CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP020005	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence	0 crisprs	RT,cas14j,csa3	0	1
NZ_CP020003	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed1, complete sequence	0 crisprs	NA	0	1
NZ_CP020004	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed2, complete sequence	0 crisprs	NA	0	1
NZ_CP020002	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 chromosome, complete genome	4 crisprs	cas3,cas14k,csa3,WYL,c2c9_V-U4,c2c10_CAS-V-U3,DinG,RT,DEDDh	3	14

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

286941 : 390338

Bacillus_phage(25.0%)

holin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079246636.1\|286941_288153_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.0e-61	33.4
WP_079246637.1\|288624_288990_-	hypothetical protein	NA	NA	NA	NA
WP_079246638.1\|290269_290647_-	hypothetical protein	NA	NA	NA	NA
WP_053514609.1\|291729_291963_+	hypothetical protein	A0A1B1P887	Bacillus_phage	1.2e-20	66.2
WP_079246639.1\|292052_292673_-	hypothetical protein	NA	NA	NA	NA
WP_053514610.1\|293220_293598_-	hypothetical protein	NA	NA	NA	NA
WP_053514612.1\|296235_296424_+	hypothetical protein	NA	NA	NA	NA
WP_079246640.1\|297327_297504_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_079245583.1\|297687_300660_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	4.6e-75	25.5
WP_079246294.1\|300761_301157_+	hypothetical protein	NA	NA	NA	NA
WP_079245584.1\|301266_302649_-	MmcB family DNA repair protein	NA	NA	NA	NA
WP_079245585.1\|302890_303460_+	recombinase family protein	A0A1V0E035	Clostridioides_phage	1.5e-30	39.3
WP_079246641.1\|303487_304009_-	DedA family protein	NA	NA	NA	NA
WP_079246643.1\|305617_306340_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	4.3e-19	31.0
WP_079246645.1\|306901_307453_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.7e-44	52.8
WP_079246646.1\|311006_312422_+	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_001100112.1\|314852_315032_+	hypothetical protein	NA	NA	NA	NA
WP_079245377.1\|315205_316513_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	6.6e-26	29.7
WP_001100112.1\|318484_318664_+	hypothetical protein	NA	NA	NA	NA
WP_079246647.1\|323169_325557_+	vegetative insecticidal protein Vip3A family protein	NA	NA	NA	NA
WP_079246648.1\|326925_327420_+	cation:proton antiporter regulatory subunit	NA	NA	NA	NA
WP_079246649.1\|327424_328624_+	cation:proton antiporter	NA	NA	NA	NA
WP_079246650.1\|329104_330061_+	N-acetylmuramoyl-L-alanine amidase	A0A1J0MS59	Bacillus_phage	1.4e-49	44.4
WP_079246651.1\|330350_333896_+	pesticidal protein	NA	NA	NA	NA
WP_079246652.1\|334402_336562_+	pesticidal protein	NA	NA	NA	NA
WP_014481901.1\|336776_337883_-	tyrosine recombinase XerS	A0A1B1IQT7	uncultured_Mediterranean_phage	2.0e-07	28.4
WP_079246653.1\|338048_339074_-	macro domain-containing protein	A0A2I7QNM6	Vibrio_phage	5.5e-20	38.3
WP_079246654.1\|339088_339721_-	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_014481901.1\|339880_340987_+	tyrosine recombinase XerS	A0A1B1IQT7	uncultured_Mediterranean_phage	2.0e-07	28.4
WP_079246655.1\|347698_348655_-	N-acetylmuramoyl-L-alanine amidase	A0A0S2MV84	Bacillus_phage	5.3e-49	39.5
WP_001035125.1\|353087_353618_-	ABC transporter permease	NA	NA	NA	NA
WP_079246656.1\|354001_357697_-	pesticidal protein	NA	NA	NA	NA
WP_033698205.1\|358399_358651_-	hypothetical protein	NA	NA	NA	NA
WP_079246657.1\|358984_359407_-\|holin	phage holin family protein	A0A0S2MVC4	Bacillus_phage	3.5e-53	77.3
WP_033698201.1\|361307_361712_-	DUF3221 domain-containing protein	NA	NA	NA	NA
WP_053512358.1\|362420_363470_+	Fic family protein	NA	NA	NA	NA
WP_000954718.1\|363717_364560_-	N-hydroxyarylamine O-acetyltransferase	NA	NA	NA	NA
WP_016078253.1\|368056_369190_-	alpha-helical pore-forming toxin family protein	NA	NA	NA	NA
WP_079246659.1\|369221_370451_-	alpha-helical pore-forming toxin family protein	NA	NA	NA	NA
WP_060852712.1\|370512_371832_-	HBL/NHE enterotoxin family protein	NA	NA	NA	NA
WP_003308422.1\|375475_376471_-	DUF4046 domain-containing protein	NA	NA	NA	NA
WP_153594277.1\|379456_379627_+	hypothetical protein	NA	NA	NA	NA
WP_033700259.1\|380890_381784_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_001043045.1\|382824_383079_+	HU family DNA-binding protein	A3E2K9	Sodalis_phage	1.2e-13	48.9
WP_000448514.1\|383131_383323_-	hypothetical protein	NA	NA	NA	NA
WP_145953776.1\|383624_384772_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.4e-48	41.8
WP_003308343.1\|387635_387887_-	hypothetical protein	NA	NA	NA	NA
WP_079246660.1\|389108_390338_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	4.4e-80	49.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP020002

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020002_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020002_1

626196-626271

Orphan

Consensus_repeat	Method
ATCATCATCATGGAGGACACAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020002_1

>merge|NZ_CP020002|1|626196-626271|CRISPRCasFinder
ATCATCATCATGGAGGACACAATCATGGTGGGCACAATCATAACGGCGGACATCATCACCATGGAGGACACAATCA

>NZ_CP020002|1|1|626196-626271|CRISPRCasFinder
ATCATCATCATGGAGGACACAATCA	TGGTGGGCACAATCATAACGGCGGAC
ATCATCACCATGGAGGACACAATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020002.1\|WP_001167972.1\|616989_617811_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_CP020002.1\|WP_000095901.1\|618787_619978_+\|glycine-C-acetyltransferase	unknown	unknown	gnl\|CDD\|235893
NZ_CP020002.1\|WP_000987242.1\|630579_631290_+\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NZ_CP020002.1\|WP_044783725.1\|636759_638262_-\|spore-germination-protein-GerKA	unknown	unknown	gnl\|CDD\|377020
NZ_CP020002.1\|WP_000760052.1\|615918_616977_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP020002.1\|WP_079245063.1\|632873_634535_+\|alpha,alpha-phosphotrehalase	unknown	unknown	gnl\|CDD\|274115
NZ_CP020002.1\|WP_000513939.1\|631432_632860_+\|PTS-system-trehalose-specific-EIIBC-component	unknown	unknown	gnl\|CDD\|273916
NZ_CP020002.1\|WP_044783724.1\|635672_636779_-\|GerAB/ArcD/ProY-family-transporter	unknown	unknown	gnl\|CDD\|281794
NZ_CP020002.1\|WP_000885973.1\|617842_618574_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP020002.1\|WP_000723120.1\|620022_620988_+\|L-threonine-3-dehydrogenase	unknown	unknown	gnl\|CDD\|187580
NZ_CP020002.1\|WP_000448446.1\|628729_630127_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129983
NZ_CP020002.1\|WP_001248845.1\|621507_623391_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|226921
NZ_CP020002.1\|WP_000401662.1\|638450_639422_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|225213
NZ_CP020002.1\|WP_000925213.1\|614917_615922_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP020002.1\|WP_000893348.1\|626994_628698_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NZ_CP020002.1\|WP_079245064.1\|639581_641042_+\|alanine:cation-symporter-family-protein	unknown	unknown	gnl\|CDD\|376500
NZ_CP020002.1\|WP_001189930.1\|621047_621470_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239217
NZ_CP020002.1\|WP_000743027.1\|624415_625945_-\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|171510
NZ_CP020002.1\|WP_044783723.1\|634567_635692_-\|Ger(x)C-family-spore-germination-protein	unknown	unknown	gnl\|CDD\|274338
NZ_CP020002.1\|WP_000892989.1\|623394_624288_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786

Protein	Function_ID	Function_description	E-value
NZ_CP020002.1\|WP_001167972.1\|616989_617811_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	8.44295e-133
NZ_CP020002.1\|WP_000095901.1\|618787_619978_+\|glycine-C-acetyltransferase	gnl\|CDD\|235893	PRK06939, PRK06939, 2-amino-3-ketobutyrate coenzyme A ligase; Provisional.	0
NZ_CP020002.1\|WP_000987242.1\|630579_631290_+\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	1.60325e-130
NZ_CP020002.1\|WP_044783725.1\|636759_638262_-\|spore-germination-protein-GerKA	gnl\|CDD\|377020	pfam03323, GerA, Bacillus/Clostridium GerA spore germination protein.	0
NZ_CP020002.1\|WP_000760052.1\|615918_616977_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	8.98999e-88
NZ_CP020002.1\|WP_079245063.1\|632873_634535_+\|alpha,alpha-phosphotrehalase	gnl\|CDD\|274115	TIGR02403, Trehalose-6-phosphate_hydrolase, alpha,alpha-phosphotrehalase. Trehalose is a glucose disaccharide that serves in many biological systems as a compatible solute for protection against hyperosmotic and thermal stress. This family describes trehalose-6-phosphate hydrolase, product of the treC (or treA) gene, which is often found together with a trehalose uptake transporter and a trehalose operon repressor.	0
NZ_CP020002.1\|WP_000513939.1\|631432_632860_+\|PTS-system-trehalose-specific-EIIBC-component	gnl\|CDD\|273916	TIGR01992, phosphotransferase_system_trehalose_permease, PTS system, trehalose-specific IIBC component. This model represents the fused enzyme II B and C components of the trehalose-specific PTS sugar transporter system. Trehalose is converted to trehalose-6-phosphate in the process of translocation into the cell. These transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci and Streptococci which contain their own A domain as a C-terminal fusion. This family is closely related to the sucrose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively). In E. coli, B. subtilis and P. fluorescens the presence of this gene is associated with the presence of trehalase which degrades T6P to glucose and glucose-6-P. Trehalose may also be transported (in Salmonella) via the mannose PTS or galactose permease systems, or (in Sinorhizobium, Thermococcus and Sulfolobus, for instance) by ABC transporters.	0
NZ_CP020002.1\|WP_044783724.1\|635672_636779_-\|GerAB/ArcD/ProY-family-transporter	gnl\|CDD\|281794	pfam03845, Spore_permease, Spore germination protein.	4.68428e-41
NZ_CP020002.1\|WP_000885973.1\|617842_618574_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.07831e-20
NZ_CP020002.1\|WP_000723120.1\|620022_620988_+\|L-threonine-3-dehydrogenase	gnl\|CDD\|187580	cd05272, TDH_SDR_e, L-threonine dehydrogenase, extended (e) SDRs. This subgroup contains members identified as L-threonine dehydrogenase (TDH). TDH catalyzes the zinc-dependent formation of 2-amino-3-ketobutyrate from L-threonine via NAD(H)-dependent oxidation. This group is distinct from TDHs that are members of the medium chain dehydrogenase/reductase family. This group has the NAD-binding motif and active site tetrad of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NZ_CP020002.1\|WP_000448446.1\|628729_630127_-\|amino-acid-permease	gnl\|CDD\|129983	TIGR00905, Arginine/ornithine_antiporter, transporter, basic amino acid/polyamine antiporter (APA) family. This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines].	1.33606e-97
NZ_CP020002.1\|WP_001248845.1\|621507_623391_-\|VWA-domain-containing-protein	gnl\|CDD\|226921	COG4548, NorD, Nitric oxide reductase activation protein [Inorganic ion transport and metabolism].	1.51306e-97
NZ_CP020002.1\|WP_000401662.1\|638450_639422_+\|phosphotransferase	gnl\|CDD\|225213	COG2334, COG2334, Putative homoserine kinase type II (protein kinase fold) [General function prediction only].	2.61331e-33
NZ_CP020002.1\|WP_000925213.1\|614917_615922_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	6.49512e-87
NZ_CP020002.1\|WP_000893348.1\|626994_628698_+\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	2.99317e-109
NZ_CP020002.1\|WP_079245064.1\|639581_641042_+\|alanine:cation-symporter-family-protein	gnl\|CDD\|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	0
NZ_CP020002.1\|WP_001189930.1\|621047_621470_+\|NUDIX-hydrolase	gnl\|CDD\|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	1.7486e-24
NZ_CP020002.1\|WP_000743027.1\|624415_625945_-\|cardiolipin-synthase	gnl\|CDD\|171510	PRK12452, PRK12452, cardiolipin synthase.	0
NZ_CP020002.1\|WP_044783723.1\|634567_635692_-\|Ger(x)C-family-spore-germination-protein	gnl\|CDD\|274338	TIGR02887, Spore_germination_protein_B3, germination protein, Ger(x)C family. Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination].	5.06149e-94
NZ_CP020002.1\|WP_000892989.1\|623394_624288_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	6.9487e-37

>NZ_CP020002.1|WP_000743027.1|624415_625945_-|cardiolipin-synthase
MKKPIVQLLLIFTIVSIVLFLLNTSYISLYTFVGALWSITIVGISFVIFIENRSPQSTLAWFLVLALLPIIGVLLYAIFGRSRWRRKKHLHRSEEQRKLFREILEGRRLELLLTVPLNERSIHLTEVIQKFGGGPAADKTTTKLLTNGDQTFSEILRAIEQAKHHIHIQYYIYKSDEIGTKVRDALIQKAKDGVIVRFLYDGLGSNTLRRRFLQPMKEAGIEIVEFDPIFSAWLLETVNYRNHRKIVIVDGEIGFTGGLNVGDEYLGRSKKFPVWRDSHLKIEGKALYKLQAIFLEDWLYASSGLNTYSWDQFMNRQYFPGKEISHAEGAVQIVASGPSSDDKSIRNTLLAVMGSAKKSIWIATPYFIPDQETLTLLRLSAIAGIDVRILYPGKSDSIISDQASQSYFTPLLKAGASIYSYKDGFMHAKIVLVDDTIATIGTANMDVRSFELNYEIISVLYESKTVHDIKRDFEKDFKHSTEIKWNSFQKRSIKKRILESFMRLISPLL
>NZ_CP020002.1|WP_000892989.1|623394_624288_-|MoxR-family-ATPase
MLEQFHIHSDLKQQLSTIHEKNKQEAGENAHLIGTKIYKASDNSIIEDAITALLLGKNILLKGPTGSGKTVLAETLSSLFQKPMHSINCSVDLDVEGILGYNTLQTKDGASEVSFVNGPLMKAMKNGHFLYIDEINMAKPETLPLLHGALDYRKMITNPFTQEVVYGDEEYRVIAAINEGYVGTSELNEALKNRFVIIEVPYIQGDTLKELLLAESKLNDVATIEKFVAFASDLMPLARDGRVSEEAASIRGIIDACDLGVYIPVMRAIERSIIAKLNDETEQMTVRELAESYFFEG
>NZ_CP020002.1|WP_001248845.1|621507_623391_-|VWA-domain-containing-protein
MRQIFSDKKIDASLFLQMENLMYALLKEDDAYLEYGYKAYYDEIEKKVVISHFWDDRKEEDTVIGLKSEVFLKALGNKHYSDMTLIRSYAIELQESPLKKFLTQLFVLLEDLRVEEIVKNLRPGTKHIFKRRKEMYRNYFGSQNEINRVRNYHGDRLFCLCYLSLTSDKYEMFNNEYFEQIEAILHETFQARNTEDIMYVVEKIRYRLEALLESDMLNNYFGHAPLYLSVLADEKNCRVEDLANDDTQLIDDDENKNKMDESFSTWHRENKNNENENFLRFELESGTKTNMMGDTARESEDGDQALGSVQGTSQKSTQSNFDGADTEEARASHASSQHDGAYGKYNVGASHTFKEARKANIDEKKDYQAIKSVVNKDVKELKKIIEKTIENKTNANSDKYYGRLRKKFLRIYTEKQPRMFYKKGQESQELDVAFQLLVDCSGSMYNKMEETKKSVVLFHEALKSLKIPHAISGFWEDASSAKPEDKPNVIHEVVNYKNSTLPNVGPEIMQLREEEDNRDGYIIRIVSEKLAKRPEKHKFLLVFTDGEPSALDYQQDGILDTHEAVKLARKSGMEVIGIFIEEGEAKEATYQLMKNIYNHHFLVANHAEDLRLKIKPLLKKLLLKTIE
>NZ_CP020002.1|WP_001189930.1|621047_621470_+|NUDIX-hydrolase
MQRVDVVYALIHDEETDKILMVHNAEQNVWSLPGGAVEKGEILEEALIREVKEETGLIATLGGLVAINEKFFEESGNHALFFTFRANVVKGELIAEDEGEISAIEWVDRTIANERFPYYDGGFESLLEVAIPYKFQPETK
>NZ_CP020002.1|WP_000723120.1|620022_620988_+|L-threonine-3-dehydrogenase
MKKILVTGSLGQIGSELVMKLRDVYGASNVIATDIRETDSEVVKSGPFETLDVTDGQKLHDIAKHNEVDTIIHLAALLSATAEKNPLFAWNLNMGGLVNALEAARELNCKFFTPSSIGAFGPSTPKDNTPQDTIQRPTTMYGVNKVAGELLCDYYHQKFGVDTRGVRFPGLISYVAPPGGGTTDYAVEIYYEAIKKGAYTSYIAEGTYMDMMYMPDALQAIISLMEADPSKLVHRNAFNITAMSFEPEQIAASIRKHIPTFTMDYAVDSARQTIADSWPNSIDATAAMKEWGFKAEYDLDKMTTDMLAKLKKKLTAELVMN
>NZ_CP020002.1|WP_000095901.1|618787_619978_+|glycine-C-acetyltransferase
MSSKTLAKFLEENLEDLKSKGLYNVIDPLESSNGPIITIGGKEYINLSSNNYLGLATDSRLQEAAIGAIHKYGVGAGAVRTINGTLDLHIKLEEIIAKFKHTEAAIAYQSGFNCNMAAISAVMDKNDAILSDELNHASIIDGSRLSKAKIIVYKHSDMEDLRQKAIAAKESGLYNKLMVITDGVFSMDGDVAKLPEIVEIAEELDLMTYVDDAHGSGVLGKGAGTVKHFGLSDKVDFQIGTLSKAIGVIGGYVAGKQNLIDWLKVRSRPFLFSTALTPADAAACMRSIEILMESTELHDRLWENGRYLKQGLKELGFNIGESETPITPCIIGDEVLTQEFSKRLNEEGVYAKSIVFPTVAKGKGRVRNMPTAAHTKEMLDEAIRKYEKVGKEMGII
>NZ_CP020002.1|WP_000885973.1|617842_618574_-|class-I-SAM-dependent-methyltransferase
MAFTESDVYNNTAFFEQYMKRRYRENSPNESIEKPVFFQLIGHVQGKQILDLGCGDAKFGAELLEKGCYSYTGIEGSELMYEKAKNQLENKNGSVHFLNLKDYTYPSSTFDLVTSRLALHYIEHLDTIFQNVFQTLKTNGTFTFSVQHPVITSSFESLQTSGKRTSWLVDDYFKLGKRVEPWIDQEVIKYHRTTEEYFTLLQQAGFTITSLKEATPNPIYFQNEEEYKRRLRIPLFLLFSCTK
>NZ_CP020002.1|WP_001167972.1|616989_617811_+|ABC-transporter-ATP-binding-protein
MQKALETKRLTLSYGETSIIDELNLEIPKGEITIFIGSNGCGKSTLLRSLARLLKPTTGDILLDNQAIQSMQTKQIARQMAILPQGPQAPEGLTVLQLVKQGRYPYQTWLKQWSEKDEEMVQKALAATGMTEFAERDVHALSGGQRQRAWIAMTLAQDTDIILLDEPTTYLDMTHQIEVLDLLFELNETEQRTIVMVLHDLNLACRYADNIVAIQDKQIYAQGKPEEVVDEKLVRDVFRMECQISTDPLFGTPLCIPHGRGRRVVKEVAQAIR
>NZ_CP020002.1|WP_000760052.1|615918_616977_+|iron-ABC-transporter-permease
MKKYIPFRIGKGELSFLMYKRACLVLLSLLLVLIGLFFASAGMGDMKIAPYDVWQAITGNGDAMSNMVVNKFRMPRILIAILVGIALAVAGCILQGLVRNPLASPDIIGITGGASVAVVLFLALFSDKNNALTVSIHYMPLAAFAGATIVAVFVYLFAWQNDGLSPISLVLIGVGFWALTKAATTLFMLLAPIYQASQANVWITGTVYGSSWQNVMVLAPWVLILTVISFIAARHLNAQELGDDIAVGLGVPLTKSRVFMLLLSTALIGGAVAFAGGIGFVGLMAPHISRRLVGSLYGALLPVAAIVGAILVLAADLIGRTIFTPLEIPAGVFTSAIGAPYFIYLLYKSRNS
>NZ_CP020002.1|WP_000925213.1|614917_615922_+|iron-ABC-transporter-permease
MLLKTNRAKGIGLFVGIIAVVICIWGSIIFGYTNTSWKLALDAFFHFNGSNEHIIIQNVRLPRALIAASVGASLAIAGCLMQTLTKNPLASPDFIGLNSGAAFFIVVAIVIFSVTSLSAFTWIAFLGAAVAAVLVFASSSLGKEGTTPLKLTLAGVAISALFSSLTQGLLVLNEKALEEVLFWLAGSVQGRKLEILQSVFPYLLIGWIASLIMAGKVNTLMMGEDVAKGLGQRTILMKSFVLLIIVLLSGGSVAVAGPIGFIGIITPHFARFLVGVDHRWRVPYSGLLGAILLILADIAARYVIMPQEVPVGVMTAFIGAPFFIYIARKRGLSK
>NZ_CP020002.1|WP_000893348.1|626994_628698_+|EAL-domain-containing-protein
MLEQRGHALYDSSLRDLKLALDESSIVAITDRKGLITYVNDKFCEISKYKREELIGKDHRILNSGHHPKTFFQNLWKRILNGKVWTGEIRNRAKDGTYYWVKTTIVPFLNEKGEPYQFIAIRNDISSRKEAEHRLRLSESRYRELAYHDALTSLPNRLQLITTVNKLIADKKEFGMIYFDLDRFKLVNDTLGHMIGDLLLSEVASRLHYVLGEKDVLARLGGDEFVLLTKNHRQDDMSQLATSVLSCFQAPFMLEGHEVYISASLGLCSYPQDGLDVETLLKNSDLAMYSAKEQGRNAACFFTDELRAKINRRMKVEFALQKAIRDEELDVALQPIIDLKTKRYSGIEALVRCMTEDGPIAPSEFIPVAEESGLIIKLGDWVLEKSCRLFKTLPNYQEGLKLSVNLSIQQLMQKRFILSVRSILKRTGFPPNRLILEITESIAVRHFDYIIATLQELRNMGVLIALDDFGTGYSSLYYLKQLPLDIVKIDRNFIREFHYDHAQPERTIVKSVIEIAHSLNLAVVAEGVETVEQESLLQSMSCDYVQGFYYAKPLSVGELKEKLITDF
>NZ_CP020002.1|WP_000448446.1|628729_630127_-|amino-acid-permease
METKKWGLWVLTAFVIGNMVGGGVFMLPANLAQVSGPMGSTLAWSITGLGVFMIALVFGNLAIRKPELKAGPQSYAQAMFPSKKAGKVAGYSMAWGYWAANWAATASVIISFAGYLSTFFPVLQSKQILFSINGFSLELGKGLTFLVCSLMLWGIQYILSQNIDRAGNMNLLATIAKIIGFTMFIVITLFIFNASNFGDGQTFMNEAGQSISLGGQINSAAIATLWAFIGIESAVMLSNRAKSQRDVKKATIFGLIIALLIYMSITLLTMGALPQDALKESQKPLVDALNLAIGNKGAYIMALLALISLFGSTVGWIVVSSEVPYQAAKNGLFPKFFGKTNKKGSPSKSLLITNVMTQIFLFSTISGTVSEAYSFAIVVATLAYLIPYLVSTLYQFKLVITGETYDIMPGSRIKDGIITTLAFVYSIWVIKTGTADLKTFFLGIGLFVLGLILYPVLMKDSQKTD
>NZ_CP020002.1|WP_000987242.1|630579_631290_+|trehalose-operon-repressor
MMSKYEQIYTEISKSIDNKQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKIHGKGVFVLKRKNIEFNFGGIVSFQEENERLGRHCITEVVEMDKEKATKEIAKLLNVKEKTEIDHIKRVRNIDGEKVILDINHFVSEFIPGLTKEIATASIYKYIEKELGLHISYSQRVIEVQPCTEDDRKYLDLNGTDYVVVVKNFTHLYDGSQFEYTESRHRLDIFHFSDVARRK
>NZ_CP020002.1|WP_000513939.1|631432_632860_+|PTS-system-trehalose-specific-EIIBC-component
MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDRVYAELITLAGMEESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLGGLWDLINMMANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLEGQKIEYFNILGLFQIEKVGYQGQILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMIIAVVIPFTLTWLFAKRVKQK
>NZ_CP020002.1|WP_079245063.1|632873_634535_+|alpha,alpha-phosphotrehalase
MKDWHKSVVYQIYPKSFNSYYNKETGDIKGVTEKLDYLKELGVDYIWLTPIYQSPQNDNGYDVSDYYSIDPSYGTMEEFEELLAEAKVRNIEIMLDIVVNHSSTEHKWFKEAKEDKNSPYRNYYIWRDEKNNWQSKFGGSAWKYDEKTEQYYLHLFDETQADLNWENEQLREEVYDMMRFWLDKGVTGLRLDVINLISKDQCFLNDEGNTATSDGRKYYTDGPRVHEYLQEMNRKVFAGKDVITVGEMSSTTIDNCIKYSNPERNELSMTFSFHHLKVDYPNGDKWTKAEFDFIKLKEIMSNWQIEMQKGGGWNALFWCNHDQPRIVSRFGDDRKYRNESAKMLATAMHMLQGTPYIYQGEEIGMTNPKFESIEQYRDVESLNIYDIKREEGLSKEEIIGILKQKSRDNSRTPMQWNEEMNSGFTTSTPWISVAENFTEINVEKALEDKESVFYHYKKLIELRKTYDVITEGEYAILDKNDPKIWAYTRTTESEVLLVINNFYGEEITYSVPAHVQLDGMKQEVLLSNYKDASKDIAKLNLRPYESIVYRYTK
>NZ_CP020002.1|WP_044783723.1|634567_635692_-|Ger(x)C-family-spore-germination-protein
MFKKRVKLLFLLCTSAFLSGCWDQEPLREARLAYSIGYDITEENKLQQTLELVKSSSGEQSSFENEVHSATGYNIRDTSDALKKNVTGNIRYFKYGVQLLGTKILKKGILPYLDVSFRDPTNPTALVKLIAVDGETSEILKKKKVGNLLIGDFLKKKVKSLEDMSVFPKETLETAATKMLDPGKDFTLPSIKIKEKEVITDGLSLFNKDKLTGHLPLKQSVLFVLLTGKMGTSARITQKLTSDESETTSDYLTMEISNRKLKRDLKITTDKKGNVYAHIKLQLKVIALEAPRDNLYKMWERKKLNKELSKQLTKEAKQITKKLQKANCDAFGIGRHLIAYHPELWRKKNWDKDYAKVKFKPEVEVSILYSGVLK
>NZ_CP020002.1|WP_044783724.1|635672_636779_-|GerAB/ArcD/ProY-family-transporter
MTNTQSKISLVQFTFFVIQCQIGVGILSLPNRLHPIAKGGGWISALIAGLAIQLIILLMWLFLKRFPDADMYESVCMLFGNKFGKLLGFAYVFYFTLIGMTVMLNACNVIKVWVLQATPWSAILILFTIACCYVAYNTFKVIVRFYVMASILILPMALLIALGFSRADFSYIFPITEAGWWNIIQASRETITAMYGFEIILIAFPKVNGSSVAKLKAISIANGFVTLFYTFTVWICFIVFSPKQVELIPEPVAYLLRSLHIGIIDRTDLLFIPIWMITVVASIASYYCAASIGIGHIFNLANHKKAVPIVGIIAFSVAVFIDTPEELKVIATFTDKFTYIFIVVLPLLFLLYSVIRNKKGEQYVQKKS
>NZ_CP020002.1|WP_044783725.1|636759_638262_-|spore-germination-protein-GerKA
MTERKEQQESKKQKHMFPSLPENINYIENKLSHSDDIKKLDIPFQNGKGIILYIESLADPNLIHQLVLEPLLTRSDLSLDKAFSTLNMKKETNLNYGVQLLLQGKSLYFHEHVESFCIFETALSLKRDITEPDNEGIVRGPHTGFVEDLATNLASIRKLIKSPNVVVKYFTLGEEMHTKVAIAYMQNIANDDLVTEVKRRLETIKTDALMPPGYIQEFIEDTSFSPFPQQLNTERPDRVAANLMEGRVAILSDGDPTALIVPVTLFAFYQSPDDYNNRWIVGSFVRMIRLVSFLIAFLLPAIYIATVAFHPDVLPLELVYTIKASLEKVPLPPIFEALLMELIFELLREAGIRLPSRVGQTIGIVGGLVIGDAIVKAGLVSYTMIIVVALTAISSFLVPSNDMSSAVRILRFPLMLLAAIFGYVGISFGLIITFVHLCQLHSFHTPYLSPVAPMRIKDMKDSFVRLPMWSFWERPHDPKPKKMQRQHVTREDEDGDKHAK
>NZ_CP020002.1|WP_000401662.1|638450_639422_+|phosphotransferase
MEIAVERVFTKEILRRAAKAFHVTVEEKPLGDFENYIFKAKGDNDEDYVLRLTHSSHRSKKEVEAELDFLRYVAEHGAKVAGPLNSTSQNLVEEIGAEDSTFFFASLFTYAKGEQVKGEGSPYWGDDYFEAWGKAIGQLHRLTMSYPKTDYRDTWEEDESGIVNELEDDQVKKIAAVLMDEIKALPVERETFGLMHGDIHPGNFHYDGKELTIFDFDDAAYNYFIHDLAMVLYYSILFTPWTAEEKTDFARKQLQVLRKGYEHEHRLADSWYESLPLFLRLRDVGLYGTLQKKFKGKGMPDNFRELSEELYERIIKREAIVNI
>NZ_CP020002.1|WP_079245064.1|639581_641042_+|alanine:cation-symporter-family-protein
MEAFVNSLNNIVWSPALVYLCLGVGLYFSIRTRFLQVRHVGEMVKLTFQGEKSEAGVSSFQALALSLSGRVGTGNIAGVATAVAFGGPGAVFWMWAVAFLGAGSAYIESTLAQIYKTKHQGQFRGGPAYYIEKGLGVKWYALVFVAATILATGLLLPGVQANSIAVSLETAFGINTTVSGALLVVVLAIIIFGGVKRIVNVAQVVVPFMAVGYILVACVIVAMNIEKLPEAFMLIIRSAFALEAAFGGIIGLAISWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFSVYIDTLFVCSATAFMMIITGMYNVFDASGKNFIVNKLNGAQPGPGYTQAAVESVFPGFGNGFVAISLLFFAFTTIMAYYYIAETNIAYLNRDKDRPWLSIVLKFVFLGAVFYGCIKTAATAWALGDIGVGIMAWVNIIAILLLQKPALVALKDYEKQKKEGKDPVFDPQPLGIKNADFWEHEYGKDKKEEVS

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Crispr_ID: NZ_CP020002_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020002_2

5240103-5240219

Orphan

Consensus_repeat	Method
CTTAAACAAGCGTTTGATTAATTCTCCATTTTTCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020002_2

>merge|NZ_CP020002|2|5240103-5240219|CRISPRCasFinder
CTTAAACAAGCGTTTGATTAATTCTCCATTTTTCTTCGTTAACCTTTGAACTACATGAGTTTCTTTCTACCGAACATACAGCTTAAACAAACGTTTGATTAATTCTCCATTTTTCTT

>NZ_CP020002|2|2|5240103-5240219|CRISPRCasFinder
CTTAAACAAGCGTTTGATTAATTCTCCATTTTTCTT	CGTTAACCTTTGAACTACATGAGTTTCTTTCTACCGAACATACAG
CTTAAACAAACGTTTGATTAATTCTCCATTTTTCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020002.1\|WP_001002987.1\|5243929_5244178_-\|spore-coat-protein	unknown	unknown	gnl\|CDD\|377935
NZ_CP020002.1\|WP_016099154.1\|5245699_5246248_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP020002.1\|WP_001232991.1\|5244520_5245234_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP020002.1\|WP_000026896.1\|5239116_5239500_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP020002.1\|WP_001242581.1\|5246251_5246974_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293807
NZ_CP020002.1\|WP_000713769.1\|5240990_5241638_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239481
NZ_CP020002.1\|WP_000218968.1\|5239541_5239907_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP020002.1\|WP_000826875.1\|5240318_5240846_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020002.1\|WP_106081637.1\|5242733_5243903_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|133427
NZ_CP020002.1\|WP_001242143.1\|5237232_5237577_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020002.1\|WP_000929162.1\|5232397_5233183_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP020002.1\|WP_000735090.1\|5234299_5235112_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP020002.1\|WP_000640870.1\|5238041_5238386_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224572
NZ_CP020002.1\|WP_079246114.1\|5233421_5234228_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP020002.1\|WP_017763726.1\|5235793_5236819_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP020002.1\|WP_001180555.1\|5244191_5244377_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020002.1\|WP_000666176.1\|5241697_5242711_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|379113
NZ_CP020002.1\|WP_000359401.1\|5235135_5235801_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP020002.1\|WP_000568179.1\|5237729_5238029_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP020002.1\|WP_002008874.1\|5247112_5248915_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173850

Protein	Function_ID	Function_description	E-value
NZ_CP020002.1\|WP_001002987.1\|5243929_5244178_-\|spore-coat-protein	gnl\|CDD\|377935	pfam07875, Coat_F, Coat F domain. The Coat F proteins, which contribute to the Bacillales spore coat. It occurs multiple times in the genomes it is found in.	9.62029e-15
NZ_CP020002.1\|WP_016099154.1\|5245699_5246248_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	8.86502e-26
NZ_CP020002.1\|WP_001232991.1\|5244520_5245234_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	4.36104e-17
NZ_CP020002.1\|WP_000026896.1\|5239116_5239500_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	6.96592e-70
NZ_CP020002.1\|WP_001242581.1\|5246251_5246974_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	6.69275e-73
NZ_CP020002.1\|WP_000713769.1\|5240990_5241638_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239481	cd03386, PAP2_Aur1_like, PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.	8.02684e-16
NZ_CP020002.1\|WP_000218968.1\|5239541_5239907_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	6.13259e-61
NZ_CP020002.1\|WP_017763726.1\|5235793_5236819_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.65905e-176
NZ_CP020002.1\|WP_106081637.1\|5242733_5243903_-\|L-lactate-dehydrogenase	gnl\|CDD\|133427	cd05291, HicDH_like, L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases. L-2-hydroxyisocapronate dehydrogenase (HicDH) catalyzes the conversion of a variety of 2-oxo carboxylic acids with medium-sized aliphatic or aromatic side chains. This subfamily is composed of HicDHs and some bacterial L-lactate dehydrogenases (LDH). LDHs catalyze the last step of glycolysis in which pyruvate is converted to L-lactate. Bacterial LDHs can be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. Members of this subfamily with known structures such as the HicDH of Lactobacillus confusus, the non-allosteric LDH of Lactobacillus pentosus, and the allosteric LDH of Bacillus stearothermophilus, show that they exist as homotetramers. The HicDH-like subfamily is part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP020002.1\|WP_000929162.1\|5232397_5233183_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	5.15323e-150
NZ_CP020002.1\|WP_000735090.1\|5234299_5235112_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	6.69253e-111
NZ_CP020002.1\|WP_000640870.1\|5238041_5238386_-\|hypothetical-protein	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.03274e-21
NZ_CP020002.1\|WP_079246114.1\|5233421_5234228_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.32546e-110
NZ_CP020002.1\|WP_000666176.1\|5241697_5242711_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	1.25572e-86
NZ_CP020002.1\|WP_000359401.1\|5235135_5235801_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	8.57648e-99
NZ_CP020002.1\|WP_000568179.1\|5237729_5238029_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.00054e-18
NZ_CP020002.1\|WP_002008874.1\|5247112_5248915_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	0

>NZ_CP020002.1|WP_000218968.1|5239541_5239907_-|arsenate-reductase-family-protein
MTVTFYSYPKCGTCQKAKKWFEANDVAYEMIHIVENPPSKEDLRNLHEKSELPLKKFFNTSGMRYRELGLKDKLKDASEDEMYELLASDGMLIKRPIVTDGTNVTLGFNEEQFESVWKKYQ
>NZ_CP020002.1|WP_000026896.1|5239116_5239500_-|glycine-cleavage-system-protein-GcvH
MSIPNNLRYSEEHEWVKTEGNEVVIGITHFAQGELGDIVFVELPEVGATIEADEPFGSVESVKTVSELYAPVSGKVVAVNEELSDQPELVNESPYEGAWMVKVELSDASQVEKLLTAEKYAEMTNQD
>NZ_CP020002.1|WP_000640870.1|5238041_5238386_-|hypothetical-protein
MIYVEKVIIVEGTSDRRKIESIIREPVEIVCTNGTIGLSKMDELVDQFFDKEVYVLVDADDAGEKLRKQFRKEFPQAEHIYIDRSYREVATAPSTHLANVLWGADIDVYTEYLR
>NZ_CP020002.1|WP_000568179.1|5237729_5238029_-|thioredoxin-family-protein
MIDWTGAEATSLIENEEKTVLYVYTPMCGTCQLAKKMLTVVEMTIEELKIGMLDLNYAPHLAKEYGIESVPCLLVFENGTLMKKIYAFHSVEYLYTELK
>NZ_CP020002.1|WP_001242143.1|5237232_5237577_-|hypothetical-protein
MRLYSLLQSFVNYANGQYHLEPLLRREEKTVNFRLGDESCSLQISRDYIELVHEERGTEQIICLDEKDIEQLVNGNVRLQMLMNDGRVQYSGTYRTMLLVESMFHICKPMSVGA
>NZ_CP020002.1|WP_017763726.1|5235793_5236819_-|methionine-ABC-transporter-ATP-binding-protein
MILLENVKKIYKAKSGDVTAVDNANLKIEKGEIFGVIGYSGAGKSSLIRLFNQLEKPTSGQITIANRVISKITGSELRKARQEIGMIFQHFNLLWSRTVRENIEFPLEIAGVDKAKRRKRVDELIHLVGLEGRGDAYPSQLSGGQKQRVGIARALANNPQVLLCDEATSALDPETTDQILDLLLDINKRLGLTIVLITHEMHVIRKICNRVAVMERGKIVETGPVLDVFRNPKQDITKRFVQQLTDSEDTNETIESLIEKYPDGKVIRLQFIGEAVERPVLQRLMQRSDIEVSILQGNIAQTNNGSYGSLVVHLNGEETAIQQAIEGIHQDQVELEVIAHG
>NZ_CP020002.1|WP_000359401.1|5235135_5235801_-|ABC-transporter-permease
MDKLLANVDWNQMLEATGETLYMTAIAALATFVLGLILGLLLFMTAKDNLWENKSINTVIGAFVNIFRSIPFIILIILLIPFTKILLGTILGASAALPALIIGAAPFYARMVEIALREIDKGVIEASKAMGAKTSTIILKVLIPESLPALVSGITVTTIALVGYTAMAGVVGAGGLGTLAYLEGFQRGNNDVTIVATICVLLVVFLIQWIGDSLTTRIDKR
>NZ_CP020002.1|WP_000735090.1|5234299_5235112_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLLLTALISTSIFGLAACGGKDKDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDLDANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSLKELPDGATIIMSNSVADHGRGLAILQKEGILKVKDGVDPVKATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIEGNDSPYANIVAVRKGDKDKKEIKALVEVLHSKEIEDFINKEYKGAVVPVKE
>NZ_CP020002.1|WP_079246114.1|5233421_5234228_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MRKILLSVVTALSVFTLAACGGKEENKLVVGASNVPHAVILEKAQPILEKKGIKLEIKKFQDYVLPNKALADKEIDANYFQHIPYLDKEIQEKGYKIVNAGKIHLEPMGIYSKKYKSLKELPDGGTVIMSNNVAERGRMLALLQKGGVIKLKDGVDVVKATVKDVVENPKNLKFKTDVEPGLSPKLYENNEGDALFINSNYAIDAKLNPTKDAIAIEGSDSPYANIIAVRKGDEKKKEIKELVEVLYSKEIQDFINKEYKGAVLPISE
>NZ_CP020002.1|WP_000929162.1|5232397_5233183_-|Fe-S-cluster-assembly-ATPase-SufC
MAGSTLTVKDLHVSIDGKEILKGVNLEVKGGEIHAIMGPNGTGKSTLSSAIMGHPKYEVTEGSIIIDGEDVLEMEVDERAQAGLFLAMQYPSEISGVTNADFLRSAINARREEGDEISLMKFIRTLDKNMEFLEMDPEMAQRYLNEGFSGGEKKRNEILQLMMIEPKIAILDEIDSGLDIDALKVVSKGINQMRGEEFGCLMITHYQRLLNYITPDFVHVMMNGRIVKSGGPELAQRLEAEGYDWIKKELGIEDETAEQEA
>NZ_CP020002.1|WP_000826875.1|5240318_5240846_-|hypothetical-protein
MKRLSYFLFFILICLVGAGCAKDKEGEKLEYNGRALVIGVVGEKPKDTFRNVKFEEMKLEALEKKSKEVDGFLIMKDHFQEASTEQYKNVFSSLKKPVFFIGLQDKLYSIFITKGIEYNSARKDVNAMYTQGFANIGSGEGQQWAIGLSNGGNTEESIHNMYIVVFQTIADYLNR
>NZ_CP020002.1|WP_000713769.1|5240990_5241638_+|phosphatase-PAP2-family-protein
MKKFKLSSFLPLSYILLLVLVSPLYDVLNKSTVHAVDVTTVVDDWIPFVKAFIIPYLLWFPYLYGALIYYCFADRKQYYVTLSSVIFGKLACFSIYYFWQTTVPRPTVVGTDVFSELVRYIYSIDQPVNCFPSIHVLTTFVIMLAAFKRREQHAFEYYILTFFGTLIILSTLFTKQHAFLDAVSGMTLASILYFGVQLLLAKEPIKVPVKQNHKM
>NZ_CP020002.1|WP_000666176.1|5241697_5242711_-|PTS-sugar-transporter-subunit-IIC
MKEYIMSRVFKASAGIAQGIFVSLGIGLLIENIGRIVDIPLLITIGVVAKSLMAPAIGAGIAFMLGANGLVIFSAMVAGAIGAGSISITEAGLIIKTGEPIGALLTATLAVYIGKRLSGKTALDMMLVPFAAILGSGLVGIWLSHNITPVLNTVGAFIKDSSAGSPFIASIVIAVVWGLLLISPASSAALAIALSLDGVAGGAALAGCVAQFIGFSVISAKENNLGGILAQALCTPKVQLPNITKNPMILVPTVVASAIVGPVSALIFQLEAGKEIAGLGLSSLIAPINLISSEGWEVVPAMVITYIIIPVAVSYILYIALKKAGRIHSGDMTVPQS
>NZ_CP020002.1|WP_106081637.1|5242733_5243903_-|L-lactate-dehydrogenase
MRSFYFLYVNKYIINIFPVVTNMTKMEYNNSQKGQKLCSIFHKVSMVSIVGTSIIKNVKNKRNRLYDQLGEIAMKRHTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYEVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGGKPILQILEEQKERFGEIDLDEIVEKTAKAGWEIYKRKGTTYYGIGNSLAYIASSIFNDDHRVIAVSAILDGEYGEYDICTGVPAIITRDGIREVVELNLTEDEESRFAKSNDILRDYMKTIGY
>NZ_CP020002.1|WP_001002987.1|5243929_5244178_-|spore-coat-protein
MNEKDMVNDYLAGLNASLTSYANYIAQSDNEQLHQTLIQIRNQDEMRQRNMYEYAKQKSYYKPAAPANPMIVQQLKSQLSAE
>NZ_CP020002.1|WP_001180555.1|5244191_5244377_-|hypothetical-protein
MQNLTELEVENLRHLIGGHATIINKLEQYAQTCTDPQLKQMLQKDAQDARNTKQQLMTFLG
>NZ_CP020002.1|WP_001232991.1|5244520_5245234_-|CPBP-family-intramembrane-metalloprotease
MRKTVLDAYNAEREVDNITYKNLVVTIASILGFSLLGGLFLALALGIFGEEVLRANLEGYYLLLFDAAVVTIVLFAYKPVLHFIKNIWDVSILKNGKTYLYLLIGFIIIALTQYVMLELFSFESAEQQRDQLGSLGLQNSLQSIIYVLSVAIITPIKEEILYRGILYRFFEKKYSFLVGIIISSFIFGILHGGFPVTAMIMGIVFAMLYKKTQSILPSIILHIVWNLLVSISMIVSL
>NZ_CP020002.1|WP_016099154.1|5245699_5246248_-|TetR/AcrR-family-transcriptional-regulator
MSPRIGLTLQKIVETAAEIADTNGIQEVTLASLAQRLGIRSPSLYNHVKGLQDVRKNLGIYGIQQLHNKLEEAAEDKQMDEAIHALGEAYVAFVRKHPGLYEATFLRDEEVRKAGDGIVKLCLQVLQQYGLEGENALHATRGFRSICHGFASIEQQGGFGLPLDLDISLHVLLETFIKGLRE
>NZ_CP020002.1|WP_001242581.1|5246251_5246974_-|MBL-fold-metallo-hydrolase
MRMMHEKTVYQLSFLPRAFPVNCYFVEEEDGLTLIDAALPYSAKGILQAAEKIGKPITNIVLTHAHDDHIGALDALKEVLPHVPVYISKRDAKLLEGDTTLQKDEPNTPIKGGVPKKIKTVPDVLLEDGDRVGSLLAIMTPGHTPGSMSFLDVRNKALIVGDAFQTRGGMAVSGQMKFWFPFPAMATWSKEISLQSAQKLSEYEPSLLAAGHGKMIKDPGAVIELAIQEAKRNIESKKEG
>NZ_CP020002.1|WP_002008874.1|5247112_5248915_-|acyl-CoA-dehydrogenase
MKEEIFMEKTVGNAVKGGSFLVDEITIDQVFTPEDFSSEHKMIAKTTEDFIVNEVLPELEYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGGIGLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFIVYAKIDGEHFSAFIVEKEYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRKAMKGELPLLQKAQKLQEELMMMMPEEVGDEPLALQKYLVTNAKKIGLMVAGLAAQKYGKALDKEQEILVNIADIVSNLYAMESAVLRTEKAIKTTGLEKNKQKVLYTEVFCQEAFNEIEADAKETLIAVENGDMLRMMLSSLRKLTRHTPLNVIPKKREIAAKILEDERYTV

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Crispr_ID: NZ_CP020002_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020002_3

5569508-5569641

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP020002_3

>merge|NZ_CP020002|3|5569508-5569641|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGGTTCTTCTTTTTTGTCACTAGTTGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTGTCTTCTGTTTTATTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP020002|3|3|5569508-5569641|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGG	TTCTTCTTTTTTGTCACTAGTTGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTGTCTTCTGTTTTATTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020002.1\|WP_000367477.1\|5577133_5578654_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP020002.1\|WP_003272396.1\|5575938_5576649_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP020002.1\|WP_063676189.1\|5573366_5574386_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP020002.1\|WP_000170825.1\|5571236_5572079_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP020002.1\|WP_079246344.1\|5562982_5563750_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP020002.1\|WP_079246204.1\|5561853_5562735_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP020002.1\|WP_001185961.1\|5572260_5573268_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP020002.1\|WP_000457978.1\|5567442_5568444_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP020002.1\|WP_000057889.1\|5576694_5576931_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP020002.1\|WP_000411275.1\|5574594_5575899_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP020002.1\|WP_000008903.1\|5569185_5569320_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020002.1\|WP_079246208.1\|5578655_5580158_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP020002.1\|WP_000144420.1\|5570529_5571237_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP020002.1\|WP_000931959.1\|5566578_5567013_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP020002.1\|WP_000544012.1\|5568604_5568877_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP020002.1\|WP_079246205.1\|5563862_5564564_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP020002.1\|WP_044783402.1\|5580154_5582017_-\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
NZ_CP020002.1\|WP_000467945.1\|5565559_5566237_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP020002.1\|WP_079246203.1\|5559981_5561793_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP020002.1\|WP_079246206.1\|5564553_5565297_-\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453

Protein	Function_ID	Function_description	E-value
NZ_CP020002.1\|WP_000367477.1\|5577133_5578654_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	1.04015e-150
NZ_CP020002.1\|WP_003272396.1\|5575938_5576649_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	1.11897e-33
NZ_CP020002.1\|WP_063676189.1\|5573366_5574386_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	2.83575e-135
NZ_CP020002.1\|WP_000170825.1\|5571236_5572079_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.57597e-89
NZ_CP020002.1\|WP_079246344.1\|5562982_5563750_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.44507e-105
NZ_CP020002.1\|WP_079246204.1\|5561853_5562735_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP020002.1\|WP_001185961.1\|5572260_5573268_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.03533e-30
NZ_CP020002.1\|WP_000457978.1\|5567442_5568444_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP020002.1\|WP_000057889.1\|5576694_5576931_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	1.23409e-23
NZ_CP020002.1\|WP_000411275.1\|5574594_5575899_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP020002.1\|WP_079246208.1\|5578655_5580158_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	1.30473e-175
NZ_CP020002.1\|WP_000144420.1\|5570529_5571237_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	3.22291e-09
NZ_CP020002.1\|WP_000931959.1\|5566578_5567013_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP020002.1\|WP_000544012.1\|5568604_5568877_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP020002.1\|WP_079246205.1\|5563862_5564564_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.27825e-83
NZ_CP020002.1\|WP_044783402.1\|5580154_5582017_-\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP020002.1\|WP_079246206.1\|5564553_5565297_-\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	1.29519e-83
NZ_CP020002.1\|WP_079246203.1\|5559981_5561793_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP020002.1\|WP_000467945.1\|5565559_5566237_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	5.32085e-82

>NZ_CP020002.1|WP_000008903.1|5569185_5569320_-|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEELEREE
>NZ_CP020002.1|WP_000544012.1|5568604_5568877_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP020002.1|WP_000457978.1|5567442_5568444_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP020002.1|WP_000931959.1|5566578_5567013_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP020002.1|WP_000467945.1|5565559_5566237_-|CpsD/CapB-family-tyrosine-protein-kinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHVRSIIVTSADPGDGKTTTIANLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKLLGVVLNDKREEKEQYGYY
>NZ_CP020002.1|WP_079246206.1|5564553_5565297_-|capsular-biosynthesis-protein
MEETISLKELFHILKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGAMFQAGEIQTNIQLTNTYKVIIKSPVILEQVNEKLNLNMTSQALTGKINVANEKDSQVISVTAEDKDPKLARDIANATADVFKGEVAKIMNVDNVTVLSKAEVAENQSPIKPAPMLNVAIAFIVGLIASVGLAFLLEYLDNTVKKEEDVENLLGLPVLGIVARMDEETMNVKSHAPSSRKVRGQTIGS
>NZ_CP020002.1|WP_079246205.1|5563862_5564564_-|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAIDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTHSERLEKCVQTTSVDNLHFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASILVVRSESTEKETAVKAKGLLESAKGKLLGVVLNDRKREEGLYYYYGAN
>NZ_CP020002.1|WP_079246344.1|5562982_5563750_-|tyrosine-protein-phosphatase
MIDLHCHILPGIDDGAQTVTDSLAMAQQAVSEGIHTIVATPHHQNGKYVNERTSIIHHIKQLNDELQQHNIPLTILPGQEVRLYGDLLEDYEAGKIVTLNETNKYIFIEFPSNHVPRYTEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNIVNKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMIASDAHNTTSRGFHLAESYELIEKEFGMSVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP020002.1|WP_079246204.1|5561853_5562735_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQSLLEKGKHEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPIEQSDRRYQVRQFVEKPVQGTAPSNLAIMGRYVLTPEIFMFLENQQTGAGGEIQLTDAIQRLNEVQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQNEELNVELMKYMKELVKKEEVHS
>NZ_CP020002.1|WP_079246203.1|5559981_5561793_-|polysaccharide-biosynthesis-protein
MSYRRRLSLLILLDSFIVLTAVYLSYWFIHPNVLNKIPMTVVISSITLLCSHHVFAAIYKLYNKAWEYASIGELKQIFKAITLSILVTAIVQQIINHDIYVRILAIAWMLHLLLIGGSRFVWRMFRDTYITKATNKKRTLIIGAGSAGTMVVRQLQHNKEADLYPIAFVDDDRNKQKLEIYNVPVVGTTNHIQEIVEDNDIEHIIIAIPSLNRSQINEIFEKCRKTKAKTQIVPMLEDLLDGKLSVNEFRDVQVEDLLGREPIKLDDAGIGEKITGKTILVTGAGGSIGSEICRQVMKYKPAKIVLLGHGENSIYNIEMEMRVTYKDSVEITTEIADIQDRHKIFEIMKKHQPYIVYHAAAHKHVPLMERNPEEAVKNNIFGTKNVAEAADTFKVNTFVMVSTDKAVNPTNVMGATKRFAEMIVQHMASVSTSTRFVAVRFGNVLGSRGSVIPLFKKQIQKGGPVTVTHPDMIRYFMTIPEASRLVIQAGTLARGGELFVLDMGDPVKIVDLAKNLITLSGYSIEEIGIEFTGLRPGEKMYEELLNEGEIHPEQIFPKIHIGKAVLIDQGILRQFMNDFEGISKEEIRERLLDIANNKVNLKN
>NZ_CP020002.1|WP_000144420.1|5570529_5571237_-|ABC-transporter-permease
MTFSMKRFSAIVRKEINDAGKNSQVILMALLPILLAVFYSNMDSIKEFFAGFVIVMTITMVGSYVQAIIIAEEKEKHTLRVLMLSPASPIEVILGKSVLTVFFVLASSFISLVILDTFKGNIGMLVIIILIGTLLCVVLGTIVGLLSQNIAQTSILGLPIFIIFIMGPMLQEMVKNEFIIKVVNLLPTNHVMEALQKVIKGEGFIAIQEHILNNTIWTICLIILCIIVYKKKQLD
>NZ_CP020002.1|WP_000170825.1|5571236_5572079_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFDGKTALQNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLAQVNLLDDKKTPVKKLSKGMKQRVILARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNEEGTTIFLTTHNMDEAETLCNRIAFLCGGEIVALDTPENLRLQYAKDQIEVVLKDKQKEVVQKDELGAKRISEWMKKGELLSIHSYEPTLGDIFIEVTGRGL
>NZ_CP020002.1|WP_001185961.1|5572260_5573268_-|ATP-binding-cassette-domain-containing-protein
MALLELKQLGKTNQLPEIELKVEKGQCIVLQCNNHTAKVLHRIIIGEEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAYNRLKVKEYFNFLIGLYESKISIEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRIMIHNPDLVILEEPEQNVDIESTIIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEVEEVGEEKVIQMIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLGELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP020002.1|WP_063676189.1|5573366_5574386_-|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVESLPMEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGGKKNNADVTDTVKDQVYKSKEELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTNEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIITTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVEIKTMNDYEGKLMVKK
>NZ_CP020002.1|WP_000411275.1|5574594_5575899_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP020002.1|WP_003272396.1|5575938_5576649_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVLFLVGYREMKPISDEQKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKDKANIQKWEVEQSPDGYKATSYKKFASHEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQKVNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP020002.1|WP_000057889.1|5576694_5576931_-|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMKSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP020002.1|WP_000367477.1|5577133_5578654_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCIAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKNRASNEAAMKYVISGGIGTAITLFGMSYLYGITGSTNIVDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGATTPVTAFLGTISKIAGFLLIIRLFLMVFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNIKRLFAYSGIAHAGYLLVPLVALSPFTLDSMWFYMLAYMLMNIGAFAIIHGLILQNDKENITIFTGLYKKSPFAAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP020002.1|WP_079246208.1|5578655_5580158_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAIVLACTYASGKSLSLFDEKVKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLAMLAAIAAFSIKSNLKAFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIVELKEILRSVSAGGELVIPSSLQLGVFIAIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDVATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLASLNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSDITVLGGLAKSVPILSGFFLAGGMASLGSPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK
>NZ_CP020002.1|WP_044783402.1|5580154_5582017_-|NADH-quinone-oxidoreductase-subunit-L
MIDYAWLIPLFPLVSFLLLIIFGKKIREGSSVLSIFFVFLSFILAVLVLIERFSEASVKHKWVWLRAGDVDISFGFEVTALGALMLFIVTLVSLLVHVYSKGYMKGDERLPTFYAYLGLFTFAMLGLVISTNLLQLYIFWELVGLGSFLLIGFYFFKEEAKAAAKKAFIMTRIGDVGLFIGMILIFWYAGSFEYDAIFRAIYTGDLPPYMITITAILIFIGAMGKSGQFPLHTWLPDAMEGPTPVSALIHAATMVAAGVYLVATMFPLFSASAVAMQTVAIVGAFTAIFAASIGLVQTDIKRVLAYSTVSQLGYMMLALGSAGYVAGIFHLTTHAFFKALLFLAAGSVIHAVHTQNINKMGGLQKKMKVTGTLFLIGTLAISGVPLLSGFFSKDEILAATWMNGNYFLFVLAVLAAFLTAFYMFRLYFLVFIGEAKTKEDVHESPRIMTYPMIVLGVLAVVAGYINTPWFGTFLGDWLTKDVGFKVEEAHGPVWIMIVATLVSFAGIALAYSIYGKKSISREWAGGTGTSLYNLLKEKYYVDELYNMTVIPITKGIARVLRLFEVYVVEGIAVLIASVVKGTSNLGSKLQNGNVQVYGTVTAVSLAVLVIILLYTGGDLR

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Crispr_ID: NZ_CP020002_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020002_4

5657369-5657476

Orphan

Consensus_repeat	Method
CCGCTTCCGCTTTTCTTTATTGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020002_4

>merge|NZ_CP020002|4|5657369-5657476|CRISPRCasFinder
CCGCTTCCGCTTTTCTTTATTGTCTAGCTCCAGCGGCTAGAATACTCGGTGGCTTCGCGCCTTCCTCCTCCTATTCTGAACGAGCCGCTTCCGCTTTTCTTTATGTCC

>NZ_CP020002|4|4|5657369-5657476|CRISPRCasFinder
CCGCTTCCGCTTTTCTTTATTGTC	TAGCTCCAGCGGCTAGAATACTCGGTGGCTTCGCGCCTTCCTCCTCCTATTCTGAACGAG
CCGCTTCCGCTTTTCTTTATGTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020002.1\|WP_000738257.1\|5656335_5656710_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020002.1\|WP_001202431.1\|5641372_5642107_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP020002.1\|WP_000045708.1\|5654788_5656189_+\|M28-family-peptidase	unknown	unknown	gnl\|CDD\|349911
NZ_CP020002.1\|WP_000619243.1\|5639642_5640245_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP020002.1\|WP_001086463.1\|5657593_5659264_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP020002.1\|WP_000613237.1\|5659903_5660890_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132883
NZ_CP020002.1\|WP_002083543.1\|5643163_5643958_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|237252
NZ_CP020002.1\|WP_000779933.1\|5660915_5661278_-\|YxeA-family-protein	unknown	unknown	gnl\|CDD\|227613
NZ_CP020002.1\|WP_063676207.1\|5642103_5643006_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP020002.1\|WP_145953846.1\|5644726_5654299_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|227268
NZ_CP020002.1\|WP_000042780.1\|5666614_5667340_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176506
NZ_CP020002.1\|WP_000444236.1\|5664885_5666049_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341027
NZ_CP020002.1\|WP_000996325.1\|5661512_5662550_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|379113
NZ_CP020002.1\|WP_000570631.1\|5640241_5641372_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP020002.1\|WP_000424696.1\|5663893_5664721_-\|spermidine-synthase	unknown	unknown	gnl\|CDD\|234843
NZ_CP020002.1\|WP_001147494.1\|5636824_5637682_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376189
NZ_CP020002.1\|WP_001209831.1\|5662801_5663674_-\|agmatinase	unknown	unknown	gnl\|CDD\|273514
NZ_CP020002.1\|WP_000734733.1\|5636589_5636736_-\|quorum-sensing-peptide-PapR	unknown	unknown	gnl\|CDD\|368687
NZ_CP020002.1\|WP_000276560.1\|5666054_5666462_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133401
NZ_CP020002.1\|WP_079246217.1\|5659263_5659701_-\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378129

Protein	Function_ID	Function_description	E-value
NZ_CP020002.1\|WP_001202431.1\|5641372_5642107_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.44564e-11
NZ_CP020002.1\|WP_000045708.1\|5654788_5656189_+\|M28-family-peptidase	gnl\|CDD\|349911	cd05661, M28_like_PA, M28 Zn-peptidase containing a PA domain insert. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. This subfamily is composed of uncharacterized proteins containing a protease-associated (PA) domain insert which may participate in substrate binding and/or promote conformational changes, influencing the stability and accessibility of the site to substrate.	2.43367e-114
NZ_CP020002.1\|WP_000619243.1\|5639642_5640245_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.30273e-68
NZ_CP020002.1\|WP_001086463.1\|5657593_5659264_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP020002.1\|WP_000613237.1\|5659903_5660890_+\|LD-carboxypeptidase	gnl\|CDD\|132883	cd07062, Peptidase_S66_mccF_like, Microcin C7 self-immunity protein determines resistance to exogenous microcin C7. Microcin C7 self-immunity protein (mccF): MccF, a homolog of the LD-carboxypeptidase family, mediates resistance against exogenously added microcin C7 (MccC7), a ribosomally-encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. The plasmid-encoded mccF gene is transcribed in the opposite direction to the other five genes (mccA-E) and is required for the full expression of immunity but not for production. The catalytic triad residues (Ser, His, Glu) of LD-carboxypeptidase are also conserved in MccF, strongly suggesting that MccF shares the hydrolytic activity with LD-carboxypeptidases. Substrates of MccF have not been deduced, but could likely be microcin C7 precursors. The possible role of MccF is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	3.83787e-123
NZ_CP020002.1\|WP_002083543.1\|5643163_5643958_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|237252	PRK12896, PRK12896, methionine aminopeptidase; Reviewed.	1.27721e-146
NZ_CP020002.1\|WP_000779933.1\|5660915_5661278_-\|YxeA-family-protein	gnl\|CDD\|227613	COG5294, COG5294, Uncharacterized protein conserved in bacteria [Function unknown].	5.70177e-11
NZ_CP020002.1\|WP_079246217.1\|5659263_5659701_-\|DUF1934-domain-containing-protein	gnl\|CDD\|378129	pfam09148, DUF1934, Domain of unknown function (DUF1934). Members of this family are found in a set of hypothetical bacterial proteins. Their precise function has not, as yet, been defined.	8.17804e-28
NZ_CP020002.1\|WP_145953846.1\|5644726_5654299_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|227268	COG4932, COG4932, Predicted outer membrane protein [Cell envelope biogenesis, outer membrane].	0
NZ_CP020002.1\|WP_000042780.1\|5666614_5667340_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176506	cd08563, GDPD_TtGDE_like, Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in Thermoanaerobacter tengcongensis glycerophosphodiester phosphodiesterase (TtGDE, EC 3.1.4.46) and its uncharacterized homologs. Members in this family show high sequence similarity to Escherichia coli GP-GDE, which catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. Despite the fact that most of GDPD family members exist as the monomer, TtGDE can function as a dimeric unit. Its catalytic mechanism is based on the general base-acid catalysis, which is similar to that of phosphoinositide-specific phospholipases C (PI-PLCs, EC 3.1.4.11). A divalent metal cation is required for the enzyme activity of TtGDE.	3.74417e-123
NZ_CP020002.1\|WP_000444236.1\|5664885_5666049_-\|MFS-transporter	gnl\|CDD\|341027	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis multidrug efflux protein YfmO, bacillibactin exporter YmfD/YmfE, uncharacterized MFS-type transporter YvmA, and similar proteins. YfmO acts to efflux copper or a copper complex, and could contribute to copper resistance. YmfD/YmfE is involved in secretion of bacillibactin. The YfmO-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.79287e-98
NZ_CP020002.1\|WP_000996325.1\|5661512_5662550_+\|transcriptional-regulator	gnl\|CDD\|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	5.69859e-53
NZ_CP020002.1\|WP_000570631.1\|5640241_5641372_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.69283e-58
NZ_CP020002.1\|WP_000424696.1\|5663893_5664721_-\|spermidine-synthase	gnl\|CDD\|234843	PRK00811, PRK00811, polyamine aminopropyltransferase.	2.2788e-169
NZ_CP020002.1\|WP_001147494.1\|5636824_5637682_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376189	pfam18768, HTH_Bact, Helix-turn-helix bacterial domain. The bacterial PIcR helix-turn-helix transcription factor includes five TPR units of different lengths. This entry represents the central, medium-sized HTHs repeat.	7.4378e-19
NZ_CP020002.1\|WP_001209831.1\|5662801_5663674_-\|agmatinase	gnl\|CDD\|273514	TIGR01230, Agmatinase_Agmatine_ureohydrolase_AUH., agmatinase. Members of this family include known and predicted examples of agmatinase (agmatine ureohydrolase). The seed includes members of archaea, for which no definitive agmatinase sequence has yet been made available. However, archaeal sequences are phylogenetically close to the experimentally verified B. subtilis sequence. One species of Halobacterium has been demonstrated in vitro to produce agmatine from arginine, but no putrescine from ornithine, suggesting that arginine decarboxylase and agmatinase, rather than arginase and ornithine decarboxylase, lead from Arg to polyamine biosynthesis. Note: a history of early misannotation of members of this family is detailed in PUBMED:10931887.	1.75128e-134
NZ_CP020002.1\|WP_000734733.1\|5636589_5636736_-\|quorum-sensing-peptide-PapR	gnl\|CDD\|368687	pfam05968, Bacillus_PapR, Bacillus PapR protein. This family consists of the Bacillus species specific PapR protein. The papR gene belongs to the PlcR regulon and is located 70 bp downstream from plcR. It encodes a 48-amino-acid peptide. Disruption of the papR gene abolishes expression of the PlcR regulon, resulting in a large decrease in haemolysis and virulence in insect larvae. A processed form of PapR activates the PlcR regulon by allowing PlcR to bind to its DNA target. This activating mechanism is strain specific.	1.80359e-05
NZ_CP020002.1\|WP_000276560.1\|5666054_5666462_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133401	cd04774, HTH_YfmP, Helix-Turn-Helix DNA binding domain of the YfmP transcription regulator. Helix-turn-helix (HTH) transcription regulator, YfmP, and related proteins; N-terminal domain. YfmP regulates the multidrug efflux protein, YfmO, and indirectly regulates the expression of the Bacillus subtilis copZA operon encoding a metallochaperone, CopZ, and a CPx-type ATPase efflux protein, CopA. These proteins belong to the MerR superfamily of transcription regulators that promote expression of several stress regulon genes by reconfiguring the spacer between the -35 and -10 promoter elements. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	1.7316e-36
NZ_CP020002.1\|WP_063676207.1\|5642103_5643006_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.63354e-89

>NZ_CP020002.1|WP_000738257.1|5656335_5656710_+|hypothetical-protein
MKKMILVGALTLAGITGATAFIPETKVAAAAQEQSFTKFYSLQTGGSSEQEPIFLQKGQELTIHPNSKTPSYSVYDSNHNLIGRYSDGYGRIFTAKTDGNMYVQFHAPYVYYSPVSFSVTYTIQ
>NZ_CP020002.1|WP_000045708.1|5654788_5656189_+|M28-family-peptidase
MSKSLKQKIVSSLLAISLAVSLAPIGQAKADSTSEVPQTPSITKQIDPNRAIEHVRFLSETIGPRPGGTKSEEWASRYIGMQLKSMGYDVEYQPFQVPDQYVGFIESPLSTKRNWQAGAAPNALISTEAITAPLIFVQGGTKLEDIPNEVNGKIVLFERGTTVTDYNKQVENAVSKGAKGVLLYSLIGGRGNYGQTFNPRLTKKQSIPVFGLAYAQGNAFKEEIAKKETTILSLKARHESKLTSLNVIAKKKPKKSTGNEKAVVVSSHYDSVVGAPGANDNASGTGLVLELARAFQNVETDKEIRFITFGSEETGLLGSDYYVNSLSQKERDRILGVFNADMVATNYDKAKNLYAMTPDGSTNFVTDAALQAGKQLNNDLVLQGKFGSSDHVPFAEAGIPAALFIWMGVDSWNPLIYHIEKVYHTPQDNVLENISPERMKMALDVIGTGVYNSLQKPITQTEQKAA
>NZ_CP020002.1|WP_145953846.1|5644726_5654299_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKKLFNVCLIVFVLFSQLASFPYNQVKAETLTGDSLFDTVEMKDATNHIIDEAKNPNNLIKIGSTIQVEYAWSIKDQQVAHANDTAVVQIPLALKVSKDLQGDLVTDQKNIGQYFITAKDNKLKLIFNDQVENLKDAKGKIKVDTVFNSTLKTGEKSVQIAFPLGTIVQPISVPVQVEDSKEDGTKQDTNKQVQDPVAKPVTDNPEQNPATKPVTDNPEQKPATKPVTDNLEQNPATKPVTDNPEQNPVAKIATGNPEHKLASSPVENTNSGPKQITTNILTGVKLTDKDGKPFTEDNRPSTDSPANIEFTWELLKSMNVKSGDYYIFDLPKHFKIYNTINSPLYDSENNQIGNFTVTKDGKVTMTFNDYVEEHPDVAGNLQLKTEFNKAEIKGTTTQEIPFPIKDKDVSITVDFKPNVQTATNKKGVPDRPINTNEINWKVEMNKTKETLKNAVFKDNIPQGTSLNKDSIKVYYLEVDVNGNVMRGAEAEPTDYNIISSDGSKLEIAFKDSINKAYQIEYATKITDENIKSFRNNVTITSDNQKQQNASSTVTVSRGTHLNKTSKYDPKTQTIEWTITYNGDQREIKKADAILKDIFDDTHELDANSIVVKNASYNEKGTLVTGDAVNNYTVNNKKNGFDLQFNDDINSAYVITYKTKPTNKVIEDGKVKNKVTADNDSSKENEASFKQQNIIKSNNKAETNYKDKTTTWTIIVNNNNYPLNNAIITDTFDHGGLQLKDKKLEIKDGNYTLQAGTDYVLDATDKGFKITLIGTYQSNMTKTLVVKYTTDFDYTKLENGKTSFKNTGNLSWIDTDSKPQSNKVEANFDPDTFTKANGYKYGSYNAQTKEITWIIGFNYNNVEIKDPSVIDVIQDKQKLVPGSIEVRDMILNGNPDNAQPGNAVPTEKYELEEPTEKNKNTLKVHFKQSINSPYYIIFKTSLDGELIQGTYKNEADLKDGSKIVNTLTGDTQVNKGGSFVTKKAVQDDNYINWSIAINESQSTIADAVVTDDPTENQVIVEDSFHLYPTTVDPYGNLTKDKVNELKEGTDYKLKITTDNTTGKQHFEIAFLKKIDRAYILEYRSLINADDKEKVSNKAKITGNKLTVKNTETTETIEVRMSSGSGGGSATKGRGNLEIIKVDNDNKNVLLAGAEFTLYDRTGKTVIRKITTDKDGIAKFNNLKRDKYLLKETKAPEGYVISWDLKQGKIVELGTQETTTYKLANKKFVGKVVLTKSDDLNKNATLQGAIFTLLDKDKKVIPEHKELTTNNNGQIIIDKLKPGTYYLQETKAPEHYQLDSKLIPFTISIDQTTVVNLTATNSLTKGSALLTKVDNYNKTLAGAEFTVQDRNGKNIPGYEKLTTNEHGQIEAKDLRPGKYQFVETKAPEHYELDKTPILFEIEKSQTTVASVTAKNALIKGDITLTKVDDTDGTTLEGAVFKIVNDKNEDVRTNLKTEKDGTLTVKDLDPGDYQFIETTPPKYYDLNKEPIPFTIEKSQTSIISITAKNSLTTGAVELLKVDEFDKKTPLAGAMFKIVNDKNEDVRTELTTDTNGTVKASDLRPGKYKFIETKAPEHYELRSTPIEFTIEKGQKTPIVITAENGLLPGDVELTKLDDTDGTALIGAVFKIVNNKNEDVRTELVTNQEGKIIATGLRPGNYKFIEMKAPEHYALNKTPIEFTIKESQATAINVTATNSLTKGGIELTKVDSVNAKETLEGAVFKIVNDKGEDVRTELTTDKDGKLVVQDLRPGNYKLIETKAPTYYDVNEEPIEFTIEKGQQKLLPLTFKNSLTKGKVKLIKEDDVESAKALAGAVFTLQDATGKEIMKDLITDAHGVLVIPDLAPGDYQFIEVKAPEHYKLDQTPIKFAIKKGSKEDLPIPVTVKNSLLTGGVTLTKVDDVDGTTLEGAEFIIVDAHDTKKVIRKGLTTDKNGKITASDLRPGDYQFVEVKAPKDYTLSKEPIPFTIEKSQKENITVTATNSLKKGAVTLTKIDDIDRTMLEGAIFKIVDMNGKEVHTNLVTDKNGKISVSDLRPGDYQFIETKAPEHYVLEETQIPFTIERSQTKEINVTGKNALKKGSVELTKIDDIDINTKLANAVFNLLDADGELVEEGLKTNDEGKIVVENLRPGTYQFVETIAPEHYVLDKKPIVFTIKKSQTEALHVTATNALTKGAVKLSKVDDVDATVLKDAVFKIVNMNGDVVHKDLVTNEQGLIEINDLRPGDYQFIETKAPKDYVLDETPIKFTIEKGQKKSISLTATNSLKQGSIELLKVDDLNDQTKLADAVFNLLDQNGKVLKTDLKTNSEGKIVVENLRPGTYQFVETTAPEHYDLDKKPIIFTIEKSQKDIATVTMKNSLTKGGVELSKVDDVDGTTLEGAVFKIADMNGTVIRKDLVTNQQGKISVSDLRPGDYQFIETTAPKHYNLNKEPIPFTITQSQAEPVSVTATNSLTKGTVELSKVDDVDGTALKDAIFKITDLNGNDIRTELTTDVHGKISVSDLRPGDYQFVETKAPEHYKLDSTPIKFTIKKSQKEKLQVTTTNSLTEGAVELIKVDDINPDTKLSDAVFNIIDAKGKIVRTDLTTDKDGKITATNLRPGDYQFIEMKAPKHYDLNKTPISFTIEKSQLTHASVTAKNGLTKGGVELTKVDSIDKKEMLEGAVFKITDLNGNDIRTNLVTNKDGKIIAKDLQPGDYEFIETKAPKHYDLNEEPIKFTIERSQTKHVFVTAINSLTKGSVELIKVDDAKQNTTLEGAVFKIVNKDGHDVRTDLTTDKNGRLVVDELPPGDYEFIETKAPEHYDLNKTPIKFTVKKGQEKIASVTATNSLTKGAVELTKVDDIDGTTLEGAIFKIVDMDGKDVRSDLATDKDGKISVSDLRPGDYQFIEMKAPKHYDLNQNPIKFTVEKSQTAKTSVTATNSLTKGAVELTKVDDIDGTILEGAIFKIVDMDGKDVRSDLTTDKDGKISVSDLRPGDYQFIEMKAPTGYDLNVKPIPFTITKGQTQVTSVTALNSLTTGSIELTKVDIDHHGTLEGAIFNILDQDGNVIREGLKTDQQGKVIINDLKPGNYQLVETKAPKGYQLDASPIKFTIDKAQATPLQITVSNKKIESSSGGDDKPVTPPNKEENKGTETSEKHENGTSEETSNETDNKQQDDRNTDKHLPNTGHKEDPTQTVGIVLLLAGLLSILAKKRKKNY
>NZ_CP020002.1|WP_002083543.1|5643163_5643958_+|type-I-methionyl-aminopeptidase
MIQSDKIYIRGRTVVFMIIRNEQDLEGLRKIGRIVALAREEMKKQAKPGMTTKELDLIGKKVLDEHGAISAPEKEYDFPGVTCISVNEEVAHGIPGDRVLKEGDLVNVDVSAALDGYYADTGISFVLGEDEAKEKLCQAAVDAFWAAMKKVKAGSKQNQIGRAVSNFAHKSGYNVIQNLTGHGIGLSLHEAPNHILSYYDPMDNTLLKDGLVIAVEPFISMKADHIIERGDDGWTFITPDKSLVAQCEHTVVVTRGEPIILTEI
>NZ_CP020002.1|WP_063676207.1|5642103_5643006_-|ABC-transporter-ATP-binding-protein
MEKIIEVNGVSKTFKHKNAVNNVSFHVDKGEIVALLGPNGAGKTTIISMMLGLKDPTEGTVSIFGKSPKQRGVRNNLGAMLQEVSVIDSITVEEAIELFRSYYKNPVAKETLLQLSNLESERKQRCEKLSGGQKRRLNFALALAGNPDLLFLDEPTVGMDITSRRTFWETIRKLASEGKTIILTTHYLEEADALANRILLFANGKIIADGTPDEMKATISRKTITFYSKESIPTKLLKELPNVTEVKSNEGRFILTTEDTDATLKAIYQRNLPVIDVSVERGSLDEAFEQFVANQKEEIA
>NZ_CP020002.1|WP_001202431.1|5641372_5642107_-|ABC-transporter-permease
MRALWMQCKIEILRTFRNKLFIFFSLLMPVMFYYIFTNVVQVPQNGDAWKAHYLISMATFSIVGTALFSFGVRLSQERGQGWTHLLKITPLPEGAYLTAKIIAQTVVNAFSILVIFIAGILINHVELTVGQWIGAGLWLLLGVTPFLALGTVIGSIKKADAAAGLANILNMSLAIVGGLWMPIEVFPKILRTIGEWTPTYHFGSGAWDIVAGKSIGWENIAVLGGYFLIFVVVSIYIRKRQEAV
>NZ_CP020002.1|WP_000570631.1|5640241_5641372_-|sensor-histidine-kinase
MIEKKRIEVFPKHMGFFPYMWFVYLLFPIYHLAQASGWKLVIGSGMLIIFIVTYRQLYFVQRTFVFWACIQMVLIFLFALFYNPFMIFFGFFTASAMGFAPNKKVFRVLLCSLVIMLGAFLFVNMNQLTTTSLVNIVPMFILMLLTPFGMRNFNQKKMLKNQLNEANEQIKDLVKREERQRIARDLHDTLGHTLSLITLKSQLVEKLIVKNPERASVEAKEITQTSRTALKQLRELISDMRMITVEEELEQIKAILQAANIELEVRQEASSSSLSPIEQNIVGMCLREAVTNVVKHSKAKRCAVSVLESQGELILKVEDNGIGLTDQNHDGNGIRGMKERIALIDGFVELGTINPGTLLTVKVPVVIRTGKDEVRA
>NZ_CP020002.1|WP_000619243.1|5639642_5640245_-|response-regulator-transcription-factor
MIRIIIAEDQRMLRGALGALLDLEDDIEVIGQAANGEEALKLIESLKPDISIMDIEMPIQSGLDVAEALKKEKSPCKVMILTTFARPGYFERAMKAGVHGYLLKDSPSEDLAAAIRNVMKGKREVSQELMFGLWQEQNPLSDREKEVLLLAKEGKTANEIAKALYLSPGTVRNYISEVLTKLDAKNRIEAITIAEEKGWI
>NZ_CP020002.1|WP_001147494.1|5636824_5637682_-|helix-turn-helix-transcriptional-regulator
MQAEKLGSEIKKIRVLRGLTQKQLSENICHQSEVSRIESGAVYPSMDILQGIAAKLQIPIIHFYEVLIYSDIERKKQFKDQVIMLCKQKRYKEIYNKVWNELKKEEYHPEFQQFLQWQYYVAAYVLKKVDYEYCILELKKLLNQQLTGIDVYQNLYIENAIANIYAENGYLKKGIDLFEQILKQLEALHDNEEFDVKVRYNHAKALYLDSRYEESLYQVNKAIEISCRINSMALIGQLYYQRGECLRKLEYEEAEIEDAYKKASFFFDILEMHAYKEALVNKISR
>NZ_CP020002.1|WP_000734733.1|5636589_5636736_-|quorum-sensing-peptide-PapR
MKKLLIGSLLTLAMAWGISLGDTTLEKSQIISHNDQEVQVAADLPFEF
>NZ_CP020002.1|WP_001086463.1|5657593_5659264_-|arginine--tRNA-ligase
MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKKAPRMIAEELVANFDKAKASIEKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETNTGKGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNVLAKAGYDVSREYYINDAGNQIHNLALSVEARYMQALGLDKEMPEDGYHGADIIGIGKRLAEEFGDRYAKADAEESYEFYRSYGLKYELAKLQKDLESFRVKFDVWFSETSLYKNGKIDAALTVLKERDEIFEEGGATWFRSMTYGDDKNRVLIKNDGSYTYLTPDIAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYDKETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEVGVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLAADGDVNYKLVTSEKEVELLKKLGEFPAVVADAAQKRLPHRITSYAFELAAALHSFYNAEKVLNQDNLELSKARYELMKAVRTTLQNALAIVGVSAPEKM
>NZ_CP020002.1|WP_079246217.1|5659263_5659701_-|DUF1934-domain-containing-protein
MKKQLAGLPIHVHFVTEIREGARKETVAFEANGQYYVKGQGTYVTFQEPNEQGEVKTIIKIQDEQVLIMRSGAISMRQTHVKGEWTTGTYTSELGTFALQTKTDNVLFKWSDEKKKGQLFLTYALLLSEQEAGRYTITINLKEAK
>NZ_CP020002.1|WP_000613237.1|5659903_5660890_+|LD-carboxypeptidase
MIPTKLKKGDEIRVISPSCSLSIVSNENRKLAIKRLTDMGFQVTFSKYADEIDRFASSSISSRVQDLHEAFRDPNVKAILTTLGGYNSNGLLKYLDFDLIRENPKFFCGYSDITALNNAIYAKTGLVTYSGPHFSSFGMEKGLHYTADYFLQCLTANEPIEIIPAETWSDDSWYMDQENREFIKNEGYVPIQKGEATGEIIGGNMSTLNLLQGTPYMPNLKGKILFLEEDSLTGKSTLKTFDRYLHSLMQQPNFEHITGIVIGRMQKEAECTIADIQEMIASKPELAHIPIIANASFGHTTPIFTFPIGGRAKIISNKEKTSITILAY
>NZ_CP020002.1|WP_000779933.1|5660915_5661278_-|YxeA-family-protein
MKLVIKVLAVFAIILGGTAYYLNTKTEGVHAFVDNFFSNKEIQDYYAVVDKGEKKDGEYLYTFKGYTEDGNQQIIKRMVNRELHAGAFIKIYAKGMQGKGWAEITKESIPQKALQKIEKP
>NZ_CP020002.1|WP_000996325.1|5661512_5662550_+|transcriptional-regulator
MAILQGLALLLVVLCLFTLFSYRAPYGMKAMGALANAAIASFLIEAFHRYIGGEMFHNDFLQSVGEASGSMSGVAAAILVALAIGVSPVYAVLIGIATSGFGILPGFFAGYVCAFVVKFLEKKLPAGVEFLAILFIAAPISRGMAMLMDPLVNATLGKIGSMISVATTESPIIMGIMLGGLITVISTSPLSSMALTAMLGLTGLPMAIGSLAVAASAPMNFIFFKRLKICSKKDTIAVAIEPLTQADVVSANPIPIYMTNFVGGALAGIITSLFQLVNNAPGTASPIPGLLVLFGFNDVIKVTIAAVLCGIVTTIIGYIGSIVFRKYPIRSADEIRGVNSEEKVA
>NZ_CP020002.1|WP_001209831.1|5662801_5663674_-|agmatinase
MRFDEAYSGKVFIKSHPSFEESKVVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELEEVKYFDAGDIPLPFGNAQRSLDMIEEYVSKLLDADKFPLGLGGEHLVSWPIFKAMAKKYPDLAIIHMDAHTDLRESYEGEPLSHSTPIRKVCDLIGPENVYSFGIRSGMKEEFEWAKEVGMNLYKFDVLEPLKEVLPKLAGRPVYVTIDIDVLDPAHAPGTGTLEAGGITSKELLDSIVAIANSNINVVGADLVEVAPVYDHSDQTPVAASKFVREMLLGWVK
>NZ_CP020002.1|WP_000424696.1|5663893_5664721_-|spermidine-synthase
MELWFTEKQTKHFGITARINRTLHTEQTEFQKLDMVETEEFGNMLILDGMVMTTEKDEFVYHEMVAHVPLFTHPNPENVLVVGGGDGGVIREVLKHPSVKKATLVEIDGKVIEYSKQYLPSIAGALDNERVEVKVGDGFLHIAESENEYDVIMVDSTEPVGPAVNLFTKGFYAGISKALKEDGIFVAQTDNPWFTPELITTVFKDVKEIFPITRLYTANIPTYPSGLWTFTIGSKKHDPLEVSEERFHEIETKYYTKELHNAAFALPKFVGDLIK
>NZ_CP020002.1|WP_000444236.1|5664885_5666049_-|MFS-transporter
MESKQKLGRLITVVATFLAFSGIGVVDPILPIIAEKIGATHWQVEMLFTAYILTMAIMMLPAGIFASRFGDKRMMTIGLAIVTVFAFICGISQTIAQLSLFRAGWGLGNAMFFATAMTLLIALSKEVHEAVGLYEAAIGLGMAGGPLLGGILGGHSWRYPFFATSILIFLAFILVFFFVKEPERKVKRKAAGVGELLNLVKYKPFMQGAISGMLYYYGFFVVLAYSPLIMHLSAIQLGFVFCGWGLALAYGSAILAHKLEGKYEPKTLLKGSLLVFAIFLIALFFVKIMWLQITLIVLSGLASGLNNALYTSYVMDISPYERSVTSGVYNFVRWLGGAIAPILSGVIGHTVSPQSPFLVGGIVVLVGCIMILIPIRKPVELETKTLS
>NZ_CP020002.1|WP_000276560.1|5666054_5666462_-|MerR-family-transcriptional-regulator
MYKIDEVTKQVGLTKRTLRYYEEIGLIHPPERSEGNIRLYTDEDIARIKRIVEAKEVLGITLQEMQHFLSLKERMEQRRNSENPRDREVIQEIKDMLEKQVQTLDEKMEQMQRVKAELEDSLHRAVTFLESTKGE
>NZ_CP020002.1|WP_000042780.1|5666614_5667340_+|glycerophosphodiester-phosphodiesterase
MSKPLIFAHRGVKGTHPENTMIAFQEAERIGAHGIELDVHLSKDGELVVIHDETVDRTTNGVGLVSEKTVEELQSLDAGSHKAPSFQEAKIPTLREVFIWLSTTNLQLNIELKTDVIHYPNIEEKVVALVREYHLSNQIVFSSFNHDSVSLLAEIAPEIPRAILYDTPIADPIAEAKHREASGLHPNFQLLTKEFVQLAQEQGYVFRPYTINEYKDLQTMIDYGVDVIITDWPARAFELLS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020002_1	1.1\|626221\|26\|NZ_CP020002\|CRISPRCasFinder	626221-626246	26	NZ_CP045855	Agrobacterium sp. MA01 plasmid punnamed1, complete sequence	103187-103212	5	0.808
NZ_CP020002_3	3.1\|5569531\|31\|NZ_CP020002\|CRISPRCasFinder	5569531-5569561	31	JX238501	Bacillus phage phiAGATE, complete genome	124559-124589	8	0.742
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_CP014851	Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence	100650-100683	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	8	0.765
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47181-47214	11	0.676
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47565-47598	11	0.676
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47949-47982	11	0.676
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48333-48366	11	0.676
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48717-48750	11	0.676
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49101-49134	11	0.676
NZ_CP020002_3	3.2\|5569585\|34\|NZ_CP020002\|CRISPRCasFinder	5569585-5569618	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49485-49518	11	0.676

1. spacer 1.1|626221|26|NZ_CP020002|CRISPRCasFinder matches to NZ_CP045855 (Agrobacterium sp. MA01 plasmid punnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

tggtgggcacaatcataacggcggac	CRISPR spacer
atctgggcacaatcatagcggcggaa	Protospacer
   **************.*******

2. spacer 3.1|5569531|31|NZ_CP020002|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

ttcttcttttttgtcactagttgaaccgctt	CRISPR spacer
ctaaccttttttgccactagttaaaccgccc	Protospacer
.*  .********.********.******..

3. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_CP014851 (Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tttatcttcttttttattttctggtttattttcc	Protospacer
.**.****** ****************  * ..*

4. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

5. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

6. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

7. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

8. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

9. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

10. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

11. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

12. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

13. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

14. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

15. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

16. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

17. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

18. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

19. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 8, identity: 0.765

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ********************* **   *.

20. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

21. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

22. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

23. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

24. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

25. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

26. spacer 3.2|5569585|34|NZ_CP020002|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttattttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

256863 : 264815

uncultured_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000917311.1\|256863_257148_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8
WP_079244990.1\|257187_258822_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.0e-156	57.8
WP_000743908.1\|259228_260767_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	8.8e-22	31.7
WP_000833094.1\|261153_262479_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	7.1e-44	29.5
WP_079244991.1\|262624_263326_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.2e-39	36.9
WP_079244992.1\|263309_264815_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.3e-30	29.5

DBSCAN-SWA_2

294145 : 302521

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625687.1\|294145_295453_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.1e-20	25.3
WP_001170545.1\|295541_296261_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000278823.1\|296253_296508_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666782.1\|296504_297188_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_079244996.1\|297171_299391_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	4.4e-163	41.0
WP_000879026.1\|299375_300791_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-55	35.4
WP_001262424.1\|300896_301937_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	5.5e-68	46.3
WP_000088578.1\|301933_302521_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-28	37.4

DBSCAN-SWA_3

1140005 : 1179149

Bacillus_phage(46.51%)

protease,bacteriocin,tail,plate,head,portal,terminase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016097899.1\|1140005_1141784_+	asparagine synthase (glutamine-hydrolyzing)	A0A1V0SGM7	Hokovirus	3.5e-22	27.1
WP_016097900.1\|1141814_1143218_-	recombinase family protein	A0A2I7SDG6	Paenibacillus_phage	3.1e-114	44.8
WP_000289676.1\|1143330_1143549_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_079245173.1\|1143564_1144248_-	LexA family transcriptional regulator	A0A2I6PF08	Staphylococcus_phage	1.4e-16	29.4
WP_016097902.1\|1144398_1144671_+	helix-turn-helix transcriptional regulator	A0A141E0W0	Streptococcus_phage	2.3e-10	50.0
WP_000651465.1\|1145137_1145368_+	hypothetical protein	NA	NA	NA	NA
WP_000959062.1\|1145369_1145582_-	hypothetical protein	NA	NA	NA	NA
WP_079245174.1\|1145636_1145987_+	hypothetical protein	A0A2H4JGP5	uncultured_Caudovirales_phage	2.8e-40	74.1
WP_079245175.1\|1146011_1146659_+	sigma-70 family RNA polymerase sigma factor	W8CYN8	Bacillus_phage	2.9e-99	87.4
WP_000636796.1\|1146719_1146986_+	hypothetical protein	NA	NA	NA	NA
WP_000023094.1\|1147147_1147435_+	hypothetical protein	A0A2H4J830	uncultured_Caudovirales_phage	3.5e-17	48.9
WP_079245176.1\|1147412_1147961_+	hypothetical protein	A0A2H4JFP8	uncultured_Caudovirales_phage	2.3e-89	91.2
WP_079245177.1\|1147963_1148218_+	hypothetical protein	A0A2H4JG95	uncultured_Caudovirales_phage	4.2e-38	92.6
WP_079245178.1\|1148220_1149153_+	AAA family ATPase	A0A2H4JFH2	uncultured_Caudovirales_phage	1.8e-163	95.1
WP_079245179.1\|1149152_1149587_+	DUF669 domain-containing protein	Q9ZXC5	Bacillus_phage	1.3e-50	66.9
WP_079245180.1\|1149656_1152044_+	DNA primase	A0A2H4JEX8	uncultured_Caudovirales_phage	0.0e+00	94.8
WP_079245181.1\|1152336_1152708_+	hypothetical protein	NA	NA	NA	NA
WP_079245182.1\|1152708_1153143_+	hypothetical protein	A0A2H4J832	uncultured_Caudovirales_phage	2.5e-75	95.1
WP_079245183.1\|1153143_1153683_+	nuclease	A0A2H4J819	uncultured_Caudovirales_phage	1.2e-87	90.5
WP_016097914.1\|1153716_1154154_+	hypothetical protein	A0A2H4JBP0	uncultured_Caudovirales_phage	1.3e-71	95.2
WP_042596414.1\|1154226_1154418_+	hypothetical protein	NA	NA	NA	NA
WP_079245184.1\|1154601_1154997_+	sigma-70 family RNA polymerase sigma factor	A0A2H4JFW6	uncultured_Caudovirales_phage	2.0e-58	89.3
WP_079246249.1\|1155262_1155466_+	hypothetical protein	A0A1C8E9B9	Bacillus_phage	2.0e-22	83.1
WP_079245185.1\|1155506_1155848_+	hypothetical protein	A0A1C8E9B7	Bacillus_phage	1.2e-56	93.8
WP_079245186.1\|1155972_1156296_+	hypothetical protein	A0A2H4J758	uncultured_Caudovirales_phage	1.0e-20	50.0
WP_079245187.1\|1156292_1156658_+	HNH endonuclease	A0A2H4JA38	uncultured_Caudovirales_phage	9.0e-42	63.6
WP_000101699.1\|1156777_1157212_+	hypothetical protein	A0A1B2APW6	Phage_Wrath	8.7e-68	95.1
WP_079245188.1\|1157208_1158933_+\|terminase	terminase large subunit	A0A1B2AQ28	Phage_Wrath	0.0e+00	96.3
WP_000523160.1\|1158948_1160154_+\|portal	phage portal protein	A0A1B2APW5	Phage_Wrath	4.1e-216	94.5
WP_079245189.1\|1160122_1160701_+\|head,protease	HK97 family phage prohead protease	A0A2H4J6Z9	uncultured_Caudovirales_phage	9.5e-86	82.0
WP_079245190.1\|1160702_1162076_+\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	5.3e-151	77.2
WP_000998745.1\|1162079_1162340_+\|head,tail	phage gp6-like head-tail connector protein	A0A1C8E967	Bacillus_phage	1.3e-39	93.0
WP_079245191.1\|1162314_1162650_+	hypothetical protein	A0A1C8E986	Bacillus_phage	5.2e-52	95.4
WP_079245192.1\|1162639_1162969_+	hypothetical protein	A0A1B0T6B7	Bacillus_phage	3.8e-55	96.3
WP_079245193.1\|1162968_1163346_+	HK97 gp10 family phage protein	A0A1C8E995	Bacillus_phage	4.8e-62	96.8
WP_079245194.1\|1163357_1163993_+\|tail	phage tail protein	A0A1B1P7Q4	Bacillus_phage	3.3e-116	99.1
WP_079245195.1\|1164004_1164391_+	hypothetical protein	A0A1B1P7Q6	Bacillus_phage	9.5e-66	99.2
WP_006927278.1\|1164429_1164618_+	hypothetical protein	A0A1C8E979	Bacillus_phage	8.2e-31	98.4
WP_079245196.1\|1164634_1168513_+\|tail	phage tail tape measure protein	A0A1B1P7P9	Bacillus_phage	3.9e-252	72.3
WP_070184119.1\|1168514_1169198_+\|tail	phage tail protein	A0A1B1P7Q0	Bacillus_phage	4.8e-129	99.1
WP_145953779.1\|1169194_1171537_+	endopeptidase	A0A1B1P7P0	Bacillus_phage	0.0e+00	99.0
WP_079245197.1\|1171551_1172820_+\|plate	BppU family phage baseplate upper protein	A0A1B0T696	Bacillus_phage	3.9e-225	92.7
WP_000392439.1\|1172882_1173113_+\|bacteriocin	bacteriocin biosynthesis protein	A0A1B1P7Q9	Bacillus_phage	5.7e-34	100.0
WP_079245198.1\|1173109_1174162_+	N-acetylmuramoyl-L-alanine amidase	A0A1C8E990	Bacillus_phage	5.7e-198	97.1
WP_079245199.1\|1174340_1174670_-	hypothetical protein	A0A1C8E989	Bacillus_phage	2.3e-36	79.8
WP_079245200.1\|1174808_1175027_+	hypothetical protein	A0A1C8E991	Bacillus_phage	3.0e-32	95.8
WP_079245201.1\|1175050_1175344_+	hypothetical protein	A0A1C8E992	Bacillus_phage	9.4e-42	88.7
WP_079245202.1\|1175360_1176185_-	cytosolic protein	A0A2H4J969	uncultured_Caudovirales_phage	3.9e-133	89.7
WP_000159538.1\|1176663_1177623_+	ferrochelatase	NA	NA	NA	NA
WP_001069166.1\|1177682_1179149_+	catalase	A0A2K9L572	Tupanvirus	1.7e-123	47.8

DBSCAN-SWA_4

1406984 : 1491426

102

Bacillus_phage(79.63%)

protease,tail,plate,head,holin,portal,terminase,capsid,integrase

attL 1457252:1457271|attR 1493520:1493539

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079245241.1\|1406984_1408871_-	LTA synthase family protein	W6LM83	Streptococcus_phage	1.1e-85	34.1
WP_079245242.1\|1409066_1410176_-\|integrase	site-specific integrase	A0A0U3U8Y8	Bacillus_phage	1.6e-142	76.2
WP_079245243.1\|1410601_1410946_-	helix-turn-helix transcriptional regulator	A0A1B1P888	Bacillus_phage	3.5e-19	43.8
WP_029437996.1\|1411470_1412610_+	hypothetical protein	H0UST6	Bacillus_phage	8.4e-62	37.1
WP_155417052.1\|1412900_1413053_+	hypothetical protein	A0A0A7AQZ6	Bacillus_phage	5.2e-12	74.0
WP_079245244.1\|1413059_1413407_-	helix-turn-helix transcriptional regulator	A0A0A7AR52	Bacillus_phage	5.0e-50	93.0
WP_033694466.1\|1413581_1413800_+	helix-turn-helix transcriptional regulator	A0A0A7AQV9	Bacillus_phage	4.7e-30	90.3
WP_079245245.1\|1413859_1414534_+	Rha family transcriptional regulator	A0A288WFT2	Bacillus_phage	1.2e-58	52.2
WP_029438000.1\|1414571_1414847_+	helix-turn-helix domain-containing protein	A0A0U3ULL9	Bacillus_phage	2.1e-35	86.5
WP_079245248.1\|1415258_1416083_+	replication protein	V5UQV4	Oenococcus_phage	1.8e-42	41.0
WP_016123366.1\|1416021_1416897_+	ATP-binding protein	Q2I8C8	Bacillus_phage	4.3e-66	47.2
WP_079245249.1\|1416912_1417107_+	hypothetical protein	A0A1B1P7U7	Bacillus_phage	1.5e-19	76.6
WP_079245250.1\|1417123_1417534_+	hypothetical protein	NA	NA	NA	NA
WP_079245251.1\|1417747_1418233_-	DUF2321 domain-containing protein	A0A1Q1PVY6	Staphylococcus_phage	5.0e-40	53.6
WP_079245252.1\|1418322_1418601_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	1.8e-13	62.7
WP_079245253.1\|1418593_1418953_+	cell division protein SepF	A0A1B1P7A1	Bacillus_phage	3.2e-31	53.4
WP_050842983.1\|1418973_1419138_+	DUF3954 domain-containing protein	A0A1B0T6B8	Bacillus_phage	4.1e-10	57.7
WP_023522896.1\|1419166_1419418_+	hypothetical protein	A0A0K2CNP4	Brevibacillus_phage	8.4e-07	42.2
WP_079245254.1\|1419437_1419947_+	dUTPase	A0A1L2JY27	Aeribacillus_phage	3.9e-27	44.9
WP_072190986.1\|1420134_1420344_+	hypothetical protein	NA	NA	NA	NA
WP_079245255.1\|1420359_1420740_+	hypothetical protein	NA	NA	NA	NA
WP_079245256.1\|1421012_1421405_+	hypothetical protein	A0A0S2MVH4	Bacillus_phage	3.2e-29	69.6
WP_016077632.1\|1421441_1421831_+	hypothetical protein	NA	NA	NA	NA
WP_079245257.1\|1421867_1422848_+	site-specific DNA-methyltransferase	A0A2H4JD00	uncultured_Caudovirales_phage	2.5e-118	61.5
WP_079245258.1\|1423617_1423848_-	CGEA protein	NA	NA	NA	NA
WP_079246255.1\|1424208_1424433_+	hypothetical protein	I7J6W4	Bacillus_phage	2.1e-25	77.0
WP_079245259.1\|1424467_1425064_+	hypothetical protein	A0A0F6SJ62	Sinorhizobium_phage	9.0e-15	31.8
WP_079245260.1\|1425093_1425324_+	hypothetical protein	NA	NA	NA	NA
WP_079245261.1\|1425432_1425783_+	hypothetical protein	A0A1B1P8B5	Bacillus_phage	2.8e-08	38.8
WP_049106871.1\|1425812_1425935_+	DUF3983 domain-containing protein	NA	NA	NA	NA
WP_079245263.1\|1426241_1426712_+	ArpU family transcriptional regulator	A0A1B1P744	Bacillus_phage	1.3e-48	62.5
WP_079245264.1\|1426708_1427251_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1P746	Bacillus_phage	1.6e-95	98.9
WP_021727596.1\|1427854_1428046_+	hypothetical protein	Q2I8B4	Bacillus_phage	1.3e-20	82.5
WP_079245265.1\|1428045_1428540_+	hypothetical protein	NA	NA	NA	NA
WP_145953850.1\|1428529_1428754_+	hypothetical protein	A0A1B1P745	Bacillus_phage	1.8e-24	81.1
WP_079245267.1\|1428760_1429057_+	hypothetical protein	Q2I8B8	Bacillus_phage	1.6e-09	55.6
WP_021727591.1\|1429207_1429453_+	hypothetical protein	A0A288WG15	Bacillus_phage	7.9e-18	61.7
WP_079246256.1\|1429566_1429761_+	HNH endonuclease	A0A1B1P757	Bacillus_phage	2.1e-29	90.6
WP_021727589.1\|1429763_1430072_+	hypothetical protein	A0A1B1P767	Bacillus_phage	1.6e-44	90.4
WP_061685182.1\|1430179_1430500_+	hypothetical protein	A0A1B1P762	Bacillus_phage	5.5e-43	84.9
WP_079245268.1\|1430483_1432166_+\|terminase	terminase large subunit	A0A1B1P766	Bacillus_phage	1.8e-310	94.3
WP_079245269.1\|1432180_1433347_+\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	1.0e-208	93.2
WP_079246257.1\|1433492_1434053_+\|protease	Clp protease ClpP	A0A0U4B047	Bacillus_phage	4.2e-38	49.5
WP_079245270.1\|1434094_1435258_+\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	2.8e-84	42.9
WP_076775023.1\|1435398_1435695_+	hypothetical protein	A0A1B1P751	Bacillus_phage	6.8e-48	99.0
WP_079245271.1\|1435675_1436032_+\|head	phage head closure protein	A0A1B1P760	Bacillus_phage	5.7e-57	94.9
WP_079246258.1\|1436048_1436426_+	hypothetical protein	A0A1B1P759	Bacillus_phage	2.6e-60	96.0
WP_033707118.1\|1436412_1436841_+	hypothetical protein	A0A1B1P769	Bacillus_phage	3.2e-70	95.1
WP_079245272.1\|1436842_1437427_+\|tail	phage tail protein	A0A1B1P778	Bacillus_phage	6.8e-92	84.5
WP_079245273.1\|1437496_1437958_+	hypothetical protein	A0A1B1P772	Bacillus_phage	1.7e-74	93.5
WP_159451453.1\|1437984_1438122_+	hypothetical protein	NA	NA	NA	NA
WP_079245274.1\|1438136_1439750_+	hypothetical protein	A0A1B1P775	Bacillus_phage	4.1e-110	89.9
WP_079245275.1\|1439964_1443060_+	hypothetical protein	A0A1B1P764	Bacillus_phage	1.8e-186	79.9
WP_079245276.1\|1443061_1443745_+\|tail	phage tail protein	A0A1B1P761	Bacillus_phage	2.9e-126	98.2
WP_079245277.1\|1443744_1446150_+	endopeptidase	A0A1B1P770	Bacillus_phage	0.0e+00	98.1
WP_079245278.1\|1446164_1447436_+\|plate	BppU family phage baseplate upper protein	A0A1B1P7N9	Bacillus_phage	1.1e-230	95.0
WP_145953782.1\|1447558_1448518_+\|integrase	tyrosine-type recombinase/integrase	A0A0S2GLC8	Bacillus_phage	1.9e-176	96.2
WP_000373869.1\|1448533_1448959_+\|holin	phage holin family protein	A0A1B1P787	Bacillus_phage	9.7e-72	99.3
WP_079245280.1\|1448958_1449894_+	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	5.5e-184	97.7
WP_079245281.1\|1450967_1451234_-	hypothetical protein	NA	NA	NA	NA
WP_050843053.1\|1451249_1451441_-	hypothetical protein	NA	NA	NA	NA
WP_001228823.1\|1452001_1452397_+	DUF3888 domain-containing protein	NA	NA	NA	NA
WP_079245282.1\|1452848_1454165_+	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_000116158.1\|1454460_1454604_+	YezD family protein	NA	NA	NA	NA
WP_079245283.1\|1454691_1455396_+	phosphoadenylyl-sulfate reductase	NA	NA	NA	NA
WP_000108784.1\|1455434_1456571_+	sulfate adenylyltransferase	A0A2K9L0F0	Tupanvirus	1.2e-44	29.7
WP_000380490.1\|1456583_1457195_+	adenylyl-sulfate kinase	NA	NA	NA	NA
1457252:1457271	attL	NA	NA	NA	NA
WP_000119600.1\|1457287_1458910_+	ferredoxin--nitrite reductase	NA	NA	NA	NA
WP_000424930.1\|1458920_1459121_+	DUF3906 family protein	NA	NA	NA	NA
WP_000521277.1\|1459207_1459984_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_079245284.1\|1459985_1460738_+	sirohydrochlorin chelatase	NA	NA	NA	NA
WP_000283361.1\|1460712_1461327_+	NAD(P)-binding protein	NA	NA	NA	NA
WP_000665434.1\|1461751_1463107_+	sodium-dependent transporter	NA	NA	NA	NA
WP_000726091.1\|1463392_1464667_-	M23 family metallopeptidase	A0A2D0ZM66	Rhodococcus_phage	2.0e-11	36.5
WP_000821134.1\|1465161_1466436_+	glutamate/aspartate:proton symporter GltP	NA	NA	NA	NA
WP_000824630.1\|1466504_1467023_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_000665498.1\|1467343_1468660_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_079245285.1\|1468841_1469198_+	flagellar basal body rod protein	NA	NA	NA	NA
WP_000814131.1\|1469245_1469908_+	PspA/IM30 family protein	NA	NA	NA	NA
WP_000716094.1\|1470015_1470756_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_079245286.1\|1470755_1471811_+	sensor histidine kinase	NA	NA	NA	NA
WP_000598702.1\|1471807_1472440_+	response regulator transcription factor	NA	NA	NA	NA
WP_118961699.1\|1472497_1472836_+	DUF3922 domain-containing protein	NA	NA	NA	NA
WP_079245287.1\|1472860_1474207_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_000880630.1\|1474794_1475004_+	hypothetical protein	NA	NA	NA	NA
WP_079245288.1\|1475044_1475821_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000677057.1\|1475929_1476781_+	hypothetical protein	NA	NA	NA	NA
WP_001053359.1\|1476979_1477177_-	hypothetical protein	NA	NA	NA	NA
WP_000794496.1\|1477325_1478423_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_000735433.1\|1478537_1479056_+	hypothetical protein	NA	NA	NA	NA
WP_000947319.1\|1479215_1480424_+	NO-inducible flavohemoprotein	NA	NA	NA	NA
WP_000600585.1\|1480456_1480969_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_000882911.1\|1481139_1481367_+	hypothetical protein	NA	NA	NA	NA
WP_079245289.1\|1481660_1482461_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_000380276.1\|1482578_1483577_-	inorganic phosphate transporter	NA	NA	NA	NA
WP_000231445.1\|1483588_1484209_-	DUF47 domain-containing protein	NA	NA	NA	NA
WP_079245290.1\|1484520_1486563_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_001265587.1\|1486643_1487072_-	hypothetical protein	NA	NA	NA	NA
WP_063675147.1\|1488102_1489368_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	1.3e-15	24.5
WP_000897362.1\|1489519_1490365_+	DUF72 domain-containing protein	NA	NA	NA	NA
WP_001094856.1\|1490579_1490774_-	DUF3924 domain-containing protein	NA	NA	NA	NA
WP_000806236.1\|1490895_1491426_-\|integrase	tyrosine-type recombinase/integrase	A3F636	Streptococcus_phage	1.1e-24	39.4
1493520:1493539	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1746034 : 1762853

Brevibacillus_phage(100.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000465973.1\|1746034_1746487_+	hypothetical protein	A0A0K2CP30	Brevibacillus_phage	8.9e-23	43.0
WP_000077127.1\|1746486_1747575_+	hypothetical protein	A0A0K2CNX7	Brevibacillus_phage	2.7e-94	55.6
WP_000004091.1\|1747807_1748278_+	hypothetical protein	A0A0K2CPC8	Brevibacillus_phage	8.1e-35	52.9
WP_000743722.1\|1748364_1748607_+	hypothetical protein	A0A0K2CP74	Brevibacillus_phage	2.7e-18	55.0
WP_079245328.1\|1748679_1754031_+\|tail	phage tail tape measure protein	A0A0K2CPN3	Brevibacillus_phage	1.6e-142	26.0
WP_000068594.1\|1754089_1754707_+	S-layer homology domain-containing protein	A0A0K2CPJ2	Brevibacillus_phage	1.1e-71	61.2
WP_001126627.1\|1754709_1755783_+	hypothetical protein	A0A0K2CP35	Brevibacillus_phage	9.1e-74	40.3
WP_001134178.1\|1755796_1759003_+	M23 family metallopeptidase	A0A0K2CNY2	Brevibacillus_phage	3.7e-06	50.0
WP_079245329.1\|1759080_1759797_+	hypothetical protein	NA	NA	NA	NA
WP_000007797.1\|1759811_1760252_+	hypothetical protein	NA	NA	NA	NA
WP_001145942.1\|1760267_1762853_+	hypothetical protein	A0A0K2CPJ7	Brevibacillus_phage	1.6e-31	44.2

DBSCAN-SWA_6

1798476 : 1807862

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000177370.1\|1798476_1799184_-	DNA polymerase I	A0A0K2CNW2	Brevibacillus_phage	1.1e-64	53.9
WP_000781409.1\|1799352_1799757_-	hypothetical protein	NA	NA	NA	NA
WP_002083222.1\|1800380_1801775_-	hypothetical protein	A0A0K2CP19	Brevibacillus_phage	1.2e-102	46.1
WP_000207533.1\|1801861_1802521_-	hypothetical protein	A0A0K2CPH8	Brevibacillus_phage	4.7e-57	56.9
WP_001090550.1\|1802983_1803541_-	sigma-70 family RNA polymerase sigma factor	A0A0K2CPD2	Brevibacillus_phage	2.4e-25	41.1
WP_001167934.1\|1803568_1804645_-	toprim domain-containing protein	A0A0K2CNW6	Brevibacillus_phage	1.3e-104	54.0
WP_001139152.1\|1804669_1805962_-	DNA helicase	A0A0K2CP24	Brevibacillus_phage	1.1e-139	57.9
WP_001005180.1\|1806441_1807212_-	ATP-binding protein	A0A0K2CNX1	Brevibacillus_phage	3.3e-62	48.4
WP_000278516.1\|1807271_1807862_-	helix-turn-helix domain-containing protein	A0A0K2CNS5	Brevibacillus_phage	1.0e-26	43.7

DBSCAN-SWA_7

2035295 : 2089222

Bacillus_phage(68.97%)

tail,transposase,holin,portal,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079245061.1\|2035295_2036492_-\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	5.6e-24	25.9
WP_079245386.1\|2036933_2038490_+	AAA family ATPase	A7KV18	Bacillus_phage	1.8e-22	31.8
WP_079245387.1\|2038503_2038806_+	hypothetical protein	NA	NA	NA	NA
WP_079245388.1\|2038805_2039039_+	hypothetical protein	NA	NA	NA	NA
WP_079245389.1\|2039052_2039688_+	chromosome partitioning protein ParA	A7KV15	Bacillus_phage	8.4e-27	35.0
WP_061884020.1\|2039704_2040070_+	hypothetical protein	NA	NA	NA	NA
WP_145953789.1\|2040069_2041128_+	exonuclease SbcD	NA	NA	NA	NA
WP_042597771.1\|2041124_2041427_+	hypothetical protein	NA	NA	NA	NA
WP_145953790.1\|2041419_2041971_+	hypothetical protein	NA	NA	NA	NA
WP_000371313.1\|2041980_2042499_+	hypothetical protein	NA	NA	NA	NA
WP_145953853.1\|2042582_2044175_+	DEAD/DEAH box helicase family protein	A0A1B0Z0P8	Vibrio_phage	3.7e-15	24.4
WP_079245392.1\|2044264_2044543_+	hypothetical protein	NA	NA	NA	NA
WP_145953791.1\|2044542_2045286_+	hypothetical protein	NA	NA	NA	NA
WP_079245394.1\|2045305_2048392_+	DNA primase	A0A1L4BKL0	Thermus_phage	4.7e-14	28.6
WP_145953792.1\|2048415_2050842_+	bifunctional 3'-5' exonuclease/DNA polymerase	F8WQ35	Bacillus_phage	3.0e-32	23.6
WP_000532406.1\|2050845_2051118_+	hypothetical protein	NA	NA	NA	NA
WP_078993311.1\|2051080_2051338_+	hypothetical protein	NA	NA	NA	NA
WP_145953793.1\|2051363_2051729_+	hypothetical protein	NA	NA	NA	NA
WP_159451458.1\|2051725_2051872_+	hypothetical protein	NA	NA	NA	NA
WP_145953794.1\|2051871_2052195_+	hypothetical protein	NA	NA	NA	NA
WP_079245396.1\|2052191_2052731_+	hypothetical protein	R9TQ23	Paenibacillus_phage	8.7e-25	37.6
WP_079245397.1\|2052745_2053522_+	hypothetical protein	NA	NA	NA	NA
WP_079245398.1\|2054010_2054991_+	site-specific DNA-methyltransferase	A0A2H4JD00	uncultured_Caudovirales_phage	6.1e-117	62.7
WP_079245399.1\|2055720_2056041_+	hypothetical protein	A0A0A7AR06	Bacillus_phage	2.7e-26	53.8
WP_079245400.1\|2056076_2056397_+	hypothetical protein	A0A0S2MVI8	Bacillus_phage	6.3e-15	48.5
WP_079245402.1\|2056438_2056882_+	hypothetical protein	S5MUC4	Brevibacillus_phage	1.3e-10	56.6
WP_079245403.1\|2056878_2057532_+	hypothetical protein	NA	NA	NA	NA
WP_079245405.1\|2057528_2057711_+	hypothetical protein	NA	NA	NA	NA
WP_079245407.1\|2057707_2058025_+	transglycosylase	NA	NA	NA	NA
WP_079245408.1\|2058041_2058980_+	hypothetical protein	NA	NA	NA	NA
WP_079245409.1\|2058982_2059129_+	BC1881 family protein	NA	NA	NA	NA
WP_079245411.1\|2059255_2059450_+	hypothetical protein	NA	NA	NA	NA
WP_042597802.1\|2059851_2060133_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	2.7e-14	57.1
WP_042597805.1\|2060134_2060332_+	hypothetical protein	A0A1L2JY50	Aeribacillus_phage	6.6e-07	49.1
WP_145953795.1\|2060328_2060526_+	hypothetical protein	NA	NA	NA	NA
WP_145953796.1\|2060522_2060771_+	hypothetical protein	NA	NA	NA	NA
WP_000200016.1\|2061285_2061615_+	hypothetical protein	NA	NA	NA	NA
WP_000196739.1\|2061874_2062255_+	hypothetical protein	NA	NA	NA	NA
WP_001086032.1\|2062968_2063397_+	hypothetical protein	A0A2H4J6Z8	uncultured_Caudovirales_phage	1.2e-32	51.1
WP_079245413.1\|2063413_2065129_+\|terminase	phage terminase large subunit	A0A142F1L6	Bacillus_phage	1.9e-150	52.7
WP_079245414.1\|2065145_2066663_+\|portal	phage portal protein	A0A142F1L7	Bacillus_phage	1.5e-66	29.6
WP_140158368.1\|2066721_2067504_+	scaffolding protein	Q4ZC70	Staphylococcus_virus	9.7e-09	40.0
WP_075717831.1\|2067564_2068689_+	DUF5309 family protein	NA	NA	NA	NA
WP_000027968.1\|2068738_2068963_+	hypothetical protein	NA	NA	NA	NA
WP_025118134.1\|2068991_2069333_+	hypothetical protein	NA	NA	NA	NA
WP_079245416.1\|2069337_2070144_+	hypothetical protein	NA	NA	NA	NA
WP_079245417.1\|2070147_2070522_+	hypothetical protein	NA	NA	NA	NA
WP_079245418.1\|2070884_2071292_+	hypothetical protein	NA	NA	NA	NA
WP_000852562.1\|2071305_2071812_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_079245419.1\|2071835_2072195_+	hypothetical protein	A0A0A7AQ61	Bacillus_phage	2.7e-38	81.0
WP_079245420.1\|2072181_2072397_+	hypothetical protein	A0A0S2MV92	Bacillus_phage	3.3e-28	92.8
WP_000818630.1\|2072468_2072846_+	hypothetical protein	NA	NA	NA	NA
WP_145953797.1\|2072935_2073190_+	hypothetical protein	NA	NA	NA	NA
WP_079245424.1\|2077137_2078634_+\|tail	phage tail family protein	A0A0S2MV63	Bacillus_phage	6.4e-219	80.4
WP_079245425.1\|2078630_2082653_+	hypothetical protein	A0A0U3SD62	Bacillus_phage	0.0e+00	77.1
WP_079245426.1\|2082691_2082976_+	hypothetical protein	NA	NA	NA	NA
WP_079245428.1\|2082990_2083221_+\|holin	phage holin	A0A0S2MVE8	Bacillus_phage	5.7e-26	77.3
WP_079245429.1\|2083234_2084068_+	N-acetylmuramoyl-L-alanine amidase	A0A0S2GLD4	Bacillus_phage	1.0e-149	88.1
WP_079245430.1\|2084121_2084388_-	hypothetical protein	NA	NA	NA	NA
WP_079245431.1\|2084667_2085270_-	hypothetical protein	NA	NA	NA	NA
WP_000578036.1\|2085369_2085606_-	helix-turn-helix transcriptional regulator	Q2I8D9	Bacillus_phage	9.0e-19	57.9
WP_145953798.1\|2085762_2085885_+	DUF3961 domain-containing protein	Q3HKZ4	Bacillus_phage	4.1e-07	59.5
WP_079245436.1\|2086527_2086719_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_079246274.1\|2086875_2087178_+	hypothetical protein	A0A288WG08	Bacillus_phage	7.5e-26	55.1
WP_079245437.1\|2087174_2087357_+	hypothetical protein	Q2I8E2	Bacillus_phage	8.8e-22	90.0
WP_079245438.1\|2087472_2088657_+	cell division protein FtsK	A0A288WFS1	Bacillus_phage	4.3e-141	63.3
WP_079245439.1\|2088598_2089222_+	hypothetical protein	H0USY2	Bacillus_phage	4.1e-95	79.6

DBSCAN-SWA_8

2124442 : 2133331

Bacillus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063675233.1\|2124442_2125729_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.8e-10	30.6
WP_079245451.1\|2125828_2126593_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_079245452.1\|2126828_2128589_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.2e-274	98.8
WP_016082005.1\|2128673_2129351_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.9e-123	99.1
WP_142307883.1\|2129347_2130421_+	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	4.4e-185	96.9
WP_000818985.1\|2130648_2131368_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_145953799.1\|2131470_2131935_+	O-methyltransferase	W8CYT3	Bacillus_phage	9.0e-71	97.8
WP_079245455.1\|2132461_2133331_+	aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	1.3e-65	44.2

DBSCAN-SWA_9

2314288 : 2322316

Bacillus_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000427801.1\|2314288_2314564_+	stage V sporulation protein S	J9PTX7	Bacillus_phage	2.9e-08	41.2
WP_000478850.1\|2314762_2315026_+	hypothetical protein	A0A218KBU4	Bacillus_phage	4.4e-06	38.9
WP_145953776.1\|2315667_2316814_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.4e-48	41.8
WP_079245479.1\|2316822_2317188_-	YolD-like family protein	A0A2H4JEH6	uncultured_Caudovirales_phage	7.0e-10	27.5
WP_017763084.1\|2317378_2318452_+	tetratricopeptide repeat protein	A0A2H4J8G3	uncultured_Caudovirales_phage	2.6e-73	42.0
WP_000709202.1\|2318448_2318574_+	hypothetical protein	NA	NA	NA	NA
WP_044784193.1\|2318893_2319667_-	hypothetical protein	NA	NA	NA	NA
WP_044784192.1\|2319776_2320424_+	HD domain-containing protein	S4W232	Pandoravirus	3.5e-12	29.1
WP_000783164.1\|2320420_2322316_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2H4UUX5	Bodo_saltans_virus	4.9e-46	25.3

DBSCAN-SWA_10

3062723 : 3116511

Bacillus_phage(89.58%)

protease,coat,tail,transposase,head,portal,terminase,capsid,integrase

attL 3068594:3068610|attR 3120457:3120473

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000415813.1\|3062723_3063176_-\|coat	spore coat protein	NA	NA	NA	NA
WP_000342252.1\|3063190_3063391_-\|coat	spore coat protein	NA	NA	NA	NA
WP_000332789.1\|3063758_3064307_-\|coat	spore coat protein	NA	NA	NA	NA
WP_000027167.1\|3064964_3065396_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000581062.1\|3065749_3066520_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000340384.1\|3066776_3067556_-	hypothetical protein	NA	NA	NA	NA
WP_001062742.1\|3067808_3068129_+	hypothetical protein	NA	NA	NA	NA
WP_000229634.1\|3068208_3069723_-	MFS transporter	NA	NA	NA	NA
3068594:3068610	attL	NA	NA	NA	NA
WP_000401028.1\|3069746_3070454_-	hypothetical protein	NA	NA	NA	NA
WP_001258382.1\|3070472_3071183_-	polymer-forming cytoskeletal protein	NA	NA	NA	NA
WP_000102243.1\|3071196_3071820_-	YhbD family protein	NA	NA	NA	NA
WP_000470218.1\|3071980_3073717_-	SgrR family transcriptional regulator	NA	NA	NA	NA
WP_079245620.1\|3075184_3076012_+	cytosolic protein	A0A2H4J6G7	uncultured_Caudovirales_phage	1.6e-102	70.2
WP_079245621.1\|3076021_3076642_-	hypothetical protein	H0USY2	Bacillus_phage	2.8e-112	95.1
WP_079245622.1\|3076583_3077765_-	cell division protein FtsK	H0USY1	Bacillus_phage	5.8e-215	94.1
WP_159451460.1\|3077989_3078079_-	hypothetical protein	NA	NA	NA	NA
WP_079245623.1\|3078059_3078377_-	hypothetical protein	H0USY0	Bacillus_phage	2.4e-51	97.1
WP_079245624.1\|3078559_3078757_+	helix-turn-helix transcriptional regulator	A0A288WG80	Bacillus_phage	3.4e-19	76.2
WP_079245625.1\|3078765_3078945_+	hypothetical protein	NA	NA	NA	NA
WP_079245626.1\|3078950_3079538_+	type IV secretory system conjugative DNA transfer family protein	A0A288WG09	Bacillus_phage	1.7e-98	90.2
WP_079245627.1\|3079606_3079936_+	hypothetical protein	A0A0S2GLG3	Bacillus_phage	7.3e-51	93.6
WP_079245628.1\|3079974_3081030_-	N-acetylmuramoyl-L-alanine amidase	D3WK93	Bacillus_phage	1.8e-191	94.0
WP_044798115.1\|3081026_3081266_-	hypothetical protein	A0A288WFV1	Bacillus_phage	1.2e-31	94.9
WP_079245061.1\|3081563_3082760_+\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	5.6e-24	25.9
WP_079245629.1\|3082961_3083195_-	hypothetical protein	A0A2H4J382	uncultured_Caudovirales_phage	3.9e-14	87.8
WP_079245630.1\|3083362_3083812_-	hypothetical protein	A0A2H4J6F8	uncultured_Caudovirales_phage	6.7e-79	96.6
WP_079245631.1\|3083834_3087845_-	hypothetical protein	H0USX5	Bacillus_phage	0.0e+00	88.9
WP_079245632.1\|3087841_3089323_-\|tail	phage tail protein	W8CYY9	Bacillus_phage	8.4e-280	93.7
WP_079245633.1\|3089337_3093189_-\|tail	phage tail tape measure protein	A0A288WG88	Bacillus_phage	0.0e+00	96.2
WP_044798120.1\|3093411_3093729_-	hypothetical protein	A0A288WGA9	Bacillus_phage	4.9e-52	97.1
WP_044798121.1\|3093776_3094385_-\|tail	tail protein	A0A288WG55	Bacillus_phage	8.1e-104	98.5
WP_044798123.1\|3094385_3094745_-	DUF3168 domain-containing protein	Q2I8F3	Bacillus_phage	3.2e-60	95.8
WP_044798124.1\|3094741_3095182_-	HK97 family phage protein	A0A288WGB7	Bacillus_phage	4.2e-78	100.0
WP_044798125.1\|3095174_3095498_-\|head	phage head closure protein	Q2I8F5	Bacillus_phage	2.2e-55	97.2
WP_044798126.1\|3095494_3095785_-\|head,tail	phage gp6-like head-tail connector protein	A0A288WGQ6	Bacillus_phage	1.1e-45	96.9
WP_079245634.1\|3095802_3096972_-\|capsid	phage major capsid protein	A0A288WG01	Bacillus_phage	3.9e-195	92.1
WP_044798129.1\|3097010_3097631_-\|head,protease	HK97 family phage prohead protease	Q2I8F8	Bacillus_phage	1.2e-110	98.1
WP_079245635.1\|3097593_3098892_-\|portal	phage portal protein	Q2LIC9	Bacillus_phage	3.2e-243	98.4
WP_044798130.1\|3098907_3100605_-\|terminase	terminase large subunit	A0A288WFW5	Bacillus_phage	0.0e+00	98.8
WP_044798131.1\|3100601_3101087_-\|terminase	phage terminase small subunit P27 family	Q2I8G1	Bacillus_phage	6.5e-80	96.9
WP_044798132.1\|3101187_3101571_-	HNH endonuclease	Q2I8B2	Bacillus_phage	2.6e-68	97.6
WP_079246301.1\|3101640_3101907_-	hypothetical protein	H0USV8	Bacillus_phage	6.8e-15	53.9
WP_079245636.1\|3102067_3102256_-	hypothetical protein	A0A0S2GLH7	Bacillus_phage	1.4e-11	66.0
WP_079245637.1\|3102454_3102709_-	hypothetical protein	A0A288WG25	Bacillus_phage	1.1e-41	97.6
WP_079245638.1\|3102728_3102920_-	hypothetical protein	A0A288WFV5	Bacillus_phage	1.1e-19	76.2
WP_079245639.1\|3102906_3103248_-	hypothetical protein	Q2I8B8	Bacillus_phage	7.9e-24	81.4
WP_079245640.1\|3103252_3103474_-	hypothetical protein	Q2LI85	Bacillus_phage	1.3e-30	93.2
WP_079246302.1\|3103480_3103705_-	hypothetical protein	Q3HKX2	Bacillus_phage	2.0e-28	87.8
WP_044821902.1\|3103824_3104220_-	sigma-70 family RNA polymerase sigma factor	A0A288WFT8	Bacillus_phage	6.3e-65	96.9
WP_001258960.1\|3104395_3104518_-	DUF3983 domain-containing protein	A0A288WG42	Bacillus_phage	8.5e-13	95.0
WP_079245641.1\|3104671_3104860_-	hypothetical protein	Q3HKX5	Bacillus_phage	1.2e-21	88.7
WP_153599617.1\|3105237_3105396_-	hypothetical protein	NA	NA	NA	NA
WP_044798137.1\|3105435_3105735_-	hypothetical protein	A0A0M4REQ3	Bacillus_phage	2.0e-39	80.8
WP_044798138.1\|3105897_3106410_-	hypothetical protein	NA	NA	NA	NA
WP_044798140.1\|3106718_3107261_-	hypothetical protein	A0A288WGA4	Bacillus_phage	1.9e-96	95.0
WP_079245643.1\|3107317_3107794_-	hypothetical protein	A0A288WFT9	Bacillus_phage	1.4e-90	94.3
WP_079245644.1\|3107790_3108537_-	sigma-70 family RNA polymerase sigma factor	Q2I8C6	Bacillus_phage	1.4e-97	73.4
WP_079245645.1\|3108529_3108757_-	hypothetical protein	C7DTL1	Bacillus_phage	1.6e-25	73.3
WP_079245646.1\|3108756_3109638_-	ATP-binding protein	A0A0S2SXI8	Bacillus_phage	1.6e-28	34.5
WP_079245647.1\|3109649_3110423_-	replication protein	A0A1W6JNI1	Staphylococcus_phage	4.4e-54	48.2
WP_079245648.1\|3110552_3111434_-	hypothetical protein	NA	NA	NA	NA
WP_079245649.1\|3111457_3112132_-	Rha family transcriptional regulator	A0A288WFT2	Bacillus_phage	4.3e-82	66.1
WP_079245650.1\|3112340_3112529_-	helix-turn-helix domain-containing protein	A0A1B2APY7	Phage_Wrath	1.0e-20	79.0
WP_021727906.1\|3112710_3112917_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_079245651.1\|3113075_3113417_+	helix-turn-helix transcriptional regulator	H0UST7	Bacillus_phage	1.1e-09	33.3
WP_079245652.1\|3113828_3114995_-	hypothetical protein	NA	NA	NA	NA
WP_079245653.1\|3115449_3116511_+\|integrase	site-specific integrase	H0UST3	Bacillus_phage	3.5e-163	79.9
3120457:3120473	attR	NA	NA	NA	NA

DBSCAN-SWA_11

4593203 : 4700185

112

Bacillus_phage(50.91%)

protease,coat,bacteriocin,portal,tail,head,tRNA,plate,terminase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001266969.1\|4593203_4593644_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_001262795.1\|4593660_4595844_-	GTP diphosphokinase	A0A1B1IUF0	uncultured_Mediterranean_phage	2.4e-12	36.5
WP_000346215.1\|4596054_4596567_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	8.5e-30	43.8
WP_000941227.1\|4596614_4598954_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.9e-85	32.8
WP_000409739.1\|4599055_4599949_-	cation transporter	NA	NA	NA	NA
WP_001119057.1\|4600105_4602370_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	7.4e-33	35.3
WP_000884549.1\|4602639_4602924_-	histidine kinase	NA	NA	NA	NA
WP_000198293.1\|4603109_4604669_+	stage V sporulation protein B	NA	NA	NA	NA
WP_000454822.1\|4604749_4605397_-	DUF421 domain-containing protein	NA	NA	NA	NA
WP_000349145.1\|4605500_4605884_+	TIGR04086 family membrane protein	NA	NA	NA	NA
WP_000991113.1\|4605920_4606181_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.8e-05	43.9
WP_000125365.1\|4606208_4607348_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.1e-82	42.3
WP_000354016.1\|4607360_4608413_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_000138162.1\|4608432_4608633_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_000344464.1\|4608629_4609631_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	6.8e-07	26.3
WP_000464512.1\|4609636_4610254_-	Holliday junction DNA helicase RuvA	NA	NA	NA	NA
WP_000823610.1\|4610442_4611387_+	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000871202.1\|4611398_4611929_-	BofC protein	NA	NA	NA	NA
WP_000874881.1\|4612410_4612791_+	hypothetical protein	NA	NA	NA	NA
WP_001093530.1\|4612824_4613472_-	hypothetical protein	NA	NA	NA	NA
WP_079245941.1\|4613650_4615618_-\|coat	spore coat assembly protein ExsA	NA	NA	NA	NA
WP_153578016.1\|4615639_4615816_-	hypothetical protein	NA	NA	NA	NA
WP_000025283.1\|4615844_4616951_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_001092241.1\|4616982_4617816_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_001138543.1\|4617835_4619365_-	L-aspartate oxidase	NA	NA	NA	NA
WP_000973781.1\|4619517_4620660_+	aminotransferase class V-fold PLP-dependent enzyme	A0A1X7QGF3	Faustovirus	8.5e-30	29.2
WP_000812273.1\|4620659_4621202_+	transcription repressor NadR	NA	NA	NA	NA
WP_000511662.1\|4621281_4621929_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_000796366.1\|4622121_4622592_+	hypothetical protein	NA	NA	NA	NA
WP_000621701.1\|4622769_4623621_-	prephenate dehydratase	NA	NA	NA	NA
WP_079245942.1\|4623717_4625628_-	ABC transporter permease	NA	NA	NA	NA
WP_001011409.1\|4625677_4627600_-	ABC transporter permease	NA	NA	NA	NA
WP_000114530.1\|4627574_4628351_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.6e-19	31.0
WP_000865417.1\|4628444_4629527_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_002082113.1\|4629516_4630224_-	response regulator transcription factor	NA	NA	NA	NA
WP_000497121.1\|4630413_4631700_-	GTPase ObgE	NA	NA	NA	NA
WP_001003585.1\|4631704_4632247_-	sporulation protein	NA	NA	NA	NA
WP_000944957.1\|4632310_4632601_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_002082112.1\|4632604_4632949_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_000270907.1\|4632960_4633269_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_079245943.1\|4633438_4634827_-	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_000599046.1\|4634894_4635755_-	stage IV sporulation protein SpoIVFB	NA	NA	NA	NA
WP_000797477.1\|4635747_4636494_-	stage IV sporulation protein SpoIVFA	NA	NA	NA	NA
WP_000503309.1\|4636627_4637425_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_000391514.1\|4637427_4638114_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_000975762.1\|4638149_4638695_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_001135484.1\|4638709_4639561_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_000466736.1\|4639602_4640622_-	rod shape-determining protein MreB	NA	NA	NA	NA
WP_145953834.1\|4640779_4641184_-	DNA repair protein RadC	NA	NA	NA	NA
WP_079245944.1\|4641291_4642125_+	cytosolic protein	A0A2H4J6G7	uncultured_Caudovirales_phage	2.5e-127	86.3
WP_079245945.1\|4642141_4642435_-	hypothetical protein	A0A1C8E992	Bacillus_phage	9.1e-45	93.8
WP_044797844.1\|4642458_4642677_-	hypothetical protein	A0A1C8E991	Bacillus_phage	7.0e-34	100.0
WP_079245946.1\|4642815_4643148_+	hypothetical protein	A0A1B2AQ49	Phage_Wrath	1.4e-25	60.9
WP_079245947.1\|4643326_4644379_-	N-acetylmuramoyl-L-alanine amidase	A0A1C8E990	Bacillus_phage	4.0e-199	98.0
WP_000392439.1\|4644375_4644606_-\|bacteriocin	bacteriocin biosynthesis protein	A0A1B1P7Q9	Bacillus_phage	5.7e-34	100.0
WP_079245948.1\|4644668_4645937_-\|plate	BppU family phage baseplate upper protein	A0A1B0T696	Bacillus_phage	3.0e-225	92.2
WP_079245949.1\|4645951_4648294_-	endopeptidase	A0A1B1P7P0	Bacillus_phage	0.0e+00	96.4
WP_079245950.1\|4648290_4648974_-\|tail	phage tail protein	A0A1C8EA72	Bacillus_phage	1.8e-128	98.2
WP_079245951.1\|4648975_4652854_-\|tail	phage tail tape measure protein	A0A1B1P7P9	Bacillus_phage	9.4e-238	71.2
WP_006927278.1\|4652870_4653059_-	hypothetical protein	A0A1C8E979	Bacillus_phage	8.2e-31	98.4
WP_000113340.1\|4653097_4653484_-	hypothetical protein	A0A1C8E984	Bacillus_phage	3.6e-65	99.2
WP_016125430.1\|4653495_4654131_-\|tail	phi13 family phage major tail protein	A0A1C8E980	Bacillus_phage	4.8e-115	98.6
WP_060852321.1\|4654142_4654520_-	hypothetical protein	A0A2H4JDG0	uncultured_Caudovirales_phage	5.1e-56	87.2
WP_061884612.1\|4654519_4654849_-	hypothetical protein	A0A1B1P7P2	Bacillus_phage	2.6e-56	98.2
WP_079245952.1\|4654838_4655174_-	hypothetical protein	A0A1C8E986	Bacillus_phage	2.1e-53	97.2
WP_000998745.1\|4655148_4655409_-\|head,tail	phage gp6-like head-tail connector protein	A0A1C8E967	Bacillus_phage	1.3e-39	93.0
WP_079245190.1\|4655412_4656786_-\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	5.3e-151	77.2
WP_042596662.1\|4656787_4657366_-\|head,protease	HK97 family phage prohead protease	A0A2H4J6Z9	uncultured_Caudovirales_phage	4.7e-85	81.5
WP_079245953.1\|4657334_4658540_-\|portal	phage portal protein	A0A1B2APW5	Phage_Wrath	8.8e-219	95.5
WP_079245954.1\|4658628_4658907_+	hypothetical protein	D2IZW1	Enterococcus_phage	1.3e-27	60.9
WP_079245955.1\|4658903_4659107_-	hypothetical protein	NA	NA	NA	NA
WP_079245956.1\|4659121_4660846_-\|terminase	terminase large subunit	A0A1B2AQ28	Phage_Wrath	0.0e+00	96.7
WP_016084503.1\|4660842_4661277_-	hypothetical protein	A0A1B2APW6	Phage_Wrath	3.5e-69	95.1
WP_079245957.1\|4661396_4661762_-	HNH endonuclease	A0A2H4JA38	uncultured_Caudovirales_phage	2.0e-41	63.6
WP_079245958.1\|4661758_4662040_-	hypothetical protein	A0A1C8EAA0	Bacillus_phage	1.7e-27	69.5
WP_079245959.1\|4662036_4662258_-	hypothetical protein	NA	NA	NA	NA
WP_079245960.1\|4662396_4662783_-	hypothetical protein	A0A2H4JFW6	uncultured_Caudovirales_phage	1.3e-46	72.8
WP_079245961.1\|4663169_4665032_-	DNA primase	A0A1B1P7L5	Bacillus_phage	0.0e+00	96.8
WP_079245962.1\|4665108_4665912_+	hypothetical protein	NA	NA	NA	NA
WP_079245963.1\|4665945_4667634_-	hypothetical protein	A0A1B1P7M5	Bacillus_phage	0.0e+00	98.4
WP_079245964.1\|4667851_4668343_-	DUF669 domain-containing protein	A0A1B1P7N3	Bacillus_phage	1.4e-82	89.0
WP_079245965.1\|4668342_4668684_-	organic solvent tolerance protein OstA	A0A1B1P7N6	Bacillus_phage	1.0e-55	99.1
WP_079245966.1\|4668686_4670621_-	AAA family ATPase	A0A1B1P7N0	Bacillus_phage	0.0e+00	96.1
WP_079245967.1\|4670793_4671072_-	nuclease	A0A1B1P7M6	Bacillus_phage	1.5e-49	98.9
WP_079245968.1\|4671064_4671268_-	hypothetical protein	A0A1B1P7L2	Bacillus_phage	3.5e-27	97.0
WP_079245969.1\|4671279_4671594_-	hypothetical protein	A0A1B1P7L0	Bacillus_phage	2.9e-41	81.7
WP_001262629.1\|4671590_4671788_-	hypothetical protein	A0A1B1P7L7	Bacillus_phage	5.6e-30	100.0
WP_079245970.1\|4671788_4673012_-	DEAD/DEAH box helicase	A0A1B1P7L4	Bacillus_phage	4.4e-234	98.3
WP_079245971.1\|4673056_4673707_-	sigma-70 family RNA polymerase sigma factor	H0USU1	Bacillus_phage	2.9e-91	77.7
WP_079245972.1\|4673727_4674078_-	hypothetical protein	A0A2H4JBP9	uncultured_Caudovirales_phage	9.2e-52	88.8
WP_079245973.1\|4674882_4675134_-	transcriptional regulator	A0A2H4JEY2	uncultured_Caudovirales_phage	6.2e-34	86.9
WP_079245974.1\|4675304_4675991_+	helix-turn-helix transcriptional regulator	A0A2H4JDE4	uncultured_Caudovirales_phage	8.2e-121	94.7
WP_060851674.1\|4676074_4677469_+	recombinase family protein	A0A2H4JFH9	uncultured_Caudovirales_phage	3.9e-218	81.7
WP_001013397.1\|4677472_4677871_-	DNA repair protein RadC	NA	NA	NA	NA
WP_000720491.1\|4677917_4678493_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_079245975.1\|4678725_4679676_-	stage II sporulation protein B	NA	NA	NA	NA
WP_017763622.1\|4679840_4681142_-	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_079245976.1\|4681235_4683881_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	4.2e-165	43.0
WP_000350652.1\|4684364_4685390_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_003256548.1\|4685456_4686458_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_000712938.1\|4686538_4687825_-	glutamate-1-semialdehyde 2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	1.7e-05	34.1
WP_001087080.1\|4687824_4688814_-	porphobilinogen synthase	NA	NA	NA	NA
WP_000992324.1\|4688834_4689587_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_001226403.1\|4689589_4690519_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_000009002.1\|4690534_4691368_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_079245977.1\|4691385_4692720_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_000133913.1\|4693136_4693589_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000359773.1\|4693591_4694008_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_000869118.1\|4694042_4694639_-	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
WP_000097281.1\|4694635_4696966_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	7.3e-177	43.7
WP_000119171.1\|4697148_4698819_-\|protease	ATP-dependent protease LonB	E3T4F6	Cafeteria_roenbergensis_virus	8.7e-15	33.5
WP_000472289.1\|4698925_4700185_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.0e-148	66.3

DBSCAN-SWA_12

4759454 : 4767142

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221121.1\|4759454_4760378_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.6e-45	43.5
WP_079245996.1\|4760503_4761439_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.8e-23	26.3
WP_000018046.1\|4761440_4762133_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	6.8e-06	26.9
WP_001014310.1\|4762477_4762672_+	YwbE family protein	NA	NA	NA	NA
WP_001255945.1\|4762711_4763911_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	6.1e-71	41.0
WP_000587818.1\|4764205_4764529_+	heme oxygenase	NA	NA	NA	NA
WP_002162479.1\|4764601_4765366_-	class B sortase	NA	NA	NA	NA
WP_000403765.1\|4765398_4766169_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.7e-13	28.6
WP_001036829.1\|4766158_4767142_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.9e-17	27.2

DBSCAN-SWA_13

5165492 : 5244178

100

Bacillus_phage(39.29%)

protease,coat,portal,tail,head,holin,terminase,capsid,integrase

attL 5187521:5187537|attR 5228010:5228026

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000614219.1\|5165492_5166494_-\|coat	spore coat protein CotS	NA	NA	NA	NA
WP_000665102.1\|5166614_5167106_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	4.6e-41	54.5
WP_000351144.1\|5167129_5167609_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_017763721.1\|5167770_5168874_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_017763722.1\|5168818_5170165_+	hypothetical protein	A0A172Q0Y1	Acinetobacter_phage	3.6e-11	27.0
WP_000241496.1\|5170170_5171283_+\|protease	cysteine protease StiP family protein	NA	NA	NA	NA
WP_000575387.1\|5171279_5172095_+	HAD hydrolase family protein	NA	NA	NA	NA
WP_000683427.1\|5172647_5173229_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_000276470.1\|5173268_5174033_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_000503340.1\|5174142_5174775_-	transcriptional regulator	NA	NA	NA	NA
WP_000274010.1\|5174855_5175296_-	DUF86 domain-containing protein	NA	NA	NA	NA
WP_000439090.1\|5175443_5176415_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000392611.1\|5176432_5176699_+	DUF3055 domain-containing protein	NA	NA	NA	NA
WP_017763725.1\|5177072_5177570_+	hypothetical protein	NA	NA	NA	NA
WP_000435946.1\|5177615_5177924_-	YutD family protein	NA	NA	NA	NA
WP_000744128.1\|5178042_5178621_+	hypothetical protein	NA	NA	NA	NA
WP_000178111.1\|5178648_5179383_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_025989102.1\|5179483_5180299_+\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_000738177.1\|5180323_5180767_-	hypothetical protein	NA	NA	NA	NA
WP_000721045.1\|5180900_5181455_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_000272753.1\|5181529_5182009_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_000166367.1\|5182029_5182926_-	lipoyl synthase	NA	NA	NA	NA
WP_000944693.1\|5183115_5184099_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_000021796.1\|5184171_5184903_-	sporulation protein YunB	NA	NA	NA	NA
WP_000248473.1\|5184957_5185260_-	DUF1805 domain-containing protein	NA	NA	NA	NA
WP_079246078.1\|5185325_5186717_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
5187521:5187537	attL	NA	NA	NA	NA
WP_079246079.1\|5187860_5188694_+	cytosolic protein	A0A2H4J6G7	uncultured_Caudovirales_phage	9.3e-127	84.8
WP_079246080.1\|5188711_5189002_-	hypothetical protein	A0A1C8E992	Bacillus_phage	6.1e-41	89.7
WP_001016120.1\|5189026_5189245_-	hypothetical protein	A0A2H4JC50	uncultured_Caudovirales_phage	1.6e-30	93.1
WP_079246081.1\|5189384_5189951_+	hypothetical protein	A6XML2	Bacillus_virus	1.8e-25	45.0
WP_079246082.1\|5190129_5190348_-	hypothetical protein	A0A2H4JBB8	uncultured_Caudovirales_phage	6.0e-17	75.4
WP_079246083.1\|5190347_5191463_-	tetratricopeptide repeat protein	A0A2H4J8G3	uncultured_Caudovirales_phage	3.1e-109	55.1
WP_079246084.1\|5191666_5192599_-	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	6.7e-158	83.6
WP_000373898.1\|5192598_5193024_-\|holin	phage holin family protein	A0A0S2MVC4	Bacillus_phage	2.6e-72	100.0
WP_048549194.1\|5193061_5193436_-	hypothetical protein	A0A0S2MVE0	Bacillus_phage	6.4e-67	100.0
WP_079246085.1\|5193451_5199010_-	hypothetical protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	59.4
WP_079246086.1\|5199006_5200476_-\|tail	phage tail protein	A0A0S2MV63	Bacillus_phage	1.6e-230	78.5
WP_145953858.1\|5200517_5202932_-	hypothetical protein	A0A2H4JC82	uncultured_Caudovirales_phage	2.1e-41	42.8
WP_000415931.1\|5204416_5204779_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	1.4e-42	71.7
WP_001004918.1\|5204785_5205379_-\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	9.7e-102	91.8
WP_079246088.1\|5205379_5205709_-	hypothetical protein	A0A2H4JAG4	uncultured_Caudovirales_phage	5.4e-54	94.5
WP_079246089.1\|5205705_5206050_-	HK97 gp10 family phage protein	A0A2H4JAH8	uncultured_Caudovirales_phage	1.7e-45	79.6
WP_079246090.1\|5206051_5206402_-\|head	phage head closure protein	D2XR20	Bacillus_phage	2.2e-53	88.8
WP_079246091.1\|5206403_5206697_-	hypothetical protein	A0A2H4JG04	uncultured_Caudovirales_phage	2.8e-38	79.4
WP_079246092.1\|5206702_5207860_-\|capsid	phage major capsid protein	A0A2H4JHU0	uncultured_Caudovirales_phage	4.7e-201	91.7
WP_079246334.1\|5207863_5208607_-\|protease	Clp protease ClpP	D2XR17	Bacillus_phage	2.6e-112	85.4
WP_016123349.1\|5208606_5209776_-\|portal	phage portal protein	A0A2H4JBZ5	uncultured_Caudovirales_phage	3.7e-206	95.0
WP_079246093.1\|5211348_5211660_-\|terminase	terminase	D2XR14	Bacillus_phage	5.5e-40	86.3
WP_000253626.1\|5211765_5212263_-	endonuclease	A0A2H4J2Q3	uncultured_Caudovirales_phage	9.8e-31	43.9
WP_079246094.1\|5212256_5212592_-	HNH endonuclease	D2XR61	Bacillus_phage	1.6e-53	91.0
WP_079246095.1\|5212557_5212932_-	hypothetical protein	NA	NA	NA	NA
WP_000378697.1\|5212922_5213180_-	hypothetical protein	NA	NA	NA	NA
WP_001177575.1\|5213186_5213396_-	hypothetical protein	NA	NA	NA	NA
WP_079246096.1\|5213464_5213899_-	hypothetical protein	Q2I8B8	Bacillus_phage	4.1e-17	59.4
WP_079246097.1\|5213904_5214108_-	hypothetical protein	NA	NA	NA	NA
WP_079246098.1\|5214121_5214346_-	hypothetical protein	NA	NA	NA	NA
WP_079246335.1\|5214525_5214708_+	type II toxin-antitoxin system HicA family toxin	A0A0U4KLG1	Pseudomonas_phage	2.7e-15	65.5
WP_000711194.1\|5214759_5215179_+	HicB family protein	A0A2H4J4X8	uncultured_Caudovirales_phage	4.5e-61	79.9
WP_079246336.1\|5215562_5215964_-	hypothetical protein	A0A1C8E9D1	Bacillus_phage	6.8e-67	98.5
WP_000074644.1\|5216001_5216328_-	hypothetical protein	A0A1C8E9C1	Bacillus_phage	2.8e-58	99.1
WP_079246099.1\|5216324_5216852_-	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	7.0e-96	97.7
WP_079246100.1\|5216880_5217213_-	hypothetical protein	NA	NA	NA	NA
WP_053512893.1\|5217259_5217955_-	hypothetical protein	A0A1I9S6E4	Bacillus_phage	3.5e-111	79.3
WP_001093039.1\|5218037_5218829_-	prohibitin family protein	A0A1C8E9A9	Bacillus_phage	6.8e-143	100.0
WP_079246101.1\|5218975_5219266_-	hypothetical protein	A0A1C8EA94	Bacillus_phage	2.2e-51	96.9
WP_079246102.1\|5219324_5219759_-	hypothetical protein	A0A2H4JBD8	uncultured_Caudovirales_phage	2.0e-72	91.0
WP_079246103.1\|5219797_5220358_-	hypothetical protein	A0A1C8E9B1	Bacillus_phage	4.1e-102	96.8
WP_079246104.1\|5220390_5220984_-	hypothetical protein	A0A1C8E9A7	Bacillus_phage	4.1e-84	96.8
WP_079246105.1\|5221007_5221238_-	hypothetical protein	A0A1C8E9C2	Bacillus_phage	1.4e-32	97.4
WP_079246106.1\|5221230_5221710_-	hypothetical protein	A0A2H4J396	uncultured_Caudovirales_phage	5.3e-82	94.3
WP_079246107.1\|5221721_5222642_-	DnaD domain protein	A0A2H4J394	uncultured_Caudovirales_phage	2.6e-130	94.5
WP_079246108.1\|5222737_5223076_-	hypothetical protein	A0A2H4J6H7	uncultured_Caudovirales_phage	2.0e-51	96.4
WP_079246109.1\|5223008_5223224_-	hypothetical protein	A0A2H4J3B2	uncultured_Caudovirales_phage	5.1e-29	91.5
WP_042597301.1\|5223223_5223937_-	hypothetical protein	A0A1C8EA84	Bacillus_phage	3.0e-126	97.9
WP_000453492.1\|5223955_5224390_-	hypothetical protein	A0A0S2MVA8	Bacillus_phage	3.1e-73	98.6
WP_079246110.1\|5224416_5224605_-	hypothetical protein	A0A2H4J4V8	uncultured_Caudovirales_phage	5.9e-13	62.9
WP_079246111.1\|5224616_5225375_-	phage regulatory protein	A0A2H4JBC7	uncultured_Caudovirales_phage	1.8e-108	79.4
WP_016099149.1\|5225553_5225742_-	hypothetical protein	R9TQ08	Paenibacillus_phage	1.4e-17	67.2
WP_079246112.1\|5225769_5226015_-	helix-turn-helix transcriptional regulator	A0A1B2APZ4	Phage_Wrath	4.1e-22	74.7
WP_016099151.1\|5226179_5226806_+	helix-turn-helix domain-containing protein	A0A1B2APZ3	Phage_Wrath	5.5e-71	63.2
WP_016099152.1\|5226892_5227936_+\|integrase	site-specific integrase	A0A1J0MF14	Staphylococcus_phage	3.8e-93	47.3
WP_079246113.1\|5228002_5229400_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
5228010:5228026	attR	NA	NA	NA	NA
WP_000009525.1\|5229448_5229880_-	iron-sulfur cluster assembly scaffold protein SufU	A0A0K1LS29	Mycobacterium_phage	1.6e-13	36.8
WP_001020767.1\|5229869_5231090_-	cysteine desulfurase SufS	Q2XUY6	environmental_halophage	2.3e-118	47.6
WP_000152177.1\|5231089_5232382_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000929162.1\|5232397_5233183_-	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	7.0e-07	27.1
WP_079246114.1\|5233421_5234228_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000735090.1\|5234299_5235112_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000359401.1\|5235135_5235801_-	ABC transporter permease	NA	NA	NA	NA
WP_017763726.1\|5235793_5236819_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.5e-29	37.6
WP_001242143.1\|5237232_5237577_-	hypothetical protein	NA	NA	NA	NA
WP_000568179.1\|5237729_5238029_-	thioredoxin family protein	NA	NA	NA	NA
WP_000640870.1\|5238041_5238386_-	hypothetical protein	NA	NA	NA	NA
WP_000026896.1\|5239116_5239500_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_000218968.1\|5239541_5239907_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.1e-21	48.6
WP_000826875.1\|5240318_5240846_-	hypothetical protein	NA	NA	NA	NA
WP_000713769.1\|5240990_5241638_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000666176.1\|5241697_5242711_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_106081637.1\|5242733_5243903_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_001002987.1\|5243929_5244178_-\|coat	spore coat protein	NA	NA	NA	NA

DBSCAN-SWA_14

5344494 : 5439122

105

Bacillus_phage(50.91%)

protease,portal,tail,transposase,head,holin,terminase,capsid,integrase

attL 5383350:5383370|attR 5422641:5422661

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079246133.1\|5344494_5347185_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_079246134.1\|5347181_5348474_-	TniQ family protein	NA	NA	NA	NA
WP_079246135.1\|5348874_5349858_-	hypothetical protein	NA	NA	NA	NA
WP_079246136.1\|5349850_5352001_-	hypothetical protein	NA	NA	NA	NA
WP_159451462.1\|5351981_5353322_-	hypothetical protein	NA	NA	NA	NA
WP_079246138.1\|5353840_5354677_-	hypothetical protein	NA	NA	NA	NA
WP_159451463.1\|5354773_5355634_+	hypothetical protein	V5URE9	Synechococcus_phage	9.9e-23	29.5
WP_079246140.1\|5356539_5357031_-	DUF4652 domain-containing protein	NA	NA	NA	NA
WP_079246142.1\|5357703_5358450_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_079246143.1\|5358483_5360667_-	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	1.9e-49	29.0
WP_079246144.1\|5360903_5361086_+	hypothetical protein	NA	NA	NA	NA
WP_145953845.1\|5361305_5362298_-	DUF4046 domain-containing protein	NA	NA	NA	NA
WP_000412934.1\|5362518_5364012_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.1e-82	40.4
WP_079246145.1\|5365104_5365284_+	hypothetical protein	NA	NA	NA	NA
WP_079246146.1\|5365983_5366199_-	hypothetical protein	NA	NA	NA	NA
WP_001123917.1\|5367307_5367775_-	SsrA-binding protein	W5RAM5	Staphylococcus_phage	7.0e-47	62.5
WP_079246149.1\|5368146_5370585_-	ribonuclease R	Q0GXV6	Lactococcus_phage	1.7e-91	40.6
WP_000761976.1\|5370727_5371468_-	carboxylesterase	NA	NA	NA	NA
WP_000557266.1\|5371628_5371862_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_000078304.1\|5371956_5372649_-	LrgB family protein	NA	NA	NA	NA
WP_000673222.1\|5372645_5373014_-\|holin	CidA/LrgA family holin-like protein	NA	NA	NA	NA
WP_079246150.1\|5373366_5374317_+	nucleoside hydrolase	NA	NA	NA	NA
WP_000103951.1\|5374367_5375663_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.1e-182	75.4
WP_001231141.1\|5375693_5377223_-	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_001231042.1\|5377219_5377975_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_001036332.1\|5378007_5379192_-	phosphoglycerate kinase	NA	NA	NA	NA
WP_000161234.1\|5379331_5380336_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_001258185.1\|5380362_5381391_-	gapA transcriptional regulator CggR	NA	NA	NA	NA
WP_000869737.1\|5381527_5381773_-	glutaredoxin family protein	NA	NA	NA	NA
WP_000647951.1\|5381782_5383090_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
5383350:5383370	attL	NA	NA	NA	NA
WP_079246151.1\|5383653_5384634_+	cytosolic protein	A0A0S2MVF4	Bacillus_phage	1.0e-140	79.5
WP_044797908.1\|5384691_5385132_+	hypothetical protein	NA	NA	NA	NA
WP_044797907.1\|5385274_5386378_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	6.9e-186	92.5
WP_079246152.1\|5386933_5387869_-	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	1.5e-160	84.2
WP_079246153.1\|5387868_5388294_-\|holin	phage holin family protein	A0A0S2MVC4	Bacillus_phage	1.4e-70	98.6
WP_079246154.1\|5388334_5388700_-	hypothetical protein	A0A0S2MVE0	Bacillus_phage	3.1e-34	57.4
WP_079246155.1\|5388716_5393561_-	hypothetical protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	83.4
WP_079246156.1\|5393557_5395027_-\|tail	phage tail protein	A0A0S2MV63	Bacillus_phage	2.0e-236	80.0
WP_145953859.1\|5395068_5397462_-	hypothetical protein	A0A2H4JC82	uncultured_Caudovirales_phage	1.5e-39	41.8
WP_144489603.1\|5397495_5397609_+	TRASH domain-containing protein	NA	NA	NA	NA
WP_038413229.1\|5398943_5399306_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	1.2e-41	69.2
WP_001004921.1\|5399312_5399906_-\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	6.7e-103	93.3
WP_079246158.1\|5399906_5400242_-	hypothetical protein	A0A2H4JAG4	uncultured_Caudovirales_phage	2.7e-53	93.6
WP_000997537.1\|5400238_5400583_-	HK97 gp10 family phage protein	A0A2H4JAH8	uncultured_Caudovirales_phage	1.7e-45	80.5
WP_079246159.1\|5400584_5400950_-\|head	phage head closure protein	A0A2H4JGG7	uncultured_Caudovirales_phage	2.2e-56	93.3
WP_000450787.1\|5400951_5401251_-	hypothetical protein	D2XR19	Bacillus_phage	2.1e-41	86.9
WP_079246160.1\|5401256_5402414_-\|capsid	phage major capsid protein	A0A2H4JHU0	uncultured_Caudovirales_phage	7.5e-199	90.6
WP_079246341.1\|5402417_5403161_-\|protease	Clp protease ClpP	D2XR17	Bacillus_phage	2.1e-117	88.3
WP_079246161.1\|5403160_5404306_-\|portal	phage portal protein	A0A2H4JAJ1	uncultured_Caudovirales_phage	2.2e-182	82.4
WP_079246162.1\|5404314_5405982_-\|terminase	terminase large subunit	D2XR15	Bacillus_phage	4.4e-293	87.6
WP_079246093.1\|5405978_5406290_-\|terminase	terminase	D2XR14	Bacillus_phage	5.5e-40	86.3
WP_000253626.1\|5406395_5406893_-	endonuclease	A0A2H4J2Q3	uncultured_Caudovirales_phage	9.8e-31	43.9
WP_079246094.1\|5406886_5407222_-	HNH endonuclease	D2XR61	Bacillus_phage	1.6e-53	91.0
WP_079246095.1\|5407187_5407562_-	hypothetical protein	NA	NA	NA	NA
WP_000378697.1\|5407552_5407810_-	hypothetical protein	NA	NA	NA	NA
WP_001177575.1\|5407816_5408026_-	hypothetical protein	NA	NA	NA	NA
WP_079246096.1\|5408094_5408529_-	hypothetical protein	Q2I8B8	Bacillus_phage	4.1e-17	59.4
WP_079246097.1\|5408534_5408738_-	hypothetical protein	NA	NA	NA	NA
WP_079246098.1\|5408751_5408976_-	hypothetical protein	NA	NA	NA	NA
WP_079246335.1\|5409155_5409338_+	type II toxin-antitoxin system HicA family toxin	A0A0U4KLG1	Pseudomonas_phage	2.7e-15	65.5
WP_000711194.1\|5409389_5409809_+	HicB family protein	A0A2H4J4X8	uncultured_Caudovirales_phage	4.5e-61	79.9
WP_079246336.1\|5410192_5410594_-	hypothetical protein	A0A1C8E9D1	Bacillus_phage	6.8e-67	98.5
WP_000074644.1\|5410631_5410958_-	hypothetical protein	A0A1C8E9C1	Bacillus_phage	2.8e-58	99.1
WP_079246099.1\|5410954_5411482_-	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	7.0e-96	97.7
WP_079246100.1\|5411510_5411843_-	hypothetical protein	NA	NA	NA	NA
WP_053512893.1\|5411889_5412585_-	hypothetical protein	A0A1I9S6E4	Bacillus_phage	3.5e-111	79.3
WP_001093039.1\|5412667_5413459_-	prohibitin family protein	A0A1C8E9A9	Bacillus_phage	6.8e-143	100.0
WP_001268029.1\|5413605_5413896_-	hypothetical protein	A0A1C8EA94	Bacillus_phage	5.5e-50	96.9
WP_001053193.1\|5414002_5414437_-	hypothetical protein	A0A1C8E9B0	Bacillus_phage	1.7e-79	98.6
WP_001245737.1\|5414475_5415033_-	hypothetical protein	A0A1B1P7A6	Bacillus_phage	2.0e-64	70.8
WP_079246163.1\|5415056_5415287_-	hypothetical protein	A0A1C8E9C2	Bacillus_phage	3.3e-34	98.7
WP_079246164.1\|5415279_5415759_-	hypothetical protein	A0A2H4J396	uncultured_Caudovirales_phage	1.2e-81	93.7
WP_079246165.1\|5415770_5416724_-	DnaD domain protein	A0A0S2MVA0	Bacillus_phage	2.2e-148	90.5
WP_079246166.1\|5416817_5417159_-	hypothetical protein	A0A0S2MVH7	Bacillus_phage	2.6e-51	98.2
WP_000355709.1\|5417088_5417304_-	hypothetical protein	A0A1C8E9A6	Bacillus_phage	1.4e-31	98.6
WP_079246167.1\|5417303_5418017_-	hypothetical protein	A0A1C8EA84	Bacillus_phage	1.2e-125	97.0
WP_079246168.1\|5418034_5418469_-	replication terminator protein	A0A0S2MVA8	Bacillus_phage	1.8e-73	98.6
WP_079246169.1\|5418495_5418684_-	hypothetical protein	A0A2H4J4V8	uncultured_Caudovirales_phage	5.0e-12	61.3
WP_001016247.1\|5418695_5419451_-	phage regulatory protein	A0A2H4JBC7	uncultured_Caudovirales_phage	1.9e-110	83.4
WP_000410023.1\|5419804_5420038_-	DUF771 domain-containing protein	Q9MBW7	Lactococcus_phage	5.6e-05	43.5
WP_000216290.1\|5420073_5420304_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002133807.1\|5420468_5420861_+	helix-turn-helix transcriptional regulator	A0A1Q1PVX8	Staphylococcus_phage	3.2e-13	58.5
WP_001037137.1\|5420871_5421339_+	hypothetical protein	NA	NA	NA	NA
WP_000135757.1\|5421369_5422506_+\|integrase	site-specific integrase	A8ATX2	Listeria_phage	6.8e-96	48.0
WP_079246170.1\|5422920_5423127_+	DUF1657 domain-containing protein	NA	NA	NA	NA
5422641:5422661	attR	NA	NA	NA	NA
WP_001228537.1\|5423220_5423706_+	hypothetical protein	NA	NA	NA	NA
WP_000095399.1\|5423735_5424212_+	stage V sporulation protein AC	NA	NA	NA	NA
WP_000938953.1\|5424212_5425229_+	stage V sporulation protein AD	NA	NA	NA	NA
WP_000575919.1\|5425225_5425576_+	stage V sporulation protein AE	NA	NA	NA	NA
WP_000215916.1\|5425588_5425795_+	DUF1657 domain-containing protein	NA	NA	NA	NA
WP_016099273.1\|5425815_5426685_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_001049162.1\|5426926_5427508_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.3e-55	56.5
WP_000250307.1\|5428031_5428280_-	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_000006563.1\|5428303_5429254_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	3.9e-52	38.1
WP_000712185.1\|5429342_5430296_-	YvcK family protein	A1IMD5	Streptococcus_phage	5.8e-64	43.1
WP_079246171.1\|5430299_5431181_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.7e-06	28.2
WP_001190080.1\|5431201_5431660_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_000455196.1\|5431889_5432696_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_001288077.1\|5432861_5433818_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.6e-90	53.9
WP_000517718.1\|5433903_5435415_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_079246172.1\|5435554_5436067_-	acetyltransferase	NA	NA	NA	NA
WP_001222403.1\|5436100_5436751_-	pyrophosphatase PpaX	NA	NA	NA	NA
WP_000924241.1\|5436818_5437631_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_001127251.1\|5437655_5438585_-	HPr(Ser) kinase/phosphatase	NA	NA	NA	NA
WP_001267308.1\|5438741_5439122_-\|holin	phage holin family protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP020003

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

49 : 54547

Bacillus_phage(63.64%)

terminase,tail,integrase,holin,transposase,capsid,portal

attL 273:287|attR 15812:15826

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159451465.1\|49_361_+	hypothetical protein	A0A1B1P8B5	Bacillus_phage	2.8e-12	39.5
273:287	attL	NA	NA	NA	NA
WP_062804543.1\|2049_2580_+	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	4.6e-79	82.4
WP_062804544.1\|2579_2918_+	zinc-finger domain-containing protein	A0A0S2MV86	Bacillus_phage	4.0e-20	46.2
WP_062804545.1\|3063_3564_+	sigma-70 family RNA polymerase sigma factor	A0A0S2MVE1	Bacillus_phage	5.5e-74	84.2
WP_079246348.1\|4036_4261_+	hypothetical protein	NA	NA	NA	NA
WP_000418201.1\|4750_5155_+	helix-turn-helix domain-containing protein	A0A142F1N8	Bacillus_phage	2.1e-07	50.0
WP_000673901.1\|5327_5870_+\|integrase	site-specific integrase	A0A1B0T6D2	Bacillus_phage	1.7e-44	49.7
WP_079246349.1\|5929_6178_+	hypothetical protein	A0A1B1P7C3	Bacillus_phage	2.1e-10	42.2
WP_079246350.1\|6210_6390_+	hypothetical protein	NA	NA	NA	NA
WP_079246351.1\|6411_7260_+\|terminase	terminase	A0A0A8WJN3	Clostridium_phage	8.9e-32	48.2
WP_000072122.1\|7252_8659_+	DEAD/DEAH box helicase family protein	A0A0A8WEW2	Clostridium_phage	2.0e-169	63.7
WP_079246352.1\|8728_10207_+\|portal	phage portal protein	A0A222YY66	Streptomyces_phage	1.0e-46	27.4
WP_079246353.1\|10320_10839_+\|capsid	minor capsid protein	Q1WDG7	Streptomyces_phage	1.1e-08	34.4
WP_079246354.1\|10952_12155_+	hypothetical protein	A0A1B1P7E4	Bacillus_phage	5.2e-54	39.8
WP_000537552.1\|12175_13165_+	hypothetical protein	H7BVA6	unidentified_phage	7.3e-70	44.8
WP_079246355.1\|13335_13500_+	hypothetical protein	NA	NA	NA	NA
WP_079246356.1\|13499_14036_+	hypothetical protein	NA	NA	NA	NA
WP_001004649.1\|14032_14404_+	hypothetical protein	NA	NA	NA	NA
WP_079246357.1\|14410_14821_+	hypothetical protein	NA	NA	NA	NA
WP_079246358.1\|14824_15247_+	hypothetical protein	NA	NA	NA	NA
WP_079246359.1\|15259_15862_+	hypothetical protein	D3W0E4	Lactococcus_phage	1.6e-14	27.4
15812:15826	attR	NA	NA	NA	NA
WP_079246360.1\|15919_16438_+	hypothetical protein	NA	NA	NA	NA
WP_079246361.1\|16401_16824_+	hypothetical protein	NA	NA	NA	NA
WP_079246362.1\|16856_19880_+\|tail	phage tail tape measure protein	A0A1B1P7P9	Bacillus_phage	5.7e-89	54.9
WP_079246363.1\|19876_20560_+	hypothetical protein	NA	NA	NA	NA
WP_079246364.1\|20556_22101_+	hypothetical protein	NA	NA	NA	NA
WP_016512900.1\|22111_22495_+	hypothetical protein	NA	NA	NA	NA
WP_079246365.1\|22539_22914_+	Low copy number virion structural protein	A0A0K2CPR2	Brevibacillus_phage	3.3e-15	36.9
WP_079246366.1\|22926_23304_+	Low copy number virion structural protein	A0A0K2CPN7	Brevibacillus_phage	2.8e-22	38.3
WP_079246367.1\|23317_24661_+	hypothetical protein	A0A0K2CP42	Brevibacillus_phage	2.3e-74	34.8
WP_000264171.1\|24675_26412_+	hypothetical protein	A0A0K2CNY7	Brevibacillus_phage	4.8e-125	43.6
WP_079246368.1\|26433_28947_+	hypothetical protein	NA	NA	NA	NA
WP_079246369.1\|28959_30483_+	hypothetical protein	NA	NA	NA	NA
WP_079246370.1\|30495_30876_+	hypothetical protein	G3MAB0	Bacillus_virus	1.0e-11	33.3
WP_079246371.1\|30891_31845_+	hypothetical protein	NA	NA	NA	NA
WP_079245061.1\|32377_33574_-\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	5.6e-24	25.9
WP_000439586.1\|33869_34367_+\|holin	holin	A0A0M4R5G6	Bacillus_phage	1.2e-25	42.8
WP_079246373.1\|34446_35505_+	SH3 domain-containing protein	A0A1B1P7Q1	Bacillus_phage	3.2e-148	74.3
WP_061663780.1\|35661_36777_+	tetratricopeptide repeat protein	A0A2H4J8G3	uncultured_Caudovirales_phage	1.2e-105	54.1
WP_000734385.1\|36776_37022_+	hypothetical protein	A0A2H4JBB8	uncultured_Caudovirales_phage	6.7e-17	75.4
WP_061663782.1\|37075_37312_-	hypothetical protein	A0A1B1P789	Bacillus_phage	6.5e-17	50.6
WP_061663784.1\|37406_37646_-	hypothetical protein	NA	NA	NA	NA
WP_061663786.1\|37635_38646_-	plasmid segregation protein ParM	A0A2H4IZP5	uncultured_Caudovirales_phage	2.7e-27	27.5
WP_159451466.1\|38851_39910_-	RES domain-containing protein	NA	NA	NA	NA
WP_061663789.1\|40074_40605_-	DUF3967 domain-containing protein	A0A1Z1LZN4	Bacillus_phage	6.8e-14	38.9
WP_079246374.1\|41062_41437_-	hypothetical protein	NA	NA	NA	NA
WP_001246650.1\|41579_41858_-	hypothetical protein	A0A0S2MVK9	Bacillus_phage	8.7e-37	79.1
WP_079246376.1\|42304_42892_-	hypothetical protein	NA	NA	NA	NA
WP_079246377.1\|42927_43971_-	helix-turn-helix domain-containing protein	A0A0A7AQV7	Bacillus_phage	6.0e-06	39.6
WP_079246378.1\|44945_45476_-	ribonuclease	NA	NA	NA	NA
WP_079246379.1\|45949_46294_-	helix-turn-helix transcriptional regulator	D2XR39	Bacillus_phage	9.8e-06	39.8
WP_159451467.1\|46578_46923_-	helix-turn-helix domain-containing protein	A0A0A7AR52	Bacillus_phage	2.2e-13	40.6
WP_079246381.1\|47146_47353_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_079246382.1\|47424_47613_+	hypothetical protein	NA	NA	NA	NA
WP_079246383.1\|47618_48311_+	Rha family transcriptional regulator	A0A0U4IS08	Exiguobacterium_phage	7.0e-35	40.5
WP_079246384.1\|48333_48696_+	replication terminator protein	A0A0S2MVA8	Bacillus_phage	2.2e-40	66.9
WP_061663800.1\|48718_49066_+	hypothetical protein	A0A0S2MVM3	Bacillus_phage	2.1e-24	56.5
WP_000348870.1\|49254_49755_+	hypothetical protein	A0A0A7AQW2	Bacillus_phage	1.3e-62	73.0
WP_000139415.1\|49723_50140_+	hypothetical protein	A0A0S2MVI0	Bacillus_phage	6.9e-46	65.0
WP_079246385.1\|50142_50610_+	hypothetical protein	A0A0S2MVB7	Bacillus_phage	3.3e-36	47.7
WP_079246386.1\|50816_51098_+	hypothetical protein	A0A0S2MVE2	Bacillus_phage	3.1e-18	55.2
WP_079246387.1\|51094_51544_+	hypothetical protein	A0A0S2MVJ1	Bacillus_phage	3.7e-69	80.0
WP_062804540.1\|51540_52122_+	dUTPase	A0A0S2MVD0	Bacillus_phage	4.1e-97	88.1
WP_079246388.1\|52134_52692_+	hypothetical protein	A0A0S2MVC3	Bacillus_phage	3.7e-103	95.7
WP_079246389.1\|52749_53088_+	hypothetical protein	NA	NA	NA	NA
WP_079246390.1\|53084_53303_+	DUF3797 domain-containing protein	Q24LE0	Clostridium_phage	3.1e-05	41.2
WP_079246391.1\|53472_53823_+	hypothetical protein	NA	NA	NA	NA
WP_061885268.1\|53851_54547_+	hypothetical protein	A0A1I9S6E4	Bacillus_phage	6.4e-113	82.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP020004

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7 : 49719

Bacillus_phage(90.0%)

integrase,tail,holin,terminase,portal

attL 1566:1580|attR 48503:48517

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159451468.1\|7_211_-	hypothetical protein	A0A1B1P8C8	Bacillus_phage	3.4e-14	55.2
WP_079246439.1\|444_669_-	hypothetical protein	NA	NA	NA	NA
WP_159451469.1\|715_886_-	hypothetical protein	NA	NA	NA	NA
WP_079246395.1\|1153_1891_-	hypothetical protein	A0A2H4J6H9	uncultured_Caudovirales_phage	1.0e-55	47.4
1566:1580	attL	NA	NA	NA	NA
WP_000661411.1\|1937_2165_-	hypothetical protein	A0A218KCK2	Bacillus_phage	6.9e-24	65.3
WP_000654659.1\|2161_2449_-	hypothetical protein	G9J1X9	Bacillus_phage	8.1e-38	79.6
WP_079246396.1\|2520_3030_-	hypothetical protein	A0A1B1P7A6	Bacillus_phage	3.0e-83	88.8
WP_079246397.1\|3165_3939_-	hypothetical protein	A0A1B1P796	Bacillus_phage	3.0e-95	64.1
WP_079246398.1\|3956_4331_-	cell division protein SepF	A0A1B1P7A1	Bacillus_phage	2.5e-47	73.4
WP_079246399.1\|4358_4775_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A1B1P791	Bacillus_phage	1.3e-15	71.0
WP_079246400.1\|4835_5345_-	hypothetical protein	A0A1B1P794	Bacillus_phage	6.6e-59	69.4
WP_079246401.1\|5356_5884_-	Holliday junction resolvase RecU	A0A1B1P798	Bacillus_phage	1.3e-86	86.9
WP_159451470.1\|6056_6194_-	hypothetical protein	A0A1B1P797	Bacillus_phage	3.7e-09	68.9
WP_043935989.1\|6245_6446_-	helix-turn-helix transcriptional regulator	A0A1B1P7A4	Bacillus_phage	1.9e-09	51.5
WP_079246402.1\|6638_7073_+	helix-turn-helix transcriptional regulator	A0A1B1P7A0	Bacillus_phage	1.8e-33	54.9
WP_159451471.1\|7092_7254_-	hypothetical protein	NA	NA	NA	NA
WP_156137705.1\|7376_7526_-	hypothetical protein	NA	NA	NA	NA
WP_079246403.1\|7622_8825_-	hypothetical protein	A0A1B1P786	Bacillus_phage	2.1e-79	42.3
WP_043935992.1\|8953_9193_+	hypothetical protein	A0A1B1P790	Bacillus_phage	7.7e-26	78.5
WP_079246404.1\|11514_11793_+	YccF domain-containing protein	NA	NA	NA	NA
WP_079246440.1\|12127_12679_+	hypothetical protein	A0A1B1P785	Bacillus_phage	1.7e-44	66.3
WP_079246405.1\|12768_13731_+\|integrase	site-specific integrase	A0A1B1P793	Bacillus_phage	6.7e-137	74.1
WP_162494740.1\|13895_15137_+	ParM/StbA family protein	NA	NA	NA	NA
WP_079246406.1\|15149_15497_+	hypothetical protein	NA	NA	NA	NA
WP_079246407.1\|15586_15826_+	hypothetical protein	A0A1B1P789	Bacillus_phage	8.0e-31	81.0
WP_079246408.1\|15841_16381_+	hypothetical protein	A0A1B1P777	Bacillus_phage	9.1e-83	85.5
WP_079246409.1\|16423_16612_+	hypothetical protein	NA	NA	NA	NA
WP_079246410.1\|16823_17198_+	hypothetical protein	D2XQ01	Bacillus_virus	2.4e-29	53.2
WP_000540681.1\|17400_18231_-	N-acetylmuramoyl-L-alanine amidase	A0A0S2GLD4	Bacillus_phage	2.8e-131	79.3
WP_000810821.1\|18308_18518_-	hypothetical protein	NA	NA	NA	NA
WP_000375145.1\|18498_19014_-\|holin	holin	A0A0M4R5G6	Bacillus_phage	1.8e-27	45.6
WP_079246411.1\|19050_19428_-	hypothetical protein	A0A0S2MVE0	Bacillus_phage	7.1e-42	64.8
WP_079246412.1\|19444_24607_-	hypothetical protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	56.3
WP_079246413.1\|24603_26106_-\|tail	phage tail protein	A0A2H4JC38	uncultured_Caudovirales_phage	1.8e-205	67.7
WP_079246414.1\|26110_31138_-\|tail	phage tail tape measure protein	A0A1B1P7S6	Bacillus_phage	1.9e-267	63.1
WP_000830810.1\|31177_31468_-	hypothetical protein	NA	NA	NA	NA
WP_079246415.1\|31530_32025_-	hypothetical protein	A0A1B1P7E5	Bacillus_phage	1.2e-28	44.1
WP_079246416.1\|32057_32870_-	hypothetical protein	A0A1B1P7D9	Bacillus_phage	7.0e-103	71.1
WP_050822267.1\|32869_33118_-	hypothetical protein	A0A1B1P7E7	Bacillus_phage	3.0e-20	59.8
WP_079246417.1\|33132_33483_-	hypothetical protein	A0A1B1P7D3	Bacillus_phage	1.5e-49	75.9
WP_079246418.1\|33493_33907_-	hypothetical protein	A0A1B1P7D0	Bacillus_phage	3.0e-49	71.5
WP_079246419.1\|33906_34281_-	hypothetical protein	A0A1B1P7D8	Bacillus_phage	1.4e-34	57.9
WP_079246420.1\|34283_34700_-	DUF3199 family protein	A0A1B1P7D6	Bacillus_phage	4.0e-38	58.7
WP_079246421.1\|34705_35029_-	hypothetical protein	A0A1B1P7E2	Bacillus_phage	7.7e-29	63.2
WP_079246422.1\|35040_35976_-	hypothetical protein	A0A1B1P7E3	Bacillus_phage	5.5e-144	85.1
WP_079246423.1\|36003_37200_-	hypothetical protein	A0A1B1P7E4	Bacillus_phage	2.1e-156	74.7
WP_079246425.1\|37635_38556_-	hypothetical protein	A0A1B1P7D7	Bacillus_phage	1.5e-72	49.2
WP_079246426.1\|38571_40098_-\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	2.0e-215	71.5
WP_079246427.1\|40114_41578_-\|terminase	terminase B	A0A1B1P7D5	Bacillus_phage	2.1e-243	83.8
WP_079246428.1\|41584_42100_-	hypothetical protein	NA	NA	NA	NA
WP_079246429.1\|42253_43090_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1P7C7	Bacillus_phage	5.1e-141	88.8
WP_079246430.1\|43094_44036_-	hypothetical protein	A0A1B1P7C9	Bacillus_phage	5.6e-104	74.5
WP_079246431.1\|44095_44329_-	hypothetical protein	NA	NA	NA	NA
WP_079246442.1\|44342_44483_-	BC1881 family protein	NA	NA	NA	NA
WP_079246432.1\|44615_44849_-	hypothetical protein	A0A1B1P7D4	Bacillus_phage	1.3e-25	79.2
WP_079246433.1\|44986_46207_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	1.9e-115	52.0
WP_050822249.1\|46226_46460_-	hypothetical protein	H0USW0	Bacillus_phage	5.4e-16	52.5
WP_079246434.1\|47382_47889_-	ArpU family transcriptional regulator	A0A1B1P7B2	Bacillus_phage	1.6e-68	83.6
WP_145953862.1\|48100_48343_-	hypothetical protein	A0A1B1P7B9	Bacillus_phage	1.0e-17	58.2
WP_000210444.1\|48407_48533_-	DUF3983 domain-containing protein	NA	NA	NA	NA
48503:48517	attR	NA	NA	NA	NA
WP_159451472.1\|48575_48752_-	hypothetical protein	A0A0A7AR63	Bacillus_phage	1.9e-21	86.2
WP_079246435.1\|48785_49190_-	hypothetical protein	W8EIC5	Pseudomonas_phage	3.3e-21	45.3
WP_079246436.1\|49189_49447_-	hypothetical protein	A0A0A0RSN4	Bacillus_phage	9.6e-06	35.4
WP_079246437.1\|49485_49719_-	hypothetical protein	A0A1B1P7A2	Bacillus_phage	8.9e-11	61.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020005

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP020002

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP020003

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP020004

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection