.1\|1354773_1356078_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_041086471.1\|1356225_1356957_+	prepilin peptidase	NA	NA	NA	NA
WP_041086874.1\|1357113_1358130_+	SPOR domain-containing protein	NA	NA	NA	NA
WP_041086469.1\|1358307_1358877_+	septum formation inhibitor Maf	NA	NA	NA	NA
WP_080708030.1\|1358909_1359599_+	JAB domain-containing protein	NA	NA	NA	NA
WP_007501538.1\|1359689_1360709_+	rod shape-determining protein	NA	NA	NA	NA
1360213:1360228	attR	NA	NA	NA	NA
WP_041086466.1\|1360736_1361636_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_041086464.1\|1361632_1362151_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_041086462.1\|1362205_1362889_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_017358134.1\|1362891_1363695_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_075611717.1\|1363875_1364667_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_075611716.1\|1364659_1365529_+	stage IV sporulation protein FB	NA	NA	NA	NA
WP_003216781.1\|1365680_1365989_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_034279847.1\|1366003_1366342_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003216586.1\|1366354_1366639_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_024423157.1\|1366895_1367489_+	sporulation protein	NA	NA	NA	NA
WP_039180364.1\|1367510_1368797_+	GTPase ObgE	NA	NA	NA	NA
WP_008342790.1\|1368852_1369296_+	ACT domain-containing protein	NA	NA	NA	NA
WP_024423155.1\|1369314_1370193_+	prephenate dehydratase	NA	NA	NA	NA
WP_075611714.1\|1371999_1373574_+	L-aspartate oxidase	NA	NA	NA	NA
WP_075611713.1\|1373555_1374419_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_073979795.1\|1374405_1375515_+	quinolinate synthase NadA	NA	NA	NA	NA
WP_075611712.1\|1375645_1376890_+\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA

DBSCAN-SWA_6

1710528 : 1716916

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075611585.1\|1710528_1711179_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.3e-40	40.8
WP_075611584.1\|1711190_1711817_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.9e-55	56.9
WP_075611583.1\|1711843_1712308_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	9.4e-44	70.3
WP_039179637.1\|1712421_1712775_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_075611582.1\|1712799_1713324_-	DUF309 domain-containing protein	NA	NA	NA	NA
WP_012010430.1\|1713414_1713507_-	YjcZ family sporulation protein	NA	NA	NA	NA
WP_024422848.1\|1713717_1714476_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.3e-10	39.2
WP_024422847.1\|1714465_1715059_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.0e-15	36.0
WP_041085975.1\|1715172_1715652_+	DUF3907 family protein	NA	NA	NA	NA
WP_075611581.1\|1715764_1716916_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	5.4e-24	37.7

DBSCAN-SWA_7

1754639 : 1762349

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003215863.1\|1754639_1754918_+	non-specific DNA-binding protein Hbs	A7KV42	Bacillus_phage	5.6e-28	74.2
WP_003215789.1\|1755108_1755678_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	1.8e-49	57.3
WP_008344541.1\|1755702_1755933_+	trp RNA-binding attenuation protein MtrB	NA	NA	NA	NA
WP_041085908.1\|1756048_1756816_+	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_041085906.1\|1756819_1757524_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_041085904.1\|1757548_1758511_+	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	5.0e-07	25.6
WP_024422808.1\|1758640_1759087_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.0e-27	42.3
WP_075611568.1\|1759232_1760012_+	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_024422806.1\|1760085_1761258_+	chorismate synthase	A0A291AU41	Pandoravirus	2.6e-42	35.4
WP_041085899.1\|1761257_1762349_+	3-dehydroquinate synthase	E5ERI4	Ostreococcus_lucimarinus_virus	8.2e-22	27.0

DBSCAN-SWA_8

2135745 : 2142006

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024424083.1\|2135745_2136705_-	stage V sporulation protein K	G3MAX6	Bacillus_virus	3.9e-52	39.6
WP_047203907.1\|2137025_2137784_+	N-acetylmuramoyl-L-alanine amidase	E5DV68	Deep-sea_thermophilic_phage	6.9e-52	50.0
WP_047203906.1\|2137851_2138469_-	hypothetical protein	A0A127AYS1	Bacillus_phage	7.8e-46	45.8
WP_034662137.1\|2138553_2139534_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4JMU8	Bacillus_phage	5.4e-150	80.2
WP_034281935.1\|2139551_2141654_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	U5PY35	Bacillus_phage	0.0e+00	83.4
WP_008360380.1\|2141613_2142006_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	S5MA49	Bacillus_phage	6.1e-28	54.2

DBSCAN-SWA_9

2784110 : 2845319

uncultured_Caudovirales_phage(70.97%)

terminase,plate,integrase,capsid,holin,portal

attL 2787216:2787230|attR 2853072:2853086

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075611190.1\|2784110_2784368_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	6.4e-18	55.4
WP_075611189.1\|2784623_2785628_-	DNA relaxase NicK	A0A1S5SEX3	Streptococcus_phage	4.1e-60	37.9
WP_075611188.1\|2785651_2787094_-	ATP-binding protein	A0A1S5SFB5	Streptococcus_phage	2.5e-111	46.1
2787216:2787230	attL	NA	NA	NA	NA
WP_075611186.1\|2787504_2787867_-	YdcP family protein	NA	NA	NA	NA
WP_075611185.1\|2787903_2788107_-	hypothetical protein	NA	NA	NA	NA
WP_073979206.1\|2788446_2788731_-	hypothetical protein	NA	NA	NA	NA
WP_155761613.1\|2788789_2789005_-	hypothetical protein	NA	NA	NA	NA
WP_073979208.1\|2789031_2789226_-	ICEBs1 excisionase	A0A0A8WI91	Clostridium_phage	6.1e-05	42.3
WP_073979209.1\|2789387_2789759_+	helix-turn-helix transcriptional regulator	A0A090D830	Clostridium_phage	1.0e-08	32.5
WP_073979210.1\|2789755_2790271_+	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	4.4e-10	31.9
WP_073979211.1\|2790286_2791417_+\|integrase	site-specific integrase	Q8SBN2	Clostridium_phage	6.2e-41	34.5
WP_075611183.1\|2791832_2792978_+	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_041089716.1\|2793017_2793530_-	signal peptidase I	NA	NA	NA	NA
WP_024425492.1\|2793529_2794147_-	TVP38/TMEM64 family protein	NA	NA	NA	NA
WP_041089714.1\|2794308_2794677_+	hypothetical protein	A0A2H4J238	uncultured_Caudovirales_phage	4.9e-11	32.8
WP_075611182.1\|2794739_2795696_-	LCP family protein	NA	NA	NA	NA
WP_075612369.1\|2795872_2796151_-	barnase inhibitor	NA	NA	NA	NA
WP_075611181.1\|2796216_2797386_-	MFS transporter	NA	NA	NA	NA
WP_075611180.1\|2797531_2798971_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_039177626.1\|2799002_2799485_-	hypothetical protein	NA	NA	NA	NA
WP_081378173.1\|2799652_2800591_-	NERD domain-containing protein	A0A1L2JY40	Aeribacillus_phage	5.9e-29	30.1
WP_075611177.1\|2802043_2802898_+	Abi family protein	A3QSC6	Clostridium_virus	1.6e-44	39.2
WP_075611176.1\|2803041_2803284_-	helix-turn-helix domain-containing protein	A0A2H4JDR0	uncultured_Caudovirales_phage	6.0e-34	93.8
WP_075611174.1\|2803708_2804527_-	peptidase M15	A0A2H4J4U2	uncultured_Caudovirales_phage	1.1e-119	96.3
WP_075611173.1\|2804584_2804848_-\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	1.0e-39	98.9
WP_025092921.1\|2804863_2805076_-	hypothetical protein	A0A290GDY2	Caldibacillus_phage	6.0e-14	58.0
WP_080772252.1\|2805137_2805278_-	XkdX family protein	A0A2H4JD72	uncultured_Caudovirales_phage	3.6e-07	56.8
WP_075611172.1\|2805277_2805652_-	hypothetical protein	M4ZR44	Bacillus_phage	9.3e-10	41.9
WP_075611171.1\|2807012_2807642_-	DUF2612 domain-containing protein	A0A2H4J4S3	uncultured_Caudovirales_phage	2.5e-108	96.7
WP_075611170.1\|2807638_2808814_-\|plate	baseplate J/gp47 family protein	A0A2H4J8D2	uncultured_Caudovirales_phage	1.8e-208	97.2
WP_075611169.1\|2808803_2809166_-	DUF2634 domain-containing protein	A0A2H4J4S8	uncultured_Caudovirales_phage	1.1e-44	83.3
WP_008348688.1\|2809162_2809507_-	hypothetical protein	A0A2H4JDQ2	uncultured_Caudovirales_phage	1.5e-59	98.2
WP_075611168.1\|2809506_2810502_-	hypothetical protein	A0A2H4J4T4	uncultured_Caudovirales_phage	8.5e-159	98.8
WP_075611167.1\|2810488_2810839_-	hypothetical protein	A0A2H4J6L1	uncultured_Caudovirales_phage	4.0e-55	92.2
WP_045034736.1\|2810849_2811395_-	LysM peptidoglycan-binding domain-containing protein	A0A2H4JD33	uncultured_Caudovirales_phage	6.2e-95	99.4
WP_155761821.1\|2811394_2814061_-	transglycosylase SLT domain-containing protein	A0A2H4JA91	uncultured_Caudovirales_phage	0.0e+00	91.4
WP_075612368.1\|2815169_2815472_-	hypothetical protein	A0A2H4J4Q2	uncultured_Caudovirales_phage	1.6e-31	70.0
WP_008348701.1\|2815563_2815965_-	DUF3277 family protein	A0A2H4J4R5	uncultured_Caudovirales_phage	4.0e-59	89.1
WP_075611165.1\|2815979_2817014_-	DUF3383 family protein	A0A2H4J8B9	uncultured_Caudovirales_phage	1.3e-189	98.5
WP_081378175.1\|2817018_2817498_-	hypothetical protein	A0A2H4J4R9	uncultured_Caudovirales_phage	5.6e-84	96.9
WP_081378176.1\|2817490_2817841_-	hypothetical protein	A0A2H4JDP3	uncultured_Caudovirales_phage	8.9e-55	89.7
WP_075611163.1\|2817840_2818341_-	hypothetical protein	A0A2H4J4S5	uncultured_Caudovirales_phage	5.7e-87	97.6
WP_075611162.1\|2818345_2818681_-	hypothetical protein	A0A2H4J6J9	uncultured_Caudovirales_phage	5.2e-52	94.6
WP_081378177.1\|2818680_2819544_-	hypothetical protein	A0A2H4JD21	uncultured_Caudovirales_phage	4.5e-148	95.1
WP_075611160.1\|2819701_2820604_-\|capsid	phage major capsid protein	A0A2H4JCG0	uncultured_Caudovirales_phage	2.4e-104	64.0
WP_075611159.1\|2820616_2821198_-	DUF4355 domain-containing protein	A0A2H4J4P4	uncultured_Caudovirales_phage	8.3e-82	84.5
WP_075611158.1\|2821231_2822677_-\|portal	phage portal protein	A0A2H4J4Q7	uncultured_Caudovirales_phage	8.0e-267	96.5
WP_075611157.1\|2822681_2823884_-\|terminase	PBSX family phage terminase large subunit	A0A2H4J8B0	uncultured_Caudovirales_phage	9.7e-234	99.0
WP_075611156.1\|2823870_2824626_-	hypothetical protein	A0A2H4J4R0	uncultured_Caudovirales_phage	1.1e-118	88.3
WP_075611155.1\|2824669_2824897_-	hypothetical protein	NA	NA	NA	NA
WP_155761585.1\|2825029_2825578_-	hypothetical protein	NA	NA	NA	NA
WP_075611153.1\|2825721_2826177_-	hypothetical protein	A0A2H4J4R7	uncultured_Caudovirales_phage	4.2e-81	98.7
WP_075611152.1\|2826180_2826669_-	hypothetical protein	A0A2H4J6J3	uncultured_Caudovirales_phage	4.7e-78	93.8
WP_075611151.1\|2826896_2827085_-	hypothetical protein	NA	NA	NA	NA
WP_075611151.1\|2827110_2827299_-	hypothetical protein	NA	NA	NA	NA
WP_075611150.1\|2827324_2827570_-	hypothetical protein	NA	NA	NA	NA
WP_075611149.1\|2827586_2827877_-	hypothetical protein	NA	NA	NA	NA
WP_075611148.1\|2827888_2828314_-	hypothetical protein	A0A2H4J8A0	uncultured_Caudovirales_phage	1.4e-70	93.6
WP_075611147.1\|2828310_2828520_-	hypothetical protein	NA	NA	NA	NA
WP_075611146.1\|2828535_2828805_-	hypothetical protein	A0A2H4JDM6	uncultured_Caudovirales_phage	2.4e-28	73.0
WP_075611145.1\|2829180_2829573_-	hypothetical protein	U5PU08	Bacillus_phage	1.1e-26	51.6
WP_075611144.1\|2829569_2830025_-	hypothetical protein	NA	NA	NA	NA
WP_075611143.1\|2830024_2830624_-	dUTPase	A0A1L2JY27	Aeribacillus_phage	1.2e-27	39.4
WP_075611142.1\|2830620_2830827_-	hypothetical protein	NA	NA	NA	NA
WP_075611141.1\|2830854_2832303_-	DNA cytosine methyltransferase	A0A1I9KFD6	Aeromonas_phage	1.1e-111	52.5
WP_075611140.1\|2832299_2832548_-	hypothetical protein	A0A2H4JA61	uncultured_Caudovirales_phage	2.3e-33	90.1
WP_075611139.1\|2832565_2832769_-	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	1.9e-25	86.2
WP_075611137.1\|2833116_2833572_-	DUF1064 domain-containing protein	A0A2H4J891	uncultured_Caudovirales_phage	2.6e-70	90.1
WP_075611136.1\|2833690_2833909_-	hypothetical protein	A0A2H4JDM0	uncultured_Caudovirales_phage	2.6e-36	97.2
WP_075611135.1\|2834180_2835110_-	ATP-binding protein	Q0H276	Geobacillus_phage	7.2e-43	42.1
WP_075611134.1\|2835012_2835672_-	DnaD domain protein	A0A2H4J6G9	uncultured_Caudovirales_phage	1.7e-70	70.3
WP_075611133.1\|2835833_2836676_-	recombinase RecT	A0A2H4JCY8	uncultured_Caudovirales_phage	1.4e-149	97.1
WP_075611132.1\|2836675_2837626_-	hypothetical protein	A0A2H4JA52	uncultured_Caudovirales_phage	2.6e-173	97.8
WP_075611131.1\|2837628_2837808_-	hypothetical protein	A0A2H4JCC7	uncultured_Caudovirales_phage	1.2e-23	89.8
WP_075611130.1\|2838018_2838303_-	hypothetical protein	NA	NA	NA	NA
WP_075611129.1\|2838299_2838869_-	helix-turn-helix transcriptional regulator	A0A2H4J884	uncultured_Caudovirales_phage	1.1e-81	79.3
WP_075611128.1\|2838935_2839634_-	phage antirepressor	A0A141E0Q0	Streptococcus_phage	6.2e-39	44.4
WP_075611127.1\|2839630_2839936_-	hypothetical protein	A0A2H4JDL0	uncultured_Caudovirales_phage	5.1e-22	51.0
WP_075611126.1\|2839947_2840172_-	helix-turn-helix transcriptional regulator	A0A2H4J4N8	uncultured_Caudovirales_phage	1.2e-33	95.9
WP_075611125.1\|2840334_2840694_+	helix-turn-helix transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	1.3e-56	97.5
WP_075611124.1\|2840845_2841778_+	hypothetical protein	A0A2H4JCX8	uncultured_Caudovirales_phage	4.0e-126	79.4
WP_075611123.1\|2841844_2842348_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	2.2e-83	90.4
WP_075611122.1\|2842361_2843555_+\|integrase	site-specific integrase	S6C485	Thermus_phage	7.4e-85	42.1
WP_075611121.1\|2843579_2843876_-	competence protein ComK	NA	NA	NA	NA
WP_008348804.1\|2844165_2844402_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_041089704.1\|2844458_2845319_-	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	8.3e-54	44.2
2853072:2853086	attR	NA	NA	NA	NA

DBSCAN-SWA_10

3191477 : 3201373

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039176947.1\|3191477_3193016_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.1e-76	52.1
WP_075610985.1\|3193031_3193601_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.9e-31	41.1
WP_039176942.1\|3193597_3194638_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.6e-65	44.3
WP_024424615.1\|3194734_3196165_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.9e-51	32.5
WP_075610984.1\|3196140_3198372_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.1e-158	41.8
WP_024424510.1\|3198355_3199039_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003214349.1\|3199035_3199290_-	phosphoribosylformylglycinamidine synthase subunit PurS	M4QPE7	Synechococcus_phage	1.6e-05	34.6
WP_039176936.1\|3199282_3200005_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3G7P8	Synechococcus_phage	2.0e-45	42.8
WP_024426701.1\|3200077_3201373_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	2.9e-18	26.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage