CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP014431	Staphylococcus aureus strain USA300-SUR19 plasmid pUSA04-1-SUR19, complete sequence	0 crisprs	csa3	0	0	2
NZ_CP014430	Staphylococcus aureus strain USA300-SUR19 plasmid pUSA01-1-SUR19, complete sequence	0 crisprs	NA	0	0	0
NZ_CP014429	Staphylococcus aureus strain USA300-SUR19 chromosome, complete genome	9 crisprs	cas3,DEDDh,DinG,csa3,WYL	8	4	9

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 11744

Streptococcus_phage(50.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000627289.1\|1237_1768_+	streptothricin N-acetyltransferase Sat4	A0A1B0RXL7	Streptococcus_phage	1.3e-89	97.8
WP_001096887.1\|1860_2655_+	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_001105991.1\|3670_4345_-\|transposase	IS6-like element IS257 family transposase	A0A0N9SKD3	Staphylococcus_phage	6.8e-128	99.6
WP_001037130.1\|4606_4792_+	hypothetical protein	NA	NA	NA	NA
WP_000690637.1\|5014_5593_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	4.9e-42	51.7
WP_000182645.1\|5856_6237_-	penicillinase repressor BlaI	NA	NA	NA	NA
WP_001096381.1\|6226_7984_-	beta-lactam sensor/signal transducer BlaR1	NA	NA	NA	NA
WP_000733287.1\|8090_8936_+	penicillin-hydrolyzing class A beta-lactamase BlaZ	A0A1B0VBP7	Salmonella_phage	5.7e-31	34.0
WP_000418035.1\|9461_9881_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000481279.1\|10004_10976_+	oxidoreductase	NA	NA	NA	NA
WP_001791613.1\|11147_11240_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_000119690.1\|11396_11744_-	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	4.9e-13	36.8

DBSCAN-SWA_2

18043 : 25882

Staphylococcus_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000797248.1\|18043_18229_-	helix-turn-helix transcriptional regulator	A0A142LP09	Marinitoga_camini_virus	9.9e-05	37.9
WP_001049146.1\|18233_18572_-	hypothetical protein	NA	NA	NA	NA
WP_000583528.1\|18817_19426_-	recombinase family protein	G8I4U3	Mycobacterium_phage	1.0e-13	30.2
WP_000196697.1\|19911_20811_-	Mph(C) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_000438874.1\|20909_22376_-	ABC-F type ribosomal protection protein Msr(A)	A0A2I4R674	Erysipelothrix_phage	6.6e-67	37.7
WP_001105960.1\|22849_23524_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	1.7e-126	97.3
WP_000793446.1\|24952_25882_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.0e-41	42.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP014429

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014429_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_1

433391-433491

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014429_1

>merge|NZ_CP014429|1|433391-433491|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NZ_CP014429|1|1|433391-433491|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_000052781.1\|429245_429815_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_CP014429.1\|WP_001789518.1\|432615_432717_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000394698.1\|434581_435244_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000158371.1\|425350_425932_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP014429.1\|WP_000930486.1\|427706_429230_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_CP014429.1\|WP_001289311.1\|430306_431062_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NZ_CP014429.1\|WP_000868248.1\|425997_426381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000763768.1\|435386_435794_-\|general-stress-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP014429.1\|WP_000466748.1\|424673_424925_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP014429.1\|WP_000551776.1\|441335_441872_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000424966.1\|439681_441223_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP014429.1\|WP_000991007.1\|431142_432531_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP014429.1\|WP_000421410.1\|436306_436885_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP014429.1\|WP_000264071.1\|438190_439657_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_CP014429.1\|WP_000159787.1\|443367_443640_-\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP014429.1\|WP_000793009.1\|436884_438153_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP014429.1\|WP_000041883.1\|442264_442969_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP014429.1\|WP_000746687.1\|426635_427262_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP014429.1\|WP_000956132.1\|433507_434464_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_CP014429.1\|WP_000211676.1\|424963_425173_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_000052781.1\|429245_429815_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NZ_CP014429.1\|WP_000466748.1\|424673_424925_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
NZ_CP014429.1\|WP_000264071.1\|438190_439657_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_CP014429.1\|WP_000158371.1\|425350_425932_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	7.98269e-49
NZ_CP014429.1\|WP_000930486.1\|427706_429230_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_CP014429.1\|WP_001289311.1\|430306_431062_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
NZ_CP014429.1\|WP_000763768.1\|435386_435794_-\|general-stress-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
NZ_CP014429.1\|WP_000424966.1\|439681_441223_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP014429.1\|WP_000991007.1\|431142_432531_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP014429.1\|WP_000421410.1\|436306_436885_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
NZ_CP014429.1\|WP_000159787.1\|443367_443640_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
NZ_CP014429.1\|WP_000793009.1\|436884_438153_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
NZ_CP014429.1\|WP_000041883.1\|442264_442969_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
NZ_CP014429.1\|WP_000746687.1\|426635_427262_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
NZ_CP014429.1\|WP_000956132.1\|433507_434464_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442

>NZ_CP014429.1|WP_001789518.1|432615_432717_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNSVVIGGKGK
>NZ_CP014429.1|WP_000991007.1|431142_432531_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>NZ_CP014429.1|WP_001289311.1|430306_431062_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_CP014429.1|WP_000052781.1|429245_429815_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_CP014429.1|WP_000930486.1|427706_429230_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_CP014429.1|WP_000746687.1|426635_427262_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_CP014429.1|WP_000868248.1|425997_426381_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>NZ_CP014429.1|WP_000158371.1|425350_425932_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYDKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>NZ_CP014429.1|WP_000211676.1|424963_425173_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFNPILSTFSNIIIHIDHFHANKKDDN
>NZ_CP014429.1|WP_000466748.1|424673_424925_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>NZ_CP014429.1|WP_000956132.1|433507_434464_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_CP014429.1|WP_000394698.1|434581_435244_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_CP014429.1|WP_000763768.1|435386_435794_-|general-stress-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>NZ_CP014429.1|WP_000421410.1|436306_436885_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NZ_CP014429.1|WP_000793009.1|436884_438153_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_CP014429.1|WP_000264071.1|438190_439657_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_CP014429.1|WP_000424966.1|439681_441223_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_CP014429.1|WP_000551776.1|441335_441872_-|hypothetical-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>NZ_CP014429.1|WP_000041883.1|442264_442969_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>NZ_CP014429.1|WP_000159787.1|443367_443640_-|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP014429_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_2

672550-672642

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014429_2

>merge|NZ_CP014429|2|672550-672642|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>NZ_CP014429|2|2|672550-672642|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_000808902.1\|663236_664175_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP014429.1\|WP_000655099.1\|669034_669142_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_001018677.1\|678981_679356_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP014429.1\|WP_001222133.1\|677057_677774_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000362967.1\|675453_676254_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP014429.1\|WP_000735558.1\|676389_676896_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000477504.1\|665090_665567_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP014429.1\|WP_001790232.1\|673745_674696_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP014429.1\|WP_001200748.1\|667949_668960_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_CP014429.1\|WP_000633782.1\|664385_664922_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP014429.1\|WP_000365354.1\|674750_675470_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP014429.1\|WP_000180230.1\|665606_666902_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP014429.1\|WP_001021145.1\|669647_671309_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP014429.1\|WP_000901764.1\|671696_672332_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP014429.1\|WP_001788287.1\|666929_667451_+\|YwhD-family-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP014429.1\|WP_000746375.1\|681588_682092_-\|transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP014429.1\|WP_077442703.1\|681071_681608_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP014429.1\|WP_001045421.1\|677942_678731_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP014429.1\|WP_000749059.1\|672710_673598_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP014429.1\|WP_000359086.1\|669234_669651_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_000808902.1\|663236_664175_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NZ_CP014429.1\|WP_001018677.1\|678981_679356_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_CP014429.1\|WP_000362967.1\|675453_676254_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
NZ_CP014429.1\|WP_077442703.1\|681071_681608_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.55456e-53
NZ_CP014429.1\|WP_000477504.1\|665090_665567_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP014429.1\|WP_001790232.1\|673745_674696_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NZ_CP014429.1\|WP_001200748.1\|667949_668960_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP014429.1\|WP_000633782.1\|664385_664922_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NZ_CP014429.1\|WP_000365354.1\|674750_675470_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP014429.1\|WP_000180230.1\|665606_666902_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_CP014429.1\|WP_001021145.1\|669647_671309_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP014429.1\|WP_000901764.1\|671696_672332_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NZ_CP014429.1\|WP_001788287.1\|666929_667451_+\|YwhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP014429.1\|WP_000746375.1\|681588_682092_-\|transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	2.373e-09
NZ_CP014429.1\|WP_001045421.1\|677942_678731_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
NZ_CP014429.1\|WP_000749059.1\|672710_673598_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
NZ_CP014429.1\|WP_000359086.1\|669234_669651_+\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58

>NZ_CP014429.1|WP_000901764.1|671696_672332_+|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP014429.1|WP_001021145.1|669647_671309_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP014429.1|WP_000359086.1|669234_669651_+|DUF1934-domain-containing-protein
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP014429.1|WP_000655099.1|669034_669142_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NZ_CP014429.1|WP_001200748.1|667949_668960_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP014429.1|WP_001788287.1|666929_667451_+|YwhD-family-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP014429.1|WP_000180230.1|665606_666902_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP014429.1|WP_000477504.1|665090_665567_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP014429.1|WP_000633782.1|664385_664922_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP014429.1|WP_000808902.1|663236_664175_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>NZ_CP014429.1|WP_000749059.1|672710_673598_+|ABC-transporter-substrate-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP014429.1|WP_001790232.1|673745_674696_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP014429.1|WP_000365354.1|674750_675470_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP014429.1|WP_000362967.1|675453_676254_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP014429.1|WP_000735558.1|676389_676896_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP014429.1|WP_001222133.1|677057_677774_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP014429.1|WP_001045421.1|677942_678731_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>NZ_CP014429.1|WP_001018677.1|678981_679356_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP014429.1|WP_077442703.1|681071_681608_-|IS30-family-transposase
MGSKSINNREEFGHYEIDTVWSVRPSTYCLLTIIERKTRYLYASRLNTRKSNVVCNEIINIMKPLLPKSITMDRGKEFALFEEIEDELNCSIYFSDLGCPYQRGSIENANGLLRQYYPKGTDFANITQKSLDEAVKQINARPRMIFDYKSSEEMLKYHVSTQNCEPILNDCVRHEPVN
>NZ_CP014429.1|WP_000746375.1|681588_682092_-|transposase
MKKRKKRKELDYKTRLAIAKYLNDGLNIIQISKILGRDDAVLYREVNKRSVDGVYNPLLAEEDAIKSRSISDEQVAKRRRLNDETKAYIEEKLSLKWSPRQIASQIEKDTGYYISYPTIYRYIRNGLVKVDVKRDMRQAGKKYNKSSEKRGKLDVGSRVIKYRLKKY

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Crispr_ID: NZ_CP014429_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_3

848360-848445

Unclear

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014429_3

>merge|NZ_CP014429|3|848360-848445|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NZ_CP014429|3|3|848360-848445|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_000662675.1\|839770_842617_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP014429.1\|WP_000749380.1\|835612_836452_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP014429.1\|WP_000638419.1\|837272_837509_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP014429.1\|WP_000654030.1\|856231_857245_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP014429.1\|WP_000816295.1\|853238_854141_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP014429.1\|WP_001248939.1\|849785_850781_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP014429.1\|WP_000369722.1\|848877_849789_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP014429.1\|WP_000057551.1\|845556_846996_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP014429.1\|WP_000513308.1\|844216_845056_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP014429.1\|WP_001224793.1\|845063_845549_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP014429.1\|WP_001074749.1\|858446_859637_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP014429.1\|WP_001260089.1\|859758_860520_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP014429.1\|WP_000279414.1\|857297_858308_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP014429.1\|WP_000070826.1\|854842_855472_+\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP014429.1\|WP_000006556.1\|850890_851835_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP014429.1\|WP_000134963.1\|847062_847998_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP014429.1\|WP_000538141.1\|836625_837276_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP014429.1\|WP_000229253.1\|837777_839763_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP014429.1\|WP_000958224.1\|843278_844211_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP014429.1\|WP_001049165.1\|852408_852996_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_000662675.1\|839770_842617_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP014429.1\|WP_000749380.1\|835612_836452_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
NZ_CP014429.1\|WP_000638419.1\|837272_837509_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP014429.1\|WP_000654030.1\|856231_857245_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_CP014429.1\|WP_000816295.1\|853238_854141_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
NZ_CP014429.1\|WP_001248939.1\|849785_850781_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP014429.1\|WP_000369722.1\|848877_849789_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP014429.1\|WP_000057551.1\|845556_846996_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.28078e-06
NZ_CP014429.1\|WP_000513308.1\|844216_845056_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
NZ_CP014429.1\|WP_001224793.1\|845063_845549_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP014429.1\|WP_001074749.1\|858446_859637_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP014429.1\|WP_001260089.1\|859758_860520_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
NZ_CP014429.1\|WP_000279414.1\|857297_858308_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP014429.1\|WP_000070826.1\|854842_855472_+\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
NZ_CP014429.1\|WP_000006556.1\|850890_851835_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	2.25668e-152
NZ_CP014429.1\|WP_000134963.1\|847062_847998_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP014429.1\|WP_000538141.1\|836625_837276_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP014429.1\|WP_000229253.1\|837777_839763_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP014429.1\|WP_000958224.1\|843278_844211_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP014429.1\|WP_001049165.1\|852408_852996_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148

>NZ_CP014429.1|WP_000134963.1|847062_847998_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP014429.1|WP_000057551.1|845556_846996_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP014429.1|WP_001224793.1|845063_845549_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP014429.1|WP_000513308.1|844216_845056_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP014429.1|WP_000958224.1|843278_844211_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP014429.1|WP_000662675.1|839770_842617_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEHDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP014429.1|WP_000229253.1|837777_839763_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP014429.1|WP_000638419.1|837272_837509_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP014429.1|WP_000538141.1|836625_837276_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP014429.1|WP_000749380.1|835612_836452_+|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP014429.1|WP_000369722.1|848877_849789_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP014429.1|WP_001248939.1|849785_850781_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP014429.1|WP_000006556.1|850890_851835_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVEEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP014429.1|WP_001049165.1|852408_852996_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP014429.1|WP_000816295.1|853238_854141_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP014429.1|WP_000070826.1|854842_855472_+|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP014429.1|WP_000654030.1|856231_857245_+|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP014429.1|WP_000279414.1|857297_858308_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP014429.1|WP_001074749.1|858446_859637_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP014429.1|WP_001260089.1|859758_860520_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: NZ_CP014429_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_4

891689-891770

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014429_4

>merge|NZ_CP014429|4|891689-891770|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP014429|4|4|891689-891770|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_001033321.1\|898006_898735_-\|staphylococcal-enterotoxin-type-Q	unknown	unknown	gnl\|CDD\|280949
NZ_CP014429.1\|WP_000290485.1\|890147_890528_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP014429.1\|WP_001190695.1\|889169_889490_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP014429.1\|WP_000932219.1\|890706_891585_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP014429.1\|WP_000734020.1\|897254_897983_-\|staphylococcal-enterotoxin-type-K	unknown	unknown	gnl\|CDD\|280949
NZ_CP014429.1\|WP_001140686.1\|884792_885374_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP014429.1\|WP_000255561.1\|885446_886064_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP014429.1\|WP_000150017.1\|887681_888398_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP014429.1\|WP_000569884.1\|886218_886713_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP014429.1\|WP_000732326.1\|894982_895804_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP014429.1\|WP_000266158.1\|895946_897167_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP014429.1\|WP_000422909.1\|888480_889020_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP014429.1\|WP_001018962.1\|892326_892713_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP014429.1\|WP_000589549.1\|889633_889990_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP014429.1\|WP_000520233.1\|894269_894965_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP014429.1\|WP_000974460.1\|887111_887534_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP014429.1\|WP_001260004.1\|899221_899554_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP014429.1\|WP_000571218.1\|893251_894277_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP014429.1\|WP_001065801.1\|892705_893002_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP014429.1\|WP_000281658.1\|898751_899210_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|368753

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_001033321.1\|898006_898735_-\|staphylococcal-enterotoxin-type-Q	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.46097e-28
NZ_CP014429.1\|WP_000290485.1\|890147_890528_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
NZ_CP014429.1\|WP_001190695.1\|889169_889490_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_CP014429.1\|WP_000932219.1\|890706_891585_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	9.06932e-75
NZ_CP014429.1\|WP_000734020.1\|897254_897983_-\|staphylococcal-enterotoxin-type-K	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.03678e-24
NZ_CP014429.1\|WP_001140686.1\|884792_885374_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.48911e-47
NZ_CP014429.1\|WP_000255561.1\|885446_886064_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	9.12336e-62
NZ_CP014429.1\|WP_000150017.1\|887681_888398_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
NZ_CP014429.1\|WP_000569884.1\|886218_886713_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP014429.1\|WP_000732326.1\|894982_895804_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_CP014429.1\|WP_000266158.1\|895946_897167_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	9.89414e-38
NZ_CP014429.1\|WP_000422909.1\|888480_889020_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.47647e-49
NZ_CP014429.1\|WP_001018962.1\|892326_892713_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP014429.1\|WP_000589549.1\|889633_889990_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP014429.1\|WP_000520233.1\|894269_894965_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_CP014429.1\|WP_000974460.1\|887111_887534_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP014429.1\|WP_001260004.1\|899221_899554_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	6.56309e-09
NZ_CP014429.1\|WP_000571218.1\|893251_894277_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_CP014429.1\|WP_001065801.1\|892705_893002_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP014429.1\|WP_000281658.1\|898751_899210_-\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00223487

>NZ_CP014429.1|WP_000932219.1|890706_891585_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKYFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP014429.1|WP_000290485.1|890147_890528_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NZ_CP014429.1|WP_000589549.1|889633_889990_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP014429.1|WP_001190695.1|889169_889490_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP014429.1|WP_000422909.1|888480_889020_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEGDMPKAPRKNRNLITLY
>NZ_CP014429.1|WP_000150017.1|887681_888398_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>NZ_CP014429.1|WP_000974460.1|887111_887534_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP014429.1|WP_000569884.1|886218_886713_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP014429.1|WP_000255561.1|885446_886064_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>NZ_CP014429.1|WP_001140686.1|884792_885374_+|histidine-phosphatase-family-protein
MAKTLYIMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NZ_CP014429.1|WP_001018962.1|892326_892713_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP014429.1|WP_001065801.1|892705_893002_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP014429.1|WP_000571218.1|893251_894277_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP014429.1|WP_000520233.1|894269_894965_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP014429.1|WP_000732326.1|894982_895804_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP014429.1|WP_000266158.1|895946_897167_-|site-specific-integrase
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEEKLNDKKPTTLKSLTFHVACDEWFQNYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDSKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIESIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
>NZ_CP014429.1|WP_000734020.1|897254_897983_-|staphylococcal-enterotoxin-type-K
MKKLIVIILINIITLSVSNSASAQGDIGIDNLRNFYTKKDFVDLKDVKDNDTPIANQLQFSNVSYDLISESKDFNKFSNFKGKKLDVFGISYNGQCNNKYIYGGVTATNEYLDKPRNIPINIWINGNHKTISTNKVSTNKKFVTAQEIDVKLRKYLQEEYNIYGHNGTKKGEEYGHKSKFYSGFNIGKVTFHLNNNDTFSYDLFYTGDDGLPKSFLKIYEDNKTVESEKFHLDVDISYKETI
>NZ_CP014429.1|WP_001033321.1|898006_898735_-|staphylococcal-enterotoxin-type-Q
MNKIFRVLTVSLFFFTFLIKNNLAYADVGVINLRNFYTNYQPETLQGVSSGNFSTSHQLEYIDGKYTLYSQFHNEYEAKRLKDHKVDIFGISYSGLCNTKYMYGGITLANQNLDKPRNIPINLWVNGKQNTISTDEVSTQKKEVTAQEIDIKLRKYLQNEYNIYGFNKTKKGQEYGYQSKFNSGFNKGKITFHLNNETSFTYDLFYTGTGQAESFLKIYNDNKTIDAENFHLDVEISYEKTE
>NZ_CP014429.1|WP_000281658.1|898751_899210_-|ImmA/IrrE-family-metallo-endopeptidase
MYLYEKMVIENKEIPIDDGKSLGNFEGLYDNGVILINKNLSETRKAEVLYEELAHHKLTYGNILDQSKWINRKFENYARRHGFISAVPLREIVEAYNYGVRNLYELSEYLQLSEKYILEAIEQYKKIYGIGTHYGEYSITFEPLRVFKYKEI
>NZ_CP014429.1|WP_001260004.1|899221_899554_-|helix-turn-helix-transcriptional-regulator
MRTNDEIITIIKTSMKEQNMSLSELARRVGVAKSAVSRYLNLTREFPLNRAEDFAKVLGIKTEYLLGFAEREESTKQDTIAAHLDGDFTEEELIEIRKYAELVRKAHRNQ

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Crispr_ID: NZ_CP014429_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_5

998086-998368

Orphan

Consensus_repeat	Method
AAAGNCAGCTNNNNANANNNTGCAAGTTGG	CRT

4 spacers

The CRISPR arrays of NZ_CP014429_5

>merge|NZ_CP014429|5|998086-998368|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGGCGGGGCCCCAACACAGAGGCTGGCGGAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGAGCCCCGACACAGAGAAATTAGCTCCTCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAAAAAGACAGCAGTAGGATAATTTCAATTTGG

>NZ_CP014429|5|1|998086-998368|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	CGGGGCCCCAACACAGAGGCTGGCGG
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGAGCCCCGACACAGAGAAATTAGC
TCCTCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGCGA
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAA
AAAGACAGCAGTAGGATAATTTCAATTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_000838037.1\|993956_995084_+\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_CP014429.1\|WP_001067294.1\|993217_993595_+\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224023
NZ_CP014429.1\|WP_000154914.1\|1009521_1013175_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP014429.1\|WP_000670752.1\|1013340_1014243_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP014429.1\|WP_000711486.1\|1005309_1005885_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP014429.1\|WP_000167314.1\|995391_996582_+\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
NZ_CP014429.1\|WP_000138486.1\|996690_997935_+\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_CP014429.1\|WP_000758215.1\|1004769_1005294_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP014429.1\|WP_000035058.1\|992208_992802_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|238908
NZ_CP014429.1\|WP_001081626.1\|988804_989233_-\|Na+/H+-antiporter-Mnh1-subunit-B	unknown	unknown	gnl\|CDD\|183602
NZ_CP014429.1\|WP_000172342.1\|1006044_1009521_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP014429.1\|WP_000573079.1\|986974_988471_-\|Na+/H+-antiporter-Mnh1-subunit-D	unknown	unknown	gnl\|CDD\|181085
NZ_CP014429.1\|WP_000066062.1\|999608_1000988_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_CP014429.1\|WP_000054609.1\|989225_991631_-\|Na+/H+-antiporter-Mnh1-subunit-A	unknown	unknown	gnl\|CDD\|237155
NZ_CP014429.1\|WP_000185319.1\|998437_999367_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_CP014429.1\|WP_000781156.1\|991761_992145_-\|kinase-associated-lipoprotein-B	unknown	unknown	gnl\|CDD\|378054
NZ_CP014429.1\|WP_000660045.1\|1000977_1002183_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_CP014429.1\|WP_000007967.1\|1004189_1004765_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP014429.1\|WP_000148855.1\|1002533_1003865_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_CP014429.1\|WP_000402803.1\|988463_988805_-\|Na+/H+-antiporter-Mnh1-subunit-C	unknown	unknown	gnl\|CDD\|181497

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_000838037.1\|993956_995084_+\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_CP014429.1\|WP_001067294.1\|993217_993595_+\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
NZ_CP014429.1\|WP_000154914.1\|1009521_1013175_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP014429.1\|WP_000670752.1\|1013340_1014243_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
NZ_CP014429.1\|WP_000711486.1\|1005309_1005885_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
NZ_CP014429.1\|WP_000167314.1\|995391_996582_+\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_CP014429.1\|WP_000138486.1\|996690_997935_+\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP014429.1\|WP_000758215.1\|1004769_1005294_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
NZ_CP014429.1\|WP_000035058.1\|992208_992802_+\|peptidylprolyl-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
NZ_CP014429.1\|WP_001081626.1\|988804_989233_-\|Na+/H+-antiporter-Mnh1-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
NZ_CP014429.1\|WP_000172342.1\|1006044_1009521_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP014429.1\|WP_000573079.1\|986974_988471_-\|Na+/H+-antiporter-Mnh1-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_CP014429.1\|WP_000066062.1\|999608_1000988_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CP014429.1\|WP_000054609.1\|989225_991631_-\|Na+/H+-antiporter-Mnh1-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_CP014429.1\|WP_000185319.1\|998437_999367_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
NZ_CP014429.1\|WP_000781156.1\|991761_992145_-\|kinase-associated-lipoprotein-B	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	1.89892e-52
NZ_CP014429.1\|WP_000660045.1\|1000977_1002183_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_CP014429.1\|WP_000007967.1\|1004189_1004765_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
NZ_CP014429.1\|WP_000148855.1\|1002533_1003865_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CP014429.1\|WP_000402803.1\|988463_988805_-\|Na+/H+-antiporter-Mnh1-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64

>NZ_CP014429.1|WP_000138486.1|996690_997935_+|Glu/Leu/Phe/Val-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVDEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>NZ_CP014429.1|WP_000167314.1|995391_996582_+|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>NZ_CP014429.1|WP_000838037.1|993956_995084_+|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>NZ_CP014429.1|WP_001067294.1|993217_993595_+|S1-RNA-binding-domain-containing-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>NZ_CP014429.1|WP_000035058.1|992208_992802_+|peptidylprolyl-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>NZ_CP014429.1|WP_000781156.1|991761_992145_-|kinase-associated-lipoprotein-B
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHDRKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>NZ_CP014429.1|WP_000054609.1|989225_991631_-|Na+/H+-antiporter-Mnh1-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>NZ_CP014429.1|WP_001081626.1|988804_989233_-|Na+/H+-antiporter-Mnh1-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>NZ_CP014429.1|WP_000402803.1|988463_988805_-|Na+/H+-antiporter-Mnh1-subunit-C
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>NZ_CP014429.1|WP_000573079.1|986974_988471_-|Na+/H+-antiporter-Mnh1-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVYFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>NZ_CP014429.1|WP_000185319.1|998437_999367_-|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>NZ_CP014429.1|WP_000066062.1|999608_1000988_-|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPSYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>NZ_CP014429.1|WP_000660045.1|1000977_1002183_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>NZ_CP014429.1|WP_000148855.1|1002533_1003865_+|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>NZ_CP014429.1|WP_000007967.1|1004189_1004765_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>NZ_CP014429.1|WP_000758215.1|1004769_1005294_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>NZ_CP014429.1|WP_000711486.1|1005309_1005885_+|signal-peptidase-I
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>NZ_CP014429.1|WP_000172342.1|1006044_1009521_+|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_CP014429.1|WP_000154914.1|1009521_1013175_+|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPKNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_CP014429.1|WP_000670752.1|1013340_1014243_+|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: NZ_CP014429_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_6

1131758-1131845

Orphan

Consensus_repeat	Method
CCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014429_6

>merge|NZ_CP014429|6|1131758-1131845|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGGAAGGAGAGGGATACATGCGCCGAGCACATGCATAAAATCCCCTAACAACTAAAAGTTGTAAGG

>NZ_CP014429|6|5|1131758-1131845|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGG	AAGGAGAGGGATACATGCGCCGAGCACATGCATAAAAT
CCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_000009063.1\|1132140_1133436_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000381849.1\|1138437_1139799_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP014429.1\|WP_000238664.1\|1124888_1125455_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NZ_CP014429.1\|WP_000921968.1\|1129280_1130681_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP014429.1\|WP_000437472.1\|1135782_1136049_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NZ_CP014429.1\|WP_000032727.1\|1120212_1122402_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP014429.1\|WP_001289614.1\|1138006_1138240_-\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|239274
NZ_CP014429.1\|WP_000030812.1\|1123857_1124886_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP014429.1\|WP_000514290.1\|1140947_1141610_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP014429.1\|WP_000709291.1\|1125469_1126948_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP014429.1\|WP_000638456.1\|1139795_1140815_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NZ_CP014429.1\|WP_000685079.1\|1133860_1135033_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP014429.1\|WP_000666799.1\|1119548_1120220_+\|phosphoribosylformylglycinamidine-synthase-I	unknown	unknown	gnl\|CDD\|235140
NZ_CP014429.1\|WP_000033477.1\|1130695_1131271_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NZ_CP014429.1\|WP_000040054.1\|1136051_1137770_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP014429.1\|WP_000273253.1\|1128481_1129288_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP014429.1\|WP_000064214.1\|1131854_1131989_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000483713.1\|1122380_1123865_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NZ_CP014429.1\|WP_000505965.1\|1135086_1135629_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NZ_CP014429.1\|WP_001101908.1\|1126969_1128217_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_000381849.1\|1138437_1139799_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
NZ_CP014429.1\|WP_000238664.1\|1124888_1125455_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	7.23817e-92
NZ_CP014429.1\|WP_000921968.1\|1129280_1130681_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.67975e-64
NZ_CP014429.1\|WP_000437472.1\|1135782_1136049_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
NZ_CP014429.1\|WP_000032727.1\|1120212_1122402_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP014429.1\|WP_001289614.1\|1138006_1138240_-\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	5.00495e-16
NZ_CP014429.1\|WP_000030812.1\|1123857_1124886_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP014429.1\|WP_000514290.1\|1140947_1141610_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
NZ_CP014429.1\|WP_000709291.1\|1125469_1126948_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP014429.1\|WP_000685079.1\|1133860_1135033_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	5.6543e-145
NZ_CP014429.1\|WP_000666799.1\|1119548_1120220_+\|phosphoribosylformylglycinamidine-synthase-I	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.77638e-140
NZ_CP014429.1\|WP_000033477.1\|1130695_1131271_-\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NZ_CP014429.1\|WP_000040054.1\|1136051_1137770_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP014429.1\|WP_000273253.1\|1128481_1129288_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.39205e-29
NZ_CP014429.1\|WP_000638456.1\|1139795_1140815_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	6.42118e-76
NZ_CP014429.1\|WP_000483713.1\|1122380_1123865_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NZ_CP014429.1\|WP_000505965.1\|1135086_1135629_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00779365
NZ_CP014429.1\|WP_001101908.1\|1126969_1128217_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0

>NZ_CP014429.1|WP_000033477.1|1130695_1131271_-|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NZ_CP014429.1|WP_000921968.1|1129280_1130681_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQLPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NZ_CP014429.1|WP_000273253.1|1128481_1129288_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITMAYYCSITLPITGIDDVRLGRVG
>NZ_CP014429.1|WP_001101908.1|1126969_1128217_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYKKVSQIQSDHLFYRHDIANKALQLK
>NZ_CP014429.1|WP_000709291.1|1125469_1126948_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPSGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NZ_CP014429.1|WP_000238664.1|1124888_1125455_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NZ_CP014429.1|WP_000030812.1|1123857_1124886_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>NZ_CP014429.1|WP_000483713.1|1122380_1123865_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NZ_CP014429.1|WP_000032727.1|1120212_1122402_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NZ_CP014429.1|WP_000666799.1|1119548_1120220_+|phosphoribosylformylglycinamidine-synthase-I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>NZ_CP014429.1|WP_000064214.1|1131854_1131989_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NZ_CP014429.1|WP_000009063.1|1132140_1133436_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGDFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NZ_CP014429.1|WP_000685079.1|1133860_1135033_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQQINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSAIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NZ_CP014429.1|WP_000505965.1|1135086_1135629_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISNAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NZ_CP014429.1|WP_000437472.1|1135782_1136049_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NZ_CP014429.1|WP_000040054.1|1136051_1137770_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMGGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NZ_CP014429.1|WP_001289614.1|1138006_1138240_-|glutaredoxin-like-protein-NrdH
MSEIIVYTQNDCPPCTFVKNYLNEHHIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NZ_CP014429.1|WP_000381849.1|1138437_1139799_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NZ_CP014429.1|WP_000638456.1|1139795_1140815_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFGISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>NZ_CP014429.1|WP_000514290.1|1140947_1141610_+|TrkA-family-potassium-uptake-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: NZ_CP014429_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_7

2077067-2077145

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACCTGCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP014429_7

>merge|NZ_CP014429|7|2077067-2077145|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCACATTATCGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCCGCCAACCTGCA

>NZ_CP014429|7|6|2077067-2077145|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCA	CATTATCGTAAGCTGACTTTTCGTCAGCTTCTG
TGTTGGGGCCCCGCCAACCTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_000140176.1\|2083315_2084386_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP014429.1\|WP_001790679.1\|2082386_2082479_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000149064.1\|2074806_2075508_-\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP014429.1\|WP_000037075.1\|2071814_2073032_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP014429.1\|WP_000949467.1\|2081804_2082305_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP014429.1\|WP_001110179.1\|2075522_2075909_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_001795438.1\|2069184_2070441_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP014429.1\|WP_000548781.1\|2084632_2085163_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP014429.1\|WP_000636142.1\|2076125_2076884_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP014429.1\|WP_000228666.1\|2070790_2071255_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP014429.1\|WP_077467091.1\|2073766_2074810_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP014429.1\|WP_000544969.1\|2079466_2080198_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP014429.1\|WP_000180461.1\|2070443_2070644_-\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177
NZ_CP014429.1\|WP_000613733.1\|2082693_2083248_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP014429.1\|WP_000153530.1\|2073147_2073777_-\|two-component-system-response-regulator-VraR	unknown	unknown	gnl\|CDD\|225107
NZ_CP014429.1\|WP_001250336.1\|2080199_2081513_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	unknown	unknown	gnl\|CDD\|223840
NZ_CP014429.1\|WP_001790257.1\|2079270_2079381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_001549145.1\|2078828_2079242_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000999713.1\|2077411_2078398_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP014429.1\|WP_000428172.1\|2071261_2071537_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_000140176.1\|2083315_2084386_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP014429.1\|WP_000149064.1\|2074806_2075508_-\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NZ_CP014429.1\|WP_000037075.1\|2071814_2073032_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
NZ_CP014429.1\|WP_000949467.1\|2081804_2082305_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NZ_CP014429.1\|WP_001795438.1\|2069184_2070441_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP014429.1\|WP_000548781.1\|2084632_2085163_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
NZ_CP014429.1\|WP_000999713.1\|2077411_2078398_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
NZ_CP014429.1\|WP_000228666.1\|2070790_2071255_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP014429.1\|WP_077467091.1\|2073766_2074810_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.20786e-70
NZ_CP014429.1\|WP_000544969.1\|2079466_2080198_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
NZ_CP014429.1\|WP_000180461.1\|2070443_2070644_-\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	2.44511e-24
NZ_CP014429.1\|WP_000153530.1\|2073147_2073777_-\|two-component-system-response-regulator-VraR	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
NZ_CP014429.1\|WP_001250336.1\|2080199_2081513_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	7.18737e-99
NZ_CP014429.1\|WP_000613733.1\|2082693_2083248_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.92778e-75
NZ_CP014429.1\|WP_000636142.1\|2076125_2076884_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126

>NZ_CP014429.1|WP_000636142.1|2076125_2076884_-|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP014429.1|WP_001110179.1|2075522_2075909_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP014429.1|WP_000149064.1|2074806_2075508_-|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP014429.1|WP_077467091.1|2073766_2074810_-|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMCERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP014429.1|WP_000153530.1|2073147_2073777_-|two-component-system-response-regulator-VraR
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP014429.1|WP_000037075.1|2071814_2073032_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP014429.1|WP_000428172.1|2071261_2071537_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP014429.1|WP_000228666.1|2070790_2071255_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP014429.1|WP_000180461.1|2070443_2070644_-|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
>NZ_CP014429.1|WP_001795438.1|2069184_2070441_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAGKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>NZ_CP014429.1|WP_000999713.1|2077411_2078398_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP014429.1|WP_001549145.1|2078828_2079242_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDCDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>NZ_CP014429.1|WP_001790257.1|2079270_2079381_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP014429.1|WP_000544969.1|2079466_2080198_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>NZ_CP014429.1|WP_001250336.1|2080199_2081513_-|lipid-II-isoglutaminyl-synthase-subunit-MurT
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP014429.1|WP_000949467.1|2081804_2082305_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP014429.1|WP_001790679.1|2082386_2082479_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP014429.1|WP_000613733.1|2082693_2083248_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP014429.1|WP_000140176.1|2083315_2084386_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP014429.1|WP_000548781.1|2084632_2085163_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

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Crispr_ID: NZ_CP014429_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_8

2312131-2312281

Orphan

Consensus_repeat	Method
AACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NZ_CP014429_8

>merge|NZ_CP014429|8|2312131-2312281|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCTTTCTA

>NZ_CP014429|8|7|2312131-2312281|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTTA
AACTTTAGTTGTTAGGGGCTCTTATGCA	GTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTC
AACTTTAGTTGTTAGGGGCTTCTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_001024094.1\|2308636_2309302_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP014429.1\|WP_000003759.1\|2309453_2309774_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP014429.1\|WP_000083807.1\|2320050_2321589_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP014429.1\|WP_000808817.1\|2307002_2307233_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000908176.1\|2316550_2317333_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP014429.1\|WP_000019744.1\|2309775_2310756_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP014429.1\|WP_000927360.1\|2321623_2323756_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP014429.1\|WP_000495671.1\|2311021_2312113_+\|lytic-regulatory-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000123393.1\|2304957_2306331_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP014429.1\|WP_000070866.1\|2303443_2303887_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP014429.1\|WP_001802298.1\|2312612_2312717_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_001123303.1\|2304086_2304500_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP014429.1\|WP_000115564.1\|2313403_2314540_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_CP014429.1\|WP_000334465.1\|2317564_2319370_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP014429.1\|WP_001127960.1\|2307263_2308202_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP014429.1\|WP_001292149.1\|2323767_2324202_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP014429.1\|WP_000160304.1\|2302612_2303323_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP014429.1\|WP_000648718.1\|2324201_2325308_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP014429.1\|WP_000370924.1\|2315625_2316483_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP014429.1\|WP_001790138.1\|2314828_2314921_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_001024094.1\|2308636_2309302_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
NZ_CP014429.1\|WP_000003759.1\|2309453_2309774_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP014429.1\|WP_000083807.1\|2320050_2321589_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP014429.1\|WP_001127960.1\|2307263_2308202_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP014429.1\|WP_000908176.1\|2316550_2317333_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	4.88024e-103
NZ_CP014429.1\|WP_000019744.1\|2309775_2310756_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
NZ_CP014429.1\|WP_000927360.1\|2321623_2323756_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.74009e-67
NZ_CP014429.1\|WP_000123393.1\|2304957_2306331_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP014429.1\|WP_000070866.1\|2303443_2303887_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP014429.1\|WP_001123303.1\|2304086_2304500_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP014429.1\|WP_000115564.1\|2313403_2314540_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.91533e-06
NZ_CP014429.1\|WP_000334465.1\|2317564_2319370_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP014429.1\|WP_000648718.1\|2324201_2325308_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP014429.1\|WP_001292149.1\|2323767_2324202_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP014429.1\|WP_000160304.1\|2302612_2303323_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP014429.1\|WP_000370924.1\|2315625_2316483_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59

>NZ_CP014429.1|WP_000495671.1|2311021_2312113_+|lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP014429.1|WP_000019744.1|2309775_2310756_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP014429.1|WP_000003759.1|2309453_2309774_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP014429.1|WP_001024094.1|2308636_2309302_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>NZ_CP014429.1|WP_001127960.1|2307263_2308202_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP014429.1|WP_000808817.1|2307002_2307233_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP014429.1|WP_000123393.1|2304957_2306331_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP014429.1|WP_001123303.1|2304086_2304500_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP014429.1|WP_000070866.1|2303443_2303887_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP014429.1|WP_000160304.1|2302612_2303323_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP014429.1|WP_001802298.1|2312612_2312717_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP014429.1|WP_000115564.1|2313403_2314540_-|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>NZ_CP014429.1|WP_001790138.1|2314828_2314921_+|hypothetical-protein
MFIFKTTSKSHFHNNVKSLECIKIPINKNR
>NZ_CP014429.1|WP_000370924.1|2315625_2316483_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>NZ_CP014429.1|WP_000908176.1|2316550_2317333_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMFAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP014429.1|WP_000334465.1|2317564_2319370_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP014429.1|WP_000083807.1|2320050_2321589_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP014429.1|WP_000927360.1|2321623_2323756_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLDQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP014429.1|WP_001292149.1|2323767_2324202_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP014429.1|WP_000648718.1|2324201_2325308_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

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Crispr_ID: NZ_CP014429_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014429_9

2436049-2436242

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of NZ_CP014429_9

>merge|NZ_CP014429|9|2436049-2436242|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>NZ_CP014429|9|2|2436049-2436242|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014429.1\|WP_000913019.1\|2442741_2443347_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP014429.1\|WP_000259718.1\|2439212_2440472_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP014429.1\|WP_000230173.1\|2436383_2437406_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP014429.1\|WP_001790034.1\|2435818_2435989_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000808500.1\|2438270_2438717_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP014429.1\|WP_001549681.1\|2432427_2432679_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000413865.1\|2430773_2432039_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP014429.1\|WP_000184419.1\|2434029_2435241_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP014429.1\|WP_000066900.1\|2435342_2435693_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP014429.1\|WP_001161085.1\|2426985_2427303_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000866971.1\|2438031_2438265_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP014429.1\|WP_000600967.1\|2432670_2433435_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP014429.1\|WP_000503817.1\|2441030_2441537_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP014429.1\|WP_000051206.1\|2426576_2426741_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014429.1\|WP_000643988.1\|2437425_2438025_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP014429.1\|WP_000602937.1\|2438730_2439216_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP014429.1\|WP_000951059.1\|2433596_2434037_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP014429.1\|WP_000592303.1\|2427489_2430657_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP014429.1\|WP_000076929.1\|2441567_2442572_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NZ_CP014429.1\|WP_000134528.1\|2440534_2441029_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483

Protein	Function_ID	Function_description	E-value
NZ_CP014429.1\|WP_000913019.1\|2442741_2443347_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NZ_CP014429.1\|WP_000259718.1\|2439212_2440472_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
NZ_CP014429.1\|WP_000230173.1\|2436383_2437406_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP014429.1\|WP_000808500.1\|2438270_2438717_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP014429.1\|WP_000076929.1\|2441567_2442572_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
NZ_CP014429.1\|WP_000413865.1\|2430773_2432039_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
NZ_CP014429.1\|WP_000184419.1\|2434029_2435241_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
NZ_CP014429.1\|WP_000066900.1\|2435342_2435693_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP014429.1\|WP_000866971.1\|2438031_2438265_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP014429.1\|WP_000600967.1\|2432670_2433435_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_CP014429.1\|WP_000503817.1\|2441030_2441537_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.02752e-64
NZ_CP014429.1\|WP_000643988.1\|2437425_2438025_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP014429.1\|WP_000602937.1\|2438730_2439216_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NZ_CP014429.1\|WP_000951059.1\|2433596_2434037_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.873e-15
NZ_CP014429.1\|WP_000592303.1\|2427489_2430657_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP014429.1\|WP_000134528.1\|2440534_2441029_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98

>NZ_CP014429.1|WP_001790034.1|2435818_2435989_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_CP014429.1|WP_000066900.1|2435342_2435693_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP014429.1|WP_000184419.1|2434029_2435241_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP014429.1|WP_000951059.1|2433596_2434037_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLREAHND
>NZ_CP014429.1|WP_000600967.1|2432670_2433435_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP014429.1|WP_001549681.1|2432427_2432679_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_CP014429.1|WP_000413865.1|2430773_2432039_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP014429.1|WP_000592303.1|2427489_2430657_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP014429.1|WP_001161085.1|2426985_2427303_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP014429.1|WP_000051206.1|2426576_2426741_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP014429.1|WP_000230173.1|2436383_2437406_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP014429.1|WP_000643988.1|2437425_2438025_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP014429.1|WP_000866971.1|2438031_2438265_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP014429.1|WP_000808500.1|2438270_2438717_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP014429.1|WP_000602937.1|2438730_2439216_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP014429.1|WP_000259718.1|2439212_2440472_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP014429.1|WP_000134528.1|2440534_2441029_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_CP014429.1|WP_000503817.1|2441030_2441537_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIDGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP014429.1|WP_000076929.1|2441567_2442572_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP014429.1|WP_000913019.1|2442741_2443347_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP014429_4	4.1\|891713\|34\|NZ_CP014429\|CRISPRCasFinder	891713-891746	34	NZ_CP014429.1	1424259-1424292	0	1.0
NZ_CP014429_4	4.1\|891713\|34\|NZ_CP014429\|CRISPRCasFinder	891713-891746	34	NZ_CP014429.1	1513451-1513484	0	1.0
NZ_CP014429_9	9.2\|2436128\|36\|NZ_CP014429\|CRT	2436128-2436163	36	NZ_CP014429.1	1216033-1216068	0	1.0
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP014429.1	811327-811352	1	0.962
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP014429.1	2877294-2877319	1	0.962
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP014429.1	2877350-2877375	1	0.962
NZ_CP014429_5	5.1\|998116\|26\|NZ_CP014429\|CRT	998116-998141	26	NZ_CP014429.1	998060-998085	1	0.962
NZ_CP014429_5	5.3\|998230\|26\|NZ_CP014429\|CRT	998230-998255	26	NZ_CP014429.1	848446-848471	1	0.962
NZ_CP014429_7	7.1\|2077090\|33\|NZ_CP014429\|CRISPRCasFinder	2077090-2077122	33	NZ_CP014429.1	848426-848458	1	0.97
NZ_CP014429_7	7.1\|2077090\|33\|NZ_CP014429\|CRISPRCasFinder	2077090-2077122	33	NZ_CP014429.1	1216089-1216121	1	0.97
NZ_CP014429_7	7.1\|2077090\|33\|NZ_CP014429\|CRISPRCasFinder	2077090-2077122	33	NZ_CP014429.1	1424214-1424246	1	0.97
NZ_CP014429_7	7.1\|2077090\|33\|NZ_CP014429\|CRISPRCasFinder	2077090-2077122	33	NZ_CP014429.1	1742015-1742047	1	0.97
NZ_CP014429_7	7.1\|2077090\|33\|NZ_CP014429\|CRISPRCasFinder	2077090-2077122	33	NZ_CP014429.1	2712009-2712041	1	0.97
NZ_CP014429_9	9.2\|2436128\|36\|NZ_CP014429\|CRT	2436128-2436163	36	NZ_CP014429.1	1920467-1920502	1	0.972
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP014429.1	811383-811408	2	0.923
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP014429.1	998060-998085	2	0.923
NZ_CP014429_5	5.1\|998116\|26\|NZ_CP014429\|CRT	998116-998141	26	NZ_CP014429.1	811327-811352	2	0.923
NZ_CP014429_5	5.1\|998116\|26\|NZ_CP014429\|CRT	998116-998141	26	NZ_CP014429.1	2877294-2877319	2	0.923
NZ_CP014429_5	5.1\|998116\|26\|NZ_CP014429\|CRT	998116-998141	26	NZ_CP014429.1	2877350-2877375	2	0.923
NZ_CP014429_5	5.3\|998230\|26\|NZ_CP014429\|CRT	998230-998255	26	NZ_CP014429.1	394724-394749	2	0.923
NZ_CP014429_7	7.1\|2077090\|33\|NZ_CP014429\|CRISPRCasFinder	2077090-2077122	33	NZ_CP014429.1	1513497-1513529	2	0.939
NZ_CP014429_9	9.1\|2436072\|33\|NZ_CP014429\|CRT	2436072-2436104	33	NZ_CP014429.1	848426-848458	2	0.939
NZ_CP014429_9	9.1\|2436072\|33\|NZ_CP014429\|CRT	2436072-2436104	33	NZ_CP014429.1	1216089-1216121	2	0.939
NZ_CP014429_9	9.1\|2436072\|33\|NZ_CP014429\|CRT	2436072-2436104	33	NZ_CP014429.1	1424214-1424246	2	0.939
NZ_CP014429_9	9.1\|2436072\|33\|NZ_CP014429\|CRT	2436072-2436104	33	NZ_CP014429.1	1513497-1513529	2	0.939
NZ_CP014429_9	9.1\|2436072\|33\|NZ_CP014429\|CRT	2436072-2436104	33	NZ_CP014429.1	2712009-2712041	2	0.939
NZ_CP014429_9	9.2\|2436128\|36\|NZ_CP014429\|CRT	2436128-2436163	36	NZ_CP014429.1	1741954-1741989	2	0.944
NZ_CP014429_9	9.2\|2436128\|36\|NZ_CP014429\|CRT	2436128-2436163	36	NZ_CP014429.1	2087834-2087869	2	0.944
NZ_CP014429_9	9.3\|2436187\|33\|NZ_CP014429\|CRT	2436187-2436219	33	NZ_CP014429.1	848426-848458	2	0.939
NZ_CP014429_9	9.3\|2436187\|33\|NZ_CP014429\|CRT	2436187-2436219	33	NZ_CP014429.1	1216089-1216121	2	0.939
NZ_CP014429_9	9.3\|2436187\|33\|NZ_CP014429\|CRT	2436187-2436219	33	NZ_CP014429.1	1424214-1424246	2	0.939
NZ_CP014429_9	9.3\|2436187\|33\|NZ_CP014429\|CRT	2436187-2436219	33	NZ_CP014429.1	2712009-2712041	2	0.939

1. spacer 4.1|891713|34|NZ_CP014429|CRISPRCasFinder matches to position: 1424259-1424292, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

2. spacer 4.1|891713|34|NZ_CP014429|CRISPRCasFinder matches to position: 1513451-1513484, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 9.2|2436128|36|NZ_CP014429|CRT matches to position: 1216033-1216068, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttctttttgaaattctcta	Protospacer
************************************

4. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to position: 811327-811352, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** ********************

5. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to position: 2877294-2877319, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
************.*************

6. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to position: 2877350-2877375, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctttgttggggccccg	Protospacer
************ *************

7. spacer 5.1|998116|26|NZ_CP014429|CRT matches to position: 998060-998085, mismatch: 1, identity: 0.962

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaggctggtgg	Protospacer
***********************.**

8. spacer 5.3|998230|26|NZ_CP014429|CRT matches to position: 848446-848471, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

9. spacer 7.1|2077090|33|NZ_CP014429|CRISPRCasFinder matches to position: 848426-848458, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

10. spacer 7.1|2077090|33|NZ_CP014429|CRISPRCasFinder matches to position: 1216089-1216121, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

11. spacer 7.1|2077090|33|NZ_CP014429|CRISPRCasFinder matches to position: 1424214-1424246, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

12. spacer 7.1|2077090|33|NZ_CP014429|CRISPRCasFinder matches to position: 1742015-1742047, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattatagtaagctgacttttcgtcagcttctg	Protospacer
****** **************************

13. spacer 7.1|2077090|33|NZ_CP014429|CRISPRCasFinder matches to position: 2712009-2712041, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

14. spacer 9.2|2436128|36|NZ_CP014429|CRT matches to position: 1920467-1920502, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

15. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to position: 811383-811408, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
***** ******.*************

16. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to position: 998060-998085, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccaccagcctctgtgttggggccccg	Protospacer
**.*****.*****************

17. spacer 5.1|998116|26|NZ_CP014429|CRT matches to position: 811327-811352, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*****************.** *****

18. spacer 5.1|998116|26|NZ_CP014429|CRT matches to position: 2877294-2877319, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

19. spacer 5.1|998116|26|NZ_CP014429|CRT matches to position: 2877350-2877375, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacaaagaagctggcgg	Protospacer
************* ***.********

20. spacer 5.3|998230|26|NZ_CP014429|CRT matches to position: 394724-394749, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacaaagaagctgacga	Protospacer
************* ********.***

21. spacer 7.1|2077090|33|NZ_CP014429|CRISPRCasFinder matches to position: 1513497-1513529, mismatch: 2, identity: 0.939

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
******.******************* ******

22. spacer 9.1|2436072|33|NZ_CP014429|CRT matches to position: 848426-848458, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

23. spacer 9.1|2436072|33|NZ_CP014429|CRT matches to position: 1216089-1216121, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

24. spacer 9.1|2436072|33|NZ_CP014429|CRT matches to position: 1424214-1424246, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

25. spacer 9.1|2436072|33|NZ_CP014429|CRT matches to position: 1513497-1513529, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

26. spacer 9.1|2436072|33|NZ_CP014429|CRT matches to position: 2712009-2712041, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

27. spacer 9.2|2436128|36|NZ_CP014429|CRT matches to position: 1741954-1741989, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

28. spacer 9.2|2436128|36|NZ_CP014429|CRT matches to position: 2087834-2087869, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

29. spacer 9.3|2436187|33|NZ_CP014429|CRT matches to position: 848426-848458, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

30. spacer 9.3|2436187|33|NZ_CP014429|CRT matches to position: 1216089-1216121, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

31. spacer 9.3|2436187|33|NZ_CP014429|CRT matches to position: 1424214-1424246, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

32. spacer 9.3|2436187|33|NZ_CP014429|CRT matches to position: 2712009-2712041, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014429_5	5.4\|998286\|53\|NZ_CP014429\|CRT	998286-998338	53	MG543995	Staphylococcus phage UPMK_1, partial genome	76246-76298	4	0.925
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP034332	Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence	3359-3384	5	0.808
NZ_CP014429_3	3.1\|848390\|26\|NZ_CP014429\|CRISPRCasFinder	848390-848415	26	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	715511-715536	5	0.808
NZ_CP014429_5	5.3\|998230\|26\|NZ_CP014429\|CRT	998230-998255	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NZ_CP014429_7	7.1\|2077090\|33\|NZ_CP014429\|CRISPRCasFinder	2077090-2077122	33	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159745-159777	10	0.697

1. spacer 5.4|998286|53|NZ_CP014429|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.925

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttgagaaactatcatttctgtcccactccctt	Protospacer
************************ **** *********************

2. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

3. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to NZ_CP034332 (Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtctgggcctac	Protospacer
****************. *****.

4. spacer 3.1|848390|26|NZ_CP014429|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtttggccctga	Protospacer
***************** ** **. .

5. spacer 5.3|998230|26|NZ_CP014429|CRT matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcga	CRISPR spacer
taaggcctcaacacagaagctggcgt	Protospacer
...****.*****************

6. spacer 7.1|2077090|33|NZ_CP014429|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 10, identity: 0.697

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
ttttatcgtaaggtgagttttcgtcaagcacct	Protospacer
. ********** *** *********. . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

780018 : 787838

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244412.1\|780018_781074_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
WP_000149344.1\|781073_781760_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|781734_782208_-	DoxX family protein	NA	NA	NA	NA
WP_001093553.1\|782549_782990_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637687.1\|783269_783854_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|783952_784666_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|784669_785089_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|785090_785759_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604514.1\|786109_786703_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217785.1\|786686_787838_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_2

799810 : 814541

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|799810_800869_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197273.1\|801219_801762_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429014.1\|802385_803303_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
WP_001790641.1\|803393_803495_+	hypothetical protein	NA	NA	NA	NA
WP_000193752.1\|803572_805078_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|805418_805919_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|805938_806805_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|807605_808004_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|807966_810072_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|810189_811161_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|811674_811830_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|811868_812840_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|812826_813783_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616842.1\|813779_814541_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_3

893251 : 960237

Staphylococcus_phage(63.86%)

plate,portal,head,capsid,tail,terminase,integrase,holin

attL 901054:901073|attR 957016:957035

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571218.1\|893251_894277_+	methionine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.9e-26	33.3
WP_000520233.1\|894269_894965_+	ABC transporter permease	NA	NA	NA	NA
WP_000732326.1\|894982_895804_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000266158.1\|895946_897167_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	2.9e-100	47.5
WP_000734020.1\|897254_897983_-	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	1.2e-21	31.8
WP_001033321.1\|898006_898735_-	staphylococcal enterotoxin type Q	A0EX09	Staphylococcus_phage	1.6e-26	34.1
WP_000281658.1\|898751_899210_-	ImmA/IrrE family metallo-endopeptidase	A0A2I6PEK4	Staphylococcus_phage	4.3e-65	82.1
WP_001260004.1\|899221_899554_-	helix-turn-helix transcriptional regulator	A0A1J0MFC1	Staphylococcus_phage	1.6e-37	74.5
WP_000243849.1\|899746_900010_+	helix-turn-helix transcriptional regulator	A0A2H4J9X2	uncultured_Caudovirales_phage	4.1e-36	94.8
WP_000091732.1\|900002_900275_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	4.8e-40	88.9
WP_000784892.1\|900286_900460_+	hypothetical protein	NA	NA	NA	NA
WP_001231376.1\|900426_900630_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	2.0e-30	98.5
WP_000403840.1\|900631_901015_+	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	4.4e-63	96.9
WP_001103959.1\|901015_901264_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.4e-22	58.6
901054:901073	attL	NA	NA	NA	NA
WP_000985235.1\|901355_903728_+	primase	A0A2H4JCU9	uncultured_Caudovirales_phage	9.8e-137	39.3
WP_001081424.1\|904398_904743_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	9.4e-41	65.2
WP_000884055.1\|904967_905174_+	hypothetical protein	NA	NA	NA	NA
WP_000657538.1\|905160_906219_+\|capsid	phage capsid protein	A0A0K2CZ99	Paenibacillus_phage	3.6e-14	26.6
WP_000253084.1\|906402_906894_+	hypothetical protein	A0A2H4JB26	uncultured_Caudovirales_phage	7.9e-25	40.5
WP_000801979.1\|907322_908291_+	Abi family protein	A0A0H4U080	Erysipelothrix_phage	5.9e-24	27.3
WP_001035618.1\|908525_909080_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	4.8e-71	76.1
WP_000752917.1\|910113_910308_+	CsbD family protein	NA	NA	NA	NA
WP_001183858.1\|910540_911392_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_000168845.1\|911719_912481_+	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3
WP_000205572.1\|912578_913886_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_001006454.1\|913991_915242_+	cysteine desulfurase	Q2XUY6	environmental_halophage	1.4e-110	44.5
WP_001010508.1\|915231_915696_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_001074405.1\|915846_917244_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_050961182.1\|917311_918361_-\|integrase	site-specific integrase	A1KWY3	Staphylococcus_virus	7.7e-203	99.7
WP_050961183.1\|918422_918938_-	hypothetical protein	I1W624	Staphylococcus_phage	1.5e-37	99.4
WP_000896616.1\|918941_919442_-	hypothetical protein	B7T094	Staphylococcus_virus	1.1e-71	100.0
WP_050961185.1\|919489_920164_-	LexA family transcriptional regulator	A0A1W6JPS3	Staphylococcus_phage	6.6e-115	91.1
WP_001014907.1\|920355_920595_+	helix-turn-helix transcriptional regulator	A0A2H4J3I3	uncultured_Caudovirales_phage	1.2e-31	88.5
WP_050961186.1\|920610_920814_+	hypothetical protein	A0A0E3XBM9	Staphylococcus_phage	6.1e-32	98.5
WP_050961187.1\|921001_921793_+	phage antirepressor KilAC domain-containing protein	Q8SDX0	Staphylococcus_phage	7.2e-145	99.2
WP_000187184.1\|921793_922018_+	hypothetical protein	A0A0F6N4M2	Staphylococcus_phage	3.2e-34	100.0
WP_025920885.1\|922057_922507_+	hypothetical protein	A1KWZ2	Staphylococcus_virus	6.7e-79	99.3
WP_000977378.1\|922520_922742_+	hypothetical protein	E0Y3P2	Staphylococcus_virus	1.5e-31	100.0
WP_000066013.1\|922734_922902_+	DUF1270 domain-containing protein	S4V7J2	Staphylococcus_phage	4.0e-21	96.4
WP_033843163.1\|922902_923223_+	hypothetical protein	S4V968	Staphylococcus_phage	2.4e-54	99.1
WP_000291075.1\|923316_923577_+	DUF1108 family protein	A0A059T5A3	Staphylococcus_phage	1.2e-43	100.0
WP_000802315.1\|923584_923821_+	hypothetical protein	D2JGJ9	Staphylococcus_phage	2.7e-39	100.0
WP_000002513.1\|923813_924293_+	siphovirus Gp157 family protein	D2JGK0	Staphylococcus_phage	5.3e-82	100.0
WP_001288247.1\|924292_925066_+	AAA family ATPase	A0EWP9	Staphylococcus_virus	1.6e-141	100.0
WP_050961188.1\|925096_925651_+	single-stranded DNA-binding protein	A7TWM8	Staphylococcus_phage	2.2e-100	99.5
WP_050961189.1\|925663_926329_+	hypothetical protein	Q4ZDY3	Staphylococcus_virus	7.7e-124	98.2
WP_050961190.1\|926328_927111_+	AP2 domain-containing protein	A0A2I6PDA5	Staphylococcus_phage	4.1e-140	99.2
WP_050961191.1\|927082_927898_+	phage replisome organizer N-terminal domain-containing protein	Q4ZAS2	Staphylococcus_virus	8.9e-114	96.7
WP_050961192.1\|927907_928687_+	ATP-binding protein	Q6R838	Staphylococcus_virus	5.1e-143	98.8
WP_000237153.1\|928680_928842_+	hypothetical protein	D2JGK6	Staphylococcus_phage	4.5e-22	100.0
WP_001123688.1\|928854_929076_+	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_031898212.1\|929085_929493_+	RusA family crossover junction endodeoxyribonuclease	D2JGK8	Staphylococcus_phage	5.5e-72	97.8
WP_031898213.1\|929492_929678_+	DUF3113 family protein	A0A0H3U473	Staphylococcus_phage	6.0e-26	96.7
WP_050961193.1\|929678_930296_+	hypothetical protein	A0A059T7P3	Staphylococcus_phage	2.8e-83	99.0
WP_050961194.1\|930296_930545_+	hypothetical protein	S4V683	Staphylococcus_phage	1.6e-42	98.8
WP_000693615.1\|930558_930945_+	hypothetical protein	I1W655	Staphylococcus_phage	4.1e-69	100.0
WP_050961195.1\|931132_931558_+	hypothetical protein	A0A2I6PE09	Staphylococcus_phage	4.8e-79	100.0
WP_050961196.1\|931571_932081_+	hypothetical protein	A0A1X9H0D4	Staphylococcus_phage	2.5e-82	88.8
WP_001065056.1\|932400_932649_+	DUF1024 family protein	Q4ZCN8	Staphylococcus_virus	2.4e-38	100.0
WP_000185662.1\|932641_933172_+	dUTP diphosphatase	B2ZYX2	Staphylococcus_phage	1.9e-96	100.0
WP_031764620.1\|933208_933415_+	DUF1381 domain-containing protein	B7T0C2	Staphylococcus_virus	9.3e-20	97.1
WP_031924097.1\|933411_933585_+	transcriptional regulator	Q4ZBK0	Staphylococcus_phage	1.9e-21	98.2
WP_000990005.1\|933585_933732_+	hypothetical protein	B2ZYX7	Staphylococcus_phage	2.2e-15	100.0
WP_000058632.1\|933746_934166_+	transcriptional regulator	I1W651	Staphylococcus_phage	8.1e-71	100.0
WP_001003271.1\|934352_934793_+\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	4.8e-74	100.0
WP_000169945.1\|934779_936057_+\|terminase	PBSX family phage terminase large subunit	S4V685	Staphylococcus_phage	1.3e-249	100.0
WP_000921887.1\|936067_937603_+\|portal	phage portal protein	A1KX25	Staphylococcus_virus	5.8e-292	100.0
WP_001813737.1\|937609_938605_+\|capsid	minor capsid protein	E0Y3K7	Staphylococcus_virus	3.8e-183	99.4
WP_031898218.1\|938677_938827_+	hypothetical protein	Q4ZDN0	Staphylococcus_virus	3.7e-10	64.3
WP_031925652.1\|938935_939556_+	DUF4355 domain-containing protein	B2ZYY4	Staphylococcus_phage	1.2e-67	92.2
WP_000438500.1\|939569_940544_+\|capsid	phage major capsid protein	B7T0D2	Staphylococcus_virus	1.8e-182	99.7
WP_001114085.1\|940565_940853_+	hypothetical protein	S4V6D9	Staphylococcus_phage	4.7e-46	100.0
WP_000208959.1\|940861_941194_+\|head,tail	phage head-tail connector protein	E0Y3L2	Staphylococcus_virus	7.1e-54	100.0
WP_031880723.1\|941190_941493_+	hypothetical protein	E0Y3L3	Staphylococcus_virus	7.4e-50	99.0
WP_001017815.1\|941492_941840_+	HK97 gp10 family phage protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
WP_000188640.1\|941851_942235_+	hypothetical protein	E0Y3L5	Staphylococcus_virus	1.0e-67	98.4
WP_031898198.1\|942253_942835_+\|tail	phage major tail protein, TP901-1 family	Q8SDU0	Staphylococcus_phage	3.5e-104	97.9
WP_031898197.1\|942896_943262_+\|tail	tail assembly protein	A0A0F6N4J9	Staphylococcus_phage	6.2e-59	99.2
WP_001599101.1\|943291_943636_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	7.2e-57	99.1
WP_050961197.1\|943652_947120_+	hypothetical protein	A0EWM3	Staphylococcus_virus	1.7e-246	99.3
WP_031898192.1\|947132_948080_+\|tail	phage tail family protein	Q8SDT6	Staphylococcus_phage	8.0e-183	99.7
WP_000156414.1\|948088_949990_+\|tail	phage tail protein	Q8SDT5	Staphylococcus_phage	0.0e+00	97.9
WP_050961198.1\|950004_951915_+	hypothetical protein	B2ZYZ7	Staphylococcus_phage	0.0e+00	99.2
WP_077467085.1\|951914_953738_+\|plate	phage baseplate upper protein	B1H3M3	Staphylococcus_phage	0.0e+00	99.5
WP_031844790.1\|953737_954115_+	DUF2977 domain-containing protein	A0A0F6N3G4	Staphylococcus_phage	7.6e-60	99.2
WP_000782200.1\|954118_954292_+	XkdX family protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
WP_000466777.1\|954331_954631_+	DUF2951 domain-containing protein	A0A0F6N3M6	Staphylococcus_phage	9.9e-47	100.0
WP_050961200.1\|954767_956666_+	glucosaminidase domain-containing protein	A1KX46	Staphylococcus_virus	0.0e+00	98.9
WP_031890881.1\|956678_957917_+\|plate	BppU family phage baseplate upper protein	A0A0F6N3G7	Staphylococcus_phage	3.3e-205	96.6
957016:957035	attR	NA	NA	NA	NA
WP_031890882.1\|957922_958318_+	hypothetical protein	A0A0E3XBL9	Staphylococcus_phage	6.1e-68	99.2
WP_000354119.1\|958373_958811_+\|holin	phage holin	A0EWV0	Staphylococcus_virus	1.1e-73	100.0
WP_050961201.1\|958791_960237_+	SH3 domain-containing protein	Q4ZB16	Staphylococcus_virus	7.2e-292	98.3

DBSCAN-SWA_4

1116982 : 1125455

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1116982_1117465_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010412.1\|1117451_1118576_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1118579_1119284_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1119283_1119547_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1119548_1120220_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032727.1\|1120212_1122402_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483713.1\|1122380_1123865_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030812.1\|1123857_1124886_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238664.1\|1124888_1125455_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_5

1567223 : 1652759

106

Staphylococcus_phage(84.21%)

tRNA,terminase,protease,plate,portal,head,capsid,tail,holin,integrase

attL 1603586:1603606|attR 1652764:1652784

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858789.1\|1567223_1568516_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0
WP_000525078.1\|1568837_1571531_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000049919.1\|1571554_1572526_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361544.1\|1572512_1573715_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	3.2e-35	42.5
WP_000690027.1\|1573719_1574862_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839926.1\|1575102_1575420_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_001827022.1\|1575756_1576437_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000152734.1\|1576508_1577096_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000004947.1\|1577085_1577661_-	YpiB family protein	G3MAV7	Bacillus_virus	2.7e-08	27.2
WP_000389524.1\|1577674_1578919_-	hypothetical protein	NA	NA	NA	NA
WP_000245895.1\|1578925_1580224_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776323.1\|1580233_1581298_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269929.1\|1581323_1582490_-	chorismate synthase	A0A291AU41	Pandoravirus	7.6e-34	32.1
WP_000789522.1\|1582875_1583076_-	hypothetical protein	NA	NA	NA	NA
WP_000442480.1\|1583284_1583734_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_001096471.1\|1583825_1584785_-	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_077467087.1\|1584786_1585512_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450553.1\|1585514_1586087_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1586517_1586790_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161738.1\|1586960_1587959_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165536.1\|1587975_1589286_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000133954.1\|1589507_1590683_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_001789944.1\|1590939_1591131_-	hypothetical protein	NA	NA	NA	NA
WP_001789945.1\|1591247_1591364_-	hypothetical protein	NA	NA	NA	NA
WP_000644391.1\|1591394_1592054_-	(d)CMP kinase	NA	NA	NA	NA
WP_000681756.1\|1592130_1593099_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1593213_1594200_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_001789943.1\|1594360_1594477_-	hypothetical protein	NA	NA	NA	NA
WP_000069282.1\|1594601_1596062_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902119.1\|1596214_1597594_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
WP_001163801.1\|1597583_1598537_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001151997.1\|1598644_1598893_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186912.1\|1598998_1599544_-	ECF transporter S component	NA	NA	NA	NA
WP_001789947.1\|1599822_1599942_-	hypothetical protein	NA	NA	NA	NA
WP_000913219.1\|1600140_1601055_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001033757.1\|1601069_1601276_-	hypothetical protein	NA	NA	NA	NA
WP_000472936.1\|1601268_1602207_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476873.1\|1602263_1603181_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000470336.1\|1603271_1603457_-	hypothetical protein	A0ZS61	Staphylococcus_virus	1.7e-25	100.0
1603586:1603606	attL	NA	NA	NA	NA
WP_024937002.1\|1603705_1604689_-	Panton-Valentine bi-component leukocidin subunit F	A0A2I6PEU3	Staphylococcus_phage	4.0e-185	100.0
WP_000239545.1\|1604684_1605623_-	Panton-Valentine bi-component leukocidin subunit S	A0A2I6PER8	Staphylococcus_phage	3.7e-180	100.0
WP_000909220.1\|1606012_1607467_-	N-acetylmuramoyl-L-alanine amidase	A0A2I6PET7	Staphylococcus_phage	5.7e-289	100.0
WP_000339146.1\|1607477_1607780_-\|holin	phage holin	A0A2I6PET6	Staphylococcus_phage	7.0e-48	100.0
WP_000466784.1\|1607915_1608215_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_000868795.1\|1608534_1609032_+	trimethoprim-resistant dihydrofolate reductase DfrG	G3MBI7	Bacillus_virus	4.0e-40	49.1
WP_000163792.1\|1609103_1611056_-	hypothetical protein	NA	NA	NA	NA
WP_001159903.1\|1611062_1611299_-	hypothetical protein	NA	NA	NA	NA
WP_000916020.1\|1611545_1611710_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|1611702_1612092_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_000067127.1\|1612091_1613558_-\|plate	phage baseplate upper protein	A0A2I6PES7	Staphylococcus_phage	1.5e-273	100.0
WP_000429558.1\|1613557_1615468_-	minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
WP_000179858.1\|1615483_1615774_-	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
WP_000384474.1\|1615773_1617357_-\|tail	phage tail protein	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
WP_001190533.1\|1617365_1618190_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_001003408.1\|1618189_1624390_-\|tail	phage tail tape measure protein	A0A1X9IGU9	Staphylococcus_phage	0.0e+00	99.7
WP_000438833.1\|1624403_1624562_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589167.1\|1624603_1624954_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000169127.1\|1625011_1625467_-	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
WP_000807536.1\|1625558_1626200_-\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_001023806.1\|1626234_1626630_-	DUF3168 domain-containing protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
WP_000110023.1\|1626630_1627032_-	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
WP_000395498.1\|1627028_1627361_-	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
WP_000050973.1\|1627372_1627651_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_001142734.1\|1627719_1628883_-\|capsid	phage major capsid protein	A0A2I6PEQ3	Staphylococcus_phage	1.2e-217	100.0
WP_000061866.1\|1628894_1629668_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
WP_001100664.1\|1629651_1630890_-\|portal	phage portal protein	A0A2I6PER5	Staphylococcus_phage	6.9e-235	100.0
WP_000153540.1\|1630894_1632586_-\|terminase	terminase large subunit	A0A1X9IGU0	Staphylococcus_phage	0.0e+00	100.0
WP_000778933.1\|1632575_1632881_-\|terminase	P27 family phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
WP_000160686.1\|1633007_1633322_-	HNH endonuclease	A0A2I6PEN4	Staphylococcus_phage	5.0e-57	100.0
WP_000528512.1\|1633478_1633916_-	transcriptional regulator	A0A2I6PEN3	Staphylococcus_phage	7.9e-77	100.0
WP_001801648.1\|1633928_1635296_-	DEAD/DEAH box helicase	A0A2I6PE95	Staphylococcus_phage	3.0e-263	99.8
WP_001548892.1\|1635276_1635567_-	VRR-NUC domain-containing protein	A0A2I6PE31	Staphylococcus_phage	6.5e-51	100.0
WP_001801650.1\|1635700_1635799_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	3.7e-11	100.0
WP_000884870.1\|1635907_1638355_-	virulence-associated E family protein	A0A2I6PEP4	Staphylococcus_phage	0.0e+00	100.0
WP_000265252.1\|1638642_1638843_-	DUF1514 family protein	A0A2I6PEP5	Staphylococcus_phage	4.9e-26	100.0
WP_000595263.1\|1638910_1639063_-	transcriptional activator RinB	A0A2I6PEM5	Staphylococcus_phage	2.0e-19	100.0
WP_000592202.1\|1639059_1639446_-	hypothetical protein	A0A1X9IGZ2	Staphylococcus_phage	3.0e-64	100.0
WP_000608275.1\|1639438_1639675_-	hypothetical protein	A0A2I6PEM4	Staphylococcus_phage	2.8e-36	100.0
WP_000141180.1\|1639667_1639871_-	hypothetical protein	A0A2I6PEQ8	Staphylococcus_phage	3.4e-30	100.0
WP_000195794.1\|1639867_1640074_-	DUF1381 domain-containing protein	A0A2I6PEM9	Staphylococcus_phage	1.6e-19	100.0
WP_000185671.1\|1640110_1640647_-	dUTP diphosphatase	A0A2I6PEN6	Staphylococcus_phage	1.6e-95	100.0
WP_001065039.1\|1640639_1640888_-	DUF1024 family protein	A0A2I6PEP2	Staphylococcus_phage	1.4e-38	100.0
WP_000132194.1\|1640902_1641145_-	hypothetical protein	A0A2I6PEV3	Staphylococcus_phage	1.5e-40	100.0
WP_000235324.1\|1641159_1641360_-	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
WP_000022728.1\|1641362_1641620_-	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
WP_000113974.1\|1641619_1642021_-	PVL family protein	A0A2I6PEL5	Staphylococcus_phage	1.2e-68	100.0
WP_001164629.1\|1642020_1642206_-	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_001801657.1\|1642218_1644171_-	DNA polymerase	A0A2I6PEL4	Staphylococcus_phage	0.0e+00	100.0
WP_000645048.1\|1644238_1644796_-	DUF2815 family protein	A0A2I6PEP8	Staphylococcus_phage	1.8e-97	100.0
WP_000762552.1\|1644821_1645988_-	DUF2800 domain-containing protein	A0A2I6PEL9	Staphylococcus_phage	1.4e-221	100.0
WP_000985979.1\|1645984_1646347_-	hypothetical protein	A0A2I6PEM7	Staphylococcus_phage	3.7e-56	100.0
WP_000291481.1\|1646360_1646621_-	DUF1108 family protein	A0A2I6PEM2	Staphylococcus_phage	3.4e-43	100.0
WP_000163431.1\|1646625_1646928_-	DUF2482 family protein	A0A1X9IGX2	Staphylococcus_phage	2.4e-48	100.0
WP_000829612.1\|1646920_1647238_-	hypothetical protein	A0A2I6PEL3	Staphylococcus_phage	1.1e-35	100.0
WP_001124198.1\|1647503_1647767_-	helix-turn-helix domain-containing protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
WP_001036299.1\|1647791_1648007_-	hypothetical protein	A0A2I6PEK7	Staphylococcus_phage	1.0e-32	100.0
WP_001548903.1\|1648053_1648293_+	hypothetical protein	A0A2I6PE22	Staphylococcus_phage	6.7e-38	100.0
WP_001001356.1\|1648289_1648466_-	hypothetical protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
WP_001115060.1\|1648549_1648741_-	helix-turn-helix transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
WP_000429766.1\|1648901_1649231_+	helix-turn-helix transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
WP_000525001.1\|1649243_1649705_+	hypothetical protein	A0A2I6PEK4	Staphylococcus_phage	2.9e-85	98.7
WP_000755722.1\|1649722_1650157_+	hypothetical protein	A0A2I6PEM0	Staphylococcus_phage	3.6e-21	96.5
WP_000449655.1\|1650185_1650581_+	hypothetical protein	A0A2I6PEJ7	Staphylococcus_phage	3.8e-70	100.0
WP_001795334.1\|1650670_1650817_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.2e-16	100.0
WP_000191466.1\|1650813_1651428_-	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
WP_000264751.1\|1651553_1652759_+\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
1652764:1652784	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1713577 : 1721889

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1713577_1714363_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924214.1\|1714488_1715379_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062180.1\|1715388_1716735_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
WP_000683931.1\|1716848_1717949_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624584.1\|1717951_1718629_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1718759_1719866_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217261.1\|1720089_1721889_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0

DBSCAN-SWA_7

1791026 : 1800069

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1791026_1791545_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594993.1\|1791566_1793840_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
WP_000749795.1\|1794042_1796322_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1796596_1796857_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1796875_1798015_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019172.1\|1798037_1799063_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1799064_1800069_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1925530 : 2004862

Staphylococcus_phage(94.83%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050549.1\|1925530_1932091_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	2.0e-304	98.1
WP_000836465.1\|1932416_1932728_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001549041.1\|1932749_1935167_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
WP_001025061.1\|1935454_1936636_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526539.1\|1936745_1937699_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1937695_1938259_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1938378_1938780_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1940358_1941186_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1941188_1941308_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1941419_1942421_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|1942542_1943007_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159022.1\|1943019_1944201_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_000493892.1\|1944211_1944844_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_000077344.1\|1944850_1945894_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.3e-197	99.4
WP_001261677.1\|1946374_1947877_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000221179.1\|1948399_1948714_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989121.1\|1948713_1950006_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_000163235.1\|1950023_1950419_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
WP_001032833.1\|1950713_1951568_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1951843_1952068_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1952266_1952737_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1952849_1953293_+	competence protein ComK	NA	NA	NA	NA
WP_001030465.1\|1953279_1953723_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
WP_001168904.1\|1954018_1954654_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096459.1\|1955093_1955807_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1956066_1956369_+	hypothetical protein	NA	NA	NA	NA
WP_001200541.1\|1956624_1956990_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	1.4e-58	99.2
WP_000623471.1\|1956986_1957340_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453320.1\|1959422_1960256_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
WP_000366154.1\|1960467_1961376_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
WP_000933822.1\|1961500_1962694_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109906.1\|1963064_1964657_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_000639100.1\|1964792_1965194_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	5.7e-13	36.3
WP_002868962.1\|1965652_1966399_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.1e-142	98.4
WP_000672014.1\|1966403_1966877_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_000718107.1\|1966942_1967200_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778523.1\|1967196_1968198_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
WP_000348360.1\|1968202_1969681_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
WP_011443643.1\|1969839_1970295_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
WP_001795535.1\|1970597_1971248_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_000070653.1\|1971328_1972324_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
WP_000627551.1\|1973066_1973411_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
WP_000414205.1\|1973508_1974060_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
WP_000494956.1\|1974277_1974919_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
WP_000809857.1\|1975032_1975218_-	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|1975219_1975396_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1975406_1975790_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|1976393_1976537_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_001801861.1\|1976739_1976835_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791893.1\|1976957_1977059_+	hypothetical protein	NA	NA	NA	NA
WP_001037045.1\|1977406_1977784_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000831218.1\|1978304_1982417_-	ATP-binding protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	100.0
WP_000072576.1\|1983266_1984466_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	5.5e-229	99.7
WP_000028659.1\|1984458_1986015_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.3e-288	99.4
WP_001791797.1\|1986178_1986313_-	hypothetical protein	NA	NA	NA	NA
WP_001038688.1\|1986377_1987097_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_001038759.1\|1987247_1987964_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
WP_011447030.1\|1988065_1988173_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1988121_1988841_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038867.1\|1988961_1989681_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
WP_001039447.1\|1989738_1990461_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
WP_001039435.1\|1990585_1991293_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.6e-130	100.0
WP_001092763.1\|1992256_1992823_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_000586140.1\|1993296_1993995_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_000581552.1\|1993991_1994753_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|1994749_1995442_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|1995464_1996838_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|1996847_1997366_-	flavoprotein	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000566596.1\|1997381_1998626_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_001092605.1\|1998618_2001612_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.3
WP_000416756.1\|2001676_2001820_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_000416759.1\|2002556_2002700_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000782464.1\|2002941_2003925_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000473596.1\|2003926_2004862_-	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0

DBSCAN-SWA_9

2089930 : 2186366

117

Staphylococcus_phage(91.03%)

tRNA,terminase,protease,portal,head,capsid,tail,holin,integrase

attL 2151356:2151373|attR 2176288:2176305

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000027928.1\|2089930_2091388_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|2091389_2091692_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957015.1\|2092058_2093597_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831698.1\|2093685_2094885_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774565.1\|2094897_2096901_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
WP_000992921.1\|2096904_2099097_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272069.1\|2099093_2099786_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|2099957_2100260_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|2100368_2101664_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827748.1\|2102524_2103691_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434933.1\|2103721_2104048_+	staphostatin A	NA	NA	NA	NA
WP_000669862.1\|2104339_2104513_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011538.1\|2104493_2105096_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040873.1\|2105366_2106188_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.8e-69	52.7
WP_000284431.1\|2106180_2107650_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.5e-108	45.1
WP_000897635.1\|2107833_2108910_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177817.1\|2108929_2109724_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2109795_2109903_+	hypothetical protein	NA	NA	NA	NA
WP_000323167.1\|2109913_2111476_-	SLC13 family permease	NA	NA	NA	NA
WP_000275730.1\|2111680_2112778_-	pectate lyase	U5PWM6	Bacillus_phage	1.9e-47	34.6
WP_000149686.1\|2113149_2113710_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2113762_2114692_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2114886_2115060_-	hypothetical protein	NA	NA	NA	NA
WP_001021214.1\|2115111_2116491_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181322.1\|2116610_2117639_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2117908_2118310_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2118882_2119056_-	hypothetical protein	NA	NA	NA	NA
WP_001188077.1\|2119506_2120547_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1\|2120603_2121446_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2121442_2122000_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2122059_2122584_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2122704_2123268_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221651.1\|2123333_2124074_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|2124073_2124946_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645727.1\|2124942_2125623_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991302.1\|2125623_2126520_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|2126516_2126897_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2127160_2127337_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2127579_2127678_-	hypothetical protein	NA	NA	NA	NA
WP_001068542.1\|2127877_2129164_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_050961220.1\|2129788_2131543_-	extracellular adherence protein Eap/Map	NA	NA	NA	NA
WP_000669789.1\|2132500_2132680_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001791826.1\|2132990_2133251_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|2133303_2133654_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_000727649.1\|2134338_2134788_+	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
WP_000919350.1\|2135867_2136359_-	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
WP_000861038.1\|2136549_2137305_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000611512.1\|2137316_2137571_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_001791821.1\|2137622_2137730_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1\|2137782_2137959_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_000539688.1\|2138108_2138405_-	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_001040261.1\|2138462_2138750_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_001153681.1\|2138796_2138949_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_000582165.1\|2138938_2142724_-	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.5
WP_000567394.1\|2142739_2144224_-\|tail	phage tail family protein	A0A0H3U501	Staphylococcus_phage	2.0e-297	100.0
WP_001549166.1\|2144220_2148750_-\|tail	phage tail tape measure protein	A0A1X9H084	Staphylococcus_phage	0.0e+00	95.0
WP_001549167.1\|2148806_2148944_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
WP_001096354.1\|2148994_2149345_-	hypothetical protein	A0A0H3U503	Staphylococcus_phage	1.3e-58	100.0
WP_094969769.1\|2149394_2149634_-	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	4.0e-30	94.6
WP_000260578.1\|2149660_2150305_-\|tail	phage tail protein	A0A0H3U4E6	Staphylococcus_phage	6.5e-120	100.0
WP_000565500.1\|2150308_2150713_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	1.4e-67	95.5
WP_000114229.1\|2150709_2151114_-	HK97 gp10 family phage protein	A0A0H3U2V1	Staphylococcus_phage	8.7e-70	100.0
WP_000755150.1\|2151110_2151473_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2151356:2151373	attL	NA	NA	NA	NA
WP_000150936.1\|2151456_2151741_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|2151730_2152015_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154559.1\|2152034_2153180_-\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
WP_000642728.1\|2153203_2153941_-\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_000025274.1\|2153924_2155112_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1\|2155127_2156789_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|2156785_2157130_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988336.1\|2157260_2157560_-	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
WP_000590122.1\|2157791_2158208_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000265043.1\|2158235_2158436_-	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
WP_000595265.1\|2158435_2158585_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000592207.1\|2158581_2158968_-	hypothetical protein	W5R986	Staphylococcus_phage	3.0e-64	100.0
WP_000195803.1\|2158964_2159171_-	DUF1381 domain-containing protein	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
WP_001282074.1\|2159167_2159413_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_000181819.1\|2159449_2159983_-	dUTP pyrophosphatase	A0A0H3U2T1	Staphylococcus_phage	1.6e-95	100.0
WP_000700108.1\|2159975_2160218_-	hypothetical protein	A0A2I6PF40	Staphylococcus_phage	3.7e-36	100.0
WP_001065101.1\|2160207_2160444_-	DUF1024 family protein	A0A0H3U313	Staphylococcus_phage	5.3e-35	100.0
WP_001549172.1\|2160436_2160808_-	hypothetical protein	A0A0H3U4X7	Staphylococcus_phage	4.7e-54	97.3
WP_000131383.1\|2160816_2161059_-	hypothetical protein	A0A0H3U4B0	Staphylococcus_phage	1.1e-40	100.0
WP_000101288.1\|2161062_2161431_-	hypothetical protein	A0A0H3U2T3	Staphylococcus_phage	2.0e-49	100.0
WP_000401977.1\|2161443_2161848_-	RusA family crossover junction endodeoxyribonuclease	A0A0H3U2W2	Staphylococcus_phage	1.4e-72	100.0
WP_000338530.1\|2161856_2162075_-	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.0e-37	100.0
WP_000148333.1\|2162081_2162975_-	DnaD domain-containing protein	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
WP_050961221.1\|2163004_2163475_-	single-stranded DNA-binding protein	A0A0H3U4B5	Staphylococcus_phage	2.8e-80	99.4
WP_071665632.1\|2163475_2164093_-	MBL fold metallo-hydrolase	A0A0H3U2T4	Staphylococcus_phage	4.1e-87	100.0
WP_000138475.1\|2164173_2165094_-	recombinase RecT	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_000700561.1\|2165095_2167039_-	AAA family ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	94.7
WP_001205732.1\|2167047_2167311_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291513.1\|2167319_2167580_-	DUF1108 family protein	A0A0H3U2T6	Staphylococcus_phage	6.8e-44	100.0
WP_001549178.1\|2167619_2167880_-	DUF2482 family protein	A0A0H3U2W4	Staphylococcus_phage	9.3e-41	100.0
WP_001285960.1\|2167974_2168136_-	DUF1270 domain-containing protein	A0A0H3U4Y7	Staphylococcus_phage	3.8e-21	100.0
WP_001120199.1\|2168132_2168453_-	DUF771 domain-containing protein	A0A0H3U4C3	Staphylococcus_phage	1.5e-56	100.0
WP_000549548.1\|2168511_2168742_+	hypothetical protein	A0A0H3U2T9	Staphylococcus_phage	9.4e-37	100.0
WP_001001356.1\|2168738_2168915_-	hypothetical protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
WP_001148642.1\|2168930_2169683_-	phage antirepressor KilAC domain-containing protein	A0A0H3U319	Staphylococcus_phage	5.6e-139	100.0
WP_000180411.1\|2169733_2170063_+	hypothetical protein	A0A0H3U4Z1	Staphylococcus_phage	4.6e-53	100.0
WP_001025404.1\|2170051_2170267_-	DUF2829 domain-containing protein	A0A0H3U4C7	Staphylococcus_phage	4.8e-35	100.0
WP_000854072.1\|2170282_2170546_-	helix-turn-helix transcriptional regulator	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
WP_001801500.1\|2170542_2170716_-	hypothetical protein	NA	NA	NA	NA
WP_001031454.1\|2170678_2171392_+	helix-turn-helix transcriptional regulator	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
WP_000759682.1\|2171407_2172340_+	ATP-dependent helicase	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
WP_000591749.1\|2172345_2172687_+	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
WP_000705246.1\|2172890_2173073_+	hypothetical protein	A0A0H3U4Z4	Staphylococcus_phage	4.1e-27	100.0
WP_001549185.1\|2173150_2173864_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A1X9H026	Staphylococcus_phage	5.0e-129	100.0
WP_000857199.1\|2174054_2175092_+\|integrase	site-specific integrase	A0A1X9H022	Staphylococcus_phage	3.8e-178	99.7
WP_000595324.1\|2176210_2177227_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	1.1e-25	29.0
2176288:2176305	attR	NA	NA	NA	NA
WP_000791407.1\|2177248_2178304_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
WP_000206639.1\|2178738_2179962_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_000812010.1\|2180333_2181179_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000825510.1\|2181240_2182152_-	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001045079.1\|2182312_2183620_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000022887.1\|2184472_2184916_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001797573.1\|2185080_2185458_-	hypothetical protein	NA	NA	NA	NA
WP_001293058.1\|2185775_2186366_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.1e-97	95.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP014431

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP014429

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection