CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018418	Burkholderia pseudomallei strain 2002734728 chromosome 1, complete sequence	0 crisprs	RT,DinG,csa3,DEDDh,cas3,WYL	0	0	11	0
NZ_CP018419	Burkholderia pseudomallei strain 2002734728 chromosome 2, complete sequence	2 crisprs	cas3,csa3,DinG	10	16	1	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

40198 : 98134

Pseudomonas_phage(28.57%)

transposase,protease,plate,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085560609.1\|40198_41497_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_004527811.1\|41563_42646_+	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	6.7e-08	46.6
WP_004534980.1\|42689_43547_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_004186955.1\|43626_43935_+	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_004521981.1\|43949_44546_+	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_004521980.1\|44829_45618_+	dioxygenase	NA	NA	NA	NA
WP_004527813.1\|46093_47695_-	APC family permease	NA	NA	NA	NA
WP_004196837.1\|48128_48332_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.3e-21	73.1
WP_004191998.1\|48438_49902_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004555450.1\|50113_51376_-	Hsp70 family protein	NA	NA	NA	NA
WP_004198059.1\|52143_52749_-	nitroreductase family protein	NA	NA	NA	NA
WP_004198060.1\|52710_53286_+	hypothetical protein	NA	NA	NA	NA
WP_004198061.1\|53245_54529_-	MFS transporter	NA	NA	NA	NA
WP_004534987.1\|54687_55332_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004527819.1\|55669_56293_+	DUF1415 domain-containing protein	NA	NA	NA	NA
WP_004521971.1\|56377_57274_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_017881271.1\|57401_58538_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004521969.1\|58514_58820_+	hypothetical protein	NA	NA	NA	NA
WP_004545603.1\|58894_60013_-	acyltransferase	NA	NA	NA	NA
WP_004545599.1\|60011_60491_+	hypothetical protein	NA	NA	NA	NA
WP_004199982.1\|60450_60954_-	LEA type 2 family protein	NA	NA	NA	NA
WP_017881272.1\|61557_63714_+	peptidase M1	A0A0P0IY26	Acinetobacter_phage	1.9e-46	27.1
WP_004185238.1\|64769_65006_+	hypothetical protein	NA	NA	NA	NA
WP_004204906.1\|65108_65339_+	hypothetical protein	NA	NA	NA	NA
WP_085560611.1\|65954_67223_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004521963.1\|67237_69499_+	peptidase domain-containing ABC transporter	A0A2R8FG22	Brazilian_cedratvirus	2.3e-10	31.9
WP_085560612.1\|69495_70944_+	TolC family protein	NA	NA	NA	NA
WP_004555447.1\|71153_72140_-	hypothetical protein	NA	NA	NA	NA
WP_004199998.1\|72265_73117_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_009967195.1\|73395_77289_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004200003.1\|77285_78275_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004535030.1\|78279_79212_+	OmpA family protein	NA	NA	NA	NA
WP_004521957.1\|79410_80532_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_009967199.1\|80621_83291_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	2.9e-89	32.0
WP_004200010.1\|83324_84425_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004527836.1\|84388_86227_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004204912.1\|86306_86789_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004527837.1\|86846_87350_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004521953.1\|87422_88913_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004521952.1\|88929_89448_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004531875.1\|89484_90156_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004521950.1\|90531_91146_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004521949.1\|91254_92601_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004521948.1\|92597_93383_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_123850113.1\|94719_95193_+	hypothetical protein	NA	NA	NA	NA
WP_004527881.1\|97612_98134_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0

DBSCAN-SWA_2

203156 : 282576

Stx2-converting_phage(27.27%)

transposase,integrase,capsid

attL 199039:199055|attR 275901:275917

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
199039:199055	attL	NA	NA	NA	NA
WP_038802333.1\|203156_204277_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004545968.1\|210457_211732_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_004523130.1\|212358_213357_+	1,2-phenylacetyl-CoA epoxidase subunit A	NA	NA	NA	NA
WP_004551024.1\|213419_213704_+	1,2-phenylacetyl-CoA epoxidase subunit B	NA	NA	NA	NA
WP_004538977.1\|213714_214518_+	phenylacetate-CoA oxygenase subunit PaaC	NA	NA	NA	NA
WP_004551025.1\|214553_215174_+	phenylacetate-CoA oxygenase subunit PaaJ	NA	NA	NA	NA
WP_004525659.1\|215175_216264_+	phenylacetate-CoA oxygenase/reductase subunit PaaK	NA	NA	NA	NA
WP_038714918.1\|216385_217216_+	DUF1835 domain-containing protein	NA	NA	NA	NA
WP_004523127.1\|217242_217842_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_004202737.1\|218084_218732_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004202739.1\|218850_219366_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_085560616.1\|219517_220615_+	4-hydroxyphenylpyruvate dioxygenase	NA	NA	NA	NA
WP_004197901.1\|220850_221048_-	outer membrane protein	NA	NA	NA	NA
WP_004523124.1\|221367_224949_+	indolepyruvate ferredoxin oxidoreductase family protein	NA	NA	NA	NA
WP_038752348.1\|225466_227737_-	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_004197905.1\|228265_228952_+	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	1.2e-15	28.1
WP_004197906.1\|229253_229850_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_004197907.1\|230232_230808_+	flavodoxin family protein	NA	NA	NA	NA
WP_004523123.1\|230960_231905_+	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
WP_004202747.1\|232379_233753_+	DUF2957 domain-containing protein	NA	NA	NA	NA
WP_085560617.1\|233878_235129_+	DUF2957 domain-containing protein	NA	NA	NA	NA
WP_004197912.1\|235148_235979_+	OmpW family protein	NA	NA	NA	NA
WP_004525667.1\|236164_237103_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_017880405.1\|237198_238467_+	MFS transporter	NA	NA	NA	NA
WP_004524369.1\|238556_239225_-	LysE family translocator	NA	NA	NA	NA
WP_004524370.1\|239323_240193_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004525670.1\|240319_241075_+	Mut7-C ubiquitin/RNAse domain-containing protein	NA	NA	NA	NA
WP_004530385.1\|241217_241448_-	hypothetical protein	NA	NA	NA	NA
WP_172408693.1\|241668_242301_-	hypothetical protein	NA	NA	NA	NA
WP_038724390.1\|242536_242908_+	hypothetical protein	NA	NA	NA	NA
WP_004530388.1\|244114_244432_-	hypothetical protein	NA	NA	NA	NA
WP_004533536.1\|244726_244924_-	hypothetical protein	NA	NA	NA	NA
WP_004524380.1\|244946_246353_+	amino acid permease	NA	NA	NA	NA
WP_164978234.1\|246680_247878_+\|transposase	IS3-like element ISButh1 family transposase	A0A1B0Z042	Pseudomonas_phage	3.0e-102	65.2
WP_085560618.1\|248118_250245_-	DUF87 domain-containing protein	NA	NA	NA	NA
WP_085560619.1\|250241_251636_-	SIR2 family protein	NA	NA	NA	NA
WP_009982077.1\|254051_254648_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	6.0e-27	38.1
WP_085504666.1\|254688_256251_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	5.6e-149	53.5
WP_017335489.1\|256280_256628_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	1.2e-40	72.9
WP_009982080.1\|256624_257032_-\|transposase	transposase	B6DZU5	Stx2-converting_phage	1.0e-14	37.2
WP_101610016.1\|256989_257913_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_085560621.1\|258331_260056_-	ATP-binding protein	NA	NA	NA	NA
WP_085560622.1\|260066_261326_-	hypothetical protein	NA	NA	NA	NA
WP_085560623.1\|261600_264243_-	AAA family ATPase	NA	NA	NA	NA
WP_085560624.1\|264239_265370_-	DNA repair exonuclease	NA	NA	NA	NA
WP_085560625.1\|265546_268609_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	6.7e-21	23.2
WP_157129617.1\|268605_268776_-	hypothetical protein	NA	NA	NA	NA
WP_085560626.1\|268762_270142_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_085561020.1\|270138_272529_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_085560627.1\|272634_273138_-	DUF3368 domain-containing protein	NA	NA	NA	NA
WP_085560628.1\|275318_276614_-	restriction endonuclease	NA	NA	NA	NA
275901:275917	attR	NA	NA	NA	NA
WP_085560629.1\|276618_278538_-	AAA family ATPase	K4I1H4	Acidithiobacillus_phage	4.9e-38	32.7
WP_085560630.1\|278989_279475_+	hypothetical protein	NA	NA	NA	NA
WP_085561021.1\|279577_280546_+	DUF932 domain-containing protein	A0A0H4INH5	Stenotrophomonas_phage	1.7e-55	41.0
WP_085560631.1\|280622_281615_+	YqaJ viral recombinase family protein	A6XMH8	Bacillus_virus	1.8e-55	40.6
WP_085560632.1\|281649_282576_+\|capsid	phage capsid protein	NA	NA	NA	NA

DBSCAN-SWA_3

375452 : 386680

Burkholderia_phage(22.22%)

integrase

attL 372657:372674|attR 389251:389268

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
372657:372674	attL	NA	NA	NA	NA
WP_004195754.1\|375452_376097_-	lytic polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	5.7e-07	30.4
WP_085560647.1\|376997_377246_-	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	1.5e-40	96.3
WP_004530408.1\|377402_378482_-	DUF3396 domain-containing protein	A9YX32	Burkholderia_phage	2.2e-160	99.0
WP_009932249.1\|378481_378934_-	VRR-NUC domain-containing protein	Q8W6S1	Burkholderia_virus	2.3e-31	58.8
WP_009932250.1\|379191_379734_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	8.1e-47	55.8
WP_038737733.1\|379987_380905_-	DUF4935 domain-containing protein	A4PE40	Ralstonia_virus	2.3e-46	40.6
WP_009922658.1\|380904_381222_-	helix-turn-helix transcriptional regulator	A0A088CD40	Shigella_phage	6.2e-15	57.0
WP_038710463.1\|381601_382189_-\|integrase	site-specific integrase	A0A0S2SYQ7	Pseudomonas_phage	1.2e-43	50.0
WP_004202928.1\|383370_384270_+	c-type cytochrome	NA	NA	NA	NA
WP_004524472.1\|384592_386680_-	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	1.9e-99	35.8
389251:389268	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1481276 : 1492231

Streptococcus_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004197486.1\|1481276_1483391_-	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_004530837.1\|1483688_1484198_-	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_071810810.1\|1484389_1484608_-	hypothetical protein	NA	NA	NA	NA
WP_004189780.1\|1484870_1485449_-	pseudouridine synthase	NA	NA	NA	NA
WP_004189552.1\|1485716_1486976_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_009929279.1\|1486948_1487131_-	hypothetical protein	NA	NA	NA	NA
WP_004536101.1\|1487143_1488754_+	multicopper oxidase family protein	NA	NA	NA	NA
WP_004196460.1\|1488883_1489087_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|1489619_1489934_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196461.1\|1489930_1492231_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1

DBSCAN-SWA_5

1607905 : 1716126

111

uncultured_Caudovirales_phage(25.0%)

tail,head,lysis,transposase,integrase,coat,capsid,plate,terminase,portal,protease

attL 1628206:1628226|attR 1692512:1692532

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004526328.1\|1607905_1608424_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_172411971.1\|1608797_1609808_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_004522540.1\|1609979_1610795_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004522539.1\|1610977_1611733_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_085560781.1\|1612119_1615104_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_004193185.1\|1615430_1616420_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_004193146.1\|1616419_1618399_+	fused uroporphyrinogen-III synthase HemD/membrane protein HemX	NA	NA	NA	NA
WP_004193604.1\|1618403_1619594_+	heme biosynthesis protein HemY	NA	NA	NA	NA
WP_071810790.1\|1619762_1621070_-	MFS transporter	NA	NA	NA	NA
WP_004522532.1\|1621108_1621867_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_004531967.1\|1621953_1623393_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004522531.1\|1623553_1624081_+	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	9.0e-51	53.8
WP_071810788.1\|1624139_1625066_-	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	2.2e-07	43.1
WP_009969764.1\|1625299_1625914_+	glycoside hydrolase family 3 C-terminal domain-containing protein	NA	NA	NA	NA
WP_009969766.1\|1626077_1627256_-	N-acetyltransferase	NA	NA	NA	NA
WP_009969767.1\|1627376_1629080_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	9.9e-91	36.8
1628206:1628226	attL	NA	NA	NA	NA
WP_004193987.1\|1629140_1629479_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_004191758.1\|1629937_1631026_-	porin	NA	NA	NA	NA
WP_070801033.1\|1631919_1632699_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.3e-17	31.3
WP_004193161.1\|1632721_1633435_-	ABC transporter permease	NA	NA	NA	NA
WP_004522525.1\|1633431_1634121_-	histidine ABC transporter permease HisQ	NA	NA	NA	NA
WP_085560782.1\|1634331_1635108_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011325270.1\|1635502_1636201_+	pirin family protein	NA	NA	NA	NA
WP_004556783.1\|1636547_1637093_-	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004522521.1\|1637334_1638060_+	response regulator	W8CYM9	Bacillus_phage	9.2e-30	35.0
WP_004526345.1\|1638043_1639357_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_004198606.1\|1639430_1639697_-	hypothetical protein	NA	NA	NA	NA
WP_004193300.1\|1639823_1639961_-	hypothetical protein	NA	NA	NA	NA
WP_004534064.1\|1640193_1641951_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_004192968.1\|1642004_1643345_+	nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.2e-32	37.7
WP_004522517.1\|1643730_1644237_-	lipoprotein	NA	NA	NA	NA
WP_004526348.1\|1644233_1644785_-	lipoprotein	NA	NA	NA	NA
WP_004200093.1\|1645073_1645271_+	hypothetical protein	NA	NA	NA	NA
WP_004192381.1\|1645403_1646822_+	alpha,alpha-trehalose-phosphate synthase (UDP-forming)	NA	NA	NA	NA
WP_004522515.1\|1646814_1647417_+	AAA family ATPase	A0A219VHB7	Ochrobactrum_phage	3.3e-25	62.8
WP_004526350.1\|1647589_1648201_-	hypothetical protein	NA	NA	NA	NA
WP_009982343.1\|1648969_1650343_-	MFS transporter	NA	NA	NA	NA
WP_009969852.1\|1650466_1650979_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_004192184.1\|1651552_1651933_-	DUF5594 family protein	NA	NA	NA	NA
WP_004534303.1\|1652090_1652360_+	hypothetical protein	NA	NA	NA	NA
WP_004550750.1\|1652966_1653347_-	hypothetical protein	NA	NA	NA	NA
WP_004522511.1\|1653519_1654059_+\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_009969854.1\|1654156_1655293_-	murein-DD-endopeptidase	NA	NA	NA	NA
WP_004200110.1\|1655549_1655774_-	hypothetical protein	NA	NA	NA	NA
WP_004526357.1\|1656230_1656707_+	hypothetical protein	NA	NA	NA	NA
WP_004538232.1\|1663018_1664239_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	4.6e-239	99.5
WP_123850157.1\|1668914_1669205_+	hypothetical protein	NA	NA	NA	NA
WP_004543927.1\|1669306_1669486_+	hypothetical protein	NA	NA	NA	NA
WP_020850843.1\|1669504_1669729_+	CDI system lipoprotein BcpO	NA	NA	NA	NA
WP_004556790.1\|1669753_1671511_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_004543939.1\|1671543_1671741_+	hypothetical protein	NA	NA	NA	NA
WP_009982077.1\|1671940_1672537_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	6.0e-27	38.1
WP_085504666.1\|1672577_1674140_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	5.6e-149	53.5
WP_017335489.1\|1674169_1674517_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	1.2e-40	72.9
WP_009982080.1\|1674513_1674921_-\|transposase	transposase	B6DZU5	Stx2-converting_phage	1.0e-14	37.2
WP_009964475.1\|1676370_1677471_+\|integrase	site-specific integrase	A0A2D1GMX8	Marinobacter_phage	1.5e-44	31.0
WP_009964477.1\|1677504_1677735_-	hypothetical protein	NA	NA	NA	NA
WP_038720986.1\|1677731_1678511_-	hypothetical protein	Q6J1P0	Burkholderia_virus	6.5e-21	57.3
WP_025405240.1\|1678519_1678849_-	hypothetical protein	NA	NA	NA	NA
WP_009964483.1\|1678962_1680279_-	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_009964485.1\|1680278_1680728_-	hypothetical protein	NA	NA	NA	NA
WP_004534172.1\|1680724_1681330_-	hypothetical protein	NA	NA	NA	NA
WP_004534202.1\|1681326_1681662_-	hypothetical protein	NA	NA	NA	NA
WP_004550209.1\|1681713_1681932_-	hypothetical protein	NA	NA	NA	NA
WP_123850154.1\|1682060_1682516_-	hypothetical protein	NA	NA	NA	NA
WP_009909040.1\|1682463_1682949_-	helix-turn-helix transcriptional regulator	A0A193GYL7	Enterobacter_phage	4.4e-12	41.2
WP_076853252.1\|1683097_1683325_+	hypothetical protein	NA	NA	NA	NA
WP_009927752.1\|1683413_1683941_+	hypothetical protein	C7BGG0	Burkholderia_phage	9.7e-29	46.5
WP_025405238.1\|1683954_1684287_+	hypothetical protein	NA	NA	NA	NA
WP_009964493.1\|1684294_1684750_-	hypothetical protein	NA	NA	NA	NA
WP_099975963.1\|1684751_1685210_+	hypothetical protein	NA	NA	NA	NA
WP_071810769.1\|1685273_1685453_+	hypothetical protein	NA	NA	NA	NA
WP_009964497.1\|1685583_1686054_+	hypothetical protein	NA	NA	NA	NA
WP_009964499.1\|1686175_1688668_+	virulence protein E	A0A2D1GN57	Marinobacter_phage	8.5e-99	41.8
WP_025405237.1\|1688885_1689659_+	hypothetical protein	NA	NA	NA	NA
WP_025405236.1\|1689878_1690067_+	hypothetical protein	NA	NA	NA	NA
WP_009964504.1\|1690160_1690730_+	hypothetical protein	NA	NA	NA	NA
WP_085560785.1\|1690692_1692681_+\|terminase	phage terminase large subunit family protein	A0A2D1GMT1	Marinobacter_phage	1.1e-178	53.3
1692512:1692532	attR	NA	NA	NA	NA
WP_009964508.1\|1692691_1692898_+	hypothetical protein	NA	NA	NA	NA
WP_038720977.1\|1692894_1694388_+\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	4.1e-133	50.8
WP_085560786.1\|1694384_1695461_+\|protease	Clp protease ClpP	A0A2H4JDI2	uncultured_Caudovirales_phage	3.1e-50	38.1
WP_038720978.1\|1695487_1695832_+\|head	head decoration protein	NA	NA	NA	NA
WP_009964517.1\|1695897_1696893_+\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	2.8e-109	59.1
WP_009964519.1\|1696896_1697187_+	hypothetical protein	NA	NA	NA	NA
WP_009964520.1\|1697188_1697719_+\|tail	phage tail protein	A0A2H4JBV1	uncultured_Caudovirales_phage	4.1e-11	29.0
WP_004533675.1\|1697708_1698242_+	hypothetical protein	Q9JML9	Wolbachia_phage	6.2e-23	39.5
WP_038720980.1\|1698244_1698925_+\|plate	phage baseplate assembly protein V	A0A1B2LRU5	Wolbachia_phage	9.0e-19	35.1
WP_009964525.1\|1698989_1699196_+	hypothetical protein	NA	NA	NA	NA
WP_004547840.1\|1699192_1699537_+	GPW/gp25 family protein	A0A2H4JA09	uncultured_Caudovirales_phage	1.4e-23	50.9
WP_009964528.1\|1699533_1700427_+\|plate	baseplate J/gp47 family protein	A0A1J0I2M3	Salmonella_phage	8.4e-49	40.1
WP_004539949.1\|1700419_1700995_+\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	6.0e-32	47.7
WP_004539647.1\|1700982_1702446_+	hypothetical protein	A4JWL8	Burkholderia_virus	8.0e-214	77.8
WP_009964532.1\|1702461_1702914_+\|tail	tail assembly chaperone	A4JWL9	Burkholderia_virus	4.8e-45	77.7
WP_009964534.1\|1702980_1704150_+\|tail	phage tail sheath family protein	A0A2H4J869	uncultured_Caudovirales_phage	3.7e-161	73.5
WP_009964536.1\|1704160_1704664_+\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	1.2e-41	50.0
WP_004533642.1\|1704733_1705036_+\|tail	phage tail assembly protein	V5YST8	Pseudomonas_phage	1.5e-05	37.2
WP_085560787.1\|1705123_1707538_+\|tail	phage tail tape measure protein	A0A2H4JG00	uncultured_Caudovirales_phage	8.0e-62	35.2
WP_085560788.1\|1707546_1708428_+\|tail	phage tail protein	A0A2H4J875	uncultured_Caudovirales_phage	8.6e-30	37.4
WP_025405214.1\|1708402_1708609_+\|tail	tail protein X	A0A2H4J9Z9	uncultured_Caudovirales_phage	2.6e-14	58.2
WP_071810763.1\|1708618_1709671_+	late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	9.2e-79	44.8
WP_004533694.1\|1709746_1709941_+	hypothetical protein	NA	NA	NA	NA
WP_085560789.1\|1709933_1710431_+	lysozyme	A4JX20	Burkholderia_virus	6.9e-69	80.6
WP_009964551.1\|1710430_1710976_+\|lysis	lysis protein	Q8W6S5	Burkholderia_virus	7.3e-80	92.8
WP_085560790.1\|1711119_1711908_+	DNA adenine methylase	Q8W6S4	Burkholderia_virus	6.1e-152	96.9
WP_172411299.1\|1711943_1712645_-	immunity 52 family protein	A4PE26	Ralstonia_virus	8.6e-33	43.7
WP_085539468.1\|1712647_1713250_-	hypothetical protein	NA	NA	NA	NA
WP_172411300.1\|1713591_1714095_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	2.3e-19	40.9
WP_085560791.1\|1714097_1714523_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	4.9e-15	47.0
WP_085539471.1\|1714584_1714866_-	hypothetical protein	NA	NA	NA	NA
WP_085561038.1\|1714862_1715330_-	hypothetical protein	C7BGE3	Burkholderia_phage	6.1e-51	63.0
WP_101610003.1\|1715409_1716126_+	SOS response-associated peptidase family protein	Q8W6R8	Burkholderia_virus	1.4e-110	84.8

DBSCAN-SWA_6

2146229 : 2189580

uncultured_Caudovirales_phage(33.33%)

transposase,coat,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009966471.1\|2146229_2148080_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004546126.1\|2148107_2149523_-	hypothetical protein	NA	NA	NA	NA
WP_004193592.1\|2149546_2149813_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_004192367.1\|2150072_2150300_-	hypothetical protein	NA	NA	NA	NA
WP_038778629.1\|2150333_2153141_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.4e-27	24.7
WP_004535790.1\|2153143_2153977_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_085561045.1\|2154113_2154671_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_009943538.1\|2155389_2155983_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_009970724.1\|2158495_2161831_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_009954547.1\|2163389_2163632_+	hypothetical protein	NA	NA	NA	NA
WP_004521762.1\|2163649_2163955_+	hypothetical protein	NA	NA	NA	NA
WP_085560828.1\|2163967_2166802_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.4e-20	25.9
WP_085560829.1\|2166805_2167822_+	hypothetical protein	NA	NA	NA	NA
WP_085560830.1\|2167824_2170848_+	Fis family transcriptional regulator	NA	NA	NA	NA
WP_004556892.1\|2171284_2171578_+	hypothetical protein	NA	NA	NA	NA
WP_172412005.1\|2173128_2174049_+	hypothetical protein	NA	NA	NA	NA
WP_009966451.1\|2174308_2175622_+	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_162486887.1\|2175764_2176199_+	hypothetical protein	NA	NA	NA	NA
WP_009966448.1\|2176516_2176789_+	hypothetical protein	NA	NA	NA	NA
WP_004525642.1\|2176893_2178114_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	2.7e-239	99.8
WP_004193855.1\|2178354_2178636_-	H-NS histone family protein	NA	NA	NA	NA
WP_009966447.1\|2179103_2180087_-	amidohydrolase family protein	NA	NA	NA	NA
WP_004552892.1\|2180131_2181391_-	MFS transporter	NA	NA	NA	NA
WP_004196705.1\|2181834_2182728_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004531175.1\|2183047_2183269_+	hypothetical protein	NA	NA	NA	NA
WP_004542516.1\|2183526_2184072_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526782.1\|2184124_2184685_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526783.1\|2184761_2185286_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_085560833.1\|2185303_2186143_+	molecular chaperone	NA	NA	NA	NA
WP_172411962.1\|2186187_2188599_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004521738.1\|2188614_2189580_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_7

2268299 : 2275686

Burkholderia_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085560842.1\|2268299_2268635_-	hypothetical protein	A9YWU9	Burkholderia_phage	2.9e-26	84.3
WP_145956524.1\|2268631_2268826_-	hypothetical protein	A9YWV0	Burkholderia_phage	1.1e-19	84.0
WP_157129623.1\|2268822_2268978_-	hypothetical protein	NA	NA	NA	NA
WP_085560843.1\|2268974_2269334_-	hypothetical protein	NA	NA	NA	NA
WP_145956523.1\|2269330_2269591_-	hypothetical protein	NA	NA	NA	NA
WP_085560844.1\|2269602_2269911_-	hypothetical protein	NA	NA	NA	NA
WP_145956522.1\|2269907_2270186_-	hypothetical protein	NA	NA	NA	NA
WP_085560845.1\|2270182_2270665_-	hypothetical protein	NA	NA	NA	NA
WP_085561048.1\|2270657_2271164_-	hypothetical protein	NA	NA	NA	NA
WP_145956521.1\|2271255_2271861_-	hypothetical protein	Q3HQW1	Burkholderia_phage	2.0e-14	44.6
WP_172412004.1\|2271974_2272748_-	phosphoadenosine phosphosulfate reductase family protein	Q6IWS1	Burkholderia_phage	1.1e-86	62.9
WP_085560847.1\|2272710_2273331_-	hypothetical protein	A1YZU8	Burkholderia_virus	1.9e-23	53.0
WP_085560848.1\|2273344_2273653_-	hypothetical protein	NA	NA	NA	NA
WP_085560849.1\|2273671_2273956_-	hypothetical protein	NA	NA	NA	NA
WP_085560850.1\|2273952_2274678_-	HNH endonuclease	NA	NA	NA	NA
WP_085560851.1\|2274690_2275686_-	RNA-directed DNA polymerase	H7BVN7	unidentified_phage	1.1e-41	35.4

DBSCAN-SWA_8

2282692 : 2359622

Burkholderia_virus(21.21%)

tail,integrase,transposase,capsid,plate,portal,terminase,tRNA,head

attL 2299680:2299697|attR 2355525:2355542

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085560863.1\|2282692_2283010_+	hypothetical protein	A1YZR1	Burkholderia_virus	2.1e-34	65.2
WP_085560864.1\|2283019_2283904_+	hypothetical protein	Q8W6P2	Burkholderia_virus	3.7e-89	66.2
WP_085560865.1\|2283900_2284755_+	helix-turn-helix domain-containing protein	A0A1W6JTD5	Pseudomonas_phage	4.9e-30	47.6
WP_085560866.1\|2284759_2285440_+	hypothetical protein	NA	NA	NA	NA
WP_101609992.1\|2285460_2285982_+	DUF1064 domain-containing protein	A4JX56	Burkholderia_virus	7.6e-26	44.6
WP_085560868.1\|2285994_2286336_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_085560869.1\|2286332_2286776_+	DUF1364 family protein	Q3HR02	Burkholderia_phage	1.6e-72	87.8
WP_085560870.1\|2286778_2287111_+	hypothetical protein	Q6JIF6	Burkholderia_virus	1.1e-41	74.1
WP_085560871.1\|2287107_2287347_+	hypothetical protein	A4JX60	Burkholderia_virus	8.0e-15	45.6
WP_085560872.1\|2287346_2287607_+	hypothetical protein	Q6V7S5	Burkholderia_virus	1.3e-15	48.8
WP_085560873.1\|2287632_2288031_+	hypothetical protein	NA	NA	NA	NA
WP_085560875.1\|2288534_2288909_+	DUF2591 family protein	NA	NA	NA	NA
WP_145956516.1\|2288918_2289290_+	hypothetical protein	NA	NA	NA	NA
WP_085560876.1\|2289507_2289711_+	hypothetical protein	NA	NA	NA	NA
WP_085560877.1\|2289707_2290400_+	hypothetical protein	A0A1W6JTE1	Pseudomonas_phage	4.9e-12	28.6
WP_085560878.1\|2290568_2291147_+	hypothetical protein	NA	NA	NA	NA
WP_101609988.1\|2291265_2293161_+\|terminase	phage terminase large subunit family protein	G8EXZ6	Synechococcus_phage	3.0e-136	46.6
WP_085561051.1\|2293202_2293439_+\|head,tail	phage head-tail adapter protein	NA	NA	NA	NA
WP_085560879.1\|2293435_2295091_+\|portal	phage portal protein	A0A291AUL8	Sinorhizobium_phage	8.2e-90	34.7
WP_085560880.1\|2295112_2296009_+	S49 family peptidase	S4TQW3	Salmonella_phage	5.6e-45	44.9
WP_085560881.1\|2296030_2296618_+	hypothetical protein	NA	NA	NA	NA
WP_085560882.1\|2296645_2297059_+\|head	head decoration protein	NA	NA	NA	NA
WP_085560883.1\|2297132_2298179_+\|capsid	major capsid protein	A0A0C5ABI0	Bacteriophage	3.8e-32	30.1
WP_085560884.1\|2298187_2298424_+	hypothetical protein	NA	NA	NA	NA
WP_085560885.1\|2298427_2298772_+	hypothetical protein	NA	NA	NA	NA
WP_145956514.1\|2298764_2299370_+	hypothetical protein	NA	NA	NA	NA
WP_085560887.1\|2299379_2299559_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_085560888.1\|2299555_2301046_+\|tail	phage tail sheath subtilisin-like domain-containing protein	U5P0H3	Shigella_phage	7.6e-103	43.7
2299680:2299697	attL	NA	NA	NA	NA
WP_085560889.1\|2301115_2301490_+\|tail	phage tail tube protein	NA	NA	NA	NA
WP_085560890.1\|2301493_2302054_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_145956513.1\|2302113_2302221_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_085561052.1\|2302217_2303642_+	DNA circularization N-terminal domain-containing protein	U5P4I0	Shigella_phage	5.5e-26	27.2
WP_085560891.1\|2303658_2305308_+\|tail	phage tail protein	NA	NA	NA	NA
WP_172411960.1\|2305370_2306450_+	hypothetical protein	U5P0H6	Shigella_phage	3.0e-24	27.8
WP_085561053.1\|2306491_2307013_+\|plate	phage baseplate assembly protein	Q8W617	Enterobacteria_phage	5.6e-29	41.4
WP_085560893.1\|2307016_2307463_+	phage GP46 family protein	A0A2P9JZK5	Alteromonadaceae_phage	2.2e-21	39.9
WP_085560894.1\|2307464_2308628_+\|plate	baseplate J/gp47 family protein	A0A0C4UQU9	Shigella_phage	6.7e-22	29.7
WP_085560895.1\|2308634_2309231_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_085560896.1\|2309863_2310568_+\|tail	phage tail protein	A9YX14	Burkholderia_phage	2.5e-88	77.4
WP_145956512.1\|2310576_2310768_+	hypothetical protein	NA	NA	NA	NA
WP_085560897.1\|2310764_2311916_-	acyltransferase	C6ZR20	Salmonella_phage	1.6e-12	27.9
WP_085560898.1\|2311919_2312717_-	SGNH/GDSL hydrolase family protein	A0A1P8L663	Pectobacterium_phage	3.6e-11	28.2
WP_009905959.1\|2312839_2313022_+	hypothetical protein	NA	NA	NA	NA
WP_029227429.1\|2313014_2313512_+	lysozyme	Q3HQU9	Burkholderia_phage	1.3e-83	93.3
WP_009905952.1\|2313508_2314054_+	hypothetical protein	NA	NA	NA	NA
WP_085560899.1\|2314050_2314560_+	DUF2514 family protein	Q6J1Q4	Burkholderia_virus	3.6e-57	81.3
WP_085560900.1\|2314520_2315552_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1P9F9	Acinetobacter_phage	3.7e-56	38.8
WP_004193660.1\|2315705_2317019_+	YihY family inner membrane protein	NA	NA	NA	NA
WP_004192500.1\|2317190_2317511_-	DUF962 domain-containing protein	NA	NA	NA	NA
WP_085560901.1\|2317727_2318192_+	CBS domain-containing protein	NA	NA	NA	NA
WP_009937746.1\|2318291_2320226_+	MFS transporter	NA	NA	NA	NA
WP_004534774.1\|2320590_2321700_+	chorismate synthase	A0A291AU41	Pandoravirus	1.1e-82	43.7
WP_085560902.1\|2321867_2323331_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	5.2e-80	38.8
WP_009966388.1\|2323470_2325144_-	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
WP_004192152.1\|2325324_2326104_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004191805.1\|2326148_2326580_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_004536448.1\|2326957_2328031_-	hypothetical protein	NA	NA	NA	NA
WP_004554431.1\|2328959_2330492_-	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_004191840.1\|2331063_2331609_-	PAS domain-containing protein	NA	NA	NA	NA
WP_004192091.1\|2331861_2332566_+	CoA transferase subunit A	NA	NA	NA	NA
WP_004191181.1\|2332567_2333209_+	CoA transferase subunit B	NA	NA	NA	NA
WP_085560903.1\|2333633_2334356_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_045597370.1\|2334399_2335500_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_004526835.1\|2335514_2336072_-	ester cyclase	NA	NA	NA	NA
WP_004192063.1\|2336259_2337165_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_024431237.1\|2337190_2338093_+	hypothetical protein	NA	NA	NA	NA
WP_011832186.1\|2338260_2339397_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004526838.1\|2339470_2339824_+	RidA family protein	NA	NA	NA	NA
WP_004205973.1\|2339868_2342106_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	NA	NA	NA	NA
WP_004191232.1\|2342564_2344472_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.7e-123	37.5
WP_071810680.1\|2344521_2345046_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	4.1e-11	28.7
WP_004191477.1\|2345238_2345436_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_004192938.1\|2345466_2345826_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_004534778.1\|2345974_2346988_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	3.5e-27	39.3
WP_004526839.1\|2347075_2349508_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_004526840.1\|2349580_2349985_+	integration host factor subunit alpha	A0A1P8CWT5	Bacillus_phage	2.8e-12	41.1
WP_004526841.1\|2350043_2350448_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_009966381.1\|2350569_2352690_-	hypothetical protein	NA	NA	NA	NA
WP_004535480.1\|2353189_2354374_-	acyltransferase	A0A166XZF2	Gordonia_phage	4.4e-13	28.4
WP_009966380.1\|2355075_2356278_-	DUF3443 domain-containing protein	NA	NA	NA	NA
2355525:2355542	attR	NA	NA	NA	NA
WP_009930627.1\|2356288_2356780_-	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_004531206.1\|2357130_2358336_+	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_004525642.1\|2358401_2359622_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	2.7e-239	99.8

DBSCAN-SWA_9

2989450 : 2995069

Burkholderia_virus(57.14%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164978234.1\|2989450_2990648_+\|transposase	IS3-like element ISButh1 family transposase	A0A1B0Z042	Pseudomonas_phage	3.0e-102	65.2
WP_004531416.1\|2990857_2991085_-	hypothetical protein	Q8W6S4	Burkholderia_virus	3.8e-22	75.8
WP_004557051.1\|2991338_2991734_+	hypothetical protein	NA	NA	NA	NA
WP_028200808.1\|2992014_2992437_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	9.2e-14	48.3
WP_028200809.1\|2992433_2992940_+	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	1.0e-19	40.9
WP_071810609.1\|2993281_2993884_+	hypothetical protein	NA	NA	NA	NA
WP_009920998.1\|2993890_2994616_+	immunity 52 family protein	A4PE26	Ralstonia_virus	5.8e-32	44.0
WP_076833215.1\|2994636_2994822_-	hypothetical protein	Q8W6S4	Burkholderia_virus	4.4e-21	85.2
WP_004196630.1\|2994805_2995069_-	hypothetical protein	Q8W6S4	Burkholderia_virus	2.2e-26	85.5

DBSCAN-SWA_10

3511973 : 3520790

Tanapox_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004535490.1\|3511973_3512816_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	1.4e-16	26.6
WP_004522362.1\|3513154_3514078_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	2.4e-43	36.2
WP_038757350.1\|3514256_3515540_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004550116.1\|3515766_3516669_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	3.3e-53	39.9
WP_004189725.1\|3516994_3517312_-	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_004537712.1\|3517383_3518376_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_009921652.1\|3518434_3519358_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	27.1
WP_004537711.1\|3519389_3520790_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	4.2e-79	38.5

DBSCAN-SWA_11

3898586 : 3907843

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_028201128.1\|3898586_3900134_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004194373.1\|3900170_3900698_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004532195.1\|3900694_3901378_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.0e-05	26.0
WP_004194137.1\|3901442_3902258_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_028201129.1\|3902441_3904460_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	7.0e-51	34.2
WP_004522147.1\|3904493_3905624_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.7e-22	27.6
WP_004533561.1\|3905890_3907843_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP018419

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018419_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018419_1

606998-608317

Orphan

Consensus_repeat	Method
CCCGTNGCCGTGCTNNNN	CRT

31 spacers

The CRISPR arrays of NZ_CP018419_1

>merge|NZ_CP018419|1|606998-608317|CRT
CCCATCGCCGTGCTCGATTCACCCGACGCGGTAGCATCCTGGCCCGTTGCCGTGCTGTTGTTCCCCGTTGCTTGCGAACCTTGGCCCGTCGCCGTGCTCGATTCACCCGACGCGTTAGCATCCTGCCCCGTTGCCGTGCTGTTGCTGCCCGTCGCTTGCGAGCCTTGGCCCATCGCCGTGCTCGATTCACCCGACGCGGTGGCATCCTGCCCCGTTGCCGTGCTTGATGTGCCCGACGCGGTGGCATCCTGACCCGTTGCCGTGCTGTTGTTCCCCGTCGCTTGCGAGCCTTGGCCTGTCGCCGTGCTCGATTCACCCGACGCGTTAGCATCCTGCCCCGTTGCCGTGCTGTTGCTGCCCGTCGCTTGCGAACCTTGGCCCGTCGCCGTGCTCGATGTGCCCGACGCGGTGGCATCCTGGCCCGTTGCCGTGCTGTTGCTGCCCGTCGCTTGCGAGCCTTGGCCCATCGCCGTGCTCGATTCACCCGACGCGGTGGCATCCTGCCCCGTTGCCGTGCTGTTGCTGCCCGTCGCTTGCGAACCTTGGCCCATCGCCGTGCTCGATTCACCCGACGCGGTGGCATCCTGCCCCGTTGCCGTGCTGTTGCTGCCCGTCGCTTGCGAACCTTGGCCCATCGCCGTGCTCGATTCACCCGACGCGGTGGCATCCTGCCCCGTTGCCGTGCTGTTGTTCCCCGTCGCTTGCGAACCTTGGCCCGTTGCCGTGCTCGATGTGCCCGACGCGGTGGCATCCTGACCCGTTGCCGTGCTGTTGTTCCCCGTCGCTTGCGAACCTTGGCCCGTTGCCGTGCTCGATGTGCCCGACGCGGTGGCATCCTGACCCGTTGCCGTGCTGTTGTCCCCCGTCGCTTGCGAGCCTTGGCCCGTTGCCGTGCTGTTGCTGCCCGTCGCTTGCGAGCCTTGGCCCGTCGCCGTGCTCGATTCACCCGACGCGGTAGCACCCTGGCCCGTTGCCGTGCTGTTGTCCCCCGTCGCTTGCGAACCTTGGCCCGTCGCCGTGCTCGATTCACCCGACGCGGTAGCACCCTGGCCCGTTGCCGTGCTGTTGTCCCCCGTCGCTTGCGAACCTTGGCCCGTCGCCGTGCTCGATTCACCCGACGCGGTGGCATCCTGCCCCGTTGCCGTGCTGTTGCTGCCCGTCGCTTGCGAACCTTGGCCCGTCGCCGTGCTCGATGCACCCGACGCAGTGGCATCCTGACCCGTTGCCGTGCTGTTGCTACCCGTCGCATGCGAGCCTTGGCCCGTTGCCGTGCTATGACTGCCCGTCGCCTGCGCACCGTTACCCAGTGCGGTGCTTTGC

>NZ_CP018419|1|1|606998-608317|CRT
CCCATCGCCGTGCTCGAT	TCACCCGACGCGGTAGCATCCTGG
CCCGTTGCCGTGCTGTTG	TTCCCCGTTGCTTGCGAACCTTGG
CCCGTCGCCGTGCTCGAT	TCACCCGACGCGTTAGCATCCTGC
CCCGTTGCCGTGCTGTTG	CTGCCCGTCGCTTGCGAGCCTTGG
CCCATCGCCGTGCTCGAT	TCACCCGACGCGGTGGCATCCTGC
CCCGTTGCCGTGCTTGAT	GTGCCCGACGCGGTGGCATCCTGA
CCCGTTGCCGTGCTGTTG	TTCCCCGTCGCTTGCGAGCCTTGG
CCTGTCGCCGTGCTCGAT	TCACCCGACGCGTTAGCATCCTGC
CCCGTTGCCGTGCTGTTG	CTGCCCGTCGCTTGCGAACCTTGG
CCCGTCGCCGTGCTCGAT	GTGCCCGACGCGGTGGCATCCTGG
CCCGTTGCCGTGCTGTTG	CTGCCCGTCGCTTGCGAGCCTTGG
CCCATCGCCGTGCTCGAT	TCACCCGACGCGGTGGCATCCTGC
CCCGTTGCCGTGCTGTTG	CTGCCCGTCGCTTGCGAACCTTGG
CCCATCGCCGTGCTCGAT	TCACCCGACGCGGTGGCATCCTGC
CCCGTTGCCGTGCTGTTG	CTGCCCGTCGCTTGCGAACCTTGG
CCCATCGCCGTGCTCGAT	TCACCCGACGCGGTGGCATCCTGC
CCCGTTGCCGTGCTGTTG	TTCCCCGTCGCTTGCGAACCTTGG
CCCGTTGCCGTGCTCGAT	GTGCCCGACGCGGTGGCATCCTGA
CCCGTTGCCGTGCTGTTG	TTCCCCGTCGCTTGCGAACCTTGG
CCCGTTGCCGTGCTCGAT	GTGCCCGACGCGGTGGCATCCTGA
CCCGTTGCCGTGCTGTTG	TCCCCCGTCGCTTGCGAGCCTTGG
CCCGTTGCCGTGCTGTTG	CTGCCCGTCGCTTGCGAGCCTTGG
CCCGTCGCCGTGCTCGAT	TCACCCGACGCGGTAGCACCCTGG
CCCGTTGCCGTGCTGTTG	TCCCCCGTCGCTTGCGAACCTTGG
CCCGTCGCCGTGCTCGAT	TCACCCGACGCGGTAGCACCCTGG
CCCGTTGCCGTGCTGTTG	TCCCCCGTCGCTTGCGAACCTTGG
CCCGTCGCCGTGCTCGAT	TCACCCGACGCGGTGGCATCCTGC
CCCGTTGCCGTGCTGTTG	CTGCCCGTCGCTTGCGAACCTTGG
CCCGTCGCCGTGCTCGAT	GCACCCGACGCAGTGGCATCCTGA
CCCGTTGCCGTGCTGTTG	CTACCCGTCGCATGCGAGCCTTGG
CCCGTTGCCGTGCTATGA	CTGCCCGTCGCCTGCGCACCGTTA
CCCAGTGCGGTGCTTTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018419.1\|WP_028201534.1\|610001_611459_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018419.1\|WP_004523720.1\|616658_616985_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP018419.1\|WP_085561118.1\|596050_597727_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP018419.1\|WP_004549711.1\|603804_604359_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|284781
NZ_CP018419.1\|WP_009967413.1\|614201_614909_+\|DUF2244-domain-containing-protein	unknown	unknown	gnl\|CDD\|378350
NZ_CP018419.1\|WP_004533867.1\|602674_603220_-\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP018419.1\|WP_009981081.1\|599015_601712_-\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|225729
NZ_CP018419.1\|WP_004545009.1\|604656_606108_+\|PhoPQ-regulated-protein	unknown	unknown	gnl\|CDD\|226737
NZ_CP018419.1\|WP_004523721.1\|617004_617424_+\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|223509
NZ_CP018419.1\|WP_009967412.1\|615494_616187_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018419.1\|WP_004529635.1\|601872_602595_-\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|236634
NZ_CP018419.1\|WP_004533827.1\|612151_612355_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018419.1\|WP_025986099.1\|598450_599023_-\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP018419.1\|WP_045597630.1\|617838_618102_-\|PAAR-domain-containing-protein	unknown	unknown	gnl\|CDD\|269829
NZ_CP018419.1\|WP_004523700.1\|595133_595673_-\|type-VI-secretion-system-contractile-sheath-small-subunit	unknown	unknown	gnl\|CDD\|226047
NZ_CP018419.1\|WP_004523708.1\|604369_604585_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018419.1\|WP_153260193.1\|609297_609657_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018419.1\|WP_045597629.1\|618111_619770_-\|DUF2875-family-protein	unknown	unknown	gnl\|CDD\|288282
NZ_CP018419.1\|WP_004537300.1\|597729_598419_-\|DotU-family-type-IV/VI-secretion-system-protein	unknown	unknown	gnl\|CDD\|378275
NZ_CP018419.1\|WP_004523716.1\|612609_614205_+\|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|238833

Protein	Function_ID	Function_description	E-value
NZ_CP018419.1\|WP_045597630.1\|617838_618102_-\|PAAR-domain-containing-protein	gnl\|CDD\|269829	cd14744, PAAR_CT_2, proline-alanine-alanine-arginine (PAAR) domain with uncharacterized C-terminal extension. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family of mostly beta- and gamma-proteobacteria, and forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). Most members contain C-terminal domain extensions corresponding to several uncharacterized domains such as S-type pyocin, DUF2235, DUF2345 and cytotoxic proteins. However, these terminal domains are exposed to solution, and do not distort the binding site of VgrG. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes.	1.57078e-23
NZ_CP018419.1\|WP_004523720.1\|616658_616985_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	5.63925e-18
NZ_CP018419.1\|WP_085561118.1\|596050_597727_-\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	5.7584e-35
NZ_CP018419.1\|WP_004549711.1\|603804_604359_+\|hypothetical-protein	gnl\|CDD\|284781	pfam07437, YfaZ, YfaZ precursor. This family contains the precursor of the bacterial protein YfaZ (approximately 180 residues long). Many members of this family are hypothetical proteins.	1.94915e-11
NZ_CP018419.1\|WP_009967413.1\|614201_614909_+\|DUF2244-domain-containing-protein	gnl\|CDD\|378350	pfam10003, DUF2244, Integral membrane protein (DUF2244). This domain, found in various bacterial hypothetical and putative membrane proteins, has no known function.	1.60511e-36
NZ_CP018419.1\|WP_004533867.1\|602674_603220_-\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	6.50534e-21
NZ_CP018419.1\|WP_009981081.1\|599015_601712_-\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP018419.1\|WP_004545009.1\|604656_606108_+\|PhoPQ-regulated-protein	gnl\|CDD\|226737	COG4287, PqaA, PhoPQ-activated pathogenicity-related protein [General function prediction only].	0
NZ_CP018419.1\|WP_004523721.1\|617004_617424_+\|YjbQ-family-protein	gnl\|CDD\|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	1.018e-53
NZ_CP018419.1\|WP_025986099.1\|598450_599023_-\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	2.14812e-22
NZ_CP018419.1\|WP_004523700.1\|595133_595673_-\|type-VI-secretion-system-contractile-sheath-small-subunit	gnl\|CDD\|226047	COG3516, COG3516, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	7.24528e-84
NZ_CP018419.1\|WP_004529635.1\|601872_602595_-\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|236634	PRK09926, PRK09926, fimbrial chaperone.	6.76191e-96
NZ_CP018419.1\|WP_045597629.1\|618111_619770_-\|DUF2875-family-protein	gnl\|CDD\|288282	pfam11394, DUF2875, Protein of unknown function (DUF2875). This family of proteins with unknown function appear to be restricted to Proteobacteria.	0
NZ_CP018419.1\|WP_004537300.1\|597729_598419_-\|DotU-family-type-IV/VI-secretion-system-protein	gnl\|CDD\|378275	pfam09850, DotU, Type VI secretion system protein DotU. DotU is a family of Gram-negative bacterial proteins that form part of the membrane-joining complex of the type VI secretion system. DotU binds tightly to IcmF and together they are tethered to the inner membrane at one end and the peptidoglycan layer at the other; they interact with Lip1 which then tethers the peptidoglycan layer to the outer membrane.	2.62288e-29
NZ_CP018419.1\|WP_004523716.1\|612609_614205_+\|cytochrome-c-oxidase-subunit-I	gnl\|CDD\|238833	cd01663, Cyt_c_Oxidase_I, Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of prokaryotes. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits varies from three to five in bacteria and up to 13 in mammalian mitochondria. Only subunits I and II are essential for function, but subunit III, which is also conserved, may play a role in assembly or oxygen delivery to the active site. Subunits I, II, and III of mammalian CcO are encoded within the mitochondrial genome and the remaining 10 subunits are encoded within the nuclear genome. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme (heme a3) and a copper ion (CuB). It also contains a low-spin heme (heme a), believed to participate in the transfer of electrons to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from cytochrome c on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are transferred from cytochrome c (the electron donor) to heme a via the CuA binuclear site in subunit II, and directly from heme a to the binuclear center.	0

>NZ_CP018419.1|WP_004545009.1|604656_606108_+|PhoPQ-regulated-protein
MLSLAYPRAEAAPIAFPCPIDARRDLTDTLACYRQTVENQPLNYTMTGIVQLPGIEQRTYRLVSQSWSPDQLVRPDTWVHEVALYIPQDALPRRALVIANDGTRHPGEGETPRTPNDFLPDTLADIARSTRTAVISVSDVPNQLLSYADDGKPKAEDDSVARSWTLFMQSPHTRGAMPLHVPMAASIWRAMSLAERELTSLGIHRFVVSGISKRAWTTWLALIGDQRVDAIAPFAIDLLSTRAALENMYRSYGGNWPLAFYPYYAEGIDRTLDSPAFGLLMRIEDPLSYLGTRHGSRLAVPKYIVNASGDDFFVPDNSQRYFDKLPGAKALRMVPNSSHSDIRRATLDSLVPFVKRIQHGKALPQVDAAPIETNGQTILRLRTSERPRQLLLWQATNPLARDFRYACGIRYTSTPIAMNGARPQQLVLVPPTNGWRAYFVEATFDDGFVATSQTYILGDGYPSTSPPAVGGSCRTLLGRDTHS
>NZ_CP018419.1|WP_004523708.1|604369_604585_-|hypothetical-protein
MAIVGEPPEELIDRLLRACRPLAPILPIAPMPQAKRRDERRVLQGKTWREMHRALVPFDRRTIQKEKPAAR
>NZ_CP018419.1|WP_004549711.1|603804_604359_+|hypothetical-protein
MSRTESSIFAKRSDWPRVFSKLGLVASSIGVFAFMPNARASDYSIAIGNGYQSVSRTPTGTGFGFLLDATRSGEDAYSIGSGLSSGVRIGAVSLTVAGKALHVRSADDRSGLTTPVGVIAGIPAASRLSLVARAFYTPRAVFNAALGAYTQATAGVRWTYKPINLEAGWRYEALKGRNGTRDPR
>NZ_CP018419.1|WP_004533867.1|602674_603220_-|type-1-fimbrial-protein
MKKKVVSFAVATLFGLVAAQSVYAQSIDQGQVKFTGELTANTCTIDAGSKDQIVPLPKVSTSALAAPGDVAGSTAFEIKVSKCAADVKKVAAHFEMENMDPNTRTLKNEATGADAATNVTIQLVNSDGTELPVGSTGSYFDVTGTDDARGATMIYGGQYYALDTTTAGKVESHTLFTLAYE
>NZ_CP018419.1|WP_004529635.1|601872_602595_-|fimbria/pilus-periplasmic-chaperone
MCVAVAAACCLASTLSQAAIVITGTRVVYPESSREVNVRLNNVEQSPVLVQAWIDDGNAGASPDEIKVPFVLMPPVFRVEPKKGQTLRVMYTGDDLPKDRESVYWLNVLEIPPKPTVEAEQNLLQLAFRTRIKLFFRPSALEDGNAAQARDQLKWKIVRNEKGVSVLRAENRSPYYISISQATAKSGDKSVQFDPGMVPPFGSKEFVSKHDISTLSTHAEIAYKLLNDYGAEVAGSATAE
>NZ_CP018419.1|WP_009981081.1|599015_601712_-|fimbrial-biogenesis-outer-membrane-usher-protein
MPVVAAEFDGTRTGEQSRPDAMGEAPSGAEPGTRGRQALLVASHASPSAPTTVSFNSRLLMGGGIDLSRFERGNPVVAGIYPVDVTVNGERRGRMDVEFRDVRGGDSAAPCFTRAMLDRLGVEGDIVAKRLDAARDATGAASGQTPTLSASACIGLRDALPDATYTLDSADLTLDLTIPQVDMRKTARGYVDPSRWDNGVNAGLLQYNLSGYASENKFFGNHASSLFLGLQAGANIGAWRVRQRSNLMWANRSAGMSWRSLETYVQRDITALRSQITLGDSYTTGEIFESFGVRGMQLASDDRMLPVSLQSYAPTVRGVADTNARVAVRQRGNVIYEASVPPGPFEFDDLPPTGYGGDLDVTITESDGRTKHFTVPFASVRQLLRPGMQRFNFTVGQYRDALSNGKPWVAQLTYQRGMTNLLTGYAGLLSSTGYASGLIGVALNTPIGAFAFDVTSARTHLPGQGARNGFSSHLSYSKMVPSTGTHFSMAAYRYSTANYYSLADAVTARYGYNAEERAWRNDYRARTRLQLNVNQRIGDRSSAYVSSSLLNYWDGRGRDIQFQAGFSSVFKRVSYTVYAQRSRSSDDRTVTQVGVNLSIPLGSGAYTKRNAFSSLTTSLSRASNGDSSIQANLSGSTAHVVPIDYGVNVSRSVTGDSNFASLGVYGTYRSPFGTYSGNASVDNRARQASFGANGAVVLHRGGVTLSPPLGSAAALVEAKGARGGKLINGQGATIDRFGYAVIPSLMPYRANTVAIDPSELPDDVELANTSEEVVPRNNSIVFVKMETKRGRPVFAATETEDGKPLPMGSELFDVEGKSLGGVGQGGMAFLRGLQGAGNVVAKWGAGASEQCTMPYLVPADQAQAKQSRAIVRIRLRCEPRLSADASQTPRGDGGTRND
>NZ_CP018419.1|WP_025986099.1|598450_599023_-|type-1-fimbrial-protein
MIEMNGLKFRRGAARRWPSIAAAAMFAASAACGAPPSPTVTIKFKGSYNPVTCTVVEGNENKTVHLPTISTSSLANAGETAGATGFDISVLCDGYAGNVLAYFENGPTTNENGNLDVEDPSDGQSASGVQVQLLNGDGSPIKVGDISTMKTVSVEASTPMPIPFFARYYATGKSGAGKVRTYVTFVIQML
>NZ_CP018419.1|WP_004537300.1|597729_598419_-|DotU-family-type-IV/VI-secretion-system-protein
MSIEMPAQPLRMLLQDTMLHVALLTQGARISRVHDWRARCIALVRQFEQALQDGGYRGGIANELGLAQCVFLDEITMRNLSTEQKEEWLRELLQFRFHSIRDGLSKVRARIDRLCRGHSANAALLEMYSLFHEFGLLGDKQGHALADARVSEARPTPGKKAVETAEIWKDGGAANEAAHGRSWRIVGGLLAFAALMTMWLVIDTRLSHEVEQMEVTSGDEAAIHPASGD
>NZ_CP018419.1|WP_085561118.1|596050_597727_-|OmpA-family-protein
MSRQIRFWLVWGAIPFVVLASLCLPLRMQPEWSHVLTIVLIIAAIVLAIEIFEHSRETAQDRTAEAEIDDHELAVIIVAGPHASSLFNSSGDDTAFRREAGALWLRADSVEQLRDTMMRVKASRGRFPDAAVVPLVSESDDESDMRQAFAKWRTELREALCYPDAAYVLPCYLAVYTCLGFKGADGARPKWTGDAIEIGTRQMNAALKVGELLASIRQQLLRPSPTGSSAQCALGLGVFDWLDATALLSSMTMLANTPPFMLKGLTLADVGRRPIRPGAWTRWLTVRTGLHIRQTKSSMAPLPVPRVAKHAESGIREGWSSARHLVSTRASFVPALVFSTVSTLGIAVAVSGWMNSRMIQRVSNDIADYRSGADEWIGRKRFAQARLEHDRTAIVQTLLDGVPTGFGWGLYRGQELLVKLDTVLDSPRTASIAMQLDTVSLFAAGKATFSPGAAQRELQHALRMILANPEQRVLIVGHADSSGSDAANFQLSEARARAIRDWFVDQGVLKTRFIVQGAGDTHPIADNDSPSGRAQNRRVEVLLIPDVSSDRKASGTEL
>NZ_CP018419.1|WP_004523700.1|595133_595673_-|type-VI-secretion-system-contractile-sheath-small-subunit
MAISNSSQKFIARNRAPRVQIEYDVEIYGSEKKVELPFVMGVLADLSGKPLEPLPAVGDRKFFSIDIDNFDERMKAMKPRVAFSVPNTLSGDGQLMVDITFESMDDFSPAAIAKKVDALSQLLDARTQLANLQTYMDGKSGAENLVSKVLKDPALLSALAKAPKPVAEQAENRESKEKH
>NZ_CP018419.1|WP_153260193.1|609297_609657_+|hypothetical-protein
MMNTPLSTRSTNFNSLVHRLTARLHALVTTRNSSGLLAWKTRDELERLLPAGTPMTHVGWRLGPPHQAVEYPGGCVTWIFLSNGQWLREPGRLLMWSAQTRSLRLTFDREQILTQMQLD
>NZ_CP018419.1|WP_028201534.1|610001_611459_+|hypothetical-protein
MPIRQTHIWIFGFMIACVLAMSGPLTYTFENTFQQTVDIDRKKQGTVAEATAFDARSAEQPSAPDADRMHELPRIDAARSPTDHFDELPIHLAAFGGGEPSPSGPLPPGPLPDTSFAPFPFQHGFDTAIHAGPPIPAPPESTLARTDAPPRDETPFEPGMPQPSETVDTQLSFYADMVAQAIERTAYDSIALAKLDSDTTAPPDLTPERHGALANVNAPMFYADMLTASIHVPPSNDHTLSVPSLLTHQAIGIAWMELFARELPATATQAAPTRHAVSFAATLQAEPFDLAQWSEPDEAHSDGPPLELDGQRTIAPPYPRAGTLPPGTRPTYTDSPPDTGIVQAAAMLATGFESAGKHAAALRGQPPGADECRMGARAIGLGRSGMERLAIEQLVSSARAAYDCARARIHGRATAFANAPASAQPSNHLDANGDPMRIAFLPRLASEPFQEAFSIPGDTAGIASAFAVADDQTGHRNRMAAANSD
>NZ_CP018419.1|WP_004533827.1|612151_612355_+|hypothetical-protein
MADTPQTGATHAFLSARIASNSSKKTFVRRPLGGTRTALSRTGAVNCFTIFHAICCLRRLAARINLG
>NZ_CP018419.1|WP_004523716.1|612609_614205_+|cytochrome-c-oxidase-subunit-I
MSEISTNMPHVRDAAHHAPTGWRRWLFATNHKDIGTLYLLFSIVNLMIGGVMALMIRAELFEPGLQLMRPEFFNQLSTEHGFIMIFGAIMPAFVGLANWMIPLQIGASDMAFARMNNFSFWLLPVSSALLIGSFFVPGGAPAAGWTMYAPLSTQMGPGMDLSIFAIHIAGASSIMGAINIVVTVVNMRAPGLTLMKMPMFAWTWIITSFLLIAIMPVLAGAVTMVLFDRHFGTSFFNASGGGDPVLYQHIFWYFGHPEVYVMILPGFGMISQVIPAFSRKPLFGYASMVYATASIGILSFMVWAHHMFVTGMPVAGQLFFMYATMTIAVPTGVKVFNWVATMWRGSLTFETPMLFSIGFIFVFLIGGLTGVTLAMAPLNVALHGTYYIIAHFHYVMVAASLFSIYAGWYFWVPKWTGYFYDERRGRIHFWGSMISFNVTFFPMHFLGLAGMPRRYADYPAQFTDFNQIATIGAFAFGLMQVYFLFWVALPTYLGKTRRCVDAKPWDGAQGLEWTLPSPAPYHSFETPPAVK
>NZ_CP018419.1|WP_009967413.1|614201_614909_+|DUF2244-domain-containing-protein
MTARPRTRRHARAHADAGANANADADVNMKADARCDTRKHAQRHCTPAFVAHDPRLMTRDVAENRRVWLLKRNCALSPRQSLISMGLLAALTLAIAMPFAIAGAWAVFACAIGEIAAMCGCFLLYARHAVDYDCVALTEQRLEVVQCDGAQLRRYDWNPLWVAVDLDAAHARDPTIRIRHGSETVLVGRHVTLARRRHVAGELNAALAASAGDFGDTDFAPSVRQRQPEPLAAHR
>NZ_CP018419.1|WP_009967412.1|615494_616187_-|hypothetical-protein
MNSQHARFIRPVLGTLCIVSLAALSGCRGDACFGFDGCFDDGGVQTVTLSGTAATGPALASATVNVDCARGSVATLSDGGGHYSVTFDAALPCAITVTSGGTSLHSLAYAGGTFNTTPQTELLLVYLAAQLGTSPARLIGDLPNSSRLQQALENQTNVQAAQTAVVANLQQRYAVMFAVPEFLTTPFFVGQPGVDGDLGVLANAGAIDANGMPDALAVSLLQQAGAAHPL
>NZ_CP018419.1|WP_004523720.1|616658_616985_+|thioredoxin-family-protein
MHSSQAYTADAPTRAEVDALAGATVIEFGANWCGICAGAQPAIRDAFSVHADVRHLKIEDGPGRPLGRSFGIKLWPTLVFLRDGTEVARVVRPTHAEQIETIGFAALV
>NZ_CP018419.1|WP_004523721.1|617004_617424_+|YjbQ-family-protein
MQQSIQHITVEARGRGLVEFTPQVRAFVEVQSVSTGLLTVFCRHTSASLLIQENADPSVQRDIERYFAALAPEDDARYEHDTEGADDMPAHLRTALTQVQLSIPVEHGRMVLGTWQGIYLFEHRRAPHRRDVVLHLIGE
>NZ_CP018419.1|WP_045597630.1|617838_618102_-|PAAR-domain-containing-protein
MRGVIRIGDSTSHGGRVETGREGSTVMGRAVARVGDRCTCPMNGHEHCVIVEGDEDVRIEGRAVAFDGHRTSCGATLVSSMPTSGRV
>NZ_CP018419.1|WP_045597629.1|618111_619770_-|DUF2875-family-protein
MKPRIWPYALGFILMALGWTIVVMARHYHYWQATGQEMPGMVSSIRNGVLVALGVVAAAFTASYFWLHSGSAESAPAATGTASTAPTRSAMDPSENNGASALLAQSGGKFVLEVRGLGLVTGKETNEEIWKAIETKADNHSTYMSQNSADYPANEDERMTEVGLSTRISFKYGARHSVEYWPVPVFIWEPPKASHVSRPANELSGIRQEASLGVTLLLWQEDANTNDGSTIIEKLFAFFDAHPDIPEAIIVTFDGAATRDLNQTPGYVDTFKQSNIPTMPDSMVTLLVSRSDRVDRLIRPYAVEQTENVDKNTTEYDITKLWNFFWEKNNGEGPGSFEAYYQEQQKAAGIQPRAFLGFMSAQWWQTQLPDFWKTISNKGPGEFKPTPYIPVRWTTWQVRQFDNAPLLGYLHRPIDVKLADAHGKPLKTAQQVQALKAGWQQAVDTLPTGETPKRIFYDTTGDRAWVAPINQALAQSGPSAPSLDDVKEGYDIGRRIGNTGISSPLVQIGLGLIASYHEGGASATIHRRPNGTATIVMVSPPTHKQPDVNPFR

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Crispr_ID: NZ_CP018419_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018419_2

1202523-1202615

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGCCGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018419_2

>merge|NZ_CP018419|2|1202523-1202615|CRISPRCasFinder
TCGCCGCCGCGCGCGCCGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NZ_CP018419|2|1|1202523-1202615|CRISPRCasFinder
TCGCCGCCGCGCGCGCCGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018419.1\|WP_085503029.1\|1200568_1201060_+\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NZ_CP018419.1\|WP_085561162.1\|1213885_1217116_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP018419.1\|WP_004524990.1\|1208816_1210382_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP018419.1\|WP_085561161.1\|1206120_1207146_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NZ_CP018419.1\|WP_172411934.1\|1191721_1193008_+\|hexose-kinase	unknown	unknown	gnl\|CDD\|238570
NZ_CP018419.1\|WP_004187193.1\|1202055_1202304_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NZ_CP018419.1\|WP_004552097.1\|1212758_1213883_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NZ_CP018419.1\|WP_004187346.1\|1201357_1202059_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NZ_CP018419.1\|WP_009982027.1\|1200116_1200572_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NZ_CP018419.1\|WP_004524980.1\|1194912_1196316_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NZ_CP018419.1\|WP_004188840.1\|1196326_1198120_-\|polyhydroxyalkanoic-acid-synthase	unknown	unknown	gnl\|CDD\|213656
NZ_CP018419.1\|WP_085561159.1\|1198480_1200127_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NZ_CP018419.1\|WP_045597583.1\|1207205_1207709_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018419.1\|WP_071811430.1\|1210773_1212609_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP018419.1\|WP_004529184.1\|1193737_1194916_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NZ_CP018419.1\|WP_009969306.1\|1217112_1218186_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|235136
NZ_CP018419.1\|WP_009969313.1\|1207766_1208276_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018419.1\|WP_058040623.1\|1203050_1205057_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NZ_CP018419.1\|WP_004524985.1\|1201052_1201361_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NZ_CP018419.1\|WP_004533337.1\|1205053_1205902_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304

Protein	Function_ID	Function_description	E-value
NZ_CP018419.1\|WP_085503029.1\|1200568_1201060_+\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	4.40024e-17
NZ_CP018419.1\|WP_085561162.1\|1213885_1217116_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.89663e-92
NZ_CP018419.1\|WP_004524990.1\|1208816_1210382_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.47951e-79
NZ_CP018419.1\|WP_085561161.1\|1206120_1207146_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.0252e-180
NZ_CP018419.1\|WP_172411934.1\|1191721_1193008_+\|hexose-kinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	2.23891e-109
NZ_CP018419.1\|WP_004187193.1\|1202055_1202304_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37
NZ_CP018419.1\|WP_004552097.1\|1212758_1213883_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.904e-25
NZ_CP018419.1\|WP_004187346.1\|1201357_1202059_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NZ_CP018419.1\|WP_009982027.1\|1200116_1200572_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	7.97553e-62
NZ_CP018419.1\|WP_004524980.1\|1194912_1196316_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NZ_CP018419.1\|WP_004188840.1\|1196326_1198120_-\|polyhydroxyalkanoic-acid-synthase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NZ_CP018419.1\|WP_085561159.1\|1198480_1200127_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NZ_CP018419.1\|WP_071811430.1\|1210773_1212609_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	5.65725e-132
NZ_CP018419.1\|WP_004529184.1\|1193737_1194916_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NZ_CP018419.1\|WP_009969306.1\|1217112_1218186_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	2.70657e-39
NZ_CP018419.1\|WP_058040623.1\|1203050_1205057_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NZ_CP018419.1\|WP_004524985.1\|1201052_1201361_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	4.12229e-10
NZ_CP018419.1\|WP_004533337.1\|1205053_1205902_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	4.46992e-34

>NZ_CP018419.1|WP_004187193.1|1202055_1202304_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NZ_CP018419.1|WP_004187346.1|1201357_1202059_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NZ_CP018419.1|WP_004524985.1|1201052_1201361_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFVAGACHFVSLGWNSRLFVAGRAGVALALQLARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NZ_CP018419.1|WP_085503029.1|1200568_1201060_+|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRDAARRDPSPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NZ_CP018419.1|WP_009982027.1|1200116_1200572_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIAAPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NZ_CP018419.1|WP_085561159.1|1198480_1200127_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAACAERDASDVGDARDEGAGRVVAVRGAVIDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPPLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSGTTSGTTSGTTSGTTSGTTSDPASGSAEPQGARHGR
>NZ_CP018419.1|WP_004188840.1|1196326_1198120_-|polyhydroxyalkanoic-acid-synthase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NZ_CP018419.1|WP_004524980.1|1194912_1196316_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGARLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NZ_CP018419.1|WP_004529184.1|1193737_1194916_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHLRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NZ_CP018419.1|WP_172411934.1|1191721_1193008_+|hexose-kinase
MRGACASRAMFDTGGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASSKQQAASSKQQAASSSRSSPGLMVRRRIERKHCGACPPRSTREPRTRASRCVVFPSRIPTLKPNVTMPEIVTLTPNPAIDVATCVERVTDTRKLRCGPARRDPGGGGINVARVLTRLGADCSAVYLAGGGTGLALRGLLADEGVRAHGIDIAGETRENFSVLETSTGREFRFVLPGPALAAHEWPRCVEALGRLADASRYLVMSGSLPPGMPDDCYARLARRASARGVRTVVDTSGPALAAALDAGVYLVKPSLGELRALTGLPLEDDGARLAAARAIVAGGRVQIVALTLGDAGALVVSRDDAVRLPGVKVAVRSAIGAGDSFVAGLVAALNRGANVADAARHALAAASASLLSTGTALGTKEDIARIYRELPGTIDA
>NZ_CP018419.1|WP_058040623.1|1203050_1205057_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAAAADAATGAGWLARRRGALARVALAPVAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGALDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSPEASREVSREVSREVSHEANRDAAADAARVAGRAPGRAEPDRAAPRAMPDGPPRAQADGDRASASRPRPDARGDAARTAPSPQGGADANVNADANVDAEAEARHKR
>NZ_CP018419.1|WP_004533337.1|1205053_1205902_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGDTAAGARAAPRARLVVVLCSEQGFVGAYNAQLIEHATRPEPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NZ_CP018419.1|WP_085561161.1|1206120_1207146_+|alcohol-dehydrogenase-AdhP
MAQYMQAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGAAFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NZ_CP018419.1|WP_045597583.1|1207205_1207709_+|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDMHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGRAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NZ_CP018419.1|WP_009969313.1|1207766_1208276_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAAGGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVGTMIGVSVPNTRLKHFEDAVDNGELLTMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NZ_CP018419.1|WP_004524990.1|1208816_1210382_+|methyl-accepting-chemotaxis-protein
MPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NZ_CP018419.1|WP_071811430.1|1210773_1212609_-|response-regulator
MHVEVFAQHSSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLDAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRARGARHAQADPRAKTAAARVQR
>NZ_CP018419.1|WP_004552097.1|1212758_1213883_-|ABC-transporter-permease
MRRLAIVYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMNAGDFTFVLDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRKFLILAVIGTALFLLSLKRFRKTIGQMA
>NZ_CP018419.1|WP_085561162.1|1213885_1217116_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQGGAGERAAGESLAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVGSDVGSDVASEAGPEAGLAASAESGAERAREPAADITADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPPSHAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHDLYSQFWPLAASVPVILGATILLLKKQER
>NZ_CP018419.1|WP_009969306.1|1217112_1218186_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MIQVTRKQIVAAAAVVVVALGAYYGWTLLRHQGPGDGFASGNGRIEATEIDVATKLPGRIDAILVDEGDFVKAGQPLANMQIQVLRAQYDEATAQRQRALNTAAGVQSQVAQRKSDKAAAQAMVVLRESELDAAERRLARSQTLSREGASSLQELDDDRARARSAQAAVSAAAAQVAAAQAAIEATEAQLVAAHSAVTAADATVARVQADIDDSQLASPRDGRVQYRVAQPGEVLPAGGKVLNLVDLSDVYMTFFLPETVVGRVALGADARIILDAAPNYVIPATVSFVSSTAQFTPKTVETANERQKLMFRVKARIDRELLQKHLKLVKTGLPGVAWVRVDPSKPWPAQLMVKVAQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP018419_1	1.4\|607142\|24\|NZ_CP018419\|CRT	607142-607165	24	NZ_CP018419.1	606806-606829	1	0.958
NZ_CP018419_1	1.11\|607436\|24\|NZ_CP018419\|CRT	607436-607459	24	NZ_CP018419.1	606806-606829	1	0.958
NZ_CP018419_1	1.21\|607856\|24\|NZ_CP018419\|CRT	607856-607879	24	NZ_CP018419.1	606974-606997	1	0.958
NZ_CP018419_1	1.22\|607898\|24\|NZ_CP018419\|CRT	607898-607921	24	NZ_CP018419.1	606806-606829	1	0.958
NZ_CP018419_1	1.24\|607982\|24\|NZ_CP018419\|CRT	607982-608005	24	NZ_CP018419.1	606890-606913	1	0.958
NZ_CP018419_1	1.26\|608066\|24\|NZ_CP018419\|CRT	608066-608089	24	NZ_CP018419.1	606890-606913	1	0.958
NZ_CP018419_1	1.9\|607352\|24\|NZ_CP018419\|CRT	607352-607375	24	NZ_CP018419.1	606806-606829	2	0.917
NZ_CP018419_1	1.13\|607520\|24\|NZ_CP018419\|CRT	607520-607543	24	NZ_CP018419.1	606806-606829	2	0.917
NZ_CP018419_1	1.15\|607604\|24\|NZ_CP018419\|CRT	607604-607627	24	NZ_CP018419.1	606806-606829	2	0.917
NZ_CP018419_1	1.21\|607856\|24\|NZ_CP018419\|CRT	607856-607879	24	NZ_CP018419.1	606890-606913	2	0.917
NZ_CP018419_1	1.24\|607982\|24\|NZ_CP018419\|CRT	607982-608005	24	NZ_CP018419.1	606974-606997	2	0.917
NZ_CP018419_1	1.26\|608066\|24\|NZ_CP018419\|CRT	608066-608089	24	NZ_CP018419.1	606974-606997	2	0.917
NZ_CP018419_1	1.28\|608150\|24\|NZ_CP018419\|CRT	608150-608173	24	NZ_CP018419.1	606806-606829	2	0.917

1. spacer 1.4|607142|24|NZ_CP018419|CRT matches to position: 606806-606829, mismatch: 1, identity: 0.958

ctgcccgtcgcttgcgagccttgg	CRISPR spacer
ctgcccgccgcttgcgagccttgg	Protospacer
*******.****************

2. spacer 1.11|607436|24|NZ_CP018419|CRT matches to position: 606806-606829, mismatch: 1, identity: 0.958

ctgcccgtcgcttgcgagccttgg	CRISPR spacer
ctgcccgccgcttgcgagccttgg	Protospacer
*******.****************

3. spacer 1.21|607856|24|NZ_CP018419|CRT matches to position: 606974-606997, mismatch: 1, identity: 0.958

tcccccgtcgcttgcgagccttgg	CRISPR spacer
tcccctgtcgcttgcgagccttgg	Protospacer
*****.******************

4. spacer 1.22|607898|24|NZ_CP018419|CRT matches to position: 606806-606829, mismatch: 1, identity: 0.958

ctgcccgtcgcttgcgagccttgg	CRISPR spacer
ctgcccgccgcttgcgagccttgg	Protospacer
*******.****************

5. spacer 1.24|607982|24|NZ_CP018419|CRT matches to position: 606890-606913, mismatch: 1, identity: 0.958

tcccccgtcgcttgcgaaccttgg	CRISPR spacer
tcccccgtcgcttgcgcaccttgg	Protospacer
**************** *******

6. spacer 1.26|608066|24|NZ_CP018419|CRT matches to position: 606890-606913, mismatch: 1, identity: 0.958

tcccccgtcgcttgcgaaccttgg	CRISPR spacer
tcccccgtcgcttgcgcaccttgg	Protospacer
**************** *******

7. spacer 1.9|607352|24|NZ_CP018419|CRT matches to position: 606806-606829, mismatch: 2, identity: 0.917

ctgcccgtcgcttgcgaaccttgg	CRISPR spacer
ctgcccgccgcttgcgagccttgg	Protospacer
*******.*********.******

8. spacer 1.13|607520|24|NZ_CP018419|CRT matches to position: 606806-606829, mismatch: 2, identity: 0.917

ctgcccgtcgcttgcgaaccttgg	CRISPR spacer
ctgcccgccgcttgcgagccttgg	Protospacer
*******.*********.******

9. spacer 1.15|607604|24|NZ_CP018419|CRT matches to position: 606806-606829, mismatch: 2, identity: 0.917

ctgcccgtcgcttgcgaaccttgg	CRISPR spacer
ctgcccgccgcttgcgagccttgg	Protospacer
*******.*********.******

10. spacer 1.21|607856|24|NZ_CP018419|CRT matches to position: 606890-606913, mismatch: 2, identity: 0.917

tcccccgtcgcttgcgagccttgg	CRISPR spacer
tcccccgtcgcttgcgcaccttgg	Protospacer
**************** .******

11. spacer 1.24|607982|24|NZ_CP018419|CRT matches to position: 606974-606997, mismatch: 2, identity: 0.917

tcccccgtcgcttgcgaaccttgg	CRISPR spacer
tcccctgtcgcttgcgagccttgg	Protospacer
*****.***********.******

12. spacer 1.26|608066|24|NZ_CP018419|CRT matches to position: 606974-606997, mismatch: 2, identity: 0.917

tcccccgtcgcttgcgaaccttgg	CRISPR spacer
tcccctgtcgcttgcgagccttgg	Protospacer
*****.***********.******

13. spacer 1.28|608150|24|NZ_CP018419|CRT matches to position: 606806-606829, mismatch: 2, identity: 0.917

ctgcccgtcgcttgcgaaccttgg	CRISPR spacer
ctgcccgccgcttgcgagccttgg	Protospacer
*******.*********.******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018419_1	1.31\|608276\|24\|NZ_CP018419\|CRT	608276-608299	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3366341-3366364	2	0.917
NZ_CP018419_1	1.31\|608276\|24\|NZ_CP018419\|CRT	608276-608299	24	NZ_CP054618	Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence	194448-194471	3	0.875
NZ_CP018419_1	1.31\|608276\|24\|NZ_CP018419\|CRT	608276-608299	24	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	169321-169344	3	0.875
NZ_CP018419_1	1.5\|607184\|24\|NZ_CP018419\|CRT	607184-607207	24	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	15063-15086	4	0.833
NZ_CP018419_1	1.5\|607184\|24\|NZ_CP018419\|CRT	607184-607207	24	NZ_CP035902	Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence	58203-58226	4	0.833
NZ_CP018419_1	1.10\|607394\|24\|NZ_CP018419\|CRT	607394-607417	24	NZ_CP024936	Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence	362719-362742	4	0.833
NZ_CP018419_1	1.12\|607478\|24\|NZ_CP018419\|CRT	607478-607501	24	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	15063-15086	4	0.833
NZ_CP018419_1	1.12\|607478\|24\|NZ_CP018419\|CRT	607478-607501	24	NZ_CP035902	Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence	58203-58226	4	0.833
NZ_CP018419_1	1.14\|607562\|24\|NZ_CP018419\|CRT	607562-607585	24	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	15063-15086	4	0.833
NZ_CP018419_1	1.14\|607562\|24\|NZ_CP018419\|CRT	607562-607585	24	NZ_CP035902	Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence	58203-58226	4	0.833
NZ_CP018419_1	1.16\|607646\|24\|NZ_CP018419\|CRT	607646-607669	24	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	15063-15086	4	0.833
NZ_CP018419_1	1.16\|607646\|24\|NZ_CP018419\|CRT	607646-607669	24	NZ_CP035902	Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence	58203-58226	4	0.833
NZ_CP018419_1	1.17\|607688\|24\|NZ_CP018419\|CRT	607688-607711	24	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	210775-210798	4	0.833
NZ_CP018419_1	1.19\|607772\|24\|NZ_CP018419\|CRT	607772-607795	24	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	210775-210798	4	0.833
NZ_CP018419_1	1.23\|607940\|24\|NZ_CP018419\|CRT	607940-607963	24	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	15063-15086	4	0.833
NZ_CP018419_1	1.23\|607940\|24\|NZ_CP018419\|CRT	607940-607963	24	NZ_CP035902	Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence	58203-58226	4	0.833
NZ_CP018419_1	1.24\|607982\|24\|NZ_CP018419\|CRT	607982-608005	24	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	210775-210798	4	0.833
NZ_CP018419_1	1.25\|608024\|24\|NZ_CP018419\|CRT	608024-608047	24	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	15063-15086	4	0.833
NZ_CP018419_1	1.25\|608024\|24\|NZ_CP018419\|CRT	608024-608047	24	NZ_CP035902	Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence	58203-58226	4	0.833
NZ_CP018419_1	1.26\|608066\|24\|NZ_CP018419\|CRT	608066-608089	24	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	210775-210798	4	0.833
NZ_CP018419_1	1.27\|608108\|24\|NZ_CP018419\|CRT	608108-608131	24	NC_012725	Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence	15063-15086	4	0.833
NZ_CP018419_1	1.27\|608108\|24\|NZ_CP018419\|CRT	608108-608131	24	NZ_CP035902	Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence	58203-58226	4	0.833
NZ_CP018419_1	1.6\|607226\|24\|NZ_CP018419\|CRT	607226-607249	24	NZ_CP024936	Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence	362719-362742	5	0.792
NZ_CP018419_1	1.18\|607730\|24\|NZ_CP018419\|CRT	607730-607753	24	NZ_CP024936	Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence	362719-362742	5	0.792
NZ_CP018419_1	1.20\|607814\|24\|NZ_CP018419\|CRT	607814-607837	24	NZ_CP024936	Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence	362719-362742	5	0.792
NZ_CP018419_1	1.31\|608276\|24\|NZ_CP018419\|CRT	608276-608299	24	NZ_CP016453	Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence	640343-640366	5	0.792

1. spacer 1.31|608276|24|NZ_CP018419|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 2, identity: 0.917

ctgcccgtcgcctgcgcaccgtta	CRISPR spacer
ctgcccgtcgccggcgcaccgttc	Protospacer
************ **********

2. spacer 1.31|608276|24|NZ_CP018419|CRT matches to NZ_CP054618 (Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence) position: , mismatch: 3, identity: 0.875

ctgcccgtcgcctgcgcaccgtta	CRISPR spacer
ctggccgtcgcctgcgcgccgttc	Protospacer
*** *************.*****

3. spacer 1.31|608276|24|NZ_CP018419|CRT matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.875

ctgcccgtcgcctgcgcaccgtta	CRISPR spacer
ctgcccgtcgtctgcgtaccgttg	Protospacer
**********.*****.******.

4. spacer 1.5|607184|24|NZ_CP018419|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

5. spacer 1.5|607184|24|NZ_CP018419|CRT matches to NZ_CP035902 (Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

6. spacer 1.10|607394|24|NZ_CP018419|CRT matches to NZ_CP024936 (Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence) position: , mismatch: 4, identity: 0.833

gtgcccgacgcggtggcatcctgg	CRISPR spacer
ttgcccgacgcggtggcatcggtg	Protospacer
 *******************   *

7. spacer 1.12|607478|24|NZ_CP018419|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

8. spacer 1.12|607478|24|NZ_CP018419|CRT matches to NZ_CP035902 (Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

9. spacer 1.14|607562|24|NZ_CP018419|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

10. spacer 1.14|607562|24|NZ_CP018419|CRT matches to NZ_CP035902 (Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

11. spacer 1.16|607646|24|NZ_CP018419|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

12. spacer 1.16|607646|24|NZ_CP018419|CRT matches to NZ_CP035902 (Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

13. spacer 1.17|607688|24|NZ_CP018419|CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 4, identity: 0.833

ttccccgtcgcttgcgaaccttgg	CRISPR spacer
ggccccgacgcttgcgaaccttgc	Protospacer
  ***** ***************

14. spacer 1.19|607772|24|NZ_CP018419|CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 4, identity: 0.833

ttccccgtcgcttgcgaaccttgg	CRISPR spacer
ggccccgacgcttgcgaaccttgc	Protospacer
  ***** ***************

15. spacer 1.23|607940|24|NZ_CP018419|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtagcaccctgg	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
**************.******

16. spacer 1.23|607940|24|NZ_CP018419|CRT matches to NZ_CP035902 (Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtagcaccctgg	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
**************.******

17. spacer 1.24|607982|24|NZ_CP018419|CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 4, identity: 0.833

tcccccgtcgcttgcgaaccttgg	CRISPR spacer
ggccccgacgcttgcgaaccttgc	Protospacer
  ***** ***************

18. spacer 1.25|608024|24|NZ_CP018419|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtagcaccctgg	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
**************.******

19. spacer 1.25|608024|24|NZ_CP018419|CRT matches to NZ_CP035902 (Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtagcaccctgg	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
**************.******

20. spacer 1.26|608066|24|NZ_CP018419|CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 4, identity: 0.833

tcccccgtcgcttgcgaaccttgg	CRISPR spacer
ggccccgacgcttgcgaaccttgc	Protospacer
  ***** ***************

21. spacer 1.27|608108|24|NZ_CP018419|CRT matches to NC_012725 (Burkholderia glumae BGR1 plasmid bglu_4p, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

22. spacer 1.27|608108|24|NZ_CP018419|CRT matches to NZ_CP035902 (Burkholderia glumae strain 257sh-1 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.833

tcacccgacgcggtggcatcctgc	CRISPR spacer
tcacccgacgcggtggcacccgtt	Protospacer
******************.**  .

23. spacer 1.6|607226|24|NZ_CP018419|CRT matches to NZ_CP024936 (Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence) position: , mismatch: 5, identity: 0.792

gtgcccgacgcggtggcatcctga	CRISPR spacer
ttgcccgacgcggtggcatcggtg	Protospacer
 *******************   .

24. spacer 1.18|607730|24|NZ_CP018419|CRT matches to NZ_CP024936 (Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence) position: , mismatch: 5, identity: 0.792

gtgcccgacgcggtggcatcctga	CRISPR spacer
ttgcccgacgcggtggcatcggtg	Protospacer
 *******************   .

25. spacer 1.20|607814|24|NZ_CP018419|CRT matches to NZ_CP024936 (Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence) position: , mismatch: 5, identity: 0.792

gtgcccgacgcggtggcatcctga	CRISPR spacer
ttgcccgacgcggtggcatcggtg	Protospacer
 *******************   .

26. spacer 1.31|608276|24|NZ_CP018419|CRT matches to NZ_CP016453 (Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence) position: , mismatch: 5, identity: 0.792

ctgcccgtcgcctgcgcaccgtta	CRISPR spacer
tggcccgtcgcctgcgcaccggct	Protospacer
. ******************* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1023135 : 1057358

Acanthocystis_turfacea_Chlorella_virus(16.67%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190585.1\|1023135_1024539_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004529328.1\|1024554_1025871_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004524806.1\|1025873_1029503_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_122985123.1\|1029484_1030441_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004529325.1\|1030425_1030653_-	hypothetical protein	NA	NA	NA	NA
WP_076851822.1\|1030651_1033240_+	serine/threonine protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	5.0e-09	26.6
WP_009982092.1\|1033292_1034372_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004524810.1\|1034434_1035013_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190849.1\|1035005_1036514_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190698.1\|1036573_1037065_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_009935240.1\|1037083_1037632_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004524812.1\|1037636_1039508_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_028358324.1\|1039504_1040950_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_085561144.1\|1040962_1043629_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	5.2e-78	30.6
WP_085508262.1\|1043625_1045830_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.3e-45	29.9
WP_004524859.1\|1047741_1049010_+	hypothetical protein	NA	NA	NA	NA
WP_028200696.1\|1048996_1053655_+	type IV secretion protein Rhs	A0A2H4JFP5	uncultured_Caudovirales_phage	8.3e-23	34.9
WP_004533385.1\|1054247_1054511_+	putative Immunity protein 75	NA	NA	NA	NA
WP_076849157.1\|1054511_1054709_+	hypothetical protein	NA	NA	NA	NA
WP_004525642.1\|1054803_1056024_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	2.7e-239	99.8
WP_164978234.1\|1056160_1057358_+\|transposase	IS3-like element ISButh1 family transposase	A0A1B0Z042	Pseudomonas_phage	3.0e-102	65.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018418

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP018419

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection