CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP019322	Methylorubrum extorquens strain PSBB040 chromosome, complete genome	2 crisprs	DEDDh,RT,csa3,cas3,WYL	0	0	4	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP019322_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019322_1

1385124-1385206

Orphan

Consensus_repeat	Method
GGACAGATGTGGCGCTCCGATGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019322_1

>merge|NZ_CP019322|1|1385124-1385206|CRISPRCasFinder
GGACAGATGTGGCGCTCCGATGGTGCCGGGGGTTTCAATGGTTTTGGCCCCGGAATAGAGGGACAGATGTGGCGCTCCGATGG

>NZ_CP019322|1|1|1385124-1385206|CRISPRCasFinder
GGACAGATGTGGCGCTCCGATGG	TGCCGGGGGTTTCAATGGTTTTGGCCCCGGAATAGAG
GGACAGATGTGGCGCTCCGATGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019322.1\|WP_076641505.1\|1385375_1386275_-\|nucleotide-binding-protein	unknown	unknown	gnl\|CDD\|378409
NZ_CP019322.1\|WP_076641503.1\|1382622_1383144_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641504.1\|1383532_1384660_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227684
NZ_CP019322.1\|WP_076641509.1\|1389796_1390000_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_155773716.1\|1380036_1380552_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_155773717.1\|1390511_1390685_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076644365.1\|1388543_1389125_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP019322.1\|WP_155773715.1\|1379389_1379890_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641510.1\|1390214_1390451_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641506.1\|1386267_1386558_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641495.1\|1376190_1376730_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197617
NZ_CP019322.1\|WP_076641496.1\|1376733_1377891_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641500.1\|1380676_1381156_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_081397078.1\|1391063_1391381_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368014
NZ_CP019322.1\|WP_076641497.1\|1377974_1379111_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641507.1\|1386580_1387990_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377306
NZ_CP019322.1\|WP_076641502.1\|1382176_1382605_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641501.1\|1381300_1381531_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641508.1\|1388101_1388539_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076641513.1\|1391448_1391685_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236558

Protein	Function_ID	Function_description	E-value
NZ_CP019322.1\|WP_076641505.1\|1385375_1386275_-\|nucleotide-binding-protein	gnl\|CDD\|378409	pfam10137, TIR-like, Predicted nucleotide-binding protein containing TIR-like domain. Members of this family of bacterial nucleotide-binding proteins contain a TIR-like domain. Their exact function has not, as yet, been defined.	2.20919e-51
NZ_CP019322.1\|WP_076644365.1\|1388543_1389125_-\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	7.6717e-51
NZ_CP019322.1\|WP_076641504.1\|1383532_1384660_-\|hypothetical-protein	gnl\|CDD\|227684	COG5397, COG5397, Uncharacterized conserved protein [Function unknown].	1.06251e-106
NZ_CP019322.1\|WP_081397078.1\|1391063_1391381_+\|hypothetical-protein	gnl\|CDD\|368014	pfam04592, SelP_N, Selenoprotein P, N terminal region. SelP is the only known eukaryotic selenoprotein that contains multiple selenocysteine (Sec) residues, and accounts for more than 50% of the selenium content of rat and human plasma. It is thought to be glycosylated. SelP may have antioxidant properties. It can attach to epithelial cells, and may protect vascular endothelial cells against peroxynitrite toxicity. The high selenium content of SelP suggests that it may be involved in selenium intercellular transport or storage. The promoter structure of bovine SelP suggest that it may be involved in countering heavy metal intoxication, and may also have a developmental function. The N-terminal region of SelP can exist independently of the C terminal region. Zebrafish selenoprotein Pb lacks the C terminal Sec-rich region, and a protein encoded by the rat SelP gene and lacking this region has also been reported. N-terminal region contains a conserved SecxxCys motif, which is similar to the CysxxCys found in thioredoxins. It is speculated that the N terminal region may adopt a thioredoxin fold and catalyze redox reactions. The N-terminal region also contains a His-rich region, which is thought to mediate heparin binding. Binding to heparan proteoglycans could account for the membrane binding properties of SelP. The function of the bacterial members of this family is uncharacterized.	7.86673e-05
NZ_CP019322.1\|WP_076641507.1\|1386580_1387990_-\|hypothetical-protein	gnl\|CDD\|377306	pfam04326, AlbA_2, Putative DNA-binding domain. This family belongs to the AlbA clan of DNA-binding domains.	0.00225911
NZ_CP019322.1\|WP_076641513.1\|1391448_1391685_-\|hypothetical-protein	gnl\|CDD\|236558	PRK09545, znuA, zinc ABC transporter substrate-binding protein ZnuA.	0.0036326
NZ_CP019322.1\|WP_076641495.1\|1376190_1376730_+\|hypothetical-protein	gnl\|CDD\|197617	smart00271, DnaJ, DnaJ molecular chaperone homology domain.	0.00349563

>NZ_CP019322.1|WP_076641504.1|1383532_1384660_-|hypothetical-protein
MKTLPNLIQIAFADLIAKAFDAEFDDAYPENGRFSKRERRGREYWYYLGYERDPDGSKKGKEVQKYVGPVSDPEITRRVERFQDIRVSYRERREIAGTLRRSGLPAPSPLEGNVVAALARGGLFQMRAVLVGSLAFQTYSGLLGVALKDALYRTEDIDIAQDYGVSIGVGADDRMEEVQEVLRGVEPSFRPVPHIGRNPSAAAFQTAKGFKVEFLTTNRGSPDIESDVSMLPALGVGATPLRFLDFLIRHPCRSVLLHDAGVAVMVPTPERYAVHKLIVSRRRIQTQESQEKASKDIAQASAIIQAKHHLRMSQDLGFAWIEAFERGDTWRQLLEEGAHLLDVAELSALELGIRKAAELEKMPDWKSYVPWRSPA
>NZ_CP019322.1|WP_076641503.1|1382622_1383144_+|hypothetical-protein
MDSTLVESIKLVGGIAGLATAGFTIWDRAFRARPWMEPHIAGRVDGRPIGLPLIDAPACLRIYNPGARTIGIGSVRFRGIPPRRMALSDDVGRDVHPRRLMPIGPGETRLFEVVWRDPEEGDDPERPVRIIVSWRPLTALLPRVPLRLGTSIGALRRLQEAELDRVQRAQRQR
>NZ_CP019322.1|WP_076641502.1|1382176_1382605_+|hypothetical-protein
MPIRREHRFFYPIDWPQLSAVIRFGRARGRCEGCGRPHGRTVFCLADGRWWDEDAVSWRDGAGRIACLAIGADDVVATVRTTRVVLATAHRNHDTADNSPANLAAFCQRCHILHDQPEHRRRRWRTLFRRKALGDLFRGPYP
>NZ_CP019322.1|WP_076641501.1|1381300_1381531_-|hypothetical-protein
MRTIQLLALATLACVTAAGSAVADERVHLTPPLFREQARATASVRPASELTTTPHLTAAAPATRKVVAEAAAISAR
>NZ_CP019322.1|WP_076641500.1|1380676_1381156_+|hypothetical-protein
MPFSKQLIDILIPADRAVLEAATYFILEACCDYGDNVGLAFVEDASYFAIHAGMAHRPDQRMMLIADSLAEALDQLELVRIARPDAGLWFSSMEVLTKIEHPNLARGVVLARGSADPDDDEDDWSIMAAHIAKCEASGQPLDMSVNASDVISTIADRLV
>NZ_CP019322.1|WP_155773716.1|1380036_1380552_+|hypothetical-protein
MLSYYENLAAALRDPSSPLGAAVQTIRDMGMPLRVVVHNQTTGQVYVADDNDHIEVAHGGIREMVTGEPWRDPGTLNPVAPAAVRRSPKRLAAHNAEVAGMLLYLVRIYRPDIAGCDRIEGFIEEMISFVNRPDNRCKLVALSDNYERWDVITGNFIKLMDEMNKTSATPH
>NZ_CP019322.1|WP_155773715.1|1379389_1379890_+|hypothetical-protein
MQGSTHFMTKSLLKLENFSPNLQATYDAATYFVLEALHETSDTVEFVLLEEAAEGGLFGITVGLPDRPALRVFWTFPDFGDAVAVFQEIRNLRPDARFFFSEWSEEDGNEIQGTDILRGMIAMRAEENRFDPDCEWTWLAEDAAGNRPENGRDYEPFYAAIAARLA
>NZ_CP019322.1|WP_076641497.1|1377974_1379111_-|hypothetical-protein
MPNYATTRLTLAGPQSELDRFVSECVRVQRDDPKGLPALDLDALVPMPPEILATIDNASDEAQQVALAATGHKDWYYWSRASWGTKWNTSAFDGGVIDGMIYDCMFDTAWACPQPALTALAARYPALRGTVVASEQDNDWCLFGAIQDGSYTSATSEFDPQIHLLLRGRFQQGRFPSNSAHALIEGLADARAELETSDASSMSRCAGAIFAALNRRQPSSLIQRLGLERATLDVVRLLDSGVTVLDIRESGLEGAADTAFLLANDRSRTPLDRNLLIAAAAQLRDEALAGYDDEPSPCYFREWIEGWVLPDHDENELWAWAALAMYRPGVLIDMSDVEALKLSVLDYAERLYVQLAAYLSNGRPEQGVSVPSLGRAAA
>NZ_CP019322.1|WP_076641496.1|1376733_1377891_-|hypothetical-protein
MPTCASCASSRLILTGPRLELERFWRECIRVQREDSAGLASLDFEALVPMPLEIVATIRDVSDEALQAALAATGYEDWHDWSVAHWGTEDNVHTYSGRLIGDTIFDCVFQTSWSAPEPVLEVLAARYPGLSGAVLASELLLGECLIGEIRNGAFCSVRAACDRQVDMLINAFDEPGRIGELSVHALIEAIGSPLPGRAGGASASVPMRLTDILAALTRRTSRRLARTLWFERNALDLAAQLADGASARDLRENALAQADQAAGDVVCLLTDGRMRTQLDRKIVEMVTICLCTEAMWADADLGVLPLCRPLVEHAVLTFRSEDELWAWAALAMYRPGLILDLSDADTVKQGILDYAERLHAQLAAYLSDDRREQGVGVPSLGRAAA
>NZ_CP019322.1|WP_076641495.1|1376190_1376730_+|hypothetical-protein
MFALIGTVLAAAEYVLESVGAVQLRLVLVVGVSLSMGLLPPWANLMLAWVLVLRYLPLAVRWRGLWREERWSHRAAREAAAELTDDLVWARRRIAELEWQLARAGDLATSRSGPVPDPLYHSLGLHPGSPDWLVVAARRAFRARLHPDRHPRHRQQAHERFTRAEAQFDLIYARRGIET
>NZ_CP019322.1|WP_076641505.1|1385375_1386275_-|nucleotide-binding-protein
MSDVSDIFTQINNAVLDLQGSQPQTFERPLKILSRLLHSSDLEKFNGDLIAKADYDGFIAESEKTGDSMSGSHQLVWPDDPESVLGLGIQLIDKMAADPGFAIDFCHYYFYSGSKIIAGIHAATRQFIIPFVRDYKAYVTSRGSIQPRLIMPKSNKIFIVHGHDGEARETVARFLGNIGFDPVILHEQPNRGRTIIEKVEANSDVGFAVVLLTPDDEGCVKGGTPEPRARQNVLLELGYFIGLLKRENVCALKRGQVDIPSDFAGVVWETMDAANGWKQALARELQAAGYEVDWNKVMR
>NZ_CP019322.1|WP_076641506.1|1386267_1386558_-|hypothetical-protein
MIKVKGLDKLTRDLDQAQKALSQLEDELGTVSFNPNDPASIESAIQHAEALVDERLGEYSLNPIIGPLAEQMKAAYRDGIVGKAAEARLGSEANDE
>NZ_CP019322.1|WP_076641507.1|1386580_1387990_-|hypothetical-protein
MDISKTRIDNLVEHPSESLNVEIKTWIDLSSEHGLAKLVRAAIALRNRNGGYFIVGFDDKTLLPDTSTRPTDVRTAFHIDKIQATVSRFASIPFEIEIGYANRDGHEYPVIAVPSGVTVPVASKSDLQNPSDAKRLLLRRGDVYFRTLNSSGIASTSAARPEDWAEIISICFENREGDIGRFLRRQLADDGLVRFIAAAQGVLASNVPPPTTLDRAHAILTSGKQFLKEALVDRGDLTAAQKKLTELGSYSTAMVVNPARNVSDSDQAFFNTISSSNPNYTGWPVWLDSRGFRDQKCAPYKNRKGWQALIIAEHSSFPHFDFYRIDAKGEFFLHRVLQDDVSEKVPAGAFLDPIIVILRVAEIIAVGIAFARALGSPDDAMLGFCFEWNGLRGRELEAWGNAGAYFSPGRKAYDDSVLTCVEIPMTTPLPAIAPYVGQAISDLFSAFDGFVISNPVVETWVDKLLTRRL
>NZ_CP019322.1|WP_076641508.1|1388101_1388539_-|hypothetical-protein
MPIRPENRFFYPIDWAQLSNVIRFARAKGCCEGCGRPHGQLVFHLGDGRWWDAGAQTWRSGRGCPLKLAPLECLPAGTVIETTRVYLACAHLDHDPGNNDPKNLRALCQRCHILHDRPEHLRQRWFTYRHRKALGDLFLGPYPTR
>NZ_CP019322.1|WP_076644365.1|1388543_1389125_-|recombinase-family-protein
MLVGYARVSTQDQNLDLQRDALTKAGCERIFEEKKSGKAGTKRPEFEAALAYLRPTDVLVVWKLDRLGRSLVEMMRTIDGLRVKEIHFRSLTEQFDSATAHGRFALQMHGAMAEYFLDLNRERTMEGLKAAVARGRKGGRPKKLGEADLEVGQALLAAGNISIAAIAKRLGVSRFTFYQYFPQARARSQQAKG
>NZ_CP019322.1|WP_076641509.1|1389796_1390000_-|hypothetical-protein
MKTLAATVTALLLLSAAPALAMSCCGGSKGKAPMCGKGGMAMNHAGMKGKKGGCCCEGMAGGMSKRG
>NZ_CP019322.1|WP_076641510.1|1390214_1390451_+|hypothetical-protein
MNRILAALSLAGVCLAPVAASAQYYEYGPPRHHHRHEHIEIERHGDHDHVRVRRHHGDHDHVEERVIERRHHHHDFDD
>NZ_CP019322.1|WP_155773717.1|1390511_1390685_+|hypothetical-protein
MVPPVMVVAHVMAMVMVPHVMMVVMPLHVVMVAAMMMVLHLDHGVRRADGTRQDWGG
>NZ_CP019322.1|WP_081397078.1|1391063_1391381_+|hypothetical-protein
MSTRVLSVLSTIILAMTLQFGTAQAAPLLAGSRSTEQAGTLLQHVQHWGHHHHRRHHHHGWRHHHHGWGHHHHHWRPRHHHHWGHHHHGWGHHHHHHHRRHHHHF
>NZ_CP019322.1|WP_076641513.1|1391448_1391685_-|hypothetical-protein
MKSILPILVAASALILAPAAAMAQHVHVGPGGVSVHGDGHGHGHRHEHVERHDEHHHVERHHDHDGGHEHVTVEKHRH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019322_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019322_2

2462304-2462395

Orphan

Consensus_repeat	Method
TTTTCCGAAAGCCGGCGACCACCTTTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019322_2

>merge|NZ_CP019322|2|2462304-2462395|CRISPRCasFinder
TTTTCCGAAAGCCGGCGACCACCTTTCGGGATGATGCTCTTCGCTTTCGTTCTCGCATCATCTTTTTTCCGAAAGCCGGCGGCCACCTTTCG

>NZ_CP019322|2|2|2462304-2462395|CRISPRCasFinder
TTTTCCGAAAGCCGGCGACCACCTTTCG	GGATGATGCTCTTCGCTTTCGTTCTCGCATCATCTT
TTTTCCGAAAGCCGGCGGCCACCTTTCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019322.1\|WP_076642121.1\|2452927_2453752_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187632
NZ_CP019322.1\|WP_003599081.1\|2465615_2465957_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076642122.1\|2453754_2454669_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_CP019322.1\|WP_076642128.1\|2466399_2466768_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076644412.1\|2457764_2459573_-\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|224720
NZ_CP019322.1\|WP_003599086.1\|2466870_2467080_-\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP019322.1\|WP_003599094.1\|2474305_2474632_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_003599068.1\|2459822_2460017_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076642124.1\|2456126_2456645_-\|DUF2721-domain-containing-protein	unknown	unknown	gnl\|CDD\|378544
NZ_CP019322.1\|WP_076642126.1\|2462405_2463659_-\|ATPase	unknown	unknown	gnl\|CDD\|237425
NZ_CP019322.1\|WP_003599063.1\|2456660_2456990_-\|membrane-protein	unknown	unknown	gnl\|CDD\|226461
NZ_CP019322.1\|WP_076642127.1\|2463956_2465357_+\|acyl--CoA-ligase	unknown	unknown	gnl\|CDD\|223395
NZ_CP019322.1\|WP_076642129.1\|2467456_2471047_-\|transcription-repair-coupling-factor	unknown	unknown	gnl\|CDD\|224118
NZ_CP019322.1\|WP_076642123.1\|2454665_2456177_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NZ_CP019322.1\|WP_076642131.1\|2471748_2473938_+\|ATP-dependent-DNA-helicase-RecG	unknown	unknown	gnl\|CDD\|236794
NZ_CP019322.1\|WP_012255296.1\|2466023_2466221_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019322.1\|WP_076642130.1\|2471260_2471557_-\|succinate-dehydrogenase-assembly-factor-2	unknown	unknown	gnl\|CDD\|225489
NZ_CP019322.1\|WP_012255300.1\|2461842_2462205_-\|response-regulator	unknown	unknown	gnl\|CDD\|381145
NZ_CP019322.1\|WP_015824283.1\|2456994_2457768_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133022
NZ_CP019322.1\|WP_076642125.1\|2460155_2461787_+\|acyl-CoA-synthetase	unknown	unknown	gnl\|CDD\|236169

Protein	Function_ID	Function_description	E-value
NZ_CP019322.1\|WP_076642121.1\|2452927_2453752_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.76396e-61
NZ_CP019322.1\|WP_076642122.1\|2453754_2454669_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	6.15597e-58
NZ_CP019322.1\|WP_012255300.1\|2461842_2462205_-\|response-regulator	gnl\|CDD\|381145	cd18161, REC_hyHK_blue-like, phosphoacceptor receiver (REC) domain of hybrid sensor histidine kinase/response regulators similar to Pseudomonas savastanoi blue-light-activated histidine kinase. Typically, two-component regulatory systems (TCSs) consist of a sensor (histidine kinase) that responds to specific input(s) by modifying the output of a cognate response regulator (RR). TCSs allow organisms to sense and respond to changes in environmental conditions. Hybrid sensor histidine kinase (HK)/response regulators contain all the elements of a classical TCS in a single polypeptide chain. Pseudomonas savastanoi blue-light-activated histidine kinase is a photosensitive HK and RR that is involved in increased bacterial virulence upon exposure to light. RRs share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.86603e-21
NZ_CP019322.1\|WP_003599086.1\|2466870_2467080_-\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	4.06042e-32
NZ_CP019322.1\|WP_076642124.1\|2456126_2456645_-\|DUF2721-domain-containing-protein	gnl\|CDD\|378544	pfam11026, DUF2721, Protein of unknown function (DUF2721). This family is conserved in bacteria. The function is not known.	1.23257e-22
NZ_CP019322.1\|WP_076642126.1\|2462405_2463659_-\|ATPase	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.96727e-88
NZ_CP019322.1\|WP_003599063.1\|2456660_2456990_-\|membrane-protein	gnl\|CDD\|226461	COG3952, COG3952, Predicted membrane protein [Function unknown].	5.18556e-27
NZ_CP019322.1\|WP_076642127.1\|2463956_2465357_+\|acyl--CoA-ligase	gnl\|CDD\|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.71094e-20
NZ_CP019322.1\|WP_076642129.1\|2467456_2471047_-\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_CP019322.1\|WP_076642123.1\|2454665_2456177_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.89975e-93
NZ_CP019322.1\|WP_076642131.1\|2471748_2473938_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP019322.1\|WP_076642130.1\|2471260_2471557_-\|succinate-dehydrogenase-assembly-factor-2	gnl\|CDD\|225489	COG2938, COG2938, Uncharacterized conserved protein [Function unknown].	3.78181e-28
NZ_CP019322.1\|WP_076644412.1\|2457764_2459573_-\|glycosyltransferase-family-39-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	3.27144e-43
NZ_CP019322.1\|WP_015824283.1\|2456994_2457768_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	1.71365e-48
NZ_CP019322.1\|WP_076642125.1\|2460155_2461787_+\|acyl-CoA-synthetase	gnl\|CDD\|236169	PRK08162, PRK08162, acyl-CoA synthetase; Validated.	0

>NZ_CP019322.1|WP_012255300.1|2461842_2462205_-|response-regulator
MADKRTVLVVEDEEMLLSAVTMEFEDAGFAVLSAGTAEEAYGLLQGAGRVDLLFTDIRLPGQLDGWDLAERARVLHPALPVIYVTGYSAEQPRQVSESVLVMKPYRMTAIMSAAQQLGVE
>NZ_CP019322.1|WP_076642125.1|2460155_2461787_+|acyl-CoA-synthetase
MVCTTIYDRDLDPNPANFQPLTPLTYLDRAARTFPDRVAVIHGPLRRSYADLYARCRRLAAALAARGIGRGDTVAVLLANTPAMIECHYGVPMTGAVLNTLNTRLDAGALAFCLDHGEAKVFIVDREFARIGREALDKAGVSPLVIDYDDPEFTGDSAPVGETDYEDFLAAGDPDFDWAMPGDEWDAISLNYTSGTTGDPKGVVYHHRGAALLSLGNVITAGLPQHAVYLWTLPMFHCNGWCFPWTLSIVAGTHVCLRQVRAPAMYAALAEHGVTHLSGAPIVMSTLLNVPEAQKRPLPRRVHFLTAAAPPPEAVLAAMGEAGFDVTHLYGLTETYGPAVVNAWHEDWDALSRDEQARKKARQGVRYPVLEGLDVRDPETMESLPADGTSLGEVMFRGNVVMRGYLKNPASTEAAFKGGWFRSGDLGVKHPDGYIQLKDRSKDIIISGGENISSIEVEDALFKHPAVAAAAVVAKPDAKWGETPCAFIELKEGREATSEELVAWCRERLAPYKLPRHVVFGELPKTSTGKVQKFVLREKAREE
>NZ_CP019322.1|WP_003599068.1|2459822_2460017_+|hypothetical-protein
MANNSANPYTLEIEACERPAGHFTWAIRRNGKLFQRADRVQTTEEAAERSGLAALEKLLSGRER
>NZ_CP019322.1|WP_076644412.1|2457764_2459573_-|glycosyltransferase-family-39-protein
MTRLGVAPAALSRAEGGWPLDGALRLGDRVLSFGAASHLRACLLLLLIGLASFLPGLASLQPMDRDEPRFAQASKQMLETGDLVDIRFQAEARHKKPVGIYWAQAAAVAAGEALGVPQARTQIGLYRIPSLLGALAAILLTYWAGLAPLDRRRALLAAALFSACIMLSAEARLAKTDALLTACSIAVFGALARAWLGRARLERRRGPASLGTALVFWLGLALGILVKGPMVPLFAGLAAFVLCLREGSARWLLDLRPRLGLLITLAVVAPWFLAIAWKSGGAFFGEAVGRDMLGKVGTGAEKHWGPPGAYALAFFATFWPGAAFAALSLPFAWARRGEEAVALLLAWIVPMWLIFEAVPTKLPHYVLPLMPAVAILTVLALSRGALDPRRPGARWVAGLVVLIPVGLTLGVSLAAWRLDHVLPLAALPLLLAACLLAGLAWAAFARGAREGAGQRAGQETRQETGEGALVLAVAASVVLSGAVFGLTQPVLQSLKVSPRLAAIRDALPCEAPRVASLGLREPSLVFTVGTDLAMLNSGAETIAFLREGGCRLVLVEDRFAAEFTAAEGGQPLSPVGRVTGFNINGGKPVGVSAYAALPGSTP
>NZ_CP019322.1|WP_015824283.1|2456994_2457768_-|glycosyltransferase-family-2-protein
MSTTTQSVDPVFRPPRLSVVVPVKNEAGNIEALVAEIGHACQTLAPFEVIYVDDGSTDATLATLRGLQAKQPWLRVVRHDRGGGQSGAVRSGVLRARAPVIATLDGDGQNDPSFIPVLYAALEQAGPTVGLAQGQRIGRKGAWKQFQSRIANGVRGKILKDATRDTGCGLKVFRREVYLTLPYFDALHRFMPALVTREGFGVVHRDVVDRPRFTGHSNYGMFDRLWVGILDLAGVWWLIRRRRPAPRAEEIPHSESR
>NZ_CP019322.1|WP_003599063.1|2456660_2456990_-|membrane-protein
MLIQLAEDLPAYFYDVFVTRFDFWLVFGIGAQLVFGSRFILQWIASERAGKSVMPLSFWFLSIIGGLMTLVYGFVRREPVIIIGQGLSTFIYLRNLALIFRERRRARRA
>NZ_CP019322.1|WP_076642124.1|2456126_2456645_-|DUF2721-domain-containing-protein
MFQTATGDPESIAHIIQVALAPAFLLSALATLLNVFSPRLGRVADKVDALSASLPGADEAARATLARRLAYLRRRSLLLDLAVVLASLGGVMTGAAVLTLFVGALRDASAASVLFACFGLALSCTILAILAFLAEILLAGRGIRLEVERKQDRPRSSGFRKGEPFRGSRAEP
>NZ_CP019322.1|WP_076642123.1|2454665_2456177_+|NAD(P)/FAD-dependent-oxidoreductase
MSEAPLDLVIVGAGFSGLAMAIRARQAGFDRLLVLEKAAGVGGTWRENTYPGAACDVPSQLYSLSFAPKSDWSRLFAPQPEIEAYLEGLVAAHGLAPFLRLETCVKRAVFDAAAGLWRVETDRGVVSARVLVGAMGALHHPALPRLPGLEQFSGKAFHSAAWDHSCDLTAQRVGVIGTGASAVQFVPEIVGRVAHLTQFQRSAPWILPRGDRPTGRGFRRLMRIAPLRRLHRASLFWRREVAALAGFTRVSRVTALAEAWSRRHLAASIADPALRRQLTPDYRLGCKRVLLSDDYYPALAQPHASLVTAPIREVLPHGIVTADGAEHPLDVLIFATGFAPGGSVVRTEVIGRDGLSLLQAWKQGADAFRGVSVAGFPNFFLLLGPNTGLGHNSVLLMVEAQVAHVLGALKRLRDWPGGVLEVRPEAQARFREEVDARMRDSIWTQGGCGSWYLDRAGRNRTLWPGTVGDYVRGTEQMRAEDYDVVGSSGLRPGPAKGLALSKP
>NZ_CP019322.1|WP_076642122.1|2453754_2454669_+|alpha/beta-hydrolase
MASLRAHLYDLTIRLAVKGRLGGTHDVYAIRRAFEGARFPTPAGVAFTPGEVGGVPGEWAEAAGADGERPTLLYCHGGGFIACSAQLYRPVTGRFARAGFRVFTPDYRLAPEHPFPAAVEDCTGVWATLAEAGPAVVAGDSAGGSLALTTIIEARRLGLTPPVAAALFSPATDLIGRSASFRTNGRRDAMFRPEALMRLVPAYLAGADPADPRASPIEADFSGFPPLLIHVGLREILRDDSLRLAEKAKAAGVPVELTVFPVVTHAWQLAESFLPEARRSLDEAATFLHRALKAPPHPEAEVAA
>NZ_CP019322.1|WP_076642121.1|2452927_2453752_+|SDR-family-NAD(P)-dependent-oxidoreductase
MAQRFVLQGRTALVTGAASGIGAALSLALAGRGCALALADRDAQGLAETARAARAAGVTVSEHVLDLADREALLALPEAVRARHGGLHLLVNNAGVALGGRFEDTDPADIDWLMDVNLHAVMRLTHACLPLLRAQAQAQIVNLSSVFGIIAPAGQAAYAASKFAVRGFTEALRHEVEGTGLGVTLVHPGGVATAIARNARRPRTMDPHEAAEAHLAFERLLTMSPAKAAAAILRGIETRAPRVVIGADARRALLIQRLMPVRYWSLIRRAVRDT
>NZ_CP019322.1|WP_076642126.1|2462405_2463659_-|ATPase
MLELLRRLWEVENLSPHGICLLWRPELIWTHVVSDSLIAFAYFSIPVGLAYFVSRRRDVVFGWMFWSFAVFITACGATHLMAIWTLWVPDYGLEAAVKLITGMASIGTAVALWVLIPKALTLPSPTQLRQANEALQARIAERDAALAALEAANAERARAEEALRQSQKMEAIGQLTGGVAHDFNNLLNVVLLNLDRVERGLPEASPLRTRLRDAVKGAERAATMTHKLLAFARRQPLSPVSTDVNAQIASFAEFLRGTIGPRIRLETDLAPNLPRVRIDPNQFESAILNLAVNARDAMPEGGTLTLATRPLPEGDGFAVEVSDTGAGMAPEVEARAFEPFFTTKPLGQGTGLGLSQVFGFAQQSGGSAAFVRDGRPGTTVRLSFPAQAPAVSRPAVRQAPVTEQGFAPLLPPVAVAG
>NZ_CP019322.1|WP_076642127.1|2463956_2465357_+|acyl--CoA-ligase
MSAQRAITQVEASQRAVQGALKGASQGTPDAASHETPADAPLRRISLGSLLSATARRHPDRIAVVDPADKPDWSDRPAITWTYAAAAEIVERLARGLRSWRLPPGSRIGLCLPGSAESALAILAVEAAGHVACLLPVSWDEDRLLAAAQNVALSAVLTQARLGSAAPAERLCAVAARYFGLRYLAAFGPDVPDGVINLDRFVLDGPAGEPAGPAPAAAGIVSFIGGDPEQPVYRSGESVVAAAAAHLVAMRVAPAERILSLIGPHDLRGLATGLAAALVAGATLETLPLFDGAAFATAMRRPGPTHLVAPAFLEKNLAGRDLPTDLRSVALVHRAPVRFPSRSRAVDRPQGLRLEMVIDTVAFDETAILSGRRGTTGDLSLVLGKPERLALPAALMSMKRGADDRLAFRGQACTVTPLQRGNRQAIPSGVWQETPYAPVLFAGFATAIEVVEPSDSASSPKIFAPA
>NZ_CP019322.1|WP_003599081.1|2465615_2465957_+|hypothetical-protein
MGALQQVLVVDDGRRAVDRSLAADLAGLGYASVTASIEAADDVLAVIARPAAILLQLSSSTNPHLAALADRLRARMRAGGIPVIEMDDAGPRPGAPVDLKSRIGPYVLAEPEL
>NZ_CP019322.1|WP_012255296.1|2466023_2466221_-|hypothetical-protein
MFHKFKIGQRVRRAQSSPTDERLGFGTISEVVRLMPDDPTGEPSYRIRSGSAERAVRESEIIAAA
>NZ_CP019322.1|WP_076642128.1|2466399_2466768_-|hypothetical-protein
MSFTKQNSFDDRRQDSASSREAMLARFRARPSNDDPAVQARQAERRAVAVARDERVKERETQRRLDAERLAAIAAAEREAEVARKAAEIEAAAERAREAQAKQKEERDARYAARKAKIKLRR
>NZ_CP019322.1|WP_003599086.1|2466870_2467080_-|cold-shock-protein
MSIGTVKWFNEQKGFGFIQPEDGSKDVFVHISAVERAGLRGLTEGQKVSYEMETDRRSGKQSAGQLQVA
>NZ_CP019322.1|WP_076642129.1|2467456_2471047_-|transcription-repair-coupling-factor
MAKPQPKPPAPKPQTARFALPKSAPLTKALDAIKRGDSPTLASVPDGFDALVAADLARALSGSFEGPAVLVHVARDSGRSNAFQNALKFVAPEIEAMSVPAWDCQPYDRVSPNGAIAAQRMTALSRLTRSRSSEEKPRILCTTVNALVQRVPPRSRVAVETFSAAIGNVVPMDKVVAWVEANGFLRTGTVRDTGEYAVRGGILDLSPPGLPNPIRLDFFGDTLESIRAFDPETQRTVGSLRSLDLVPMSEVQLTTETIRRFRQGYLSSFGAATRDDRLYETVSEGRRYAGLEHWMPLFYDGLDTLFDYLGDVPMLFDPQVEEAAAERLALIQDYFQAREAALKNPQSGVAPYKPLPPRALYLTPNEWKSKVESGTVVRLTPFATPDSDERAVIDCGAKAGRSFAPERADDAASVFDAAVAHIRDLQASGHHVILGSWSEGSRDRLCGVLTDHGLKKPTVINTFAAVNALKRGTDVAVAVWGLESGFTLDRLAVVAEGDILGDRLVRQKRKSKRPQDIILEVQALQPGDLVVHADHGIGRFVTLKTVTAAGAPHDCLELQYAGGLLLLPVENIELLTRYGSEDSEVALDRLGGGAWQARKAKMKRRILEMAGDLIKIAAARFVKSAPSLKAPEGLYEEFAARFAFQETEDQANAIDAVLDDLNAGRPMDRLVCGDVGFGKTEVALRAAFAAAISGKQVAVVVPTTLLARQHFRTFAERFKGLPINVAQLSRFVSAGEQRQNRAGLADGTVDIVVGTHALLAKNVAFKDLGLIIVDEEQHFGVAHKERLKALQADVHVLTLSATPIPRTLQLAMTGVRELSIIATPPMDRLAVRTFVTPFDPLLVREALLRERYRGGQSFYVAPRIEDLAEVKRFLDTEMPETTVAVAHGQMAAGQLEDVMTAFYEGKYDVLLSTTIVESGLDIPTANTLIVHRADMFGLAALYQLRGRVGRSKARAYALFTTPANRQLTAQAEQRLKVLQSLDTLGAGFQLASHDLDIRGAGNLLGDAQSGHIKEVGYELYQQMLEDAVTALKAGIEEPVEEAWSPTIALGAPVTIPEDYVEDLTVRLGLYRRLSTLENDAEMESFGAELIDRFGPLPPEVEQLLKIVTIKILCRDANVEKVEAGPKGVVVHFRNRSFANPQGLAAMVVEQGSFAKVRPDMSVVFIRELDGIPRRLKETTQILRGLVTIAKRAKKAA
>NZ_CP019322.1|WP_076642130.1|2471260_2471557_-|succinate-dehydrogenase-assembly-factor-2
MSGTTRTSADLDPRRRRTLFRAWHRGIREMDLIMGRFADSEIGALSEEELTQFEALIEVPDRDLFRWLTGEDETPDNYDTAVYRRLKAFHRHDAPIHS
>NZ_CP019322.1|WP_076642131.1|2471748_2473938_+|ATP-dependent-DNA-helicase-RecG
MTSDTSQTLGHPADAAPPRSGGDVAPGLRPSLLDPLFAPARGLPGVGPKIAPLIEKLLGSEERPARVADLLFHLPQSGVARPLCGSIRDAPTGEPVTLGVTVVAHRPPMLGKRAFRVLVEDGTGDISLVFFGMPRGRIEKMLPLGSHRYVSGRIDLWDGTRQMVHPSRILDQEGLASLPAVEPIYGATEGLTSRVISRIVHGALDRLPVLPEWQDASYLARNRFPPFAEALRIEHRPEEAPPPPVEGQAPPASPARKRLAYDELLASQLALALVRARQRRKPGRVNAGDGHLKERVEAALPFALTGAQARAVEEIRADMAAERRMLRLLQGDVGSGKTAVALLAMASAVEAGRQAALMAPTEILARQHYERLVPLAGAMRLRLLTGRDRAAERRATLADLAAGEIDIVVGTHALFQESVAFRDLGLAVVDEQHRFGVHQRLALGAKGEAVDILVMTATPIPRTLALTFFGDMDVSVLDEKPAGRQPIKTITVPVERIDEVVGGLHRALAAGDRVYWICPLVAESEYVDLAAAAERFEDLQKHFGDAVGLIHGKMPGPEKDAAMEAFSAGRTRVLVSTTVVEVGVDVPEATIMVIEHAERFGLAQLHQLRGRVGRGSKASSCLLLYRGPLGQVAKARLEMMRSSEDGFRIAEEDLRLRGEGEVLGTRQSGAAAFRLARLETDGDLLEAARDDARLIVERDPRLQSERGRALRVLLYLFEREAAIRLIGAG
>NZ_CP019322.1|WP_003599094.1|2474305_2474632_+|hypothetical-protein
MSIAPFQRLPGSSENWGADTLSIEPWLMPISDRETRDETSTDALVNAVRQSSRRLWIAANALCAGLALLVTVQIASDWSSPVARPAATHQVADATPPTLPVEKASLQH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

651675 : 676669

Burkholderia_phage(20.0%)

capsid,head,protease,terminase,portal,integrase,tRNA

attL 651572:651587|attR 661514:661529

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
651572:651587	attL	NA	NA	NA	NA
WP_155773826.1\|651675_652668_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_076640772.1\|652820_653906_+\|integrase	site-specific integrase	I6NSG1	Burkholderia_phage	9.4e-119	59.6
WP_076640774.1\|654027_654897_+	hypothetical protein	NA	NA	NA	NA
WP_155773692.1\|655199_656498_+	hypothetical protein	NA	NA	NA	NA
WP_076640776.1\|656570_657452_+	DNA adenine methylase	A0A2K9R7J9	Dishui_lake_phycodnavirus	1.3e-17	27.0
WP_076644330.1\|657578_657839_-	Pyocin activator protein PrtN	I6NSR8	Burkholderia_phage	6.0e-24	67.1
WP_076640778.1\|657847_658288_-	hypothetical protein	NA	NA	NA	NA
WP_076644331.1\|658287_658494_-	hypothetical protein	NA	NA	NA	NA
WP_076640779.1\|658561_658879_-	hypothetical protein	NA	NA	NA	NA
WP_155773693.1\|658875_659094_-	hypothetical protein	NA	NA	NA	NA
WP_076640782.1\|659090_659399_-	hypothetical protein	NA	NA	NA	NA
WP_076640783.1\|659401_660526_-	DNA polymerase III subunit beta	A0A0A8IL17	Aurantimonas_phage	2.2e-70	44.1
WP_076640785.1\|660633_661701_-	DUF2303 family protein	A0A0A8IL76	Aurantimonas_phage	3.1e-58	38.7
661514:661529	attR	NA	NA	NA	NA
WP_076640787.1\|661763_662087_-	hypothetical protein	NA	NA	NA	NA
WP_155773694.1\|662145_662373_-	hypothetical protein	NA	NA	NA	NA
WP_081397064.1\|663147_663627_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076640794.1\|663632_663893_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_155773695.1\|663898_664153_-	hypothetical protein	NA	NA	NA	NA
WP_076640798.1\|664335_664833_+	hypothetical protein	NA	NA	NA	NA
WP_076640800.1\|664829_665177_+	hypothetical protein	NA	NA	NA	NA
WP_076644332.1\|665304_666453_+	hypothetical protein	I3UM61	Rhodobacter_phage	1.8e-40	39.7
WP_155773696.1\|666581_667421_-	hypothetical protein	NA	NA	NA	NA
WP_076640801.1\|667525_669022_+	hypothetical protein	A0A221SAP5	Ralstonia_phage	1.2e-76	35.9
WP_081397065.1\|669468_670125_+	hypothetical protein	NA	NA	NA	NA
WP_076640807.1\|670768_671395_+\|terminase	P27 family phage terminase small subunit	NA	NA	NA	NA
WP_076644333.1\|671696_673148_+\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	5.7e-71	33.4
WP_076640809.1\|673153_674431_+\|portal	phage portal protein	Q6JIM9	Burkholderia_virus	1.4e-97	46.5
WP_076640811.1\|674438_675332_+\|head,protease	HK97 family phage prohead protease	NA	NA	NA	NA
WP_076644334.1\|675349_676669_+\|capsid	phage major capsid protein	A0A2H4JD98	uncultured_Caudovirales_phage	3.6e-88	48.7

DBSCAN-SWA_2

2177491 : 2238834

Bacillus_virus(25.0%)

integrase,protease,transposase

attL 2222557:2222616|attR 2238844:2240093

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114385288.1\|2177491_2178633_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_056114755.1\|2179182_2180550_-	hypothetical protein	NA	NA	NA	NA
WP_081397095.1\|2181291_2182530_+	GGDEF domain-containing protein	G3MA91	Bacillus_virus	1.1e-17	36.0
WP_076641965.1\|2182827_2183088_+	hypothetical protein	NA	NA	NA	NA
WP_076641967.1\|2183868_2185425_+	pilus assembly protein	NA	NA	NA	NA
WP_076641968.1\|2185421_2186003_+	pilus assembly protein	NA	NA	NA	NA
WP_081397184.1\|2185696_2186575_+	hypothetical protein	NA	NA	NA	NA
WP_155773745.1\|2186678_2187776_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-51	42.0
WP_076641970.1\|2188002_2190390_-	EAL domain-containing protein	NA	NA	NA	NA
WP_056114778.1\|2190707_2191181_-	response regulator	NA	NA	NA	NA
WP_076644401.1\|2191210_2191663_-	BLUF domain-containing protein	NA	NA	NA	NA
WP_076641971.1\|2191886_2192360_+	PAS domain-containing protein	NA	NA	NA	NA
WP_076641972.1\|2192471_2193227_-	EAL domain-containing protein	NA	NA	NA	NA
WP_076641973.1\|2193896_2196230_-	TonB-dependent receptor	NA	NA	NA	NA
WP_076641974.1\|2196333_2197707_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_076641976.1\|2199022_2199808_+	hypothetical protein	NA	NA	NA	NA
WP_155773830.1\|2199870_2201994_+	TonB-dependent receptor	NA	NA	NA	NA
WP_076641977.1\|2201994_2202879_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_076641978.1\|2202875_2203856_+	iron ABC transporter permease	NA	NA	NA	NA
WP_076641979.1\|2203852_2204605_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	3.4e-11	28.2
WP_155773746.1\|2205415_2205814_-	cupin	NA	NA	NA	NA
WP_081397096.1\|2206086_2207601_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_081397185.1\|2207621_2208269_+	response regulator transcription factor	NA	NA	NA	NA
WP_155773747.1\|2209409_2209655_-	hypothetical protein	NA	NA	NA	NA
WP_076641982.1\|2209769_2210177_-	helix-turn-helix transcriptional regulator	A0A223W054	Agrobacterium_phage	6.6e-17	39.2
WP_155773748.1\|2210365_2210704_-	hypothetical protein	NA	NA	NA	NA
WP_076641986.1\|2212590_2219619_+	heme peroxidase	NA	NA	NA	NA
WP_076641987.1\|2219890_2220250_-	hypothetical protein	NA	NA	NA	NA
WP_076641988.1\|2220732_2221800_-	DNA polymerase IV	NA	NA	NA	NA
2222557:2222616	attL	NA	NA	NA	NA
WP_114385288.1\|2222625_2223766_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_081397099.1\|2223907_2224054_-	DUF4113 domain-containing protein	NA	NA	NA	NA
WP_076641989.1\|2224167_2225058_-	3'-5' exonuclease	M1I9H3	Bacillus_virus	1.4e-06	34.7
WP_076641990.1\|2225292_2225493_+	hypothetical protein	NA	NA	NA	NA
WP_076641991.1\|2225824_2227480_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_076641992.1\|2227802_2229212_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_015824465.1\|2229486_2230461_+	2-hydroxyacid dehydrogenase	M1HUT5	Acanthocystis_turfacea_Chlorella_virus	1.2e-11	28.7
WP_076641993.1\|2230457_2231357_+\|protease	AprI/Inh family metalloprotease inhibitor	NA	NA	NA	NA
WP_076641994.1\|2231426_2232179_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_076641995.1\|2232232_2232481_-	hypothetical protein	NA	NA	NA	NA
WP_076641996.1\|2232656_2233610_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_076641997.1\|2233637_2234648_-	2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	1.5e-65	43.3
WP_076641998.1\|2235323_2235677_+	hypothetical protein	NA	NA	NA	NA
WP_081397100.1\|2235561_2237313_+	replicative DNA helicase	A0A076G7E6	Sinorhizobium_phage	4.0e-55	34.3
WP_076642001.1\|2237309_2237657_+	DUF1376 domain-containing protein	NA	NA	NA	NA
WP_114385288.1\|2237692_2238834_-\|transposase	IS3 family transposase	NA	NA	NA	NA
2238844:2240093	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2785619 : 2834981

Acanthamoeba_polyphaga_moumouvirus(16.67%)

protease,transposase,tail,portal,integrase,tRNA

attL 2808520:2808568|attR 2832569:2832617

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003599551.1\|2785619_2786594_+\|protease	serine protease	NA	NA	NA	NA
WP_076642286.1\|2786632_2788255_-	calcium-binding protein	NA	NA	NA	NA
WP_076642287.1\|2788547_2789972_+\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_076642288.1\|2790050_2791187_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SJE0	Klosneuvirus	1.4e-93	44.5
WP_076642289.1\|2791313_2792348_-	NAD-dependent epimerase/dehydratase family protein	K7Y9E1	Megavirus	1.3e-40	34.7
WP_076642290.1\|2792347_2793223_-	SDR family oxidoreductase	A0A2P1ELT6	Moumouvirus	1.6e-28	31.4
WP_081397104.1\|2793227_2793908_-	hypothetical protein	NA	NA	NA	NA
WP_076642291.1\|2794483_2795479_+	SDR family NAD(P)-dependent oxidoreductase	L7RCI0	Acanthamoeba_polyphaga_moumouvirus	4.0e-23	26.2
WP_076642292.1\|2795489_2796206_+	NTP transferase domain-containing protein	NA	NA	NA	NA
WP_081397105.1\|2796260_2797295_-	NAD(P)-dependent oxidoreductase	L7RCI0	Acanthamoeba_polyphaga_moumouvirus	6.6e-13	26.6
WP_081397106.1\|2797237_2799286_-	glycosyltransferase	NA	NA	NA	NA
WP_076642295.1\|2799267_2800848_-	hypothetical protein	NA	NA	NA	NA
WP_076642296.1\|2800831_2802166_-	glycosyltransferase	NA	NA	NA	NA
WP_081397107.1\|2802169_2803435_-	glycosyltransferase	NA	NA	NA	NA
WP_155773757.1\|2803431_2803866_-	hypothetical protein	NA	NA	NA	NA
WP_081397108.1\|2804315_2804546_-	glycosyltransferase	NA	NA	NA	NA
WP_155773758.1\|2805174_2805336_+	hypothetical protein	NA	NA	NA	NA
WP_076642299.1\|2805335_2807003_+	hypothetical protein	NA	NA	NA	NA
WP_155773759.1\|2807141_2808146_+	hypothetical protein	NA	NA	NA	NA
2808520:2808568	attL	NA	NA	NA	NA
WP_081397109.1\|2808700_2809876_+\|integrase	site-specific integrase	A0A2H4IYX8	uncultured_Caudovirales_phage	7.7e-10	22.7
WP_076642300.1\|2809872_2810562_+	hypothetical protein	NA	NA	NA	NA
WP_076642301.1\|2810666_2810891_+	hypothetical protein	NA	NA	NA	NA
WP_155773760.1\|2811496_2811901_+	hypothetical protein	NA	NA	NA	NA
WP_076642303.1\|2811946_2812462_+	hypothetical protein	NA	NA	NA	NA
WP_155773761.1\|2812787_2813504_+	hypothetical protein	NA	NA	NA	NA
WP_076642305.1\|2813960_2815082_+	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_076642307.1\|2815613_2817203_+\|portal	phage portal protein	A0A0C5AJ48	Bacteriophage	1.1e-96	42.7
WP_081397110.1\|2817199_2818219_+	S49 family peptidase	A0A219YB02	Aeromonas_phage	5.6e-41	41.7
WP_076642309.1\|2818238_2820191_-	DUF3732 domain-containing protein	NA	NA	NA	NA
WP_155773762.1\|2820190_2820679_-	hypothetical protein	NA	NA	NA	NA
WP_155773763.1\|2820678_2821905_-	hypothetical protein	NA	NA	NA	NA
WP_155773764.1\|2822175_2822409_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_076642312.1\|2822419_2822677_+	hypothetical protein	NA	NA	NA	NA
WP_076642313.1\|2822686_2823466_+	hypothetical protein	NA	NA	NA	NA
WP_076642314.1\|2823529_2824171_+	hypothetical protein	NA	NA	NA	NA
WP_155773765.1\|2824170_2824509_+	hypothetical protein	NA	NA	NA	NA
WP_076642316.1\|2824511_2828444_+\|tail	phage tail tape measure protein	M4SQV9	Cyanophage	1.3e-05	48.4
WP_155773766.1\|2828561_2829395_+	hypothetical protein	NA	NA	NA	NA
WP_155773767.1\|2829589_2830567_+	hypothetical protein	NA	NA	NA	NA
WP_076642318.1\|2830572_2831199_+	NADAR family protein	A0A2K9L9C1	Tupanvirus	1.3e-11	31.0
WP_081397112.1\|2831218_2832346_-\|integrase	tyrosine-type recombinase/integrase	F8TUV0	EBPR_podovirus	7.1e-53	37.8
WP_076642320.1\|2833180_2833525_+	hypothetical protein	NA	NA	NA	NA
2832569:2832617	attR	NA	NA	NA	NA
WP_155773768.1\|2833882_2834981_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.2e-52	42.8

DBSCAN-SWA_4

5585516 : 5639067

Paracoccus_phage(26.67%)

capsid,head,protease,portal,tail,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076644268.1\|5585516_5586791_-\|tRNA	CCA tRNA nucleotidyltransferase	A0A2L0UZ92	Agrobacterium_phage	1.1e-36	46.8
WP_012253083.1\|5586787_5587045_-	hypothetical protein	NA	NA	NA	NA
WP_056507274.1\|5587113_5587797_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_076644269.1\|5587793_5588375_-	DUF1285 domain-containing protein	NA	NA	NA	NA
WP_003606720.1\|5588371_5588806_-	PaaI family thioesterase	NA	NA	NA	NA
WP_012253080.1\|5589002_5590013_+	MoxR family ATPase	NA	NA	NA	NA
WP_076644270.1\|5590024_5590939_+	DUF58 domain-containing protein	NA	NA	NA	NA
WP_076644271.1\|5590952_5593790_+	DUF4159 domain-containing protein	NA	NA	NA	NA
WP_076644272.1\|5593980_5596071_+	hypothetical protein	NA	NA	NA	NA
WP_076644273.1\|5596126_5596993_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076644544.1\|5597163_5598066_+	EamA family transporter	NA	NA	NA	NA
WP_155773824.1\|5598221_5601500_+	PAS domain S-box protein	NA	NA	NA	NA
WP_076644275.1\|5601531_5603613_-	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_076644276.1\|5603907_5604792_-	alpha/beta hydrolase	A0A0M3UKI8	Mycobacterium_phage	1.4e-08	33.6
WP_003601905.1\|5605012_5605459_+	hypothetical protein	NA	NA	NA	NA
WP_042508769.1\|5605483_5605765_-	hypothetical protein	NA	NA	NA	NA
WP_003601903.1\|5605944_5606484_+	formaldehyde-activating enzyme	NA	NA	NA	NA
WP_076644545.1\|5606680_5608222_-	class II fumarate hydratase	NA	NA	NA	NA
WP_076644277.1\|5608773_5609376_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	C7F482	Cyanophage	5.0e-05	29.7
WP_076644278.1\|5609375_5609885_-	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	NA	NA	NA	NA
WP_076644279.1\|5609987_5610479_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_015822075.1\|5610465_5610888_+	DUF1772 domain-containing protein	NA	NA	NA	NA
WP_003606625.1\|5611172_5611355_+	CbtB-domain containing protein	NA	NA	NA	NA
WP_076644280.1\|5611385_5612153_+	CbtA family protein	NA	NA	NA	NA
WP_076644281.1\|5612145_5612550_+	DUF1636 domain-containing protein	NA	NA	NA	NA
WP_003606629.1\|5612553_5613588_+	cobalamin biosynthesis protein CobW	NA	NA	NA	NA
WP_076644282.1\|5613584_5614481_+	DUF4349 domain-containing protein	NA	NA	NA	NA
WP_076644283.1\|5617920_5619207_+	precorrin-3B synthase	NA	NA	NA	NA
WP_076644284.1\|5619213_5619846_+	precorrin-8X methylmutase	NA	NA	NA	NA
WP_003602221.1\|5619845_5620643_+	precorrin-2 C(20)-methyltransferase	NA	NA	NA	NA
WP_076644285.1\|5620639_5621401_+	precorrin-3B C(17)-methyltransferase	NA	NA	NA	NA
WP_076644286.1\|5621825_5622254_+	hypothetical protein	NA	NA	NA	NA
WP_076644287.1\|5622216_5623482_+	DNA-packaging protein	A0A1V0DY66	Dinoroseobacter_phage	2.5e-75	42.8
WP_076644288.1\|5623532_5624705_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	1.1e-67	40.8
WP_076644289.1\|5624762_5625233_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	5.6e-28	50.7
WP_076644290.1\|5625265_5626531_+\|capsid	phage major capsid protein	U5P0G9	Shigella_phage	8.2e-82	44.6
WP_003606880.1\|5626537_5627386_-\|protease	trypsin-like serine protease	I6WTR7	Cotesia_sesamiae_Mombasa_bracovirus	2.9e-06	23.4
WP_076644291.1\|5627533_5628289_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_056462181.1\|5628322_5628898_+	hypothetical protein	NA	NA	NA	NA
WP_076644292.1\|5628919_5629261_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_076644293.1\|5629257_5629677_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_076644294.1\|5629706_5630117_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_076644295.1\|5630119_5630446_+	gene transfer agent family protein	NA	NA	NA	NA
WP_076644296.1\|5630442_5630673_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_076644297.1\|5630672_5631299_+\|tail	phage tail tape measure protein	G9JXH3	Shigella_phage	7.3e-07	68.3
WP_155773825.1\|5631356_5631953_+	TIGR02217 family protein	A0A0B5A2K3	Paracoccus_phage	1.3e-42	51.3
WP_076644298.1\|5631963_5632857_+	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	3.0e-62	42.4
WP_076644299.1\|5632864_5633329_+	peptidase P60	A0A1V0DYB6	Dinoroseobacter_phage	1.7e-29	47.5
WP_076644300.1\|5633368_5637277_+	hypothetical protein	A0A0B5A7K5	Paracoccus_phage	2.1e-192	36.1
WP_076644301.1\|5637301_5638384_+	DUF2793 domain-containing protein	A0A0K1LM04	Rhodobacter_phage	1.9e-34	38.5
WP_076644302.1\|5638503_5639067_+	lysozyme	W6E9Q2	Rhizobium_phage	3.1e-25	41.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP019322

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection