CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014487	Bacillus cereus strain FORC021 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP014486	Bacillus cereus strain FORC021 chromosome, complete genome	4 crisprs	cas3,csa3,WYL,RT,DinG,cas14k,Cas14u_CAS-V,c2c9_V-U4,DEDDh	0	2	6	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 41166

Bacillus_phage(48.84%)

terminase,holin,tail,capsid,head,portal

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072770110.1\|1274_1622_-	hypothetical protein	NA	NA	NA	NA
WP_072770111.1\|1942_2260_-	helix-turn-helix transcriptional regulator	B5LPU3	Bacillus_virus	1.4e-51	95.2
WP_072770112.1\|2787_3975_+	hypothetical protein	A0A0S2MVK2	Bacillus_phage	5.0e-73	40.3
WP_088027289.1\|4006_4165_+	complement C1q protein	NA	NA	NA	NA
WP_072770113.1\|4487_4829_-	helix-turn-helix transcriptional regulator	A0A1B0T6A7	Bacillus_phage	1.3e-18	43.9
WP_001231651.1\|5016_5259_+	helix-turn-helix transcriptional regulator	O03906	Lactobacillus_phage	2.4e-06	40.8
WP_072770114.1\|5271_6030_+	phage antirepressor KilAC domain-containing protein	Q6J1W3	Lactobacillus_phage	1.9e-46	44.9
WP_173668931.1\|6146_6284_+	hypothetical protein	A0A1B1P8A8	Bacillus_phage	1.6e-15	90.9
WP_072770115.1\|6485_8018_+	hypothetical protein	A0A2I7SC81	Paenibacillus_phage	4.0e-83	39.3
WP_072770116.1\|8010_8952_+	recombinase RecT	A0A0C5AEC1	Paenibacillus_phage	3.4e-48	38.8
WP_072770117.1\|9121_9871_+	DnaD domain protein	A0A1B1P8C4	Bacillus_phage	9.5e-54	56.2
WP_077393204.1\|9854_10613_+	ATP-binding protein	U5PWH5	Bacillus_phage	6.3e-37	39.1
WP_072770119.1\|10625_10817_+	hypothetical protein	A0A1B1P8D7	Bacillus_phage	3.3e-19	73.0
WP_072770120.1\|10813_11080_+	hypothetical protein	W8CYZ5	Bacillus_phage	5.8e-22	56.8
WP_072770121.1\|11095_11413_+	hypothetical protein	A0A0M4R373	Bacillus_phage	3.8e-12	44.8
WP_072770122.1\|11427_11880_+	nucleoside permease	NA	NA	NA	NA
WP_072770123.1\|11876_12284_+	hypothetical protein	A0A1B1P8A6	Bacillus_phage	1.6e-26	69.0
WP_072770124.1\|12292_12436_+	Fur-regulated basic protein FbpA	A0A1B1P8B6	Bacillus_phage	1.5e-16	95.5
WP_072770125.1\|12680_12944_+	glutaredoxin family protein	B5LPN1	Bacillus_virus	1.1e-22	63.2
WP_173668932.1\|12954_13122_+	hypothetical protein	NA	NA	NA	NA
WP_072770126.1\|13135_13642_+	dUTP diphosphatase	M4W9N7	Bacillus_phage	2.4e-16	33.5
WP_173668933.1\|13771_13945_+	hypothetical protein	NA	NA	NA	NA
WP_072770127.1\|14129_14678_+	DNA (cytosine-5-)-methyltransferase	A0A2H4PBE1	Lactobacillus_phage	3.9e-57	56.7
WP_077393205.1\|14565_15063_+	DNA cytosine methyltransferase	A0A218MND0	uncultured_virus	1.8e-24	50.9
WP_072770128.1\|15203_15608_+	hypothetical protein	NA	NA	NA	NA
WP_173668934.1\|15646_15823_+	hypothetical protein	A0A1B1P875	Bacillus_phage	2.9e-22	89.5
WP_072770129.1\|15824_16241_+	RusA family crossover junction endodeoxyribonuclease	S6B1L9	Thermus_phage	5.1e-49	69.6
WP_072770130.1\|16483_16870_+	ArpU family transcriptional regulator	D2XQ27	Bacillus_virus	2.3e-59	94.5
WP_072770131.1\|17811_18156_+	hypothetical protein	NA	NA	NA	NA
WP_072770132.1\|18257_18482_+	hypothetical protein	NA	NA	NA	NA
WP_072770133.1\|18563_18752_+	hypothetical protein	NA	NA	NA	NA
WP_072770134.1\|18735_18987_+	hypothetical protein	NA	NA	NA	NA
WP_072770135.1\|19389_20154_+	hypothetical protein	A0A1L2JY44	Aeribacillus_phage	7.2e-57	56.0
WP_077393206.1\|20150_21371_+\|terminase	PBSX family phage terminase large subunit	A0A059T7K2	Staphylococcus_phage	8.8e-150	64.9
WP_072770082.1\|21383_22865_+\|portal	phage portal protein	E5DV51	Deep-sea_thermophilic_phage	1.3e-46	35.3
WP_072770137.1\|22983_23802_+\|capsid	minor capsid protein	A0A1S5SBA9	Streptococcus_phage	9.4e-31	33.5
WP_072770083.1\|23805_24006_+	hypothetical protein	NA	NA	NA	NA
WP_072770084.1\|24046_24301_+	hypothetical protein	A0A1B1P7N4	Bacillus_phage	6.5e-39	87.8
WP_072770085.1\|24399_25044_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_072770086.1\|25058_25991_+	DUF5309 family protein	D6PFH7	uncultured_phage	1.5e-19	28.3
WP_072770087.1\|26011_26209_+	hypothetical protein	NA	NA	NA	NA
WP_072770088.1\|26211_26553_+\|head,tail	phage head-tail connector protein	A0A097PAS2	Streptococcus_pyogenes_phage	5.0e-10	37.6
WP_072770089.1\|26549_26867_+	hypothetical protein	NA	NA	NA	NA
WP_072770090.1\|26850_27279_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_072770091.1\|27271_27679_+	hypothetical protein	NA	NA	NA	NA
WP_072770092.1\|27680_28208_+\|tail	phage tail protein	A0A0C5AMZ4	Paenibacillus_phage	1.0e-09	36.6
WP_072770093.1\|28210_28621_+	hypothetical protein	NA	NA	NA	NA
WP_042597357.1\|28644_28920_+	hypothetical protein	NA	NA	NA	NA
WP_072770094.1\|28919_31643_+\|tail	phage tail tape measure protein	A0A1B1P7P9	Bacillus_phage	2.6e-93	59.2
WP_072770095.1\|31639_32467_+\|tail	phage tail family protein	A0A0U4JNQ7	Bacillus_phage	1.1e-39	34.0
WP_072770096.1\|32481_33330_+	hypothetical protein	A0A0S2SXG8	Bacillus_phage	3.6e-17	71.2
WP_072770097.1\|33354_34101_+	SGNH/GDSL hydrolase family protein	A0A2H4J709	uncultured_Caudovirales_phage	1.4e-09	26.8
WP_072770098.1\|34217_36311_+\|tail	phage tail protein	A0A2H4JG80	uncultured_Caudovirales_phage	6.3e-172	60.7
WP_072770099.1\|36310_36493_+	hypothetical protein	A0A2H4JAY5	uncultured_Caudovirales_phage	1.5e-21	85.0
WP_072770100.1\|36479_36941_+	hypothetical protein	A0A2H4J980	uncultured_Caudovirales_phage	8.7e-50	81.1
WP_072770101.1\|36970_37459_+\|holin	phage holin family protein	A0A0M4R5G6	Bacillus_phage	2.9e-27	46.7
WP_072770102.1\|37461_37674_+	hypothetical protein	NA	NA	NA	NA
WP_072770103.1\|37673_38492_+	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	8.9e-138	84.6
WP_072770104.1\|38528_38762_-	helix-turn-helix transcriptional regulator	A0A0S2MVM0	Bacillus_phage	4.7e-36	97.4
WP_072770105.1\|38847_39378_-	hypothetical protein	A0A1B1P8A3	Bacillus_phage	1.7e-94	97.7
WP_072770106.1\|39389_39770_-	hypothetical protein	A0A1B1P8B2	Bacillus_phage	7.4e-55	88.9
WP_072770107.1\|39902_40166_-	hypothetical protein	NA	NA	NA	NA
WP_072770108.1\|40155_41166_-	plasmid segregation protein ParM	A0A2H4IZP5	uncultured_Caudovirales_phage	6.8e-31	31.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP014486

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014486_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014486_1

1086289-1086417

Orphan

Consensus_repeat	Method
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014486_1

>merge|NZ_CP014486|1|1086289-1086417|CRISPRCasFinder
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGGTTCAAGCCAAGTAACAGATGGTTTAGGAACATTATCTGTAGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG

>NZ_CP014486|1|1|1086289-1086417|CRISPRCasFinder
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG	TTCAAGCCAAGTAACAGATGGTTTAGGAACATTATCTGT
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014486.1\|WP_001068218.1\|1087992_1088346_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|379617
NZ_CP014486.1\|WP_000963381.1\|1083474_1084047_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP014486.1\|WP_000453703.1\|1075421_1076774_-\|DUF4026-domain-containing-protein	unknown	unknown	gnl\|CDD\|338635
NZ_CP014486.1\|WP_000140291.1\|1087660_1087966_+\|DUF2087-domain-containing-protein	unknown	unknown	gnl\|CDD\|226378
NZ_CP014486.1\|WP_000726775.1\|1072988_1073924_+\|ferrochelatase	unknown	unknown	gnl\|CDD\|183526
NZ_CP014486.1\|WP_000567010.1\|1090236_1090365_-\|YhfH-family-protein	unknown	unknown	gnl\|CDD\|379490
NZ_CP014486.1\|WP_065382105.1\|1091312_1092302_+\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
NZ_CP014486.1\|WP_065382104.1\|1081347_1083261_+\|M56-family-metallopeptidase	unknown	unknown	gnl\|CDD\|310280
NZ_CP014486.1\|WP_006916060.1\|1093031_1094564_+\|fatty-acid--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|236072
NZ_CP014486.1\|WP_063220298.1\|1092441_1092870_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000103715.1\|1089183_1090197_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP014486.1\|WP_001228071.1\|1073943_1075365_+\|protoporphyrinogen-oxidase	unknown	unknown	gnl\|CDD\|237009
NZ_CP014486.1\|WP_033684308.1\|1071927_1072974_+\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NZ_CP014486.1\|WP_065381842.1\|1077015_1079382_+\|chitobiase/beta-hexosaminidase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|225249
NZ_CP014486.1\|WP_001986098.1\|1087443_1087656_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000620467.1\|1088479_1088989_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP014486.1\|WP_000984145.1\|1079868_1080714_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000784668.1\|1090568_1091303_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293802
NZ_CP014486.1\|WP_001176848.1\|1079514_1079814_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000184504.1\|1080943_1081345_+\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747

Protein	Function_ID	Function_description	E-value
NZ_CP014486.1\|WP_001068218.1\|1087992_1088346_-\|PH-domain-containing-protein	gnl\|CDD\|379617	pfam14470, bPH_3, Bacterial PH domain. Proteins in this family are distantly related to PH domains.	9.48462e-20
NZ_CP014486.1\|WP_000963381.1\|1083474_1084047_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.571e-14
NZ_CP014486.1\|WP_000453703.1\|1075421_1076774_-\|DUF4026-domain-containing-protein	gnl\|CDD\|338635	pfam13218, DUF4026, Protein of unknown function (DUF4026). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 450 amino acids in length. The family is found in association with pfam10077.	6.14556e-177
NZ_CP014486.1\|WP_065382104.1\|1081347_1083261_+\|M56-family-metallopeptidase	gnl\|CDD\|310280	pfam05569, Peptidase_M56, BlaR1 peptidase M56. Production of beta-Lactamase and penicillin-binding protein 2a (which mediate staphylococcal resistance to beta-lactam antibiotics) is regulated by a signal-transducing integral membrane protein and a transcriptional repressor. The signal transducer is a fusion protein with penicillin-binding and zinc metalloprotease domains. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. homologs to this peptidase domain, which corresponds to Merops family M56, are also found in a number of other bacterial genome sequences.	8.25855e-47
NZ_CP014486.1\|WP_000620467.1\|1088479_1088989_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.55712e-15
NZ_CP014486.1\|WP_000567010.1\|1090236_1090365_-\|YhfH-family-protein	gnl\|CDD\|379490	pfam14149, YhfH, YhfH-like protein. The YhfH-like protein family includes the B. subtilis YhfH protein, which is functionally uncharacterized. Its expression is repressed by the Spx paralogue MgsR, which regulates genes involved in stress response. This family of proteins is found in bacteria. Proteins in this family are typically between 42 and 53 amino acids in length.	3.52581e-13
NZ_CP014486.1\|WP_065382105.1\|1091312_1092302_+\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	2.24017e-139
NZ_CP014486.1\|WP_000140291.1\|1087660_1087966_+\|DUF2087-domain-containing-protein	gnl\|CDD\|226378	COG3860, COG3860, Uncharacterized protein conserved in bacteria [Function unknown].	4.70267e-24
NZ_CP014486.1\|WP_006916060.1\|1093031_1094564_+\|fatty-acid--CoA-ligase-family-protein	gnl\|CDD\|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP014486.1\|WP_000103715.1\|1089183_1090197_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.56346e-114
NZ_CP014486.1\|WP_001228071.1\|1073943_1075365_+\|protoporphyrinogen-oxidase	gnl\|CDD\|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	0
NZ_CP014486.1\|WP_033684308.1\|1071927_1072974_+\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_CP014486.1\|WP_065381842.1\|1077015_1079382_+\|chitobiase/beta-hexosaminidase-C-terminal-domain-containing-protein	gnl\|CDD\|225249	COG2374, COG2374, Predicted extracellular nuclease [General function prediction only].	7.46719e-71
NZ_CP014486.1\|WP_000184504.1\|1080943_1081345_+\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	6.62394e-45
NZ_CP014486.1\|WP_000784668.1\|1090568_1091303_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.50066e-87
NZ_CP014486.1\|WP_000726775.1\|1072988_1073924_+\|ferrochelatase	gnl\|CDD\|183526	PRK12435, PRK12435, ferrochelatase; Provisional.	0

>NZ_CP014486.1|WP_000963381.1|1083474_1084047_+|TetR/AcrR-family-transcriptional-regulator
MAIDRKRSIIEAATKSFSAFGYKATTMDQVAKLANVGKGTIYTFFKNKEELFGEIISNLITEMKQVAESAIRSDVSFFENVHRALYSILEFRKEHQLMIKLIQEERDMGTKEVQEVMQQVDVEIVSVIQSYLKIAIEKGEISKCDPEITAFIMLRLYVSLIFDWEKNHEPLEKEKIAELFELYLLKGLSN
>NZ_CP014486.1|WP_065382104.1|1081347_1083261_+|M56-family-metallopeptidase
MINTLINVYLPHFFDWLIETSLMASILVGFILCIKVLFRNKLTPRWQYMLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPATENIVNIESDRKVELESNSKMVTKTSEPEVKVSSEKQTTFSLYKLALYVWLAGLIILAVITFLTNRRLYSYIKKQPDITDEQAITVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNEQQLQYVFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEEQIAYGHTIITLLQHYSYQVPSLANLSRNKRTLKRRIVMIKKFQKKSYRLSLLGVIAIVAIASLSLFNARATEGKEKQEDKVEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFLYHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQGDIKEVKEERLSTENREKLKEIRNKTTPYEDKVGKYLTYTVEEVQQHVDFKIKRPTYTIKGYTQKDERVNYYLKIKPEFTIELEYANGKGNYTISQSQVFGESKDPFSHQFIVTENIEKYELEGNQIFYATHHSDSNLQGMKMIVPAKGKDSAYQIVIINHSLEKQGEAVFDKNVNKEELEKVMLSMVK
>NZ_CP014486.1|WP_000184504.1|1080943_1081345_+|BlaI/MecI/CopY-family-transcriptional-regulator
MTNQLPKISEAELEIMKVLWSNSPQTANEIIEELEDAMDWKPKTIRTLINRLVQKEAVSYHQDKGRMYAYYPLVSQHNYLQVETKSLLKRFCGAAFKPLLVNFLKEEKLSSEDINELKRILDEKTEENKRKDR
>NZ_CP014486.1|WP_000984145.1|1079868_1080714_-|hypothetical-protein
MMRALRLNIKQAFCNRVSLIIMFSGFVLICIYHYYYVIRYLGDAANGPISTDIKWIGFRGNEMDVYLLLMPVIASLPFSTSYNSDKSDGFKPFVSKEISLFSYSVTKYIVTFFCGGLLYTFPFILSLLFCKLTIPDGVPTAGSGIINDNGMFANLYETSPITYIAVYIGINFLFAGLMALLGLAASAWSQKDYMALLFPFATTSIPYVLLNTVLPTIGGAPIHLYDPRQPLHGMSPYILTIQCAFFLFVSLIMYIQGVKRDRKKYRRRLQKRERCRKAFQV
>NZ_CP014486.1|WP_001176848.1|1079514_1079814_+|hypothetical-protein
MQLQINGKVMNQFAIFFSTIVMLQFVADITGLTSNLDITYNLIHTAASYITFSLAVIFTLIGARRELSKYAIVSLCLVIAIKAIYFVAVVILWGLAGTP
>NZ_CP014486.1|WP_065381842.1|1077015_1079382_+|chitobiase/beta-hexosaminidase-C-terminal-domain-containing-protein
MAVKKLLSVFLSFLLLLSFTGTLAQAEETASMSVEKAIQVFKQQGKTKGIVEGYIVGYTQSSSKYTKDPAKFDDTNVAIADSPNETNPDKIMPVQLPKGDVRTAVNVKDHPENIGKKVSLTGTLELYFSNPGLKSVTAYKFQGEGQNRVSDVVASPNGGEVAKGTAVTLTTNTEGATIYYTLDGSNPTNKSVLYNGQIIVNENSVVKAIAEKEGLTSSAISTFSFIIVNNEQVRIHDIQGKSHMSPYNGKKVNNVEGVVTALDKNGFYIEDNQPDNDPATSEGMYVYKKDANVAVGDLIQVDGVVEEYVGPGYAERFETDLTTTEIKASRVAVIAKDQSLPAPIVLGENGVKIPDQIIDNDAFSLFDPNEDAIDFYESIEGMRVTMPTPKIITPQKNGNLYVTVKNGGDKVVTQYGTPLLDENQLNPERLSVKVPRDYVAKVGDTFTGDITGVVGYDYGSFRISPITELPAVVDGGFKQVGANIQPRLDKLTVATYNIENFSANKKETTDEKVKALAYSIKYNLKMPDIIGVEEMQDNNGSINDGTTDASLSAKRIIDAVLEIRGPKYEYVEIAPNNNQDGGAPGANIRVGFFYNPSRVKLATVPKLLDKNVVRIGDENPLFESTRKPLAAEFTFQGQNIVVVANHLNSKLGDATPFGKVQPLVLKSEDKRIQLAQEVNHFVQGIQKKNTNAPVVVLGDMNDFEFSKPLKTLEGTILKDMLNTVPKENRYTYIHEGNAQVLDHILVTNNIAPHTIVDPVHLNSNIMKEHGRVSDHDPVLAQIDLKKAS
>NZ_CP014486.1|WP_000453703.1|1075421_1076774_-|DUF4026-domain-containing-protein
MEVQTETYRAAMNGTLERHFSDMIAVIPTRITIEQLKQRLENIATKVDELKIVYSDETSLIVELHMDETIIPYELHIDEANDPEEYKMYNRQDSTIVDRNFEDAAFGTEIFTRTLFVGDVLDCFFQQIQFLWNLAPDLLFVIDSSAAMKVISRNYIEYHVENELLPDIPDLYVIHSVYEDDKEGEPTQYWFHTHGLLRAGVTEIELIIPNRISSYYGIGDLFQTFANNAVENGQVPMNEPIVIAHSQQGSIHTVAVPWEKGLSYIGHKTSMDQLSSIEDEEVKLQPIDAQNTFLGGMDARDEYHQSPSVLLFKFNTSEEYIESFFKEHEEATGLMFYKTNSETDRMAYNAKNTFGYFSNIFQIEKSNEEFRFLAKFGVSYEEGKSEHMWFEMQHITEDLIQGILINEPYFIEDMSEGNSYHLDFDNLTDWVIYAGDAVIKPNNLYMFIGE
>NZ_CP014486.1|WP_001228071.1|1073943_1075365_+|protoporphyrinogen-oxidase
MRKKVVIIGGGITGLTAMYNLQKNIHEKNLPIDTLLIEASGKLGGKIQTVRKDGFTIERGPDSFLARKESAARLVKELGLGDELVNNQAGQSFILVNNRLHKMPNGSMMGIPTQITPFLFSGLFSPIGKLRAGFDLLMPRSKPVSDQSLGQFFRHRLGNEVVENLIEPLLSGIYAGDIDEMSLMSTFPQMYQIEQKHRSISLGMRTLAPKEEKAEPKKGMFQTVKTGLESIVKSLEAKMHEGTIIKGTRIEKVAKQGDGYTITLSNGKEIEADAIVVATSHKVLPSMFAQYKQFRFFRNIPSTSVANVALAFQKSAIQRDINGTGFVVSRNSDYTITACTWTHKKWPHTTPEGKTLLRCYVGRAGDEAVVEQTEEELVQLVLEDLRKTMDITEDPEFTIVSRWKEAMPQYTVGHNERMKKLTTFMEKELPGIYLAGSSYAGAGLPDCMNQGEEAAKRVLSHLEKVIDAELIAQ
>NZ_CP014486.1|WP_000726775.1|1072988_1073924_+|ferrochelatase
MKKKIGLLVMAYGTPYKEEDIERYYTHIRRGRKPSPEMLEDLTERYRAIGGISPLATITLEQAKKLEKRLNEVQDEVEYHMYLGLKHIEPFIEDAVKDMHNDGIQDAIALVLAPHYSTFSVKSYVGRAQEEAEKLGNLTIHGIDSWYKEPKFIQYWVDAVKGIYNGMSDAEREKAVLIVSAHSLPEKIIAMGDPYPDQLNETADYIARGAEVANYAVGWQSAGNTPDPWIGPDVQDLTRELNEKHGYTSFVYAPVGFVAEHLEVLYDNDFECKVVTDEIGAKYYRPEMPNASDAFIDCLTDVVLKKKESVL
>NZ_CP014486.1|WP_033684308.1|1071927_1072974_+|uroporphyrinogen-decarboxylase
MVRTINETFLKACRGERTDYVPAWYMRQAGRSQPEYRKIKEKYSLFEITHNPELCAYVTKLPVDQYNVDAAILYKDIMSPLPAIGVDVEIKSGIGPVIDNPIRSLQDVEKLGEINPEDDVPYILDTIRLLTTEMLDVPLIGFSGAPFTLASYMIEGGPSRNYHNTKAFMYAEPKAWFALMDKLADMVITYLKAQINAGAKAVQIFDSWVGTVNVADYRVFIKPAMERIFAEVRKMDVPMIMHGVGAAHLVNEWHDLPLDVVGLDWRLPIEEARARGVHKAVQGNMDPSFLLAPWSVIEEHVKSILDQGMKQPGYIFNLGHGVFPEVNPDTLKRLTTFIHEYSKGQLAK
>NZ_CP014486.1|WP_001986098.1|1087443_1087656_+|hypothetical-protein
MMKGNLTYYFIVNPLIIFLVYALSPILFDKEVYTSMKDAFGILTFYYVLMGGYYFIDILSEKIKKKSDGG
>NZ_CP014486.1|WP_000140291.1|1087660_1087966_+|DUF2087-domain-containing-protein
MTESEMKFRDTTIRNFFDKEDRLKSIPGQKKKKLVLLEHLISKLNAENQYTEKEINTFIKQYHDDFCTIRREFIVQGFMNREDNMYCINGREVWTKWEELK
>NZ_CP014486.1|WP_001068218.1|1087992_1088346_-|PH-domain-containing-protein
MNPILTAAKQLLHKEEKILSTLKCSLTGYMITHKVPYPGMLLATNQRLLFFSQYKNTFIAEFDYEKILSIETKRRIFDKKIIFYYEDEHITLGYITSSNVEAFIDLLQRNSKTSTGL
>NZ_CP014486.1|WP_000620467.1|1088479_1088989_+|GNAT-family-N-acetyltransferase
MIRLVKETDAEAIMNIRKEIILSETTTKFFIVSPKKLPNDMNAEREKIRKSNEKGNLYIVYEVDGKVVGFLIFNRYELERLQHAGTMGMGIKEAYCNQGIGTKLIEFLISWAKGQKGLEKICLGVVSVNDRAIKVYKRMGFVEEGRQRKQIKYEDGSYGDDVLMGFYIE
>NZ_CP014486.1|WP_000103715.1|1089183_1090197_+|LacI-family-DNA-binding-transcriptional-regulator
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLDQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAILAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFELELLVKGSTMKDKMLLA
>NZ_CP014486.1|WP_000567010.1|1090236_1090365_-|YhfH-family-protein
MIDQPMEFFRNLPTKTCAHCGKEIDEQHEAYHNKCDDCVHEE
>NZ_CP014486.1|WP_000784668.1|1090568_1091303_+|MBL-fold-metallo-hydrolase
MKMTVVGFWGGFPEAGEATSGYLFEHDGFRLLVDCGSGVLAQLQKYITPSDIDAVVLSHYHHDHVADIGVLQYARLITSATTRQLPELPIYGHTFDENGFHSLTHEPHTKGIAYNPEETLQIGPFSISFLKTVHPVTCFAMRITAGSDIVVYSADSSYIPEFIPFTKDADLFICECNMYAHQEAAKAGHMNSTEVASIAKDANVKELLLTHLPHTGNPSDLVTEAKQIFSGHITLAHSGYVWNS
>NZ_CP014486.1|WP_065382105.1|1091312_1092302_+|lipoate--protein-ligase
MLFIDNKGITDPRINLAIEEYCLKNLDINETYLLFYINEPSIIIGKNQNTVEEINADYVKEKGIHVVRRLSGGGAVYHDLGNLNFSFITKDDGDSFSNFKKFTEPVTKALSKLGVNAELSGRNDILAEGRKISGNAQFATKGRMFSHGTLLFDSEIDHVVSALKVKMDKIQSKGIKSIRSRVANITEFLNEEMTTEEFRQLLLETIFEGETEIPTYELTENDWKEIHKLSEERYQNWDWNYGKSPKFNLQHSHRFPVGQVDVRLEVKKGTVTECKIYGDFFGSLDVHDIEERLTGVQFDKDAFTAALEGVDIARYFGNITTEDFLHLFF
>NZ_CP014486.1|WP_063220298.1|1092441_1092870_+|hypothetical-protein
MKRVMYVILLLSFVIGMTACNSGLPSSRTILSIGKPAEDNVIYFTHTDNRRKIQEIQDMFQNKKWKRNETFSTVNKTPDVVFSIDEDNTGLPTLYVTVYFHEDGADALNLHGEHTTLNKEELNKLREKMNAYYPKMISGLVS
>NZ_CP014486.1|WP_006916060.1|1093031_1094564_+|fatty-acid--CoA-ligase-family-protein
MNLVQSLAETAKKKGDKPAYIFMDQSVSYDQLNKMVTRFSGNLAEMGIGKGDNVALVVGNSPHFLVGLYGTMKAGATVIPVNPIYTADEMHYILQNGDVKTIIVLDVLLPVIQSLTTRLPSLENIIICETSSDFNHTETEKMKTFTSFVGTGDTTYEGPELDEEDVAVILYTSGTTGKPKGAMLTHKNLYSNASDVASYLQYTADDRVVAALPMFHVFCLTVAVNAPIVNGATILMLPKFSPKEVFRICRTYEPTIFAGVPTMYNYLYLFEEASAEDVKTLRLCISGGASMPVALLQNFEKRFNVIVSEGYGLSEASPVTCFNPLDRPRKPGSIGTNIWHVENKIVNELGEEVPVGAVGELIVRGPNVMKGYYNAPEDTAATLKDGWLYTGDLAKMDEEGYFYIVDRKKDIVLVGGYNVYPREVEEVLYTHESVAEVVVIGVPDENLGEAVRAYVVLKQTNVTEEELMHYCTLHLAKYKVPKSIEFLIELPKNTTGKLLRRALREKAMQV

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Crispr_ID: NZ_CP014486_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014486_2

2774402-2774558

Orphan

Consensus_repeat	Method
TTAAGGAATGAATATTCATTCCTAT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP014486_2

>merge|NZ_CP014486|2|2774402-2774558|PILER-CR
TTAAGGAATGAATATTCATTCCTATTATTCTATTACATTATTTGTAAACTCTATTAAACTAGTCTTTCCGGAATGAATATTCATTCCTTTAGTTGCACAAATACCCTCTCCTACTCTCATTTTTTAATTCTATTTAGGAATGAATATTCATTCCTGT

>NZ_CP014486|2|1|2774402-2774558|PILER-CR
TTAAGGAATGAATATTCATTCCTAT	TATTCTATTACATTATTTGTAAACTCTATTAAACTAGTCTTTCC
GGAATGAATATTCATTCCTTTAGTT	GCACAAATACCCTCTCCTACTCTCATTTTTTAATTCTATTTA
GGAATGAATATTCATTCCTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014486.1\|WP_000923471.1\|2761503_2762187_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|132880
NZ_CP014486.1\|WP_065382635.1\|2775372_2776530_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226925
NZ_CP014486.1\|WP_001273575.1\|2781628_2782705_-\|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase	unknown	unknown	gnl\|CDD\|183614
NZ_CP014486.1\|WP_000371021.1\|2763215_2764037_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293813
NZ_CP014486.1\|WP_000633864.1\|2769319_2770945_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
NZ_CP014486.1\|WP_065382606.1\|2777961_2779062_-\|prephenate-dehydrogenase	unknown	unknown	gnl\|CDD\|235824
NZ_CP014486.1\|WP_000802424.1\|2760785_2761487_-\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143393
NZ_CP014486.1\|WP_000346930.1\|2766087_2766762_+\|TerC-family-protein	unknown	unknown	gnl\|CDD\|163429
NZ_CP014486.1\|WP_072769980.1\|2780173_2781346_-\|chorismate-synthase	unknown	unknown	gnl\|CDD\|171518
NZ_CP014486.1\|WP_000551452.1\|2764329_2765157_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200569
NZ_CP014486.1\|WP_000808770.1\|2766818_2768792_-\|LTA-synthase-family-protein	unknown	unknown	gnl\|CDD\|224287
NZ_CP014486.1\|WP_000997702.1\|2787196_2787634_+\|YndM-family-protein	unknown	unknown	gnl\|CDD\|371204
NZ_CP014486.1\|WP_000800667.1\|2762637_2763027_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|366361
NZ_CP014486.1\|WP_001197280.1\|2779054_2780155_-\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|134568
NZ_CP014486.1\|WP_001107309.1\|2774576_2775143_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|292911
NZ_CP014486.1\|WP_100650505.1\|2783532_2787015_-\|DUF4020-domain-containing-protein	unknown	unknown	gnl\|CDD\|372518
NZ_CP014486.1\|WP_000637704.1\|2765314_2765977_+\|DUF3841-domain-containing-protein	unknown	unknown	gnl\|CDD\|378997
NZ_CP014486.1\|WP_000664630.1\|2776654_2777944_-\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_CP014486.1\|WP_000709538.1\|2787784_2788315_-\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496
NZ_CP014486.1\|WP_139256942.1\|2771244_2774367_-\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|225272

Protein	Function_ID	Function_description	E-value
NZ_CP014486.1\|WP_000923471.1\|2761503_2762187_-\|DNA-alkylation-repair-protein	gnl\|CDD\|132880	cd06561, AlkD_like, A new structural DNA glycosylase. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity.	1.59053e-27
NZ_CP014486.1\|WP_065382635.1\|2775372_2776530_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226925	COG4552, Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only].	3.85905e-70
NZ_CP014486.1\|WP_001273575.1\|2781628_2782705_-\|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase	gnl\|CDD\|183614	PRK12595, PRK12595, bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed.	0
NZ_CP014486.1\|WP_000371021.1\|2763215_2764037_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293813	cd07727, YmaE-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YmaE and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YmaE and Nostoc all1228 proteins.Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry. .	6.5129e-65
NZ_CP014486.1\|WP_000633864.1\|2769319_2770945_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP014486.1\|WP_065382606.1\|2777961_2779062_-\|prephenate-dehydrogenase	gnl\|CDD\|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	1.4308e-158
NZ_CP014486.1\|WP_000802424.1\|2760785_2761487_-\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	5.83137e-09
NZ_CP014486.1\|WP_000346930.1\|2766087_2766762_+\|TerC-family-protein	gnl\|CDD\|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	6.12596e-74
NZ_CP014486.1\|WP_072769980.1\|2780173_2781346_-\|chorismate-synthase	gnl\|CDD\|171518	PRK12463, PRK12463, chorismate synthase; Reviewed.	0
NZ_CP014486.1\|WP_000551452.1\|2764329_2765157_+\|polysaccharide-deacetylase	gnl\|CDD\|200569	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins. This family is represented by a putative polysaccharide deacetylase PgdA from the oral pathogen Streptococcus mutans (SmPgdA) and Bacillus subtilis YheN (BsYheN), which are members of the carbohydrate esterase 4 (CE4) superfamily. SmPgdA is an extracellular metal-dependent polysaccharide deacetylase with a typical CE4 fold, with metal bound to a His-His-Asp triad. It possesses de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. SmPgdA plays a role in tuning cell surface properties and in interactions with (salivary) agglutinin, an essential component of the innate immune system, most likely through deacetylation of an as-yet-unidentified polysaccharide. SmPgdA shows significant homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae (SpPgdA) and Listeria monocytogenes (LmPgdA), both of which are involved in the bacterial defense mechanism against human mucosal lysozyme. The Bacillus subtilis genome contains six polysaccharide deacetylase gene homologs: pdaA, pdaB (previously known as ybaN), yheN, yjeA, yxkH and ylxY. The biological function of BsYheN is still unknown. This family also includes many uncharacterized polysaccharide deacetylases mainly found in bacteria.	2.17052e-82
NZ_CP014486.1\|WP_000808770.1\|2766818_2768792_-\|LTA-synthase-family-protein	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_CP014486.1\|WP_000997702.1\|2787196_2787634_+\|YndM-family-protein	gnl\|CDD\|371204	pfam10710, DUF2512, Protein of unknown function (DUF2512). Proteins in this family are predicted to be integral membrane proteins, and many of them are annotated as being YndM protein. They are all found in Firmicutes. The true function is not known.	8.18943e-46
NZ_CP014486.1\|WP_000800667.1\|2762637_2763027_-\|VOC-family-protein	gnl\|CDD\|366361	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	9.83918e-12
NZ_CP014486.1\|WP_001197280.1\|2779054_2780155_-\|histidinol-phosphate-transaminase	gnl\|CDD\|134568	PRK01533, PRK01533, histidinol-phosphate aminotransferase; Validated.	0
NZ_CP014486.1\|WP_001107309.1\|2774576_2775143_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|292911	pfam16295, TetR_C_10, Tetracycline repressor, C-terminal all-alpha domain.	8.56994e-64
NZ_CP014486.1\|WP_100650505.1\|2783532_2787015_-\|DUF4020-domain-containing-protein	gnl\|CDD\|372518	pfam13212, DUF4020, Domain of unknown function (DUF4020). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is typically between 176 and 195 amino acids in length.	1.75803e-74
NZ_CP014486.1\|WP_000637704.1\|2765314_2765977_+\|DUF3841-domain-containing-protein	gnl\|CDD\|378997	pfam12952, DUF3841, Domain of unknown function (DUF3841). This presumed domain is around 190 amino acids in length. As yet no function has been given to any member of the family.	7.34499e-34
NZ_CP014486.1\|WP_000664630.1\|2776654_2777944_-\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_CP014486.1\|WP_000709538.1\|2787784_2788315_-\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	2.51794e-62
NZ_CP014486.1\|WP_139256942.1\|2771244_2774367_-\|MMPL-family-transporter	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	5.39808e-78

>NZ_CP014486.1|WP_139256942.1|2771244_2774367_-|MMPL-family-transporter
MSKLKNWRSLSFLLWIVITITMIVTMPNMDKLVKEKGHITIPNTEQSSIADKMIKEMDKDGTEKYDIIVVFNSDSKTALTTEQKEEIIKTINALQNEKEQLGIKEVVSHLDNKELEKQLVSKDNTTILTQISIDKKHGEISKVTNNLHNKVKMKGVTTYLTGSDLIAGDFLTSSQEGVKKTEVISIIFILVILIIVFRSPIVPIVSLLTVGVSYLVSMGIIAHLVDQFNFPFSNFTQVFVVVVLFGVGTDYNILLFTRFKEELSKRENAFLATKETFKSAGKTVLYSGIAVLIGFASLALASFKLYQSTSAVAIGVAVLLLVLTTLNPFFMVLLGKGMFYPVKTFKGHEDSRLWGFFAKNSVVRPFVALIIVFVISIPFILKYSNTLNYNDLFEVDNKYESKMGINVIEEHFPPGFSSPSTLVIQSNNKLDEASSLQALDELTDKILKVKGVSEVYSPTRPTGDRIKELYINKQAGELNTGLGDANGGIKEINDGLTTAKDKMGNKDSNSLANVQKLIDGTNEAKSGVSALGTALNQLSNGINDGAQGARQIESGLTSVNENISVLSQATSQLHAGYTQLEKGLSSYDQYFGSISQAIDGAKKGYEQIEMLMTNFIQTKPELANDPNILQTIGIAKEAQKQLGGLSNELNKLKAQHNAAMGSFKEANQSLLKVDNGLKEMNNGVTKLQKGAADLKNGLNEGASGSKQIANKSSELQTGLTKINDGQGQLLTGLKDLQEQMGQLQSGLTKSTEGLEKVSNGLGDAQKYLGELNESKSSEKFYIPKEVLEGEDFQKALNTYMSHDRKTAKMTIILDVNPYSKEAMPIIQEINNTIDGTLKGSELNHAKTAIGGTTARNVDLKEVTGQDFLRTATIMLIGIAIVLIVITRSLLNTIFIIGSLLLAYFASLGISEQISTHILHVDSLSWNVPFFSFIMIVALGVDYSIFVMMRYNELEGDPATKIVTASRHIGGVVLSAALILGGTFAALIPSGVLTLIQVASVVGVALLLLALIVMPILLPALIGLTSKMKSYKEKIRNKKRL
>NZ_CP014486.1|WP_000633864.1|2769319_2770945_-|ATP-binding-cassette-domain-containing-protein
MITVSNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIEPSTGDIHITPGERLAVLKQNHFEYEEFPVLETVIMGHTQLYKVMQEKNAIYMKEDFSDEDGMRAAELEGEFAELNGWEAESEAAILLKGLGIGEDLHDKKLSELTGAEKVKVLLAQALFGQPDILLLDEPTNHLDLKAIQWLENFLMNFENTVIVVSHDRHFLNKVCTHMADLDFGKIQLYVGNYDFWYESSQLALKLTQDANKKKEEKVKELQNFIARFSSNASKAKQATSRKKLLDKITLDDIRPSSRRYPFVGFTPEREVGNDLLTVEGLSKTIDGEKVLDNVYFTLNKGDKVAFIGRNDIAMTTLFKILMGEMEPDSGSFKWGVTTSQSYFPRDNSKYFENSDYNLVEWLRQFSPQDESESFLRGFLGRMLFSGEEVKKNVSVLSGGEKVRCMLSKMMLSGANVITLDDPTNHLDLESITALNNGLIAFKGTILFTSHDHQFVQTIANRIIEVTPNGVIDKEATYDEFLENEELQKQVDAMYKGQ
>NZ_CP014486.1|WP_000808770.1|2766818_2768792_-|LTA-synthase-family-protein
MKQFLLKSKSVLSNHFGFFLFAVILLWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAVLFLGLALFAKGKRSYIWLIIINLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGSILALLHLYDPLYFLDTIILIVLVATKFANPKPIRVAKHKLSLVFVAGILLFSVNLGLAESDRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYASPNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQGSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNEKDVVNYGLKDKPFFNESIPLLQTLKQPFYTKFITLSNHFPYPIDKAEATIEPATTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHYGISDNHNAAMSKVMGKEMNSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLLGTDTKNYVQFGSDLLSPDHKQVVAFRNGNYVSPTVTALNGKYYDTTTGKPVEFTDEIKKNEQMVQNSLKYSDQVVNGDLLRFYTPEGFTPVDRSKYNYNNRDKNKTKVKTTPEGEAK
>NZ_CP014486.1|WP_000346930.1|2766087_2766762_+|TerC-family-protein
MDFLSAEYLSALLAIIVIDLVLAGDNAIVIGLAARRLPKDQQKKVIIWGTIGAIAIRALATLVVVWLLKIPGLLLIGGVLLIWIAYKLIAEGKDHDIKAEEGFWSAIKTIIIADALMGIDNVLAVAGAAHGNFSLVIIGLLVSIPVVVWGSTLILKWVDRFPVIITIGAAVLAYTAAKMIVDEKWFAGFFESNPFVKWAFIIIIIIGVVFFGKAKQKATAGSVS
>NZ_CP014486.1|WP_000637704.1|2765314_2765977_+|DUF3841-domain-containing-protein
MIVYTVQTEEAWKQFKKLGYLEGNKEFIDPDDVYSYDWMVRVAKTRLPHYEGNYPIWVWEANNYPNRNHKAWGRTNSKMVILTLDVPKEWVLWSYFDYWCCAMTDGSTYLHTKNKCTLDEWYTYMDKEYGIIFDFDYLLSHPDWCLGKEDSLEKQGVIGKIPLSFVKKVRRFRAKTDKSISKIRSDNWDNRKENRIKKMNRKLRKRNDKQKRIQKRLIRN
>NZ_CP014486.1|WP_000551452.1|2764329_2765157_+|polysaccharide-deacetylase
MHNGIRMTTLVKRAMLVCAGVLFTYEVAFGSVHTALASTEDEAKSVQLVSEIQTSLAPKEAPKHYNGQVRKVAYLTFDDGPGKYTAELLDMLKKENAKATFFLIGSNVKAFPDLVKREDAEGHYVGMHSMTHNYKKLYTEGHYVDEMKEDQGLIAGVLGKSPVLTRPSYGSMPGLNEALRNKVVENGLKVWDWTIDSLDWKYNKMQVDAASAKIVENVLHGATNPTEVILMHDIHPQSVKAVPGIIKGLKEKGYELEAYNENEHFPLNFWHDNRM
>NZ_CP014486.1|WP_000371021.1|2763215_2764037_-|MBL-fold-metallo-hydrolase
MDNYICTTCGVQYPENEEAPSRCKICNEERQYVNPIGQSWTTLETMQNSNLYKNEIIKEESGLYSITTKPKFAIGQTAFLIQSKTLNVMWDCISYLDDKTIQRIYDLGGIQAIALSHPHYYSTQVKWAETFNVPIYIHEDDKEWVVRPSKQIKFWSGEHLILSEELTLHRLGGHFKGGTVIHWKDGNEGKGILLSGDIIQVVSDRKWVSFMYSYPNLIPLPANKVRDMAEKVKDIQFSRLYNAFHGVVEDANKAVQRSADRYIKALQGELFHT
>NZ_CP014486.1|WP_000800667.1|2762637_2763027_-|VOC-family-protein
MKNWVQFRIARPTDKFEEVISFYETGLGLKRIGEFHNHEGYDGVMFGLPDEEYHLEFTTHVNGSPCPAPTKDNLLVFYMPIKDEIEKIVNRLSNMGYHEVEPENPYWIEKGTTIEDPDGWRIVLMNASE
>NZ_CP014486.1|WP_000923471.1|2761503_2762187_-|DNA-alkylation-repair-protein
MLLEEVMRQLEEYGTEQNRKTYKNHGAKEPLFGVSFANLKLLKKKIKKDHDLAVELWETKNMDAMTLATYILDPKKITTEQLNSWIQDVDYYCLMDVLMTSICTSPIAIERMEEWTKSNDEWIGRAGWSLLANIAIKNKTLHDDFFSPYLEEIKENIHNEKNRKKEAMNSALIAIGIRNEDLERQAIEIASEIGKIEVDHGATSCKTPDAESYIKKARERAEKKKVK
>NZ_CP014486.1|WP_000802424.1|2760785_2761487_-|nucleotidyltransferase-domain-containing-protein
MKPIEAAQNIITLQFPNCDVALLGGSVARGEATKTSDLDIVIVDQSLTSCYRESFYSNGWPVEVFVHNFETYKTFFKMDCDRGRPSLPQLVSEGIALKGEQEIVEKLKKEANDLLHKGPAKWTEETIKQKRYFITDTLDDFIGATKREEELFIANLLADLVHEYVLRVNGKWLGSSKWFIRVLKRYDEQYANKFVAAFDHFYKTGGKNELIHFIEKTLEQYGGRVFEGFSIGK
>NZ_CP014486.1|WP_001107309.1|2774576_2775143_-|TetR/AcrR-family-transcriptional-regulator
MAKNKQEDIFDAAMQLFAERGYDGTTIPMIAEKANVGAGTIYRYFENKEALVNSLFSKSMLQLSEMIKTDFPVEANIREQFSHTYNRLFEFARNNVDAFLFTNSHCDSYFLDEQSKKIFDDFIGFFMNIIEDGIAKGLLRPLPPVALIIIVYQPLEKLTKVIATGQLEYSKELVKELEESSWNAIRII
>NZ_CP014486.1|WP_065382635.1|2775372_2776530_-|GNAT-family-N-acetyltransferase
MNVIQLKEDKFREALRLSEYAFQYKVEEERMQQQLTKMKESHEVYGIMEGEDLAAKLHLIPFHIYIGKEKFKMGGVAGVATYPEYRRSGYVKELLQHSLQTMKKDGFTVSMLHPFAVTFYRKYGWELCANLLVCHLTKSDLVMKKQVNGTVKRFNKENHPEEVEKLYETFAERFSGMLVRNEKWWLQAVYEDLTLAIYYDENKTAAGYMLYKIENYKMTVDEFVPLHNEARNGLWNFICQHDSMIKELEMTVSENEQLLYTLQEPRVKTEIKPYFMGRIVDVEQFLKQYELNWNNVQQEVILHITDSFAPWNNVSVRLANYEIAIIEEPMDKGINLDINALSTILLGYKRPLELNELELISGSEEEIRAFENVVPVRKSFIYDFF
>NZ_CP014486.1|WP_000664630.1|2776654_2777944_-|3-phosphoshikimate-1-carboxyvinyltransferase
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGSIAEGKTTIKGFLPGADCLSTISCFKEMGVEITQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDESIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYISPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLSGGQKLTATDIQVPGDVSSAAFFLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVDLINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCLAEGKTIIEDAEAVGVSYPTFFDELQKLAK
>NZ_CP014486.1|WP_065382606.1|2777961_2779062_-|prephenate-dehydrogenase
MRKKVVLIGTGLIGGSLALAIKKEHDVTITGYDIFQEQVERAKELHVVDEIAVDLQLACEKAHLIVFASPVEETKKLLHKLASFRLREDVIVTDVGSTKGTIMNEAETLFSKEVSFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMHHVPNEQVEELKDWLKGTGSHFLVLNTEEHDYVTGIVSHFPHLIAAGLVKQVEKHAGDNPLIHQLAAGGFKDITRIASSSPKMWSDIVKQNREHLMVLLKEWISEMEDLYKTVSTGDACEIQNYFADAKEYRDSLPVRKRGAIPAYHDLYVDVLDKVGALAHITSILAREEISITNLQILEAREGLLGVLRISFQREEDRMKAKLALGEEEYQTYETI
>NZ_CP014486.1|WP_001197280.1|2779054_2780155_-|histidinol-phosphate-transaminase
MQVKDQLSSLQPYKPGKSPEQMKEVYGDHSFVKLASNENPFGCSSRVLDELQKSWLEHALYPDGGATTLRQTIADKLHVKMEQVLCGSGLDEIIQIISRAVLRAGDNIVTAGATFPQYRHHAIIEGCEVKEIALNNGVYDLEEISSVVDNDTKIVWICNPNNPTGTYVNDRKLTQFIEGISENTLIVIDEAYYEYVTAKDFPETLPLLEKHKNILVLRTFSKAYGLASFRVGYAVGQEELIEKLNVVRLPFNVSSLAQKAATIAFGDDEFIEEIVRVNTEGLQQYESFCRENDIPFYPSQTNFIFLPVENAGEIYEACAHAGFIIRPFPNGIRITVGTREQNEGVISVLQQHFENKKRKSRDEENA
>NZ_CP014486.1|WP_072769980.1|2780173_2781346_-|chorismate-synthase
MRYITAGESHGPQLTVILEGVPAGLTLTAEHINKELLRRQKGHGRGRRMQIETDTVEIVSGVRHGMTLGSPITLIVKNDDFKHWTKVMGAEPISEKESKDMKRTITKPRPGHADLNGAIKYGHRDIRNVLERSSARETTVRVAAGAVAKQILSELGVEIAGHVLEIGGVKAKHISNLSIEEIQTITENSPVRCLDKEVEQEMMNAIDNAKSSGDSIGGIVEVIAEGMPIGVGSYVHYDRKLDAKLAGAIMSINAFKGAEIGVGFEAARQPGSKVHDEILWDGEKGYTRRTNNAGGLEGGMTTGMPIIVRGVMKPIPTLYKPLASVDIDTKEAFQASIERSDSCAVPAAGVVAESVVAWELADALVEQFGKDRMELLKQNIMQHNNYAKEF
>NZ_CP014486.1|WP_001273575.1|2781628_2782705_-|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase
MANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAEHNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGTQTFIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDEFINAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVIVDVTHSTGRRDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMDELKGFKNKLS
>NZ_CP014486.1|WP_100650505.1|2783532_2787015_-|DUF4020-domain-containing-protein
MWITSEVEIPDELIDHLEQGKLVLFVGAGVSMKGKSNLPNFDDLVDEIAKTLYVEKREITEPHDYYLGKIAKTKDVHQVARDLVHIEKSKPNPLHYAIPRLFPLDTDIRIVTTNFDQHFTTAIKEINRDINVYYAPALPTGRAFKGLAYIHGNVEQEKEALILTDGDFGRAYLTEGWARRFLVDLFSNYTVLFVGYSHNDPVMKYLATGLPPSTRRFAFVAQGENTYHWEHLGIRPIVYPNKVNNHQSLVKAVKRWAELMGDNYITKRMRIRDIVTVPPSVEQEQLSYIKQSIKKIETVRYFVEFAHDYEWVEWLEVEGKLQNLFMLTPNYNEVDELLAEWLVEQFLFSHQKELFQLIYKNYSKISPLLWRTICNYLTETKSKMDPLLFARWTLLLLETAEKDSSSIEKISKLLQKCSFPEHKEIALLLLTFILDGKLKLKRVRKWGNDTQESIELEESSRLPVSTFSHVEQIWNEKMRPYIAYYAVPIMMIGLEKLRMLSLRQTALKKRNKENVEKEFHQNDLAFLIRIVKECLTYLCENNEKKADYYITEMIEANSVLQKRIAIDAMNKNIFVRVDDKMKWLLHEGLLLDFTYKHEVFQLLKRHYAHCLEKTKEEVTRTVIKHLTEERVFDACLVLDLLFKCDSNSPSTANGYELMKQKHPHFHSERYSVQKKEDTEQSITCNVTADGLLQLKDVEIMKQVQQFSQDGVFEQRHFLEMLSKACKLNTEWSISFAYQLVGVQEISNEVWFVCIREWRNNRGLTNEQIQKIIPLLQKFIRNTAFHWLISSFLYEISNRLEELEENSIRVVKRFAFSVFPQVMKSDTDFKLGKQDFYNESIQHPVGKMTAVLLKLLSYDHLYDRNVYEYLFLFEEQVRVNSERTNFMFARLIADITFLYHIEKQWCRKYLLPYLDLKKQNEITEYAWAGLCYTQINLPLFTEMKRFIKYAIEHLEVLHPHTREAFLKWLSFVFIKCVLYWEQKTDWLYPLLILENEENKIKFMQFLCYYVKTLSVKEQQKFWTAWLSVFLRERPKMGEITAREYVMLLRIILYMDEILEKGLCIMSRAFSSVHGKCAGEEMKQLLIEMLHKKESMKAHKEIFANVFFILLQTCHEAVLFEKEIIKIKELLVQYEVEGYVLHLLENEIIRIGIVMGDLQKEL
>NZ_CP014486.1|WP_000997702.1|2787196_2787634_+|YndM-family-protein
MNDFTVVLIKFISCIIAFSIGLALFFPATFVQIISFSLFVTIVSYMFVDKIILNRIGNTGAIMSDFLLTYLSVWIFGNILLDNYMQIAWGSILSAIVFTLSEVIVHRFSNSHTRHNNDNIRINRRFAYGTEFAEEQNILDKDKKK
>NZ_CP014486.1|WP_000709538.1|2787784_2788315_-|cysteine-hydrolase
MKKALIVIDVQAGMYTAGMPVHNGGKFLQTLQELIRECRSNDIPVIYIQHNGPKDHPLEKGTDGWRIHAAIAPQEGDNIVEKTTPDSFHNTNLSEVLQEKEIEHVILSGMQTEYCVDTTTRRACSEGYKVTLVSDAHSTFNTEVLRAEDIVKHHNAVLGAFADVVAVKDLKVAASK

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Crispr_ID: NZ_CP014486_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014486_3

3223198-3223350

Orphan

Consensus_repeat	Method
ACCAGTTGGACCGGTTGGACCAGT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP014486_3

>merge|NZ_CP014486|3|3223198-3223350|PILER-CR
ACCAGTTGGGCCGGTTGGACCATTTTCTCCTTGCACCCCTTGCACTCCTTGTATTCCTTGTGGGCCGGTTGGACCGATTGGACCTTGTACGCCTTGTATTCCTTGCGGTCCAGTTGGTCCACCTAAAGCACCAGTTGGACCGGTTGGACCAGT

>NZ_CP014486|3|2|3223198-3223350|PILER-CR
ACCAGTTGGGCCGGTTGGACCATT	TTCTCCTTGCACCCCTTGCACTCCTTGTATTCCTTGTGG
GCCGGTTGGACCGATTGGACCTTG	TACGCCTTGTATTCCTTGCGGTCCAGTTGGTCCACCTAAAGCACC
AGTTGGACCGGTTGGACCAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014486.1\|WP_000350943.1\|3232735_3233272_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000938438.1\|3228303_3228852_-\|DUF2179-domain-containing-protein	unknown	unknown	gnl\|CDD\|235234
NZ_CP014486.1\|WP_050252092.1\|3223450_3225958_-\|collagen-like-protein	unknown	unknown	gnl\|CDD\|367362
NZ_CP014486.1\|WP_000539727.1\|3219500_3219749_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP014486.1\|WP_002183782.1\|3229516_3230845_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP014486.1\|WP_000411484.1\|3218315_3219437_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP014486.1\|WP_065212041.1\|3214297_3215296_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|183592
NZ_CP014486.1\|WP_065212039.1\|3211248_3212088_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000613875.1\|3229050_3229464_-\|ATP-synthase-subunit-I	unknown	unknown	gnl\|CDD\|377159
NZ_CP014486.1\|WP_063220401.1\|3231831_3232716_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP014486.1\|WP_065382079.1\|3219958_3220420_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP014486.1\|WP_000540452.1\|3213842_3214289_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240033
NZ_CP014486.1\|WP_063220402.1\|3226275_3227190_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP014486.1\|WP_065382077.1\|3212139_3212862_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP014486.1\|WP_065382499.1\|3227489_3227864_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000285639.1\|3230964_3231372_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133406
NZ_CP014486.1\|WP_000355451.1\|3212985_3213825_+\|DUF2785-domain-containing-protein	unknown	unknown	gnl\|CDD\|371322
NZ_CP014486.1\|WP_000945243.1\|3220697_3220841_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_000747696.1\|3227941_3228181_+\|DUF3923-family-protein	unknown	unknown	gnl\|CDD\|289806
NZ_CP014486.1\|WP_065382078.1\|3215891_3217844_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP014486.1\|WP_000938438.1\|3228303_3228852_-\|DUF2179-domain-containing-protein	gnl\|CDD\|235234	PRK04164, PRK04164, hypothetical protein; Provisional.	6.88941e-83
NZ_CP014486.1\|WP_050252092.1\|3223450_3225958_-\|collagen-like-protein	gnl\|CDD\|367362	pfam03157, Glutenin_hmw, High molecular weight glutenin subunit. Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.	2.03415e-07
NZ_CP014486.1\|WP_000539727.1\|3219500_3219749_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	4.0876e-09
NZ_CP014486.1\|WP_002183782.1\|3229516_3230845_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.47417e-160
NZ_CP014486.1\|WP_065212041.1\|3214297_3215296_-\|tryptophan--tRNA-ligase	gnl\|CDD\|183592	PRK12556, PRK12556, tryptophanyl-tRNA synthetase; Provisional.	0
NZ_CP014486.1\|WP_063220401.1\|3231831_3232716_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.57432e-18
NZ_CP014486.1\|WP_065382079.1\|3219958_3220420_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.76705e-13
NZ_CP014486.1\|WP_000540452.1\|3213842_3214289_+\|NUDIX-hydrolase	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.4897e-58
NZ_CP014486.1\|WP_063220402.1\|3226275_3227190_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.54906e-13
NZ_CP014486.1\|WP_065382077.1\|3212139_3212862_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.30353e-06
NZ_CP014486.1\|WP_000613875.1\|3229050_3229464_-\|ATP-synthase-subunit-I	gnl\|CDD\|377159	pfam03899, ATP-synt_I, ATP synthase I chain. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI. AtpI is a Ca2+/Mg2+ transporter.	1.72718e-07
NZ_CP014486.1\|WP_000285639.1\|3230964_3231372_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133406	cd04779, HTH_MerR-like_sg4, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 4). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.12621e-60
NZ_CP014486.1\|WP_000355451.1\|3212985_3213825_+\|DUF2785-domain-containing-protein	gnl\|CDD\|371322	pfam10978, DUF2785, Protein of unknown function (DUF2785). Some members in this family are annotated as hypothetical membrane spanning proteins however this cannot be confirmed. The family has no known function.	1.69702e-39
NZ_CP014486.1\|WP_000411484.1\|3218315_3219437_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.99865e-58
NZ_CP014486.1\|WP_000747696.1\|3227941_3228181_+\|DUF3923-family-protein	gnl\|CDD\|289806	pfam13061, DUF3923, Protein of unknown function (DUF3923). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 80 amino acids in length.	7.87508e-12

>NZ_CP014486.1|WP_000945243.1|3220697_3220841_+|hypothetical-protein
MLRLSDHAIKMMEQRLRIEKQRTYQANKVVDNLHHKYFFQHIFQPKR
>NZ_CP014486.1|WP_065382079.1|3219958_3220420_+|GNAT-family-N-acetyltransferase
MILKLNSTSFEVATSILQVQIPAYKVEADYLNSTAIPRLYDTVNDIQNCVETFYGYFSENKLVGFISFVQEEKLIDIHRLVVSPNFFQKGIATKLLIYIFNMFSSSMAYIVQTGKANTPAITLYKKHGFITVSDTILPDGMILTQLKKTEYTK
>NZ_CP014486.1|WP_000539727.1|3219500_3219749_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGWIITLIVGAIIGAIASSITGKNFPGGMFGNIIAGLLGASLGGKLFGTFGPSFGGIHVVPALLGAIVLIFIVSFVVKAAKK
>NZ_CP014486.1|WP_000411484.1|3218315_3219437_-|AI-2E-family-transporter
MEKINIRKRDKLRKFFREQNYLAVLLGFALLFINILLLTKISFVFTPFIVFLKTIFFPVLLAGVLFYILHPFVSLLEKKGVSRIVSIASIYLIVLGLFVFLVVTVIPIIKDQIDALIDNLPYFGHEIEQAARRFGESNLLGKIQENLNINVANMVKEYTVDFTKSLSSVTGNVTGFLSTVTEVVLTFVMVPFILFYLLKDGEQLPNHFLKFISEQRQPAAMRILDDMHYAISSYIRGQIIVSLFIGIMLLIGYLIIGIKYAVLLAILAMIVNIVPYVGPIIAITPALIIAFIDSPAMVLKVIIVMMVVQLAEGKFISPQVMGKKLDIHPITIIFIILTAGNLFGIMGIILAIPGYAILKVLVTHGYRFVKLNT
>NZ_CP014486.1|WP_065382078.1|3215891_3217844_-|hypothetical-protein
MKFIYKVGLFSFAFICFIWNAYLPSSAFAVSTSQTENKNAPLIRVLNNLGHEIDTYSMVKGNDKAMKQATDKVKSLPVNEQGNKGTIEVPEGKWNFKNEIFLPEGTTLRGKSQKTILVRSFGEFPKKPIEIIDGKEYYQGIIRMQSHTALKNITLDGEKGNEKSNPHQNGIVARGHYTEGGEATLPHESDYLKDIMIEDVVIRNITGDGITLDLIKELHIKGSKSVAVDGEKRMLVENAGNSGIIGYSIETAEIQNVVTRNIGGEDKKGKIGKNYNIALSMRKMKEPPNPGYKLQAKYPISKNVKVRDSVFIDNCYWEGLDTHSGENMEFTNNIFVGIARPIVIGGLEYRGKYYYPPKKITVEKNYINAAEHIDKWKPKNNKKSEVGIAVWGTNQTFPIEKNGKLLNPLDEGYKENIGYIKETKIMNNVIEQVEPGDDSSRFGGVALKLTEGILVENNQIGWVKSDSVKRGGIILNNSNKEFEIRGNQVGWIQKSSLITDDTKQKGHAPVEIIETGNNGTVTDNCWNENNKVGINDEKYGDYTNNKLRGIESNKWRTGKPYDENGYNYGLSKLKWDTKEGVVTGKAGKDVGSVVLKYGDTKLVETNVSNQQFTLTTDELKHGDKKFQIVARNSHINPKYRYEVHSEELIK
>NZ_CP014486.1|WP_065212041.1|3214297_3215296_-|tryptophan--tRNA-ligase
MSEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGRALYFIADYHALNAVHDSEKFSSYTKEVAATWLSLGLGEDVVFYRQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGLYTYPILMAADILLFQATHVPVGKDQIQHIEIARDIATYFNHTFGTTFTLPEYVVQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELETLFMIYKEFATEDEVQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPNLLYEALENGAEKARAIAKVNLAEIKKRIGFERER
>NZ_CP014486.1|WP_000540452.1|3213842_3214289_+|NUDIX-hydrolase
MGYIEDMRNLVGNHPLILIGSHAIILNEKDEALLQLRTDFNRWGIIGGALEYNETLEDALKREVFEETGLIIKNPELFRTYSGPDFFQIYPNGDQVHGVLVVYICREFYGELVCDQSESKELRFFSLDELPNNLPPVIEKIITDYLKK
>NZ_CP014486.1|WP_000355451.1|3212985_3213825_+|DUF2785-domain-containing-protein
MDITALQQQLELIQQNDYTQLQHIDVNELTLNMLQYIGTTDSYVRYQLIYKCFAHFIHHEFLMDDQLKLLLQTCLSDEYLYCDIYSPHTDGVFTRSYTVSLIALILQFANSHYFCTEEDIEEIKNKLITYTNLETDFRGYIENKGWAHCLAHVSDAFTEIVHNTYTTFEWYEELIHCLLNKIFIPSDLFHNNEDERIVTPLLAMLYHDFPQNDLISIIHKKIKRLPQIRKRLSLNEYCILCANIKTFLRTLFFRTKDDHNLAFTARKTERMLKELPNYY
>NZ_CP014486.1|WP_065382077.1|3212139_3212862_-|GNAT-family-N-acetyltransferase
MTTIEQLEKHFKIRRSASSIMIKENNAEIFTEEQLEEMMQYCVAEAEKDGLEKLHFEISSKSPNYDVYKKCFETYSFEYVTENMIVFKDIYEVEDVESEIDFKLIEEVGEEAFYSLWNEATGEPVAHDQFVHMMLQEIGEQWKEHCLTADVDEKPIGIVIPHIERGTLEEGKLMYFAVTPNMRNKGYEAALFAGAMFVLKEIGASYYIGETNIQNEWMKDVFEKNGCQLFSSTERYVRKF
>NZ_CP014486.1|WP_065212039.1|3211248_3212088_-|hypothetical-protein
MLKQSMHSFVLLYPNVLLEGWNVEKVSERYEGEKWGTFWFQVVTPTGMFRVKEFFLDIMEPVFPDSCISQAKGDCFQYKGLVYWKGINYKGKESYVTSIWKTQVEISVDHGYVNQDEMERFLFELQPVNMELGKTILHTSFHLLSFQAKRSEMGEIGRCREWNAPDDVSYVNLLIHEKLNWKLESVGFGNDEMQYVYWDEVNKLYALWVCRHKNKAYYPISSWTMNYGPKQIINGLEFYSHPNRGTVVYEDLGNEQIAYVFRGNPCTNFEQVKELFACL
>NZ_CP014486.1|WP_050252092.1|3223450_3225958_-|collagen-like-protein
MRHHRKCKKFGVALPLPLIGATGPTGNSGPIGPTGGHEGPVGPTGVTGPTGATGPQGPQGIRGIQGPRGTTGAQGIQGVIGDTGEQGITGPTGLQGAQGLIGNQGLIGDIGVQGLEGIQGATGPAGSQGIQGIQGIQGEIGERGQTGAQGMQGERGVTGVSGVTGPQGPQGVQGIQGEQGAIGIQGEDGFQGIQGITGEEGPQGAQGIQGEVGPTGSTGMQGAQGISGIKGITGVIGLQGPQGVQGIQGITGATGFQGIKGIRGITGATGSIGTQGSEGPPGGPTGVTGPIGPSSGVTGPAGPPGPPGGPTGPTGATGSTGVSGGIGPIGGQGVQGITGPTGHQGVRGAQGAQGVVGAVGVQGAQGPQGNQGITGPTGAEGSQGIQGPLGVTGPTGAEGPKGIQGIQGVIGPTGAQGMVGIQGIAGPVGVTGAEGAQGAQGIRGATGPAGAQGIQGVQGIQGETGAAGTQGPQGVQGIQGTTGLTGTQGAQGPQGVQGIIGPTGAIGLQGPQGLQGITGPTGAQGVQGIQGVQGIIGPTGAQGIRGPQGNTGEVGITGPQGVQGAQGSQGPQGPQGNVGITGATGETGATGATGATGPQGVQGVQGITGIQGITGTTGNTGATGPQGIQGIQGIQGLQGPIGASGVTGASGSIGPVGAQGSQGPSGVVGPTGATGSAGSIGFFGIAGATGATGLPSGGGYFFSTSTSTIAANALIPINSGSTVFGSDVSLTNATTVTLSTPGIYLVSYYFQGDPTAGNETISVRLTLNGTQVAGSFIFYVTGGTFILEPAVSNTMVIEVTSSNATLSLQNGPLAIGHVTTLSGVITASLNVLKIV
>NZ_CP014486.1|WP_063220402.1|3226275_3227190_-|tetratricopeptide-repeat-protein
MNINEKAIEMFEQNKYEEAMELFQQAVHESRDVQSLNNLAWMYFYEEENDDKALELIREVVKFNPSSYFPYNILGDIYMKQEKWTEAKEALQKSISIQPSDEAYHNVAVAHYNLGELEKASDFFLRVAGDSDYIMYSYVKCLIDLERTTEAKEKLDTFNRESDNFLGEINVADLYVELNCYKEAIEWFEKGYKECWKSPNWIGRFVYALYKTNNFSRINEVIRECIEAKTAEIEDVQNEEVEENWTENDKKELIEEYTEENNCYKTMVERIKSGYVPGLEFETDFIGGCYLFGCKRHNHLEYEQ
>NZ_CP014486.1|WP_065382499.1|3227489_3227864_+|hypothetical-protein
MKQKLLVLLFTGIILSGCSTIAENSLESGKGSMELLTPTITAKDNELEIKTKGIDENKVTFIYVANKKVLEQKLKNGESYKLNIKDIEHAHRTDYKPKVQLLQTKDDDDGEIVTFKQVRYTVKN
>NZ_CP014486.1|WP_000747696.1|3227941_3228181_+|DUF3923-family-protein
MKKRWISWWIGNLFWIIVFGIWAAIIWLREVDGAGVIQTPEIKSISLIVLLITFIIPVFFQIIWLIINLRMSKKHNYTI
>NZ_CP014486.1|WP_000938438.1|3228303_3228852_-|DUF2179-domain-containing-protein
MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAGVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDEHAS
>NZ_CP014486.1|WP_000613875.1|3229050_3229464_-|ATP-synthase-subunit-I
MIQEALRVYRLQLYVIFSGLLLMWTITPFGKQVTGFGIGLAVSAYCLWLLARRVEKLGKSIVMKEKAPGLGVLNRFAAAILGAIIMYEIEHEMEMWAFGTGILGGHFLMIANLAYANMQLVKEEEKQREHASKDIEL
>NZ_CP014486.1|WP_002183782.1|3229516_3230845_-|HlyC/CorC-family-transporter
MEIFNLVMVAILIAFTGFFVAAEFAIVKIRSSRIDQLVAEGKRGALAAKKVTTNLDEYLSACQLGITVTAMGLGWLGEPTIEKLLHPLFEKWNLNPSISSVLTFGLAFMIMTYLHVVVGELAPKTMAIQKAERVTLLLAGPLMMFYKIMYPFIWVLNGSARVITGLFGLKPASEHEVAHTEEELRLILSDSYESGEINQAEYKYVNNIFEFDNRIAKEIMVPRTEIVGFYLEDSVEEHMKVIQNERYTRYPIFGEDKDDIIGMVNVKDFFIRYMTEDQKDLSSIRSYMRPIIEVMETTPIHDLLLQMQKKRIPMAVLYDEYGGTAGIVTLEDILEEIVGEIRDEYDEDEAPPIQHVNEQHIIVDGKVLISEVKDLFGLHIEEDDVDTIGGWIMMQNHEIEEGQHVEAEGYEFKVLEKDAYQIKRVEIRKMEQEQEEEKAATV
>NZ_CP014486.1|WP_000285639.1|3230964_3231372_-|MerR-family-transcriptional-regulator
MYRIGQLALMAHVSKRTIDYYTNLGILKAERSQSNYRYYDETAFETLQFIEKCKEMHMPLCEIKEKIEEKKKLLGINEHVSKQVNEVTDHIHRLEVELTELKPLLDELTDSQREKISKSLSGQTTALIQTLALLL
>NZ_CP014486.1|WP_063220401.1|3231831_3232716_+|DMT-family-transporter
MKQTILGAICLSLAASIWGGMYVVSKYVLDFIPPLTLVWLRFIIAFVVLYGILKLAEKKQKKKVTLRKKDWLLFAWIGFIGYFISITCQFIGTKLSDAHTGSLVTSATPAFMIIFAALILKEKLTARRLLSTIIATIGVIIVIGWDIEIGSYFIGTIILVGAAITWALLSIYVKIASIQFSSLVITTYAIFFSLFFITPFMIWELQAASIGTVNTYVILGVLYLGIVSTAGAFFLWNKGLELLDASIGSLFFFFQPIVGSLLGWLLLNETLNSNFFIGGILIICSVLITTFEKK
>NZ_CP014486.1|WP_000350943.1|3232735_3233272_-|hypothetical-protein
MDIFQYLEEMQEDVFSLAVEQIEAKYYDICCMLASTEYAERIKVIDVESYKVSIRVGLDAAVEMATNEEAKAIYFEYDLDNEWTSQFYICEEYAPLEEEDDDWASEWTYDVEGPESVELADMYNENGFDTSEKAIGITLYLIAKTLCSFISVRSEVQNNIPICIGFHDQDPIMRTGRD

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Crispr_ID: NZ_CP014486_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014486_4

5114388-5114521

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP014486_4

>merge|NZ_CP014486|4|5114388-5114521|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGGTTCTTCTTTTTTGTCACTAGTTGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP014486|4|2|5114388-5114521|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGG	TTCTTCTTTTTTGTCACTAGTTGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014486.1\|WP_000008901.1\|5114065_5114200_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014486.1\|WP_063220195.1\|5117136_5118144_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP014486.1\|WP_000544012.1\|5113484_5113757_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP014486.1\|WP_000568229.1\|5125030_5126893_-\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
NZ_CP014486.1\|WP_000931959.1\|5111457_5111892_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP014486.1\|WP_065381924.1\|5123531_5125034_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP014486.1\|WP_000411274.1\|5119470_5120775_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP014486.1\|WP_002042039.1\|5120814_5121525_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP014486.1\|WP_000457978.1\|5112322_5113324_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP014486.1\|WP_065381929.1\|5106036_5106723_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|376775
NZ_CP014486.1\|WP_000672662.1\|5118244_5119264_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP014486.1\|WP_072770168.1\|5122009_5123530_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP014486.1\|WP_065381926.1\|5108742_5109444_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP014486.1\|WP_000170866.1\|5116113_5116956_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP014486.1\|WP_047792181.1\|5115409_5116114_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP014486.1\|WP_000057889.1\|5121570_5121807_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP014486.1\|WP_065381925.1\|5109433_5110177_-\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP014486.1\|WP_065381928.1\|5106740_5107622_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP014486.1\|WP_000467956.1\|5110435_5111113_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP014486.1\|WP_065381927.1\|5107862_5108630_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870

Protein	Function_ID	Function_description	E-value
NZ_CP014486.1\|WP_063220195.1\|5117136_5118144_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.41339e-31
NZ_CP014486.1\|WP_000544012.1\|5113484_5113757_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP014486.1\|WP_000568229.1\|5125030_5126893_-\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP014486.1\|WP_000931959.1\|5111457_5111892_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP014486.1\|WP_065381924.1\|5123531_5125034_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	2.26767e-177
NZ_CP014486.1\|WP_000411274.1\|5119470_5120775_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP014486.1\|WP_002042039.1\|5120814_5121525_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	3.8296e-34
NZ_CP014486.1\|WP_000170866.1\|5116113_5116956_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.20989e-89
NZ_CP014486.1\|WP_065381929.1\|5106036_5106723_-\|sugar-transferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	5.65602e-98
NZ_CP014486.1\|WP_000672662.1\|5118244_5119264_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	4.7774e-134
NZ_CP014486.1\|WP_072770168.1\|5122009_5123530_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	1.83293e-151
NZ_CP014486.1\|WP_065381926.1\|5108742_5109444_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.28723e-83
NZ_CP014486.1\|WP_000457978.1\|5112322_5113324_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP014486.1\|WP_047792181.1\|5115409_5116114_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	8.58216e-05
NZ_CP014486.1\|WP_000057889.1\|5121570_5121807_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	1.23409e-23
NZ_CP014486.1\|WP_065381925.1\|5109433_5110177_-\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	9.26333e-85
NZ_CP014486.1\|WP_065381928.1\|5106740_5107622_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP014486.1\|WP_000467956.1\|5110435_5111113_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.20652e-81
NZ_CP014486.1\|WP_065381927.1\|5107862_5108630_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.56114e-106

>NZ_CP014486.1|WP_000008901.1|5114065_5114200_-|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEEFEREE
>NZ_CP014486.1|WP_000544012.1|5113484_5113757_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP014486.1|WP_000457978.1|5112322_5113324_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP014486.1|WP_000931959.1|5111457_5111892_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP014486.1|WP_000467956.1|5110435_5111113_-|CpsD/CapB-family-tyrosine-protein-kinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHVRSIIVTSADPGDGKTTTISNLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKLLGVVLNDKREEKEQYGYY
>NZ_CP014486.1|WP_065381925.1|5109433_5110177_-|capsular-biosynthesis-protein
MEETINLKELFHILKKRLAMILVIAFGAAIVSAIFSFFIMTPIYQSSTQILVNQKKQEGTAIQFNEVQTNIQLTNTYKVIIKSPVILDQVKEKLGLNITTQELNKQIEVTNEKDSQVVLVTTKDKNPKMARDIANTTAEVFKNEVAKIMSIDNVTVLSKAEIVEKQAPIKPNPMLNIIIAFVVGLIASVGMAFLLEYLDNTVKKEEDVEKVLGLPVLGIVARMDEETMNVKSHAPSSRKVRGQTIGS
>NZ_CP014486.1|WP_065381926.1|5108742_5109444_-|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAVDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQLDNIFGLTNVLTNSERLEKCIQATSVDNLGFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDLPPILAVTDAQIMANVCDASILVVRSEATEKETAVKAKGLLESAKGKLLGVVLNDREREEGLYYYYGAN
>NZ_CP014486.1|WP_065381927.1|5107862_5108630_-|tyrosine-protein-phosphatase
MIDLHCHILPGIDDGAQTVTDSLVMAQQAVSEGIHTIVATPHHQNGKYINERTSIIHEVKQLNDALQQHNIPLTILPGQEVRLYGDLLEDYEAGKVVTLNETNKYIFIEFPSNHVPRYAEQLLYELRVKGMVPIIVHPERNAELIERPDKLYNLVNKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMVASDAHNTTSRGFYLAESYELIEKEFGMNVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP014486.1|WP_065381928.1|5106740_5107622_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQSLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPVEKNDRRYQVRQFVEKPAQGTAPSNLAIMGRYVLTPEIFMFLDNQQKGAGGEIQLTDAIQRLNEIQRVFAYDFEGIRYDVGEKFGFIKTTIEMALQHEELKDELIEYMNEILVQKNVYI
>NZ_CP014486.1|WP_065381929.1|5106036_5106723_-|sugar-transferase
MTLVKMPSEGIKKENSLVVDLEKLNKRKGYWIVKRCIDCIGALCGILLLFPVFLIVSLMIKYEDPKGPVLFKQIRVGRNGKEFNMYKFRSMVTDAEERLNDILKYNEVSGAMFKMKEDPRVTKIGKFIRKTSLDELPQLINVLKGEMSLVGPRPPLVREVREYDSYDMQRLMIVPGCTGLWQVSGRSSLSFKDMVELDITYINKMSFLFDLIIIFKTFNVIMGDKDAY
>NZ_CP014486.1|WP_047792181.1|5115409_5116114_-|ABC-transporter-permease
MTFSMRRVSAIFRKEVQDFKTNSQVLLMAFLPIILSFLFSRFGVGKEMLGITTITAFLFVAGFVQSMVIAEEKEKHTLRVLMLSPASSVEVLLGKSLLTSGLTMVICIANLFILDQLNINLPLVGLIFLCGTILFIVLGTMIGLLASSVPQTSIIGMPILMTMYLAVQFEPMVENKVIKTMIGYLPTSHIVKALKSLVGGSGFSSISGHVLNVAVWLIISLVVCLIVYKKKQLD
>NZ_CP014486.1|WP_000170866.1|5116113_5116956_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFSGKTALRNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLTQVNLLDDKKTPVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNEEGTTIFLTTHNMDEAETLCNRIAFLCGGEIVALDTPENLRLQYAKDQIEVVLKGKRKEVVQKDELGANRISEWMKKGELLSIHSHEPTLGDIFIEVTGRGL
>NZ_CP014486.1|WP_063220195.1|5117136_5118144_-|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein
MALLELKQLGKANQLPEMELKVEKGQCIVLQCNNHTAKVLHRIIIGQEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYESKISIEEVVQSVGLLDKLNVKVEKLSFSEKRRLHIGRVMIHNPDLIILEEPEQNVDIESTVIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKVEIEQEEVEEVDEEKVVQIIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLGELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP014486.1|WP_000672662.1|5118244_5119264_-|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVETLPVEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGGKKNNADVTDTVKDQVYKSKDELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVAIKTMNDYEGKLMVKK
>NZ_CP014486.1|WP_000411274.1|5119470_5120775_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVAATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVNFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP014486.1|WP_002042039.1|5120814_5121525_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVLFLVGYREMKPISDEHKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKEKANIQKWEVEQSPDGYKATSYKKLSSYEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQNMNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP014486.1|WP_000057889.1|5121570_5121807_-|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMKSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP014486.1|WP_072770168.1|5122009_5123530_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLFSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKSRASNEAAMKYVISGGIGTAITLFGMSYLYGITGSTNIVDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGATTPVTAFLGTISKIAGFLLIIRLFLMIFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNIKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQNDEENITIFTGLYKRSPFTAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP014486.1|WP_065381924.1|5123531_5125034_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAIVLACTYASGKNLSLFDEKMKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLATLAAIAAFSIKRNLKAFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIIFSILFAKTGTTNIVELKEILRSVNAEGALVIPGSLQLSVFIAIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDVATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLASLNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSDITALGGLAKSVPVLSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK
>NZ_CP014486.1|WP_000568229.1|5125030_5126893_-|NADH-quinone-oxidoreductase-subunit-L
MIDYAWLIPLFPLVSFLLLIIFGKKIREGSSVLSIFFVFLSFILAVLVLIERFSEASVKHKWVWLRAGDVDISFGFEVTALGALMLFIVTLVSLLVHVYSKGYMKGDERLPTFYAYLGLFTFAMLGLVISTNLLQLYIFWELVGLGSFLLIGFYFFKEEAKAAAKKAFIMTRIGDVGLFIGMILIFWYAGSFEYDAIFRAIYTGDLPPYMITITAILIFIGAMGKSGQFPLHTWLPDAMEGPTPVSALIHAATMVAAGVYLVATMFPLFSASTVAMQTVAIVGAFTAIFAASIGLVQTDIKRVLAYSTVSQLGYMMLALGSAGYVAGIFHLTTHAFFKALLFLAAGSVIHAVHTQNINKMGGLQKKMKVTGTLFLIGTLAISGVPLLSGFFSKDEILAATWMNGNYVLFTLAVIAAFLTAFYMFRLYFLVFTGETKTKEEVHESPRVMTYPMIVLGVLAVVAGYINTPWFGTFLGDWLTKDVGFKVEETHGPVWIMIVATLVSFAGIALAYFIYRKKSISRNWAGGTETSLYNLLKEKYYVDELYNMTVIPITKGIAHVLRLFEVYVVEGIAVLIASVVKGTSNLGSKLQNGNVQVYGTVTAVSLAVLVIILLYTGGDLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014486_4	4.1\|5114411\|31\|NZ_CP014486\|CRISPRCasFinder	5114411-5114441	31	JX238501	Bacillus phage phiAGATE, complete genome	124559-124589	8	0.742
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	9	0.735
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47181-47214	11	0.676
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47565-47598	11	0.676
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47949-47982	11	0.676
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48333-48366	11	0.676
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48717-48750	11	0.676
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49101-49134	11	0.676
NZ_CP014486_4	4.2\|5114465\|34\|NZ_CP014486\|CRISPRCasFinder	5114465-5114498	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49485-49518	11	0.676

1. spacer 4.1|5114411|31|NZ_CP014486|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

ttcttcttttttgtcactagttgaaccgctt	CRISPR spacer
ctaaccttttttgccactagttaaaccgccc	Protospacer
.*  .********.********.******..

2. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

3. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

4. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

5. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

6. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

7. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

8. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

9. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

10. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

11. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

12. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

13. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

14. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

15. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

16. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

17. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

18. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

19. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

20. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

21. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

22. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

23. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

24. spacer 4.2|5114465|34|NZ_CP014486|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

257610 : 265559

uncultured_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000917311.1\|257610_257895_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8
WP_065382431.1\|257933_259568_+	chaperonin GroEL	A0A219YK78	uncultured_virus	3.4e-157	57.8
WP_162840109.1\|259971_261513_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	8.9e-22	31.7
WP_000833082.1\|261897_263223_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	6.4e-45	30.1
WP_000929885.1\|263368_264070_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.3e-40	36.9
WP_000719223.1\|264053_265559_+	aminopeptidase AmpS	W8CYF6	Bacillus_phage	5.4e-32	30.3

DBSCAN-SWA_2

311132 : 319508

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625682.1\|311132_312440_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.3
WP_001170544.1\|312528_313248_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000278823.1\|313240_313495_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666774.1\|313491_314175_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_065382292.1\|314158_316378_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.6e-163	41.2
WP_000879025.1\|316362_317778_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-55	35.4
WP_001262439.1\|317883_318924_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.9
WP_000088589.1\|318920_319508_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.1e-28	37.4

DBSCAN-SWA_3

654701 : 662659

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_139256957.1\|654701_655664_-	WYL domain-containing protein	A0A1B0RXM1	Streptococcus_phage	4.1e-17	29.4
WP_065381813.1\|655759_656281_+	dihydrofolate reductase	NA	NA	NA	NA
WP_072770181.1\|656294_657686_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.6e-33	29.5
WP_006918011.1\|657697_658375_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-32	35.6
WP_065382252.1\|658550_659798_+	ArsR family transcriptional regulator	NA	NA	NA	NA
WP_065382253.1\|659931_660462_+	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	6.6e-17	35.0
WP_000831286.1\|660474_660819_+	DUF4064 domain-containing protein	A0A0S2MVJ2	Bacillus_phage	8.5e-42	78.1
WP_065382254.1\|661207_662659_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	1.9e-138	53.6

DBSCAN-SWA_4

1874989 : 1883637

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063219865.1\|1874989_1876237_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.3e-11	31.8
WP_065382155.1\|1876336_1877101_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_065382156.1\|1877341_1879102_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.3e-274	98.4
WP_025710347.1\|1879187_1879865_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.3e-122	98.7
WP_139256975.1\|1879861_1880935_+	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	3.3e-185	96.9
WP_065382415.1\|1880959_1881553_-	DUF3139 domain-containing protein	NA	NA	NA	NA
WP_000818985.1\|1881743_1882463_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_065382416.1\|1882764_1883637_+	aminoglycoside 6-adenylyltransferase	A0A1X9I6F2	Streptococcus_phage	4.3e-66	44.7

DBSCAN-SWA_5

3559738 : 3569905

Bacillus_phage(54.55%)

bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000413738.1\|3559738_3560359_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	8.2e-19	62.2
WP_000976237.1\|3560449_3561253_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_000031383.1\|3561253_3561796_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_001102628.1\|3561788_3562112_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_000392444.1\|3562483_3562714_-\|bacteriocin	bacteriocin biosynthesis protein	A0A1B1P7Q9	Bacillus_phage	1.5e-23	73.7
WP_000405767.1\|3562775_3563672_-	N-acetylmuramoyl-L-alanine amidase family protein	A0A0S2MVR5	Bacillus_phage	4.1e-80	52.4
WP_001051368.1\|3563946_3564789_-	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	6.1e-33	47.7
WP_033692154.1\|3564907_3565894_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.7e-34	43.9
WP_000464425.1\|3566132_3566519_-	DUF1492 domain-containing protein	A0A288WG73	Bacillus_phage	2.6e-47	71.4
WP_000511420.1\|3566637_3567510_-	DnaD domain protein	A0A2H4J394	uncultured_Caudovirales_phage	6.8e-96	65.3
WP_001189065.1\|3567662_3567857_-	hypothetical protein	A0A1C8E9A1	Bacillus_phage	1.7e-15	71.0
WP_063220698.1\|3567868_3568627_-	ORF6C domain-containing protein	A0A2H4JBC7	uncultured_Caudovirales_phage	1.2e-96	69.0
WP_000283431.1\|3568829_3569042_-	hypothetical protein	A6M975	Geobacillus_virus	1.6e-11	63.0
WP_011110319.1\|3569245_3569905_+	helix-turn-helix domain-containing protein	A0A2H4J441	uncultured_Caudovirales_phage	4.3e-34	41.0

DBSCAN-SWA_6

4403052 : 4410738

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065382217.1\|4403052_4403976_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-45	43.5
WP_065382216.1\|4404101_4405037_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	9.2e-22	24.7
WP_000018035.1\|4405038_4405731_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_001293578.1\|4405899_4406073_+	hypothetical protein	NA	NA	NA	NA
WP_065382215.1\|4406073_4406268_+	YwbE family protein	NA	NA	NA	NA
WP_065382214.1\|4406306_4407506_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.0e-70	41.0
WP_000587818.1\|4407801_4408125_+	heme oxygenase	NA	NA	NA	NA
WP_001086126.1\|4408197_4408962_-	class B sortase	NA	NA	NA	NA
WP_000403758.1\|4408994_4409765_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.7e-13	27.1
WP_001036848.1\|4409754_4410738_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	27.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP014487

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP014486

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection