CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020063	Klebsiella pneumoniae strain AR_0117 plasmid unitig_2, complete sequence	0 crisprs	DEDDh	0	0	3	0
NZ_CP020065	Klebsiella pneumoniae strain AR_0117 plasmid unitig_4, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP020062	Klebsiella pneumoniae strain AR_0117 plasmid unitig_1, complete sequence	0 crisprs	cas3,RT	0	0	5	0
NZ_CP020064	Klebsiella pneumoniae strain AR_0117 plasmid unitig_3, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP020061	Klebsiella pneumoniae strain AR_0117, complete genome	4 crisprs	cas3,csa3,DEDDh,DinG,cas8e,cse2gr11,cas6e,cas7,cas5,cas1,cas2,RT,WYL	1	8	7	3
NZ_CP020066	Klebsiella pneumoniae strain AR_0117 plasmid unitig_5, complete sequence	0 crisprs	NA	0	0	1	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 22233

Salmonella_phage(91.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014342074.1\|102_315_+	hypothetical protein	J9Q7S8	Salmonella_phage	4.3e-28	80.0
WP_021313779.1\|766_1864_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	2.1e-73	49.7
WP_023279495.1\|2185_2830_+	hypothetical protein	J9Q739	Salmonella_phage	2.2e-99	80.7
WP_021313777.1\|2905_3400_+	GNAT family N-acetyltransferase	J9Q6J3	Salmonella_phage	1.0e-59	67.1
WP_080031176.1\|3588_4674_+	exonuclease	J9Q7S9	Salmonella_phage	1.4e-183	84.5
WP_049594367.1\|4903_6820_+	AAA family ATPase	J9Q741	Salmonella_phage	9.5e-300	84.6
WP_080031177.1\|6809_7556_+	hypothetical protein	J9Q6J5	Salmonella_phage	3.8e-79	61.3
WP_021313773.1\|7565_8135_+	hypothetical protein	J9Q7Z7	Salmonella_phage	1.1e-94	89.9
WP_080031178.1\|8210_10514_+	ribonucleoside-diphosphate reductase subunit alpha	J9Q7T0	Salmonella_phage	0.0e+00	90.8
WP_014342181.1\|10644_11787_+	ribonucleotide-diphosphate reductase subunit beta	J9Q7H3	Salmonella_phage	9.0e-213	95.8
WP_014342179.1\|12932_14036_+	thymidylate synthase	J9Q6J6	Salmonella_phage	2.5e-180	79.8
WP_019704560.1\|14037_14451_+	hypothetical protein	J9Q7Z8	Salmonella_phage	2.3e-54	76.6
WP_032734165.1\|14447_14924_+	dihydrofolate reductase	J9Q7T1	Salmonella_phage	6.4e-72	79.6
WP_080031179.1\|14923_15568_+	AAA family ATPase	J9Q7H4	Salmonella_phage	3.1e-93	77.1
WP_046882083.1\|15631_16051_+	hypothetical protein	J9Q743	Salmonella_phage	3.8e-52	74.1
WP_014342174.1\|16060_16618_+	3'-5' exonuclease	J9Q6J8	Salmonella_phage	1.4e-86	84.2
WP_032440505.1\|16743_17577_+	hypothetical protein	J9Q7Z9	Salmonella_phage	1.3e-64	56.7
WP_023279507.1\|17762_18356_+	phage N-6-adenine-methyltransferase	J9Q7T2	Salmonella_phage	5.9e-99	85.3
WP_032423059.1\|18553_18781_+	hypothetical protein	J9Q7H5	Salmonella_phage	7.6e-31	84.0
WP_032440503.1\|19360_19954_+	ribonuclease HI	J9Q745	Salmonella_phage	1.0e-90	80.1
WP_032734169.1\|20106_20646_+	hypothetical protein	J9Q6J9	Salmonella_phage	1.7e-28	46.5
WP_019704567.1\|20946_21372_+	tellurite/colicin resistance protein	Q71TK7	Escherichia_phage	9.8e-56	80.9
WP_014342167.1\|21371_21527_+	hypothetical protein	H6WZJ7	Escherichia_phage	1.7e-05	61.2
WP_064184673.1\|21654_22233_+	hypothetical protein	J9Q7H6	Salmonella_phage	1.7e-55	57.5

DBSCAN-SWA_2

25801 : 87258

Salmonella_phage(89.29%)

tail,terminase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009310015.1\|25801_27334_+\|transposase	IS3-like element ISKpn38 family transposase	A0A1B1P773	Bacillus_phage	4.1e-51	39.8
WP_080031182.1\|27516_27834_+	hypothetical protein	J9Q750	Salmonella_phage	4.6e-42	74.3
WP_080031183.1\|27916_28753_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_032734115.1\|28825_29341_+	hypothetical protein	NA	NA	NA	NA
WP_048333204.1\|30926_31145_+	hypothetical protein	J9Q6K7	Salmonella_phage	1.1e-26	80.6
WP_080031185.1\|31157_31370_+	hypothetical protein	J9Q804	Salmonella_phage	1.2e-25	74.3
WP_080031186.1\|31506_31818_+	hypothetical protein	J9Q7T7	Salmonella_phage	2.0e-29	66.0
WP_004109918.1\|31937_32345_+	hypothetical protein	Q6UAS0	Klebsiella_phage	2.8e-23	45.0
WP_080031187.1\|32471_32753_+	ABC transporter	J9Q753	Salmonella_phage	6.9e-42	83.9
WP_064165120.1\|32957_33440_+	hypothetical protein	J9Q805	Salmonella_phage	9.4e-71	78.1
WP_004109904.1\|34019_34223_-	hypothetical protein	J9Q7I3	Salmonella_phage	4.1e-28	95.5
WP_004109892.1\|34273_34924_-	hypothetical protein	J9Q754	Salmonella_phage	8.4e-107	91.7
WP_123827665.1\|35248_35548_-	hypothetical protein	NA	NA	NA	NA
WP_014342147.1\|35557_36088_-	transcriptional regulator	J9Q6L0	Salmonella_phage	3.5e-71	84.5
WP_004109889.1\|36243_36681_+	hypothetical protein	A0A1V0E8D6	Vibrio_phage	9.5e-14	37.0
WP_004109887.1\|36731_37007_-	hypothetical protein	J9Q7T9	Salmonella_phage	3.1e-26	68.1
WP_080031188.1\|37009_38569_-	DEAD/DEAH box helicase	J9Q7I4	Salmonella_phage	2.4e-277	91.9
WP_032734124.1\|38652_39333_+	chromosome partitioning protein ParB	J9Q756	Salmonella_phage	2.1e-108	89.7
WP_023279438.1\|39332_40001_+	hypothetical protein	J9Q6L1	Salmonella_phage	6.6e-107	91.9
WP_032423019.1\|39997_40639_+	ATP-binding cassette domain-containing protein	J9Q807	Salmonella_phage	6.8e-109	96.7
WP_064184678.1\|40628_41180_+	hypothetical protein	NA	NA	NA	NA
WP_004109872.1\|41176_42067_+	hypothetical protein	J9Q7I6	Salmonella_phage	5.4e-165	97.0
WP_004109869.1\|42076_42343_+	hypothetical protein	J9Q757	Salmonella_phage	1.3e-37	90.9
WP_004109866.1\|42518_43160_+	DNA-binding protein	J9Q6D4	Salmonella_phage	5.0e-96	88.2
WP_004109863.1\|43162_44419_+\|terminase	terminase	J9Q7Y2	Salmonella_phage	9.4e-248	97.4
WP_026005939.1\|44436_46026_+	hypothetical protein	J9Q7R1	Salmonella_phage	2.3e-275	88.7
WP_023279435.1\|46048_46948_+	hypothetical protein	J9Q7F4	Salmonella_phage	6.1e-124	82.6
WP_004109857.1\|46974_47853_+	hypothetical protein	J9Q710	Salmonella_phage	4.7e-153	94.2
WP_023279434.1\|47931_48360_+	Ig domain-containing protein	J9Q6D6	Salmonella_phage	1.8e-28	70.6
WP_023279433.1\|48407_48842_+	hypothetical protein	J9Q7Y3	Salmonella_phage	2.9e-63	84.0
WP_023279432.1\|48841_49675_+	hypothetical protein	J9Q7R2	Salmonella_phage	2.4e-130	83.4
WP_004109848.1\|49772_50117_+	hypothetical protein	J9Q7F6	Salmonella_phage	7.4e-54	92.1
WP_021313126.1\|50107_50581_+	hypothetical protein	J9Q711	Salmonella_phage	1.9e-76	93.6
WP_047066294.1\|50582_50975_+	hypothetical protein	J9Q6D8	Salmonella_phage	2.0e-47	68.3
WP_023279430.1\|51042_51789_+	Ig domain-containing protein	J9Q7Y4	Salmonella_phage	8.1e-106	82.6
WP_004109835.1\|51850_52168_+	hypothetical protein	J9Q7R3	Salmonella_phage	1.8e-46	93.3
WP_004109830.1\|52284_52518_+	hypothetical protein	J9Q7F7	Salmonella_phage	3.4e-34	93.5
WP_080031189.1\|52525_57061_+	tape measure protein	J9Q712	Salmonella_phage	0.0e+00	70.2
WP_004109823.1\|57104_57440_+\|tail	tail protein	J9Q6E1	Salmonella_phage	3.4e-51	84.5
WP_004109820.1\|57526_58225_+\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	1.2e-122	87.4
WP_004109817.1\|58217_59015_+\|tail	tail protein	J9Q7R4	Salmonella_phage	5.4e-140	85.3
WP_019704527.1\|59002_59614_+\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	1.1e-76	72.1
WP_080031190.1\|59630_71768_+	DUF1983 domain-containing protein	J9Q713	Salmonella_phage	2.4e-29	57.5
WP_080031191.1\|71820_73266_+\|tail	tail fiber domain-containing protein	A0A0H4TGH1	Klebsiella_phage	8.0e-41	38.6
WP_004109805.1\|73356_73680_+	hypothetical protein	J9Q6E7	Salmonella_phage	2.3e-49	95.3
WP_021313119.1\|73693_74386_+	structural protein P5	J9Q7Y7	Salmonella_phage	4.1e-120	89.6
WP_021313118.1\|74388_74640_+	hypothetical protein	J9Q7R6	Salmonella_phage	5.8e-24	72.3
WP_032734133.1\|75056_75449_+	hypothetical protein	A0A077SLR3	Escherichia_phage	1.0e-14	42.2
WP_060598465.1\|75433_76183_+	hypothetical protein	J9Q7Y8	Salmonella_phage	2.7e-16	31.3
WP_021313115.1\|76367_77033_+	P-loop NTPase	J9Q7R7	Salmonella_phage	2.9e-102	83.7
WP_004110193.1\|77032_77395_+	hypothetical protein	J9Q7G3	Salmonella_phage	1.2e-43	97.9
WP_135710443.1\|77436_79155_+	hypothetical protein	X2KLG0	Campylobacter_phage	7.1e-12	27.2
WP_023279420.1\|79328_80054_+	hypothetical protein	J9Q7R8	Salmonella_phage	2.5e-128	88.8
WP_014342110.1\|80118_81459_+	AAA family ATPase	J9Q7G4	Salmonella_phage	7.0e-241	95.7
WP_080031193.1\|81612_82731_+	DNA primase	J9Q720	Salmonella_phage	1.6e-201	90.8
WP_080031194.1\|82770_83937_-	hypothetical protein	NA	NA	NA	NA
WP_080031195.1\|84225_85014_+	hypothetical protein	J9Q7Z0	Salmonella_phage	1.4e-71	51.1
WP_023279474.1\|85093_85561_+	hypothetical protein	J9Q7R9	Salmonella_phage	1.3e-48	63.9
WP_064406281.1\|85560_86883_+	DNA ligase	J9Q7G5	Salmonella_phage	1.9e-227	85.5
WP_040170975.1\|86882_87059_+	hypothetical protein	J9Q729	Salmonella_phage	2.0e-15	74.5
WP_049594359.1\|87042_87258_+	hypothetical protein	J9Q6I3	Salmonella_phage	6.5e-24	78.6

DBSCAN-SWA_3

90266 : 108078

Salmonella_phage(64.29%)

integrase

attL 88547:88564|attR 99742:99759

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
88547:88564	attL	NA	NA	NA	NA
WP_071925344.1\|90266_91079_+	phosphate starvation-inducible protein PhoH	W8D063	Erwinia_phage	4.7e-91	66.1
WP_040170138.1\|91088_91475_+	phage family protein	Q716B1	Shigella_phage	4.9e-46	72.0
WP_032440523.1\|91471_91717_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	9.1e-14	47.4
WP_080031196.1\|91811_92429_+	hypothetical protein	NA	NA	NA	NA
WP_060853801.1\|92438_92849_+	toxin YafO	NA	NA	NA	NA
WP_052455483.1\|92912_93272_-	hypothetical protein	NA	NA	NA	NA
WP_032414134.1\|93626_94727_+\|integrase	site-specific integrase	A0A1P8DTG6	Proteus_phage	9.4e-18	30.0
WP_014342091.1\|94721_95102_-	transcriptional regulator	NA	NA	NA	NA
WP_080031197.1\|95704_97984_+	porphyrin biosynthesis protein	J9Q7G6	Salmonella_phage	4.5e-248	63.1
WP_060611509.1\|98080_99313_+	AAA domain-containing protein	J9Q733	Salmonella_phage	1.6e-212	86.6
WP_080031198.1\|99493_103012_+	DNA polymerase III subunit alpha	J9Q7Z2	Salmonella_phage	0.0e+00	93.0
99742:99759	attR	NA	NA	NA	NA
WP_032414135.1\|103008_103452_+	hypothetical protein	J9Q7S4	Salmonella_phage	2.2e-58	82.3
WP_023279488.1\|103604_103820_-	cold shock protein CspG	A0A1W6JNX5	Morganella_phage	4.5e-25	80.0
WP_023279489.1\|104169_104601_+	hypothetical protein	J9Q6I8	Salmonella_phage	3.1e-65	90.9
WP_040213770.1\|104720_105728_+	hypothetical protein	J9Q7Z3	Salmonella_phage	6.0e-144	88.0
WP_023279491.1\|105788_106733_+	hypothetical protein	J9Q7S6	Salmonella_phage	3.1e-171	93.0
WP_019704549.1\|106732_106999_+	hypothetical protein	J9Q7G8	Salmonella_phage	1.7e-34	84.1
WP_040205269.1\|107001_108078_+	recombinase	J9Q736	Salmonella_phage	8.5e-197	96.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP020065

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1701 : 61253

Escherichia_phage(20.0%)

bacteriocin,transposase,integrase

attL 757:771|attR 30971:30985

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
757:771	attL	NA	NA	NA	NA
WP_020801687.1\|1701_2487_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.9e-52	90.4
WP_020804422.1\|2504_2870_-	hypothetical protein	NA	NA	NA	NA
WP_001568031.1\|3408_4164_+	replication initiation protein RepE	I3WF20	Macacine_betaherpesvirus	2.0e-136	96.0
WP_017901447.1\|5156_5789_+	ParA family protein	A0A0K1LMB9	Rhodobacter_phage	1.8e-29	39.6
WP_017901448.1\|5788_6163_+	hypothetical protein	NA	NA	NA	NA
WP_020801689.1\|6402_7377_+	StbA protein	A0A222YXF2	Escherichia_phage	1.5e-70	44.2
WP_020801683.1\|7380_7773_+	plasmid stability protein	NA	NA	NA	NA
WP_146642489.1\|8130_8358_+	hypothetical protein	NA	NA	NA	NA
WP_026055975.1\|8403_9327_-\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	8.4e-177	99.7
WP_004152641.1\|10786_11218_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_004152640.1\|11214_11943_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_004152639.1\|11939_12266_+	hypothetical protein	NA	NA	NA	NA
WP_004152638.1\|12321_12696_+	hypothetical protein	NA	NA	NA	NA
WP_004220208.1\|12873_13953_-\|transposase	IS481-like element ISKpn28 family transposase	NA	NA	NA	NA
WP_004118124.1\|14024_14186_+	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_004152759.1\|14885_15158_+	hypothetical protein	NA	NA	NA	NA
WP_004152758.1\|15154_15505_+	hypothetical protein	NA	NA	NA	NA
WP_020802743.1\|16140_16497_+	hypothetical protein	A0A248SL90	Klebsiella_phage	5.7e-25	58.1
WP_019706020.1\|16557_16770_+	hypothetical protein	NA	NA	NA	NA
WP_014343499.1\|16780_17005_+	hypothetical protein	NA	NA	NA	NA
WP_004152720.1\|17085_17406_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	6.8e-09	39.5
WP_020801586.1\|17395_17674_+	helix-turn-helix transcriptional regulator	O64356	Escherichia_phage	1.9e-07	39.4
WP_020801587.1\|17674_18076_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_064180866.1\|18904_19726_+	DUF945 domain-containing protein	K4F5L3	Cronobacter_phage	8.8e-45	40.1
WP_001568108.1\|20120_20606_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_015065623.1\|21034_21433_+	relaxosome protein TraM	NA	NA	NA	NA
WP_015065624.1\|21639_22335_+	conjugal transfer transcriptional regulator TraJ	NA	NA	NA	NA
WP_004208838.1\|22418_22790_+	TraY domain-containing protein	NA	NA	NA	NA
WP_004178060.1\|22843_23212_+	type IV conjugative transfer system pilin TraA	NA	NA	NA	NA
WP_004178059.1\|23225_23531_+	type IV conjugative transfer system protein TraL	NA	NA	NA	NA
WP_001339197.1\|23935_25144_+\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0
WP_004153030.1\|25574_26102_+	hypothetical protein	NA	NA	NA	NA
WP_004152629.1\|26291_27023_+	complement resistance protein TraT	NA	NA	NA	NA
WP_004152630.1\|27382_29692_+	type IV conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_004153029.1\|29691_34953_+	conjugative transfer relaxase/helicase TraI	NA	NA	NA	NA
30971:30985	attR	NA	NA	NA	NA
WP_004152303.1\|35032_35758_+	type-F conjugative transfer system pilin acetylase TraX	A0A1D6ZIU7	Xanthomonas_phage	5.5e-06	29.4
WP_004178053.1\|35915_36512_+	fertility inhibition protein FinO	NA	NA	NA	NA
WP_004152301.1\|36531_36879_+	hypothetical protein	NA	NA	NA	NA
WP_004178052.1\|37093_37639_-	hypothetical protein	NA	NA	NA	NA
WP_004178051.1\|37995_40317_+\|bacteriocin	klebicin B-related nuclease bacteriocin	NA	NA	NA	NA
WP_004152296.1\|40318_40597_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_004152294.1\|40865_41417_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	1.1e-19	35.2
WP_004199332.1\|41737_42016_+	replication regulatory protein RepA	NA	NA	NA	NA
WP_004171457.1\|42232_42310_+	RepA leader peptide Tap	NA	NA	NA	NA
WP_004152292.1\|42302_43160_+	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_001339197.1\|43554_44763_+\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0
WP_011977766.1\|45541_45877_-	C2H2-type zinc finger protein	NA	NA	NA	NA
WP_001568067.1\|46049_46331_+	hypothetical protein	NA	NA	NA	NA
WP_000176305.1\|46384_46996_+	DUF2913 family protein	NA	NA	NA	NA
WP_077274559.1\|47309_48461_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	4.1e-173	95.0
WP_000443938.1\|48485_49937_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_009309939.1\|49929_51972_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_009309938.1\|52158_57894_+	DUF4011 domain-containing protein	NA	NA	NA	NA
WP_020802676.1\|58355_61253_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	5.5e-182	37.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP020062

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 70849

Escherichia_phage(35.71%)

transposase,integrase

attL 4006:4034|attR 49643:49671

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152065.1\|1704_2652_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	1.8e-12	30.6
WP_071527918.1\|2678_2990_-	EAL domain-containing protein	NA	NA	NA	NA
WP_004152067.1\|3054_3978_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	2.1e-175	98.4
4006:4034	attL	NA	NA	NA	NA
WP_004197688.1\|4650_4908_-	hypothetical protein	NA	NA	NA	NA
WP_080895248.1\|5527_6964_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004152070.1\|7946_9224_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_004178088.1\|9286_11284_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	9.7e-21	25.9
WP_085955172.1\|12323_13531_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.7e-100	63.2
WP_004178091.1\|14959_15391_-	silver-binding protein SilE	NA	NA	NA	NA
WP_003032875.1\|15641_17117_-	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_001572351.1\|17109_17790_-	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.1e-31	35.6
WP_000475512.1\|17979_19365_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_001246153.1\|19393_19747_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_004152079.1\|19860_21153_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_004098958.1\|21163_24310_+	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	S5VTK5	Leptospira_phage	4.0e-61	22.5
WP_000758228.1\|24396_24837_+	hypothetical protein	NA	NA	NA	NA
WP_004098955.1\|24963_27411_+	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	7.6e-84	35.8
WP_000843497.1\|27451_27649_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_004118669.1\|27682_28420_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4JAF5	uncultured_Caudovirales_phage	1.2e-11	32.5
WP_001067855.1\|31253_31958_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001620097.1\|32810_33899_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_001620096.1\|33985_34246_-	hypothetical protein	A0A077SK33	Escherichia_phage	1.9e-41	100.0
WP_011117369.1\|34543_35404_+	class A extended-spectrum beta-lactamase SHV-5	A0A077SL40	Escherichia_phage	4.4e-156	99.7
WP_002210513.1\|35424_36186_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002210514.1\|36446_37349_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	5.3e-160	100.0
WP_002210515.1\|37360_38626_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	2.7e-234	100.0
WP_002210516.1\|38618_39239_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0
WP_001067855.1\|39950_40655_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_032418008.1\|40730_41231_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000259031.1\|41358_42198_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|42191_42539_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000186237.1\|42695_43328_-	type B-3 chloramphenicol O-acetyltransferase CatB3	A0A2R8FE91	Brazilian_cedratvirus	4.1e-26	41.2
WP_000381802.1\|43410_43944_-	aminoglycoside nucleotidyltransferase ANT(2'')-Ia	NA	NA	NA	NA
WP_000845039.1\|44089_45103_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_048228299.1\|45089_45695_-	hypothetical protein	NA	NA	NA	NA
WP_000019304.1\|45705_46275_-	trimethoprim-resistant dihydrofolate reductase DfrA19	A0A1V0SD48	Indivirus	3.5e-08	27.2
WP_002008781.1\|46274_46775_-	hypothetical protein	A0A1V0SB21	Catovirus	3.3e-10	31.7
WP_004118231.1\|48860_49028_-\|integrase	integrase	NA	NA	NA	NA
WP_004118235.1\|50130_50652_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
49643:49671	attR	NA	NA	NA	NA
WP_004118237.1\|50648_51602_+	fec operon regulator FecR	NA	NA	NA	NA
WP_004152280.1\|51687_54012_+	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_004118241.1\|54056_54959_+	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_004118243.1\|54955_55954_+	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_004152281.1\|55950_56907_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	NA	NA	NA	NA
WP_004152282.1\|56907_57675_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	9.8e-14	25.2
WP_004118251.1\|57773_58067_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.7e-49	96.9
WP_071527925.1\|58397_58640_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000427623.1\|58937_59942_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_004152284.1\|60345_61356_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_004152286.1\|61816_62899_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	6.8e-186	96.4
WP_004152287.1\|63020_66095_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.7
WP_003846917.1\|66146_67400_+	lactose permease	NA	NA	NA	NA
WP_001339197.1\|69640_70849_-\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0

DBSCAN-SWA_2

79322 : 85874

Wolbachia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020802283.1\|79322_79871_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	6.6e-20	30.8
WP_020804816.1\|80055_80646_-	hypothetical protein	NA	NA	NA	NA
WP_080031172.1\|80702_85874_-	conjugative relaxase	A0A1P8DII4	Virus_Rctr197k	2.1e-06	29.6

DBSCAN-SWA_3

108904 : 115205

Hokovirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020802753.1\|108904_110623_+	hybrid sensor histidine kinase/response regulator	A0A1V0SGX0	Hokovirus	5.8e-22	24.5
WP_020802754.1\|110651_110912_-	hypothetical protein	NA	NA	NA	NA
WP_113772542.1\|111549_111936_+	lytic transglycosylase domain-containing protein	A0A0K2QQJ4	Ralstonia_phage	1.9e-05	39.6
WP_032426056.1\|111978_112296_+	hypothetical protein	NA	NA	NA	NA
WP_071599372.1\|112356_112665_-	hypothetical protein	NA	NA	NA	NA
WP_020804822.1\|112724_113546_-	DUF945 domain-containing protein	K4F5L3	Cronobacter_phage	3.0e-45	40.4
WP_042922549.1\|114371_115205_-	N-6 DNA methylase	A0A2K9V411	Faecalibacterium_phage	5.3e-21	34.7

DBSCAN-SWA_4

121092 : 125866

Emiliania_huxleyi_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020802171.1\|121092_123102_-	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	2.7e-26	27.7
WP_004152655.1\|123170_123413_-	DUF905 domain-containing protein	NA	NA	NA	NA
WP_020802172.1\|123460_123973_-	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	8.5e-54	84.7
WP_032425974.1\|124902_125115_-	hypothetical protein	NA	NA	NA	NA
WP_042922559.1\|125302_125866_-	methyltransferase	A0A2I7RHK4	Vibrio_phage	9.7e-19	34.3

DBSCAN-SWA_5

129691 : 151801

Macacine_betaherpesvirus(18.18%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026055975.1\|129691_130615_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	8.4e-177	99.7
WP_004152643.1\|132808_133057_-	DUF905 domain-containing protein	NA	NA	NA	NA
WP_004152644.1\|133105_133648_-	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	6.0e-50	76.7
WP_004152645.1\|134423_134987_-	methyltransferase	A8HNV9	Thalassomonas_phage	1.3e-18	34.1
WP_001339197.1\|135311_136520_-\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0
WP_004198570.1\|137779_138010_-	hypothetical protein	NA	NA	NA	NA
WP_004178072.1\|138101_138329_-	hypothetical protein	NA	NA	NA	NA
WP_004118473.1\|139110_139428_-	hypothetical protein	NA	NA	NA	NA
WP_004152754.1\|139462_139717_-	hypothetical protein	H9C187	Pectobacterium_phage	1.2e-11	50.0
WP_004118478.1\|139953_140379_-	antirestriction protein	NA	NA	NA	NA
WP_004152753.1\|140899_141130_-	hypothetical protein	NA	NA	NA	NA
WP_004152765.1\|141363_142848_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004178083.1\|143253_143679_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.3e-31	49.6
WP_004152715.1\|143678_144950_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	5.6e-155	63.7
WP_004152062.1\|147901_148873_-	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	4.1e-150	86.6
WP_000523813.1\|148872_150039_-	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	1.4e-224	97.7
WP_004152063.1\|150790_151801_+	replication initiation protein	J9Q7H0	Salmonella_phage	8.8e-87	55.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP020064

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

71127 : 82707

Aeromonas_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020314651.1\|71127_71829_-	DNA methylase	A0A2K9VH43	Faecalibacterium_phage	6.2e-23	34.7
WP_020314631.1\|72263_72494_-	hypothetical protein	NA	NA	NA	NA
WP_020314635.1\|72697_72943_+	DinI-like family protein	Q7Y3V9	Yersinia_phage	1.1e-08	39.3
WP_046960466.1\|72939_73389_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.3e-31	52.0
WP_020314652.1\|73400_74675_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	1.3e-148	60.7
WP_020314634.1\|74849_75077_-	hypothetical protein	NA	NA	NA	NA
WP_022644718.1\|75121_75748_-	ParA family protein	A0A2H4EW66	Aeromonas_phage	4.5e-25	34.4
WP_020314642.1\|76345_76966_+	resolvase	A0A219Y912	Aeromonas_phage	1.0e-08	31.0
WP_022644719.1\|76985_77252_+	hypothetical protein	NA	NA	NA	NA
WP_020314639.1\|77372_78326_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	9.5e-75	57.1
WP_020314646.1\|78322_78934_-	DUF2913 family protein	NA	NA	NA	NA
WP_020314648.1\|79251_79530_-	hypothetical protein	NA	NA	NA	NA
WP_000124025.1\|79719_82707_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	2.4e-294	53.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP020061

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020061_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020061_1

1341315-1341415

Orphan

Consensus_repeat	Method
CTTACCGGGCCTACGAACTCGACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020061_1

>merge|NZ_CP020061|1|1341315-1341415|CRISPRCasFinder
CTTACCGGGCCTACGAACTCGACAGGAAGCGGAAGGGCTGCAGGCTATGCAGTTCGAGGCCGCTGCAAGCGCCGCGTCTTACCGGGCCTACGAACTGCGAC

>NZ_CP020061|1|1|1341315-1341415|CRISPRCasFinder
CTTACCGGGCCTACGAACTCGACA	GGAAGCGGAAGGGCTGCAGGCTATGCAGTTCGAGGCCGCTGCAAGCGCCGCGT
CTTACCGGGCCTACGAACTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020061.1\|WP_020802895.1\|1337449_1338412_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270276
NZ_CP020061.1\|WP_009307636.1\|1331139_1331865_+\|polyphenol-oxidase-family-protein	unknown	unknown	gnl\|CDD\|319354
NZ_CP020061.1\|WP_004189524.1\|1335210_1336296_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|238527
NZ_CP020061.1\|WP_020801856.1\|1331877_1333458_-\|rhodanese-like-protein	unknown	unknown	gnl\|CDD\|238793
NZ_CP020061.1\|WP_004143331.1\|1344189_1345011_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_CP020061.1\|WP_002908378.1\|1348045_1348948_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP020061.1\|WP_016532314.1\|1339426_1340422_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223673
NZ_CP020061.1\|WP_020802907.1\|1347095_1348049_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238566
NZ_CP020061.1\|WP_002908439.1\|1340415_1341189_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_CP020061.1\|WP_004148676.1\|1346029_1347082_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP020061.1\|WP_014907422.1\|1334172_1335066_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP020061.1\|WP_002908376.1\|1349040_1349808_+\|basic-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270342
NZ_CP020061.1\|WP_004189530.1\|1338408_1339446_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223787
NZ_CP020061.1\|WP_004143359.1\|1350622_1351345_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP020061.1\|WP_020801854.1\|1333463_1334066_-\|cysteine-dioxygenase-type-I	unknown	unknown	gnl\|CDD\|227840
NZ_CP020061.1\|WP_020802903.1\|1349871_1350636_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP020061.1\|WP_087796173.1\|1336349_1337444_+\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_CP020061.1\|WP_032447905.1\|1351616_1352231_+\|DUF1062-domain-containing-protein	unknown	unknown	gnl\|CDD\|226782
NZ_CP020061.1\|WP_020802901.1\|1341611_1343684_-\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|273805
NZ_CP020061.1\|WP_020802900.1\|1345007_1346033_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223682

Protein	Function_ID	Function_description	E-value
NZ_CP020061.1\|WP_020802895.1\|1337449_1338412_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270276	cd13558, PBP2_SsuA_like_2, Putative substrate binding domain of sulfonate binding protein, the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.24575e-105
NZ_CP020061.1\|WP_009307636.1\|1331139_1331865_+\|polyphenol-oxidase-family-protein	gnl\|CDD\|319354	cd16833, YfiH, protein of unknown function YfiH. This subfamily contains YfiH, a protein of unknown function from Shigella flexneri, E. coli, and many similar proteins which collectively are often called DUF152. The structure of YfiH reveals a distant homology to Rho-activating toxins cytotoxic necrotizing factor 1 (CNF1) as well as chemotaxis protein CheD that stimulates methylation of methyl-accepting chemotaxis proteins (MCPs), all having an invariant Cys-His pair forming a catalytic dyad, and is required by the CNF-1 toxins for deamidation activity.	2.69912e-49
NZ_CP020061.1\|WP_004189524.1\|1335210_1336296_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|238527	cd01094, Alkanesulfonate_monoxygenase, Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin mononucleotide (FMNH2), which is provided by the NADPH-dependent FMN oxidoreductase (SsuE).	5.1831e-92
NZ_CP020061.1\|WP_020801856.1\|1331877_1333458_-\|rhodanese-like-protein	gnl\|CDD\|238793	cd01535, 4RHOD_Repeat_4, Member of the Rhodanese Homology Domain superfamily, repeat 4. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 4th repeat which, in general, contains the putative catalytic Cys residue.	1.63973e-65
NZ_CP020061.1\|WP_004143331.1\|1344189_1345011_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	1.00519e-119
NZ_CP020061.1\|WP_002908378.1\|1348045_1348948_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.19519e-49
NZ_CP020061.1\|WP_016532314.1\|1339426_1340422_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.36619e-38
NZ_CP020061.1\|WP_020802907.1\|1347095_1348049_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	3.60905e-44
NZ_CP020061.1\|WP_002908439.1\|1340415_1341189_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.04308e-109
NZ_CP020061.1\|WP_004148676.1\|1346029_1347082_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.79153e-69
NZ_CP020061.1\|WP_014907422.1\|1334172_1335066_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.46303e-36
NZ_CP020061.1\|WP_002908376.1\|1349040_1349808_+\|basic-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270342	cd13624, PBP2_Arg_Lys_His, Substrate binding domain of the arginine-, lysine-, histidine-binding protein ArtJ; the type 2 periplasmic binding protein fold. This group includes the periplasmic substrate-binding protein ArtJ of the ATP-binding cassette (ABC) transport system from the thermophilic bacterium Geobacillus stearothermophilus, which is specific for arginine, lysine, and histidine. ArtJ belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.97659e-96
NZ_CP020061.1\|WP_004189530.1\|1338408_1339446_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	2.33513e-27
NZ_CP020061.1\|WP_004143359.1\|1350622_1351345_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.91075e-153
NZ_CP020061.1\|WP_020801854.1\|1333463_1334066_-\|cysteine-dioxygenase-type-I	gnl\|CDD\|227840	COG5553, COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only].	9.69554e-53
NZ_CP020061.1\|WP_020802903.1\|1349871_1350636_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.84938e-77
NZ_CP020061.1\|WP_087796173.1\|1336349_1337444_+\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	8.8536e-51
NZ_CP020061.1\|WP_032447905.1\|1351616_1352231_+\|DUF1062-domain-containing-protein	gnl\|CDD\|226782	COG4332, COG4332, Uncharacterized protein conserved in bacteria [Function unknown].	3.03855e-71
NZ_CP020061.1\|WP_020802901.1\|1341611_1343684_-\|TonB-dependent-siderophore-receptor	gnl\|CDD\|273805	TIGR01783, Ferrienterobactin_receptor, TonB-dependent siderophore receptor. This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	2.39318e-100
NZ_CP020061.1\|WP_020802900.1\|1345007_1346033_+\|iron-ABC-transporter-permease	gnl\|CDD\|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	9.1102e-70

>NZ_CP020061.1|WP_002908439.1|1340415_1341189_+|ABC-transporter-ATP-binding-protein
MVTETIARGAAVSISHLHHAFTLGKQTVPVLENISLQLRPGESVALLGPSGCGKSTLLRLLAGLEAPQSGQMQIDGAALGAPGPERILVFQDPTLYPWLTVRQNVLLGPQAQGKKGLEAKADALIDRIGLQAFSEAWPRQLSGGMAQRAALARALLNEPRLLLLDEPLGKLDSLTRISMQRELIALWQQQGYTSLLVTHDIEEALLLCERVLVMSPRPGRIIAEFALPLAFPRHRDNPQLLQHRQDILRILGQEADW
>NZ_CP020061.1|WP_016532314.1|1339426_1340422_+|ABC-transporter-permease-subunit
MPTYSPEQALARPTGRAPLWGEGLLAATLWLLGGLFTLTWPDAGRRWPFSEGWALAQFTLGGGLLLLALSYRYWRARGARVLHAGKWLALLPVLFAVWEGLTAKTAVLPVPFFAPPQALIEVLHDDWPRLLDSLLHSLGLLGLGVLLGTSSGFITGLAIGWSQRIGYWVHPVLRLLGPVPSTALLPLCLFIFPSSFGASVFLIALSTWFPVTVLTWSGVMGIDKAWYDVARTLGASQRFLILRVAIPAALPNVFVGLFMGLGASFSVLIVAEMVGVKSGIGFYLQWAQGWAAYPNMYAALLVMALLCSGLISGLFMLRDRLLSWQRGGMQW
>NZ_CP020061.1|WP_004189530.1|1338408_1339446_+|ABC-transporter-substrate-binding-protein
MTRTPFSRRRFLQLSGGLALAGVSLPLWAHDMADMAGGDAHPALRLPEPYKIKLAINKSAVCLAPVAVAEQQKIFSKYNLDVEFVNFGSSTDVLLEAIATGKADAGVGMALRWLKALEQGFDVKLTAGTHGGCLNLLTAKDSPFGGLESLKGQTIGVTDMAGPDKNFFAILLKRHGIDPISDVQWKVYPADLLSVALDKREIAAISGSEPFSYRLLETGKYQLIASNMTGDYANLSCCVLGVSGSLARDHKPAAAALTQAILEAHSYAAAHPESVAQSFLAHALNTSEAEVSGILHGQGHGHHAVGEAFVKELTQYAVDLQRVQVIKPGTDPHQFAESIYANVFA
>NZ_CP020061.1|WP_020802895.1|1337449_1338412_+|ABC-transporter-substrate-binding-protein
MRLSFSGRLAAALMLLALGGYATAQERLTLRIADQKGGMRSQLEAANALQNLPYDIKWAEFPAAAPLAEALNAGAVDAGIIGDAPLLFALANGAPVKAIAVDKSNPAGTAVLVSPGSTLKSGADLKGKRIATGKGSIGHFVALKALEQAGISPKEVQWVFLGPVDAKVALLNGSVDAWATWEPYTTQMVKTNEGQILVSGKGLLPGNTFLAATDPALNDPQKRAALQDYLQRLAGAERWAYANLDSYGKTLGEIIRFPAEIARAQFANRQSQWQPLAEETVAQQQATADFYLANGLIRTRLDVKPTFDRRFSVPAAEVTP
>NZ_CP020061.1|WP_087796173.1|1336349_1337444_+|acyl-CoA/acyl-ACP-dehydrogenase
MAEQAASLDASGEFPWRNIDHLRAGGWLSLAVPPSCGGAGASLAQLQQVIAAIAWGEPATALIVCMQYLHHLRLAENDAWHAPLRQQVFHDAVEHGGLINSLRVEPELGSPARGGLPDTVATRRAEGWDISGHKIYTTGIEGLRWLAVWARSDDNPPLVGTWLVPGDSPGITVVKSWDHAGMRATGSHEVIFNHVRVAAEHAVDVWPTDAPPAAQAEPFRLFANRQTALLAAIYDSIAHAAHDWLVRWLAGRVPAGLGHPLSRLPRVQEKVGQIAGLLLVNRSLLEQAAALRFSAIEANLAKVTITDNAIQAVNIALELTGNHGLSRQNPLERHYRNVLCGRVHTPQSDSAWLAAGNFVFQSQG
>NZ_CP020061.1|WP_004189524.1|1335210_1336296_+|LLM-class-flavin-dependent-oxidoreductase
MSIQFLGMIGHRLSSETIAPVGPIFDRDYIVRFAQTHEAAGFDRLLVGHWSDQPDGFLVTALAGLSTQKIQYLLAHRPGFVSPTLAARKFATLEHLLGGRLAVHIISGGNDAEQRRDGDYLDHDQRYARTDAFLDTVRQVWTSEQPVDIHNDFYQAEQAWSAIRPLQKPHLPIYFGGSSEAAIAVAGKHADVFALWGESLAQTGETIQRVRAEAAKHQRDIGFSVSFRPIIADSEAEAWEKAEHILHVATEQAAQRGGGFKAKPESIGAQRLRATAAQGRVVDKRLWTGIAQLVGGGHNSTALVGTPEQVADALLDYYDLGVRNFLIRGFDPLNDAADYGRALLPIAREKAARRAVAERAS
>NZ_CP020061.1|WP_014907422.1|1334172_1335066_+|LysR-family-transcriptional-regulator
MRIDDIDALLATVQFSSLNQAAEYLGITQSAITRRLQRLEQELNVTLLERQTRPLTLTAAGHRVYEQCLSIKRETKKLYSLLDPEGEPRGALRLGVPQSLSEIALPAALSALSQQFPGLSPQITCGWSGQLQRRLENGELDGMLAMGPAQQSFAEGYSGRLLCPLEVVPIVGRRLNLRASSLRECAERGWILNPDGCGLRAGLIRELQSQGLRLTLNVESAGAQLQIALVAQGLGLGLVPRAALASSPWRDEVAVLSLSDFQPAVSLWLIHAQYLANLQPPLTFFASKVVQQLTVSD
>NZ_CP020061.1|WP_020801854.1|1333463_1334066_-|cysteine-dioxygenase-type-I
MTAPRLEKLRHFIHEVDRLHREHHQTAPLLDAVAQRLAALVRYDDWLPEEYTLPHPHHYQQYLLHADSGERFSIVSFVWGPGQATPIHDHRVWGAIGMLRGAEENQRYQLDADGIPRALGAATLLEAGQVEKVSADDGDIHRVSNALADRVSISIHVYGGNIGVVKRAVYTPEGQQKPFISGYSNRHLPNIWDSSREHQG
>NZ_CP020061.1|WP_020801856.1|1331877_1333458_-|rhodanese-like-protein
MSTYAYRQAAGIRQALLDRRELALIDVREEADFATAHPLFAVNLPLSKLELEVRRRIPRFTTPLTVYDNGEGLAEIAVERLRSWGYQDVALLAEGLAGWRRSGGELFQDVNSASKAFGELVESVHHTPSLSAQEVQALIDSRQEVVIVDARRFDEYQTMSIPGSISVPGGELALRVESLTPSPQTPVIVNCAGRTRSIIGTQSLINAGVPNPVHALRNGTIGWTLAGQTLAHQQQRQYDPSARASGARAAEVAHFAERAGVAVIDEATLQRWLQQSDRTTFLFDVRSPEEYAAGHYPGSLSAPGGQLVQETDHFASVRGARIVLLDDDGIRAAITGSWLAQMGWETARLSALSTSQLSERGVPAAEVPPGPQAEEISPTQLAQQLEEPGTVVLDFTTSANFVARHIPGAWWLTRSQLRQALEAIPPAQRYVVTCGSSLLARYAVPEVAALTGKPVQLLTGGTLAWIAAGLPLAHGDSGLAVERRDRYRRPYEGTDNSAEAMQAYLEWEYGLVDQLARDGTHGFRVL
>NZ_CP020061.1|WP_009307636.1|1331139_1331865_+|polyphenol-oxidase-family-protein
MAYTSRLLNAIPGIRHAFLDVHETAAFPYAELAPVKLVHGNEVHHYQQPLPTRPHADAVFTAVAGQKVGVVTADCLPLLIASRDGRYVCSVHAGWQGLVSGIVDNSLACFRQQGVALADLVIAVGPYIHPCCYEVSAGFYQQLLDQPGGDRVARHRQRLFHSRSGPVSDPLKAAARGSDNLWFDLRAFAEAIFAEAGVAPASVEWLGSCTYCTPQSLGSYRRRTHFPAPKSFQYSWIMREA
>NZ_CP020061.1|WP_020802901.1|1341611_1343684_-|TonB-dependent-siderophore-receptor
MAADNRAAKSTNDAEETITVVADGAQQSATSGYQPLSSATATLTSMPLLDIPQVVNTVSDRVLEDQHATSLDEALYNVANVVQTNTLGGTQDAFTRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTLYGILDPGGLINVITKRPERQFSGSVSGTSTSFGGGTGSVDITGPIEGTNLAYRLIGEYQNEDYWRNFGKNKSSFIAPSLTWFGERATVTASYSHRDYSAPFDRGTIFDLNTGHAVNVDRKTRFDEAFNITDGYSDLAQLNAEYRLNDAWTARFDYSYSQDHYNDNQARVMAYDSATGNLTRRVDGTHGSTQKMHSTRADLQGNVVVGGFYNELLTGVAYENYDLLRTDMLRCKNVKGFNIYHPVYGTLDTCNTVSASDSDQRIQQESYAAYVQDALYLTDNWIAVAGVRYQYYTQYAGKGRPFNVNTDSRDEKWTPKAGLVYKITPNVSLFANVAQSFMPQSSIASYIGELPPEESTSYEVGAKFDLLNGITANIALFDIHKRNVLYTESIGDETVAKTAGKVRSQGVEVDLAGSITDNLSVIASYGYTDAKVLEDPDYAGKALPNVPKHTGSLFLTYDIHNVYNSNTLTVGGGGHAVSKRSGTNGADYYLQGYAVADVFAAYKMKLQYPVTLQVNVKNLFDKTYYTSSIGTNNLGNQIGDPREVQFTVKMDF
>NZ_CP020061.1|WP_004143331.1|1344189_1345011_+|ABC-transporter-ATP-binding-protein
MPQRVKPAEQGIVLDALSAGYGQTLIVDDINLTIPTGKMTVLAGANGSGKSTLLSTIARMLKPLGGCVRLDGQAIHQMPTKTVSRQLGILPQSPLTPEGLTVFELVSRGRYPWQGLMRQWSEADELAVEEALRLTGTAEFAHLPVDSLSGGQRQRCWIAMALAQQTATILLDEPTTWLDLRYQVDILELLQTLTREHGRTVVTVLHDLNFAVNYADLLVFLKQGRIAGTISDNDVCSPELIKRVFDVDVQMSINPQTGKPFFMPFRARQAAAQ
>NZ_CP020061.1|WP_020802900.1|1345007_1346033_+|iron-ABC-transporter-permease
MSVAILLSARRRPRPRLALLLLTLLLIAASLVHLGLGARWIAPQTVLQALLEYDPRNFEQRIIIDLRLVRLAAALLTGAALGVAGLLLQTVIRNPLGEPHILGLNAGASLAVVATSALGLSFGAFPAGRPLTAACGAGLLFGGVMALASAGSGGATPLRITLCGVALSGFASAVTAAILILDEQTLLAMRTWLAGDLAGLNWSTLQTALVPALIGLGVALLIAPRLNVLALGDKVALGLGVNLVQTRLLGLLAIALLCGAAVAVAGPIGFVGLVVPHVVRRLVTEDIRLALPLAAPVGALVLVLADIAARTLVAPQELATGAMTALVGAPLFIFIAARFFK
>NZ_CP020061.1|WP_004148676.1|1346029_1347082_+|iron-ABC-transporter-permease
MTRAVHRAGFRPLAFASRQLLLRPAALKIAASIVLTLLALGLYSLSRGSYPLPASTLARALLAPQEMGEQPRFILFDIRLPRILMALLCGAMLGLAGAAMQSITRNGLADPGLIGVKEGASIVVLALVLFFPAVGLVWRPLAGMVGGIAVALLVLTLARDCSRPRFILIGIGVSWSLAAAVGIFMTTADVRDVQTAMIWLAGSLQAATWPLLAVAFCWALPGAIILFCTARAADVALLGDRTAIGLGVRLQQLTVLRFFAPVLLTSASVSCVGSLGFVGLMAPHMARFVLRGGQVSLLCGSALIGALLVLATDTLGRLAFAPLQIPAGIVIALVGCPFFVVLLWRRRDAL
>NZ_CP020061.1|WP_020802907.1|1347095_1348049_+|ABC-transporter-substrate-binding-protein
MRWFVSLLLLLTGAVSAAAPQTQTFTDDLGRTVTVPLHPQRIVSMHDLDITIPLIELGAPPIASHGRTRPDGSHYLRSSAQLTGVDFDNSDIRFIGTADIDLEAVAAARPDLIITEPSRHVSVEQLEKIAPTVSIDHLQGSAPEIYRKLAQLTGTQPRLAILERRYQEQIKQLKAMVNPPQYSVSVIQANNGKVTVHHSYHALGRVLRDAGFRFPPLIERIPDGQRIDVSAEQLPELDADFVFATWRSDTGGKPQDELQAMEGVMPGWCDFLRACRTGHYILLPREEVISNSYAALSLMVAQVQSHIAGRPIPAEAK
>NZ_CP020061.1|WP_002908378.1|1348045_1348948_+|MurR/RpiR-family-transcriptional-regulator
MKSAVKKEKGKVDLFGERYRARAHQLSPRLRAVVSYINDNREVVLEHTAMEIATATQTSDATVVRAIQALGFAGLRELKQTMERWFGTSVTSAEKMRSTVTALSSDVNSSIDFVLEGHQRVCEVLSRADNRAAVAQAVALLSDARQVGIFGIGASGILAEYTARLFSRIGLPAYVMNRTGFSLAEQLIGLQRGDVLIMMGQKSPHREGLTTLREAKRLGIPTILLTQAVDSRFSQEAQVVIDVPRGGDSSRMPLHGTVLVCLEMIVLSVASTTPQKTVKSLKRINDLHRAIGKSGGKRGH
>NZ_CP020061.1|WP_002908376.1|1349040_1349808_+|basic-amino-acid-ABC-transporter-substrate-binding-protein
MVKNLLKACCMIAALTAAGQAAAETYTVGSGGTYRPFEFENSQKQLEGFDIDIIKAIAKAEGFDVKLVNTPWEGIFATLNTGDRDIIISGITITDKRKQMVDFSAPYFPAEQSIVVAQDSQVDSLAALKNEKVGVVNSSTGDIVVSEVLGKNSTAIKRFDNTPLMLQELFEDGVSAAVGDVGVVKYYIKQHPEKQFKLVPDAKFERQYFGIAVAKGNSELLGKINAGLQKIVADGTYAKIYKTWFDDNVPTLPAQ
>NZ_CP020061.1|WP_020802903.1|1349871_1350636_+|amino-acid-ABC-transporter-permease
MTGFRWEIIEEYGPLFVDGALMTIKCTIICVILGTLWGLTLGLGRMAKAEHGPWKYILRYLVQFPVRFYVSAFRGTPLFVQIMVVHFALVPLFINPRDGLLVTSGLMSADFARELRASYGAFLSCIVAITLNAGAYVSEIFRAGIQSIDKGQMEASRALGLPWWKTMRKVILPQAFRRILPPLGNNAIAIVKDSSLASAIGLADLAYAARTVSGAYATYWEPYLTISLVYWVITFLLAQLVNRLEKRFGKSDSH
>NZ_CP020061.1|WP_004143359.1|1350622_1351345_+|amino-acid-ABC-transporter-ATP-binding-protein
MIHINNLHKRFGDSHVLRGISCDIKPQEVVCIIGPSGSGKSTFLRCMNALETVSEGEVVVNGFAAHDRTTDLNKMRESVGMVFQRFNLFPHMTVLENLIMAPMNLRNMPRQQAIDLAEALLAKVGLSDKRDAWPSSLSGGQQQRVAIARALAMKPSIMLFDEPTSALDPELVGDVLEVMKNLASEGMTMVIVTHEMGFAREVADRVIFIDQGVIQEEGKPGQIFSAPTNPRTAAFLSKVL
>NZ_CP020061.1|WP_032447905.1|1351616_1352231_+|DUF1062-domain-containing-protein
MTVTWTVTPVGYQHIAKRCPACNVKRDFAPSGAIRVNSQKKLLDIWSIYKCTRCDYTWNIALFSRQHVSKINRELLQRLLQNDAAMVHYYAADLATLKRNRAEPSGQPDFRIHEQWSVTLMACQRITVRVRVSQPFRISLLSILKKQLKLSTAEIRWLVATGHIEGIPLKQLKTKKLKAMEYDFQLAAETLYARRRITLSLCGR

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Crispr_ID: NZ_CP020061_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020061_2

1365857-1366250

TypeI-E

I-E,II-B

Consensus_repeat	Method
GTCTTCCCCACATGCGTGGGGGTGTTTC	PILER-CR
GTCTTCCCCACATGCGTGGGGGTGTTTC	CRISPRCasFinder
GTCTTCCCCACATGCGTGGGGGTGTTTC	CRT

6 spacers

cas3,cas8e,cse2gr11,cas6e,cas7,cas5,cas1,cas2

The CRISPR arrays of NZ_CP020061_2

>merge|NZ_CP020061|2|1365857-1366250|PILER-CR,CRISPRCasFinder,CRT
GTCTTCCCCACATGCGTGGGGGTGTTTCCGAGCTCATCGCCTCCCTGGAGACGGCGGGCGAGTCTTCCCCACATGCGTGGGGGTGTTTCTATAGTATGACGATTGATTCCACTCATCAATTTGTCTTCCCCACATGCGTGGGGGTGTTTCCAAGACACCTGCAAACGGTATATCTTTGGAGTGGTCTTCCCCACATGCGTGGGGGTGTTTCCTGTTTCATTCGCTCCGATGGCTCGATCTCCGCGTCTTCCCCACATGCGTGGGGGTGTTTCTTTTCGAACGTCATCGACGGCTTTTAGCATTTAGTCTTCCCCACATGCGTGAGGGTGTTTCCATTGGCTGTGGCGCTTGGACAATCGGCAAAGGGCCTTCTCCACATGCGTGGGAGTGTTTT

>NZ_CP020061|2|1|1365857-1366189|PILER-CR
GTCTTCCCCACATGCGTGGGGGTGTTTC	CGAGCTCATCGCCTCCCTGGAGACGGCGGGCGA
GTCTTCCCCACATGCGTGGGGGTGTTTC	TATAGTATGACGATTGATTCCACTCATCAATTT
GTCTTCCCCACATGCGTGGGGGTGTTTC	CAAGACACCTGCAAACGGTATATCTTTGGAGTG
GTCTTCCCCACATGCGTGGGGGTGTTTC	CTGTTTCATTCGCTCCGATGGCTCGATCTCCGC
GTCTTCCCCACATGCGTGGGGGTGTTTC	TTTTCGAACGTCATCGACGGCTTTTAGCATTTA
GTCTTCCCCACATGCGTGAGGGTGTTTC

>NZ_CP020061|2|2|1365857-1366250|CRISPRCasFinder
GTCTTCCCCACATGCGTGGGGGTGTTTC	CGAGCTCATCGCCTCCCTGGAGACGGCGGGCGA
GTCTTCCCCACATGCGTGGGGGTGTTTC	TATAGTATGACGATTGATTCCACTCATCAATTT
GTCTTCCCCACATGCGTGGGGGTGTTTC	CAAGACACCTGCAAACGGTATATCTTTGGAGTG
GTCTTCCCCACATGCGTGGGGGTGTTTC	CTGTTTCATTCGCTCCGATGGCTCGATCTCCGC
GTCTTCCCCACATGCGTGGGGGTGTTTC	TTTTCGAACGTCATCGACGGCTTTTAGCATTTA
GTCTTCCCCACATGCGTGAGGGTGTTTC	CATTGGCTGTGGCGCTTGGACAATCGGCAAAGG
GCCTTCTCCACATGCGTGGGAGTGTTTT

>NZ_CP020061|2|1|1365857-1366250|CRT
GTCTTCCCCACATGCGTGGGGGTGTTTC	CGAGCTCATCGCCTCCCTGGAGACGGCGGGCGA
GTCTTCCCCACATGCGTGGGGGTGTTTC	TATAGTATGACGATTGATTCCACTCATCAATTT
GTCTTCCCCACATGCGTGGGGGTGTTTC	CAAGACACCTGCAAACGGTATATCTTTGGAGTG
GTCTTCCCCACATGCGTGGGGGTGTTTC	CTGTTTCATTCGCTCCGATGGCTCGATCTCCGC
GTCTTCCCCACATGCGTGGGGGTGTTTC	TTTTCGAACGTCATCGACGGCTTTTAGCATTTA
GTCTTCCCCACATGCGTGAGGGTGTTTC	CATTGGCTGTGGCGCTTGGACAATCGGCAAAGG
GCCTTCTCCACATGCGTGGGAGTGTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020061.1\|WP_020802899.1\|1375699_1376815_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020061.1\|WP_004180288.1\|1374668_1374956_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|187779
NZ_CP020061.1\|WP_020802908.1\|1373815_1374691_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP020061.1\|WP_004184361.1\|1354586_1355021_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NZ_CP020061.1\|WP_020802905.1\|1376825_1377509_+\|DUF4926-domain-containing-protein	unknown	unknown	gnl\|CDD\|379816
NZ_CP020061.1\|WP_004180297.1\|1370816_1371383_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP020061.1\|WP_020802890.1\|1352359_1352752_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NZ_CP020061.1\|WP_020802894.1\|1366662_1369278_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP020061.1\|WP_002908294.1\|1362772_1364542_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
NZ_CP020061.1\|WP_019705845.1\|1356631_1357789_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|349916
NZ_CP020061.1\|WP_004148647.1\|1360228_1361308_-\|malate/lactate/ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|182240
NZ_CP020061.1\|WP_004180292.1\|1373099_1373816_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|273842
NZ_CP020061.1\|WP_004891293.1\|1371375_1372023_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|187858
NZ_CP020061.1\|WP_015958569.1\|1357831_1359982_-\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|130652
NZ_CP020061.1\|WP_020802906.1\|1369281_1370805_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
NZ_CP020061.1\|WP_020802897.1\|1361610_1362699_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224753
NZ_CP020061.1\|WP_020802904.1\|1352788_1354021_-\|multidrug-efflux-MFS-transporter-MdtM	unknown	unknown	gnl\|CDD\|237958
NZ_CP020061.1\|WP_004148650.1\|1355137_1356337_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341030
NZ_CP020061.1\|WP_004184356.1\|1364534_1365605_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP020061.1\|WP_020802896.1\|1372052_1373087_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153

Protein	Function_ID	Function_description	E-value
NZ_CP020061.1\|WP_004180288.1\|1374668_1374956_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187779	cd09648, Cas2_I-E, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	6.96252e-30
NZ_CP020061.1\|WP_020802908.1\|1373815_1374691_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.04474e-119
NZ_CP020061.1\|WP_004184361.1\|1354586_1355021_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.06743e-36
NZ_CP020061.1\|WP_020802905.1\|1376825_1377509_+\|DUF4926-domain-containing-protein	gnl\|CDD\|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	4.69453e-18
NZ_CP020061.1\|WP_004180297.1\|1370816_1371383_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.02768e-28
NZ_CP020061.1\|WP_020802890.1\|1352359_1352752_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.84949e-41
NZ_CP020061.1\|WP_020802894.1\|1366662_1369278_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	5.5709e-73
NZ_CP020061.1\|WP_002908294.1\|1362772_1364542_+\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	6.24955e-103
NZ_CP020061.1\|WP_019705845.1\|1356631_1357789_+\|amidohydrolase	gnl\|CDD\|349916	cd05666, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases or hippurate hydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0
NZ_CP020061.1\|WP_004148647.1\|1360228_1361308_-\|malate/lactate/ureidoglycolate-dehydrogenase	gnl\|CDD\|182240	PRK10098, PRK10098, putative dehydrogenase; Provisional.	0
NZ_CP020061.1\|WP_004180292.1\|1373099_1373816_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	5.1815e-54
NZ_CP020061.1\|WP_004891293.1\|1371375_1372023_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	2.68693e-52
NZ_CP020061.1\|WP_015958569.1\|1357831_1359982_-\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|130652	TIGR01591, Formate_dehydrogenase_subunit_alpha, formate dehydrogenase, alpha subunit, archaeal-type. This model describes a subset of formate dehydrogenase alpha chains found mainly archaea but also in alpha and gamma proteobacteria and a small number of gram positive bacteria. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The enzyme's purpose is to allow growth on formate in some circumstances and, in the case of FdhH in gamma proteobacteria, to pass electrons to hydrogenase (by which process acid is neutralized). This model is well-defined, with only a single fragmentary sequence falling between trusted and noise. The alpha subunit of a version of nitrate reductase is closely related.	0
NZ_CP020061.1\|WP_020802906.1\|1369281_1370805_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	1.27688e-74
NZ_CP020061.1\|WP_020802897.1\|1361610_1362699_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|224753	COG1840, AfuA, ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism].	1.29053e-47
NZ_CP020061.1\|WP_020802904.1\|1352788_1354021_-\|multidrug-efflux-MFS-transporter-MdtM	gnl\|CDD\|237958	PRK15403, PRK15403, multidrug efflux MFS transporter MdtM.	0
NZ_CP020061.1\|WP_004148650.1\|1355137_1356337_-\|MFS-transporter	gnl\|CDD\|341030	cd17477, MFS_YcaD_like, YcaD and similar transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MFS-type transporter YcaD, Bacillus subtilis MFS-type transporter YfkF, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.83425e-59
NZ_CP020061.1\|WP_004184356.1\|1364534_1365605_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	2.11253e-144
NZ_CP020061.1\|WP_020802896.1\|1372052_1373087_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.15885e-110

>NZ_CP020061.1|WP_004184356.1|1364534_1365605_+|ABC-transporter-ATP-binding-protein
MIELSVENLHLTYGDNPVLKGVSMTLGRGEVVSLLGPSGSGKTTLLRAVAGLEKPTSGRIAIGNRTVYDGTPRSEIPAEERNLGLVFQSYALWPHKTVFDNVAYPLKLRKVAAGEIKERVQRVLDQLGLGHLGNRHPHQLSGGQQQRVAIGRALVYNPPVILLDEPLSNLDAKLREEARVFLRELIIKLGLSALMVTHDQNEAMAISDRILLLNNGVIEQQGTPQEMYGSPATLFAAEFMGSNNRLHGKVMALENGRARIEGASWSLWGRAGEGVSVGEPATAVIRVERLRLDGAAQDNSLQLPLLTSMYLGDRWEYLFRTEGDDFPLRAYGTALRDAEHCHLTLPAEDVWIFPQQ
>NZ_CP020061.1|WP_002908294.1|1362772_1364542_+|iron-ABC-transporter-permease
MNVLRRKWQGLPRGVVVCITALVIYVPLLFIVVQSFLSAPFFSRSKSWSLEAFAFIFTDPDFYLALRSGFILAFGLVIIAIPLGGILAFLMVRTDLPGRRIIEPLILVPIFVSPMVLGFGYVVAAGPVGFFSQWAQQLIGFVPWNIYSMFSIVVIAGLTHVPHAYLYISSALRSVGSDVEEAARTVGATPLQVMTSVSLPMVRPSILYACVLLFFLGLEVFGLMLVLGDPEGNMVLATYLYKLTNKLGTPSYHLMAAVAVVLICITIPLVMLQRRLMRTANRFVTMKGKASQARALPLGKWRWVAGAVVVAWLTVTIGVPLLGVALRAFISNWGVGVSLWDELSLATFHNIWQQPNLLRAIVNSMAIGIIGGALAVICYLFVGIAMHRKADNVTRFLDYSVLVPRAVPGLLAGLAFLWVFLFVPMWLDQSLKHGWLSALPVADWLREHLIVQLRALRNTIFSVWLAYTVVWMAYGLRLISSTLLQVGPELEEAARSTGASRGQITRHVTVPLSRYGLIGSWLLMFLIFEREYSTGVYLLSPGTETIGSMLVSLWAAGAIDIVAALSFINILLVVIGLGIALRFGVKLHD
>NZ_CP020061.1|WP_020802897.1|1361610_1362699_+|ABC-transporter-substrate-binding-protein
MYKKISGLVVSLTAVFACAAWAEVPAGYPADYQKTIDAAVKEGKVVIYSTTDTKAAGPLIKGFEAQYPGVKVEYNDMNSTELYNRYISEQAAGGGSGDVVWSSSMDTALKLATEYAEQYASPEVKQLPDWAVWQQKAYGTTYEPVVFIYNKRLIPQNEVPDSHTALAKLIASQADKFKGKVTTYDIEKSGLGFMLAVQDSQADANYFADLANIAKGGLTVQSSTGTMMERVSSGENLIGYNILGSYAEARAKNDPSLGIAYPKDYVLVLSRVSFISQESEHPNAARLWLDYVLSEKGQQILASQADIPSIRRDIAGKNDIDGMTALLGKALKPIPVNETLLDYLQPQKRLQFIKQWRSAAAK
>NZ_CP020061.1|WP_004148647.1|1360228_1361308_-|malate/lactate/ureidoglycolate-dehydrogenase
MPTGHRFLATDLHQFVVSLFTHLGSTPGEATLVADHLIAANLAGHDSHGVGMIPSYVKSHAGGFLQLNRHATVTKDAGAVVTLDGNAGFGQVVAHEAMQLGIEKAKQHGMAAIALRNAHHVGRIGYWAEQCAAAGLISIHFVSVIGDPMVAPFRGKDSRFGTNPLCVVFPRAGHPPLLLDYATSAIAFGKTRVAWHKGEAVAPGCLIDAEGRPTTDPAVMQTSPLGALLTFAQHKGYALATLCEVLGGALSGGQTTHQESLQTSVDAIFNCMTTVILRPDAFDAPDSQAQTEAFIAWCKQSPHDADAPVLAPGEWEAANREARLAQGIPLDAGSWQAICAAARDVGLSESHFDRCRPLA
>NZ_CP020061.1|WP_015958569.1|1357831_1359982_-|formate-dehydrogenase-subunit-alpha
MKKITSVCPYCGAGCKLKLVVDNNKIIRAEAADGVTNQNQLCLKGYYGWDFLNDTQLLTPRLKQPMIRYQKGGAFTPVSWQEAIRYTASKLREIKEKHGPRAIMTTGSSRGTGNETNYVMQKFARAVLNTNNVDCCARVCHGPSVAGLQQALGNGAMSNSISDIENSKCLLVFGYNCADSHPIVARRVIKARDNGAKIIVCDPRRIETARIADRHLQLNNGSNMALVNAFGYVLLEEELYNKTYVERYTEGLDAYREAVKDYAPEAVEGIVGVSAREIREAMRMFAAAPSATIMWGMGVTQFGQAVDVVRGLASLALLTGNLGRPNVGVGPVRGQNNVQGACDMGVLPNLFPGYQEVTDPAVRAKFAAAWGIDPALMDDQVGTRITEVPHKALTGEIKAYYIMGEDPLQTEADLGLVRKGIEALDFVVVQDIFMTKTAEMADVLLPATSWGEHGGVFTCADRGFQRFEQAIPPAGNVKRDWEIISLLASELGYPMHYENNQQIWDEMRELCPLFYGVTWEKMGDMGHVQWPCPTLDHPGTPWLYKDNRFDTPSGKGQLFATAWRAPAERPDDEWPLVLCTVREVGHYSCRSMTGNCAALQSLADEPGRVQMNPADAQRLGIADKQLVWISSRRGKVISRADLSDRINPGAVYMTYQWWVGACNELTQDNLDPISKTPETKYCAVKVEAIADQQWAERYAWTAYSDMKARLKAAADV
>NZ_CP020061.1|WP_019705845.1|1356631_1357789_+|amidohydrolase
MAVSPSLIAEAVGWRREFHAAPELGYQEQETSRRVAELLASFGLQVHRGLAGTGVVATLENGPGPVIGLRADMDALPITELGSVSYRSRRPGVMHACGHDGHTAMLLAAAAHLAQTRHFSGTVHFVFQPAEENLGGARKMVEEGLFERFPMDAIYALHNWPGIPLGEVALSDGAMMASLDAFEITLRGKSCHAAMPESGADPIVAAAQLIMALQTIPSRRLSPQDSAVVSITQINGGEAINVLPDTVVLRGTFRCLSNRVRARVRELIESYVATQPQVSDVQGEISWFPGYPVTKNHALQAQQVREVAVATLGAQAVRWNQAPSMASEDFACMLEACPGAYFWIGTDGETPSKPLHNASYDFNDALIGPGVAMWVGLVEKQLPAA
>NZ_CP020061.1|WP_004148650.1|1355137_1356337_-|MFS-transporter
MFNPDQNRLAPTLAMIMAASLVGFITGYTVPLISLELAQQQIAPLYVGLLAALPPAGMMISSFLSPALCRRVEMGVLLSGSLILLALATIASCMTTDMTLLLLPRLLTGLASGVIIVLGESWITGGAAGSQRATLTGLYASAFTGCQLAGPLLISVGPAWQTSALIAIVAVTAVCLLMLRHLPTGTRESLGERASWRSLGAFLPVLASGVFCFAFFDASILALLPLYGMDKGLNEGLAVLLVTVVLTGDAMFQTPLGWLADRVGIRRVHLSCAVVFSLSLLALPLMLGSRIQLMAICLLLGAAAGALYTLSLVRAGKTFNGQKLIMINALFGFFWSAGSVAGPVVSGMLIGITGYDGLIVTLVASGVLFLLIQCLCKNEKTLLASEQEDDMDEATESAR
>NZ_CP020061.1|WP_004184361.1|1354586_1355021_-|VOC-family-protein
MESNTLHRGRLIDHILLVVEDFEASKNFYTAVLSALEIPVITTANEYLLADELVVASRRSPEAAGKLTGRHHLAFQARDRDMVDAFYHAALTHGGRDNGAPGERHYHPGYYAAFVLDPQGNNIEAVYHGKAERSAGSVAISFTQ
>NZ_CP020061.1|WP_020802904.1|1352788_1354021_-|multidrug-efflux-MFS-transporter-MdtM
MKLALGPYIRFSRILLFPLAMVIYDFSAYLTTDLIQPGIIHIIREFEADVALAPASVSLYLAGGLALQWLLGPLSDRIGRRPVLLTGAIIFALACFSMIFVTSIDQYLIARFIQGTSICFISTVGYVSIQEAFDEKESIRIMAALTSIVLLAPVIGPLAGAGLMNFLHWKLLFAIIGAMSLLAWALLIFNMPETVTSQGRGFRPGEVFSEFVRAFKQPVVLTGALALSFSNLPIITWVALSPVILIDDGGMSRGAYAWTQVPVFGGVIIASIIVARFIKDPTSPRFIWRTIPIQLTGLLVLLAGNIAWPHTWWWSVSGTSLYALGTGLLFPVLFRFALFSHSLPKGTVSATINIVALSFMAASVEVARWVYFQAGGRIAFHCLALIAGIVVIMLVSRLLKLRQQHLLQPT
>NZ_CP020061.1|WP_020802890.1|1352359_1352752_-|VOC-family-protein
MFSYIMLGTNDLPRAIKFYDPLMALLGHVKAGRNEQGASWGTFNGNHTCGLCVGVPFDQQPAGVGNGTMVALNARSVAHIAELHALALQLGGRDEGGPGHRPQYGDGFHSAYVRDPDGNKLAFVYYTSTD
>NZ_CP020061.1|WP_020802894.1|1366662_1369278_+|CRISPR-associated-helicase-Cas3'
MRRLIRVSLQNQHAIAAISFENCPAKTRMLSDGRVVQGRSVLSHCQIVGEIARALIALYPEPMRSRLFPAGSEMAAAGHDIGKVSPTFAAKIFAACDVNDHRLAGLSAVNPGLETLWGGHAGVSQATAESLHAPRYVPEILGQHHGFNPGLNGRRGDAEVFGGPLWFDERKKLVDKLKAEFSADWPTFDSAAQARVVAGLTSVADWIGSGEFFENPEQAWQPVITAALNNAGFIKPVIRQGLSFADVFFPDDPSKKPREAQSRFIDQVVGPGLYILEAKMGMGKTEAALYAAYQMLLQEKATGIYFALPTQLTSNKIYDRFNAFLHQIVSTETPQHALLLHSGAWLMDTEMGEEGSPGGAWFNHRKRGLLAPFAVGTIDQALMAVMNVKHGFVRAYGLAGKVVILDEVHTYDLYTGTILNALVEFLRQIDCTVIILSATLSQTRRDALLQQSTTSEAYPLITAAPSAERERGLVEISVPVTENTTVILHSCRKDESAREEALRRAELGQQVLWIENTIAEAQQTYLDLASRAVEAGCETGLLHSRFTPQHRNRHEQRWVALYGRAGWPQRKQCGRILVGTQVLEQSLDIDADFLVSRFAPTDMLLQRLGRLWRHTDTPRHASAKAECWLLSPSLESALANPGSAFGMSAMVYSPYVLCRSLEVWQAIPSLSLPGDIRPLIDQTYTERAEEGTWATLLHELKNGSRFRSGEQALQSLAKLTLSTGGKTLPEHKAETRYSDRDTHDLLLLRGLRTQDGITYMRLLDGAELTLPHGRHRLSRAQWRQLAVVLNQQLVRVSPAFCPPTIAKSELEKLHLQEVFYLGRPEDDEVLLRVAIVSPAGELKTLDGRPAGDKYTLEYSEYLGFRAISKKE
>NZ_CP020061.1|WP_020802906.1|1369281_1370805_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MENRFNLIDEPWIAVVDVGLVSLTDIFSQPELRALGGNPVEKIALTKLLLAIAQAAATPTDDSDWQQMGWQGMAHCCLQYLAKWHDRFYLYGEKPFLQMPAIQAAECKSLGVLSPEVSTGNTTVLTESQQQQQLTDADKALAIVMQMGFGLGGKKTDNSVVLTPGYRGKQNDKGKPGSGKAGVSVGHMGLLHSFWQGNSIVQSIWLNLFTAEDITQLAMYPTLGTAPWERMPTGEDDDIARSLKASLLGRLISMGKFCLLSEDGIHYSDGISHAGYLEGKTDPSVSVDFSGKKPKALWVNPGKRPWRELTSLLQFIEQDSPRGYETRQLSLPLKRITHHAEQFALWSGGLRVSSNAGEQYASGTDDYVQSEIWLSSDLINHTFLEYLKYEMTQLDAVQKQLWGAVVRYFRQLSDIDKSATGKAQPFVAKQAEKATTIFWQLCERQAQTLINACLTSGEDHTARLQLRKIFARYAGQVFDQLCPADSARQLDAWALARPNFSQYLTLD
>NZ_CP020061.1|WP_004180297.1|1370816_1371383_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MDQVPADVTAESAGNESPAKRFVGYVIERIAKDNGFAARLKRADNPATEYQSWEILAGFGIDLEKEWQRLPYCVIGAALAKAKPASNGTITLGAAIAGCYPEGNQSEQAKARLRRLLACTSTSEACRILRPLLALMASRSVTPDFAGLLNELQWFSGSSRERIRARWAQEFYRRAGEAAGSEARNSHD
>NZ_CP020061.1|WP_004891293.1|1371375_1372023_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTDLFASALHLDRAAVKALKISDAYSLHRVVYSLFADARTDREKCSHISSGIAYADQGGDFHGRKILIVSDRPPAAKVDGLYGEVISKSIPAAFLSHSRYRFQVQVNPVRKDKQTGKRVAVKGRADIAQWFIQRAASRWGFDVDLPGLQVEAMEVLQFKDKGGRQVTLGKATVQGLLTVTDRQKFQHSFHHGIGKGRAFGCGLLQIVPVVDALFS
>NZ_CP020061.1|WP_020802896.1|1372052_1373087_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTPFRNTRIEFHILQSFPVTCLNRDDVGAPKSAIVGGVSRARVSSQCWKRQVRLALPDFGIRLGVRSKKTASLLANACRALGASEEQATGCGEAMAAFFSDDTLLFLSEAEAAAFAAYAQGKDFDAASLKDKELVKVAKKVVNNTLDALDIALFGRMVAKAVDMNVEAAASFAHAISTHKVSNEVEFFTAVDDCKTEDESGSAHMGSLEFNSATYYRYVSLDLGQLAQTLGEDADMKTAVAAFVKALYVAVPSARQTTQSGACPWEYARVLLRKGQGLQASFEQPVKSQGEGFLSPSKAALKNWLHTKEKLSGSLFGKQGDYEWGEDLDYSIDRLIADLQSHL
>NZ_CP020061.1|WP_004180292.1|1373099_1373816_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRQTTQYMLLWLEGPLQSWGGDSKFGVRDTLNFPTRSGILGLICCARGAAGPEVEWLAEMNNLPMEVRAYARTDKEGQPLLREPTLCDFQMVGSGYDDSDPWQSLLIPKTSDGKKAVGGGTKMTYRHYLQDAVFAVVMGLGSQQAESLPEALQNPVWDLYLGRKSCVPSELIYQGIYDSAEAAWQQARTLAESKRRTLSYRVIEGEGDGDVITLNDVPVQFGRHKRYRDRQVTVLECG
>NZ_CP020061.1|WP_020802908.1|1373815_1374691_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MAQGERLFVKVTRELLPQVKDKYPFLYLERGRLEIDDSSVKWVDADGNVVPLPVATINTLLLGPGTTVTHEAIKTATAANCAVCWVGEDSLLFYAAGFLPSADTRNLKAQMALACDASSALKVARAMFAKRFPDADLEGKSLNSMMGMEGSRVRALYQQKAQEYGVGWKGRQFTPGKFELSDLTNQVLTSTNAALYGILCSVVHAMGYSPHIGFIHSGSPLPFVYDLADLYKERLCIDLAFSLSREMAGRYDKHKVSEAFRKRVIALDLLNLIAADINELMGGKGARRTGK
>NZ_CP020061.1|WP_004180288.1|1374668_1374956_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MLVVLANDLPPAVRGRMKLWFVEPRPNVFVSGVKDSVAQTVVDYLLQYTPVESGLMLFRSIPQPPGYEIRYKGEVRKPIIDLSGLQLIIETLKLS
>NZ_CP020061.1|WP_020802899.1|1375699_1376815_+|hypothetical-protein
MFRLYQSHDLIRQLNPEDFQYILTPAGSLREACIHYDLSCEANGHSLAFGLPKEIYNSSPHKRPYERRQRSYADPIYDEVEHRLQIGWLVGVDISRCWSSDRNPFYIDDNGDLIFTPTASSYHAWFKDEIMNAYRHTIADRQGRRPAPTQRIQHNYNGSRIAPASKTLNSKTIGRLLATGGIYNGNLEGFHETALQLGGDAPAGYDQIMGNKGLLIAGASFAAGLTMGRLNPLSELDELSSLSKIPAFESPYVKGFISENGTLVNAEYAVIDPKKLATYALDSTHPTGGHKARVFESALGYNPTNADVLAARIQKGVLSAPATILQTNNYGQTMAVDMPILGINGETAVIRTGWMYETDALVPRLTTIYVK
>NZ_CP020061.1|WP_020802905.1|1376825_1377509_+|DUF4926-domain-containing-protein
MKRAELDVVVLSEDLPNEGLVKGALGTIVMVFNSPTTGYLVEFCDEKGKTIAMPVLFPAQLKRYFTIRNLKSLIVEGNYPVADPVDPDVMADLMHKVAPVEWEDKKRRVYEDIQRLLISRPDYADMFNIMDGGEYNGMTLYSLVQAENGEPAWSNIFVRNFDTRINEIYVDPNLIGKVVIGEEGMSVIVYSFTDDRFEIRDKVSSDYVIESHTHFNGLLSALIEPVS

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Crispr_ID: NZ_CP020061_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020061_3

1375004-1375522

TypeI-E

I-B,III-A,III-B

Consensus_repeat	Method
GTCTTCCCCACGCACGTGGGGGTGTTTC	PILER-CR
GTCTTCCCCACGCACGTGGGGGTGTTTC	CRISPRCasFinder
GTCTTCCCCACGCACGTGGGGGTGTTTC	CRT

8 spacers

cas2,cas1,cas5,cas7,cas6e,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP020061_3

>merge|NZ_CP020061|3|1375004-1375522|PILER-CR,CRISPRCasFinder,CRT
GTCTTCCCCACGCACGTGGGGGTGTTTCTGAAGAGCTGGACCTTTGCGCCCGGCTCCAGTTGTCTTCCCCACGCACGTGGGGGTGTTTCCATATTGAAAGACGCAAACATCATGCGCCAGGTGTCTTCCCCACGCACGTGGGGGTGTTTCTATGACCCGCAGTTCCCCCAGTGGCCGGAAGAGGTCTTCCCCACGCACGTGGGGGTGTTTCTCTGCCCAATGGAACATCGATTCAGGCGACGAAGTCTTCCCCACGCACGTGGGGGTGTTTCCTCTCTGGCATGTACTGCAACGTGCAATTCAGGGTCTTCCCCACGCACGTGGTGGTGTTTCCTCGTACATGGTCTCCAGTTCGTTAGAGCGGGAGTCTTCCCCACGCACGTGGGGGTGTTTCCGAGTTCGCACACCACGATCTCGCAGGAGAGCAGTCTTGCCCACACATGTGGGGGTGTTTCCTACCGGCGCTGACTGCGCATGGCGATAGTAGATCTGTCTTCCCCATGCATGCGGGGTTTAGCA

>NZ_CP020061|3|2|1375004-1375397|PILER-CR
GTCTTCCCCACGCACGTGGGGGTGTTTC	TGAAGAGCTGGACCTTTGCGCCCGGCTCCAGTT
GTCTTCCCCACGCACGTGGGGGTGTTTC	CATATTGAAAGACGCAAACATCATGCGCCAGGT
GTCTTCCCCACGCACGTGGGGGTGTTTC	TATGACCCGCAGTTCCCCCAGTGGCCGGAAGAG
GTCTTCCCCACGCACGTGGGGGTGTTTC	TCTGCCCAATGGAACATCGATTCAGGCGACGAA
GTCTTCCCCACGCACGTGGGGGTGTTTC	CTCTCTGGCATGTACTGCAACGTGCAATTCAGG
GTCTTCCCCACGCACGTGGTGGTGTTTC	CTCGTACATGGTCTCCAGTTCGTTAGAGCGGGA
GTCTTCCCCACGCACGTGGGGGTGTTTC

>NZ_CP020061|3|3|1375004-1375522|CRISPRCasFinder
GTCTTCCCCACGCACGTGGGGGTGTTTC	TGAAGAGCTGGACCTTTGCGCCCGGCTCCAGTT
GTCTTCCCCACGCACGTGGGGGTGTTTC	CATATTGAAAGACGCAAACATCATGCGCCAGGT
GTCTTCCCCACGCACGTGGGGGTGTTTC	TATGACCCGCAGTTCCCCCAGTGGCCGGAAGAG
GTCTTCCCCACGCACGTGGGGGTGTTTC	TCTGCCCAATGGAACATCGATTCAGGCGACGAA
GTCTTCCCCACGCACGTGGGGGTGTTTC	CTCTCTGGCATGTACTGCAACGTGCAATTCAGG
GTCTTCCCCACGCACGTGGTGGTGTTTC	CTCGTACATGGTCTCCAGTTCGTTAGAGCGGGA
GTCTTCCCCACGCACGTGGGGGTGTTTC	CGAGTTCGCACACCACGATCTCGCAGGAGAGCA
GTCTTGCCCACACATGTGGGGGTGTTTC	CTACCGGCGCTGACTGCGCATGGCGATAGTAGATCT
GTCTTCCCCATGCATGCGGGGTTTAGCA

>NZ_CP020061|3|2|1375004-1375458|CRT
GTCTTCCCCACGCACGTGGGGGTGTTTC	TGAAGAGCTGGACCTTTGCGCCCGGCTCCAGTT
GTCTTCCCCACGCACGTGGGGGTGTTTC	CATATTGAAAGACGCAAACATCATGCGCCAGGT
GTCTTCCCCACGCACGTGGGGGTGTTTC	TATGACCCGCAGTTCCCCCAGTGGCCGGAAGAG
GTCTTCCCCACGCACGTGGGGGTGTTTC	TCTGCCCAATGGAACATCGATTCAGGCGACGAA
GTCTTCCCCACGCACGTGGGGGTGTTTC	CTCTCTGGCATGTACTGCAACGTGCAATTCAGG
GTCTTCCCCACGCACGTGGTGGTGTTTC	CTCGTACATGGTCTCCAGTTCGTTAGAGCGGGA
GTCTTCCCCACGCACGTGGGGGTGTTTC	CGAGTTCGCACACCACGATCTCGCAGGAGAGCA
GTCTTGCCCACACATGTGGGGGTGTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020061.1\|WP_002908285.1\|1379200_1380985_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP020061.1\|WP_004180288.1\|1374668_1374956_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|187779
NZ_CP020061.1\|WP_020802908.1\|1373815_1374691_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP020061.1\|WP_004175727.1\|1382419_1383043_+\|cytochrome-c-biogenesis-heme-transporting-ATPase-CcmA	unknown	unknown	gnl\|CDD\|184125
NZ_CP020061.1\|WP_020802902.1\|1383748_1384486_+\|heme-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|273492
NZ_CP020061.1\|WP_004194026.1\|1378445_1379198_+\|gluconate-2-dehydrogenase-subunit-3-family-protein	unknown	unknown	gnl\|CDD\|379295
NZ_CP020061.1\|WP_020802905.1\|1376825_1377509_+\|DUF4926-domain-containing-protein	unknown	unknown	gnl\|CDD\|379816
NZ_CP020061.1\|WP_004180297.1\|1370816_1371383_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP020061.1\|WP_020802899.1\|1375699_1376815_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020061.1\|WP_020802894.1\|1366662_1369278_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP020061.1\|WP_002908294.1\|1362772_1364542_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
NZ_CP020061.1\|WP_004143390.1\|1384482_1384713_+\|heme-exporter-protein-CcmD	unknown	unknown	gnl\|CDD\|225656
NZ_CP020061.1\|WP_004151164.1\|1380998_1382336_+\|cytochrome-c	unknown	unknown	gnl\|CDD\|365823
NZ_CP020061.1\|WP_004891293.1\|1371375_1372023_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|187858
NZ_CP020061.1\|WP_014907441.1\|1377569_1377941_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NZ_CP020061.1\|WP_020802906.1\|1369281_1370805_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
NZ_CP020061.1\|WP_020802896.1\|1372052_1373087_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP020061.1\|WP_004891310.1\|1383039_1383699_+\|heme-exporter-protein-CcmB	unknown	unknown	gnl\|CDD\|200083
NZ_CP020061.1\|WP_004184356.1\|1364534_1365605_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP020061.1\|WP_004180292.1\|1373099_1373816_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|273842

Protein	Function_ID	Function_description	E-value
NZ_CP020061.1\|WP_002908285.1\|1379200_1380985_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	4.91814e-80
NZ_CP020061.1\|WP_004180288.1\|1374668_1374956_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187779	cd09648, Cas2_I-E, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	6.96252e-30
NZ_CP020061.1\|WP_020802908.1\|1373815_1374691_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.04474e-119
NZ_CP020061.1\|WP_004175727.1\|1382419_1383043_+\|cytochrome-c-biogenesis-heme-transporting-ATPase-CcmA	gnl\|CDD\|184125	PRK13538, PRK13538, cytochrome c biogenesis heme-transporting ATPase CcmA.	6.65166e-109
NZ_CP020061.1\|WP_020802902.1\|1383748_1384486_+\|heme-ABC-transporter-permease	gnl\|CDD\|273492	TIGR01191, Heme_exporter_protein_C, heme exporter protein CcmC. This model describes the cyt c biogenesis protein encoded by ccmC in bacteria. It must be noted an arabidopsis, a tritcum and a piscum plant proteins were recognizable in the clade. Quite likely they are of organellar origin. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes, ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in the heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other].	1.3195e-86
NZ_CP020061.1\|WP_004143390.1\|1384482_1384713_+\|heme-exporter-protein-CcmD	gnl\|CDD\|225656	COG3114, CcmD, Heme exporter protein D [Intracellular trafficking and secretion].	3.79585e-18
NZ_CP020061.1\|WP_020802905.1\|1376825_1377509_+\|DUF4926-domain-containing-protein	gnl\|CDD\|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	4.69453e-18
NZ_CP020061.1\|WP_004180297.1\|1370816_1371383_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.02768e-28
NZ_CP020061.1\|WP_004194026.1\|1378445_1379198_+\|gluconate-2-dehydrogenase-subunit-3-family-protein	gnl\|CDD\|379295	pfam13618, Gluconate_2-dh3, Gluconate 2-dehydrogenase subunit 3. This family corresponds to subunit 3 of the Gluconate 2-dehydrogenase enzyme that catalyzes the conversion of gluconate to 2-dehydro-D-gluconate EC:1.1.99.3.	5.70236e-40
NZ_CP020061.1\|WP_020802894.1\|1366662_1369278_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	5.5709e-73
NZ_CP020061.1\|WP_002908294.1\|1362772_1364542_+\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	6.24955e-103
NZ_CP020061.1\|WP_004151164.1\|1380998_1382336_+\|cytochrome-c	gnl\|CDD\|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	1.88959e-12
NZ_CP020061.1\|WP_004891293.1\|1371375_1372023_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	2.68693e-52
NZ_CP020061.1\|WP_014907441.1\|1377569_1377941_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.34605e-41
NZ_CP020061.1\|WP_020802906.1\|1369281_1370805_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	1.27688e-74
NZ_CP020061.1\|WP_020802896.1\|1372052_1373087_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.15885e-110
NZ_CP020061.1\|WP_004891310.1\|1383039_1383699_+\|heme-exporter-protein-CcmB	gnl\|CDD\|200083	TIGR01190, Heme_exporter_protein_B, heme exporter protein CcmB. This model describes the cyt c biogenesis protein encoded by ccmB in bacteria. Bacterial c-type cytochromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome C. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other].	8.31009e-72
NZ_CP020061.1\|WP_004184356.1\|1364534_1365605_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	2.11253e-144
NZ_CP020061.1\|WP_004180292.1\|1373099_1373816_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	5.1815e-54

>NZ_CP020061.1|WP_004180288.1|1374668_1374956_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MLVVLANDLPPAVRGRMKLWFVEPRPNVFVSGVKDSVAQTVVDYLLQYTPVESGLMLFRSIPQPPGYEIRYKGEVRKPIIDLSGLQLIIETLKLS
>NZ_CP020061.1|WP_020802908.1|1373815_1374691_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MAQGERLFVKVTRELLPQVKDKYPFLYLERGRLEIDDSSVKWVDADGNVVPLPVATINTLLLGPGTTVTHEAIKTATAANCAVCWVGEDSLLFYAAGFLPSADTRNLKAQMALACDASSALKVARAMFAKRFPDADLEGKSLNSMMGMEGSRVRALYQQKAQEYGVGWKGRQFTPGKFELSDLTNQVLTSTNAALYGILCSVVHAMGYSPHIGFIHSGSPLPFVYDLADLYKERLCIDLAFSLSREMAGRYDKHKVSEAFRKRVIALDLLNLIAADINELMGGKGARRTGK
>NZ_CP020061.1|WP_004180292.1|1373099_1373816_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRQTTQYMLLWLEGPLQSWGGDSKFGVRDTLNFPTRSGILGLICCARGAAGPEVEWLAEMNNLPMEVRAYARTDKEGQPLLREPTLCDFQMVGSGYDDSDPWQSLLIPKTSDGKKAVGGGTKMTYRHYLQDAVFAVVMGLGSQQAESLPEALQNPVWDLYLGRKSCVPSELIYQGIYDSAEAAWQQARTLAESKRRTLSYRVIEGEGDGDVITLNDVPVQFGRHKRYRDRQVTVLECG
>NZ_CP020061.1|WP_020802896.1|1372052_1373087_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTPFRNTRIEFHILQSFPVTCLNRDDVGAPKSAIVGGVSRARVSSQCWKRQVRLALPDFGIRLGVRSKKTASLLANACRALGASEEQATGCGEAMAAFFSDDTLLFLSEAEAAAFAAYAQGKDFDAASLKDKELVKVAKKVVNNTLDALDIALFGRMVAKAVDMNVEAAASFAHAISTHKVSNEVEFFTAVDDCKTEDESGSAHMGSLEFNSATYYRYVSLDLGQLAQTLGEDADMKTAVAAFVKALYVAVPSARQTTQSGACPWEYARVLLRKGQGLQASFEQPVKSQGEGFLSPSKAALKNWLHTKEKLSGSLFGKQGDYEWGEDLDYSIDRLIADLQSHL
>NZ_CP020061.1|WP_004891293.1|1371375_1372023_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTDLFASALHLDRAAVKALKISDAYSLHRVVYSLFADARTDREKCSHISSGIAYADQGGDFHGRKILIVSDRPPAAKVDGLYGEVISKSIPAAFLSHSRYRFQVQVNPVRKDKQTGKRVAVKGRADIAQWFIQRAASRWGFDVDLPGLQVEAMEVLQFKDKGGRQVTLGKATVQGLLTVTDRQKFQHSFHHGIGKGRAFGCGLLQIVPVVDALFS
>NZ_CP020061.1|WP_004180297.1|1370816_1371383_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MDQVPADVTAESAGNESPAKRFVGYVIERIAKDNGFAARLKRADNPATEYQSWEILAGFGIDLEKEWQRLPYCVIGAALAKAKPASNGTITLGAAIAGCYPEGNQSEQAKARLRRLLACTSTSEACRILRPLLALMASRSVTPDFAGLLNELQWFSGSSRERIRARWAQEFYRRAGEAAGSEARNSHD
>NZ_CP020061.1|WP_020802906.1|1369281_1370805_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MENRFNLIDEPWIAVVDVGLVSLTDIFSQPELRALGGNPVEKIALTKLLLAIAQAAATPTDDSDWQQMGWQGMAHCCLQYLAKWHDRFYLYGEKPFLQMPAIQAAECKSLGVLSPEVSTGNTTVLTESQQQQQLTDADKALAIVMQMGFGLGGKKTDNSVVLTPGYRGKQNDKGKPGSGKAGVSVGHMGLLHSFWQGNSIVQSIWLNLFTAEDITQLAMYPTLGTAPWERMPTGEDDDIARSLKASLLGRLISMGKFCLLSEDGIHYSDGISHAGYLEGKTDPSVSVDFSGKKPKALWVNPGKRPWRELTSLLQFIEQDSPRGYETRQLSLPLKRITHHAEQFALWSGGLRVSSNAGEQYASGTDDYVQSEIWLSSDLINHTFLEYLKYEMTQLDAVQKQLWGAVVRYFRQLSDIDKSATGKAQPFVAKQAEKATTIFWQLCERQAQTLINACLTSGEDHTARLQLRKIFARYAGQVFDQLCPADSARQLDAWALARPNFSQYLTLD
>NZ_CP020061.1|WP_020802894.1|1366662_1369278_+|CRISPR-associated-helicase-Cas3'
MRRLIRVSLQNQHAIAAISFENCPAKTRMLSDGRVVQGRSVLSHCQIVGEIARALIALYPEPMRSRLFPAGSEMAAAGHDIGKVSPTFAAKIFAACDVNDHRLAGLSAVNPGLETLWGGHAGVSQATAESLHAPRYVPEILGQHHGFNPGLNGRRGDAEVFGGPLWFDERKKLVDKLKAEFSADWPTFDSAAQARVVAGLTSVADWIGSGEFFENPEQAWQPVITAALNNAGFIKPVIRQGLSFADVFFPDDPSKKPREAQSRFIDQVVGPGLYILEAKMGMGKTEAALYAAYQMLLQEKATGIYFALPTQLTSNKIYDRFNAFLHQIVSTETPQHALLLHSGAWLMDTEMGEEGSPGGAWFNHRKRGLLAPFAVGTIDQALMAVMNVKHGFVRAYGLAGKVVILDEVHTYDLYTGTILNALVEFLRQIDCTVIILSATLSQTRRDALLQQSTTSEAYPLITAAPSAERERGLVEISVPVTENTTVILHSCRKDESAREEALRRAELGQQVLWIENTIAEAQQTYLDLASRAVEAGCETGLLHSRFTPQHRNRHEQRWVALYGRAGWPQRKQCGRILVGTQVLEQSLDIDADFLVSRFAPTDMLLQRLGRLWRHTDTPRHASAKAECWLLSPSLESALANPGSAFGMSAMVYSPYVLCRSLEVWQAIPSLSLPGDIRPLIDQTYTERAEEGTWATLLHELKNGSRFRSGEQALQSLAKLTLSTGGKTLPEHKAETRYSDRDTHDLLLLRGLRTQDGITYMRLLDGAELTLPHGRHRLSRAQWRQLAVVLNQQLVRVSPAFCPPTIAKSELEKLHLQEVFYLGRPEDDEVLLRVAIVSPAGELKTLDGRPAGDKYTLEYSEYLGFRAISKKE
>NZ_CP020061.1|WP_004184356.1|1364534_1365605_+|ABC-transporter-ATP-binding-protein
MIELSVENLHLTYGDNPVLKGVSMTLGRGEVVSLLGPSGSGKTTLLRAVAGLEKPTSGRIAIGNRTVYDGTPRSEIPAEERNLGLVFQSYALWPHKTVFDNVAYPLKLRKVAAGEIKERVQRVLDQLGLGHLGNRHPHQLSGGQQQRVAIGRALVYNPPVILLDEPLSNLDAKLREEARVFLRELIIKLGLSALMVTHDQNEAMAISDRILLLNNGVIEQQGTPQEMYGSPATLFAAEFMGSNNRLHGKVMALENGRARIEGASWSLWGRAGEGVSVGEPATAVIRVERLRLDGAAQDNSLQLPLLTSMYLGDRWEYLFRTEGDDFPLRAYGTALRDAEHCHLTLPAEDVWIFPQQ
>NZ_CP020061.1|WP_002908294.1|1362772_1364542_+|iron-ABC-transporter-permease
MNVLRRKWQGLPRGVVVCITALVIYVPLLFIVVQSFLSAPFFSRSKSWSLEAFAFIFTDPDFYLALRSGFILAFGLVIIAIPLGGILAFLMVRTDLPGRRIIEPLILVPIFVSPMVLGFGYVVAAGPVGFFSQWAQQLIGFVPWNIYSMFSIVVIAGLTHVPHAYLYISSALRSVGSDVEEAARTVGATPLQVMTSVSLPMVRPSILYACVLLFFLGLEVFGLMLVLGDPEGNMVLATYLYKLTNKLGTPSYHLMAAVAVVLICITIPLVMLQRRLMRTANRFVTMKGKASQARALPLGKWRWVAGAVVVAWLTVTIGVPLLGVALRAFISNWGVGVSLWDELSLATFHNIWQQPNLLRAIVNSMAIGIIGGALAVICYLFVGIAMHRKADNVTRFLDYSVLVPRAVPGLLAGLAFLWVFLFVPMWLDQSLKHGWLSALPVADWLREHLIVQLRALRNTIFSVWLAYTVVWMAYGLRLISSTLLQVGPELEEAARSTGASRGQITRHVTVPLSRYGLIGSWLLMFLIFEREYSTGVYLLSPGTETIGSMLVSLWAAGAIDIVAALSFINILLVVIGLGIALRFGVKLHD
>NZ_CP020061.1|WP_020802899.1|1375699_1376815_+|hypothetical-protein
MFRLYQSHDLIRQLNPEDFQYILTPAGSLREACIHYDLSCEANGHSLAFGLPKEIYNSSPHKRPYERRQRSYADPIYDEVEHRLQIGWLVGVDISRCWSSDRNPFYIDDNGDLIFTPTASSYHAWFKDEIMNAYRHTIADRQGRRPAPTQRIQHNYNGSRIAPASKTLNSKTIGRLLATGGIYNGNLEGFHETALQLGGDAPAGYDQIMGNKGLLIAGASFAAGLTMGRLNPLSELDELSSLSKIPAFESPYVKGFISENGTLVNAEYAVIDPKKLATYALDSTHPTGGHKARVFESALGYNPTNADVLAARIQKGVLSAPATILQTNNYGQTMAVDMPILGINGETAVIRTGWMYETDALVPRLTTIYVK
>NZ_CP020061.1|WP_020802905.1|1376825_1377509_+|DUF4926-domain-containing-protein
MKRAELDVVVLSEDLPNEGLVKGALGTIVMVFNSPTTGYLVEFCDEKGKTIAMPVLFPAQLKRYFTIRNLKSLIVEGNYPVADPVDPDVMADLMHKVAPVEWEDKKRRVYEDIQRLLISRPDYADMFNIMDGGEYNGMTLYSLVQAENGEPAWSNIFVRNFDTRINEIYVDPNLIGKVVIGEEGMSVIVYSFTDDRFEIRDKVSSDYVIESHTHFNGLLSALIEPVS
>NZ_CP020061.1|WP_014907441.1|1377569_1377941_-|VOC-family-protein
MFDHVKFGVSDYAASKAFFLQALAPLGVTLVGEGEPSYGAELAGSGDASLCLYQSAEKPAPLHIAFRADSREQVDAFWQAALAAGGKDNGAPGLRLNYHASYYAAFVIAPDGHNIEAVCHLAG
>NZ_CP020061.1|WP_004194026.1|1378445_1379198_+|gluconate-2-dehydrogenase-subunit-3-family-protein
MSSEKTNNSRRDFLVKSMALIPTVVIGGAGAGAIGVATSATAQAAPASEPASGNTAAASDWKPQFFNDREWAFINAAVARLIPADELGPGAKEAGVPEFIDRQLNTPYATGSIWYMQGPFNPDVPKEMGYQLPLVPKQIYNLGIADAEAWCQDKYHKTFAELSSEQQDEALGLWESGKAEFKQLPASLFFTYLLQNTREGFFSDPIHGGNKGMVGWTLINFPGARADFMDWVERGERYPFPPVSINGERA
>NZ_CP020061.1|WP_002908285.1|1379200_1380985_+|GMC-family-oxidoreductase
MATVLKKTDVAIVGFGWVGAIMAKELTEAGLNVVALERGPMRDTWPDGAYPQVIDELTYNIRRKLFQDLSKSTVTIRHNTSQQAVPYRQLAAFLPGTGVGGAGLHWSGVHFRVDPIELRMRSHYEERYGKNFIPQDMIIQDFGVTYDELEPFFDKAEKVFGTSGTAWSIKGKVVGKGRGGNAFAPDRSDDFPLPAQKNTWSAQLFEKAALEVGYHPYNLPSANTSDSYTNPYGAQMGPCNFCGFCSGYACYMYSKASPNVNILPALRQEKRFELRTNANVLKVNLTDDKSRATGVTYVDGQGREMEQPADLVIIGAFQFHNVHLMLLSGIGKPYNPETGEGVVGRNFAYQNMTTIKAIFDKDTYTNPFIGAGGNGVGVDDFNADNFDHGAAGFVGGSPFWVNQAGTKPISGFPVPPGTPAWGSKWKAAVADTYTHHLSMDAHGAHQSYRQNYLDLDPNYKNVFGQPLLRMTFDWQENDIKMAQFMFDKMAPIAKAMKPKYILGSPKNANSHFDTTTYQTTHMNGGAVMGEDPKTSAVNRYLQSWDVHNVFVIGASAFPQGLGYNPTGTVAALAYWSAKAIREQYLKNPGPLVQA
>NZ_CP020061.1|WP_004151164.1|1380998_1382336_+|cytochrome-c
MKMQWLSALVLGALSCAAFAEEAPADSNLIKQGEYLARAGDCVACHTNGKAGKPFAGGLPMETPIGTIYSTNITPDKEHGIGGYTFEEFDDAVRKGVRKDGSTLYPAMPYPSFARISEADMRAMYAYFMHGVEPVNVANKDTDIPWPLSMRWPLAFWRGIFAPTPSDFVANPQVDPVLERGRYLVEGLGHCGACHTPRSLTMQEKALSESEGDDYLAGSNAPIDGWVASSLRGENRDGLGTWSEAELAEFLKTGRNDKSVVFGGMSDVVEHSLQYLSDDDITAIARYLKSLPPRGGKQTPAPVEDSVAKDLWKGNDSKTGAALYVDNCAACHRTDGAGYKRAFPSLKGNPVVQTEDATSLIHIVLTGSTTPAVKDAVSNLTMPSFGWRLDDQQVADVVNFIRTSWGNNAPAVSASDVAKVRKETAAHDEKALGNADISKLPGAGQ
>NZ_CP020061.1|WP_004175727.1|1382419_1383043_+|cytochrome-c-biogenesis-heme-transporting-ATPase-CcmA
MLHAERLTCIVDDRPLFAALTLSLAAGELLQIAGDNGAGKTSLLRILCGLARPESGVVSWQGQPLAKVRESFHRQLLWLGHKPGVNAALTADENLRFFFPASRLQQRESALAAVGLAGYEDLPLSQLSAGQQRRVALTRLWLTDAPLWILDEPFTALDATAMETLTRRLEQHARQGGCAILTTHQPLRPLGCPLRTLRLGGDAGGGQ
>NZ_CP020061.1|WP_004891310.1|1383039_1383699_+|heme-exporter-protein-CcmB
MMRALLARELRLAWRSGAEILNPLWFFLIVITLFPFGVGAAPQLLAQIAPGVVWVAALLAALLVMDRLFRDDWQDGSLEQLMLLPTPLVAVVLVKVVAHWMMSGLPLLIVSPLAALLLGMSLHDAGVLALTLLLGTPTLSFLGAVGVGLTVGLKRGGVLLSLLVLPLAVPLLIFATAACQAAAAGLPVSGYLAMLAAFLTASATLCPFATAAALRLTVR
>NZ_CP020061.1|WP_020802902.1|1383748_1384486_+|heme-ABC-transporter-permease
MWKALHQLAIPERLYRLCGCWIPWLAALSALLLVIGLGWGFGFAPADYQQGESYRIMYLHVPTAMWSMGLYLAMAVAAFVGVVWQIKMADLANAALAPVGAVCTLVALVSGAAWGKPMWGTWWIWDARLTSELVLLFLYAGVIALWHAFDDRRLAGRAAGILVLVGVVNLPIIHYSVYWWNTLHQGSTNLQQTIDPSMRLPLRICIFAFLTLSVTLTLMRLRNLILQLERRRPWVVALVNKGAAR
>NZ_CP020061.1|WP_004143390.1|1384482_1384713_+|heme-exporter-protein-CcmD
MSPAFSSFAAFLNMGGYAVYVWLAVAVTVAAFGLLTVHTLWARRALFHEVRRQQARERRIAAAREHDKEAADASAS

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Crispr_ID: NZ_CP020061_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020061_4

3521835-3521929

Orphan

Consensus_repeat	Method
ACTATGGTTTTTATGGTTTTTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020061_4

>merge|NZ_CP020061|4|3521835-3521929|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATGGTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATGACTGTGGTTTTTATGGTTTTTATT

>NZ_CP020061|4|4|3521835-3521929|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATG	GTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATG
ACTGTGGTTTTTATGGTTTTTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020061.1\|WP_004177424.1\|3510953_3512456_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP020061.1\|WP_004145980.1\|3518928_3519588_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP020061.1\|WP_004178574.1\|3516009_3518916_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP020061.1\|WP_004182906.1\|3523685_3524384_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP020061.1\|WP_002888329.1\|3527890_3529177_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP020061.1\|WP_002888340.1\|3522070_3523696_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP020061.1\|WP_002888332.1\|3524416_3525244_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP020061.1\|WP_004147026.1\|3525487_3527836_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP020061.1\|WP_016531719.1\|3512593_3513289_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP020061.1\|WP_004145972.1\|3508050_3508896_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP020061.1\|WP_020802819.1\|3509233_3510943_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP020061.1\|WP_032447861.1\|3519662_3520202_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP020061.1\|WP_020802788.1\|3530168_3530990_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP020061.1\|WP_002888373.1\|3507154_3507922_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP020061.1\|WP_002888320.1\|3532478_3532958_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP020061.1\|WP_002888321.1\|3531374_3532223_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP020061.1\|WP_002888323.1\|3530992_3531370_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP020061.1\|WP_002888327.1\|3529182_3530172_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP020061.1\|WP_002888345.1\|3520381_3521746_-\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP020061.1\|WP_020802825.1\|3513464_3515822_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595

Protein	Function_ID	Function_description	E-value
NZ_CP020061.1\|WP_004177424.1\|3510953_3512456_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP020061.1\|WP_004145980.1\|3518928_3519588_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	7.90078e-161
NZ_CP020061.1\|WP_004178574.1\|3516009_3518916_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP020061.1\|WP_004182906.1\|3523685_3524384_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.65624e-65
NZ_CP020061.1\|WP_002888329.1\|3527890_3529177_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP020061.1\|WP_002888340.1\|3522070_3523696_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	6.55037e-173
NZ_CP020061.1\|WP_002888332.1\|3524416_3525244_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
NZ_CP020061.1\|WP_004147026.1\|3525487_3527836_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP020061.1\|WP_016531719.1\|3512593_3513289_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP020061.1\|WP_004145972.1\|3508050_3508896_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP020061.1\|WP_020802819.1\|3509233_3510943_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP020061.1\|WP_032447861.1\|3519662_3520202_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.13516e-86
NZ_CP020061.1\|WP_020802788.1\|3530168_3530990_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.77261e-147
NZ_CP020061.1\|WP_002888373.1\|3507154_3507922_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP020061.1\|WP_002888320.1\|3532478_3532958_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
NZ_CP020061.1\|WP_002888321.1\|3531374_3532223_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP020061.1\|WP_002888323.1\|3530992_3531370_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
NZ_CP020061.1\|WP_002888327.1\|3529182_3530172_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP020061.1\|WP_002888345.1\|3520381_3521746_-\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
NZ_CP020061.1\|WP_020802825.1\|3513464_3515822_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0

>NZ_CP020061.1|WP_002888345.1|3520381_3521746_-|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP020061.1|WP_032447861.1|3519662_3520202_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIEALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLMWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>NZ_CP020061.1|WP_004145980.1|3518928_3519588_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPMQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP020061.1|WP_004178574.1|3516009_3518916_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESTDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAAIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP020061.1|WP_020802825.1|3513464_3515822_+|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLNIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSDVNAWWAQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP020061.1|WP_016531719.1|3512593_3513289_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQRIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP020061.1|WP_004177424.1|3510953_3512456_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATAEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP020061.1|WP_020802819.1|3509233_3510943_+|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQTVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSQAALTH
>NZ_CP020061.1|WP_004145972.1|3508050_3508896_-|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVRDACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP020061.1|WP_002888373.1|3507154_3507922_-|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR
>NZ_CP020061.1|WP_002888340.1|3522070_3523696_+|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEAHDAS
>NZ_CP020061.1|WP_004182906.1|3523685_3524384_+|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSGREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP020061.1|WP_002888332.1|3524416_3525244_-|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP020061.1|WP_004147026.1|3525487_3527836_+|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP020061.1|WP_002888329.1|3527890_3529177_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP020061.1|WP_002888327.1|3529182_3530172_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP020061.1|WP_020802788.1|3530168_3530990_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHRTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP020061.1|WP_002888323.1|3530992_3531370_+|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP020061.1|WP_002888321.1|3531374_3532223_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP020061.1|WP_002888320.1|3532478_3532958_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP020061_3	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	NZ_CP020061.1	479100-479132	1	0.97

1. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to position: 479100-479132, mismatch: 1, identity: 0.97

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgacccgcagttcacccagtggccggaagag	Protospacer
*************** *****************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020061_2	2.2\|1365946\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1365946-1365978	33	MT939253	Klebsiella phage vB_KpnM_Seu621, complete genome	118529-118561	2	0.939
NZ_CP020061_2	2.2\|1365946\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1365946-1365978	33	NC_048682	Raoultella phage Ro1, complete genome	25734-25766	2	0.939
NZ_CP020061_2	2.2\|1365946\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1365946-1365978	33	MK024806	Proteus phage Mydo, complete genome	33627-33659	2	0.939
NZ_CP020061_3	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	LR134277	Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 2	7026-7058	2	0.939
NZ_CP020061_3	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	LR134279	Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 4	11052-11084	2	0.939
NZ_CP020061_3	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	LR134281	Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 6	18109-18141	2	0.939
NZ_CP020061_3	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	LR134278	Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 3	13172-13204	2	0.939
NZ_CP020061_2	2.5\|1366129\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366129-1366161	33	NZ_CP014649	Klebsiella pneumoniae strain KPNIH36 plasmid pKPN-fff, complete sequence	32906-32938	3	0.909
NZ_CP020061_2	2.5\|1366129\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366129-1366161	33	NZ_CP037929	Klebsiella pneumoniae subsp. pneumoniae strain KP-8788 plasmid pKPN-IT-8788, complete sequence	236854-236886	3	0.909
NZ_CP020061_2	2.5\|1366129\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366129-1366161	33	MN922301	Klebsiella pneumoniae strain KP-14159 plasmid pKPN-IT-14159, complete sequence	236854-236886	3	0.909
NZ_CP020061_2	2.5\|1366129\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366129-1366161	33	MK416010	Klebsiella phage ST11-OXA245phi3.2, complete genome	12139-12171	3	0.909
NZ_CP020061_2	2.5\|1366129\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366129-1366161	33	NZ_CP007729	Klebsiella pneumoniae subsp. pneumoniae KPNIH10 plasmid pKPN-498, complete sequence	173038-173070	3	0.909
NZ_CP020061_3	3.2\|1375093\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375093-1375125	33	MF459647	Erwinia phage vB_EamM_Joad, complete genome	113796-113828	6	0.818
NZ_CP020061_3	3.2\|1375093\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375093-1375125	33	MF459646	Erwinia phage vB_EamM_RisingSun, complete genome	113873-113905	6	0.818
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	KY271396	Klebsiella phage 2 LV-2017, complete genome	29891-29926	6	0.833
NZ_CP020061_2	2.4\|1366068\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366068-1366100	33	MN095770	Serratia phage Slocum, complete genome	82795-82827	7	0.788
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NC_021654	Klebsiella pneumoniae plasmid pKN-LS6, complete sequence	189431-189466	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NZ_CP007729	Klebsiella pneumoniae subsp. pneumoniae KPNIH10 plasmid pKPN-498, complete sequence	154005-154040	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NZ_CP024517	Klebsiella pneumoniae strain KSB1_10J plasmid unnamed2, complete sequence	14109-14144	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NZ_CP024497	Klebsiella pneumoniae strain KSB1_7E plasmid unnamed1, complete sequence	14109-14144	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NZ_CP024501	Klebsiella pneumoniae strain KSB1_4E plasmid unnamed2, complete sequence	14109-14144	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	KY271395	Klebsiella phage 2b LV-2017, complete genome	14816-14851	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	MK422448	Klebsiella phage ST512-KPC3phi13.3, complete genome	29778-29813	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NZ_CP014649	Klebsiella pneumoniae strain KPNIH36 plasmid pKPN-fff, complete sequence	51936-51971	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NZ_CP048109	Klebsiella michiganensis strain BD177 plasmid unnamed1	160569-160604	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NZ_CP037929	Klebsiella pneumoniae subsp. pneumoniae strain KP-8788 plasmid pKPN-IT-8788, complete sequence	255884-255919	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	MN922301	Klebsiella pneumoniae strain KP-14159 plasmid pKPN-IT-14159, complete sequence	255884-255919	7	0.806
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	JF974294	Aeromonas phage pIS4-A genomic sequence	3104-3139	8	0.778
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	NC_021534	Vibrio phage pYD38-A genomic sequence	22156-22191	8	0.778
NZ_CP020061_2	2.1\|1365885\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1365885-1365917	33	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	503140-503172	9	0.727
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	MK416010	Klebsiella phage ST11-OXA245phi3.2, complete genome	31565-31600	9	0.75
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	MK448237	Klebsiella phage ST974-OXA48phi18.2, complete genome	22877-22912	9	0.75
NZ_CP020061_2	2.1\|1365885\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1365885-1365917	33	MH588547	Caulobacter phage CcrSC, complete genome	239029-239061	10	0.697
NZ_CP020061_2	2.3\|1366007\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366007-1366039	33	MG592468	Vibrio phage 1.094.O._10N.286.55.E12, partial genome	46660-46692	10	0.697
NZ_CP020061_2	2.3\|1366007\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366007-1366039	33	MG592451	Vibrio phage 1.075.O._10N.286.55.B10, partial genome	46755-46787	10	0.697
NZ_CP020061_2	2.3\|1366007\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366007-1366039	33	MG592467	Vibrio phage 1.093.O._10N.286.55.E10, partial genome	46762-46794	10	0.697
NZ_CP020061_2	2.3\|1366007\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1366007-1366039	33	MG592401	Vibrio phage 1.017.O._10N.286.55.C11, partial genome	46697-46729	10	0.697
NZ_CP020061_3	3.8\|1375459\|36\|NZ_CP020061\|CRISPRCasFinder	1375459-1375494	36	MK416013	Klebsiella phage ST16-OXA48phi5.1, complete genome	28158-28193	10	0.722

1. spacer 2.2|1365946|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MT939253 (Klebsiella phage vB_KpnM_Seu621, complete genome) position: , mismatch: 2, identity: 0.939

tatagtatgacgattgattccactcatcaattt	CRISPR spacer
tatagtatgatgattgattccattcatcaattt	Protospacer
**********.***********.**********

2. spacer 2.2|1365946|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NC_048682 (Raoultella phage Ro1, complete genome) position: , mismatch: 2, identity: 0.939

tatagtatgacgattgattccactcatcaattt	CRISPR spacer
tatagtatgatgattgattccattcatcaattt	Protospacer
**********.***********.**********

3. spacer 2.2|1365946|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MK024806 (Proteus phage Mydo, complete genome) position: , mismatch: 2, identity: 0.939

tatagtatgacgattgattccactcatcaattt	CRISPR spacer
tatagtatgatgattgattccattcatcaattt	Protospacer
**********.***********.**********

4. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to LR134277 (Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 2) position: , mismatch: 2, identity: 0.939

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgatccgcagttcacccagtggccggaagag	Protospacer
*****.********* *****************

5. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to LR134279 (Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 4) position: , mismatch: 2, identity: 0.939

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgatccgcagttcacccagtggccggaagag	Protospacer
*****.********* *****************

6. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to LR134281 (Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 6) position: , mismatch: 2, identity: 0.939

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgatccgcagttcacccagtggccggaagag	Protospacer
*****.********* *****************

7. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to LR134278 (Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 3) position: , mismatch: 2, identity: 0.939

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgacccgcaattcacccagtggccggaagag	Protospacer
***********.*** *****************

8. spacer 2.5|1366129|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014649 (Klebsiella pneumoniae strain KPNIH36 plasmid pKPN-fff, complete sequence) position: , mismatch: 3, identity: 0.909

ttttcgaacgtcatcgacggcttttagcattta	CRISPR spacer
ttttcgaacgtcatcgccggctttgagcatttc	Protospacer
**************** ******* *******

9. spacer 2.5|1366129|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037929 (Klebsiella pneumoniae subsp. pneumoniae strain KP-8788 plasmid pKPN-IT-8788, complete sequence) position: , mismatch: 3, identity: 0.909

ttttcgaacgtcatcgacggcttttagcattta	CRISPR spacer
ttttcgaacgtcatcgccggctttgagcatttc	Protospacer
**************** ******* *******

10. spacer 2.5|1366129|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MN922301 (Klebsiella pneumoniae strain KP-14159 plasmid pKPN-IT-14159, complete sequence) position: , mismatch: 3, identity: 0.909

ttttcgaacgtcatcgacggcttttagcattta	CRISPR spacer
ttttcgaacgtcatcgccggctttgagcatttc	Protospacer
**************** ******* *******

11. spacer 2.5|1366129|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MK416010 (Klebsiella phage ST11-OXA245phi3.2, complete genome) position: , mismatch: 3, identity: 0.909

ttttcgaacgtcatcgacggcttttagcattta	CRISPR spacer
ttttcgaacgtcatcgccggctttgagcatttc	Protospacer
**************** ******* *******

12. spacer 2.5|1366129|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007729 (Klebsiella pneumoniae subsp. pneumoniae KPNIH10 plasmid pKPN-498, complete sequence) position: , mismatch: 3, identity: 0.909

ttttcgaacgtcatcgacggcttttagcattta	CRISPR spacer
ttttcgaacgtcatcgccggctttgagcatttc	Protospacer
**************** ******* *******

13. spacer 3.2|1375093|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MF459647 (Erwinia phage vB_EamM_Joad, complete genome) position: , mismatch: 6, identity: 0.818

catattgaaagacgcaaacatca-tgcgccaggt	CRISPR spacer
catattcaaagacgcaaacatcattgcgctgaa-	Protospacer
****** **************** *****....

14. spacer 3.2|1375093|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MF459646 (Erwinia phage vB_EamM_RisingSun, complete genome) position: , mismatch: 6, identity: 0.818

catattgaaagacgcaaacatca-tgcgccaggt	CRISPR spacer
catattcaaagacgcaaacatcattgcgctgaa-	Protospacer
****** **************** *****....

15. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to KY271396 (Klebsiella phage 2 LV-2017, complete genome) position: , mismatch: 6, identity: 0.833

ctaccggcgctgactgcgcatggcgatag----tagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcttag----	Protospacer
************.******.*********    ***

16. spacer 2.4|1366068|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MN095770 (Serratia phage Slocum, complete genome) position: , mismatch: 7, identity: 0.788

ctgtttcattcgctccgatggctcgatctccgc	CRISPR spacer
ttggttcattcgctctgatggctcgactacctc	Protospacer
.** ***********.**********.. ** *

17. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NC_021654 (Klebsiella pneumoniae plasmid pKN-LS6, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcggct	Protospacer
************.******.********* . . **

18. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NZ_CP007729 (Klebsiella pneumoniae subsp. pneumoniae KPNIH10 plasmid pKPN-498, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcggct	Protospacer
************.******.********* . . **

19. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NZ_CP024517 (Klebsiella pneumoniae strain KSB1_10J plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcttcg	Protospacer
************.******.********* .  **

20. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NZ_CP024497 (Klebsiella pneumoniae strain KSB1_7E plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcttcg	Protospacer
************.******.********* .  **

21. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NZ_CP024501 (Klebsiella pneumoniae strain KSB1_4E plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcttcg	Protospacer
************.******.********* .  **

22. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to KY271395 (Klebsiella phage 2b LV-2017, complete genome) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatag---tagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagctggg---	Protospacer
************.******.*********   *.*.

23. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to MK422448 (Klebsiella phage ST512-KPC3phi13.3, complete genome) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcggct	Protospacer
************.******.********* . . **

24. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NZ_CP014649 (Klebsiella pneumoniae strain KPNIH36 plasmid pKPN-fff, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcggct	Protospacer
************.******.********* . . **

25. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NZ_CP048109 (Klebsiella michiganensis strain BD177 plasmid unnamed1) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcttcg	Protospacer
************.******.********* .  **

26. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NZ_CP037929 (Klebsiella pneumoniae subsp. pneumoniae strain KP-8788 plasmid pKPN-IT-8788, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcggct	Protospacer
************.******.********* . . **

27. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to MN922301 (Klebsiella pneumoniae strain KP-14159 plasmid pKPN-IT-14159, complete sequence) position: , mismatch: 7, identity: 0.806

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcggct	Protospacer
************.******.********* . . **

28. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to JF974294 (Aeromonas phage pIS4-A genomic sequence) position: , mismatch: 8, identity: 0.778

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagaggcg	Protospacer
************.******.********* ... *

29. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to NC_021534 (Vibrio phage pYD38-A genomic sequence) position: , mismatch: 8, identity: 0.778

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagaggcg	Protospacer
************.******.********* ... *

30. spacer 2.1|1365885|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 9, identity: 0.727

cgagctcatcgcctccctggagacggcgggcga	CRISPR spacer
ccgccgggtcgccaccctggagacggctggcgc	Protospacer
* . *  .***** ************* ****

31. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to MK416010 (Klebsiella phage ST11-OXA245phi3.2, complete genome) position: , mismatch: 9, identity: 0.75

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ctaccggcgctggctgcgcgtggcgatagagcggag	Protospacer
************.******.********* . .

32. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to MK448237 (Klebsiella phage ST974-OXA48phi18.2, complete genome) position: , mismatch: 9, identity: 0.75

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
ttaccggcgctggctgcgcgtggcgatagagcgtga	Protospacer
.***********.******.********* . .*

33. spacer 2.1|1365885|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MH588547 (Caulobacter phage CcrSC, complete genome) position: , mismatch: 10, identity: 0.697

cgagctcatcgcctccctggagacggcgggcga	CRISPR spacer
gcggctgatcgccaccctggagacggccttggg	Protospacer
  .*** ****** *************    *.

34. spacer 2.3|1366007|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MG592468 (Vibrio phage 1.094.O._10N.286.55.E12, partial genome) position: , mismatch: 10, identity: 0.697

caagacacctgcaaacggtatatctttggagtg	CRISPR spacer
tttgacaccttcaaacggcatatcttttttagg	Protospacer
.  ******* *******.********   . *

35. spacer 2.3|1366007|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MG592451 (Vibrio phage 1.075.O._10N.286.55.B10, partial genome) position: , mismatch: 10, identity: 0.697

caagacacctgcaaacggtatatctttggagtg	CRISPR spacer
tttgacaccttcaaacggcatatcttttttagg	Protospacer
.  ******* *******.********   . *

36. spacer 2.3|1366007|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MG592467 (Vibrio phage 1.093.O._10N.286.55.E10, partial genome) position: , mismatch: 10, identity: 0.697

caagacacctgcaaacggtatatctttggagtg	CRISPR spacer
tttgacaccttcaaacggcatatcttttttagg	Protospacer
.  ******* *******.********   . *

37. spacer 2.3|1366007|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to MG592401 (Vibrio phage 1.017.O._10N.286.55.C11, partial genome) position: , mismatch: 10, identity: 0.697

caagacacctgcaaacggtatatctttggagtg	CRISPR spacer
tttgacaccttcaaacggcatatcttttttagg	Protospacer
.  ******* *******.********   . *

38. spacer 3.8|1375459|36|NZ_CP020061|CRISPRCasFinder matches to MK416013 (Klebsiella phage ST16-OXA48phi5.1, complete genome) position: , mismatch: 10, identity: 0.722

ctaccggcgctgactgcgcatggcgatagtagatct	CRISPR spacer
attccggcgctggctgcgcgtggcgatagagcggca	Protospacer
 * *********.******.********* . . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

419754 : 504536

Enterobacteria_phage(16.0%)

integrase,protease,holin,head,tRNA,capsid,tail,terminase,portal,transposase

attL 442762:442785|attR 481783:481806

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016947271.1\|419754_421173_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_002913435.1\|421224_421617_-	putative DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_002913434.1\|421620_421974_-	putative DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_004151096.1\|422595_424767_+	EAL domain-containing protein	NA	NA	NA	NA
WP_002913423.1\|424815_426018_-	nucleoside permease NupC	NA	NA	NA	NA
WP_002913421.1\|426364_427606_+	Mn(2+) uptake NRAMP transporter MntH	NA	NA	NA	NA
WP_002913419.1\|427663_428023_-	DUF2502 domain-containing protein	NA	NA	NA	NA
WP_004174934.1\|428153_429146_-	L-glyceraldehyde 3-phosphate reductase	NA	NA	NA	NA
WP_004159719.1\|429326_430988_+	indolepyruvate decarboxylase	NA	NA	NA	NA
WP_004154521.1\|430984_432220_-	ion channel protein	NA	NA	NA	NA
WP_002913377.1\|432483_433449_+	glucokinase	NA	NA	NA	NA
WP_002913374.1\|433502_434240_-	response regulator transcription factor	A0A2R2ZGH8	Clostridioides_phage	1.5e-14	26.3
WP_032447335.1\|434251_435949_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	3.0e-47	28.7
WP_002913372.1\|436331_437546_+	alanine transaminase	NA	NA	NA	NA
WP_099119320.1\|437617_437689_-	membrane protein YpdK	NA	NA	NA	NA
WP_014907146.1\|438027_439224_-	CynX/NimT family MFS transporter	NA	NA	NA	NA
WP_009486224.1\|439220_439679_-	nucleoside deaminase	A0A0B5J096	Pandoravirus	1.6e-11	32.3
WP_002913369.1\|439811_440720_+	transcriptional regulator CynR	A0A2P0ZL89	Lactobacillus_phage	7.8e-10	24.2
WP_020801784.1\|440729_441611_-	hypothetical protein	A0A2H4JEC4	uncultured_Caudovirales_phage	1.5e-05	56.8
WP_004174945.1\|441978_442461_-	WbuC family cupin fold metalloprotein	NA	NA	NA	NA
442762:442785	attL	NA	NA	NA	NA
WP_032432293.1\|442979_444149_+\|integrase	site-specific integrase	A0A2R2Z2Y0	Escherichia_phage	9.5e-202	85.8
WP_072200997.1\|444158_444641_+	hypothetical protein	NA	NA	NA	NA
WP_077253737.1\|444705_444891_-	hypothetical protein	G3CFG7	Escherichia_phage	2.0e-13	61.1
WP_032432295.1\|444898_445564_-	DUF550 domain-containing protein	S4TSR6	Salmonella_phage	5.1e-51	66.7
WP_026055975.1\|445808_446732_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	8.4e-177	99.7
WP_077254344.1\|446877_447102_-	hypothetical protein	S4TVX5	Salmonella_phage	1.3e-14	53.8
WP_048267937.1\|447416_448277_-	DNA-binding protein	A0A2H4J902	uncultured_Caudovirales_phage	2.8e-73	53.4
WP_048333912.1\|448358_449171_-	DUF2303 family protein	NA	NA	NA	NA
WP_048997713.1\|449214_449574_-	hypothetical protein	NA	NA	NA	NA
WP_048997714.1\|449946_450204_-	hypothetical protein	NA	NA	NA	NA
WP_048997715.1\|450537_451248_-	LexA family transcriptional regulator	K7P8B2	Enterobacteria_phage	5.2e-86	67.5
WP_004104275.1\|451355_451550_+	hypothetical protein	K7PLQ6	Enterobacteria_phage	3.6e-21	79.4
WP_032420709.1\|451627_452143_+	hypothetical protein	A0A1C9II13	Salmonella_phage	3.0e-59	64.0
WP_004104272.1\|452621_452897_+	hypothetical protein	NA	NA	NA	NA
WP_048997717.1\|452889_454419_+	DEAD/DEAH box helicase	A0A286N2P9	Klebsiella_phage	5.1e-203	66.9
WP_025711392.1\|454415_455387_+	DNA primase	A0A286N2Q0	Klebsiella_phage	1.6e-109	61.1
WP_020317326.1\|455356_456001_+	bacteriophage Lambda NinG protein	A0A1W6JNX3	Morganella_phage	1.9e-39	54.3
WP_020317301.1\|455997_456642_+	SAM-binding domain protein	I6PDF5	Cronobacter_phage	2.0e-84	68.2
WP_029497192.1\|456631_457036_+	antitermination protein	S5M7R9	Escherichia_phage	5.5e-32	54.0
WP_001294159.1\|457245_457632_+	membrane protein	A0A192Y8P2	Salmonella_phage	1.6e-57	90.6
WP_000243811.1\|457618_457900_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	4.8e-19	48.4
WP_048997722.1\|457899_458529_+	glycoside hydrolase family 19 protein	F1C591	Cronobacter_phage	8.4e-88	75.4
WP_032448071.1\|458531_458807_+	hypothetical protein	G8C7W1	Escherichia_phage	6.0e-06	37.1
WP_004899656.1\|458757_458949_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	2.9e-23	94.6
WP_004216876.1\|459037_459283_+	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	3.0e-33	96.3
WP_044071291.1\|459358_459760_+	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_077260929.1\|459861_460212_+	HNH endonuclease	A0A1B5FP94	Escherichia_phage	1.2e-51	81.7
WP_001119413.1\|460371_460869_+\|terminase	phage terminase small subunit P27 family	K7PHI2	Enterobacteria_phage	7.4e-63	71.3
WP_023328632.1\|460872_462624_+\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	9.7e-251	71.6
WP_023328631.1\|462771_463998_+\|portal	phage portal protein	Q8SBI0	Shigella_phage	2.5e-208	85.3
WP_000999827.1\|463990_464590_+\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	1.0e-90	82.5
WP_048997605.1\|464599_465838_+\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	2.3e-158	69.4
WP_048997606.1\|465915_466233_+\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	1.1e-22	52.0
WP_048997607.1\|466241_466580_+\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	2.5e-38	67.9
WP_048997608.1\|466576_467026_+	HK97 gp10 family phage protein	Q9MCS9	Enterobacteria_phage	2.3e-63	83.2
WP_023302599.1\|467022_467370_+	DUF3168 domain-containing protein	K7PKL6	Enterobacterial_phage	2.8e-32	63.7
WP_048997609.1\|467426_468131_+	immunoglobulin domain-containing protein	K7PHL2	Enterobacterial_phage	1.2e-79	66.5
WP_021313622.1\|468161_468566_+\|tail	phage tail protein	K7PKV6	Enterobacterial_phage	8.5e-33	57.7
WP_004177139.1\|468568_468874_+	DUF4035 domain-containing protein	Q9MCS5	Enterobacteria_phage	4.7e-28	64.6
WP_016530182.1\|468947_469181_+	hypothetical protein	K7PH16	Enterobacteria_phage	1.9e-08	47.2
WP_031592502.1\|469241_472628_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	2.8e-302	57.6
WP_031592499.1\|472649_473123_+	hypothetical protein	A0A286S298	Klebsiella_phage	1.9e-55	62.7
WP_004864228.1\|473109_473586_+	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	4.8e-51	65.8
WP_032408661.1\|473598_473979_+	nitrite transporter	A0A286S2A6	Klebsiella_phage	5.3e-61	84.1
WP_080031128.1\|473975_477053_+	kinase	A0A286S259	Klebsiella_phage	0.0e+00	62.3
WP_047670084.1\|477923_479216_+	hypothetical protein	B5TAB2	Burkholderia_phage	2.4e-68	37.0
WP_057775242.1\|479216_479966_+	hypothetical protein	NA	NA	NA	NA
WP_032443530.1\|481120_481360_+	hypothetical protein	I6PD82	Cronobacter_phage	6.8e-22	55.7
WP_042937071.1\|481316_481688_+	hypothetical protein	K7PGV5	Enterobacterial_phage	2.4e-26	50.9
WP_004149224.1\|481894_482824_-	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	6.7e-134	81.4
481783:481806	attR	NA	NA	NA	NA
WP_002913362.1\|483113_483875_+	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_004149222.1\|483936_485265_-	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_002913359.1\|485632_485917_+	DUF406 family protein	NA	NA	NA	NA
WP_002913358.1\|486076_487387_+	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_004149220.1\|487386_489531_+	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_002913355.1\|489740_490226_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_002913348.1\|490246_490798_-	endonuclease SmrB	NA	NA	NA	NA
WP_002913346.1\|490965_491898_+	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_002913342.1\|491939_493025_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-89	46.6
WP_004174960.1\|493027_493852_+	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_002913340.1\|493851_494661_+	TSUP family transporter	NA	NA	NA	NA
WP_004174962.1\|494660_495209_+	elongation factor P hydroxylase	NA	NA	NA	NA
WP_002913338.1\|495240_495522_+	YfcL family protein	NA	NA	NA	NA
WP_020801923.1\|495583_497572_-\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_002913291.1\|497730_498951_+	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_020801925.1\|499160_500336_+	MFS transporter	NA	NA	NA	NA
WP_004174966.1\|500422_501400_-	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_002913228.1\|501510_502647_+	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	1.6e-20	27.8
WP_002913227.1\|502710_503724_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_002913226.1\|503723_504536_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA

DBSCAN-SWA_2

712402 : 719309

Planktothrix_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004180551.1\|712402_713266_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5
WP_004899467.1\|713276_714050_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-26	36.7
WP_002912636.1\|714292_715186_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
WP_004144192.1\|715431_716793_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.8e-207	94.8
WP_004175198.1\|717111_717834_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
WP_004149058.1\|717830_719309_-	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	8.5e-30	28.3

DBSCAN-SWA_3

1122821 : 1173086

Staphylococcus_phage(40.0%)

plate,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002910830.1\|1122821_1123568_+\|protease	proteasome-type protease	NA	NA	NA	NA
WP_048997745.1\|1123979_1124993_+	fatty acid desaturase	NA	NA	NA	NA
WP_004189318.1\|1124985_1125786_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_004145488.1\|1125823_1125946_-	nitrilotriacetate monooxygenase	NA	NA	NA	NA
WP_032447341.1\|1126563_1127505_+	transcriptional regulator TdcA	NA	NA	NA	NA
WP_020801826.1\|1127598_1128588_+	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA	NA	NA	NA
WP_004145486.1\|1128613_1129945_+	threonine/serine transporter TdcC	NA	NA	NA	NA
WP_020801824.1\|1129972_1131181_+	propionate kinase	NA	NA	NA	NA
WP_020801813.1\|1131209_1133504_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	3.0e-159	41.8
WP_009484368.1\|1133933_1135049_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004175489.1\|1135158_1136073_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004148804.1\|1136082_1137369_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_004200318.1\|1137365_1138241_+	ATP-binding cassette domain-containing protein	A0A285PWH2	Cedratvirus	1.5e-10	25.5
WP_004175491.1\|1138237_1138957_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-11	26.0
WP_002910720.1\|1138962_1139856_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_048997753.1\|1140139_1141783_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	5.7e-136	50.4
WP_002910717.1\|1141832_1142309_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020801827.1\|1142407_1143334_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001339197.1\|1144467_1145676_-\|transposase	IS4-like element ISVsa5 family transposase	NA	NA	NA	NA
WP_004175495.1\|1146285_1147092_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_020801945.1\|1147066_1147966_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002910657.1\|1148075_1148558_-	cold shock domain-containing protein	NA	NA	NA	NA
WP_020801940.1\|1148748_1149447_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	2.6e-05	27.2
WP_077260885.1\|1149472_1150057_-	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_002910650.1\|1150126_1150456_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_015874926.1\|1150542_1150788_+	hypothetical protein	NA	NA	NA	NA
WP_020801944.1\|1151025_1152366_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_020801943.1\|1152362_1153016_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_020801942.1\|1153019_1154717_+	OmpA family protein	NA	NA	NA	NA
WP_080031132.1\|1155175_1157662_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_080031133.1\|1160350_1161706_+	S-type Pyocin	NA	NA	NA	NA
WP_020802729.1\|1161706_1162216_+	hypothetical protein	NA	NA	NA	NA
WP_020802725.1\|1162724_1163105_+	hypothetical protein	NA	NA	NA	NA
WP_071600595.1\|1163367_1163610_+	hypothetical protein	NA	NA	NA	NA
WP_020802707.1\|1163606_1164116_+	hypothetical protein	NA	NA	NA	NA
WP_002910497.1\|1164358_1164625_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_077260886.1\|1164658_1165786_+	type VI secretion protein	NA	NA	NA	NA
WP_020802717.1\|1165769_1169180_+	intracellular multiplication/macrophage-killing	NA	NA	NA	NA
WP_004148784.1\|1169313_1171077_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_032447798.1\|1171076_1172123_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004189400.1\|1172097_1172640_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004175538.1\|1172642_1173086_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_4

1707089 : 1729710

Acidithiobacillus_phage(33.33%)

integrase,transposase

attL 1698902:1698916|attR 1726121:1726135

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1698902:1698916	attL	NA	NA	NA	NA
WP_032447479.1\|1707089_1707965_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_032447480.1\|1707948_1709499_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_020802064.1\|1709495_1711862_+	hypothetical protein	NA	NA	NA	NA
WP_020802067.1\|1711861_1712296_+	hypothetical protein	NA	NA	NA	NA
WP_020802065.1\|1712690_1712885_-	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_071596078.1\|1712868_1713201_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001189111.1\|1715082_1716591_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.6e-44	31.8
WP_032447921.1\|1718023_1718365_+	hypothetical protein	NA	NA	NA	NA
WP_032447919.1\|1718586_1720116_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	1.8e-120	45.7
WP_020802959.1\|1720126_1720870_+	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	1.0e-55	45.4
WP_032447922.1\|1721086_1722298_-	hypothetical protein	NA	NA	NA	NA
WP_085955172.1\|1724993_1726200_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.7e-100	63.2
1726121:1726135	attR	NA	NA	NA	NA
WP_155120821.1\|1726617_1726908_-	hypothetical protein	NA	NA	NA	NA
WP_000019449.1\|1726933_1727914_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	5.2e-185	98.8
WP_128933181.1\|1728560_1729710_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.8e-49	41.3

DBSCAN-SWA_5

1837623 : 1848511

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020802431.1\|1837623_1840731_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
WP_004176258.1\|1840785_1842051_+	MFS transporter	NA	NA	NA	NA
WP_001620097.1\|1842081_1843170_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_004176262.1\|1843256_1843517_-	hypothetical protein	A0A077SK33	Escherichia_phage	5.4e-41	98.8
WP_023282555.1\|1843814_1844675_+	class A extended-spectrum beta-lactamase SHV-27	A0A077SL40	Escherichia_phage	2.9e-155	99.3
WP_002210513.1\|1844695_1845457_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002903955.1\|1845718_1846621_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_048997799.1\|1846632_1847898_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	1.7e-233	99.5
WP_002210516.1\|1847890_1848511_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_6

2216107 : 2301991

Klebsiella_phage(56.1%)

integrase,holin,head,tRNA,capsid,transposase,terminase,portal,tail

attL 2253461:2253476|attR 2305678:2305693

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002901088.1\|2216107_2216608_+\|tRNA	YbaK/prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_002901080.1\|2216724_2217171_+	DUF441 domain-containing protein	NA	NA	NA	NA
WP_032447883.1\|2217154_2217946_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004148041.1\|2218047_2219232_+	CynX/NimT family MFS transporter	NA	NA	NA	NA
WP_004140471.1\|2219263_2219956_-	CTP synthase	NA	NA	NA	NA
WP_020802835.1\|2220101_2220611_+	DUF523 domain-containing protein	NA	NA	NA	NA
WP_004150779.1\|2220597_2220954_+	DUF488 domain-containing protein	NA	NA	NA	NA
WP_004176548.1\|2220943_2221183_-	DUF333 domain-containing protein	NA	NA	NA	NA
WP_004176549.1\|2221484_2222498_+	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.9e-12	29.0
WP_004150782.1\|2222555_2222657_+	YoaK family small membrane protein	NA	NA	NA	NA
WP_004213093.1\|2222656_2222731_+	protein YoaJ	NA	NA	NA	NA
WP_004140488.1\|2222848_2222974_+	hypothetical protein	NA	NA	NA	NA
WP_004140489.1\|2223033_2223297_-	DUF2534 family protein	NA	NA	NA	NA
WP_004150783.1\|2223427_2224066_-	leucine efflux protein LeuE	NA	NA	NA	NA
WP_001339197.1\|2225119_2226328_+\|transposase	IS4-like element ISVsa5 family transposase	NA	NA	NA	NA
WP_004150784.1\|2227068_2228112_-	type II asparaginase	NA	NA	NA	NA
WP_020802844.1\|2228414_2229623_+	HDIG domain-containing protein	NA	NA	NA	NA
WP_020802842.1\|2229696_2231481_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	5.8e-17	36.1
WP_004150788.1\|2231487_2232378_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004140497.1\|2232498_2234007_+	UbiD family decarboxylase	NA	NA	NA	NA
WP_004150790.1\|2234317_2235004_-	EAL domain-containing protein	NA	NA	NA	NA
WP_153244925.1\|2235453_2235642_+	hypothetical protein	NA	NA	NA	NA
WP_020802836.1\|2235620_2236253_-	DNA-binding protein	NA	NA	NA	NA
WP_004140506.1\|2236819_2237017_+	hypothetical protein	NA	NA	NA	NA
WP_004140509.1\|2237132_2238143_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_004150793.1\|2238139_2239546_-	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_004179357.1\|2239601_2240489_-	manganese catalase family protein	NA	NA	NA	NA
WP_004140514.1\|2240505_2241012_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_004148027.1\|2241038_2241533_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_004150795.1\|2241623_2241809_-	general stress protein	NA	NA	NA	NA
WP_020802850.1\|2242431_2243625_+	glutathione-dependent formaldehyde dehydrogenase	NA	NA	NA	NA
WP_004140530.1\|2243737_2243965_+	DUF1272 domain-containing protein	NA	NA	NA	NA
WP_014907803.1\|2244403_2244727_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_020802853.1\|2244719_2245112_+	hypothetical protein	NA	NA	NA	NA
WP_020802852.1\|2245108_2245822_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004892953.1\|2246094_2246247_-	isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-18	92.0
WP_057202256.1\|2246401_2247898_-\|tail	tail fiber domain-containing protein	A0A0P0IDN1	Klebsiella_phage	3.4e-127	64.2
WP_080031143.1\|2247959_2259176_-	DUF1983 domain-containing protein	Q6UAW1	Klebsiella_phage	0.0e+00	50.2
2253461:2253476	attL	NA	NA	NA	NA
WP_080031144.1\|2259238_2259850_-\|tail	tail assembly protein	Q6UAW2	Klebsiella_phage	2.6e-70	71.5
WP_021462612.1\|2259865_2260216_-	hypothetical protein	NA	NA	NA	NA
WP_017880253.1\|2260247_2260958_-	C40 family peptidase	Q6UAW4	Klebsiella_phage	8.5e-137	90.3
WP_057172004.1\|2260959_2261715_-\|tail	phage minor tail protein L	Q6UAW5	Klebsiella_phage	8.8e-124	80.1
WP_032418052.1\|2261711_2262050_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	2.2e-58	90.2
WP_057194021.1\|2262049_2265406_-\|tail	phage tail tape measure protein	Q6UAW7	Klebsiella_phage	0.0e+00	86.7
WP_014228914.1\|2265638_2266004_-\|tail	phage tail protein	Q6UAW8	Klebsiella_phage	1.6e-51	89.3
WP_014228913.1\|2266061_2266523_-\|tail	major tail shaft subunit	Q6UAX0	Klebsiella_phage	7.8e-67	83.7
WP_017898997.1\|2266554_2266956_-	hypothetical protein	Q6UAX1	Klebsiella_phage	1.7e-62	94.0
WP_032418049.1\|2266952_2267342_-	hypothetical protein	Q6UAX2	Klebsiella_phage	7.3e-58	86.0
WP_014228910.1\|2267322_2267661_-\|head,tail	head-tail adaptor protein	Q6UAX3	Klebsiella_phage	5.6e-54	91.1
WP_032418048.1\|2267657_2267975_-\|head,tail	phage gp6-like head-tail connector protein	Q6UAX4	Klebsiella_phage	5.8e-45	88.8
WP_014907814.1\|2267955_2268216_-	hypothetical protein	Q6UAX5	Klebsiella_phage	1.5e-22	63.9
WP_014228907.1\|2268274_2269561_-\|capsid	phage major capsid protein	Q6UAX6	Klebsiella_phage	4.4e-216	89.3
WP_032418047.1\|2269638_2270559_-	S49 family peptidase	Q6UAX7	Klebsiella_phage	1.6e-148	87.9
WP_057172085.1\|2270595_2271855_-\|portal	phage portal protein	Q6UAX8	Klebsiella_phage	4.7e-223	90.0
WP_032418045.1\|2271854_2272034_-	hypothetical protein	Q6UAX9	Klebsiella_phage	4.0e-11	57.6
WP_032418044.1\|2272027_2273749_-\|terminase	terminase large subunit	Q7Y413	Yersinia_phage	6.5e-191	57.4
WP_012542168.1\|2273748_2274183_-\|terminase	phage terminase small subunit P27 family	A0A1J0GV10	Halomonas_phage	9.4e-30	61.9
WP_023289184.1\|2274432_2274864_-	hypothetical protein	Q6UAS0	Klebsiella_phage	1.1e-41	62.0
WP_128972059.1\|2274860_2275133_-	hypothetical protein	NA	NA	NA	NA
WP_025861442.1\|2275129_2275492_-	HNH endonuclease	Q6UAS2	Klebsiella_phage	1.8e-58	85.8
WP_004148005.1\|2275848_2276916_+	hypothetical protein	NA	NA	NA	NA
WP_025861440.1\|2276905_2277478_-	sce7726 family protein	A0A0U2RXY7	Escherichia_phage	2.3e-55	54.3
WP_057171893.1\|2277882_2278158_-	hypothetical protein	NA	NA	NA	NA
WP_025861436.1\|2278154_2278502_-	hypothetical protein	A0A286N2Q7	Klebsiella_phage	3.7e-37	76.5
WP_032443843.1\|2278498_2279038_-	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	2.0e-98	96.1
WP_025861434.1\|2279034_2279334_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	4.5e-39	82.8
WP_004147999.1\|2280264_2280414_+	small membrane protein	NA	NA	NA	NA
WP_155120822.1\|2281151_2281355_+	hypothetical protein	NA	NA	NA	NA
WP_025861432.1\|2281598_2282201_-	hypothetical protein	H9C175	Pectobacterium_phage	1.1e-76	68.6
WP_057171894.1\|2282217_2283249_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.7e-96	49.6
WP_032418037.1\|2283448_2283841_-	DNA-binding protein	K7PHB4	Enterobacterial_phage	1.0e-11	36.6
WP_077253879.1\|2283881_2284172_-	hypothetical protein	H6WRY6	Salmonella_phage	6.1e-17	56.9
WP_032418036.1\|2284183_2284417_-	DinI family protein	K7PM44	Enterobacteria_phage	6.4e-25	69.7
WP_057171830.1\|2284942_2285638_+	hypothetical protein	NA	NA	NA	NA
WP_071957312.1\|2285649_2286303_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_080031145.1\|2286649_2287378_-	hypothetical protein	NA	NA	NA	NA
WP_057171832.1\|2287729_2288539_-	hypothetical protein	NA	NA	NA	NA
WP_057171833.1\|2288569_2289091_-	hypothetical protein	NA	NA	NA	NA
WP_057171834.1\|2289578_2290019_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_021462583.1\|2290032_2290497_-	Replication protein 14	A0A0U2JGJ0	Escherichia_phage	1.7e-61	69.5
WP_023279535.1\|2290489_2291473_-	hypothetical protein	A0A0U2RT81	Escherichia_phage	1.2e-45	55.8
WP_057171835.1\|2291524_2292079_-	hypothetical protein	NA	NA	NA	NA
WP_023342905.1\|2292081_2292294_-	helix-turn-helix transcriptional regulator	A0A077K9X2	Edwardsiella_phage	1.9e-15	57.6
WP_032428184.1\|2292399_2292780_+	helix-turn-helix domain-containing protein	A0A0M4REM4	Salmonella_phage	1.9e-10	37.7
WP_040234937.1\|2293121_2293436_-	hypothetical protein	NA	NA	NA	NA
WP_016160636.1\|2293826_2294021_+	DUF1482 family protein	NA	NA	NA	NA
WP_014228879.1\|2294063_2294408_+	transcriptional regulator	NA	NA	NA	NA
WP_057171836.1\|2294549_2296688_+	exonuclease	S4TNL0	Salmonella_phage	6.6e-100	43.0
WP_012542206.1\|2296740_2296986_+	excisionase	NA	NA	NA	NA
WP_023328117.1\|2296966_2298094_+\|integrase	tyrosine-type recombinase/integrase	O21925	Phage_21	4.4e-119	58.4
WP_004150800.1\|2298211_2299462_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.1e-19	92.6
WP_004150801.1\|2299702_2300353_+	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_004150802.1\|2300369_2300828_+	NUDIX hydrolase	NA	NA	NA	NA
WP_004150803.1\|2300884_2301991_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
2305678:2305693	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2561076 : 2570550

Brazilian_cedratvirus(16.67%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004209699.1\|2561076_2562798_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
WP_002898014.1\|2562842_2563544_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|2563897_2564116_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002896522.1\|2564246_2566526_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_002896520.1\|2566556_2566874_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|2567199_2567421_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_004150848.1\|2567497_2569438_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_004191152.1\|2569434_2570550_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7

Anti-CRISPR protein detection

Acr_ID: NZ_CP020061.1|WP_099119320.1|437617_437689_-|membrane-protein-YpdK

Click the colored protein region to show detailed information

Acr_ID: NZ_CP020061.1|WP_048997713.1|449214_449574_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NZ_CP020061.1|WP_048997714.1|449946_450204_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP020061.1|WP_099119320.1|437617_437689_-|membrane-protein-YpdK

437617_437689_-

23 aa aa

419754-504536

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP020061_3	TypeI-E	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	479100-479132	1

1. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020061 position: 479100-479132, mismatch: 1

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgacccgcagttcacccagtggccggaagag	Protospacer
*************** *****************

NZ_CP020061.1|WP_048997713.1|449214_449574_-|hypothetical-protein

449214_449574_-

119 aa aa

419754-504536

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP020061_3	TypeI-E	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	479100-479132	1

1. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020061 position: 479100-479132, mismatch: 1

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgacccgcagttcacccagtggccggaagag	Protospacer
*************** *****************

NZ_CP020061.1|WP_048997714.1|449946_450204_-|hypothetical-protein

449946_450204_-

85 aa aa

419754-504536

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP020061_3	TypeI-E	3.3\|1375154\|33\|NZ_CP020061\|PILER-CR,CRISPRCasFinder,CRT	1375154-1375186	33	479100-479132	1

1. spacer 3.3|1375154|33|NZ_CP020061|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020061 position: 479100-479132, mismatch: 1

tatgacccgcagttcccccagtggccggaagag	CRISPR spacer
tatgacccgcagttcacccagtggccggaagag	Protospacer
*************** *****************

6. NZ_CP020066

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1896 : 56677

Escherichia_phage(23.53%)

protease,transposase,integrase

attL 4629:4688|attR 65146:65965

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080031202.1\|1896_4671_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	99.3
4629:4688	attL	NA	NA	NA	NA
WP_001067855.1\|4680_5385_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_012561167.1\|5957_6323_-	hypothetical protein	NA	NA	NA	NA
WP_012561166.1\|6322_9559_-	conjugative relaxase	U5J9B0	Bacillus_phage	2.4e-05	27.3
WP_000342688.1\|9558_11088_-	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_001749975.1\|11089_11506_-	hypothetical protein	NA	NA	NA	NA
WP_020319858.1\|12278_12416_+	hypothetical protein	NA	NA	NA	NA
WP_001749973.1\|12424_13141_+	StdB	NA	NA	NA	NA
WP_000414913.1\|13142_13511_+	hypothetical protein	NA	NA	NA	NA
WP_048968061.1\|13803_14037_+	hypothetical protein	NA	NA	NA	NA
WP_001749971.1\|14147_14468_-	hypothetical protein	NA	NA	NA	NA
WP_000214483.1\|14522_14702_-	hypothetical protein	NA	NA	NA	NA
WP_000129958.1\|15428_15938_-	antirestriction protein ArdA	NA	NA	NA	NA
WP_012561126.1\|17290_17623_-	hypothetical protein	NA	NA	NA	NA
WP_001750002.1\|17831_18116_-	hypothetical protein	NA	NA	NA	NA
WP_001750003.1\|18184_18544_-	hypothetical protein	NA	NA	NA	NA
WP_000545925.1\|18540_18837_-	hypothetical protein	NA	NA	NA	NA
WP_000932975.1\|19722_19962_-	hypothetical protein	NA	NA	NA	NA
WP_000881513.1\|19971_20376_-	hypothetical protein	NA	NA	NA	NA
WP_000447669.1\|20433_20859_-	hypothetical protein	NA	NA	NA	NA
WP_000861760.1\|21273_21714_+	translesion error-prone DNA polymerase V autoproteolytic subunit MucA	A0A1W6JNS2	Morganella_phage	1.2e-27	48.8
WP_001749980.1\|21701_22967_+	translesion error-prone DNA polymerase V subunit MucB	F1C5A5	Cronobacter_phage	2.2e-119	53.8
WP_001452808.1\|23117_23909_+\|protease	zinc metalloprotease	NA	NA	NA	NA
WP_000057569.1\|23923_24265_-	hypothetical protein	NA	NA	NA	NA
WP_001749982.1\|24824_25544_+	replication initiation protein	I3WF20	Macacine_betaherpesvirus	8.6e-20	28.9
WP_001749988.1\|27500_28070_-	recombinase family protein	E5FFF9	Burkholderia_phage	5.2e-36	43.2
WP_000845048.1\|28462_29476_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_004201280.1\|29631_30105_+	trimethoprim-resistant dihydrofolate reductase DfrA14	G3MBI7	Bacillus_virus	8.4e-16	28.9
WP_001144737.1\|30325_30592_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_001389365.1\|30734_31499_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_004098817.1\|31759_32974_+	type II site-specific deoxyribonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
WP_001288432.1\|33007_34441_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	7.0e-106	50.6
WP_001749967.1\|34822_35029_-	hypothetical protein	NA	NA	NA	NA
WP_064577928.1\|35033_35522_-	restriction endonuclease	NA	NA	NA	NA
WP_001452736.1\|35730_36042_-	hypothetical protein	NA	NA	NA	NA
WP_001749965.1\|36077_36392_-	KikA protein	NA	NA	NA	NA
WP_001749964.1\|36388_36733_-	hypothetical protein	NA	NA	NA	NA
WP_024129965.1\|36748_37099_-	H-NS histone family protein	NA	NA	NA	NA
WP_001749963.1\|37162_37897_+	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_000440698.1\|37905_38187_+	hypothetical protein	NA	NA	NA	NA
WP_001749962.1\|38196_38490_+	hypothetical protein	NA	NA	NA	NA
WP_000496058.1\|38539_38857_+	hypothetical protein	NA	NA	NA	NA
WP_001749961.1\|38856_41457_+	VirB4 family type IV secretion/conjugal transfer ATPase	NA	NA	NA	NA
WP_001749960.1\|41474_42188_+	hypothetical protein	NA	NA	NA	NA
WP_001749959.1\|42195_42423_+	IncN-type entry exclusion lipoprotein EexN	NA	NA	NA	NA
WP_001749958.1\|42438_43479_+	type IV secretion system protein	NA	NA	NA	NA
WP_000646594.1\|43697_44396_+	type IV secretion system protein	NA	NA	NA	NA
WP_019706045.1\|44469_45291_+	conjugal transfer protein TraO	NA	NA	NA	NA
WP_000101710.1\|45290_46451_+	TrbI/VirB10 family protein	NA	NA	NA	NA
WP_000128596.1\|46492_47488_+	conjugal transfer protein TraG	NA	NA	NA	NA
WP_000792636.1\|47487_48021_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.8e-21	33.9
WP_004152397.1\|52038_53358_+\|transposase	IS1182-like element ISKpn6 family transposase	Q9MBP7	Staphylococcus_prophage	1.9e-12	24.2
WP_004152396.1\|53607_54489_-	carbapenem-hydrolyzing class A beta-lactamase KPC-3	A0A1B0VBP7	Salmonella_phage	2.8e-73	52.2
WP_004152394.1\|54875_55655_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
WP_004199214.1\|55651_56677_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
65146:65965	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage