CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020895	Legionella longbeachae strain F1157CHC plasmid pLLO-F1157CHC, complete sequence	1 crisprs	RT,PD-DExK,DEDDh	0	1	1	0
NZ_CP020894	Legionella longbeachae strain F1157CHC chromosome, complete genome	2 crisprs	DEDDh,cas3,WYL,DinG,csa3,RT	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020895_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020895_1

14195-14281

Orphan

Consensus_repeat	Method
TTGAATTGTGCCGACATTGTCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020895_1

>merge|NZ_CP020895|1|14195-14281|CRISPRCasFinder
TTGAATTGTGCCGACATTGTCGGCACTTTTTCTTCGGTAGGAGTAAAATATGGTAGCTCTTCGTTGAATTGTGCCGACACTGTCGGC

>NZ_CP020895|1|1|14195-14281|CRISPRCasFinder
TTGAATTGTGCCGACATTGTCGGC	ACTTTTTCTTCGGTAGGAGTAAAATATGGTAGCTCTTCG
TTGAATTGTGCCGACACTGTCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020895.2\|WP_105223267.1\|25343_26045_+\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP020895.2\|WP_085663054.1\|20254_20533_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020895.2\|WP_085662914.1\|22215_22644_+\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NZ_CP020895.2\|WP_125466282.1\|9827_10046_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020895.2\|WP_105223262.1\|10446_11484_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270783
NZ_CP020895.2\|WP_085663055.1\|21766_22024_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020895.2\|WP_085663056.1\|22842_23025_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369847
NZ_CP020895.2\|WP_105223263.1\|11623_12301_+\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP020895.2\|WP_003636923.1\|8287_9181_+\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NZ_CP020895.2\|WP_012979194.1\|6913_7288_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020895.2\|WP_085662914.1\|15966_16395_+\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NZ_CP020895.2\|WP_085663049.1\|13063_13366_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225495
NZ_CP020895.2\|WP_085663053.1\|16544_20165_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020895.2\|WP_105223266.1\|20704_21418_+\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP020895.2\|WP_085663128.1\|12705_13071_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368831
NZ_CP020895.2\|WP_085663057.1\|23841_24846_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020895.2\|WP_085663042.1\|2260_3268_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020895.2\|WP_085663058.1\|26434_26758_-\|DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225495
NZ_CP020895.2\|WP_105223258.1\|7247_8147_-\|reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|238828
NZ_CP020895.2\|WP_105223261.1\|9213_9849_-\|transposase	unknown	unknown	gnl\|CDD\|376773

Protein	Function_ID	Function_description	E-value
NZ_CP020895.2\|WP_105223267.1\|25343_26045_+\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.60377e-63
NZ_CP020895.2\|WP_085663058.1\|26434_26758_-\|DNA-binding-transcriptional-regulator	gnl\|CDD\|225495	COG2944, COG2944, Predicted transcriptional regulator [Transcription].	3.15575e-43
NZ_CP020895.2\|WP_105223262.1\|10446_11484_+\|hypothetical-protein	gnl\|CDD\|270783	cd06606, STKc_MAPKKK, Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. MAPKKKs (MKKKs or MAP3Ks) are also called MAP/ERK kinase kinases (MEKKs) in some cases. They phosphorylate and activate MAPK kinases (MAPKKs or MKKs or MAP2Ks), which in turn phosphorylate and activate MAPKs during signaling cascades that are important in mediating cellular responses to extracellular signals. This subfamily is composed of the Apoptosis Signal-regulating Kinases ASK1 (or MAPKKK5) and ASK2 (or MAPKKK6), MEKK1, MEKK2, MEKK3, MEKK4, as well as plant and fungal MAPKKKs. Also included in this subfamily are the cell division control proteins Schizosaccharomyces pombe Cdc7 and Saccharomyces cerevisiae Cdc15. The MAPKKK subfamily is part of a larger superfamily that includes the catalytic domains of other STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.68015e-09
NZ_CP020895.2\|WP_105223263.1\|11623_12301_+\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.71422e-66
NZ_CP020895.2\|WP_003636923.1\|8287_9181_+\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	8.10773e-24
NZ_CP020895.2\|WP_085663056.1\|22842_23025_-\|hypothetical-protein	gnl\|CDD\|369847	pfam08388, GIIM, Group II intron, maturase-specific domain. This region is found mainly in various bacterial and archaeal species, but a few members of this family are expressed by fungal and chlamydomonal species. It has been implicated in the binding of intron RNA during reverse transcription and splicing.	5.93816e-13
NZ_CP020895.2\|WP_105223266.1\|20704_21418_+\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.91298e-66
NZ_CP020895.2\|WP_085663049.1\|13063_13366_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225495	COG2944, COG2944, Predicted transcriptional regulator [Transcription].	7.07179e-14
NZ_CP020895.2\|WP_085662914.1\|15966_16395_+\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	7.35268e-38
NZ_CP020895.2\|WP_085663128.1\|12705_13071_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368831	pfam06296, RelE, RelE toxin of RelE / RelB toxin-antitoxin system. RelE is a family of Gram-negative bacterial antitoxins of the RelE/RelB toxin-antitoxin system. Its cognate antitoxin is family RelB, pfam04221.	0.00486898
NZ_CP020895.2\|WP_105223261.1\|9213_9849_-\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	7.82088e-19
NZ_CP020895.2\|WP_105223258.1\|7247_8147_-\|reverse-transcriptase	gnl\|CDD\|238828	cd01651, RT_G2_intron, RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).	2.75416e-26
NZ_CP020895.2\|WP_085662914.1\|22215_22644_+\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	7.35268e-38

>NZ_CP020895.2|WP_085663049.1|13063_13366_+|helix-turn-helix-domain-containing-protein
MSEIGKSLIQGVEEALEYAKGQTKGTITHKVKVPLEIDVTAIRKKLHMSRKKFSDEFGFSIRTLEKWERGERLPEGPARAYLTVIEKNPAAVIDALHQAS
>NZ_CP020895.2|WP_085663128.1|12705_13071_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKIKTILQTVVEMPEFIRQSDSCMDEESKRSFISYIAEHPLDGDLIVGTGGVRKIRWTGDSNKGKRGGVRVIYYYYDQSIPIFLLTVYRKNQKDNLTQEEKHIVKSIIGKIVDAYKENGHE
>NZ_CP020895.2|WP_105223263.1|11623_12301_+|IS6-family-transposase
MISFKWKHFKRDIILMLVRWYLAYSLSYRDIEELALERGLKVDHSTINRWVIEYSPQLEEAFRGRHKRATVSSLRMDETYIKVKGQWMYLYRAVDKEGNTVDFMLSEKRDEPAACVLFIKVIGSNGVPEKVAMVKSGANKAGIGTINRTLALLFMMGGVFLQIDVRQIKYLNNIVEQDHRFIKKITKPMKGFKAFHSAESTLAGIELHHMLRKGQHLQAGSQFYL
>NZ_CP020895.2|WP_105223262.1|10446_11484_+|hypothetical-protein
MPRTINLSKPRTLTLEELDIIGLLFETYPDKKSFSEGYYQLQFQGSPLEISLKDGTAIRVSRRDPQKGDRCYFCTKDTIGEGGVGTAHEAVKLKFFKDCHSKQSTISPRLYAVKKSNSSSLEDEAEFAAKLDYMHAKPLMVDEKTYYLVMEKFNVKPIMTLEEHLDFSLSFLQCLKNLHEHGIIHCDLQTGNRLHMGNILFDGKRVCLIDFNNSRELYVDDESGGINIYLMQRDLYDWKRSVEGITKQFNGKDRADVVQTFEEFFIRPHIARLMTDDTQKMWRQKKFKESFSNFGKKEEYYQLFNQAVNDFSGLIQDLKTEHQQRILSERIAEDNNLGRLYIANS
>NZ_CP020895.2|WP_125466282.1|9827_10046_-|hypothetical-protein
MDKKIVAVDIAKSELVIYLNGSYSIIANESTVIRTFLTQYTNKRIELFAFEATGVMKKDWLIVLKTCLYPTA
>NZ_CP020895.2|WP_105223261.1|9213_9849_-|transposase
MSLPYRMMHANHIRAYAKALGVLAKTDKLDAKVLHDYAVTVSLEAASSRNDNQEISDLLNRREQLIDMRIEESNRLETMTNKALIKSFKAHIRWIEKQVEKIESQLSDYINSNNSVKSLFELYSSVPGVGLITAMRLIADLPELLSHTDKQLAALIGVAPMNNDSGKMRGNRSIIGGRAKIRRVLYLATIAAIKFNPLIKSGSVAKTNDSL
>NZ_CP020895.2|WP_003636923.1|8287_9181_+|IS982-family-transposase
MSVEEFIIAVYCLVDDIMNELLNSKSLRQRGFNPALTDSEMIAMELVAEFQGIDTDKGAWEYFCNHWRALFPNIGSRANFAKHAANLWNMKQQIQKVLAGRMGAFTDLLHISDGFPVPVCHFRRANFSQVFAGEATYGYCASKGETYYGFKGNVLINSDGIITGITLSQAHIDERESLWDLVDGIHGMIIADKGLIGSEYQNELREYSGIDLQTAVRSNMEDKRGKHFSKWLTSTRRLVETVIGQLTERFQIEKVRARKLWYLTNRVARKVLAHTVCAYINKKMGNPPLQFELLVKS
>NZ_CP020895.2|WP_105223258.1|7247_8147_-|reverse-transcriptase
MFQAGQKLFERIRRKKRMASANHDVHLLARTINEWLPQGIQSLIEGTYTPRFLKRYYFKDEMLDQLYLADRVLQNLLLQQLKPTFPYVMNPNCYHVHGPSGVQLAAQRIRETLATKHYKYIIRADIKSYYKSIQHHVLIEDIKRYYFDTKVQLMLEQIVRNPIETPRGYKNPDNGIALRGPLSQFFSALYLKPLDDAFDTLDVTYLRYQDDIIILCHSKRQLERCKRRLMTILKERHLQLSRKKTRIGAIEGGFHFLGINYLEPQSPGSTNVTQDIREMAVNAPLTDDSCLLFNQTGGG
>NZ_CP020895.2|WP_012979194.1|6913_7288_-|hypothetical-protein
MILVCYLTKLGGGNNNSIKPNQEYPEPITIVPHPRTIRKAREQVRLMVIDGFSIPRIRSYLTAWSRWWVRTSQVWSHQTLLIQFIRSCYDPQIAGIGAEILLINLRRMDQPAGMMAQPDWQESV
>NZ_CP020895.2|WP_085663042.1|2260_3268_-|hypothetical-protein
MEVNSDFEIFIGVVAPLGTERKWFIDVLEEKFESRGYIIEKISITNEIIQFTKNDCKALSFEYFVKMEACNQLRKEYSNGFLMGVIIDKIRSLRKSGNKKVVYIIEQIKNVTEYNILSHIYGLNYLQISLFSNEKSRDENLRAKFKNDCVNNLINYEFKPNKINFLKERMNENVSILFQNISKAIRSKFKEEILPDVTHNLIKKDFNEIVNDTKSHGQQVSELFHLSHYFFNLDASKIKITKELNKFISLIEGDNEDYPTQDEFGMSLAFQVSVRSNFPNNRHIGASILSPYGEVISVASIRAPCSSSNTTLFDQYQVQEGYKKYKNQIKGLRCK
>NZ_CP020895.2|WP_085662914.1|15966_16395_+|IS200/IS605-family-transposase
MTLKRASHCVYQTHYHIVFPVKYRKSLLSDEITSAIKSIAGEIGERYEIDFEQLGCDKNHIHILCSFHPKYSISEVVRKFKSITARELFKQFPLLKKDLWGGEFWSDGYYVSTVGERGDWRVVERYVKNQGKESETKQLRLI
>NZ_CP020895.2|WP_085663053.1|16544_20165_-|hypothetical-protein
MTDYIDIYNKLKQKRSRYGAVLGTLDKIGENLKQTSESWNPINLFFYSKKAKGQHELILNLQAELRKMLITLRETPEMRQNMRTIINKYRDRVQDKDARAFIKSIDEEIEQVDFNTRPFKDAYLLQNQDAKQKVEQHIISNIKPLAEHVRWAFNHIYNVPYPGHLPKEGVARVIHGIEHVTRAATYIPVLANLYRQYKDKEALALTEDDLKLLQIAAVFHDAARQGDEEDLWDNQSALLCYSYLTSVLKVSHEKAKMMAETIANKDVRKDVFLELIHDVQGTLTFVKGAPRAKNIYQKLLHDADCIDIIRARDHFDAGHLDFYKEIASKTHSAFESMAKLIVEIRGLIIKTGDERGHLDYTKKKLYENENAFAALESVIQNSSDQFELLPTLYHGNRLLSSVELQKIKRDVPYDKKADITSANLEAAAREGKLFARGILAPTGIIKKSSKADENATQIELRKTARRNGVPTRSTKLGFAPKDKEGNPNRSISMLGYGASTFSAAGFLILDPAMKQIQGIYEQDSDTGWGKKKVGLHDVQNISNVAALSDEDKASQIKMLNERLKMGGVKPRFYKNDALGHSELVCHITKFDAIYFSNDRCLGNALLKSGLEPNHKYAPLLQALFLQKECERRYHKTLPIIDYSSTRNKMTVLASPSEEQITSMWVEMVSNYITNQLKLEDNTIFSMSENDLKVRALYGSLAIKSKKVDWDHLASADSNYPGELQQKISGRIREVYQQKTAAYYNEVETQLKEGLSIDKKALHALNHSPELLNRLKELIRPQLDKYIQSKGELRTVDKEFKEAYSLVKAIQDKDLEDLLLNKVSKYVQEKLSFVKENRANLIEDPNELVYLLKEIKALSQEFHFSEYEKMLDTEIDAIIKYYAAPKKQEYIELDKISVNPKPIGLTAGEVRAIQKPFNMTMDETDTLPNFAAFIRGMPVNLSVENKLLVEEWCTNYCIKGERIEKQINNYLLLAKTADVSFEKQKSKLLEVFNREPELGASDLTEALGKSTFLLKDNAIFSKIEQYCSKRSSLFNYSFDVIEIVDAIGEPNAVQIELIVKRLHTYMDKERAETLPLKDPISCCRMLRNFLDIARISTETTSTLFRDAIWPTVVKTDLDKYMSACVNLNHEDFLSYLPEFIYAAKCAPFDMSPIVKHIQTNYTAEDLSPIFNKIKYEGDIKKMNIFRQLVPESHMKELLAVIDRTVTN
>NZ_CP020895.2|WP_085663054.1|20254_20533_-|hypothetical-protein
MTDSISTSDKPKTSAGIVIDCLDLLFVIMAISSKVFILAIVLKISLQREDAKSRIYGLLSKTPIVTTFHSGEKPIGRFGQFGALGIIPNTTT
>NZ_CP020895.2|WP_105223266.1|20704_21418_+|IS6-family-transposase
MRSTKPAAFKWRHFHGEVILQCVRWYCKYGISYRDLEEMMSERGLEIDHTTLYRWVQHYAPELKKRLDWHKKRYASRWHLDETYIKIKGEWKYLYRAIDERGNTIDFYLSHRRNAKAAKRFLKKLIKSNPTCDVSVINTDKNPAYGQAIKELKQEKSLASGVSHLQIKYRNNRLEADHGKLKRLINPVRGFQSMKTAYATIKGFEIMRMFKKGQFNIWMYGNRTEISFINEQFGLYS
>NZ_CP020895.2|WP_085663055.1|21766_22024_-|hypothetical-protein
MKVASCVLRGLILSNGEWLLDNINKSASNLAESTVESLINQRCKGQQHMRWSREGLDPLLQLRAAIGSNDWDKIWKTAVMNAISA
>NZ_CP020895.2|WP_085662914.1|22215_22644_+|IS200/IS605-family-transposase
MTLKRASHCVYQTHYHIVFPVKYRKSLLSDEITSAIKSIAGEIGERYEIDFEQLGCDKNHIHILCSFHPKYSISEVVRKFKSITARELFKQFPLLKKDLWGGEFWSDGYYVSTVGERGDWRVVERYVKNQGKESETKQLRLI
>NZ_CP020895.2|WP_085663056.1|22842_23025_-|hypothetical-protein
MRENPIPTELIIVQLNQKITGWTNYYRGAVSSRTFSKVDSEIFFALKRWCLQRHARKSKK
>NZ_CP020895.2|WP_085663057.1|23841_24846_-|hypothetical-protein
MKTKVSDCSWKRSRSQDLIDFDTSDLQATDEIAINGMLYTEEDFIVKPQANDCLKFKALKAGQLFWELSPRESGVIELKIQFIDKDNRKLLHFLSLDIAKSQVVEHFQPIKLLKEALDQLCLKNDAVQQRQNLQEIRAFLTKLMRHEPIREKEVTDFKKHYTSIFRQNSTKQKEPVLGNFDEVIKKLSADLQTKNLKKECKKIEEILNDFKENIKNIGVNYPIAKIVAMTLEDSMRKSYGEYKSASTACTSQKELALAKEKFQKSCKELIATARPTLERDLEWGDYLKNILKSIANTMAYGVTFCQFSSFFPIVKSKTSEYAAETERKLNVILQ
>NZ_CP020895.2|WP_105223267.1|25343_26045_+|IS6-family-transposase
MISFKWKHFKRDIILMLVRWYLAYSLSYRDIEELALERGLKVDHSTINRSPMEDSPQLEEAFRRRHKRATVSSLRMDETYIKVKGQWMYLYPAVDKEGNTVDFMLPEKRDEPAARAFFIKVIGSNGVPEKVTMAKSGANKAGIDTIHRTLALLFMMGGVFLQIDVRQIKYLNNIVEQDHRFIKKITKPMKGFKAFHSAESTLAGIELHHMLRKGQHLQAGNQSIFEQFYGLAA
>NZ_CP020895.2|WP_085663058.1|26434_26758_-|DNA-binding-transcriptional-regulator
MKTKRKYKSEALEAIHSSANALLEIGAIDKATMRDFDDACFIEVPEIEATQIKAIREKNHVSQPVFARYLNTSKSTVQKWEIGAKKPSGMALKLLSVVQKHGLHILD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020895_1	1.1\|14219\|39\|NZ_CP020895\|CRISPRCasFinder	14219-14257	39	NZ_CP020895	Legionella longbeachae strain F1157CHC plasmid pLLO-F1157CHC, complete sequence	14219-14257	0	1.0

1. spacer 1.1|14219|39|NZ_CP020895|CRISPRCasFinder matches to NZ_CP020895 (Legionella longbeachae strain F1157CHC plasmid pLLO-F1157CHC, complete sequence) position: , mismatch: 0, identity: 1.0

actttttcttcggtaggagtaaaatatggtagctcttcg	CRISPR spacer
actttttcttcggtaggagtaaaatatggtagctcttcg	Protospacer
***************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

90 : 28294

Escherichia_phage(42.86%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172622932.1\|90_831_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_085663042.1\|2260_3268_-	hypothetical protein	NA	NA	NA	NA
WP_012979194.1\|6913_7288_-	hypothetical protein	NA	NA	NA	NA
WP_105223258.1\|7247_8147_-	reverse transcriptase	H7BVN7	unidentified_phage	1.5e-05	24.5
WP_003636923.1\|8287_9181_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_105223261.1\|9213_9849_-\|transposase	transposase	Q75QL1	Wolbachia_phage	2.1e-14	30.1
WP_125466282.1\|9827_10046_-	hypothetical protein	NA	NA	NA	NA
WP_105223262.1\|10446_11484_+	hypothetical protein	NA	NA	NA	NA
WP_105223263.1\|11623_12301_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	5.8e-42	43.6
WP_085663128.1\|12705_13071_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_085663049.1\|13063_13366_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_085663050.1\|13467_14589_-	DUF1016 family protein	Q9JMP5	Wolbachia_phage	1.6e-25	32.1
WP_085662914.1\|15966_16395_+\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_085663053.1\|16544_20165_-	hypothetical protein	NA	NA	NA	NA
WP_085663054.1\|20254_20533_-	hypothetical protein	NA	NA	NA	NA
WP_105223266.1\|20704_21418_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	8.1e-71	58.5
WP_085663055.1\|21766_22024_-	hypothetical protein	NA	NA	NA	NA
WP_085662914.1\|22215_22644_+\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_085663056.1\|22842_23025_-	hypothetical protein	NA	NA	NA	NA
WP_085663057.1\|23841_24846_-	hypothetical protein	NA	NA	NA	NA
WP_105223267.1\|25343_26045_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.5e-37	43.1
WP_085663058.1\|26434_26758_-	DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_085663059.1\|26741_27101_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_085663060.1\|27360_27513_-	PIN domain-containing protein	NA	NA	NA	NA
WP_085663061.1\|27586_28294_+\|transposase	IS6 family transposase	A0A1X9I6E7	Streptococcus_phage	3.9e-25	36.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP020894

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020894_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020894_1

1188664-1188755

Orphan

Consensus_repeat	Method
TATTAATGCTAAAAAAAAGACTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020894_1

>merge|NZ_CP020894|1|1188664-1188755|CRISPRCasFinder
TATTAATGCTAAAAAAAAGACTGAAATCCATAACGTATTCGGAAATAATGCCAGTAACCAATGTAAGGTTATTAATGCTAAAAAAAAGACTG

>NZ_CP020894|1|1|1188664-1188755|CRISPRCasFinder
TATTAATGCTAAAAAAAAGACTG	AAATCCATAACGTATTCGGAAATAATGCCAGTAACCAATGTAAGGT
TATTAATGCTAAAAAAAAGACTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020894.3\|WP_085662938.1\|1186426_1186651_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003632353.1\|1192017_1192449_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_085662939.1\|1190542_1191709_-\|GTPase	unknown	unknown	gnl\|CDD\|238090
NZ_CP020894.3\|WP_003632364.1\|1183113_1184136_+\|aminoglycoside-phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|366736
NZ_CP020894.3\|WP_003632349.1\|1200155_1200392_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003632366.1\|1181257_1182391_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP020894.3\|WP_085662941.1\|1197853_1199869_+\|GDSL-family-lipase	unknown	unknown	gnl\|CDD\|238882
NZ_CP020894.3\|WP_080619801.1\|1188107_1188341_+\|Tn3-family-transposase	unknown	unknown	gnl\|CDD\|376561
NZ_CP020894.3\|WP_012978947.1\|1179501_1180347_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP020894.3\|WP_003632345.1\|1204249_1204966_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|366166
NZ_CP020894.3\|WP_003632369.1\|1178213_1179509_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274922
NZ_CP020894.3\|WP_003632370.1\|1176575_1178213_+\|fatty-acyl-AMP-ligase	unknown	unknown	gnl\|CDD\|341254
NZ_CP020894.3\|WP_085662940.1\|1192646_1195802_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_085662937.1\|1166648_1176497_-\|hybrid-non-ribosomal-peptide-synthetase/type-I-polyketide-synthase	unknown	unknown	gnl\|CDD\|237108
NZ_CP020894.3\|WP_012978948.1\|1180330_1181257_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP020894.3\|WP_105166095.1\|1185465_1186038_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213218
NZ_CP020894.3\|WP_003632342.1\|1206214_1207441_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_012978952.1\|1196113_1197721_+\|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl\|CDD\|240528
NZ_CP020894.3\|WP_085662942.1\|1200834_1204236_+\|TM0106-family-RecB-like-putative-nuclease	unknown	unknown	gnl\|CDD\|274603
NZ_CP020894.3\|WP_003632344.1\|1204979_1205882_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|377216

Protein	Function_ID	Function_description	E-value
NZ_CP020894.3\|WP_085662941.1\|1197853_1199869_+\|GDSL-family-lipase	gnl\|CDD\|238882	cd01846, fatty_acyltransferase_like, Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Might catalyze fatty acid transfer between phosphatidylcholine and sterols.	1.62566e-39
NZ_CP020894.3\|WP_085662939.1\|1190542_1191709_-\|GTPase	gnl\|CDD\|238090	cd00159, RhoGAP, RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to GDP. The Rho family of small G proteins, which includes Cdc42Hs, activates effectors involved in a wide variety of developmental processes, including regulation of cytoskeleton formation, cell proliferation and the JNK signaling pathway. G proteins generally have a low intrinsic GTPase hydrolytic activity but there are family-specific groups of GAPs that enhance the rate of GTP hydrolysis by several orders of magnitude. The RhoGAPs are one of the major classes of regulators of Rho G proteins.	1.44228e-12
NZ_CP020894.3\|WP_003632364.1\|1183113_1184136_+\|aminoglycoside-phosphotransferase-family-protein	gnl\|CDD\|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	6.89234e-12
NZ_CP020894.3\|WP_003632366.1\|1181257_1182391_+\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	2.71161e-32
NZ_CP020894.3\|WP_080619801.1\|1188107_1188341_+\|Tn3-family-transposase	gnl\|CDD\|376561	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain. This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.	2.89105e-17
NZ_CP020894.3\|WP_012978947.1\|1179501_1180347_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	6.08452e-29
NZ_CP020894.3\|WP_003632345.1\|1204249_1204966_+\|alpha/beta-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.13016e-14
NZ_CP020894.3\|WP_003632369.1\|1178213_1179509_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274922	TIGR04020, non-ribosomal_peptide_synthetase, natural product biosynthesis luciferase-like monooxygenase domain. This model describes a subfamily within the bacterial luciferase-like monooxygenase (LLM) family that regularly occurs within large non-ribosomal protein synthases/polyketide synthases, but also as small proteins. The LLM family includes members that bind either FMN or F420, and FMN is more likely in this case because many members are from species that lack F420 biosynthesis capability. An example member is the MupA protein of mupirocin biosynthesis in Pseudomonas fluorescens NCIMB 10586.	3.37361e-170
NZ_CP020894.3\|WP_003632370.1\|1176575_1178213_+\|fatty-acyl-AMP-ligase	gnl\|CDD\|341254	cd05931, FAAL, Fatty acyl-AMP ligase (FAAL). FAAL belongs to the class I adenylate forming enzyme family and is homologous to fatty acyl-coenzyme A (CoA) ligases (FACLs). However, FAALs produce only the acyl adenylate and are unable to perform the thioester-forming reaction, while FACLs perform a two-step catalytic reaction; AMP ligation followed by CoA ligation using ATP and CoA as cofactors. FAALs have insertion motifs between the N-terminal and C-terminal subdomains that distinguish them from the FACLs. This insertion motif precludes the binding of CoA, thus preventing CoA ligation. It has been suggested that the acyl adenylates serve as substrates for multifunctional polyketide synthases to permit synthesis of complex lipids such as phthiocerol dimycocerosate, sulfolipids, mycolic acids, and mycobactin.	0
NZ_CP020894.3\|WP_085662937.1\|1166648_1176497_-\|hybrid-non-ribosomal-peptide-synthetase/type-I-polyketide-synthase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP020894.3\|WP_012978948.1\|1180330_1181257_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.98962e-89
NZ_CP020894.3\|WP_105166095.1\|1185465_1186038_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213218	cd03251, ABCC_MsbA, ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C. MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	4.25981e-89
NZ_CP020894.3\|WP_012978952.1\|1196113_1197721_+\|murein-biosynthesis-integral-membrane-protein-MurJ	gnl\|CDD\|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.29595e-144
NZ_CP020894.3\|WP_085662942.1\|1200834_1204236_+\|TM0106-family-RecB-like-putative-nuclease	gnl\|CDD\|274603	TIGR03491, TIGR03491, RecB family nuclease, putative, TM0106 family. Members of this uncharacterized protein family are found broadly but sporadically among bacteria. The N-terminal region is homologous to the Cas4 protein of CRISPR systems, although this protein family shows no signs of association with CRISPR repeats.	2.45186e-63
NZ_CP020894.3\|WP_003632344.1\|1204979_1205882_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|377216	pfam04072, LCM, Leucine carboxyl methyltransferase. Family of leucine carboxyl methyltransferases EC:2.1.1.-. This family may need divides a the full alignment contains a significantly shorter mouse sequence.	1.64366e-30

>NZ_CP020894.3|WP_080619801.1|1188107_1188341_+|Tn3-family-transposase
MGLATNAIVLWNTVYMQAAVDYLRAQGEVINEEDEKRLSPLGLKYVNLLGYFSFMLPKVVAEGQLRPLNVAEKLGLA
>NZ_CP020894.3|WP_085662938.1|1186426_1186651_-|hypothetical-protein
MEELAGCALLVFPALEIIAANGSLIHNDDTVLRIIDTIRHNRLNPDKKRTGIYTTVLLAQNSAHKIALFYNSHC
>NZ_CP020894.3|WP_105166095.1|1185465_1186038_-|ATP-binding-cassette-domain-containing-protein
MSKGNVEIDDINLTCFTKDSLRSQIAIVPQHLNLFHRSIFENIAYGCRHVSKEEVIAAAKKAKCHDFITSLEHQYETIIGEQGVKLSGGQRQRIAIARAILKNAPILLFDEATSALDSATEQAIQEALETLLKDKTALIIAHRLSTLKAMDKILVLENGPIVESGSHNELLAVKEAYYNYWTQQSSEFIR
>NZ_CP020894.3|WP_003632364.1|1183113_1184136_+|aminoglycoside-phosphotransferase-family-protein
MLIKPDLKDEEIVRCLRNVYGLDVDKIFFLPLGADLNTAVYRVTTSTERDYFLKLRSGEFNEASVLVPKYLADLGFRQVIPPLTTTDGQFWTSLASFKVVIYPYVKGRNGVEVNLSDKQWIEFGATMKRFHSADIPQTITTGVQTETFSSKWHQTVRVFLGRIDNEVFEEPIATKMALFLKSQKGEILELIRCAEHLASKLQKQPHENILCHADIHGWNLFIDEGGALYVVDWDTLLFAPKERDLMFIGSGLGDSGRTPFEDEALFYNGYGPTNINDDAIAYYRCQRVIEDIGVYCEQIFLSDEGGEDRLQSFKYLQSNFLPNGTIERAFQSCKSRENQK
>NZ_CP020894.3|WP_003632366.1|1181257_1182391_+|ABC-transporter-permease
MARFSLFRLHGLVVKEFVQLKRDRFTMALIIGLPIIQLLLFGLAINVNPKHLPTALMNYDQGPFARTLIHGLENTNYFKFVYFPHTEKEAQYLLSTNQVKFILTIPSDFSRKLIRKEHPAALLEADGTDPVSVVYALSASNNLMSTVFNNDLIGSIHEPIQHQTPAELRTHINYNASAITQYNIVPGLLGLVLSMTFVMVSAMALARERERGNWECLLATSLKPLEVMIGKSLPLIVIGYLQVFIILIIAVSFFRIPFLGSLWLFLLIILPFILANLFVGILFSTFAKNQLEASQLSTLFMMPSLLLSGFAFPFKGMPYWAQFIGNLLPLTHFNNIVRGMMLKGIGFHEVMIDLGPILLFMCVSLFLALRFYKQTLD
>NZ_CP020894.3|WP_012978948.1|1180330_1181257_+|ABC-transporter-ATP-binding-protein
MQVMNEQWIIDVYGLSKQFNGKMAVNELSLQIKQGEIFGFLGSNGSGKTTTIRMLCGLIQPDKGRGTCLGYDVISQAALIKSSLGYVPQTFSLYQDLTVEENLKFIARANNEKNYLNRINEIIGDLNLHPYRNVLAGNLSGGWKQQVSLAAALIHQPRLLLLDEPTSGVDPKTRQAFWSYISYLTTTGITVLVSTHYMDEAEKCNRLAYIVNGELMIQGTLDQMMQQVKLFAFLVEGSNLAHLANELQNKSQVEQVVHWGNSLRVCDSNAFLLKELIDAYPNYQWNAVTANLEEVFIHLVHSKISKGR
>NZ_CP020894.3|WP_012978947.1|1179501_1180347_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MLRCVFFLLIISLMNCSCSRQPLKQVNGYVEGRYTYIATSVSGRLIRLNVTRGTPVKRGQLLFNLEVEPELKEEQIAHARVKQAQNARDAIIAKLAYAKVTYERNKKLIEIKAIQQSLLDQEKSKYDVLLAQLAQAEDDLSALSLNLKQAQWRLQQNNSVAPIDGMVFDIYYRIGEYTHANQAVLSLLAPEDVKAIFYVNGLDVSALQLGQQISVFNAGHKESYKAQIDYISPSVEFTPPVIYSDQTHEKLTYRIEAKFRTQDAFHVHPGQPVTINYASHE
>NZ_CP020894.3|WP_003632369.1|1178213_1179509_+|LLM-class-flavin-dependent-oxidoreductase
MYDTPFFEDWLITHIADELEVNPDEILIDVPLAQLGLDSQTAITISGNLEILLETRLEPTLLFEYPTIQDLARYLATIKPITPGKKQALDFTLFFFALQDPVEGKYELIKKAVQFADQHGFKAVWIPERHFNAMGGNFPNPSVISAALATMTKQLSLRAGSVVLPLHDPLRVVEEWSVVDQLSQGRVELSFASGWHVDDFVLAPENYEQRKEYLLSQIPIVRQLWKGDAITRVNGHGNSIQVRSFPRPIQRELPVWLTAIGNPDTFRQAAEIDAHILTCLLTQDLTELASKIKLYRNTLARHHFKPKKVSLFLHTFVGESVVEARTSVLEPFRTYLRGTIELLANYSQHGDVALDVNQFSDEQKEELFDFAFERYLQERSLIGDMEQCQTMLNKVKEADVNEVACIIDFGLSSESVLASLERLNQLREANA
>NZ_CP020894.3|WP_003632370.1|1176575_1178213_+|fatty-acyl-AMP-ligase
MNYKQNYLNLGAILAEAVSKAPNHLYARYLKDGEREEVCLYFEQIYSKAQGLAAYLQSQIKQGARVILLFNSGLEFLIAFWGCILGGFIAVPANTPRDERSWRRIVNLIKDAQAELVLTTEDFAENPYLSIVRISLVNYHDSYLGYSFTRPNLHSDHIAFLQYTSGSTADPKGVIITHDNVIHNAKMIATALNAVHEGLNLVSWLPHYHDMGLLGCIITPALYQSTLTFMSPLHFLQRPARWLKAISRYQARVSVGPNFAYRLCTKKIKAHELEGIDLSTWTIALNGAEPVYEKTLEQFADAFAAYGFRKQSFFPTYGLAEATLFVSGGPTTETPKTMSMVVDNHSKTYVSCGKPGLGLSLAIIDPETNQSLVDNQVGEICISGTNVTQGYWRRPELNHNLFIDLAGRVFLKTGDLGFIKEGELYVCGRSKDLIIIRGRNIHAHDLEQSVIDCHSLLKAGIVAFGVTRDELEEVVLLVEMRPNTHHNDLCEVRKVVLETLLSEHGIEAQVVFIAKGSLLKTSSGKLKRAQCKQLYLAGALDVIGK
>NZ_CP020894.3|WP_085662937.1|1166648_1176497_-|hybrid-non-ribosomal-peptide-synthetase/type-I-polyketide-synthase
MKYSTNNDLLALVGIGLRLPGAKHPEAFWELLTKEICTVNKKSRPGLMQAEYYSLLENIDQFDADFFNIPANEAQAMDPQQRLLLEVSVEALHDAHIKPSSTKGKKIGVFVGISNADYSAITFANPSLIDAYALTGISPSICSNRIAYFFDWHGPALTIDTACSSSLTALHLARTSLLNGEANAALVAGANLILTPHVQAGYAQAAALSPEGLCRAFDAGANGVVRGEGVAAVYLKRLEDAKADGDRIYCVIAGTGVAQDGQTNGLTAPNPLGQKRAIQAALNAAGIKPHQIDYVETHGTGTLLGDPVEAKALAEVYSELRPQGQVLKIGSVKTNLGHLEAAAGLFGFIKAALCIYKKQLVASLHFANPNPYIPFTEYKLAVQTQNEAWVSDTYCAGVSSFGFGGTNVHIIALADRASPAQEKPFQSYPLKSYILPISAKNNPGLSVGLESWKQTLNQIPVSQWHHQIANGVRSYDEMNYRNAYVFRNKEELQQLLPSAVQKKRRSQPKVAFIFSGMGSQSLAMGRVLLTIHPFREAIIQCDKVLKELLNWSLYSILKGNSSMNPEDNPEVAQVLIFSIQIALFETFKCFGVKPTAVVGSSMGEVAAAYAAGYFDLKTAAHLFVTRIRLLVSRIDTGAIAVVFLSPQEASEWVVQFPKLWLAAHNAPNQVLIAGDINSIDQLLARLENEKINAKKLKGGSAPSHTPLINPIKKDFFHLLSSLTTQTPHTSFYSTVTGAKYQDSLDQEYWWKNLSGPIHYLEAISSLEKEQQPIYIELSPHPVLIANTLAIVQGAREEVELLPCLTREDTDEVTFLNCLGQLYKANSSINWEILYPPCYQDPSLALPMYPWNHHSYWKEQPKTQVAVQEQDSASYSDYPLRQTVLSLREKLKQTLWLEEYLSNKLAQALKIPQTNIQLDQSLKDLGIGSLIGMDLYNRLKNDFGVTMPIAFFLSGPSLKNIAQEVLTKLLETPTALRITKQPNQTNVLLSFGQERLLFIQQLIDKPYVYHIPIRIELTGQLNIEALKQAFAGLLARHQILRTVYQKDQGQFNAVVVPQSDFDFHHQQLDFSNEEELTRTLYECAIKPFNYANQALLRVHVFTLMTNPDRHTLILTIHHLVADGWGLKVLLHDLTLLYNHQLNQNTPPPKPLPFQFSDYAFWQKQQWQQGAWENQLNYWQERLENCPIESSFALDEPRPEQQSFNGERRVFIITQQEKKNIDAFCTAQGITPFMLLTTLVGILLYRTTGHTDIVLGTPVAGRQEPGTEQLVGCLLNMIPLRLQFEPQEPVSSLLNLVNQEVVNALAHQEIPLEKILEALEVPRRLSHSPLFQVVVAFHAPVPLQQFATLTAHLIDLDLKTAKFDVSFSFIEKEETLEGVIEYNTDLFTQTTVEHWLIAFHNVLHAILNSVTEYTIDSLPLEDPLKLEHRIQTIKKELAGKSHYCPILVTQHVSYQIAQCPDAIAISNDTDSWTYNELQQMAERCAYQLQQSSIKAHTIALCMPAGLELIAVQWASWLINACFVSIDPNLSSTQINQILTSTKADCIIYQTECPDVKIPALSWDKIKATKNKSPLLLSKIIPEDKAYLMLTSGTTGTPKVIEITHASLAHLVNWHLETYKNTSHSQCSQLAGISFDASLWEIWTALSAGSTLHIPNPEIKHDLHHLHQWIHEKQISHCFLPTPLFELCSDLDWRQSNLEYVFTGGDRLRIWPNSNWPCQVINHYGPAECTVVSSSLNLTEKKKPTATHPGIGKAIGYNVLLLLNAAQQPVPPGFIGEIYIAGPSVGLGYRTPDKNHSFIPNLFGSGILYKTGDFARQDKYGFFEFLGRRDQQIKINGVRIELAEIELIISTLPYIQQVELLVLEEKQLACFITLKEHPGTPPITEIPNHVKAAIKQQLGPYKVPGLIQVLEKMPVTANGKIDRKRLALQTCPIEKSVIDPNNTIVNRLLTLLKTVLKNEKITPDSHFFAYGGNSILAMQFIALIQQHFHIELSVKELFANPNLHQMAQIIEARQKTRIPALIPDPEQHYVPFPLTDIQQAYWIGRRSDLAGGGVSAQIYLEIDAHTLDIKYLQQAVNGLIARHAMLRTLINDEGLQYTLEKVPGYVIETHDLSQSPNWLLEQRNHLSHHYFNANQWPLFRLSISTDYQQFYRIHFNIDGLIADAHSLKILLDDLWNLYQGKSLIPLSLSFRDYLIYTITQLPPKEESKQYWLKRLSYIAQAPQLPLLNKVVSQPVFKRKSKIVPANIWGALKEQAKNHHLSPSTVLLTAFSTVLARWSEHPEFTLMLTVFNRRMVHPEVSSIVGDFTTVLPFSTSVSYHQPFIQYAKEIQDTVLDNLEHSDVGGIWILRELHKQGKGPFPVVFTSFLSEDFDTQATPFGTIAYSLTQTPQVWLDHQVSEYQGELHFNWDYNAPLFAKKTIEDLFLAYCDLLERLAENAALWEREKLDIGHPKLRQSLQQATHLTPVPASNMDLYSLFERHEHDDAEALITPTQSITYKKLHDLVKQGRTVLQHYGIQIGDKVALCLPKSIEQIAAVLAILAEGACFVPLGLNQPNHRMDHILKQAQARFLLVHEEHALQEKLITIYWTKELSQAQPCTTPRASSNPKSLAYIIFTSGSTGMPKGVQIQHQAVVPTLLAVNELVKLNTKDTILYSADLSFDLAIYDIFGAFLAKARTAIPEAIENKNIDELASFARRASVSIWNSVPTLFHMYFGLATKQKQYEIPSLRCVLLSGDWLCVKMCQQVRSQLPYVRLISLGGATEASIWSIYYPIDKVDPHWQSIPYGTALPGQQVLVYNNQMELCPPLVSGNLYIAGVGLSLGYTNDPTMNSKKFIEHQGIRLYDTGDRGRYLPDFSVEFLGRRDNQVKIQGYRIELGEIEHQLKMSPAIKEAIVLASGKPREEKTLVAYIECYDVQQNLEELNLAEYLTHYLPFYMIPRCFIKQEYWPLNSNGKIDRKQLPEPQTTSIIKQPIKETAVKEQLRTIIQSILKINDLEDEKEFLTLGANSIDLVLISNRLQEQFGFSPGMSEMFRLKNLELLTQYYQEHQGRNKTIHRSLLAGKEREQFKLSKKWIRALVGEQITLHPEGAVHPIKTQSSRQFAGKPLSKQQLTQLLAILSQSQQGQEFKAHYPSAGSLFPVQTYLMIKKNSVEDIDQGVYYFHPLENQLIKLNTQTARADQVHLAMNIPIGEQSCCSLFFFNSLDAIEPLYAESSLQYGLIEAGAMTQLLRMHASTLKIGICSIGQVNIDLIKTLAQLNSRYQFLHALEVGTLITEEQSEAWEELTF
>NZ_CP020894.3|WP_085662939.1|1190542_1191709_-|GTPase
MAGPYNTHTIVNVFRSIVQLISQYQELLHTQGIFRIPGSKEEIERLLEQLIGDHFNVEVLSNYIMNENTVNNEHLHNVLGMISAMLKESQILASTDDLLVSFSKKLKSLLESHQEEDIKNTIAAQLLDNLISDLLLSKRIDHQRAGEILYHYFHLMHQVGKYQEINFMTYNNLAIIIAPGLTNELSLYTGNNLLDLTSYVSQLTPVLENYIAETKWDCDFKKYHADKLDHLENTRYSLREQLEHMKEASRKSVTTPMKSYMLQASMIKAQIDAIKEVQQDHSLKKKAKKKLGKQLDPLQEEQSDLLSKISELAPKIKAMNSGQQQIQKEIDMLTHSGNRVTSCENPSNNSNLVQFSIFEPSSSNACTVLPTIPEEKEEFEDQEEYIHQ
>NZ_CP020894.3|WP_003632353.1|1192017_1192449_+|hypothetical-protein
MDTNIELNAMNPSESRSNEEIGTTDEVVNATSEDVYKYQKISLLIPKLITTIEQIEMLDQNTEMNIELKKSRKRLASIVIDNTSPNAEDIKEFTDSLSSALYGLSTGMSLIDMRGMIPEKKNRAVDLFADISLIQEDIVKLAS
>NZ_CP020894.3|WP_085662940.1|1192646_1195802_+|hypothetical-protein
MPTTRKLDWNKVALAAKKLGKEIGTALMGVITTPLNAIGATAEFAKETGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQKTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNGLVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWLQNTGWPAVKSGAETAYTSTKNGLVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPAVKSGAETAYTSTKNALVQAGNWIQNTGWPDVKSAAQNAFKAARDFCSSKISQLSDKVAELHDKAVEKIDKYLDDYLADDGGGLLLSSPKSSSSVTNILSDDAYTSPGTSRDNVSEKDNDKGNTIERRLG
>NZ_CP020894.3|WP_012978952.1|1196113_1197721_+|murein-biosynthesis-integral-membrane-protein-MurJ
MSNDKTLNVKATGTVALAIMVSRVLGLIREVLFNALFGSAAMGIFLIAFRAPNLLRDLFAEGALSVSFITVFSKKIETEGDQSAWQLASKMLTLTSIFMSVLCLLGIIFAKYIIFILAPGFSANDIETTVFLTQLMFPFILLVSLAAIVMGMLNSKNVFGVPALASSFFNMGSILGGALCGWLIDPSFGERALIGLSVGTVIGGLLQLGVQFPSLRKVGFRFRPNFHWYDSGIRKTLILTIPAVIAASAVQVNVLINSGFASYLGKEAVTWLNSAFRLMQFPLGMLGVAIATITLPVVSRLAATSNHSQLGPTLARAIRLAIFLTMPAAVGLWFFANPIISFIYGHGKFHASDSLQTAYALQFYALGLVAYSCIKVLSPAFYAIDKKWSPMIVSFATIILNIILNYYLIFKLNMGHCGLALSTTVSATVNFLILYILMSRLHNMQNRYLCSTTLRCILAAATLGFVCQFIFAYGTDFLYHPSFWVRGVSLVISISFAASVYFAICVLLRVDEAKSIFIIIYQRFGSPVDLKSKQV
>NZ_CP020894.3|WP_085662941.1|1197853_1199869_+|GDSL-family-lipase
MAISKRESKKNLTHFVVFGDSLSDGKNMGEKFSFLGSWVKSLWLKALGLDKSPKERFTNGYTWADSFRATLISKFLNDDKIKNDSDHRFGKYNLNNADISDEVLSQSPFIRKRYTLDDVIAESRKVKRKQRVEDREEGHLFTAKQEGTPEDIINPGHIVDSTDIADAAIAHRYKTNAQRATLRNKMRLLNASTLQESSDDISDQIITDPRYSKYIQEYYSLDDGRTAQYNGQNFFANYSQGGATSYDYSWKGLFLSLLAPFTSIKLFFTRLIVSNLSKQVDQFLVDLEKQEDYEDKERTLITVFSGANDLITVNSEPTKEAANLAVQSNIDNIEKLLQQGFKNIMLCNLPDLSLTPRFQGTSREGQAHEITEYFNTQLEEKYKKLKEKYPSCSIDFFNINSIFTKIYTDVRDNPQSEYAQYFDSKKLKEAYKDSTDYTMTPERTSPGSKHMFWDDVHPTATMHALLMSEFYKNIDALGKYKITAPAEQSPEQLCKKFRQKYHEKLENSWFGFLSSNKELPINYKEPAKALNSILRFALDKNNKKADYIRRAMIDLGWWVNNEPNMCIPALADAMWVLDPTLARKLEAKLDPHLEQPHSNSPRMMMGALNAGVSRHKTVPPELALSPEVEKKLKMMQKLPNKNKESTLSQAKGNTTFETPKLSSKDNVLTFA
>NZ_CP020894.3|WP_003632349.1|1200155_1200392_-|hypothetical-protein
MAAIATFAAWIAGLHIQSIGKVSDFQAHSAKSAFALFIVFLGKHVLKKTLLLTQENFQNLLMMLYQCAIQAQHAAPQM
>NZ_CP020894.3|WP_085662942.1|1200834_1204236_+|TM0106-family-RecB-like-putative-nuclease
MYLESNQIVFSPSDLAQFMDSPFASWMDHLAVTNPEYLPSPDENNELLSVLHDMGNQHESEVLASFEAKGLTIANLRNRTDSYQATIDAMKNGVDVIYQAHLELLPFKGYADFLIKVQGKSIFGDYCYEVWDTKLAKYVKPNFLVQLSCYAEMLDVMQQARADHITIILGNKEQKRFRLNDYFYFYQNLKHQFLLLHQQFEPFKSPDPALSKSWGRWSTHAKNLLLKADHLIQVATITSGQIKKLNQAGIYTMTALANSDYKTVKGIKYELFEQLKAQAKIQKDSIGKDVPAYQLINHENGRKQGLALLPPKSKNDIFFDIEGFPLEDGGLEYLWGVTYFDENDQRRYMDFWAHDKDQEKESFRSFVEWVYKRWQQDLSMHIYHYASYEVTACRKLMSRYGVCEYEIDQLLRNGVFVDLYKIVKSALLIGEPRYSIKNVEHLYRAKRDTEVGSGGDSVVVYERWRENPDGDTWQTSKILNDIRSYNIDDCNSTQELVRWLREKQEACGISFLGQTELIEPEIKEEVNERIKLRDRLLKRALQLHSEGHELLSKLHSVMAWSIEFHRREAKPVFWRLFDRLGLSEEELFEDMDCLAYCQRTEKPPYKSTPKARNLVYEYSFDPDQEFKANAKEYYLLGNETPDGKNIKAICHNEGSDLDHGIIALQIKNEPDSLITLIPNEYIDPDPIPQAITKQAESFANGMLAQTAIVDFLGKSIPRIKDHTSGQAIAPSHDPERRLNEIIKAVVNLDNSYLTIQGPPGAGKTYTGKHLIAELIKKGKKVGVSSNSHKAINNLLINTAKYCQKMGIAGHFSCKSKTDSVIDDLNINVLENKDISSFLQPGCVVGTTAWGFSRDDLEHAFDYLFIDEAGQVSVANLIAMSRSTSNIILMGDQMQLGQPSQGSHPDDSGLSILDYLLHSTPTIPDSMGIFLGTTYRMHSAVNQFISEAIYEGKLETAPENDEQLITVPVGYNGILNKEAGIIPVPVIHEGNTQGSDEEVAQIFSLAHELLGRTFNDKRGRQRTIDWDDILFVAPYNFQVNKLKAALGDKARVGSVDKFQGQEAPIVFLSMCASSANESPRGVNFLFDKNRINVAISRAQCMAVIVYSPALLDSVPNNIEQIAMMNMFCQLVKNR
>NZ_CP020894.3|WP_003632345.1|1204249_1204966_+|alpha/beta-hydrolase
MKKGQTFILIHGAWHASWCWKPIAKELIAKGHKVLMPDLPGHGQKKQISSSIGFTDYVNSVIQLVQHQQEQVILVGHSMAGLIISAVAERIPEAIGELVFVAGYVPHDQKSLFSLALESESNNLTPFLIIDELLQEIRLQISADLINIFFNCCKRADAQKAMSRLQAQPIRPFNEPVQIGEKYTRTPKRSLVCRYDKALLLSDQLRMSREVTDNIIYLDADHAVYYSGAKLIVDELLK
>NZ_CP020894.3|WP_003632344.1|1204979_1205882_+|class-I-SAM-dependent-methyltransferase
MREKILKDHNVATTSLLANYWKNEAKSKENWLSLTQMQGTRENDLFKDPLMQNFVNEQVKEEAEQRLDKRMWLPLATRTRFFRQTVSDAVKNKEVKQVIILGSGFDTLPARKIKYTQQFGVRFFEIDQPQILKCKEQIYAEQCIHKNATYIPLDYVNGDLIAALTNNDIDFTKPTLILWEGNTFYLEKEDVLRILRDLSSKFSHMVITFDYMHTLMQTSTQQLDSSAKEKCLEKTLDEFASKKSPFKAFFEPGEIVSLCTKLGIQCVDHKTAAQLAKEYEVDQEPYYTAETYSMVTFEHK
>NZ_CP020894.3|WP_003632342.1|1206214_1207441_+|hypothetical-protein
MGLEIYTWKSSRKGLGFTTPVKSTLLGGNVGHAAVELTFPADEKGDELAKKYQDIRGLAISKRTEIVPEQQADGNYKPKEQINYFVYFSWWPGNSNGHHINSHRDDLEAEWRHEPSHKIKSYTKGYLYGENVPEDNKTNVKGSLVREKTITKVKEFSHAHLKHDIENDPAYKELTARKDALLAENKLLTDKLTNYMQEVKQARIENREPNKALDLTEAENAQCSMIPKEISRISAQIDLCKRDFEERHLSVGEAPAAIVRIPTTYDHNAPDFALDAEKILEEMASLSQSAVAYNYTKFNCSTTATQVVKAGIDDELKMTMEAGGFDVEKASKAYISTPTSFCAFSKKIQSELLHLNTKQDIVEQRQNDAPDRSPAIEIDFKARLRDITQESRKVEERNEVDTGFVRRR

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Crispr_ID: NZ_CP020894_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020894_2

2886509-2886607

Orphan

Consensus_repeat	Method
GTATTTGAGCCTTTTGTAAATAAAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020894_2

>merge|NZ_CP020894|2|2886509-2886607|CRISPRCasFinder
GTATTTGAGCCTTTTGTAAATAAAATTGTGAAAAACAAAGCAACTTTGATATTTAAGGGTGAAGACAAAAAAGTATTTGACCCTTTTGTAAATAAAATT

>NZ_CP020894|2|2|2886509-2886607|CRISPRCasFinder
GTATTTGAGCCTTTTGTAAATAAAATT	GTGAAAAACAAAGCAACTTTGATATTTAAGGGTGAAGACAAAAAA
GTATTTGACCCTTTTGTAAATAAAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020894.3\|WP_003635971.1\|2876626_2877823_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635957.1\|2884186_2885131_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375831
NZ_CP020894.3\|WP_003635951.1\|2887795_2888782_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635946.1\|2890441_2891677_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP020894.3\|WP_003635935.1\|2895780_2896665_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|379231
NZ_CP020894.3\|WP_003635961.1\|2882042_2883203_+\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|236039
NZ_CP020894.3\|WP_003635975.1\|2873973_2875377_+\|YdgA-family-protein	unknown	unknown	gnl\|CDD\|377603
NZ_CP020894.3\|WP_003635954.1\|2885313_2885550_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635939.1\|2893860_2894889_+\|HlyD-family-secretion-protein	unknown	unknown	gnl\|CDD\|224482
NZ_CP020894.3\|WP_085662547.1\|2894869_2895802_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_085662914.1\|2897716_2898145_-\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NZ_CP020894.3\|WP_003635967.1\|2879792_2881463_+\|response-regulator	unknown	unknown	gnl\|CDD\|236842
NZ_CP020894.3\|WP_003635963.1\|2881635_2881950_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635969.1\|2878046_2879432_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635959.1\|2883306_2884059_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635934.1\|2896680_2897202_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635931.1\|2899539_2901021_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635943.1\|2891878_2892346_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP020894.3\|WP_003635973.1\|2875467_2876508_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020894.3\|WP_003635941.1\|2892438_2893809_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455

Protein	Function_ID	Function_description	E-value
NZ_CP020894.3\|WP_003635939.1\|2893860_2894889_+\|HlyD-family-secretion-protein	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	3.63524e-47
NZ_CP020894.3\|WP_003635957.1\|2884186_2885131_+\|hypothetical-protein	gnl\|CDD\|375831	pfam18405, Serine_protease, Gammaproteobacterial serine protease. This family includes serine proteases such as L. pneumophila effector Lpg1137. Lpg1137, is a serine protease that targets the mitochondria-associated ER membrane (MAM) and degrades STX17 (syntaxin 17), a SNARE implicated in macroautophagy/autophagy as well as mitochondria dynamics and membrane trafficking in fed cells. Lpg1137 has a sequence (-Gly-Leu-Ser68-Gly-Gly-) that matches the consensus sequence for the active site of serine proteases (Gly-X-Ser-X-Gly/Ala, where X is any residue). It exhibits proteolytic activity toward STX17 in vitro, whereas an active site mutant in which Ser68 is replaced by Ala does not. Expressed Lpg1137 localizes to the MAM and mitochondria, in addition to the cytosol, and binds to STX17.	5.12006e-164
NZ_CP020894.3\|WP_085662914.1\|2897716_2898145_-\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	7.35268e-38
NZ_CP020894.3\|WP_003635967.1\|2879792_2881463_+\|response-regulator	gnl\|CDD\|236842	PRK11091, PRK11091, aerobic respiration control sensor protein ArcB; Provisional.	4.44117e-80
NZ_CP020894.3\|WP_003635946.1\|2890441_2891677_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.39758e-20
NZ_CP020894.3\|WP_003635935.1\|2895780_2896665_+\|FUSC-family-protein	gnl\|CDD\|379231	pfam13515, FUSC_2, Fusaric acid resistance protein-like.	7.48193e-16
NZ_CP020894.3\|WP_003635961.1\|2882042_2883203_+\|acetylornithine-deacetylase	gnl\|CDD\|236039	PRK07522, PRK07522, acetylornithine deacetylase; Provisional.	0
NZ_CP020894.3\|WP_003635975.1\|2873973_2875377_+\|YdgA-family-protein	gnl\|CDD\|377603	pfam06097, DUF945, Bacterial protein of unknown function (DUF945). This family consists of several hypothetical bacterial proteins of unknown function.	1.22278e-81
NZ_CP020894.3\|WP_003635943.1\|2891878_2892346_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	3.85138e-45
NZ_CP020894.3\|WP_003635941.1\|2892438_2893809_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.49094e-43

>NZ_CP020894.3|WP_003635954.1|2885313_2885550_+|hypothetical-protein
MISFFLKSGCNVIQTATKRSLIDATRSMSTAGIIFGGYYIYNKAASLFTHHHFFNNNSNKIDVKEISEYNNKSSISGS
>NZ_CP020894.3|WP_003635957.1|2884186_2885131_+|hypothetical-protein
MQAKTENNPGNQGLPFSPTPYFLANLGVKTAAISFSVSTLTQPFQAMLTRLQLNAPSGFNGGLFRSMYRGFVPYAIAGQKRGAVSVTAKQANKEVIEEEEIEIPGRQRWLGTFVFSQADLLISNALGGKSKLENAGIITKTNFKWSFANYWKLTGVNWGSRSFAGFVNFSALGFVGDYISSFYKFDNDFYNKLAGGATAGVIATIFTTIPNSYADRKVLATKVENGRLLTVSPFTMFSQAKSHVNSVGMKQALSHFVKVNFLKEVVVRSPMSALTFGIIFGLDDLMGPEPLKRVWPKFKEIDSEKTENNPAKKM
>NZ_CP020894.3|WP_003635959.1|2883306_2884059_+|hypothetical-protein
MKILYIPFHEENDLCIAAIMWKRTLSEENILIIQHGQPINYNALKNAAGTITLYVLAHGIDSLSQPFHLASHSIITSKTSQLDIEKIADRFNSDFVYLHHKINHIKLFFCNNKGNQELIAKRFNDNLILFNSPIDYYAGNITAPWQNKIKYSFFHGIWYKTSNVRKTLYQKIEPMDSDIKLSVKERSMREFLANAKQKRIDAVFQRQCKARQERIIKNRQKYTDKLRLDLKDTVEEATDELSNPNPQYLG
>NZ_CP020894.3|WP_003635961.1|2882042_2883203_+|acetylornithine-deacetylase
MNTIDWLTKLIAFDTTSRNSNLSLVEFLANALNDYQIKPIIIHDRKEPKANLLATIPAYNARFDGGIILSGHTDVVPVDGQDWDSDPFQATIKDDRIYGRGACDMKGFIAVIMSLIPQLKALKLEFPIHLAFSYDEEIGCRGAPHIIDKINALNYRPKACIVGEPTSMQPVTGHKGIHSYRCQIHGVAAHSSLTSQGCNAIEHAASLIRFLRDLANQFKSEGHKDESYDIPYTTISTNLIQGGNAYNTIPNLCEFVFEIRNLALDDSDRINKKIMNFIENELLPSMHQEQPSAQIILENIANAPGLEIQPSEAIVQGAQSICQSQKQSKVAYATEAGLFQNAHIPTIVCGPGSIEQAHRANEFIDLEQLYRCERFVIEMLKLPFLK
>NZ_CP020894.3|WP_003635963.1|2881635_2881950_-|hypothetical-protein
MKKLLLFAISLFMIFSMASYAGKVVIIGNPVILEKQGSVYYLSNRYTVTTSYYYVILDGQRQVCYMEKQPALSALNTKTIDVNYRGSSMTWICYPYDTNYFETP
>NZ_CP020894.3|WP_003635967.1|2879792_2881463_+|response-regulator
MDSKETNELQKIIDEKNNEIHQLTLSLEEERSKFKNELQAIHEYYDNIIALMPGHVYWLDKNNVFLGCNDLQAKNAQLKSRKDIVGKTNFDMPWRDQAEELNKVNQLVMETGIPHTAEEYAVMANGMGIYYSQKVPLRNQKNEVIGVLGISLDITERKKMEVALRRAKENAEVANQAKNEFIANMSHDIHTPLSGIVGMSKLLEEKEQNPERKQYARWIHESGEQLLELLNGVMDIVATDSLREDDVHEELFELRKNIQDIAHLVQPTLQMKKIKLNIEIDEAVPNTIITDATKIHRVLLNLVGNAIKFTDNGSVTIKVEVLSLENNYTQLRFSVIDTGIGIPAELQSKIFDRFFRAIPSYKSTHSGYGVGLHIAQKYLSLLGGEINLESEIGKGSTFYFTLTLKIGYNDKPTSNPITGSDSQKAASPLSPLVLLVEDNILSLHMIENVVEQAGYEFYSAIDGEHALELIETNDFDLIITDTDLSNLSGKNLVLCIRELENQLQKKPIPIIGLTTNTSIEAEKKYLRSGFNKILSKPIHLKVLQSVVNDLFSPKSK
>NZ_CP020894.3|WP_003635969.1|2878046_2879432_-|hypothetical-protein
MPKVRGPRDGKLITASFDGKEKSLFPSLKTTKDLVLLSIRGNEYCTGEYLGAIVQQAVATHQTPIDHSGAKGKATFLIADEIYWHNIKQMISSESEVEILKQEAIKIGADYFLTNLGAFLTPLDMTIEQFNEKYPEKSVDEIITIINQLADEQGKNFEIVRWKTWVAQNDSQEKINKMMGFYDSVEGLKESVIRTQNNFVKRHGKDGDEELWKLRSHDYLIEESPAVMWLAASLGYNFIVYPGEILPPFEATKEFFVVPNHVPRISQGKNIIEECEHNEYSIHTDNPNRLVNWLEVNFKRSHPPKQAGVSVENEVTSVGKSFASVEQPLVSVEKKMSFFSSSPRKKTKVRVLDKQVEDNVTMDLPLSNPNALMLGSALEGIGKALISKHSNGKIQSKSSSILSEAFAGITHEVLSSDLSPSDQVNFLVSILNGVMKGNGQSCTSESDTSILLENTKASFCK
>NZ_CP020894.3|WP_003635971.1|2876626_2877823_+|hypothetical-protein
MISMTAYWQQFKECIESLQMSTEDIEYARQMSTAKNLIETGLIIEKLGLLEIQQVSEQLHEKAKLFQNEICYTTDNHEHRFYLPKITNTQSFIFAIIYYQHLLNYQNVSYQGTINWFRPKVIDGINQKKITTAIQAQALLQEIRQYCQKISLNVDELLFLKKEEESIIEYTSRLIKTFGCQVKSPKTERKAHLPPLDDITTLEKSLEKLNHKWNQLKIKADLIDQKLSAFKHAKQDYFQLKKEWKNKWFFTKAFYWFISLFIEVSEIKNLKAAHEHLTQTQNDLKQELQNHTSKSYCSKLQKQLRKLEHEQTCLKGEITLKKEIQRQKEHKPKFELLTDKKLEKDIVATSDFKENESSYFETSSSNDYYGFFKNNLPSRYTLQAVAVGVAAIAIQNLL
>NZ_CP020894.3|WP_003635973.1|2875467_2876508_+|hypothetical-protein
MNITRDIINKAVEAKIITQKQSEELIAFIRKQPGQNKGFGLTNVLYYLGGLIAIGAMSLFMTLGWELFGGWGILFLCICYAILGLSLSDIFNKKGFIVPAEICATFVVFLTPLAIYGLQKGMGWWPPDDTVFREYNYYIKWHWIFMELGTLAVGIIMAWIYRYPFMIMPIAVTLWYMSMDFTAMLTGGESDFELSEKVSMYFGLIMLLIGFWVDFRSRQSEDYAYWLYLFGVLTFWCGLSAQHSDYELSKFIYLCINLILILIGIILSRKVFTVFGGIGVCLYLGHLAYDIFKDSYFFPIILTLIGLGIIYLGILWQKHEQKMTIAIRKILPKSLQELLQARDQLI
>NZ_CP020894.3|WP_003635975.1|2873973_2875377_+|YdgA-family-protein
MKKWIGYLLSLVVLVLIIYDLMGLMVQNTLGNIINKIPKNPIMTTKIDKFQHGWFSSKALWIFKMHIPAQTITDKNGVPKTEPPLDFEMTLPITIKHGPIIFTNDGIRFGIGTITTQPETHYGAFINYLNRIIIEYNLPSFGTHVKEVSNNEEFQFNWMGLSALLSISSNIDKLDSYLKLYGIDGSGNNSVFKIGEITYSFNSKRIQEWLWIGKSHFNISSISVTSNNQNILDLQEFDFILSSDIKNEALNFYCKLSLQKLLANNQNYSPAILKLSLKNLDPEIMAKLNKQTFNMLQTSDSHLVGLSLATELPKLLSKGSVLELSEMTINLPEGKIVGNFKISLPKTEINDLSKAMQQAHGQGYFKAPTTIVKELMTSSIKSNLSNVSQQIEQTSPTQDVSAQSPANPTSRTPDLDEEAKKQTNQILKKLVEKGFLKIKDKDYVLQFKLENQQLIVNGKLFTPDMLR
>NZ_CP020894.3|WP_003635951.1|2887795_2888782_+|hypothetical-protein
MLSRIEKPINLQKQLIILINPTKNDAMGSKLGLFLNHTLARGKALNATNSAIMIIKKEGTNQVEALDVKNYNFFDSELFSKDSPREKKLLIDFQDKMHPLDETASYDEIVIIGSGVPLKGSNTYASINGLRNNFFPSLVTCIKNIIGTHLKDNGHVRVQICHAATKSPIVTSDEMIQEQRPLSECIQVERKNFTIHAPSSYSVISPNDGRAIDVAFKGTSNQFDEFAKHVKKFLNYKNSNDYIRKMTQIFVLENEDKYHYTKIIKNLSIVNPQQEEFLIETAEDKVSFKKNKFGLFAKSASCKKSIPGEPEDAHSASEEMSLSNFFGN
>NZ_CP020894.3|WP_003635946.1|2890441_2891677_-|MFS-transporter
MSASRVVAWFVWVVASIFYAYQYVLRVMPNIMMDDITSQFHIDATVFGQFSGIYYLGYSLMHLPIGIMLDRFGPRKVMTVCILLPVIGLLPLIFADNWIYPLIGRALIGIGSSAAILGTFKIIRMSFKEQYFSRMLSFSVMIGLIGAVYGGGPVSYLSHTLGYKVVVEIFIILGLILACVTYLIVPEEKPTYHSSVFTNVKTVFSNKKVMLLCFFSGLMLGPLEGFSDVWGSGFLKHVYGLEPSVANYLPSMIFIGMCFGSPVLSLIAEKTGYYLGTIITAGIIMCLVFVALVAGTLTVTTITLSFVLVGMCCAYQILAIYKVSTYVPDNLAGLTTAIANMIIMTFGYGFHTVIGVVVNAYGGIRDANAFIYGIGVIPITLALGVTGILVLAYQDKFGTRRSVIKERLSKA
>NZ_CP020894.3|WP_003635943.1|2891878_2892346_+|Lrp/AsnC-family-transcriptional-regulator
MDRIDKKILDILQANCKINNQELADMVALSPSPCLRRVKLLEDHGYIKKEVALLDPEKIGLKLSVIVLVGLDNHQPTVMSHFEEEIRFLPEVIQCYMITGQSADYLLKVIVPDLNAYQTFLLDKLTRINGVSSVQSSFILRTICETTSLPLNHLE
>NZ_CP020894.3|WP_003635941.1|2892438_2893809_+|TolC-family-protein
MLKRISIFLLLIEIVTGCHRNVEQQVSTPLKKFPSSTKAYKPVNNLPYTAWWKQFHDLELNQLIETGLKNNMDIHIAIGNVQQAQGELQQIKLSWIPTLKLFAGYSTNPALGIPGAFYGVWPYYVLNIMQLYTQQKQATYNLQVYQAAVDGMRLALIGQITTAYFTLIAQMEQLRLLQQLDNDLKSLIALSQQDIKIGLVNEIDLAQLQSDEQIIAAQIKPILHNIVFSENALRFLINEIPGRVKNNNNFATLDFTRFKPGSLPATVLNNRPDMKMAEYALKASRIKISVAYSNFFPALQLDDFLGEVSSPHSTFAQSVDTYVNWTIAPSVLGNVAASKGAYHAKVAEFEKTVKRILKEVDTDYSANKRMNEQFVAYAQAEEDYRRKYKLQQGLLKTGLISYKDLLQSKIYLDNLALTTNQAKLELAMSLVALYQDLAGGYAYHLRPKKLQTDSST
>NZ_CP020894.3|WP_003635939.1|2893860_2894889_+|HlyD-family-secretion-protein
MKNFIQFRTKIKKRYTRLKRSITLVNTIIFIGILTTVIYIFSYLFPFTDNAFVVNNVRPVAALTSGYITDLYVQNGDVVKKGQKLFTVFQKPYIYTVEQLTADLASAQAQLAVLKTTYDRDLKLSENEQRNYIKLYQDDQKYRKGYRIKSVSLMTLQNSQQETQAAKDKWQAALKQLEIDKNQIEVQGNEIKSIYARLKNAKVNLELTNVYAQGNGIIQNLFFTIGTPVNINQPLFSLVDTDNVYIQANFNETDLRDVRKGSKVLIFPRMYLSRKVFHGVVESDYWSANRQLVDNRTQLQNVVNENQWILLPQRLPVIIRITDLDPHYPLRVGTSAYVYIKV
>NZ_CP020894.3|WP_085662547.1|2894869_2895802_+|hypothetical-protein
MSISKFKQWLDEVDPYAIQRITLYKSLFIATVEVYVYWLFQPVSFMAFFMPFLLTSLYEAPVLSTFKEKEQLLIFITIGIILISVTFYLVYPFRVIFFFFSVFVLSVTYFCVLRYFYTLKNLTMLLISSGALVLGIDPPANLEVVYGLISSIALSMTFIFICLRIFPNMYLIVWNRALQKFIQYLEKDIDYTINKNDNKPTWEEIMHLGIVRNYTKMLPKKYMMPAYRISVNIRNIQHSLDNLYYETMNEAFWYGIKNNLLWLRLQMHANSPCGLPQFPIKPNTRLQHHVAMCLDHAFSSWNKLCLLKMH
>NZ_CP020894.3|WP_003635935.1|2895780_2896665_+|FUSC-family-protein
MLTQNALKRKLDYARFVHLAIMFMVAMLIYLFSNIPHKWWVLLTVIVISAGIEPGLIVKRAIYRIGGTFAALLILIPLLYLTQFNYRLIPVIFIVAVIGFSVSSINTNRYDISVFFITLIAFFLLAQTTEINSPEGPFVMMLNRGICTLLGVAIVLIGDYFLFQTFHYSQKLYLFHQMMVYNFFNDVVQQITQTSPHRINSSIFVAKLRTQVIKICSPITVSSQNLKLEAKVSPQTIKRIDVFQETIWEIRRVLFALSVSEFVLHSPTTTQKHLQRFNTLMNKAKNNFIYIAEE
>NZ_CP020894.3|WP_003635934.1|2896680_2897202_-|hypothetical-protein
MSRFPNKTHYELRQYFKKLSLEQLKEQNRSYGPHFENLEEKIDKCSQDLAAESKHWQTLKDQKSTHELSYDSVVLSEQEFRQNIESLNDIMDHSERFLARKSVGVSPSELYYQQLSCLENPIQQSNLMIERLANKLEHLTKKKKEAISELKTLNSIIEEKEQLNNVPQVVHRY
>NZ_CP020894.3|WP_085662914.1|2897716_2898145_-|IS200/IS605-family-transposase
MTLKRASHCVYQTHYHIVFPVKYRKSLLSDEITSAIKSIAGEIGERYEIDFEQLGCDKNHIHILCSFHPKYSISEVVRKFKSITARELFKQFPLLKKDLWGGEFWSDGYYVSTVGERGDWRVVERYVKNQGKESETKQLRLI
>NZ_CP020894.3|WP_003635931.1|2899539_2901021_+|hypothetical-protein
MQSKYVSERPLIKTLFKQGLTKNKETPIETVSFTDTLQSADEHALSPEHLAPIGPGTTNTWIKKELILSEKTRLKYNVATCTAVDINDLGAKRLTDAYHQIRGLPGFVHRFLHGRPSLERALFVQAPEMYPIFDTPYDDSKTILMTNPAYLDIKKFLSDCEKVSTGYALKQLKNSENGLALVTWYIHPEALPAKFRNTLPAHKVLEYHRNQLIHEADFACKSKKGKQPFDYYRYGQEMTPLQLCGSFSKLPRTVSQDSITTLESRSESIYLACLFDLDQDKKQSLIYLTSLRDNILANLSTVYGVTPQDKIKIYLHMPYLEATTTLHVHVRVNQADHGLEDAKSFGINEIIDTLEKGGSVTDMILSRGTIYCSEYPIGENIEGVCVKTVPNIQRDWKDIFNLLKADKLTIAYLLQALQENAVKSRMQLLDLDQIGELLKIIEEIDEYPSIEELINILKRMEVNAELKKLGWSLETGTCIKQESHKNPPQALLG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1065495 : 1121497

Cronobacter_phage(16.67%)

tRNA,transposase,integrase

attL 1110633:1110650|attR 1128903:1128920

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012978931.1\|1065495_1065831_+\|tRNA	tRNA-binding protein	NA	NA	NA	NA
WP_105223260.1\|1065850_1066513_-	hypothetical protein	NA	NA	NA	NA
WP_003632400.1\|1066658_1068140_-	amino acid permease	NA	NA	NA	NA
WP_085662914.1\|1068388_1068817_+\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_085662877.1\|1069338_1069524_+	hypothetical protein	NA	NA	NA	NA
WP_085662878.1\|1069524_1070322_+	hypothetical protein	I6PD67	Cronobacter_phage	5.6e-20	30.2
WP_085662879.1\|1070738_1071491_+	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_085662880.1\|1071520_1072597_+	hypothetical protein	NA	NA	NA	NA
WP_085662881.1\|1072871_1074320_-	hypothetical protein	NA	NA	NA	NA
WP_085662882.1\|1075590_1076133_-	hypothetical protein	NA	NA	NA	NA
WP_125466281.1\|1076506_1076584_+	hypothetical protein	NA	NA	NA	NA
WP_085662883.1\|1076650_1077481_+	hypothetical protein	NA	NA	NA	NA
WP_085662884.1\|1077793_1078120_+	hypothetical protein	NA	NA	NA	NA
WP_085662885.1\|1078258_1078762_-	antirestriction protein ArdA	G9FHQ1	Rhodococcus_virus	2.8e-17	33.3
WP_085662886.1\|1079568_1080585_+	esterase family protein	NA	NA	NA	NA
WP_085662887.1\|1080716_1081616_-\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_085662888.1\|1081608_1082412_-\|integrase	integrase	NA	NA	NA	NA
WP_085662889.1\|1083043_1083400_-	hypothetical protein	NA	NA	NA	NA
WP_085662890.1\|1083648_1085583_-	type IV conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_085662891.1\|1085579_1085903_-	hypothetical protein	NA	NA	NA	NA
WP_172622898.1\|1085917_1086091_+	hypothetical protein	NA	NA	NA	NA
WP_085662892.1\|1086096_1087650_-	conjugal transfer protein TraG N-terminal domain-containing protein	NA	NA	NA	NA
WP_085662893.1\|1087662_1089021_-	integrating conjugative element protein	NA	NA	NA	NA
WP_085662894.1\|1089030_1090005_-	TIGR03756 family integrating conjugative element protein	NA	NA	NA	NA
WP_085662895.1\|1089997_1092757_-	conjugative transfer ATPase	NA	NA	NA	NA
WP_085662896.1\|1092766_1093114_-	TIGR03751 family conjugal transfer lipoprotein	NA	NA	NA	NA
WP_085662897.1\|1093070_1094330_-	TIGR03752 family integrating conjugative element protein	NA	NA	NA	NA
WP_085662898.1\|1094326_1095103_-	TIGR03749 family integrating conjugative element protein	NA	NA	NA	NA
WP_085662899.1\|1095089_1095746_-	DUF2895 family protein	NA	NA	NA	NA
WP_085662900.1\|1095738_1096101_-	TIGR03750 family conjugal transfer protein	NA	NA	NA	NA
WP_058463393.1\|1096113_1096479_-	hypothetical protein	NA	NA	NA	NA
WP_085662901.1\|1096475_1096742_-	hypothetical protein	NA	NA	NA	NA
WP_085662902.1\|1096741_1097068_-	hypothetical protein	NA	NA	NA	NA
WP_085662903.1\|1097077_1097713_-	TIGR03747 family integrating conjugative element membrane protein	NA	NA	NA	NA
WP_085662904.1\|1097703_1098135_-	integrating conjugative element protein	NA	NA	NA	NA
WP_085662905.1\|1098134_1098956_-	TIGR03759 family integrating conjugative element protein	NA	NA	NA	NA
WP_085662906.1\|1098948_1099533_-	hypothetical protein	NA	NA	NA	NA
WP_085662907.1\|1099529_1099943_-	hypothetical protein	NA	NA	NA	NA
WP_085662908.1\|1099935_1100166_-	carbon storage regulator	NA	NA	NA	NA
WP_085662909.1\|1100526_1101432_-	Vir protein	NA	NA	NA	NA
WP_085662910.1\|1101688_1103419_+	AAA family ATPase	NA	NA	NA	NA
WP_085662911.1\|1103459_1103732_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085662912.1\|1103785_1105762_+	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	3.4e-34	27.4
WP_085662914.1\|1106563_1106992_+\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_085662915.1\|1107143_1107440_+	hypothetical protein	NA	NA	NA	NA
WP_085662916.1\|1107439_1110745_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
1110633:1110650	attL	NA	NA	NA	NA
WP_011215181.1\|1111140_1111413_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_085662917.1\|1111488_1113240_+	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	2.3e-66	32.7
WP_085662918.1\|1113361_1114171_-\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_172622899.1\|1114820_1116539_+	ATP-binding protein	NA	NA	NA	NA
WP_085662920.1\|1116539_1117934_+	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_085663037.1\|1118306_1118582_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_085662921.1\|1118578_1118929_+	XRE family transcriptional regulator	A0A0D5BHH6	Escherichia_phage	2.6e-06	35.8
WP_085662922.1\|1118948_1119308_+	transcriptional regulator	NA	NA	NA	NA
WP_085662923.1\|1119376_1119631_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_085662924.1\|1120255_1121497_-\|integrase	tyrosine-type recombinase/integrase	A0A0R6PHM8	Moraxella_phage	2.0e-56	34.1
1128903:1128920	attR	NA	NA	NA	NA

DBSCAN-SWA_2

2223303 : 2276559

uncultured_virus(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085662449.1\|2223303_2223885_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	1.2e-19	33.3
WP_172622906.1\|2224060_2224234_+	hypothetical protein	NA	NA	NA	NA
WP_080619749.1\|2225115_2225658_+	hypothetical protein	NA	NA	NA	NA
WP_165391558.1\|2226203_2226506_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_080619747.1\|2226498_2226888_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_080619746.1\|2227087_2228110_-	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_080619745.1\|2228183_2228540_-\|transposase	transposase	NA	NA	NA	NA
WP_085662451.1\|2228559_2228838_-	hypothetical protein	NA	NA	NA	NA
WP_165391555.1\|2229588_2229753_-	hypothetical protein	NA	NA	NA	NA
WP_085662453.1\|2229749_2232509_-	cation-transporting P-type ATPase	M1HLC0	Paramecium_bursaria_Chlorella_virus	8.6e-68	27.6
WP_085662455.1\|2232525_2233464_-	universal stress protein	NA	NA	NA	NA
WP_085662457.1\|2233542_2234283_-	acetoacetyl-CoA reductase	NA	NA	NA	NA
WP_085662459.1\|2234334_2235489_-	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	2.2e-78	46.6
WP_080619740.1\|2235681_2236425_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_080619969.1\|2236843_2237527_+	L,D-transpeptidase	NA	NA	NA	NA
WP_085662461.1\|2238137_2238455_-\|transposase	transposase	A0A218MNC9	uncultured_virus	2.3e-09	38.6
WP_165391563.1\|2239311_2239653_+	recombination-associated protein RdgC	NA	NA	NA	NA
WP_085662465.1\|2239653_2239992_+	recombination-associated protein RdgC	NA	NA	NA	NA
WP_085662467.1\|2240206_2240845_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_080619735.1\|2241040_2242582_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_085662461.1\|2242815_2243133_+\|transposase	transposase	A0A218MNC9	uncultured_virus	2.3e-09	38.6
WP_105166017.1\|2243203_2243641_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_085662469.1\|2244053_2246453_+	SidC	NA	NA	NA	NA
WP_085662471.1\|2247580_2248486_+	DNA polymerase III subunit epsilon	A0A223W0B0	Agrobacterium_phage	4.0e-30	36.6
WP_080619968.1\|2248549_2248807_+	YheU family protein	NA	NA	NA	NA
WP_080619730.1\|2248924_2249842_-	bifunctional helix-turn-helix transcriptional regulator/GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_085662473.1\|2252178_2253306_+	DUF4424 domain-containing protein	NA	NA	NA	NA
WP_080619728.1\|2253876_2254209_-	hypothetical protein	NA	NA	NA	NA
WP_172622907.1\|2254874_2255792_+	DUF4238 domain-containing protein	A0A0F7LBR6	Escherichia_phage	3.7e-44	35.0
WP_080619725.1\|2256256_2256976_-	endonuclease	NA	NA	NA	NA
WP_125461271.1\|2257829_2261141_-	hypothetical protein	NA	NA	NA	NA
WP_165391560.1\|2261372_2261543_-	hypothetical protein	NA	NA	NA	NA
WP_080619723.1\|2261551_2262616_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_125466274.1\|2262618_2263842_-	ATP-binding cassette domain-containing protein	F2Y1V5	Organic_Lake_phycodnavirus	7.3e-19	28.3
WP_085662479.1\|2263916_2264828_-	hypothetical protein	NA	NA	NA	NA
WP_125461270.1\|2265479_2265701_+	hypothetical protein	NA	NA	NA	NA
WP_080619720.1\|2266006_2266513_+	hypothetical protein	NA	NA	NA	NA
WP_080619719.1\|2266900_2267761_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_080619718.1\|2268201_2269314_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_080619717.1\|2269332_2270505_-	cation:proton antiporter	NA	NA	NA	NA
WP_080619716.1\|2271193_2272240_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_085662481.1\|2272321_2273608_-	H(+)/Cl(-) exchange transporter ClcA	NA	NA	NA	NA
WP_003636919.1\|2273947_2274886_+	hypothetical protein	NA	NA	NA	NA
WP_003636918.1\|2275276_2275696_+	TIGR03792 family protein	NA	NA	NA	NA
WP_003636916.1\|2276394_2276559_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

2434024 : 2440841

Acinetobacter_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003636739.1\|2434024_2434822_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.1e-23	34.2
WP_003636738.1\|2434955_2435918_+	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	4.2e-38	32.1
WP_003636736.1\|2435917_2436445_+	HAD-IIIA family hydrolase	A0A140XBD6	Dickeya_phage	1.4e-24	47.1
WP_003636734.1\|2436441_2437014_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_003636733.1\|2436994_2437537_+	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_003636730.1\|2437533_2438259_+	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.3e-19	26.0
WP_003636726.1\|2438478_2439045_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.5e-56	53.2
WP_003636725.1\|2439034_2440069_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	4.6e-75	45.9
WP_003636724.1\|2440061_2440841_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	5.1e-58	52.0

DBSCAN-SWA_4

2994040 : 3003290

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003635765.1\|2994040_2995723_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	1.3e-18	29.1
WP_003635764.1\|2996056_2997382_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	2.8e-48	31.9
WP_003635763.1\|2997392_2998541_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.6e-127	59.2
WP_003635762.1\|2998649_2999762_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	1.7e-51	35.3
WP_085662568.1\|2999897_3001037_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	1.3e-25	36.4
WP_003635760.1\|3001340_3003290_-	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.5e-146	49.4

DBSCAN-SWA_5

3209060 : 3276794

uncultured_Mediterranean_phage(20.0%)

tRNA,transposase,protease,integrase

attL 3196884:3196908|attR 3233759:3233783

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3196884:3196908	attL	NA	NA	NA	NA
WP_003636923.1\|3209060_3209954_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_105223258.1\|3210094_3210994_+	reverse transcriptase	NA	NA	NA	NA
WP_085662596.1\|3211260_3213672_-	SidC	NA	NA	NA	NA
WP_085662598.1\|3214084_3216271_-	DUF1738 domain-containing protein	A0A1B1IRD0	uncultured_Mediterranean_phage	3.4e-35	33.6
WP_019349995.1\|3216263_3216428_-	hypothetical protein	NA	NA	NA	NA
WP_085662600.1\|3216424_3216970_-	conjugative transfer signal peptidase TraF	NA	NA	NA	NA
WP_085662602.1\|3216966_3218856_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_085662604.1\|3218852_3220235_-	P-type conjugative transfer protein TrbL	NA	NA	NA	NA
WP_085662606.1\|3220239_3220452_-	hypothetical protein	NA	NA	NA	NA
WP_085662608.1\|3220475_3221216_-	P-type conjugative transfer protein TrbJ	NA	NA	NA	NA
WP_085662610.1\|3221227_3222475_-	TrbI/VirB10 family protein	NA	NA	NA	NA
WP_085662612.1\|3222480_3222888_-	conjugal transfer protein TrbH	NA	NA	NA	NA
WP_085662614.1\|3222890_3223766_-	P-type conjugative transfer protein TrbG	NA	NA	NA	NA
WP_085662616.1\|3223762_3224461_-	conjugal transfer protein TrbF	NA	NA	NA	NA
WP_085662618.1\|3224457_3226992_-	conjugal transfer protein TrbE	NA	NA	NA	NA
WP_058450406.1\|3226988_3227288_-	VirB3 family type IV secretion system protein	NA	NA	NA	NA
WP_058450407.1\|3227284_3227662_-	TrbC/VirB2 family protein	NA	NA	NA	NA
WP_085662620.1\|3227673_3228639_-	P-type conjugative transfer ATPase TrbB	NA	NA	NA	NA
WP_085662622.1\|3228658_3228931_-	carbon storage regulator	A0A0U1UNS3	Pseudomonas_phage	7.7e-06	51.0
WP_058481199.1\|3228950_3229259_-	hypothetical protein	NA	NA	NA	NA
WP_085662624.1\|3229263_3230145_-	Vir protein	NA	NA	NA	NA
WP_085662626.1\|3230329_3231004_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085662628.1\|3231104_3231524_-	hypothetical protein	NA	NA	NA	NA
WP_058481195.1\|3231527_3232751_-\|integrase	site-specific integrase	Q9T1P3	Pseudomonas_phage	6.4e-23	28.7
WP_085662630.1\|3232753_3233488_-	Abi family protein	NA	NA	NA	NA
WP_080619950.1\|3233935_3234205_-	hypothetical protein	NA	NA	NA	NA
3233759:3233783	attR	NA	NA	NA	NA
WP_012979348.1\|3234500_3236132_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_085662632.1\|3236621_3239402_-	hypothetical protein	NA	NA	NA	NA
WP_003635412.1\|3240458_3242312_+	peptidase M4 family protein	NA	NA	NA	NA
WP_012979349.1\|3242565_3243312_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_003635408.1\|3243654_3243867_+	ORF6N domain-containing protein	NA	NA	NA	NA
WP_003635403.1\|3244112_3245282_+	tetracycline destructase Tet(56)	NA	NA	NA	NA
WP_003635401.1\|3245511_3246135_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_012979350.1\|3246605_3247280_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_003635395.1\|3247703_3248552_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003635393.1\|3248721_3248949_-	ChaB family protein	A5IZT6	Spodoptera_litura_granulovirus	1.3e-09	42.7
WP_003635391.1\|3249126_3249411_-	DUF3175 domain-containing protein	A0A0F6TH17	Sinorhizobium_phage	4.7e-22	66.3
WP_003635390.1\|3249709_3250207_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012979352.1\|3250341_3251946_-	hypothetical protein	NA	NA	NA	NA
WP_012979353.1\|3252275_3253046_+	hypothetical protein	NA	NA	NA	NA
WP_003635384.1\|3253088_3254375_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.6e-96	46.2
WP_003635381.1\|3254567_3255338_-	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_003635379.1\|3255334_3255787_-	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_003635377.1\|3255942_3256986_-	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_003635375.1\|3257000_3257501_-	OmpH family outer membrane protein	NA	NA	NA	NA
WP_003635373.1\|3257668_3259981_-	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_003635371.1\|3260115_3261468_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003635370.1\|3261631_3262414_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003635368.1\|3262442_3263201_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	2.0e-22	40.3
WP_003635363.1\|3263573_3265115_+	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_012979354.1\|3265107_3266331_+	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_003635359.1\|3266421_3267774_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	3.6e-19	26.3
WP_003635356.1\|3267963_3268806_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_012979355.1\|3268919_3269495_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003635352.1\|3269626_3270292_+	hypothetical protein	NA	NA	NA	NA
WP_012979356.1\|3270451_3271180_-	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012979357.1\|3271374_3272859_+	hypothetical protein	NA	NA	NA	NA
WP_003635346.1\|3273355_3274654_-	adenylosuccinate synthase	A0A285PX35	Cedratvirus	5.3e-68	34.1
WP_003635344.1\|3274740_3275655_-\|protease	protease modulator HflC	R4VJU7	Alteromonas_phage	1.5e-05	26.3
WP_003635342.1\|3275657_3276794_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020895

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP020894

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection