CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NZ_CP016701	Lactococcus lactis subsp. lactis strain 275 plasmid p275C, complete sequence	0 crisprs	NA	0
NZ_CP016699	Lactococcus lactis subsp. lactis strain 275 plasmid p275A, complete sequence	0 crisprs	NA	1
NZ_CP015897	Lactococcus lactis subsp. lactis strain 275 chromosome, complete genome	1 crisprs	cas3,DEDDh,cas4,csa3,DinG	13
NZ_CP016702	Lactococcus lactis subsp. lactis strain 275 plasmid p275D, complete sequence	0 crisprs	NA	0
NZ_CP016700	Lactococcus lactis subsp. lactis strain 275 plasmid p275B, complete sequence	0 crisprs	NA	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1697 : 61398

Streptococcus_phage(34.78%)

transposase,bacteriocin,integrase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081144385.1\|1697_2588_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_014573541.1\|2872_3106_+	hypothetical protein	NA	NA	NA	NA
WP_023349312.1\|3115_3874_+	AAA family ATPase	H7BUL8	unidentified_phage	7.2e-17	28.8
WP_014573539.1\|3877_4606_+	ParB N-terminal domain-containing protein	Q4ZC37	Staphylococcus_virus	7.2e-06	27.7
WP_014011586.1\|4635_4986_-	hypothetical protein	A0A182BQ76	Lactococcus_phage	2.3e-10	75.6
WP_081144386.1\|4975_6442_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.4e-122	51.1
WP_153040032.1\|7815_8497_-\|transposase	IS6 family transposase	A0A1X9I6E7	Streptococcus_phage	5.5e-109	83.2
WP_014570881.1\|9475_9676_+	hypothetical protein	NA	NA	NA	NA
WP_003132324.1\|9806_10007_+	cold shock domain-containing protein	A0A1X9IGI9	Lactococcus_phage	1.6e-13	54.7
WP_012898583.1\|10286_10487_+	cold-shock protein	Q9AZD3	Lactococcus_phage	6.9e-28	92.4
WP_003131011.1\|11001_11241_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_003131013.1\|11270_11831_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_015425997.1\|11840_12029_+	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_015425998.1\|12049_12601_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_081144389.1\|14030_14573_-\|integrase	site-specific integrase	D2XR58	Bacillus_phage	3.8e-20	37.9
WP_081144390.1\|14601_14898_-	DUF4298 domain-containing protein	NA	NA	NA	NA
WP_153040033.1\|16216_17328_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.7e-49	41.1
WP_081144391.1\|17474_18362_+	EamA family transporter	NA	NA	NA	NA
WP_081144392.1\|20033_20789_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_010383508.1\|20785_21436_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.7e-22	31.5
WP_081144393.1\|21791_22433_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.8e-98	82.2
WP_031297153.1\|22652_22883_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_011669076.1\|22892_23255_+	hypothetical protein	NA	NA	NA	NA
WP_023349276.1\|23441_23711_+	hypothetical protein	NA	NA	NA	NA
WP_080671893.1\|23855_24431_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_153915025.1\|24504_24669_+	hypothetical protein	NA	NA	NA	NA
WP_023349278.1\|24695_25319_+	cysteine hydrolase	NA	NA	NA	NA
WP_081144394.1\|25456_26806_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.4e-116	51.1
WP_081144396.1\|29757_30378_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.2e-99	84.4
WP_081144397.1\|30781_31786_+	galactose mutarotase	NA	NA	NA	NA
WP_081144398.1\|31824_36834_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_012477748.1\|39522_40419_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_012477749.1\|40415_41279_-	AbiEi	NA	NA	NA	NA
WP_081144401.1\|41631_42213_-	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	2.5e-33	44.7
WP_023349284.1\|42484_43321_-	AraC family transcriptional regulator	D0R0F8	Streptococcus_phage	4.1e-74	50.5
WP_011915238.1\|43608_43944_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_021166316.1\|44434_44800_-	hypothetical protein	NA	NA	NA	NA
WP_161487267.1\|45103_45271_-	hypothetical protein	NA	NA	NA	NA
WP_081144402.1\|45372_46422_-	DUF389 domain-containing protein	NA	NA	NA	NA
WP_153040034.1\|46892_47574_-\|transposase	IS6 family transposase	A0A1X9I6E7	Streptococcus_phage	1.3e-110	84.1
WP_010890674.1\|47685_47988_-	hypothetical protein	NA	NA	NA	NA
WP_081144403.1\|47980_48256_-	DUF2089 family protein	NA	NA	NA	NA
WP_080715440.1\|48485_48830_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_011834702.1\|48826_49654_+	hypothetical protein	NA	NA	NA	NA
WP_040087662.1\|49729_50503_+	hypothetical protein	NA	NA	NA	NA
WP_010276787.1\|50633_50873_+	hypothetical protein	NA	NA	NA	NA
WP_010383508.1\|50869_51520_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.7e-22	31.5
WP_081144392.1\|51516_52272_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_081144404.1\|52425_53106_+\|transposase	IS6-like element ISS1S family transposase	A0A1X9I6C6	Streptococcus_phage	5.0e-110	84.5
WP_003108064.1\|53474_53897_-	cupin domain-containing protein	Q2I8C5	Bacillus_phage	3.1e-38	61.0
WP_081144405.1\|54112_55099_+\|transposase	IS30-like element IS6770 family transposase	W5R8L2	Staphylococcus_phage	6.2e-37	36.4
WP_047686044.1\|55266_55476_+	hypothetical protein	NA	NA	NA	NA
WP_032398590.1\|55648_55933_-	hypothetical protein	NA	NA	NA	NA
WP_032398591.1\|55937_56690_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_095348744.1\|56686_57409_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_081144406.1\|57405_58161_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.1e-44	38.7
WP_047686051.1\|58310_59015_+	response regulator transcription factor	W8CYM9	Bacillus_phage	9.3e-35	37.3
WP_081144407.1\|59016_60414_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_010890648.1\|60717_61398_-\|transposase	IS6-like element ISS1S family transposase	A0A1X9I6C6	Streptococcus_phage	8.5e-110	84.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP015897

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015897_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015897_1

1954081-1954175

Orphan

Consensus_repeat	Method
TTTATTACTGACAGACTTGTCAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015897_1

>merge|NZ_CP015897|1|1954081-1954175|CRISPRCasFinder
TTTATTACTGACAGACTTGTCAGCTTTGCTGACAAATCCTTCATCCATTGATAAAAAGCTCAATTCAATCGCTTTTTACTGACAGACTTGTCAGC

>NZ_CP015897|1|1|1954081-1954175|CRISPRCasFinder
TTTATTACTGACAGACTTGTCAGC	TTTGCTGACAAATCCTTCATCCATTGATAAAAAGCTCAATTCAATCG
CTTTTTACTGACAGACTTGTCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015897.1\|WP_004255171.1\|1961072_1961807_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP015897.1\|WP_081144356.1\|1947886_1948282_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015897.1\|WP_004255184.1\|1956568_1957825_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP015897.1\|WP_004255173.1\|1960241_1960943_-\|adaptor-protein-MecA	unknown	unknown	gnl\|CDD\|227199
NZ_CP015897.1\|WP_063283786.1\|1947669_1947879_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP015897.1\|WP_063283784.1\|1948593_1948854_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015897.1\|WP_063283783.1\|1949763_1950330_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015897.1\|WP_004255194.1\|1954867_1955350_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP015897.1\|WP_004255189.1\|1955351_1956569_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP015897.1\|WP_063283782.1\|1950348_1951182_+\|DUF4428-domain-containing-protein	unknown	unknown	gnl\|CDD\|373083
NZ_CP015897.1\|WP_004255177.1\|1958907_1960239_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
NZ_CP015897.1\|WP_063283793.1\|1949387_1949735_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP015897.1\|WP_004255158.1\|1961806_1962493_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP015897.1\|WP_011676017.1\|1948867_1949098_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015897.1\|WP_003130548.1\|1962640_1963549_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_CP015897.1\|WP_004255207.1\|1952647_1954060_-\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NZ_CP015897.1\|WP_004255197.1\|1954293_1954752_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NZ_CP015897.1\|WP_063283785.1\|1948330_1948585_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015897.1\|WP_081144357.1\|1951304_1952444_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP015897.1\|WP_004255181.1\|1957962_1958733_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473

Protein	Function_ID	Function_description	E-value
NZ_CP015897.1\|WP_004255171.1\|1961072_1961807_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.02808e-157
NZ_CP015897.1\|WP_004255189.1\|1955351_1956569_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP015897.1\|WP_004255184.1\|1956568_1957825_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	7.76673e-131
NZ_CP015897.1\|WP_004255173.1\|1960241_1960943_-\|adaptor-protein-MecA	gnl\|CDD\|227199	COG4862, MecA, Negative regulator of genetic competence, sporulation and motility [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion].	3.81196e-86
NZ_CP015897.1\|WP_063283786.1\|1947669_1947879_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	4.41795e-14
NZ_CP015897.1\|WP_004255194.1\|1954867_1955350_-\|hypothetical-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	5.11388e-22
NZ_CP015897.1\|WP_063283782.1\|1950348_1951182_+\|DUF4428-domain-containing-protein	gnl\|CDD\|373083	pfam14471, DUF4428, Domain of unknown function (DUF4428). This putative zinc finger domain is found in uncharacterized bacterial proteins.	2.82132e-08
NZ_CP015897.1\|WP_004255177.1\|1958907_1960239_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	5.23235e-85
NZ_CP015897.1\|WP_063283793.1\|1949387_1949735_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.38386e-05
NZ_CP015897.1\|WP_004255158.1\|1961806_1962493_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.09368e-76
NZ_CP015897.1\|WP_003130548.1\|1962640_1963549_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	2.39571e-70
NZ_CP015897.1\|WP_004255207.1\|1952647_1954060_-\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP015897.1\|WP_004255197.1\|1954293_1954752_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	9.34852e-67
NZ_CP015897.1\|WP_081144357.1\|1951304_1952444_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	8.26126e-35
NZ_CP015897.1\|WP_004255181.1\|1957962_1958733_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	2.57723e-148

>NZ_CP015897.1|WP_004255207.1|1952647_1954060_-|Fe-S-cluster-assembly-protein-SufB
MTENSTQEVVKDLEEYKFGFHDNAELEFTTGLGLTEEVIREISETKNEPEWMLEFRLKSFEAFKKLDMPKWGPDLSGIDFNDIVYYQKPSAKAARSWEDVPQEIKDTFEKIGIPEAERSYLAGASAQYESEVVYHNMKDEFEKLGIIFTDTDSGLRDYPEIFKKYFSKLVPPTDNKLAALNSAVWSGGSFVYVPKGVKCEIPIQAYFRINNEKSGQFERTLIIVEEGASIQYVEGCTAPTYSASSLHAAVVEIFVEEGGYMRYSTIQNWSDNVYNLVTKRAAAEKNATVEWIDGNLGSKVSMKYPAVHLNGPGARGTMLSIAFAGANQNQDTGAKMIHNAPNTSSSIISKSIAKNGGAVNYRGQVTFGKNSKKSASHIECDTILMDDLSKSDTVPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLTEKEATDMIVMGFIEPFTKELPMEYAVELNRLISYSMEGSIG
>NZ_CP015897.1|WP_081144357.1|1951304_1952444_+|site-specific-integrase
MWIEDLPNGKYKYFERYRDPLTEKLKKVSVTLDKKTPRAQKIALKELTEKINKILSHNEGSDITFVDLYDEYYKNWSPTVKASSLRGTTANDNRILEKIGKNAKARNVNRRLIQDLVNEMMDEGYAYSYYNGFKKRFHSILDFGVRMGYLEVNEASFVKAPKKTKTFNEVQEKRDSYLELSDIKKILSVLRITSRVEHIANFVEFMAYTGARYGETAALTIDEIDLENGTVKINGTYDRALKIKTTPKTEFSYRTITISENIKNIIQEQLELLELHRSLKGNDFNKDNYIFFTVNGAAIDLDTLNVIVRRAAEKVGITKHITSHIFRHSHIALLAELGIPLSAAMDRVGHTDYKTTLNIYSHVTKSVKIDIVKKLNEIK
>NZ_CP015897.1|WP_063283782.1|1950348_1951182_+|DUF4428-domain-containing-protein
MKNKECPICNKKLTMMTARIKLKKDDITVCKDCLIKAGYGTGIKDIDNISKMVTLNDISEKLKSRDVNSVSKSSSLELEQNADPSLLLKLSKSYVKNFESTLQIPDYIKYNDKTGELLLKNGPLTSWRKSNIRNVKNYEVIQNGKNLQGFGLGRAAAGALLTGGIGLLIGFTKKKEVVTELRLHIKLNSIDNPAFDIKFISTKTKTDSFTYRSSIKTLEQITNFLDAALSEQSSEINMVVNNSTPSVADELKKFKDLLDLGAINEDEYNTQKEKLLK
>NZ_CP015897.1|WP_063283783.1|1949763_1950330_+|hypothetical-protein
MTGKELLEIIIIKIENLGIELKYEKLSGASAYISYKYGWGIIDIERATAFEICHEYIHAKNKDLIRHSEYDWDNPCEKIADKESILLLWDIFERNDGTVEDINRFIEITGSPEKLTKIIVLKSKIKSWDKEEVQYQVTHYLDSTDDEPESWNVYSIMDACHIDHKWESLVMSTLLDISSKIGLQQQII
>NZ_CP015897.1|WP_063283793.1|1949387_1949735_+|XRE-family-transcriptional-regulator
MTTFDRIKKLAEKRGKSLPAVSADLEFSDNLFYRWKTSNPKASDLAKVADYFHVSVDYLLGRDTTEPKNQTVDLADLANKPKDFDWDSVLSVGGKPIPEEDKEIIRRLFAHKLSD
>NZ_CP015897.1|WP_011676017.1|1948867_1949098_-|hypothetical-protein
MSEVEQSFDSQRKKIVEYLEQEGKGNKDVIWAYENIKEPPYKFRKSDISSVLNGNRKYTQSVKWLITFLIKYFDLD
>NZ_CP015897.1|WP_063283784.1|1948593_1948854_-|hypothetical-protein
MPYAKITYLPVENAEDAEWCDKKHLMQKWEGLTKGTLTAWLTEMRDRPEFKKGVLNPTHGLVFINKEIFKEFVEWKEATRYKSYKK
>NZ_CP015897.1|WP_063283785.1|1948330_1948585_-|hypothetical-protein
MLKIKLLNKSDQQWLEGRKDVEEQLEIYSSILNANDRVRAMKQPRAQPSESLVHYAKEQSLGMWLEKSPFFAEMKKARTGNASW
>NZ_CP015897.1|WP_081144356.1|1947886_1948282_-|hypothetical-protein
MKSNVKFDFTKIKKRTVGARNMILTPTIHISKGGDLSFYCINVADTPYFRVAKTGNLIGQEFSNSQFSNSFTSRERGSAFCAVARSVIKEIEFEKYIGTDYHSANFALQKESENLYWFDLTSTVTKYKKLK
>NZ_CP015897.1|WP_063283786.1|1947669_1947879_-|helix-turn-helix-transcriptional-regulator
MIKNKLFYWMDKQKVSISEISKDTGLSRTTLTDLKFHRTARIDLRTLESLCQYFNITPGDFFEYKPKEK
>NZ_CP015897.1|WP_004255197.1|1954293_1954752_-|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MALSKLDNLYRAVILDHSSNPRHAGELQTGCMVDLNNPTCGDVIRLTVEFENDVISNIAFSGHGCTISTASASMMTVAVLGKTKEEAKELATIFSAMVTGETDERQEKLGDAQFLAGVSKFPARVKCSTLAWNALKKAIDVGEAQETVIHGE
>NZ_CP015897.1|WP_004255194.1|1954867_1955350_-|hypothetical-protein
MLNWVASLPLWLATTFLFVVVFFRAQCTFWLGKLSYHGILKTKWGKKLEKNSETSAGILAIQKMGWPIIPLSFLTVGFQTAVQFGAGLTNWSWYKYTLAAIPGYLAWGFIYASGGLSLFRSLVQGSIGLLILFIIIILAVVIAANLILRYIRKNGIKTDD
>NZ_CP015897.1|WP_004255189.1|1955351_1956569_-|cysteine-desulfurase
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRQFINAKSTKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKDGQLDMDDLRKKITNQTKFVSIAHVSNVLGTINPVEEITKIAHEHGAYMAVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQFEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEIELIDYLMPKLQEIEGLKIYGPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKEFFNLD
>NZ_CP015897.1|WP_004255184.1|1956568_1957825_-|Fe-S-cluster-assembly-protein-SufD
MNQEILNFSQMHAEPAWLSDLRQKAALEFENLELPNIERVKINRWGLDHLSISENEEIGSVPTFTEIPNHPLLVQVGSQTVMEQMTPNLAEQGVIFTDFNSALTEIPELLEENFGSVVPFNESRLTAANTVTFNSGLVLYVPDGVEVLEPIESILMQEGSSEVPFNKRILIIVGKNAKVDYLERLETSDEQSSKAKANIVVEVIAKAGAQVKFAAIDRLGENVTASVVRRGLIGDNATVDWSVGVMNDGNVVADFDSDLKGNGSHSQIKVIGISTGHQTQGIDTRVTNFGLNSVGHILQNGVILDKGTLTFNAIGHIIKGAKNADAQQSSHVLMLSDKGRGDANPILLIDENEVTAGHAASVGQVDEEDLFYLQSRGLDEETAKRLVIRGFLGSVVSEIPVKSVQAEFIETIERKLGM
>NZ_CP015897.1|WP_004255181.1|1957962_1958733_-|Fe-S-cluster-assembly-ATPase-SufC
MATLEIKNLHVAIEDKEILKGVNLVINTNEIHAIMGPNGTGKSTLSAAIMGNPNYSVTQGEVLFDGQNVLEMSVDERARLGLFLAMQYPSEIPGITNAEFLRAAMNAKRAEDDKVSVMEFIKKLDKNMEVLSMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPTFAILDEIDSGLDIDALKVVAKGVNSMRGEKFGALIITHYQRLLDYITPDVVHIMMDGRVVKTGGAELAKRLETEGYVNIAEELGLEYKEEV
>NZ_CP015897.1|WP_004255177.1|1958907_1960239_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MVDTLKEIPFALKFLIVIIITFGISVILTPIMTFVSKAIGAVDKPNERRVNKKPMPSAGGLVIFIAFAIATLFILPHIVHNQPPIHSQPPVHGASHQPIQLVSYFSYIWPFIVGAGIVVLTGLIDDIKEISPKMKLLGLTVAASFIWFFTNARFDNLKIPFGGPLLIFPAWLSFIFTVFWILAITNAINLIDGLDGLASGVSIISLTTMGIVSYFFLPSPNVFLPITIFIMVAAIMGFFPYNYHPAIIYLGDTGALFLGFIISVASLQGLKNATAVAVLTPLLILGVPITDTIMAMVRRKLNRQSIATADKRHLHHRLMALGFTHHGAVLVIYGIASIFAFISILLQFSSRIGGILLVIACLFGLEIFIELVGILGENRQPVLKALKFVGNSSYRDKVLHSDEDADIDENEEDIGNHSMIDEEIDEPTQEFPIQNYRRSRNKK
>NZ_CP015897.1|WP_004255173.1|1960241_1960943_-|adaptor-protein-MecA
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAMLGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKNVKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI
>NZ_CP015897.1|WP_004255171.1|1961072_1961807_-|amino-acid-ABC-transporter-ATP-binding-protein
MNEYLIEIKNLHKYFGKNEVLKGLDIQIKKGEVVVMIGPSGSGKSTFLRTMNLLEKPTDGQVYFEGVNIADKSVDVFKHREKMGMVFQQFNLFPNMTVLENLCLAPVKTGKMTKEEAKKTAEDLLQRVGLSDKAEAYPQALSGGQQQRVAIARALAMNPDVMLFDEPTSALDPEMVGEVLAVMQELAKEGMTMVVVTHEMGFAKTVADRVLFMADGTIVEQGKPAQVFDSPKEKRTQDFLAKVL
>NZ_CP015897.1|WP_004255158.1|1961806_1962493_-|amino-acid-ABC-transporter-permease
MNFDFLPKYLPYFNDGMIVTILISAFVVLIGTLLGIVTALAKISKIAPLRWLANIYIEIFRGTPMLVQIMLGFGLMGSLSLPTFQVGILQQDLGRLIPGIIVISLNSGAYMAEIVRAGIEAVPLGQKEAAYSLGIRPRQAMATVILPQALRNILPAVGNEFVTIIKDSSLLYTIGVMEVFNGAQTVANLTYQTISPMLFVALYYFVVTFVVSRLLVLFEKKLGKGYAK
>NZ_CP015897.1|WP_003130548.1|1962640_1963549_-|diacylglycerol-kinase-family-lipid-kinase
MTYYLLANPNSGAGKGARTLETLIPYLEKNNYEYRLFKTKAAGEEGALVRQILDLKNPDDHLVIIGGDGTISLVINELPEEEAFSYIPSGSGNDFARSLKLKLDPIESFEAARRGINHEIFIMNYQSKGLSGYALNNIGIGLDATIVKSANEGKLKQVLNKLKLGSFSYILTALHVLITKKPFPALIEVENQEISLENAFLMTFTKHPYFGGGVKISPEATNENADIHLVEYNKHHLLRTFSLIPSVLRGMHLKHPLFLHRVSPQFSVELAESQPVQIDGEIHELVAADRLSISTERRMIIY

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

35148 : 45074

Lactococcus_phage(92.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046781182.1\|35148_35472_-	sigma-70 family RNA polymerase sigma factor	Q9AZI1	Lactococcus_phage	2.5e-43	82.2
WP_042748295.1\|35577_35910_-	hypothetical protein	Q9AZE0	Lactococcus_phage	5.0e-39	75.7
WP_042748294.1\|36055_36358_-	hypothetical protein	NA	NA	NA	NA
WP_003132187.1\|36701_37325_+	HAD family phosphatase	NA	NA	NA	NA
WP_081144148.1\|37371_37953_-	hypothetical protein	Q9AZI4	Lactococcus_phage	6.4e-66	67.9
WP_081144150.1\|38170_39805_-	DNA primase	Q9AZI5	Lactococcus_phage	4.0e-307	95.6
WP_010905046.1\|39815_40610_-	hypothetical protein	Q9AZI6	Lactococcus_phage	5.4e-156	100.0
WP_010905047.1\|40613_40943_-	hypothetical protein	Q9AZI7	Lactococcus_phage	5.2e-57	100.0
WP_010905048.1\|40929_41124_-	hypothetical protein	Q9AZI8	Lactococcus_phage	2.3e-28	100.0
WP_031559293.1\|41371_41611_-	hypothetical protein	Q9AZF0	Lactococcus_phage	1.7e-36	94.9
WP_031559294.1\|41653_41932_-	hypothetical protein	Q9AZJ1	Lactococcus_phage	1.5e-33	74.2
WP_014573407.1\|41928_42147_-	hypothetical protein	NA	NA	NA	NA
WP_081144152.1\|42143_42665_-	hypothetical protein	Q9AZJ3	Lactococcus_phage	6.8e-75	80.9
WP_063283709.1\|42668_42863_-	DUF1655 domain-containing protein	Q9AZF2	Lactococcus_phage	8.7e-28	96.9
WP_046781193.1\|42933_43659_-	hypothetical protein	R9QNB1	Lactococcus_phage	8.9e-65	61.4
WP_014735153.1\|43830_44052_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011835948.1\|44222_44765_+	helix-turn-helix transcriptional regulator	A0A0P0IV68	Lactobacillus_phage	3.3e-08	50.8
WP_031559300.1\|44879_45074_+	hypothetical protein	Q9AZK1	Lactococcus_phage	4.3e-27	95.3

DBSCAN-SWA_2

424853 : 436984

Streptococcus_phage(40.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003131595.1\|424853_425171_+	thioredoxin family protein	A0A0K2FIM3	Achromobacter_phage	4.5e-05	30.4
WP_003131594.1\|425256_425883_+\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_014570381.1\|426045_427386_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_010905314.1\|427475_427865_+	single-stranded DNA-binding protein	A0A0K0MWE1	Streptococcus_phage	1.4e-24	45.0
WP_003131589.1\|427984_428269_+	co-chaperone GroES	A0A221S386	uncultured_virus	3.1e-13	44.1
WP_003131585.1\|428356_429985_+	chaperonin GroEL	A0A219YK78	uncultured_virus	4.9e-156	56.8
WP_003131583.1\|430030_430843_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	3.1e-34	38.1
WP_014570382.1\|431013_432456_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	1.4e-32	33.0
WP_003131580.1\|432448_433150_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.2e-42	39.7
WP_003131575.1\|433327_433963_+	dTMP kinase	M1PSC7	Streptococcus_phage	5.4e-74	65.0
WP_003131573.1\|434095_434956_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	5.0e-67	45.2
WP_003131572.1\|435007_435790_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_003131570.1\|435782_436109_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_003131568.1\|436108_436984_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	8.7e-99	65.4

DBSCAN-SWA_3

474028 : 506776

Lactococcus_phage(100.0%)

head,tail,protease,portal,tRNA,capsid,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003131526.1\|474028_474475_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_003131525.1\|474471_474990_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003131524.1\|475094_476480_+	LCP family protein	NA	NA	NA	NA
WP_081144184.1\|477897_478758_-	helix-turn-helix domain-containing protein	A0A1B1IMU5	Lactococcus_phage	4.7e-158	98.3
WP_081144186.1\|479158_479299_-	rubredoxin-like protein	NA	NA	NA	NA
WP_081144188.1\|479521_479884_-	hypothetical protein	NA	NA	NA	NA
WP_081144190.1\|479921_480131_+	hypothetical protein	NA	NA	NA	NA
WP_015966797.1\|480155_480386_+	cro2009	Q77NT7	Lactococcus_phage	6.7e-35	100.0
WP_011834773.1\|480397_480616_+	hypothetical protein	A0A059NT62	Lactococcus_phage	8.6e-32	100.0
WP_081144192.1\|480625_481339_+	phage antirepressor Ant	A0A059NT90	Lactococcus_phage	5.9e-130	99.6
WP_081144194.1\|481351_481684_+	DUF771 domain-containing protein	Q9AZQ3	Lactococcus_phage	3.2e-54	96.3
WP_032399005.1\|481821_482046_+	hypothetical protein	Q38333	Lactococcus_phage	3.0e-32	95.9
WP_081144195.1\|482042_482237_+	hypothetical protein	A0A1P8BKS3	Lactococcus_phage	3.3e-27	96.9
WP_032399006.1\|482246_482489_+	hypothetical protein	Q38336	Lactococcus_phage	1.6e-34	91.2
WP_003132838.1\|482590_482986_+	hypothetical protein	A0A1P8BL23	Lactococcus_phage	3.6e-68	98.5
WP_081144196.1\|482994_483753_+	hypothetical protein	Q0ILF6	Lactococcus_phage	9.7e-147	99.6
WP_015967987.1\|483745_484171_+	single-stranded DNA-binding protein	Q9MC32	Lactococcus_phage	1.2e-74	100.0
WP_023189114.1\|484295_485078_+	phage replisome organiser protein	A0A1P8BKN4	Lactococcus_phage	3.7e-125	95.8
WP_081144197.1\|485077_485803_+	hypothetical protein	Q9MC31	Lactococcus_phage	9.0e-134	99.6
WP_081144198.1\|485799_486189_+	RusA family crossover junction endodeoxyribonuclease	R9QLL1	Lactococcus_phage	1.7e-67	97.7
WP_081144199.1\|486191_486434_+	DUF1031 family protein	A0A1P8BLU5	Lactococcus_phage	2.6e-37	96.2
WP_081144201.1\|486686_487256_+	DUF658 family protein	Q38104	Lactococcus_phage	7.6e-88	95.2
WP_010905356.1\|487449_487656_+	DUF1125 domain-containing protein	Q9MC26	Lactococcus_phage	2.6e-30	100.0
WP_081144202.1\|487648_488341_+	DUF1642 domain-containing protein	A0A1P8BKG5	Lactococcus_phage	6.4e-81	72.0
WP_081144203.1\|488337_488757_+	dUTP diphosphatase	Q9MBX9	Lactococcus_phage	1.5e-72	99.3
WP_098407775.1\|489050_489290_+	hypothetical protein	A0A1P8BL80	Lactococcus_phage	7.7e-18	62.8
WP_081144204.1\|489286_489967_+	hypothetical protein	Q8LTS1	Lactococcus_phage	3.2e-125	96.9
WP_015967997.1\|490013_490232_+	hypothetical protein	Q8LTS0	Lactococcus_phage	2.9e-35	100.0
WP_081144205.1\|490228_490429_+	DUF1660 domain-containing protein	A0A1P8BL58	Lactococcus_phage	1.3e-34	97.0
WP_015967999.1\|490609_490792_+	hypothetical protein	Q8LTR8	Lactococcus_phage	2.4e-27	100.0
WP_015968000.1\|490788_490968_+	hypothetical protein	Q8LTR7	Lactococcus_phage	6.2e-20	100.0
WP_015968001.1\|491105_491570_+	hypothetical protein	Q8LTR6	Lactococcus_phage	2.5e-81	100.0
WP_014573151.1\|491817_492240_+	DUF722 domain-containing protein	Q9AYX5	Lactococcus_phage	5.5e-75	100.0
WP_025017211.1\|492466_492673_+	helix-turn-helix transcriptional regulator	A0A059NT51	Lactococcus_phage	2.1e-08	43.1
WP_081144207.1\|492685_493189_+	HNH endonuclease	Q9AZM8	Lactococcus_phage	7.0e-93	99.4
WP_047687184.1\|493348_493744_+\|terminase	phage terminase small subunit P27 family	Q9AZM7	Lactococcus_phage	1.4e-19	39.3
WP_081144208.1\|493743_495558_+\|terminase	terminase large subunit	Q9AZM6	Lactococcus_phage	0.0e+00	98.8
WP_023164518.1\|495727_496807_+\|portal	phage portal protein	Q9AZM4	Lactococcus_phage	1.2e-198	99.7
WP_010905378.1\|496806_497394_+\|head,protease	HK97 family phage prohead protease	Q9AZM3	Lactococcus_phage	4.4e-107	100.0
WP_081144209.1\|497383_498697_+\|capsid	phage major capsid protein	Q9AZM2	Lactococcus_phage	2.7e-189	95.7
WP_081144210.1\|498707_499013_+	hypothetical protein	Q9AZM1	Lactococcus_phage	4.1e-48	96.0
WP_081144211.1\|498999_499335_+\|head	phage head closure protein	Q9AZM0	Lactococcus_phage	1.7e-55	99.1
WP_081144212.1\|499331_499817_+	HK97 gp10 family phage protein	Q9AZL9	Lactococcus_phage	1.4e-77	93.2
WP_010905383.1\|499813_500209_+	DUF806 family protein	Q9AZL8	Lactococcus_phage	1.4e-67	100.0
WP_081144213.1\|500210_500816_+	hypothetical protein	Q9AZL7	Lactococcus_phage	2.4e-108	99.5
WP_081144214.1\|500875_501220_+	hypothetical protein	Q9AZL6	Lactococcus_phage	1.6e-27	98.2
WP_021166226.1\|501237_501408_+	hypothetical protein	NA	NA	NA	NA
WP_081144215.1\|501389_505229_+	tape measure protein	Q9AZL5	Lactococcus_phage	0.0e+00	93.0
WP_081144216.1\|505231_506776_+\|tail	phage tail protein	Q9AZR9	Lactococcus_phage	4.9e-230	79.4

DBSCAN-SWA_4

510282 : 513665

Lactococcus_phage(83.33%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081144374.1\|510282_511743_+	collagen-like protein	A0A1B1IN44	Lactococcus_phage	8.4e-123	58.0
WP_081144217.1\|511754_511991_+	hypothetical protein	A0A1B1IM34	Lactococcus_phage	7.9e-31	91.0
WP_014570798.1\|512003_512354_+	hypothetical protein	A5GYT0	Lactococcus_phage	1.8e-55	100.0
WP_010905918.1\|512366_512666_+\|holin	phage holin	Q9AZR2	Lactococcus_phage	1.3e-46	100.0
WP_081144218.1\|512667_512886_+	hypothetical protein	A0A0K2CZA1	Paenibacillus_phage	8.9e-13	58.1
WP_081144219.1\|512885_513665_+\|holin	phage holin	Q9AZR1	Lactococcus_phage	6.7e-127	98.8

DBSCAN-SWA_5

630267 : 684209

Bacillus_phage(33.33%)

tRNA,protease,integrase,transposase

attL 649590:649649|attR 663025:663137

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003129541.1\|630267_631152_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003129542.1\|631234_631903_+	hypothetical protein	NA	NA	NA	NA
WP_003129543.1\|632072_632969_+	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	1.8e-35	34.8
WP_003129544.1\|633343_633604_+	membrane protein	NA	NA	NA	NA
WP_003129545.1\|633961_634885_+	ribonuclease Z	NA	NA	NA	NA
WP_003129546.1\|634877_635579_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_003129547.1\|635745_637974_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.3e-79	30.4
WP_012897343.1\|638096_638609_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	9.1e-32	44.0
WP_003129551.1\|638824_639388_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_014570395.1\|639524_641177_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_025016857.1\|641236_641710_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_120784970.1\|643050_644423_-\|transposase	IS3-like element ISLla3 family transposase	A0A1B1P773	Bacillus_phage	3.0e-53	43.1
WP_010905471.1\|644622_645078_+	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_014570398.1\|645067_647518_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	2.2e-123	33.9
WP_003129564.1\|647652_648210_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_010905473.1\|648394_649696_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.0e-217	87.6
649590:649649	attL	NA	NA	NA	NA
WP_032951316.1\|649784_650720_+\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	8.0e-26	28.1
WP_011675617.1\|652199_652376_+	hypothetical protein	NA	NA	NA	NA
WP_063302290.1\|652413_653700_+	hypothetical protein	NA	NA	NA	NA
WP_003138385.1\|654572_655748_-\|transposase	IS256-like element IS905 family transposase	A0A0N9STL0	Staphylococcus_phage	2.5e-32	32.3
WP_063302274.1\|656108_657713_+	AAA family ATPase	NA	NA	NA	NA
WP_063302275.1\|657697_658813_+	AAA family ATPase	NA	NA	NA	NA
WP_088792927.1\|659058_660170_-\|transposase	IS3-like element IS981 family transposase	A0A1P8CWQ3	Bacillus_phage	1.2e-49	41.4
WP_032951428.1\|660682_661027_+	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_032951429.1\|661026_661206_+	hypothetical protein	NA	NA	NA	NA
WP_032951430.1\|661745_662516_+	hypothetical protein	NA	NA	NA	NA
WP_003129567.1\|663245_663917_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-28	36.0
663025:663137	attR	NA	NA	NA	NA
WP_003129569.1\|663919_664993_-	ABC transporter permease	NA	NA	NA	NA
WP_003129571.1\|665004_665574_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_032398871.1\|665761_667285_-	acyl-CoA synthetase	NA	NA	NA	NA
WP_003129577.1\|667475_668393_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_003129579.1\|668653_671017_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	9.5e-108	32.0
WP_003129581.1\|671148_671808_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_010905496.1\|671810_673028_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_003129585.1\|673024_673171_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_014570401.1\|673511_674774_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_003129588.1\|674879_678293_+	pyruvate carboxylase	NA	NA	NA	NA
WP_003129590.1\|678416_679742_+	citrate/2-methylcitrate synthase	NA	NA	NA	NA
WP_003129591.1\|679738_682285_+	aconitate hydratase AcnA	NA	NA	NA	NA
WP_003129592.1\|682305_683544_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_003129593.1\|683609_684209_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.1e-51	52.0

DBSCAN-SWA_6

1086230 : 1100015

Enterococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003130964.1\|1086230_1086923_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	2.7e-31	34.4
WP_014570517.1\|1086915_1087851_+	ABC transporter permease	NA	NA	NA	NA
WP_003130966.1\|1087952_1088930_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	2.4e-118	66.2
WP_003130967.1\|1089279_1091448_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.0e-257	61.1
WP_003130968.1\|1091583_1092006_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	2.3e-12	37.3
WP_012897612.1\|1092007_1092226_-	redoxin NrdH	C3U2K9	Lactococcus_phage	7.6e-12	47.6
WP_003130972.1\|1092399_1093041_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003130974.1\|1093315_1095250_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.4e-125	43.4
WP_003130975.1\|1095454_1095994_+	cysteine hydrolase family protein	NA	NA	NA	NA
WP_003130976.1\|1095986_1096820_+	3'-5' exonuclease	A0A0K2SUJ2	Clostridium_phage	3.1e-21	39.4
WP_003130977.1\|1096816_1097266_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003130980.1\|1097540_1100015_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	4.2e-98	32.2

DBSCAN-SWA_7

1108673 : 1116941

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014570522.1\|1108673_1109762_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	8.4e-51	38.8
WP_003130990.1\|1109761_1110412_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-41	43.6
WP_003130992.1\|1110420_1111617_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.9e-110	50.8
WP_003130993.1\|1111644_1112109_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.8e-39	53.7
WP_003130994.1\|1112211_1112664_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_003130995.1\|1112724_1113630_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	5.4e-11	28.2
WP_003130996.1\|1113776_1114220_+	divergent PAP2 family protein	NA	NA	NA	NA
WP_032398531.1\|1114359_1115982_+	hypothetical protein	NA	NA	NA	NA
WP_014570525.1\|1115984_1116941_+	glycosyltransferase family 2 protein	I1TED8	Salmonella_phage	2.4e-49	37.5

DBSCAN-SWA_8

1236414 : 1304524

Erysipelothrix_phage(59.09%)

head,tail,protease,holin,portal,transposase,capsid,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003130410.1\|1236414_1237362_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	3.4e-32	33.0
WP_003130152.1\|1238316_1238706_+	DUF4430 domain-containing protein	NA	NA	NA	NA
WP_010905797.1\|1238668_1239232_+	hypothetical protein	NA	NA	NA	NA
WP_003130146.1\|1239870_1240218_+	hypothetical protein	NA	NA	NA	NA
WP_021214497.1\|1240696_1242145_+	cardiolipin synthase	NA	NA	NA	NA
WP_081040820.1\|1242702_1245210_+	HAD-IC family P-type ATPase	NA	NA	NA	NA
WP_003130140.1\|1245271_1245967_-	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_003130139.1\|1246126_1246948_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_003130138.1\|1247234_1247480_+	hypothetical protein	NA	NA	NA	NA
WP_162494534.1\|1247686_1249060_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	E4ZFI6	Streptococcus_phage	1.1e-140	56.6
WP_161487264.1\|1249493_1249652_+	hypothetical protein	NA	NA	NA	NA
WP_064973542.1\|1250004_1253964_+	ATP-dependent helicase	S5MMD7	Bacillus_phage	3.2e-31	25.7
WP_081144288.1\|1254077_1254299_+	helix-turn-helix transcriptional regulator	A0A2K5B263	Erysipelothrix_phage	1.3e-11	42.6
WP_064973541.1\|1254291_1255410_+	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	1.4e-56	39.0
WP_064973540.1\|1255393_1256623_+	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	1.8e-25	29.3
WP_064973539.1\|1256741_1258616_+	AAA domain-containing protein	M1NSM1	Streptococcus_phage	1.7e-30	36.2
WP_081144377.1\|1258622_1260077_+	LlaJI family restriction endonuclease	NA	NA	NA	NA
WP_081144289.1\|1260060_1260255_-	helix-turn-helix domain-containing protein	A0A2K5B263	Erysipelothrix_phage	4.8e-10	60.9
WP_081144378.1\|1260293_1262882_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_161487265.1\|1262885_1263680_-	DUF1837 domain-containing protein	NA	NA	NA	NA
WP_081144290.1\|1263823_1264021_-	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	2.5e-14	50.0
WP_064973537.1\|1264010_1264934_-	hypothetical protein	NA	NA	NA	NA
WP_064973536.1\|1265309_1265801_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_081144291.1\|1265864_1266092_+	hypothetical protein	NA	NA	NA	NA
WP_064973534.1\|1266078_1266390_+	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	1.7e-12	47.0
WP_081144292.1\|1266389_1267535_+	DUF2800 domain-containing protein	M1Q218	Streptococcus_phage	7.3e-122	57.9
WP_064973533.1\|1267527_1268079_+	DUF2815 family protein	A0A2K5B2A9	Erysipelothrix_phage	1.0e-76	76.5
WP_064973532.1\|1268141_1268663_+	hypothetical protein	A0A076YKT4	Mycobacterium_phage	1.2e-15	39.3
WP_064973531.1\|1268650_1270603_+	DNA polymerase	A0A2K5B2B0	Erysipelothrix_phage	6.1e-270	67.5
WP_064973530.1\|1270872_1271646_+	phage antirepressor	A0A0A8WIE3	Clostridium_phage	4.2e-65	53.3
WP_064973529.1\|1271638_1271986_+	DUF4406 domain-containing protein	A0A2K5B270	Erysipelothrix_phage	4.6e-27	50.0
WP_064973528.1\|1271978_1274225_+	DNA primase	A0A1B0RXC5	Streptococcus_phage	2.8e-194	47.3
WP_081144293.1\|1274354_1274600_+	hypothetical protein	NA	NA	NA	NA
WP_064973526.1\|1274601_1274889_+	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	3.1e-21	52.1
WP_153040028.1\|1275018_1276245_+	DEAD/DEAH box helicase	A0A2K5B273	Erysipelothrix_phage	1.6e-162	70.6
WP_081144294.1\|1276245_1276674_+	DUF1492 domain-containing protein	A0A2K5B275	Erysipelothrix_phage	3.3e-35	52.5
WP_081144379.1\|1276863_1277223_+	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	1.2e-30	56.6
WP_031641527.1\|1277354_1277933_+\|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	1.2e-53	52.8
WP_081144295.1\|1277937_1278720_+	S-adenosylmethionine synthetase	NA	NA	NA	NA
WP_064973371.1\|1278704_1279322_+	HNH endonuclease	A0A0B5HE03	Vibrio_phage	8.7e-13	37.6
WP_064973370.1\|1279311_1280550_+	site-specific DNA-methyltransferase	A0A2I4R670	Erysipelothrix_phage	2.4e-142	60.7
WP_081144296.1\|1280620_1281001_+	DUF4314 domain-containing protein	A0A2K5B281	Erysipelothrix_phage	3.0e-16	49.4
WP_064973369.1\|1281002_1281197_+	hypothetical protein	NA	NA	NA	NA
WP_064973368.1\|1281180_1281357_+	DUF5049 domain-containing protein	NA	NA	NA	NA
WP_134992078.1\|1281416_1283015_+\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.8e-267	84.2
WP_064973373.1\|1283128_1284064_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	7.7e-37	37.2
WP_153040029.1\|1284125_1284848_+	hypothetical protein	NA	NA	NA	NA
WP_064973365.1\|1284916_1286212_+\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	6.0e-173	72.4
WP_064973364.1\|1286144_1286888_+\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	9.7e-67	58.5
WP_064973363.1\|1286889_1288098_+\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	5.2e-102	48.6
WP_064973362.1\|1288108_1288420_+\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	9.1e-35	71.0
WP_064973361.1\|1288416_1288755_+\|head,tail	head-tail adaptor protein	A0A2K5B291	Erysipelothrix_phage	1.1e-22	52.8
WP_064973360.1\|1288747_1289179_+	HK97 gp10 family phage protein	A0A2K5B292	Erysipelothrix_phage	2.4e-41	60.8
WP_081144298.1\|1289175_1289514_+	hypothetical protein	NA	NA	NA	NA
WP_064973358.1\|1289515_1290106_+\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	1.5e-75	71.5
WP_064973357.1\|1290115_1290496_+	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	2.6e-36	65.0
WP_081144299.1\|1290807_1291155_+	hypothetical protein	NA	NA	NA	NA
WP_081144300.1\|1291248_1293810_+\|tail	phage tail protein	A0A2K5B297	Erysipelothrix_phage	2.6e-82	73.1
WP_064973372.1\|1293825_1294518_+\|tail	phage tail protein	A0A1L2BYA2	Clostridium_phage	4.4e-21	29.0
WP_081144301.1\|1294514_1298576_+	hypothetical protein	A0A1B1P770	Bacillus_phage	3.2e-87	41.4
WP_064973354.1\|1298733_1299147_+	DUF1617 family protein	Q9AZX1	Lactococcus_phage	2.2e-12	48.2
WP_064973353.1\|1299143_1299551_+\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	5.0e-41	60.0
WP_064973352.1\|1299551_1300463_+	N-acetylmuramoyl-L-alanine amidase	A0A1D8ETE4	Propionibacterium_phage	2.6e-29	37.6
WP_064973351.1\|1300627_1300921_+	hypothetical protein	NA	NA	NA	NA
WP_081144302.1\|1300980_1302540_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	5.4e-128	45.1
WP_064973349.1\|1302543_1302972_+	hypothetical protein	A0A2K5B2B3	Erysipelothrix_phage	9.0e-25	45.3
WP_064973348.1\|1302961_1304524_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	5.1e-150	54.7

DBSCAN-SWA_9

1826943 : 1836802

Prochlorococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003130886.1\|1826943_1827705_-	phosphate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.5e-17	30.0
WP_003130885.1\|1827870_1828680_-	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.0e-10	26.5
WP_003130884.1\|1828713_1829607_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_003130883.1\|1829606_1830530_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_003130881.1\|1830650_1831502_-	phosphate ABC transporter substrate-binding protein PstS family protein	E3SNT9	Prochlorococcus_phage	4.2e-05	27.3
WP_003130880.1\|1831848_1832745_-	phosphate ABC transporter substrate-binding protein	E3SM63	Prochlorococcus_phage	7.2e-08	32.4
WP_003130878.1\|1833022_1833490_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.7e-43	56.6
WP_003130877.1\|1833521_1834088_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_081144328.1\|1834183_1836802_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.6e-63	33.7

DBSCAN-SWA_10

1851225 : 1862658

Lactococcus_phage(100.0%)

integrase

attL 1849774:1849789|attR 1863781:1863796

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1849774:1849789	attL	NA	NA	NA	NA
WP_014570681.1\|1851225_1851426_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.4e-28	93.9
WP_003132877.1\|1852545_1852956_-	hypothetical protein	NA	NA	NA	NA
WP_014570682.1\|1852982_1853249_-	hypothetical protein	NA	NA	NA	NA
WP_003132880.1\|1853828_1854008_-	hypothetical protein	Q9AZG2	Lactococcus_phage	4.6e-23	98.3
WP_043991155.1\|1854165_1854438_+	hypothetical protein	NA	NA	NA	NA
WP_014570684.1\|1854502_1854700_-	hypothetical protein	Q9AZG4	Lactococcus_phage	4.1e-09	96.7
WP_003132811.1\|1854883_1855246_-	hypothetical protein	Q9AZG6	Lactococcus_phage	1.7e-56	99.2
WP_003132810.1\|1855263_1855836_-	hypothetical protein	Q9AZG7	Lactococcus_phage	7.9e-93	94.2
WP_003132808.1\|1855997_1856204_-	hypothetical protein	Q9AZG9	Lactococcus_phage	1.4e-31	97.1
WP_003132807.1\|1856222_1856405_-	hypothetical protein	Q9AZH0	Lactococcus_phage	5.3e-27	98.3
WP_003132806.1\|1856774_1858472_-	hypothetical protein	Q9AZH2	Lactococcus_phage	1.0e-244	95.7
WP_003132804.1\|1858481_1858751_-	hypothetical protein	Q9AZH3	Lactococcus_phage	2.0e-38	95.5
WP_162467663.1\|1858747_1858885_-	hypothetical protein	Q9AZH4	Lactococcus_phage	1.5e-13	86.7
WP_153951771.1\|1858910_1859078_-	hypothetical protein	NA	NA	NA	NA
WP_003132801.1\|1859152_1859845_-	Bro-N domain-containing protein	NA	NA	NA	NA
WP_003132799.1\|1859847_1860072_-	hypothetical protein	NA	NA	NA	NA
WP_014570685.1\|1860288_1860519_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014570686.1\|1860676_1861354_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014570687.1\|1861446_1862658_+\|integrase	site-specific integrase	Q9AZI0	Lactococcus_phage	4.4e-117	54.4
1863781:1863796	attR	NA	NA	NA	NA

DBSCAN-SWA_11

1887890 : 1956569

Lactococcus_phage(75.0%)

tail,head,integrase,portal,terminase,transposase,plate,capsid,holin

attL 1915175:1915196|attR 1952648:1952669

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081144275.1\|1887890_1888838_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	1.3e-31	33.0
WP_032398785.1\|1888941_1890861_-	hypothetical protein	NA	NA	NA	NA
WP_004255282.1\|1890882_1891524_-	hypothetical protein	NA	NA	NA	NA
WP_004255278.1\|1891639_1892065_-	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_010906126.1\|1892249_1893659_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_004255268.1\|1893791_1894661_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_004255265.1\|1894676_1896179_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_004255262.1\|1896365_1896893_-	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_004255258.1\|1896894_1897401_-	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_004255255.1\|1897415_1898129_-	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_004255250.1\|1898173_1898389_-	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_004255244.1\|1898572_1899349_-	esterase family protein	NA	NA	NA	NA
WP_081144329.1\|1899633_1901844_-	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	5.5e-49	55.1
WP_004255240.1\|1901824_1902472_-	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_004255239.1\|1902531_1903893_-	ABC transporter permease	NA	NA	NA	NA
WP_004255238.1\|1903889_1904822_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.8e-23	30.2
WP_004255236.1\|1904926_1905325_-	hypothetical protein	NA	NA	NA	NA
WP_004255233.1\|1905428_1905992_-	N-acetyltransferase	NA	NA	NA	NA
WP_021214596.1\|1906164_1907343_-	cation transporter	NA	NA	NA	NA
WP_004255229.1\|1907723_1908380_-	thiaminase II	NA	NA	NA	NA
WP_010906134.1\|1908415_1908721_-	hypothetical protein	NA	NA	NA	NA
WP_004255227.1\|1908737_1909709_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_004255224.1\|1909714_1910284_-	biotin transporter BioY	NA	NA	NA	NA
WP_004255221.1\|1910428_1911670_+	AMP-binding protein	NA	NA	NA	NA
WP_004255218.1\|1911659_1912808_+	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
WP_004255217.1\|1912804_1913155_+	hypothetical protein	NA	NA	NA	NA
WP_004255215.1\|1913129_1913423_+	hypothetical protein	NA	NA	NA	NA
WP_004255213.1\|1913410_1914166_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004255210.1\|1914188_1915034_+	2-nitropropane dioxygenase	NA	NA	NA	NA
1915175:1915196	attL	NA	NA	NA	NA
WP_063283927.1\|1915363_1915834_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143468201.1\|1915969_1916638_-	hypothetical protein	NA	NA	NA	NA
WP_081144331.1\|1916732_1918022_-	LysM peptidoglycan-binding domain-containing protein	A0A1P8BKY1	Lactococcus_phage	5.5e-243	98.4
WP_081144332.1\|1918018_1918369_-\|holin	holin	A0A1X9IGI3	Lactococcus_phage	2.6e-38	68.1
WP_081144333.1\|1918481_1921526_-\|plate	BppU family phage baseplate upper protein	A0A1P8BM97	Lactococcus_phage	3.5e-86	87.8
WP_081144334.1\|1921538_1924424_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1P8BKT8	Lactococcus_phage	0.0e+00	97.6
WP_081144335.1\|1924423_1925185_-\|tail	phage tail protein	Q9AZ58	Lactococcus_phage	8.2e-138	96.8
WP_081144336.1\|1925198_1927823_-	tape measure protein	A0A1P8BLX4	Lactococcus_phage	2.3e-264	98.5
WP_061778133.1\|1927838_1928108_-	hypothetical protein	A0A1P8BKT4	Lactococcus_phage	1.5e-41	98.9
WP_081144337.1\|1928191_1928542_-	hypothetical protein	A0A1P8BLS4	Lactococcus_phage	1.2e-56	98.3
WP_081144338.1\|1928657_1929155_-\|tail	phage major tail protein, TP901-1 family	Q38612	Lactococcus_phage	2.8e-86	99.4
WP_081144339.1\|1929165_1929561_-\|capsid	phage capsid protein	A0A1P8BM84	Lactococcus_phage	3.7e-65	97.7
WP_081144340.1\|1929557_1929917_-	hypothetical protein	B5SP35	Lactococcus_phage	3.8e-61	98.3
WP_081144341.1\|1929913_1930225_-	hypothetical protein	Q8LTQ6	Lactococcus_phage	4.6e-55	99.0
WP_003131944.1\|1930221_1930554_-\|head,tail	phage head-tail connector protein	A0A1P8BMC5	Lactococcus_phage	7.1e-54	100.0
WP_014570729.1\|1930540_1930738_-	hypothetical protein	B5SP32	Lactococcus_phage	2.8e-29	100.0
WP_058207139.1\|1930737_1931559_-\|capsid	N4-gp56 family major capsid protein	B5SP31	Lactococcus_phage	3.9e-141	99.3
WP_081144342.1\|1931560_1932223_-	DUF4355 domain-containing protein	B5SP30	Lactococcus_phage	1.9e-77	99.5
WP_081144343.1\|1932348_1932597_-	hypothetical protein	A0A1P8BM59	Lactococcus_phage	4.0e-41	98.8
WP_081144344.1\|1932655_1932988_-	hypothetical protein	A0A1P8BMG7	Lactococcus_phage	4.8e-58	100.0
WP_081144345.1\|1933033_1934074_-\|capsid	minor capsid protein	A0A1P8BM04	Lactococcus_phage	7.4e-190	97.1
WP_153040030.1\|1934077_1935439_-\|portal	phage portal protein	A0A1P8BKU9	Lactococcus_phage	1.6e-248	97.1
WP_081144346.1\|1935439_1936828_-\|terminase	phage terminase large subunit	Q9AZ66	Lactococcus_phage	1.4e-271	98.9
WP_081144347.1\|1936820_1937222_-	hypothetical protein	A0A1P8BM76	Lactococcus_phage	4.4e-66	99.2
WP_081144348.1\|1937385_1937844_-	hypothetical protein	A0A1P8BM80	Lactococcus_phage	8.3e-85	100.0
WP_081144349.1\|1937847_1938159_-	hypothetical protein	A0A1P8BM61	Lactococcus_phage	1.9e-53	99.0
WP_161487266.1\|1938155_1938365_-	hypothetical protein	A0A1P8BMB3	Lactococcus_phage	2.6e-30	100.0
WP_081144351.1\|1938361_1938718_-	DUF1064 domain-containing protein	A0A1P8BMB7	Lactococcus_phage	7.7e-62	100.0
WP_081144352.1\|1938717_1939380_-	DUF1642 domain-containing protein	A0A1P8BM44	Lactococcus_phage	4.6e-36	49.3
WP_063283791.1\|1939372_1939594_-	hypothetical protein	A0A097BY46	Enterococcus_phage	8.8e-08	30.1
WP_081144353.1\|1939920_1942206_-	AAA family ATPase	Q5YA88	Bacillus_phage	1.4e-241	56.1
WP_081144354.1\|1942208_1943804_-	DEAD/DEAH box helicase	A0A097BY72	Enterococcus_phage	1.5e-205	66.7
WP_046781502.1\|1943778_1944039_-	hypothetical protein	NA	NA	NA	NA
WP_081144355.1\|1944700_1945744_-	ATP-binding protein	Q5YA96	Bacillus_phage	5.2e-82	45.7
WP_063283787.1\|1945753_1946398_-	HNH endonuclease	A0A1P8BMP7	Lactococcus_phage	3.9e-104	87.9
WP_153040031.1\|1946385_1947666_-	AAA family ATPase	A0A097BY67	Enterococcus_phage	2.3e-140	60.1
WP_063283786.1\|1947669_1947879_-	helix-turn-helix transcriptional regulator	Q8LTN5	Lactococcus_phage	4.0e-18	59.4
WP_081144356.1\|1947886_1948282_-	hypothetical protein	NA	NA	NA	NA
WP_063283785.1\|1948330_1948585_-	hypothetical protein	NA	NA	NA	NA
WP_063283784.1\|1948593_1948854_-	hypothetical protein	Q9AZF3	Lactococcus_phage	4.3e-46	97.7
WP_011676017.1\|1948867_1949098_-	hypothetical protein	NA	NA	NA	NA
WP_063283793.1\|1949387_1949735_+	XRE family transcriptional regulator	Q9AZJ7	Lactococcus_phage	4.6e-27	50.9
WP_063283783.1\|1949763_1950330_+	hypothetical protein	A0A1P8BM30	Lactococcus_phage	3.8e-55	60.4
WP_063283782.1\|1950348_1951182_+	DUF4428 domain-containing protein	O48432	Lactobacillus_phage	3.3e-15	25.3
WP_081144357.1\|1951304_1952444_+\|integrase	site-specific integrase	A0A1X9IGD8	Lactococcus_phage	1.6e-153	73.1
WP_004255207.1\|1952647_1954060_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
1952648:1952669	attR	NA	NA	NA	NA
WP_004255197.1\|1954293_1954752_-	SUF system NifU family Fe-S cluster assembly protein	A0A218MM29	uncultured_virus	9.1e-07	33.0
WP_004255194.1\|1954867_1955350_-	hypothetical protein	NA	NA	NA	NA
WP_004255189.1\|1955351_1956569_-	cysteine desulfurase	Q2XUY6	environmental_halophage	4.0e-110	46.3

DBSCAN-SWA_12

2021003 : 2104105

100

Lactococcus_phage(77.42%)

tail,head,integrase,portal,terminase,transposase,plate,tRNA,capsid,holin

attL 2065802:2065824|attR 2104124:2104146

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003132359.1\|2021003_2022881_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_014570709.1\|2023253_2023829_-	hypothetical protein	NA	NA	NA	NA
WP_014570710.1\|2023961_2024330_-	DUF1033 family protein	NA	NA	NA	NA
WP_003132362.1\|2024445_2024847_-	Mini-ribonuclease 3	NA	NA	NA	NA
WP_010906168.1\|2024839_2026186_-\|tRNA	cysteine--tRNA ligase	A0A2K9V966	Bandra_megavirus	3.1e-47	29.5
WP_003132364.1\|2026198_2026792_-	DUF1211 domain-containing protein	NA	NA	NA	NA
WP_003132365.1\|2026805_2027405_-	serine O-acetyltransferase	NA	NA	NA	NA
WP_003132366.1\|2027511_2028282_-	hypothetical protein	NA	NA	NA	NA
WP_003132367.1\|2028490_2030812_-	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_014570712.1\|2031095_2032241_-	hypothetical protein	NA	NA	NA	NA
WP_003132369.1\|2032605_2033571_+	ribose-phosphate diphosphokinase	A0A2K9L2G2	Tupanvirus	2.3e-36	32.8
WP_003132370.1\|2033692_2034124_-	universal stress protein	NA	NA	NA	NA
WP_010906171.1\|2034363_2035491_+	cysteine desulfurase	H7BUW1	unidentified_phage	2.2e-30	36.0
WP_003132372.1\|2035514_2035859_+	DUF1831 domain-containing protein	NA	NA	NA	NA
WP_003132374.1\|2035949_2037137_-	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	2.0e-34	29.4
WP_003132378.1\|2037379_2037562_+	hypothetical protein	NA	NA	NA	NA
WP_014570713.1\|2037620_2037737_+	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_003132382.1\|2037794_2040593_-\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	3.6e-82	25.9
WP_003132384.1\|2040908_2041835_-	DivIVA domain-containing protein	NA	NA	NA	NA
WP_010906173.1\|2041891_2042683_-	RNA-binding protein	NA	NA	NA	NA
WP_010906174.1\|2042679_2042955_-	YggT family protein	NA	NA	NA	NA
WP_003132390.1\|2042954_2043545_-	cell division protein SepF	NA	NA	NA	NA
WP_003132391.1\|2043578_2044256_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_003132392.1\|2044259_2045513_-	cell division protein FtsZ	NA	NA	NA	NA
WP_003132393.1\|2045543_2046914_-	cell division protein FtsA	NA	NA	NA	NA
WP_010906175.1\|2047074_2047944_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	3.8e-14	35.3
WP_003132395.1\|2048056_2048785_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	A0A2D1A6G0	Rhodococcus_phage	1.2e-05	27.8
WP_010906176.1\|2048930_2050049_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_003132398.1\|2050179_2051025_-	aldo/keto reductase	A0A1V0SDE7	Indivirus	4.8e-30	32.9
WP_003132399.1\|2051036_2052365_-	MFS transporter	NA	NA	NA	NA
WP_003130410.1\|2052479_2053427_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	3.4e-32	33.0
WP_003130787.1\|2053610_2054489_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003130788.1\|2054504_2054909_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_032398888.1\|2054990_2056301_-	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	9.7e-62	31.5
WP_003130792.1\|2056429_2057023_-	HD domain-containing protein	NA	NA	NA	NA
WP_003130794.1\|2057080_2057761_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_003130796.1\|2057793_2058072_-	hypothetical protein	NA	NA	NA	NA
WP_003130797.1\|2058064_2058649_-	NUDIX hydrolase	NA	NA	NA	NA
WP_081144360.1\|2058753_2060130_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A0G2Y8M0	Acanthamoeba_polyphaga_mimivirus	9.3e-31	35.3
WP_012898440.1\|2060357_2061146_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.7e-32	33.6
WP_010906184.1\|2061224_2061494_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_003130801.1\|2061675_2063559_-	Stk1 family PASTA domain-containing Ser/Thr kinase	A0A1V0SDC3	Indivirus	3.1e-21	31.6
WP_003130802.1\|2063558_2064335_-	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_014570715.1\|2064415_2065690_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
2065802:2065824	attL	NA	NA	NA	NA
WP_014570716.1\|2066643_2067423_-	muramidase	Q9AZW7	Lactococcus_phage	8.7e-127	98.1
WP_014570717.1\|2067422_2067710_-\|holin	phage holin	Q9AZL0	Lactococcus_phage	2.8e-46	96.8
WP_014570718.1\|2067722_2068073_-	hypothetical protein	A5GYT0	Lactococcus_phage	1.7e-53	97.4
WP_014570720.1\|2068462_2070820_-\|plate	BppU family phage baseplate upper protein	A0A1P8BM97	Lactococcus_phage	5.2e-74	81.7
WP_014570721.1\|2070837_2073591_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1P8BLR1	Lactococcus_phage	0.0e+00	95.8
WP_014570722.1\|2073590_2074352_-	hypothetical protein	Q9AYV7	Lactococcus_phage	3.3e-139	97.6
WP_014570723.1\|2074361_2077175_-\|tail	phage tail tape measure protein	Q9G097	Lactococcus_phage	5.2e-270	90.5
WP_014570724.1\|2077188_2077452_-	hypothetical protein	Q9AZ59	Lactococcus_phage	1.4e-41	97.7
WP_014570725.1\|2077547_2077883_-	hypothetical protein	Q77RZ7	Lactococcus_phage	4.2e-54	99.1
WP_014570726.1\|2077998_2078496_-\|tail	phage major tail protein, TP901-1 family	A0A1P8BM54	Lactococcus_phage	9.0e-85	97.6
WP_014570727.1\|2078506_2078902_-	hypothetical protein	A0A1P8BM84	Lactococcus_phage	5.1e-67	100.0
WP_014570728.1\|2078898_2079237_-	HK97 gp10 family phage protein	Q77K21	Lactococcus_phage	7.3e-54	97.3
WP_003131945.1\|2079233_2079545_-	hypothetical protein	Q8LTQ6	Lactococcus_phage	1.8e-54	98.1
WP_003131944.1\|2079541_2079874_-\|head,tail	phage head-tail connector protein	A0A1P8BMC5	Lactococcus_phage	7.1e-54	100.0
WP_014570729.1\|2079860_2080058_-	hypothetical protein	B5SP32	Lactococcus_phage	2.8e-29	100.0
WP_058207139.1\|2080057_2080879_-\|capsid	N4-gp56 family major capsid protein	B5SP31	Lactococcus_phage	3.9e-141	99.3
WP_081144361.1\|2080880_2081543_-	DUF4355 domain-containing protein	B5SP30	Lactococcus_phage	4.9e-78	100.0
WP_043991226.1\|2081657_2081867_-	hypothetical protein	A0A1P8BKS4	Lactococcus_phage	2.5e-28	95.5
WP_014570733.1\|2081908_2082136_-	hypothetical protein	A0A1P8BL44	Lactococcus_phage	7.3e-34	98.6
WP_025016873.1\|2083848_2084037_-	hypothetical protein	A0A1P8BM11	Lactococcus_phage	1.1e-24	98.4
WP_014570736.1\|2084023_2085412_-\|portal	phage portal protein	A0A1P8BM37	Lactococcus_phage	2.2e-237	90.9
WP_014570737.1\|2085425_2086814_-\|terminase	phage terminase large subunit	Q8LTR4	Lactococcus_phage	9.1e-268	98.5
WP_003131930.1\|2086806_2087223_-	hypothetical protein	Q9AZ67	Lactococcus_phage	1.6e-58	87.7
WP_010905372.1\|2087578_2088001_-	RinA family protein	Q9AZM9	Lactococcus_phage	8.5e-52	100.0
WP_014570738.1\|2088677_2088863_-	hypothetical protein	R9QMC5	Lactococcus_phage	4.1e-27	100.0
WP_014570739.1\|2088870_2089074_-	hypothetical protein	NA	NA	NA	NA
WP_043991165.1\|2089196_2089373_-	DUF1660 domain-containing protein	A0A1P8BLJ5	Lactococcus_phage	1.5e-26	98.1
WP_063283376.1\|2089590_2090271_-	hypothetical protein	A0A1P8BK99	Lactococcus_phage	3.1e-128	99.1
WP_014570742.1\|2090297_2090570_-	hypothetical protein	A0A1P8BKH9	Lactococcus_phage	1.8e-42	87.8
WP_003129863.1\|2090573_2090993_-	dUTP diphosphatase	A0A1P8BLJ0	Lactococcus_phage	3.9e-73	100.0
WP_143468752.1\|2090989_2091685_-	DUF1642 domain-containing protein	A0A1P8BKG5	Lactococcus_phage	2.4e-120	98.7
WP_043991166.1\|2091656_2091836_-	hypothetical protein	A0A1P8BKQ8	Lactococcus_phage	5.2e-27	100.0
WP_014570743.1\|2091832_2092033_-	DUF1125 domain-containing protein	Q9MC26	Lactococcus_phage	2.4e-28	98.5
WP_014570535.1\|2092224_2092431_-	hypothetical protein	Q9MC28	Lactococcus_phage	4.8e-32	100.0
WP_014570744.1\|2092541_2092781_-	DUF1031 family protein	A0A1P8BKN9	Lactococcus_phage	2.8e-36	96.2
WP_014570745.1\|2092773_2092968_-	hypothetical protein	Q9B005	Lactococcus_phage	1.6e-26	96.9
WP_014570746.1\|2092970_2093360_-	RusA family crossover junction endodeoxyribonuclease	Q9MC30	Lactococcus_phage	7.1e-69	100.0
WP_081144362.1\|2094420_2095233_-	replication protein	A0A1P8BL25	Lactococcus_phage	3.8e-56	98.1
WP_014570750.1\|2095357_2095783_-	single-stranded DNA-binding protein	Q9MC32	Lactococcus_phage	8.8e-73	96.5
WP_014570751.1\|2095775_2096534_-	hypothetical protein	Q0ILF6	Lactococcus_phage	3.1e-145	98.4
WP_014570752.1\|2096542_2097061_-	hypothetical protein	Q9XJE3	Lactococcus_phage	3.8e-86	97.1
WP_014570753.1\|2097160_2097388_-	hypothetical protein	A0A1P8BKS9	Lactococcus_phage	4.0e-32	96.0
WP_014570754.1\|2097389_2097590_-	helix-turn-helix transcriptional regulator	A0A1P8BL04	Lactococcus_phage	6.9e-12	97.1
WP_014570755.1\|2097740_2098019_+	DUF3892 domain-containing protein	NA	NA	NA	NA
WP_014570756.1\|2098048_2098243_-	hypothetical protein	A0A1P8BKZ2	Lactococcus_phage	7.4e-27	96.9
WP_014570757.1\|2098337_2098607_-	hypothetical protein	NA	NA	NA	NA
WP_014570758.1\|2098619_2099387_-	phage repressor protein/antirepressor Ant	A0A1B1IMQ3	Lactococcus_phage	4.0e-124	89.0
WP_023189646.1\|2099399_2099639_-	helix-turn-helix transcriptional regulator	Q38329	Lactococcus_phage	1.4e-35	97.5
WP_014570760.1\|2099744_2100002_+	hypothetical protein	A7TWL9	Staphylococcus_phage	1.1e-14	58.8
WP_014570761.1\|2099991_2100201_-	hypothetical protein	NA	NA	NA	NA
WP_014570762.1\|2100355_2100898_+	hypothetical protein	NA	NA	NA	NA
WP_080554627.1\|2101029_2101242_-	putative transcriptional regulator	A0A1B1IMU6	Lactococcus_phage	5.8e-25	93.5
WP_014570764.1\|2101504_2102068_+	helix-turn-helix transcriptional regulator	Q38327	Lactococcus_phage	5.1e-60	84.7
WP_014570765.1\|2102073_2102508_+	zinc peptidase	NA	NA	NA	NA
WP_014570766.1\|2102521_2102857_+	hypothetical protein	NA	NA	NA	NA
WP_058207138.1\|2102923_2104105_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	1.5e-90	47.5
2104124:2104146	attR	NA	NA	NA	NA

DBSCAN-SWA_13

2402620 : 2419901

Lactococcus_phage(85.71%)

head,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003131963.1\|2402620_2402815_-	hypothetical protein	Q9AZK6	Lactococcus_phage	3.7e-10	62.3
WP_003131964.1\|2404682_2404940_-	hypothetical protein	NA	NA	NA	NA
WP_014570835.1\|2405228_2405423_-	hypothetical protein	Q9AZK1	Lactococcus_phage	2.5e-27	96.9
WP_014570836.1\|2405436_2405988_-	hypothetical protein	Q9AZJ8	Lactococcus_phage	1.4e-86	79.9
WP_014570837.1\|2405999_2406383_-	helix-turn-helix transcriptional regulator	Q9AZJ7	Lactococcus_phage	1.8e-45	70.1
WP_014570838.1\|2406640_2406838_+	hypothetical protein	Q9AZJ6	Lactococcus_phage	1.4e-20	81.2
WP_080554629.1\|2406841_2407087_+	hypothetical protein	NA	NA	NA	NA
WP_043991180.1\|2407271_2408090_-	TIGR02391 family protein	A0A059NT45	Lactococcus_phage	1.8e-82	57.1
WP_014570840.1\|2408167_2408353_+	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	2.4e-06	44.3
WP_011677056.1\|2408471_2408666_+	DUF1655 domain-containing protein	Q9AZF2	Lactococcus_phage	1.1e-27	95.3
WP_014570841.1\|2408670_2409096_+	hypothetical protein	Q9AZF1	Lactococcus_phage	3.5e-69	90.8
WP_014570842.1\|2409107_2409389_+	hypothetical protein	Q9AZJ1	Lactococcus_phage	1.5e-41	89.2
WP_014570843.1\|2409431_2409671_+	hypothetical protein	Q9AZJ0	Lactococcus_phage	8.8e-38	94.9
WP_014570844.1\|2409918_2410230_+	hypothetical protein	NA	NA	NA	NA
WP_014570845.1\|2410226_2410556_+	hypothetical protein	Q9AZI7	Lactococcus_phage	9.3e-54	93.6
WP_014570846.1\|2410559_2411354_+	hypothetical protein	Q9AZI6	Lactococcus_phage	1.4e-143	90.9
WP_014570847.1\|2411364_2412999_+	DNA primase	Q9AZI5	Lactococcus_phage	1.2e-290	91.0
WP_003131978.1\|2413208_2413391_+	hypothetical protein	Q9AZE3	Lactococcus_phage	7.9e-23	93.1
WP_014570848.1\|2413416_2414025_+	hypothetical protein	Q9AZE2	Lactococcus_phage	1.4e-84	87.1
WP_014570849.1\|2414033_2414624_+\|head,protease	HK97 family phage prohead protease	Q9AZE1	Lactococcus_phage	2.7e-104	96.4
WP_058207066.1\|2414837_2415167_+	hypothetical protein	Q9AZE0	Lactococcus_phage	8.7e-52	95.4
WP_043991183.1\|2415269_2415578_+	sigma-70 family RNA polymerase sigma factor	Q9AZD9	Lactococcus_phage	7.3e-45	92.2
WP_003131983.1\|2416306_2416507_+	hypothetical protein	NA	NA	NA	NA
WP_003131984.1\|2416565_2417906_-	type I glutamate--ammonia ligase	A0A2P1EM84	Moumouvirus	1.8e-10	23.7
WP_003131985.1\|2417967_2418333_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003131986.1\|2418433_2418871_-	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_003131990.1\|2419283_2419901_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.9e-09	28.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP016699

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP015897

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection