CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP019304	Arthrobacter sp. QXT-31 chromosome, complete genome	3 crisprs	csa3,DinG,cas3,DEDDh,WYL	0	6	1	0

1. NZ_CP019304

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP019304_1

• CRISPR_ID: NZ_CP019304_1
• CRISPR_location: 619457-619554
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP019304_1

Consensus_repeat	Method
CGGGGCATGCCCTGGGACGTGGC	CRISPRCasFinder

spacers of NZ_CP019304_1

>1.1|619480|52|NZ_CP019304|CRISPRCasFinder
AAACGGGTTGTTGCCCGGGCGCGGCGGACGTTCGCCGTCTCCTCCGCGGCCG

CRISPR arrays and Neighbor proteins around NZ_CP019304_1

CRISPR arrays

The CRISPR arrays of NZ_CP019304_1

>merge|NZ_CP019304|1|619457-619554|CRISPRCasFinder
CGGGGCATGCCCTGGGACGTGGCAAACGGGTTGTTGCCCGGGCGCGGCGGACGTTCGCCGTCTCCTCCGCGGCCGCGGGGCATGCCCTGGGACGTAGC

>NZ_CP019304|1|1|619457-619554|CRISPRCasFinder
CGGGGCATGCCCTGGGACGTGGC	AAACGGGTTGTTGCCCGGGCGCGGCGGACGTTCGCCGTCTCCTCCGCGGCCG
CGGGGCATGCCCTGGGACGTAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019304.1|WP_172804237.1|609449_610613_+|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|223513
NZ_CP019304.1|WP_076798157.1|616360_616870_-|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl|CDD|234787
NZ_CP019304.1|WP_076798149.1|606802_607513_+|DUF937-domain-containing-protein	unknown	unknown	gnl|CDD|227690
NZ_CP019304.1|WP_076798160.1|620767_621745_-|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl|CDD|237061
NZ_CP019304.1|WP_076798164.1|625672_627109_-|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|223154
NZ_CP019304.1|WP_076798167.1|630110_630998_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379120
NZ_CP019304.1|WP_157365087.1|611276_612017_-|HNH-endonuclease	unknown	unknown	gnl|CDD|238038
NZ_CP019304.1|WP_076798161.1|621744_622362_-|ribosome-maturation-factor-RimP	unknown	unknown	gnl|CDD|234627
NZ_CP019304.1|WP_083706203.1|622467_623766_+|DUF4439-domain-containing-protein	unknown	unknown	gnl|CDD|373114
NZ_CP019304.1|WP_076803469.1|615136_616258_+|ScyD/ScyE-family-protein	unknown	unknown	gnl|CDD|380207
NZ_CP019304.1|WP_076798163.1|624627_625668_+|aminoglycoside-resistance-protein	unknown	unknown	gnl|CDD|309685
NZ_CP019304.1|WP_076798165.1|627169_627964_-|TSUP-family-transporter	unknown	unknown	gnl|CDD|182593
NZ_CP019304.1|WP_076798166.1|627976_629788_-|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236405
NZ_CP019304.1|WP_172411749.1|608350_609352_-|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl|CDD|235113
NZ_CP019304.1|WP_076798162.1|623809_624553_+|VIT-family-protein	unknown	unknown	gnl|CDD|153123
NZ_CP019304.1|WP_157365086.1|607537_607975_-|hypothetical-protein	unknown	unknown	gnl|CDD|130543
NZ_CP019304.1|WP_157365088.1|612032_612800_-|DUF222-domain-containing-protein	unknown	unknown	gnl|CDD|367155
NZ_CP019304.1|WP_076798154.1|610655_611141_-|nucleoside-deaminase	unknown	unknown	gnl|CDD|238612
NZ_CP019304.1|WP_076798151.1|607994_608348_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019304.1|WP_076798159.1|620186_620528_-|YlxR-family-protein	unknown	unknown	gnl|CDD|377288

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019304.1|WP_172804237.1|609449_610613_+|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|223513	COG0436, COG0436, Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism].	2.05225e-117
NZ_CP019304.1|WP_076798157.1|616360_616870_-|30S-ribosome-binding-factor-RbfA	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	1.37209e-46
NZ_CP019304.1|WP_076798149.1|606802_607513_+|DUF937-domain-containing-protein	gnl|CDD|227690	COG5403, COG5403, Uncharacterized conserved protein [Function unknown].	7.56325e-16
NZ_CP019304.1|WP_076798160.1|620767_621745_-|transcription-termination/antitermination-protein-NusA	gnl|CDD|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	0
NZ_CP019304.1|WP_076798164.1|625672_627109_-|aspartate-aminotransferase-family-protein	gnl|CDD|223154	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism].	4.19586e-58
NZ_CP019304.1|WP_076798167.1|630110_630998_-|GNAT-family-N-acetyltransferase	gnl|CDD|379120	pfam13312, DUF4081, Domain of unknown function (DUF4081). This domain is often found N-terminal to the GNAT acetyltransferase domain, pfam00583 and FR47, pfam08445.	8.35238e-35
NZ_CP019304.1|WP_157365087.1|611276_612017_-|HNH-endonuclease	gnl|CDD|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	4.39944e-10
NZ_CP019304.1|WP_076798161.1|621744_622362_-|ribosome-maturation-factor-RimP	gnl|CDD|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	1.16094e-33
NZ_CP019304.1|WP_083706203.1|622467_623766_+|DUF4439-domain-containing-protein	gnl|CDD|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	7.00531e-16
NZ_CP019304.1|WP_076803469.1|615136_616258_+|ScyD/ScyE-family-protein	gnl|CDD|380207	NF033206, ScyE_fam, ScyD/ScyE family protein. This family includes ScyE, a protein involved in scytomenin biosynthesis and export, and its paralog ScyD. Some members of the family contain a C-terminal PEP-CTERM domain that predictions anchoring to the outer membrane.	1.2167e-71
NZ_CP019304.1|WP_076798163.1|624627_625668_+|aminoglycoside-resistance-protein	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	1.90834e-19
NZ_CP019304.1|WP_076798165.1|627169_627964_-|TSUP-family-transporter	gnl|CDD|182593	PRK10621, PRK10621, hypothetical protein; Provisional.	3.15306e-42
NZ_CP019304.1|WP_076798166.1|627976_629788_-|proline--tRNA-ligase	gnl|CDD|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NZ_CP019304.1|WP_172411749.1|608350_609352_-|tRNA-pseudouridine(55)-synthase-TruB	gnl|CDD|235113	PRK03287, truB, tRNA pseudouridine synthase B; Provisional.	9.95495e-162
NZ_CP019304.1|WP_157365086.1|607537_607975_-|hypothetical-protein	gnl|CDD|130543	TIGR01478, Plasmodium_falciparum, variant surface antigen, stevor family. This model represents the stevor branch of the rifin/stevor family (pfam02009) of predicted variant surface antigens as found in Plasmodium falciparum. This model is based on a set of stevor sequences kindly provided by Matt Berriman from the Sanger Center. This is a global model and assesses a penalty for incomplete sequence. Additional fragmentary sequences may be found with the fragment model and a cutoff of 8 bits.	0.00123027
NZ_CP019304.1|WP_157365088.1|612032_612800_-|DUF222-domain-containing-protein	gnl|CDD|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	0.000289847
NZ_CP019304.1|WP_076798154.1|610655_611141_-|nucleoside-deaminase	gnl|CDD|238612	cd01285, nucleoside_deaminase, Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on the substrate. The functional enzyme is a homodimer. Cytosine deaminase catalyzes the deamination of cytosine to uracil and ammonia and is a member of the pyrimidine salvage pathway. Cytosine deaminase is found in bacteria and fungi but is not present in mammals; for this reason, the enzyme is currently of interest for antimicrobial drug design and gene therapy applications against tumors. Some members of this family are tRNA-specific adenosine deaminases that generate inosine at the first position of their anticodon (position 34) of specific tRNAs; this modification is thought to enlarge the codon recognition capacity during protein synthesis. Other members of the family are guanine deaminases which deaminate guanine to xanthine as part of the utilization of guanine as a nitrogen source.	7.41051e-40
NZ_CP019304.1|WP_076798162.1|623809_624553_+|VIT-family-protein	gnl|CDD|153123	cd02432, Nodulin-21_like_1, Nodulin-21 and CCC1-related protein family. Nodulin-21_like_1: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter. .	5.38114e-98
NZ_CP019304.1|WP_076798159.1|620186_620528_-|YlxR-family-protein	gnl|CDD|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	3.13055e-25

Protein sequences

>NZ_CP019304.1|WP_076798157.1|616360_616870_-|30S-ribosome-binding-factor-RbfA
MADPARAAKMAQRIKVVVAEALGRKVKDPRLEGITVTDARVTNDLQHATVYYTVFGDQAVQADAAKGLEKAKGVLRQEVGRNITARLTPTLEFVADQIPVNASNLEELLRTAKQRDAEVAELARNAKHAGEADPYKSDVQPDVEIDEDDFDEEDLDLVDGDSIDEDRNH
>NZ_CP019304.1|WP_076803469.1|615136_616258_+|ScyD/ScyE-family-protein
MEKQRAFLAAVAAAALLLSASPAGHAAPAGDAKGSQPAPVVLAKGLLSPLHLSDGQDGSVLVSEEFAGRLTKIARDGSKSVVYRDAAWDVAGTDRRGRTIYIAESQGAGPMDPRPLAGHIRSIDADGKQRTFGDLAALETKHNADGGTSFGFKNLPAACAAKLPKDVPISYKGQIDSHPYGIDVYGSTIYVADAGANSIVSVDVKSGEAETVAVLPARPHTFTAAEAAALKLPGCIVGHTYRFEPVPTDVKRGPDGWLYVSVLPGGPEDPALGARGAVFKINPDNGRVKLFADDVMSPTGVDMDDDGHVYVASLFGKGVLRLSAHSGKQTVVLPGVLTADVDIRGETVYATVNSLPVPNAAPDGRVVKMPLDD
>NZ_CP019304.1|WP_157365088.1|612032_612800_-|DUF222-domain-containing-protein
MTAVERLSRRVEHLQVVAAGAVERSRTAALTAAAAPLVPDAVPVPDADPNADGSRNTVDFLRTRLGISACEARRRLTLADSILPRAGFGGQQLPPRYGELATAVSTAQVSSRAATTITLALDRARHFTTPARTAAMEHELTQTAIDNDADFVTRVARHWAEAIDQDGPEPSEPALRQIQGAFIRRPKHGLHHLEIFATPEQFETLTTAMNTATNPRTPAPEHADGNGSDGDGGNGSHGAGGGTARRRRDQRGGGC
>NZ_CP019304.1|WP_157365087.1|611276_612017_-|HNH-endonuclease
MGQPGCTGNRPGSPVAGAETPRRARRRLPNRPHHRRPARQRRHRPQILVTIDYRDLLARVEQWLGQPSTASLQGALDTQWAQGDQDLQPASAGPLNAARTGDGTALFAFSGPVNPATIRKIACDADLIPVVLGTGGRILDVGRASRIFPPHIRKAIMARDQGCAFPQCTMPAPWCEAHHITYWSRGGPTSTANGVLLCSYHHHLIHKENWTIEVTNEVPWFKPPPELDRGRKPRRNQYFRSRPHRE
>NZ_CP019304.1|WP_076798154.1|610655_611141_-|nucleoside-deaminase
MRAHPSAADVTGYLTEAVALAERNVAAGGGPFGALVVTADGTVHEGVNRVTRDNDPTAHAEVVAIRTAAAETKNFDLSGAVLYASCEPCPLCLAAALWARIDRVYFAADRHGAAAAGFDDAVFYEYFDGSRPELLPVSHTPVPTSGSPFDAWRSNAERTNY
>NZ_CP019304.1|WP_172804237.1|609449_610613_+|pyridoxal-phosphate-dependent-aminotransferase
MPELSAHIRDVPVNQIREITEAAWRTPGALILSIGEPGFPLPRHVLDAGIACLDRDETNYTPNAGFPALREAFAARFRELSGADIGADRVYVVDGAQQGLHFAMSLLLAPGDEILIPNPGYPTFAMTSRLLHAVPVQYPLYPAHDFQPRIADIEALITDRTRVLVLNSPSNPLGAVLREDLTRELVELARRHDLWIISDECYEAFTYDVPHVSPARFDSTVPGEARVFTSLTLSKTYGLTGLRIGALVCPPGLEQRMNNVMEAIVSCVASPSQYAALAALTGPQDYVSQAHAHYRANRDAASAVLAEKGIPFLSAQGAFYLWADVSHVSGGNVRAWVKQFLADAGVSFAPGTAFGSIGEGWIRIALCGDQRELVEGVGRLPRRHPAP
>NZ_CP019304.1|WP_172411749.1|608350_609352_-|tRNA-pseudouridine(55)-synthase-TruB
MVIVDKPQGWTSHDVVGRMRRIAGTRKVGHAGTLDPMATGVLVLGINKATRLLTYIVGTSKTYTATIRLGESTITDDAEGEVVSRTSAASLTEDAIRSGVDSLTGEIQQVPSSVSAIKVNGERSYARVRSGEDVQLAARPVTIHRFDIHEIRRDHAAGHDTDVVDIDVTVECSSGTYIRALARDLGNSLGVGGHLTALRRTNVGPYSLDQARTLEQLAEDLEVLEMSQAARALMPNRELSADETTEISFGRRIAAGAAAGTPGAATAEKPAAAFAPDGSLVALLADSGSFAKPVLVFAPGTGPGVSNSSGASSSSDAGAGVPNGSRADSGGRA
>NZ_CP019304.1|WP_076798151.1|607994_608348_-|hypothetical-protein
MDAFFYIILGVGLLSTIICVAAGIMKKAPNDITILSVAAVELALLIYLLGSIVRVIAGEQIAGEAWEFWGYLATALLLPVAAVYWSILERTRWSNFVLAAVGVTALVMAARMNQIWY
>NZ_CP019304.1|WP_157365086.1|607537_607975_-|hypothetical-protein
MTETSEHTGQRPGNTRNTGPGRLLIAVYAIFAISATARAGYQILTKFSEAPLAYLLSAFAAVVYVVATVSLAKAGRTWFKVSLVAVLVELVGVIIVGALSLFDAVQFPHETVWSAFGRGYAFVPLILPVLGLIWLYRRRPSAPAV
>NZ_CP019304.1|WP_076798149.1|606802_607513_+|DUF937-domain-containing-protein
MSDIQELLGQIPVQQIASMLGTDTASAQAAVEAAVPTLLAGMQSNVQAPDGAAALESQLARHRNGLADGGVDPSQVDTQDGEKIVGHVFGGQQDQVANRLAGTANLGGVGGDLVRRLLPILAPIVMSYLAKKVLGGGQGSAGQTSPAGGIDLGSILGGILGGGLGSGGPGPGGPGGGHGSGGLGDILGGILGGGPQPRQSPPAAQGVEPGTLPAPTGPRTVTPGELIEVDLPDENR
>NZ_CP019304.1|WP_076798159.1|620186_620528_-|YlxR-family-protein
MAHVQHVGNQPQRTCIGCRKKGPRSELLRLVSDAGGSSAVVVDERRRMAGRGAWLHPSEACLALAVKRRAFGRALNGSTGTAAVERRITAGAHAADVPASAVPTVQPESGSEI
>NZ_CP019304.1|WP_076798160.1|620767_621745_-|transcription-termination/antitermination-protein-NusA
MDIDMSALRLLEREREIPLDLLIPTIEQALLVAYHKSPGAFEKARAELDRKSGHVTIWATEIDDDGAPIGEFEHTPAGFGRIAASTARQIILQRLRDVEDDNVLGEFKGREGELVAGLIQQGNNPHMIQVNLGTVEALLPPPEQVPGEKYIHGNRLRAYVIDVHRGTKGPSITLSRSHPGLVRKLFELEVPEIADRSVEIVALAREAGHRTKIAVKANTPGINAKGACIGEMGSRVRAVMTELNDEKIDIVDFSEDPATFIASALSPSRVNSVTITDEATRSARVVVPDYQLSLAIGKEGQNARLAAKLTGWRIDIVSDAAAPRG
>NZ_CP019304.1|WP_076798161.1|621744_622362_-|ribosome-maturation-factor-RimP
MSNAEATTSSDRTGAGKAEAAAVHNPEAERLRSLLEPAVQSHRLYLEDVAIQIAGSNRIVHVVVDLPQEETGGVSLDVIADISKELSDILDNDPGTDSRPYDLEVSSPGVGRPLTEPRHWHRARGRMVTVNVIQDENVTGRISSVDDAGVTIVPEIAVKKGMKPRQGDPVKLPFDKIRSGKVEIEFSRLDEAGLETEHNGPSEEA
>NZ_CP019304.1|WP_083706203.1|622467_623766_+|DUF4439-domain-containing-protein
MNDDSGRKRRPGNYLRYALLALAAFLVLSLGFALIPRESPAPAAPSFSEQARTAALAETLDLRAASQQLANGSSGARRQLFSHAVTLLTTQARALLLPGGDTSSPAVGTGSAPGASSAAGASGTAGPSAGAPGTASASAGATSAPAPSGTAALPALVTALSKSGKERLLHAEKADGGMARLLTAVGTAQLLQATTLAQAAGTPPPALPAPSATQRNAATACSVTSPSGSGARSQDGAQSSSSDQSNNSDPSSSSGQSSGSDQSGQTTGPADTATLAAALGRAVRTEVETVYGYQVALTRLEGAAAEQAAGLLAKHEAVVGQAEAYTRVHCVSVPPREPGYTLDTSFLQKPAAGLASLEAGTLPVYGDLVALSDGETRKWAVSSLVAAAQRTMRWGSDPGPVPGIVLDTSLLPELPEPAAPSAHPTGDGTATP
>NZ_CP019304.1|WP_076798162.1|623809_624553_+|VIT-family-protein
MESADNPALPPAGQHANEPHSNDIVHRLNWLRAGVLGANDGIVSVAAIVVGVAGATSEHGPILAAGAAGLVGGAVSMALGEYVSVSSQSDSQKAMIEKERRELAEEPEEELTELAAIYRSKGLSEETARNVARELTEHDALAAHLSAELNIDEEDIVSPWHAAFASAIAFTLGALLPMLAIMLPPENIRVAVTFGAVLLALAVTGAVGAWIGGGSKIRAAARVVVGGGLALAATFTIGNLLGATGIM
>NZ_CP019304.1|WP_076798163.1|624627_625668_+|aminoglycoside-resistance-protein
MSPPADVPIPPDLMRRYSRNSAGRAWLASLPDMIRGRLDQWQLELDLEPGTLPWSGHGGVVVPVRAAGVAAALKVAFPHDEALVERHALALWDGHGAVQLLASDAGTCSMLLERLDAGRSLRTEPMDTALEVWGRLMRELSLVPDGRPQWQEFVHVAARAEQWSDDLPAEWEQLGRPFPRWLLEAALEVCQTRGAVGRRSSDDVLVNTDFHYLNILARLDERGSAAATGFAAIDPQPMVGEAEFAVAPVLWNRIPDLPARDPAAGLLARCHDFSVAAGLDPEVARQWSLAREVDNALHYTSRPGHGGDMARSLWVASTLAGRTLDGLPAAHDLPEPGEDALDSAPT
>NZ_CP019304.1|WP_076798164.1|625672_627109_-|aspartate-aminotransferase-family-protein
MSAGAEPYREALAAAVRHATLWLESQSTRRVGPQQAARELAAAFDGALPQSGMAPAAVVDYLARHAEPGLMAMPSGRFFGWVIGGTLPAAMAADWLVSAWDQNSVLRYATPAIAAIEDAAGHWLLQLLGLPEESDVGFVTGATMANFTGLAAARWRLLKNAGWDLERDGLFGAPRIHCLVGKERHETVDVALRYLGMGSPTVVPADSQGRIEAAELDCALDRIALDHAAASGQSSPPALVLVCLQAGNLHSGAFDPFGAAIAVSKAHGAWVHVDGAFGLWAAAVPELAGLTAGVEGADSWATDAHKSLNVPYDCGVVAVRDAQALRSAMGLNASYLLQDVDGAGHPSQRVPELSRRARGVPVWAALKSLGRDGVAEQIRRLAASAAQLAEELTAVEGVEVLNDVGYTQITVAFGDDAMTRRVADRLIADGKVWMSGSRWHGRDVVRISVSNWSTDAGDLATAVDAVRTALEAARSERS
>NZ_CP019304.1|WP_076798165.1|627169_627964_-|TSUP-family-transporter
MVSGFESIQLATIVLIVVAGFSAGWVDAVVGGGGLLQLPALLLVPGITPVQALATNKMGSIFGTTTSAVTYYGRVRPDLRTAVPMAAIALAGSFGGALLATRLPAEVFKPIIVVALVAVALFTALKPDAGHLTELRHDGRTHYVVACAIGAVIGFYDGLIGPGTGSFLVIALVSAMGYAFLEASAKAKIVNMATNAGALIFFLPHGSLLWGVGLLLGAANMAGGYLGARTAVKQGSKFVRVVFLVVVFALIVKLAFDVWQENFA
>NZ_CP019304.1|WP_076798166.1|627976_629788_-|proline--tRNA-ligase
MVLRLSKLFLRTLREDPADAEVASHRLLVRAGYIRRAAPGIYTWLPLGLSVLRKVEQIIREEMAAIGAQEVHFPALLPKEPYEATNRWTEYGEGLFRLQDRKGGDYLLAPTHEEMFTLLVKDLYSSYKDLPLSIYQIQNKYRDEARPRAGLLRGREFIMKDSYSFDVDDAGLDAAYAAHREAYLKIFERLGLEVIPVTATAGAMGGSKSEEFLHPTEVGEDTFVRSAGGYAANVEAVTTVAPAEIDFTNAPAAVIRDTPNTPTIDTLVAASNELAPRSEADGGPWTAADTLKNVVLAVTLPTGERQIVVLGVPGDRGVDLKRVEANIGAYLPVAGEIAVEAAGEEDLARNPLIVRGYLGPGMSLDEPLLGLEGAAKLLYLVDPRVVSGTAWITGANMAGKHVYDLVAGRDFTWDGVIECTEVRAGDEAPDGSGPLEIARGIEMGHIFQLGRKYAEALELKVLDQNGKQVVVTMGSYGVGVTRAVAALAESNHDAKGLVWPRSVAPADVHVVAVGRGDEIFEAAEQLALELEGAGLEVIYDDRPKVSPGVKFGDAELVGVPTILAVGRGLADGVVEIKDRRSGEAENVAVDKAVDYVVNAVRSN
>NZ_CP019304.1|WP_076798167.1|630110_630998_-|GNAT-family-N-acetyltransferase
MLSRVAPWLASHKDGAAPDGAAVRVLGVADTRQLRDLAGTDPVANVFILAHLESTDSAAPTPGGASVLGVFDDDALVGACWAGANLVPIQLDPELAGPVAAVAHRSGRRYASIFGPAGTVLALHRHLEELGHVAHEVRPDQPLMTITGAPAVEPNWELGFGQYADFDAILPACAAMFEEEVGYSPYLGGRDFYSRRVAGLIRQGHSLVHLKDGEVVFKAELGAVTSEVTQVQGVWMNPSHRGLGLSAGYMAAVVLLAQKLAPVTSLYVNDYNSRARATYERVGFRQVGTFATVLF

Crispr_ID: NZ_CP019304_2

• CRISPR_ID: NZ_CP019304_2
• CRISPR_location: 3792776-3792938
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP019304_2

Consensus_repeat	Method
CCCGTGCGCGAAGCGTGCGGGGGAGGTTGCGAGCGGGGAGGCGACGACGACGCT	CRISPRCasFinder

spacers of NZ_CP019304_2

>2.1|3792830|55|NZ_CP019304|CRISPRCasFinder
AGGAGCCGAGGGCCCCACTGCGAAGCGAAGCGAGCCAAGAGAGCGGCCAGGGATT

CRISPR arrays and Neighbor proteins around NZ_CP019304_2

CRISPR arrays

The CRISPR arrays of NZ_CP019304_2

>merge|NZ_CP019304|2|3792776-3792938|CRISPRCasFinder
CCCGTGCGCGAAGCGTGCGGGGGAGGTTGCGAGCGGGGAGGCGACGACGACGCTAGGAGCCGAGGGCCCCACTGCGAAGCGAAGCGAGCCAAGAGAGCGGCCAGGGATTCCCGTGCGCGAAGCGTGCGGGGGAGGTTGCGAGCGGGGAGGCTACGACGACGCT

>NZ_CP019304|2|2|3792776-3792938|CRISPRCasFinder
CCCGTGCGCGAAGCGTGCGGGGGAGGTTGCGAGCGGGGAGGCGACGACGACGCT	AGGAGCCGAGGGCCCCACTGCGAAGCGAAGCGAGCCAAGAGAGCGGCCAGGGATT
CCCGTGCGCGAAGCGTGCGGGGGAGGTTGCGAGCGGGGAGGCTACGACGACGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019304.1|WP_083706348.1|3791694_3792708_-|selenide,-water-dikinase-SelD	unknown	unknown	gnl|CDD|273100
NZ_CP019304.1|WP_076801496.1|3794445_3796233_+|selenocysteine-specific-translation-elongation-factor	unknown	unknown	gnl|CDD|182508
NZ_CP019304.1|WP_076801501.1|3798544_3800086_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NZ_CP019304.1|WP_083706349.1|3801259_3801889_-|PH-domain-containing-protein	unknown	unknown	gnl|CDD|371225
NZ_CP019304.1|WP_076801473.1|3778106_3779390_-|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl|CDD|272979
NZ_CP019304.1|WP_076801505.1|3803961_3804813_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|379207
NZ_CP019304.1|WP_076801478.1|3780619_3781696_+|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	unknown	unknown	gnl|CDD|234893
NZ_CP019304.1|WP_076801494.1|3793099_3794443_+|L-seryl-tRNA(Sec)-selenium-transferase	unknown	unknown	gnl|CDD|235278
NZ_CP019304.1|WP_157365187.1|3786951_3789615_+|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|273689
NZ_CP019304.1|WP_076801499.1|3796588_3798367_+|ABC-transporter-family-substrate-binding-protein	unknown	unknown	gnl|CDD|173866
NZ_CP019304.1|WP_076801485.1|3786315_3786882_+|dehydrogenase	unknown	unknown	gnl|CDD|239153
NZ_CP019304.1|WP_076801490.1|3789615_3790611_+|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|319882
NZ_CP019304.1|WP_076801483.1|3784560_3786009_+|hypothetical-protein	unknown	unknown	gnl|CDD|379050
NZ_CP019304.1|WP_172804302.1|3783193_3784285_+|redox-regulated-ATPase-YchF	unknown	unknown	gnl|CDD|236583
NZ_CP019304.1|WP_076801508.1|3805085_3807014_+|translational-GTPase-TypA	unknown	unknown	gnl|CDD|224138
NZ_CP019304.1|WP_076801503.1|3801968_3803843_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NZ_CP019304.1|WP_076801475.1|3779711_3780560_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019304.1|WP_076801510.1|3807042_3807411_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019304.1|WP_076803789.1|3800112_3801216_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_CP019304.1|WP_076801492.1|3790607_3791690_+|polysulfide-reductase-NrfD	unknown	unknown	gnl|CDD|309148

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019304.1|WP_083706348.1|3791694_3792708_-|selenide,-water-dikinase-SelD	gnl|CDD|273100	TIGR00476, selenide_water_dikinase, selenium donor protein. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements: SelC is the tRNA itself, SelD acts as a donor of reduced selenium, SelA modifies a serine residue on SelC into selenocysteine, and SelB is a selenocysteine-specific translation elongation factor. 3-prime or 5-prime non-coding elements of mRNA have been found as probable structures for directing selenocysteine incorporation. This model describes SelD, known as selenophosphate synthetase, selenium donor protein, and selenide,water dikinase. SelD provides reduced selenium for the selenium transferase SelA. This protein itself contains selenocysteine in many species; any sequence scoring well but not aligning to the beginning of the model is likely to have a selenocysteine residue incorrectly interpreted as a stop codon upstream of the given sequence. The SelD protein also provides selenophosphate for the enzyme tRNA 2-selenouridine synthase, which catalyzes a tRNA base modification. It also contributes to selenium incorporation by selenium-dependent molybdenum hydroxylases (SDMH), in genomes with the marker TIGR03309. All genomes with SelD should make selenocysteine, selenouridine, SDMH, or some combination.	3.36197e-147
NZ_CP019304.1|WP_076801496.1|3794445_3796233_+|selenocysteine-specific-translation-elongation-factor	gnl|CDD|182508	PRK10512, PRK10512, selenocysteinyl-tRNA-specific translation factor; Provisional.	1.22045e-89
NZ_CP019304.1|WP_076801501.1|3798544_3800086_+|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.41087e-51
NZ_CP019304.1|WP_083706349.1|3801259_3801889_-|PH-domain-containing-protein	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	5.84618e-06
NZ_CP019304.1|WP_076801473.1|3778106_3779390_-|exodeoxyribonuclease-VII-large-subunit	gnl|CDD|272979	TIGR00237, exodeoxyribonuclease_VII_large_subunit, exodeoxyribonuclease VII, large subunit. This family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits. [DNA metabolism, Degradation of DNA].	1.10828e-143
NZ_CP019304.1|WP_076801505.1|3803961_3804813_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|379207	pfam13472, Lipase_GDSL_2, GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.	9.86159e-15
NZ_CP019304.1|WP_076801478.1|3780619_3781696_+|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	gnl|CDD|234893	PRK01045, ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed.	0
NZ_CP019304.1|WP_076801494.1|3793099_3794443_+|L-seryl-tRNA(Sec)-selenium-transferase	gnl|CDD|235278	PRK04311, PRK04311, selenocysteine synthase; Provisional.	0
NZ_CP019304.1|WP_157365187.1|3786951_3789615_+|molybdopterin-dependent-oxidoreductase	gnl|CDD|273689	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit. This model describes a subset of formate dehydrogenase alpha chains found mainly in proteobacteria but also in Aquifex. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits of 32 and 20 kDa. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase. In E. coli and Salmonella, there are two forms of the formate dehydrogenase, one induced by nitrate which is strictly anaerobic (fdn), and one incuced during the transition from aerobic to anaerobic growth (fdo). This subunit is one of only three proteins in E. coli which contain selenocysteine. This model is well-defined, with a large, unpopulated trusted/noise gap. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	0
NZ_CP019304.1|WP_076801499.1|3796588_3798367_+|ABC-transporter-family-substrate-binding-protein	gnl|CDD|173866	cd08501, PBP2_Lpqw, The substrate-binding domain of mycobacterial lipoprotein Lpqw contains type 2 periplasmic binding fold. LpqW is one of key players in synthesis and transport of the unique components of the mycobacterial cell wall which is a complex structure rich in two related lipoglycans, the phosphatidylinositol mannosides (PIMs) and lipoarabinomannans (LAMs). Lpqw is a highly conserved lipoprotein that transport intermediates from a pathway for mature PIMs production into a pathway for LAMs biosynthesis, thus controlling the relative abundance of these two essential components of cell wall. LpqW is thought to have been adapted by the cell-wall biosynthesis machinery of mycobacteria and other closely related pathogens, evolving to play an important role in PIMs/LAMs biosynthesis. Most of periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the LpqW protein. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	9.84634e-141
NZ_CP019304.1|WP_076801485.1|3786315_3786882_+|dehydrogenase	gnl|CDD|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	1.70814e-45
NZ_CP019304.1|WP_076801490.1|3789615_3790611_+|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|319882	cd10560, FDH-O_like, beta subunit of formate dehydrogenase O (FDH-O) and similar proteins. This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.	6.45088e-116
NZ_CP019304.1|WP_172804302.1|3783193_3784285_+|redox-regulated-ATPase-YchF	gnl|CDD|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NZ_CP019304.1|WP_076801508.1|3805085_3807014_+|translational-GTPase-TypA	gnl|CDD|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
NZ_CP019304.1|WP_076801503.1|3801968_3803843_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NZ_CP019304.1|WP_076801483.1|3784560_3786009_+|hypothetical-protein	gnl|CDD|379050	pfam13175, AAA_15, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	4.34502e-06
NZ_CP019304.1|WP_076803789.1|3800112_3801216_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	4.01219e-81
NZ_CP019304.1|WP_076801492.1|3790607_3791690_+|polysulfide-reductase-NrfD	gnl|CDD|309148	pfam03916, NrfD, Polysulphide reductase, NrfD. NrfD is an integral transmembrane protein with loops in both the periplasm and the cytoplasm. NrfD is thought to participate in the transfer of electrons, from the quinone pool into the terminal components of the Nrf pathway.	1.46017e-14

Protein sequences

>NZ_CP019304.1|WP_083706348.1|3791694_3792708_-|selenide,-water-dikinase-SelD
MDGIMALDQEQSGAVRLTGYAHGGGCACKIPPGELEDVVRGLAGQTHPDVLVGLDGGDDASAVLVSEDLAVLSTADFFTPVVDDAYDWGRIAAANALSDIYAMGGRPVSAINLVGWPRGVLPMELLAEVLRGGLAVAAEAGCPVTGGHSVDDPEPKYGMAVTGIADPGKLLRNDAARPGLPLTLTKPIGLGFLNNRHKQTGEVFDEAVATMVQLNREAAGAAVQRGLRAATDVTGFGLLGHLYKMCRASGVGAVIDQSAVPLVSGAREALRDGFVSGGTRRNLDWVRPHLRPGPGVSEENLLALADAQTSGGLLVVGELPGHPVVGYTTEGPGIEVR
>NZ_CP019304.1|WP_076801492.1|3790607_3791690_+|polysulfide-reductase-NrfD
MTVSDFDEYRPPEPPRGRKGHGKRRRAGTGGGRGEEPMVPEAEFTSYYGRPIVKPPPWGDPIAVYLFLGGVAGGSALLGVGGQVTGNQVLCRNSRLAALAAVGLGAVALVEDLGRPERFLNMLRTIKLTSPMSLGSWVLTAFSAGVGVSAVSEIDRMTGSRLPLGPLRRLLRGLEGPAGVEAAVFAAPLSVYTAVLLSDTANPTWNAAREDLPFVFVSSASLAAAGLAMITTPVKEAGPARALAVLGVAGDLIATRVMEKNMDPVAAEPLHLGGPGRMLAWSEGLAVAGGVGALLGGRHRLTAAVSGVALLGASALTRFGILRAGIRSTENPRYTVEPQKNRLAARRRAGVVHDSITTAE
>NZ_CP019304.1|WP_076801490.1|3789615_3790611_+|4Fe-4S-dicluster-domain-containing-protein
MNQLTESPDHVRHTGHPRKGFFTDTSICIGCKACEVACKEWNRNPSDSEYELLESSYDNTGSLGADTWRHVAFIEQDREQIGRARESGRALVSLGMPGFGPPGQHKASALAGADTTPPDTPDFRWLMSSDVCKHCTNAGCLDVCPTGALFRTEHGTVVVQDDVCNGCGTCVAGCPFGVIERRRNGTVGTKTERDFTPGEQAPTRNVGVAQKCTLCYDRIVDGQTPACAQTCPTTSIKYGERETMVATAKERVAELHAQGLTEARLYGANDSDGVGGTGSVFLLLDEPEVYGLPPDPRVPTADLPRMFKRAGIAAAGMLAAATAAFLVGGRA
>NZ_CP019304.1|WP_157365187.1|3786951_3789615_+|molybdopterin-dependent-oxidoreductase
MANADCIVIQGSNMAECHPVGYQWVTEAKARGAKVIHVDPRFTRTSAVADKHVPIRAGSDVVLLGALINYVISNELWFKEYVLAYTNAATLVGEDFRDTEDLDGLFSGFDPETGQYDLSSWAYERKEGAESGGGHEHGADTSARAAGHQYGSGGPTLENPRFEHDYTLEHPRSVFQILKRHYARYTPEMVREACGISPEDFDYLARAITENSGRDRTTCFAYAVGWTQHTLGAQFIRTAAILQLLLGNVGRPGGGVMALRGHASIQGSTDIPTLFNLLPGYLPMPKAAMETLEQYLEGISSPSQKGYWAAADTYTISLLKAWWGDAANEESEWGYQYLPRITGGHGTYETVMSMLDGDVEGYFLFGQNPAVGSAHGRMQRLGMSHLKWLVVRDLSLIESATWWKDGPEIASGELKTEDIATEVFFMPAATHVEKSGSFTQTQRMLQWRHQAVQPPGDCQSELEFFYELGKRIRAKLADSTDERDRPLLDLTWDYPVDEHGEPDGEAVLAEINGMHLTGPQAGKPLSSYTEMRADGSTSGGCWIYTGVYADGINHAADRKPAQEQGQVAPEWGWVWPANRRILYNRASADPDGKPWSERKKYIWWDPEQNRWTGEDVPDFPVERAPGSRPDVDAGGAEALAGDDAFIMQSDGKAWLFAPKGMVDGPLPTHYEPQESPIANPLYRQQQNPARLTFPRADNLSAPSAGERGSEVYPYVFTTYRLTEHHTAGGMSRWLPYLAELQPEMFCEVSPALAAERGLEPYGWATIISPRSAIEARVLVTDRVKPLIVSGRTFHQIGLPYHWGVGQDAVVSGDAANDLLGVTLDPNVQIQESKAGSCDIVPGRRPRGAALLSLIAEYQTRAGVTPETGNQKVTGPGRATGHGTKEEN
>NZ_CP019304.1|WP_076801485.1|3786315_3786882_+|dehydrogenase
MSRFSFLGWPVVRQFASGDPLGRGEAVTSPKTRGITPRTSTADRVVQSVCPYCAVGCGQRVFVKDEKVVQIEGDPDSPISRGRLCPKGSASEQLVNAPGRQTKVLYRAPHAKDWQQLDLETAIEMVADRFLEARRNKWQQNDDQGRPLRRTMGIAGLGGATLDNEENYLIKKLFTAAGAIQLENQARI
>NZ_CP019304.1|WP_076801483.1|3784560_3786009_+|hypothetical-protein
MPSIDSRARVWERIGVERGVVERLDVASSPVLAQGSVKFGRLTALTGVHGAGKSYLLSAVAEGLPGWQTKTNLPIETTGHEAEFSGDYALALRTGSPADLVNFSRPIHWRHRRDYDASLQPLVATRLTPFTALSDLSYFSQNWMPTRPSEPLEVADLKRSQVDALQAITGHTYESVAYGHFEENDQYFPYFRVMRSSHETEVWTMSASEFWVHYVIWHLRSADENEVVLIDEPETFLAQPGHRGFVDEIARLALETGCQVILATHSEVMIRRLPAEVVRQVSGTASGAVISEVAHTEALLRTLGRARAPLSLLVFVEDDMARKIVHFFLGCYAPDRAAQVDVIDSGGKDEVVRGVNIAGRSRQLRTVGVLDGDQRDRYADEKLLFLPGVMAPELLLLEVLRCRDHDAAAGLGATTPDLHIAIDAARFVPHQRVFEVMSEVLVSSTPDDLVRVALSMWLEDGSTAAAARRLVEQMLTLVAHDH
>NZ_CP019304.1|WP_172804302.1|3783193_3784285_+|redox-regulated-ATPase-YchF
MSVALTIGIVGLPNVGKSTLFNALTRNQVLAANYPFATIEPNVGVVNLPDPRLQQLAGIFGSQRVLPAAVSFVDIAGIVKGASEGEGLGNQFLANIREAEAIAEVVRVFDDPDVIHVDGKVDPRSDMETIHTELILADLQTIEKAIPRIEKEVKIKKREAAELAAIKAAQVVLERGDTIYSSIESDKLEMEHLKELSLLTAKPFIYVFNADEGILGSEEKQAELRAMVAPADCIFLDAKLEADLVELDEAEAREMLEMNGQDESGLDQLARVGFHTLGLQTYLTAGPKEARAWTIRQGDTAPQAAGVIHSDFQRGFIKAEIVSFEDLIDAGSMAEAKSRGKVRIEGKEYVMADGDVVEFRFNV
>NZ_CP019304.1|WP_076801478.1|3780619_3781696_+|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase
MTSSAVSLSMPTVPRRRRSPEEVLAAAPVPGPKKVLLAAPRGYCAGVDRAVIAVEKALQHYGPPVYVRKQIVHNVHVVSSLEEQGAIFVDETDEVPEGALVIFSAHGVSPAVVQSAEDRGLRTIDATCPLVTKVHKEAVRFAKDDFDILLIGHDGHEEVEGTSGEAPDHIQIINGPHEVDKVTVRDPEKVIWLSQTTLSVDETMETVRLLKERFPTLQDPPSDDICYATTNRQVAIKKIAPQADLVIVVGSANSSNSVRLVEVALEYGAKASYRVDFANEVDESWFEGVATVGVTSGASVPEVLVKDVLRLLADYGYDAVEEIVTAEEDLLFSLPKELRATLKEAGDVSRALGGRRSR
>NZ_CP019304.1|WP_076801475.1|3779711_3780560_+|hypothetical-protein
MRSFLAALAVILGLLLSAAAVPAIWVDRNIVQENGFVALAAPLGKDPDFQKRLATAAVNSIDAGGTVPPQVAGLVRPVLESAATSLTGLPEYPAAWEETLRKSHRLNFTDPASLPPEADSSTSLTLDVAPLVALAAKQVSRQVGVPLEAPGQTLVNIGQANQRQLVEQVTAYSPLGYSLAVGAGVAFLLALVAARRRWKVLAGIGVGALVVAGLWALVSRWAADLVIATASGNEMADLFKREFVAASAAGFASWTLATAIAGGVLVAAGVLIRVVGGPARRR
>NZ_CP019304.1|WP_076801473.1|3778106_3779390_-|exodeoxyribonuclease-VII-large-subunit
MAENATVPVPGTAPAPRASTVPATAADTSPDNPWPLQLLSQKLKTHIERAPAAWVEGQVIELNRRGGSAFLTLRDVDAEISLPASIWSKLLDRQETPLERGSRVVALLKAEFWLKTGRLNMSVKDIRPVGLGDLLARIERLRHALAAEGLFAESRKKRLPLLPHRIGLITGRDSDAKKDVLRNAALRWPAVEFEIREVAVQGNTAVSQMVKALRELDARPEVDVIVIARGGGALEDLLPFSSEELIRAVAAAVTPVVSAIGHEADRPILDDVADLRASTPTDAAKRIVPEVSEELARVRQAEAQLRRSVTLLVARETDRLAAIRSRPVLAAPESMITARAEDVERLARRSTAAIGAALTRASDQLVHLQAQVRALSPQQTLDRGYAVVQLPGSAGAVVRQPSQAPAGTALSVRVAGGRFGAESTGTP
>NZ_CP019304.1|WP_076801494.1|3793099_3794443_+|L-seryl-tRNA(Sec)-selenium-transferase
MGKVDPRRFIPRTDRLLAHPELQCARGRLGDDVIRSIVQEIQDLARSGGLAPEEVEAEVLAAVSSRQATSLRPVLNATGIIVHTNLGRAPLSGSARAALLAAAGYVDVEMDLPSGTRSKRGTGAREALLRACPAAEDALAVNNGAAALLLATTVLAGTGEVIISRGELIEIGAGFRLPELIESTGARLREVGATNRTHLRDYESAIGERTGCLLKVHPSNFRISGFTSGVGVSELRSLADEHQVPLVVDLGSGLLAPDPVLPEEPDIASALASGADVVIASGDKLLGGPQAGLLLGRAEVIARLARHPLARALRADKLALAALEATLSGEAPPVTAALHADPVRLRERTEALAEAVGGAVIEHDGRVGGGGAPGVPLPGWAVRLPENMARWLRTGTPAVLPRVHSGACLVDLRCIPEDDDERLAGAVKSALAHALAHAAEPLGTEGN
>NZ_CP019304.1|WP_076801496.1|3794445_3796233_+|selenocysteine-specific-translation-elongation-factor
MFVVATAGHVDHGKSTLVRALTGMEPDRWAEERRRGLTIDLGFAWTRLASGKDVAFVDVPGHERFLGNMLAGLGPAPAVCFVVAADEGWQAQSSDHRDAIAALGISHGIVVLTRSDRAPGGVDEVLARVRAELAGTGLRDAPAVTVSAVQGTGLGELRSALDDMLMSLPEPEPDARIRLWIDRSFTIGGAGTVVTGTLTAGTLAQGDRLLLLGHDAARPVSVRALHSRNQAADSIGPSSRVAVNLRSGLSADTIHRGDVLLTGDSWTVVDAIDVRRTTGAPFTDAPGQLLVHIGTAAVPARMRPFEADHARLTLDRRLPLELGDRLVLRATGSRSVLAGAQILDVEPPALKRRGDSSRRAGVLAAMSPGGDALTEVARRGAVRVEQLRRMGVSGLARVPDGVKAFGDWWVHEPVLDAWRRRLRSAVEQLGEQDPLAAGLSSGAARDLIGPAGGVLLEAVVREAGLEQRAGFIMLPGQRPGLGAAEAGIAALENRLKIAPFAAPEAHELNALGLGARELAAAERSGRLLRLGEGVVLLPRAPALAMRELAALPQPFTTSEARKALGTTRRVAIPLLEYLDSRGWTRRLDAARRTVA
>NZ_CP019304.1|WP_076801499.1|3796588_3798367_+|ABC-transporter-family-substrate-binding-protein
MRFSRISKAVGVAAAAALALSACASTNGGTTPSSNAAGKQGGTATVVEVNAFNTFNPNTADGNTDINSKVSYATHSGFYYIDNQLNIVHNDKFGKMEKTSDDPLTVKYTINEGVKWSDGTPVTAADLLLQWAAFSGYYNDADAEGKAGTSYFSYAGDPTGLALTDFPEIGDDNRSMTIKYSKPFADWEIALGGPGIDIPAHVLAKKAGLADTQAFIDHLKAMPRGDAKAPKAADAKLKAMSDMWNTGFDSKTLPSDPSLFLSNGPFVVQSINQDQSLTMVRNKDYNWGPEPKLDEITVRYIGSSPAQVQALKNGEADIIAPQASADTLEQLKALESQGVTVEQGNQLSYDHIDLNYSGPFAEKSVREAFMLTVPRKDIVDKIIKKLDPEAKPLDSQLFVPAQPAYETSVQENGSSKYQDADVDAAKKLLNGATPEVRIMYNKDNPNRVDAFSLIRESATKAGFKIVDGGLGASDWGKALGKGGYDATIFGWINPGVGVSGVPQIFRTGNGSNFNKFSDPEADKLMDELIVTTDRSKQDELTKQIDKKIWDSAYGLPLFQSVGVDAYSDRITGVKFMPNQTGVWWNFWEWAEK
>NZ_CP019304.1|WP_076801501.1|3798544_3800086_+|ABC-transporter-permease
MVTYIVRRLVTAALILLGASFLVYLLTAASGDPLAEFRASSAPNKQQLMDSRSALLDLDTPAPVRYFKWLGGAAQCLVPFAGSCDLGKNIAGQPITDALGHALIQTLTLVTGATILAILVGITLGIITALRQYSTLDYGVTFMAFLFFSLPIFWVAVLLKEFGAIGFNNFLRNPEIPLPVSLGTGAVLGAVAVVVAGGDARRRALTGGVVFAVVAAVLIYFSVTQWFKTPGLGPVVIAIAGVGIAFAVTLLTAGLRNRKALQSALIAVGAGVVLYFVIQPLLNQATFLMIVLLGIAAVLAGMAIGYFMGGYDRGQSMRAAAITSFLVGFLILLDRFMQAWPAYFNNSRVRGRPIATIGAGTPNIEGDFWILGIDSFTHLILPTTALILISLAGYTRFTRASMLEIMNMDYIRTARAKGLSERTVVMRHAFRNALIPVATIVAFDIGGLIGGAVITETVFSVRGMGFLFLDGIQHVDPNPVMGVFICVAITAMAFNLIADLAYSALDPRVRVKA
>NZ_CP019304.1|WP_076803789.1|3800112_3801216_+|ABC-transporter-permease
MAEQAGLRQEAAGVEPVTEARGMSQGQIVRKRFLGHSGAIVGLVVFAIIFVMAFTSVGYAGIPGWWKYTHEAVSPLANNGAPTASLWPLAWGEHPFGQDRIGRDLFAMTMRGAQQSITIMVVIGLIAGLIGVVVGALSGYFRGWMEAVLMRLTDVIIIVPALLLAAVMAQLAGRRDEGSWFAAFASSNGVLALGIFLGLISWVGLARLMRGEFLTLREREFVDAARISGASNARIIFKHILPNAVGVLIVNVTLTMSAAILTETALSYLGVGVKSPDTSLGLLISQNQEAFATRPWLFWFPGLFIVLICLSINFIGDGLRDAFDPRQKKFNAKKAKDSAAAVPEATPVAALDTTAEDRRAAGGDRGA
>NZ_CP019304.1|WP_083706349.1|3801259_3801889_-|PH-domain-containing-protein
MSTVPHAGNAVIFKARTNKWFAGFSWFVAAAGLAGLMVAGGPGALSGVWPLLLIAYLGWLLFWRPAVVVHDAGVTIENPFRAITVPWPALVQVDTRYALTLITPGRSYGAWAAPAPGIWGGRNARPEDLRGLPGSTYGPGNSVRPGDLKTTDSGQAAQLVRARWEQLVEAGLVDAGAAETTPVTVKFRWLEAAAALLLLGLSYWSMAVL
>NZ_CP019304.1|WP_076801503.1|3801968_3803843_+|ABC-transporter-ATP-binding-protein
MTDYISPDRPASDPLERDPIEPGGGQRKAAGKGAVVLEVRDLSVDFGVEKKWVPAAVGLNYEVRAGEVLAIVGESGSGKSASSMALLGLLPSNSRVSGSVRLSGKELLGADAANIRSVRGKDVAVIFQEPMTALNPVYTVGAQIVETVRLHNEVSPEQAKERALRMLELVELPDPEKAFKSYPHQLSGGQRQRAMIAQSLSCDPRLLIADEPTTALDVTVQAEILDLMRNLRNKLDSAIVLITHDMGVVADLADRIAVMRKGLIVETGTAEQIFHNPQHPYTQALLAAVPHLGQGGTEAEPDVDVTAALAAATHAELESVDHEELVRRERENAAALAAAESRGPVGEPVLELTDVAIEYPKQGRVPAFRAVEGANLTIHPGQVVGLVGESGSGKTTIGRAAVGLLPVAAGTMRVVGQDISAAKKNGKQLHHVRRHIGMVFQDPSSSLNPRLPIGESIGEPMYLAGVAKGADLQKRIEALLDQVELPRNYRNRYPHELSGGQKQRVGIARALSLKPKLMVADEPTSALDVSVQAKVLELFQNLQRELGFACLFVTHDLAVVDVLADRICVMQRGRIVEQGSRDQILRNPQEAYTQRLLAAVPLPDPEKQRERRELRAQLLATGTE
>NZ_CP019304.1|WP_076801505.1|3803961_3804813_-|SGNH/GDSL-hydrolase-family-protein
MFQASTRALLIGPVIAASVFLAGCGAAQEPASGAGTAAPAAAGAAAPVAAPGEAVAAGSAVVSDLGAAVDPATLPAGALYRNPVNGRDEVIVGNIATTALLIGDSQSEPQGSWPRRALAGLGYEVFFCGKGGTGFVASNGSTGNYVDALQRGHWHLPYGFPPLVLIEGGGNDAKQGASDEQISANADRLITTIKQRYPGAKLAMVGTLGKGAEHGGVRRAEVDALLGTVAADHGIPFVSVGDWLSRYGLEAQLKDSVHMNNDGHRALGVLLGDRLAKLGLALS
>NZ_CP019304.1|WP_076801508.1|3805085_3807014_+|translational-GTPase-TypA
MSETTTQTAANIASRSDLRNVAIVAHVDHGKTTLVDAMLKQTNSFASHGEVEDRVMDSGDLEREKGITILAKNTTVAYNGPSSNGETITINVIDTPGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVLRKALAAHLPVVLLVNKTDRPDARIEEVVHESMDLLLGLASDLADEVPDLDLDEILNVPVVYAAAKVGRASLEQPADGAAPENEDLEPLFKTIIEHIPAPTYNPEGVLQAHVTNLDASPFLGRLALLRVYNGTLRKGQQVAWARQNGELKTVKITELLATKALERVPAESAGPGEIVAVAGIEDITIGETLTDVENPQPLPLITVDDPAISMTIGINTSPLAGKVKGAKVTARQVKDRLDKELIGNVSIKVLPTERPDAWEVQGRGELALAILVEQMRREGFELTVGKPQVVTKTIDGKVHEPMEHMTIDVPEEYLGAVTQLMAARKGRMTNMANHGTGWVRMEFIVPARGLIGFRTKFLTDTRGAGIAASISEGYEPWAGPIEYRTNGSMVADRAGVVTPFAMINLQERGSFFVKPTSEVYEGMIVGENSRADDMDVNITKEKKLTNMRAASSDSFENLTPPRELTLEESLEFAREDECVEVTPDDIRIRKVILDSNERAKANRARAKA
>NZ_CP019304.1|WP_076801510.1|3807042_3807411_+|hypothetical-protein
MNRGAAGRAGGLAAALPAALFAALAGTALHRQELPATGAALPLGAVAALLLLASLQLFLGAAFRTLIPTAVCGAGCYVLAGWWSGMEPGKRLIAGHLAGMIWVYGIVAVTVVMLVWCRRYRR

Crispr_ID: NZ_CP019304_3

• CRISPR_ID: NZ_CP019304_3
• CRISPR_location: 4855752-4856528
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 14 spacers

Consensus repeat of NZ_CP019304_3

Consensus_repeat	Method
TGCCCCCTCCCNGCAGGCTGC	CRT

spacers of NZ_CP019304_3

>3.1|4855773|33|NZ_CP019304|CRT
GCGGTCCAAGCCGACGGAACCATGCCGGCTAAC
>3.2|4855827|33|NZ_CP019304|CRT
GGTGTCAAAGCCGGGGTTGCCATGTCTGCAAAC
>3.3|4855881|33|NZ_CP019304|CRT
GTCGTCCAAGCCGACGGGACTATGCCCGCCAAC
>3.4|4855935|33|NZ_CP019304|CRT
GTCGTCCAGGCCGACGGGACTATGCCCGCCAAT
>3.5|4855989|33|NZ_CP019304|CRT
GTCGTCCAGGCCGACGGGACTATGCCCGCCAAC
>3.6|4856043|33|NZ_CP019304|CRT
GTCGTCCAGGCCGACGGGACTATGCCCGCCAAC
>3.7|4856097|33|NZ_CP019304|CRT
GTAGTCCAGGCCGACGGGACTATGCCCGCCAAT
>3.8|4856151|33|NZ_CP019304|CRT
GTCGTCCAGGCCGACGGGACTATGCCCGCCAAT
>3.9|4856205|33|NZ_CP019304|CRT
ACCGCCCAGGCAGGGGTCGCCATGCCGAACGGA
>3.10|4856259|33|NZ_CP019304|CRT
GTCGTCCAGGCAGACGGGACCATGCCCGCCAAC
>3.11|4856313|33|NZ_CP019304|CRT
ACCGTCCAGGCAGGGGTCGCCATGCCGAACGGA
>3.12|4856367|33|NZ_CP019304|CRT
GTCATTCAAGCAGACGGCACCATGCCTCCCAAC
>3.13|4856421|33|NZ_CP019304|CRT
GCCTACCAGTCCAACCAGCCTGTCACGCCGAAC
>3.14|4856475|33|NZ_CP019304|CRT
GCCACTCAGGCGAACACGCCAGTCCCCGACGGA

CRISPR arrays and Neighbor proteins around NZ_CP019304_3

CRISPR arrays

The CRISPR arrays of NZ_CP019304_3

>merge|NZ_CP019304|3|4855752-4856528|CRT
TGCGCCCTCCCACCGGGCTGCGCGGTCCAAGCCGACGGAACCATGCCGGCTAACTGCCCGCTCCCGGCAGGCTGTGGTGTCAAAGCCGGGGTTGCCATGTCTGCAAACTGCCCTCTCCCGGCAGGATGTGTCGTCCAAGCCGACGGGACTATGCCCGCCAACTGCCCCCTTCCCGCGGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAATTGCCCCCTCCCGGCAGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAACTGCCCCCTCCCGGCAGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAACTGCCCCCTTCCCGCGGGCTGCGTAGTCCAGGCCGACGGGACTATGCCCGCCAATTGCCCCCTCCCGGCAGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAATTGCCCCCTCCCGGCAGGCTGCACCGCCCAGGCAGGGGTCGCCATGCCGAACGGATGCCCACTCCCGGCAGGCTGCGTCGTCCAGGCAGACGGGACCATGCCCGCCAACTGCCCCCTCCCGGCAGGCTGCACCGTCCAGGCAGGGGTCGCCATGCCGAACGGATGCCCACTCCCAGCAGGCTGCGTCATTCAAGCAGACGGCACCATGCCTCCCAACTGCCCCCTCCCCGCAGGCTGCGCCTACCAGTCCAACCAGCCTGTCACGCCGAACTGCCCCCTCCCGGCAGCCTGTGCCACTCAGGCGAACACGCCAGTCCCCGACGGATGCCCCCTTCCGGCCAATTGC

>NZ_CP019304|3|1|4855752-4856528|CRT
TGCGCCCTCCCACCGGGCTGC	GCGGTCCAAGCCGACGGAACCATGCCGGCTAAC
TGCCCGCTCCCGGCAGGCTGT	GGTGTCAAAGCCGGGGTTGCCATGTCTGCAAAC
TGCCCTCTCCCGGCAGGATGT	GTCGTCCAAGCCGACGGGACTATGCCCGCCAAC
TGCCCCCTTCCCGCGGGCTGC	GTCGTCCAGGCCGACGGGACTATGCCCGCCAAT
TGCCCCCTCCCGGCAGGCTGC	GTCGTCCAGGCCGACGGGACTATGCCCGCCAAC
TGCCCCCTCCCGGCAGGCTGC	GTCGTCCAGGCCGACGGGACTATGCCCGCCAAC
TGCCCCCTTCCCGCGGGCTGC	GTAGTCCAGGCCGACGGGACTATGCCCGCCAAT
TGCCCCCTCCCGGCAGGCTGC	GTCGTCCAGGCCGACGGGACTATGCCCGCCAAT
TGCCCCCTCCCGGCAGGCTGC	ACCGCCCAGGCAGGGGTCGCCATGCCGAACGGA
TGCCCACTCCCGGCAGGCTGC	GTCGTCCAGGCAGACGGGACCATGCCCGCCAAC
TGCCCCCTCCCGGCAGGCTGC	ACCGTCCAGGCAGGGGTCGCCATGCCGAACGGA
TGCCCACTCCCAGCAGGCTGC	GTCATTCAAGCAGACGGCACCATGCCTCCCAAC
TGCCCCCTCCCCGCAGGCTGC	GCCTACCAGTCCAACCAGCCTGTCACGCCGAAC
TGCCCCCTCCCGGCAGCCTGT	GCCACTCAGGCGAACACGCCAGTCCCCGACGGA
TGCCCCCTTCCGGCCAATTGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019304.1|WP_076803275.1|4844236_4846315_-|ATP-binding-protein	unknown	unknown	gnl|CDD|223540
NZ_CP019304.1|WP_172804371.1|4870031_4872707_+|DUF3376-domain-containing-protein	unknown	unknown	gnl|CDD|274676
NZ_CP019304.1|WP_076803280.1|4849315_4849858_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019304.1|WP_076803288.1|4862497_4865245_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|224557
NZ_CP019304.1|WP_076803279.1|4848957_4849275_+|PAAR-domain-containing-protein	unknown	unknown	gnl|CDD|269823
NZ_CP019304.1|WP_076803274.1|4843368_4844118_-|DUF4157-domain-containing-protein	unknown	unknown	gnl|CDD|379338
NZ_CP019304.1|WP_076803291.1|4867893_4868598_-|hypothetical-protein	unknown	unknown	gnl|CDD|198111
NZ_CP019304.1|WP_076803277.1|4847267_4847888_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP019304.1|WP_076803281.1|4850451_4851474_-|ATP-dependent-DNA-ligase	unknown	unknown	gnl|CDD|240135
NZ_CP019304.1|WP_076803278.1|4848145_4848958_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019304.1|WP_076803294.1|4872656_4874513_-|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl|CDD|224777
NZ_CP019304.1|WP_076803283.1|4853639_4854323_+|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|226101
NZ_CP019304.1|WP_076803287.1|4861448_4862480_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340832
NZ_CP019304.1|WP_076803286.1|4859235_4861365_+|amylo-alpha-1,6-glucosidase	unknown	unknown	gnl|CDD|225942
NZ_CP019304.1|WP_076803276.1|4846322_4846979_-|DUF4255-domain-containing-protein	unknown	unknown	gnl|CDD|379449
NZ_CP019304.1|WP_076803289.1|4865347_4867087_-|HNH-endonuclease	unknown	unknown	gnl|CDD|367155
NZ_CP019304.1|WP_076803290.1|4867242_4867884_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019304.1|WP_157365241.1|4851622_4853617_+|amylosucrase	unknown	unknown	gnl|CDD|200463
NZ_CP019304.1|WP_076803295.1|4874509_4875544_-|hypothetical-protein	unknown	unknown	gnl|CDD|239819
NZ_CP019304.1|WP_083706488.1|4856805_4858986_-|elongation-factor-G-like-protein-EF-G2	unknown	unknown	gnl|CDD|237186

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019304.1|WP_076803275.1|4844236_4846315_-|ATP-binding-protein	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	3.90455e-28
NZ_CP019304.1|WP_076803281.1|4850451_4851474_-|ATP-dependent-DNA-ligase	gnl|CDD|240135	cd04865, LigD_Pol_like_2, LigD_Pol_like_2: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD, subgroup 2. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for non-homologous end joining (NHEJ)-mediated repair of DNA double-strand breaks (DSB). NHEJ-mediated DNA DSB repair is error-prone. It has been suggested that LigD Pol contributes to NHEJ-mediated DNA DSB repair in vivo, by filling in short 5'-overhangs with ribonucleotides; the filled in termini would then be sealed by the associated LigD ligase domain, resulting in short stretches of RNA incorporated into the genomic DNA. The Pol domains of PaeLigD and Mycobacterium tuberculosis (Mt)LigD are stimulated by manganese, are error-prone, and prefer adding rNTPs to dNTPs in vitro; however PaeLigD and MtLigD belong to other subgroups, proteins in this subgroup await functional characterization.	5.55016e-102
NZ_CP019304.1|WP_076803288.1|4862497_4865245_-|DEAD/DEAH-box-helicase	gnl|CDD|224557	COG1643, HrpA, HrpA-like helicases [DNA replication, recombination, and repair].	0
NZ_CP019304.1|WP_076803279.1|4848957_4849275_+|PAAR-domain-containing-protein	gnl|CDD|269823	cd14738, PAAR_2, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	4.98667e-18
NZ_CP019304.1|WP_076803274.1|4843368_4844118_-|DUF4157-domain-containing-protein	gnl|CDD|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	1.26801e-30
NZ_CP019304.1|WP_076803291.1|4867893_4868598_-|hypothetical-protein	gnl|CDD|198111	smart01043, BTAD, Bacterial transcriptional activator domain. Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.	9.80453e-15
NZ_CP019304.1|WP_076803276.1|4846322_4846979_-|DUF4255-domain-containing-protein	gnl|CDD|379449	pfam14065, DUF4255, Protein of unknown function (DUF4255). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 320 amino acids in length.	2.6794e-45
NZ_CP019304.1|WP_076803286.1|4859235_4861365_+|amylo-alpha-1,6-glucosidase	gnl|CDD|225942	COG3408, GDB1, Glycogen debranching enzyme [Carbohydrate transport and metabolism].	7.80115e-83
NZ_CP019304.1|WP_076803294.1|4872656_4874513_-|DNA/RNA-non-specific-endonuclease	gnl|CDD|224777	COG1864, NUC1, DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism].	1.47955e-45
NZ_CP019304.1|WP_076803283.1|4853639_4854323_+|dienelactone-hydrolase-family-protein	gnl|CDD|226101	COG3571, COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only].	8.34627e-41
NZ_CP019304.1|WP_076803295.1|4874509_4875544_-|hypothetical-protein	gnl|CDD|239819	cd04327, ZnMc_MMP_like_3, Zinc-dependent metalloprotease; MMP_like sub-family 3. A group of bacterial and fungal metalloproteinase domains similar to matrix metalloproteinases and astacin.	5.23962e-31
NZ_CP019304.1|WP_172804371.1|4870031_4872707_+|DUF3376-domain-containing-protein	gnl|CDD|274676	TIGR03607, TIGR03607, patatin-related protein. This bacterial protein family contains an N-terminal patatin domain, where patatins are plant storage proteins capable of phospholipase activity (see pfam01734). Regions of strong sequence conservation are separated by regions of significant sequence and length variability. Members of the family are distributed sporadically among bacteria. The function is unknown. [Unknown function, General].	1.07672e-17
NZ_CP019304.1|WP_076803287.1|4861448_4862480_+|glycosyltransferase-family-4-protein	gnl|CDD|340832	cd03802, GT4_AviGT4-like, UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.	6.8687e-98
NZ_CP019304.1|WP_076803289.1|4865347_4867087_-|HNH-endonuclease	gnl|CDD|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	3.32931e-18
NZ_CP019304.1|WP_157365241.1|4851622_4853617_+|amylosucrase	gnl|CDD|200463	cd11324, AmyAc_Amylosucrase, Alpha amylase catalytic domain found in Amylosucrase. Amylosucrase is a glucosyltransferase that catalyzes the transfer of a D-glucopyranosyl moiety from sucrose onto an acceptor molecule. When the acceptor is another saccharide, only alpha-1,4 linkages are produced. Unlike most amylopolysaccharide synthases, it does not require any alpha-D-glucosyl nucleoside diphosphate substrate. In the presence of glycogen it catalyzes the transfer of a D-glucose moiety onto a glycogen branch, but in its absence, it hydrolyzes sucrose and synthesizes polymers, smaller maltosaccharides, and sucrose isoforms. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP019304.1|WP_076803277.1|4847267_4847888_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.53069e-25
NZ_CP019304.1|WP_083706488.1|4856805_4858986_-|elongation-factor-G-like-protein-EF-G2	gnl|CDD|237186	PRK12740, PRK12740, elongation factor G-like protein EF-G2.	0

Protein sequences

>NZ_CP019304.1|WP_076803283.1|4853639_4854323_+|dienelactone-hydrolase-family-protein
MPTADTPVTIAVGDGHVSGAYARPANPFATLVLAHGAGAGMEHPFMRGFTGALNDDGVATLRFNFPYREAGRKFPDRPPAAIATWRAAMADAAARSAGKSEPVWAAGKSFGGRMASMAVAEGMPAAGLVYLGYPLHPPGKPEKLRDEHLYGLTTPMLFLQGTRDTFATRELLEGVVSRIGPTATLQWCEGGDHSFAVAGNKRSAEEIGASLAAPVAAYIRANNPAGH
>NZ_CP019304.1|WP_157365241.1|4851622_4853617_+|amylosucrase
MKATGAARRRASSKETHSMVESASLDATQGPSDAREPGEQQLFRTTAAEAGLVPGSRDWNALEERYDRHFPDLSRLFRSLYGSRPDVEEQLAALVAEMARSWQDRPADLKQLDDGREDNSDWFQSNRMLGGVCYVDRYAADLEGVRARIPYFKELGLTYLHLMPLFLAPEPLSDGGYAVSSYRKVNPKLGTMDQLRALAAELRANGISLVVDFIFNHTSNEHEWAQRAAAGEPRYSDYYWIFPDRTMPDAFEQNVREIFPEDHPGSFVQLPDGRWVWATFHTFQWDLNYSNPEVFRAMAGEMLFLANLGVDILRMDAVAFIWKQLGTPCESLPEAHTLLQAFNAVCRLAAPSLLFKSEAIVHPDEVALYIDPAECQLSYNPLQMALTWEALATRNVSLLAQALERRHNIAPGTSWVNYVRSHDDIGWTFADEDAAEFGINGFDHRRFLNSFYVNRFPGSFAHGVPFQDNPRTGDCRISGTTGSLCGLEEGSAEAIRRVLLTHSVAFSTGGIPLLYLGDEVGQLNDYGYAQEDGHEADSRWVHRPQFPAEKYAKRLDPATPEGAVYAGLRRLIEVRAATPELGGTRLVPFTTNNHAVLGYQRPGVGTAVLALANFSDGPQVVSAETLSGFAAEALDLFSDVPVRIDEGLVLRPQDYAWLRVVPAD
>NZ_CP019304.1|WP_076803281.1|4850451_4851474_-|ATP-dependent-DNA-ligase
MASEQTTLSVDGPNGPREMRISSPSRVLWPELGLTKLDLARYFVDVGEAFIRANGDRPVALQRFSGDVDGEMFFSKNPPKGAPDFIRTVKVVFPSARSHPMLVFDEPAAVVWAAQMNTVVFHPWPSHAVNSDNPDQLRIDLDPQPGTDYDDAIPAALELRKVLAEAGLDAFLKTSGNRGLHVYAPIEPTREFLDVRHAVIAAARELERRMPDRVTTNWWKEERGERIFVDFNQANRDRTIAGAYSPRALPHASVSCPITWDELADVRPKDFTILTVPDRLKTIGDPWADMHAKPGTIDTLLEWWERDIGNGLGELPFPPDYPKMPGEPPRVQPSRAKKPE
>NZ_CP019304.1|WP_076803280.1|4849315_4849858_-|hypothetical-protein
MKPDFIVVPPEACTVARGDPPDTPACLFVTVDLRNQGQGVHAVELGIESKSLAAKVGLSEKKTLEAGEEPKLTEVRVNIQPDDLGQTHEVTFMADPLKTIEEADEDNNLITVKITLPTADTLPATAVCPPETMDSTDGPSSPAAEGGQLPEGGQLPEGGGSDGSSSPAGSTETVPAAEGQ
>NZ_CP019304.1|WP_076803279.1|4848957_4849275_+|PAAR-domain-containing-protein
MPTGPALRVGDTALCSLSDGPKPHVGGPVTPAAGVPTVLIGGMPAAVANALPGGIVCVSPAPNGIAAGSLTVLIGGFPAARVGDLSLHGTPVGPGPGCPTVIIGG
>NZ_CP019304.1|WP_076803278.1|4848145_4848958_+|hypothetical-protein
MTTTASFDTPRLSIEGGAEGTTGITFRNDSEVVEEYSLRVVGPAESWAEVAPARVSLYPGHDTTADVTFRPPRSASVHAGEYLFGVQVLPTEHPEDAALPEGVVEVRPFLETTGELMPRMSQGKRGAKHNVALDNWGNVPITVELAGSDPGDLLEFELQPPELTIGPGEVQFTAVHVRPAEKIWSGTPTTRVFVVTATPEDGVPVLLDGSHVQYPILPWRTIKTVFCLLLLAAALTVAWHFSVESVRVSEPTSTNTSQGVAPNGVPNGTQ
>NZ_CP019304.1|WP_076803277.1|4847267_4847888_-|response-regulator-transcription-factor
MEPITVKVHARDPISEAGVASELRARPEVRVVRAPNAEARVVVVVADSVDEDALTLLRIVQRKGAARAVLVAGRLDDGDLVKAVETGVVGIVRRSEATPDRLISVILAAAAGEGSVPPDLLGRLLDQVGKLQRHVLGPRGIMFTGLAPREVEVLRLLADGLDTCEIARKLAYSERTVKNVVHDVTTKLQLRNRSHAVAYALREGLI
>NZ_CP019304.1|WP_076803276.1|4846322_4846979_-|DUF4255-domain-containing-protein
MIAQVDEALRTLIRTDALNGSEVDVVFDAPTKDWAARRNAPTVNLYLYDIREDVRRRERGLSEQRGDDGHVRTRRPAPRHYKLSYLVTAWTQRPEDEHRLLDQLLRCFLKYEALPDELVVGQLAETGLVVPLTVGLPPPEDRAFADVWSALGGELKPSLDIVVIAPVDTGIVYQAGPPASQGTHLDMSDLLDGGADVGRHQHVAPPAPARDNGKRQAR
>NZ_CP019304.1|WP_076803275.1|4844236_4846315_-|ATP-binding-protein
MGQNPSLAHLLGRISVVEERIRLLVAMRRAEDPQPDDPFRGLYLSDEAVDRLLEGEQPALRNSNGGLGAASARYRECEELAETAQAAGHPLRLRNLADKFGLSGLDVDLLLVALAADLDPRFEQFFGYLNDDVTRRRPSVAVALALCGEPLYAAGARARLLSGPLIWGGLLAVEDPDRPLPGRALRVPDRVVGHLLGDDAPDPALAAVLASPPEVTWGDPGPLARALDAGIRLAYLREPATGSGRILAAEALSSSGYPAIHLDLGRLANEREPLALVDAAVREARLRGAGLVAAPLAAISDHPQVLEVLHAEPQPVLFVGDAVWDPAWTSRPPLLVDVAASSSNERLELWRAALGSHDGLDVEAATSAFRLRPEQVVRAAGSALVQAALAEDGRATAAQLRAGARGENGSALDRLARRIEPAVGWGDLVLPDAVLQALQEVALRARHRERVLGDWSMRPGAGRGHGVAALFAGDSGTGKTMSAEVVAGELGLDLYVVDLATVVDKYVGETEKNLERIFAAAAGVNGVLLFDEADAVFGRRSEVKDAHDRYANIESAYLLQRMETFDGLAILATNLRANIDEAFTRRLDVLVDFPLPDAAHRTVLWDRCLRTLDRSADLDLAFLGKAFELAGGSIRSSAITAAYLAADDGGTVTMRHLVTAVQREYRKLGRLMLESEFGPYWGMLSTAKNSMG
>NZ_CP019304.1|WP_076803274.1|4843368_4844118_-|DUF4157-domain-containing-protein
MHSHDYDQPDADSLRAKSPRAEAPDPALLYKAAAAGRTDVVGSRGILALQRAVGNSGVRGVAEEERSPVLDVVSSGGGQPLEEPVRADMEGRLGHSFSDVRVHTGDAAHDSAASVNAHAYTVGSNIVFQRDKYDPGSDTGRTMLAHELTHVVQQRSGPVDGTATGTGVRVSDPSDRFEREAAATAERAMSAPAAPAAQRVEGGSAVVQRQAEDAAVQREDEDEEKETAQGSFMAGAAVQRDEAEEEESG
>NZ_CP019304.1|WP_083706488.1|4856805_4858986_-|elongation-factor-G-like-protein-EF-G2
MSVKGTNGRGKGPGRGSSDLRRADASAGAPVDKPEGIRNVALVGHSGAGKTMLLEALLAAAGTIPRMGSIVDGNTVSDAEPSEIHQQRSVVLSVAPLVYDGVKVNLLDTPGYGDFTGELRAGLRAADAALFVVSAVDGVDAATTALWAECAQLDTPRAVVITRLDHPRANFEAALAACQRAFGQSVVPAYLPVRTDGSVTGLLGLLSGQVSEYDGESPEPAVRDASADERAAAESERGTLIEGIISESEDESLMDRYLGGEDIDADVLVGDLEKAVARGSFFPVLAASAETGLGMTELLEMLTRAFPTPLERAVPDVTDLAGEPAGPLTCDPDGPLAGEVVRTTIDPFLGRVCLVRVFSGTLREDSAVHVSGRGLAERGHEDHDSDERLAHLYSPLGANLRPIPYCVAGDICAITKIGSAETGDTVSAKDAPLLITAWDMPEPLMPLAVEAATRSDEDALAKSLGKVAAGDPTLRVERNSETHQLILWCMGEAHGEVVLDRLRDQGVKLQTVPVVTPLRETFAAPAAGHGRYVKQSGGHGQYAICDIEVEALERGAGFEFVDKTVGGVVPNQFIGSVEKGVRAQMQKGVSAGFPVVDIRVTLVGGKAHSVDSSDAAFQSAGALALREAAAAGRIQLLEPVSSVTISIPDEYVGSVMSDLSARRGRLTGTTSSGGDVTEVTAEVPDGELLRYAVQLRALTAGTGRFRRSYLRHEPVPGNVAPAAANA
>NZ_CP019304.1|WP_076803286.1|4859235_4861365_+|amylo-alpha-1,6-glucosidase
MSAWNENIGAGSAGLTAVTVVEGSSFCISAESGDVFPGQPQGAFYQDTRILSRWQLTVDGVPLEPLSGQTREPYRAVFIGRPRGASGAVESPLVVEHNRTVGPGLRDDIKVHNYSEKPLTCRIQIRVDADLSDLFDVKGGKVVPSAEHSRKVRAEALQIDAIRNGIHRGVVISAQGAMVTEDALTFDADLAARGTWTASVFTTPLVDGAFPEQPFTHETAPHVGAQRYAAWEEHVPRLTVTDKNVEKVLTRSQEDLGALRIFDPEHPERAAVAAGAPWFMALFGRDSILSSYMALAVDPKLATGTLQTLAALQGKKVDPDTEEEPGRILHEVRLGVTAGLALGGSQAYYGTADATPLFVALLAELGRWGLAGDLLDSLLPHADRALDWIENYGDRDGDGFVEYQRANEHGLLNQGWKDSWDGINFADGSMAEAPIALCEVQGYVYGAYLGRALLAQQLGDTDMASKWNRKAADIKAEFNDRFWLPKKGYFAVALDKDKRPVDACASNMGHCLWSAIVDADKAPLVAERLMSPEMFTGWGIRTLASDMGAYNPVSYHNGSVWPHDTALIAGGLMRYGFVEEATRIAMGLFDAAEKFDGRLPELFCGFSRDDFPDPVPFPTSCSPQAWASAAPVHLMRILLRFDPLLPREEVCLAPVLPAAFGSFRADHVQMDSARITVQATGTEGSIDGLRQGLTLLHEPRPPLARLMRH
>NZ_CP019304.1|WP_076803287.1|4861448_4862480_+|glycosyltransferase-family-4-protein
MRIVLIAGPWYPIPPTGYGGIELVVDALARGFSRAGHEVLLACAADSTCPVPQLPGMRPSEPDFVGFTSSELSHVVNAYAGMDGMVDLVHDHTLAGPLYRGRPEGLPVVTTLHSDLNPSFTAVYGAAARDTTLIAISRSQVSSALADRVAAIIPHGMELSAVPVGQGQGGYACFLGRMCPDKGVVEAIEVARLAGIPLRIAAKMREPAEVQYFHDVVEPMLRPDVEFLGEVGGADKYKLLGEAVALLNPIQWMEPFGLVMIEAMATGTPVVATPIGSAPEVIDDGVTGYLASAPEELARLLLRAPDLDRATVRAQAEDRFSTERMVEDHLALYTRLIGVTSAR
>NZ_CP019304.1|WP_076803288.1|4862497_4865245_-|DEAD/DEAH-box-helicase
MTSALPLASSAPFNLDSIGSGLVFAESLGELAGVLQKQGAGGAAVVQAPPGTGKTTLVPPLVANLAQGSTAEGQPRIVVTQPRRVAARSAARRLAALDGTKLGDRVGYTVRGERQAGPATLIEFVTPGILLRRLLADPGLEGTAAVILDEVHERGLETDLLVGLLAEVRQLRGDLMVVAMSATLDAPRFAALLGGNEEGNEDGNMGGEHGGEADGGGPAPVVDCPSALHPLETAWAPAPAARLDGRGVTRAFLDHVADTAAASHAEALAADPGTDALVFLPGVWEVSHVAGQLRTRVGPGVEILELHGQASPAAQDRAVSGRQPGEPSRIIVSTALAESSLTVPGVRLVVDSGLSREPRRDAGRGMTGLVTVSCSRASAEQRAGRAARQGPGKVVRCYDQKTLGAAPAHQTPEIAVSDLTGAALILACWGAPGGRGLALPDTPPPLAMADATEVLRELGAVGDDGHAMELGKALARIPADPRLGRALLVGSALLEERQAGSGSASPAHAGFGTAAEVVAAVAGDQRANGADLPRLVSTLRSGKDPAARRWAEEARRLDTLARQAATGVGLPLVEVPSVELPAGSAEQVGMVVALAFPGRVARRVPGDGPERYLLTSGTRAGLPAGSPLAGHEWLAVAEVARADGRDAAGTGAVIRSAAPLTADAAEAAAAHLLRDSVEAAFSQGKVTARRERRLGAIVLSSTPVPASAADGHAAVARAVEEQGLGVIGWSTSADGLRRRLALLHRELGDPWPDMSEQALLARLDDWLGPELEALAGGVSTSGIDLADPIRRLLPWPDAARLGELAPEFLEVPSGSRVRIDYPQAEDDGGRPVVAVKLQECFGWDRTPRLADGKVAVQFHLLSPARRPLAVTDDLASFWSGPYAQVRAEMRGRYPKHPWPEDPWTATATARTNARK
>NZ_CP019304.1|WP_076803289.1|4865347_4867087_-|HNH-endonuclease
MDNSVAAAEVLEALGASALALAAELRGAADPGAAGGDFQPDPVDPLGEQATACLDGLRVVGGMEARLAAVKVELAAGYVTADAAMAVPVGSPQDAAVRQMAVRAEVAGALTISEGAAERLLVESDMLTRERPMTLAALQLGRISWQHARIMCDETEGLSPEAAAAFEAHFLDPDAPNAARGCFAGELAPGRFRAKARYWRERHHPDSIETRHSRSVKDRRLEYSPDRDGMAWISAFLPADQAAGIWNRTTAIARGLQGPTEIRTLTQLRADVFSTSLLRPAPGITGGAAGAGQGGSFPGGSAPAGEMTAGEVPSPQAQVLVTVPVFSLLGHTDEPATLDGYGPIPASMARRLVANGATSFFRVLTDPRDGAPLEIGRTSYRLTKPMRQWLRLRDAKCTFPNCTNHSLDNDADHILAWADGGGTGVTNLGQPCPKHHRLKHATAWRPVGATLESPPGWISPSGRHYPAEHQDWEPPTWPDNFAPGNFAPDNFAPDNFQPGWSDASPSQDCPELPPGRALPEPPDWFGAPSGHAEPEPSDWPDPPDQPHDPQDFDEIDERDDPEPPLPLDPWPNWSSVTAA
>NZ_CP019304.1|WP_076803290.1|4867242_4867884_+|hypothetical-protein
MLRLPRITVEVPVLGVGDRPADYEQLAAYADGLRKPEGLHMTLLHIGILDDFAADVVAWTKGATDPAAAAVKTADWLRALPVLEGFTGTAERLVLFGGGRVSGLDVEVPQHVRDFQVSLVAALRELLEDLLVDNPDDFILSSPALGYRYPRWHPHVAIGKPKSRDHSGEGRSGEGRSRERSGSWEIRPLKVEFGPSQIRNRQLLPGPGDGGHQ
>NZ_CP019304.1|WP_076803291.1|4867893_4868598_-|hypothetical-protein
MSGDDAGGFQLSLFQSWQLRQGGEALHVPLRQQRLITALALKGPRSRSYLVGLLWPAHSEPKALDSLRVSVHLIARQVPGLLANGGAVLSLNDTVEVDLHRLHQEILQPGLGCGDGHAAAFLSDLRRADLLPGWYEDWVMAEQAEFRRARLHALVGLAGELFGRAEYRLALEASEAALDLEPLYEQAVRVVVEVEQLQGNRVAALRAFENYKARLMAEMGLVPSEALQKMVAEG
>NZ_CP019304.1|WP_172804371.1|4870031_4872707_+|DUF3376-domain-containing-protein
MRHAFGSHRSSSDLPGEAVFHVVDGGVFDNIPIGRALTAARGRVSQRPAHRALLYLDPDSVGDSLPTSRSENLSRFLNAVGASALRLKRRESLDSEVKEYVDYVNALSLNLGRSEALAAVLSDRWSTEIAVDRRRAYVRYRASADVDLLTQVLTRPDEWQVASTVTDRRNFRALGSDELSGLDSRIIQKYRDISRQDEEGTAFRLLTSDAQALLDAAQCSFSWLRRMESESFPKELTDSIASFDALRTGIYGVINSAVILRDQAIWAVLEKSTDCAESVRHENIMAAWLSAAETNQPSRMQCWAALQSHFEVLVRYSADLTDRAADAGSHPELREWTESPWPDLTRIALLSAPDCGFTIHDLAPCLAAAGIPPVVARIRYWRIGSDERPAHACDYSLLKDGERRGAVAFALKNPSLSPCDLKDLLNPDAASLSSRFKLAGNTMANFSGFLSRDWRENDWWWGRLDAAAGISRFLETVAVDQNPRIPELDGDQELFDESTAEAPRGSRNRVTWLQDQLTDQWFGLQAAAPEDRRKARQSIRAGADSPSDLGAAYRMMLMSRGLRVLWRARPDGNLPTALGSWLLHVLLVPLFAVLPAIVHPARLAFILGFGDASLWVLARPENAVFGAQPFLLYLGLVLPGLIFLALAFVALADGHRRWRPVLEVLSGDRLLATEYRSHQRSAARKAMAGPVAVILLLVPLGLAASQARQLMVVVCLVFMGILTVATRKWAMSVPAPVHGKHPALDWGLACTGLLLAVAVPLVTELLHWSAARNWQSLAVLACSLLVLALVLTCDWLTAVGTLLTGLAASAGGILAAWGVWVLLATLRQSERTILCLFAAFVAWGLAVWWMPEITRMLRHRSDAVVTVPRRKGAEVSPPDVPGPVQRVPGLQ
>NZ_CP019304.1|WP_076803294.1|4872656_4874513_-|DNA/RNA-non-specific-endonuclease
MTGQESASRKSGAEEETRKSLRQFIRTRGAEYLKDPNISSIGVGYKMSEGSPTGELALQFTVDRKAAPDELEALGTVPIPGEIIIDGVAVPTDVIERSYRPGFRIVAEAEPPAAKVRVDPVLPGVSVAHYQGTAGTIGCIVYDKTDGEPLVLSNWHVLHGTCGALGDVVVQPGPYDDNRVDRNRLGVLKRSHLGVAGDCAVATIEGRTVNPEILGVGATPRELGEPEIGDKVLKSGRTTGLTHGVVRRVDVIAKLHYGAAGEQAIGGFEIGLDEQNLPEDGEISRGGDSGAAWLFKNADGTPGNVLAGLHFAGETGTSVDEHALACLPQSVFEKLGITLVRPDSGAIADAVAVGYDPSFLGVRLDPPTLDASLQGDAVPLDGSDIIPYTHFSLVMSAGRRFARWVGWNIDGGALKRIPRKSLSFTKDPRIPGRFQCGDELYSDNRLDRGHLARRADLLWGDLTEAEQANKDSFFFTNITPQLEDFNQSARKGVWGRIEDAVFADVDVQDLRVSVFGGPVFQANDRIYRGVPLPREYWKIVAFVEDGQLQGRAFLLTQNLNQLEALELDEFRVFQVAVREIQERTRLVFPENLRNADTFTAPESLQARDPLDRPGDIRW
>NZ_CP019304.1|WP_076803295.1|4874509_4875544_-|hypothetical-protein
MELESLPDEVLASIADRNAWRSQMAGSDTALEFLVSDLARWQPGSAVRVAFLDGDTALHADVAGATRQISDACNLELDFGVDAAGNYRRWHENDTFHAAEIRVGFNMGGYFSLVGTDSTDSTIGPPAGPVGGRPNQRSLNLGGFTTERPERWEGTVRHEFLHALAFHHSHQNMRGSCEAEFRWDDDQDYAPTTNAKGVFIPDAAGRRPGIYTYLAGPPNNWPRAKVDHNLRTVEDPAVVAGPFDSDSVMLYSFPDFFYKSSPSSCAPTGNGKDLSAGDRRGLALLYPHAAERLGDLQERAEAALAAMDGTGSSPETVEAAGGEYRDRALELLHALSGKGEGVGR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP019304_3	3.11|4856313|33|NZ_CP019304|CRT	4856313-4856345	33	NZ_CP039693	Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence	123895-123927	6	0.818
NZ_CP019304_3	3.11|4856313|33|NZ_CP019304|CRT	4856313-4856345	33	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	1985958-1985990	6	0.818
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MH976511	Gordonia phage Gaea, complete genome	17015-17047	7	0.788
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MT723937	Gordonia phage JKSyngboy, complete genome	17773-17805	7	0.788
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MH450129	Gordonia phage Ribeye, complete genome	18335-18367	7	0.788
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MT723941	Gordonia phage YorkOnyx, complete genome	17398-17430	7	0.788
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MH976509	Gordonia phage Bizzy, complete genome	17308-17340	7	0.788
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MH651168	Gordonia phage Ashertheman, complete genome	17407-17439	7	0.788
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MH976513	Gordonia phage Kroos, complete genome	17872-17904	7	0.788
NZ_CP019304_3	3.5|4855989|33|NZ_CP019304|CRT	4855989-4856021	33	MK967396	Gordonia phage Tangerine, complete genome	17000-17032	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MH976511	Gordonia phage Gaea, complete genome	17015-17047	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MT723937	Gordonia phage JKSyngboy, complete genome	17773-17805	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MH450129	Gordonia phage Ribeye, complete genome	18335-18367	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MT723941	Gordonia phage YorkOnyx, complete genome	17398-17430	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MH976509	Gordonia phage Bizzy, complete genome	17308-17340	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MH651168	Gordonia phage Ashertheman, complete genome	17407-17439	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MH976513	Gordonia phage Kroos, complete genome	17872-17904	7	0.788
NZ_CP019304_3	3.6|4856043|33|NZ_CP019304|CRT	4856043-4856075	33	MK967396	Gordonia phage Tangerine, complete genome	17000-17032	7	0.788
NZ_CP019304_3	3.9|4856205|33|NZ_CP019304|CRT	4856205-4856237	33	NZ_CP010683	Phaeobacter piscinae strain P14 plasmid pP14_b, complete sequence	3834-3866	7	0.788
NZ_CP019304_3	3.9|4856205|33|NZ_CP019304|CRT	4856205-4856237	33	NZ_CP010718	Phaeobacter piscinae strain P18 plasmid pP18_c, complete sequence	3834-3866	7	0.788
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MH976511	Gordonia phage Gaea, complete genome	17015-17047	8	0.758
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MT723937	Gordonia phage JKSyngboy, complete genome	17773-17805	8	0.758
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MT723941	Gordonia phage YorkOnyx, complete genome	17398-17430	8	0.758
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MH976511	Gordonia phage Gaea, complete genome	17015-17047	8	0.758
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MT723937	Gordonia phage JKSyngboy, complete genome	17773-17805	8	0.758
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MT723941	Gordonia phage YorkOnyx, complete genome	17398-17430	8	0.758
NZ_CP019304_3	3.9|4856205|33|NZ_CP019304|CRT	4856205-4856237	33	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	679884-679916	8	0.758
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MH450129	Gordonia phage Ribeye, complete genome	18335-18367	10	0.697
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MH976509	Gordonia phage Bizzy, complete genome	17308-17340	10	0.697
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MH651168	Gordonia phage Ashertheman, complete genome	17407-17439	10	0.697
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MH976513	Gordonia phage Kroos, complete genome	17872-17904	10	0.697
NZ_CP019304_3	3.4|4855935|33|NZ_CP019304|CRT	4855935-4855967	33	MK967396	Gordonia phage Tangerine, complete genome	17000-17032	10	0.697
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MH450129	Gordonia phage Ribeye, complete genome	18335-18367	10	0.697
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MH976509	Gordonia phage Bizzy, complete genome	17308-17340	10	0.697
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MH651168	Gordonia phage Ashertheman, complete genome	17407-17439	10	0.697
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MH976513	Gordonia phage Kroos, complete genome	17872-17904	10	0.697
NZ_CP019304_3	3.8|4856151|33|NZ_CP019304|CRT	4856151-4856183	33	MK967396	Gordonia phage Tangerine, complete genome	17000-17032	10	0.697

1. spacer 3.11|4856313|33|NZ_CP019304|CRT matches to NZ_CP039693 (Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence) position: , mismatch: 6, identity: 0.818

accgtccaggcaggggtcgccatgc---cgaacgga	CRISPR spacer
gccgtcaaggcaggcgtcgccatgctgtcgaac---	Protospacer
.***** ******* **********   *****   

2. spacer 3.11|4856313|33|NZ_CP019304|CRT matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 6, identity: 0.818

accgtccaggcaggggtcgccatgc---cgaacgga	CRISPR spacer
gccgtcaaggcaggcgtcgccatgctgtcgaac---	Protospacer
.***** ******* **********   *****   

3. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MH976511 (Gordonia phage Gaea, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .** 

4. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MT723937 (Gordonia phage JKSyngboy, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .** 

5. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MH450129 (Gordonia phage Ribeye, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

6. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MT723941 (Gordonia phage YorkOnyx, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .** 

7. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MH976509 (Gordonia phage Bizzy, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

8. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MH651168 (Gordonia phage Ashertheman, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

9. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MH976513 (Gordonia phage Kroos, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

10. spacer 3.5|4855989|33|NZ_CP019304|CRT matches to MK967396 (Gordonia phage Tangerine, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

11. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MH976511 (Gordonia phage Gaea, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .** 

12. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MT723937 (Gordonia phage JKSyngboy, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .** 

13. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MH450129 (Gordonia phage Ribeye, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

14. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MT723941 (Gordonia phage YorkOnyx, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .** 

15. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MH976509 (Gordonia phage Bizzy, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

16. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MH651168 (Gordonia phage Ashertheman, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

17. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MH976513 (Gordonia phage Kroos, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

18. spacer 3.6|4856043|33|NZ_CP019304|CRT matches to MK967396 (Gordonia phage Tangerine, complete genome) position: , mismatch: 7, identity: 0.788

gtcgtccaggccgacgggactatgcccgccaac-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcgtacg	Protospacer
 **** ************** *** *.**  ** 

19. spacer 3.9|4856205|33|NZ_CP019304|CRT matches to NZ_CP010683 (Phaeobacter piscinae strain P14 plasmid pP14_b, complete sequence) position: , mismatch: 7, identity: 0.788

accgcccaggcaggggtcgccatgccgaacgga	CRISPR spacer
cgcgcccaggcagcggtcgccatggcgcgctga	Protospacer
  *********** ********** ** .* **

20. spacer 3.9|4856205|33|NZ_CP019304|CRT matches to NZ_CP010718 (Phaeobacter piscinae strain P18 plasmid pP18_c, complete sequence) position: , mismatch: 7, identity: 0.788

accgcccaggcaggggtcgccatgccgaacgga	CRISPR spacer
cgcgcccaggcagcggtcgccatggcgcgctga	Protospacer
  *********** ********** ** .* **

21. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MH976511 (Gordonia phage Gaea, complete genome) position: , mismatch: 8, identity: 0.758

gtcgtccaggccgacgggactatgcccgccaat-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .*. 

22. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MT723937 (Gordonia phage JKSyngboy, complete genome) position: , mismatch: 8, identity: 0.758

gtcgtccaggccgacgggactatgcccgccaat-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .*. 

23. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MT723941 (Gordonia phage YorkOnyx, complete genome) position: , mismatch: 8, identity: 0.758

gtcgtccaggccgacgggactatgcccgccaat-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .*. 

24. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MH976511 (Gordonia phage Gaea, complete genome) position: , mismatch: 8, identity: 0.758

gtcgtccaggccgacgggactatgcccgccaat-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .*. 

25. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MT723937 (Gordonia phage JKSyngboy, complete genome) position: , mismatch: 8, identity: 0.758

gtcgtccaggccgacgggactatgcccgccaat-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .*. 

26. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MT723941 (Gordonia phage YorkOnyx, complete genome) position: , mismatch: 8, identity: 0.758

gtcgtccaggccgacgggactatgcccgccaat-	CRISPR spacer
ctcgtgcaggccgacgggacgatg-ctgcggacg	Protospacer
 **** ************** *** *.** .*. 

27. spacer 3.9|4856205|33|NZ_CP019304|CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 8, identity: 0.758

accgcccaggcaggggtcgccat-gccgaacgga	CRISPR spacer
accgccctggccggggtcgccatggtccggcgc-	Protospacer
******* *** *********** *.* ..**  

28. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MH450129 (Gordonia phage Ribeye, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

29. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MH976509 (Gordonia phage Bizzy, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

30. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MH651168 (Gordonia phage Ashertheman, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

31. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MH976513 (Gordonia phage Kroos, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

32. spacer 3.4|4855935|33|NZ_CP019304|CRT matches to MK967396 (Gordonia phage Tangerine, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

33. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MH450129 (Gordonia phage Ribeye, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

34. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MH976509 (Gordonia phage Bizzy, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

35. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MH651168 (Gordonia phage Ashertheman, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

36. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MH976513 (Gordonia phage Kroos, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

37. spacer 3.8|4856151|33|NZ_CP019304|CRT matches to MK967396 (Gordonia phage Tangerine, complete genome) position: , mismatch: 10, identity: 0.697

gtcgtccaggccgacgggactatgcccgccaat	CRISPR spacer
ctcgtgcaggccgacgggacgatgctgcgtacg	Protospacer
 **** ************** ****.   .*  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	4827052 : 4884143	39	Bacillus_phage(25.0%)	tail,plate	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP019304|4827052:4884143|DBSCAN-SWA
CCTAGTCTTCCTTGGAGGAACTGGCCGATGAAAGCACTTCAACGGTGTGGGGAACGTGGGCTGGCTTCACAGAACTGATGATGCGCTCGAGCCGGGGCACGCTGACGTCCTTGGCGGCGTCGGCGTAAACCTTTACGTGCAGCTTCGCTGTGGCCTGGCCCGGGAGGTCTGCGCCGGGCGTCTGGGACCAGGCCGCACCGCCGCTGTCCTCGATGACGACGTCCCGGACTCCGCCGACGGCGAGCCGGACGGCATCGGCCAGGCCCGGGACCGTTCCGCGGCGCCGATGGATTTCTGCTGCATGGGCGACGACGTCCCGCCGTTGGTCCGTGGACCAGGAATCATGAACCCTGACCCCCACCCAGTCGGCCAGCCAGTCCAGGAAGTCCTCGGGCGCCAGTCGTGGATCCAGATAACATGCCAGCCCGTCCAGCGTGGTGAAGACCGGGGCGAGCGCATCGTCGAAAGCCAGCAGAAACCGCTGCAGGAAGGCGTCCTCCTGCAGTACCGCCGGAAGGCGGGAGGCCAGCGGTACTGCGCTGCCCAAGCCGGGCACCATGCCACGCATCTCAGGTTCCTTCCGAAACGCGGACCCTGTGATCAAACGAAAAGACCAGGGCATTGCGGTTGACTTCAATGCGCTGCTGCGGCTCTCCCCGCTTCCCCGTCAGGGGATCGGCGGCAAAGACGTAGACCTCGTCGACGATCTCCGTACCTGCAAGGCTCTGGAGGACAGCATGCACTTCGCCCGCATGGACGGGCCGGCCGAACGGCCAGCCTTCTCCGTCAGGCCCTCCACGGATCGGGTCGAAATAGCTGTAAAGGGCCCGCAGGGCGTCCACGCGCAGGCGTTCTGCGGAAACCCGGGGACGGGCGGTCAACTGCGCAACCACGGTCACACCGCGGTAAAACGGCGGTTCGACTAGCAGCCGGGCACCAACGGGACGGCGCTCATCCAAGTACCCGGCAACTTCGGCCAGCAACCCGGAATCAGGAACGAGGTCACGGAAGGTGAGCCGTCCATCCTTGTCCGGAACGGCCCCCGGCACCACGAGGATCCTCACCCCACCTGCCTCGTCAGCGCCGTCGGCTGGTATGCACCGCACCCTGGCAATGTCCGGGGCGGCACGCTTGGCGAGCTGTTCGTAGTCCTCTGCGGTAATGGCGCGGTCCCGGGTTCGCAGTGCGAGAGGGCCGCGTTCCTTTGCCTGCTCGATCGTTTCCCCCGCGACGCCGCCGTGAGCGCCGCGGCGGTTTTCCACGCTGTTGACAAAGGGGATGGAGGAACGCAGCACGGAGAGCGCCCGCGCGGCAACGTTCCCCCGTGGACCGCCTCCGGTGCTGTAGCACGGAATGCGAATAGGGCTGCCCGCCGGCGGCACGGCGCCATAGCTGCGGAGGGATCCATCAGGCTCCCGGACGGCCGGTGGAAAATGCACTACGCCCGTTGTCCGGTCGAGCACCATCACGCGGTCACCGGGTTCCGATCCGGCAAAGGAGTCGACTTCAGTCCACGTCTCCCAGCCGGAGCCGGCGGCGACTTCAACTACGAAGCCGTCACCGCCAGGCAGCACAGGGTGCCGGCCCAGTTCGAAGGACTGCCCGGGCACGCCTTCAGACATCCCGATCACCTCGTCGTAGATCGCCTCGGCGTGGACGGCGGGAACGGAACCGCCAATTGTAAACGCGGCGGCGGAATGCACAGTAGGGGAAGCGCTGTAGGACGGATAGCCGGCAAGAGGTTCCACCACACGGCACCTCAGCCATCCCGCCCGGGTGCCTCCCTGCACAGAGGCCGCATGTCGGTGTGGCAAATGGACCACCACGTCACCGGGACGGTTCAGCCCGCCCGTTCCGTCGCTGTCCAGGTCACACGGCACCCATGAGTCGCCGTCCCAGGCCTCCCAGACCAGTGGCGGATTGTTTGGGTTAACACCCACGCCCCTGACCTCGCACTCAAACCGCAGCACAACCGCACAGGAGGGTGCAGCGTCGTTCAATCCGAGCAGCAAGGCGTCGCCGGGCACCGGCGGCGAGCCGAAGCACGGGAAGCTGCTGTCTCCATGCAAGGCCTCAGTCCGGGCCACCGTTACTGCGCCGTCCGTCTGGGTCAGGACGTGTGCCAGCCGGCGCGGCGGTACGGTAAGCTCGCGGGTCGTGGCAAAAACGACTGCTTCCTCTTCCTCGGTGCGCCGTGTGGAAGCCTCAGTCCCCTTGGGTATGACGACGGCGTCGGGCTGCGGCGCCGATAGCCTCATCAGGAGCTCAACTGATGCAGCGGTGGGCGGATGGAGTGTGACGCCGAGCAATTCCAGGAACGCGATGTACAGGCGGTCGGGCACCCGGTTTAGCCGGTAAAAGAGCTCGTCCACCATGAAGGCGAACGTTTCGATAAGGGTTACGCCGGGGTCCGAGACGTTGTGGTCCGTCCATTCAGGGCAATAGTGCGCCACCATGCGCTTGGCATCATCCACCAGGTCCTGGAAACGGCGGTCATCAAGATTGGGTGAAGGGAGCATTAGGAAGCGGCCTCCTCGCCGTTGCGCGGAATGACATAGAAGGGGAAGACCAGGTTGCGTGGATCATTGGTGCCCCTGATGGTGTACTGCACGTCGATGAGGAGCAGGCCGGCGTCCACGCCCTCGAAGTTGACGGCTACATTCTCCAGGGTGATCCGCGGCTCCCAGCGGTCCAGGGCCACCCGCACGGCATAGGCGATGTCCCCGGCGGTTGCAGCGTTCGCGGGCGCGAAGACGTAGTCGTGGACGGAGCAGCCAAACTCCGGCCGCATGGGCCGCTCGCCGGGAGATGTCGCCAGGATGAGGTGGATGCTCTCCTCGATTTCACGCTGATCACGGACCAGCGCAATGCTGCCGGTGCGGTCCGTACGCAGCGGAAATGCCCATCCGGCACCGATGAACTCCTGCCCCACCTTGTTGCCCTCCTGCCGTTTTCCTGGCGCAGCTGGCGGCCAGACTCAGTTGATGCGGACCAAGCCGCCCTTGACGGTGGTGGTTGCGCCTCCGGAAAGTTCCGCCGTCGCATCCCCCGCCACCTTTACGCCCGGGGCTTTCAGCTCGGCCGTTGCGGTGCCCGAGATCTTCACCGCCGCGCCCTTCAGCTCAAGATCTGATAGGGCTTCCACGATGACCTTCTTGCCCTTAATCGTCACCTGGCCCGTCGTCGTCGTTACGGCAACGTCCTTCCTGGCTGTGACGTTGACCGGTCCTTCAGAGACGATCTCGATGGCCGCATCCGGTTTCTGGACGAGTGCAATCTTCTGTTTGCCGCCGCTGGTGCTCACCAGAACCTGTTCGCCGTCCGGAGATTCGAGGAACTCCACTAGCATCCCGGTGCGCGAGACGAAGGCCCGGCGGGTAACAGAGCCGTCGGTTGAGCCCACGTGGTCTGCCCACGGTTTGTCCGGCTGATCCTTGCCGTTGTACAGGCCGCCGAGCACGAACGGCTGTTGAAAACTGCCGTGGCCAAAGGCCACCAGGACCTCATCCCCCACTTCAGGGAGGACGACGGCGCCCCGCGAGGTCCCGGCCCCGGCCTGGATGGTGCGGGCCCACCAGCTCTCATAGTTGTCAGACAGGACGGGGAATTTCACCTTGACCCTGCCTTGGTTTTCCGGGTCCTTGGCCGCTGTGACGACCGCATTGACCACAGTCGGCACGGCGTCGCGGCCGTTGCCGCCAGCGGCTACCCCGTAGAGGGAACGCTCTGATTCGTGGCTGACGGTGAAGGTTGTGAGGTAGCCGGTATCAGGGCTGAATTCGTGGCGGGATGAGCTGAGTGTGTACTGGCCGTCGAAGGGCTTACCGGCGCCCTTGAGCACAACGGCAGTGCCGGCCCGTAGCTTGGGGTTGCCCCTGGCCAGGCCCTCGACTTCCGCGAAGGCTCCGCCGAGCCGGGAAGCGATGGAGGCTGCGGCAGCGTCGCATTGTGCGGCCTGGTCAAAAGCGGTCGGAGGCGCAACGTACCTGGGGCTTCCGAATTTCTTGGCGAGGGCGGCCGGGTCCACTTCAGGGAGCCTGGCACTGCGGGTCTGCGCCTGCGCGACGGCCACAATGGCCTTCTTTGCGGCGACATCCCAGCCCCGGACCTCCACGTCGGGGACCTGGTCGGCGGAGGTGACAGTGCCGCGCAGCGCTACAAGGTTCACCCCGCGCTCCAGGACCAAGGGGTCCTCCTTGGCCCCGCCGGTTCCTGCCGGGGCAGTGGCTGAGTCTGTCGACGGCGTGAAGTGCAGCTCACCGCCGGACACGGAAAGGACCACGCCGGATTCGACGGCGAGCCGGTGCAGGAAGTCCCAATCGCTGATGCCGTCCTGCGCCACATGCTGCAGGACAGGCCCCTTCGCAGCGATGGTTCCCGCCTTGATTCCGGCACGCTGGGCCACCTTCCGGACAATGTCCGCCGCCGTACTCTGCAAGTACGCCTCAACGCGCCGTCCGCGGAACAGTCTGTGCGAGTGGTCCAGGCCACGGACGATTGTGTATAGGCCCTCGTGGTCCATTTCTGTTTCCAGCGCGGTCACCTCGCCGGAAAGCAGCGGGACCGGACCGCCGGGCCCGCTCTGCTGCACGGACAGTTTCACGGGTGCACCGATAGCGAAGCCGGCCTTTTCCAGGACGAGGGAGAATTCATCGGTGAACCGGAGCAGGAACAGGTCCGGGACGTTGCTGCTGTCGTCGACATAGCCGGCAACGAGCCGTGCGGCCACATCGGGCGGGAGCGGCCGGCCGGCCACCTCCACCAGCAGCATGTTGCTGAACTCCTCGTTATGCGCCACGGACCACCTCCGGCATCCGGCTGCCGTTCGCCGGTGTCCCGGACGCGAGCTCGTCGACGGCGGGCAGCAACAGGGAACTGCCGGGACGGAGCCGCATGGGGTCATCGATCCCGTTCGCAGCTGCCACCGCCCGCCACAGGGATGGATCGCCGTATTCGCGGTAAGCAATTCCTGCCAGGGTGTCCCCTTCCACCAGCGTGTGGACCCGCCGCGGCACGAGTCCGCCGGAACTGGGGTTCTGCTTGGGCGGGTCTCCCGATATTTCCTCCAGCGTGACGGTGCAGATGGCCCGGACCGGCAGTCCAGCGGCCGTGAAGAGCGTGTACTTGGCCTGCACGCTGGATACGTACGCATGGAATTCCGTGAGCTTGCCCCATCGGAACATTACCCATGGCGGGGAAGCTTTTTTCTGCTTCAGTGAAGCTTCGGTGGGTGTGCAGCACGCAAACAGCGCCTTGACCCGCTGGACCACGGCGTCATCCTGCTTCCCGGAGGCGTCAAAGAACATCTCCAAGGACAGTTTGGAGGGCATGGGTCCCGTGTACTGCGGCGGACCCGCCTTGCCGTTGCCCTTGGCCTTTTCCCGGGCCCAGGAAGCTGACTTGCCCATGGTGAGTTCCTTAGGGTTGAACTGGAAATCAATCTGTCCGAGCCGCGGGCCCGGTTTGTCCAGTGATCCGTCTAGGGACGGTTCAAAGAGCTCCAGGTATGCGTGCGAAAGCTCGAGCGCCTTTTCCCCGCCGCGTCCGCCTGAGCCCCCGGCAGCGGTGGCAGCCGGATTGGTGGACCCAACCGCGCCCTTGGCCGGTGCCGGGGCTGCAACTGTGGCCACGTCTTCCTCCTCTCGTTAGCCGAGTTTGGCGACAAAGCCGTGGTGGGCGATTTCCAGGGTTTCCATGATCACTTTCGGCTGGTCGGGGTTGAAGGAGGGCCCTTTCCAACGGACGGGAACGACGTCGTAAAGTTCCCATCCGGCAATCTTGGTGCCGTTGGCGGTCATTGCTTCGATGGTGCCGGTGCAGCGGGTGTAGCCGGAGGCCATGCCTGCGAACCACTTGGCAATCTTCTCCGTGTCCTTCCCCAGAGGCCGGGTCAGGGTGATGTTCGGGTACTTGAGGCGGGTGGGCAGCTGCCAGATGAAGGCGTTGTTGCCGCCCTCTTCCCGCGTTTCAAGGACCACTTCGCAGCCGAGGCCCTCGCACGTGGAAAAGGTGCCCAAGTCCGCGTTGTCCAGCGCTACCGTGTAGCGGACACTGACGGCGGTGGCGACGTCCTCCAGCATGGCTTCCTCAATTCGAATCGGTACGCAGTCCGCGGCGCTCGCGGTCCAGCAGCATTTCGGCTTTGATACGACGGATGAGGGGCCCGGCCAGCCGTTTGGCCAGTTCCTCCAGCTGATCCGGGGTGACGGCTAGCGCCGACCCTGGCTTACCCGCCGTCGAGTGTTCCGTTGCCGGAGAGGCTGTGCCCACCTGGGGCGCCTGGCTGGCCTCTTCGGGTAACGAGGCAGCGGAGATCCCGGGCTCCGTGCTGCCCTGCCCGGTTGCTGCCCGGGCTGCATGGTCAGGGCCTTCCGGCAGGCTGAGCCGCTGGATGGTGCCGCTCGAGTCCTCTGCAGGACCGGTCGCTTCACCAGCCCGCGGTTCCGCTGCAGGTGCGGCCAGCGTCAGGGCAACTGGGTTCGGGGCGATTGGGTTCGGGGCGGGAGCATAAACGACGCCGTCGCCGTTGGTTTCGCGGGAATTAGAACGCGAGGGTGAATGGCCTGCGCCGGCCGGAACGGCTCCGCCGAAGTCCACCGTGCGTTGCAGGGACTGCACGGCCAGAGGCCGGATGCTCTGAAAAACACTTCCGACTGCGGCACTTGGCTTGGGCTCATCGGTCACCTCACCCAACGGCATCAATTCGTTGTAGCCGGGGGCGGCAGGACCACTTTCCCCTTGCTGGTAGCCGCTGTCTGAGTCGGCGCGGTAGGCAGCGGGCATCCGTTCGGGCCCGCTCATGCCCTTCGCCATGACACCGGCAGCACTTGAGCCGGGTGCCACGTCCCCGCCTTGGCCCGCAAAAGCACCCTGAATTGTGTGCGCGGAAGGGGTCAGCGGAACAGTCGATGCCGCAGGCTGCCGGACAGTCGGAGGGTTTGCCGCCATGCGCTGCCAGACCTCGGCCGTTGAACCACTGAGCGCTGGGCGGGAGGCACGTGGGATTGGCGCAGCACTTGGGATTGGCATAGCGCGTGGGATTGGCAGAGAAGGGGCAGGGCCAGAGGCCTGCGCTACGCGCTGCACCGTCCCGGCCGACGCCACCGCAGGCGCCGCCGATACCCAGGAGGCAGGAGATTGTGAAGCTCCGGCCGGCGCTCGCTGGCTGCCGTAAACGGCCACCGGCCCCGGCAGGTATGTCCTTGCCCCCCAATCGGGTGAATTCACCTGCCCGTACTCCGCCCGTTGAACAGGGTCCCCCTTTTGAACTGAGATCCCGTTTTGAACAGGGATCCCGTTGCCGGAGGGAATGCTGCCGTACTGAGGCTGCTCAGGTGGCCCGGTTTCACTGAGGAGATGACCGCTGCCGCCGAGGAGCTGACCGCTGACCACGGACGAAGCGGTTTCACCCGTTGAGATGAGGCTCGGCGCTGGCTCCGGGGCGTCGGGCACGTCGCCGAGATGGTCATCGGGCTGGAGCATCGAGGCAGCAACTTCCCTTGCCTCAGGTCCGCTCGTCTCCGGGCCGCCGTTCAGGCTGAGGTGCTGTGCCGGTTCGGCGGGAGTCAGCCGGGCGATGACAGGAAGGTCAGCAGTACGTTCTCCGGGAGACCGCTGGACGGGATGCCCCTGCAGGCCCGTTCCTTCTGCCGACGCAGTTGACGGCGCGGGCGTGGCTTCCGAAATCAGCGGCGCTGACGGCTCTTCTGCGGTCACCGGCTGCGAAGGTTGCAGGAGCCCGGTGGCCCCAGTCCCAGTGCCCTCGCCAGACCGGGAGACTCCGTCGCCAATCTGGTCCATGGCCTGAGCCGGGGCCGCGGCAGCTGCATCCGCCGGCGTGGCGGCAACGGCAACGTCGCCTGACTCCGCACCGTCATCCACGCTCCCGACGCCAGACGCCGATGACCGGCTGTCAGGGGCATTCCATGATTCAGAAACACTGACGCCAGGCGCGGCGGTTGCCCCCACCGCTGAAGCGGCGCCCGGCCTTGAGCGGGACTCCCCCGGATCCATCCGCTGTACGGGCGCCGCCTCAGGCGACACGTGCGTCCGCTGCACCGGCGAGACGTCGTCGTGCCCGTGCCGGGTGGGGGTGGTGGACAGGTCACGGGATTCGCACTGCGAGAACGACAGGGGGCGCCCGAGCCCTAACCGGCTGGGATACGGGGATATTGACACGGGCGGCAGGGCCGCCGGAGCCTGGACCCTGTCAGTGGTCCTGTCTTCAGCTGCGCGTTGAACGGCAGCAGGACCCGGCAGCGACACGTACGTGGCACTTCCGTCCGAGGCGCCGTCGGTCAAGTTCAGCCGGGATGCAAGCGCGATGTCCCAGCCGGTAGTGGCAGCTGATGGCGTGTCTGGTTCAGTGATTCGTTGTTCGGCGCTAAGTTCCGAACCGGGTTTGATCGCCTCCGGCGCCGCGAGGGGAAACGCGGGGGCTATGGAACCGGCCACTCGAGTTTGCGCGGCCCGGAGAGGCTGAGCCTGGCTAGGGGCTGCGGTTCTCTGTACGGCTGCCGCCGGTTGAACGGGGGCCGGCAGTTCCCCAGCCAGCTTTCCGCCGTCGTCAACCGCCGTTTCCGGTGCTGGACTGGCACCGGCCTCCGGCATCGTCGTGGGACGCTCTTCTGCGTCCCACACCCCCAACTCGCCCACGTCAGCTTCTTCCGGTGCCGGGGTCGGCGGCGAAGCCGGCGCGGCCCCCGGTGGGGCGTCCGCCGTGACTGTGCTGCGCTGCACCGCCGTCGGACGTTCCGTCTCGGCCGCAAATCCGCCCGTCCGGTGTGAGCGGGAGGGGGGAACGCGCAGCGTCATCTCGGGCGGCTCCGAACTGTGCGCTTCCCCGGTAACCGTGCCGCCGCCGTCGACGTCTATCACCCCCGGCGGCGCGTCATCGGACACAAAATGGCTCATGGCTGAGGTGAAGGACGGGTTGGTCCATGCGGCAAGGGAGGCGGCAAAGCGGCCCGGGCCGTGCGTCAGTTCCATAGGGCCGATGGTGCGCTGGAGCGGTGGCAGGAAGGCCCAGCCGGCGGGCGGTACCGGCAGCGGCTGCGCTACCGGTGGTGCCACCGCGTCGGGCGCAGATGTGGGGGCCCCGGGTTTGGGGCGCTCGCGTTGCCAGGGCCACCGCACGGTTCAGCGCTCCTGTGAAAGCCGCGTGTTGATCCCCGCGATCTCCCGGACATAGCGGAGCCGCTGGCCGTGTTCGAGGTCGAGGATGTCGTCGAGGGGCCAGTGGAAGTGATATGCCACGTACGCGACCTCCTCGTAGATCCTGTCGGCCGCGTACGTCATGATTCCCCCAGGCGACCACCGGCAAGATCCGCTGTGAAGCGGTGTGAGCACTCCGGGCAGGTAACGGCGATGCGGGTGTGGCCTTCGGCGTTGATCCTCCGGTAGAAATCCTGGAGGAAGGCGACGTCGGAGGCGAACATGTTTTCGACGACGGCGGAGGTCACGGCTGCCAGCGTGCCGAGTGAGGTGATGACCCTGCCCAGGAGCACTACCGTTGTGTAGGCCGCATTTTCTTGGACGCGGGCGTCGTAGAGCGGCAGCAGTTCGTCCCTGGCAGTGGCCAGTCGCATCACACCCGTCTTGTGGACGGTGCCGTCCTGGTCAACGTAGCCTCTGGGAAGCTCAAAGCTAAATTCGGTGCGAAGCGGCTGTCTTTCTGCCGCGCCGGTGGCCGCCCTTGGCGCGCCGGGACTGTCAGCCTCCAGGTCCGGCAGCACAGCGGCTCCGTGTGTGCGTTGCATCATGAGATGGTGGATTCGTCGTAGCAGATGACGAACTTCTCGGTGGCCTGCTCGGTGGCCCCCGCCTTGAGCGAATTCAACTCAACGCTTTTCACCCAGCAGTTGACGAAGTTGTACGTCTTCAGGGTTTCGCCTTTGTAATCGAGCAGGGCGACGGCGGCTGTCTTGCGGGCGCCGGCGACGTCGCCTTCCATGACTGTCTTGAGCCAGTCGGTGATGGTCTTGCTTTGCGTCAGACCACGCGTGACGGTCAACTCCCCTGCCTTGGGCCGGCCGATCAGCTGGCGGACAACATACTTGCCGTCCTTCGTCTGCTGCTTCAGCTCGATCTTGTCGACCTCGGTCTTGAGGCCGCTCACCTCGATCACCCTTGGCACTTCGATTCCGTCAATGGTGACCGTGAATCCATTTGCTGCTGAGTTGTCAAAATCGCCGAGGGCCATGGTCTTGCTCCTTTTGAACTGGAATTACTCGCTCACGAGGCTGGTGCCGCCGGAGAACTGGGAAAGCTGGAAAATAACAAACTCCGCCGGTTTCACCGGAGCAACACCGATCTGGCAGACCACCTGGCCGGCGTCGATGCCCTCCGCCGGGTTAGTTTCGGCGTCACACTTGACGAAGAATGCCTGCTCAGGGGTGACACCGAAGAGAGCGCCCTTGCGCCATTCGTTGGTCAGGAAAGCGCTGATGGTCCTCCGGATCCGTGCCCAGAGGGCGGGATCGTTGGGTTCGAAGACGGCCCACTGCGTGCCCTGCAGGATGGACTCTTCAAGGTAGTTGAAGAGCCGCCGGACGTTCAGGTAGCGCCATTCGGCGTCGCTGGAGAGGGTACGTGCGCCCCAGACGCGGATGCCGCGGCCCGGGAACGTGCGGATGCAGTTGACGCCGATGGGGTTGAGCAGTTCCTGCTCCGTCTTGGTGATCTGCGTCTGCAGGCTGGTGACGCCGCGGACCACCTCATTTGCGGGCGCCTTGTGCACGCCGCGGGTGTCGTCGTTGCGGGCCCAGACCCCTGCCATGTGGCCCGACGGAGGGACGAACCTGTTGGTACCGGTGGCGGGATCGAACACCTTGACCCATGGCCAGTAGAGCGCCGCGAACTTGGAGTCGAAGCCTCCGCCGTCCATCCGCCAGTCCTTGATCTGCTGCGCGTTGAGGTTGGGCGGCGGGTCGATGATCGCGACGCGGTCCCCCATCAGCTCGCAGTGGGCGATCGCCGCGAGCTGGACGGCCTTGAGGGTTTCCGCATCAATGGAGCCCTGCTCATAGGCGGCCATCAGGTCCGGAACAGCGACCATGGTCACCTCGTCCACCGCCTCCAGGCCGCTGAATCCGGTGCGGTCGGCGGCGTCGCCGACGTAGTCGTCGGCGTTCAGTTCGTCAGCGGTCGGGGGCTCTGGTTCGGGCTCGGGCTGGACCAGCTGGATGGTGCCCTTGTCCGGCTTGACCAAGGCGCCGCCGGTGGCGATTTCCTCGAGGGTGACGATCTTCGATTCCGCGCTGACCTTCGTGGCTGCGTTGTTTGGGCCCCGCTTGGTGGTGACGTTGTCCCAGACCTCGGGTGGCTTGCCCTCGACCGTGATGACGATCTTGAACTGGTCCTCTGACGGGTTCTCGCCGCCGGCGTCGGCTATCTCCACGGAGACGGGCTTCGGGTTGGCCGCGTTGGATTTGGCGGTCAGCCGGTAGCCGCCTATTTCGGCGGTCGGCGCGGCTGTCACGGCCTTGGGCGCCTGCTTCGGTTTTTCGTCACGTGCTCCGTCGGCCCCGATGCGCACGACGTAGCAGTTTCCTCCCCCGTTGAGGAAGTAACCGTAGACAGCGTGGGCAAGATACGAGCCGGGGATGAAGTCCCCAAAGGTTTCGGCGAACTGCGTCCAGTTGGATACCAGGGTTGGTTGGTTGTCGGGCCCTTTCGAGGCGAGCCCGACGAACGCGGCGACCGCGGTGCCTACCCCTTCGATCGGCCGAGTGCCTGCCTCAACCTCGTTCACGTACACACCGGGCGAAAGATAGTTCGGCATTTTGTCTCCTCGTTGAACCCAAAACGTGGTTCAAGGGTCACGCCGAGACGGGGTGCGGCGGTACGGCTATGCGGATGCGCTCACGGGAAGGATGGGGTGCACGAAGGGGCAGAGAGCATTCGGATTCGAGGGCGCGTTCACAGTGAATTAGCAGCAGCTGCAGGTGAAGAGGGCACACCTTCCGATCAGAGCTTTCGCTCTGCGACGGTTCCACGGCAGGGACGCTTGAGGTGGATTCTAAATCCCTCTGCGTGCTTCACCATAAAAGTCTCGTAGCAGCTTGAGCATCGACTCTTTGGTGGGAACTAGGTGTGGAGTTGCCATGCCGTGCGCCCGCAACTCCTGCGCTATGTGTGTCTGTGTTTGGAGGACCCAGGCAGACCAACGTTGCCTCACTTGGTCAACGAGCATGGTGACCCTCACCTGACTGCGGGCGATCGACTCTGACTTCAGTCGCCCGGAGTCTCCAAGGGGCAGATGGGTAGCTGGTCCGAGCGCTGACCCACTCGCCATCACCTCGCCGAGATTTGCGGCACCGGATTGAACCAGCGCATGAGACATTGCTGTTGTCGTCGCGATCGGTTGCTGTACAAGTCCAAACCCTCTGTCTAGGAATCGAAGGGGCTCGATCACGTGCGTCAATTGCGTCACTGCTCGCAGCGCGGCACCAGGTGGCAGAGAACTTCGACCCGTTCGCATAGGCGCGTTCGGATCGCCATGGAACCCATGGGCCACCAGCAACTCGGGCGTAGGAGTGCGACCTTCTCGGGAAATCAACTGCATTAAGCGACTGATCTGCGCATCTGTCATCCCGTTGTCCCGGAGGTTTCGGACCACCCCCATGACCTTGCCTGTCTCAGCGGTCGCCGACGTCGATCCGTAGGCGCCAACTTCGTTCAGCTTGACGTTATGTGGCTGGCTACGGTTCGGGTTCAGCATCTCGGTCAACTGGCCGCCTGCCGAGGAGGACGTGGCAATGGCGAAACGTGGAACGTCGCTCGAACCTGACTGACGGTGGGCCTCCAAGGCGCCACGTCTCGCCACAATCTGTTCAGCGCTTGAAAGGCCTTCGACCGAAGCTGGGACGTGGGTGGTCGCTCCCATGGCCGGGACCCCACGCCTGGCCACGGAACCCGCATACGCTTGCTCGTGCGGCCCCCGCACCACCAGTGCCGACGATCCCTCAAGCCCCGTTGCGAAAAACTGACGCTCCACCTCCGCCGCAGTTCGGGCAAATTCCACCGCAGCAATCGACTCGTCTTCGTACGCAATCACGTCTGTCAGCCGGACTGCAGTTGGGTTGATAGCACCAGATATAGCCCAATGCGTTCCCTGCTTGATGGGTTTGAGCTCGGTTAGACCGTACCTGAGCTTGACTACAGACAAGAGAGGCGCCAGTAGGCGGTTGGCAACCTTTCGCCCAGCGAATCGACGGACCGCCGACTCCGCGGCGGCCATGCCCATATCCAGACGCTTCTGCTTGCCCTCAGGCGAGTCGTCCCCGCCGCGGATCTTCGCCAGCGCCTTCTGCCCGAGCTTCTTCCCACCGGCCTTCACCTTGCCGGCAATCCCCTTAAGCCCCCGAATGATCGGGCCGGCCAGCTTCAGGCCGGAACTGATCACGAAGTCGAGGGCCTGGTTGACCGGCTTCTGGAGCTTCTGGATGATCTCGCGGATCTTCTGGCCGATGCCGCCCAGGCCGATAGCGCTGGCCAGGAAGCCGATGAGGATCGGAACCATCTGGCCCAGGACGTCCTCGATCTTGTTCACCACGGCGCTGACGTTGCCGCGCACGACGTCGGCGACCGAGTCGATGACGGTGTTGACGAACTTCATGATCCGCTCGGCGTTGTTGACGAAGAACATCACGACGTCGTAGATCAGCTTGCAGGCCTTGATGAATGCCGCGGCCGGGTTGAGCAGGCCGATCAGCCACGTGATGCCCGCGGTGATGATCTTGGTGATGACGAAGTCCTTGACCTGCTCCAGGATCATGTTCTTGACGTTGCCGAGCTTTTCTAGGAGCATCTGCCACAGTCCCGCCAGGCCCTGGCTCGCGATGACCTGGAAGATCTCCACGCCCTTCTCCACGGCGGCCATGGCCGGCTCACCGATCTGCTTGACGAGCCGGTTGCGGATGTTGGTCCACGTGAGTCCGAAGATGGAGGCCAGCAGCTTGATGATGCCCTTGACGTCGAACGTGTCCGGAAGCTCGATCCCGCCCTCGGCCAGCGCGCCGAACAGCCAGCCCATGAGGCCCTTCTTCAGGTGGCTCAGGATGTTGTCCTTGAACCTGAGGATGCCGCCCTTGACGCCCTCGATCAGATGGCCCAGGAAGGCAACCGGGTTCTTGATGATGTCCCCGACCACTCCTGCCGCGCGGGATAGGACGTTCCGAAGCATCGAAGCCAGTTCGCGGATGGTGTTGACGATGGCCTTGATCGCTCCGATGGCCTTGTCGACGAGGCCCTTGTTCTCCGCCTGCAGCGCCTCGATGCGCTCGTCCAGGCCCTTGCGTGCCTCGACGTACTTCGTCGCCAGGGCGTCCACCACGGACTCCTGCTTCGCATTGACATCGGATTCGAGCTGCGAAAACTTGTCGCCGATCTCCTTGGTCGCCTCGGCACCGACTTTCTGCAGGCCAGCGGGCAGGCTCTTGACGTAGGCAGCAATCTCGGCCCGGCCCTTGGCAATGCGCTGCTTGGCCGCGGCGAGGTCACCACCGACGATGTCCGCAACGTGTGAAATCACGGTGTCCATCTGCTGCAGGTAAAGCTCCCGGCCGGCCTCGTAGAATTCGTTGACCTTGGCGGGCATGCCGGCGATCTTGTCCTTAAGCCACCGGTACCCGCCCAGCCAGCCTCCATACCGGTCCTTCTTATAGGCAGACATCTTGGCGTCGACATAGGCCTCGAAGGAGGCCCGCGCGCCGGCCTCGCCTTTCTCAAAGGCGGCCTCCACCTTGGGGTCAATCCCGTCCAGGATCTTCTTCACATCGGCTTCAGTGGCGGCAAAGATCCCCTGGACTCTCGCCGTGACCTCCGCGCGCCTGGCCTCATCCTTCGATTTGGTCTTCCCCTTGTCCGCCACGAGGTTGGCCAGCGCTGCCGCGCGGGCCCCCTGCATTCCCGTGACGCCTGCCGCCGTCTCCGCCGATGCCTCCGCCTTGCCCTGCTGCAGCACCTGCTGCTCCTGCTGGCGGAACTCGGCGGGGGCAGTTTGGGCATGCTCCGCGGCCGCCTGCTTGTCGGCCAGGCCCTGCTGGAACTCCGGTTCATTGGACTGGGCCAGCTGCTGGTCACTGACGCCGGCGTCGGCCATCTCCTGGTTGGCCTGGTGGGTGCCGGCGGCGAGGTTGAGCTGTTCCGGCGGCGCCGGCTTGGGGACAGCACCGGCTGCGGGGACGGGGGCGGCCTGGCCGGGCTGTTCCTGGGCCATCGGTGTGACTGGTTTCGGGACGGCCTTGGACTGGTCGGGCGGGGCTGCCGTGGCGGCCTCGATATCCTTGGCCTGGCCCTCCTCGCCCTGTGTGACGAGGCCCTTGACCTGTCCTTTTGCTTCCCCCGCCTTGCCAGACTTCTTGTACTCGTCGGCCTCCTGGAGCGTCTTCGGCGACTTCGCCTCAATGGCGGCTTTGACCGCGGCAATGAACGCTTTCTTGTCGAAGGACCCCGCCTGCTGGGCGTCCATCTGGTCGACTTTGGCCGCCTTGGCCTGGCCGGCCACGTCGTCGGATGGGGGAAGCGCGGCAGCCTGGGCCTCCTTGGCCTTGGAAGCGGCAGGAGGATGCGCCCTTCGCGACTGCGCCACTCCCTTGATAGTGCCGGTGACCTGGCTGAAGGCAGGATCCTCCTCGGGCCTGACCTGGGCCGGTGCCACGGGCGGCTGCAGGAGCTTGTCGGCGGACAGTGCGGCCGGGGCAACCGGCGCGACGCCCCCGCCGCCGGACACGGCCGCGGCCGGCGCCGGCGCAGGACTCTTCCCTCCTGCCGGTACCTTGCCCGGGCCGCCCGTTTTGGCCCGTGCGGCTTTTCCAAGCGGGCTGACCGCAGGCACCGGCTTCGGCGGCGGCACCGGCTTCTTCCCTGCGACCTGCCCTGGATCGAATCCAGTCCGAGTCACCGCCAGGGCCGCGGCAGGCGGCTTGGGTCCTTCCAGGTCCACAGGGATGCCGGCGGTGCTGGCGGCCTTAAGGCCCTTCTCGACCGTGGGGACGGCGGGCTCGCTTTTTCGGATCTCCGTCAGCGCTGCGTCGATCTCGGCGACAGCCTGCTCCCCCGGCGATTTCTGCTTCGCTGCCATGAGTGCGCCCACAGCCGCATTCCCGGCCTGACGTTGCAGCGCCAGCACGCCACGGGGATCCATGCCAGCCGCCGTCGGGCCGCCTGCCCGCCGCCTGCCCAAACTCAGGGCGCTACTAATTTCGCTTCTTGCGGCGCCGCTGGCAGGGCGCGAGGCGGCAGGTCCGGCGCGCTGCGCCGAAACCTTCCCCGCCTGGCTCTGGAACCCAGTCGACATGGCCTTCCCCGGCCGAACTAACCGGATTCTTCCTCTTCAGCCTCGTCGCGCTGGACTGCCGCGCCGGCCATGAAGGAACCTTGCGCCGTCTCTTTCTCCTCGTCCTCGTCCTCGCGCTGGACCGCCGCATCCTCCGCCTGGCGCTGTACGACGGCGGAACCCCCCTCGACGCGCTGGGCCGCCGGAGCGGCAGGCGCCGACATGGCCCGCTCCGCGGTTGCTGCCGCCTCCCGTTCGAACCGGTCCGACGGATCGCTGACCCGGACACCCGTGCCTGTGGCGGTCCCGTCCACCGGGCCGCTCCGCTGCTGGACCACGTGGGTAAGTTCATGGGCGAGCATCGTCCGGCCGGTGTCCGAGCCCGGATCGTATTTGTCCCGCTGGAAGACGATGTTGGATCCGACGGTGTAGGCGTGCGCGTTCACGGACGCCGCCGAATCGTGTGCCGCATCTCCGGTATGGACACGGACGTCCGAGAAACTGTGGCCCAGCCGGCCCTCCATGTCCGCCCGCACCGGCTCTTCCAGGGGCTGCCCGCCCCCGGAGGAAACGACGTCGAGCACGGGCGAGCGTTCCTCCTCCGCCACCCCGCGGACGCCGCTGTTGCCGACGGCGCGCTGAAGCGCCAGAATGCCCCGGGACCCGACGACGTCGGTCCGGCCGGCGGCCGCCGCCTTGTACAGCAGCGCCGGATCCGGCGCCTCGGCCCGTGGTGATTTGGCCCGTAAGCTGTCCGCGTCGGGCTGGTCGTAGTCGTGGCTGTGCATCGTGCGCCCCTTTCGTCGGACCTACACCGACGATCCCCCCTCCAGTCCGGCCCTACAAGCGCCGCCACGGCGCCGGAAGAGGCAGCCGTTTCTGCCCCTACGGGCAAGGCCGCGTGTCTCAGCCCATGGAGTTCTTCGCCGTCGACAGCATTCCCCAGTACGGGCCGAATTCGCTCTCCAGCATCAGCCGTCCCAGTTTGCGGTACTCCCGCTGCACGGCGGTGACGAGGTGCCTCATGGTGACGGTCCCGCCGTCGTCGGCTGCCAGGTAGGCGGCCGTAATGGCGGAAGAGCGGATGGAGCCGCCCGCCAGCTCAAACGCCTTCCCCAGGAAGGCGAGGTCGAGGTCCGCGGAACGGTCCAGCGTCCGAAGGCACCGGTCCCACAGCACAGTGCGGTGGGCGGCGTCCGGCAGCGGGAAGTCCACCAGGACATCCAGCCTGCGGGTGAACGCCTCGTCAATGTTGGCGCGCAGGTTCGTTGCCAGGATGGCCAGTCCGTCGAAGGTCTCCATGCGCTGGAGCAGGTAGGCGCTTTCAATGTTGGCGTACCGGTCGTGGGCGTCCTTTACCTCGGAGCGGCGGCCAAAGACGGCATCTGCCTCGTCAAACAGCAGCACGCCGTTGACTCCCGCCGCGGCAGCAAAGATCCGCTCCAGGTTCTTCTCTGTCTCTCCCACATATTTGTCGACGACGGTGGCCAGGTCCACCACGTAAAGGTCCAGTCCCAGCTCCCCGGCCACCACTTCGGCGGACATAGTCTTGCCGGTTCCCGAATCTCCCGCGAACAGTGCCGCTACCCCGTGCCCGCGGCCGGCTCCAGGACGCATGGACCAGTCGCCCAGCACCCTTTCACGGTGCCTGGCCCGCAGCGCGACCTCCTGAAGTGCCTGAAGTACCGCATCCGGCAGAACCAGGTCACCCCAGCCGACCGCCGGCTCGATCCGCCGGGCCAGCCGGTCCAGGGCCGAACCGTTCTCTCCCCGTGCCCCGGCCCGCAGCTGCGCCGCAGTGGCCCGCCCGTCCTCTGCTAAAGCCGCCTGCACAAGCGCCGATCCGGCCGCACGGACAACCTGCTCCGGCCGCAACCTGAAAGCCGATGTTGCAGCCTCCACGTCAAGCCCGTCATGTGACCCAAGGGCCGCCCGCCACAACTCCAGCCGCTCGTTCGAAGAACTTGCGGCAACGTCGACCAGCAGCGGCGGCCGGCTGGTCCACGCTGGATCCCATACCGCGTCACCGACGAACAGCACCGGCTGCGGTTCGGCGTGGAGCACTTCCAGTACCTGGGGGTGATCAGATATTGCGGCAAGGGGAGCTGCGACCAGGCCGGCGCCCCTGAGCCTTGCCTCCCGCACTGCGGCGTCCACCAGCGCAAGGGGTTCCCGCTCATTCGCCAGCCGTCCCAGGTCCAAGTGGATCGCCGGGTAACCGCTGGAACTGAGTGCCTCCGCCGCGAGAATCCGCCCGGATCCTGTTGCGGGTTCCCGCAGATAAGCCAACCGGATACCCGCGTCGAGCGCCCTTGCCAGGGGGCCCGGATCACCCCACGTGACCTCGGGGGGTGACGCCAGGACTGCGGCGAGCGCAGGATCGGGGGCATCATCTCCCAGCAGATGCCCGACGACGCGGTCCGGCACCCGCAGCGCCCTTCCAGGCAGAGGGCGGTCCGGATCCTCAACGGCCAGCAGGCCGCCCCAAATGAGTGGCCCGGACAGCAGGCGTGCGCGGGCGCCGGCGGCATAGAGCGGTTCGCCACACAGGGCCAATGCAACAGCCACTGACGGGCGGCGGCGCGTGACGTCATCGTTCAAGTACCCGAAGAACTGTTCGAAACGTGGATCCAGGTCGGCGGCGAGCGCCACCAGCAAGAGGTCTACGTCGAGACCTGACAGTCCGAATTTATCTGCGAGGTTCCGCAGCCTCAGCGGGTGACCCGCCGCCTGGGCCGTTTCAGCCAGTTCCTCGCATTCGCGGTACCGTGCTGACGCCGCACCCAGCCCGCCATTGCTGTTCCGCAGAGCGGGCTGTTCTCCCTCAAGCAGCCGGTCCACTGCCTCGTCACTGAGATACAGCCCCCGGAACGGGTCGTCAGGCTGCGGGTCCTCGGCGCGGCGCATCGCAACGAGGAGACGGATGCGCTCCTCGACTACGCTGATTCTTCCCAGCAGGTGCGCCAGGCTCGGATTCTGCCCCATACGGGAATCACCGGGCCTGCCGCTTGCCGTTGTCCCGGGCTGGTGCTGGCGGGGCAACGTGCTGGTGACGGCCGACGTCGGCTCCGCCATCCAGGAGGTCCGACATGTCAAGGTGCGTTCCCTGCGAGGCCGGCGGTCCGGCCTGGTAAACGATGCCCGTGTCGACGGGCGCGATAACCACGATGTCGAGCGACGGCTTCAGCTCGCCGCCCAGAGCGGACCAGACGTCAGCAAAAGCCCGGTCCTCCGGCGGGGGAAGCCCCACGGTCAGCGGCACCACGAGCCCGGTTTCCGCCAACTGGCCGACCACGAGCTCGTCAGGCAGGGCCTCGTACTTGAGGAAGCAGCGAAGCAGCTGGTCAAGGAGGCGGTGCTCGTCCTCCGGCCGTTGGGTCCACGCTGTCACGAGGTAGGACAGCTTGTAATGACGGGGGGCCGGACGCCGGGTCCGGACATGGCCGTCATCGCCGCGCTGCTCCGACAGGCCCCGTTCCCGGCGCCGGACGTCCTCGCGGATGTCGTACAAGTAGAGGTTAACCGTCGGTGCATTGCGGCGTGCAGCCCAGTCCTTCGTCGGAGCGTCAAAGACGACGTCGACTTCCGACCCGTTCAGCGCGTCAGTCCGGATGAGCGTGCGCAGCGCCTCGTCCACCTGGGCAATCACATGACCACCGCCGTCGGGCTGGCGTGCGGCAGCTGCGACCGCGCCGCCAAGGCACGGCCCGCCGTCGGGCAGGTGTGCGGCAGCTGTGATCGCACCGCCAAGGTACGGCACGCCGTCGGAATCGCAACTGCCAATCCTGGTGTGGACAACTCGTAACTCTCCCGCTTGCCGGAACTTACGGTCCGCCGCCGGACGGACCGTAAGTCCACGGTGCTCGACACGGTCAACCGCCGGAACCCCGAGGGGGGCAGGCGGCCGGGAAGCGCCTCATACCCCTTCGGGCAATCCCTAAATCAGCCCCTCGCGCAAGGCGTAAGCCACGGCATGGGACCGGTTGCGCAGCTGGAGCTTGGTGGTCACGTCGTGCACAACGTTCTTGACGGTGCGTTCCGAATACGCGAGCTTCCGGGCAATCTCACACGTATCCAGTCCGTCTGCCAGCAGTCGCAGGACCTCCACCTCGCGTGGGGCTAGGCCGGTAAACATGATCCCGCGGGGACCAAGGACGTGGCGCTGCAGCTTCCCGACCTGGTCCAGCAGGCGGCCCAGCAGATCGGGCGGCACGCTTCCTTCACCTGCAGCAGCGGCCAGGATGACAGAGATGAGGCGGTCCGGTGTCGCTTCGCTGCGGCGCACTATCCCCACTACCCCCGTTTCCACTGCTTTGACGAGGTCGCCGTCGTCCAGGCGGCCTGCCACGAGGACTGCCCGGGCGGCGCCTTTACGCTGCACGATGCGGAGCAGAGTCAGGGCGTCTTCGTCGACTGAATCTGCAACCACGACGACGACCCTCGCCTCCGCGTTCGGCGCCCGCACCACGCGGACTTCGGGACGGGCCCGCAACTCGCTGGCGACCCCGGCTTCGGAAATCGGATCGCGTGCGTGGACTTTCACTGTTATTGGTTCCATGAATCCTCCCCTGCTACCTGTAACGGCCGCGGATAAGACCGGTAGCCCCCACCAGCTTCACGTACCCGAATGTGGCAATCCGCTGCCCTGAATTTAGCGGATGCTTCTCTTCGTGCAGTCAACAAGGGCTCAACGGGCAACCGTAGTGCCCCGAAGTCCGGCCCGGTGTCATGCTGCGCGCATCCCCCAGCGCCCTAGCCTCTGAGTACCTGCGAGCGTCTCTGCCCAGGCGCTTGCTGGCCTTCGAAGGAGAGGGTATGACCACCACCGCATCGTTTGACACGCCTCGCCTCAGCATAGAGGGGGGTGCAGAAGGGACGACCGGTATAACCTTCCGCAATGACAGCGAAGTCGTGGAGGAATACTCGCTTCGGGTTGTTGGCCCGGCAGAGTCCTGGGCTGAAGTGGCACCGGCCCGCGTTTCGCTCTATCCAGGACATGACACCACGGCTGACGTCACATTCAGGCCTCCCCGGTCTGCTTCCGTGCACGCTGGCGAGTACCTGTTCGGGGTTCAGGTATTACCCACCGAGCACCCGGAGGACGCCGCTCTGCCGGAAGGGGTTGTAGAGGTGCGCCCCTTCCTTGAGACGACGGGTGAGCTCATGCCAAGAATGTCCCAGGGCAAGCGCGGGGCCAAGCACAATGTTGCCTTGGATAACTGGGGTAATGTCCCCATCACAGTGGAACTGGCTGGATCCGACCCCGGCGACCTGCTGGAATTCGAACTGCAGCCTCCGGAACTGACAATAGGACCTGGCGAAGTTCAGTTCACGGCTGTCCATGTTCGACCCGCAGAGAAGATTTGGAGCGGCACGCCTACCACTCGCGTTTTCGTGGTAACCGCGACACCGGAGGACGGGGTTCCCGTTCTACTCGACGGGAGCCATGTTCAGTACCCAATACTGCCGTGGAGGACCATCAAAACCGTATTTTGTCTCCTGCTTCTGGCGGCGGCACTGACGGTGGCGTGGCACTTCTCGGTCGAGTCAGTCAGGGTGAGCGAACCCACGAGCACGAACACGTCGCAGGGGGTCGCCCCGAACGGCGTGCCGAACGGGACTCAGTGATGCCTACTGGTCCCGCACTCCGGGTCGGGGATACGGCTTTATGCTCCTTGTCCGACGGCCCCAAGCCGCATGTGGGAGGGCCTGTCACCCCGGCCGCCGGCGTGCCAACCGTGTTGATTGGCGGGATGCCTGCTGCAGTAGCGAACGCCCTTCCCGGCGGGATTGTGTGTGTTTCTCCGGCGCCAAACGGGATCGCAGCGGGCAGCCTGACGGTGCTCATAGGCGGCTTTCCTGCCGCCCGGGTGGGTGACCTGAGCCTTCACGGCACTCCCGTGGGCCCAGGCCCCGGCTGTCCCACCGTCATTATCGGGGGGTAGAGCGGGGACGTAATACGTGGCTGGCGGCTCTGCTTGGGCTTCACTGTCCCTCGGCCGCGGGAACCGTTTCCGTCGAGCCCGCCGGCGAGGAAGAACCGTCGGAACCGCCTCCCTCCGGAAGCTGGCCTCCCTCCGGAAGCTGGCCTCCCTCCGCAGCAGGCGAGGAGGGACCGTCTGTGCTGTCCATTGTTTCTGGGGGGCAGACGGCCGTAGCGGGCAGGGTGTCTGCGGTGGGCAGGGTGATCTTCACGGTGATTAGGTTGTTGTCCTCGTCGGCTTCTTCAATGGTTTTCAGCGGGTCGGCCATGAAGGTCACTTCGTGCGTTTGCCCAAGGTCATCGGGCTGGATGTTGACGCGTACCTCCGTAAGCTTCGGTTCCTCCCCCGCCTCCAATGTTTTCTTCTCACTCAGCCCCACTTTTGCCGCTAACGACTTACTTTCGATTCCCAACTCAACCGCGTGGACCCCCTGCCCCTGGTTGCGCAAATCCACGGTGACGAACAGGCAGGCAGGCGTGTCGGGCGGGTCACCCCGGGCCACGGTGCATGCTTCTGGAGGAACCACGATGAAGTCCGGCTTCACCTGCGCGGCGTCAGTCTGCGACGGCGGTGCAGTGGTCGCTTGGGGCCGGGCCGTGGGAGGAGCATACGGCTCGCACACGATCGGGTCCGCCTCTTTGCCGCCGGCACGCCCACCACCAGTGCCACCTCCAGAAACTCCGCCACCGGAACCCCCACCACCAGTTTCACCGCCGCCTGAGCCTCCACCATCAGTGCCACCCCCACCGGTTTCACCGCCACTACCAGTGGACGGCGTCGTCGACTCTGTGGACGGAGCAGTCGTTTGATTGGGCGCAACCGTTCCGCTTCCCGTAGCGCCACCCGCGGTCCCAACTGGGGTTGGGCGGGTAGTCAAGTCCGGTACGTGAGGACCACAAGCAGTCAGGGCAAACGCGATGAGCAGAACTAACGCAAATGGCCTACGCATTCCGTAAACTCTCATGTGCTCACAATCCGCTCCGACCGAAGCCCAGTCGTCTGGGGGTCTACTGGGGCGGTCCTTTCGTCAGACCGCAGCCAGTTGGCATCCATCGTGCGTCGCTTGTCCCATGCATCCGTGCCCAAAGAGGCAATAAATCGGGCAGCTTTACCGCCTCGTATACGATGGGGCGGCGCCTACTCAGGCTTCTTCGCCCGGCTGGGCTGAACGCGGGGCGGCTCGCCCGGCATCTTTGGGTAGTCGGGCGGGAACGGCAGCTCCCCCAGCCCGTTGCCGATGTCGCGCTCCCACCACTCCAGGAGTGTATCGATCGTGCCCGGCTTCGCGTGCATGTCCGCCCACGGGTCCCCGATGGTTTTCAGCCGGTCCGGCACGGTGAGGATGGTAAAGTCCTTCGGCCTGACATCCGCCAGCTCATCCCAGGTGATGGGGCAGGACACGGACGCATGCGGAAGGGCCCGCGGGCTATAGGCGCCGGCGATGGTGCGGTCCCGGTTGGCCTGATTGAAGTCGACGAAGATACGTTCACCGCGTTCCTCCTTCCACCAGTTCGTGGTGACCCTGTCGGGCATGCGGCGCTCAAGCTCCCTGGCGGCAGCGATCACGGCGTGGCGGACGTCGAGGAATTCGCGGGTCGGTTCAATGGGGGCGTAGACGTGCAGGCCCCGGTTGCCCGAGGTCTTCAGGAAGGCGTCCAGCCCTGCCTCTGCGAGCACCTTCCGCAGTTCCAGGGCCGCGGGGATGGCGTCGTCGTAGTCGGTGCCGGGCTGGGGGTCCAGGTCGATGCGCAGCTGGTCGGGGTTGTCCGAGTTGACTGCATGGGACGGCCAGGGGTGAAAAACCACCGTGTTCATTTGCGCTGCCCACACCACGGCGGCCGGCTCGTCGAAGACCAGCATCGGGTGCGAGCGCGCGCTGGGAAAGACCACCTTCACCGTGCGGATAAAGTCGGGAGCGCCTTTGGGCGGGTTCTTCGAGAAAAACATCTCGCCGTCCACGTCGCCCGAAAAGCGCTGCAAAGCCACCGGCCGGTCGCCGTTTGCCCGGATGAAGGCCTCCCCGACATCCACGAAGTAGCGCGCCAGGTCCAGCTTGGTCAGCCCGAGCTCGGGCCACAGCACCCGACTGGGACTTGAGATGCGCATTTCCCTTGGGCCGTTGGGCCCGTCGACACTGAGGGTGGTCTGTTCACTGGCCATGGGGACAACCTACCCCGCCCGGCGGGCGGCGTCAGCAGTTTCCCATTCACGGCTCCTGCTGAGCAGCCCCTGCCAAGACGGGTTCCGCCGTCGGACATCGCCAAAACATCCAGCCGCTCTATGGGCAGCAGCGGGACCATCTGTAAGGATGAAAGCCACGGGCGCCGCCAGGCGCAGAGCATCCTCGAAGGAGACCCATTCCATGGTTGAATCCGCCAGTCTGGACGCTACCCAAGGACCTTCCGACGCCCGGGAACCGGGTGAACAGCAGCTGTTCCGGACGACGGCCGCGGAGGCCGGCCTGGTTCCCGGCAGCAGGGACTGGAACGCGCTTGAGGAACGCTACGACCGGCACTTTCCCGACCTGTCCAGGCTGTTCCGTTCGCTGTACGGATCGCGTCCGGACGTTGAGGAACAGCTGGCCGCCCTGGTGGCGGAGATGGCCCGCTCCTGGCAGGACCGGCCCGCCGACCTGAAACAGCTCGACGACGGCCGGGAAGACAACAGCGACTGGTTCCAGTCCAACCGCATGCTCGGCGGCGTCTGCTATGTGGACCGCTACGCAGCCGACCTGGAAGGTGTGCGTGCCCGCATCCCCTATTTCAAGGAACTCGGCCTCACCTACCTCCACCTGATGCCGCTGTTCCTTGCCCCGGAACCGCTGTCCGACGGCGGCTATGCGGTCTCCAGCTACCGGAAGGTCAATCCGAAGCTTGGCACGATGGACCAGTTGCGCGCCCTCGCCGCGGAATTGCGCGCCAACGGGATCAGCCTGGTGGTCGACTTCATCTTCAACCACACCTCGAACGAGCACGAGTGGGCGCAGCGGGCCGCCGCGGGCGAGCCCCGCTACAGCGACTACTACTGGATCTTCCCGGACCGCACTATGCCTGACGCGTTCGAACAGAACGTCCGCGAAATCTTCCCCGAAGACCACCCCGGCTCCTTCGTGCAGCTGCCGGACGGCCGGTGGGTGTGGGCCACGTTCCACACTTTCCAGTGGGACCTGAACTACTCCAACCCGGAGGTGTTCCGGGCCATGGCCGGCGAGATGCTGTTCCTGGCCAACCTCGGCGTGGACATCCTTCGCATGGACGCGGTGGCCTTCATCTGGAAGCAGCTGGGCACGCCGTGCGAGAGCCTGCCCGAGGCGCACACTCTGCTGCAGGCCTTCAACGCCGTCTGCCGGCTTGCGGCGCCGTCGCTGCTATTCAAGTCCGAGGCGATCGTGCACCCGGACGAGGTGGCCCTGTACATTGACCCGGCTGAGTGCCAGCTTTCCTACAACCCGCTGCAGATGGCGCTGACCTGGGAGGCGCTGGCCACGCGGAACGTGTCGCTGCTGGCCCAGGCCCTCGAACGGCGGCACAACATTGCTCCCGGGACTTCCTGGGTGAACTACGTGCGGAGCCACGACGACATCGGCTGGACGTTTGCGGACGAGGACGCCGCCGAGTTCGGCATCAACGGCTTCGACCACCGCCGGTTCCTGAACTCGTTCTACGTCAACCGGTTCCCCGGCAGCTTCGCCCATGGCGTGCCGTTTCAGGACAACCCGCGCACCGGTGACTGCCGCATCTCCGGCACCACGGGGTCGCTGTGCGGCCTGGAGGAGGGTTCGGCGGAGGCGATCCGCCGCGTACTGCTGACACACTCGGTGGCCTTCAGCACCGGCGGCATCCCGCTGCTCTATCTCGGTGACGAGGTGGGTCAGCTCAATGACTACGGCTATGCCCAGGAGGACGGCCACGAGGCGGACAGCCGGTGGGTGCACCGACCGCAGTTCCCCGCGGAAAAGTACGCCAAACGCCTGGATCCCGCTACTCCTGAGGGGGCTGTGTATGCGGGGCTGCGTCGGCTGATTGAGGTCCGTGCCGCGACTCCAGAACTGGGCGGCACACGCCTCGTTCCCTTCACCACGAACAATCACGCCGTCCTGGGCTACCAGCGCCCCGGCGTGGGAACCGCAGTACTGGCCCTGGCCAACTTCAGCGATGGCCCGCAGGTGGTGTCGGCCGAGACGCTATCCGGGTTCGCGGCCGAAGCGCTGGACCTGTTTTCCGATGTGCCGGTCCGGATCGACGAGGGGCTCGTGCTGCGGCCGCAGGACTACGCCTGGCTCCGGGTGGTCCCGGCCGACTGAAGCGATCGGGCATGATGAACTCATGCCCACAGCTGATACTCCCGTCACCATTGCCGTCGGTGACGGCCACGTGTCCGGTGCCTACGCACGGCCGGCCAATCCGTTCGCAACCCTGGTGCTTGCCCACGGGGCCGGGGCGGGCATGGAACATCCGTTCATGCGCGGCTTCACTGGCGCCTTGAACGACGACGGCGTGGCCACCTTGCGCTTCAACTTCCCCTACCGCGAGGCGGGCCGGAAGTTCCCCGACCGTCCGCCGGCAGCCATTGCCACCTGGCGGGCGGCGATGGCTGACGCTGCAGCCCGGTCCGCAGGGAAAAGCGAGCCGGTGTGGGCTGCCGGGAAGTCGTTCGGCGGCCGCATGGCCTCCATGGCGGTGGCCGAGGGCATGCCTGCCGCAGGCCTCGTCTACCTCGGCTACCCGCTGCACCCGCCGGGCAAGCCGGAAAAGCTCCGCGACGAGCATCTCTATGGGCTAACAACGCCCATGCTCTTCCTCCAGGGGACACGCGACACTTTCGCCACCCGGGAACTGCTGGAAGGCGTGGTTTCACGGATCGGACCTACCGCCACGCTGCAGTGGTGCGAGGGCGGCGACCATTCATTCGCTGTTGCCGGCAACAAGCGAAGCGCCGAAGAGATCGGCGCCTCGCTCGCGGCGCCGGTCGCCGCATATATTCGGGCCAACAACCCTGCCGGCCACTAAGTCGCACGGTCTGGGCACAATTGAATGCCCAATAGGGCAGCCCATCGGAGCCCCGCGACTCCCATGCTTCAATTCTTCCCCGCTCACTAGGGAAATTGCTGCTGTTCCAGCACTCAACGTGGATCTAAAGGGCAAAGCTCGGACACAGGAGCAGTGACTGCGGGTTTCCCTGTCAACGAGGTGAAGCCACAATGAGGTCCATGCCTGCCGCGTGCCCAGTTCGGCGGGTCAAACTCGGGAGCATTTGTGGCAGCTCGAAGTACGCGACATACAAACAAGGAACGGCCCTCCGCCAAGAGGAATATCGTTGGCAGCCTGACATTGCGAACTCTTGCGGCAGCACTGATCCTAGGTTTTGCCGTCTTCGCCTTCAGCCAAGGCCCAATCAGGAACAATCGCCATTCTGCTGGCGAGGTCGAATTGCCAATGGCTCCGACCGGCAGCGAAGACGCACCACTCCTGGACCCCAACAACACCCCGCGAGTGAAAGTGCCTTTTCGCCCGGTAATCTCCAATGCTGCCCTCAAGGGAGCCTCGACGCCGGGCGTTGCATCAGCACTACTAAAAAGACCCCCGCGCGGCTCCCTTATGGCTCCTCTTGAATTCTTGGTCAAAACTTCTCAGTTCGGGTCGCGTAGAAATCCAATCACGGGGCAATTGGGTGAGTTCCACTATGGGCAGGATTTCGGTGCAGCCTGTGGAACGCGGGTATACGCTGCCGACGCAGGCGTGGTCCGCGCAGCGGGTTGGCACCCTTGGGGAGGGGGCAACAGATTAGAGATTGACCATGGCAACGGCCTGATTACGACCTATAACCATCTGCTGAAGTTAGGTGCCGAAAAGGGCAGCAAGATCAGAGTCGGCGAGGTTGTTGCCAAAGTGGGCACTTCAGGATCATCGACCGGCTGCCACCTGCACTTTGAAGTCATCGAAAACGGACAGCATAAGGACCCTAATCGGTGGACGTTACTGGGCATCCGTCAGATTGACCGCTTAGCCCTGGACGATAGGATGATCAGCTTTGATCCGAGTTCAGTAAAGACGCTGACCTGGACGATTCCCACCATAGCTGGAAAGACCTTCAGTACGAAGGAGCCTGCTCCACCACCTCAACCGCCGCATTGCAGCACCAAACCGCTGCCTTCGGACTGCCCTGCGCCAGACAAGTGCAGGTTCGACCCGCAGGCACCCGGCTGCACACCCACAGACAAGTGCAAGACCAACCCACAAGCACCCGGCTGCACACCCACAGACAAGTGCAAGACCAACCCACAAGCACCCGGCTGCACACCCACAGACAAGTGCAAGACCAACCCACAAGCACCCGGCTGCACACCCACAGACACGTGCAAGACCAACCCACAAGCACCCGGCTGCACACCATCGCCAGAGTGCACGGTCACGGCCGGCATTCCGATGGCGCCGGGATGCGCCCTCCCACCGGGCTGCGCGGTCCAAGCCGACGGAACCATGCCGGCTAACTGCCCGCTCCCGGCAGGCTGTGGTGTCAAAGCCGGGGTTGCCATGTCTGCAAACTGCCCTCTCCCGGCAGGATGTGTCGTCCAAGCCGACGGGACTATGCCCGCCAACTGCCCCCTTCCCGCGGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAATTGCCCCCTCCCGGCAGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAACTGCCCCCTCCCGGCAGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAACTGCCCCCTTCCCGCGGGCTGCGTAGTCCAGGCCGACGGGACTATGCCCGCCAATTGCCCCCTCCCGGCAGGCTGCGTCGTCCAGGCCGACGGGACTATGCCCGCCAATTGCCCCCTCCCGGCAGGCTGCACCGCCCAGGCAGGGGTCGCCATGCCGAACGGATGCCCACTCCCGGCAGGCTGCGTCGTCCAGGCAGACGGGACCATGCCCGCCAACTGCCCCCTCCCGGCAGGCTGCACCGTCCAGGCAGGGGTCGCCATGCCGAACGGATGCCCACTCCCAGCAGGCTGCGTCATTCAAGCAGACGGCACCATGCCTCCCAACTGCCCCCTCCCCGCAGGCTGCGCCTACCAGTCCAACCAGCCTGTCACGCCGAACTGCCCCCTCCCGGCAGCCTGTGCCACTCAGGCGAACACGCCAGTCCCCGACGGATGCCCCCTTCCGGCCAATTGCGCCTACCAAGCCGGAGTAGCCATGCCGGCCAACTGTCCCCTCCCCACAGGATGCGGGGTTCAGCCACAATTGCCAGCCACGTGTCCGCTGCCGCTTGAGTGCCAACTACCGCCGGAGCAGTTGCCGGCCTGGTGTTCTCAGCCACCTGCGCCGGGCCAAGAGCTTGAGCCTTCGGCATCTCACCCGTCCTGGACGAAATCAGCCGCCGGCGAGTCACCAAAGTTCCAGGAGCTGCTGAACTAAGGCTGGTTCTGCACCATGGGCGTCTGCCCTGCAATCAGGCGTTCGCCGCCGCAGGCGCCACGTTGCCCGGGACGGGTTCGTGCCGCAGGTAACTGCGGCGGAAGCGGCCGGTGCCGGCAGTCAGCGCCCGCAGCTGGACCGCGTACCGCAGGAGCTCCCCGTCCGGGACCTCGGCGGTGACTTCCGTGACGTCGCCGCCGGACGACGTCGTACCCGTGAGCCGGCCACGGCGGGCCGACAGGTCGCTCATGACAGACCCCACGTACTCGTCGGGGATGCTGATGGTGACAGAAGAGACTGGCTCCAGCAGCTGGATCCGCCCGGCGGCCGCGGCCTCCCGCAGCGCGAGTGCACCGGCGGACTGGAACGCCGCGTCGGAGGAGTCGACGCTGTGCGCCTTGCCGCCCACCAGGGTCACCCGGATGTCCACCACCGGAAAGCCCGCCGACACGCCCTTCTGCATCTGGGCCCGCACGCCCTTCTCGACCGAGCCGATGAACTGGTTCGGCACCACCCCGCCCACGGTCTTGTCCACGAACTCGAAGCCGGCCCCGCGTTCCAACGCCTCCACCTCGATGTCGCAGATCGCGTACTGGCCGTGGCCGCCCGACTGCTTGACGTAGCGCCCGTGTCCGGCCGCGGGGGCGGCGAACGTTTCCCGCAGCGGCGTCACCACCGGCACGGTCTGCAGCTTCACGCCCTGGTCACGCAGCCGGTCCAGGACCACCTCGCCGTGGGCCTCACCCATGCACCACAGGATCAGCTGGTGGGTTTCCGAATTGCGCTCCACCCTTAGGGTCGGGTCTCCGGCGGCCACCTTGCCCAGGCTCTTGGCGAGGGCATCCTCATCACTGCGGGTGGCGGCCTCGACGGCGAGCGGCATCAGCGGCTCGGGCATGTCCCACGCGGTGATCAGCAGCGGGGCATCCTTCGCTGACACGGTATCGCCGGTCTCCGCGCTGCCAATCTTGGTGATGGCGCAGATGTCCCCTGCCACGCAGTACGGGATGGGCCGCAGGTTCGCCCCCAGCGGCGAATACAGGTGGGCCAGCCGCTCGTCACTGTCGTGGTCCTCATGGCCGCGTTCGGCCAGCCCGCGGCCGCTCACGTGCACTGCCGAATCCTCGCGCAGCGTGCCGGAGAAGACGCGCACCAGGCACACCCGTCCCAGGAACGGGTCGATGGTGGTGCGCACCACCTCACCCGCCAGAGGTCCGTCCGGGTCGCACGTCAGCGGCCCCGCAGGCTCGCCGGCAAGATCGGTCACGTCCGGCACGGCACGCTCCAGAGGCGTGGGAAATGCCCGGGTCAGCATCTCCAGCAGTTCCGTCATGCCGAGGCCGGTCTCGGCCGATGCCGCCAGAACAGGGAAGAACGATCCCCGTGCCACAGCTTTTTCGAGGTCCCCCACCAGGACATCGGCGTCGATATCCTCACCGCCGAGGTAGCGATCCATCAGGGACTCATCCTCGCTCTCGGAGATGATCCCCTCGATCAGCGTGCCGCGTTCGGACTCGGCAGCGGCACGCTCATCGGCACTGGCGTCCCGGACGGCGGGCTCCGGGGATTCGCCGTCGTACTCCGACACCTGGCCGGACAGCAGGCCGAGCAGCCCCGTGACACTCCCGTCCGTTCGCACCGGGAGGTAGGCAGGCACCACGGACTGCCCGAACGCGCGCTGGCAGGCGGCCAGGGCGGCCTCGAAATTTGCCCGTGGATGATCAAGCCGCGTGATCACCACGGCCCGCGGTGTGTCCAGCTGGGCGCACTCCGCCCAGAGCGCGGTGGTGGCGGCATCGACGCCGTCCACGGCCGACACCACGAACAGCGCCGCGTCCGCAGCGCGCAGCCCGGCCCGCAGCTCGCCGGTGAAGTCCCCATAACCGGGCGTGTCCAGCAGGTTCACCTTCACGCCGTCGTAAACCAGCGGCGCCACGGAAAGCACCACGGAGCGCTGCTGGTGGATCTCCGACGGCTCCGCATCGCTGACCGTGTTGCCGTCAACGATCGAGCCCATCCGTGGAATTGTCCCGGCGGCGGCGAGCAGGGCCTCGAGCAGCATGGTTTTGCCGGCTCCGGAGTGTCCCACCAGTGCGACATTGCGGATGCCCTCCGGCTTGTCCACCGGCGCTCCGGCGGACGCGTCCGCCCGCCGGAGATCGGAGCTGCCGCGGCCCGGACCCTTGCCCCGGCCGTTAGTGCCTTTTACCGACATGACCATCTCCCGGCGTGCTAGTCGTGAGCCGCCAAGCGGCCTTAGTAAGACGATTCGACACCTAAAGCTGCTGTTCAGCAAGGGGTCAGGGCCCCTCAGCAGGAGTCCGACGGCGCGGCGGCGCGGCTCTCCGCGCCAGCCCACCGAAAGCGAATAACCCGTTGCGGTGCCATCCCGGTAGGGGCACGATGGATAACGTGGCCGCACGGGCCGGCCCATGCCAACCGACCAGTCGCCAGGGAGCAGTCGATGAGTGCGTGGAATGAAAATATCGGTGCAGGATCAGCCGGACTGACAGCGGTGACCGTGGTGGAGGGCTCCTCCTTCTGCATCTCCGCCGAGAGTGGGGACGTGTTTCCCGGCCAGCCGCAGGGTGCGTTTTACCAGGACACCCGGATTCTGTCCCGCTGGCAGCTGACGGTCGACGGCGTTCCGCTGGAGCCGCTGTCCGGCCAGACCCGCGAACCGTACCGGGCTGTGTTCATCGGCAGGCCGCGCGGAGCCAGCGGCGCTGTGGAGAGCCCGCTGGTGGTGGAGCACAACCGGACGGTCGGGCCCGGGCTTCGGGACGACATCAAGGTCCACAACTACTCCGAAAAGCCGCTGACCTGCCGGATCCAAATCAGGGTGGATGCGGACCTGAGCGACCTGTTCGACGTCAAGGGCGGAAAGGTCGTCCCGTCCGCCGAGCACAGCCGGAAGGTCCGGGCCGAGGCCCTGCAGATTGACGCCATACGCAACGGAATCCACCGCGGCGTGGTGATCAGCGCCCAGGGTGCCATGGTCACCGAGGATGCCCTGACGTTCGACGCCGACCTGGCCGCCCGGGGCACCTGGACCGCCAGCGTGTTCACCACTCCCCTGGTGGACGGCGCCTTCCCTGAGCAGCCATTCACCCACGAGACTGCCCCGCACGTGGGCGCGCAACGCTACGCCGCCTGGGAGGAGCATGTTCCCCGGCTCACCGTAACTGACAAGAACGTGGAAAAAGTCCTCACCCGGAGCCAGGAGGACCTGGGTGCCCTCCGGATCTTCGACCCGGAGCATCCCGAGCGGGCCGCCGTCGCCGCCGGTGCCCCGTGGTTCATGGCGCTGTTCGGCAGGGACTCGATCCTGTCCTCCTACATGGCCCTGGCGGTGGATCCGAAGCTGGCCACAGGAACCCTGCAGACCCTGGCAGCATTGCAGGGCAAAAAAGTGGATCCGGACACCGAGGAGGAACCGGGCAGGATCCTGCACGAGGTGCGGCTGGGCGTCACCGCCGGGCTGGCCCTCGGCGGCAGCCAGGCGTACTACGGCACAGCCGATGCAACTCCGCTGTTCGTGGCACTGCTGGCGGAGCTGGGACGCTGGGGCCTGGCGGGCGACCTGCTGGACTCGCTGCTGCCGCACGCCGACCGGGCCCTGGACTGGATAGAGAACTACGGCGACCGGGACGGCGACGGCTTCGTGGAGTACCAGCGCGCCAACGAACACGGACTGCTGAACCAGGGCTGGAAAGACTCCTGGGACGGCATCAACTTCGCCGACGGAAGCATGGCGGAGGCCCCAATAGCGCTGTGCGAGGTGCAGGGCTACGTCTACGGCGCCTACCTCGGACGGGCACTGCTCGCCCAGCAGCTGGGCGATACGGACATGGCGTCAAAGTGGAACCGCAAGGCCGCTGACATCAAGGCCGAGTTCAACGACAGATTCTGGCTCCCCAAAAAGGGGTACTTTGCCGTGGCCCTGGACAAGGACAAGCGTCCGGTGGATGCCTGCGCGTCCAACATGGGCCACTGCCTGTGGTCAGCCATCGTCGACGCGGACAAGGCGCCCCTCGTGGCGGAGCGGCTCATGTCGCCGGAGATGTTCACCGGCTGGGGTATCCGTACTCTCGCCTCCGACATGGGCGCCTACAACCCCGTCAGCTACCACAACGGTTCGGTGTGGCCGCACGACACAGCCCTCATAGCCGGCGGACTGATGCGGTACGGGTTTGTCGAGGAGGCCACGCGCATTGCCATGGGCCTGTTTGATGCGGCGGAAAAGTTCGACGGGCGGCTGCCGGAACTTTTCTGCGGGTTCTCGCGGGACGATTTCCCCGACCCCGTCCCCTTCCCCACGTCCTGCTCGCCGCAGGCCTGGGCCTCGGCCGCGCCGGTGCACCTGATGCGGATCCTGCTGCGCTTCGATCCGCTGCTTCCCCGCGAGGAGGTCTGCCTGGCCCCCGTGCTTCCGGCTGCGTTCGGCAGCTTCCGGGCGGACCACGTACAGATGGACTCGGCCCGTATCACCGTCCAAGCCACCGGCACCGAAGGGTCAATCGATGGCCTGCGCCAGGGCCTGACCTTGCTGCACGAGCCCCGTCCGCCGCTGGCACGGCTGATGAGGCACTAGCCAGGGCACCGGTCCCACCCATAACTGAATGGTCTCAGTAGTTAAAACGGTCTCAGAACATCCGGACAACAAGGGAGCTGCGGATGCGTATCGTTTTAATTGCGGGGCCTTGGTATCCGATTCCCCCCACCGGGTACGGAGGCATCGAACTGGTGGTCGACGCCCTTGCCAGGGGATTTTCCAGGGCCGGCCATGAGGTTCTGCTCGCATGCGCGGCGGACAGCACCTGCCCTGTGCCGCAGCTCCCCGGCATGCGCCCCTCCGAACCTGACTTCGTGGGGTTCACCTCCTCCGAACTCAGCCACGTCGTCAACGCGTATGCCGGGATGGACGGCATGGTTGACCTGGTCCACGACCACACCCTCGCCGGCCCGCTCTACCGCGGGCGTCCCGAGGGGCTGCCGGTGGTGACCACGCTCCACAGCGACCTGAACCCCTCCTTTACCGCCGTTTATGGCGCAGCCGCCCGGGACACAACCCTGATCGCCATTTCCAGGAGCCAGGTCAGCAGCGCGCTGGCCGACCGGGTCGCGGCAATCATCCCGCACGGCATGGAACTGTCAGCCGTTCCGGTGGGTCAGGGGCAGGGCGGCTATGCGTGTTTCCTCGGGCGGATGTGCCCGGACAAGGGCGTGGTGGAGGCCATCGAAGTGGCCCGGCTGGCAGGGATTCCGCTTCGCATCGCGGCGAAGATGCGGGAACCGGCTGAGGTGCAGTACTTCCACGACGTCGTGGAGCCGATGCTGCGGCCGGACGTGGAATTCCTCGGCGAAGTGGGCGGCGCGGACAAGTACAAGCTGCTGGGTGAAGCCGTCGCCCTGCTCAACCCGATCCAATGGATGGAGCCGTTCGGCCTGGTGATGATTGAGGCGATGGCCACCGGCACTCCGGTCGTCGCCACCCCAATAGGGTCAGCCCCCGAGGTCATAGACGACGGCGTCACCGGTTATCTGGCCTCGGCCCCAGAGGAACTGGCGCGTCTCCTGCTGCGCGCGCCGGACCTGGACCGGGCGACAGTCCGGGCTCAGGCCGAGGACCGCTTCAGCACCGAGCGCATGGTCGAGGACCATTTGGCCCTCTACACCCGGCTGATCGGGGTCACTTCAGCACGGTAACCATTTCCGGGAGCTAATTACTTTCGGGCGTTGGTCCGTGCGGTAGCCGTCGCGGTCCAGGGGTCCTCTGGCCACGGGTGTTTGGGATAACGGCCACGCATCTCGGCGCGGACCTGTGCATACGGCCCTGACCAGAACGAGGCGAGGTCGTCCGTGACGGCCAGCGGCCGCCTGGCCGGTGACAGCAGGTGAAACTGCACCGCCACCTTTCCATCCGCCAGCCGCGGTGTCCTGTCCCAGCCGAAGCATTCCTGGAGTTTGACTGCGACCACCGGCCTGCCGCCGTCGTCCTCTGCCTGCGGGTAATCAATCCTGACGCGGGAACCGCTGGGCACCTCCAGGAACTCCGGGGCGAGCTCACCCAACCGGGCGGCGTCGGGCCAGGGAAGCAGTCGTCGAATCGGGTCCGCCAGGTCGATGCCGGAGGTTGACACCCCTCCGGCCAGCGCCTCGAGCTCGGGACCAAGCCAATCGTCGAGCCGTGCCAGCAACGCCTGCTCGGACATGTCAGGCCACGGATCACCCAGCTCCCGGTGCAGCAGAGCGAGACGGCGTCGCAGTCCATCGGCCGACGTCGACCATCCGATAACTCCGAGTCCCTGCTCCTCCACTGCCCGGGCGACGGCGGCGTGGCCATCCGCCGCGGATGCCGGCACCGGCGTGGAGGACAGGACGATGGCGCCCAGCCGACGCTCCCTGCGGGCCGTCACCTTCCCTTGACTGAAGGCCGCCTCCACCGAGTCGCGCAGCAGGTGCGCTGCGGCGGCCTCGGCCGCGTCCGCCGTGAGCGGTGCGGCGGAGCGGATGACCGCGCCGGTCCCGGCGGCGTCCCGCCCGTCCGCCCGGGCAACTTCGGCGACGGCCAGCCATTCGTGTCCGGCCAGAGGGCTGCCGGCGGGCAGCCCGGCCCGGGTACCGGAGGTCAGCAGGTAGCGTTCCGGCCCATCTCCGGGCACGCGGCGTGCCACCCGGCCCGGGAAGGCGAGAGCCACAACCATGCCGACCTGTTCGGCACTTCCTGCCGGCAGTTCCACGGAGGGAACCTCCACCAAAGGAAGCCCGACGCCGGTCGCTGCCTGGCGTGCAAGCGTGTCCAGCCGCCGGGCCTCCTCAGCCCAGCGCCTGGCGGCGGGATCCTTGCCGGAGCGTAGCGTCGACACCAGGCGGGGAAGGTCGGCTCCGTTGGCGCGCTGGTCACCTGCCACGGCGGCAACCACCTCGGCTGCCGTTCCAAAACCAGCATGTGCGGGGGACGCCGAACCGCTGCCAGCCTGCCGTTCCTCGAGCAGCGCCGACCCCACCAGCAGGGCGCGTCCCAACCGGGGATCGGCGGGTATGCGTGCCAGTGCCTTGCCCAGCTCCATGGCGTGGCCGTCGTCCCCCACCGCGCCAAGCTCGCGCAGCACTTCAGTGGCGTCCGCCATCGCCAGCGGGGGCGGCGTGTCCGGCAGGGCAAGCCCGCGTCCGCCCGGTGCGCCCCAGCATGCCAGGATCAGGGCCGCTCCGGTGAGGTCGGACACTGCGATCTCGGGAGTCTGGTGTGCAGGTGCCGCCCCGAGTGTCTTCTGGTCGTAGCAGCGGACCACCTTCCCCGGACCCTGCCGTGCCGCCCGTCCGGCTCGCTGTTCCGCGGAGGCCCGGGAACAGGAGACGGTGACGAGGCCCGTCATGCCCCTGCCGGCATCGCGGCGCGGTTCGCGGGACAGCCCGGAGTCGACCACCAGCCGGACCCCGGGCACGGTCAGGGACGATTCGGCCAGCGCTGTGGATACGATGATCCGTGACGGCTCCCCCGGTTGGCGGCCGGACACGGCACGGTCCTGGGCGGCTGGGCTGGCTTGTCCATGGAGTTCCAGGATTTCAACGCCGGGACCCACCCGGGTGCGCAGCTGACCAGCCACGTGTGACACTTCCCAAACACCCGGCAGGAACACCAGGGCGTCAGTGCCGGGATCGGCGGCGAGAGCTTCGGCGTGCGACGCCGCGGCGGTGTCCGCCACGTGGTCAAGGAAGGCGCGCGTCACGCCGCGCCCGTCCAGGCGCGCCGCGGGAGCGGGCGCCCACGCCGTCTCCAGCGGGTGAAGCGCAGAAGGGCAGTCGACGACGGGAGCCGGCCCGCCGCCGTCGGCCTCCCCGCCGTGCTCTCCGCCCATGTTCCCGTCCTCGTTCCCTTCCTCGTTCCCACCGAGCAGGGCGGCGAACCGCGGCGCGTCCAGGGTCGCCGACATGGCGACGACCATGAGGTCACCACGCAGCTGGCGCACCTCGGCGAGCAGGCCCACCAGCAGGTCGGTTTCCAGGCCGCGTTCGTGCACTTCATCGAGGATTACGGCAGCGGTACCCTCCAGGCCAGGGTCGGCCAGCAGGCGCCGCAGCAGAATTCCCGGCGTCACAAATTCGATGAGGGTGGCGGGGCCGGCCTGCCGTTCGCCGCGGACGGTGTAGCCCACCCTGTCCCCCAGCTTCGTTCCGTCCAGGGCCGCCAGCCGCCGCGCAGCCGAACGCGCCGCAACGCGGCGCGGCTGGGTGACCACGATGCGCGGTTGCCCCTCCGCTGTGGAACCCTGCGCAAGGTTGGCAACCAGCGGAGGCACCAAAGTTGTTTTTCCGGTGCCCGGCGGTGCCTGGACCACAGCTGCTCCGCCGGCGCCCTGCTTTTGGAGCACGCCGGCCAGCTCTCCCAGCGACTCCGCAAAGACCAGCCCGGAGCCGATGGAGTCCAGGTTGAAGGGGGCGGAGGATGCCAGAGGGAGCGCGGAAGTCACCCTTCCATTGTGCCGGTCGGCAGCGGTGGGACCTGACGAAGACAGGCATGGACAGGAGCAGGCAGTCTAATGGCGGCCGCACTTCCGCCGGCAGTGACTTCTCTACGCAGCTGTGACTGATGACCAGTTGGGCCAAGGGTCCAAGGGCAGGGGTGGCTCAGGGTCGTCCCGCTCATCGATCTCGTCGAAATCCTGGGGATCGTGTGGCTGGTCCGGAGGATCAGGCCAGTCGGACGGTTCCGGCTCGGCGTGGCCGGATGGCGCGCCGAACCAGTCGGGTGGTTCCGGCAAGGCGCGGCCTGGTGGCAGTTCCGGGCAGTCTTGGCTGGGGGACGCGTCGGACCAGCCCGGCTGAAAGTTGTCCGGCGCAAAGTTGTCCGGCGCAAAGTTGCCTGGCGCAAAGTTGTCTGGCCAGGTGGGTGGTTCCCAGTCCTGGTGTTCGGCGGGGTAATGGCGCCCGGATGGTGAGATCCAGCCGGGCGGGCTTTCCAGGGTGGCGCCGACCGGTCTCCACGCCGTGGCGTGTTTCAGTCTGTGGTGTTTGGGGCAGGGCTGGCCGAGATTGGTCACGCCGGTGCCGCCGCCGTCGGCCCAGGCGAGGATGTGGTCGGCGTCGTTGTCCAGGGAGTGGTTGGTGCAGTTGGGGAAGGTGCATTTGGCGTCGCGGAGGCGCAGCCATTGCCGCATCGGTTTGGTGAGCCGGTAGCTGGTGCGCCCGATCTCCAGCGGCGCCCCGTCGCGGGGGTCGGTCAGGACCCGGAAGAACGACGTTGCGCCGTTGGCGACAAGCCGGCGGGCCATGGAGGCCGGGATCGGCCCGTACCCGTCGAGCGTGGCGGGCTCGTCGGTATGGCCGAGCAGCGAGAACACCGGAACCGTGACCAGCACCTGCGCCTGCGGGGACGGCACCTCACCGGCCGTCATCTCACCGGCAGGGGCGGAGCCTCCGGGGAAGGAGCCTCCTTGGCCGGCACCAGCTGCCCCACCGGTAATCCCCGGGGCTGGACGGAGCAGCGAGGTGGAAAAGACGTCGGCCCGGAGCTGGGTGAGGGTGCGGATTTCGGTCGGCCCTTGAAGACCACGCGCTATGGCGGTGGTGCGGTTCCAGATCCCGGCGGCCTGGTCCGCGGGCAGGAACGCCGAGATCCAGGCCATGCCGTCCCGGTCCGGGGAGTACTCCAGCCGCCGGTCCTTCACGCTCCTGGAATGCCGGGTTTCAATACTGTCCGGGTGGTGCCGTTCCCGCCAATACCGGGCCTTCGCCCGGAACCTGCCCGGTGCCAGCTCCCCGGCAAAGCAGCCCCGCGCCGCGTTCGGAGCATCAGGATCCAGGAAGTGGGCCTCGAACGCTGCGGCCGCTTCAGGTGACAGCCCTTCGGTCTCATCGCACATGATCCGCGCGTGCTGCCACGAAATACGGCCCAGCTGCAGCGCGGCAAGTGTCATCGGCCGTTCCCTGGTCAGCATGTCCGATTCAACCAGCAGCCGTTCGGCAGCGCCTTCGCTAATGGTCAGCGCGCCGGCCACCTCCGCCCTCACGGCCATCTGCCGAACGGCCGCGTCCTGCGGGCTGCCAACCGGGACTGCCATCGCCGCGTCCGCCGTGACGTACCCGGCAGCAAGCTCCACCTTCACAGCCGCAAGCCGCGCCTCCATCCCGCCCACCACCCTCAGGCCGTCCAGGCATGCAGTCGCCTGCTCCCCAAGAGGATCAACCGGATCCGGCTGGAAATCCCCGCCGGCCGCACCCGGATCAGCAGCCCCCCTCAGCTCGGCCGCCAGCGCCAAAGCAGAGGCACCAAGAGCCTCCAACACCTCCGCAGCAGCCACGCTGTTATCCATACCCCCAGTATGAGAAGGGGCACTGACAAAAACGCCCGGCCGGAGGATCGGGCGGCCCCGGAAGCGCATAATGGCATGATCTACAGGCGACAATTGCGACGGCAGCCCACGCCAGCGGATCAAAGGGCAAGGCTGCCCAGGACAAGGAGGTCCGGATGCTGAGGCTTCCGCGCATCACGGTTGAGGTTCCCGTGCTTGGCGTCGGTGACCGGCCCGCGGACTATGAACAGCTGGCAGCGTACGCCGACGGGCTGCGCAAGCCGGAGGGCCTCCACATGACACTGCTTCACATCGGCATTCTCGACGACTTTGCCGCCGATGTTGTGGCCTGGACCAAGGGGGCCACAGATCCCGCCGCGGCCGCCGTCAAAACCGCCGACTGGCTCCGTGCGCTGCCCGTGCTGGAGGGGTTCACCGGAACGGCGGAGAGGCTTGTTCTGTTCGGCGGCGGCAGGGTATCCGGCCTCGATGTGGAGGTGCCACAGCACGTACGCGATTTTCAGGTCTCTCTCGTCGCAGCCCTCCGGGAACTGCTGGAGGACCTGCTGGTGGACAACCCCGACGACTTCATCCTCAGCTCCCCGGCTCTGGGTTACAGGTACCCGCGGTGGCACCCCCACGTGGCCATAGGCAAGCCGAAGTCGCGTGACCATTCTGGAGAGGGCCGGTCCGGAGAAGGCCGATCGCGGGAGCGGAGCGGCTCGTGGGAAATCCGTCCGCTGAAGGTGGAGTTCGGACCGTCGCAGATCAGGAACCGGCAGCTGCTGCCGGGCCCCGGCGACGGCGGCCATCAATAGCCGTTGCTCTCACCCCTCGGCGACCATCTTCTGAAGCGCCTCCGAAGGAACGAGGCCCATTTCCGCCATCAGGCGCGCTTTGTAGTTTTCGAAGGCACGAAGCGCCGCCACCCTGTTCCCCTGCAGCTGTTCGACTTCAACGACGACTCGTACAGCCTGCTCGTACAGCGGCTCCAGGTCCAGAGCCGCCTCAGATGCCTCCAGCGCCAGCCGGTACTCCGCACGCCCGAACAGCTCACCTGCCAGGCCGACCAGGGCGTGCAGGCGCGCACGACGAAACTCTGCCTGCTCGGCCATGACCCAGTCTTCGTACCACCCGGGCAGCAGATCAGCACGGCGCAGGTCGGAAAGGAATGCGGCGGCGTGGCCATCCCCGCACCCCAGGCCCGGCTGCAAAATCTCTTGGTGGAGGCGGTGAAGATCAACCTCCACTGTGTCGTTCAATGACAGCACTGCACCACCGTTGGCCAGCAAGCCCGGCACCTGCCGGGCGATGAGATGGACGCTCACCCGGAGGCTGTCCAGGGCTTTGGGCTCCGAGTGCGCCGGCCACAGAAGACCGACCAGATAGCTCCGGGACCGCGGTCCCTTCAGAGCCAAAGCCGTGATCAGCCGTTGCTGGCGCAGGGGGACGTGCAAGGCCTCGCCGCCCTGCCGAAGTTGCCACGATTGAAACAGGCTAAGTTGAAAACCACCAGCATCATCACCGGACATGCCCGCCCCCAAATCCTGCAGATTAGAGATCCGGGATAGATCTAGGAACGAGAATGCGCAGTCGCGCGGCCTCTGTCAATCATCATCAGGGGCCGCAGCAAGCATGACTGCCAGCTATTACTTTTCACGCCGTTCCGCCAGCTATAGGTACTTGGACGGGCGCGGCGCCATACTGGGACGACAATCGTTCAGTTGCAGGGGTTTCCTTGGCTTACTCAACATTGGGACAAGCGGCTGCATCACATCTGGGGCAAGCTGCCGGGAGAACGCGGGACCAGTCCGCCGCTGCGTCACGGCCCGGTCCGTTCGGTCCGGACCTGCCCCAGTCCGTGGCCGTGGCGCTCGCCCGCATGCGCCAGAACCCCGCTGATCCGGAGCTCCTCCACGACGTCGCGGCAGCCATCGATGCCGCTGCCGGCAAAGATCCGGATTTCCGTCAGGCCGTGGAGGAATTCGTCAGGGGGAGGCAACGCCCGCCACGAGTACAACTGCGGGTCCTCGGCCCGGACCAGACACCGGAGGCCTCGGGGCTCCAACCGGCGTTCGGGCGGACGCTGAGAATTGCGCTTGCGATGCGCGGAGGGGTCAGCCTCGCAGTCTGGATCGGCGGTTGCGTGGCCGAACTGGACATTCTCCGGCGCCTGCGGATCTGCATTCCGGATCGCGCCGACGCGCGGGACAGGCCGGATCTCACCGCGTTCTACTTCAGTGGCACCGAGGGACTCGCAGAAAATCCCGCAGCCGCCCACATTCTCCGTCGGGCCACGGCCTATTCGACGCTGCTCGCGGAGACCCGCTACGACAGGGTGGAAATCGACATCCTGGCAGGCGCCAGCGCCGGCGGGCTGAACTGCATCCTCTATTCGGTGGCACAGATGGTCGGGGCTGCACCCGACGAAGACATATTGGAGACCTGGCAACGTGACGGCGGACTCCAGGAGCTCATGCGGCCGCCCGGTCTCCGAAAGGTCAACTCCATCCTGCAAGGCGACGAGTACTTTTTCCCGGGAATCCTGCGCGCGCTGGAACGGATCCATGCCACCGACCGCCGTCACCAGGCCCTGATTCCAGAGCACCTCACGATTGACCTGTCGGCCACTATTCTGGACAGCGAGGTCTCACGAAACCCTGACGTGCAGGAGGGGCGGGGAAGCTTCCACTTTGAAGGTCGCCATGCGGCGTCGGCCGCATCCGGCAACGGCCCGGTCCTCGAAAACAGGATCCCGGTACGGAACGACTTCGCCGGTGGCAGCGGACCGGGCGCCGCGGGCACGGGCCGTGCGGCCGCGCTGCCTCCCGAAGTCTCCGCGGACCTGGCGCGGCTCGCCTATGCCGCGCGGTCGACGTCGTCGTTTCCCGGCGCCTTTGAACCGGCAACGATCTTTTCCATGGAAGGCCCTCAAACCCTGCAGCCTTCGCGGGGGAAACCCAACATGCGGCATGCCTTCGGATCACACCGGTCATCGTCCGACCTCCCTGGGGAAGCCGTCTTCCATGTGGTGGACGGCGGCGTGTTTGACAACATTCCCATAGGCAGGGCGCTGACCGCAGCAAGGGGCCGGGTGTCCCAGCGCCCGGCGCACAGGGCGCTTCTGTATCTTGACCCTGACAGCGTCGGAGATTCCTTGCCCACAAGCCGCAGCGAGAACCTGTCACGCTTCCTCAACGCCGTCGGGGCGTCCGCCCTGCGGCTAAAGCGCAGGGAGTCCCTTGACTCCGAGGTCAAGGAATACGTCGACTACGTGAACGCCTTATCTTTGAACCTCGGCCGGTCGGAAGCCCTGGCCGCCGTGCTGTCCGACCGGTGGTCCACGGAGATCGCCGTGGACAGGCGCCGGGCCTACGTCCGCTACCGTGCCTCGGCGGACGTGGATCTGCTCACCCAGGTGCTGACCAGGCCTGACGAGTGGCAGGTTGCCTCCACGGTCACCGACCGGCGCAACTTCCGTGCACTCGGCAGCGACGAGCTCAGCGGGCTGGATTCGAGGATCATCCAAAAGTACCGGGATATTTCCAGGCAGGACGAGGAGGGGACAGCATTCCGACTGCTCACAAGTGACGCCCAGGCGTTGCTCGATGCCGCACAATGCTCCTTCTCGTGGCTCCGGCGCATGGAATCGGAATCATTTCCGAAGGAGTTGACGGACAGCATCGCATCCTTCGATGCACTTCGCACCGGCATATACGGAGTGATCAACAGTGCCGTGATCTTGCGGGACCAAGCCATCTGGGCAGTCCTCGAAAAATCAACGGACTGCGCCGAAAGTGTTCGTCATGAAAACATCATGGCGGCATGGTTGTCTGCGGCGGAAACGAACCAGCCGAGCCGCATGCAATGTTGGGCTGCGTTGCAGTCGCATTTCGAAGTGCTGGTCCGCTACAGCGCAGACCTCACCGACAGGGCCGCGGACGCCGGCAGCCATCCGGAGCTGCGCGAATGGACGGAATCGCCCTGGCCCGACCTGACCCGGATCGCCCTCTTAAGTGCACCCGATTGCGGGTTCACAATCCACGACCTGGCCCCTTGCCTCGCCGCCGCCGGCATCCCGCCGGTGGTTGCGAGGATACGGTACTGGCGGATAGGGAGCGACGAACGGCCCGCCCATGCCTGCGATTACTCGTTGCTGAAAGACGGCGAGCGCCGAGGCGCGGTGGCATTCGCCCTCAAGAACCCAAGCCTGTCACCCTGTGACCTGAAGGACTTGCTAAACCCGGATGCCGCCAGCCTTTCCTCCCGTTTCAAGCTTGCTGGCAACACGATGGCCAATTTCAGCGGGTTCCTGTCCAGGGACTGGCGCGAAAACGACTGGTGGTGGGGACGCTTGGACGCAGCCGCCGGCATTTCGCGTTTTCTGGAAACGGTGGCCGTGGACCAGAACCCACGAATCCCGGAACTGGACGGGGACCAGGAATTATTCGACGAGTCCACGGCAGAAGCGCCCAGAGGTTCCCGGAACCGCGTCACCTGGCTCCAGGACCAGCTCACGGACCAATGGTTTGGCCTGCAGGCCGCAGCTCCCGAAGATCGGCGGAAGGCGCGGCAGTCCATCCGCGCCGGCGCCGATAGCCCGTCAGACCTTGGCGCCGCCTACCGGATGATGCTCATGTCGCGGGGGCTGCGCGTACTCTGGCGGGCGCGCCCGGACGGCAACCTTCCCACCGCCTTGGGCAGCTGGCTGCTCCATGTCCTGCTGGTTCCCTTGTTCGCGGTCCTGCCGGCGATCGTCCACCCGGCCCGGCTGGCGTTCATTCTGGGTTTTGGTGATGCTTCCCTCTGGGTTCTGGCACGTCCGGAGAACGCGGTCTTTGGCGCACAGCCGTTCCTTCTCTATCTGGGGCTGGTCCTGCCTGGCCTGATTTTCCTGGCACTCGCTTTCGTGGCGCTCGCCGATGGGCACCGCCGCTGGCGTCCCGTCCTTGAGGTCCTCTCCGGTGACCGGCTTTTAGCCACGGAGTACCGCAGTCACCAGCGTTCCGCGGCTCGAAAAGCCATGGCGGGTCCGGTGGCCGTCATCCTGCTGCTGGTGCCCCTGGGGCTGGCGGCCAGCCAGGCGAGGCAATTGATGGTGGTTGTCTGCCTGGTCTTCATGGGCATACTCACGGTCGCGACGCGGAAGTGGGCCATGTCGGTGCCGGCACCCGTGCACGGAAAGCATCCCGCACTGGACTGGGGACTGGCGTGCACCGGTCTCCTGCTGGCCGTTGCCGTGCCGCTCGTCACGGAACTGCTGCATTGGTCCGCGGCACGGAACTGGCAGTCCCTGGCGGTCCTGGCTTGCAGCCTGCTGGTTCTGGCCCTGGTGCTCACCTGTGACTGGCTGACTGCAGTGGGCACCCTGCTGACCGGCCTCGCCGCCTCGGCCGGCGGAATTCTTGCCGCTTGGGGCGTCTGGGTTCTGCTCGCTACCCTCCGCCAGTCCGAACGCACCATCCTCTGCCTTTTCGCCGCATTCGTGGCCTGGGGACTGGCGGTCTGGTGGATGCCCGAGATCACGCGGATGCTCAGGCACCGGTCGGATGCCGTGGTTACGGTCCCCCGACGCAAAGGCGCCGAGGTGTCACCACCGGATGTCCCCGGGCCGGTCCAGCGGGTCCCTGGCCTGCAGTGACTCCGGTGCCGTGAATGTGTCGGCGTTGCGCAGGTTTTCCGGGAATACCAACCGCGTACGCTCCTGAATTTCCCTGACAGCGACCTGAAATACCCGGAATTCATCAAGCTCCAGTGCTTCGAGCTGATTGAGGTTCTGGGTCAGCAGGAAGGCGCGTCCCTGCAACTGGCCATCCTCTACGAAGGCGACGATCTTCCAGTACTCCCTCGGCAAGGGGACACCCCGGTATATGCGGTCATTCGCCTGGAACACCGGACCGCCAAAGACGCTGACCCTCAGATCCTGGACGTCGACGTCGGCGAATACGGCGTCTTCAATGCGCCCCCACACCCCTTTTCTGGCGCTCTGGTTGAAGTCCTCCAATTGCGGCGTGATGTTGGTGAAGAAGAACGAGTCCTTGTTGGCCTGTTCTGCCTCCGTGAGATCGCCCCACAGCAGGTCTGCACGGCGCGCCAGGTGGCCCCGGTCCAGGCGGTTGTCGCTGTAAAGTTCATCCCCGCACTGGAACCTGCCCGGGATCCTCGGGTCCTTCGTGAAACTAAGCGACTTTCGTGGGATCCTCTTCAATGCCCCGCCGTCTATGTTCCAGCCGACCCACCGGGCGAACCGGCGGCCCGCACTCATGACAAGCGAGAAGTGGGTGTAGGGAATTATGTCCGAGCCGTCCAGCGGCACCGCGTCCCCCTGAAGCGAGGCATCGAGGGTTGGCGGGTCGAGCCGGACGCCCAGGAAGGAGGGGTCATAACCCACGGCCACCGCGTCGGCGATTGCCCCGGAATCCGGCCGCACCAGCGTAATTCCGAGTTTCTCGAAGACGGATTGCGGCAGGCAGGCAAGGGCGTGCTCGTCCACGCTGGTCCCGGTTTCTCCCGCGAAGTGCAGCCCCGCAAGGACATTTCCGGGGGTTCCGTCGGCGTTCTTGAAGAGCCAGGCCGCACCGGAGTCACCGCCCCGGCTGATCTCCCCGTCCTCCGGCAGGTTCTGCTCATCCAGGCCAATCTCAAAGCCGCCTATCGCCTGCTCACCCGCGGCCCCATAGTGCAGTTTCGCGATCACGTCGACACGGCGGACCACGCCATGCGTCAGGCCGGTGGTGCGGCCGCTCTTCAAGACCTTGTCGCCGATTTCCGGTTCTCCCAGTTCCCGCGGTGTGGCGCCGACACCGAGGATTTCCGGATTGACGGTACGGCCCTCGATCGTGGCTACCGCGCAATCCCCCGCCACACCGAGGTGCGAGCGCTTGAGAACCCCGAGCCGGTTCCGGTCGACTCTGTTGTCATCGTATGGTCCGGGCTGCACCACCACGTCCCCCAATGCCCCACAGGTCCCGTGCAGCACATGCCAGTTGCTCAGCACGAGCGGTTCACCGTCAGTCTTGTCGTAGACAATGCAACCGATCGTTCCTGCTGTGCCCTGATAATGGGCGACGCTGACCCCGGGCAGCACGGGGTCAACCCGCACCTTCGCGGCAGGCGGCTCGGCTTCGGCCACAATGCGGAAACCCGGCCGGTAGCTGCGCTCGATCACATCGGTGGGAACGGCTACCCCGTCGATGATGATCTCACCGGGAATCGGCACCGTACCGAGTGCCTCAAGCTCATCAGGTGCCGCTTTCCGGTCGACAGTGAACTGCAAGGCGAGCTCACCGGTTGGACTGCCCTCACTCATCTTGTACCCGACCCCGATGGAAGAGATATTGGGGTCTTTGAGATACTCCGCTCCCCGGGTCCTGATGAACTGCCGCAGCGACTTCCTGGTCTCTTCCTCCGCCCCGCTTTTCCTGCTGGCAGACTCCTGGCCGGTCATCGCCCCACTCCCTCACCTTTTCCCGAAAGGGCGTGCAGCAGTTCCAGCGCGCGGTCCCGGTACTCCCCGCCGGCCGCTTCTACTGTCTCCGGAGAACTTCCTGTACCATCCATGGCCGCCAGGGCTGCTTCGGCACGCTCCTGAAGGTCTCCCAGCCGTTCGGCAGCGTGCGGGTACAGCAGCGCCAGGCCCCGGCGGTCCCCGGCCGAGAGATCCTTGCCGTTCCCGGTGGGCGCGCAACTGCTCGGACTGGACTTGTAGAAAAAGTCAGGAAAGCTGTACAGCATCACCGAATCGGAGTCGAACGGCCCTGCAACCACAGCGGGATCCTCCACGGTTCGCAGATTGTGGTCCACCTTCGCCCGGGGCCAGTTGTTTGGCGGGCCTGCAAGGTAGGTGTAAATGCCGGGGCGGCGTCCGGCCGCGTCCGGAATGAAAACCCCTTTGGCGTTCGTGGTGGGCGCGTAGTCCTGATCGTCATCCCACCTGAACTCCGCCTCGCAGGAGCCCCGCATGTTCTGGTGGGAGTGGTGGAACGCCAGCGCATGCAGGAATTCGTGCCTGACGGTGCCTTCCCACCTTTCGGGCCGCTCCGTCGTGAATCCGCCAAGATTCAGGCTGCGCTGGTTCGGCCGTCCGCCCACCGGCCCTGCCGGAGGGCCGATGGTGCTGTCGGTGCTGTCGGTGCCGACCAGGGAAAAGTAGCCGCCCATGTTGAACCCGACCCGGATCTCCGCCGCATGGAAAGTGTCGTTCTCGTGCCAGCGCCGGTAGTTTCCGGCGGCGTCCACGCCGAAGTCCAGTTCCAGGTTGCAGGCGTCACTAATCTGCCTGGTGGCCCCTGCCACATCTGCATGGAGTGCGGTGTCTCCGTCAAGGAAAGCTACCCGCACGGCGGAGCCTGGTTGCCAGCGGGCCAGGTCGGAGACGAGAAATTCCAGGGCAGTGTCGCTGCCCGCCATCTGGCTCCGCCATGCGTTCCGGTCCGCGATGGAGGCAAGTACCTCGTCGGGAAGTGATTCAAGTTCCATGGCCAACCTTCCACTGCACTGCTTCCAGCCGCTCCCGGGGACGTGACGGGTGGGCACGCACAGGAGCAGGACAATAACTTAGGCCCGCAACCATTACTGCAGCGTTACAGTCCTGCCGGCGGCAGCCGCAGACACCCCGGACCGGCGAGCGTCGTTGATCTGGCGCGGGTGGCTTTTTGGCTGGAGTATTGGGATTAATCACCTTCGTGCCTGGTGCTGGATTCGAGGGGAGACCGACATGAGCGAGGAAAAACCCAACAGCTGGTGGGGCACGCTGCCGGGGCTGATGACTGCCGCCGCTGCTGTGATCACCGCGCTGACCGGACTTCTTATCGGGCTGGGCCAGCTAGGCGTGTTCGACGCCGGGAGGTCTGGCAGCGTGTCGGGTCCGCCGACCGCCGTCGGGCCTTCACAGCCAGGGGCTGCAACCCAAACCGGCAATTCGCCCCGGAACGGCAATTCACAACAGAGCGGCAGCCCGGCTGCAGACCCCGGCATTTCACCCGACGGAAGCCCCGGATGGACAGTTACCCTGCCGGACCAGCGCAAATACCGCTCTGGCGACGTAGAGTATGAGCTGCTTCGGGCGCAGGCCCGGCCTGATGCCGACGGGAAGATCACCCTGACGTTCTCCGTGCGGTGCACCAATTACGGCCGGTATGACCTCAACTTCTGGGATTCCACGTTCCGCCTCAACGTGGCAGGGATCAGCACCGCCCCCGACTCCGGACTGAACGAACTGGTCGCGGGCGACGCAAGCAAGGCGGGTGATGTCACCTTCACGGTTCCGGCCTCCACGCGTGAAGCGGCACTGCGCATCAAGTTCCTGGGGGGCGAGAGCACAGTCAAGGTGCTTGTGGCCTCGCCCTGACAGGAACGGCCTTACCTTGAGGGTGTCACCACCATGGCGGAGCCTCCGCCGCGCCTGACCGGCTCGGCTGCGGCGACCATGCGTCCGTCGGACTTGAACTCGATGGCCGTGGCTGCGCCGATCTCGGCTGCCGAGGTGAACGCATCTCCGGACGGTGTGAACACGTGGCCGAACGGCATCAGCCGCTTCTCGTACTTCGCGATGAAGCCAGGCTCCGCGGTGACCTTGGCCGAGTTCCGCTGCGCCGCCCGCGGAGCCGCAATGGCATCGGGGATGCTCATGCCCAGGTCCACCCTGTTCAGGATCGTCTGGAGAACGGTGGTGATAATCGTCGAACCGCCGGGGGAACCGAGTGCCAGGAACGGCTCGCCGTCTTCGAGGACAATCGTCGGCGACATCGAGGACCGCGGGCGCTTGTTGGGCTCAATCCGGTTCGGGTCCTTGGGGTCGTACACCGTGGAGAAGTCCGTCAGCTCGTTGTTGAGCAGGAACCCGCGGTCGGGGACTACAATGCCTGAGCCGCCGGTCTGCTCGATCGTGAGGGTGTACTCGACGACGTTGCCCCACTTGTCCGCGACCGTCAGGTTGGTAGTGGAGATGTTCTCGGTGTCCTTCTCACTGGCGGGGGCCGCCGCAATGGCCGGGCACGCGCCGTCGTAATTGGCCACGTCGCCGGGAGCCACCGGCTTCACGGCTGCAACCTTCGGGTTGATCTCGCACGAGCGTTCCTTGCCGAACAGCGGGTCGGTCAGGGCATCGGTGGGAACATCGACGAACGCCGGATCGCCGACGTACTTGCCGCGGTCCGCAAAGGCGAGCGCGCTCGCCTCAAGGTAATGGTGCAGCGCGCTCGGCGTGGACATCCCGGAAAGGTCGAACGGCTCAAGAATGTTCAGCGCCTCGCCCACCGTGGTGCCGCCGCTGCTCGACGGCGCCATGCCGTAGACGTCCAGGCCGCGGTATTCCACATGGGTGGGCGCCTGGTCCAGGGCGACGTATTTGGCGAGGTCAGCCGTGGTCAGGTGCCCCGCCGGGACGGGCAGCTTGGTGGTTGCGGTCTTCGGCGGAGCCTGGACAGTATCTGCCATCTCCTTCGCGAGGTCCCCGTGATAGAAGGCGCGGGTTCCCTTCTCAGCGAGCAGCCGGTAGGTGGCCGCAAGGTCCGGGTTCCGGAAGATGCTGTCGACGGCGGGTGCGTCACCACCGGGGAGGAATAGCTCGCTGGTGGAGGTGAACGCCTCGAAGCGGAGCTTGTTGTCGAGGGTCTGCTGGCGGAACGTCTCGTCCACTACAAAACCGCGGTCCGCCACTTCGATGGCAGGCTCGAGGACGTCATCGAGGTCCTTGGTTCCCCAGCGGTCCAGCGCGCGCTCCCAGGTGGCCGGTGTGCCGGGCACGCCCACGGAGACGCCGCTGGTGACGAGCTCCGGGGTGAAGTTGTAGGGCTTGCCGGTCTTCGGATCGATGAAGGCGTCGCGCGGCATGGCGGCGGGCGCTGTCTCGCGGCCGTCGATGGTGCTCACGTGGCCGGTGTGTGCGCTGTAGAACAGGAAGTAGCCTCCGCCGCCGATGCCGGCGCTGTACGGCTCGGTCACGCCGAGGGTGGCTGCAGCGGCCACGGCTGCGTCTGCAGCGTTGCCTCCGCTGCGGAGGATGTCGATGGCCGCGGCGGATGCCTCCGGGTCAACGGTGCTCACTGCCCCGCCGTACCCGGTGGCGGTCGCGGTCTTTTCTGTGACCCGCTCATCAGCGAACGCGGGAGTGGCGGCGGCCCCCGCCGTCACACTCAACGCCAGTGCAGTGGTGACGGCAGCTGTTCGGCTTCTCAGGTATGACATGGTCGCTCCCGGGTTCGTGTAATGCGGGTGGACGGTAATGTCACGCTACTCCGCCGCGGAAGGACACTCAACGGCGAAAACATTCGCCGGAAGCGGACTCAGCGGGCGTGCGATTCATCCGCGGCGGCACCCTGCCGGCGGCTGGCATACAGGAACGGCACGGCGAGTATCTGGAGCACGCCGCTGACCGCCAGCGACGCCGGGTAGCCGGACACGTCGGCGGTCCGCCCCAGCAGCGGCTGCACCACCACGCCGCCGCTCGACCCCATGAGGGACGCGAAACTGAGCACCGTCGCCCGCTGCCTGGACTCGATCATGTCATTGAGGTAAGCCTGCCCCACGGGAGTCCCCACCTCGGCCACGAGGGCCCACAGAGCCAGCAGCACCAGGGCCACCCAGAACTCCCGGGTGAAGCCGAGCGCCACCAGGATCACCGCGCTCCCCGCTCCGCTGAGGATCAGTACCGTGGTGCGCTTGCGGACCAGGCGCCGGACGCGCGGTGCCAGCCAGCCGCCAAGAATCTCCGCCCCGGCAACGATGGCCGCCGCAAGGCCCGCGATGGCGTACGCGCCGCGGTCGCCGAACAGCTCAAGCAGGAACGGCTGCAGGGCATAGAAAACATAAATCCCGACTCCGGCCGTAAACGGCGCGGACAGCATCACGTAGCGCACGGGCGGATTTTTCAGGCCCTTCTCAATGGAGGCCGCCAGCACGGCCCGCGTCGCCCGAAGGGGATGTGCTGAGCGTTCGGGGGTGAAGCCGACGTCGTGCATCAGCCACAGGGCCACCGTGAACATCGCCATCAGCACGCCTACCCGCAGCAGGAAAGGCACACCCAGGTCCGTGGCCTGGGCGATCACGCCGCCGGCGACAGACCCGATGAGCATGGCGGTGCCGGACACCATCTGGCCGCGCCCGAGCACCGTCTCCAGCGCGCCGTCGTACCCGGAGAAGTGCAGCGCATCCACCAGCCAGGCCTCCACCGCGCCGGAGAAGAAAGTGAAGCCCAGGCCCAGCAGCACGGACACCACCGCCCACGACCAGAACGGCGCGGAGAGTTGCCACAGAAAATAGTAGAGGAGCGTCGAGACGGACAGCGTGGCGGTGCCGAGCAGGAAGGAAACCCGGCGGCCCCAGCCGTCGGCCACCACTCCGGTGGGCACCTCGAAAATGACCATCCCGGCGGTGAAGAACGCGTTCGCGGCAAAGGCTTCGAGGTTGGAGAGCCCGGCATCGAGCAGGAAGAGCGTGTTGATGCCCCAGATGAAGGAGGCCGCAAGGGTATTTCCCAGCGTCAACGTCAGGTAGATGCGCTGCACCTTGCGGGCTGCCGGGTTCATCGCCCCGCTGTCCGTCCCGGCGCGAAGTTGGGGCACGCACCCATTCTCTCCGTGTTTACGGAGGGCCGCCAGAGACCCTTTTATCGCCGCCCGTTCGGGCGTAGCGTCGTGCCCAAGGGAGTTGGCGGCAGCCTGGTAGTGCGGCTCCGGTCCGCACGGCGCCGCTTTCTTCTTGAGCCGTCGAAGGAGGCGGGAATGGCTGCTGGCTGGAATGCTGATACGGCTGCCGGCCCTGTAGGAACGGGCACGGTCACCCTGGTGGAAGGCTCGTCCTTCTGCATTTCCTTGGCGAACGGGGATATCCATCCGGAGCATCCGCACGGGGTCTTTCATGAGGACACCCGGATCCTGTCCCGCTGGAACCTGTCCGTGAACGGCCAGCCCCTGGAGCCGCTGACGGCGGAGACCAAGGAGCCTTACCGGGCACTGTTCATCGGCCGTGTCCCCCGCTCCGATGGGTACGCGGACAGCCCCCTGATCGTCGAACGGCTGCGGGAGGTGGGCGCCGGCATCCTCGAGGAGATCACCATCCGGAACTACTCCGCGGAGGCCACCGAATGCGTCGTTTCCCTCACCGTTGAATCTGATTTCGCGGACCTTTTCGAGGTGAAGGAAGCACGTGTCCAGCGGCGCTGGGAGGAGTCCCGCCAGCCCGAGGGCGACTCCCTGGTGATCAGGGCCAGTTGGCAGAATCTGGTGAAGGGCGTCGTCGTTGATGCCCGCGGCGCCGAGGTCACCTCAGATTCCGTCACTTACCGGACAGTGGTCCCTGCCCGCGGCGAATGGAGCTCGCGGGTAAGCGTGGCGCCTGCCGCCGACGGCGGCGGGGTCCCGCCGTCGTCCTTGGTCCGCCCGGTCGGCGAGGTGTCATCGAGCGACCGCCGCCGGCAGGAATGGGTGGCCAAAATTCCCAAGCTGCACATGGGCAACCGCTCCATAGAAAGGACCTTGCGCCGCAGCTATGATGACCTGGGCGCGCTCCGGATCGAGGACCCGGCGCATCCCGAGCGGATTGTCGTGGCTGCGGGGGCGCCCTGGTTCATGACGCTGTTTGGCCGGGACTCGTTGTGGGCGTCGGAAATGGCGCTGCCGGTGGATCCCTCCCTGGCGCTGGGCACCCTGCAGACGCTGGCCGACCGGCAGGGCAAAGTGGTGGACCCCATGAGCGAGGAGGAGCCCGGGAAGATCCTGCACGAGGTCAGGCTGGGTGTCTCCAGCGGGCTGGCGCTGGGCGGCAAGTCCGCGTACTACGGGAGCGTCGACGCCACCCCGCAGTTCGTCATGGCGCTCGGTTCGGTCAGCCGCTGGGGATTCGGCCGGGACACCATCGCCGCGCTGCTGCCCCACGCAGACCGGGCGCTGGACTGGGTGCGGAACTACGGCGACAAGGACGGCGACGGATTCGTCGAGTATGAGCGACTCAACGACCAGGGCCTGATCAACCAGGGCTGGAAGGACTCGTGGGACGGCATCAACTTTGCCGACGGGACGCTGGCGAAGCCGCCGATCGCGCTCTGCGAAGTCCAGGCCCTGGTGTACTCGGCGTTTATGTCCCGGGCGTGGATGGCGTACGACGCCGGCGACGCAGCTTTGGCGGCAAAGCTTACGGAGGAAGCGGCGCAGCTGAAGAAGAAATTCAACGAACAGTTCTGGCTGCCCGACCGCGGCTACTACGCTGTGGCGCTCGACCGGGACAAGCGGCCCGTTGACGCGTGCACGTCCAACATGGGGCAGTGCCTGTGGCACGGCATTGTGGATGACGACAAGCTGCCGCTGGTGGCCGAGCGCCTGATGTCGCCGGAGATGTTCAGCGGCTGGGGCGTCCGGACGCTGGGCACCGACATGGGCGCCTATAATCCCGCCAGCTACCACAACGGCTCGGTCTGGCCGCACGACAATGCCATCATCGCCGTTGGCCTGCTGCGCTACGGCTTCGTGGAGGAGGCGCAGCGGATCTCCACCGCCCTGCTGGAGGCAGCCGATTACACGGACGGCCGGCTCCCGGAACTGTTCTGCGGCTTCAGCCGGGACCAGGTCACGGAGCCGGTGCCGTATCCGACGGCGTGCTCCCCGCAGGCGTGGGCGGCCACCACACCGATCATGCTGGTGACCAGCCTCATGCGGTACGACGCGCACGTGTCCCGAGGCGGCGTGTGGATGGACCCGGTCCTGCCGGAATCCTACGGAGACCTGCATATTACGAACGCCCCCATGGGCGGCGGCCGGATCACCATCAAGGTCACGGATTCCGAACCCTCCGTGCTGGGACTCCCGGAAGGACTGACCTTCCACCGCGAGCACCGGCCCTGGCTGACGGAGCTGATGGCGGAGGCCGGGCTGGGAAAGTAGGGGCCGCCGTCGTTCCTTGGGAGCCGTTCTTCGGGAGCTGTTCTTCGGGTGCGGCGGGCTAGGGGCGGCGGTCCAGCGCCTCCAGGAGCCGCCGGACCGAACCGCCAAGGTTCCAATCAGCGGTGAGCTGCTCGAGTTCCGCACGTGCCTCGCCGGCTACCGGCTGCAGTTCGGCGCCCGCCTCCTCAAGGGAGGGCAGTTCCAGGTTGCGCACAACATTGACGACGTCGGGAGCCACCTTGAGGTAGCCGGCGGCGGCCGCAAGCTTGGACCGCACCGAGGCAGACACGCCGCCTGCCGGATCCGCCGCCGCCGCGAGCAGCCCCTCGAGGGTGCCGTGTTCCAGGAGCAGGGCGGCGGCGGTCTTCTCGCCGATGCCGGCGACGCCCGGCAGCCCGTCCGAGGCGTCACCGCGGAGGGTTGCGTAGTCGGCATACTGCTGGGGCAGCACCCGGTACTTCCCGACGACCGCGGCGTCAGTCATGATCTCAAGGTTCTTCATGCCGCGGGCGGTGTAGATCACGCGGACCTGCCGGGCGTCGTCGACCAGCTGGAAGAGGTCCCGATCCCCCGTCACCACGTCCACGGGAAGGTCCGCGTGGCTGGCGTAGGTGCCCACGACGTCGTCGGCCTCATGTTCGGGTGCGCCCACAACGGCAATGCCGGCGAGATCCAGGACGTGGCGGATCAGCGGGAGCTGCGCCTCCAGCCCGTCCGGCACCACCTCCACATCAGCCGCGCCGGCCACTGCTTCCGCCACCCGGTGCGACTTGTAGGTCGGAATGAGGTCCACCCGCCACTGCGGACGCCAGTCGTCGTCCCAGCACGCCACCAGATGCGTGGCGCCGTAGTCGGTGGTGAGCCGCGCGATCATGTCGAGCAGGCCGCGCACGGCATTGACCGGGGTGCCGTCAGCGCGGCGGATGGTGTCCGGCAGCCCGTAGAAGGCACGGAAGTACAGGGAGGCGGTGTCGAGCAGCATCAGGCGGTTGACCATGACTGATCCTGACACGGATTCACCGCACCGTGCCCGTAACACGGGGCGAAAGTGGGAGGATGGGCCCATGGAATTGCACATCACCGGCGACGACGCCGCCGACAAACTGCTCAGCGATGACGCCTTCGCCCTGCTCACCGGCATGCTGCTGGACCAGCAGGTGACCATGGAGTCCGCGTTTGCCGGCCCCGAGAAAATCCGTACGCGCATCGGCTCCATCAGTCCGGCCGCCGTCGCCGAATATGACCCGGCAGGCTTCGTTGAAGTCTTCAAGGAACGCCCGGCAGTGCACCGCTTCCCCGGCTCCATGGCCGCCCGCGTCCAGGCGCTCGCCGAGGCTGTGCAGAGCGACTGGGATGGCGAAACGACCGCCATCTGGACCCGGGATGAGCCGGATGGCAAGGAAGTGCTCCGCCGGCTGAAGGCCCTGCCGGGGTTCGGTGATCAGAAGGCCAGGATTTTCCTGGCGCTGCTCGGCAAGCAGTGCGGGCTCCAGGCGCCGGGCTGGCGCGAGGCCGCCGGCCATTACGGCGAGGAGGGTTCGTACCTCTCTGTTGCGGACATCGTGGACCCCGAGTCGCTGACCAAGGTGCGCGCCAGCAAGCAGGCTGCCAAGGCCGCCGCTAAGGCCGCCAAGGCGCCCGCCGCGGGTTAGTGATTCGAAGTACGACGGCGGGCGGTTGCCTTGGACTGCCGGGTGCTTGGCTGCCTGACACTCGCCTATTAAGTACTCGCCACCTCAGTACTCGCCCTTGATCACGAAGTAGGAGCCGCGGATCACCCCGGCCAGCTTCGACTTCTGGCGCGCGAACTTGAAGTTTGATGCCAGTTCCTCGGGGACTTCCATGCCCTCTGAGAGCTTGAATCCCACTGCCCGCTTGCTTCCCTCCTCAAGGCCGTACATCACGTTGATGGAAAGCCCGGATTCGTAGAACACGTAGGCCATCCGGAACCCGTCCACCTCGAAGGACGTCACCTCCAGCGGACGGGATGAGATGACGATGTTGCGCTCCTCGGCGAGGATGCGGTTCACCCACTCAAGGGTGTCCGGTGCGTCGCCTGCCGGCTGGACGGTGAAGACGTGGCCGTACTTGTTCATGTAGTAGCGCGCCTCGTTGGCGCGCAGTCCGGCCAGGGTTTCCGCCACCGGGGACGGCTCCAGACCCACGGTGGATACGTTCTGGAAGTCTACGGTGTATGGCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP019304|4827052:4884143|4827620_4829570_-|WP_076803267.1|plate|DBSCAN-SWA
MLPSPNLDDRRFQDLVDDAKRMVAHYCPEWTDHNVSDPGVTLIETFAFMVDELFYRLNRVPDRLYIAFLELLGVTLHPPTAASVELLMRLSAPQPDAVVIPKGTEASTRRTEEEEAVVFATTRELTVPPRRLAHVLTQTDGAVTVARTEALHGDSSFPCFGSPPVPGDALLLGLNDAAPSCAVVLRFECEVRGVGVNPNNPPLVWEAWDGDSWVPCDLDSDGTGGLNRPGDVVVHLPHRHAASVQGGTRAGWLRCRVVEPLAGYPSYSASPTVHSAAAFTIGGSVPAVHAEAIYDEVIGMSEGVPGQSFELGRHPVLPGGDGFVVEVAAGSGWETWTEVDSFAGSEPGDRVMVLDRTTGVVHFPPAVREPDGSLRSYGAVPPAGSPIRIPCYSTGGGPRGNVAARALSVLRSSIPFVNSVENRRGAHGGVAGETIEQAKERGPLALRTRDRAITAEDYEQLAKRAAPDIARVRCIPADGADEAGGVRILVVPGAVPDKDGRLTFRDLVPDSGLLAEVAGYLDERRPVGARLLVEPPFYRGVTVVAQLTARPRVSAERLRVDALRALYSYFDPIRGGPDGEGWPFGRPVHAGEVHAVLQSLAGTEIVDEVYVFAADPLTGKRGEPQQRIEVNRNALVFSFDHRVRVSEGT
>NZ_CP019304|4827052:4884143|4827052_4827619_-|WP_076803266.1|tail|DBSCAN-SWA
MRGMVPGLGSAVPLASRLPAVLQEDAFLQRFLLAFDDALAPVFTTLDGLACYLDPRLAPEDFLDWLADWVGVRVHDSWSTDQRRDVVAHAAEIHRRRGTVPGLADAVRLAVGGVRDVVIEDSGGAAWSQTPGADLPGQATAKLHVKVYADAAKDVSVPRLERIISSVKPAHVPHTVEVLSSASSSKED
>NZ_CP019304|4827052:4884143|4876426_4878253_-|WP_076803297.1|DBSCAN-SWA
MSYLRSRTAAVTTALALSVTAGAAATPAFADERVTEKTATATGYGGAVSTVDPEASAAAIDILRSGGNAADAAVAAAATLGVTEPYSAGIGGGGYFLFYSAHTGHVSTIDGRETAPAAMPRDAFIDPKTGKPYNFTPELVTSGVSVGVPGTPATWERALDRWGTKDLDDVLEPAIEVADRGFVVDETFRQQTLDNKLRFEAFTSTSELFLPGGDAPAVDSIFRNPDLAATYRLLAEKGTRAFYHGDLAKEMADTVQAPPKTATTKLPVPAGHLTTADLAKYVALDQAPTHVEYRGLDVYGMAPSSSGGTTVGEALNILEPFDLSGMSTPSALHHYLEASALAFADRGKYVGDPAFVDVPTDALTDPLFGKERSCEINPKVAAVKPVAPGDVANYDGACPAIAAAPASEKDTENISTTNLTVADKWGNVVEYTLTIEQTGGSGIVVPDRGFLLNNELTDFSTVYDPKDPNRIEPNKRPRSSMSPTIVLEDGEPFLALGSPGGSTIITTVLQTILNRVDLGMSIPDAIAAPRAAQRNSAKVTAEPGFIAKYEKRLMPFGHVFTPSGDAFTSAAEIGAATAIEFKSDGRMVAAAEPVRRGGGSAMVVTPSR
>NZ_CP019304|4827052:4884143|4850451_4851474_-|WP_076803281.1|DBSCAN-SWA
MASEQTTLSVDGPNGPREMRISSPSRVLWPELGLTKLDLARYFVDVGEAFIRANGDRPVALQRFSGDVDGEMFFSKNPPKGAPDFIRTVKVVFPSARSHPMLVFDEPAAVVWAAQMNTVVFHPWPSHAVNSDNPDQLRIDLDPQPGTDYDDAIPAALELRKVLAEAGLDAFLKTSGNRGLHVYAPIEPTREFLDVRHAVIAAARELERRMPDRVTTNWWKEERGERIFVDFNQANRDRTIAGAYSPRALPHASVSCPITWDELADVRPKDFTILTVPDRLKTIGDPWADMHAKPGTIDTLLEWWERDIGNGLGELPFPPDYPKMPGEPPRVQPSRAKKPE
>NZ_CP019304|4827052:4884143|4848957_4849275_+|WP_076803279.1|DBSCAN-SWA
MPTGPALRVGDTALCSLSDGPKPHVGGPVTPAAGVPTVLIGGMPAAVANALPGGIVCVSPAPNGIAAGSLTVLIGGFPAARVGDLSLHGTPVGPGPGCPTVIIGG
>NZ_CP019304|4827052:4884143|4831838_4832681_-|WP_076803269.1|DBSCAN-SWA
MATVAAPAPAKGAVGSTNPAATAAGGSGGRGGEKALELSHAYLELFEPSLDGSLDKPGPRLGQIDFQFNPKELTMGKSASWAREKAKGNGKAGPPQYTGPMPSKLSLEMFFDASGKQDDAVVQRVKALFACCTPTEASLKQKKASPPWVMFRWGKLTEFHAYVSSVQAKYTLFTAAGLPVRAICTVTLEEISGDPPKQNPSSGGLVPRRVHTLVEGDTLAGIAYREYGDPSLWRAVAAANGIDDPMRLRPGSSLLLPAVDELASGTPANGSRMPEVVRGA
>NZ_CP019304|4827052:4884143|4847267_4847888_-|WP_076803277.1|DBSCAN-SWA
MEPITVKVHARDPISEAGVASELRARPEVRVVRAPNAEARVVVVVADSVDEDALTLLRIVQRKGAARAVLVAGRLDDGDLVKAVETGVVGIVRRSEATPDRLISVILAAAAGEGSVPPDLLGRLLDQVGKLQRHVLGPRGIMFTGLAPREVEVLRLLADGLDTCEIARKLAYSERTVKNVVHDVTTKLQLRNRSHAVAYALREGLI
>NZ_CP019304|4827052:4884143|4854749_4856771_+|WP_157365330.1|DBSCAN-SWA
MAPTGSEDAPLLDPNNTPRVKVPFRPVISNAALKGASTPGVASALLKRPPRGSLMAPLEFLVKTSQFGSRRNPITGQLGEFHYGQDFGAACGTRVYAADAGVVRAAGWHPWGGGNRLEIDHGNGLITTYNHLLKLGAEKGSKIRVGEVVAKVGTSGSSTGCHLHFEVIENGQHKDPNRWTLLGIRQIDRLALDDRMISFDPSSVKTLTWTIPTIAGKTFSTKEPAPPPQPPHCSTKPLPSDCPAPDKCRFDPQAPGCTPTDKCKTNPQAPGCTPTDKCKTNPQAPGCTPTDKCKTNPQAPGCTPTDTCKTNPQAPGCTPSPECTVTAGIPMAPGCALPPGCAVQADGTMPANCPLPAGCGVKAGVAMSANCPLPAGCVVQADGTMPANCPLPAGCVVQADGTMPANCPLPAGCVVQADGTMPANCPLPAGCVVQADGTMPANCPLPAGCVVQADGTMPANCPLPAGCVVQADGTMPANCPLPAGCTAQAGVAMPNGCPLPAGCVVQADGTMPANCPLPAGCTVQAGVAMPNGCPLPAGCVIQADGTMPPNCPLPAGCAYQSNQPVTPNCPLPAACATQANTPVPDGCPLPANCAYQAGVAMPANCPLPTGCGVQPQLPATCPLPLECQLPPEQLPAWCSQPPAPGQELEPSASHPSWTKSAAGESPKFQELLN
>NZ_CP019304|4827052:4884143|4865347_4867087_-|WP_076803289.1|DBSCAN-SWA
MDNSVAAAEVLEALGASALALAAELRGAADPGAAGGDFQPDPVDPLGEQATACLDGLRVVGGMEARLAAVKVELAAGYVTADAAMAVPVGSPQDAAVRQMAVRAEVAGALTISEGAAERLLVESDMLTRERPMTLAALQLGRISWQHARIMCDETEGLSPEAAAAFEAHFLDPDAPNAARGCFAGELAPGRFRAKARYWRERHHPDSIETRHSRSVKDRRLEYSPDRDGMAWISAFLPADQAAGIWNRTTAIARGLQGPTEIRTLTQLRADVFSTSLLRPAPGITGGAAGAGQGGSFPGGSAPAGEMTAGEVPSPQAQVLVTVPVFSLLGHTDEPATLDGYGPIPASMARRLVANGATSFFRVLTDPRDGAPLEIGRTSYRLTKPMRQWLRLRDAKCTFPNCTNHSLDNDADHILAWADGGGTGVTNLGQPCPKHHRLKHATAWRPVGATLESPPGWISPSGRHYPAEHQDWEPPTWPDNFAPGNFAPDNFAPDNFQPGWSDASPSQDCPELPPGRALPEPPDWFGAPSGHAEPEPSDWPDPPDQPHDPQDFDEIDERDDPEPPLPLDPWPNWSSVTAA
>NZ_CP019304|4827052:4884143|4867893_4868598_-|WP_076803291.1|DBSCAN-SWA
MSGDDAGGFQLSLFQSWQLRQGGEALHVPLRQQRLITALALKGPRSRSYLVGLLWPAHSEPKALDSLRVSVHLIARQVPGLLANGGAVLSLNDTVEVDLHRLHQEILQPGLGCGDGHAAAFLSDLRRADLLPGWYEDWVMAEQAEFRRARLHALVGLAGELFGRAEYRLALEASEAALDLEPLYEQAVRVVVEVEQLQGNRVAALRAFENYKARLMAEMGLVPSEALQKMVAEG
>NZ_CP019304|4827052:4884143|4843368_4844118_-|WP_076803274.1|DBSCAN-SWA
MHSHDYDQPDADSLRAKSPRAEAPDPALLYKAAAAGRTDVVGSRGILALQRAVGNSGVRGVAEEERSPVLDVVSSGGGQPLEEPVRADMEGRLGHSFSDVRVHTGDAAHDSAASVNAHAYTVGSNIVFQRDKYDPGSDTGRTMLAHELTHVVQQRSGPVDGTATGTGVRVSDPSDRFEREAAATAERAMSAPAAPAAQRVEGGSAVVQRQAEDAAVQREDEDEEKETAQGSFMAGAAVQRDEAEEEESG
>NZ_CP019304|4827052:4884143|4833138_4833894_-|WP_076803271.1|DBSCAN-SWA
MAPGSSAAGVMAKGMSGPERMPAAYRADSDSGYQQGESGPAAPGYNELMPLGEVTDEPKPSAAVGSVFQSIRPLAVQSLQRTVDFGGAVPAGAGHSPSRSNSRETNGDGVVYAPAPNPIAPNPVALTLAAPAAEPRAGEATGPAEDSSGTIQRLSLPEGPDHAARAATGQGSTEPGISAASLPEEASQAPQVGTASPATEHSTAGKPGSALAVTPDQLEELAKRLAGPLIRRIKAEMLLDRERRGLRTDSN
>NZ_CP019304|4827052:4884143|4875782_4876415_+|WP_076803296.1|DBSCAN-SWA
MSEEKPNSWWGTLPGLMTAAAAVITALTGLLIGLGQLGVFDAGRSGSVSGPPTAVGPSQPGAATQTGNSPRNGNSQQSGSPAADPGISPDGSPGWTVTLPDQRKYRSGDVEYELLRAQARPDADGKITLTFSVRCTNYGRYDLNFWDSTFRLNVAGISTAPDSGLNELVAGDASKAGDVTFTVPASTREAALRIKFLGGESTVKVLVASP
>NZ_CP019304|4827052:4884143|4846322_4846979_-|WP_076803276.1|DBSCAN-SWA
MIAQVDEALRTLIRTDALNGSEVDVVFDAPTKDWAARRNAPTVNLYLYDIREDVRRRERGLSEQRGDDGHVRTRRPAPRHYKLSYLVTAWTQRPEDEHRLLDQLLRCFLKYEALPDELVVGQLAETGLVVPLTVGLPPPEDRAFADVWSALGGELKPSLDIVVIAPVDTGIVYQAGPPASQGTHLDMSDLLDGGADVGRHQHVAPPAPARDNGKRQAR
>NZ_CP019304|4827052:4884143|4883006_4883594_+|WP_076803301.1|DBSCAN-SWA
MELHITGDDAADKLLSDDAFALLTGMLLDQQVTMESAFAGPEKIRTRIGSISPAAVAEYDPAGFVEVFKERPAVHRFPGSMAARVQALAEAVQSDWDGETTAIWTRDEPDGKEVLRRLKALPGFGDQKARIFLALLGKQCGLQAPGWREAAGHYGEEGSYLSVADIVDPESLTKVRASKQAAKAAAKAAKAPAAG
>NZ_CP019304|4827052:4884143|4837276_4838833_-|WP_076803273.1|tail|DBSCAN-SWA
MPNYLSPGVYVNEVEAGTRPIEGVGTAVAAFVGLASKGPDNQPTLVSNWTQFAETFGDFIPGSYLAHAVYGYFLNGGGNCYVVRIGADGARDEKPKQAPKAVTAAPTAEIGGYRLTAKSNAANPKPVSVEIADAGGENPSEDQFKIVITVEGKPPEVWDNVTTKRGPNNAATKVSAESKIVTLEEIATGGALVKPDKGTIQLVQPEPEPEPPTADELNADDYVGDAADRTGFSGLEAVDEVTMVAVPDLMAAYEQGSIDAETLKAVQLAAIAHCELMGDRVAIIDPPPNLNAQQIKDWRMDGGGFDSKFAALYWPWVKVFDPATGTNRFVPPSGHMAGVWARNDDTRGVHKAPANEVVRGVTSLQTQITKTEQELLNPIGVNCIRTFPGRGIRVWGARTLSSDAEWRYLNVRRLFNYLEESILQGTQWAVFEPNDPALWARIRRTISAFLTNEWRKGALFGVTPEQAFFVKCDAETNPAEGIDAGQVVCQIGVAPVKPAEFVIFQLSQFSGGTSLVSE
>NZ_CP019304|4827052:4884143|4832696_4833131_-|WP_076803270.1|tail|DBSCAN-SWA
MLEDVATAVSVRYTVALDNADLGTFSTCEGLGCEVVLETREEGGNNAFIWQLPTRLKYPNITLTRPLGKDTEKIAKWFAGMASGYTRCTGTIEAMTANGTKIAGWELYDVVPVRWKGPSFNPDQPKVIMETLEIAHHGFVAKLG
>NZ_CP019304|4827052:4884143|4844236_4846315_-|WP_076803275.1|DBSCAN-SWA
MGQNPSLAHLLGRISVVEERIRLLVAMRRAEDPQPDDPFRGLYLSDEAVDRLLEGEQPALRNSNGGLGAASARYRECEELAETAQAAGHPLRLRNLADKFGLSGLDVDLLLVALAADLDPRFEQFFGYLNDDVTRRRPSVAVALALCGEPLYAAGARARLLSGPLIWGGLLAVEDPDRPLPGRALRVPDRVVGHLLGDDAPDPALAAVLASPPEVTWGDPGPLARALDAGIRLAYLREPATGSGRILAAEALSSSGYPAIHLDLGRLANEREPLALVDAAVREARLRGAGLVAAPLAAISDHPQVLEVLHAEPQPVLFVGDAVWDPAWTSRPPLLVDVAASSSNERLELWRAALGSHDGLDVEAATSAFRLRPEQVVRAAGSALVQAALAEDGRATAAQLRAGARGENGSALDRLARRIEPAVGWGDLVLPDAVLQALQEVALRARHRERVLGDWSMRPGAGRGHGVAALFAGDSGTGKTMSAEVVAGELGLDLYVVDLATVVDKYVGETEKNLERIFAAAAGVNGVLLFDEADAVFGRRSEVKDAHDRYANIESAYLLQRMETFDGLAILATNLRANIDEAFTRRLDVLVDFPLPDAAHRTVLWDRCLRTLDRSADLDLAFLGKAFELAGGSIRSSAITAAYLAADDGGTVTMRHLVTAVQREYRKLGRLMLESEFGPYWGMLSTAKNSMG
>NZ_CP019304|4827052:4884143|4862497_4865245_-|WP_076803288.1|DBSCAN-SWA
MTSALPLASSAPFNLDSIGSGLVFAESLGELAGVLQKQGAGGAAVVQAPPGTGKTTLVPPLVANLAQGSTAEGQPRIVVTQPRRVAARSAARRLAALDGTKLGDRVGYTVRGERQAGPATLIEFVTPGILLRRLLADPGLEGTAAVILDEVHERGLETDLLVGLLAEVRQLRGDLMVVAMSATLDAPRFAALLGGNEEGNEDGNMGGEHGGEADGGGPAPVVDCPSALHPLETAWAPAPAARLDGRGVTRAFLDHVADTAAASHAEALAADPGTDALVFLPGVWEVSHVAGQLRTRVGPGVEILELHGQASPAAQDRAVSGRQPGEPSRIIVSTALAESSLTVPGVRLVVDSGLSREPRRDAGRGMTGLVTVSCSRASAEQRAGRAARQGPGKVVRCYDQKTLGAAPAHQTPEIAVSDLTGAALILACWGAPGGRGLALPDTPPPLAMADATEVLRELGAVGDDGHAMELGKALARIPADPRLGRALLVGSALLEERQAGSGSASPAHAGFGTAAEVVAAVAGDQRANGADLPRLVSTLRSGKDPAARRWAEEARRLDTLARQAATGVGLPLVEVPSVELPAGSAEQVGMVVALAFPGRVARRVPGDGPERYLLTSGTRAGLPAGSPLAGHEWLAVAEVARADGRDAAGTGAVIRSAAPLTADAAEAAAAHLLRDSVEAAFSQGKVTARRERRLGAIVLSSTPVPASAADGHAAVARAVEEQGLGVIGWSTSADGLRRRLALLHRELGDPWPDMSEQALLARLDDWLGPELEALAGGVSTSGIDLADPIRRLLPWPDAARLGELAPEFLEVPSGSRVRIDYPQAEDDGGRPVVAVKLQECFGWDRTPRLADGKVAVQFHLLSPARRPLAVTDDLASFWSGPYAQVRAEMRGRYPKHPWPEDPWTATATARTNARK
>NZ_CP019304|4827052:4884143|4878351_4879593_-|WP_076803298.1|DBSCAN-SWA
MNPAARKVQRIYLTLTLGNTLAASFIWGINTLFLLDAGLSNLEAFAANAFFTAGMVIFEVPTGVVADGWGRRVSFLLGTATLSVSTLLYYFLWQLSAPFWSWAVVSVLLGLGFTFFSGAVEAWLVDALHFSGYDGALETVLGRGQMVSGTAMLIGSVAGGVIAQATDLGVPFLLRVGVLMAMFTVALWLMHDVGFTPERSAHPLRATRAVLAASIEKGLKNPPVRYVMLSAPFTAGVGIYVFYALQPFLLELFGDRGAYAIAGLAAAIVAGAEILGGWLAPRVRRLVRKRTTVLILSGAGSAVILVALGFTREFWVALVLLALWALVAEVGTPVGQAYLNDMIESRQRATVLSFASLMGSSGGVVVQPLLGRTADVSGYPASLAVSGVLQILAVPFLYASRRQGAAADESHAR
>NZ_CP019304|4827052:4884143|4882000_4882939_-|WP_172804328.1|DBSCAN-SWA
MVNRLMLLDTASLYFRAFYGLPDTIRRADGTPVNAVRGLLDMIARLTTDYGATHLVACWDDDWRPQWRVDLIPTYKSHRVAEAVAGAADVEVVPDGLEAQLPLIRHVLDLAGIAVVGAPEHEADDVVGTYASHADLPVDVVTGDRDLFQLVDDARQVRVIYTARGMKNLEIMTDAAVVGKYRVLPQQYADYATLRGDASDGLPGVAGIGEKTAAALLLEHGTLEGLLAAAADPAGGVSASVRSKLAAAAGYLKVAPDVVNVVRNLELPSLEEAGAELQPVAGEARAELEQLTADWNLGGSVRRLLEALDRRP
>NZ_CP019304|4827052:4884143|4836344_4836773_-|WP_157365329.1|DBSCAN-SWA
MEADSPGAPRAATGAAERQPLRTEFSFELPRGYVDQDGTVHKTGVMRLATARDELLPLYDARVQENAAYTTVVLLGRVITSLGTLAAVTSAVVENMFASDVAFLQDFYRRINAEGHTRIAVTCPECSHRFTADLAGGRLGES
>NZ_CP019304|4827052:4884143|4853639_4854323_+|WP_076803283.1|DBSCAN-SWA
MPTADTPVTIAVGDGHVSGAYARPANPFATLVLAHGAGAGMEHPFMRGFTGALNDDGVATLRFNFPYREAGRKFPDRPPAAIATWRAAMADAAARSAGKSEPVWAAGKSFGGRMASMAVAEGMPAAGLVYLGYPLHPPGKPEKLRDEHLYGLTTPMLFLQGTRDTFATRELLEGVVSRIGPTATLQWCEGGDHSFAVAGNKRSAEEIGASLAAPVAAYIRANNPAGH
>NZ_CP019304|4827052:4884143|4829569_4829983_-|WP_076803268.1|DBSCAN-SWA
MGQEFIGAGWAFPLRTDRTGSIALVRDQREIEESIHLILATSPGERPMRPEFGCSVHDYVFAPANAATAGDIAYAVRVALDRWEPRITLENVAVNFEGVDAGLLLIDVQYTIRGTNDPRNLVFPFYVIPRNGEEAAS
>NZ_CP019304|4827052:4884143|4861448_4862480_+|WP_076803287.1|DBSCAN-SWA
MRIVLIAGPWYPIPPTGYGGIELVVDALARGFSRAGHEVLLACAADSTCPVPQLPGMRPSEPDFVGFTSSELSHVVNAYAGMDGMVDLVHDHTLAGPLYRGRPEGLPVVTTLHSDLNPSFTAVYGAAARDTTLIAISRSQVSSALADRVAAIIPHGMELSAVPVGQGQGGYACFLGRMCPDKGVVEAIEVARLAGIPLRIAAKMREPAEVQYFHDVVEPMLRPDVEFLGEVGGADKYKLLGEAVALLNPIQWMEPFGLVMIEAMATGTPVVATPIGSAPEVIDDGVTGYLASAPEELARLLLRAPDLDRATVRAQAEDRFSTERMVEDHLALYTRLIGVTSAR
>NZ_CP019304|4827052:4884143|4836808_4837252_-|WP_076803272.1|tail|DBSCAN-SWA
MALGDFDNSAANGFTVTIDGIEVPRVIEVSGLKTEVDKIELKQQTKDGKYVVRQLIGRPKAGELTVTRGLTQSKTITDWLKTVMEGDVAGARKTAAVALLDYKGETLKTYNFVNCWVKSVELNSLKAGATEQATEKFVICYDESTIS
>NZ_CP019304|4827052:4884143|4836189_4836348_-|WP_157365240.1|DBSCAN-SWA
MTYAADRIYEEVAYVAYHFHWPLDDILDLEHGQRLRYVREIAGINTRLSQER
>NZ_CP019304|4827052:4884143|4848145_4848958_+|WP_076803278.1|DBSCAN-SWA
MTTTASFDTPRLSIEGGAEGTTGITFRNDSEVVEEYSLRVVGPAESWAEVAPARVSLYPGHDTTADVTFRPPRSASVHAGEYLFGVQVLPTEHPEDAALPEGVVEVRPFLETTGELMPRMSQGKRGAKHNVALDNWGNVPITVELAGSDPGDLLEFELQPPELTIGPGEVQFTAVHVRPAEKIWSGTPTTRVFVVTATPEDGVPVLLDGSHVQYPILPWRTIKTVFCLLLLAAALTVAWHFSVESVRVSEPTSTNTSQGVAPNGVPNGTQ
>NZ_CP019304|4827052:4884143|4872656_4874513_-|WP_076803294.1|DBSCAN-SWA
MTGQESASRKSGAEEETRKSLRQFIRTRGAEYLKDPNISSIGVGYKMSEGSPTGELALQFTVDRKAAPDELEALGTVPIPGEIIIDGVAVPTDVIERSYRPGFRIVAEAEPPAAKVRVDPVLPGVSVAHYQGTAGTIGCIVYDKTDGEPLVLSNWHVLHGTCGALGDVVVQPGPYDDNRVDRNRLGVLKRSHLGVAGDCAVATIEGRTVNPEILGVGATPRELGEPEIGDKVLKSGRTTGLTHGVVRRVDVIAKLHYGAAGEQAIGGFEIGLDEQNLPEDGEISRGGDSGAAWLFKNADGTPGNVLAGLHFAGETGTSVDEHALACLPQSVFEKLGITLVRPDSGAIADAVAVGYDPSFLGVRLDPPTLDASLQGDAVPLDGSDIIPYTHFSLVMSAGRRFARWVGWNIDGGALKRIPRKSLSFTKDPRIPGRFQCGDELYSDNRLDRGHLARRADLLWGDLTEAEQANKDSFFFTNITPQLEDFNQSARKGVWGRIEDAVFADVDVQDLRVSVFGGPVFQANDRIYRGVPLPREYWKIVAFVEDGQLQGRAFLLTQNLNQLEALELDEFRVFQVAVREIQERTRLVFPENLRNADTFTAPESLQARDPLDRPGDIRW
>NZ_CP019304|4827052:4884143|4849315_4849858_-|WP_076803280.1|DBSCAN-SWA
MKPDFIVVPPEACTVARGDPPDTPACLFVTVDLRNQGQGVHAVELGIESKSLAAKVGLSEKKTLEAGEEPKLTEVRVNIQPDDLGQTHEVTFMADPLKTIEEADEDNNLITVKITLPTADTLPATAVCPPETMDSTDGPSSPAAEGGQLPEGGQLPEGGGSDGSSSPAGSTETVPAAEGQ
>NZ_CP019304|4827052:4884143|4883678_4884143_-|WP_076803302.1|tail|DBSCAN-SWA
MPYTVDFQNVSTVGLEPSPVAETLAGLRANEARYYMNKYGHVFTVQPAGDAPDTLEWVNRILAEERNIVISSRPLEVTSFEVDGFRMAYVFYESGLSINVMYGLEEGSKRAVGFKLSEGMEVPEELASNFKFARQKSKLAGVIRGSYFVIKGEY
>NZ_CP019304|4827052:4884143|4870031_4872707_+|WP_172804371.1|DBSCAN-SWA
MRHAFGSHRSSSDLPGEAVFHVVDGGVFDNIPIGRALTAARGRVSQRPAHRALLYLDPDSVGDSLPTSRSENLSRFLNAVGASALRLKRRESLDSEVKEYVDYVNALSLNLGRSEALAAVLSDRWSTEIAVDRRRAYVRYRASADVDLLTQVLTRPDEWQVASTVTDRRNFRALGSDELSGLDSRIIQKYRDISRQDEEGTAFRLLTSDAQALLDAAQCSFSWLRRMESESFPKELTDSIASFDALRTGIYGVINSAVILRDQAIWAVLEKSTDCAESVRHENIMAAWLSAAETNQPSRMQCWAALQSHFEVLVRYSADLTDRAADAGSHPELREWTESPWPDLTRIALLSAPDCGFTIHDLAPCLAAAGIPPVVARIRYWRIGSDERPAHACDYSLLKDGERRGAVAFALKNPSLSPCDLKDLLNPDAASLSSRFKLAGNTMANFSGFLSRDWRENDWWWGRLDAAAGISRFLETVAVDQNPRIPELDGDQELFDESTAEAPRGSRNRVTWLQDQLTDQWFGLQAAAPEDRRKARQSIRAGADSPSDLGAAYRMMLMSRGLRVLWRARPDGNLPTALGSWLLHVLLVPLFAVLPAIVHPARLAFILGFGDASLWVLARPENAVFGAQPFLLYLGLVLPGLIFLALAFVALADGHRRWRPVLEVLSGDRLLATEYRSHQRSAARKAMAGPVAVILLLVPLGLAASQARQLMVVVCLVFMGILTVATRKWAMSVPAPVHGKHPALDWGLACTGLLLAVAVPLVTELLHWSAARNWQSLAVLACSLLVLALVLTCDWLTAVGTLLTGLAASAGGILAAWGVWVLLATLRQSERTILCLFAAFVAWGLAVWWMPEITRMLRHRSDAVVTVPRRKGAEVSPPDVPGPVQRVPGLQ
>NZ_CP019304|4827052:4884143|4867242_4867884_+|WP_076803290.1|DBSCAN-SWA
MLRLPRITVEVPVLGVGDRPADYEQLAAYADGLRKPEGLHMTLLHIGILDDFAADVVAWTKGATDPAAAAVKTADWLRALPVLEGFTGTAERLVLFGGGRVSGLDVEVPQHVRDFQVSLVAALRELLEDLLVDNPDDFILSSPALGYRYPRWHPHVAIGKPKSRDHSGEGRSGEGRSRERSGSWEIRPLKVEFGPSQIRNRQLLPGPGDGGHQ
>NZ_CP019304|4827052:4884143|4851622_4853617_+|WP_157365241.1|DBSCAN-SWA
MKATGAARRRASSKETHSMVESASLDATQGPSDAREPGEQQLFRTTAAEAGLVPGSRDWNALEERYDRHFPDLSRLFRSLYGSRPDVEEQLAALVAEMARSWQDRPADLKQLDDGREDNSDWFQSNRMLGGVCYVDRYAADLEGVRARIPYFKELGLTYLHLMPLFLAPEPLSDGGYAVSSYRKVNPKLGTMDQLRALAAELRANGISLVVDFIFNHTSNEHEWAQRAAAGEPRYSDYYWIFPDRTMPDAFEQNVREIFPEDHPGSFVQLPDGRWVWATFHTFQWDLNYSNPEVFRAMAGEMLFLANLGVDILRMDAVAFIWKQLGTPCESLPEAHTLLQAFNAVCRLAAPSLLFKSEAIVHPDEVALYIDPAECQLSYNPLQMALTWEALATRNVSLLAQALERRHNIAPGTSWVNYVRSHDDIGWTFADEDAAEFGINGFDHRRFLNSFYVNRFPGSFAHGVPFQDNPRTGDCRISGTTGSLCGLEEGSAEAIRRVLLTHSVAFSTGGIPLLYLGDEVGQLNDYGYAQEDGHEADSRWVHRPQFPAEKYAKRLDPATPEGAVYAGLRRLIEVRAATPELGGTRLVPFTTNNHAVLGYQRPGVGTAVLALANFSDGPQVVSAETLSGFAAEALDLFSDVPVRIDEGLVLRPQDYAWLRVVPAD
>NZ_CP019304|4827052:4884143|4830028_4831849_-|WP_083706399.1|DBSCAN-SWA
MAHNEEFSNMLLVEVAGRPLPPDVAARLVAGYVDDSSNVPDLFLLRFTDEFSLVLEKAGFAIGAPVKLSVQQSGPGGPVPLLSGEVTALETEMDHEGLYTIVRGLDHSHRLFRGRRVEAYLQSTAADIVRKVAQRAGIKAGTIAAKGPVLQHVAQDGISDWDFLHRLAVESGVVLSVSGGELHFTPSTDSATAPAGTGGAKEDPLVLERGVNLVALRGTVTSADQVPDVEVRGWDVAAKKAIVAVAQAQTRSARLPEVDPAALAKKFGSPRYVAPPTAFDQAAQCDAAAASIASRLGGAFAEVEGLARGNPKLRAGTAVVLKGAGKPFDGQYTLSSSRHEFSPDTGYLTTFTVSHESERSLYGVAAGGNGRDAVPTVVNAVVTAAKDPENQGRVKVKFPVLSDNYESWWARTIQAGAGTSRGAVVLPEVGDEVLVAFGHGSFQQPFVLGGLYNGKDQPDKPWADHVGSTDGSVTRRAFVSRTGMLVEFLESPDGEQVLVSTSGGKQKIALVQKPDAAIEIVSEGPVNVTARKDVAVTTTTGQVTIKGKKVIVEALSDLELKGAAVKISGTATAELKAPGVKVAGDATAELSGGATTTVKGGLVRIN
>NZ_CP019304|4827052:4884143|4859235_4861365_+|WP_076803286.1|DBSCAN-SWA
MSAWNENIGAGSAGLTAVTVVEGSSFCISAESGDVFPGQPQGAFYQDTRILSRWQLTVDGVPLEPLSGQTREPYRAVFIGRPRGASGAVESPLVVEHNRTVGPGLRDDIKVHNYSEKPLTCRIQIRVDADLSDLFDVKGGKVVPSAEHSRKVRAEALQIDAIRNGIHRGVVISAQGAMVTEDALTFDADLAARGTWTASVFTTPLVDGAFPEQPFTHETAPHVGAQRYAAWEEHVPRLTVTDKNVEKVLTRSQEDLGALRIFDPEHPERAAVAAGAPWFMALFGRDSILSSYMALAVDPKLATGTLQTLAALQGKKVDPDTEEEPGRILHEVRLGVTAGLALGGSQAYYGTADATPLFVALLAELGRWGLAGDLLDSLLPHADRALDWIENYGDRDGDGFVEYQRANEHGLLNQGWKDSWDGINFADGSMAEAPIALCEVQGYVYGAYLGRALLAQQLGDTDMASKWNRKAADIKAEFNDRFWLPKKGYFAVALDKDKRPVDACASNMGHCLWSAIVDADKAPLVAERLMSPEMFTGWGIRTLASDMGAYNPVSYHNGSVWPHDTALIAGGLMRYGFVEEATRIAMGLFDAAEKFDGRLPELFCGFSRDDFPDPVPFPTSCSPQAWASAAPVHLMRILLRFDPLLPREEVCLAPVLPAAFGSFRADHVQMDSARITVQATGTEGSIDGLRQGLTLLHEPRPPLARLMRH
>NZ_CP019304|4827052:4884143|4856805_4858986_-|WP_083706488.1|DBSCAN-SWA
MSVKGTNGRGKGPGRGSSDLRRADASAGAPVDKPEGIRNVALVGHSGAGKTMLLEALLAAAGTIPRMGSIVDGNTVSDAEPSEIHQQRSVVLSVAPLVYDGVKVNLLDTPGYGDFTGELRAGLRAADAALFVVSAVDGVDAATTALWAECAQLDTPRAVVITRLDHPRANFEAALAACQRAFGQSVVPAYLPVRTDGSVTGLLGLLSGQVSEYDGESPEPAVRDASADERAAAESERGTLIEGIISESEDESLMDRYLGGEDIDADVLVGDLEKAVARGSFFPVLAASAETGLGMTELLEMLTRAFPTPLERAVPDVTDLAGEPAGPLTCDPDGPLAGEVVRTTIDPFLGRVCLVRVFSGTLREDSAVHVSGRGLAERGHEDHDSDERLAHLYSPLGANLRPIPYCVAGDICAITKIGSAETGDTVSAKDAPLLITAWDMPEPLMPLAVEAATRSDEDALAKSLGKVAAGDPTLRVERNSETHQLILWCMGEAHGEVVLDRLRDQGVKLQTVPVVTPLRETFAAPAAGHGRYVKQSGGHGQYAICDIEVEALERGAGFEFVDKTVGGVVPNQFIGSVEKGVRAQMQKGVSAGFPVVDIRVTLVGGKAHSVDSSDAAFQSAGALALREAAAAGRIQLLEPVSSVTISIPDEYVGSVMSDLSARRGRLTGTTSSGGDVTEVTAEVPDGELLRYAVQLRALTAGTGRFRRSYLRHEPVPGNVAPAAANA
>NZ_CP019304|4827052:4884143|4874509_4875544_-|WP_076803295.1|DBSCAN-SWA
MELESLPDEVLASIADRNAWRSQMAGSDTALEFLVSDLARWQPGSAVRVAFLDGDTALHADVAGATRQISDACNLELDFGVDAAGNYRRWHENDTFHAAEIRVGFNMGGYFSLVGTDSTDSTIGPPAGPVGGRPNQRSLNLGGFTTERPERWEGTVRHEFLHALAFHHSHQNMRGSCEAEFRWDDDQDYAPTTNAKGVFIPDAAGRRPGIYTYLAGPPNNWPRAKVDHNLRTVEDPAVVAGPFDSDSVMLYSFPDFFYKSSPSSCAPTGNGKDLSAGDRRGLALLYPHAAERLGDLQERAEAALAAMDGTGSSPETVEAAGGEYRDRALELLHALSGKGEGVGR
>NZ_CP019304|4827052:4884143|4879788_4881942_+|WP_076803299.1|DBSCAN-SWA
MAAGWNADTAAGPVGTGTVTLVEGSSFCISLANGDIHPEHPHGVFHEDTRILSRWNLSVNGQPLEPLTAETKEPYRALFIGRVPRSDGYADSPLIVERLREVGAGILEEITIRNYSAEATECVVSLTVESDFADLFEVKEARVQRRWEESRQPEGDSLVIRASWQNLVKGVVVDARGAEVTSDSVTYRTVVPARGEWSSRVSVAPAADGGGVPPSSLVRPVGEVSSSDRRRQEWVAKIPKLHMGNRSIERTLRRSYDDLGALRIEDPAHPERIVVAAGAPWFMTLFGRDSLWASEMALPVDPSLALGTLQTLADRQGKVVDPMSEEEPGKILHEVRLGVSSGLALGGKSAYYGSVDATPQFVMALGSVSRWGFGRDTIAALLPHADRALDWVRNYGDKDGDGFVEYERLNDQGLINQGWKDSWDGINFADGTLAKPPIALCEVQALVYSAFMSRAWMAYDAGDAALAAKLTEEAAQLKKKFNEQFWLPDRGYYAVALDRDKRPVDACTSNMGQCLWHGIVDDDKLPLVAERLMSPEMFSGWGVRTLGTDMGAYNPASYHNGSVWPHDNAIIAVGLLRYGFVEEAQRISTALLEAADYTDGRLPELFCGFSRDQVTEPVPYPTACSPQAWAATTPIMLVTSLMRYDAHVSRGGVWMDPVLPESYGDLHITNAPMGGGRITIKVTDSEPSVLGLPEGLTFHREHRPWLTELMAEAGLGK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076803266.1|4827052_4827619_-|tail	phage tail protein I	NA	NA	NA	NA
WP_076803267.1|4827620_4829570_-|plate	putative baseplate assembly protein	A0A1J0GW37	Streptomyces_phage	6.2e-12	25.3
WP_076803268.1|4829569_4829983_-	GPW/gp25 family protein	A0A1S6KZZ4	Salmonella_phage	3.1e-06	38.2
WP_083706399.1|4830028_4831849_-	VgrG-related protein	NA	NA	NA	NA
WP_076803269.1|4831838_4832681_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_076803270.1|4832696_4833131_-|tail	phage tail protein	NA	NA	NA	NA
WP_076803271.1|4833138_4833894_-	hypothetical protein	NA	NA	NA	NA
WP_157365240.1|4836189_4836348_-	hypothetical protein	NA	NA	NA	NA
WP_157365329.1|4836344_4836773_-	hypothetical protein	NA	NA	NA	NA
WP_076803272.1|4836808_4837252_-|tail	phage tail protein	NA	NA	NA	NA
WP_076803273.1|4837276_4838833_-|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.4e-67	32.8
WP_076803274.1|4843368_4844118_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_076803275.1|4844236_4846315_-	ATP-binding protein	A0A2D2W2C3	Stenotrophomonas_phage	8.3e-07	29.7
WP_076803276.1|4846322_4846979_-	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_076803277.1|4847267_4847888_-	response regulator transcription factor	NA	NA	NA	NA
WP_076803278.1|4848145_4848958_+	hypothetical protein	NA	NA	NA	NA
WP_076803279.1|4848957_4849275_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_076803280.1|4849315_4849858_-	hypothetical protein	NA	NA	NA	NA
WP_076803281.1|4850451_4851474_-	ATP-dependent DNA ligase	NA	NA	NA	NA
WP_157365241.1|4851622_4853617_+	amylosucrase	NA	NA	NA	NA
WP_076803283.1|4853639_4854323_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_157365330.1|4854749_4856771_+	peptidoglycan DD-metalloendopeptidase family protein	V5R8R0	Arthrobacter_phage	1.9e-16	46.7
WP_083706488.1|4856805_4858986_-	elongation factor G-like protein EF-G2	NA	NA	NA	NA
WP_076803286.1|4859235_4861365_+	amylo-alpha-1,6-glucosidase	NA	NA	NA	NA
WP_076803287.1|4861448_4862480_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_076803288.1|4862497_4865245_-	DEAD/DEAH box helicase	A0A1V0SIV3	Klosneuvirus	4.9e-15	25.1
WP_076803289.1|4865347_4867087_-	HNH endonuclease	NA	NA	NA	NA
WP_076803290.1|4867242_4867884_+	hypothetical protein	NA	NA	NA	NA
WP_076803291.1|4867893_4868598_-	hypothetical protein	NA	NA	NA	NA
WP_172804371.1|4870031_4872707_+	DUF3376 domain-containing protein	NA	NA	NA	NA
WP_076803294.1|4872656_4874513_-	DNA/RNA non-specific endonuclease	J7Q326	Aeropyrum_coil-shaped_virus	4.4e-07	29.7
WP_076803295.1|4874509_4875544_-	hypothetical protein	NA	NA	NA	NA
WP_076803296.1|4875782_4876415_+	hypothetical protein	NA	NA	NA	NA
WP_076803297.1|4876426_4878253_-	gamma-glutamyltransferase	NA	NA	NA	NA
WP_076803298.1|4878351_4879593_-	MFS transporter	NA	NA	NA	NA
WP_076803299.1|4879788_4881942_+	amylo-alpha-1,6-glucosidase	NA	NA	NA	NA
WP_172804328.1|4882000_4882939_-	5'-3' exonuclease	F8WQ40	Bacillus_phage	7.5e-16	31.7
WP_076803301.1|4883006_4883594_+	Fe-S cluster assembly protein HesB	NA	NA	NA	NA
WP_076803302.1|4883678_4884143_-|tail	phage tail protein	NA	NA	NA	NA