CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020773	Staphylococcus lutrae strain ATCC 700373 chromosome, complete genome	3 crisprs	RT,DEDDh,cas2,cas1,WYL,cas9,cas3,csa3,DinG	0	10	15	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020773_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020773_1

324108-324247

Orphan

Consensus_repeat	Method
AAAATGGAGCGGAAGATAGGACTTGCACCTATACCTCTTTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020773_1

>merge|NZ_CP020773|1|324108-324247|CRISPRCasFinder
AAAATGGAGCGGAAGATAGGACTTGCACCTATACCTCTTTCCGGGAAGGAAAGTGTTCTAGAATTGAACTACTCCCGCAGGATAAACATGTTCTATTAAAAATGGAGCGGAAGATAGGACTTGCACCTATACCCCTTTCC

>NZ_CP020773|1|1|324108-324247|CRISPRCasFinder
AAAATGGAGCGGAAGATAGGACTTGCACCTATACCTCTTTCC	GGGAAGGAAAGTGTTCTAGAATTGAACTACTCCCGCAGGATAAACATGTTCTATTA
AAAATGGAGCGGAAGATAGGACTTGCACCTATACCCCTTTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020773.1\|WP_085236462.1\|339961_341698_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP020773.1\|WP_085236467.1\|342638_343691_-\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_CP020773.1\|WP_085236456.1\|335503_336790_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493
NZ_CP020773.1\|WP_142382186.1\|318605_318857_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP020773.1\|WP_085236458.1\|336883_337978_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP020773.1\|WP_085236447.1\|320897_322445_+\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_CP020773.1\|WP_085236464.1\|342034_342577_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NZ_CP020773.1\|WP_103322067.1\|318828_319958_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP020773.1\|WP_085236434.1\|311407_312139_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP020773.1\|WP_085236435.1\|312131_313592_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP020773.1\|WP_085236441.1\|318270_318558_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP020773.1\|WP_085236454.1\|334962_335421_-\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|224146
NZ_CP020773.1\|WP_085236437.1\|315088_316468_-\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NZ_CP020773.1\|WP_085238394.1\|322548_323889_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP020773.1\|WP_085236452.1\|334005_334956_-\|hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
NZ_CP020773.1\|WP_085236460.1\|338115_339708_-\|FMN-binding-glutamate-synthase-family-protein	unknown	unknown	gnl\|CDD\|223147
NZ_CP020773.1\|WP_085236449.1\|333465_333924_-\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NZ_CP020773.1\|WP_085238395.1\|332101_333421_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP020773.1\|WP_085236444.1\|320038_320638_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP020773.1\|WP_085236436.1\|313797_314856_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167

Protein	Function_ID	Function_description	E-value
NZ_CP020773.1\|WP_085236462.1\|339961_341698_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP020773.1\|WP_085236467.1\|342638_343691_-\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	4.5714e-127
NZ_CP020773.1\|WP_085236456.1\|335503_336790_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
NZ_CP020773.1\|WP_142382186.1\|318605_318857_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.11391e-11
NZ_CP020773.1\|WP_085236458.1\|336883_337978_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	7.2346e-55
NZ_CP020773.1\|WP_085236447.1\|320897_322445_+\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	6.6477e-08
NZ_CP020773.1\|WP_085236464.1\|342034_342577_-\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	7.74778e-128
NZ_CP020773.1\|WP_103322067.1\|318828_319958_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.67209e-52
NZ_CP020773.1\|WP_085236434.1\|311407_312139_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	6.18697e-151
NZ_CP020773.1\|WP_085236435.1\|312131_313592_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	9.42064e-96
NZ_CP020773.1\|WP_085236441.1\|318270_318558_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	2.51538e-08
NZ_CP020773.1\|WP_085236454.1\|334962_335421_-\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	3.04581e-67
NZ_CP020773.1\|WP_085236437.1\|315088_316468_-\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	3.61e-13
NZ_CP020773.1\|WP_085238394.1\|322548_323889_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.65506e-61
NZ_CP020773.1\|WP_085236452.1\|334005_334956_-\|hydroxyacid-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	7.15613e-145
NZ_CP020773.1\|WP_085236460.1\|338115_339708_-\|FMN-binding-glutamate-synthase-family-protein	gnl\|CDD\|223147	COG0069, GltB, Glutamate synthase domain 2 [Amino acid transport and metabolism].	2.14484e-145
NZ_CP020773.1\|WP_085236449.1\|333465_333924_-\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	3.73808e-52
NZ_CP020773.1\|WP_085238395.1\|332101_333421_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.51204e-61
NZ_CP020773.1\|WP_085236444.1\|320038_320638_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.36457e-75
NZ_CP020773.1\|WP_085236436.1\|313797_314856_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.43664e-103

>NZ_CP020773.1|WP_085238394.1|322548_323889_+|ISL3-family-transposase
MLKDTVRQVTELKKKLNLKVSNLKITECLGIQTFKNVQSLFYKGVLTYQPKGCECCGIKNEQHTVIKNGFRSTRVYMGLILERPSYLVLKKQRFYCKACGQTFTAKTPYIEPRCTISNDVKLMVTRKLATVISEKDIANSVLVSPSTVHRYLKDLGEAVKTQPSDILPQHLSFDEFKSTNDVDSSMSFIYCDSITHDIIDILPDRRKFKLEEYFLRFSRKQREGVKSVSIDMYPPYMSLIQSLFPNADIILDRFHIVQAVNREINHSRVKTMNSFKTKEKPKYNKLKRYWKLLLKSPIELDRVHYHSFRLFNTWHSQYSLVQFLLTFDEEFQLTYEAGHHILETLRSNNIEQLEEALQRSKSLNISNGLKRVINTLIKYIPYISNTIQNPHLTNGPIEGINNKIKLIKRVSYGYRNFYNFRNRILIISRLYVSEYKKRTKQQKIAT
>NZ_CP020773.1|WP_085236447.1|320897_322445_+|SAP-domain-containing-protein
MKAKQRDKDLFLNKFPNCRIIIETTGTTNYQGTEYNGSIIASFEEIAFVCEKKNFIYVIPWSDINSVSSKKTFMTNNIYLTYDDSSKNLTFKFTNVESVTAIEVLSRAVNEHKMMLKAHDDLLYSKEKEIVFLEKDLNRIKSELDYTNNELKKGNVSEIKPNEIQKTPLQKEKTTPKTELKIDDVHTKEDELIEEANTNKNEHVQHVEIKSDSTQETELNVYDILILHLNNKRIVGKELTNHYLLIEKQIDTMFHIENLLKNGVLSIKSDFNHSLSYLKVPELKSILKDNGLKVSGNKPELMKRIKEDIKEEDVNLPKIYIATHAGEKIIENTNYVLHFFYQPYIINLSVAHKLVKNQYNIDDKIEFIYLKLIENKKQDSHSLKSVVQRLTHYYKTIKKDKSVIRKFTNYAIYLEFIQGLEHFEFNIKYRSIKGSLLEIFYIDTESLEYYEDLILVEDINLNVLKKLFFADVSSFVYADKNICDDFCDILFCHVNRNTNISINQLPAIRNYISSE
>NZ_CP020773.1|WP_085236444.1|320038_320638_+|IS3-family-transposase
MKEMGIRSITKKKYKATTDSKHNLPIYPNLLNQQFKVEKPGVVWVSDITYIYTREGWLYLATVMDLFSRRIIGWSMSNRMTKDLVISALERAFTAQQPTAGLIHHSDRGSQYASIEYQNILRENEIITSMSRKGKCYDNACIESFHSIIKKELIHHCNFQTRNEVMFRIIEYIVTFYNSKRIHSTLNYLSPLEFEKMFS
>NZ_CP020773.1|WP_103322067.1|318828_319958_-|IS3-family-transposase
MTRERRTFSSEFKLQMVRLYENGKPRNEIVREYDLTPSALGKWIKQHQNTGSFHHQDNLSDDEKELIKLRKEVQHLKMENDIFKASSADHGTKIEIIQKNAHQYSVSAMCKVLKIPRSTYYESIKRNTQSQKDDDLELEKIIIDTFNSNRKSFGTRRIKNKLNDKGLTVSRRKIGRIMKKYNLVSVYTKAKYKNHPKETNEKLIKNHLNRTFNREQPMDALVSDLTYVKVADRWHYICLFIDLFNREIVGYSAGKNKDANLVVKAISKINHNLKQIALFHTDRGKEFDNKLIDEVLKTFEIERSLSTKGCPYDNAVAEATMKALKTEFVKQMKFENLEQLETELFDYVNWYNNFRPHSSLQYLTPVAFKDLHMKSV
>NZ_CP020773.1|WP_142382186.1|318605_318857_+|IS3-family-transposase
MCKVLGVSKSGYYDWKKRPTSSQQKRRDRLKKEIYKVYIGNQKRYGSPKITKELMKEGIKVSQRTVTILECQQFPRHFSCVDL
>NZ_CP020773.1|WP_085236441.1|318270_318558_+|transposase
MTKRRYEHYFKMEAIKLVESGRKVTEVSRDLDIPIQTLTKWLSKYREGGEASFVGSGKLTPVKQTEVELQKRLKELEEENRILKKAMHIFAKDQK
>NZ_CP020773.1|WP_085236437.1|315088_316468_-|MAP-domain-containing-protein
MNMKKVMVTGLALGILTSTASLTAGNNADAASQYQHKVQSKTVSYTTTIDGSTSYVQSYLKLSTTSTSNFYQLNEKVKTTLKHEYNVTSLQIKKSKTTQYTVTWKNGKKQTINLKQGSVTPTQKINVNDIKNIDIKVENKKTNYKENSVPYTATIDGATAYVQSYLKLTEKNANNFYQLNQNIKGVLEKEYKLGASQIEKSKAAAYTVTWKNGHKQTISLKQGAALPTQLINIFDIKRIDIDVMSKQEKQVVKSVPYTTTIDGATSFVQSYLKLSNSNANNFYQLNQNIKAALENEYKLSASQVEKSKTAEYTVTWKNGHKQTISLKQGAILPTNVINVQDIKSIDVNVKKGKAKSAVNAVPYAVTLNGNTVFVQSYLHLSNYSASNFHQLNNEVKSVLKHGYRVTDAQIDSAKTAQYTVTWKNGQKQTISLKSDAPLTANKIDIHQIKSIDINVNGVK
>NZ_CP020773.1|WP_085236436.1|313797_314856_-|PTS-transporter-subunit-IIC
MVTNQINKKQFFSVILNAVGAGVVIALLPNALLGELLKFFKEGRPFLESMYQLVLVIQSFMAFIIGALAAHAFKFPGPGVAFVGTSAMIGSGVIQFKNGAFMLHGIGDIINVIIVVMIASILFILLSGKLGSLEIIILPAVIPVISGMLGLFTLPYVSQVTQSLGKLIHTFTELNPLVMSILIAITYALLMVTPISVVAIATAISLSGLGSGAANMGVVAACVTFLMGSWKVNGLGVNIVLLVGAAKMMIPVYLKNPIIMIPLTINGIVSGLIAYTIGIQGTPMSAGFGYSGFVGPINAFNRMEGNPTINILLLILGYFIIPFVIGWVVHQFSKKLLPRYSNDIFRFEIPKE
>NZ_CP020773.1|WP_085236435.1|312131_313592_-|ABC-transporter-permease-subunit
MKHLRKGLSMLFIVLLLFTGLPMTKKAEAASKDQWEVIKERGELKVGLSADYAPMEFEHTVNGEREYAGIDIEIAKKIAKDNGVKLKIVNMSFDSLLGALKTGKIDIIISGMTPTDERKKEVDFSDNYMTVGQTAVVRKKDKDKYKTLKDLANHRIGVQKQTTQEELAKKEIEGADIQSLTRLPEVILALKSNKVDAIVMDSAVGKAYLAQNEDLTFSDATFADSDKPTAIAVPKDSPELLSRINKTIAEVNDKNLIKDYEKIAYDAMNDDGNFFTKYGTFFITGLKSTILISIIGVVLGAVLGAMIALMKISKILPLKWLASAYIEFLRGTPLLVQVFLVFFGTTAVLGLDISAFICGAIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLGYGQTMKSVIMPQAIKNILPALGNEFVTVIKESSIVSVIGVSEIMFNAQVVQGVSFDPFTPLLIAAVLYFILTFTLSRLMSFIEGRMRVSD
>NZ_CP020773.1|WP_085236434.1|311407_312139_-|amino-acid-ABC-transporter-ATP-binding-protein
MIKIKKLNKSFGSTKVLTGIDMKIAKGEVVAIIGPSGSGKSTLLRCMNLLEVPTSGQVIFEGRDLTSKGTKVDELRQKMGMVFQNFNLFPHKKVIDNIMLAPQLLKKGDAQQLKTRALDLLDKVGLKEKAEAYPNQLSGGQKQRVAIARALAMNPDVLLFDEPTSALDPEVVGEVLTVMKSLAKEGMTMVVVTHEMDFAKNVSDRVIFMADGVVVEDGTPHEIFENPQHQRTQNFLKRVLNNV
>NZ_CP020773.1|WP_085238395.1|332101_333421_+|ISL3-family-transposase
MYNDISEMIGIKVSNLKITECLGIQTFKNVQSLFYKGVLTYQPKGCECCGIKNEQHTVIKNGFRSTRVYMGLILERPSYLVLKKQRFYCKACGQTFTAKTPYIEPRCTISNDVKLMVTRKLATVISEKDIANSVLVSPSTVHRYLKDLGEAVKTQPSDILPQHLSFDEFKSTNDVDSSMSFIYCDSITHDIIDILPDRRKFKLEEYFLRFSRKQREGVKSVSIDMYPPYMSLIQSLFPNADIILDRFHIVQAVNREINHSRVKTMNSFKTKEKPKYNKLKRYWKLLLKSPIELDRVHYHSFRLFNTWHSQYSLVQFLLTFDEEFQLTYEAGHHILETLRSNNIEQLEEALQRSKSLNISNGLKRVVNTLIKYIPYISNTIQNPHLTNGPIEGINNKIKLIKRVSYGYRNFYNFRNRILIISRLYVSEYKKRTKQQKIAT
>NZ_CP020773.1|WP_085236449.1|333465_333924_-|peroxide-responsive-transcriptional-repressor-PerR
MTTELESHDHQLKESIASLREAGVRITPQRQAILNYLIKADTHPTADEIYQSLSPDFPNISVATIYNNLKVFKKTGIVKELTYGDASSRFDFETHNHYHVICEKCGKIVDFHYPLLHEVEQLAQHVTDFDVTHHRMEIYGVCQSCKEAEKEA
>NZ_CP020773.1|WP_085236452.1|334005_334956_-|hydroxyacid-dehydrogenase
MLVVSLMRLDEEETRLKEAFPEVDFKFYKHPSELPVDLQEQMDVVISYHPEVDAQFIKQSPRLKWIAWYATGVNSLPFETLKEKGIQLTNAGGVHAQQLTEFLFAYILDDYKALKEAYAEQQQKVYNNKRITASLNEQRILFLGTGRIPQRSAQVAQTFGMKTIGLNTTGHPADYFDETYPLSERQQHFAQADIVVNLLPETEETYHLLSEIDFEAMNDHTLFVNLGRGTITPESVIIDSLKSKKIRKAYLDVFEKEPLDEQSELYTLDNVYMTPHISGNRSDNKKRATDIFSRNLTSFLKDNKLVENVVNANKGY
>NZ_CP020773.1|WP_085236454.1|334962_335421_-|thioredoxin-dependent-thiol-peroxidase
MLKKGDVFPEFKLQNQNGSEITKASLKGKKAILYFYPRDNTPTCTTEACDFRDHISYFNELNVQVYGISADSMRKHQNFIEKHQLNFDLLVDEDYELSKAVGVYQLKKSFGKESMGIVRTTFVIDEEGQIIEVIEKVKVKEQMAQLKEILKG
>NZ_CP020773.1|WP_085236456.1|335503_336790_+|glutamate-1-semialdehyde-2,1-aminomutase
MNFSQSEQLQKLSNEYILGGVNSPSRSYKAVGGGAPVVMKSGKGAYLYDVDGNQYIDYLQAYGPIITGHAHPHITQAIQEQAAQGVLFGTPTELEIDFARKLRHAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRDKIIKFAGCYHGHSDLVLVAAGSGPSQLGSPDSAGVPKSVAQEVITVPFNHIEAFKEAMSYWGDQVAAVLVEPIVGNFGMVEPVPGFLEEVNRITHEYGGLVIYDEVITAFRFHYGAAQDLLGVYPDLTAFGKIIGGGLPIGGYGGRQEIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQPGVYEKLDQLGARLEAGLQDAIAQYQIKATINRVRGALTLYFTDEKVTHYNQADASDSALFAKFFKLMLHQGINLAPSKYEAWFLTTEHTIADIDKTIEAVRYAFSQL
>NZ_CP020773.1|WP_085236458.1|336883_337978_+|aromatic-acid-exporter-family-protein
MKLGARILKTGIAIVLAVSIASLLPNDAGTVTVAGIAAVVAMQPSVYRTFKTIVDQFQGNIIGALLAVSMVTVFGNNVLIMGATVILLIALLFRMKIAHVATLATVTALVIMGQHNGSFYASAFYRFSLVMIGVISSFIVNLTFLPPKFETKIYYNSLNISTDIFKWFNLVLNDATEFNYVKQDLENLRQRIVKLEQFLEFYKEERVFTKKQIFAQTRKKILFKEIVLATRDAYDVLRRMNRYQNDLVHLNQTLRFQIKLEIDELTQFHEQILISITKKAKFDVTHDQHFVPHPLKKDIITAFREEVVNDSHPDGFSYANIMHIISALEEYRYNLEHLDRLRVSYFKYHANDPEIDIVEEDFDL
>NZ_CP020773.1|WP_085236460.1|338115_339708_-|FMN-binding-glutamate-synthase-family-protein
MTFLTVLQLIVTILLVGFLIFVLIAVIGFLIFDKRQKQHSVLRNYPVLAHVRYFLEQIGPELRQYLFLNDNEDKPFSRMEYQNIVLAGKYNSRGTSFGTLKHYDSGFFINNAMFPTQKDALIVDQSQLLSTFIYHIKNETLINRFEKIQAKKIKPFYLAPEHYVKIGHDIQHPFYVKRLVGQSGMSYGALGKNAITALSKGLGKANTWMNTGEGGLSDHHLAGDVDIIFQIGPGLFGVRDETGQFDTTLFKELAARPQVKAFEIKLAQGAKTRGGHIEGKKVTEEIAKIRHIKPYETVDSPNRFEMISNAEDLLKWIDSMREISQKPVGFKMVLGRQDDFIRLLDAMKSLNIYPDFITIDGGEGGTGATFQELQDGVGLPLFTALPIIDGLLKAYGLRDRVKIFASGKLVTPDKIAIALALGADLVNIARGMMISVGCIMSRQCHKNTCPVGVATTDPKKEEALVVDEKQYRVMNYITSLHEGLFNIAAAVGVKSPTEIGPEHVTMKHKDGQIESIHDYQLKLIQSSLKV
>NZ_CP020773.1|WP_085236462.1|339961_341698_-|ABC-transporter-ATP-binding-protein
MIKRYLEFVKPYKWLIFGTIVVGILKFGIPLLIPLLIKFVIDDVINNAALTVDDKLMRLGIAMLVAAFIFVIVRPPIEFFRQYMAQWTSNKILYDIRKKLYDHLQALSSKFYANHKSGEVISRVINDVEQTKDFIMTGLMNIWLDCITIIIALSVMFVLDVQLTLSAVIVLPFYILTVYFFFGRLRALTRQRSQKLAEVQGFLHERVNGMAVIKSFAIEDNEAKNFDKRNINFLNSAFKHTRWNAYSFSAINTVTDIGPLIVIGYGTYLAITGSVTVGTLAAFVSYLEQLYGPLRRLVSSFTTLTQSFASMDRVFQLIDEPYDIKNTTGAQPIPIQQGHIQIKNVSFKYQSDAHDILKQLNLDIHRGETVAFVGMSGGGKSTLINLIPRFYDVTEGQILIDGHDIKAFDLGSLRRQIGMVQQDNILFSDTVRENILLGRPDATFEEVVEAAQLANAHEFIMSLPKGYETEVGERGVKLSGGQKQRLAIARIFLNDPPILILDEATSALDLESEAIIQDALDTLSHDRTTIIVAHRLSTITHADQIVVIENGQIVEQGSHDVLMQQKGAYHRLYSIQNV
>NZ_CP020773.1|WP_085236464.1|342034_342577_-|DUF402-domain-containing-protein
MVKSCIPREGEAIKIQSYKHDGNIHRVWSETTILKGTADVVIGGNDHTLVTESDGRTWVTREPAIVYFHSEYWFNVICMFREDGVYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPKDIDMILRRNVDILQQWIEQKKGPFAPDFIKVWRQRFQKLSKG
>NZ_CP020773.1|WP_085236467.1|342638_343691_-|A/G-specific-adenine-glycosylase
MLNETTFKSHLLTWFEAAQRQMPWRETKNPYYIWISEVMLQQTQVDTVRDYYLRFIEAYPTIHDLAKAKEEEVLKLWEGLGYYSRARHFHTAAKEVVAQHQGKIPQQSDTFLALKGVGPYTQAAVMSIAFDLPLATVDGNVFRVWSRLNDDTRDTALQSTRKAYEQELVPYVTEQAGDFNQAMMELGALVCTPKAPLCLFCPVQIHCESFQQGTVLERPVKTKKLKKKTVVFDVYVIQNHSGDYLIEQRTVSLLKGMWQFPMFENETSYEDKLNVLGIKQLNTIQENVVQMKHQFTHLTWILNVHLAKIDPSEEADIVKGRQWMAAEDKTQYSFPVSMTQIFNAVRQADN

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Crispr_ID: NZ_CP020773_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020773_2

588031-588524

Unclear

Consensus_repeat	Method
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	CRISPRCasFinder
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	CRT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	PILER-CR

7 spacers

cas2,cas1

The CRISPR arrays of NZ_CP020773_2

>merge|NZ_CP020773|2|588031-588524|CRISPRCasFinder,CRT,PILER-CR
AAATTCTAGACTTCTAAAAAATCATAGTACTAAAACAATGCTTCCACATTGATTAAATTGTTTTCGTTTTACTTCTTTCTAAAAAATCATAGTACTAAAACTAAAGATAAGGAAGCAATTAAATTATACATGTTTTACTTCTTTCTAAAAAATCATAGTACTAAAACACTTCGATTTTGTGAGGATACTCATTCATTGTTTTACTTCTTTCTAAAAAATCATAGTACTAAAACGAACATTATCTGTGGGATATTTACGAACCAGTTTTACTTCTTTCTAAAAAATCATAGTACTAAAACATCCATATTCACCTGCATCAAGTTTTTGAGTTTTACTTCTTTCTAAAAAATCATAGTACTAAAACTTTAACACGCAAATTATCGAATCAGAAGCGTTTTACTTCTTTCTAAAAAATCATAGTACTAAAACACATCGACAATGAGACGTCCCGTATCTTTGTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC

>NZ_CP020773|2|2|588031-588524|CRISPRCasFinder
AAATTCTAGACTTCTAAAAAATCATAGTACTAAAAC	AATGCTTCCACATTGATTAAATTGTTTTC
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	TAAAGATAAGGAAGCAATTAAATTATACAT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ACTTCGATTTTGTGAGGATACTCATTCATT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	GAACATTATCTGTGGGATATTTACGAACCA
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ATCCATATTCACCTGCATCAAGTTTTTGA
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	TTTAACACGCAAATTATCGAATCAGAAGC
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ACATCGACAATGAGACGTCCCGTATCTTT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC

>NZ_CP020773|2|1|588031-588524|CRT
AAATTCTAGACTTCTAAAAAATCATAGTACTAAAAC	AATGCTTCCACATTGATTAAATTGTTTTC
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	TAAAGATAAGGAAGCAATTAAATTATACAT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ACTTCGATTTTGTGAGGATACTCATTCATT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	GAACATTATCTGTGGGATATTTACGAACCA
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ATCCATATTCACCTGCATCAAGTTTTTGA
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	TTTAACACGCAAATTATCGAATCAGAAGC
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ACATCGACAATGAGACGTCCCGTATCTTT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC

>NZ_CP020773|2|1|588096-588524|PILER-CR
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	TAAAGATAAGGAAGCAATTAAATTATACAT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ACTTCGATTTTGTGAGGATACTCATTCATT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	GAACATTATCTGTGGGATATTTACGAACCA
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ATCCATATTCACCTGCATCAAGTTTTTGA
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	TTTAACACGCAAATTATCGAATCAGAAGC
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC	ACATCGACAATGAGACGTCCCGTATCTTT
GTTTTACTTCTTTCTAAAAAATCATAGTACTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020773.1\|WP_085236831.1\|598283_598598_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|129903
NZ_CP020773.1\|WP_085236823.1\|584849_585335_-\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|377129
NZ_CP020773.1\|WP_085236821.1\|581291_583253_+\|sialic-acid-synthase	unknown	unknown	gnl\|CDD\|226715
NZ_CP020773.1\|WP_085236834.1\|600192_600621_-\|galactose-6-phosphate-isomerase-subunit-LacA	unknown	unknown	gnl\|CDD\|181505
NZ_CP020773.1\|WP_085236835.1\|600813_601566_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP020773.1\|WP_085236817.1\|576112_577111_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|226959
NZ_CP020773.1\|WP_085236828.1\|589831_590707_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP020773.1\|WP_085236833.1\|599662_600178_-\|galactose-6-phosphate-isomerase-subunit-LacB	unknown	unknown	gnl\|CDD\|181506
NZ_CP020773.1\|WP_085236829.1\|595126_596530_-\|6-phospho-beta-galactosidase	unknown	unknown	gnl\|CDD\|184102
NZ_CP020773.1\|WP_085236824.1\|585390_585636_-\|DUF2273-domain-containing-protein	unknown	unknown	gnl\|CDD\|227834
NZ_CP020773.1\|WP_085236832.1\|598621_599593_-\|tagatose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|183502
NZ_CP020773.1\|WP_085238405.1\|589497_589791_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP020773.1\|WP_085236820.1\|580000_581191_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP020773.1\|WP_085236819.1\|578259_580023_-\|siderophore-synthetase	unknown	unknown	gnl\|CDD\|226715
NZ_CP020773.1\|WP_085236818.1\|577179_578256_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143490
NZ_CP020773.1\|WP_085236830.1\|596547_598278_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273055
NZ_CP020773.1\|WP_085236822.1\|583396_584557_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP020773.1\|WP_085236826.1\|586528_587539_-\|zinc-binding-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176214
NZ_CP020773.1\|WP_103322043.1\|585648_586197_-\|alkaline-shock-response-membrane-anchor-protein-AmaP	unknown	unknown	gnl\|CDD\|380217
NZ_CP020773.1\|WP_085236827.1\|588652_589501_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP020773.1\|WP_085236823.1\|584849_585335_-\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	9.26336e-36
NZ_CP020773.1\|WP_085236821.1\|581291_583253_+\|sialic-acid-synthase	gnl\|CDD\|226715	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism].	1.20164e-92
NZ_CP020773.1\|WP_085236834.1\|600192_600621_-\|galactose-6-phosphate-isomerase-subunit-LacA	gnl\|CDD\|181505	PRK08621, PRK08621, galactose-6-phosphate isomerase subunit LacA; Reviewed.	8.48262e-79
NZ_CP020773.1\|WP_085236835.1\|600813_601566_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	1.96032e-77
NZ_CP020773.1\|WP_085236817.1\|576112_577111_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|226959	COG4594, FecB, ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism].	1.26894e-116
NZ_CP020773.1\|WP_085236828.1\|589831_590707_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	3.06224e-101
NZ_CP020773.1\|WP_085236833.1\|599662_600178_-\|galactose-6-phosphate-isomerase-subunit-LacB	gnl\|CDD\|181506	PRK08622, PRK08622, galactose-6-phosphate isomerase subunit LacB; Reviewed.	3.06809e-121
NZ_CP020773.1\|WP_085236829.1\|595126_596530_-\|6-phospho-beta-galactosidase	gnl\|CDD\|184102	PRK13511, PRK13511, 6-phospho-beta-galactosidase; Provisional.	0
NZ_CP020773.1\|WP_085236824.1\|585390_585636_-\|DUF2273-domain-containing-protein	gnl\|CDD\|227834	COG5547, COG5547, Small integral membrane protein [Function unknown].	6.81397e-17
NZ_CP020773.1\|WP_085236832.1\|598621_599593_-\|tagatose-bisphosphate-aldolase	gnl\|CDD\|183502	PRK12399, PRK12399, tagatose 1,6-diphosphate aldolase; Reviewed.	0
NZ_CP020773.1\|WP_085236831.1\|598283_598598_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|129903	TIGR00823, PTS_system_lactose-specific_IIA_component, phosphotransferase system enzyme II, lactose-specific, factor III. The PTS Lactose-N,N?-Diacetylchitobiose-b-glucoside (Lac) Family (TC 4.A.3)Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains.The Lac family includes several sequenced lactose (b-galactoside) permeases of Gram-positive bacteria as well as the E. coli N,N?-diacetylchitobiose (Chb)permease which can transport aromatic b-glucosides and cellobiose as well as the chitin disaccharide, Chb, but only Chb induces expression of the chboperon. While the Lac permeases consist of two polypeptide chains (IIA and IICB), the Chb permease of E. coli consists of three (IIA, IIB and IIC). In B. subtilis, a PTS permease similar to the Chb permease of E. coli is believed to transport lichenan (a b-1,3;1,4 glucan) degradation products, oligosaccharides of 2-4 glucose units. This model is specific for the IIA subunit of the Lac PTS family. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	4.79848e-43
NZ_CP020773.1\|WP_085238405.1\|589497_589791_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.86503e-23
NZ_CP020773.1\|WP_085236820.1\|580000_581191_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.30922e-54
NZ_CP020773.1\|WP_085236819.1\|578259_580023_-\|siderophore-synthetase	gnl\|CDD\|226715	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism].	1.87879e-77
NZ_CP020773.1\|WP_085236818.1\|577179_578256_-\|alanine-racemase	gnl\|CDD\|143490	cd06815, PLPDE_III_AR_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1. This subfamily is composed of uncharacterized bacterial proteins with similarity to bacterial alanine racemases (AR), which are fold type III PLP-dependent enzymes containing an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. It catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. Members of this subfamily may act as PLP-dependent enzymes.	1.85173e-110
NZ_CP020773.1\|WP_085236830.1\|596547_598278_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273055	TIGR00394, lac_pts_IIC, phosphotransferase system, lactose specific, IIC component. This family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	0
NZ_CP020773.1\|WP_085236822.1\|583396_584557_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	8.24341e-73
NZ_CP020773.1\|WP_085236826.1\|586528_587539_-\|zinc-binding-alcohol-dehydrogenase-family-protein	gnl\|CDD\|176214	cd08252, AL_MDR, Arginate lyase and other MDR family members. This group contains a structure identified as an arginate lyase. Other members are identified quinone reductases, alginate lyases, and other proteins related to the zinc-dependent dehydrogenases/reductases. QOR catalyzes the conversion of a quinone and NAD(P)H to a hydroquinone and NAD(P+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.6767e-159
NZ_CP020773.1\|WP_103322043.1\|585648_586197_-\|alkaline-shock-response-membrane-anchor-protein-AmaP	gnl\|CDD\|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	3.7964e-34

>NZ_CP020773.1|WP_085236826.1|586528_587539_-|zinc-binding-alcohol-dehydrogenase-family-protein
MKTILARQPFQLSEGLLFEAVTREMPQPDAHELLVKVYASGVNPVDTKMRQAPLNQASRVLGFDAAGVVVAVGDQVSDFTPGDRVYYSGSNQRDGSNQTYQLVHEHYVAKMPDRLSFTEAAALPLTAITAYETLFDCFGIATTPSDNQGKTLLIINGAGGVGSIATQIAKAYGLTVITTASRPETRAWSEKMGADVVLNHRHSLIDQFETQSLARPDYIFCTYDTDGYYDTMIELVKPRGRIATIVAFQEKQDLNALKAKSITLTHEFMFARAMYGIDVHMYRHYLEDVTEKVESGQYQTTLNTVLKGLTPENIFRAHEMMEAQSHIGKLVIEVAE
>NZ_CP020773.1|WP_103322043.1|585648_586197_-|alkaline-shock-response-membrane-anchor-protein-AmaP
MKMTRLKNFILGLLIVVIVGFLLFMYVDYQPIKQYQNYFYQFNWFDPLLIGLAALLILIGLILFFRAFKPTYRKPGLYKDYSDGHIYISRKSIENTVYDTLRQYENVRQPNVVSKLYNKKNDSFIDISTDFFVPSESTHIQSLVEEIRADIKESVERFSELHVKSVKVNVRDQRKDNGPRVI
>NZ_CP020773.1|WP_085236824.1|585390_585636_-|DUF2273-domain-containing-protein
MSNEKQNGQGEREAVEQFVQTLKHYKWRLIGFFFFLVIAILFLTLGFWKTILIIVLCLIGIGLGYIKDRTQDFLNLLNRLS
>NZ_CP020773.1|WP_085236823.1|584849_585335_-|Asp23/Gls24-family-envelope-stress-response-protein
MAVDNNKAKESYNKETGVNEKERQHENQGQQFSNTLTFSDEVVEKIAGIAAREVRGILDMKGGFVDTISGSFSSGNNVTQGVSAEVGEKQAAIDLKVILEYGESAPKIFRKVTELIKEQVKHITGLDVVEVNMHVEDVMTRKEWQQKHEKNRNQNDDKGLQ
>NZ_CP020773.1|WP_085236822.1|583396_584557_+|MFS-transporter
MTIMRTLTFMLSIFIVGMVEMVVAGIMSLMSADLNISEAWIGQLVTIYAFTFALTGPILVKMTEKYSPKNVLLLAVAFFVLGNLMIALSPNFIVLIVGRVISSAAAALIVVKILAITVILTQPAHRGKMLGIVYTGFSASNVFGVPLGTLIGDWVGWRFTFGLIIAVGLLAGLLLTIYLPRQVMPSYETHSKTQSRMVHQREIIKLLATTFVLLTANSVAYIYINPLILSGGHTITFVSLALFIIGIAGMCGTTLGGFFTDLFSFKTWLIISTFVFVVMMLLLNSLWGTSLALLIALFIWQIIQWSTNPAVQTGLIAQVEGDHSQVMSWNMSALNAGIGFGALLGGVIVAHTHLYATIQFAAGIGFISFLIVLSLKSQHGKSHNIS
>NZ_CP020773.1|WP_085236821.1|581291_583253_+|sialic-acid-synthase
METEQNHLEMAVIDFTKDEKETYQTLLSQDTGWATQFKQRCLLGRDKITARLVASLYRENLVNGYTHSDLKRAEQLQNSPITSGELLCIHFKRCQKTLYAPVVSHHAFNRIDVQGPFYWETQSGVFQRILHPNEVLDMMIEEDPQYQGEAANQFRDDLENSATHMTLALSYQAQHPLNDVASLLQYIQSQSDSYLTSEQLVIEGHPIHPGAKLRKGMSAKETIAYSSEYQQAIPMQFILIHKSMTRTMAQAETYLEVVYPAFKGLKNIAQHALPPTSTLDEYVPFIVHPWQYEHVILKDYHPAFESQMIVPLDYSIDYYAGLSFRTLMPKKPTLTPHIKLSTNVHITGEIRTLSEQTTYNGPLMTRILTHITQHDPLLDHVPTSPVPEIAGAHYYNDQNGSTEIQERLSEQLGTLFRQNIYALIEPDLLPCITSSLVVTHPQTGRPLIVDLVERYQTHNNITGTVDACAEWFTTYANALISYVVPLLVKYGIALEAHLQNAIAVFHPHTGQFSHMLIRDFEGLRIDATQLAKMGYHTDHFHEKSRILTTSQTSVFNKAFYSTIQNHLGEMVASLARFYDHPEIEAALWHIVRQQMVQIFQRMKADGDIASERIDAMYQTFFNETIDYKCVTTMRLLDEAHEYTYIKVKNPLAR
>NZ_CP020773.1|WP_085236820.1|580000_581191_-|MFS-transporter
MAKWFFPSTFLLFLGNWIGQIALNWYAYQLNQNAMDLALINFFRLAPIFVLSLWAGSIADRYRRSTLIKLTVTSSMVITSVLTICVLIVHQIPMPYLYIYACLRGCMSAIETPVRQVVLPDISEKLSISKAVSYHSFLLNVCRSIGPAVAGFLIAVWGVPVAFIAQSLCYVLALCLCLPLKIAKTQAVVSKQLSLSVAWQYFKIHVQGRQIFITSFLIMAMGYSYTTMLPILTDEIYPNSASVFGTAMTMSAIGGILATLAVPYILQKLSSDHAYYLSSLCFGIALLLIYPFGQIGLFLMIFFVGLFGQFARTTNRIYFQNDIPEVRRGKILSVVMMDRGMIPLGAMLLSYLTQWLGITTTFLWMGGTTTLIAILGYLAKFKINGGKTIHGNHSSS
>NZ_CP020773.1|WP_085236819.1|578259_580023_-|siderophore-synthetase
MAITRHLNADRNIQYRILSACVKEQLFPNGTSVQFQQGQLIIQYHQHLLSVRCETKSAFAQFELAGMIHYCVAQQEEEIKSVEQLIQVLSQHFKISFHEQLVEELYHSRLGLTLSYEQLQQRERLTRHALKFSRMPDKLNFIAWLNHMADETSFSVLGYSEGMIWEGHPSHPLTKTKLPLTVDEIRQYAPEFMKVIPLKILLVRQSLLKSTTMTGEDDFVLRKMFPDIESQLRQWMQTYEGTLDDYRVMLVHPWQYSHVIVSRFQQLITQHDVIPTPFTIDSKATLSFRTMQLLDYPYHVKLPINVQATSAVRTVSTVTTIDGPKLSYQLQKMLNIYPTLSVASEPYGAHIDVEPDLARQFAMIVRHSPEEHKQTHLQLVTGVLTQLNPVDGQVVIESLIEYLFGELNQQTISKFMKQFLNALIPPLIGYIQHYGIALEAHQQNTILQINREDHTLSFIVRDLGGSRIDLDTLKRAIPDFEVTNESLIAENIEAVIAKFQHAVIQNQLGTLIHHFHHAHQIEEAELYQIVADVVAQSIDPSQPHAEVLQRILFGPTVTVKALLNMRMAQKVKQYVQIEIENPLEREL
>NZ_CP020773.1|WP_085236818.1|577179_578256_-|alanine-racemase
MPQLHINLSKIKYNAMILQQMLAEKDVRMVPVTKCTGGDVKIRQQLFDMGFPILAESRLMAMASEETAHRSKNMMIKGALPDEIDAVVKLSQISIQTEIETIRALNEKAIEQGVKHHIYLMVDWKDGREGALTYEVVNLVKEIVQLKGIYLKGLSFNFMCFRQIPPTEEDIVYINYFIESVERDTGVRFNTISGGNSSMLMLAMYTDLGRINELRIGEVLFRGYETAYEMRLPYLYDDAMMLSGRVLEIKPRLNLDQRQSYMQALVDIGQLDTDIEGITAVDQQLHIVGHSSDILMVNLGLTDYYQIGDKIEFRINYSALAQSMHMAHIPKRYYEDQGIEALINGFVEIKKNRFIKQS
>NZ_CP020773.1|WP_085236817.1|576112_577111_-|ABC-transporter-substrate-binding-protein
MKTKKWYGLLTVIAIMLIVAACGKTNDSGQSDSKKQADGTKGVEIKHSGGTTKIDKEPKRVVALEYSFVDALTALGVKPVGIADDGKKKNIIEPLRDKVGDYKSVGARKQPNLEVISELKPDLIIADSNRHKGNYEQLSKIAPTILLPSLDADYKENIEAFKTIGKALSKEKEADKRLKAHEDKINQYKKEITMDKDKKVLPLVISQSGILAHSDKSYVGQFLRDLGFKEALTKEVADQLPEYLNAPYLNMNSEQLADVNPERMFVMVNGENDPEYLKVQKDPVWKEIDAVKNHRVHVVDRQTWSKFRGLISSEEIAKELAEISKKEKGNDK
>NZ_CP020773.1|WP_085236827.1|588652_589501_-|hypothetical-protein
MKLASDVTEVLDIDLHHTHVITFEDTQLCETFIQSFLSYLQKKPQKDEHYAHFITDGYETINVQKFHPIILNCGDRNILGQKVIEDQVLNHFENQIIYDEKTNKIFNEFEESLNIFKQSLGIYDDYYHVEIHDNVIKLKKLLKLLGYEFHYDLRDLDETRKRKAFIDLMRKKEKEEILVVLYPESYLGIKEIEDFLTMIKMYQLTTLVFTNHPSVIMSGDHAFLCKSNKTCHDLNLIKEELKLFMPEEMITSKMVHLIAYHEFIGDNLLELGQYFKFINQYE
>NZ_CP020773.1|WP_085238405.1|589497_589791_-|CRISPR-associated-endonuclease-Cas2
MFDLPVETSSEKRAYRKFVKFLTTEGYVRLQYSIYSKLVFNSTTLKYTLEKLKIVVPSKGLIQTLVVTENQFSNMKYIVGEPPKGHLGLSSERVIEL
>NZ_CP020773.1|WP_085236828.1|589831_590707_-|type-II-CRISPR-associated-endonuclease-Cas1
MSFRTVIVTKEAKLSLRMNQLIVNTGDLNYIPLNEILCLVIEHPNVSMTGHLINALSDRKIITILCNNRHLPNTLILPMYGHHRQVKQIKKQMNWSQERKNKLWQRLIKQKIRNQQQVLDTFFKQKNTENFDEYIEAVEPGDITNREGHAAKVYFNTVLQPGFTRGYDNAQNAALDYGYQVLLAIVARTIVSKGYLTEIGIKHKNEYNIYNLASDFMEIFRPIVDSIVLKFVKQEFGKEEKRVIIDLLNKKVKIDNKNYYFVNAVERYVDSLFLYLSTGDMEVIRIPTWTY
>NZ_CP020773.1|WP_085236829.1|595126_596530_-|6-phospho-beta-galactosidase
MKKLPTDFIFGGATAAYQAEGATNIDGKGRVAWDTYLEENYWYTAEPASDFYNRYPIDLELCEKFGVNGIRISIAWSRIFPTGYGEVNQKGVDYYHALFKTCLKHHVEPFVTLHHFDTPETLHSDGDFLNRANIQHFVDYAAFCFKEFSEVKYWTTFNEIGPIGDGQYLVGKFPPGIQYDFEKVFQSHHNMMVAHAKAVVLYKEQGYQGEIGVVHALPTKYPYDSTNAEDVRAAELEDIIHNRFILDATYLGRYSEQTMAGVNHILSVNGGTLDLRDEDFEILDAAKDLNDFLGINYYMSDWMRGFEGETEITHNSKGSKGGSKYQLKGVGQREYDVDVPRTDWDWMIYPQGLYDQMMRVKNDYPNYKKIYITENGLGYKDEFVDETVYDDARIDYVKKHLEVIADAIEDGVNVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQARYPKKSAYWYKKLAETQVIE
>NZ_CP020773.1|WP_085236830.1|596547_598278_-|PTS-transporter-subunit-EIIC
MNRLIEFIEKGKPFFEKLSRNMYLRAIRDGFISAMPIILFSSIFLLIAYVPNIFGFTWSKHAEAIIMKPYGYTMGIVGLLVAGTTAKALTDSYNRKLASTNQINFISTMLASICGFLFLASNPLEAGGFANAFMGTKGLLTAFLSAFVTVIIYHICVKNNITIKMPKEVPPNISQVFKDLIPFGLVILVLYGLDLLSRAVVNTNVAEAIVKFFEPLFTAADGYVGITIIFGAFALFWFVGIHGPSIVEPAIAAITYANIETNFKLLQAGEHADKILTPGTQMFIVTMGGTGATLIVPFMFMWLSKSKRNKAIGRASVVPTFFGVNEPILFGAPIVLNPVFFVPFILAPIINVWIFKFFVDVLGMNSFSVVLPWTTPGPLGIVMGTGFELWSFVLAITLIVVDVIIYYPFFKVYDEQILEEELKGNHDSDGLRSKVAENFNTAKADAILASSTGHVATESHSDTTSTTSPDITKQTNVLVLCAGGGTSGLLANALNQAAAEYQQPVTAAAGSYGAHMDIMKEYDLIILAPQVASNYEDIKQDTDRLGIKLAKTQGAEYIKLTRDGEGALQFVKDQFN
>NZ_CP020773.1|WP_085236831.1|598283_598598_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MNREEVAMLGFEIVAYAGDARSKFLEALTAAREGDFEKAEQLIEAGNQCIIEAHHAQTSLLQKEAAGDDIAYSVTMMHGQDHLMTTILLKDLLSHMLTLYKRGS
>NZ_CP020773.1|WP_085236832.1|598621_599593_-|tagatose-bisphosphate-aldolase
MSTKEELLTQLSDDKGIISALAFDQRGALKRMMAQYQTEEPQVKDMERLKQLVSEELTPYASAILLDPEYGLPATTVRHDSTGLLLAYEKTGYDVNAKGRLPDCLVDWSAKRIKEAGAQAVKFLLYYDVDDEDAINNQKEAYIERIGSECKAEDIPFFLEILAYDDAIADNKSAEYAKVKPRKVIEAMRVFSNERFGVDVLKVEVPVDMNYVEGFAAGEVVYTREEAAQYFKQQDEATALPYIYLSAGVSAKLFQETLRFAHDSDAHFNGVLCGRATWAGAVKAYIEQGEAAAREWLRTEGKANISELNKVLEETAVSYKAGL
>NZ_CP020773.1|WP_085236833.1|599662_600178_-|galactose-6-phosphate-isomerase-subunit-LacB
MKIAIGSDHIVTDTKMEVSQFLKSLGHEVIDCGTYDFTRTHYPIYGKKVGEAVTRGEADLGVCICGTGVGINNAVNKVPGIRSALVRDMSSALYAKEQLNANVIGFGGKIVGDLLLCDIVEAFINAEYQPTEENQKLIEKISQVESVNAHQTDDDFFDEFLEKWDKGEYKD
>NZ_CP020773.1|WP_085236834.1|600192_600621_-|galactose-6-phosphate-isomerase-subunit-LacA
MKVIIGADQYGAHLKAHIKTFLLNKQYEVVDVTSDDLVDFVDVTVAVAHKVQEDDNNLGIVIDEFGAGSFMVATKIKGMIAAEVSDERSAYMTRSHNNAKMITLGAALVGETLAENIVKGFIEGHYDGGRHQIRVDMLNKMG
>NZ_CP020773.1|WP_085236835.1|600813_601566_-|DeoR/GlpR-transcriptional-regulator
MNKYERLDEIARRVNEKGTIRITDIVEDLNVSDMTVRRDLIELEEQGILTKIHGGARSNQAFQYKEMSHHEKHTQKSKEKYEIAKKAAELIEDGNIIFLGPGTTVEMLAKEIENKRLSVVTNCLPVFQILQHKRSEQFSVYLIGGSQRKVTESFVGEMANTLLEKMRFSKIFFSANGIKGNEVMTSSYEEAYTQKLAISHSNEKYILADDSKIGKEDFVSFCELKNLTAIVTNRLNSEQMKAVQQYIEVI

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Crispr_ID: NZ_CP020773_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020773_3

1522665-1523230

TypeII

Consensus_repeat	Method
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	PILER-CR
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CRISPRCasFinder
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CRT

8 spacers

cas9,cas1,cas2

The CRISPR arrays of NZ_CP020773_3

>merge|NZ_CP020773|3|1522665-1523230|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACTCAGCTTGTGCATCTTCTTTTAATTGTTTAGTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACATTCGTTATCATTCGGAAAGATAAAACCGAGTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACAAAAAAGTTTTATCAATCCGCAGCTTAGTTGTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACACAAAGTGTATGCACTGTGCTATACTTAATGTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACAGGAGTTAGAGAATACTTTCGACAACTGGCGTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACACTCCACGCACCTGAGGGGCTTTCGTCTCTGTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACATAGTGATGTTGGCGAGCCTAAATTAATTTGTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACAATAATCAAAACTCGATAAAAAAACTTTAAAGTTTTAGTACTCTTTTATTTTAGGTATAAATGATACA

>NZ_CP020773|3|2|1522665-1523230|PILER-CR
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACT	CAGCTTGTGCATCTTCTTTTAATTGTTTA
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	TTCGTTATCATTCGGAAAGATAAAACCGA
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	AAAAAGTTTTATCAATCCGCAGCTTAGTT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CAAAGTGTATGCACTGTGCTATACTTAAT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	GGAGTTAGAGAATACTTTCGACAACTGGC
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CTCCACGCACCTGAGGGGCTTTCGTCTCT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	TAGTGATGTTGGCGAGCCTAAATTAATTT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	ATAATCAAAACTCGATAAAAAAACTTTAAA
GTTTTAGTACTCTTTTATTTTAGGTATAAATGATACA

>NZ_CP020773|3|3|1522665-1523230|CRISPRCasFinder
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACT	CAGCTTGTGCATCTTCTTTTAATTGTTTA
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	TTCGTTATCATTCGGAAAGATAAAACCGA
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	AAAAAGTTTTATCAATCCGCAGCTTAGTT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CAAAGTGTATGCACTGTGCTATACTTAAT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	GGAGTTAGAGAATACTTTCGACAACTGGC
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CTCCACGCACCTGAGGGGCTTTCGTCTCT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	TAGTGATGTTGGCGAGCCTAAATTAATTT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	ATAATCAAAACTCGATAAAAAAACTTTAAA
GTTTTAGTACTCTTTTATTTTAGGTATAAATGATACA

>NZ_CP020773|3|2|1522665-1523230|CRT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACT	CAGCTTGTGCATCTTCTTTTAATTGTTTA
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	TTCGTTATCATTCGGAAAGATAAAACCGA
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	AAAAAGTTTTATCAATCCGCAGCTTAGTT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CAAAGTGTATGCACTGTGCTATACTTAAT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	GGAGTTAGAGAATACTTTCGACAACTGGC
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	CTCCACGCACCTGAGGGGCTTTCGTCTCT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	TAGTGATGTTGGCGAGCCTAAATTAATTT
GTTTTAGTACTCTGTTATTTTAGGTATAAGTGATACA	ATAATCAAAACTCGATAAAAAAACTTTAAA
GTTTTAGTACTCTTTTATTTTAGGTATAAATGATACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020773.1\|WP_085237536.1\|1519540_1520953_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP020773.1\|WP_085237538.1\|1521950_1522511_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	unknown	unknown	gnl\|CDD\|237411
NZ_CP020773.1\|WP_085237537.1\|1521061_1521949_+\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	unknown	unknown	gnl\|CDD\|179769
NZ_CP020773.1\|WP_085237535.1\|1517550_1519485_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|224208
NZ_CP020773.1\|WP_085237539.1\|1523533_1526698_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
NZ_CP020773.1\|WP_085237547.1\|1532388_1534848_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_CP020773.1\|WP_085237533.1\|1501583_1502576_+\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NZ_CP020773.1\|WP_085237544.1\|1530372_1530834_+\|CtsR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226869
NZ_CP020773.1\|WP_085237530.1\|1499908_1500700_+\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|238380
NZ_CP020773.1\|WP_085237534.1\|1502598_1504086_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NZ_CP020773.1\|WP_085237540.1\|1526697_1527600_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP020773.1\|WP_085237543.1\|1529003_1530209_-\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_CP020773.1\|WP_085237541.1\|1527604_1527913_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP020773.1\|WP_085237548.1\|1535321_1536689_+\|DNA-repair-protein-RadA	unknown	unknown	gnl\|CDD\|236994
NZ_CP020773.1\|WP_085237531.1\|1500689_1501061_+\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|376737
NZ_CP020773.1\|WP_085237546.1\|1531368_1532373_+\|protein-arginine-kinase	unknown	unknown	gnl\|CDD\|234894
NZ_CP020773.1\|WP_085237542.1\|1527925_1528921_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020773.1\|WP_085237545.1\|1530848_1531379_+\|UvrB/UvrC-motif-containing-protein	unknown	unknown	gnl\|CDD\|226397
NZ_CP020773.1\|WP_085238400.1\|1516053_1517373_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP020773.1\|WP_085237532.1\|1501053_1501539_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|238269

Protein	Function_ID	Function_description	E-value
NZ_CP020773.1\|WP_085237536.1\|1519540_1520953_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.32331e-120
NZ_CP020773.1\|WP_085237538.1\|1521950_1522511_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	gnl\|CDD\|237411	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT.	4.71069e-111
NZ_CP020773.1\|WP_085237537.1\|1521061_1521949_+\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	gnl\|CDD\|179769	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS.	0
NZ_CP020773.1\|WP_085237535.1\|1517550_1519485_+\|FUSC-family-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	2.21751e-34
NZ_CP020773.1\|WP_085237539.1\|1523533_1526698_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	9.45928e-128
NZ_CP020773.1\|WP_085237547.1\|1532388_1534848_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP020773.1\|WP_085237533.1\|1501583_1502576_+\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	1.17256e-152
NZ_CP020773.1\|WP_085237544.1\|1530372_1530834_+\|CtsR-family-transcriptional-regulator	gnl\|CDD\|226869	COG4463, CtsR, Transcriptional repressor of class III stress genes [Transcription].	6.18158e-74
NZ_CP020773.1\|WP_085237530.1\|1499908_1500700_+\|dihydropteroate-synthase	gnl\|CDD\|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	1.07757e-113
NZ_CP020773.1\|WP_085237534.1\|1502598_1504086_+\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP020773.1\|WP_085237540.1\|1526697_1527600_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	3.70892e-94
NZ_CP020773.1\|WP_085237543.1\|1529003_1530209_-\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	2.59597e-153
NZ_CP020773.1\|WP_085237541.1\|1527604_1527913_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.36545e-30
NZ_CP020773.1\|WP_085237548.1\|1535321_1536689_+\|DNA-repair-protein-RadA	gnl\|CDD\|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP020773.1\|WP_085237531.1\|1500689_1501061_+\|dihydroneopterin-aldolase	gnl\|CDD\|376737	pfam02152, FolB, Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.	8.67456e-44
NZ_CP020773.1\|WP_085237546.1\|1531368_1532373_+\|protein-arginine-kinase	gnl\|CDD\|234894	PRK01059, PRK01059, ATP:guanido phosphotransferase; Provisional.	2.66271e-161
NZ_CP020773.1\|WP_085237545.1\|1530848_1531379_+\|UvrB/UvrC-motif-containing-protein	gnl\|CDD\|226397	COG3880, COG3880, Modulator of heat shock repressor CtsR, McsA [Signal transduction mechanisms].	3.81353e-34
NZ_CP020773.1\|WP_085238400.1\|1516053_1517373_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.18781e-62
NZ_CP020773.1\|WP_085237532.1\|1501053_1501539_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|238269	cd00483, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is HPPK which catalyzes pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin (HP). The functional enzyme is a monomer. Mammals lack many of the enzymes in the folate pathway including, HPPK.	8.33925e-73

>NZ_CP020773.1|WP_085237538.1|1521950_1522511_+|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT
MKIGVLALQGAVREHLRHIELAGHEGIPVKKVEQLEEIDGLIIPGGESTTLRRLMNLYGFKAALRESSLPMFGTCAGLIVLAKDIVGEEGYLQKLDITVERNSFGRQVDSFEAELDIKGIDQPIEGVFIRAPHIQSVESAVEILGEIDGKIIAVQQGRYLGVSFHPELTDDYRITQYFIEHVMTHA
>NZ_CP020773.1|WP_085237537.1|1521061_1521949_+|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS
MSKQIGSERVKRGMAEMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPSDIRAAGGVARACNPSIVEEVMNAVSIPVMAKCRIGHITEARVLEAMGVDYIDESEVLTPADEVFHLKKSDYTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNQEVKRITVMSDDELMTEAKNLGAPYEILKDIKAHGRLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEMFAKAIVQATTHYQDYKLIGELAKKLGTAMKGLDIQKLSLEERMQERGW
>NZ_CP020773.1|WP_085237536.1|1519540_1520953_-|PLP-dependent-aminotransferase-family-protein
MEMLMFHIDKSLAQPIYLQLYENIKQSIIKGQMHEGEKLPSKRQLSQYLSVSQTTVESAYAQLVDEGYIYSRAKSGFFVSDIDTLPFTQSVELESLSQVHPPFPNLTYAFKLGTIDQHHFPFEQFRKYAKEAFEELQFHLIEPGHKQGDLALRTQISHYLFHSRGVQSTPEQVIVASSTEQLLSMITDLLPDTKKFILEDPIYPQVHQVLKRKHIPYHFIPVEKEGIVIEDTSHQSHHIVYITPSHQFPTGVTMHLKNRMRLLKWATAQPHRFIIEDDYDSEFRYEGKPIPALQSLDQAGRVIYVSTFSKSISPTIRIAYAVLPKPLLSLYQRTTHIEGGTVPRHTQYMVARFMETNQFERHLNRMRKIYRQKRDIILTQLMRYPHVFDVSGEKTGMHFIITIKNGWSEKTCLERLTHFEIDMKPLSHYLYHNKQVQPPRFVLGFGGIPICELDQHIAQLIRCFTSNDFQ
>NZ_CP020773.1|WP_085237535.1|1517550_1519485_+|FUSC-family-protein
MRLFRYLKKVVYLDIHKIDLQRGFRQGLLMLIPLLYGWIFNDFSSALLATIGTFANIYVFKGPFTSRIRSVVFAAMGLVVTMMIGTLTAGIPLLFGIFLLFVAVIPYYVFNTLDIVGPASTFFIIGFSLSSVMPIEPSSFLIRGAIVGIGGILAILFVLIASILSKETPEFDAVSNEFRQLQQMVQHFNDQVKFNALTKTTVQTLIATSETLKASRALMKKKTLAVQRLTLLHHAAEGVYSELLELNAKGHRPIPAIIPEMMTDVVIRVTDQTQQKTTWKKAISVSPEFDTLVELIFKIDEVLDSPQEQVEKHVRMQSPQYWNRLRYHLTPESMNFISAAKYTLIMGVAILVALLFNFERAYWIPLSAHTVLLGGTTVASIERAGARWIGTCVGIVIVIGFLLLEPHTAMIILALCFSGMVTETLIGANYTLAMIAITSQVVLLAGLAQGQLTLDIAIPRLLDTTVGILIAVIGILLIGRRLASKYLPEMMAQVTRMEAQIFHTIFSNTPYDNEMFIQRDRLKLKIRIENMEAMYRFAYGELLSNQKRTQYFYPAMFILEQMSFKLLQAMYDQQRPMISEEEMGQYLVTFENIAKLFEKGQRQEAIVMLPEMPRYAQLRRFLMQLQQIELYDYQNRRNPHLLKD
>NZ_CP020773.1|WP_085238400.1|1516053_1517373_+|ISL3-family-transposase
MYNDISEMIGIKVSNLKITECLGIQTFKNVQSLFYKGVLTYQPKGCECCGIKNEQHTVIKNGFRSTRVYMGLILERPSYLVLKKQRFYCKACGQTFTAKTPYIEPRCTISNDVKLMVTRKLATVISEKDIANSVLVSPSTVHRYLKDLGEAVKTQPSDILPQHLSFDEFKSTNDVDSSMSFIYCDSITHDIIDILPDRRKFKLEEYFLRFSRKQREGVKSVSIDMYPPYMSLIQSLFPNADIILDRFHIVQAVNREINHSRVKTMNSFKTKEKPKYNKLKRYWKLLLKSPIELDRVHYHSFRLFNTWHSQYSLVQFLLTFDEEFQLTYEAGHHILETLRSNNIEQLEEALQRSKSLNISNGLKRVINTLIKYIPYISNTIQNPHLTNGPIEGINNKIKLIKRVSYGYRNFYNFRNRILIISRLYVSEYKKRTKQQKIAT
>NZ_CP020773.1|WP_085237534.1|1502598_1504086_+|lysine--tRNA-ligase
MTEEMNDQMLVRRQKLQELRDLGIDPFGEKFVRTGNAEALKAEWDAYTKEELADKEAESHTVIAGRIMTKRGKGKAGFAHIKDLSGQIQIYVRKDQVGDDAFNIWSSADLGDIVGVEGVMFKTNTGELSVKAKAFKLLSKALRPLPDKHHGLQDIEQRYRQRYLDLITNEESTQTFINRSRILQEMRTYLNEKGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMALTEALVAHIARRVLGTTTVQYGDATIDLEPQWRRLHMVDAVKEVTGVDFYEVKSDEEAHELAKAHGIEVDGNMKYGHVLNEFFEQKVEETLIQPTFIYGHPIEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQRARFEAQLIEKEQGNDEAHEMDEDFIEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPYMRQK
>NZ_CP020773.1|WP_085237533.1|1501583_1502576_+|tRNA-dihydrouridine-synthase-DusB
MWKIGDVEIENRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILFNNPKTMKMLYIDENERPLSLQIFGGEKETLVEAAEYVDKNTTADIIDINMGCPVSKIIKCEAGARWLLDPNKIYEMVSAVTERVSKPVTCKMRIGWDENHIFAVENAKAAERAGAAAISLHGRTRVQMYEGKADWDIIRQVKEAVNIPVIGNGDVTSPELAEKMLRETGVDAVMIGREALGNPWMIYRTVHYLETGELIDELQIDEKIEIALLHLNRLVDLKGEKVGVMEMRKHASWYLKGVRGNGTARKALNQAETLAEMTEILTQFRDERMEKQKLEV
>NZ_CP020773.1|WP_085237532.1|1501053_1501539_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MIDAYLGLGSNIGDREAQLKQAVALLDAHDAIHVVSVSPVYETKPVGYTEQPDFLNLCVHIQTELPAHALLEVALKTEAELHRVRKERWGPRTMDIDILLYGDAMIEDEDLIVPHPRMTERAFVMIPLNDIATNVIEPHSGQTIQQLVPHDDTVVKYKETL
>NZ_CP020773.1|WP_085237531.1|1500689_1501061_+|dihydroneopterin-aldolase
MKDKIFLQGLEFYAYHGALAAENEIGQIFTVDVEMKVDLREAGKSDRVEDTVHYGEVYEDIKAIMHDAAVQLLEHLAERIAIRINSHYNRVMETKVRITKKNPPIPGHYEGVGVEIVRVSHHD
>NZ_CP020773.1|WP_085237530.1|1499908_1500700_+|dihydropteroate-synthase
MPQTQIMGILNVTPDSFSDGGQFNEVTKAVAHATQMVEQGAHIIDVGGVSTRPGHEEVTVEEELARVIPVVRALQHLNVTISVDTFRSEVAEAALEAGARMINDQWAGLYDPRIFEVVARYDAELILMHNGDGTRDMPVMDEMLVLLLKQATKAIRAGVAQSRIWLDPGIGFAKTREEEQEAMSRLDELVATGYKVLLATSRKRFIKWLLGGDNKIDERDEATAATTAYGIMKGVHGVRVHNVLMNARLARAMDALKGYEDER
>NZ_CP020773.1|WP_085237539.1|1523533_1526698_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MRNSYILGLDIGITSVGYGIIDRVTREVIDAGVRLFPEANVENNEGRRSKRGARRLKRRRIHRLNRIKQLLKNAGLLEGDVLPKSTNPYEIRVRGLRSPLTKDELVIALLHIAKRRGIHNINIVGDDEETDSTLSTTAQLKKNEKALKGQFVCELQLDRLANAHQVRGEKNRFKTEDIVKEVRALLQQQQNFHNIDNSFVEQYIALLESRRTYYEGPGEGSPYGWDGDIKKWYEMLMGYCTYFPEELRSVKYAYTADLFNALNDLNNLVITRDDNSKLTYAEKYHIIENVFKQKKVPTLKQIAKEIGVNESDIKGYRINKSEKPLFTSFKLYHDLKSVFSDPTKLEDIDLLDRIAVVLTMYQDAESMKAALNTFPEVFSEAEKEKLSALTGYAGTHRLSLKCMNLLIPDLWQTSLNQMELFVKLNLKPQKLDLSQCHQIPTQLVDEFILSPVVKRAFTQSIKVINAIIQKYGLPDDIIIELAREKNSADKRKFLNQLQKKNEKARHEINTLVAQYGQPNAKRLVEKITLHQQQEGKCLYSLKDIPLEQLLKQPYLYEVDHIIPRSVSFDNSMQNKVLVLAEENAKKGNQTPYQYLNSREASMTYPEFKQHILNLSKAKDRISKKKRNYLLEERDINKFDVQKDFINRNLVDTRYATRELASLLKAYFKTHELPVKVKTINGGFTHYLRKVWKFDKDRNKGYKHHAEDALIIANADFLFKNQTLNKIEAILNEPGREVESDTVKVQSEDNYQDLFENTKKAFAIKNFKDFKFSHRVDQKPNRQLVNDTLYSTREVNEDLYVVQTLKDIYSKDNKDVKRLFDKQPEKFLMFQHDPETFKKFELAMKQYAEEKNPLARYYEEQGYITKYAKKGDGPPVKSLKYIGKKVGKHLDVTGDYEDSNRKLVKLSLKSFRFDIYHTDKGYKMVPITYLDVQKKEKYYYIPTEKYEALKQEKGINQNAQFIGSFYYNDLIEFDGELYRVIGINNGDKNLVELDMVDIRYKEYCELNSITTTPRIVKTISPKTQSIEKYTTDILGNLYKAQPGKKPQFIFNKDED
>NZ_CP020773.1|WP_085237540.1|1526697_1527600_+|type-II-CRISPR-associated-endonuclease-Cas1
MAWRIVYVAEVNRLSLNLNSLKIVKGDDEYKIPLNDIFAIVIEDLTVSITARLLVELSDYNILVIFCNQKHLPECVMQPVSGHYRQYNQTRAQLSWDHARKEELWKWIVKKKINNQIECMKHCQIDNERIEKMYELYRSVQIFDKNNIEGQAAKYYFNSFFTNFNRDNEDLLENAVLNYGYAILNAAIGRTLVAKGLIPSLGIHHIGGRNHFNLASDLIEPFRPLVDLYLMKYPPESFMTKEYRVKLVNLLHARVEIDGKMQTVIRAIELMIQSVIDYFREGQTSLLMFPNLAKYAFYEL
>NZ_CP020773.1|WP_085237541.1|1527604_1527913_+|CRISPR-associated-endonuclease-Cas2
MRVILMFDLPVETKQQRRIYSKFRKRLLENGFLMMQYSIYVKSVINRDAATLSVNQIKQFLPREGHVRALMITEKQYEKMQILLGEEDKNSVILGENRTILF
>NZ_CP020773.1|WP_085237542.1|1527925_1528921_+|hypothetical-protein
MEKIVWELKSEGLHSIELNIENYTSIYNEFDTREEDILQTIYGYFQKRASNKAYVTIIDKADGEVIPSQRYQCWLVNHEFIEKEFELAQTSLLNKKIVRQLKENYEIESYLHTMNVLLEDLVQFVDHGLPIKPKPFDYKAFSKHLQFKFDDHVDYYRLINRLERMLPLIVEEMEQISNHRTLLIYTYPEANLSPKEQIQFRKCLESLNIPVITLTGSAHFLSRNLMGMNYIRRDRQLINMRWLNQLVWDAPMNYEMDEIMVSLKRFIHLYQDKLEMTPLISNHRLADIMLFDPIDIYVGFSFMRYAEQAFTTDMDWGVLPEPVSRYMQHLL
>NZ_CP020773.1|WP_085237543.1|1529003_1530209_-|NupC/NupG-family-nucleoside-CNT-transporter
MHILIGVIGIVVFLALALVASSDKKNVRWHYIGLMLVIQLILAFFLLKTDIGIKIVGGIAKGFEYLLKQAAVGVNFVFGGLLNDGAMSFFLSVLLPIVFISALIGILQYTKILPLIINVLGFLISKINGMGRLESYNAVAAAILGQSEVFISLKKQLPYITKQRLYTLTASAMSTVSASIIGAYFTLIDPKYVVTAVVLNLFGGFIIASIINPYKVNEEDDKLLIDTEKKQQSFFEMLGEYILDGFKVAVIVGAMLIGYIALISLLNGLIGGIISLVSGGTLDWNFQTLIGFIFAPLAFLTGIPWNDAVDAGSIMATKLLSNEFVAMTELGKVHGLTERSLGVVSVFLVSFANFSSIGIISGAIKSLHDEKGDIVARFGLKLLFGATLVSFISATIAGFFL
>NZ_CP020773.1|WP_085237544.1|1530372_1530834_+|CtsR-family-transcriptional-regulator
MHNMSDIIEQYIKQLFEEAQDDVVEIQRAHIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKVETKDQNNYIKRLIGLIGPALSQQQALYIIDGLLDNGLVTEREAKMIAAVVDRETLKMDVASRDIIRANILKRLLPVINYY
>NZ_CP020773.1|WP_085237545.1|1530848_1531379_+|UvrB/UvrC-motif-containing-protein
MKIDKRVLEKQHKDQHEHLNVRMYDQTGDESSDAQWHEGDDVEGTFVIQQILQHLAAKHGLSVDQVVYREQKRCPNCQMTLKDIAHVGKFGCHQCYQTFKEDVYDIVRRVQGGHIEHAGKCPKSAQHQRAIKKQLEAKRARLDQLVAQQAFEEAAVVRDEIQALERQSEVSRQDGE
>NZ_CP020773.1|WP_085237546.1|1531368_1532373_+|protein-arginine-kinase
MVNNLDQYMSHWMKKVNAQPVIMSSRIRLARNLENYVHPLMFSSEEEGHRVINEVQDVLTDLKVLRLDELDQLSKYKLVAKHLISPELTKQPAAAVLLSEDESISVMVNEEDHIRIQAMGNDLSLNELYQKASEIDDTLDQAVQVSYDEQLGYLTTCPTNVGTGMRASVMLHLPGLSIMKRMNRIAQTINRFGFTIRGIYGEGSQVYGHIYQVSNQMTLGKSEQEIIDALTELVNQIIHEELALRERLNAHNHMETLNRIYRSLGILKYGRLISVEEASYRLSDIKLGVDLGILDMENFRFNELMVAIQSPFLIDETDEQSIEAKRAEILRTYI
>NZ_CP020773.1|WP_085237547.1|1532388_1534848_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEEKVIEEVEKLIGHGQQQMGALHYTPRAKKVIELSMDEARKLQHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGSPEMSNKNTQGAKANNTPTLDGLARDLTVIAKDGTLDPVVGRNAEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKGKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIHQAGNVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKHIEKDAALERRFQPVQVAEPSVADTIEILKGLRDRYEAHHRINISDEAIVAAAKLSQRYVQDRFLPDKAIDLIDEASSKVRLKSHTTPTNLKEIEQQIEQVKKEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNNQGGEHTTLVAEDIAEVIAGWTGIPLTRLNETESDRLLKLEETLHERVIGQNDAVIAVSKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAEAMFGEEDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRRVDFRNTVIIMTSNVGAQELQDQRFAGFGGSSEGQDYETIRKTMMKELKNAFRPEFLNRVDDTIVFHKLNKEELKEIVTMMVGKLTQRLSEQNININVTEAAKDKIAEEGYDPEYGARPLIRAIQKTVEDNLSELILEGKELEGKNVTVDYDGESFQYDIHEREADEDKAVTEA
>NZ_CP020773.1|WP_085237548.1|1535321_1536689_+|DNA-repair-protein-RadA
MAKKKTIFECTACGYQSPKWMGKCPNCGAWNSMEESFEQKTTSPKHGVRSEKASTAKIQKLHDIKQELAPRIQTNSGELNRVLGGGIVEGSLVLIGGDPGIGKSTLLLQMCAALSQEKKVLYVTGEESLNQTKIRADRLDEDASQLNVFAETDLVVIHEAVKQLEPDLIVVDSIQTIYHPEISSAPGSVSQVRESTQSLMHIAKQMNIATFIVGHVTKEGQIAGPRLLEHMVDTVLYFEGDEHHAYRILRAVKNRFGSTNEMGIFEMKQSGLKSVMNPSEMFLEERSTNVAGSTIVATMEGTRPLLIEVQALVTPTTFNNPRRMATGIDHNRLSLLMAVLEKKEGYLLQQQDAYIKVAGGVKLSEPAVDLSIIVATASSFKDQAVDGLDCFIGEVGLTGEVRRVSRIEQRVQEAAKLGFKRAIIPKNNIGGWHFPKGIEVIGVTSVNEALKYALK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	AP019561	Staphylococcus phage SP197 DNA, complete genome	14474-14502	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MF428481	Staphylococcus phage SN8, complete genome	5496-5524	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MT423824	Staphylococcus virus pSp_SNUABM-S, complete genome	29745-29773	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MT423823	Staphylococcus virus pSp_SNUABM-J, complete genome	30486-30514	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NC_007047	Staphylococcus phage 187, complete genome	4980-5008	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	AP019560	Staphylococcus phage SP120 DNA, complete genome	38445-38473	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MF428478	Staphylococcus phage SN13, complete genome	5496-5524	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MK075006	Staphylococcus phage phiSP119-3, complete genome	26774-26802	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MF428479	Staphylococcus phage SN11, complete genome	5496-5524	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	KX827370	Staphylococcus phage SpT252, complete genome	34400-34428	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	KX827368	Staphylococcus phage SpT5, complete genome	34111-34139	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	AY954950	Bacteriophage 187, complete genome	4980-5008	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	AP019562	Staphylococcus phage SP276 DNA, complete genome	35801-35829	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MF428480	Staphylococcus phage SN10, complete genome	5496-5524	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	KX827369	Staphylococcus phage SpT152, complete genome	23508-23536	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MK075003	Staphylococcus phage phiSP44-1, complete genome	23388-23416	0	1.0
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	MN028536	Staphylococcus phage vB_SpsM_WIS42, complete genome	5656-5684	0	1.0
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	AP019561	Staphylococcus phage SP197 DNA, complete genome	37112-37140	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	MF428481	Staphylococcus phage SN8, complete genome	28164-28192	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	AP019560	Staphylococcus phage SP120 DNA, complete genome	20735-20763	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	MF428478	Staphylococcus phage SN13, complete genome	28862-28890	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	MF428479	Staphylococcus phage SN11, complete genome	28140-28168	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	KX827370	Staphylococcus phage SpT252, complete genome	16951-16979	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	KX827368	Staphylococcus phage SpT5, complete genome	16976-17004	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	AP019562	Staphylococcus phage SP276 DNA, complete genome	17802-17830	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	MF428480	Staphylococcus phage SN10, complete genome	28140-28168	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	MK075003	Staphylococcus phage phiSP44-1, complete genome	7529-7557	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	MN028536	Staphylococcus phage vB_SpsM_WIS42, complete genome	28300-28328	3	0.897
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	KX827369	Staphylococcus phage SpT152, complete genome	5726-5754	3	0.897
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	AY940168	Prochlorococcus phage P-SSM4, complete genome	9840-9868	4	0.862
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	JF974306	Cyanophage P-SS1 strain P-SS1, * SEQUENCING IN PROGRESS *, 2 unordered pieces	73715-73743	4	0.862
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	HQ634176	Cyanophage P-RSM3 genomic sequence	76365-76393	4	0.862
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NZ_KJ776583	Clostridium botulinum strain KapchunkaB3 plasmid pKAPB3, complete sequence	30321-30349	5	0.828
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NZ_KJ776579	Clostridium botulinum strain KapchunkaB2 plasmid pKAPB2, complete sequence	30321-30349	5	0.828
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	NC_021559	Prochlorococcus phage P-SSM3 genomic sequence	89632-89660	5	0.828
NZ_CP020773_3	3.5\|1522966\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522966-1522994	29	NC_009933	Acaryochloris marina MBIC11017 plasmid pREB8, complete sequence	70823-70851	5	0.828
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NZ_KJ776585	Clostridium botulinum strain DB2 plasmid pDB2, complete sequence	30312-30340	6	0.793
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NC_014457	Clostridium phage phiCTP1, complete genome	25311-25340	6	0.8
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	MN694331	Marine virus AFVG_250M889, complete genome	3319-3347	6	0.793
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	AP014128	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C44-MedDCM-OCT-S32-C97, * SEQUENCING IN PROGRESS *	9023-9051	6	0.793
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	NZ_CP024792	Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence	4489-4517	6	0.793
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	NZ_CP045013	Enterococcus faecium strain LAC7.2 plasmid pI, complete sequence	165242-165270	6	0.793
NZ_CP020773_3	3.2\|1522768\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522768-1522796	29	MG945422	UNVERIFIED: Microviridae sp. isolate 4310-1711, complete genome	482-510	6	0.793
NZ_CP020773_3	3.5\|1522966\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522966-1522994	29	NC_009932	Acaryochloris marina MBIC11017 plasmid pREB7, complete sequence	45762-45790	6	0.793
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	66423-66451	7	0.759
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	68660-68688	7	0.759
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	79376-79404	7	0.759
NZ_CP020773_2	2.1\|588067\|29\|NZ_CP020773\|CRISPRCasFinder,CRT	588067-588095	29	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	111861-111889	7	0.759
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP021670	Bacillus licheniformis strain SRCM100141 plasmid pBL141-2 sequence	77503-77532	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP014843	Bacillus licheniformis strain SCDB 14 plasmid pSCDB14, complete sequence	195509-195538	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	MT438761	Listeria virus P61, complete genome	24193-24222	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	MT668624	Listeria phage LP-Mix_6.2, complete genome	13791-13820	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	MT178766	Listeria virus P100plus, complete genome	114478-114507	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	MT178767	Listeria virus P200, complete genome	114479-114508	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	DQ004855	Listeria bacteriophage P100, complete genome	110833-110862	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NC_041862	Listeria phage LP-064, complete genome	22405-22434	7	0.767
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	JX126918	Listeria phage LP-125, complete genome	22404-22433	7	0.767
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	NZ_CP045225	Clostridioides difficile strain TW11 plasmid p_TW11, complete sequence	901-929	7	0.759
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	723745-723773	7	0.759
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	MH542234	Staphylococcus phage Terranova, complete genome	2080-2108	7	0.759
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	MH321491	Staphylococcus phage Twillingate, complete genome	1945-1973	7	0.759
NZ_CP020773_3	3.2\|1522768\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522768-1522796	29	CP013001	Bacillus thuringiensis strain XL6 plasmid, complete sequence	360126-360154	7	0.759
NZ_CP020773_3	3.3\|1522834\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522834-1522862	29	NZ_CP034187	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed3, complete sequence	20520-20548	7	0.759
NZ_CP020773_3	3.7\|1523098\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1523098-1523126	29	MG459987	Klebsiella phage Sugarland, complete genome	7454-7482	7	0.759
NZ_CP020773_3	3.7\|1523098\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1523098-1523126	29	MK521907	Klebsiella phage vB_KpnS_FZ41, complete genome	103137-103165	7	0.759
NZ_CP020773_2	2.4\|588264\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588264-588293	30	NZ_CP007144	Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence	236723-236752	8	0.733
NZ_CP020773_2	2.4\|588264\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588264-588293	30	MN855976	Siphoviridae sp. isolate 68, complete genome	6437-6466	8	0.733
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	NC_023288	Exiguobacterium sp. S3-2 plasmid pMC2, complete sequence	5866-5894	8	0.724
NZ_CP020773_2	2.5\|588330\|29\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588330-588358	29	KT351738	Uncultured bacterium plasmid Drgb7, complete sequence	4989-5017	8	0.724
NZ_CP020773_3	3.1\|1522702\|29\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1522702-1522730	29	MN694394	Marine virus AFVG_250M672, complete genome	20734-20762	8	0.724
NZ_CP020773_3	3.8\|1523164\|30\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1523164-1523193	30	MN694739	Marine virus AFVG_250M678, complete genome	4596-4625	8	0.733
NZ_CP020773_3	3.8\|1523164\|30\|NZ_CP020773\|PILER-CR,CRISPRCasFinder,CRT	1523164-1523193	30	MH572437	Microviridae sp. isolate SD_MC_29, complete genome	2105-2134	8	0.733
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP013278	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-3-235K, complete sequence	230630-230659	9	0.7
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NC_018509	Bacillus thuringiensis HD-789 plasmid pBTHD789-2, complete sequence	224514-224543	9	0.7
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP051859	Bacillus thuringiensis serovar israelensis strain BGSC 4Q7rifR plasmid pBtic235, complete sequence	101733-101762	9	0.7
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP009347	Bacillus thuringiensis HD1002 plasmid 3, complete sequence	140489-140518	9	0.7
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP045025	Bacillus thuringiensis strain JW-1 plasmid p3, complete sequence	230630-230659	9	0.7
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP053971	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed3, complete sequence	80241-80270	9	0.7
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	NZ_CP039724	Bacillus thuringiensis strain BT-59 plasmid p3, complete sequence	138100-138129	9	0.7
NZ_CP020773_2	2.2\|588132\|30\|NZ_CP020773\|CRISPRCasFinder,CRT,PILER-CR	588132-588161	30	MN103542	Enterococcus phage vB_EfaS_EF1c55, complete genome	12735-12764	9	0.7

1. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to AP019561 (Staphylococcus phage SP197 DNA, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

2. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MF428481 (Staphylococcus phage SN8, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

3. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MT423824 (Staphylococcus virus pSp_SNUABM-S, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

4. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MT423823 (Staphylococcus virus pSp_SNUABM-J, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

5. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NC_007047 (Staphylococcus phage 187, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

6. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to AP019560 (Staphylococcus phage SP120 DNA, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

7. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MF428478 (Staphylococcus phage SN13, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

8. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

9. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MF428479 (Staphylococcus phage SN11, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

10. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to KX827370 (Staphylococcus phage SpT252, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

11. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to KX827368 (Staphylococcus phage SpT5, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

12. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to AY954950 (Bacteriophage 187, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

13. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to AP019562 (Staphylococcus phage SP276 DNA, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

14. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MF428480 (Staphylococcus phage SN10, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

15. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to KX827369 (Staphylococcus phage SpT152, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

16. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MK075003 (Staphylococcus phage phiSP44-1, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

17. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to MN028536 (Staphylococcus phage vB_SpsM_WIS42, complete genome) position: , mismatch: 0, identity: 1.0

aatgcttccacattgattaaattgttttc	CRISPR spacer
aatgcttccacattgattaaattgttttc	Protospacer
*****************************

18. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to AP019561 (Staphylococcus phage SP197 DNA, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcacctgcatcaagcttttgg	Protospacer
* ********************.*****.

19. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MF428481 (Staphylococcus phage SN8, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagtttttgg	Protospacer
* ********.*****************.

20. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to AP019560 (Staphylococcus phage SP120 DNA, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagtttttgg	Protospacer
* ********.*****************.

21. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MF428478 (Staphylococcus phage SN13, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcacctgcatcaagcttttgg	Protospacer
* ********************.*****.

22. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MF428479 (Staphylococcus phage SN11, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcacctgcatcaagcttttgg	Protospacer
* ********************.*****.

23. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to KX827370 (Staphylococcus phage SpT252, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagtttttgg	Protospacer
* ********.*****************.

24. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to KX827368 (Staphylococcus phage SpT5, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagtttttgg	Protospacer
* ********.*****************.

25. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to AP019562 (Staphylococcus phage SP276 DNA, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagtttttgg	Protospacer
* ********.*****************.

26. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MF428480 (Staphylococcus phage SN10, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagtttttgg	Protospacer
* ********.*****************.

27. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MK075003 (Staphylococcus phage phiSP44-1, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcacctgcatcaagcttttgg	Protospacer
* ********************.*****.

28. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MN028536 (Staphylococcus phage vB_SpsM_WIS42, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagtttttgg	Protospacer
* ********.*****************.

29. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to KX827369 (Staphylococcus phage SpT152, complete genome) position: , mismatch: 3, identity: 0.897

atccatattcacctgcatcaagtttttga	CRISPR spacer
aaccatattcgcctgcatcaagcttttga	Protospacer
* ********.***********.******

30. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to AY940168 (Prochlorococcus phage P-SSM4, complete genome) position: , mismatch: 4, identity: 0.862

---cagcttgtgcatcttcttttaattgttta	CRISPR spacer
acgcagc---tgcatcttcttttaatttttta	Protospacer
   ****   ***************** ****

31. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to JF974306 (Cyanophage P-SS1 strain P-SS1, *** SEQUENCING IN PROGRESS ***, 2 unordered pieces) position: , mismatch: 4, identity: 0.862

---cagcttgtgcatcttcttttaattgttta	CRISPR spacer
acgcagc---tgcatcttcttttaatttttta	Protospacer
   ****   ***************** ****

32. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to HQ634176 (Cyanophage P-RSM3 genomic sequence) position: , mismatch: 4, identity: 0.862

---cagcttgtgcatcttcttttaattgttta	CRISPR spacer
acgcagc---tgcatcttcttttaatttttta	Protospacer
   ****   ***************** ****

33. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NZ_KJ776583 (Clostridium botulinum strain KapchunkaB3 plasmid pKAPB3, complete sequence) position: , mismatch: 5, identity: 0.828

aatgcttccacattgattaaattgttttc	CRISPR spacer
tttgcttccacatttattaaattgtttaa	Protospacer
  ************ ************

34. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NZ_KJ776579 (Clostridium botulinum strain KapchunkaB2 plasmid pKAPB2, complete sequence) position: , mismatch: 5, identity: 0.828

aatgcttccacattgattaaattgttttc	CRISPR spacer
tttgcttccacatttattaaattgtttaa	Protospacer
  ************ ************

35. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NC_021559 (Prochlorococcus phage P-SSM3 genomic sequence) position: , mismatch: 5, identity: 0.828

---cagcttgtgcatcttcttttaattgttta	CRISPR spacer
atgcagc---agcatcttcttttaatttttta	Protospacer
   ****    **************** ****

36. spacer 3.5|1522966|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NC_009933 (Acaryochloris marina MBIC11017 plasmid pREB8, complete sequence) position: , mismatch: 5, identity: 0.828

ggagttagagaatactttcgacaactggc	CRISPR spacer
ggagttagagaatacgttcgacgtgttgc	Protospacer
*************** ******.  * **

37. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NZ_KJ776585 (Clostridium botulinum strain DB2 plasmid pDB2, complete sequence) position: , mismatch: 6, identity: 0.793

aatgcttccacattgattaaattgttttc	CRISPR spacer
tttgctcccacatttattaaattgtttaa	Protospacer
  ****.******* ************

38. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NC_014457 (Clostridium phage phiCTP1, complete genome) position: , mismatch: 6, identity: 0.8

taaagataaggaagcaattaaattatacat	CRISPR spacer
aaaagaaaaggaagcaattaaagtaaaaaa	Protospacer
 ***** *************** ** * *

39. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MN694331 (Marine virus AFVG_250M889, complete genome) position: , mismatch: 6, identity: 0.793

atccatattcacctgcatcaagtttttga	CRISPR spacer
gaccatattcacctgcatcacgtttgagt	Protospacer
. ****************** ****  *

40. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to AP014128 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C44-MedDCM-OCT-S32-C97, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.793

cagcttgtgcatcttcttttaattgttta	CRISPR spacer
attcttttgcatattcttttaattgtttt	Protospacer
   *** ***** ***************

41. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024792 (Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence) position: , mismatch: 6, identity: 0.793

cagcttgtgcatcttcttttaattgttta	CRISPR spacer
gagtttgtgaatcttcttttaattttaga	Protospacer
 **.***** ************** *  *

42. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045013 (Enterococcus faecium strain LAC7.2 plasmid pI, complete sequence) position: , mismatch: 6, identity: 0.793

--cagcttgtgcatcttcttttaattgttta	CRISPR spacer
ggcaatt--tgcatcttcttttcattgtttc	Protospacer
  **..*  ************* *******

43. spacer 3.2|1522768|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MG945422 (UNVERIFIED: Microviridae sp. isolate 4310-1711, complete genome) position: , mismatch: 6, identity: 0.793

ttcgttatcattcggaaagataaaaccga	CRISPR spacer
ttcaaaatctttcggaaagataaaaccat	Protospacer
***.  *** *****************.

44. spacer 3.5|1522966|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NC_009932 (Acaryochloris marina MBIC11017 plasmid pREB7, complete sequence) position: , mismatch: 6, identity: 0.793

ggagttagagaatactttcgacaactggc	CRISPR spacer
ggagttagagaatacgttcgatgtgttgc	Protospacer
*************** *****..  * **

45. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 7, identity: 0.759

aatgcttccacattgattaaattgttttc	CRISPR spacer
ataaattcctcatttattaaattgttttt	Protospacer
*  . **** **** *************.

46. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 7, identity: 0.759

aatgcttccacattgattaaattgttttc	CRISPR spacer
ataaattcctcatttattaaattgttttt	Protospacer
*  . **** **** *************.

47. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 7, identity: 0.759

aatgcttccacattgattaaattgttttc	CRISPR spacer
ataaattcctcatttattaaattgttttt	Protospacer
*  . **** **** *************.

48. spacer 2.1|588067|29|NZ_CP020773|CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 7, identity: 0.759

aatgcttccacattgattaaattgttttc	CRISPR spacer
ataaattcctcatttattaaattgttttt	Protospacer
*  . **** **** *************.

49. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021670 (Bacillus licheniformis strain SRCM100141 plasmid pBL141-2 sequence) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat	CRISPR spacer
agaagataatgaagcaattgaattattccc	Protospacer
 .******* *********.****** * .

50. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014843 (Bacillus licheniformis strain SCDB 14 plasmid pSCDB14, complete sequence) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat	CRISPR spacer
agaagataatgaagcaattgaattattccc	Protospacer
 .******* *********.****** * .

51. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MT438761 (Listeria virus P61, complete genome) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat---	CRISPR spacer
gaaagataaggaagctattaa---aaatatgac	Protospacer
 ************** *****   * *.**

52. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MT668624 (Listeria phage LP-Mix_6.2, complete genome) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat---	CRISPR spacer
gaaagataaggaagctattaa---aaatatgac	Protospacer
 ************** *****   * *.**

53. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MT178766 (Listeria virus P100plus, complete genome) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat---	CRISPR spacer
gaaagataaggaagctattaa---aaatatgac	Protospacer
 ************** *****   * *.**

54. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MT178767 (Listeria virus P200, complete genome) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat---	CRISPR spacer
gaaagataaggaagctattaa---aaatatgac	Protospacer
 ************** *****   * *.**

55. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to DQ004855 (Listeria bacteriophage P100, complete genome) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat---	CRISPR spacer
gaaagataaggaagctattaa---aaatatgac	Protospacer
 ************** *****   * *.**

56. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NC_041862 (Listeria phage LP-064, complete genome) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat---	CRISPR spacer
gaaagataaggaagctattaa---aaatatgac	Protospacer
 ************** *****   * *.**

57. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to JX126918 (Listeria phage LP-125, complete genome) position: , mismatch: 7, identity: 0.767

taaagataaggaagcaattaaattatacat---	CRISPR spacer
gaaagataaggaagctattaa---aaatatgac	Protospacer
 ************** *****   * *.**

58. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045225 (Clostridioides difficile strain TW11 plasmid p_TW11, complete sequence) position: , mismatch: 7, identity: 0.759

cagcttgtgcatcttcttttaattgttta	CRISPR spacer
atagaagtgcttcttcttttaattgttta	Protospacer
  .   **** ******************

59. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 7, identity: 0.759

cagcttgtgcatcttcttttaattgttta	CRISPR spacer
tgattggtggattttcttttaattgttta	Protospacer
....* *** **.****************

60. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MH542234 (Staphylococcus phage Terranova, complete genome) position: , mismatch: 7, identity: 0.759

cagcttgtgcatcttcttttaattgttta	CRISPR spacer
tatattgtgaatcttcttttaattcttgc	Protospacer
.*  ***** ************** **

61. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MH321491 (Staphylococcus phage Twillingate, complete genome) position: , mismatch: 7, identity: 0.759

cagcttgtgcatcttcttttaattgttta	CRISPR spacer
tatattgtgaatcttcttttaattcttgc	Protospacer
.*  ***** ************** **

62. spacer 3.2|1522768|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to CP013001 (Bacillus thuringiensis strain XL6 plasmid, complete sequence) position: , mismatch: 7, identity: 0.759

ttcgttatcattcggaaagataaaaccga	CRISPR spacer
agttttataattcggaaaaataaaaccta	Protospacer
  . **** *********.******** *

63. spacer 3.3|1522834|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034187 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

aaaaagttttatcaatccgcagcttagtt	CRISPR spacer
aaaaagttttatcaatcggcaatcagctt	Protospacer
***************** ***... . **

64. spacer 3.7|1523098|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MG459987 (Klebsiella phage Sugarland, complete genome) position: , mismatch: 7, identity: 0.759

tagtgatgttggcgagcctaaattaattt	CRISPR spacer
caaaaacgttagcgagcctaaattaatta	Protospacer
.*. .*.***.*****************

65. spacer 3.7|1523098|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MK521907 (Klebsiella phage vB_KpnS_FZ41, complete genome) position: , mismatch: 7, identity: 0.759

tagtgatgttggcgagcctaaattaattt	CRISPR spacer
caaaaacgttagcgagcctaaattaatta	Protospacer
.*. .*.***.*****************

66. spacer 2.4|588264|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007144 (Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence) position: , mismatch: 8, identity: 0.733

gaacattatctgtgggatatttacgaacca	CRISPR spacer
gttcattaactgtgggatatttactcattc	Protospacer
*  ***** ***************  *..

67. spacer 2.4|588264|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MN855976 (Siphoviridae sp. isolate 68, complete genome) position: , mismatch: 8, identity: 0.733

gaacattatctgtgggatatttacgaacca	CRISPR spacer
cgacattatctgtggtatatttattatctt	Protospacer
 .************* *******. * *.

68. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NC_023288 (Exiguobacterium sp. S3-2 plasmid pMC2, complete sequence) position: , mismatch: 8, identity: 0.724

atccatattcacctgcatcaagtttttga	CRISPR spacer
cgccataatcacccgcatcaagtttcgcg	Protospacer
  ***** *****.***********.  .

69. spacer 2.5|588330|29|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to KT351738 (Uncultured bacterium plasmid Drgb7, complete sequence) position: , mismatch: 8, identity: 0.724

atccatattcacctgcatcaagtttttga	CRISPR spacer
tcatttattcacctgtatcaagttttgaa	Protospacer
 . . **********.********** .*

70. spacer 3.1|1522702|29|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MN694394 (Marine virus AFVG_250M672, complete genome) position: , mismatch: 8, identity: 0.724

cagcttgtgcatcttcttttaattgttta	CRISPR spacer
gagcttgtgcttcttcttttgattcaaat	Protospacer
 ********* *********.***

71. spacer 3.8|1523164|30|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MN694739 (Marine virus AFVG_250M678, complete genome) position: , mismatch: 8, identity: 0.733

ataatcaaaactcgataaaaaaactttaaa	CRISPR spacer
ataaacaaaactccataaaaaaagccgcca	Protospacer
**** ******** ********* ..   *

72. spacer 3.8|1523164|30|NZ_CP020773|PILER-CR,CRISPRCasFinder,CRT matches to MH572437 (Microviridae sp. isolate SD_MC_29, complete genome) position: , mismatch: 8, identity: 0.733

ataatcaaaactcgataaaaaaactttaaa	CRISPR spacer
gaaacctaaactcgataaaaaaactggcga	Protospacer
. **.* ******************   .*

73. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013278 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-3-235K, complete sequence) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
ggtagataaagaagcaattcaattattaga	Protospacer
 . ******.********* ******  .

74. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NC_018509 (Bacillus thuringiensis HD-789 plasmid pBTHD789-2, complete sequence) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
ggtagataaagaagcaattcaattattaga	Protospacer
 . ******.********* ******  .

75. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051859 (Bacillus thuringiensis serovar israelensis strain BGSC 4Q7rifR plasmid pBtic235, complete sequence) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
ggtagataaagaagcaattcaattattaga	Protospacer
 . ******.********* ******  .

76. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009347 (Bacillus thuringiensis HD1002 plasmid 3, complete sequence) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
ggtagataaagaagcaattcaattattaga	Protospacer
 . ******.********* ******  .

77. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045025 (Bacillus thuringiensis strain JW-1 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
ggtagataaagaagcaattcaattattaga	Protospacer
 . ******.********* ******  .

78. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053971 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
ggtagataaagaagcaattcaattattaga	Protospacer
 . ******.********* ******  .

79. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039724 (Bacillus thuringiensis strain BT-59 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
ggtagataaagaagcaattcaattattaga	Protospacer
 . ******.********* ******  .

80. spacer 2.2|588132|30|NZ_CP020773|CRISPRCasFinder,CRT,PILER-CR matches to MN103542 (Enterococcus phage vB_EfaS_EF1c55, complete genome) position: , mismatch: 9, identity: 0.7

taaagataaggaagcaattaaattatacat	CRISPR spacer
aaaagctaaggaagcaattaaaaaggttaa	Protospacer
 **** ****************  .  .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

97214 : 106044

uncultured_Mediterranean_phage(50.0%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085236080.1\|97214_97733_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.0e-26	48.8
WP_145951841.1\|97744_100030_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.1e-71	30.6
WP_085236084.1\|100144_102424_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	5.0e-29	32.8
WP_085236086.1\|102565_102829_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	9.8e-06	45.6
WP_085236088.1\|102845_103985_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	8.1e-89	46.9
WP_085236090.1\|104002_105028_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_085236092.1\|105045_106044_-	Holliday junction branch migration DNA helicase RuvB	E3T4M7	Cafeteria_roenbergensis_virus	1.8e-07	27.9

DBSCAN-SWA_2

222394 : 231707

Staphylococcus_phage(85.71%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085236271.1\|222394_223669_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	1.9e-33	71.3
WP_085236273.1\|223905_225192_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.2e-26	28.5
WP_085236276.1\|225803_226115_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.7e-33	67.0
WP_085236278.1\|226142_228554_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	80.2
WP_085236280.1\|228864_230046_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	4.0e-139	63.3
WP_085236282.1\|230193_231147_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.8e-58	74.8
WP_085236284.1\|231143_231707_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	2.4e-57	57.3

DBSCAN-SWA_3

235824 : 257501

Staphylococcus_phage(95.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085236294.1\|235824_236808_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	8.5e-119	66.0
WP_085236296.1\|237087_237552_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.8e-47	64.0
WP_085236298.1\|237569_238751_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.7e-145	63.4
WP_085236300.1\|238764_239394_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	7.0e-58	55.2
WP_085236303.1\|239398_240442_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.2e-109	55.5
WP_085236305.1\|240899_242471_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	3.8e-12	58.1
WP_085236307.1\|243103_243967_-	glucosaminidase domain-containing protein	A0A0E3T9J6	Staphylococcus_phage	1.1e-37	39.5
WP_085236309.1\|244121_244343_-	hypothetical protein	NA	NA	NA	NA
WP_085236311.1\|244539_245034_+	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	3.5e-20	39.4
WP_085238391.1\|245033_245471_+	hypothetical protein	NA	NA	NA	NA
WP_085236313.1\|245467_245917_-	magnesium transporter	A0A2H4PQT8	Staphylococcus_phage	1.2e-08	35.3
WP_085236315.1\|246082_246793_-	transaldolase	E3SKN5	Synechococcus_phage	2.9e-20	38.3
WP_085236317.1\|246945_247248_+	hypothetical protein	NA	NA	NA	NA
WP_085236319.1\|247278_247644_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	4.5e-25	51.7
WP_085236322.1\|247640_247988_+	CrcB family protein	NA	NA	NA	NA
WP_085236324.1\|248129_248966_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.8e-114	71.4
WP_085236327.1\|249199_250111_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	2.5e-85	66.7
WP_085236330.1\|250199_251399_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-182	81.6
WP_085236333.1\|251867_253454_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	1.3e-238	75.2
WP_103322017.1\|253610_254360_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.5e-78	60.9
WP_085238392.1\|254364_254835_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.1e-39	51.9
WP_085236338.1\|254887_255163_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	4.7e-27	71.2
WP_085236341.1\|255108_256101_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	3.4e-75	46.1
WP_085236343.1\|256103_257501_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.1e-135	52.7

DBSCAN-SWA_4

267316 : 319958

Staphylococcus_phage(40.0%)

transposase,tRNA,integrase

attL 265726:265742|attR 284077:284093

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
265726:265742	attL	NA	NA	NA	NA
WP_085236365.1\|267316_267589_+	hypothetical protein	U3PJ31	Staphylococcus_phage	8.0e-11	37.1
WP_085236367.1\|267637_268246_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.5e-49	49.2
WP_145951843.1\|268278_269407_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-80	54.7
WP_085236368.1\|269379_269625_-	hypothetical protein	NA	NA	NA	NA
WP_085236371.1\|269621_270905_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.6e-13	29.7
WP_103322076.1\|270982_271399_+\|integrase	tyrosine-type recombinase/integrase	U3PJ31	Staphylococcus_phage	4.6e-26	45.0
WP_085236373.1\|272162_272738_+	recombinase family protein	E5FFF9	Burkholderia_phage	6.9e-20	36.8
WP_085236376.1\|275887_276235_-	complement inhibitor SCIN family protein	A7TWS0	Staphylococcus_phage	3.6e-16	44.8
WP_085236378.1\|277101_277656_-	serine hydrolase family protein	NA	NA	NA	NA
WP_085236380.1\|278015_279419_-	protoporphyrinogen oxidase	NA	NA	NA	NA
WP_085236382.1\|279424_280357_-	ferrochelatase	NA	NA	NA	NA
WP_085236384.1\|280394_281429_-	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_085236387.1\|281757_282267_+	signal transduction protein TRAP	NA	NA	NA	NA
WP_085236389.1\|282330_283545_-	ABC transporter permease	NA	NA	NA	NA
WP_085236391.1\|283541_284279_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-25	28.7
284077:284093	attR	NA	NA	NA	NA
WP_085236393.1\|284414_284840_+	HIT family protein	NA	NA	NA	NA
WP_085236395.1\|284916_285273_+	hypothetical protein	NA	NA	NA	NA
WP_085236397.1\|285372_285903_+	HTH-type transcriptional regulator Hpr	NA	NA	NA	NA
WP_085236399.1\|285950_286502_+	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_085236401.1\|286753_287722_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_085236403.1\|287946_288888_-	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
WP_085236405.1\|288907_291832_-	AAA family ATPase	NA	NA	NA	NA
WP_085236407.1\|291835_293023_-	DNA repair exonuclease	NA	NA	NA	NA
WP_085236409.1\|293209_293554_-	YlbF/YmcA family competence regulator	NA	NA	NA	NA
WP_085236412.1\|293638_294769_-	DUF445 domain-containing protein	NA	NA	NA	NA
WP_085236415.1\|294947_295412_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085236417.1\|296354_297644_+	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_085236419.1\|298033_298906_+	cation transporter	NA	NA	NA	NA
WP_085236421.1\|298998_299625_-	response regulator transcription factor	NA	NA	NA	NA
WP_085236423.1\|299599_300748_-	GAF domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_085236425.1\|300890_301721_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_085238393.1\|301983_304125_-	RNA degradosome polyphosphate kinase	NA	NA	NA	NA
WP_085236427.1\|304222_305749_-	exopolyphosphatase	NA	NA	NA	NA
WP_085236429.1\|305770_307156_-	class II fumarate hydratase	NA	NA	NA	NA
WP_085236430.1\|307465_307900_-	hypothetical protein	NA	NA	NA	NA
WP_169710755.1\|308346_308442_+	hypothetical protein	NA	NA	NA	NA
WP_169710756.1\|308677_308842_-	hypothetical protein	NA	NA	NA	NA
WP_085236431.1\|308860_309463_-	glucosamine-6-phosphate isomerase	NA	NA	NA	NA
WP_085236432.1\|309631_310102_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_085236433.1\|310101_311232_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_085236434.1\|311407_312139_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-32	39.1
WP_085236435.1\|312131_313592_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_085236436.1\|313797_314856_-	PTS transporter subunit IIC	NA	NA	NA	NA
WP_085236437.1\|315088_316468_-	MAP domain-containing protein	NA	NA	NA	NA
WP_085236441.1\|318270_318558_+\|transposase	transposase	NA	NA	NA	NA
WP_142382186.1\|318605_318857_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_103322067.1\|318828_319958_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-80	54.7

DBSCAN-SWA_5

423326 : 485087

uncultured_virus(14.29%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085236647.1\|423326_423884_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_103322067.1\|425163_426292_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-80	54.7
WP_085236649.1\|428101_428527_+	hypothetical protein	NA	NA	NA	NA
WP_085236651.1\|429439_431059_-	chaperonin GroEL	A0A240F779	uncultured_virus	1.2e-157	54.2
WP_085236653.1\|431105_431393_-	co-chaperone GroES	A0A221S4A8	uncultured_virus	1.6e-14	40.2
WP_085236656.1\|431561_432329_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_169710761.1\|432733_433921_-	hypothetical protein	NA	NA	NA	NA
WP_085236660.1\|434189_435005_+	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_145951851.1\|435381_435462_-	delta-lysin family phenol-soluble modulin	NA	NA	NA	NA
WP_085236662.1\|435853_436420_+	accessory gene regulator AgrB	NA	NA	NA	NA
WP_085236664.1\|436421_436556_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_085236666.1\|436584_437910_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_085236668.1\|437890_438607_+	response regulator transcription factor	A0A2H4J4Z6	uncultured_Caudovirales_phage	4.2e-27	33.5
WP_085236670.1\|438774_440262_-	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	1.7e-09	23.8
WP_085236672.1\|440841_441489_-	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_085236674.1\|441641_443600_+	ABC-F type ribosomal protection protein	A0A2K9L3Z8	Tupanvirus	9.4e-53	27.5
WP_085236676.1\|444106_445129_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	7.8e-59	38.2
WP_085236678.1\|445121_445592_-	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_085236680.1\|445570_446227_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_085236683.1\|446207_446666_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_085236685.1\|447188_448877_+	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_085236688.1\|448895_450650_+	biosynthetic-type acetolactate synthase large subunit	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	5.0e-53	28.4
WP_085236690.1\|450646_451120_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_085236692.1\|451153_452158_+	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_085236694.1\|452178_453717_+	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	5.7e-13	26.6
WP_085236696.1\|453706_454756_+	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_085236698.1\|454759_456130_+	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_085236700.1\|456132_456705_+	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_085236702.1\|456717_457986_+	threonine ammonia-lyase IlvA	NA	NA	NA	NA
WP_085236704.1\|464191_464650_-	SprT family protein	NA	NA	NA	NA
WP_085238399.1\|464642_466793_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_085238400.1\|467128_468448_+\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	9.6e-09	22.6
WP_085236706.1\|468498_469269_-	RNA polymerase sigma factor SigB	A0A0A0RNH9	Bacillus_phage	9.8e-22	34.3
WP_085238401.1\|469243_469723_-	anti-sigma B factor RsbW	NA	NA	NA	NA
WP_085236708.1\|469727_470054_-	anti-sigma factor antagonist	NA	NA	NA	NA
WP_085236711.1\|470132_471137_-	PP2C family protein-serine/threonine phosphatase	NA	NA	NA	NA
WP_019169266.1\|471193_471547_-	type II toxin-antitoxin system PemK/MazF family toxin	Q332J9	Clostridium_botulinum_C_phage	2.4e-07	32.8
WP_085236713.1\|471547_471718_-	antitoxin MazE	NA	NA	NA	NA
WP_085236715.1\|471802_472951_-	alanine racemase	NA	NA	NA	NA
WP_085236717.1\|472984_473335_-	holo-ACP synthase	NA	NA	NA	NA
WP_103322025.1\|473331_473841_-	PH domain-containing protein	NA	NA	NA	NA
WP_085236722.1\|473846_475349_-	PH domain-containing protein	NA	NA	NA	NA
WP_085236725.1\|475341_475815_-	PH domain-containing protein	NA	NA	NA	NA
WP_085238400.1\|476157_477477_+\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	9.6e-09	22.6
WP_085236728.1\|477547_479035_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	3.7e-57	34.8
WP_085236731.1\|479448_480816_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_085236733.1\|480827_481898_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_085236735.1\|482051_483257_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_085236737.1\|483309_484041_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_085236739.1\|484061_485087_-\|protease	trypsin-like serine protease	NA	NA	NA	NA

DBSCAN-SWA_6

601931 : 629192

Lactococcus_phage(23.08%)

transposase,integrase

attL 612765:612824|attR 634784:634843

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_169710765.1\|601931_603060_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.6e-76	52.9
WP_085236836.1\|603710_604946_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.2e-101	47.4
WP_085236837.1\|604956_605724_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	3.5e-51	43.3
WP_169710750.1\|605703_605940_-	hypothetical protein	NA	NA	NA	NA
WP_085236839.1\|606026_606266_-	hypothetical protein	NA	NA	NA	NA
WP_085236840.1\|606262_606589_-	hypothetical protein	NA	NA	NA	NA
WP_085236841.1\|606666_607707_-	hypothetical protein	NA	NA	NA	NA
WP_085236842.1\|607696_608608_-	hypothetical protein	NA	NA	NA	NA
WP_085236843.1\|608769_609360_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.0e-50	52.9
WP_085236846.1\|611310_611697_-	hypothetical protein	NA	NA	NA	NA
WP_169710768.1\|611929_612376_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0P0I4A4	Acinetobacter_phage	3.4e-27	50.4
612765:612824	attL	NA	NA	NA	NA
WP_085236849.1\|613045_616678_-	hypothetical protein	NA	NA	NA	NA
WP_085236850.1\|616701_619668_-	type III restriction-modification system endonuclease	Q71TG1	Escherichia_phage	4.8e-125	31.6
WP_085236851.1\|619670_621548_-	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	1.1e-82	34.6
WP_085236852.1\|621548_621764_-	helix-turn-helix transcriptional regulator	A0A2K5B263	Erysipelothrix_phage	3.1e-10	41.4
WP_169710769.1\|622155_622326_-	hypothetical protein	NA	NA	NA	NA
WP_169710770.1\|623363_624179_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.4e-58	45.2
WP_103322067.1\|624284_625413_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-80	54.7
WP_085236845.1\|625443_625731_-\|transposase	transposase	NA	NA	NA	NA
WP_085236854.1\|626537_626720_+\|integrase	tyrosine-type recombinase/integrase	M1PFE2	Streptococcus_phage	5.2e-14	62.5
WP_085238406.1\|627459_628218_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.1e-53	43.5
WP_085236855.1\|628217_629192_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	7.6e-11	37.2
634784:634843	attR	NA	NA	NA	NA

DBSCAN-SWA_7

704280 : 711240

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085236933.1\|704280_705243_+	hydroxyacid dehydrogenase	M1HTA3	Paramecium_bursaria_Chlorella_virus	8.2e-26	28.9
WP_085236934.1\|705472_706123_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	8.6e-35	41.6
WP_085236935.1\|706196_706583_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	9.3e-05	36.5
WP_085236936.1\|706638_706920_-	ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	6.5e-08	35.3
WP_085236937.1\|706938_707739_-	ABC transporter permease	NA	NA	NA	NA
WP_162682398.1\|707753_708635_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.3e-17	29.1
WP_085236939.1\|709307_710435_-	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_085236940.1\|710463_711240_-	glucosaminidase domain-containing protein	Q4ZC50	Staphylococcus_virus	1.9e-36	40.2

DBSCAN-SWA_8

1262274 : 1271309

Lactococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085237339.1\|1262274_1264296_+	K(+)-transporting ATPase subunit B	E4ZFI9	Streptococcus_phage	4.4e-45	30.6
WP_085237340.1\|1264309_1264867_+	K(+)-transporting ATPase subunit C	NA	NA	NA	NA
WP_169710785.1\|1265417_1265765_-	hypothetical protein	NA	NA	NA	NA
WP_169710786.1\|1265889_1266054_+	hypothetical protein	NA	NA	NA	NA
WP_085237342.1\|1266080_1266899_-	hypothetical protein	A0A097PAT7	Streptococcus_pyogenes_phage	1.5e-52	46.1
WP_085237343.1\|1267252_1268488_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	8.7e-105	49.1
WP_085237344.1\|1268499_1269273_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.9e-51	43.8
WP_085237345.1\|1269339_1269693_-	SdpI family protein	NA	NA	NA	NA
WP_085237346.1\|1270043_1270352_-\|transposase	transposase	A0ZS58	Staphylococcus_virus	8.2e-28	61.9
WP_169710787.1\|1270595_1271309_-	AAA family ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	3.6e-10	27.9

DBSCAN-SWA_9

1335178 : 1381096

Staphylococcus_phage(31.58%)

transposase,tRNA,bacteriocin,protease,integrase

attL 1335300:1335315|attR 1377541:1377556

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142382191.1\|1335178_1335649_+\|integrase	phage integrase SAM-like domain-containing protein	NA	NA	NA	NA
1335300:1335315	attL	NA	NA	NA	NA
WP_169710790.1\|1335689_1336250_+\|integrase	phage integrase family protein	S4TP66	Salmonella_phage	6.9e-09	36.0
WP_085237400.1\|1336348_1336681_+	hypothetical protein	NA	NA	NA	NA
WP_085237401.1\|1336881_1337064_+	hypothetical protein	NA	NA	NA	NA
WP_085237402.1\|1337060_1337294_+	hypothetical protein	NA	NA	NA	NA
WP_085237403.1\|1338706_1338967_+	hypothetical protein	NA	NA	NA	NA
WP_014614928.1\|1339109_1339532_-	hypothetical protein	A0A1Q1PVU5	Staphylococcus_phage	4.1e-14	34.9
WP_085237404.1\|1339533_1340043_-	hypothetical protein	A0A1Q1PVV5	Staphylococcus_phage	9.0e-40	52.9
WP_085237405.1\|1340750_1342085_+	hypothetical protein	NA	NA	NA	NA
WP_085237406.1\|1342246_1343071_+	HNH endonuclease	A0A249XZV1	Enterococcus_phage	8.1e-06	41.2
WP_103322087.1\|1343987_1344062_+	DUF933 domain-containing protein	NA	NA	NA	NA
WP_085237407.1\|1344317_1345982_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	5.9e-64	30.7
WP_085237408.1\|1346212_1347649_-	B domain-containing protein	NA	NA	NA	NA
WP_085237409.1\|1347975_1348272_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_085237410.1\|1348293_1348797_+	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	2.5e-58	70.7
WP_014614919.1\|1348848_1349091_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_085237411.1\|1349644_1350220_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_085237413.1\|1350653_1351544_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-35	44.5
WP_085237414.1\|1351544_1352297_+	amino acid transporter	NA	NA	NA	NA
WP_085237415.1\|1352467_1354459_-	catalase	A0A2K9L572	Tupanvirus	1.8e-144	47.7
WP_085237416.1\|1354795_1355176_-	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_085237417.1\|1355394_1356384_+	biotin synthase BioB	NA	NA	NA	NA
WP_085237418.1\|1356528_1357479_+	DUF1002 domain-containing protein	NA	NA	NA	NA
WP_085237419.1\|1357760_1359284_-	alkyl hydroperoxide reductase subunit F	V9VEY6	Lactococcus_phage	9.7e-21	31.2
WP_085237420.1\|1359298_1359868_-	peroxiredoxin	NA	NA	NA	NA
WP_085237421.1\|1360429_1361185_+	oxygen-insensitive NADPH nitroreductase	NA	NA	NA	NA
WP_085237422.1\|1361397_1361688_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_085237423.1\|1361712_1363680_+	DUF1430 domain-containing protein	NA	NA	NA	NA
WP_085237424.1\|1363680_1364013_+	YxeA family protein	NA	NA	NA	NA
WP_085237425.1\|1364009_1364645_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.8e-21	33.7
WP_085237426.1\|1364745_1366137_-	L-cystine transporter	NA	NA	NA	NA
WP_085237427.1\|1366209_1367316_-	glycine oxidase ThiO	NA	NA	NA	NA
WP_085237428.1\|1367684_1368284_-	DNA-binding protein	NA	NA	NA	NA
WP_085237429.1\|1368396_1369071_-	hypothetical protein	NA	NA	NA	NA
WP_085237430.1\|1369316_1369739_-	general stress protein	NA	NA	NA	NA
WP_085237431.1\|1370200_1370785_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_085237432.1\|1370781_1372050_+	purine permease	Q9KX94	Enterobacteria_phage	3.6e-29	28.4
WP_085238434.1\|1372083_1373550_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	3.2e-98	41.2
WP_085237433.1\|1373573_1375115_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	6.8e-22	32.1
WP_085237434.1\|1375208_1376345_-\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	2.6e-71	39.5
WP_085237435.1\|1376437_1377067_-	helix-turn-helix transcriptional regulator	A0A1W6JQE6	Staphylococcus_phage	4.0e-45	47.1
WP_085237436.1\|1377220_1377448_+	helix-turn-helix transcriptional regulator	A0A1W6JQE8	Staphylococcus_phage	5.1e-11	56.6
WP_085237437.1\|1377425_1377686_+	hypothetical protein	NA	NA	NA	NA
1377541:1377556	attR	NA	NA	NA	NA
WP_103322067.1\|1377849_1378979_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-80	54.7
WP_085237438.1\|1379082_1380318_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	8.2e-103	47.7
WP_085236837.1\|1380328_1381096_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	3.5e-51	43.3

DBSCAN-SWA_10

1737259 : 1747331

Acinetobacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085237728.1\|1737259_1738309_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	3.1e-18	25.9
WP_085237729.1\|1738397_1738940_+	5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
WP_085237730.1\|1739207_1740710_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	6.1e-68	35.6
WP_085237731.1\|1741064_1742570_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.6e-71	36.8
WP_085237732.1\|1742840_1743341_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.4e-53	66.4
WP_085237733.1\|1743358_1744243_-	DMT family transporter	NA	NA	NA	NA
WP_085237734.1\|1744864_1745263_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	4.4e-42	62.1
WP_085237735.1\|1745225_1747331_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	85.6

DBSCAN-SWA_11

1781008 : 1786883

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085237766.1\|1781008_1781947_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	9.3e-83	49.2
WP_085237767.1\|1782242_1783151_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	9.5e-08	33.6
WP_085237768.1\|1783152_1784148_+	YvcK family protein	A1IMD5	Streptococcus_phage	5.3e-52	43.8
WP_085237769.1\|1784194_1785139_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.6e-53	39.9
WP_085237770.1\|1785706_1786294_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	8.2e-53	55.5
WP_085237771.1\|1786382_1786883_+	N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	6.8e-16	31.6

DBSCAN-SWA_12

1798936 : 1814511

Staphylococcus_phage(38.46%)

tail,capsid,portal,protease,terminase,integrase,head

attL 1798365:1798379|attR 1816310:1816324

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1798365:1798379	attL	NA	NA	NA	NA
WP_085237781.1\|1798936_1801297_+	ribonuclease R	Q0GXV6	Lactococcus_phage	5.6e-92	39.0
WP_085237782.1\|1801311_1801776_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.1e-68	83.8
WP_085237783.1\|1802312_1803419_-\|integrase	site-specific integrase	A0A1B2AQ00	Phage_Wrath	5.1e-80	43.1
WP_085237784.1\|1803421_1803997_-	helix-turn-helix domain-containing protein	A0A1W6JPB6	Staphylococcus_phage	3.5e-08	29.2
WP_085237785.1\|1804131_1804347_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085237786.1\|1804349_1804568_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085237787.1\|1804580_1804784_+	pathogenicity island protein	A0A1W6JQF4	Staphylococcus_phage	8.0e-24	76.1
WP_085237788.1\|1804785_1804995_+	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	8.8e-18	60.3
WP_085237789.1\|1804996_1805269_+	hypothetical protein	NA	NA	NA	NA
WP_085237790.1\|1805268_1805571_+	DUF1474 family protein	A0A2H4JB50	uncultured_Caudovirales_phage	1.4e-24	60.0
WP_085237791.1\|1805668_1808041_+	DNA primase	A0A2H4JCU9	uncultured_Caudovirales_phage	2.9e-149	42.8
WP_085237792.1\|1808356_1808698_+	pathogenicity island protein	A0A1W6JQD5	Staphylococcus_phage	2.1e-45	74.8
WP_085237793.1\|1808832_1810011_+\|portal	phage portal protein	A0A1L2BY94	Clostridium_phage	8.7e-62	36.8
WP_085237794.1\|1809997_1810564_+\|head,protease	HK97 family phage prohead protease	A0A1B1PA08	Enterococcus_phage	5.5e-22	35.9
WP_085237795.1\|1810565_1811795_+\|capsid	phage major capsid protein	NA	NA	NA	NA
WP_085237796.1\|1811853_1812135_+\|head,tail	phage gp6-like head-tail connector protein	A0A0S2GLH6	Bacillus_phage	1.8e-05	29.5
WP_085237798.1\|1812554_1812875_+	hypothetical protein	NA	NA	NA	NA
WP_085237799.1\|1812867_1814511_+\|terminase	terminase large subunit	A0A290GJW3	Caldibacillus_phage	2.7e-154	51.0
1816310:1816324	attR	NA	NA	NA	NA

DBSCAN-SWA_13

2022810 : 2031230

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085237968.1\|2022810_2023293_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.9e-21	44.9
WP_085237969.1\|2023279_2024413_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_085237970.1\|2024409_2025111_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-46	42.1
WP_085237971.1\|2025113_2025374_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_085237972.1\|2025375_2026047_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_085237973.1\|2026039_2028229_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.1e-140	38.8
WP_085238462.1\|2028207_2029629_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-49	33.0
WP_085237974.1\|2029632_2030664_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	5.3e-63	42.4
WP_085237975.1\|2030663_2031230_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.4e-27	38.9

DBSCAN-SWA_14

2115622 : 2121688

Staphylococcus_phage(100.0%)

holin,integrase

attL 2115541:2115561|attR 2126255:2126275

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2115541:2115561	attL	NA	NA	NA	NA
WP_085238048.1\|2115622_2116648_-\|integrase	site-specific integrase	A0A0D4DCG3	Staphylococcus_phage	3.9e-183	92.1
WP_085238049.1\|2116826_2117810_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	1.3e-164	90.8
WP_085238465.1\|2117857_2118121_-	hypothetical protein	A0A1W6JQ94	Staphylococcus_phage	8.8e-23	63.2
WP_085238050.1\|2118414_2119041_-	helix-turn-helix domain-containing protein	A0A1J0MG99	Staphylococcus_phage	3.2e-111	99.0
WP_169710803.1\|2119620_2120646_+	hypothetical protein	A0A1J0MFB0	Staphylococcus_phage	1.3e-173	87.1
WP_085238466.1\|2120665_2120920_+\|holin	phage holin	A0A1J0MFP5	Staphylococcus_phage	4.3e-35	86.9
WP_085238051.1\|2120932_2121688_+	CHAP domain-containing protein	A0A1J0MF88	Staphylococcus_phage	4.8e-146	96.0
2126255:2126275	attR	NA	NA	NA	NA

DBSCAN-SWA_15

2472476 : 2481029

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085238338.1\|2472476_2473853_-	ATP-dependent DNA helicase RecQ	A0A2K9L3P7	Tupanvirus	2.1e-54	31.0
WP_085238339.1\|2473845_2474793_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014613875.1\|2474897_2475146_+	ferredoxin	A0A127AYY7	Bacillus_phage	2.3e-17	53.3
WP_085238340.1\|2475507_2476053_-	ECF transporter S component	NA	NA	NA	NA
WP_085238341.1\|2476467_2478207_-	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	4.2e-20	28.7
WP_085238478.1\|2478193_2478916_-	response regulator transcription factor	W8CYM9	Bacillus_phage	5.9e-45	40.9
WP_085238342.1\|2479030_2479768_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_085238343.1\|2479768_2480311_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.8e-07	28.0
WP_085238344.1\|2480300_2481029_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.8e-10	34.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020773

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection