CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018786	Chryseobacterium indologenes strain AA5 chromosome, complete genome	4 crisprs	cas3,PD-DExK,WYL,DEDDh,csa3	0	1	5	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018786_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018786_1

279112-279187

Orphan

Consensus_repeat	Method
TATTTTTATAATCAACATAAAAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018786_1

>merge|NZ_CP018786|1|279112-279187|CRISPRCasFinder
TATTTTTATAATCAACATAAAAATTAGCATCGTTAATGGGAGAAAATATATTATTTTTAAAATCAACATAAAAATT

>NZ_CP018786|1|1|279112-279187|CRISPRCasFinder
TATTTTTATAATCAACATAAAAATT	AGCATCGTTAATGGGAGAAAATATAT
TATTTTTAAAATCAACATAAAAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018786.1\|WP_079240180.1\|266261_266699_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_034691375.1\|290652_291072_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_CP018786.1\|WP_079243827.1\|283035_287397_+\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|226220
NZ_CP018786.1\|WP_079240191.1\|289738_290635_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_CP018786.1\|WP_079240194.1\|293934_294297_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240190.1\|288840_289722_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226304
NZ_CP018786.1\|WP_079240177.1\|262679_263555_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_CP018786.1\|WP_079240183.1\|270549_272043_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|185760
NZ_CP018786.1\|WP_079243828.1\|287479_288709_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP018786.1\|WP_167595377.1\|280863_281331_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240189.1\|282564_282888_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240181.1\|266762_267170_-\|3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|376496
NZ_CP018786.1\|WP_079240182.1\|267597_270531_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|274948
NZ_CP018786.1\|WP_079240179.1\|264597_266214_+\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|236471
NZ_CP018786.1\|WP_079240192.1\|291117_293085_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319847
NZ_CP018786.1\|WP_079240186.1\|273750_274065_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240185.1\|273061_273646_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240178.1\|263564_264470_+\|30S-ribosomal-protein-S6	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240184.1\|272449_273058_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240193.1\|293251_293575_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP018786.1\|WP_034691375.1\|290652_291072_+\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	2.17077e-16
NZ_CP018786.1\|WP_079240182.1\|267597_270531_+\|TonB-dependent-receptor	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP018786.1\|WP_079243827.1\|283035_287397_+\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
NZ_CP018786.1\|WP_079240179.1\|264597_266214_+\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	0
NZ_CP018786.1\|WP_079240192.1\|291117_293085_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319847	cd07548, P-type_ATPase-Cd_Zn_Co_like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis CadA which appears to transport cadmium, zinc and cobalt but not copper out of the cell. Bacillus subtilis CadA/YvgW appears to transport cadmium, zinc and cobalt but not copper, out of the cell. Functions in metal ion resistance and cellular metal ion homeostasis. CadA/YvgW is also important for sporulation in B. subtilis, the significant specific expression of the cadA/yvgW gene during the late stage of sporulation, is controlled by forespore-specific sigma factor, sigma G, and mother cell-specific sigma factor, sigma E. This subfamily also includes Helicobacter pylori CadA an essential resistance pump with ion specificity towards Cd(2+), Zn(2+) and Co(2+), and Zn-transporting ATPase, ZiaA(N) in Synechocystis PCC 6803. Transcription of ziaA is induced by Zn under the control of the Zn responsive repressor ZiaR. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP018786.1\|WP_079240191.1\|289738_290635_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.65945e-107
NZ_CP018786.1\|WP_079240190.1\|288840_289722_+\|hypothetical-protein	gnl\|CDD\|226304	COG3781, COG3781, Predicted membrane protein [Function unknown].	6.72543e-47
NZ_CP018786.1\|WP_079240177.1\|262679_263555_+\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	1.06246e-121
NZ_CP018786.1\|WP_079240183.1\|270549_272043_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	3.64839e-43
NZ_CP018786.1\|WP_079243828.1\|287479_288709_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	2.20068e-37
NZ_CP018786.1\|WP_079240181.1\|266762_267170_-\|3-dehydroquinate-dehydratase	gnl\|CDD\|376496	pfam01220, DHquinase_II, Dehydroquinase class II.	6.96217e-75

>NZ_CP018786.1|WP_079240186.1|273750_274065_-|hypothetical-protein
MELIQFYNYYIPALELALSEENINKATYNIKDPTQFLVEDKNILKEIDLFLDNASGENIFLDMVAYYFDAISHNFSSINNRDINDIRLLIWENIYDIKKKYNIN
>NZ_CP018786.1|WP_079240185.1|273061_273646_-|hypothetical-protein
MVTAFNFLAHKTETTNKIRSKIDKYYNDKSVADASVKEGFLNDLAKIFPEIYELTAKNFAIANEGNLKQFNESTGEDYVLIGKTIVSNSGNGENINGITSMKDGSVLISPHRTRTALGFAATWYHEGVHSLHLITGIFETWKIRYGAKEAIRITEFYAHSMTDAMSGLSMTSSLAFSRYYPSLYIQSLSSFLKP
>NZ_CP018786.1|WP_079240184.1|272449_273058_-|hypothetical-protein
MKNIILIILLAGTIKSDCYDFQIITKIIENQYLNVNIKNNSKKTLIFYNGDFESILKIVDENGVENIGEITSMFSGEDYLDYQFDYSKNLINKTMKKYSISFHDAVVYLHYRKKYILIMPNMAMDVNLPIVNRNYKMAYKLDSTKSYFLTISTVFSTEYIPKYVKDSLESKNVQIITPKINSNKININMDKFFRKHKHLYMK
>NZ_CP018786.1|WP_079240183.1|270549_272043_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKLKYISFALIGFLSLTSCESELDTAPTDQASSVEVFKTAESAETVVNGTWAKFNNDGTTYANIGYSTVLRASDAMGSDVAVLTNKYGFASTYAFTEMVNSTASRPLFIWTMLYSTINNMNNVITRIDGTEGSQEKKNQVKGQAKALRAFCYLNLASFYQFSYLKDKSALTAPIYTEPSTTTTVGKKRASLEEIYTLIKSDLTDADNLLKTYTRNNKDKINRAVVNGLLARTYLNTGEWSKALASAKIAREGFPLMAPEKYKDGFNDINNAEWIWGHGQTQEQSDASYAFHYLDVSSSGSYYYSFMADPYFKDLFDGNDIRSQLFSWDGQKGREGLLRYAKFKFKPTLIADIVYMRAAEMYLIEAEAEARTGNVSQAVAVLNQLKSARNANIYNGSLSQNEVVAAVLVERRKELFGEGFSLSDIIRTQGAVVRKPFVDADGKPIKVQITTPDGTVKTVDGRGHSVLDFPDKSAFTANSNYYLFSIPQRESENNPNL
>NZ_CP018786.1|WP_079240182.1|267597_270531_+|TonB-dependent-receptor
MISKNLFNSKTWIPPVAAFFLGIISVNAQNSKPKKDSLHEKEIDEVVVVAYGKAKRNSYTGSVATISSDKINNRPVTNITKALEGQVAGIQTTSASGQPGAVSTIRIRGIGSISASSDPLYVVDGIPFDGNLNSISPSDIESISVLKDATASALYGSRGANGIIIITTKSGKKGEARVNFNISQGFSGRAVKDYEQVNTDQYFQLYWEALRNGYQSGKVSSQQAAQMATDNLVSSLGINPYGTAYPKPVGTDGKLLPGASPLWNDDWRDILQRVASRNQVDLDISGGSEKSNYFFSLGYLDDKGMAIESGYKRYNTRLKINSEVKKWLNVGVNLSYTNSIQQAPTSSDSKASNIINAARFIPSFYPYYERNADGTYILDADGNPIYDFGKYRPTNALQNQNAAATLPLDKNENKEDNFSGKGFMEFTFLPELKFKTSFSVDLVNYNGHYYSNPLLGQGAEIGGSVTKTNTRTLSYTTSNILTYDKRFGKHHVNALAGHEFYKYDYQTISGTRSQFSLPYYYEPDAASLLGSFSGNSNKLSLLSFLGKVEYDYNNTYFLSASGRADSSSRFAKDNRWGRFWSVGGSWKISNEEFIKSLNVFNQLTLRASYGGQGNDKLLRPNGQPLYYAYQELYRFISLGGEPGTTLEKTSTNNVKWETNLNLNVGLEFAILNNRIKGNIEYFKRKSQDLLFNMPVAPSLGISDYPANIGTIQNTGFEFSLFTTPIKNDNFQWNVDVNLSTLNNKVTKLPGGSLVVGTKLLTVGGSVYDFFIPEWAGVDPSNGKPLWKTVTTDASGNSVEGTTSEYSKATKLLQGSALPKLTGGISTSITYKNFDFSGLLTFKIGGKILDTDYTSIMHNGSAGGRAWSAEMLNRWTPENPYTDVPGLSTTTNNWTSTSSRFLYSGTYARLKNVSLGYTLPEDYFEKIGLKKFRIYIQAENLLTFYKHKGMDPEQALDGTTYYRYPAMRTITFGLQATL
>NZ_CP018786.1|WP_079240181.1|266762_267170_-|3-dehydroquinate-dehydratase
MKVLIINGPNLNLLGTREPEIYGNVSMESYLENLKSEFQSHEIQYYQSNIEGELINRLQEDNFDAVVINPGAFTHYSYAIADCLKNIRKPKVEVHISNIYKREEFRQKSVTAANTDAVLSGFGMDGYRLALLSLK
>NZ_CP018786.1|WP_079240180.1|266261_266699_-|hypothetical-protein
MKIKDKIYCKIIGPYSGQLTKRKSYIIEEINVENIKVWNNEGKLRWYSKLYFSADNEPEIISINIDDPIENIESDAIEVTITFSNKVKYWMTFATPKYLDKILDEESYFSSKHFMIIKHLTEESIKSTVLKLDEQNELIENCKKY
>NZ_CP018786.1|WP_079240179.1|264597_266214_+|phosphoenolpyruvate-carboxykinase-(ATP)
MKNTKIIQDLEKLGIKGNYEVVYNPSYEELYQAEVSSENQGFEKAELTESGAVSVKTGIFTGRSPKDRYIVQDDVTRDTIFWDGKVNLPTTAEIFGSCKELVLNQLAESKKIYVVDTFCGTNADTRLKVRFIVEVAWQAHFVTNMFIRPSHYELENFGEPDFTVINGSKTINPNWEAQGLNSENFIMFNLTEKLQIIGGTWYGGEMKKGMFAMMNYYLPLKGMASMHCSANVGEKGDVALFFGLSGTGKTTLSADPKRYLIGDDEHGWDNNGVFNYEGGCYAKVIDLSEEKEPDIFAAIKRDALLENVVVNNGVADYTDGSITENTRVSYPIYHINKIVLPSKAGHAKKIVYLSADAFGVLPPVSILNEDQAQYHFLCGYTSKLAGTERGITEPQPSFSPAFGEAFLTLHPTMYSKTLIGKMQEHGAKAYLVNTGWNGTGKRISLKDTRAIIDAIIDGSIDNAPKTQVPIMNLEIPTELPNVSTGILDPRDTYESASEWEEKAKDLASRYIKNFEQYCDTEEGKKLVASGPQLQEQTI
>NZ_CP018786.1|WP_079240178.1|263564_264470_+|30S-ribosomal-protein-S6
MSAIFSPGKLMLTSEYFAIDGALVLAVPTKLGQEFFFEEKEDGKSLILWEAYHQNTLWLKAVIDYKTWQILETNIPSSAEFITKTLQNVQQLSNSKFKTDLTYHLKTNLQFPADYGLGSSSTLMNNLAEWAGIDPFYLNTISLGGSGYDIAVAKEKAAVLFQSKPEIKYEKVNFNPSFKNELIFIHLNQKQDSREGINFYKSKKKSPELVNEFSDLTKKILLCNELENFSELMMVHEHKIANFLEISTVKEKLFSDCPSFVKSLGAWGGDFVMSAKFGGYKNYFWEKGLPSVFEWENIIDL
>NZ_CP018786.1|WP_079240177.1|262679_263555_+|ACP-S-malonyltransferase
MKALVFPGQGSQFVGMGKELYDSRKDIKDLMESANEILGFDILSIMFNGTDADLKKTEVTQPSIFIHSVAALKAVNGLGAEMVAGHSLGEFSALVANGVLSFDDGLKLVSERAKAMQEACDANPSSMAAILGLDDAKVEEICAQISGIVVPANYNCPGQLVISGETPAVEEACAKLKEAGAKRALLLPVNGAFHSPLMQPAQERLAAAIEKTKFRKATIPVYQNITTTAVTNPDEIKQNLIAQLTGPVKWTQSVQNMIKDGASNFVEVGPGKTLQGLIKKIDGSVEATSAI
>NZ_CP018786.1|WP_167595377.1|280863_281331_-|hypothetical-protein
MKRKLLSLSSLMIGFFGFSQTEIYFKYDEAGNQRYRGIDAAGKKAEEIVSKESKVAAVARQVPVIDEKTFLKQIRLYPVPVNDYLTIDWTEEVDGLIESVSLYQHNTVHWKFQQQNIPNLNRQIKINMTGYDWGVYVVRFTLKDGRIFSKNITKR
>NZ_CP018786.1|WP_079240189.1|282564_282888_+|hypothetical-protein
MNLLRWILAFYFMALSLMPCEDTSHPLNSGDNKISLSIHGVHSTEKGDICSPLCACSCCQMTVSAFKMDPLLEIPEQIPAYFSKKILFHKNDFAYQIYDPIWQPPKI
>NZ_CP018786.1|WP_079243827.1|283035_287397_+|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MLDKIIKFSIKNKVIIGLMTLVLIIWGTWSATRLPIDAVPDITNNQVQIITVCPTLAGQEVEQLVTFPIEQSIANVPDIQETRSISRFGLSVITVVFKENVDVYFARQLINEQLKNAVEEIPKGVGTPELAPVSTGLGEVYQYILHPKKGSEKKYNAKELRTMQDWIVRRQLNGTPGVAEINSFGGELKQYEVAIDPNRLKAMGTSITEIFTALEKNNQNTGGAYIDKKPNAYFIRGIGLVTSLEDIKNIAVKNETGSVPIFIKDVADVRLGSAVRYGALTYDGKVDAVGGVVMMLKGANSNEVVNNIKAKIPTIQKSLPNDVIIEPFLDRTDLVDRAINTVQKNLVEGALIVIFVLVIFLGNLRAGLIVASAIPLSLLFALGMMNVFGVSANLMSLGAIDFGLIVDGAVIIVEATLHHLGVRKSARALTQSEMDEEVFLSASKIRSSAAFGEIIILIVYIPILTLAGVEGKMFTPMAKTVGFAILGALILSLTYIPMMSALFLSKKISHKETFSDKMMNSLQKIYQPLLQKSIKMKYAIVSATAVVFLISAFIFKNMGGEFIPQLQEGDYAFHCILPQGSSLSQSIETSMQASRIIKQFDEVKMVVGKTGSAEVPTDPMPPEATDMIVVLKPQSEWKTKKSYDELADEISEKLETIPGVFFEKNQPIQMRFNELMTGIRQDVAVKIFGENLDSLAVYADKVGKIIQTVDGATAPQIERVSGLPQINVQYDRTRIANYGLNIEDVNNAVSTAFAGKAAGQVFENERRFDLVVRLDSLHRTDISDVNNLMITSATGAQIPLSQVANISYKLGPAQISREQGKRRIVIGFNVKDRDVESVVKDIQAKLDKVKLPSGYYFTYGGQFENLQEASKRLMIAVPVSLLLIFMLLYFTFRSFKQAALIFTAIPMSAIGGVFALLIRDMPFSISAGIGFIALFGVAVLNGIVLIGTFNQLEKEGETDILKRVFEGTKTRLRPVLMTATVASLGFLPMAISTGAGAEVQKPLATVVIGGLVTATFLTLFVLPMLYIIFNTKILKRKNNNPGTFTVVLVLGFMMLGQTFKAQSRPVSVEQAVEQAVNNNLTLQSKDLSIKSAEALRATAKELPKLSFEAQLGQYNSPKFDQSFAISQSIPFPTLFKARKDVINENIKSKQIDKEITANELIKQVRTYYYQIEYLQYNKAQLTSLDKYYEEFIRIATVRFKAGDIKKIEISTAETQKGEIDLLLRQNEVFLNNAYKNLKTLMNTSEDFEVPFNKDYVPLKAENVLDSAVVANNPSVRAFYQEMEIAEKNKKVEKSLGLPDFSLGYTNQSLIGLHTINGQENFYNSGKRFQSATVGVAIPLTFGATKARIQALEYDRQVAETNAKMQKKQLAAQLENAFSQYQQDIQQYDYYTSQALPNAEKIVKAAQLGYKTGEISYVEYLFALQTATNIQLKYLESIQQVNQSVVIINSIINK
>NZ_CP018786.1|WP_079243828.1|287479_288709_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKLKYNIIPFILISLLLTSCGKKEAAEEKAPEKTEQKEAAHEEAPQTIASLTEDQMKSVGVALGVVEMKELTSTIKANGLLSVPNSNKATITSLYGGIIKTINIQVGSIVKKGQVIATIANPEYIQLQEDYLTTNSRITYAEQEYRRQRELFDNDAGAKKNLQSADAELKILRTKRASLLKQLQMMGISPGKVNNGNMRSGLVITAPISGTISSITAQIGSYVDISSPVATVIDNGSIHLDLQVFEKDLPKMRVGQIVHFKLTNNPETEYDARIYSIGSSFENESKTISMHCEVIGNKSGLIDGMNITGIVSLDKSTTPAVPTEAIVEADGKYFVFVQTDKEVEEEHEEKGKPHPKALNFEKIEVVKGASDMGYTAITPVGNIPDNAKIVVKGAFFVNAKLVNSGEHEH
>NZ_CP018786.1|WP_079240190.1|288840_289722_+|hypothetical-protein
MLLNKKISVWYFIREIKSQILFIGIFAVAIGLLDMLPWFRKISLPLNIPALLGTAVSLLLAFRTSQSYERWWEARTVWGAIVNDSRTFVRLIIQFMPAGEDKTVKDFAERQIIWTYALGEALRKLPFSEKVQQYLDQHKIKAVNIPNAILDEHSRQLKEIAASKGLTDFQQMQLNDIITRLCDSMGKCERLKNTVFPRSYSVLVHILIYVFAAILPFGLDDSQLAVEIAITFLVPVTFIAIEKTSIIMQDSFENSPVDTPMTSLAQTIEINIRQMIGEQNVPPKKENTSYYEM
>NZ_CP018786.1|WP_079240191.1|289738_290635_+|cation-transporter
MESTPIQTVSAGSRHKKNLLIVLCLSGTYLIAEVIGGIVTNSLALLADAAHMLTDVVGLLLAFIAIKIGERKADPSRTYGYYRTEILAAVINAVVLLGISIYVLFEAYKRFQNPPEVQSKSMLIVAGIGLIVNIVGMMILRKDSEGSLNMKGAYFEVLSDMLTSVGVMIAGVIMLTTGWYYADPLISAAIGLLIFPRTWRLLKEAINVLLEGTPKDVDIHELRKSLEQTPGVKNIHDLHVWSLTSSVNAMSAHVVKEAAYAQNQLLKTLTDTTVNNFKISHTTFQIEEEGYEENEVHL
>NZ_CP018786.1|WP_034691375.1|290652_291072_+|transcriptional-repressor
MKKDIEHKLIDKNTKPTSMRILVYDFLSSQEAALSLSEIENHFENADRITIYRTLKTFEEKGIVHSIQENTTTKYKLCEDDCDEKTHKDWHLHFYCKICKQTTCKEDISFPENIQTNFRIDEIRLFAKGICENCLESLQ
>NZ_CP018786.1|WP_079240192.1|291117_293085_+|cadmium-translocating-P-type-ATPase
MEKCCSTTPEKPDTKGHKHNHAEGDGHDHSHDSGDQTVFQMFLPAIISFVILLLGIAFDNYIKPAWFTGWVRLVWFLAAYIPVGFPVLKDAYKSIIKGDVFSEFFLMSIATIGAFAIGEYPEGVAVMLFYAVGEVFQSMAVTRAKGNIKALLDQRPDEVTIIENNQPKTIKAKEAKISDIIQLKPGEKLALDGELLSDSASFNTAALTGESKPDTKNKGEAVLAGMINMNSIALVKVNTAYEDSKLSKILELVQNATAQKAPTELFIRKFAKVYTPIVVFLAIGICLLPYFFVSDYQFRDWLYRALIFLVISCPCALVISIPLGYFGGIGAASRNGILFKGSNFLDSIAEIQNVVMDKTGTMTEGVFKVQEVSMAPEFNKEEILQMVNVLESKSTHPVATAIHNYVGDVNHNIPLENVEEIAGHGLKATINGKELLVGNFKLMDKFNINYDLNHANIVYTVIAVAYDKKFAGYITIADSIKEDAKETVDNLHKMNVKATMLSGDKSTVVKYVADQLGIDNAFGDLLPEDKVNKVKEIKARKQTVAFVGDGVNDAPVVALSDVGIAMGGLGSDATIETADVVIQDDKPSKIPMAINIGKQTKKIVWQNIVLAFAVKAVVLVLGAGGLATMWEAVFADVGVALLAILNAVRIQRMKF
>NZ_CP018786.1|WP_079240193.1|293251_293575_+|hypothetical-protein
MTDNYNRYKDNTHTLSFRRNLCKNIREINQTSIAILSEIKSLRLKKTVNIKKLASLRFQHYTTPKLNSKKVIDFLLEKRKGAKEIKIVLFLRTQENQRFSARLFIND
>NZ_CP018786.1|WP_079240194.1|293934_294297_+|hypothetical-protein
MRLFISIFVIFTIALRPVLPLVNYAVNYDYIVKNLCENRNVPQSTCKGKCYVEKELAKTEKQSNSSQTIKIAGLDAFISHDILSFSSLLNSELLTEIPDSSYFNSHSSEYFSRIFHPPLA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP018786_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018786_2

980347-980569

Orphan

Consensus_repeat	Method
GATCGGAAGAAGAAATGATGCTTCT	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP018786_2

>merge|NZ_CP018786|2|980347-980569|CRISPRCasFinder
GATGGGAAACAGAAACTCTGCTTCAACTTGGCAATTAGGAGTACTTAACTCTACAGAACAAACTCAGATCGGAAGAAGAAATGATGCTTCTTCAGTACAGATTGGATTAGGAAACTATGTTTTCCAATATCAGGATGGAAGAAGAAATGATGCTTCTGCTGTTCAGGTGGGTATTGGGAATGACGCTTATCAGGTTCAGCTAGGAAGAAGAAATGATGCCAGC

>NZ_CP018786|2|2|980347-980569|CRISPRCasFinder
GATGGGAAACAGAAACTCTGCTTCA	ACTTGGCAATTAGGAGTACTTAACTCTACAGAACAAACTCA
GATCGGAAGAAGAAATGATGCTTCT	TCAGTACAGATTGGATTAGGAAACTATGTTTTCCAATATCA
GGATGGAAGAAGAAATGATGCTTCT	GCTGTTCAGGTGGGTATTGGGAATGACGCTTATCAGGTTCA
GCTAGGAAGAAGAAATGATGCCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018786.1\|WP_079240675.1\|986612_987080_-\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|224678
NZ_CP018786.1\|WP_034697159.1\|983965_985477_+\|carboxypeptidase-like-regulatory-domain-containing-protein	unknown	unknown	gnl\|CDD\|274305
NZ_CP018786.1\|WP_079243854.1\|985748_986396_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP018786.1\|WP_079240676.1\|987250_988810_-\|ribonuclease-E/G	unknown	unknown	gnl\|CDD\|378414
NZ_CP018786.1\|WP_099049832.1\|981002_981401_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240674.1\|982589_983954_+\|curli-production-assembly-protein-CsgG	unknown	unknown	gnl\|CDD\|367655
NZ_CP018786.1\|WP_079240666.1\|973659_974364_+\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NZ_CP018786.1\|WP_079240663.1\|971446_971914_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP018786.1\|WP_079240668.1\|975657_976272_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_002984212.1\|989178_989469_-\|integration-host-factor-subunit-beta	unknown	unknown	gnl\|CDD\|259858
NZ_CP018786.1\|WP_034697153.1\|989787_990459_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP018786.1\|WP_079240673.1\|981411_982143_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|337812
NZ_CP018786.1\|WP_079240664.1\|971913_972348_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182510
NZ_CP018786.1\|WP_034697196.1\|982154_982565_+\|curli-assembly-protein-CsgF	unknown	unknown	gnl\|CDD\|371165
NZ_CP018786.1\|WP_079240667.1\|974504_975563_+\|nitronate-monooxygenase	unknown	unknown	gnl\|CDD\|240081
NZ_CP018786.1\|WP_079240670.1\|977667_978105_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079240671.1\|978954_979584_-\|CoA-pyrophosphatase	unknown	unknown	gnl\|CDD\|239518
NZ_CP018786.1\|WP_034697173.1\|978120_978927_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NZ_CP018786.1\|WP_079240665.1\|972680_973556_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NZ_CP018786.1\|WP_079240669.1\|976323_977661_-\|peptidoglycan-synthetase	unknown	unknown	gnl\|CDD\|223844

Protein	Function_ID	Function_description	E-value
NZ_CP018786.1\|WP_079240675.1\|986612_987080_-\|OsmC-family-protein	gnl\|CDD\|224678	COG1764, osmC, Organic hydroperoxide reductase [Secondary metabolites biosynthesis, transport and catabolism].	3.95191e-27
NZ_CP018786.1\|WP_034697159.1\|983965_985477_+\|carboxypeptidase-like-regulatory-domain-containing-protein	gnl\|CDD\|274305	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB. Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	1.09888e-12
NZ_CP018786.1\|WP_079243854.1\|985748_986396_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.63665e-36
NZ_CP018786.1\|WP_079240676.1\|987250_988810_-\|ribonuclease-E/G	gnl\|CDD\|378414	pfam10150, RNase_E_G, Ribonuclease E/G family. Ribonuclease E and Ribonuclease G are related enzymes that cleave a wide variety of RNAs.	6.57337e-125
NZ_CP018786.1\|WP_079240674.1\|982589_983954_+\|curli-production-assembly-protein-CsgG	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	8.63373e-77
NZ_CP018786.1\|WP_079240666.1\|973659_974364_+\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	3.15806e-45
NZ_CP018786.1\|WP_079240663.1\|971446_971914_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	5.38837e-12
NZ_CP018786.1\|WP_002984212.1\|989178_989469_-\|integration-host-factor-subunit-beta	gnl\|CDD\|259858	cd13836, IHF_B, Beta subunit of integration host factor (IHFB). This subfamily consists of the beta subunit of integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms.	4.67575e-32
NZ_CP018786.1\|WP_079240673.1\|981411_982143_+\|hypothetical-protein	gnl\|CDD\|337812	pfam10627, CsgE, Curli assembly protein CsgE. Curli are a class highly aggregated surface fibers that are part of a complex extracellular matrix. They promote biofilm formation in addition to other activities. CsgE is a non-structural protein involved in curli biogenesis. CsgE forms an outer membrane complex with the curli assembly proteins CsgG and CsgF.	4.07427e-10
NZ_CP018786.1\|WP_079240664.1\|971913_972348_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182510	PRK10514, PRK10514, putative acetyltransferase; Provisional.	1.46093e-44
NZ_CP018786.1\|WP_034697196.1\|982154_982565_+\|curli-assembly-protein-CsgF	gnl\|CDD\|371165	pfam10614, CsgF, Type VIII secretion system (T8SS), CsgF protein. The extracellular nucleation-precipitation (ENP) pathway or Type VIII secretion system (T8SS) in Gram-negative (diderm) bacteria is responsible for the secretion and assembly of prepilins for fimbiae biogenesis, the prototypical curli. Besides the T2SS that can be involved in the assembly of prototypical Type 4 pilus, the T4SS that can be involved in the biogenesis of the prototypical pilus T, the T3SS involved in the assembly of the injectisome and the T7SS involved in the formation of the prototypical Type 1 pilus, the T8SS differs in that fibre-growth occurs extracellularly. The curli, also called thin aggregative fimbriae (Tafi), are the only fimbriae dependent on the T8SS. Tafi were first identified in Salmonella spp and the controlling operon termed agf; however subsequent isolation of the homologous operon in E coli led to its being called csg. In the absence of extracellular polysaccharides Tafi appear curled, although when expressed with such polysaccharides their morphology appears as a tangled amorphous matrix. CsgF is one of three putative curli assembly factors appearing to act as a nucleator protein. Unlike eukaryotic amyloid formation, curli biogenesis is a productive pathway requiring a specific assembly machinery.	1.91215e-47
NZ_CP018786.1\|WP_079240667.1\|974504_975563_+\|nitronate-monooxygenase	gnl\|CDD\|240081	cd04730, NPD_like, 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	8.22924e-75
NZ_CP018786.1\|WP_034697153.1\|989787_990459_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.67532e-22
NZ_CP018786.1\|WP_079240671.1\|978954_979584_-\|CoA-pyrophosphatase	gnl\|CDD\|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	1.01385e-44
NZ_CP018786.1\|WP_034697173.1\|978120_978927_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	1.63098e-19
NZ_CP018786.1\|WP_079240665.1\|972680_973556_+\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	2.7595e-155
NZ_CP018786.1\|WP_079240669.1\|976323_977661_-\|peptidoglycan-synthetase	gnl\|CDD\|223844	COG0773, MurC, UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane].	7.93691e-78

>NZ_CP018786.1|WP_079240671.1|978954_979584_-|CoA-pyrophosphatase
MENFGKDLLRKIKSVALPGEHAHGVFSPPYRPVFTYDEVLSKNPKFAAVNIVLYLKDNEWYFPLIQRTINEHDRHSGQISLPGGKREEMDRDFAETAVRETSEEIGIDKHYVRIIREMSPIYIPPSNFYVYPYISYTKKNPAFVLQQTEAVETIEFPITSFLNLSDTPEIMALPSAGGHDVPVINFNGYIIWGATAMILSEFSQLLKKM
>NZ_CP018786.1|WP_034697173.1|978120_978927_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MAKKNIFTDAFGTPYFLKRFIIFILGIVSYRRFNGFNKLKITGTEHLVDLPDSNVLFVSNHQTYFADVAAMYHAFCAVNNGYLNTIKNPIYLLNPKIDFYYVAAEETMNKGILPKIFKIAGAVTVKRTWRAEGKNVNRMVDMSEVDNIMKALDNGWVATFPQGTTSAFAQGRRGTAKLVKNQRPIVIPIKINGFRRAFDKKGLRVKVTGVKPTMEFKAPLDIDYDNEKAPEILLKIMTAIEQTEDFNVLHSYDEELKAKKLEQKDSNN
>NZ_CP018786.1|WP_079240670.1|977667_978105_-|hypothetical-protein
MNKILGILFAIIVLVSCNSQKVYSDFDISYSKSGGVAPIYENLLIKGNNVHYSFEGQGKKYKQDFKISDEDLKKLDQVLSQNNFRRIQEDRKKLYDNISTSINIKKGPNEGSKTDASMIIPNYNTNWKNILEAFQQIINTNVKKQ
>NZ_CP018786.1|WP_079240669.1|976323_977661_-|peptidoglycan-synthetase
MKTHFIAIGGSAMHNLAIALKDKGYQVTGSDDAIFEPSKSRLEKKGILPQEMGWFPEKITQDIDAVILGMHAHQDNPELARAKELGLKIYSYPEFLYEQSKNKTRVVIAGSHGKTTITSMILHVLNFHQKDVDFMVGAQLEGFDCMVKLTQDNDFMVLEGDEYLSSPIDLRSKFLLYQPNIALMSGIAWDHINVFKTFDDYIEQFRKFVASITAGGVLVYNEEDPEVVKVVENAENYFRKIPYKTPEYEINNGKVYLKTEMGDVPLSVFGAHNLLNLEGARHICQQLGIMDEDFYEAIMSFKGASKRLEKVEREDKATLYKDFAHAPSKVKAAVKAFAEQFKNDKKYGFLELHTYSSLNPAFLEQYDHAMDGLEEAIVFYSEDALKIKRMEPISPEFIKEKFKNEKLKVFTNAEDLHAYWNTLDKTDGVYLMMSSGNFGGLDLTK
>NZ_CP018786.1|WP_079240668.1|975657_976272_+|hypothetical-protein
MKYSEGIQRSLPFGYLFLVIMGILKESVFYYQININILKYSTIMDILISPIATLTAHPIILIALIIIVVFSFAFPSFLSRQANKNKRWAFQMASLKGHENMSKEAIENHFTNMFVKFLAMMLLSFFVGIGWGEGLGLTRKIRENKLKYDYKLNYGDDSFEQVHLIGSNSMYYIYLAKGNKTIKIAPLGSIKSIELTNNKKLSDN
>NZ_CP018786.1|WP_079240667.1|974504_975563_+|nitronate-monooxygenase
MFWPDTISKKLGIQYPLIQAPMFGVSTVEMAVAATKANCLGSLALADLSADQSVELIRETKKLTDKPFAANIFVHHIPEVTDALKEKYGKTKLFIEQLAKENAIEVHLPDLEEIRVNGYHDQVDAIIQEDCKILSFTFGNLDDQSIQKLKENGVTLIGTCTSVREALLLENSGIDIICVQGIEAGGHRGSFEAENIPQIGGLSLLSQIYEQVKVPLIYAGGIYGAKTLQAVKELGAQGFQVGNLLLASQESALHPFEKERLKKVREEEIVLTKSFSGRYARGVKNHFIETVENSEYILPYPYQNKLTNALRKAAKSLQNPEFVGIWVGQSIHQYSELSTEEILKKLIKECER
>NZ_CP018786.1|WP_079240666.1|973659_974364_+|DNA-alkylation-repair-protein
MTAKEFIETLSLFKNEKELNKAEKFFKGNDGVTKSFGVKFGDVFTTAKAFSMMPLDEINKLLDSDFYEVRMGAVSIMDFQARSKKSSEDLKKALFDLYLNRHDRLNNWDFVDRAACHVIGEYLIDKSRDILHKLAYSDSPWERRTAIVSTHAFIRKNDVADTFAIAEILVYDPNELVNKAVGSWIREAGKKDKKKLQHFLNTYVKTMPAVTFSYATEKLDPESKLHYKELRKAK
>NZ_CP018786.1|WP_079240665.1|972680_973556_+|aldo/keto-reductase
MQKKTYTGQPVVTLNNGVDIPALGFGVWQMEDLKECENAVIKAIQTGYRMIDTAAIYQNETAVGTAVKNSGVKRDELFITSKVWVQDHGYEKAKSAFQRTLDRLQMDYLDMYLIHWPYGDFLGTWKALEELYHEGKIKAIGVCNFTVEKLEELKANSTVLPVINQIELHPVFQQKELQVYDRENNIVTQPWSPLGNGNANLLSNPDLKAIAEKYGKTVAQIILRWHLQEGFVVIPKSVTPSRIEENFNVFDFELTEDEMNVVRSLDTGKRLFFDPKDPEWEQKMLNSVADI
>NZ_CP018786.1|WP_079240664.1|971913_972348_-|GNAT-family-N-acetyltransferase
MSQNIRLATAEDYPRIMEIWESAVKATHDFLAEEDFNYFKEAIPRDYLPNLEVYLITENNESKGFASVAEGNLEMLFIHNDTRGKGYGKTLYQFMKEKTGLTKVDVNEQNPQAIGFYEKMGFKKTGRSEKDGSGKDYPLIHMSL
>NZ_CP018786.1|WP_079240663.1|971446_971914_-|GNAT-family-N-acetyltransferase
MENFTFNKLNSDSEIPYHLLLLADETREAINQYIFNSEIYLLHDGIENIAVMALYKKTHTELEIKNIAVIESYRNKGIGTILIDKAKEIAKENHYKTLIVGTSDTGFQQIIFYEKNGFIKSGILKDFFIENYPAPIYENGLQMRDMVLLSHHLAE
>NZ_CP018786.1|WP_099049832.1|981002_981401_+|hypothetical-protein
MFNLKWSVLALFIMLPLHAQEIDWDKVNSNTIFNLIARQQTDQSSYGSDIIQIGDYNNAELSLNARTNIIVRQLGDFNTLYFINSFTDKETKAAITAQGNNNIIDVTGSNSISDGIQINVKGDNRTVFMRNY
>NZ_CP018786.1|WP_079240673.1|981411_982143_+|hypothetical-protein
MKLLYSLSLGTFFTFLSVWVYGQEDKKVNARIESSVLENQVRLKAVVINNTAVYKELNYLLISIKKGNSGNLSNNQQNGKFSVNPNEVKILSEISVNLESKDALKAFLYIRDEETQKLIAKDSLELNSDLFKKKTAKIEEDAAYELRGLTIDETKTKVGKDFYDMFYMQYSQLPDKSSSVITITELPLRGTSGQINIQMEDKIIYSFMTNPAEDYLKEQLNYSLKYIKEFNAKKNLIKNEFIY
>NZ_CP018786.1|WP_034697196.1|982154_982565_+|curli-assembly-protein-CsgF
MKTFIIILTCIAGIFYGKAQQLVYKPVNPAFGGDTFNYQWLLSSANAQNPFDEKNDFSDLLDRVNSLDSFTESLNRQILSELSRKLFEEQFGDGNIKPGNYLFGSLYLQITNTNQGLLINILDTSNGDQSEIVIPK
>NZ_CP018786.1|WP_079240674.1|982589_983954_+|curli-production-assembly-protein-CsgG
MTTYTYTRIFFCTFLLCILQACSSIFGLPSDPEKPTMGEVTSSTAELKNLPLPKEKIVIGVYKFRDQTGQYKPSENGNNWSTAVPQGTTTILIKALEDSRWFVPIERENIANLLNERQIIRSTRQEYIKDADKNNQSLPPLLYAGILLEGGVISYDSNILTGGLGARYFGIGASTQYRQDRITIYLRAVSTLNGEILKTVYTSKTILSTSVNGSFFRYIDTERLLEAEVGLTQNEPVQLAVTEAIEKAVKALIVEGIRDKIWGKAIDENGGYQSLINEYNREQEQNNDRVVGGRYPQDYRQKVSIFANVEGQKIKDDYVGPKMNVGGKIGLKYFLTPYLNMELNASYFTLENSNIVKRNYYGPEVNLEYILFPKYRFSPFVYGGAGALYSKYKPQYKAQFGGGLEYMISKNFSLRASAQYDLGFKDDWEGLVNGKRKDQALRFGIGINFYFGNK
>NZ_CP018786.1|WP_034697159.1|983965_985477_+|carboxypeptidase-like-regulatory-domain-containing-protein
MKTIIKIFSIFIFAFCLFSCNEDLVEQAQTGMLKGKVVKRGSNVPLSNVKIFTNPTTQTVFSGTDGSFEIAAMPIGNYSVKAELSGYITSFQSVNIQNQNQVVTVVFEMDDDTSLNSPPATPQLLSPIDNAVNQPLSVELTWSATDPDTADVLRYSLTIKNNLDTNVIQVNDLTANHYTLSNLKFGVSYFWQVSVSDGIHQPVLSSISKFTTNTVPANRYHYVQKQNGNFVIISSDDQGNNFQFTSSSYNSWRPRKNNNAGLIAFLRTEGGSTHLYTANPDGSNPFKVTTVAVAGFNNYEMDFAWSTNGKELIYSNFNKLYRINKDGSGLSLVYTTPDGSLISECDWSYDGSKIALKTNDYNGYNTKIYVIDINGAVLKTVLSGTAGASGGLNFSVDGQLLLFTRDMSGYLDGSGNYRQLDSHIFIYNLVTDAVSDISAESEKVLGTNDLDPRFSPNNAQIIFMNTSNDNISQRNVMVIDLSSTLTDMTRTTLFSNGEMPDYE
>NZ_CP018786.1|WP_079243854.1|985748_986396_-|response-regulator-transcription-factor
MKPKLTIFDEPMLYTEGLSRLLTQSKIFSTIDICNSLENLSKYLKEEPSEMLVMSSNMLMLSEICKLVESIISEHKNTKIIIIGSSYDVIDIRKLFNKGIKAYLDKNCTYDEFLKSINVLLLNEIYICDHAKERMINFISSEQGKPNPHIKEPLTRREMEILKLICDGCSSKDISEKLFISINTVETHRKRILLKLNAKNSVGIVKYAIENHIID
>NZ_CP018786.1|WP_079240675.1|986612_987080_-|OsmC-family-protein
MKNHHYKITIQWTGNQGTGTSSYRDYERSHTISAENKTVIEGSSDPAFRGDKTKHNPEDMLLSSLSSCHMLWYLHFCSEAGIIVTDYTDEATGIMTETASGSGHFTEVTLHPTVTVAEESMIEKAEQLHHKANEFCFIANSVNFPVKHIPTTLVK
>NZ_CP018786.1|WP_079240676.1|987250_988810_-|ribonuclease-E/G
MKKELIVSHEDDLTKIALLEDGRLCELHEQEDKSDFIVGDLFIGKVKKLAPNLNAAFVNIGYDKDAFLHYQDLGPQYLTYRKFLKDTISKKQSTSSLKNFEIQPEIDKNGTVDKVIAKDDVVLLQITKEPISTKGPRISTQISLTGRFLVLIPFDNKVSISKKIRSFEEKERLRTLIDSIKPEGFGVIIRTVAEGKKVADLHNDMNQLVQKWESTFKNIQRNKVPSKVLSEEDKASAILRDNFNQDFVNIICDDEQMVNEMKNYIEVIAPEKKNIVQFYDSHIPLLEYYNVEKQLKQSFGKHVNIPSSKGAYLVIEHTEALHVVDVNSGNNITTGTAVNKEHALKVNKMAATEIARQLRLRDMGGIIVIDFIDMPNSDHRRDLYEHLKEEMKRDKARHKILPPSKFGLIQITRQRNRPEKQIDTKEENPNKDGEIVAPIVIVERMGETLRNILQKEKGKIYLHVHPFVEAYLTKGIKSIQMKWFIKYKKWVTIVPRDSFKYLEYKIYNAKKEELIEFSN
>NZ_CP018786.1|WP_002984212.1|989178_989469_-|integration-host-factor-subunit-beta
MTKAELVNTISNKLGTEKNETQKVVEAFMQEIRTSMYNGDNVYLRGFGSFIIKTRAAKTGRNISKNTAIEIPAHNIPAFKPSKSFVEKVKTKVAVK
>NZ_CP018786.1|WP_034697153.1|989787_990459_-|response-regulator-transcription-factor
MSKILSNTVRFSIADSDFYFKKIMIKTLMENPFYMLLNDCNNGHELVNRIYRRQEDVFIIELFMPVLSGIEAIKYIRKNNTETPIITYSGTYQEDMAEILSKIPNIYYCQKKSTIIKDIIKGSIASEDFDYQAYSKEWEQQPLAVQEYMDRQKKGQEELSPAEIQLMRFCYEGFSNKEIAEKLNLSTRTIDTYINRLTEKLGLKTKLHLIRFCVENGYYNSSL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP018786_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018786_3

1803396-1803616

Unclear

Consensus_repeat	Method
TTTCTGAATCCGCTGTTACTGTTGGA	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP018786_3

>merge|NZ_CP018786|3|1803396-1803616|CRISPRCasFinder
TTTCTGAAACCGCTGTTATTTTGGTTTCCCTGGTTGTTCTGATTACTGCTGTTTTGATTTCTGAATCCGCTGTTACTGTTGGAATTTCTGAAACCACTGTTGTTTTGATTTCCCTGATTGTTTTGATAACCACTATTCTGGTTTCTGAATCCGCTGTTGCTGTTGGAGTTTCTATTATTATTGAATCCTCCGTTATTATTGTATGAGCCGTTACTGTTCGT

>NZ_CP018786|3|3|1803396-1803616|CRISPRCasFinder
TTTCTGAAACCGCTGTTATTTTGGTT	TCCCTGGTTGTTCTGATTACTGCTGTTTTGA
TTTCTGAATCCGCTGTTACTGTTGGA	ATTTCTGAAACCACTGTTGTTTTGATTTCCCTGATTGTTTTGATAACCACTATTCTGG
TTTCTGAATCCGCTGTTGCTGTTGGA	GTTTCTATTATTATTGAATCCTCCGTTA
TTATTGTATGAGCCGTTACTGTTCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018786.1\|WP_079241201.1\|1816022_1817276_+\|TCR/Tet-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340946
NZ_CP018786.1\|WP_145953226.1\|1814538_1815807_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079241187.1\|1793733_1795335_-\|S8-family-peptidase	unknown	unknown	gnl\|CDD\|173818
NZ_CP018786.1\|WP_079241192.1\|1801371_1802397_-\|endolytic-transglycosylase-MltG	unknown	unknown	gnl\|CDD\|376862
NZ_CP018786.1\|WP_079241186.1\|1790987_1793522_+\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|173589
NZ_CP018786.1\|WP_079241199.1\|1813883_1814456_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_034696290.1\|1804783_1806301_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129987
NZ_CP018786.1\|WP_079241188.1\|1795423_1796548_+\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl\|CDD\|99740
NZ_CP018786.1\|WP_079241195.1\|1806351_1807365_+\|glycosyl-hydrolase	unknown	unknown	unknown
NZ_CP018786.1\|WP_079241197.1\|1808949_1810317_-\|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|369642
NZ_CP018786.1\|WP_079241190.1\|1796998_1798021_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|187558
NZ_CP018786.1\|WP_079241191.1\|1798658_1801238_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|379720
NZ_CP018786.1\|WP_079241196.1\|1807543_1808902_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236430
NZ_CP018786.1\|WP_079241202.1\|1817384_1818188_+\|arylamine-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225073
NZ_CP018786.1\|WP_079241184.1\|1789844_1790510_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_145953225.1\|1796551_1796989_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079241193.1\|1802430_1803198_-\|diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|234768
NZ_CP018786.1\|WP_079241198.1\|1810533_1813443_+\|protein-translocase-subunit-SecD	unknown	unknown	gnl\|CDD\|237276
NZ_CP018786.1\|WP_079241194.1\|1803956_1804619_-\|nicotinamide-mononucleotide-transporter	unknown	unknown	gnl\|CDD\|377432
NZ_CP018786.1\|WP_034696297.1\|1798160_1798613_+\|adenylyltransferase/cytidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|173922

Protein	Function_ID	Function_description	E-value
NZ_CP018786.1\|WP_079241201.1\|1816022_1817276_+\|TCR/Tet-family-MFS-transporter	gnl\|CDD\|340946	cd17388, MFS_TetA, Tetracycline resistance protein TetA and related proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of tetracycline resistance proteins similar to Escherichia coli TetA(A), TetA(B), and TetA(E), which are metal-tetracycline/H(+) antiporters that confer resistance to tetracycline by an active tetracycline efflux, which is an energy-dependent process that decreases the accumulation of the antibiotic in cells. TetA-like tetracycline resistance proteins belongs to the Eukaryotic Solute carrier 46 (SLC46)/Bacterial Tetracycline resistance (TetA) -like (SLC46/TetA-like) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
NZ_CP018786.1\|WP_079241187.1\|1793733_1795335_-\|S8-family-peptidase	gnl\|CDD\|173818	cd07493, Peptidases_S8_9, Peptidase S8 family domain, uncharacterized subfamily 9. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	8.56181e-100
NZ_CP018786.1\|WP_079241192.1\|1801371_1802397_-\|endolytic-transglycosylase-MltG	gnl\|CDD\|376862	pfam02618, YceG, YceG-like family. This family of proteins is found in bacteria. Proteins in this family are typically between 332 and 389 amino acids in length. This family was previously incorrectly annotated and names as aminodeoxychorismate lyase. The structure of YceG was solved by X-ray crystallography.	9.42944e-79
NZ_CP018786.1\|WP_079241186.1\|1790987_1793522_+\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|173589	PTZ00398, PTZ00398, phosphoenolpyruvate carboxylase; Provisional.	0
NZ_CP018786.1\|WP_079241202.1\|1817384_1818188_+\|arylamine-N-acetyltransferase	gnl\|CDD\|225073	COG2162, NhoA, Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism].	1.51363e-74
NZ_CP018786.1\|WP_034696290.1\|1804783_1806301_+\|amino-acid-permease	gnl\|CDD\|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.18755e-112
NZ_CP018786.1\|WP_079241188.1\|1795423_1796548_+\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl\|CDD\|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	2.12368e-145
NZ_CP018786.1\|WP_079241197.1\|1808949_1810317_-\|PQQ-dependent-sugar-dehydrogenase	gnl\|CDD\|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	6.47613e-41
NZ_CP018786.1\|WP_079241190.1\|1796998_1798021_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|187558	cd05247, UDP_G4E_1_SDR_e, UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.62051e-165
NZ_CP018786.1\|WP_079241191.1\|1798658_1801238_-\|TonB-dependent-receptor	gnl\|CDD\|379720	pfam14905, OMP_b-brl_3, Outer membrane protein beta-barrel family. This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.	2.18149e-89
NZ_CP018786.1\|WP_079241196.1\|1807543_1808902_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236430	PRK09249, PRK09249, coproporphyrinogen dehydrogenase.	0
NZ_CP018786.1\|WP_079241193.1\|1802430_1803198_-\|diaminopimelate-epimerase	gnl\|CDD\|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	1.249e-80
NZ_CP018786.1\|WP_079241198.1\|1810533_1813443_+\|protein-translocase-subunit-SecD	gnl\|CDD\|237276	PRK13024, PRK13024, bifunctional preprotein translocase subunit SecD/SecF; Reviewed.	0
NZ_CP018786.1\|WP_079241194.1\|1803956_1804619_-\|nicotinamide-mononucleotide-transporter	gnl\|CDD\|377432	pfam04973, NMN_transporter, Nicotinamide mononucleotide transporter. Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.	1.12697e-48
NZ_CP018786.1\|WP_034696297.1\|1798160_1798613_+\|adenylyltransferase/cytidyltransferase-family-protein	gnl\|CDD\|173922	cd02171, G3P_Cytidylyltransferase, glycerol-3-phosphate cytidylyltransferase. Glycerol-3-phosphate cytidylyltransferase,(CDP-glycerol pyrophosphorylase). Glycerol-3-phosphate cytidyltransferase acts in pathways of teichoic acid biosynthesis. Teichoic acids are substituted polymers, linked by phosphodiester bonds, of glycerol, ribitol, etc. An example is poly(glycerol phosphate), the major teichoic acid of the Bacillus subtilis cell wall. Most, but not all, species encoding proteins in this family are Gram-positive bacteria. A closely related protein assigned a different function experimentally is a human ethanolamine-phosphate cytidylyltransferase.	1.37688e-15

>NZ_CP018786.1|WP_079241193.1|1802430_1803198_-|diaminopimelate-epimerase
MEFYKYQGTGNDFVMVDNRDLQFTKDKDSIEKLCDRRFGIGADGLILLENDPEYDFKMVYYNSDGGESTMCGNGGRCLVAFAFFLDIFEDKCKFIATDGEHEAEIHNGIIKLKMINVDTVSHDGNDFVLNTGSPHYVKYVDNLKDYHVYDEGYGIRNSENYKEKGINVNFVEKISDNEIFVRTYERGVEDETYSCGTGVTASALTFLQKHNLTSVKVKTLGGNLKVYAEKSGDAFQNIWLEGPAKQVFRGKTDLL
>NZ_CP018786.1|WP_079241192.1|1801371_1802397_-|endolytic-transglycosylase-MltG
MKKAILIVILLVFVVAGFFGLRFYNKYLGNNVEKDGYVLIPHRAGFKQILDSIAPYIKDRESFEAVAKEKGLETNFKAGRYHIQSGTGNKNLVNMIKAGNQTANSYRIGDFGDMYQMIGKVTKKTEIDSLHFVNDLDAVAQEKGYKNVEDLKKYFFIDTYNFFWTVSPREFFAKFENQYHDFWTSDRKNKEQQSGLTRDQIYALASIVYKESGGKKDEMKTIAGLYLNRYRKGMKLQSDPTVIYAINKQTNFKEPIKRVLYKHLSTPSPYNTYANAGIPPGPICVVDKNSIDAVLNAENNNYIFMCADPARFGYHKFTASAEEHAVNAKAYQDWLNSKNIK
>NZ_CP018786.1|WP_079241191.1|1798658_1801238_-|TonB-dependent-receptor
MKNKTEIVNIFTRKTLGLTLVLSAAALAFAQEKAGVSGIIVNKKNQPVPYASVTFSNKANKTLSDAVLTDEKGQYTLQLMPGDYDITVEAIDYKKSVVSKNIAKAGNIGALSIEAEPTSTADGKTKEIQGVVITASASKAYKVELDKKTYDPSQDIVSKGGNLQDVLTNVPSVSVDTDGTVSMRGNSNVKFLINGKPSSLLGIDDGANALQSIPADQIERIEVITNPSSKFEASGTAGILNIILKKDKKMGFNGSVTGTLGYLPRTNLNANLNWRKGNWTWFLNGGGGYQKNESTMKNTTTRKDDIGSLSSTAFPFTQYSQQNGKTTRESDTYNVTAGFTHDFSDKTSINFSGMVRSFDTDQTGINAYNEKVYKDASTINDVVRERNSYGNNKNLATQFDLGLDQKIGDNGQLLSASASYQTNKTDGINQIVQRSFVNTILQPTSVVNNVSTDSKTDTFIGKIDYELPIGEKSKLEAGARYDYNRNTYNYFVDQSDNGQTPYTRFDFTSNTVYSENILGVYAQFKSKIGEKFAYQLGLRSETSKIDVNFQNFDVNGNPANTPEVNKNYTKFFPSVFLSYDLAKNNQILLNYSRRINRPRAFSLIPFMSFDDDRNYFRGNPNLNPTYENSFEVGYNLSNKKITFNPTLYFKKSEDEQNRYQYIDDTGAVNTIPFNVGTETNYGLDLNGTYDPYSWWKIMLSADLYGYKNTGSFNLFPDNPRTLNDFSGSGFSYRIRFNNTFKPTKNLSLQIQSFYRAAEKTAMNNRKAMYGIDLGVSQTIWKGNGIIGFNIRDIFNTRKMKNFSDNAQFTREMEMQWQPRQFALSFTYKFKQGEKIDAKPKIKKDINSNTKGDEEQGGPM
>NZ_CP018786.1|WP_034696297.1|1798160_1798613_+|adenylyltransferase/cytidyltransferase-family-protein
MKTQRIGITFSSFDLLHAGHIKMLEEAKTVCDYLIVGLQIDPSHDRPNKNKPSQTIVERYIQLKAVNAVDEIIPYYTEEDLLDILKSFVIDVRIIGDDYMDRDFTGKKYCEEKGIELFFNKRDHRFSTSDLRRRIYEAEKEKYAKAEPVK
>NZ_CP018786.1|WP_079241190.1|1796998_1798021_+|UDP-glucose-4-epimerase-GalE
MAILVTGGLGYIGSHTVVELLNNGFEVVIVDDLSNTEKFILKNIEEITGKKPVFYPFDLRRKELLTQVFDAHQIDGCINFAASKAVGESQIIPVDYYENNLFSLINILQEFKARKISNFIFSSSCTVYGQADVMPIDENTPLKTPESVYGKTKQMGEQILIDFAKAYQSKISLLRYFNPIGAHPSGKLGELPIGIPNNLVPYVMQTASGVREKLNIWGDDYPTEDGTAVRDYIYVVDLAKAHVAALKKLIEDSSSDAVIDTYNLGTGKGSSVLEVVKAFEKANHVEVPYQICARREGDITIAYANPDKAEKGLNWKSETSLEEALRTVWEWQKYLNTRNS
>NZ_CP018786.1|WP_145953225.1|1796551_1796989_+|hypothetical-protein
MKNRIFKYRVVGIVVFLFELFLLFLFSVGTYDSSMELGIKSVFSIETLIFIFSVSIFVSTFLSLILLLLKSKKTILYLNINYTLIILFFVLGYFKLWIEKSLEEDDNLKIFLTFSIISIVLFISNIFRNKKVQFLEMEDIGKSND
>NZ_CP018786.1|WP_079241188.1|1795423_1796548_+|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MKKIQMVDLQSQYYKIKNDVDNAVLNVMDSAAFINGPEVKSFQNELESYLEVKHVIPCANGTDALQIALMALDLKEGDEIITADFTFAATVEVIHLLKLKSVLVDVDYDTFTISTEQIKKAITPRTKAIIPVHIFGQCANMEEILKIAEEHNLYVIEDNAQAIGSEYTFSDGSVKQAGTMSTVGTTSFFPSKNLGCYGDGGAIFTNNDELAHRLRGIVNHGMYERYYHDEVGVNSRLDSIQAAVLRKKLPHLDSYNEARRKAADFYDEAFEGNPNILTPKRAENSTHVFHQYTLRILNGKRNELQKFLTEKEIPAMIYYPVALRKQKAYFQESNAADFVNTDKLLDQVISLPMHTELDEEQLKYITDAVLEFMG
>NZ_CP018786.1|WP_079241187.1|1793733_1795335_-|S8-family-peptidase
MKKLLLFCFLTGYLTVSAQTELVFVYFTDKPNKAAFYANPLSELSQKSLNRRTALGIPLNDQDAPIEQSYLQNLQNLGFVVTDYSKWLNGAAVNATPAQKTLLQAQTFVSSVESFARNSSTTVKTAPGKWKDDASINKTLTNFNYGSGAGQIDQVNIRPLHLAGYTGTGVSIAVIDAGFPTVNTGNAFSRLWTNNHIKASYDFVTKTGDIYNAALSTHGSVVLGVIGGYLQDVFVGAAPDADFYLYRSENAAVEIPEEELYWIEAAEEADRKGVEIITSSLGYNIFDESRYNYTYADMDGNTSFIARGAGIAAEKGIFVLAAAGNSGQQPWHYLMTPSDNAKVFSIGSVDSAGNASGFSSFGPNALGVVKPDGSTQGTGTTTVYDNATLVVNGTSIATPIAAGGVACLIQAFPTMNREQMRTKLRQTASLYPLHSDQTGFGILNFGSLYNLVLNTSETVKKEKFSIFPNPARNILNVASEQEIQSLEIYDNLGRLIRKSNHQKSIKVEDFAKGTYYLKIQTKDKVFYEKFLKE
>NZ_CP018786.1|WP_079241186.1|1790987_1793522_+|phosphoenolpyruvate-carboxylase
MIHDQRAEKFRQIVENKFQIYNSLFMSLPYDKMTNIGMLLPFLYEESRTGYEAGKTPEDIVEEFFKNHTDLQNEEQKLELLFKIIQYIERQVVLFDSIEDAAFPNLHSESDNGTVTNLFERSFQDHKIENVREKLKDFSVKVVFTAHPTQFYPSSVQRIIQDLRGAITSDSVTQIDMLLQQLGKTPFVNKEKPTPIDEALSIISYLRYVYYDTIGELFTKIKKTFGNGHFHLHEDIIQLGFWPGGDRDGNPFVTAEVTKRVAEELRSAILKSYYSHLKFIRRRLSFRGVSEVLTQLSEELYAAIFDGKTIKAEDILKKANEAEKILINEHNSLFLDLLVNFRDRVMIFGTHFATLDIRQDSRIHQKVIDEVYTKVYGNEDADHEQKFNKLIQISETVNAEDFEDIVKDTLLTVSQITDIQNLNGLRGMNRYIISNSDAVKDVMNVYAFFKICGYQNEEINMDIVPLFETMEGLANAEHVMNELYHNPVYKKHLEKRGNQQTIMLGFSDGTKDGGYLKANWEIYKAKEVLTKLSEQNNIKVVFFDGRGGPPARGGGKTHDFYASQGKTIANNKIELTIQGQTITSIFGNKEQAKYNFEQLLTAGVENDVFKNEKKELTEKERALIIELADISYKKYSDLKAHPMFVPYLQEMSTLEYYGKTNIGSRPSKRGSGSELKFEDLRAIPFVGSWSQLKQNVPGFFGFGYAMQKMKEQGRFEEVRELYKGSDFFKTLVLNSMMSMNKSYFPLTFYIKNNPKFGAFWNVLFNEYELSRDIMLELTGFKMLQEEDPLSRKSVKIREKIVLPLLSIQQYALMKIQKGEGNKEAYEKLVTRSLFGNINASRNSA
>NZ_CP018786.1|WP_079241184.1|1789844_1790510_-|hypothetical-protein
MKFGIIFYAILGSLTLFIGIYLLQYFIPLSIIFFIASFINGVFIHKEYSLHKSDKIEYDENSIPDEIIVKYSRSGRIIAIATYSMFMILGLFFLLGFKFKFNGTAIFVLFVLLGFTGYFIFKIISEVKKISQILISINGKGIQINDNTRYLWHEIQLEKIIVKRLVSRESKHDYKPEVNYLYFFHHNEKIEINIDDFDITDYQLAQVLKIFRARFNNSGLI
>NZ_CP018786.1|WP_079241194.1|1803956_1804619_-|nicotinamide-mononucleotide-transporter
MNLYDLFVKPYESYDSLQITLEASGAIFGILSVFFSIKKNIWVYPTGIISTLIYVYLLFNAGLLGDCMINVYYTVMSIYGWVLWARNSEDHVHVEVTWATRKEWIHASILFVLSLAFVTFIYYCKPYIDHLEGGYLGLYHLDWANWMDIFTTSIFLVGMWLMAKQRIESWIFWILGDLICIPMMIFKGLGITSVQYLVFTIMAILGYVNWKKSFKEKKVQ
>NZ_CP018786.1|WP_034696290.1|1804783_1806301_+|amino-acid-permease
MSKIWVKKPLSAYEADMKKSELKKVLGKWSLTAIGVGAIIGGGIFVLTGTGAYYHAGPALAISFIIAGIACVFAALCYAEFASIIPVEGSAYAYAYGTVGEIFAWAMGWCLILEYAMASMAVSVSWSGYFNKFLKIFNIHLPAYLTSDPASYTGDGFSMNLPAFILVLLITALLVKGTKEAAGANNLIVLMKTSAVIFVIIAGVYIIFSNTDLYNAVDGVKNWKPFIPDQVQIKNSEGDMVSAYGIKGIISGAAAIFFAYIGFDAVSTQAGEAINPKKDVPFAIIASLLVCTALYICVSLVLTGMMHYTDFNPEGKYPDAIKAPVAYAFEIAGKHWASNIVTIAATVGLISVVMVMMMGQSRIFIGMAKDGLIPKFFGDLHPKTKTPYKGIILLGLVVALIAAFTPISTLADMTSFGTLFAFTLVCIAVWVMRKKEPNLIRPFKVPAYKIVVALGVFINIYLIFNLSAHALELSAVWLFLGGLVYFLYGKSNSKLNNPEKYQNQD
>NZ_CP018786.1|WP_079241195.1|1806351_1807365_+|glycosyl-hydrolase
MKNILSILFLSIGITAFSQQVESLETILNDKISIRALELYDNKVWYSGTDSKFGFVDLKDYKSQKQIKLSEEKLQFRTLAQNKTIFYAINIESPGRFFAIDKKTLKSQIVFQDTAKTAFYDALHFVNDKLAYTFSDSDKDQMLKLAVYKEGKWSMFKNNVKLNEGEAAFAASNTNISSSKKYLWIATGGKASRILRMNLKDEKIEVFNTPIIQGESSQGMYSIDFFDNNFGIAAGGDYTKQDANINNIATTNDAGKTWQIQASGQNAGYTTCVKIKPGSKGKEIIAVGDKHISYSSDFGKTWTKISDEKGFFVCQWIDVNRVVLAGNNRIAVMKLKF
>NZ_CP018786.1|WP_079241196.1|1807543_1808902_+|oxygen-independent-coproporphyrinogen-III-oxidase
MNSLIDKYNIPGPRYTSYPTVPYWDESTFSPEKWKETVIRSFHESNAEEGISIYIHLPFCEALCTFCACHKRITKQHSVEVPYLESVLKEWKLYLDLFNERPKLKELHLGGGTPTFFSPENLRTLLEGIFSSVDIAEHPEFSFEGHPNNTTKEHLQTLYDLGFRRVSFGVQDYDPKVQKAINRIQPFENVKNVTEWAKEIGYRGISHDLVFGLPHQNWDAMEHTIRKTMELKPDRLAFYSYAHVPWVKGVGQRGFDENDLPSGEEKRRLYEDGKKLLQDLGYIEVGMDHFSLEHDDLYQSLIHKKLHRNFMGYTSSNTQLMVGLGMSAISDSWYAFAQNVKTVEEYQKMVEEGEIPVVKGHVLSDEDLTVRRHILNLMCQLETTFDVNNSFPELDNALEMLKEMENDGLVEINGTEVKITEAGRAFTRNVAMVFDLRMMRNKPETRIFSMTI
>NZ_CP018786.1|WP_079241197.1|1808949_1810317_-|PQQ-dependent-sugar-dehydrogenase
MKKLLFSISIFSSLIVNSQSINLEEFVTGLTSPVEITNANDSRLFVVQQDGIIKIIQPNGTINTTNFLNIGSKITFGGERGLLGLAFHPQYSTNGYFFVYYNNLSGNIIVARYSVSSTDSNVADPASEKILLNIPKPFDNHNGGSIHFAPDGKLWIITGDGGSGGDPNNNAQNKNVLLGKMLRIDVDATGPYNIPPDNPFAGAGVDGADEIWSYGLRNAWKFSFDLTTGNAMIADVGQGAIEEINKMPITTAGLNYGWRCYEGNNAYNTAGCAAQSTMTFPVAVYNHSGGKCSITGGYVYRGNQYPSLQGKYFFADYCSSQIGMLDTNNAITWTTPYSGNNFSTFGEDYQKGLYVADLSNGKIFKISTGTLGTNENTLGTVKVYPNPASKEIFIDGVKDKKATLEIISSEGRKVMETDQIINSKGINISGIPAGVYYINLKSGELKSYSQKLIIK
>NZ_CP018786.1|WP_079241198.1|1810533_1813443_+|protein-translocase-subunit-SecD
MQGKGLITIVAIVLGLICLNELLPTWYASKIEKQATAIAGDNPEKYQKEIARLSKDTLNLGFTKLYYTKAKDKEMKLGLDLKGGINVLLEINQRDLVNDLTNYSTNPVLIEALNKTDEAQKNSTKPYIDNFFEQFDVINKAKGANLKLADPEIFGNTTLTEVKYNTPDEQVKSIVKRKIDASVGTAFEVIRTRIDKLGAIQPNVQRVPGTARISVEMPGMKDIDKVKKMLQTSAKLQFWEVQQVPEIAPYFQTLTTMVATKGDSMGVAKNVNFMSLLQLDKLRTNGVANVKLSDTAVVNKILNSKVGQSLRPSNIKYTQFMWGYKPEATDSESLVLYAIRGNINQKAPVDGAVETANISYDELSRIVVDMQMDSKGAKEWKTLTEKNVGKPVAVTLDNRVYTAPNVVGAIPNGRTQISGNFSQEEAKELVDVLGAGKLPAGAKVVQATVVGPSLGQEAIDSGLMSFIIAFAIIIVYIIFYYGGAGVYAVIAMVINLFYIFGIMDSGDFTLTLPGIAGIVLTMAVAVDTNVIIYERTKEELFAGKSILEAYKDGFKHALNAIIDGHTTTFLTAVVLFFFGTGPIKGFALTLMIGILMTLFTSVLLSRVMIFSRLNKGKGLSVWTPATKNLFRNTWIDFIGKRKYAYIVSAVLTVICVISIATHGFKYGIDFTGGRNYVVRFDKDVKAEDVEEKLVALFKTEDGKNSSVEAKTFGNNKQLKISTDYLIEDESLKADQIIEQKLFEGLKSNLPAGTTLKDFKSADKDHAGIISSEKVGPSVADDIQTHGIYAVLAALAMIFVYILVRFRKWQFSLGAVAALFHDAVIILGAYSLLHKYMPFNMEINQDFIAAILTVLGYSINDTVIIFDRIREYLREKKSLTLAGLFDDSISSTLGRTFNTSFTTILVILAIFIFGGDNLRGFMFAMLIGIGFGTYSSIFIASAIAYDFLKTGKEEEVHGKSTSAKEELASK
>NZ_CP018786.1|WP_079241199.1|1813883_1814456_+|hypothetical-protein
MKTEKLFVAVALCAASFLLAQVGIGTPNPDKSAALDITNTNKGVLIPRISNLSTIVTPANGLLVYDLQRQALTQNIGTPSSPNWVPISGNIVKFFYMPSISIDTSTLGTGRTKDLFQLYKVQFSTPKVSSTGAPGGIPFFANASDLYYYVTDFDNTVLSNVSIDPNGILKYDVVGTATACSFVNIVFVIK
>NZ_CP018786.1|WP_145953226.1|1814538_1815807_+|hypothetical-protein
MMKTISIVRCLLMAIGLFVSGKVISQEMVALPNGGCGRLLDTNTSSSSDGGFLCFRLGKEAANPNNMTDTDVNSFASLKPGTGAGLFCSMYVGVGTSGADFQANKPVYIDFASDGFNFNPSFNGGNFVFYNNGQEVYRTGINGHFFFDFGDNQERRIIKVIPTAAWDEVQLAFGEAIGIGFSFSQMRVYNILSEYYLAPMTYLSQPSDKTVAAGGSTTMTAVINNTPTDETPDNITYQWQVLIGSTWTDLANGSNYANVTSSTLSINNVPAGFHNNQYRVVANSSFHTCSFQAISTVGRLFVNSVNSPGTIAVDQTVCMDISNDPAAFSQTAAAQVSGAAEYQWQSSTDNITFSNITNATSATYDAPPITQTTYYRRGVRSVLNGNTTAYQYSNVVKVTVKQSCLIKCIITNRMIYTTLNSN
>NZ_CP018786.1|WP_079241201.1|1816022_1817276_+|TCR/Tet-family-MFS-transporter
MENSKKKAAIGFIFITLLIDITGWGIIIPVVPKLIEELIHADISEAAKYGGWLGFAYAFTQFIFSPLVGNLSDKYGRRPIILISLFGFAVDYIFLALAPTIWWLFLGRVIAGITGASVTTASAYIADISTDEDRAKNFGLIGAAFGLGFIIGPVLGGVLGHYGARVPFYAAAGLCLLNFLYGYFILPESLDKDKRREFDWKRANPIGSFKFLGKHPEISGLIVSLILIYIAGHAVQSNWSFFTMYKFSWTERMVGISLGVVGLLVGLVQGGLIRYTTPRLGEQKSIYYGLAFYAVGMLLFAFASEGWMMFVFLVPYCLGGICGPALQSVITKSVPSNEQGELQGALTSLMSATSIIGPPMMTNLFYYFTHDEAPFKFSGAPFFLAFVLMAISVVITYSAFQKKNKNLVDVTSKKDFH
>NZ_CP018786.1|WP_079241202.1|1817384_1818188_+|arylamine-N-acetyltransferase
MNTSELEKYFERIHFSGTPELSLETLKRIHQLHPKYIPFENIDSYTGKVPSLNTDDVFRKIVIESRGGYCYEQNLLLSEVLKTLGFNVKLQLGRVVWGRQEDSIAAQTHLLLIVDFDGDQYVVDCGFGTATLTAPILLNKIEQQQTPNGIFKVSHKEETYTLWMWKEQWLPVYRFIPEYVEPIDLDISNWYLSTHPDSHFKNRLILSKVDENARYTYTDHMLNIRSDDGEKESIRIENDVQLYEILINTFGLQENAVEALKSKVRIW

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP018786_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018786_4

2560326-2560428

Orphan

Consensus_repeat	Method
AGTTGGTGGAGTAGTAGGCGGTGTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018786_4

>merge|NZ_CP018786|4|2560326-2560428|CRISPRCasFinder
ACTAGGAGGTGTAGTTGGTGGAGTAGTAGGCGGTGTAGGTACTATCGTTGGAGGTGTTGTTTCTGGCGTAGGATCTACAGTAGGTGGAGTAGTAGGCGGTGTA

>NZ_CP018786|4|4|2560326-2560428|CRISPRCasFinder
ACTAGGAGGTGTAGTTGGTGGAGTA	GTAGGCGGTGTAGGTACTATCGTTGGAGGTGTTGTTTCTGGCGTAGGATCTAC
AGTAGGTGGAGTAGTAGGCGGTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018786.1\|WP_079241769.1\|2554052_2557490_+\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|293739
NZ_CP018786.1\|WP_079241765.1\|2546098_2546668_+\|fasciclin-domain-containing-protein	unknown	unknown	gnl\|CDD\|225214
NZ_CP018786.1\|WP_079241777.1\|2569272_2570511_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079241764.1\|2545469_2545985_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|376583
NZ_CP018786.1\|WP_079241776.1\|2568489_2569173_+\|DUF2625-domain-containing-protein	unknown	unknown	gnl\|CDD\|371310
NZ_CP018786.1\|WP_079241779.1\|2571038_2571374_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
NZ_CP018786.1\|WP_145953236.1\|2565045_2565753_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018786.1\|WP_079241774.1\|2566146_2567304_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225256
NZ_CP018786.1\|WP_079241772.1\|2563404_2564898_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP018786.1\|WP_079241770.1\|2557486_2558722_-\|YaiO-family-outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|275183
NZ_CP018786.1\|WP_079241775.1\|2567381_2568374_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|270702
NZ_CP018786.1\|WP_079241766.1\|2547481_2548297_+\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372666
NZ_CP018786.1\|WP_034697923.1\|2546746_2547457_+\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372666
NZ_CP018786.1\|WP_079241767.1\|2548704_2552613_+\|response-regulator	unknown	unknown	gnl\|CDD\|236848
NZ_CP018786.1\|WP_079243925.1\|2559001_2559787_-\|LexA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP018786.1\|WP_034697917.1\|2552625_2552982_+\|response-regulator	unknown	unknown	gnl\|CDD\|381116
NZ_CP018786.1\|WP_079241768.1\|2552991_2554059_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP018786.1\|WP_079241780.1\|2571467_2572925_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP018786.1\|WP_079241778.1\|2570608_2571016_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP018786.1\|WP_079243926.1\|2560733_2563118_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|366183

Protein	Function_ID	Function_description	E-value
NZ_CP018786.1\|WP_079241769.1\|2554052_2557490_+\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	1.6099e-58
NZ_CP018786.1\|WP_079241765.1\|2546098_2546668_+\|fasciclin-domain-containing-protein	gnl\|CDD\|225214	COG2335, COG2335, Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane].	4.40311e-55
NZ_CP018786.1\|WP_079241764.1\|2545469_2545985_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|376583	pfam01641, SelR, SelR domain. Methionine sulfoxide reduction is an important process, by which cells regulate biological processes and cope with oxidative stress. MsrA, a protein involved in the reduction of methionine sulfoxides in proteins, has been known for four decades and has been extensively characterized with respect to structure and function. However, recent studies revealed that MsrA is only specific for methionine-S-sulfoxides. Because oxidized methionines occur in a mixture of R and S isomers in vivo, it was unclear how stereo-specific MsrA could be responsible for the reduction of all protein methionine sulfoxides. It appears that a second methionine sulfoxide reductase, SelR, evolved that is specific for methionine-R-sulfoxides, the activity that is different but complementary to that of MsrA. Thus, these proteins, working together, could reduce both stereoisomers of methionine sulfoxide. This domain is found both in SelR proteins and fused with the peptide methionine sulfoxide reductase enzymatic domain pfam01625. The domain has two conserved cysteine and histidines. The domain binds both selenium and zinc. The final cysteine is found to be replaced by the rare amino acid selenocysteine in some members of the family. This family has methionine-R-sulfoxide reductase activity.	6.17693e-77
NZ_CP018786.1\|WP_079241776.1\|2568489_2569173_+\|DUF2625-domain-containing-protein	gnl\|CDD\|371310	pfam10946, DUF2625, Protein of unknown function DUF2625. Some members in this family of proteins are annotated as ybfG however currently no function is known.	9.76701e-114
NZ_CP018786.1\|WP_079241779.1\|2571038_2571374_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	1.60398e-21
NZ_CP018786.1\|WP_079241774.1\|2566146_2567304_+\|hypothetical-protein	gnl\|CDD\|225256	COG2382, Fes, Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism].	0.000592016
NZ_CP018786.1\|WP_079241772.1\|2563404_2564898_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.33836e-52
NZ_CP018786.1\|WP_079241770.1\|2557486_2558722_-\|YaiO-family-outer-membrane-beta-barrel-protein	gnl\|CDD\|275183	TIGR04390, hypothetical_protein, outer membrane protein, YaiO family. Members of this family share a domain of bacterial outer membrane beta barrel, up to the protein C-terminal residue (usually Phe or Trp). The member YaiO was shown experimentally to be localized to the outer membrane. [Unknown function, General].	1.76177e-58
NZ_CP018786.1\|WP_079241775.1\|2567381_2568374_+\|phosphotransferase	gnl\|CDD\|270702	cd05153, HomoserineK_II, Type II Homoserine Kinase. This subfamily is composed of unusual homoserine kinases, from a subset of bacteria, which have a Protein Kinase fold. These proteins do not bear any similarity to the GHMP family homoserine kinases present in most bacteria and eukaryotes. Homoserine kinase catalyzes the transfer of the gamma-phosphoryl group from ATP to L-homoserine producing L-homoserine phosphate, an intermediate in the production of the amino acids threonine, methionine, and isoleucine. The Type II homoserine kinase subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	2.60782e-35
NZ_CP018786.1\|WP_079241766.1\|2547481_2548297_+\|ferritin-like-domain-containing-protein	gnl\|CDD\|372666	pfam13668, Ferritin_2, Ferritin-like domain. This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.	1.63899e-39
NZ_CP018786.1\|WP_034697923.1\|2546746_2547457_+\|ferritin-like-domain-containing-protein	gnl\|CDD\|372666	pfam13668, Ferritin_2, Ferritin-like domain. This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.	3.62074e-48
NZ_CP018786.1\|WP_079241767.1\|2548704_2552613_+\|response-regulator	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	2.47235e-139
NZ_CP018786.1\|WP_079243925.1\|2559001_2559787_-\|LexA-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.86237e-13
NZ_CP018786.1\|WP_034697917.1\|2552625_2552982_+\|response-regulator	gnl\|CDD\|381116	cd17574, REC_OmpR, phosphoacceptor receiver (REC) domain of OmpR family response regulators. OmpR-like proteins are one of the most widespread transcriptional regulators. OmpR family members contain REC and winged helix-turn-helix (wHTH) DNA-binding output effector domain. They are involved in the control of environmental stress tolerance (such as the oxidative, osmotic and acid stress response), motility, virulence, outer membrane biogenesis and other processes. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	9.61424e-31
NZ_CP018786.1\|WP_079241768.1\|2552991_2554059_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	1.46528e-05
NZ_CP018786.1\|WP_079241780.1\|2571467_2572925_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.56676e-116
NZ_CP018786.1\|WP_079241778.1\|2570608_2571016_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.26462e-11
NZ_CP018786.1\|WP_079243926.1\|2560733_2563118_+\|TonB-dependent-receptor	gnl\|CDD\|366183	pfam00593, TonB_dep_Rec, TonB dependent receptor. This model now only covers the conserved part of the barrel structure.	6.31255e-20

>NZ_CP018786.1|WP_079243925.1|2559001_2559787_-|LexA-family-transcriptional-regulator
MSVFSNNIRFLRARRKLSQQNVADELLISRVRYSKYENGISEPPIELLVKISKYFHVSIDLMLSVDIEKHPIDEMLKLPDNRIVLPVAVDTHGNDTIEIIPQKASMGYLEGYSDIDYIESLQRIALPFLTNGKYRAFPADGDSMPPFRNGSYIVGKYVEGINELKPGKTYVFVTLNDGITYKRFKERKENAISVSADNSFYEPYDIPFEEVVEIWQYASGIFPEDFEPGDYESYNFKEMFRELRQDIRDLDKKVSGRRRKQ
>NZ_CP018786.1|WP_079241770.1|2557486_2558722_-|YaiO-family-outer-membrane-beta-barrel-protein
MKRYPTFLLALLFPITLYSQQNLTADELFVKARTTAFEQKDYATSIALAKEALEKAPNYTDISVFLGRLYTWNKDVAAARAVFEDLGKREVQDEDYFLAYASLEYWNDQNTKAIEIIDKGLFYHSKSEALLLLKAKVYFGMDNYEEADKAVTTLLSINPKNTEARALAVRIKDLSSKNAVGIIYNYSHFDKQFDDDWHIVGVSYKRITPIGSVILRGNYANKFAQGGTQIELEAYPRLSKMFYLYVGGGYSDDVGLFPKYRTGVSLNANLPHSFEAELGYRQLHFSNSIWMYTAAVGKYYKNFWFNLRTYITPDSKNISHSYTGTVRYYTKGAQDYFAFQIGTGISPEEYRNNLLENETFKLKTFKVGAEYNFSYRSVNLFSIGTMYYNQEFRPGEKGNQFDITLGYTRKF
>NZ_CP018786.1|WP_079241769.1|2554052_2557490_+|sulfatase-like-hydrolase/transferase
MLEFSHIIYEVVIWLFLVYGTAVTLIYGWIGIYALGAVLRYKKENTFTDYSIIAANPNAPVFSVIAPAYNEGMTIVENVRSLLSLYYHNLEIIIVNDGSKDDSIQKLIEAYELESVVYFIQGKIETNAVRGVYKSKNPAFKKLIVVDKENGGKADALNVGVNISSGEYLVCIDVDCILEQDSILKLAKPMLEQTDKKFIACGGVIRLANNCVIENGKVVSVNMPKTLLGRTQALEYIRAFVLGRMAWSRASGLILISGAFGVFDRKIVLACGGYDKSTVGEDMELVVRMRKYMEEKNEPYEVLTIPDPLCWTEVPESKDILRKQRNRWMRGTMETLWKHRKMMFNPKYKKLGMISLPYWFFFEFLGPLIEFSGYIIFIIFLLLGIINWPFFIVLFALVISMGFLYSIYAILVDLVSHQVYTKRKDFFRLIFTAFSEPFYFHPIVVKAGVNGFIDYFKKSHGWGEMTRQGFNQSTQHLPLKERISAILQVGLKKWGMLALVFFALFLIGVTAESLWYKYTFPKFETSAIIGRLFFENILFALQLTFCVGVIYLIINFIKEGWARILGILTLVVVAVTQYILFLYFSESRNVLGADLLYYSKEEMKQILQASGMLNFKNFALLGILITASLVPLWIAGKTALKSIYPGMILLIFGLSAFFIPSNLVGAKVLNSESEFNQNAAKSKWAYFFKSNEDNFISDHPELTELLSDNEDFTANAEMIDKNFPFWRKENTPDFLGSYMNKSEKVPNLVFLVMEGFGHAYTSPKGYIGNFTPYLDSLSNKGLYWENSLSSAGRTFGALPSLTGSLPFGKNGFLEIEKTPENFNLYNILKANGFETGFYYGGHVSFDRYREFLEYSGVDHIVDEASFTIPYRKLPANNGESWGYEDQAVLNKMQQQQKPQNQPYFNMILTLSTHNPFLINNKDYYEKLYNQRLNSGILTKEQKKWAAAHKNQLISVLNADDAMKGFFENYSKRPDFKNTIFVITGDHSMPEITLESKIDRFHVPLLIYSPLLKESKRFHKTVSHFDIAPSILAYYRNNYKITTPSTVTWVGRGFSADAEINKAGIPMMQSKNQLIDFVSEKYYIHDGQLFTLKDMEEDASNDAAAMSKINGRFNQYKSMNAQFYSTKKLMPDSVIVNFKKKTKSKF
>NZ_CP018786.1|WP_079241768.1|2552991_2554059_+|HEAT-repeat-domain-containing-protein
MFLTTSVHFLFLVFLGMLSLVLLLIIVVLIYSFYQYRESVQAFRWSEVINKKISEVIVYGEEEMYADTNFSVASGSPSFRNLFLQKLAESEKKFSGAAQNKLKDLFREYGLQEEALKKLNQKKEHIIAGGIQELTAMHVEEALPKISTFLTHPSAQVYQEAQYAMVNFKGFEGLHFLNSISSRISEWQQLRLLISITHIPEKSGDSIKKWMESSNESVVIFTLKLLRKFQILSLYSTVIDLLNHPSVEVRVQAVQTLLSLENSSTIAHLMEMYPNQPIEVQKEVLKVMKKSKEQCSTDFLKNQLLNNADSGIKVYAAEALCALEQQEYLAEISQKETSSEELIQIIKYALQEKVC
>NZ_CP018786.1|WP_034697917.1|2552625_2552982_+|response-regulator
MLILIAEDDELILKTIEHKLLKEGHEVILTRNGKDAIETLKTRDVDLAITDIMMPFASGIEILSAIKTMGKQVPVIMLSSMGQEEVVLNAFDLGAADFIVKPFSPNELILRIKRFSLK
>NZ_CP018786.1|WP_079241767.1|2548704_2552613_+|response-regulator
MKKYPIPANEEGRMKKLEYFDLLNLEKDPQLDIFAETACLVTDCPAALIAMMESETQTIQSCVGMALDFVDRKNTVCQYSIASGEILIINDTLLDERSSENPLILAGGIRFYAGVPLIDDEGFVLGTICVIDYKPKTITEDQISALKKIGDAITKILTGKRKNIQAEYFQQTFTISNNLICVLGKDFSLKEINPAFENTFQMDKGQILGQNFLDLIGNHNSQLQLLSKNLPNTDEEVTFTTSTKIDDIQTIIIEWYLKLNQNHSEIFCFGINITQRIEEKLKLESSERRFRSFFENAIGLMSMHDMEGNIIAVNEKGRETLQYSVEEVERLNLKDLVPQKNWPLLEQYLERINKNQEDFGTMILRTKGGEDMIWMYHNLVEINKEGNPYVVSTALNVTERITLEKDLVHTKKMLEQTSAVAQVGGWEVNLKNNTVLWSQSTREIHKIDKNFQPDFENALGFYSEKSREKLEFLFEKAIKEGIPYDEELQLVQNDGMMIWVRVKGIPEFEDGVCTRVYGIIQNIDTFKNIYLELAKKEAMLQSFVKYVPSTVAMFDKDLNYVSVSRSWKDEFQMNDIRLIGENMFKISPNVPDERLKIYQDALAGKAYKNEDMAIEVPGKGIIQHYSVEVTPWYLSNNVIGGIIVSAQNITPSVRINRELKNAKKMADIASKAKSEFLANMSHEIRTPLNGVIGFSDLLLKTPLNDIQTQYLNYINESGENLLNIINDILDFSKVESGKMDLIIEKSNIYDMVSQVINVILYQSQKKNIELLLNIEQGLPEIMWLDESRLKQILVNLLGNAVKFTQQGEIELKVEKLNIDNKNIKLRFSVRDTGIGIPKEKQHHIFNAFTQENSSISKTYGGTGLGLTISNNILKYMGSSLSLVSELQKGSVFYFDLEVPYELSDRHEDEDLKISKVLIVDDNEANRIIIQHMLAYKNIDSKLAANGMEALQILLAGERFDVILMDYHMPIISGLETIEKIKELFSKQNESSPLIILHTSSEEHDVINSFRQENNSFFLLKPIKSEELYKTLRRAVKNTEKEVTSIAQPETEDSILMQAPQVLLVDDNPVNMVLNHKMMRSLVPDAHLTEATDGLQAVLQCKEKAFNIILMDVQMPVMDGIEATKQIRLLPEYSNVPIIGVTAGNVLGEKEKCLDSGMNDFLPKPLRQADLLEMLKKYIINESNNPAEDSSHQENYLDINLLNEQIGDDDEDFRKIFLNLVIEQLNQAEENIKKSTAEKDSDHLKLILHKLKGTAGTAGLVKLTERTASWEKKAETNMDFMSMEEEIIREITTGLQLIKNLIQ
>NZ_CP018786.1|WP_079241766.1|2547481_2548297_+|ferritin-like-domain-containing-protein
MNILRLLDKLSDDKFFTSEASRLETITNISLFGKKAATAAVPLGLGAMMATPAKAEAPKAKLTGMALKSTLTDALQLALVLEYLENEYYSIGLSTPGLIPNGDRTVFMQISKHESAHVSFLKSTLTSLGTTPGNKPTFDFTAGGNFMPFIDYNQFLILAQAFEDTGVRAYKGQAGNVMSNKVVLQAALQIHSVEARHASQVRRMRANKGWIELANGGSMPSATNPVYAGEDNTNQAGYNTATLFGAAAGSAAYDEILSGSDAQAIASLFIV
>NZ_CP018786.1|WP_034697923.1|2546746_2547457_+|ferritin-like-domain-containing-protein
MKKPIQVSNQGATLDTSRRNFLKLGGVGLAIAGLTIIGCNDDDDFQIIEESKYDLGTGDVGVLNYAYALEQLEADFYTKVVNNFYTGISSIEKEVFTDLYHHEVIHRDFFKVAISGATDHVLPKLEFQYPNVNFNDRNSVLATAKALEDTGVAAYNGAGKYISNPAYLVIAGKIVSVEARHASAIRNLINPGSADFSGDDVIDANGLDLAKEPKDIVMAAGAFIKTPFTWKERGIN
>NZ_CP018786.1|WP_079241765.1|2546098_2546668_+|fasciclin-domain-containing-protein
MNTHSKITVLAMVALSFAFSGKVTAQTMKEKTVMVGGAPMYPSKNIIENAVNSKDHKTLVAAVKAAGLVETLQGAGPFTVLAPTDAAFAKLPKGTVENLVKPENKAMLTSILTYHVLPGRYSAKEIWTAVKAGNGKSMMKTVQGENLTFWTKGKDLYIKDAKGNSAKVTIADVNQSNGVIHVIDTVLMP
>NZ_CP018786.1|WP_079241764.1|2545469_2545985_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKTPFSKTILAFCVVLSFGTYHAQSTLFKSKNPYYSHTAQNTLKVSNNEWKKILKPELYQVAREGATETAFTGKYYEFDEKGTYYCAVCGNPLFISTSKFATTCGWPSFYQPIGKKSVKYRKDTSYHMERTEVLCGRCDSHLGHVFDDGPKPTGKRFCMNSICLEFIPNKK
>NZ_CP018786.1|WP_079243926.1|2560733_2563118_+|TonB-dependent-receptor
MKRTVYFLVGGTLMYSPSLLKAQKITPEKKIVKDIESVQVQGKSNYNTVNISRKKLDFIQSNTLGETLSKIPGIQNSGYGPNSGAPVIRSLSGNRVKILENGTAVNDLSGISPDFNTDIEMNNVQNITVYKNSASVLYGGKAIGGALDIETDYIVRQLPDKKFNVKGLLEGGSNSGQKQAFSAKGVIAKNWVWTVGASNQKQEMVRIPGKSKDSRCYDPNLVGFNSILQSLCQIDVNSRRVLNKSLFPYISQFAKDHMIEYELSEDDLYTFSSTYYNPADGKYYPNPKNDLYVPGQDAVKDRYKSEVNGIKDYVETKDGVIPNSHSESNSFYVGTSYIGKSLYVGGAYQNSYSYFGVPGYAIPKIPKHSHGKPQPKIEYSPINIRSLSHKAMFESGYKFTHFPISSIKLNYMGVFSKNAELLDRYRANQFAINQHNSRLEITQQKLRFLTGTTGLEVQYRDMEGTGGQKYLPNTISREIGVFTMQHLDFNIIQFDLGYRNDHVQRRAEADNKYVRSRGLSGGKLSDRDFTLHQFHSSAQWTLFKKGYLKVQYNHSERAPEVNELYSGNNHFAILTEENGDDRLDKETANTVEIGGGLNLKNFRVSASWYNTSYKNYIYLAHTGISREIFLVKEWRSDDTEINGIEAEASYKADLGKIGKWEIGGYYDLVRNISVADSSIRKWSDGDYMPNMPTSRFGFSLEGNVQNFSMNVSLDHYLKQKYLGKNINPELPMPAFSLLNVRLAYKDNSLGIGDLEYYIIGNNLLNTEARLQNSQLKFLSPLPGINISAGVKITI
>NZ_CP018786.1|WP_079241772.1|2563404_2564898_+|BspA-family-leucine-rich-repeat-surface-protein
MCKKQLIIIFLLLFCISYAQNEFTTIWKPNANGIIDHSIRFGGTGTDYTIHWEEVGYPEHNGMFDYVTSSSNEPLLIYFGPSFHPDPLQATYQLKVFSGNGLFYGFRANTDMVPPGGNQELIELSQWGNTTWLQQFDRAFANCPNLNVTAADGPDLTQITSLSQMFLNCSSLTGHTSFSYWNPYNVTDMSGMFSGATLFNQNIANWYTAKVTNFSSMFSSASSFNQDISAWNTISGTDFSSMFADATAFNQPLNSWNTENATNFRYTFYNAAAFNQPLDNWNTGKVTDFEHMFENAVSFNQPIGNWDVSKIDYFAGFNMFAGASNFDQDISSWNIKLQNFSWNSIYLGFKNVGLSCTNYSNFLIALNNNPTWANSTITSGTIDATGLVYSTPQAMLARAQLINKGFNIIGDSYISGCYLSTREASPKTKTSAYPNPTTGVINVESSVDENVYLYDNNGNLIKNILFRKGKNTIDLTEYPAGDYIFKGDTFFNKITKQ
>NZ_CP018786.1|WP_145953236.1|2565045_2565753_+|hypothetical-protein
MKKTITFFTILLSIVHIQAQENINLLTYENTQDINFFNTIKNGAQVKEYLTTSKNSVKVGDTLILGSPTSEELNTRTYSGSYGNKARGGISQSRSTSKKTYEFIQMGRPAGFGSIMSAMGGEAQNMADNSLKNTKVIVREIKTYHRGSKNKPLYVVMVLGEINDRAFGINKYLSVMDTELGIESGEILLKNRKMTRDEAIAKLKEAKELVEIDMMSKEKFEELKKELAPIINNNN
>NZ_CP018786.1|WP_079241774.1|2566146_2567304_+|hypothetical-protein
MIKKYLLFLLIFTSATSSLLAQNYERYKILKDTILKSTSLGFEKKISVMVPIEWQKKSGNKFPLIIIFDRQNKRSNHYILNTIDYLTSNEQIPSSIIISVESEQRYRYLETQYKISDPNGLALENEKFIFEQLIPLAEREYKASAFRVLIGHSRYGYFTTSLWNSRINDLNAIISMSPFFTQKNVDLTDSISQFNKRSFRTKKYYRFGIGNDYPEDFMKMDSIIKKINNPFLDMKGYEFKKADHNATPGLLINTALYEIFEDWSAIQSKYISNKQTDLSIKSLLDKEIRSNYGVNLNFSLGILNGKGWAFYNEKQYDKALQAWKILTDSYPNFSEAYLNIIKAKILLHQDYSATVKEFNISLANSEFYKEKEKKDLEVELQEIVK
>NZ_CP018786.1|WP_079241775.1|2567381_2568374_+|phosphotransferase
MTEKFPTINSTLSPDRLGQLIQEKYGFTDKTECSIFRLAMNHLYIVHDGENKYVFRVYTHHWRTELEIQEELRLLNHLKEADRQVAFPIADQSNKFIQEIEAPEGTRFGVLFSYAKGIKTAKFSPETSFLIGKALAKVHQSTEHVELMRMSYNSQNLLKNPVIRTKNFYSKNTAEIEFLENVSDFLTLKMEKADQQNMRYGAVHLDVWFDNLHIDNEEKITFFDFDFCGNGYLCFDISYFLFQLFTTHLNQEEYEAKADHFIRGYETVTKISHEEKQFLPYACLAIMNYYISVQCDRFEYWTNIFLNEDHLKRMVGNLKRWIAYHKIEVK
>NZ_CP018786.1|WP_079241776.1|2568489_2569173_+|DUF2625-domain-containing-protein
MRSIDELINDKDPGWILVKEWIDTAKNKVEILPVDSNKAKDALYKTQVTTKSPMGSIVYMTGGLLVDNGWIRILGSGSEKLRRSLPEWNRGKTFEDYGQPIPYLLIADDAIGGIFILNGGGLGNDLGKVYYLAPDNLEYEPLDITYTEFLNFCFNKNLDEFYKEYRWANWKKDVAKLKGDQVFSFFPYLWTEQGKDISKGSKKEVPIEESYKLTLEFRKKLGFDTEK
>NZ_CP018786.1|WP_079241777.1|2569272_2570511_+|hypothetical-protein
MDTKPISFPNQRKHNTVLRFLHLFVISYVYLFIFTSQFSPLAGIYKSGVLWLCKNVFQQTQVEYIIMTGSGDTTLDYWVVIVNIGLALVAALIILLADKKQRTFKDLHWFTVVVARYYVAMIMLSYGFAKLHDGQFPPNSIGRLEEKVGDMSPMGMVWTMMGASTGYTFVSGLLEVMGGLLLLFRRTKTFGALFSMTVMINVALLNFFYDVPVKIFSSHIVLFCLFIVSGDAMALYRFFILHQPSQLRFQKRTFDKKWKSITVIVFKWLVVAFFILSSSSALFYTPPAAPMEGAYIVDKFIINNQEIPCNDSIGWKKILISSPSRAKVILNNDSTKTFQSVVDTEKKTLMLRKTDHQELYAYLHYNTQKDSIIFTGNKGRDSVKIKTIKKKKEDYPLNKRSFHWINEYPFNR
>NZ_CP018786.1|WP_079241778.1|2570608_2571016_-|GNAT-family-N-acetyltransferase
MITYQIEEKIGIEEFIQVLENSTLGERRPINEPERITEMLQHANLIATARDNGKLIGISRSLTDFAFCTYLSDLAVDENYQKKGIGKELIRLTKEHTPKATLILLAAPKAVGYYPKIGMKQWEQCYILNNVENLK
>NZ_CP018786.1|WP_079241779.1|2571038_2571374_-|antibiotic-biosynthesis-monooxygenase
MIAVIFEVVPEEGKKDEYLNIARSLKSELEMIPGFISIERFQSLVDPKKILSLSFWEDEYSIKEWRNRTTHRKAQQAGRNSVFEDYRLRVASVIRDYGMSERQEAPTDNIF
>NZ_CP018786.1|WP_079241780.1|2571467_2572925_+|PLP-dependent-aminotransferase-family-protein
MFPFEHIINIDKEKKLPVYRQIAISIINTIRNGNLKAGMALPGTRELAKTLGVHRKTVIAAYEELNAQDWILIIPRKQVRVSEHIPTLQPQKWNAQDSSVSYENNFDLPLHISKKDPSLQELTVLPEVFIDDGHPDIRLSPIDELLKIYRSYTSRSFSIKKAVVGTTQGTLKLREELSRYLSVTRGLNISADNLLITHGAQMSIYLAAQLLLQAEDIIICGKPGYPIANSAFEKTKASVIEIPVDENGLDINALEKICKKKKITAVYLIPHHHYPTTVTLSVERRMKLLELSNQYSFAIIEDDYDYDYHYSSSPYLPLASGAHKGNVIYIGSFSKILGSSIRIGFMVAPKNFIQEAVVLRKAIDVGGDGYMQNALAELIKSGDLGRYLKKAKKSYHQRRDYLNILLQQHLSPYISFTLPDGGLSVWLQLKDSYSVNTLKTHPQLKIKQIDEKENAFRLGFASKNEKELEDAVLLIKKILTNSYSI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018786_1	1.1\|279137\|26\|NZ_CP018786\|CRISPRCasFinder	279137-279162	26	KX017520	Salmonella phage 64795_sal3, complete genome	38515-38540	4	0.846
NZ_CP018786_1	1.1\|279137\|26\|NZ_CP018786\|CRISPRCasFinder	279137-279162	26	HG796800	Uncultured bacterium plasmid pRGF00059	2037-2062	5	0.808

1. spacer 1.1|279137|26|NZ_CP018786|CRISPRCasFinder matches to KX017520 (Salmonella phage 64795_sal3, complete genome) position: , mismatch: 4, identity: 0.846

agcatcgttaatgggagaaaatatat	CRISPR spacer
tgcatggttaatgggaaaaaatatag	Protospacer
 **** **********.********

2. spacer 1.1|279137|26|NZ_CP018786|CRISPRCasFinder matches to HG796800 (Uncultured bacterium plasmid pRGF00059) position: , mismatch: 5, identity: 0.808

agcatcgttaatgggagaaaatatat	CRISPR spacer
taaatctttaatgggaaaaaatatat	Protospacer
 . *** *********.*********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1823608 : 1834806

Staphylococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079241208.1\|1823608_1824787_-	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	9.6e-69	42.2
WP_034696272.1\|1824789_1827000_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	1.3e-13	37.7
WP_079241209.1\|1827109_1827475_-	hypothetical protein	NA	NA	NA	NA
WP_079241210.1\|1827731_1829639_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	5.9e-84	39.6
WP_079241211.1\|1829691_1831590_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	3.7e-62	32.0
WP_079241212.1\|1831734_1832094_-	response regulator	W8CYM9	Bacillus_phage	4.7e-11	31.9
WP_167595413.1\|1832103_1834806_-	sodium:proline symporter	W8CYF6	Bacillus_phage	1.3e-20	29.6

DBSCAN-SWA_2

3180703 : 3260591

uncultured_phage(22.22%)

tail,protease,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079242249.1\|3180703_3181192_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_079242250.1\|3181349_3187265_-	hypothetical protein	NA	NA	NA	NA
WP_079242251.1\|3187283_3188039_+	hypothetical protein	NA	NA	NA	NA
WP_079242252.1\|3188042_3189122_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_079242253.1\|3189259_3189628_+	four helix bundle protein	NA	NA	NA	NA
WP_079242254.1\|3189687_3189981_+	hypothetical protein	NA	NA	NA	NA
WP_157885754.1\|3190084_3190252_+	hypothetical protein	NA	NA	NA	NA
WP_079242255.1\|3190301_3192332_-	recombinase	NA	NA	NA	NA
WP_079242256.1\|3192345_3192990_-	monofunctional biosynthetic peptidoglycan transglycosylase	NA	NA	NA	NA
WP_079243953.1\|3193033_3193951_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_145953256.1\|3194517_3194880_-	nucleoside-diphosphate sugar epimerase	NA	NA	NA	NA
WP_158521370.1\|3195500_3199028_+	discoidin domain-containing protein	NA	NA	NA	NA
WP_079242261.1\|3199485_3200763_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_079242262.1\|3200886_3203433_-	DNA ligase D	A0A291AUP8	Sinorhizobium_phage	4.8e-41	33.8
WP_079242263.1\|3203481_3204261_-	Ku protein	A0A218M9C0	Mycobacterium_phage	2.9e-29	31.4
WP_145953257.1\|3204367_3204982_-	hypothetical protein	NA	NA	NA	NA
WP_185116995.1\|3204993_3205368_-	hypothetical protein	NA	NA	NA	NA
WP_079242265.1\|3205444_3206089_-	response regulator transcription factor	NA	NA	NA	NA
WP_079242266.1\|3206088_3206823_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_079242267.1\|3207565_3208999_-	hypothetical protein	NA	NA	NA	NA
WP_079243954.1\|3209009_3211769_-	hypothetical protein	NA	NA	NA	NA
WP_079243955.1\|3211823_3212549_-	Fn3-like domain-containing protein	NA	NA	NA	NA
WP_079242268.1\|3212705_3213251_-	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_079242269.1\|3213469_3214015_-	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_079242269.1\|3214353_3214899_-	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_079242269.1\|3215237_3215783_-	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_079242270.1\|3215987_3216530_-	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_145953258.1\|3216692_3217103_-	hypothetical protein	NA	NA	NA	NA
WP_079242272.1\|3217476_3221970_-	hypothetical protein	NA	NA	NA	NA
WP_079242273.1\|3221969_3222989_-	hypothetical protein	NA	NA	NA	NA
WP_079242274.1\|3223003_3223846_-	hypothetical protein	D5GVU2	Campylobacter_virus	4.1e-05	33.6
WP_079242275.1\|3224172_3224613_-	lysozyme	I2GUG4	Acinetobacter_phage	1.8e-20	42.7
WP_079242276.1\|3224609_3225179_-	hypothetical protein	NA	NA	NA	NA
WP_079242277.1\|3225255_3226572_-	ATP-binding protein	Q677Q6	Lymphocystis_disease_virus	2.7e-11	29.6
WP_145953259.1\|3226682_3226901_+	hypothetical protein	NA	NA	NA	NA
WP_079242279.1\|3227202_3228060_-	hypothetical protein	NA	NA	NA	NA
WP_079242280.1\|3228311_3230594_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_079242281.1\|3230671_3231529_-	hypothetical protein	NA	NA	NA	NA
WP_079242282.1\|3231880_3232288_-	hypothetical protein	NA	NA	NA	NA
WP_079242283.1\|3232696_3233164_-	hypothetical protein	NA	NA	NA	NA
WP_079242285.1\|3233209_3237502_-	hypothetical protein	NA	NA	NA	NA
WP_145953260.1\|3237809_3238181_-	hypothetical protein	NA	NA	NA	NA
WP_156106585.1\|3238248_3238416_-	hypothetical protein	NA	NA	NA	NA
WP_079242288.1\|3239726_3240389_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_145953261.1\|3240465_3241371_-	hypothetical protein	NA	NA	NA	NA
WP_079242291.1\|3241485_3245013_-	hypothetical protein	NA	NA	NA	NA
WP_079242299.1\|3245098_3248101_-	PKD domain-containing protein	NA	NA	NA	NA
WP_079242300.1\|3248090_3250955_-	hypothetical protein	NA	NA	NA	NA
WP_079242302.1\|3250979_3254030_-\|plate	baseplate J/gp47 family protein	NA	NA	NA	NA
WP_034699502.1\|3254119_3254530_-	GPW/gp25 family protein	A0A0M3LQ08	Mannheimia_phage	2.6e-05	30.7
WP_099049848.1\|3254685_3254979_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_079242304.1\|3254981_3256727_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_099049849.1\|3256728_3257466_-	hypothetical protein	NA	NA	NA	NA
WP_167595394.1\|3257462_3257624_-	hypothetical protein	NA	NA	NA	NA
WP_047388278.1\|3257825_3258293_-\|tail	phage tail protein	NA	NA	NA	NA
WP_034699490.1\|3258295_3258727_-\|tail	phage tail protein	A0A059XEM3	uncultured_phage	5.3e-25	46.7
WP_079242307.1\|3258762_3260136_-\|tail	phage tail sheath family protein	H6WFT7	Cyanophage	5.5e-07	25.3
WP_034699490.1\|3260159_3260591_-\|tail	phage tail protein	A0A059XEM3	uncultured_phage	5.3e-25	46.7

DBSCAN-SWA_3

3620663 : 3634183

Riemerella_phage(75.0%)

capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_145953276.1\|3620663_3621680_-	hypothetical protein	F5A3A0	Riemerella_phage	1.1e-33	31.5
WP_079242588.1\|3621670_3622144_-	hypothetical protein	NA	NA	NA	NA
WP_079242589.1\|3622143_3626952_-	hypothetical protein	F5A3A4	Riemerella_phage	1.0e-100	23.7
WP_079242590.1\|3626958_3627183_-	hypothetical protein	F5A3A9	Riemerella_phage	1.7e-11	52.2
WP_079242591.1\|3627188_3627680_-	hypothetical protein	NA	NA	NA	NA
WP_079242592.1\|3627744_3628254_-	hypothetical protein	F5A3B1	Riemerella_phage	3.5e-36	46.4
WP_079242593.1\|3628265_3628673_-	hypothetical protein	NA	NA	NA	NA
WP_079242594.1\|3628669_3629119_-	hypothetical protein	F5A3B3	Riemerella_phage	2.6e-22	40.7
WP_079242595.1\|3629109_3629433_-	hypothetical protein	NA	NA	NA	NA
WP_145953277.1\|3629433_3629757_-	hypothetical protein	F5A3B5	Riemerella_phage	2.5e-19	42.1
WP_079242597.1\|3629760_3630975_-\|capsid	major capsid protein	M4ZR32	Bacillus_phage	3.5e-13	23.6
WP_079242598.1\|3630985_3631327_-	hypothetical protein	NA	NA	NA	NA
WP_145953278.1\|3631344_3632001_-	hypothetical protein	NA	NA	NA	NA
WP_002984522.1\|3632060_3632330_+	hypothetical protein	NA	NA	NA	NA
WP_079242600.1\|3632314_3632602_+	hypothetical protein	NA	NA	NA	NA
WP_079242601.1\|3632686_3632950_+	hypothetical protein	NA	NA	NA	NA
WP_158521375.1\|3632982_3633135_+	hypothetical protein	NA	NA	NA	NA
WP_079242602.1\|3633134_3633524_+	hypothetical protein	NA	NA	NA	NA
WP_079242603.1\|3633587_3633815_+	hypothetical protein	NA	NA	NA	NA
WP_099049854.1\|3633925_3634183_+	hypothetical protein	A0A2K9VCD6	Lactobacillus_phage	7.1e-09	40.2

DBSCAN-SWA_4

3887485 : 3895852

Pelagibacter_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079242813.1\|3887485_3888277_-	NAD(+) synthase	M1IPF8	Pelagibacter_phage	1.4e-60	52.2
WP_099049859.1\|3888290_3888824_-	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	5.7e-37	47.4
WP_079242814.1\|3888820_3889357_-	GNAT family N-acetyltransferase	G9BWD5	Planktothrix_phage	1.4e-14	34.3
WP_079242815.1\|3889363_3890002_-	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_185116997.1\|3890054_3891041_+	gliding motility protein GldB	NA	NA	NA	NA
WP_079242817.1\|3891118_3892021_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.2e-40	44.8
WP_079242818.1\|3892027_3894229_+	redoxin domain-containing protein	A0A1J0GW78	Streptomyces_phage	8.2e-05	38.2
WP_034695059.1\|3894260_3894584_+	gliding motility protein GldC	NA	NA	NA	NA
WP_079242819.1\|3894712_3895852_+	cystathionine gamma-synthase	A0A0B5JD48	Pandoravirus	1.3e-25	33.8

DBSCAN-SWA_5

5110249 : 5115890

Cellulophaga_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079243661.1\|5110249_5110978_-	serine/threonine protein phosphatase	S0A0Y6	Cellulophaga_phage	5.4e-46	39.2
WP_079243662.1\|5110979_5111522_-	RNA 2'-phosphotransferase	A0A2R2ZGT8	Clostridioides_phage	1.3e-44	51.1
WP_079243663.1\|5111532_5112474_-	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	7.3e-43	35.0
WP_079243664.1\|5112473_5113160_-	NAD-dependent deacylase	R9TG77	Vibrio_phage	2.1e-31	40.9
WP_079243665.1\|5113156_5113741_-	hypothetical protein	NA	NA	NA	NA
WP_079243666.1\|5113737_5114247_-	O-acetyl-ADP-ribose deacetylase	A0A0K1L687	Scale_drop_disease_virus	1.8e-32	52.8
WP_079243667.1\|5114243_5114879_-	DUF4291 domain-containing protein	NA	NA	NA	NA
WP_079244025.1\|5115419_5115890_-	macro domain-containing protein	A0A2L1IVW3	Streptomyces_phage	3.7e-32	44.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018786

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection