CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007389	Thermosipho melanesiensis strain 431, complete genome	6 crisprs	cas2,cas1,cas4,cas3,cas5,cas7b,cas8b1,cas6,DEDDh,csa3,cas3HD,casR,csm6,cmr1gr7,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,csx1,csm2gr11,csm3gr7,csm4gr5,csm5gr7	0	2	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007389_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007389_1

137986-138684

Orphan

Consensus_repeat	Method
GTTTCTACCTTACCTTGGAGGAATTGAAAC	PILER-CR
GTTTCTACCTTACCTTGGAGGAATTGAAAC	CRISPRCasFinder
NNGTTTCTACCTTACCTTGGAGGAATTGAAAC	CRT

10 spacers

The CRISPR arrays of NZ_CP007389_1

>merge|NZ_CP007389|1|137986-138684|PILER-CR,CRISPRCasFinder,CRT
GTTTCTACCTTACCTTGGAGGAATTGAAACTATATCTTATTGAGGCTAAGTGGACGTGCATTTTATGTTTCTACCTTACCTTGGAGGAATTGAAACATGTTGGATTTCTTCTTTTATCAAGTGTGATAGAAATAAGTTTCTACCTTACCTTGGAGGAATTGAAACTAACAAAAAATGTTGTATTGGATTGACGTCGTACTAAGTTTCTACCTTACCTTGGAGGAATTGAAACAGACATTAACGCAAATACTGCTCTTGCCGCTCTTGCTTCGTTTCTACCTTACCTTGGAGGAATTGAAACTTAAGTAAGTTTTTGGATGGCAAGAGAAGTTTAAATGTTTCTACCTTACCTTGGAGGAATTGAAACTGTGGATGAAAGAATTAGAATTCCCACACCATACACGGTTTCTACCTTACCTTGGAGGAATTGAAACTGTACGATGACTCTGGTCGGATTCTACACTCGTTTGAGTTTCTACCTTACCTTGGAGGAATTGAAACAAATATTGGTGGTGTTCTTCCTCAAGAATTTTTGGAGTTTCTACCTTACCTTGGAGGAATTGAAACACATTATTGTCATCCTCTGTAACTAGTTACAACACGCCGTTTTTTCTTACCTTTGAGAAATTGAAACATCTCTCCTTGAGGGAAATTCGTTGAGGCCCTTTGAACTTTTTACCCTACCTTGAAAGTTGAAAC

>NZ_CP007389|1|1|137986-138552|PILER-CR
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TATATCTTATTGAGGCTAAGTGGACGTGCATTTTAT
GTTTCTACCTTACCTTGGAGGAATTGAAAC	ATGTTGGATTTCTTCTTTTATCAAGTGTGATAGAAATAA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TAACAAAAAATGTTGTATTGGATTGACGTCGTACTAA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	AGACATTAACGCAAATACTGCTCTTGCCGCTCTTGCTTC
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TTAAGTAAGTTTTTGGATGGCAAGAGAAGTTTAAAT
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TGTGGATGAAAGAATTAGAATTCCCACACCATACACG
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TGTACGATGACTCTGGTCGGATTCTACACTCGTTTGA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	AAATATTGGTGGTGTTCTTCCTCAAGAATTTTTGGA
GTTTCTACCTTACCTTGGAGGAATTGAAAC

>NZ_CP007389|1|1|137986-138619|CRISPRCasFinder
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TATATCTTATTGAGGCTAAGTGGACGTGCATTTTAT
GTTTCTACCTTACCTTGGAGGAATTGAAAC	ATGTTGGATTTCTTCTTTTATCAAGTGTGATAGAAATAA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TAACAAAAAATGTTGTATTGGATTGACGTCGTACTAA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	AGACATTAACGCAAATACTGCTCTTGCCGCTCTTGCTTC
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TTAAGTAAGTTTTTGGATGGCAAGAGAAGTTTAAAT
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TGTGGATGAAAGAATTAGAATTCCCACACCATACACG
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TGTACGATGACTCTGGTCGGATTCTACACTCGTTTGA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	AAATATTGGTGGTGTTCTTCCTCAAGAATTTTTGGA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	ACATTATTGTCATCCTCTGTAACTAGTTACAACACGC
CGTTTTTTCTTACCTTTGAGAAATTGAAAC

>NZ_CP007389|1|1|137986-138684|CRT
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TATATCTTATTGAGGCTAAGTGGACGTGCATTTTAT
GTTTCTACCTTACCTTGGAGGAATTGAAAC	ATGTTGGATTTCTTCTTTTATCAAGTGTGATAGAAATAA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TAACAAAAAATGTTGTATTGGATTGACGTCGTACTAA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	AGACATTAACGCAAATACTGCTCTTGCCGCTCTTGCTTC
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TTAAGTAAGTTTTTGGATGGCAAGAGAAGTTTAAAT
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TGTGGATGAAAGAATTAGAATTCCCACACCATACACG
GTTTCTACCTTACCTTGGAGGAATTGAAAC	TGTACGATGACTCTGGTCGGATTCTACACTCGTTTGA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	AAATATTGGTGGTGTTCTTCCTCAAGAATTTTTGGA
GTTTCTACCTTACCTTGGAGGAATTGAAAC	ACATTATTGTCATCCTCTGTAACTAGTTACAACACGC
CGTTTTTTCTTACCTTTGAGAAATTGAAAC	ATCTCTCCTTGAGGGAAATTCGTTGAGGCCCTTTG
AACTTTTTACCCTACCTTGAAAGTTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007389.1\|WP_012056372.1\|141341_143066_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP007389.1\|WP_143610970.1\|147550_147949_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_143610966.1\|143049_143418_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP007389.1\|WP_012056363.1\|129857_132002_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012056370.1\|138742_139270_+\|NLP/P60-protein	unknown	unknown	gnl\|CDD\|366353
NZ_CP007389.1\|WP_012056374.1\|143604_147528_+\|alpha-2-macroglobulin	unknown	unknown	gnl\|CDD\|225248
NZ_CP007389.1\|WP_143610951.1\|132012_132624_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_004104037.1\|126231_126495_+\|stage-V-sporulation-protein-S	unknown	unknown	gnl\|CDD\|377254
NZ_CP007389.1\|WP_012056362.1\|128130_129852_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP007389.1\|WP_012056378.1\|149929_150448_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012056379.1\|150466_151801_-\|SidA/IucD/PvdA-family-monooxygenase	unknown	unknown	gnl\|CDD\|181958
NZ_CP007389.1\|WP_012056377.1\|148570_149785_-\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341465
NZ_CP007389.1\|WP_012056365.1\|132634_135001_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012056366.1\|135000_135528_-\|bifunctional-nuclease-family-protein	unknown	unknown	gnl\|CDD\|376830
NZ_CP007389.1\|WP_143610968.1\|147896_148529_+\|DUF1175-family-protein	unknown	unknown	gnl\|CDD\|377683
NZ_CP007389.1\|WP_012056371.1\|139503_141345_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP007389.1\|WP_012056361.1\|126543_128091_-\|bifunctional-UDP-sugar-hydrolase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|236566
NZ_CP007389.1\|WP_012056368.1\|136266_137436_-\|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl\|CDD\|234960
NZ_CP007389.1\|WP_012056369.1\|137472_137745_-\|metal-sensing-transcriptional-repressor	unknown	unknown	gnl\|CDD\|197394
NZ_CP007389.1\|WP_012056367.1\|135514_136270_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251

Protein	Function_ID	Function_description	E-value
NZ_CP007389.1\|WP_012056372.1\|141341_143066_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.46335e-164
NZ_CP007389.1\|WP_012056368.1\|136266_137436_-\|tRNA-4-thiouridine(8)-synthase-ThiI	gnl\|CDD\|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	0
NZ_CP007389.1\|WP_012056370.1\|138742_139270_+\|NLP/P60-protein	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	6.16267e-15
NZ_CP007389.1\|WP_012056374.1\|143604_147528_+\|alpha-2-macroglobulin	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	1.23495e-59
NZ_CP007389.1\|WP_004104037.1\|126231_126495_+\|stage-V-sporulation-protein-S	gnl\|CDD\|377254	pfam04232, SpoVS, Stage V sporulation protein S (SpoVS). In Bacillus subtilis this protein interferes with sporulation at an early stage and this inhibitory effect is overcome by SpoIIB and SpoVG. SpoVS seems to play a positive role in allowing progression beyond stage V of sporulation. Null mutations in the spoVS gene block sporulation at stage V, impairing the development of heat resistance and coat assembly.	1.96516e-45
NZ_CP007389.1\|WP_012056367.1\|135514_136270_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.99789e-46
NZ_CP007389.1\|WP_012056379.1\|150466_151801_-\|SidA/IucD/PvdA-family-monooxygenase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	7.19717e-147
NZ_CP007389.1\|WP_012056377.1\|148570_149785_-\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341465	cd08186, Fe-ADH-like, Iron-containing alcohol dehydrogenase. This family contains iron-containing alcohol dehydrogenase (ADH) which catalyzes the reduction of acetaldehyde to alcohol with NADP as cofactor. The ADH of hyperthermophilic archaeon Thermococcus hydrothermalis oxidizes a series of primary aliphatic and aromatic alcohols, preferentially from C2 to C8, but is also active towards methanol and glycerol, and is stereospecific for monoterpenes. It has been suggested that the type III ADHs in microorganisms are involved in acetaldehyde detoxication rather than in alcohol turnover.	0
NZ_CP007389.1\|WP_012056366.1\|135000_135528_-\|bifunctional-nuclease-family-protein	gnl\|CDD\|376830	pfam02577, DNase-RNase, Bifunctional nuclease. This family is a bifunctional nuclease, with both DNase and RNase activity. It forms a wedge-shaped dimer, with each monomer being triangular in shape. A large groove at the thick end of the wedge contains a possible active site.	1.52258e-52
NZ_CP007389.1\|WP_012056362.1\|128130_129852_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.14858e-154
NZ_CP007389.1\|WP_143610968.1\|147896_148529_+\|DUF1175-family-protein	gnl\|CDD\|377683	pfam06672, DUF1175, Protein of unknown function (DUF1175). This family consists of several hypothetical bacterial proteins of around 210 residues in length. The function of this family is unknown.	2.13456e-96
NZ_CP007389.1\|WP_012056371.1\|139503_141345_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP007389.1\|WP_012056361.1\|126543_128091_-\|bifunctional-UDP-sugar-hydrolase/5'-nucleotidase	gnl\|CDD\|236566	PRK09558, ushA, bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed.	0
NZ_CP007389.1\|WP_143610966.1\|143049_143418_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.09261e-22
NZ_CP007389.1\|WP_012056369.1\|137472_137745_-\|metal-sensing-transcriptional-repressor	gnl\|CDD\|197394	cd10159, CsoR-like_DUF156_2, Uncharacterized family 2; belongs to a superfamily containing transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this family was previously known as part of DUF156. Uncharacterized family 2, belonging to a larger superfamily that contains various transcriptional regulators that respond to different stressors such as Cu(I), Ni(I), sulfite, and formaldehyde, and includes CsoRs (copper-sensitive operon repressors). CsoRs form homotetramers (dimer of dimers). In Mycobacterium tuberculosis CsoR, within each dimer, two Cys residues on opposite subunits, along with a His residue, bind the Cu(I) ion (forming a triagonal S2N coordination complex, C-H-C). These residues are conserved in the majority of members of this superfamily, including this family, and a conserved Tyr and a Glu residue that facilitate allosteric regulation of DNA binding for CsoRs are also conserved.	4.66545e-36

>NZ_CP007389.1|WP_012056369.1|137472_137745_-|metal-sensing-transcriptional-repressor
MKHKNALKTLKNARGQLEAVMKMIEEGRYCIDISKQILATISLLKKANVEVLNSHLETCVKSAVSSNNPEEVDVKIKELEEVIKYLNKIV
>NZ_CP007389.1|WP_012056368.1|136266_137436_-|tRNA-4-thiouridine(8)-synthase-ThiI
MEPVVVVRYSEIGLKGKNRGYFEKKLIDNIRKIVKPPEVNKRYGRIIIRLKGMSFEEIKERLRYVFGIHSFSYAYATSHDLDEIKEAVKELLTLSLKDEKTFKVQTKRSYKQFPLTSHELSAYIGAFVLEKFKNLKVDVHNPEITVGIELKEKEAFIFVGKERLYGGFPVGVSGKAILLLSGGIDSPVAGWYMLKRGLKIETLSFLSPPFTSEKSAKKVLDLASILAKYSPEPIKANIVSFTEVQQYIKKNAPDKYSLILQRRSMMRIANKLSRKRHAKALITGENIAQVASQTLSNLASIEDASNVPVLRPLIGFEKIDIVEKAKEIGTYEISILPYIDSCVAFAPKNPATNSSVEILRDLESGLKELHDLEEKAYREIKSYTLGRDL
>NZ_CP007389.1|WP_012056367.1|135514_136270_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MKNFFRFFYTIYFLVGAFIYIVVYGSIVLFIGFLVGLFNKNLSRRFVIHQIEVFGRMAFRLLGIKVHVFGEKPNLGENFIVVANHQSALDIPLIIGYVAPVAFIAKRELGKVPGINWYLKYLGSVLIDRGNVRKTAMALKQVVEKLKFGVHFIIFPEGTRSHDGNVLEFKKKSLEIAFKYKVKILPVSIWGVHKVLRKKSLMLNRYPVYIKIHELVDPSLFESEEDLRNHVRNIIIEGVKMLERRNFDEKS
>NZ_CP007389.1|WP_012056366.1|135000_135528_-|bifunctional-nuclease-family-protein
MKKVKVESLVLDKLNNSPVVILKVEGTKKILPIWIGACEASVIAMILENVSFERPLTHDLLLSMVEGLESKVEKVLINKIVDSTYYAKVILRDLTVTEEENEGYFLEFDARPSDAIILALKTNSPIYISNELYNTYTLQYDGESMDNDSEEFRKFIENLDINEFKKFKKGSQGDN
>NZ_CP007389.1|WP_012056365.1|132634_135001_-|hypothetical-protein
MNFFKNLLNKLKDFLGKLKVDKLIDILKSIYKRKVLLFLSVIVVVIVVSLSILLTQFLKNKSQIEINSQQEMTIVKNLYINIPKGAFPYEKSFNLNPLTPETAPTLFENAPFIDTVYDVIPKDGKKDFAYIPLTFRYYFPADYFYGIDYNNVALAYIPEDGSAYRIFPGSYIGKDEKGYFVEAQSFHSSKVGIVALNPKKQELGIKVLVEKLTPKPSILVVPGTDRNFKGYFKSDDTPDLNFWSVVFSDRTIMIYNYPLYEVRSKLYKDMVDDYFKRSELKSYIEFEAERLASELKRFKNFKFDIVAQDIGGLIVAYCLVLHPEISNVRNIAFVSVPFRGTNVANPVYFGSLLYGKSSDALSKIYNLDSNVISSLQTHIYTFIETINTYWSEILPDSKVLEKLVDLSKKNNVKMVSFMGTKPPFGVDVKGSTLEKFYPELVKGTGDGVVSVTSAKLKDMELVQIDGDAYTFYSSNDFVEKLKQLFEFGEIKIPEYKDDNYREYVSKTEKEKEVYLSKLRPYRFDGAKISDSIIVDFEKKLDFPGNQIAIFKSVIYTGGPDGLYGNGTKLLEGPIFNLKRSFGGVSFRTPNEIYFYSPAIKKKYNVVYVTDFLATQEGVYTANNAGEIVSFWDPSGNKIIDLKGQYGRIKVVDNYLIMFTNKQIYIPKLELLLNVPEFENKGIDISDVIIYRNEVLAVTRSYGFLFYDIGSTTGNYIGEGWIGNISISRVGNYLLTVGKNFITIIDIPERRVLRIIEKLDTEVLSTEVDDEYLYLVTKTGILKYKVKKD
>NZ_CP007389.1|WP_143610951.1|132012_132624_-|hypothetical-protein
MLHLFLGHYVADHGFTHNSKLRHLKGWDFVQHIIWSVFAILAFTFDTLLYTVPVVLFAFIAIHLFLDYLRIKVKKQLHYHLVELSGIVTALVFNIFVSTYFKTSYLSKEFVLYILGMALVTTALSYFFRNFYPAIEMYEDLEGISERLAFFIFYLANKPLLAFLALIFGFLFRLWKVKKFDHVWWISPTFAIVFSIFWKTIVF
>NZ_CP007389.1|WP_012056363.1|129857_132002_-|hypothetical-protein
MENKKELFIYLGFLVLILISIVLVVKLTQVEEPEISLLPPKIDSRNVVLKWNIKYKRDITFLSEVFLNDKKVYEGIDQEYKLLLKPGTYFWKVGLRFGNDYLETSQSSFTILNDIPKILNAKNVVDGQNVIFSWNVEDEDKTRCILYLSDGESEKTIDVENNTYEMLLSYGNYFWKVICEDEYGAKAESKLMEFKVIPKKVNFEIVEDKKGYLVRYENLDGAEYFLEIDNREIKLPPREYRLKIIPNVEHKLRLKVVFQTGDIIYSDYKIIYKKNNPPKLNVISPQNKLKGVVNSIVFKWEIEDEDRVLSTIYLGTSPQKLVPVVENYKATVYEVRNLKPNSKYYWKIKVNDGVNSVETPIYEFSTSPAIKILNVIGSKFDDYVYGYEYIDGEYIFGREGEKYFVLKDGIKFYIDDMPVDVKKKDGLTFLLSNSKDNIVLYALKGDVILWKKAYGGKFKDRAKKLLVENDGILVFGDTWSNDFLDIYGWSDIFLMKLDTNGNVIWKRNFGGRFLDEAVSISKYKDGYVILGNTFEKNKDLLVMYVDFSGKLKWVKFFGESDNELAKKILVKNDKIYVLSNVYFDKRRKITNDLNVYVLILNERGEKIEDYILGGSGDDICNDILIDGENIYLFGKTLSKDGDFVSYNNQKGYVDFFVSNLDNWAFVGGGYDFDEIKRAIKIGDKIRFVGETRSVNGLFEKHFGGLDIFIGELER
>NZ_CP007389.1|WP_012056362.1|128130_129852_-|ABC-transporter-ATP-binding-protein
MIREFLKRRIWFYFAGVITLIVVDTLQLIVPKFISRAVDSLNVETPDIGVAKLMAIGIIGIAIGMFFTRFFWRFFIIGSARKFTYEARKILYDKILSLDMSFFDKNRSGDLMANFTNDMNNIERMLGPGIVMMVDASFMSVITLFFMATSVGWKLTLIALIPLPFIMLISLVFGKFIYKRSKKVQDTFSDLSGFTEESIDGIRILKSFSILPKFENLFLDRANRNFRATLSLVKVWGIMWPLIHFISSLSYFITIAYGGPMVINQKITLGMFFAFNNYIGMIVWPLTAFGWVINIIQNGRASYTRILEVLKTQSKVVEPDNPVEIDEINDITIKNLNYKYPDSNRYVLKGVNLEIKRGQLVGIVGTVGSGKSTIVKIISKLYPVERGYVYINGYDINDIPSKIVRTKISYVPQETFLFSTSIKNNIAFGLDDFEEWQIKEYAMLSAVHSDIERFPKSYDTVVGERGVTLSGGQKQRITIARALIRNCDVFIFDDCLSAVDPETEEKIISSLRKSMESKTMIIITHRLKVLKDADIIYVFDDGQVVESGTHKQLMEIDGLYADMYKKQLIEESL
>NZ_CP007389.1|WP_012056361.1|126543_128091_-|bifunctional-UDP-sugar-hydrolase/5'-nucleotidase
MKNFKLFVVLFVIFAISLFATKVIIFHINDTHGHAWTFSEYHNPNIGGFAVIASIIDEERAKNPNVLFLHAGDINTGVPESDLLNALPDIFALNRMKLDAMAVGNHEFDKTRDVLMYQMDIAKFPFLSANIYKDGKPFFKPYIIKNVGGVKIAIFGLTTEETAILEPLYSRDLEFRNAIEVAKEIVPGLRKKADIVVALTHLGMGQAYEGNYTTSEELAKMVDGIDIIIDGHSHTKLEKAKVINNTIVVQAWEWGKIVGKLELDVENGKIENWNWTPIPVNLKVYKGKDEDGNSIYEFVGKEYKPTEYVKVPLDYFAKIGSEKLDTIIGETKILLDGERAHVRSGDTNLGHIITDAMLWKTGADIAFQNGGGIRASVEPGKITIRNILTVLPFGNTVYVMKMTGEQVMKVLEYAATIPEGKGAWLHVGGLVWKSEGGKVTEVMVNGKPLEMDKVYTIVTNNYMAGGGDGYSVLSENKASGYDTGFVLADVVVEYIQKALKGMIENYDDTPRYIRK
>NZ_CP007389.1|WP_004104037.1|126231_126495_+|stage-V-sporulation-protein-S
MEVLKVASGSNPNKVAGALAGVIREKGKAEVQAIGAGAVNQAVKAIAIARGYLAPSGIDLVCVPAFTDVNIENESRTALKFIVFPRE
>NZ_CP007389.1|WP_012056370.1|138742_139270_+|NLP/P60-protein
MDFWKIVLFSVLILMLSPFQVEVSSHEKQAWLKKVKEYDGVPYKWGGNSKEGIDCSGLVIELYHAIGIFLFKYENTLLLDVSADVLFKYNTRPIEFSELEPGDLIFYDTENDGIIDHVAIFAKKENGIIWVWDATDKIGNTVINKVSLRPAFELPHRYPKFGRPLKITNLLSEFF
>NZ_CP007389.1|WP_012056371.1|139503_141345_-|ABC-transporter-ATP-binding-protein
MSEKRPVHRGGPGGPIRGAVERPKNFRKALKRLLGYLKPYTVPLIIVFAMAITGTVFSIIAPKVLGKATTKLFQGFLAKRLFSNARIDLDGILQILIKVGILYGIFALFMYIQQYIMAGISQKVVKKLRTEIMEKLSKLPLKFYDSRTHGEILSRVTNDVDLISNTLNQSLTQLITSLVTIVGVIIMMLTISPLLTLVTLVTLPISISLIVFIVKKSQKYFKNQQNSLGSVNGHVEEMFSGLIVVKGYNREEDSIEKFEKYNEELFGASWKAQFISGITMPIMRFVGNLGYVIVSIMGGIMVTKRAIQLGDVQAFIQYSQQFNQPISQVANIMNMIQSTLAAAERVFEILDEEEEKPDPQDAVELEKVEGNIKFENVYFSYREDKKLIEDLNIEVRSGQTIAIVGPTGAGKTTLVNLLMRFYEIQGGSITIDGVDIRKLKRNNLRKFFGMVLQDTWLFNGTIRENIAYGKENATEEEIIRAAKLAHAHHFIMALPGGYDAMINEEASNISQGEKQLITIARAFVADPDILILDEATSNVDTLTEKYIQSAMKRLMHSRTNFVIAHRLSTIRDADMILVMNEGQIIEKGTHKQLMEKNGFYAELYKSQFLGAYV
>NZ_CP007389.1|WP_012056372.1|141341_143066_-|ABC-transporter-ATP-binding-protein
MRKLFKYLKKYSFLIFLTLFFVTIQAILNLYLPDLMADIVDKGVARGNVEYIWSVGWKMLGITLLNIAAAVISTFFAARIAMGFGKDLRSMLFKKVMNFSLNEVDKYGVSTLINRNTNDVTQIQNVMFMMLRIVALAPVTAIGGTIMAISKSPKLSMILLVSLPIMFVAMFFIVKYTIPLFKSMQKKLDKLNRVLRENLTGVRVIRAFAKTEYEKQRFEDANEDLTRTALKVNRVFALVFPIILLVMNITIVFLIWIGAIQVDKGALEVGNLMAVMQYIMQIMFSFIMISVIFIFLPRATASAERISQVLDEETKIKEIEIPKKLSNIEEIEFKDVVFYYEGGKEPAISNASFDIKKGEVVGIIGSSGSGKSTLVKLLMRFYDATSGKIYINGLDVKEFSQKTLRERISLTPSRPVIFSGTIEDNVRIGKKDATEEEIIEALKIAQAWEFVSKLPDGIKTKVSQGGTNLSGGQKQRLAIARAIVGKKDVYIFDDSFSALDFRTDAKLRRALREKLFDATKIIVSLRVATVMNADKIIVLENGKVVGIGTHKELMNTCTVYKEIVSSQLSEEEIA
>NZ_CP007389.1|WP_143610966.1|143049_143418_-|MarR-family-transcriptional-regulator
MEKYKLHPGQIPMFFIINKFPGITQKEIAEHMMVNTSTVAIMLKRLEKAGFVKKEIDENDRRYFHVYLTDKAKGIHDKLIKKVKEFEKMCFSGLSDLEMKELENLLKKIVNNLEAMKDEKTF
>NZ_CP007389.1|WP_012056374.1|143604_147528_+|alpha-2-macroglobulin
MKKILAILLIFVSAISFPYIWFYSTNVLIYPNRTVNFETDENFFVKVFRFDVSKEAVKGIFSNGGTQSEFSIKNIKKNFYSLELPDVPGIYYVIVNGKESIARQILFVTDLKAFIASTSNQFYFSVYDLRNKKFLEKLYYFDNYTTKTINGPIFSLNIEKYKDKVFFLKNNIVILSNYGGWSNYPERKTVVFTDKPIYKPGDTIHVRINALKKDNTKYIPYQTKLHVSLKDPFNNIVYKDTFETDTFGGIVFDYKTTEEIITGNYTLIISENDEILSRYYLLVQDYTKPTYTLSLTANATQLIVSDTLQVKLNAGYLNGDPVKNAEVLFYAFKGSHLINKTKAMTNENGKATYNIVTKEAGYYRIQALIVDDSGIQNEKNIYAMVKADNVDIKGAIDNETLKLRITNISGDPLNGIGVVNINEKEIYFEVKNGYAEIAIPKNTWWIEVKFGKEAKVIYKSFSVSNSGIIVANKNSVKPGEKIKVAIDPKDDIGVLVTGEEKIRKFNIITKKSEIELTIPIDEISSTYFIEFFGLKYNDRVKINVNHDRVKTLKIKLDKTQYKPGEIANIKFENSKSLKIVSVVDEGIYLLSNAKSVVNQLYPEINYPSYELYTSKTYVYFNRLSEFEKSKKSHIFASTKESEERRIREYFPETAYWNPSLMKNEISLKTPDSITKWRVTAYEISKNYIAEGIKTFVVTKPFEVKIFAPEFLVEGDKVIGEIYVKNYTGKIGKVDVKLNVNNGMVDFNSGRYKIEKELKIPFTLKDFKEGDLKITAEASMLSEYDGIKLTIPVKPIYISKDTSKVVKIAGKKVFDKDAKIRVINNLKDFLEPSIKALIHYPYGCVEQTMSSFYPVLVAKSFIEYPNLDDIILKGLQRLLKFQHTDGGWGWWTFDDSDLFMTSYVLEGLYYTKKLGFFVPEKVILDGLEYLKNQPIDGYAAFILNLYGEKNIDFKARNVVDYVYTDPDKIYEIATIGKDITYIKSNPSNHFYTSIHLTSIAVRTLTRYNKYLDLRDKMINYLLNSKKGPFWYSTKDTAFAILAIIESQKLNDYKSNIIFEAKDNKICVSGNGFVDVESTKKIYAQNQFNDINLKNRLYKKYDLLYDGKYLDVFLPVNTQFIPINMSKISTPTFSSEIPEEIARIIIDGTPVLFVNNKLLIEGPFKFVGNNYYFEKGYYEINFTKNYDYEIHKGDVLKTSIFIDGTGEYLVVEEYLPACAQVLKNYVERTPDYEGKFSYRWYSNEDIWYSYKDVKKDKIVYFIRYLHPGKLEYYWRVTSEGIFHKKPTYVYNMYYEDTFAIGSLYPFNIK
>NZ_CP007389.1|WP_143610970.1|147550_147949_+|hypothetical-protein
MCNFEIPYEVRNDLYKFLDEASLTLPTTPVSVYETTNLYEFNKTTGMPYSVGGIYKDFIIILQPRDVLIKKGVFYKVLTHELLHWVLYGLKEEYQEGLIYWWLKDYEKDEVDKFLDVFDGDLHKFIISNWKE
>NZ_CP007389.1|WP_143610968.1|147896_148529_+|DUF1175-family-protein
MFLMVIYTNLLFPIGKSDLKSLENLKLDVEDSMNFRLWFVAIALDNVDNEHPTFKTKDCSGFVFYCIKEALKKHDKDWFEKTGYKGPVFEDVKKYNYPNTPLGVNIFFNRKKYVSYVDAYNLLHYNTYFISYEKRYAKPGDLIFYFHPEDPEFPYHVMIYTGNGFVYHTGPEGEVRYVSYENMMLGDMAWKPIELNPAFLGYYGLKIHSN
>NZ_CP007389.1|WP_012056377.1|148570_149785_-|iron-containing-alcohol-dehydrogenase
MWESKVDIYNVFELRCKTTCYFGVGAINKVGDIFDTLKNQGIDNVIFVTDKVAYKVTGAWDVIKPELEKRGIKYVIYEDVSPNPTTTQINEATKLALENGAKAVIGIGGGSPIDAAKSVAVLLEYTDKTAEELYEGKFVPTKAKPIIAINTTHGTGTEVDRFAVASILEKEYKPAIAYDCIYPTFAIDDPQLMKTLPKNQTIFTAIDAINHVTEAATTLAASPYSILLAKETIRLISRYLPQAVAHPDDLTARYYLLYASAIAGISFDNGLLHFTHALEHPLSAVKPDLAHGLGLAILLPAVVKQIYVAKPEVLADIYNPIVPGLKGIPGEAEKIAVGIEKWLFSLGVTEKLENLGFVEKDIPKLTKLALETPSLGLLLSMAPIKADEKAISSIYRDSLTYISR
>NZ_CP007389.1|WP_012056378.1|149929_150448_+|hypothetical-protein
MKIQSFNFDFSYQRTFIKVKKSANVLIYEKKEKIKEKDLIKLIISKELLEKLTGKKFKLALPKIRYKIMVKIGKPEIEVYHEKFQLSFSKTTIEGKITTEDGKQISFSYFVDNLNLLYSKKDGLERIDFSLQNTNIKENLSIIFNNTEGSIISENKILGYVTPSEQNIDKKV
>NZ_CP007389.1|WP_012056379.1|150466_151801_-|SidA/IucD/PvdA-family-monooxygenase
MKVVIIGCTHAGTAAAINASKLYKDAEITIYERNDTISFLSCGIALHVGGVVKDPSKLFYSSPEHLKSLGINTKMRHNVKKVDFDEKTLLVEDLKSGEIFEDSFDKLIITTGSWPIIPNIEGIELNNILLSKNYYHAQEIIKRSENAKNVVVIGAGFIGVELAEAMKEKGKNVTLIDIESRILSKYLDEEFTKIAEDKLLKNGINLALNEKVTRFIGGKSVEKVITDKGEYNADLVILSVGFKPNTDLFKRKLDMLENGAIIVDEYMQTSRDDVFAAGDCSAVFYNPLKKYKYIPLATNAIRMGTIAAYNLNERRLRHLGTQGTSGIKIYDLNIAATGLTESMAKCNELEVDSVVITENHRPEFMPKFEKVMFKVVFGKDSKKILGAQILSKADLTQSINTMSVVIQNEMTIEELAFVDFFFQPHFNKPWNFLNMVGLEYLNRI

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Crispr_ID: NZ_CP007389_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007389_2

360035-360533

TypeI-B

Consensus_repeat	Method
GTTTTTACCTTACCTTGGAGGAATTGAAAT	PILER-CR
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CRISPRCasFinder
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CRT

7 spacers

cas2,cas1,cas4,cas3,cas5,cas7b,cas8b1,cas6

The CRISPR arrays of NZ_CP007389_2

>merge|NZ_CP007389|2|360035-360533|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATTCCTCCAAGGTAAGGTAAAAACAAAAAGCACTCAAAACGAGCGCCATATTTCGCCGTTAATTTCAATTCCTCCAAGGTAAGGTAAAAACGCAGGAATGGCTAATTGAAACCTTACTGTTCCATCAATTTCAATTCCTCCAAGGTAAGGTAAAAACACGAAAGCAATTCAGAAACTAACACAAATAGAGGCATTTCAATTCCTCCAAGGTAAGGTAAAAACCAAAATAACAATGATGGTTTGTTTAATTGTTTTGTTTCTATTTCAATTCCTCCAAGGTAAGGTAAAAACCAATATTCTTCCCAGCAATCTTGACAAAGCGCAAATTCATTTCAATTCCTCCAAGGTAAGGTAAAAACTTTCAAGTCACTACTTGATGCGGATCCAATATATATTATTTCAATTCCTCCAAGGTAAGGTAAAAACATTCAGCTGAGAACAATAGATACACACACACCAAATAATTTCAATTCCTCCAAGGTAAGGTAAAAAC

>NZ_CP007389|2|2|360035-360533|PILER-CR
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	AAAAAGCACTCAAAACGAGCGCCATATTTCGCCGTTA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	GCAGGAATGGCTAATTGAAACCTTACTGTTCCATCA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	ACGAAAGCAATTCAGAAACTAACACAAATAGAGGC
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CAAAATAACAATGATGGTTTGTTTAATTGTTTTGTTTCT
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CAATATTCTTCCCAGCAATCTTGACAAAGCGCAAATTC
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	TTTCAAGTCACTACTTGATGCGGATCCAATATATATT
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	ATTCAGCTGAGAACAATAGATACACACACACCAAATA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC

>NZ_CP007389|2|2|360035-360533|CRISPRCasFinder
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	AAAAAGCACTCAAAACGAGCGCCATATTTCGCCGTTA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	GCAGGAATGGCTAATTGAAACCTTACTGTTCCATCA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	ACGAAAGCAATTCAGAAACTAACACAAATAGAGGC
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CAAAATAACAATGATGGTTTGTTTAATTGTTTTGTTTCT
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CAATATTCTTCCCAGCAATCTTGACAAAGCGCAAATTC
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	TTTCAAGTCACTACTTGATGCGGATCCAATATATATT
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	ATTCAGCTGAGAACAATAGATACACACACACCAAATA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC

>NZ_CP007389|2|2|360035-360533|CRT
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	AAAAAGCACTCAAAACGAGCGCCATATTTCGCCGTTA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	GCAGGAATGGCTAATTGAAACCTTACTGTTCCATCA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	ACGAAAGCAATTCAGAAACTAACACAAATAGAGGC
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CAAAATAACAATGATGGTTTGTTTAATTGTTTTGTTTCT
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	CAATATTCTTCCCAGCAATCTTGACAAAGCGCAAATTC
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	TTTCAAGTCACTACTTGATGCGGATCCAATATATATT
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC	ATTCAGCTGAGAACAATAGATACACACACACCAAATA
ATTTCAATTCCTCCAAGGTAAGGTAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007389.1\|WP_012056579.1\|360969_361965_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP007389.1\|WP_012056582.1\|362897_364853_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP007389.1\|WP_012056570.1\|346239_347844_+\|DUF1957-domain-containing-protein	unknown	unknown	gnl\|CDD\|212104
NZ_CP007389.1\|WP_012056573.1\|348783_349962_+\|2-ketoisovalerate-ferredoxin-oxidoreductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181999
NZ_CP007389.1\|WP_012056580.1\|361970_362447_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP007389.1\|WP_012056575.1\|351059_351977_+\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133464
NZ_CP007389.1\|WP_012056576.1\|351966_352476_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227939
NZ_CP007389.1\|WP_012056574.1\|349975_350953_+\|thiamine-pyrophosphate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|239471
NZ_CP007389.1\|WP_012056585.1\|366541_368242_-\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	gnl\|CDD\|187822
NZ_CP007389.1\|WP_012056581.1\|362443_362836_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012056577.1\|357994_359677_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|214599
NZ_CP007389.1\|WP_012056569.1\|345451_346237_+\|DUF4912-domain-containing-protein	unknown	unknown	gnl\|CDD\|379808
NZ_CP007389.1\|WP_012056583.1\|364830_365592_-\|CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP007389.1\|WP_012056584.1\|365603_366527_-\|hypothetical-protein	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP007389.1\|WP_012056578.1\|360706_360967_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP007389.1\|WP_012056571.1\|347869_348445_+\|pyruvate-synthase	unknown	unknown	gnl\|CDD\|274014
NZ_CP007389.1\|WP_143610977.1\|369744_369942_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_041426154.1\|344496_345330_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|377015
NZ_CP007389.1\|WP_012056572.1\|348437_348770_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|224067
NZ_CP007389.1\|WP_012056586.1\|368253_368982_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499

Protein	Function_ID	Function_description	E-value
NZ_CP007389.1\|WP_012056579.1\|360969_361965_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.81258e-154
NZ_CP007389.1\|WP_012056582.1\|362897_364853_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.01743e-40
NZ_CP007389.1\|WP_012056570.1\|346239_347844_+\|DUF1957-domain-containing-protein	gnl\|CDD\|212104	cd10792, GH57N_AmyC_like, N-terminal catalytic domain of alpha-amylase ( AmyC ) and similar proteins. Alpha-amylases (alpha-1,4-glucan-4-glucanohydrolases, EC 3.2.1.1) play essential roles in alpha-glucan metabolism by catalyzing the hydrolysis of polysaccharides such as amylose starch, and beta-limit dextrin. This subfamily is represented by a novel alpha-amylase (AmyC) encoded by hyperthermophilic organism Thermotoga maritime ORF tm1438, and its prokaryotic homologs. AmyC functions as a homotetramer and shows thermostable amylolytic activity. It is strongly inhibited by acarbose. AmyC is composed of a N-terminal catalytic domain, containing a distorted TIM-barrel structure with a characteristic (beta/alpha)7 fold motif, and two additional less conserved domains. There are other two canonical alpha-amylases encoded from T. maritime that lack the sequence similarity to AmyC, and belong to a different superfamily.	0
NZ_CP007389.1\|WP_012056573.1\|348783_349962_+\|2-ketoisovalerate-ferredoxin-oxidoreductase-subunit-alpha	gnl\|CDD\|181999	PRK09622, porA, 2-oxoacid:ferredoxin oxidoreductase subunit alpha.	2.93079e-149
NZ_CP007389.1\|WP_012056580.1\|361970_362447_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.8223e-63
NZ_CP007389.1\|WP_012056575.1\|351059_351977_+\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133464	cd06854, GT_WbpL_WbcO_like, The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor. The WbcO/WbpL substrate specificity has not yet been determined, but the structure of their biosynthetic end products implies that UDP-N-acetyl-D-fucosamine (UDP-FucNAc) and/or UDPN-acetyl-D-quinosamine (UDP-QuiNAc) are used. The subgroup of bacterial UDP-HexNAc:polyprenol-P HexNAc-1-P transferases includes the WbcO protein from Yersinia enterocolitica and the WbpL protein from Pseudomonas aeruginosa. These transferases initiate LPS O-antigen biosynthesis. Similar to other GlcNAc/MurNAc-1-P transferase family members, WbpL is a highly hydrophobic protein possessing 11 predicted transmembrane segments.	3.43815e-37
NZ_CP007389.1\|WP_012056576.1\|351966_352476_+\|hypothetical-protein	gnl\|CDD\|227939	COG5652, COG5652, Predicted integral membrane protein [Function unknown].	7.05384e-13
NZ_CP007389.1\|WP_012056574.1\|349975_350953_+\|thiamine-pyrophosphate-binding-domain-containing-protein	gnl\|CDD\|239471	cd03376, TPP_PFOR_porB_like, Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea and some hyperthermophilic bacteria. PFOR catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA, a crucial step in many metabolic pathways. Archaea, anaerobic bacteria and eukaryotes that lack mitochondria (and therefore pyruvate dehydrogenase) use PFOR to oxidatively decarboxylate pyruvate, with ferredoxin or flavodoxin as the electron acceptor. The 36-kDa porB subunit contains the binding sites for the cofactors, TPP and a divalent metal cation, which are required for activity.	6.32167e-133
NZ_CP007389.1\|WP_012056585.1\|366541_368242_-\|hypothetical-protein	gnl\|CDD\|187822	cd09691, Cas8b_I-B, CRISPR/Cas system-associated protein Cas8b. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-B subtype; also known as Csh1 family.	0.00358819
NZ_CP007389.1\|WP_012056577.1\|357994_359677_-\|HAMP-domain-containing-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	5.08333e-53
NZ_CP007389.1\|WP_012056569.1\|345451_346237_+\|DUF4912-domain-containing-protein	gnl\|CDD\|379808	pfam16258, DUF4912, Domain of unknown function (DUF4912). This family consists of uncharacterized proteins around 160 residues in length and is mainly found in various Clostridium species. The function of this family is unknown.	4.30764e-54
NZ_CP007389.1\|WP_012056583.1\|364830_365592_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.99718e-17
NZ_CP007389.1\|WP_012056584.1\|365603_366527_-\|hypothetical-protein	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.35094e-26
NZ_CP007389.1\|WP_012056578.1\|360706_360967_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.03544e-27
NZ_CP007389.1\|WP_012056571.1\|347869_348445_+\|pyruvate-synthase	gnl\|CDD\|274014	TIGR02175, Pyruvate_synthase_subunit_PorC, 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. A number of anaerobic and microaerophilic species lack pyruvate dehydrogenase and have instead a four subunit, oxygen-sensitive pyruvate oxidoreductase, with either ferredoxins or flavodoxins (H. pylori) used as the acceptor. Several related four-subunit enzymes may exist in the same species. This model describes the gamma subunit. In Pyrococcus furious, enzymes active on pyruvate and 2-ketoisovalerate share a common gamma subunit.	6.21967e-75
NZ_CP007389.1\|WP_041426154.1\|344496_345330_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|377015	pfam03313, SDH_alpha, Serine dehydratase alpha chain. L-serine dehydratase (EC:4.2.1.13) is a found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyzes the deamination of serine to form pyruvate. This enzyme is part of the gluconeogenesis pathway.	5.29147e-79
NZ_CP007389.1\|WP_012056572.1\|348437_348770_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|224067	COG1144, COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit [Energy production and conversion].	8.95038e-28
NZ_CP007389.1\|WP_012056586.1\|368253_368982_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	5.80942e-27

>NZ_CP007389.1|WP_012056577.1|357994_359677_-|HAMP-domain-containing-protein
MRQRILFKLVTPIIILASLIIVIFITTYVITTSQKFDALIVNLAGRQRMLTQKMSKEALIVSHGEVSYKEKLTKTLKLFEITLYALRDGGKTYTDLTMKTPVKISPAGTEKIKKQLNVVEKLFLPFKDVIQQRILNSNGKDPEAIKYIIDNNEKLLSEMNAAVLLFQNFAERKVKWMKHIQGWLAITGLGIVVGFIILYWNVIYKPLKQLLQVSQELARGEADLSKRIPVITKDELGKIADSFNRFMEVIKNVAVSIMKNTDEVASSTSALKNFLNIVGDKSENIREVTDKFTEDLQQVNEIVNQMDANVQEVAKSAVSVAEAATELSENMNEILEEADSGMNIIKEVNESIDVVNSETSEMAKKSELLEKSVNAIGEILNVISGVAEQTNLLALNAAIEAARAGEAGKGFAVVADEIRKLAEETKKSADEIAVKLGDISHRSKETANSSREMVASINRVLEKMEDMSKKFITIRENVENAARKAEDLAAVSQEQSASAEEMASSIKEISGLVEDTSNHMVETNKAINEQSEQVISAKNKIDYISDIVAKLRESVRGFKV
>NZ_CP007389.1|WP_012056576.1|351966_352476_+|hypothetical-protein
MVIDVKKRMFLVFLIVVWVLTIFYFSSRTPVESSQQSNLVTKILKKIDSIIDFSNTKLFKNIELFMKKLWFRTQYVPAEMLVRKTAHFGLYFILGFLTYLLFQKYGIIISTIIGISLPNLIATIDEYTQQYYNRGSSLNDVIIDLSGTISGVLFGIVLVLIFKLFLKKK
>NZ_CP007389.1|WP_012056575.1|351059_351977_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MIYSFLLSFIFTIVTIPFLRKIAFKFNIIDYPDKNLKNHEKATPYLGGMAFMGAFLLFTPFSLFRKLYVFILGILGLYDDIKSLNPWIRITLEFVIGYLVAIRFLDNPFKVLIATIFYAFLTNSVNMMDGMDGICATTSLIATVGLIFTVAYPNDKYYLIALIGTLLGFIIFNFPPAKIFMGDLGSYTIGGILGIAIISSFSKSFDHTIASLIILAPFFIDTFSSMFRRILHEKSPFSGDREHIYDKIFRITKDKRKTLLFTAVISTIFCSLGMFYLKSKVFSIIFSIILIIFLILKLKLLKYGD
>NZ_CP007389.1|WP_012056574.1|349975_350953_+|thiamine-pyrophosphate-binding-domain-containing-protein
MAFNIMQLATKFADKNPGITQGHRLCPGCAAPNVAKFALMTAQAMGYEPIVGFATGCMEVSTTIYPYTAWNIPYIHNAFENAAATVSGIETAYRALLKKGRLVDPNKKYAFFAFGGDGGTYDIGLQSLSGAVERGHKFIYIVYDNEGYMNTGNQRSGATPPGSQTTTQPVGKKLPGKIQLKKNIVEIMAGHENVYVATVSTSEPMDFFKKIEKALEFDGPSFIAAISPCVRFWRVNDDKAVEISKLAVETGYWPLYEVERGVYRVTKKVKELKPVKEFIEKQGRFRNLLKRPDADEIINELQEYIKRRWERLLALEEATKDKPIR
>NZ_CP007389.1|WP_012056573.1|348783_349962_+|2-ketoisovalerate-ferredoxin-oxidoreductase-subunit-alpha
MPEIKNRQAVTGAQAIANAMRQINPDVVAAYPITPQTPVVEYFAQYVADGLADTEMIPVESEHSAMSAVVGAAAAGARAMTATAANGLALMHEIVYIAASSRLPIVMPVANRALSGPINIHCDHSDAMAERDSGWIQLWAENAQEAYDFTIMAVRLAEHEDVRLPVMVNFDGFIISHGVEVVDFLDDEVVKKFVGEPKVIYPLLDVEKPVTHGPLDLYDYYFEHKRQQIEAMKHVKKVFKEIAEEFEKISGRKYDVLDKYKIDDAEYIMIALGSTAGTVKYTVDLLREEGHKVGVIKPQIFRPFPKTELQELLNGRKAVIVLDRAASFGAEAPLYEAVKSALYEVAVRPQLGSYVYGLGGRDIKVEHIKKAFEDAFSGNLIVDEERYLGLRE
>NZ_CP007389.1|WP_012056572.1|348437_348770_+|4Fe-4S-dicluster-domain-containing-protein
MAELKGWKDIPIGGVIDRPATAKEYQTGTWRVIRPVHQPENCIHCMMCWLYCPDQAIVIEVVDGKPKMKGYNYYYCKGCGLCANVCPKTNDKLPEEKRAIVMKPETEFQD
>NZ_CP007389.1|WP_012056571.1|347869_348445_+|pyruvate-synthase
MPAKYFEIRWHARAGQGAKSASQMLAEAALEMGKYVQSFPEYGAERTGAPMKAFNRVSDEPILIHSSVDYPDVVVIIDDTMLGQPALTDGTDENTVFIVNTVKDVEYVREKLGVKGKICTIAATDIALEELKRGIPNTVMLGAIAKVTGVITLESAEQRIRKAFSKKFPEELVEANVRALRRGFEEVKCNG
>NZ_CP007389.1|WP_012056570.1|346239_347844_+|DUF1957-domain-containing-protein
MPKGNVVMVLHAHLPYVHHPDYDFFLEENWLFEAITETYVPLIRMFKRLENENTKFNLTMSITPPLMEMLANKDLQEKYIKRMTKLIELAKKEVERTKNEHPKKHKMAKFYLEDFKEILYIFKDVYKGNILNAFKEFLEKGKLDIITCNATHGFLPFMEQYPQAIRAQLEQAIKTYERHLGRKPRGIWLAESAYFSGLDKYLKEYGLEYFFVDSHGLWYADERPKYGVYRPVITPNNVFVFARDPESSEQVWSAQIGYPGDGRYREFYRDIGFDREFEYIKPYIDPSGVRTNTGIKYHKITSKNVNLNEKDFYDIDDAKSTAKEHAIDFLKKKEQQATKLLNLFKGLEPIIVAPFDAELFGHWWFEGPIFLEEFMRAASKSKKIRTLKAYDVVDMIEKIQIVTPATSTWGANGYNEVWLNGTNDWIYPHLHEAIEKMTEVANMYPNPEKNPKEINEALNQMARELMLAQSSDWAFIMTTRTSVDYAVNRTKTHLKRFLDLYNMVISGKIDMRRVSHYVWLDDIFPDIDYTMYKV
>NZ_CP007389.1|WP_012056569.1|345451_346237_+|DUF4912-domain-containing-protein
MFDENVEKLKEWLSEKRTIQELKAMAKNLGLKVKRMMKKKEVIKLLESYIKQNEEIKKLERPSSSTSASDSIKKEDKLSKEELYLPKSYNKNKLVLMPVNPNWLHAYWDYTKETFETLNKLPKEYRIVLRIYDVTFIEFTGNNAHRTFEIRITPNMRNYYINVPIPNADYLAEIGYITPDGNFYSLIRSNVCKTPPNSPSNSTREKWLDLRKKRKIVTPSDGVLVKEVETIPGSIFKIEEIQNKSEQIWELFSKLRSGRGI
>NZ_CP007389.1|WP_041426154.1|344496_345330_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MANSMPLHEVILTVEMLENGYDPNDTKQKISKILKTILEESKKQYGQKQKTLTGLTGDNAYKFKNYKPKLMGNFNYVATVTALSISESNAAMGRIAACPTAGSSGIIPGAFYALHVIFNPPYEKLLNSFIVSGGIGNIISKKAPLSGAAGGCQAEIGSAAAMAAGGLAYFFSENPEIVGNAAALALKSLMGLVCDPVGGFVEVPCVKRNGNIVNLAISSAELALSGIKSTIPLDEVIDAMYKVGKSLPESLRETGEGGIAATKTAVDLVRNIVKNLH
>NZ_CP007389.1|WP_012056578.1|360706_360967_-|CRISPR-associated-endonuclease-Cas2
MFVILYYDVNKKRVSKMLKTCRKYLTWVQNSVFEGEISISNLERLKIELENIIKDEDSVVIYTFKQMFYSKREVLGKDKKEETKFI
>NZ_CP007389.1|WP_012056579.1|360969_361965_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKETVYIFSDGTLKREDNSLVFLTKDNVKKHIPVENLKEIYIFGEVNCNKRLLEFVAKKEIMISFFNYYGFYVGSFYPREHYNSGFMILKQAEHYIDKEKRLFIAKKFVEGAVKNSLKVLKYYNRRGKQLINHIHEIEESLKETNLVCNIPKLMQIEGRIKKIYYNAFNNIIESEDFNFLKRSKRPPIDRINALISFSNSLIYSIVLREIYSTHLDPRIGFLHSTNFRRFSLNLDIAEIFKPVLGDRVIFSAINKEVIGVKDFEKSLNRVFLNNNGKKKIIEMLENKLKETVKMKKIGKKVSYRTLIRMELYKLEKHFLDDEIYTSLVMEW
>NZ_CP007389.1|WP_012056580.1|361970_362447_-|CRISPR-associated-protein-Cas4
MITGSLIQAYIVCRRQAWLLSRQLVGDQDNDFIVIGRLISKESYKNSKKEIVIDGGKIDIVKKERGFLKLVEVKKSSKMIKSAKFQLLFYMWKLNVYYGEIRIPKEKKVIEVEMTDDNEKQLLTIVNELEETINNPKMPKPERKSYCSTCSFEYFCWS
>NZ_CP007389.1|WP_012056581.1|362443_362836_-|hypothetical-protein
MNLIEGYSFSLFVPISIPVKKIKNMKNLLFKFKLIDKDDEFLDGKKVWDIFRNNDFNYVEHRLFSKIFSNFVVSLFNYRIEGKGIKEILKDEMFGEFYYAEDYSKYYSYDCGLNVEKFLKLKSSREYDFI
>NZ_CP007389.1|WP_012056582.1|362897_364853_-|CRISPR-associated-helicase/endonuclease-Cas3
MKLFMFSKNIDNKMAHKNGMYFETFYEHVEKTEKYLERIIDKFDLERILGNLFSEIGIDSSHIQTIKEIIKYHDIGKLTDEFQEGLIKGKIKVTHSDVGFYTIATLLTDKLLSENLKKDEFLFLFFLSTVVSRHHSVLFDIDKVITWNENKEKFVKDILENIETINDKGEIVKKTKQVFEKIKQLKIYKKIEFYILYKLINSLLITSDYLATLEFMKGVEISINAIDKTLKKAILENISSRNIEGNFNPYIDENFDRLKAMKKENISDINTLRSVMAARVEEKFKNSNKKVFFIEIPTGGGKTNISLRLISRLLENKKKVFYVIPFINIIEQNFEYFSKFIPKEHITRYDHKYLNVTDDENKEKTFTQMLFLNFPFVFSTHVGFFDMFFRNGKSDNFNFYQLANSVVVLDEVQAYNPKFWNTLSNLFYYLSKYLNTTIIIMSATLPDFTKFVDKGSFVEDLSPDVVEHKIFNRVNTLFLKENHTFEEKVLEEINESKKVLIVVNTVKKSYEIYENLEDKINGEIYLLNSTLLDIRKKELIDYIKSYDKEKPLILVSTQSIEAGVDLDFDVGFRAFSILDSIIQTMGRVNRNARLSRATLYLFDDGMWKKIYGSDVRKKILEENFSKFKNGSLTLKDFYMLTIENLKKKINK
>NZ_CP007389.1|WP_012056583.1|364830_365592_-|CRISPR-associated-protein-Cas5
MKAFSFELKGDMGFFKKNDTNATVYATYNFIHKLNLFGIFGAILGLEGYKRDKSGNFMEYYEKFKNFKVAITPLYNKPPKKTLVIFNNSTGHASREAGGVLQIKEQVIVESIGYRIFIPCLETFTDEEKNVYEKLEKMVKKNYSEYPIYFGKNEFLAYFENYCSIELERLEFEESTVNSLVRLKDIEFFKENLDDIELFEEETDYISILEELPYDFNENHLYLKDVFVFTNKKLRLKRKENFWRTNNEVIYVF
>NZ_CP007389.1|WP_012056584.1|365603_366527_-|hypothetical-protein
MFTKRCYGIVVLKSENSNWNADFTKYPRRLPDENATIFATDKSAKYAIRKFFLDSGEKVFVWRTFKEDGKPRSLDETDKYWQEVLKDEIKWIIQKKKNKNGKEEEIKNIDRYDFFNKFIDVKLFGITFAVGESQMSITGPFQISYGINRYNVNIPFVVDIASPFRNKEGDKQTTLGDEIKNLKSYYVYDFVLNPKNLPDGMELTDDDISKLKEALKKFATNLNTTSKIGTENALLLFITLKENSKLVLPTMKNLVDVNKDEIIDLTKISNLLENYGNEIENVEVYYNDSICKVAGIKDNWEKGDILL
>NZ_CP007389.1|WP_012056585.1|366541_368242_-|hypothetical-protein
MINQMIEFSKELRDSRFYDLLEEKAQDLVYVIIPPEDKKKFYFVLDEKYYDKVNLLENARKIDDVNDDLREILKNVKVLTAKLPGDEKGNKSIKGNKGTNSYNLFIFQGPKPKNGDFTKKIMLVYNSETLKSFKNRVKEDLLEKLIFKGDEAKFLYEKVNDMSLKVFNKEYEEIYKNIYFVFELENKELYKDFHQKYLKEKVFAVENVKEYGICPICGKKDIISIPGVFHTLNVKKPFLKHLGRKTEYNIMICKDCAFELTTFLEKFLKKFSIFPLLSKKKLRELEIKFLKSSGEKLSFREILEQVFKEVDVNDLILDFYLIIYKDDFVYVDYVSNFRYYYNETNIFEIENYLDKMFDNFLVKNYFGSITIKNNLLAKNIYKYRENIFDFIYRARYDSLSKETIDNIFYDSLVCYLKGLYSEEKNFLKKIEKAFESYKKLNKIFGGDFMEKTEKVETEDLEKIEDSYQYYYLLGKLTRFLLSQSKISNKTHALVEPFINVNSSKVMLERIYELFTKYKHAINFYNEKFDKIFGLILNYFNSGKLPEKVSKNDKFYFFEGYFSSRKL
>NZ_CP007389.1|WP_012056586.1|368253_368982_-|CRISPR-associated-endoribonuclease-Cas6
MRIKVGFISIEDIILPVGFNKYIQALIYNLFSNSLRRFVHEEGFRSKRKFSLFCFSSILEKGQYFKRMKVFNFGKNISFYISSPVTKLMENLVLNLLNGDKYFLGENDIYLSSVEVVYKEIAKDILKVNALTPIEVHQTYKENGRNKTKYFAPFEREFSKLINLNLKSKWEAFYKENLDRDIEIISLGNMNKSVVYYGFGDKKYVVEGWKGKFLLKGEPSVLAFAYDAGLGSKNSQGFGFIE
>NZ_CP007389.1|WP_143610977.1|369744_369942_-|hypothetical-protein
MKVGMTPAKVELLTGSELAKDRPWFVGIFESMNYAISRLRIENYVFILERCPLLERLFKQLSYFC

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Crispr_ID: NZ_CP007389_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007389_3

754395-758275

Orphan

Consensus_repeat	Method
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CRISPRCasFinder
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CRT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	PILER-CR

55 spacers

The CRISPR arrays of NZ_CP007389_3

>merge|NZ_CP007389|3|754395-758275|CRISPRCasFinder,CRT,PILER-CR
TTTTCCATTCCTCATAGGTAGATTCTAAACTAACATTGCAATATTGCGACGATACTGGATATGAAATGTAATTTCCATTCCTCATAGGTAGATTCTAAACATCTCATATCCAAGCATATGGTTCAAGACAAGGCCTCAATTTCTATTCCTCATAGGTAGATTCTAAACACGCAATCGTGGATCAACTTGAAAAAGCCAAATATTACATTTCTATTCCTCATAGGTAGATTCTAAACGAAACAATAAACGTTGCCAACAAAACGTGGCAAAAAGTTAATTTCTATTCCTCATAGGTAGATTCTAAACTCAATTATTTTTGATGAAGAATGGCCTGCGGGTATTTTTAATTTCTATTCCTCATAGGTAGATTCTAAACTTGCCGCCACGGTGGCTGAGGCAACAGTGGCTGCCAAAATTTCTATTCCTCATAGGTAGATTCTAAACAACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAAATTTCTATTCCTCATAGGTAGATTCTAAACGAAATATGTATTTGGAATATTTATGATAGGGTGCAGGACAGATTTCTATTCCTCATAGGTAGATTCTAAACGTAGTCCCCCCCTCTGAGGGAGAAATCATTTTCGTCGATTTCTATTCCTCATAGGTAGATTCTAAACATTAATAAATTGGATGAGGAAGACCTAATCAAACTTGTACATTTCTATTCCTCATAGGTAGATTCTAAACTATACTTACCGCTAAACGCAGATTTAGATCAAATAAAAGATTTCTATTCCTCATAGGTAGATTCTAAACTTCTTAGTTTTGAAGATTTTGAAGGGAGTAAAGTTTAATTTCTATTCCTCATAGGTAGATTCTAAACTTGGTGAATATGTAAATATATATTTCAGGAAGATTGATAGATTTCTATTCCTCATAGGTAGATTCTAAACAAAATGTATTTTAAATTTTTATAAATTTTATCCATCACAGAATTCAAATTTCTATTCCTCATAGGTAGATTCTAAACAAAAGTATTATGGAATAGGACTTTATGAAGATTTAATATTTCTATTCCTCATAGGTAGATTCTAAACGACGAATTTTGGACTAATGGCTGGGATGCTGAAAAAACTGCATTTCTATTCCTCATAGGTAGATTCTAAACCTATTTGAACGCATTGTCAAGAGAGTACATCAACTAAAATCTATTTCTATTCCTCATAGGTAGATTCTAAACTTTTTTAGCGCGCTTGGTGTATAACTTACCAATGTCGCATTTCTATTCCTCATAGGTAGATTCTAAACACAAAAAATTATCAGGTATGATTCAGGCAACCAAAAACAAAATTTCTATTCCTCATAGGTAGATTCTAAACAAAGTCCTCTTCTTTTTTTACTTAACAATGGAATCGTTTCATTTCTATTCCTCATAGGTAGATTCTAAACAAAACAATTACCAATTGAAATATGGAACGATGATGAAACAAACATTTCTATTCCTCATAGGTAGATTCTAAACAACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAAATTTCTATTCCTCATAGGTAGATTCTAAACAGGATCATGTAGAAGAATTAAAACGTAGCATCGAAGAGGTTGATTTCTATTCCTCATAGGTAGATTCTAAACGGTATTTTTGAGGTTCAAGAGTATCGTTTGAGCGACAATTTAAATTTCTATTCCTCATAGGTAGATTCTAAACGACAAAACAAGAAAAGAAGGTGTTGAAAGGGTTGCGAGAAATTTCTATTCCTCATAGGTAGATTCTAAACGAAGCAATACAAACCGGAATCGTAACGCCATATACCGATTTCTATTCCTCATAGGTAGATTCTAAACTACCCATCAACACACAAGTTTGGGAACGATATCTTGATTTCTATTCCTCATAGGTAGATTCTAAACCATATACAATATATGCGAAATCAGATGGTGCATTACCAATAATTTCTATTCCTCATAGGTAGATTCTAAACTTCAAGTGCAAAGACTGGGTGATTGTATTGAAATTTCTTATTTCTATTCCTCATAGGTAGATTCTAAACGAACATTTTAGGCGCATTTGTTTCTAAGTATTTTAGAGGATTTCTATTCCTCATAGGTAGATTCTAAACTTAAAAACCCCTAACATTGGCAATTTATCAGGTAATGGTGTAACTAATTTCTATTCCTCATAGGTAGATTCTAAACTATATATTTTATAATTGTGTGGGTTCTGGATATGGACAAATACATTTCTATTCCTCATAGGTAGATTCTAAACGAAAGCATGGAGGTTGAAACAAAAATTTTTGGCGGGGGTGATTTCTATTCCTCATAGGTAGATTCTAAACGAGAATTATCAGAAGAAGTAATGGTGGACTTGCATGATATTGAATTTCTATTCCTCATAGGTAGATTCTAAACATTGATCCAGAAACTGGCGATAAAATTGGCGAGACGTATTTCTATTCCTCATAGGTAGATTCTAAACAACCTTGCAAAACGGGAAGGTCAATCTGACCTTCCAAATGGATTTCTATTCCTCATAGGTAGATTCTAAACTGTATTTCAAGAGGATTGATATAGAATTGTTGAAATCCTTATTTCTATTCCTCATAGGTAGATTCTAAACCGATGATAGCGGTCATGGCAGAGCAGTATTGACTTATTTCTATTCCTCATAGGTAGATTCTAAACGAATTAAGAAAATTTGCAGGGTCACTCGGGGTGTGACCCTGATTTCTATTCCTCATAGGTAGATTCTAAACATATTAAACTGCTAGTCCTCGCAATAATAGGGGACCATTTCTATTCCTCATAGGTAGATTCTAAACCATTAGACACAATTTTGAATGTCGCACTTGAAAAGCTTGCAGATTTCTATTCCTCATAGGTAGATTCTAAACTGATATTTTTTAGTTTTGAGGATTTTGTTAGAAGTAAAGTTTATATTTCTATTCCTCATAGGTAGATTCTAAACTGTTTTATATTGTCAAAAAAGGGGCTATAATCGAACCCCCATTTCTATTCCTCATAGGTAGATTCTAAACAACCAGGAAGCGGCGGGAAGGTGCCATGGCCTGTCGTGTAATTTCTATTCCTCATAGGTAGATTCTAAACGGATTATATTGTAGAAAAATTAACAGTTGTTGACTTGTATATTTCTATTCCTCATAGGTAGATTCTAAACAGAAATAATTGATTTACATGAGGAGGTGGGGTATTATGTTATTTCTATTCCTCATAGGTAGATTCTAAACTATTTTTTAATTATGAGGATTTTGTTAGAAGTAAAGTTTAATTTCTATTCCTCATAGGTAGATTCTAAACGGGGATTTCGGTGACAGTTACGATTTGTTTTATATTGTCAATTTCTATTCCTCATAGGTAGATTCTAAACAAACAAAACATGCAAGATATTTGGTATTTACTGAAACACAATTTCTATTCCTCATAGGTAGATTCTAAACGTATTTTAAATTTTTATAAATTTTATGCTTCGCAATTTCTATTCCTCATAGGTAGATTCTAAACCATATAATAGCATTTAGCAATGTATTTTTACGAATACTACAACATTTCTATTCCTCATAGGTAGATTCTAAACGAGTTTTATTCCCCTACCTCAAGCGGTGCTTGGGTAGGGGTAAAATTTCTATTCCTCATAGGTAGATTCTAAACCTTATTTAAAACATTAAAAGAAGAAGCACAAGAATCTGAACAATTTCTATTCCTCATAGGTAGATTCTAAACTTATTTTGGTTGATCACAGAAAGCCCTTTGCTGAAATTATATTTCTATTCCTCATAGGTAGATTCTAAACTTTTTATTGCGGCGACGTGCCCTTTCGAAGCAAGACTAATTTCTATTCCTCATAGGTAGATTCTAAAC

>NZ_CP007389|3|3|754395-758275|CRISPRCasFinder
TTTTCCATTCCTCATAGGTAGATTCTAAAC	TAACATTGCAATATTGCGACGATACTGGATATGAAATGTA
ATTTCCATTCCTCATAGGTAGATTCTAAAC	ATCTCATATCCAAGCATATGGTTCAAGACAAGGCCTCA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ACGCAATCGTGGATCAACTTGAAAAAGCCAAATATTAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAACAATAAACGTTGCCAACAAAACGTGGCAAAAAGTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TCAATTATTTTTGATGAAGAATGGCCTGCGGGTATTTTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTGCCGCCACGGTGGCTGAGGCAACAGTGGCTGCCAAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAATATGTATTTGGAATATTTATGATAGGGTGCAGGACAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GTAGTCCCCCCCTCTGAGGGAGAAATCATTTTCGTCG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ATTAATAAATTGGATGAGGAAGACCTAATCAAACTTGTAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TATACTTACCGCTAAACGCAGATTTAGATCAAATAAAAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTCTTAGTTTTGAAGATTTTGAAGGGAGTAAAGTTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTGGTGAATATGTAAATATATATTTCAGGAAGATTGATAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAATGTATTTTAAATTTTTATAAATTTTATCCATCACAGAATTCAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAAGTATTATGGAATAGGACTTTATGAAGATTTAAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GACGAATTTTGGACTAATGGCTGGGATGCTGAAAAAACTGC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CTATTTGAACGCATTGTCAAGAGAGTACATCAACTAAAATCT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTTTTTAGCGCGCTTGGTGTATAACTTACCAATGTCGC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ACAAAAAATTATCAGGTATGATTCAGGCAACCAAAAACAAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAGTCCTCTTCTTTTTTTACTTAACAATGGAATCGTTTC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAACAATTACCAATTGAAATATGGAACGATGATGAAACAAAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AGGATCATGTAGAAGAATTAAAACGTAGCATCGAAGAGGTTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GGTATTTTTGAGGTTCAAGAGTATCGTTTGAGCGACAATTTAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GACAAAACAAGAAAAGAAGGTGTTGAAAGGGTTGCGAGAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAGCAATACAAACCGGAATCGTAACGCCATATACCG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TACCCATCAACACACAAGTTTGGGAACGATATCTTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CATATACAATATATGCGAAATCAGATGGTGCATTACCAATA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTCAAGTGCAAAGACTGGGTGATTGTATTGAAATTTCTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAACATTTTAGGCGCATTTGTTTCTAAGTATTTTAGAGG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTAAAAACCCCTAACATTGGCAATTTATCAGGTAATGGTGTAACTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TATATATTTTATAATTGTGTGGGTTCTGGATATGGACAAATAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAAGCATGGAGGTTGAAACAAAAATTTTTGGCGGGGGTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAGAATTATCAGAAGAAGTAATGGTGGACTTGCATGATATTGA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ATTGATCCAGAAACTGGCGATAAAATTGGCGAGACGT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACCTTGCAAAACGGGAAGGTCAATCTGACCTTCCAAATGG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TGTATTTCAAGAGGATTGATATAGAATTGTTGAAATCCTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CGATGATAGCGGTCATGGCAGAGCAGTATTGACTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAATTAAGAAAATTTGCAGGGTCACTCGGGGTGTGACCCTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ATATTAAACTGCTAGTCCTCGCAATAATAGGGGACC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CATTAGACACAATTTTGAATGTCGCACTTGAAAAGCTTGCAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TGATATTTTTTAGTTTTGAGGATTTTGTTAGAAGTAAAGTTTAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TGTTTTATATTGTCAAAAAAGGGGCTATAATCGAACCCCC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACCAGGAAGCGGCGGGAAGGTGCCATGGCCTGTCGTGTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GGATTATATTGTAGAAAAATTAACAGTTGTTGACTTGTAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AGAAATAATTGATTTACATGAGGAGGTGGGGTATTATGTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TATTTTTTAATTATGAGGATTTTGTTAGAAGTAAAGTTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GGGGATTTCGGTGACAGTTACGATTTGTTTTATATTGTCA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAACAAAACATGCAAGATATTTGGTATTTACTGAAACACA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GTATTTTAAATTTTTATAAATTTTATGCTTCGCA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CATATAATAGCATTTAGCAATGTATTTTTACGAATACTACAAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAGTTTTATTCCCCTACCTCAAGCGGTGCTTGGGTAGGGGTAAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CTTATTTAAAACATTAAAAGAAGAAGCACAAGAATCTGAACA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTATTTTGGTTGATCACAGAAAGCCCTTTGCTGAAATTAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTTTTATTGCGGCGACGTGCCCTTTCGAAGCAAGACTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC

>NZ_CP007389|3|3|754395-758275|CRT
TTTTCCATTCCTCATAGGTAGATTCTAAAC	TAACATTGCAATATTGCGACGATACTGGATATGAAATGTA
ATTTCCATTCCTCATAGGTAGATTCTAAAC	ATCTCATATCCAAGCATATGGTTCAAGACAAGGCCTCA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ACGCAATCGTGGATCAACTTGAAAAAGCCAAATATTAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAACAATAAACGTTGCCAACAAAACGTGGCAAAAAGTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TCAATTATTTTTGATGAAGAATGGCCTGCGGGTATTTTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTGCCGCCACGGTGGCTGAGGCAACAGTGGCTGCCAAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAATATGTATTTGGAATATTTATGATAGGGTGCAGGACAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GTAGTCCCCCCCTCTGAGGGAGAAATCATTTTCGTCG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ATTAATAAATTGGATGAGGAAGACCTAATCAAACTTGTAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TATACTTACCGCTAAACGCAGATTTAGATCAAATAAAAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTCTTAGTTTTGAAGATTTTGAAGGGAGTAAAGTTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTGGTGAATATGTAAATATATATTTCAGGAAGATTGATAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAATGTATTTTAAATTTTTATAAATTTTATCCATCACAGAATTCAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAAGTATTATGGAATAGGACTTTATGAAGATTTAAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GACGAATTTTGGACTAATGGCTGGGATGCTGAAAAAACTGC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CTATTTGAACGCATTGTCAAGAGAGTACATCAACTAAAATCT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTTTTTAGCGCGCTTGGTGTATAACTTACCAATGTCGC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ACAAAAAATTATCAGGTATGATTCAGGCAACCAAAAACAAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAGTCCTCTTCTTTTTTTACTTAACAATGGAATCGTTTC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAAACAATTACCAATTGAAATATGGAACGATGATGAAACAAAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AGGATCATGTAGAAGAATTAAAACGTAGCATCGAAGAGGTTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GGTATTTTTGAGGTTCAAGAGTATCGTTTGAGCGACAATTTAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GACAAAACAAGAAAAGAAGGTGTTGAAAGGGTTGCGAGAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAGCAATACAAACCGGAATCGTAACGCCATATACCG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TACCCATCAACACACAAGTTTGGGAACGATATCTTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CATATACAATATATGCGAAATCAGATGGTGCATTACCAATA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTCAAGTGCAAAGACTGGGTGATTGTATTGAAATTTCTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAACATTTTAGGCGCATTTGTTTCTAAGTATTTTAGAGG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTAAAAACCCCTAACATTGGCAATTTATCAGGTAATGGTGTAACTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TATATATTTTATAATTGTGTGGGTTCTGGATATGGACAAATAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAAAGCATGGAGGTTGAAACAAAAATTTTTGGCGGGGGTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAGAATTATCAGAAGAAGTAATGGTGGACTTGCATGATATTGA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ATTGATCCAGAAACTGGCGATAAAATTGGCGAGACGT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACCTTGCAAAACGGGAAGGTCAATCTGACCTTCCAAATGG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TGTATTTCAAGAGGATTGATATAGAATTGTTGAAATCCTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CGATGATAGCGGTCATGGCAGAGCAGTATTGACTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAATTAAGAAAATTTGCAGGGTCACTCGGGGTGTGACCCTG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	ATATTAAACTGCTAGTCCTCGCAATAATAGGGGACC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CATTAGACACAATTTTGAATGTCGCACTTGAAAAGCTTGCAG
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TGATATTTTTTAGTTTTGAGGATTTTGTTAGAAGTAAAGTTTAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TGTTTTATATTGTCAAAAAAGGGGCTATAATCGAACCCCC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AACCAGGAAGCGGCGGGAAGGTGCCATGGCCTGTCGTGTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GGATTATATTGTAGAAAAATTAACAGTTGTTGACTTGTAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AGAAATAATTGATTTACATGAGGAGGTGGGGTATTATGTT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TATTTTTTAATTATGAGGATTTTGTTAGAAGTAAAGTTTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GGGGATTTCGGTGACAGTTACGATTTGTTTTATATTGTCA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	AAACAAAACATGCAAGATATTTGGTATTTACTGAAACACA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GTATTTTAAATTTTTATAAATTTTATGCTTCGCA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CATATAATAGCATTTAGCAATGTATTTTTACGAATACTACAAC
ATTTCTATTCCTCATAGGTAGATTCTAAAC	GAGTTTTATTCCCCTACCTCAAGCGGTGCTTGGGTAGGGGTAAA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	CTTATTTAAAACATTAAAAGAAGAAGCACAAGAATCTGAACA
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTATTTTGGTTGATCACAGAAAGCCCTTTGCTGAAATTAT
ATTTCTATTCCTCATAGGTAGATTCTAAAC	TTTTTATTGCGGCGACGTGCCCTTTCGAAGCAAGACTA
ATTTCTATTCCTCATAGGTAGATTCTAAAC

>NZ_CP007389|3|3|754396-758275|PILER-CR
TTTCCATTCCTCATAGGTAGATTCTAAACT	AACATTGCAATATTGCGACGATACTGGATATGAAATGTAA
TTTCCATTCCTCATAGGTAGATTCTAAACA	TCTCATATCCAAGCATATGGTTCAAGACAAGGCCTCAA
TTTCTATTCCTCATAGGTAGATTCTAAACA	CGCAATCGTGGATCAACTTGAAAAAGCCAAATATTACA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AAACAATAAACGTTGCCAACAAAACGTGGCAAAAAGTTAA
TTTCTATTCCTCATAGGTAGATTCTAAACT	CAATTATTTTTGATGAAGAATGGCCTGCGGGTATTTTTAA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TGCCGCCACGGTGGCTGAGGCAACAGTGGCTGCCAAAA
TTTCTATTCCTCATAGGTAGATTCTAAACA	ACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAAA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AAATATGTATTTGGAATATTTATGATAGGGTGCAGGACAGA
TTTCTATTCCTCATAGGTAGATTCTAAACG	TAGTCCCCCCCTCTGAGGGAGAAATCATTTTCGTCGA
TTTCTATTCCTCATAGGTAGATTCTAAACA	TTAATAAATTGGATGAGGAAGACCTAATCAAACTTGTACA
TTTCTATTCCTCATAGGTAGATTCTAAACT	ATACTTACCGCTAAACGCAGATTTAGATCAAATAAAAGA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TCTTAGTTTTGAAGATTTTGAAGGGAGTAAAGTTTAA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TGGTGAATATGTAAATATATATTTCAGGAAGATTGATAGA
TTTCTATTCCTCATAGGTAGATTCTAAACA	AAATGTATTTTAAATTTTTATAAATTTTATCCATCACAGAATTCAAA
TTTCTATTCCTCATAGGTAGATTCTAAACA	AAAGTATTATGGAATAGGACTTTATGAAGATTTAATA
TTTCTATTCCTCATAGGTAGATTCTAAACG	ACGAATTTTGGACTAATGGCTGGGATGCTGAAAAAACTGCA
TTTCTATTCCTCATAGGTAGATTCTAAACC	TATTTGAACGCATTGTCAAGAGAGTACATCAACTAAAATCTA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TTTTTAGCGCGCTTGGTGTATAACTTACCAATGTCGCA
TTTCTATTCCTCATAGGTAGATTCTAAACA	CAAAAAATTATCAGGTATGATTCAGGCAACCAAAAACAAAA
TTTCTATTCCTCATAGGTAGATTCTAAACA	AAGTCCTCTTCTTTTTTTACTTAACAATGGAATCGTTTCA
TTTCTATTCCTCATAGGTAGATTCTAAACA	AAACAATTACCAATTGAAATATGGAACGATGATGAAACAAACA
TTTCTATTCCTCATAGGTAGATTCTAAACA	ACGAATTGTTGGGGTTCCTGGTTTTGTAAGATAAATAAA
TTTCTATTCCTCATAGGTAGATTCTAAACA	GGATCATGTAGAAGAATTAAAACGTAGCATCGAAGAGGTTGA
TTTCTATTCCTCATAGGTAGATTCTAAACG	GTATTTTTGAGGTTCAAGAGTATCGTTTGAGCGACAATTTAAA
TTTCTATTCCTCATAGGTAGATTCTAAACG	ACAAAACAAGAAAAGAAGGTGTTGAAAGGGTTGCGAGAAA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AAGCAATACAAACCGGAATCGTAACGCCATATACCGA
TTTCTATTCCTCATAGGTAGATTCTAAACT	ACCCATCAACACACAAGTTTGGGAACGATATCTTGA
TTTCTATTCCTCATAGGTAGATTCTAAACC	ATATACAATATATGCGAAATCAGATGGTGCATTACCAATAA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TCAAGTGCAAAGACTGGGTGATTGTATTGAAATTTCTTA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AACATTTTAGGCGCATTTGTTTCTAAGTATTTTAGAGGA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TAAAAACCCCTAACATTGGCAATTTATCAGGTAATGGTGTAACTAA
TTTCTATTCCTCATAGGTAGATTCTAAACT	ATATATTTTATAATTGTGTGGGTTCTGGATATGGACAAATACA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AAAGCATGGAGGTTGAAACAAAAATTTTTGGCGGGGGTGA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AGAATTATCAGAAGAAGTAATGGTGGACTTGCATGATATTGAA
TTTCTATTCCTCATAGGTAGATTCTAAACA	TTGATCCAGAAACTGGCGATAAAATTGGCGAGACGTA
TTTCTATTCCTCATAGGTAGATTCTAAACA	ACCTTGCAAAACGGGAAGGTCAATCTGACCTTCCAAATGGA
TTTCTATTCCTCATAGGTAGATTCTAAACT	GTATTTCAAGAGGATTGATATAGAATTGTTGAAATCCTTA
TTTCTATTCCTCATAGGTAGATTCTAAACC	GATGATAGCGGTCATGGCAGAGCAGTATTGACTTA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AATTAAGAAAATTTGCAGGGTCACTCGGGGTGTGACCCTGA
TTTCTATTCCTCATAGGTAGATTCTAAACA	TATTAAACTGCTAGTCCTCGCAATAATAGGGGACCA
TTTCTATTCCTCATAGGTAGATTCTAAACC	ATTAGACACAATTTTGAATGTCGCACTTGAAAAGCTTGCAGA
TTTCTATTCCTCATAGGTAGATTCTAAACT	GATATTTTTTAGTTTTGAGGATTTTGTTAGAAGTAAAGTTTATA
TTTCTATTCCTCATAGGTAGATTCTAAACT	GTTTTATATTGTCAAAAAAGGGGCTATAATCGAACCCCCA
TTTCTATTCCTCATAGGTAGATTCTAAACA	ACCAGGAAGCGGCGGGAAGGTGCCATGGCCTGTCGTGTAA
TTTCTATTCCTCATAGGTAGATTCTAAACG	GATTATATTGTAGAAAAATTAACAGTTGTTGACTTGTATA
TTTCTATTCCTCATAGGTAGATTCTAAACA	GAAATAATTGATTTACATGAGGAGGTGGGGTATTATGTTA
TTTCTATTCCTCATAGGTAGATTCTAAACT	ATTTTTTAATTATGAGGATTTTGTTAGAAGTAAAGTTTAA
TTTCTATTCCTCATAGGTAGATTCTAAACG	GGGATTTCGGTGACAGTTACGATTTGTTTTATATTGTCAA
TTTCTATTCCTCATAGGTAGATTCTAAACA	AACAAAACATGCAAGATATTTGGTATTTACTGAAACACAA
TTTCTATTCCTCATAGGTAGATTCTAAACG	TATTTTAAATTTTTATAAATTTTATGCTTCGCAA
TTTCTATTCCTCATAGGTAGATTCTAAACC	ATATAATAGCATTTAGCAATGTATTTTTACGAATACTACAACA
TTTCTATTCCTCATAGGTAGATTCTAAACG	AGTTTTATTCCCCTACCTCAAGCGGTGCTTGGGTAGGGGTAAAA
TTTCTATTCCTCATAGGTAGATTCTAAACC	TTATTTAAAACATTAAAAGAAGAAGCACAAGAATCTGAACAA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TATTTTGGTTGATCACAGAAAGCCCTTTGCTGAAATTATA
TTTCTATTCCTCATAGGTAGATTCTAAACT	TTTTATTGCGGCGACGTGCCCTTTCGAAGCAAGACTAA
TTTCTATTCCTCATAGGTAGATTCTAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007389.1\|WP_012056956.1\|769787_770705_-\|5,10-methylenetetrahydrofolate-reductase	unknown	unknown	gnl\|CDD\|273212
NZ_CP007389.1\|WP_012056940.1\|750394_751108_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP007389.1\|WP_012056955.1\|769242_769779_-\|methionine-synthase	unknown	unknown	unknown
NZ_CP007389.1\|WP_077277077.1\|759352_761053_-\|DUF2207-domain-containing-protein	unknown	unknown	gnl\|CDD\|378333
NZ_CP007389.1\|WP_012056950.1\|762176_763433_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|237087
NZ_CP007389.1\|WP_012056945.1\|758777_759329_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|377192
NZ_CP007389.1\|WP_012056934.1\|746103_747051_+\|porphobilinogen-synthase	unknown	unknown	gnl\|CDD\|236450
NZ_CP007389.1\|WP_012056938.1\|749446_749728_+\|energy-coupling-factor-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|179494
NZ_CP007389.1\|WP_012056943.1\|752445_753987_-\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP007389.1\|WP_012056953.1\|766365_766914_-\|NADH-oxidase	unknown	unknown	gnl\|CDD\|380320
NZ_CP007389.1\|WP_012056939.1\|749717_750398_+\|cobalt-transporter	unknown	unknown	gnl\|CDD\|274139
NZ_CP007389.1\|WP_041425969.1\|770706_771405_-\|UPF0280-family-protein	unknown	unknown	gnl\|CDD\|235284
NZ_CP007389.1\|WP_012056936.1\|747471_748743_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607
NZ_CP007389.1\|WP_143611063.1\|751754_752288_-\|reverse-transcriptase-like-protein	unknown	unknown	gnl\|CDD\|260009
NZ_CP007389.1\|WP_012056935.1\|747032_747479_+\|bifunctional-precorrin-2-dehydrogenase/sirohydrochlorin-ferrochelatase	unknown	unknown	gnl\|CDD\|224562
NZ_CP007389.1\|WP_012056941.1\|751104_751737_+\|diphthine--ammonia-ligase	unknown	unknown	gnl\|CDD\|238952
NZ_CP007389.1\|WP_041425967.1\|766918_769240_-\|homocysteine-methyltransferase	unknown	unknown	gnl\|CDD\|273959
NZ_CP007389.1\|WP_012056951.1\|763661_764582_-\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|223383
NZ_CP007389.1\|WP_012056952.1\|764705_766241_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012056937.1\|748739_749447_+\|energy-coupling-factor-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|181384

Protein	Function_ID	Function_description	E-value
NZ_CP007389.1\|WP_012056956.1\|769787_770705_-\|5,10-methylenetetrahydrofolate-reductase	gnl\|CDD\|273212	TIGR00676, 510-methylenetetrahydrofolate_reductase., 5,10-methylenetetrahydrofolate reductase, prokaryotic form. The enzyme activities methylenetetrahydrofolate reductase (EC 1.5.1.20) and 5,10-methylenetetrahydrofolate reductase (FADH) (EC 1.7.99.5) differ in that 1.5.1.20 (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while 1.7.99.5 (assigned in many bacteria) is flexible with respect to the acceptor; both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as 1.5.1.20 and 1.7.99.5, this model describes the subset of proteins found in bacteria, and currently designated 1.7.99.5. This protein is an FAD-containing flavoprotein. [Amino acid biosynthesis, Aspartate family].	1.65158e-94
NZ_CP007389.1\|WP_012056940.1\|750394_751108_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	3.48889e-81
NZ_CP007389.1\|WP_077277077.1\|759352_761053_-\|DUF2207-domain-containing-protein	gnl\|CDD\|378333	pfam09972, DUF2207, Predicted membrane protein (DUF2207). This domain, found in various hypothetical bacterial proteins, has no known function.	1.36505e-99
NZ_CP007389.1\|WP_012056950.1\|762176_763433_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|237087	PRK12391, PRK12391, TrpB-like pyridoxal phosphate-dependent enzyme.	0
NZ_CP007389.1\|WP_012056945.1\|758777_759329_-\|LemA-family-protein	gnl\|CDD\|377192	pfam04011, LemA, LemA family. The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.	1.97491e-86
NZ_CP007389.1\|WP_012056934.1\|746103_747051_+\|porphobilinogen-synthase	gnl\|CDD\|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NZ_CP007389.1\|WP_012056938.1\|749446_749728_+\|energy-coupling-factor-ABC-transporter-substrate-binding-protein	gnl\|CDD\|179494	PRK02898, PRK02898, energy-coupling factor ABC transporter substrate-binding protein.	4.57162e-45
NZ_CP007389.1\|WP_012056943.1\|752445_753987_-\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP007389.1\|WP_012056953.1\|766365_766914_-\|NADH-oxidase	gnl\|CDD\|380320	cd02144, iodotyrosine_dehalogenase, iodotyrosine dehalogenase. Iodotyrosine dehalogenase catalyzes the removal of iodine from the 3, 5 positions of L-tyosine in thyroid, liver and kidney, using NADPH as electron donor. This enzyme is a homolog of the nitroreductase family. These enzymes are usually homodimers.	4.51531e-71
NZ_CP007389.1\|WP_012056939.1\|749717_750398_+\|cobalt-transporter	gnl\|CDD\|274139	TIGR02454, Uncharacterized_protein_MJ1089, cobalt ECF transporter T component CbiQ. This model represents the CbiQ component of the cobalt-specific ECF-type. CbiQ is now recognized as the T component of energy-coupling factor (ECF)-type transporters. The S component confers specificity (CbiM-N for cobalt systems), which CbiO is the ABC-family ATPase. In general, proteins found by this model reside next to the other putative subunits of the complex, identified as CbiN, CbiO, or CbiM. Note that the designation of cobalt transporter has been spread excessively among ECF system transporters with many other specificities. [Transport and binding proteins, Cations and iron carrying compounds].	4.01191e-17
NZ_CP007389.1\|WP_041425969.1\|770706_771405_-\|UPF0280-family-protein	gnl\|CDD\|235284	PRK04334, PRK04334, hypothetical protein; Provisional.	2.87479e-56
NZ_CP007389.1\|WP_012056936.1\|747471_748743_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
NZ_CP007389.1\|WP_143611063.1\|751754_752288_-\|reverse-transcriptase-like-protein	gnl\|CDD\|260009	cd09277, RNase_HI_bacteria_like, Bacterial RNase HI containing a hybrid binding domain (HBD) at the N-terminus. Ribonuclease H (RNase H) enzymes are divided into two major families, Type 1 and Type 2, based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, Type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD) residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Prokaryotic RNase H varies greatly in domain structures and substrate specificities. Prokaryotes and some single-cell eukaryotes do not require RNase H for viability. Some bacteria distinguished from other bacterial RNase HI in the presence of a hybrid binding domain (HBD) at the N-terminus which is commonly present at the N-termini of eukaryotic RNase HI. It has been reported that this domain is required for dimerization and processivity of RNase HI upon binding to RNA-DNA hybrids.	4.6002e-56
NZ_CP007389.1\|WP_012056935.1\|747032_747479_+\|bifunctional-precorrin-2-dehydrogenase/sirohydrochlorin-ferrochelatase	gnl\|CDD\|224562	COG1648, CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism].	6.16646e-45
NZ_CP007389.1\|WP_012056941.1\|751104_751737_+\|diphthine--ammonia-ligase	gnl\|CDD\|238952	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins is predicted to bind ATP. This domainhas a strongly conserved motif SGGKD at the N terminus.	9.41244e-55
NZ_CP007389.1\|WP_041425967.1\|766918_769240_-\|homocysteine-methyltransferase	gnl\|CDD\|273959	TIGR02082, Methionine_synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase. This family represents 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), one of at least three different enzymes able to convert homocysteine to methionine by transferring a methyl group on to the sulfur atom. It is also called the vitamin B12(or cobalamine)-dependent methionine synthase. Other methionine synthases include 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (MetE, EC 2.1.1.14, the cobalamin-independent methionine synthase) and betaine-homocysteine methyltransferase. [Amino acid biosynthesis, Aspartate family].	4.98838e-132
NZ_CP007389.1\|WP_012056951.1\|763661_764582_-\|inorganic-phosphate-transporter	gnl\|CDD\|223383	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism].	6.57676e-55
NZ_CP007389.1\|WP_012056937.1\|748739_749447_+\|energy-coupling-factor-ABC-transporter-permease	gnl\|CDD\|181384	PRK08319, PRK08319, energy-coupling factor ABC transporter permease.	2.5487e-119

>NZ_CP007389.1|WP_012056943.1|752445_753987_-|glutamine-hydrolyzing-GMP-synthase
MKTVVVLDYGSQYTQLIVRRVREKGYYAELLPWDAKEEEVKRLNPTAIILSGGPSSVYEKDAPFVPEYVLHLNIPILGICYGLQALVHKFGGRVEKSQKREFGHAILEVEEDPLFEGLPKKFDVWMSHSDRVEKLPEGFYVIGRSENSPFAAIRNKNETIYGVQFHPEVTHTQFGSKILENFVSKIAKMEKNWEMKDFVSEKIKEIKGIVGNDKVILGLSGGVDSSVVAMLLHKAIGDNLVPVFVDTGLLRLNEGEEVKENFERLGIKIFVVDAKKRFLDALKDVEDPEEKRKIIGHTFIDVFYETSMQLLEEFGNIKYLAQGTLYPDIIESKVSERKSAAKIKTHHNVGGLPEKLPFKIIEPLRYLFKDEVRKIGEILELPQSMINRHPFPGPGLAVRIIGKVTEEAISILQKADYIFIEELKKNNLYDKVWQAFAVFLPIKSVGVMGDYRTYENVIALRAVNSFDGMTADWSKLPHEFLNKVAKRIINEVKGVNRVVYDITSKPPATIEWE
>NZ_CP007389.1|WP_143611063.1|751754_752288_-|reverse-transcriptase-like-protein
MKLQLFYNKTDKITSLVILKAENKEIVEKFVNYFKCLEIYVDGSYSHEFKRASFGVVILSKNIEKYYMVINKFLKHRNVTGEILGVIYALSYAYENGYGCVKLYYDYEGIEKWVVGEWKAKTELTKMYKEKVLEYGKYINIKFEKVRAHTGDKYNEQADKLAKYAIKTNSSNVEFEI
>NZ_CP007389.1|WP_012056941.1|751104_751737_+|diphthine--ammonia-ligase
MKTFCSWSGGKDSTLALYHGLKKFKVDYLFTMLSEDGIHSRAHGLPKSILEKQANSIGIPLITKCSTWGEYEKNFLDFLEEYAKGGMGIFGDIDLQEHLDWVENVCNKKNVRVFEPLWRRNRREIVEEFLKLGFKAKIIAVKKDLNIEKYLGKDLSFDLISEFESIGIDACGENGEFHTFVYNGPIFKNPVDFEIGTCVEKSKNLVLEIK
>NZ_CP007389.1|WP_012056940.1|750394_751108_+|ABC-transporter-ATP-binding-protein
MIELKNISFGYDKEYVLENVTLCFPKNKKIAILGNNGCGKTTLLLICSGLLKPKKGKIYLDNTLVKNKELRKKVGIVFQNPDTQLLPVKVYQDISFGLFNLGYEKSFVEKRVKEIIKEFEMESLKDKPTQFLSYGQKKLVSIADIVALNPEYILLDEPDSYLDYKSFIRIQKILDKLLKKGKTIVISTHNSDFAYQWADYVYIIDNKKVILEGNPSFVFSKKDILEKTNLKIPGGVL
>NZ_CP007389.1|WP_012056939.1|749717_750398_+|cobalt-transporter
MIIEKISYTNSFSNYHPFPKILFSLSLLFLTFWFSPIINLITVFTVISLLLYTKVPPKKLFNIFLGVFLFIFLTSIALFFDFSEITPERGTSVFLRSCAGVSSILFLVLTTPVFELISLIPNRTIKDMLFLIYRAIYILLNITNEIILSQNSRYGYSTPKNTINSLKYLTYGIFNKALYFSKESEKGLISRFYSNNISILNRFNTKKDISLIFIAEMFLIYLEVII
>NZ_CP007389.1|WP_012056938.1|749446_749728_+|energy-coupling-factor-ABC-transporter-substrate-binding-protein
MSKKHIILLSICIILVIFSLLINGGAEFSGADGQAEELIGTIAKDYSPWFSPIWEPPSGEIESLLFSLQAALGAIFIGYYFGYMKGRKVKNDN
>NZ_CP007389.1|WP_012056937.1|748739_749447_+|energy-coupling-factor-ABC-transporter-permease
MRYLKFFLLLVFLVPSFGFSMHIMEGFLPPTHALIWYILSLPFFVIGLFTIRKTIKEKPNLKMLLAFVGAFTFVLSAMKIPSVTGSCSHPTGIGLGAIIFGPFTMTVIGTIVLLFQALLLAHGGLTTLGANTFSMAIVGSLVSYFIYKSLYKKNRNIAVFLAAFLGDLFTYVTTSFQLAVAFPDKTHGFIFSLAKFLSIFAITQVPLAIIEGLVTVVVIDLIYKYNKNELFEEGL
>NZ_CP007389.1|WP_012056936.1|747471_748743_+|glutamate-1-semialdehyde-2,1-aminomutase
MFEKAKEFMPGGVNSPVRAFKSVELDPIFVKSAKGSKIKDINNNEYIDYIQSWGALILGHSHEVVINAINEQSQKGTSYGLCHPLEVEMAQILVENIPSIEMVRMVNSGTEAVMSAIRLARAYTKRDFIVKFEGCYHGHSDSLLVKAGSGALTFGTPNSEGVTKEFVSKTIVAKYNDVQNINEIFENFGDKIACVIVEPIAGNMGVVPPKPNFLLTLRKLTKKYNSILIFDEVITGFRVSQNGAQGLFNVIPDLTTLGKVIGGGLPVGAFGGKKEIMQLISPQGPVYQAGTLSGNPLTLAAGVSTLKFILNNKNFYKKLDELAKTLEEGLLYALKDFNIKVNRVGSMISFFFNGSSVDTYEKVISSDVNMYKKLFKYFLSYGILLPPSPFESLFISYAHTNEDIQQTIDIAMKFSKNLKEGKV
>NZ_CP007389.1|WP_012056935.1|747032_747479_+|bifunctional-precorrin-2-dehydrogenase/sirohydrochlorin-ferrochelatase
MAFIPIMLNLTGKKCLVIGGGKVAARKLKYFVNKADVTVIAKNISKEIKNTKGVMYIEKEYSPGDLEGFDVVIITTNDKKLNEKIHHEAKKKKILTNNATSKIFCEFIMPAIIEYKGYTISISTNGENPKKVKQLKEKIKKFLEGLDV
>NZ_CP007389.1|WP_012056934.1|746103_747051_+|porphobilinogen-synthase
MKRLRRLRNNETIRSLIRETHLTTNDLIYPLFIKDGYKIKEEIPSMPEIFRLSIDMAIDEIKTLRNLGINAFLLFGVPNKKDLKCINIVNKALEEIKSEIKDAYLITDVCLCSYTEDGHCGITKDGIILNDESVELLSEISLSYAQSGADMIAPSDMMDGRVKKIRKTLDKNNFSDIPIMSYSAKFASSFYGPFRDAANSAPKFGDRKTYQLDIANKNEALREIALDIEEGADIVMIKPALSFLDIVEATKRTFNIPVAVYNVSGEYSMVKAAAQKGWIDEKEVVLETLTSMKRAGADIIITYHAKDVAKWLSYQ
>NZ_CP007389.1|WP_012056945.1|758777_759329_-|LemA-family-protein
MIGYIVLAIVLLFVLYLIGTYNSLVRLKKLIENAWSQIDVQLKRRHDLIPNLVNSVKGYMKYEQETLEKVMKARAAAISSKDINKRMESENELTGLLSRLLAVVENYPELKANENVNQLMNELRKTEDKIAYARQFYNDTVMKYNTKISVFPSNVVAKMFNFKGEPFFKIKETEKEVPTVSFE
>NZ_CP007389.1|WP_077277077.1|759352_761053_-|DUF2207-domain-containing-protein
MFLFSLVYFVFFVFVTGYFDDFFKVYKISSANVEQVMDSNGILHVHEIITFDMKKPFRGVYREVPASRAVEIENVKLWIENVEGEWVELEKDNKSFKARVWVSKTPISPEKVDKLILHVTYDAKYAIEKGKDISQVFRQFWGNEWDSTVGKLTAKFIFPKEANIVKVYVHPKVDVEKIGNSYTVSINNHPKRSFAEARFLIDNFSPKYLYRNPTLTLNEVEEIEKKYSLRHTLSLILPPISIILVILLLVLTFYYFGREKDIQYHGIYERKIPYKDTPDIVNAIVVNQLKKIDKDGISAVIMDLYKKGYLELDKEGKYIKVLEKEGDLPLTERYFYEFLKKYSTNSLFSFSELKKTLSKDKSLAKEFLGDFGAYKSTVLDEAKSRGYLSLMGTYISYVLASFSIVLAIAYFILFSSVTFKYQLFFSGVLFVLGGVVFLLDRDVFGSWSKEGREYYVKWNKFKEFLLDFSALSKYPPDSIILWEEYLVYATALGIADEVEKHMKKLVPKEISDDSIYYYPYRRFGSQFFAVSYVATSAVSSSSNGGGFSGGAGGVGGGSGGGGGGAF
>NZ_CP007389.1|WP_012056950.1|762176_763433_-|TrpB-like-pyridoxal-phosphate-dependent-enzyme
MRVIYLSTEEMPRHWYNVLSDLPFELDPPLDPETTNPISPEKLLKIFPEPLLEQEMTKKRFIEIPDEVLKEYLRFRPTPLIRAKFLEEYLDTPAKIFYKYEGVSPTGSHKTNTAIAQVYYNRISGTKVLYTETGAGQWGSALSYAGLKFNIPVKVFMVRVSFEQKPMRKQLMNLFGGDVVPSPSKFTEFGKSFDENHPGSLGIAISEAMEKVLNEEGAKYSLGSVLNHVLLHQTVIGLEIKKQLEKVNLEPDVIIACHGGGSNFGGTVFPFVPDKLSGKNVDFVACEPESCPTLTKGVYRYDFGDSSGLTPLLKMYTLGKDFIPPKIHAGGLRYHGASPIISRLVKEEIIRAESFSQDETFNAARIFAKVEGIVPAPESAHAIAGAIREAKRAKEEKREKVIVFTLSGHGLFDLSAYS
>NZ_CP007389.1|WP_012056951.1|763661_764582_-|inorganic-phosphate-transporter
MYILPAILFGVFLGSNDSANIFGPSVEMGILRYRLITVVSAISIFFGAIFGGKSGIETISSFSNMNIYFAVLSTISAVLTMVILSKLGIPSSSSQAIVGGILGAGILNNYVNIGILFKLLVAWVLTPIGGMFFGFLMYKVLSVPFNKIRSIQLREKLIVLFTLVIGAYASFSLGANNVANVTGVFAKKMGIDTAVFIGGLSISVGALFSNKRVMYTISKRIIELDYFSSAISVLGQAITVWLYSLVGIPVSVSQAIVGAVIGAGFAKGSKLVNKRIIVKIALTWIVTPTFSAFFTILLYYITNFFD
>NZ_CP007389.1|WP_012056952.1|764705_766241_-|hypothetical-protein
MKKFLWILVVVLIFLTFFGCVGNFFNDISLESKVEDLDSVTEDNPAYVAAVVVDDETQSLIEDVMMVFSGSMSTYSSFSLNSKSDSYETYDKDEFEIIEAILDVLEKHKGAIDKIRKVMTITEKVRQRDDRYNFKIVFEGEARDKILSVFPHAAVTSTDEVALDYRDLMLIRVSAKTLINAYDKRKNIRSMVRDARKVKNSMENIDIPFISDDASSLIVDFISKNPSPLLETYWQNLKILADSLAGLKPDVNILDMKDIFIEDAFVTPGFSKEIDFASVTLDSLIEIYEFEKLKADEKGWTSWYSLYELYQLKSLATRSENIFVAKELLDEKILEELPESMTLKLNSFEVGSETKIYDVLKVINESLPDKTLTIDFSYEEKIDGITSSSSETVFVTGKFTVDFSKLSAETIDWKENNIGIQKIFFQSFIENQIWNLDSTNAKEKIKNIIYDFFESQTLITRSDNKLNLKLELEPVKYEFSISFETLSIDEFIDVLIDLLAGELSNLLFSAP
>NZ_CP007389.1|WP_012056953.1|766365_766914_-|NADH-oxidase
MLLELAKKRKTVRIFSDKKPDIEDIKYAINVAKEAPSGMNAQPWHFKIVDAQKEKEKIREIVEKEERKFYESSKGKLKEFLKNANITWKKEFLTQAPYLLFVYSDKSAPFSKESTWLAIGYLLLALEEIGLSTVTYTPPNLNDFSFGNYKLEVILPIGYGNDPKEKYHRKNIDEIISFNDIF
>NZ_CP007389.1|WP_041425967.1|766918_769240_-|homocysteine-methyltransferase
MERKEFLELLNERIYFLDGAYGTEFFKLGFKEVIETLNVTNSEMVYALQKAYVDAGVDFLLTNTFSANRLKLSSLKVKYNLKDINYNAVKIAKKARKDKKVYILGDISSTGYLISPLGELTFDEAYEVFKEQGEILLNSGIDGFILETMSDLKELKAAILALRDLSKDVPIIVQMTFDEDGVAVTGTSVEIFSTLMNDLDVDVVGINCTLEPEKLLPVFKQLSNYSRKPISVEPNAGKPKLLRDGSIVYNTSPEKFALYMEDFVEFGANIVGGCCGTSPEHIRLMVEFLKEKKPKKREIVKEEFVSSRTKLKKMKPFLIIGERINAAGKKKFQQKIRERNYNKIVELAILQEKEGAHVLDLNLGIEKLLDKTHFSQVVNTLDKISSLPLSLDIQEFEFMEMALKEYVGRPIINSSTAKRENLDKAIYLLKRYGGILILLTMKDKIPESAKERFDIALEAIRYLEKHDIEKERVIVDPLVLPLGAKKDPAVTIKTIELLSKEGINTSIGLSNLSFGMPNREALNSSFLALCIDKGLTAAILNTSEKCTMNAVFGSLTLKGVDFEKKEIIRNEPMIEMILNKKEDELKREIEKLLEEYTPLQISQDILSKKMEYIGELYSKGEIYLPQLILAAETVTPIFEYLNSLIESNAREKLGTVVLATVEGDVHDIGKRIVGTVLKSSGINVIDLGKDVPAKEILKAVKEYKPDIVGLSAMMTTTIGRIKEVKDLFVDNNVDIPIISGGASMNKEIADNFGVYYAKNASQALKLVKKILKR
>NZ_CP007389.1|WP_012056955.1|769242_769779_-|methionine-synthase
MVYIPEKHEYMPSKKIFLARAGMRYKGMENDLNEEINEIYLEGLRLSKPIVWFDTIKDIPNFVPKSFKGIKKITIFVSTLGKDIDEKIEEYMENGEIFKGAILDAWASEALEKLNDSFDKKLREKMGKGTMRFSPGYGDVDIRKNKDIINFLKIKEIKVLQSGVMIPRKTTTCMVGWW
>NZ_CP007389.1|WP_012056956.1|769787_770705_-|5,10-methylenetetrahydrofolate-reductase
MKISKIKDFFVSVEVIPPLRGHSIDEIYKVVDKIAPFNPAFISVTKHPAELEYYEVDGRILKLPKVRRPGTMGIVAALKMRYDIDVVPHLTCIGNSKFELEELLIDLDFIGIDNVFVVRGDKKRNVIKKDGQYEYAYQLVEQIFNMNKGKYLYQNAKKTDFCIGVAGYPEKHFESPNMTEDIKYLKRKIEAGAKFVITQMFFDEKKYIDFVERLKKENITIPIIPGIKPITSYKSAKKLPGTFFIDIPEKLLEDLREAKTEKEEFFVGIRHTIKMIEKLREYGIPGIHIFTMSKPDPVLEILKNI
>NZ_CP007389.1|WP_041425969.1|770706_771405_-|UPF0280-family-protein
MNRYYRELMGHNLFSFRVKYKESDIWIGMDKKIPGLPILIYEYLVDLRKSIEEYVDEEFLGVLKPLKIKCDEPEIVKDMILCSQKAGVGPMAAVAGAFSKFVGRFILNTFSPQKLFVENGGDLYVFSTTDTSVGIVSNTINLKIELPAGEYGIATSSRYIGHSKNFGKTDTTTVVTHDATLSDAYATAISNNIKNVYDAKRILKKEFQEIQDIVVIIDGYVVIKGIHRVRGW

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Crispr_ID: NZ_CP007389_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007389_4

866811-866894

TypeI-A

Consensus_repeat	Method
TTTAATTCTTTTTTTATTTCTTCA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP007389_4

>merge|NZ_CP007389|4|866811-866894|CRISPRCasFinder
TTTAATTCTTTTTTTATTTCTTCAACTTTTTTTCCTTCTAGTACATTAACTTTTTTCTTTTTTAATTCTTTTTTTATTTCTTCA

>NZ_CP007389|4|4|866811-866894|CRISPRCasFinder
TTTAATTCTTTTTTTATTTCTTCA	ACTTTTTTTCCTTCTAGTACATTAACTTTTTTCTTT
TTTAATTCTTTTTTTATTTCTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007389.1\|WP_041425982.1\|873619_874051_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057041.1\|859675_860596_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP007389.1\|WP_012057042.1\|860592_861402_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP007389.1\|WP_012057051.1\|869709_869973_-\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP007389.1\|WP_012057038.1\|856820_857894_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340891
NZ_CP007389.1\|WP_012057049.1\|868299_868536_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|379063
NZ_CP007389.1\|WP_012057039.1\|857896_858202_-\|rubrerythrin	unknown	unknown	gnl\|CDD\|275328
NZ_CP007389.1\|WP_012057045.1\|862998_864093_-\|DUF445-family-protein	unknown	unknown	gnl\|CDD\|377281
NZ_CP007389.1\|WP_012057055.1\|874062_874356_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057056.1\|874640_875453_+\|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455
NZ_CP007389.1\|WP_143611012.1\|854323_854929_-\|glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|172882
NZ_CP007389.1\|WP_012057052.1\|870081_871419_+\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240539
NZ_CP007389.1\|WP_012057037.1\|855753_856818_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|376768
NZ_CP007389.1\|WP_012057054.1\|873154_873559_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057053.1\|871415_873149_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP007389.1\|WP_012057050.1\|868547_869633_-\|permease	unknown	unknown	gnl\|CDD\|281730
NZ_CP007389.1\|WP_012057036.1\|854925_855726_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057048.1\|867583_868255_-\|DNA/RNA-nuclease-SfsA	unknown	unknown	gnl\|CDD\|224406
NZ_CP007389.1\|WP_012057046.1\|864112_865987_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NZ_CP007389.1\|WP_012057040.1\|858391_859639_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|224567

Protein	Function_ID	Function_description	E-value
NZ_CP007389.1\|WP_012057041.1\|859675_860596_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.88616e-70
NZ_CP007389.1\|WP_012057042.1\|860592_861402_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	7.15982e-73
NZ_CP007389.1\|WP_012057051.1\|869709_869973_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	4.46807e-20
NZ_CP007389.1\|WP_012057038.1\|856820_857894_-\|MFS-transporter	gnl\|CDD\|340891	cd17333, MFS_FucP_MFSD4_like, Bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4, and similar proteins. This family is composed of bacterial L-fucose permease (FucP), eukaryotic Major facilitator superfamily domain-containing protein 4 (MFSD4) proteins, and similar proteins. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. The MFSD4 subfamily consists of two vertebrate members: MFSD4A and MFSD4B. The function of MFSD4A is unknown. MFSD4B is more commonly know as Sodium-dependent glucose transporter 1 (NaGLT1), a primary fructose transporter in rat renal brush-border membranes that also facilitates sodium-independent urea uptake. The FucP/MFSD4 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.05049e-15
NZ_CP007389.1\|WP_012057046.1\|864112_865987_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NZ_CP007389.1\|WP_012057039.1\|857896_858202_-\|rubrerythrin	gnl\|CDD\|275328	TIGR04535, conserved_hypothetical_protein, ferritin-like protein. Two families of proteins are known to be encoded, with some regularity, next to the gene for encapsulin (pfam04454), with surrounds the target protein to form a prokaryotic proteinaceous organelle. One is the family of enzymes that includes Dyp-type peroxidases. The other is this family, with a resemblance to bacterioferritins. Encapsulin-associated forms of the proteins in these two families have a necessary C-terminal motif that resembles DGSL[SGN]IGSL[KR]. Members of this family that include the last columns of the model in the hit region (and are encoded next to the encapsulin gene) should be designated encapsulin-associated ferritin-like protein.	3.95173e-23
NZ_CP007389.1\|WP_012057045.1\|862998_864093_-\|DUF445-family-protein	gnl\|CDD\|377281	pfam04286, DUF445, Protein of unknown function (DUF445). Predicted to be a membrane protein.	1.25229e-14
NZ_CP007389.1\|WP_012057056.1\|874640_875453_+\|Mrp/NBP35-family-ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	1.97217e-136
NZ_CP007389.1\|WP_143611012.1\|854323_854929_-\|glycerol-3-phosphate-acyltransferase	gnl\|CDD\|172882	PRK14406, PRK14406, glycerol-3-phosphate acyltransferase.	1.62933e-106
NZ_CP007389.1\|WP_012057052.1\|870081_871419_+\|MATE-family-efflux-transporter	gnl\|CDD\|240539	cd13134, MATE_like_8, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.34351e-108
NZ_CP007389.1\|WP_012057037.1\|855753_856818_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|376768	pfam02350, Epimerase_2, UDP-N-acetylglucosamine 2-epimerase. This family consists of UDP-N-acetylglucosamine 2-epimerases EC:5.1.3.14 this enzyme catalyzes the production of UDP-ManNAc from UDP-GlcNAc. Note that some of the enzymes is this family are bifunctional, in these instances Pfam matches only the N-terminal half of the protein suggesting that the additional C-terminal part (when compared to mono-functional members of this family) is responsible for the UPD-N-acetylmannosamine kinase activity of these enzymes. This hypothesis is further supported by the assumption that the C-terminal part of rat Gne is the kinase domain.	6.89924e-132
NZ_CP007389.1\|WP_012057053.1\|871415_873149_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	1.52295e-146
NZ_CP007389.1\|WP_012057050.1\|868547_869633_-\|permease	gnl\|CDD\|281730	pfam03773, ArsP_1, Predicted permease. This family of integral membrane proteins are predicted to be permeases of unknown specificity.	1.33911e-75
NZ_CP007389.1\|WP_012057048.1\|867583_868255_-\|DNA/RNA-nuclease-SfsA	gnl\|CDD\|224406	COG1489, SfsA, DNA-binding protein, stimulates sugar fermentation [General function prediction only].	4.6504e-71
NZ_CP007389.1\|WP_012057049.1\|868299_868536_-\|thioredoxin-family-protein	gnl\|CDD\|379063	pfam13192, Thioredoxin_3, Thioredoxin domain.	3.00213e-25
NZ_CP007389.1\|WP_012057040.1\|858391_859639_+\|extracellular-solute-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	8.49442e-39

>NZ_CP007389.1|WP_012057046.1|864112_865987_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MFFERPKDDIEFDVIVVGTGHAGIEAALAPARLGLRTLILTTNLDNVGWAPCNPAIGGPAKGIVVREIDVLGGEMAKTTDETMINVRMLNTGKGPAVRALRAQIDKYAYSQMMKNKLQSQENLVLRFGLVEKILVKDGKVYGVVDSFGIDYRAKAVILTTGTFLRGKIFIGRDTMEAGRMGDLPAKGLSKSLMDIGFKLSRFKTGTPSRVLKSSINFSKMIRQDTDDEPRAFSHFSEPKVLPKDHPCWLTHTNEKTHKIIRDYLVYSPLYGKVKLIQSVGPRYCPSIEDKVVKFNRDSHQVFVEPEGKNSQEYYLNGLSTSLPYAAQIKMLRTIPGLENVVIVRPAYAIEYDYIDPLQLYQTLESKLIEGLYFAGQINGTSGYEEAAGQGLVAGINAAMKILGEKPLILKRSESYIGILIDDLTTKGVDEPYRLLTSRAEYRLLLRHDNAHIRLAKYGYRVGLIPKWFYEKVLNLEKNIKLQIERLKNVKVPVSDRVNDILVKLGSTPLKEGTKLYNLLKRPEISYNDIEELDSERITDKELLEQIEIYIKYEGYIEKMLEEVKIFEEYESVDISKINLDKVPNLSTEAREKLKKVMPRSIGQAMRIPGVTPADIANIISYIEK
>NZ_CP007389.1|WP_012057045.1|862998_864093_-|DUF445-family-protein
MNILIKLSKDIIFWILVFLLLISHIFTLNIIKVTSIGALVGYITNVLAIWMLFNPKKKFFGFQGVIPKKRDEIALNTSKIIENEFINAKSIRQFIENNKEIFAEMLFDFVEKQGNKVIPPISKIFQNKTAEVAEKMAEKLKLDNKDSLWENLKNKSISAFCSPEMLINFILKILENEEFVNFTKHQVAKQVKIPLLPVDSIIANIVDKFLNNITYTLKLKGDEYHKLIEYLKEKCDTLKVKDIIEKDDFFHLVDFLNTKSKDFFKSIILNLFNQEINVKYILNILNVKEIITHLIDRYEKNIIDIAEKLLQKISFKDIVREKIESYSIEEMEKVTLELAKRELRYVEIFGIPLGILISIFQIIF
>NZ_CP007389.1|WP_012057042.1|860592_861402_+|carbohydrate-ABC-transporter-permease
MKKFFSYFFLIIIAIYIIIPLYVLLATTFKPLGEIGISDMWKLPRNWSLNGFIKAFNKLSPNLKNSFYLTIPATIVSALIGSINGYVFSKIRFKSANIIFAIILFGMFIPYQSILFPLIRFLQKINLYGTITGLIVVHIVYGIPITTLVFRNYYSEVPDELVEAAYMDGAGFFKTYSKVLFPISIPAFVVVIIWQFTNIWNEFLFAVTVTSNPAKQPITVALVNLAGSQVVEWNVQMAGAIITALPTLVVYILLGKYFIRGLLAGSVKG
>NZ_CP007389.1|WP_012057041.1|859675_860596_+|sugar-ABC-transporter-permease
MRKKNLIIGISIILPSIIAIAVFVYGFISWTVRTSFSNWNSFSALLRGTYKFVGLRNYIRLFQDSRFQIDLWNTLFFTVFFLLGTITLGVVMAILVDKGLKGSRIFQNLFLFPMAISFVVTGTVWSWIFAPGNIPSNPQGINLLFQKLGLEKLMWGWYTSTYSIGKFNVALIPVIIAAIWQLSGYTMAMYLAGLRGIPNDIIEAAKVDGASEWKIFWKIKMPLLTPITLSALIILGHISLKIFDLVFSMTGSGPNFVTDVPAIYMFELTFRSNRYAMGSAIAIVMLLFVTVVIIPYLITSLRGERR
>NZ_CP007389.1|WP_012057040.1|858391_859639_+|extracellular-solute-binding-protein
MKKFIIFFLAILLTLSVFAQENALEIFSWWTGGGEEEGLLALFKLFNEHYPDVKIINAAVAGGAGTNAKAVLKTRMLGGNPPDSFQVHAGMELTDTYVIPGLMEPITWILKEIDAYDKFPKDLIDIVSYEGEVYSIPVNVHRANVVFYNKEIAKKIGMTKEPTTWTEFLTYLDKAQKMGYAGISLGDKNKWTSLHLFESIMLSQLGPEKYNKLWKGEASFNDPAIKQALIILKDVLNYVNSDHSALTWQDATRMVFEGKAFCNMMGDWAEGYLKTLGWKPGVEFGWFALPGTQNAFMLVSDTFGLPKNAPHRENAIKWLKFLATVEAQDTFNPIKGSIPARIDADKSKYDSYLKWSMNDFSTKVISPSIIHGSAAPESFATALMDAINIFVTEKNVDKTFKEILWIAEDNGYVTD
>NZ_CP007389.1|WP_012057039.1|857896_858202_-|rubrerythrin
MPEFSNPFSGLKHKRKLSDEELVRAIRYMIAAEYEAIQLYMQLAESTDNKLAKEVLIDIANEERVHAGEFLRLLKELDPEEEKFYEEGAKEVEEEIKKLGG
>NZ_CP007389.1|WP_012057038.1|856820_857894_-|MFS-transporter
MYYVVLNIFFGSLIVNSIAPLMPIFQEEFSLSVSLSSFIPILNTLGNIFFSFAASLIINKSGLRLLNLLSYTFILLALFFLTFFKSLEIVLLSFFLIGAGVTIIFTTSTTILAHFKNPKFGILHAFFGLGGILSPFFVSIFLKNNISYRLLYFIYLLLILILLVWSFFKDFPKISKNIKISTTILKPIFIISIISFLLYSGSEISTVTWASNLFLNFGYSKESASLFLGIFWFLFTLSRFMMEIFLKFFTENTLITFFSISSAILLILTVFLKTPVLFFVFGFFMGSIFPLMQRKANIRLSKDEVGFLNGVTYSATGIGALLFIALMGYVSKYSIPFMFLLPAIGLILVFALQKKEV
>NZ_CP007389.1|WP_012057037.1|855753_856818_-|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MNLAIVFGTRPEVIKVATVYLKAKEKGINVKMIATAQHREMMDMMLNVFDITPDYDMNIMKTNQSLNHVCASVFTKLDDIIVKEQSDWILVQGDTSTAMAGAICAFNREVKVGHIEAGLRSNNLKDPFPEEMNRRVIDQVSDLMFAPTKRAAENLEKEGHSKERIKVTGNTVVDALMYIKEKFDLENIRKKIVREKDYILVTLHRRENWGEKMINILKGIKRFSKETGKKIVFPVHMNPKVRKVVFEELENFKNAILIEPLNYVEFLSILSDASIVASDSGGIQEEAPSFGKFVVVCRNTTERPELIKEGFGILAGTSEEGVYKALIEGSSKKLENKNPFGDGLASERIVSLIE
>NZ_CP007389.1|WP_012057036.1|854925_855726_-|hypothetical-protein
MEKTILISALLAVLVIGSFLFLFSGKKILEFDDIVLRELPSNAIIVEKDISVSKRIKQLYNEGQLFVFEGIYVTNQKHENEAFQQAANKARQELSTFLGAKISSDANLKEKMSGIREAFGYSQDVNIVVNNFVSSSKIIAKWKVPQGKGVFEYHVLVYYDPDLFNTFVKEQKKKQELYHIVIDLETRSVIKNVKIDNFESIRQEFERAKKIGDVITLEVVNGKINAKEKAPILYLLRNARLKDGRYRGLYYKTSNKLILFVFREAK
>NZ_CP007389.1|WP_143611012.1|854323_854929_-|glycerol-3-phosphate-acyltransferase
MVEYIYSIFIGYFFGAIPFSFFIAKLKGIDIRKTGSGNVGGTNVLRNAGAFYGALAFFFDIFKAYIAVFLVKGFGIKFMLIAGTMAVLGHCYSIFLKFKGGKGVASTFGVFLAVYPWSGLVFFGVWLFIVAVTKYVSLASMIGLIFASIFVFFAGKDFWVIFLALSLFSILRHKDNIQRLINGNERKTDVIGYFFGKGKKN
>NZ_CP007389.1|WP_012057048.1|867583_868255_-|DNA/RNA-nuclease-SfsA
MMNIIKIDNTQSGIFLERINKYLAKIYLNENVVDVHVHDPGRLKELLFKNNKVLVKKVNSTNRKTKYDLIAAKKEKEYVLVHSMYHRYIAEKILRKKYTHLKAEVKYKNSRIDFLAEDKFWIEIKGCTLSDGNMARFPDAPTKRGTKHLEDLMELKKQGFDTFIYFLIFANANYFSPNYETDLSFSKKLEEAYSLGVKIVPLLFSLENNWIVFKREIQLIFDG
>NZ_CP007389.1|WP_012057049.1|868299_868536_-|thioredoxin-family-protein
MKKIEILGSGCPKCKQTEKIMKIAVKDLEIDAKIEKVTDIDEIISRGVVATPAVAIDGKVVISGKIPTLEEAKELLNN
>NZ_CP007389.1|WP_012057050.1|868547_869633_-|permease
MKEFVLVLVIFLIFYFVPFNTNIVQNSILNGFLMLQEYAREHVLLCLVPAFFIAGTISVMLNKSAVLKLLGPKAKKIISYPVAAISGGILAVCSCTILPLFGGIYKKGAGIGPATTFLFSGPAINIAAIFLTARVLGWNLGLARLFATITAAILIGLIMESLFQEKGEGGFHIQEESKNGTKVLIFFSLQLSFLIISGLKINYLVKYSLMSLTSLSVVIMAVFFFKKEETKSWLEETWDFAKKILPYLFIGVFFSGILTKLLPQEIVTKFLGNNGILSNLFASIIGMFMYFATLTEVPIVQALRELGMAKGPTLALLMAGNSLSLPSMIVITKLFGRKKAFSYFSLVVLFSTIFGIIYGHI
>NZ_CP007389.1|WP_012057051.1|869709_869973_-|winged-helix-turn-helix-transcriptional-regulator
MEEKIISTANILKAMGHPTRLKILYLLNKKPHCVCELLDILKVSQPNLSQHLALLRNMGIIKDERKANMVFYSLENEFVKKVLSLLD
>NZ_CP007389.1|WP_012057052.1|870081_871419_+|MATE-family-efflux-transporter
MGIYRDLFKIAIPVALQQFLFSSVSFLDTLMIGRLGEDAIAAIGLANQFFFFYNIVLFGLVSGGAIFFSQFWGKGDFEGLSKSTALTTLSSLFVSIPFFVLSLFFPGYVMRFFSPDPIVIELGVKYIKILSISFPIFAISMVFSFMLRSIHKAHIPMYTTIIELTTNVFLNYVLIFGNFGFPKLGVIGAAIATVFSRIIGLFVLIVTVKLQKLPGMFSLHHIGALNKNFINRFFHYTLPTLANEFAWSLGFTMYSVIYAHMSTKVIAARNIIGTIEGFAWAFSFSLANAASVIIGNYLGAKRFGEAYKISRKIIKLTEIVATISAAATYILTVFSVDLFNISQDVKSLVIVAMAISMGFVPIKIFNGLNIVGFLRAGGDTRFSFAVEATTLWVLGVPLAAIGGLILKLSFPLVLLLTMVDEITKFFILLSRYKSRKWVRNVVENI
>NZ_CP007389.1|WP_012057053.1|871415_873149_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MIVLNNVSLHFPGKELLNNVSLNISDGEKVALIGKNGSGKTTLLKAIVGEFKEYTGQINTTGKVVYLDQYRTFSSNTPYEYYMEVADTPEKERLVRSILKGFGFEEEDWKRNLSTFSGGEKTRLQIGRLFLEEADFILLDEPTNYLDIAGIHFLKNLLKSFKGGYIIISHDRSFLRDTCERFLEINNGKIWDFRMGFDAYLKERESLILHQKRSMKNKQREIERLKKIIERYRKWGREKFIKQAKSKEKILQKILEELQSEVIFEEETKKNVSIPIPENTGYIVLNVKGLKFLNIIDDVTFTVYSGDKIAILGPNGSGKSTILKFISGKLKGEGLVEFGYNVKVEFLDQFVEELDEENSVFEEIANEMEMQPDYVIRAYAGRFGFKGEDVFKTISELSGGERQILALAKVLLKKPNLLILDEPTNHMDLETVEALEDALKEYKGSLILVSHDEELVKNVCNRYFILKDKKLLEVSDISQYEPKEEKKEEKIINTDYEEKKRRKNRIKKLKMEIEKLNEEEKRLLKKIDEIDLKLLNVGSDYIKAMELSEEKEKLEEKILNLLQKIDEMEKEIKYLEI
>NZ_CP007389.1|WP_012057054.1|873154_873559_-|hypothetical-protein
MKKFFGYMFFGISVLPILLPIFFSFVALFTKKGFLYDYLMPAELIGFTIIGSIGIIFFALKKHVMVKKLIYFLTLEIASILFAQIYSVAAGLAHGDTQPVGIHAWIIGICIVLWHLFLILLCIENFKVLKKSLR
>NZ_CP007389.1|WP_041425982.1|873619_874051_-|hypothetical-protein
MRKEIYLFLIFLILFFSLTYLEFKEVNVGGIVFVSTLFLLYLNFRLNKNLFFRNFLLFFVIIIFIPIVIFFKFKTIYIFFPLLFIGNVSITEKKQKNILLILSFIILLEMLLLGIPYSFSISYFFVCLLPLFLSKKKNEMQSN
>NZ_CP007389.1|WP_012057055.1|874062_874356_-|hypothetical-protein
MKNTGYILYGNEDFKLDPGNGGYSIASIYVNVFVTEWIDHEFGNVKSKIYNFLDKVIVTSITKAYEYARNFMIKQINRLKRLYPNSEINGSYNIDIK
>NZ_CP007389.1|WP_012057056.1|874640_875453_+|Mrp/NBP35-family-ATP-binding-protein
MPNPQFNLNNDNEKIKEKMSKVKHKIAVLSGKGGVGKTTVAVNLATALAESGYRVGILDLDMHGPNIVRMLGEKNPTVDGEEIVPAEILPNLKALSIGMLVESGKAVIWRGPLKHSAIKQFLGDTKWGELDYLIFDLPPGTGDEALSLFQTIPELDGVVMVTTPQKVALDDVRRAIDFVHAMNKKLLGIVENMSYVKCPKCEEKIEIFGSGGGKILAEEYNVELLGQIPLDPKAAKYADEGKPITLYMRESEVEAEFRKIVEKIAKIVEK

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Crispr_ID: NZ_CP007389_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007389_5

1638809-1639894

TypeIII

Consensus_repeat	Method
GTTTCCATTCCTCATAGGTAGATTCTAAAC	PILER-CR
GTTTAGAATCTACCTATGAGGAATGGAAAC	CRISPRCasFinder
GTTTAGAATCTACCTATGAGGAATGGAAAC	CRT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	PILER-CR

15 spacers

cas2,cas1,csm6,cmr1gr7,cas10,cmr3gr5,cmr4gr7

The CRISPR arrays of NZ_CP007389_5

>merge|NZ_CP007389|5|1638809-1639894|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTTAGAATCTACCTATGAGGAATGGAAACCTACAGTTACCGCCACACCCCCTTCTTTCAAAAATTTGTTTAGTTTAGAATCTACCTATGAGGAATGGAAACTTAAATAATTTACTTAAATCAGCACGACGAATAACTTCATGTTTAGAATCTACCTATGAGGAATGGAAACTAAATTTATAACTCCAATTCCGTATTTTTCCTTTACCTCCGTTTAGAATCTACCTATGAGGAATGGAAACTCCCTGGGGGCGATCACCCCCAAGGATGAGAAAAGAGTTTAGAATCTACCTATGAGGAATGGAAACTTCCAGGGAGCCTCCCATATATCGGGGTCCCTGTTTGTTTCGTTTAGAATCTACCTATGAGGAATGGAAACATCATAACAAGGCCATCATAACCAGCTGCACCAATTTTCGTTTAGAATCTACCTATGAGGAATGGAAACAAAAAAGAAGAGGAGCAAAACTAACGCTCCTCTTCTTCGTTTAGAATCTACCTATGAGGAATGGAAACCACCTCCCCCCAAAATTTTTGTTTCAACCTCCATGCTTTCCCCGTTTAGAATCTACCTATGAGGAATGGAAACCAAGGTTTTCCACAAGGGTGGTACGCGGCAACTCAAAAGTTACCGTTTAGAATCTACCTATGAGGAATGGAAACTACTGGGCAACGTTAATGAATGTCCTGACGGAAGAATAAAATAGTTTAGAATCTACCTATGAGGAATGGAAACTTGTAAAAATATGCAACTATATCCTCTACCCTATATGTATTTTGTTTAGAATCTACCTATGAGGAATGGAAACCATTAGAATTGAGAACTCCTATATATTCAATATCATGCAAGTGTTTAGAATCTACCTATGAGGAATGGAAACGAAAAATCACCAGTTCTATCATTTCTTGTTTATTCATAGTTTAGAATCTACCTATGAGGAATGGAAACCGATTGTGATTTCAGATATGATTCGCCATTGTCAAGTGTTTAGAATCTACCTATGAGGAATGGAAACTCTCTTGTTTTGTTAATTCTTCTTCGCATTCTTTGATGCGGTTTAGAATCTACCTATGAGGAATGGAAAC

>NZ_CP007389|5|4|1638809-1639324|PILER-CR
GTTTAGAATCTACCTATGAGGAATGGAAAC	CTACAGTTACCGCCACACCCCCTTCTTTCAAAAATTTGTTTA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTAAATAATTTACTTAAATCAGCACGACGAATAACTTCAT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TAAATTTATAACTCCAATTCCGTATTTTTCCTTTACCTCC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCCCTGGGGGCGATCACCCCCAAGGATGAGAAAAGA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTCCAGGGAGCCTCCCATATATCGGGGTCCCTGTTTGTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	ATCATAACAAGGCCATCATAACCAGCTGCACCAATTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	AAAAAAGAAGAGGAGCAAAACTAACGCTCCTCTTCTTC
GTTTAGAATCTACCTATGAGGAATGGAAACCACCTCCCCCCAAAATTTTTGTTTCAACCTCCATGCTTTCCCCGTTTAGAATCTACCTATGAGGAATGGAAAC	CAAGGTTTTCCACAAGGGTGGTACGCGGCAACTCAAAAGTTACC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TACTGGGCAACGTTAATGAATGTCCTGACGGAAGAATAAAATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTGTAAAAATATGCAACTATATCCTCTACCCTATATGTATTTT
GTTTAGAATCTACCTATGAGGAATGGAAAC	CATTAGAATTGAGAACTCCTATATATTCAATATCATGCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	GAAAAATCACCAGTTCTATCATTTCTTGTTTATTCATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	CGATTGTGATTTCAGATATGATTCGCCATTGTCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCTCTTGTTTTGTTAATTCTTCTTCGCATTCTTTGATGCG


>NZ_CP007389|5|5|1638809-1639894|CRISPRCasFinder
GTTTAGAATCTACCTATGAGGAATGGAAAC	CTACAGTTACCGCCACACCCCCTTCTTTCAAAAATTTGTTTA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTAAATAATTTACTTAAATCAGCACGACGAATAACTTCAT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TAAATTTATAACTCCAATTCCGTATTTTTCCTTTACCTCC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCCCTGGGGGCGATCACCCCCAAGGATGAGAAAAGA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTCCAGGGAGCCTCCCATATATCGGGGTCCCTGTTTGTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	ATCATAACAAGGCCATCATAACCAGCTGCACCAATTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	AAAAAAGAAGAGGAGCAAAACTAACGCTCCTCTTCTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	CACCTCCCCCCAAAATTTTTGTTTCAACCTCCATGCTTTCCCC
GTTTAGAATCTACCTATGAGGAATGGAAAC	CAAGGTTTTCCACAAGGGTGGTACGCGGCAACTCAAAAGTTACC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TACTGGGCAACGTTAATGAATGTCCTGACGGAAGAATAAAATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTGTAAAAATATGCAACTATATCCTCTACCCTATATGTATTTT
GTTTAGAATCTACCTATGAGGAATGGAAAC	CATTAGAATTGAGAACTCCTATATATTCAATATCATGCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	GAAAAATCACCAGTTCTATCATTTCTTGTTTATTCATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	CGATTGTGATTTCAGATATGATTCGCCATTGTCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCTCTTGTTTTGTTAATTCTTCTTCGCATTCTTTGATGCG
GTTTAGAATCTACCTATGAGGAATGGAAAC

>NZ_CP007389|5|4|1638809-1639894|CRT
GTTTAGAATCTACCTATGAGGAATGGAAAC	CTACAGTTACCGCCACACCCCCTTCTTTCAAAAATTTGTTTA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTAAATAATTTACTTAAATCAGCACGACGAATAACTTCAT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TAAATTTATAACTCCAATTCCGTATTTTTCCTTTACCTCC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCCCTGGGGGCGATCACCCCCAAGGATGAGAAAAGA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTCCAGGGAGCCTCCCATATATCGGGGTCCCTGTTTGTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	ATCATAACAAGGCCATCATAACCAGCTGCACCAATTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	AAAAAAGAAGAGGAGCAAAACTAACGCTCCTCTTCTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	CACCTCCCCCCAAAATTTTTGTTTCAACCTCCATGCTTTCCCC
GTTTAGAATCTACCTATGAGGAATGGAAAC	CAAGGTTTTCCACAAGGGTGGTACGCGGCAACTCAAAAGTTACC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TACTGGGCAACGTTAATGAATGTCCTGACGGAAGAATAAAATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTGTAAAAATATGCAACTATATCCTCTACCCTATATGTATTTT
GTTTAGAATCTACCTATGAGGAATGGAAAC	CATTAGAATTGAGAACTCCTATATATTCAATATCATGCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	GAAAAATCACCAGTTCTATCATTTCTTGTTTATTCATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	CGATTGTGATTTCAGATATGATTCGCCATTGTCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCTCTTGTTTTGTTAATTCTTCTTCGCATTCTTTGATGCG
GTTTAGAATCTACCTATGAGGAATGGAAAC

>NZ_CP007389|5|5|1639368-1639894|PILER-CR
	CTACAGTTACCGCCACACCCCCTTCTTTCAAAAATTTGTTTA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTAAATAATTTACTTAAATCAGCACGACGAATAACTTCAT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TAAATTTATAACTCCAATTCCGTATTTTTCCTTTACCTCC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCCCTGGGGGCGATCACCCCCAAGGATGAGAAAAGA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTCCAGGGAGCCTCCCATATATCGGGGTCCCTGTTTGTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	ATCATAACAAGGCCATCATAACCAGCTGCACCAATTTTC
GTTTAGAATCTACCTATGAGGAATGGAAAC	AAAAAAGAAGAGGAGCAAAACTAACGCTCCTCTTCTTC
GTTTAGAATCTACCTATGAGGAATGGAAACCACCTCCCCCCAAAATTTTTGTTTCAACCTCCATGCTTTCCCCGTTTAGAATCTACCTATGAGGAATGGAAAC	CAAGGTTTTCCACAAGGGTGGTACGCGGCAACTCAAAAGTTACC
GTTTAGAATCTACCTATGAGGAATGGAAAC	TACTGGGCAACGTTAATGAATGTCCTGACGGAAGAATAAAATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	TTGTAAAAATATGCAACTATATCCTCTACCCTATATGTATTTT
GTTTAGAATCTACCTATGAGGAATGGAAAC	CATTAGAATTGAGAACTCCTATATATTCAATATCATGCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	GAAAAATCACCAGTTCTATCATTTCTTGTTTATTCATA
GTTTAGAATCTACCTATGAGGAATGGAAAC	CGATTGTGATTTCAGATATGATTCGCCATTGTCAAGT
GTTTAGAATCTACCTATGAGGAATGGAAAC	TCTCTTGTTTTGTTAATTCTTCTTCGCATTCTTTGATGCG
GTTTAGAATCTACCTATGAGGAATGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007389.1\|WP_143611087.1\|1632338_1633481_-\|DNA-recombination-protein-RmuC	unknown	unknown	gnl\|CDD\|224241
NZ_CP007389.1\|WP_012057853.1\|1640277_1640538_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP007389.1\|WP_012057846.1\|1631325_1632105_+\|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl\|CDD\|319354
NZ_CP007389.1\|WP_012057852.1\|1636860_1637817_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP007389.1\|WP_012057851.1\|1636126_1636861_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|227320
NZ_CP007389.1\|WP_041426266.1\|1641542_1641812_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP007389.1\|WP_012057844.1\|1629186_1630107_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223489
NZ_CP007389.1\|WP_012057861.1\|1644953_1647149_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NZ_CP007389.1\|WP_077277096.1\|1642634_1643777_+\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NZ_CP007389.1\|WP_012057850.1\|1635189_1636122_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225183
NZ_CP007389.1\|WP_012057845.1\|1630197_1631313_+\|lysoplasmalogenase	unknown	unknown	gnl\|CDD\|377946
NZ_CP007389.1\|WP_155760994.1\|1642202_1642349_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_041426111.1\|1638066_1638372_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057860.1\|1643812_1644937_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|224286
NZ_CP007389.1\|WP_012057854.1\|1640550_1641537_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP007389.1\|WP_143611040.1\|1647132_1648110_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NZ_CP007389.1\|WP_012057849.1\|1634007_1634874_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP007389.1\|WP_012057863.1\|1648122_1648953_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NZ_CP007389.1\|WP_012057848.1\|1633680_1633950_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP007389.1\|WP_012057858.1\|1642396_1642579_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP007389.1\|WP_143611087.1\|1632338_1633481_-\|DNA-recombination-protein-RmuC	gnl\|CDD\|224241	COG1322, COG1322, Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only].	6.88565e-16
NZ_CP007389.1\|WP_012057853.1\|1640277_1640538_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.78228e-26
NZ_CP007389.1\|WP_012057846.1\|1631325_1632105_+\|peptidoglycan-editing-factor-PgeF	gnl\|CDD\|319354	cd16833, YfiH, protein of unknown function YfiH. This subfamily contains YfiH, a protein of unknown function from Shigella flexneri, E. coli, and many similar proteins which collectively are often called DUF152. The structure of YfiH reveals a distant homology to Rho-activating toxins cytotoxic necrotizing factor 1 (CNF1) as well as chemotaxis protein CheD that stimulates methylation of methyl-accepting chemotaxis proteins (MCPs), all having an invariant Cys-His pair forming a catalytic dyad, and is required by the CNF-1 toxins for deamidation activity.	2.83331e-64
NZ_CP007389.1\|WP_012057852.1\|1636860_1637817_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.98793e-12
NZ_CP007389.1\|WP_012057851.1\|1636126_1636861_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	1.11472e-74
NZ_CP007389.1\|WP_041426266.1\|1641542_1641812_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.47113e-26
NZ_CP007389.1\|WP_012057844.1\|1629186_1630107_-\|hypothetical-protein	gnl\|CDD\|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	6.10745e-09
NZ_CP007389.1\|WP_012057861.1\|1644953_1647149_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.08691e-101
NZ_CP007389.1\|WP_077277096.1\|1642634_1643777_+\|putative-CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	5.15921e-54
NZ_CP007389.1\|WP_012057850.1\|1635189_1636122_-\|hypothetical-protein	gnl\|CDD\|225183	COG2274, SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].	3.00969e-07
NZ_CP007389.1\|WP_012057845.1\|1630197_1631313_+\|lysoplasmalogenase	gnl\|CDD\|377946	pfam07947, YhhN, YhhN family. The members of this family are similar to the hypothetical protein yhhN expressed by E. coli. Many are annotated as possible transmembrane proteins, and in fact they all have a high proportion of hydrophobic residues. A human member of this family, formerly known as TMEM86B, is a lysoplasmalogenase that catalyzes the hydrolysis of the vinyl ether bond of lysoplasmalogen. Putative conserved active site residues have been proposed for the YhhN family.	5.79546e-28
NZ_CP007389.1\|WP_012057860.1\|1643812_1644937_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	7.37859e-25
NZ_CP007389.1\|WP_012057854.1\|1640550_1641537_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.62296e-123
NZ_CP007389.1\|WP_143611040.1\|1647132_1648110_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.19551e-93
NZ_CP007389.1\|WP_012057849.1\|1634007_1634874_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.08705e-07
NZ_CP007389.1\|WP_012057863.1\|1648122_1648953_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	6.92764e-66
NZ_CP007389.1\|WP_012057848.1\|1633680_1633950_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.21759e-14

>NZ_CP007389.1|WP_041426111.1|1638066_1638372_+|hypothetical-protein
MKKFVKRSIFFHKNIDEMNNLIDKDRFYRICFKKCRDINFTLLENLLGFMIIQCMKNFQKHKKHSMFLLQNTKKTGLYVNIFHDLVLSETYKKISKVPEKY
>NZ_CP007389.1|WP_012057852.1|1636860_1637817_-|ABC-transporter-ATP-binding-protein
MKNFYKYFFIYHRLLPKSFRTKKFFIDLTYTLATILSFVIPFLLGKLIDSFGNSGKTLQIFLIFVLIYLSNFVLQQIEGYFRIIFSISSAPKFLIERSIENILKKGDINIIPEKEMDKIFSFKHIFEFFYNRFSIFVFLLPFLMAFSILILLFFNWKIGIIATFGILITWISANKKVKIEEKVSKQMNESEYKTAETLSDVYSGYEELKSYETVPFTFNWIKDTYNYLVKSYDSFGKVELRFGVTYELLAILTTPLLIVFLSLEVYFGKITPGIALMLFSFAEKLSSFSQVYIHDTDYISWVISRAKVAYNDYLREGK
>NZ_CP007389.1|WP_012057851.1|1636126_1636861_-|ATP-binding-cassette-domain-containing-protein
MFRKLEFSNVTFQYKNKKILDNFNLTIKRDEKLAIVGSSGEGKTTLIRLLLRYISPHSGEIFVNKKSINEIEDWYKMIGVLSQRAHIFNRSIKDNLLVANPNAKEKDMYKALEMAGLKKFMETKTLDFVLGDEGKYISGGEKARIALARLLLRNPEIVILDEPLEGVDKLVEREVVENIKEFVKDKTLILISHRFSILSITDEFAVLENGKIVEKGKYDEHSENSLLKRFFKAEEELTKKFRKD
>NZ_CP007389.1|WP_012057850.1|1635189_1636122_-|hypothetical-protein
MKNFLKWIFKVPRKVIIMLVSMNIFGIISSFLISYSAILSRDIINYAISKDKDFAITGLLYVIAIISSHVLLVIGKSFVSFVKGRYLKYLGEYSFQKIMKKDFTNFSKKSPAFYSEITLRTTENMLNIISDYENTGGLVFAFKITFYMFTMYTLDKFSGFLMIIFAILILTFLAIANKFFYKNYKLVQDEFLNMKSYVSDMFSGIEEIILFESQEFEIKNFKNNFKKTWDKLTHTYKTDYFLTFFTRDIISTTFYLLIIYRGIQLSNVGTFFALTNLFALIKYHLLTSVGLWDNFREAIISAKQLSEIVE
>NZ_CP007389.1|WP_012057849.1|1634007_1634874_+|DMT-family-transporter
MHIFSAIVSAFSSSVTSIFGKLSFTIGATPLQILFIRFLFSFLFAFILFFLLRKKFSAKLFLFFGSLGILNYGIAAFLFFYGLTFLNPAYATVLFFTNPIFVLIIQWIFFKTQKSFFSALSIIFSFLGVILANIAESIFGSDNIIYGTFLVLGAAFLNALFISISGEKIKSLSTSVVENVFYTFLGTFVFYFLVILLFGQVHSLKLSYFPYGILLSVFSTFLPLSLNYFSLKKVESHSLAVIMPLEIVFASVLSYLIFKETFSLIKVIGFVFVGIAPVIDNLKNLRKS
>NZ_CP007389.1|WP_012057848.1|1633680_1633950_+|thioredoxin-family-protein
MKILYFKNDKCSVCEAMLPKIKKVADDYNIDFEVIDVIKNPEIAGQNLVLTVPTVLFVDNGTELTRFARNFSVSEIVSFIERYLEFVNN
>NZ_CP007389.1|WP_143611087.1|1632338_1633481_-|DNA-recombination-protein-RmuC
MSTYASIIISLSVGIFLGYKFGYRIGKNEKQAEEISTQISTINNLTIQIAELKAKYEEIEKTRLETERQREKLNEEKERRFNEFIENTHKLFSELSERTIKIDEQKDKRIEELVMQMKNFFEEQKKNTEKFLIEQGKSREEIEKRRDAQIEDMKRMISIFAKTVSGTKTRGITGEVLLKDALKESIKVGLIKTNLKTENGEVEFAWDLGDGKYIPIDSKLPDVFEILEKYNKTEDIIIREKLKKEIINKVKKEIKRVQKYQNLANTTDSCLLVLPEAIIDIAPELVGIGRENNVYICSYKDVFVIAHTLQDKYIRLKEEGDIGKYKQMVETLLQLLEKINKKAETIDRALTTIKNANEEIRNSTIKGKKISTSEETKKLQ
>NZ_CP007389.1|WP_012057846.1|1631325_1632105_+|peptidoglycan-editing-factor-PgeF
MQLGNYICKEINGFFLCKSSMLYQFKKLFHVVTTRKVRINGCSEELDFSLRNENSLKQFEYFLRFIGVEKKDVIFAEQVHGNRIECVKRRNLKDELNVIKGVDGLVTNEKGVFLITRFADCIPIIAYDSKRNVVGVAHSGWKGTLFEISKQLILKMNGEYGCFPEDIFVSLGPSIGPQSFEVKEDVLKMFYEKFGDGYIRRTNELTYINLWKIVEDQLSEVGVRNIEISMVDTVSFNDYFYSYRKEKKFKRFAVIVGLL
>NZ_CP007389.1|WP_012057845.1|1630197_1631313_+|lysoplasmalogenase
MKRLVVFFLFSVIMLFGVEFEFKIPIFDVENGIYEIYKFEKDNKVEYTVVFFDEDHPNFFIDFVYDVFRLFKWGRIYDVESFLVEGTNIIFKDDFCISSSYFQVENLHNYAELPLKDFESKNGKIIIYVSTWNHMFSNISLNDVKYASFSSTPLLGDRNYVEEKFRGNPRLIFSLLFAVLVIFFGILTMVRKSQNRDAVFFKVFTTLFCLLIAMVNSSGVEWLLVLGLFFGVVGDYFMEFDEKFLYGMFSFFVGHIFYSLGFLLKFGIPKFSIFILIYFFFLLFYFIILSKQVDLKVPMFLYGLAISTMFVFTFSSIDKMGYFLPLAGVLFIFSDFLIVVDKYIKKIPLSNVLILSTYFSSQLIISLSIIF
>NZ_CP007389.1|WP_012057844.1|1629186_1630107_-|hypothetical-protein
MYIYEYDKNIPFNLKEEKFNNYSILSFDVVYEPDVPEAKKIFVYKYLTKNPWGKIIVLHGIGNNHIPYLMWYAKQFSKLGLESYFLIFPYHLNRGKTNWEGGEPFYHHSPAHCIVRFHQAIKDVRRTIDLIEKNNDDIYIMGFSFGGMITTMTMALDKRIKAGIIAFSGGDWRWINWYSPYLEKVRNGYRKYSNEWGCVDEKKCVKLRSNAKKQLTKINNINDIFTLKPTCFHYDPISYAKFVTQPTLLFQGIFDKIIPAKATKSLFESLPNAKKILIPSGHKSSYMFRRIITKMSVNFLKKSKFS
>NZ_CP007389.1|WP_012057853.1|1640277_1640538_+|CRISPR-associated-endonuclease-Cas2
MYVIMVYDVNKKRVQKVLKTARKYLKWVQKSVFEGKITEKNLKKLRDQLLELINQEEDSIYWYIMEPEFKPYRKILGKSENISNLI
>NZ_CP007389.1|WP_012057854.1|1640550_1641537_+|type-I-B-CRISPR-associated-endonuclease-Cas1
METLYIFTDGELRRKNNALYLKPKDNNMKPLFVPLKSVSSLMIFSEVSMNKRFLDLLSKEGIPAFFYGYYENFIGTFYPKQVNKTGEMLVLQYKHYEDINKRLKIASEILNAAVDNMVNLLSSFKEITHTEIEYITKLKASFKKQRNIPALMAIEGNIRKVYYSAIGKIVGKKDFEFVERTKQPPKDKINALISFGNVVLYNIVLAEIYKTSLEPRISFLHEPNKRNFSLQLDISEIFKPIVVDKVVLKLINNGMIKKKDFENVKDGVYLSKEGKKKFVQELENRLEKKIFLYKDQRVTLKTVILHECYKLIRHLKGEEEYKGFVLKE
>NZ_CP007389.1|WP_041426266.1|1641542_1641812_+|CRISPR-associated-endonuclease-Cas2
MKYILVVYDVNEKRINKVHKVLKKYIIWQQNSTFEGNVTQANIKRMIYELNKKINSKEDSILIYFFNSKTVIRKEVDGIEKWNVSSNFI
>NZ_CP007389.1|WP_155760994.1|1642202_1642349_+|hypothetical-protein
MSYGWSDNTKTLVLGYVPVDFIANKNNYNLEVCTQSTHIKDLFFENSA
>NZ_CP007389.1|WP_012057858.1|1642396_1642579_+|hypothetical-protein
MYGKHVQDVEQNVRIMKSIVTSVAGLFTTNLNYDDHWDFWRELAEDTLGVDLDGISGARV
>NZ_CP007389.1|WP_077277096.1|1642634_1643777_+|putative-CRISPR-associated-protein
MGGVDVKTLINTVGASLINNLQKIGLKEAFENGEIDKITKSLLEIEGNPENLREFGAEINSIVSIIKKGYLTERKNLYFLVSDTDEGKKIGEILKGYFENIKNFNFEKVTVCVIEKLNDARPYDFKIHGLRNLIKKIAEFVRKHYGEVIINATGGYKAQIAFALALGQTLKVPVYYRFERFPEVIELEPLPLDLDKNYYFLARNLFEQIDNSLGKFVEFGEVEIQYKILPVEAKIFFDIEKIDGKKYLSISPMGQIYLESIRSKFYFLNKEIQLEKRKGEIKFISSGKEGHSIQIINNYSLKDLFERFKYITSLRVTRASQSERTSSSKVKIVGNKLIIILHTKKGLIHFEAETTARNEEELEIIRLRLEEFLDENFDGR
>NZ_CP007389.1|WP_012057860.1|1643812_1644937_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MEKLKLTINFTTPSFASNNRKDFKLTSQTIRGILRFWFRAIIPRIINIHKYNECDKKFIGLKKAEELIFGSTERKSSFDLVIETVDKLLEKNNKNTYYLYGLEGRKFSRENSEFKLIFYIKNKQMEDSLKDLLKNLLLLISTVGGIGAKSRKGLGSFEVLGEKKYELEELLKILDNINKEIFKRRGFEFEPTKFDNKNVSDYPVLMDGYYEFFTKELKTKSLEKVFEILFHNSRDRNRKGIYLKTKYDLRMEGNDSFKKAINALNLNKRTTNIIFYQSILGLPINYYIRGKGQFKLESKGKENRKASPLFISIHRDKNNDYFVNFLIMKSKLTSDLEPKLVFGARNKIRNKIEIKGSHEYGKLIRNLRDNLEKV
>NZ_CP007389.1|WP_012057861.1|1644953_1647149_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MVWKKKIEIYKSIRDVFDSILKGNINGEPSILAKVNVNFLQEPEVIHPLTGERLKLEKQALKNLLENINFSKMKNFEFSNDFRKTFYELWWNIPKYLAIPFIIPENPKIPFSSIIDYLDNLSAQSITDNLSLLLVSIGPVQEFIAAARSTIDLKMGSYLLSYLVFQGIKVIGEGYGYDNIIFPYMRGSYFVKKEFEKFGIKVSNYLAPSVASLPNVFTAIVPTDELQELKKKIEIAVKTEMQQISDFVKSYVLKNRIIGNQQINLLDRFSKSWDKQIAQFPTIIMVEQEMGNLKEIVEQHFEYTKDENIKKLFESIETLGIPEQVFYGVFSELLGIKSALRKATRDFIQVYENSIQHGDDLSGENKSLVEILTKYGNEEKKEKLSAISTIKRFFVNYLEKIGYKEAYEKLKTIKSTEEIAGKYKIAALIMDGDNMGKWISGKLAPSMKNRVHTKVIEYFEKNQSNEIKNLKNLRLISPSYQRTISRTLNNFANFVPKIVEEFDGLLIYAGGDDVLALFPSNKVFEAANKIRKVYSGIGNIKIDNFIFKDGWCYINDEKIPLFNMMGKKLTMSVGISIANSKFNLKMLLNLARNMEKLAKSNVKNGREKSSFAVATIRRSGQIKESKIFWEVNDYDVINEAQNFIKKYESKKSMKRVVIRIMHEFENFGVPDNIISLEEFKGKVIPFIAEKIFFNDLCDEKFLDIKDKEEFEEYLRVLENLEYARKENENED
>NZ_CP007389.1|WP_143611040.1|1647132_1648110_+|type-III-B-CRISPR-module-associated-protein-Cmr3
MKMKIKVLYIKPIDVIGFRKSKTFSTTEASIFPNPKTFYGAIFAAYLRKNKLSVDDIEKIIENKKLSIIGPFLSNAYGEIFFKIPTIVKQNEKTGKFLKAFVDWNFSFYVNNKKLQGIRYENMRDLKEPKRRYISLKELEKLKIGRLDLDNEICEIYKHESKIGVALKNRKSIDGMLYSLTYYRFEENAGFAFFVENDELNILNELDLIKIGLKGKLARLEIGEVETSVFDKINDNKKGILLLTPSYFENGLLPKQDGNIIAIANYKPESIGFWDLKNNRPGEMFKVVPAGSVYFIDGDLPNSYKENFTDKFQEFNFGRYIEIKL
>NZ_CP007389.1|WP_012057863.1|1648122_1648953_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MNGKVGFLYAVTQIHAGKGMDLGVIDQPIQREIHTGFPIISGIKGALRHEINFENKEEIFGSEANKDKENSKPGDIVFSEVKILFFPVRSLNKGLVWITCPMVLSRLKTAFKIVGNNDLSKKIEDFLKNINHNEKYTTFEKEEVVSLEEYSIKPKRSDKLIEIVESLKEIVPDDYLSNMLTKNVVVLSEKDFTFFVRNATEILPRVRIDKSTRVVAKGALWYEEYLPQDTVMFFIIKSFTDNSELLNFVSKKIDGNYINIGGKTSVGKGFTYIKLL

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Crispr_ID: NZ_CP007389_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007389_6

1651085-1651956

TypeIII

Consensus_repeat	Method
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CRISPRCasFinder
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CRT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	PILER-CR

12 spacers

cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,cmr1gr7,csm6,csx1,csm2gr11,csm3gr7,csm4gr5

The CRISPR arrays of NZ_CP007389_6

>merge|NZ_CP007389|6|1651085-1651956|CRISPRCasFinder,CRT,PILER-CR
AATTCCATTTCTTATGGGGAGATACTAAACAAGAGATTGAGAGAAAAAATTATAAGAAGGCTCCCATGGATAGTTTCCATCTCTCATTAGCATATTCAAAACGGTTTTATATAGAAAATAGAAAAATACGCTGAGAGAATAGCGTGTTTCCATTCCTCATAGGTAGATTCTAAACAAAATAATAGAAACAAAAATCGTGGGTGGGGGGTTGCGGGTTTCCATTCCTCATAGGTAGATTCTAAACCCACGTCAGGGATGGTAGCAAGGGTGTCCACACACAGGTTTCCATTCCTCATAGGTAGATTCTAAACTAAATATTTATCAGAAAAAGGATTTTTAAAGGAAAATAGGTTTCCATTCCTCATAGGTAGATTCTAAACACTTATGTTTTTTAGATGAATTATTAAAGGAGATGAAAGAATGTTTCCATTCCTCATAGGTAGATTCTAAACCGCATCAAAGAATGCGAAGAAGAATTAACAAAACAAGAGAGTTTCCATTCCTCATAGGTAGATTCTAAACCAAATTAATTAACCAGGCACAAAAGGAAGTGGCTATTACCAGTTTCCATTCCTCATAGGTAGATTCTAAACTAGAGATTATTTTCGAAGAGGACTTTTAGTCCTCTTCTTTTGTTTCCATTCCTCATAGGTAGATTCTAAACGAAGAAGAGGAGCGTTAGTTTTGCTCCTCTTCTTTTTTGTTTCCATTCCTCATAGGTAGATTCTAAACGAAAATTGGTGCAGCTGGTTATGATGGCCTTGTTATGATGTTTCCATTCCTCATAGGTAGATTCTAAACGAAACAAACAGGGACCCCGATATATGGGAGGCTCCCTGGAAGTTTCCATTCCTCATAGGTAGATTCTAAAC

>NZ_CP007389|6|6|1651085-1651956|CRISPRCasFinder
AATTCCATTTCTTATGGGGAGATACTAAAC	AAGAGATTGAGAGAAAAAATTATAAGAAGGCTCCCATGGATA
GTTTCCATCTCTCATTAGCATATTCAAAAC	GGTTTTATATAGAAAATAGAAAAATACGCTGAGAGAATAGCGT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	AAAATAATAGAAACAAAAATCGTGGGTGGGGGGTTGCGG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CCACGTCAGGGATGGTAGCAAGGGTGTCCACACACAG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	TAAATATTTATCAGAAAAAGGATTTTTAAAGGAAAATAG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	ACTTATGTTTTTTAGATGAATTATTAAAGGAGATGAAAGAAT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CGCATCAAAGAATGCGAAGAAGAATTAACAAAACAAGAGA
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CAAATTAATTAACCAGGCACAAAAGGAAGTGGCTATTACCA
GTTTCCATTCCTCATAGGTAGATTCTAAAC	TAGAGATTATTTTCGAAGAGGACTTTTAGTCCTCTTCTTTT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAGAAGAGGAGCGTTAGTTTTGCTCCTCTTCTTTTTT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAAATTGGTGCAGCTGGTTATGATGGCCTTGTTATGAT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAACAAACAGGGACCCCGATATATGGGAGGCTCCCTGGAA
GTTTCCATTCCTCATAGGTAGATTCTAAAC

>NZ_CP007389|6|5|1651157-1651956|CRT
GTTTCCATCTCTCATTAGCATATTCAAAAC	GGTTTTATATAGAAAATAGAAAAATACGCTGAGAGAATAGCGT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	AAAATAATAGAAACAAAAATCGTGGGTGGGGGGTTGCGG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CCACGTCAGGGATGGTAGCAAGGGTGTCCACACACAG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	TAAATATTTATCAGAAAAAGGATTTTTAAAGGAAAATAG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	ACTTATGTTTTTTAGATGAATTATTAAAGGAGATGAAAGAAT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CGCATCAAAGAATGCGAAGAAGAATTAACAAAACAAGAGA
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CAAATTAATTAACCAGGCACAAAAGGAAGTGGCTATTACCA
GTTTCCATTCCTCATAGGTAGATTCTAAAC	TAGAGATTATTTTCGAAGAGGACTTTTAGTCCTCTTCTTTT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAGAAGAGGAGCGTTAGTTTTGCTCCTCTTCTTTTTT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAAATTGGTGCAGCTGGTTATGATGGCCTTGTTATGAT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAACAAACAGGGACCCCGATATATGGGAGGCTCCCTGGAA
GTTTCCATTCCTCATAGGTAGATTCTAAAC

>NZ_CP007389|6|6|1651230-1651956|PILER-CR
GTTTCCATTCCTCATAGGTAGATTCTAAAC	AAAATAATAGAAACAAAAATCGTGGGTGGGGGGTTGCGG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CCACGTCAGGGATGGTAGCAAGGGTGTCCACACACAG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	TAAATATTTATCAGAAAAAGGATTTTTAAAGGAAAATAG
GTTTCCATTCCTCATAGGTAGATTCTAAAC	ACTTATGTTTTTTAGATGAATTATTAAAGGAGATGAAAGAAT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CGCATCAAAGAATGCGAAGAAGAATTAACAAAACAAGAGA
GTTTCCATTCCTCATAGGTAGATTCTAAAC	CAAATTAATTAACCAGGCACAAAAGGAAGTGGCTATTACCA
GTTTCCATTCCTCATAGGTAGATTCTAAAC	TAGAGATTATTTTCGAAGAGGACTTTTAGTCCTCTTCTTTT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAGAAGAGGAGCGTTAGTTTTGCTCCTCTTCTTTTTT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAAATTGGTGCAGCTGGTTATGATGGCCTTGTTATGAT
GTTTCCATTCCTCATAGGTAGATTCTAAAC	GAAACAAACAGGGACCCCGATATATGGGAGGCTCCCTGGAA
GTTTCCATTCCTCATAGGTAGATTCTAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007389.1\|WP_012057872.1\|1657825_1660099_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP007389.1\|WP_012057867.1\|1653203_1653509_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_041426112.1\|1653508_1654183_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274357
NZ_CP007389.1\|WP_012057870.1\|1654971_1656405_+\|SAVED-domain-containing-protein	unknown	unknown	gnl\|CDD\|380122
NZ_CP007389.1\|WP_012057875.1\|1661371_1662313_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|187794
NZ_CP007389.1\|WP_012057874.1\|1660557_1661367_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP007389.1\|WP_155760994.1\|1642202_1642349_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_143611042.1\|1650541_1650691_-\|transposase	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057866.1\|1652549_1652687_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_077277096.1\|1642634_1643777_+\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NZ_CP007389.1\|WP_012057865.1\|1649351_1650167_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|213662
NZ_CP007389.1\|WP_077277097.1\|1656355_1657813_+\|TIGR01897-family-CRISPR-associated-protein	csx1	cd09728_csx1_CAS-III	gnl\|CDD\|187859
NZ_CP007389.1\|WP_012057869.1\|1654201_1654972_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057860.1\|1643812_1644937_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|224286
NZ_CP007389.1\|WP_143611040.1\|1647132_1648110_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NZ_CP007389.1\|WP_012057864.1\|1648962_1649334_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|187880
NZ_CP007389.1\|WP_012057863.1\|1648122_1648953_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NZ_CP007389.1\|WP_012057861.1\|1644953_1647149_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NZ_CP007389.1\|WP_012057858.1\|1642396_1642579_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007389.1\|WP_012057873.1\|1660100_1660541_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP007389.1\|WP_012057872.1\|1657825_1660099_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	4.1e-130	430.0	15.6
NZ_CP007389.1\|WP_012057875.1\|1661371_1662313_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	2.7e-63	208.7	8.3
NZ_CP007389.1\|WP_012057861.1\|1644953_1647149_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	1.4e-115	381.6	10.1
NZ_CP007389.1\|WP_077277096.1\|1642634_1643777_+\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	9e-51	166.5	0.2
NZ_CP007389.1\|WP_012057865.1\|1649351_1650167_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	1.1e-48	160.8	1.4
NZ_CP007389.1\|WP_077277097.1\|1656355_1657813_+\|TIGR01897-family-CRISPR-associated-protein	csx1	cd09728_csx1_CAS-III	2.4e-103	341.1	29.9
NZ_CP007389.1\|WP_012057860.1\|1643812_1644937_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	2e-38	127.1	12.5
NZ_CP007389.1\|WP_012057874.1\|1660557_1661367_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	1.6e-72	238.5	0.2
NZ_CP007389.1\|WP_012057864.1\|1648962_1649334_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	2.1e-28	93.9	0.7
NZ_CP007389.1\|WP_012057863.1\|1648122_1648953_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	1.6e-72	239.1	0.6
NZ_CP007389.1\|WP_143611040.1\|1647132_1648110_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	5.7e-71	234.4	0.0
NZ_CP007389.1\|WP_012057873.1\|1660100_1660541_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	2.1e-17	58.4	2.7

Protein	Function_ID	Function_description	E-value
NZ_CP007389.1\|WP_012057872.1\|1657825_1660099_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	3.67106e-122
NZ_CP007389.1\|WP_041426112.1\|1653508_1654183_+\|hypothetical-protein	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	6.05301e-05
NZ_CP007389.1\|WP_012057870.1\|1654971_1656405_+\|SAVED-domain-containing-protein	gnl\|CDD\|380122	pfam18145, SAVED, SMODS-associated and fused to various effectors sensor domain. Predicted to function as a sensor domain, sensing nucleotides or nucleotide derivatives generated by SMODS and other nucleotide synthetase domains. The sensing of ligands by SAVED is predicted to activate effectors deployed by a class of conflict systems which are reliant on the on the production and sensing of the nucleotide second messengers.	3.7558e-07
NZ_CP007389.1\|WP_012057875.1\|1661371_1662313_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|187794	cd09663, Csm4_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	8.62031e-50
NZ_CP007389.1\|WP_012057874.1\|1660557_1661367_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	2.9213e-79
NZ_CP007389.1\|WP_077277096.1\|1642634_1643777_+\|putative-CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	5.15921e-54
NZ_CP007389.1\|WP_012057865.1\|1649351_1650167_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.01911e-47
NZ_CP007389.1\|WP_077277097.1\|1656355_1657813_+\|TIGR01897-family-CRISPR-associated-protein	gnl\|CDD\|187859	cd09728, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as DxTHG family.	1.0972e-67
NZ_CP007389.1\|WP_012057860.1\|1643812_1644937_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	7.37859e-25
NZ_CP007389.1\|WP_143611040.1\|1647132_1648110_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.19551e-93
NZ_CP007389.1\|WP_012057864.1\|1648962_1649334_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	9.02163e-33
NZ_CP007389.1\|WP_012057863.1\|1648122_1648953_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	6.92764e-66
NZ_CP007389.1\|WP_012057861.1\|1644953_1647149_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.08691e-101
NZ_CP007389.1\|WP_012057873.1\|1660100_1660541_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	8.35997e-22

>NZ_CP007389.1|WP_143611042.1|1650541_1650691_-|transposase
MSKSTGANKHDSKIFEKTLEKNNRKPRAVAIDAGYKKVFILKSLFEKGI
>NZ_CP007389.1|WP_012057865.1|1649351_1650167_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MNYYKYDIEKLKDKNSFIKNASLYYNKFVFKELVVLNNKITSKSFKKSLKEIRERYKDVLISIIKNLFESSKSGSDSLQEIINSLRKIRENFINSLKQRYIILSYTLEVKTPFLIGAGIPSIDEIGFYWLRNYGIPVIPGTSIKGCFKSCLLDVLKDYLEEIFGTEDKMGKVIFLDAIPLGEICLGIDFQTPHFQKYYIDNKPPNDVYNPVPLSFLHVSKGRFRLDILIDKDEGNIADKIKNHIKIFLEEYGVGAKTSMGYGRFKIINQNS
>NZ_CP007389.1|WP_012057864.1|1648962_1649334_+|type-III-B-CRISPR-module-associated-protein-Cmr5
MERENKTKLIAKQLIVEKTSRNDLELKSYKSLIKGLGAMIIQNGLYGTLVFLKAKGENKTSKKHYHYVFEDIKHFLNEKGLFSNNDILEYLERTENLSEIQERVLELVNWYRRYVEIFISDED
>NZ_CP007389.1|WP_012057863.1|1648122_1648953_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MNGKVGFLYAVTQIHAGKGMDLGVIDQPIQREIHTGFPIISGIKGALRHEINFENKEEIFGSEANKDKENSKPGDIVFSEVKILFFPVRSLNKGLVWITCPMVLSRLKTAFKIVGNNDLSKKIEDFLKNINHNEKYTTFEKEEVVSLEEYSIKPKRSDKLIEIVESLKEIVPDDYLSNMLTKNVVVLSEKDFTFFVRNATEILPRVRIDKSTRVVAKGALWYEEYLPQDTVMFFIIKSFTDNSELLNFVSKKIDGNYINIGGKTSVGKGFTYIKLL
>NZ_CP007389.1|WP_143611040.1|1647132_1648110_+|type-III-B-CRISPR-module-associated-protein-Cmr3
MKMKIKVLYIKPIDVIGFRKSKTFSTTEASIFPNPKTFYGAIFAAYLRKNKLSVDDIEKIIENKKLSIIGPFLSNAYGEIFFKIPTIVKQNEKTGKFLKAFVDWNFSFYVNNKKLQGIRYENMRDLKEPKRRYISLKELEKLKIGRLDLDNEICEIYKHESKIGVALKNRKSIDGMLYSLTYYRFEENAGFAFFVENDELNILNELDLIKIGLKGKLARLEIGEVETSVFDKINDNKKGILLLTPSYFENGLLPKQDGNIIAIANYKPESIGFWDLKNNRPGEMFKVVPAGSVYFIDGDLPNSYKENFTDKFQEFNFGRYIEIKL
>NZ_CP007389.1|WP_012057861.1|1644953_1647149_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MVWKKKIEIYKSIRDVFDSILKGNINGEPSILAKVNVNFLQEPEVIHPLTGERLKLEKQALKNLLENINFSKMKNFEFSNDFRKTFYELWWNIPKYLAIPFIIPENPKIPFSSIIDYLDNLSAQSITDNLSLLLVSIGPVQEFIAAARSTIDLKMGSYLLSYLVFQGIKVIGEGYGYDNIIFPYMRGSYFVKKEFEKFGIKVSNYLAPSVASLPNVFTAIVPTDELQELKKKIEIAVKTEMQQISDFVKSYVLKNRIIGNQQINLLDRFSKSWDKQIAQFPTIIMVEQEMGNLKEIVEQHFEYTKDENIKKLFESIETLGIPEQVFYGVFSELLGIKSALRKATRDFIQVYENSIQHGDDLSGENKSLVEILTKYGNEEKKEKLSAISTIKRFFVNYLEKIGYKEAYEKLKTIKSTEEIAGKYKIAALIMDGDNMGKWISGKLAPSMKNRVHTKVIEYFEKNQSNEIKNLKNLRLISPSYQRTISRTLNNFANFVPKIVEEFDGLLIYAGGDDVLALFPSNKVFEAANKIRKVYSGIGNIKIDNFIFKDGWCYINDEKIPLFNMMGKKLTMSVGISIANSKFNLKMLLNLARNMEKLAKSNVKNGREKSSFAVATIRRSGQIKESKIFWEVNDYDVINEAQNFIKKYESKKSMKRVVIRIMHEFENFGVPDNIISLEEFKGKVIPFIAEKIFFNDLCDEKFLDIKDKEEFEEYLRVLENLEYARKENENED
>NZ_CP007389.1|WP_012057860.1|1643812_1644937_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MEKLKLTINFTTPSFASNNRKDFKLTSQTIRGILRFWFRAIIPRIINIHKYNECDKKFIGLKKAEELIFGSTERKSSFDLVIETVDKLLEKNNKNTYYLYGLEGRKFSRENSEFKLIFYIKNKQMEDSLKDLLKNLLLLISTVGGIGAKSRKGLGSFEVLGEKKYELEELLKILDNINKEIFKRRGFEFEPTKFDNKNVSDYPVLMDGYYEFFTKELKTKSLEKVFEILFHNSRDRNRKGIYLKTKYDLRMEGNDSFKKAINALNLNKRTTNIIFYQSILGLPINYYIRGKGQFKLESKGKENRKASPLFISIHRDKNNDYFVNFLIMKSKLTSDLEPKLVFGARNKIRNKIEIKGSHEYGKLIRNLRDNLEKV
>NZ_CP007389.1|WP_077277096.1|1642634_1643777_+|putative-CRISPR-associated-protein
MGGVDVKTLINTVGASLINNLQKIGLKEAFENGEIDKITKSLLEIEGNPENLREFGAEINSIVSIIKKGYLTERKNLYFLVSDTDEGKKIGEILKGYFENIKNFNFEKVTVCVIEKLNDARPYDFKIHGLRNLIKKIAEFVRKHYGEVIINATGGYKAQIAFALALGQTLKVPVYYRFERFPEVIELEPLPLDLDKNYYFLARNLFEQIDNSLGKFVEFGEVEIQYKILPVEAKIFFDIEKIDGKKYLSISPMGQIYLESIRSKFYFLNKEIQLEKRKGEIKFISSGKEGHSIQIINNYSLKDLFERFKYITSLRVTRASQSERTSSSKVKIVGNKLIIILHTKKGLIHFEAETTARNEEELEIIRLRLEEFLDENFDGR
>NZ_CP007389.1|WP_012057858.1|1642396_1642579_+|hypothetical-protein
MYGKHVQDVEQNVRIMKSIVTSVAGLFTTNLNYDDHWDFWRELAEDTLGVDLDGISGARV
>NZ_CP007389.1|WP_155760994.1|1642202_1642349_+|hypothetical-protein
MSYGWSDNTKTLVLGYVPVDFIANKNNYNLEVCTQSTHIKDLFFENSA
>NZ_CP007389.1|WP_012057866.1|1652549_1652687_+|hypothetical-protein
MKDKYFESAKITFRTSGNFFQEGQYQRMIQEFNKLSENKQLLLRY
>NZ_CP007389.1|WP_012057867.1|1653203_1653509_+|hypothetical-protein
MDSLWKARKRIRERRPLIVEEYGKNGYIIIFLSAKNYTKKHILVDKYCIIEENEVCNFLNKDSFLFEYKGEFLFYIPKQILERYFHLCGLCKISIDEFLKR
>NZ_CP007389.1|WP_041426112.1|1653508_1654183_+|hypothetical-protein
MFIVKKTLRELLKEYLEKNVVNRELFENVKGIVSSVMNTNPGYRDILIGIFGNSSSAINELTNEVFIRLKKKKNILINKTGDNLEGYLYMIVKNYIIDILRKTRVNDSLNDENGSNVEKIEYIRAEEHHFKPEWEIVAETFVEELKKLKAENLCYYLYKVMYSEEILFEEKSRDAKYKIVQRTKESLRELVVENGLNDKELTLAIRIYMSEICEKIRNISRKKN
>NZ_CP007389.1|WP_012057869.1|1654201_1654972_+|hypothetical-protein
MRFLENELNMYKKFLGEKFNIESLKKINGSKLNLGDIFVIYTPSFPIYGIVIDKSEDLNKCLYLTSELFLASAEAIRIKINHFANEVALTHIVFYISDDFAWNYCEVIGKFEDIKAIEENFEILNDEVYVGPRKEFFELETEKLVPLYDLFFKNVEDEISENEKIITIDVPKHLRETEVELLAAETKGVRGNNFVGIIKEKSLFIYPKDELIGKHGIVKFKGEIIYTGVISETLVIENTEGLVIQNIEKDLIIEVI
>NZ_CP007389.1|WP_012057870.1|1654971_1656405_+|SAVED-domain-containing-protein
MFGNLLKNDPDSFIELLNSDQIHLDEAIKSYLKNKDFKAKERIFYEIVKKMYLKKVKNISEELLSKFFDGNIELVFDLLKNGYVEAKFPIVKEEYGKIARVMVIKSENSFSNVKLNKLRVIENVVGHRLAVIFDSKFVGNSFMLATALAALTSKIPINLAFSGEIDEEGVIKKNLDGFSIKERVCSENNLKLIGAFDVSNVFELKEFFEEENFHIPVLMFFRKEEEEYINFSYEKLFKSVSKKYPVRFAELFEKVYDVKKFFVTNELSSLEKWKKALKEAKAFLLKIISNGGIPHVAIVGPSAMAMALGIAIGLQNPLVIYHKQDEYYPVIDLTDNLRKIKNIKDSYEYLKYTTFDEGKDCAYVIYLASHNPFSSVIKFLENNSLDSKIILIEPIENKGNLSIDTWGKIVSELMSITQNVLYDNYCENVFFFLSCPVAIALGFGMAFGDFAKGGIFHYNKADDSYIEVFKIERIRGD
>NZ_CP007389.1|WP_077277097.1|1656355_1657813_+|TIGR01897-family-CRISPR-associated-protein
MILILKFLKLKGLGGIRLKVLFAIVGNLKTFREKKYRLNLEDQHSELICDSSLQLLSEYYNVDKTVIFLPDTLYTTCDINKIPSSYDELTKLLAEEYDKKIRKKLKINNFEIVIVPGIGTYKLGDGNLVFDGEIKDLYNFSLYKLYKLLLEKEFLNGEKVEFIFDISTGLNYHQSVISSVLNDLLKLLAYLKDTSLTIVNSEPITDLKEVLNVYIIDQKKIFPGIEIQKIKRHKILEVFPYLSNEEKRYYGLKFMKNLEQIILNKSGNKKIMEFFNMVLYFLNSLVYGLPLVLLYFNKKLKSNEIIEKSVKFFLEAIEIENNHVFRKLKFGEFFKYVVFAELFKEYFNNVIDDYNTDKIPFEILEETSEKVWKVKEPSSDLNVNAFISLSIKKELYEIKNSFLENIGEGQEVVFTKGPNKGTDTQKFNNASNKYDKTVNHDPRRNFLAHSGLSSGSFKLKKENDHLYISAIEDKIKKFLGILLKS
>NZ_CP007389.1|WP_012057872.1|1657825_1660099_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MINLSVEKVFLAGIFHDIGKFYIRANFGDLKKNIYEEYKYFIEGDNKYGPRHQEWGAYFYKNSNLPFKDEIEGAILNHHKPNSVLSKLISVADHISATEREGEHPEDKVKNMKSMLSMVSFSNDQKKGKYKKVSKLSEKFDLLEKEDENVEETYKNLWREFEKVINSIPRNKNPKISFPIFEKIYYILKEYTSNIPSAFFYNEPDISLFSHLSTTAGIAVAIFKQFEEEIKLGNIKILENIDSKNYDEKILGIVKGDISGIQDFLYNISQERAVKKLRGRSFYITYLLEIVAKYIIENEGLSISNILFNGGGHFYLIVPAKTIDKLEKYQKYIDEVMYKAHGIGLNINIAGEKIAPKELNSEIYKRVSQLVERKKYTKLYSLISYDFHKIFESKNLSEDSCPYCRRKMKDDECTFCESFTVIGDRLSKRKAFKLNKTEKIPEKINTYEDVFKMFGYEVEFEEGPFSFLIDKSGNVDLSRYMFYTKSANYISKKENNEISDLETIAKNSNGMEKWGVLRGDVDNLGRIFKEGLGKEASISKTATLSQEIEIFFGKFLEDIVSNEFSNCTVIYSGGDDFFIIGPWSDLPNLAENIQKEFKRYSGDNECISISMGIGISPAKKYPVYRVAKLAGEYLEKAKEYERKGIEKSALGFLGDFIGWEEFEEYKYFKNKLTDLINEKITKRILHVLRRYYQEYDENEGTNKVWKLYYYFAQLSDRYSKSKDKILKFLSEILKDDNKLYNKIYSLTYWVEYELKEG
>NZ_CP007389.1|WP_012057873.1|1660100_1660541_+|type-III-A-CRISPR-associated-protein-Csm2
MRNDNFSRQRNSQKEFINQELAEKILNPDSDPDGENLFEYSKEISKEIKVLSSTQLRKYYDEVKKIPNNKDYKYHLKRFIAVFLYSVNKIKNKKNKEVVEKFSESIKNLALVASNNDERYFKRFRDFFEALVAYHTYYKNNNNNKE
>NZ_CP007389.1|WP_012057874.1|1660557_1661367_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MVNLEFKGKIIVKADIHVVTGLQIGKENSMEIGGIDNPVIKDSLGKPYIPGSSLKGKLRTLMEYFHGKIKNDVLVVAKGGENQIRIHQCDEKDCPVCNLFGRNHGKHRYASNPDVEVEFKNIMPTRLFVRDALLDENSITEEMKKNLDNEFTEVKPENTLDRITSAANPRFNERVPAGAIFKSEFVINVYDDDNEKYLRELLTALSLLEDDYLGGSGSRGYGKVRFENIKIVYKGKGYYDGSNKELPKKELDDLNNWEEKIKDFKLNGD
>NZ_CP007389.1|WP_012057875.1|1661371_1662313_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MKNYRIRLKFKSPLHVGQVDKVETVVSDIIHSDTIFSAIINSYNLLYGKEKTKELLKFILENEDSILISSAFYYYNDIYFYPRPLGYKFDLDKKFDFKKVKKIKFVSEEYITGKVKTPIIINGLATDNKEIERLYFIEERPRITVDRITNETNIFYVSALRFIENSGLWFFLSLSEEIEREIFAALRLLSDEGLGGDRTHGNGNFDFDVEKVDFGRFQGDNCLLLSVYYPKNQNEIDSTLSYKLYERSGYVYSQYSMSYKQPLVRLFAEGSVFKNKVTGDVLDITPIGFEYHKVFKFARAYTIPIKKEAQYDI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_CP020005	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence	69567-69600	7	0.794
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NC_015915	Borreliella bissettii DN127 plasmid lp17, complete sequence	23144-23177	7	0.794
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_CP020005	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence	69567-69600	7	0.794
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NC_015915	Borreliella bissettii DN127 plasmid lp17, complete sequence	23144-23177	7	0.794
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	MN693770	Marine virus AFVG_250M115, complete genome	29873-29906	8	0.765
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_MK275619	Clostridium perfringens strain JXJA17 plasmid p1, complete sequence	15616-15649	8	0.765
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_CP007768	Campylobacter peloridis LMG 23910 plasmid pPEL2, complete sequence	3546-3579	8	0.765
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	MN693029	Marine virus AFVG_117M56, complete genome	20832-20865	8	0.765
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	MK496717	Capybara microvirus Cap1_SP_127, complete genome	5001-5034	8	0.765
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	MN693770	Marine virus AFVG_250M115, complete genome	29873-29906	8	0.765
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_MK275619	Clostridium perfringens strain JXJA17 plasmid p1, complete sequence	15616-15649	8	0.765
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_CP007768	Campylobacter peloridis LMG 23910 plasmid pPEL2, complete sequence	3546-3579	8	0.765
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	MN693029	Marine virus AFVG_117M56, complete genome	20832-20865	8	0.765
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	MK496717	Capybara microvirus Cap1_SP_127, complete genome	5001-5034	8	0.765
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_CP040614	Campylobacter sp. CFSAN093246 plasmid unnamed, complete sequence	5811-5844	9	0.735
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_CP048772	Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence	72734-72767	9	0.735
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_CP040614	Campylobacter sp. CFSAN093246 plasmid unnamed, complete sequence	5811-5844	9	0.735
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_CP048772	Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence	72734-72767	9	0.735
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_CP044539	Borrelia sp. CA690 plasmid cp26, complete sequence	19985-20018	10	0.706
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_CP044539	Borrelia sp. CA690 plasmid cp26, complete sequence	19985-20018	10	0.706
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_CP017256	Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence	81351-81384	11	0.676
NZ_CP007389_3	3.50\|757855\|34\|NZ_CP007389\|CRISPRCasFinder,CRT	757855-757888	34	NZ_MG205643	Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence	71659-71692	11	0.676
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_CP017256	Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence	81351-81384	11	0.676
NZ_CP007389_3	3.105\|757856\|34\|NZ_CP007389\|PILER-CR	757856-757889	34	NZ_MG205643	Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence	71659-71692	11	0.676

1. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_CP020005 (Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.794

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
atattttaaatatttataaatttgatgctataaa	Protospacer
.********** *********** ***** .. *

2. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NC_015915 (Borreliella bissettii DN127 plasmid lp17, complete sequence) position: , mismatch: 7, identity: 0.794

gtattttaaatttttataaatttta----tgcttcgca	CRISPR spacer
ctattttaattttttataaatattaattttgctt----	Protospacer
 ******** *********** ***    *****

3. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_CP020005 (Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.794

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
atattttaaatatttataaatttgatgctataaa	Protospacer
.********** *********** ***** .. *

4. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NC_015915 (Borreliella bissettii DN127 plasmid lp17, complete sequence) position: , mismatch: 7, identity: 0.794

gtattttaaatttttataaatttta----tgcttcgca	CRISPR spacer
ctattttaattttttataaatattaattttgctt----	Protospacer
 ******** *********** ***    *****

5. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to MN693770 (Marine virus AFVG_250M115, complete genome) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtattttaaagttttataaattttagggaggtta	Protospacer
********** ************** *     .*

6. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_MK275619 (Clostridium perfringens strain JXJA17 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtcttttaaatttttataatttttaggtatatta	Protospacer
** **************** ***** *. *  .*

7. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_CP007768 (Campylobacter peloridis LMG 23910 plasmid pPEL2, complete sequence) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattt----tatgcttcgca	CRISPR spacer
gttttttaaatttttttaaattttttatatattt----	Protospacer
** ************ *******    ***..**

8. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to MN693029 (Marine virus AFVG_117M56, complete genome) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
taattttaaatttgcataaattttatttttagaa	Protospacer
  *********** .*********** .** * *

9. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to MK496717 (Capybara microvirus Cap1_SP_127, complete genome) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaatttt-----atgcttcgca	CRISPR spacer
gttttttaaatttttataaatgtttttaagtgct-----	Protospacer
** ****************** **     .****

10. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to MN693770 (Marine virus AFVG_250M115, complete genome) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtattttaaagttttataaattttagggaggtta	Protospacer
********** ************** *     .*

11. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_MK275619 (Clostridium perfringens strain JXJA17 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtcttttaaatttttataatttttaggtatatta	Protospacer
** **************** ***** *. *  .*

12. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_CP007768 (Campylobacter peloridis LMG 23910 plasmid pPEL2, complete sequence) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattt----tatgcttcgca	CRISPR spacer
gttttttaaatttttttaaattttttatatattt----	Protospacer
** ************ *******    ***..**

13. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to MN693029 (Marine virus AFVG_117M56, complete genome) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
taattttaaatttgcataaattttatttttagaa	Protospacer
  *********** .*********** .** * *

14. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to MK496717 (Capybara microvirus Cap1_SP_127, complete genome) position: , mismatch: 8, identity: 0.765

gtattttaaatttttataaatttt-----atgcttcgca	CRISPR spacer
gttttttaaatttttataaatgtttttaagtgct-----	Protospacer
** ****************** **     .****

15. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_CP040614 (Campylobacter sp. CFSAN093246 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
aaatttttaatctttataaattttatttttttta	Protospacer
. ***** ***.************** .**. .*

16. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_CP048772 (Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence) position: , mismatch: 9, identity: 0.735

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
aaatttttaatctttataaattttatttttttta	Protospacer
. ***** ***.************** .**. .*

17. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_CP040614 (Campylobacter sp. CFSAN093246 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
aaatttttaatctttataaattttatttttttta	Protospacer
. ***** ***.************** .**. .*

18. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_CP048772 (Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence) position: , mismatch: 9, identity: 0.735

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
aaatttttaatctttataaattttatttttttta	Protospacer
. ***** ***.************** .**. .*

19. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_CP044539 (Borrelia sp. CA690 plasmid cp26, complete sequence) position: , mismatch: 10, identity: 0.706

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtatttttaatttttaaaaattttttattctttt	Protospacer
******* ******** ******* *..*.. .

20. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_CP044539 (Borrelia sp. CA690 plasmid cp26, complete sequence) position: , mismatch: 10, identity: 0.706

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtatttttaatttttaaaaattttttattctttt	Protospacer
******* ******** ******* *..*.. .

21. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_CP017256 (Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence) position: , mismatch: 11, identity: 0.676

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtagttttaatttttataaattttgattaatata	Protospacer
*** *** ****************.  .  ...*

22. spacer 3.50|757855|34|NZ_CP007389|CRISPRCasFinder,CRT matches to NZ_MG205643 (Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence) position: , mismatch: 11, identity: 0.676

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
ttattttaaaattttttaaattttaactaattta	Protospacer
 ********* **** *********  .  . .*

23. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_CP017256 (Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence) position: , mismatch: 11, identity: 0.676

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
gtagttttaatttttataaattttgattaatata	Protospacer
*** *** ****************.  .  ...*

24. spacer 3.105|757856|34|NZ_CP007389|PILER-CR matches to NZ_MG205643 (Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence) position: , mismatch: 11, identity: 0.676

gtattttaaatttttataaattttatgcttcgca	CRISPR spacer
ttattttaaaattttttaaattttaactaattta	Protospacer
 ********* **** *********  .  . .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

44468 : 52322

Staphylococcus_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012056282.1\|44468_45089_+	sigma-70 family RNA polymerase sigma factor	A0A218KDH9	Bacillus_phage	3.0e-05	25.7
WP_012056283.1\|45675_46128_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.1e-28	46.7
WP_012056284.1\|46124_47246_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.1e-74	42.9
WP_012056285.1\|47223_47790_-	riboflavin synthase	A0A1V0SE20	Indivirus	4.7e-21	40.4
WP_143610947.1\|47782_48802_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.7e-42	34.5
WP_012056287.1\|48974_50666_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.3e-13	45.5
WP_012056288.1\|50683_51091_-	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_012056289.1\|51080_52322_-	SufS family cysteine desulfurase	Q2XUY6	environmental_halophage	8.0e-82	39.2

DBSCAN-SWA_2

162597 : 173762

Tupanvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012056389.1\|162597_163449_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.7e-20	30.1
WP_012056390.1\|163445_164423_-	ABC transporter permease	NA	NA	NA	NA
WP_012056391.1\|164415_164955_-	macro domain-containing protein	A0A0U1WHI4	BtRf-BetaCoV/SX2013	2.0e-13	36.6
WP_012056392.1\|164938_166171_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.0e-65	38.1
WP_012056393.1\|166139_167072_-	SDR family NAD(P)-dependent oxidoreductase	A0A2K9L4U8	Tupanvirus	3.3e-48	36.4
WP_012056394.1\|167071_167575_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_012056395.1\|167564_168167_-	uracil-DNA glycosylase	S5M974	Bacillus_phage	8.2e-24	36.2
WP_012056396.1\|168368_171014_+	pyruvate, phosphate dikinase	H8YJB7	Vibrio_phage	1.6e-92	41.3
WP_012056397.1\|171071_171482_+	hypothetical protein	NA	NA	NA	NA
WP_012056398.1\|171478_172831_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A0N7G7P8	Chrysochromulina_ericina_virus	3.4e-33	38.8
WP_012056399.1\|172811_173762_+	ribose-phosphate pyrophosphokinase	A0A2K9L8D8	Tupanvirus	1.9e-43	34.6

DBSCAN-SWA_3

396905 : 405136

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012056611.1\|396905_397349_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	3.3e-22	39.7
WP_012056612.1\|397349_398447_-	ABC transporter permease	NA	NA	NA	NA
WP_012056613.1\|398451_399621_-	hypothetical protein	A0A223LDP1	Bacillus_phage	1.0e-09	23.5
WP_012056614.1\|399607_400243_-	hypothetical protein	NA	NA	NA	NA
WP_012056615.1\|400308_401217_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FZ01	Synechococcus_phage	4.1e-35	33.0
WP_012056616.1\|401213_402401_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_012056617.1\|402410_403304_-	phosphoribosylaminoimidazolecarboxamide formyltransferase	Q58MG4	Prochlorococcus_phage	1.1e-37	34.1
WP_012056618.1\|403319_403877_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-27	40.7
WP_012056619.1\|403840_405136_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.2e-41	31.0

DBSCAN-SWA_4

539811 : 547383

uncultured_Mediterranean_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012056734.1\|539811_540771_+	radical SAM protein	A0A1B1ITW6	uncultured_Mediterranean_phage	3.8e-07	20.8
WP_012056735.1\|540767_541766_+	radical SAM protein	A0A1B1IVD8	uncultured_Mediterranean_phage	2.2e-29	28.7
WP_155760982.1\|541755_543648_+	asparagine synthase (glutamine-hydrolyzing)	A0A2K9L187	Tupanvirus	3.5e-28	28.1
WP_012056737.1\|543660_544800_+	dTDP-4-amino-4,6-dideoxygalactose transaminase	A0A2P1ELT3	Moumouvirus	8.2e-33	28.6
WP_012056738.1\|544803_545460_+	formyl transferase	M4QRX9	Synechococcus_phage	1.3e-06	27.6
WP_012056739.1\|545477_546350_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.0e-103	63.5
WP_012056740.1\|546363_547383_+	dTDP-glucose 4,6-dehydratase	A0A1D8EQC0	Escherichia_phage	4.3e-73	44.4

DBSCAN-SWA_5

1241872 : 1250648

Erysipelothrix_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012057441.1\|1241872_1243213_+	SidA/IucD/PvdA family monooxygenase	A0A2K5B2C5	Erysipelothrix_phage	3.5e-14	23.5
WP_143611075.1\|1243515_1244016_+	serine acetyltransferase	NA	NA	NA	NA
WP_012057443.1\|1244028_1244886_+	cysteine synthase family protein	A0A1W6JHY1	Lactococcus_phage	4.0e-64	49.8
WP_012057444.1\|1245092_1245545_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.9e-29	50.7
WP_012057445.1\|1245558_1246245_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.6e-39	39.3
WP_012057446.1\|1246220_1246469_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_012057447.1\|1246465_1247098_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_012057448.1\|1247094_1248867_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.9e-89	34.9
WP_041426050.1\|1249028_1250648_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	6.1e-05	22.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007389

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection