CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP015612	Stenotrophomonas maltophilia strain OUC_Est10, complete genome	12 crisprs	DEDDh,WYL,csa3,cas3,Cas9_archaeal,DinG	1	3	3	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015612_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_1

135191-135296

Orphan

Consensus_repeat	Method
GTGGGTGCCGACCGTTGGTCGGCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_1

>merge|NZ_CP015612|1|135191-135296|CRISPRCasFinder
GTGGGTGCCGACCGTTGGTCGGCACTTCTACTGTTCTGGTGGGTGCCAAGCTTGCTTGGCACTGGGTCTGGGTCTGCTCTGGTGGGTGCCGACCGTTGGTCGGCAC

>NZ_CP015612|1|1|135191-135296|CRISPRCasFinder
GTGGGTGCCGACCGTTGGTCGGCAC	TTCTACTGTTCTGGTGGGTGCCAAGCTTGCTTGGCACTGGGTCTGGGTCTGCTCTG
GTGGGTGCCGACCGTTGGTCGGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088023180.1\|137855_138152_-\|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|274228
NZ_CP015612.1\|WP_049435403.1\|137477_137792_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088023169.1\|129082_129544_-\|META-domain-containing-protein	unknown	unknown	gnl\|CDD\|225728
NZ_CP015612.1\|WP_088023163.1\|126266_128336_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP015612.1\|WP_088023184.1\|139640_141089_+\|nitrogen-regulation-protein-NR(I)	unknown	unknown	gnl\|CDD\|273818
NZ_CP015612.1\|WP_088023189.1\|141783_142410_+\|superoxide-dismutase-family-protein	unknown	unknown	gnl\|CDD\|376292
NZ_CP015612.1\|WP_004134334.1\|133370_133709_+\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|223424
NZ_CP015612.1\|WP_088023182.1\|138165_138447_-\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|226079
NZ_CP015612.1\|WP_088023192.1\|142657_143545_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088023176.1\|133730_135161_+\|ammonium-transporter	unknown	unknown	gnl\|CDD\|182630
NZ_CP015612.1\|WP_014035517.1\|138586_139648_+\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226370
NZ_CP015612.1\|WP_004153533.1\|131628_133038_+\|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl\|CDD\|181884
NZ_CP015612.1\|WP_088023166.1\|128346_128958_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP015612.1\|WP_088023172.1\|129711_130536_-\|META-and-DUF4377-domain-containing-protein	unknown	unknown	gnl\|CDD\|379548
NZ_CP015612.1\|WP_088023178.1\|135387_136134_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|225567
NZ_CP015612.1\|WP_088028190.1\|136201_137368_+\|transglycosylase	unknown	unknown	gnl\|CDD\|225377
NZ_CP015612.1\|WP_088023160.1\|125175_126210_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223506
NZ_CP015612.1\|WP_088023156.1\|124376_125168_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NZ_CP015612.1\|WP_088023187.1\|141182_141752_+\|superoxide-dismutase-family-protein	unknown	unknown	gnl\|CDD\|376292
NZ_CP015612.1\|WP_088023175.1\|130609_131404_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088023180.1\|137855_138152_-\|HigA-family-addiction-module-antidote-protein	gnl\|CDD\|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	8.18529e-34
NZ_CP015612.1\|WP_088023169.1\|129082_129544_-\|META-domain-containing-protein	gnl\|CDD\|225728	COG3187, HslJ, Heat shock protein [Posttranslational modification, protein turnover, chaperones].	2.84185e-07
NZ_CP015612.1\|WP_088023163.1\|126266_128336_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	5.70785e-24
NZ_CP015612.1\|WP_088023184.1\|139640_141089_+\|nitrogen-regulation-protein-NR(I)	gnl\|CDD\|273818	TIGR01818, Nitrogen_assimilation_regulatory_protein, nitrogen regulation protein NR(I). This model represents NtrC, a DNA-binding response regulator that is phosphorylated by NtrB and interacts with sigma-54. NtrC usually controls the expression of glutamine synthase, GlnA, and may be called GlnL, GlnG, etc. [Central intermediary metabolism, Nitrogen metabolism, Regulatory functions, DNA interactions, Signal transduction, Two-component systems].	0
NZ_CP015612.1\|WP_088023189.1\|141783_142410_+\|superoxide-dismutase-family-protein	gnl\|CDD\|376292	pfam00080, Sod_Cu, Copper/zinc superoxide dismutase (SODC). superoxide dismutases (SODs) catalyze the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD1 gene cause familial amyotrophic lateral sclerosis (Lou Gehrig's disease). Structure is an eight-stranded beta sandwich, similar to the immunoglobulin fold.	3.95844e-52
NZ_CP015612.1\|WP_004134334.1\|133370_133709_+\|P-II-family-nitrogen-regulator	gnl\|CDD\|223424	COG0347, GlnK, Nitrogen regulatory protein PII [Amino acid transport and metabolism].	3.60313e-56
NZ_CP015612.1\|WP_088023182.1\|138165_138447_-\|excinuclease-ABC-subunit-A	gnl\|CDD\|226079	COG3549, HigB, Plasmid maintenance system killer protein [General function prediction only].	1.52273e-25
NZ_CP015612.1\|WP_088023176.1\|133730_135161_+\|ammonium-transporter	gnl\|CDD\|182630	PRK10666, PRK10666, ammonium transporter AmtB.	2.11265e-176
NZ_CP015612.1\|WP_014035517.1\|138586_139648_+\|two-component-sensor-histidine-kinase	gnl\|CDD\|226370	COG3852, NtrB, Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms].	3.60194e-111
NZ_CP015612.1\|WP_004153533.1\|131628_133038_+\|type-I-glutamate--ammonia-ligase	gnl\|CDD\|181884	PRK09469, glnA, glutamate--ammonia ligase.	0
NZ_CP015612.1\|WP_088023166.1\|128346_128958_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	2.30396e-51
NZ_CP015612.1\|WP_088023172.1\|129711_130536_-\|META-and-DUF4377-domain-containing-protein	gnl\|CDD\|379548	pfam14302, DUF4377, Domain of unknown function (DUF4377). This domain family is found in bacteria and archaea, and is approximately 80 amino acids in length.	1.05262e-26
NZ_CP015612.1\|WP_088023178.1\|135387_136134_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|225567	COG3023, ampD, N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	3.20729e-53
NZ_CP015612.1\|WP_088028190.1\|136201_137368_+\|transglycosylase	gnl\|CDD\|225377	COG2821, MltA, Membrane-bound lytic murein transglycosylase [Cell envelope biogenesis, outer membrane].	8.92145e-115
NZ_CP015612.1\|WP_088023160.1\|125175_126210_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|223506	COG0429, COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only].	1.23758e-29
NZ_CP015612.1\|WP_088023156.1\|124376_125168_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	6.0075e-38
NZ_CP015612.1\|WP_088023187.1\|141182_141752_+\|superoxide-dismutase-family-protein	gnl\|CDD\|376292	pfam00080, Sod_Cu, Copper/zinc superoxide dismutase (SODC). superoxide dismutases (SODs) catalyze the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD1 gene cause familial amyotrophic lateral sclerosis (Lou Gehrig's disease). Structure is an eight-stranded beta sandwich, similar to the immunoglobulin fold.	6.94877e-42
NZ_CP015612.1\|WP_088023175.1\|130609_131404_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	2.76673e-85

>NZ_CP015612.1|WP_088023176.1|133730_135161_+|ammonium-transporter
MKMRLLTGWQARFHLVCLLMLLSALAAGAWPGSAHAQVQVSPLPSESVAVEPLQDPAAAAAAPAVAEAAAAYDRGDVAWMLTSTLLVLLMVVPGLALFYGGLVRSKNVLSVLSQILVVFSLVLLLWVAYGYSAVFSAGNPFFGSFTEFAFLKGFTPDSVGNTPIKGLPDYLFVAFQSTFAGITTALIVGAFAERIKFRAVLLFSALWFTLSYIPMAHIVWGGGYLGEMGAIDFAGGTVVHINAGVAGLVAAWFVGKRLGYGQTALKPHNVPFTYIGAMLLWVGWFGFNAGSAAAADTVASLAFLNTVLATAAAVLGWTLVEAISKGKPSALGAASGAVAGLVGITPACGTVGPLGAIIIGFVAGVVCVWGVTGLKRLLKVDDTADVFGVHGVGGIVGAILTGVFSAQSLGGTKADLDIAHQVWVQVVSVGLTVVWSAVVTTLILLVVRSVVGLRVTEEAERTGLDVTSHGESAYEA
>NZ_CP015612.1|WP_004134334.1|133370_133709_+|P-II-family-nitrogen-regulator
MKLISAIIRPFKLDEVREALSDAGVSGITVTEVKGFGRQKGHTELYRGAEYVVDFLPKIKIETVVTDERADAVIEAIQSSAGTGKIGDGKIFVTAVEQVIRIRTGEIGADAL
>NZ_CP015612.1|WP_004153533.1|131628_133038_+|type-I-glutamate--ammonia-ligase
MSVENVEKLIKDNQIEFVDLRFVDMRGVEQHVTFPVSIVEPSLFEEGKMFDGSSIAGWKGIAESDMVLLPDTASAYVDPFYADPTIVISCDILDPATMQPYGRCPRGIAKRAEAYLKSSGIAETAFFGPEPEFFIFDSVRFANEMGHTFFQVDSEEAAWNSGAKYDGANSGYRPGVKGGYFPVPPTDTLHDLRAEMCKTLEQVGIEVEVQHHEVATAGQCEIGTKFSTLVQKADELLRMKYVIKNVAHRNGKTVTFMPKPIVGDNGSGMHVHQSLSKGGTNLFSGDGYGGLSQLALWYIGGIFKHAKAINAFANSGTNSYKRLVPGYEAPVMLAYSARNRSASCRIPWVSNPKARRIEMRFPDPIQSGYLTFTALMMAGLDGIKNQIDPGAPSDKDLYDLPPEEEKLIPQVCSSLDQALEALDKDREFLKAGGVMSDDFIDGYIALKMQEVTKFRAATHPLEYQLYYAS
>NZ_CP015612.1|WP_088023175.1|130609_131404_-|undecaprenyl-diphosphate-phosphatase
MSDLLSALLLGILEGLTEFLPISSTGHLLIAQHWLGARSDFFNIVIQAGAIVAVVLVFRQRLLQLATGFNQRGNREYVFKLGAAFLVTAVVGLVVRKAGWSLPETVSPVAWALIIGGVWMLLVEAYTARLPDRDQVTWTVAIGVGLAQVVAGVFPGTSRSASAIFLAMLLGLSRRAAAAEFVFLVGIPTMFAASAYTFLEMAKAGQLGSEDWTDVGVAFLAAAVTGFVVVKWLMGYIKSHRFTAFAIYRIALGAALLLWLPSGS
>NZ_CP015612.1|WP_088023172.1|129711_130536_-|META-and-DUF4377-domain-containing-protein
MNRKLTLLLPLALMAACSQTPAPAGTGGDDVAPAAAKAADQQTLAHLDAQRLQSQHWLLQQATAADGKRIDALFAREDKPVTLDFADGRLSVSNACNHMGGGYTLADGKLTVSAMASTMMACNDKALMALDEAVSSRLQGELKAEQDADGKLTLTTAKGDVLVFNPEPTAETRYGGAGETVFLEVAAKTEKCSHPLIPDYQCLQVREVKFDDKGLKQGEPGKFENFYGNIEGYTHEDGVRNVVRVKRYEVKNPPADAPSQAYVLDMVVESAIEK
>NZ_CP015612.1|WP_088023169.1|129082_129544_-|META-domain-containing-protein
MKHVPILIATALLAACIDASAASTPTTAQLEAHTWQLTRATDAQGRRIGELFVRDRPPYTLRFQPGYMSESNLCNNVSNEYQLLGNRLILRNGVQTTAQCIDQRMIVKQERAGSLVHGGDPAPTLELDDRGALVLRNAQGDTAVFEPAPLPVK
>NZ_CP015612.1|WP_088023166.1|128346_128958_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MQLSSNNLTNGAPIDREFAAGDAAGFAPDRNPHLAWSAAPAGTRSFLLVCVDPDVPTVPETVGRNDMTVPRDQPRCDFVHWVMADIPASVQEIAAGSCSDGFVVKGKPAPAGPAGSRQGLNDFTGWFAGNPDMAGDYLGYDGPYPPFNDERVHRYFFRVFALDVASLQLPARFTAADAYRAMHGHVLAEATLHGTYTLNPALG
>NZ_CP015612.1|WP_088023163.1|126266_128336_+|tetratricopeptide-repeat-protein
MQDQIIQALRQNQADQAVQLAQAWTRDEPGRADAHRWLALALQQQGNAEAAMEALQQALRLAPDDAQLHLQHAGLLLALRQFEGADEALVRTTGLDPNSFSAYLMQAHLAIGRNDFDEAQRISTLAARVEPEHPELLTIDGMVALRRGEADRALALLSAASKALPDDTRVLYALGFAYLGKDMLAFAEQSFRRVLELNPSMSSLHGLVVQLALRQGNVPAAAEAMQAALRQPELDVPAMRRLAGELALRNGQPLQALDYLLPLLETQPEDRQVLQLLLMSWQRLGREEEARARLDAVLDAHDQLHDVWLARLAIEQVGSESAVTAVERWMAAMPTHVPALEARLRLHDMAGEHAQAEAIAERIVSLEPGRVSGESRLVEGLLQRDPAAAVARVQALIEQAPEAHRADLRTWMGEIQDRAGQPQEALRTWMSLQTDQAPQRLPLPPQAKSPPSWPDKGSIEGDASSAPIFLWGAPGSGVERVATGLAAASPVLRSDRYTNTPPDDAFQNYNTLQDLASGVLTPERLVQRWREQLPARGLQSDTVIDWLLWWDNALLWALRPQLPQGRLVLVLRDPRDMLLDWVAYGAAAPLAMTSLAEASEWLTRALTQIATLHEDDLYPHVLLRIDQIGNDPHAMAELLGRLFERPMPPAAQLGAPRLPAGHWRNYRDVMSAAFAQLTPVAVRLGYPEE
>NZ_CP015612.1|WP_088023160.1|125175_126210_+|alpha/beta-fold-hydrolase
MALIPPPVLDAGTPTLHAADYQPPRWLRNPHLQSMLSSSRMRLQRGLLLLAATGAVSEELILDGGDGVRLQGWHSHVEGREPKGMALLLHGWEGSAESSYMRMAAARMLEQGFDVVRLNFRDHGNTHHLNPGIFHSNLIDEVVHAAGDIAQRWPQLPLVAAGYSLGGNFVLRLALRAPAAGVPLLRVASVCPVLDPALTMDSIENGPAMYDWYFRRKWAGSLRRKRDLFPELSDCDDRVLKLDIRALTAWLVERHTSFGSLQAYFDGYSIAGDRLSTLQVPADILMAQDDPVIPYATFSDWQLPRQAHLETACWGGHCGFIENWRGDGFSERWVAQRLQRVLQA
>NZ_CP015612.1|WP_088023156.1|124376_125168_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MTSPTPAPRGGVARVCRYLYRVPLLLVHITVFLPLILIGMLPPWGELRVGEATFGAKVVNWWQGGLMWIFGFRLVQIGKPLPGAVLFVANHVSWVDICILHSQRMMGFVAKREIASWPLVGWLAARGQTIFHQRGNTESLGGVMQVMADRLRGGRAVGVFPEGRTRGGHEVGPFHARIFQAAVETGVPVQPVALVYGVHGNAQTIVAFGPGESFFANFLRLLGEPARRAEVHFLAPIGAQDLEGRRRIAETSRARIVAAMSTQ
>NZ_CP015612.1|WP_088023178.1|135387_136134_+|N-acetylmuramoyl-L-alanine-amidase
MHPTRTALMLSACLLLAACASTPQETRNPLATWVPSPNQNARTPVIIVIHHTEQKSVQQSLRTLRTANSGGPVSAHYLIGADGHRYQLVADERRAWHAGAGRWGTITDLNSASIGIELDNDGRSPFSAAQIESLIVLLRDLTTRLNIPPRQVIGHADLAPTRKQDPSRFFPWQQLAEAGFGVWPRAADGAAPEGFDAWNALARFGYPLDNRDATVAAFHRRFRGRDDLPKTLDAEDARILHSLMLQTP
>NZ_CP015612.1|WP_088028190.1|136201_137368_+|transglycosylase
MIDSATSFKRRHWTLLAAAVLAGCSTTAPRTGSEAPTPVTPPAATYAKAAWSALPPVSDSDLQAGFVAWRSSCTRLKNDAVWAKPCATAATVADKDPAAIRQFLQRDLDVYALRAGGHQADGLITGYYEPIYPGSLTRTATATVPVYGTPDDLVVVQLDSLYPELKGKRLRGRVDGKVLKPYDDAGTIASKGAKAPVLAWLTDPMDLQLLQIQGSGRVRLGDGTQVRLAYAEQNGHPYRAIGRWLVDQGQLKKEDVTMDAIRAWARANPARVPELLRSNPSYVFFVRNPDSPEGPRGSLNVPLTAGYSVAVDRSVVPLGSLLWLSTTRPDGSPVVRPVAAQDTGGAIAGEVRADLYWGSGDAAGKLAGDMKQKGNIWMLWPKGVALPQ
>NZ_CP015612.1|WP_049435403.1|137477_137792_+|hypothetical-protein
MTYAKHNAKSGAKSAAKKYYKHWAESGLGKGNVLMEARGEKIVRQVEIYGTKMVWADEHAHSDDRFLLADQPVSFLDFDEDDEISAREFESAWKKAREATGYPV
>NZ_CP015612.1|WP_088023180.1|137855_138152_-|HigA-family-addiction-module-antidote-protein
MRTAPYPAPGEILLHEFLEPLGITQYRLAKAIGVSQRRIGEIVSGDRAVTADTGLRLSRYFGVSDKFWIGLQADFDAAMTKEKLADVLARIEPYNAAA
>NZ_CP015612.1|WP_088023182.1|138165_138447_-|excinuclease-ABC-subunit-A
MPIQSFACKRTQALFEGHRVQRWHHIEAAALRKLAMLNVAADLRDLRLPPANRLESLHGDRRGQYSIRINDQFRLCFVWSREGPAEVEIVDYH
>NZ_CP015612.1|WP_014035517.1|138586_139648_+|two-component-sensor-histidine-kinase
MSDPAPPPSLDALGTPLAWAGADGCIAGCNPAFARWLGVSARRLLGRPLAALEVQGEALAHFLARDERDSLRLNRLALAVPGEAPRFAEGWMSRRDDGGWLLEAHPVDEFPGLDPTQALPSALSAALKGLAHELRNPLAGLKGAAQLLARRAAQRDASERELIELIGSEIERLNGLLDQLLSPAPAAPHAELNIHAALERVLRLAENEAGWAVRLQRDYDPSIPEFHGDADRLTQAVWNLVRNAIQAGAGSITLRTRVEHGVRIAEQLHTLALRLEIADDGRGVPEELAEHLFLPLVSGRAEGTGLGLALAQQVAREHRGTLTYRSRPGHTVFTLLLPIISGAAPAEEAPRDV
>NZ_CP015612.1|WP_088023184.1|139640_141089_+|nitrogen-regulation-protein-NR(I)
MSESSSSPQRIWVVDDDRAVRFVLCTALREAGYQVVDFDSAASALQALSEGPPPALLFTDVRMPGDDGLVLLDKLKAALPQLPVVVMSAYTDVASTAGAFRGGAHEFLSKPFDLDDAVALAQRVLPAIAPALAAPTPAAEAPSDQPPQLVGDTPPMRALFRAIGRLAQAPLAVLITGETGTGKELVANALHRESPRAHGPFVALNTAAIPAELLESELFGHEAGAFTGAQRRHIGRFEQANGGTLFLDEIGDMPLPLQTRLLRVLAQGEFFRVGGRELIRVDVRVVAATHQDLEGLVAQGKFRADLLHRLDVVRLQLPPLRERREDIAQLASTFLAAAARKLDTPPKRLTAAALQALREHDWPGNVRELENVCWRMAALAAADTIGVADVDTALNRTRGRRSSTTGADPGQWEALLAEWARRQLAEGVEGLHAQVRERVDHALLEAALQITHGRRAEAAARLGLGRNTLTRKLGAGRRRGGH
>NZ_CP015612.1|WP_088023187.1|141182_141752_+|superoxide-dismutase-family-protein
MRLSFAILPLSAAVLLSACGSAPKKAEPTPPPPVAVSAAKQAEANLSPASASIVSGRIALMVEPGGIHITGLIGGLQPMQQAGFHIHERGDCSAVDASSAGNHFNPGGAAHGRAGTGKHHLGDMDNLRADAQGRANVDIHLKGVTLGGGAATDIAGRALVVHANADDYRSQPAGNAGVRIACGVIRVVR
>NZ_CP015612.1|WP_088023189.1|141783_142410_+|superoxide-dismutase-family-protein
MRLIHTSLFAAIAALGLAACNQQPAAPQAETPPAAPADGATTEPAATPAPAAAPAADASASAELAPTQGNETKGSVTFKVVDGKVHVTGQITGLKPGSEHGFHIHEKGDCSAPDGMSAGGHFNPGKQDHGNVATDPHHGGDMPNIKADDKGVATIDGPVSSNVNIGKGDDFDIIGRGLIVHADADDYKTQPTGNAGARLACAVIQKAP
>NZ_CP015612.1|WP_088023192.1|142657_143545_-|hypothetical-protein
MSKPDPAMNALGVLALELAGGEIPRQAVLSAEQAGELAERVGRDLSKLVPQVAELDLVFAAAHFDPAEVLRPGWPIHRRLEELQMRAPGRNQGPRLLAFGTDANGDVPLPFQADASLVGGGLRVVPFLLTGSDVATTNAVAEALEETLLANGMAHADTALMAQNTFGARIEHARYFTVNDLAAMMSMQYDNQGLAALWPLIETAIMAPGEDEWLNAAPEPLLRYTHGEARMALFDPAGWCAHYDHGKNDCDRLKGIYEQFLMRQRQMAAVLEAHGVPVLFVHCEAGQDARELLAR

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Crispr_ID: NZ_CP015612_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_2

486965-487072

Orphan

Consensus_repeat	Method
AGCTTCATCCACGCATGGCGTGGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_2

>merge|NZ_CP015612|2|486965-487072|CRISPRCasFinder
AGCTTCATCCACGCATGGCGTGGATCTACTGACACCATGATTCTGGTGGGTGCCAACCTTGGTTGGCACGCGTTGCGCGATAAAGCTTCATCCACGCATGGCGTGGAT

>NZ_CP015612|2|2|486965-487072|CRISPRCasFinder
AGCTTCATCCACGCATGGCGTGGAT	CTACTGACACCATGATTCTGGTGGGTGCCAACCTTGGTTGGCACGCGTTGCGCGATAA
AGCTTCATCCACGCATGGCGTGGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088023864.1\|477432_479082_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367655
NZ_CP015612.1\|WP_088023902.1\|500234_500777_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088023894.1\|495871_496753_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP015612.1\|WP_088023891.1\|492714_495777_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP015612.1\|WP_088023862.1\|476738_477416_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_012509930.1\|499895_500144_-\|DUF3297-family-protein	unknown	unknown	gnl\|CDD\|371696
NZ_CP015612.1\|WP_088023888.1\|490426_492538_-\|M13-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341056
NZ_CP015612.1\|WP_088023871.1\|483903_484674_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NZ_CP015612.1\|WP_006388655.1\|480166_480460_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP015612.1\|WP_088023899.1\|497291_498080_+\|dioxygenase	unknown	unknown	gnl\|CDD\|153375
NZ_CP015612.1\|WP_088023882.1\|487077_487665_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182632
NZ_CP015612.1\|WP_088023874.1\|484692_485037_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376986
NZ_CP015612.1\|WP_088023876.1\|485076_485691_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088023879.1\|486000_486930_+\|DUF2236-domain-containing-protein	unknown	unknown	gnl\|CDD\|226188
NZ_CP015612.1\|WP_032128751.1\|498197_499847_+\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|129911
NZ_CP015612.1\|WP_088023866.1\|480719_482369_+\|M28-family-peptidase	unknown	unknown	gnl\|CDD\|349910
NZ_CP015612.1\|WP_088023848.1\|479309_480170_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP015612.1\|WP_088023885.1\|487798_489013_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP015612.1\|WP_088023868.1\|482654_483914_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_CP015612.1\|WP_088023896.1\|496849_497260_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088023864.1\|477432_479082_+\|hypothetical-protein	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	1.32464e-06
NZ_CP015612.1\|WP_088023894.1\|495871_496753_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.91633e-93
NZ_CP015612.1\|WP_088023891.1\|492714_495777_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	9.53064e-94
NZ_CP015612.1\|WP_088023888.1\|490426_492538_-\|M13-family-metallopeptidase	gnl\|CDD\|341056	cd08662, M13, Peptidase family M13 includes neprilysin and endothelin-converting enzyme I. The M13 family of metallopeptidases includes neprilysin (neutral endopeptidase, NEP, enkephalinase, CD10, CALLA, EC 3.4.24.11), endothelin-converting enzyme I (ECE-1, EC 3.4.24.71), erythrocyte surface antigen KELL (ECE-3), phosphate-regulating gene on the X chromosome (PHEX), soluble secreted endopeptidase (SEP), and damage-induced neuronal endopeptidase (DINE)/X-converting enzyme (XCE). Proteins in this family fulfill a broad range of physiological roles due to the greater variation in the active site's S2' subsite allowing substrate specificity. NEP is expressed in a variety of tissues including kidney and brain, and is involved in many physiological and pathological processes, including blood pressure and inflammatory response. It degrades a wide array of substrates such as substance P, enkephalins, cholecystokinin, neurotensin and somatostatin. It is an important enzyme in the regulation of amyloid-beta (Abeta) protein that forms amyloid plaques that are associated with Alzeimers disease (AD). ECE-1 catalyzes the final rate-limiting step in the biosynthesis of endothelins via post-translational conversion of the biologically inactive big endothelins. Like NEP, it also hydrolyzes bradykinin, substance P, neurotensin, and Abeta. Endothelin-1 overproduction has been implicated in various diseases including stroke, asthma, hypertension, and cardiac and renal failure. Kell is a homolog of NEP and constitutes a major antigen on human erythrocytes; it preferentially cleaves big endothelin-3 to produce bioactive endothelin-3, but is also known to cleave substance P and neurokinin A. PHEX forms a complex interaction with fibroblast growth factor 23 (FGF23) and matrix extracellular phosphoglycoprotein, causing bone mineralization. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets; X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic rickets. ECEL1 is a brain metalloprotease which plays a critical role in the nervous regulation of the respiratory system, while DINE is abundantly expressed in the hypothalamus and its expression responds to nerve injury. A majority of these M13 proteases are prime therapeutic targets for selective inhibition.	0
NZ_CP015612.1\|WP_012509930.1\|499895_500144_-\|DUF3297-family-protein	gnl\|CDD\|371696	pfam11730, DUF3297, Protein of unknown function (DUF3297). This family is expressed in Proteobacteria and Actinobacteria. The function is not known.	1.00709e-44
NZ_CP015612.1\|WP_088023871.1\|483903_484674_+\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	3.15853e-51
NZ_CP015612.1\|WP_006388655.1\|480166_480460_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	5.76383e-05
NZ_CP015612.1\|WP_088023899.1\|497291_498080_+\|dioxygenase	gnl\|CDD\|153375	cd07363, 45_DOPA_Dioxygenase, The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine. This subfamily is composed of plant 4,5-DOPA Dioxygenase, the uncharacterized Escherichia coli protein Jw3007, and similar proteins. 4,5-DOPA Dioxygenase catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine (4,5-DOPA). The reaction results in the opening of the cyclic ring between carbons 4 and 5 and producing an unstable seco-DOPA that rearranges to betalamic acid. 4,5-DOPA Dioxygenase is a key enzyme in the biosynthetic pathway of the plant pigment betalain. Homologs of DODA are present not only in betalain-producing plants but also in bacteria and archaea. This enzyme is a member of the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon.	1.65797e-121
NZ_CP015612.1\|WP_088023882.1\|487077_487665_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|182632	PRK10668, PRK10668, DNA-binding transcriptional repressor AcrR; Provisional.	2.79744e-14
NZ_CP015612.1\|WP_088023874.1\|484692_485037_+\|hypothetical-protein	gnl\|CDD\|376986	pfam03090, Replicase, Replicase family. This is a family of bacterial plasmid DNA replication initiator proteins. pfam01051 is a similar family. These RepA proteins exist as monomers and dimers in equilibrium: monomers bind directly to repeated DNA sequences and thus activate replication; dimers repress repA transcription by binding an inversely repeated DNA operator. Dimer dissociation can occur spontaneously or be mediated by Hsp70 chaperones.	0.00476435
NZ_CP015612.1\|WP_088023879.1\|486000_486930_+\|DUF2236-domain-containing-protein	gnl\|CDD\|226188	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown].	2.34134e-58
NZ_CP015612.1\|WP_032128751.1\|498197_499847_+\|Na+/H+-antiporter	gnl\|CDD\|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	2.771e-102
NZ_CP015612.1\|WP_088023866.1\|480719_482369_+\|M28-family-peptidase	gnl\|CDD\|349910	cd05660, M28_like_PA, M28 Zn-peptidase containing a protease-associated (PA) domain insert. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. This subfamily is composed of uncharacterized proteins containing a protease-associated (PA) domain insert which may participate in substrate binding and/or promote conformational changes, influencing the stability and accessibility of the site to substrate.	6.29524e-106
NZ_CP015612.1\|WP_088023848.1\|479309_480170_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.43468e-55
NZ_CP015612.1\|WP_088023885.1\|487798_489013_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.68652e-20
NZ_CP015612.1\|WP_088023868.1\|482654_483914_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	1.78936e-43
NZ_CP015612.1\|WP_088023896.1\|496849_497260_+\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	4.49378e-10

>NZ_CP015612.1|WP_088023879.1|486000_486930_+|DUF2236-domain-containing-protein
MPALLQRLSRPVTAPIRRWVLEAFPRGQSGIDYDHPLGDPGWFGPDSVTWRLHAEFPSMLAGGLCALMLQTLHPRALAGVYDHSNFRQDLVGRLRRTTAFVAGTSYAPASEVETLVAKVRRIHAQIRGQTAQGETYAADDPQLLTWVHVTEAFGFLQGFRRYGREVPEHIADRYYDEYRCVAEALGAVDVPRSEAEVAAYFCARQPELRVDERSREVLEVLSGVRLPVPVPGLSREVFLGAGAALLPDWAEGMLERNARQRAQAAASAKLMQGMAPLFRRALPDGLASRACTRMGVQVEVLREWPELLR
>NZ_CP015612.1|WP_088023876.1|485076_485691_-|hypothetical-protein
MIALFKGLGLLLRDNELYSSPFDKQVAHWRNLSEQQIRDEVAVLAQAKCQWLIASIVGWQAASLLILGLITNYLWRDDYHITFTRVVVVFGSWISILFVIWFMANMFDRTAGFERWMKAFNSRARISSKADSVEHVAEALELAEHYPEVLDYKQAVTARRELRHEDIRIMTEIGRMKQHSELVGRLNHVGENEHHHDLTLQPAY
>NZ_CP015612.1|WP_088023874.1|484692_485037_+|hypothetical-protein
MRLFLLACIAALSLAGCDTSSNTSITRTRANGVDTLYSKGTVADGEARFQCIASSSGHCHYLVLDPACSTDAACAKPSLRRFAVAVGQTEAMRDLPKGFRQCVSQEPIEQCHRE
>NZ_CP015612.1|WP_088023871.1|483903_484674_+|response-regulator-transcription-factor
MPLEALIAEDEELLRQSLVQQLGRLWPDLRLVAECEDGASALEQLAEKQPDIAFLDIRMPGISGIEVARSLSELSPRTQVVFVTAYDQYAIDAFEQGAMDYLLKPVSDERLLATRERILSRLPSTRQDDAVLERLLQRLGPSQGAAERPPLAWITASNGRETQLIMLEDVAYFRADNKYTTVVTAAGESLLRTPLRELLEVLDPQHFRQIHRSTIVNMKAVAAVSRDDTGRGVLRLRGRAETLVVSQPFMSLFRGM
>NZ_CP015612.1|WP_088023868.1|482654_483914_+|sensor-histidine-kinase
MIASLSLILRHLLAWAAALFVAGMVWSGIFSGMNDGPGWVFGLLVMFLMISALGSAVTHVRRVWLVAGRLDGATLSGRQRRQIELPMDAGHAFAVVEAAVGELPRVEEVESSAGSLQVRAYVRRVDLWNGRQPSRWNLPARLAIKRNSVLATVTPGQGTSTVTLLFEPDAGWWADLLALDEGSNYENAEAVTRAISRRVADQRRDEQAAAEQTQVEKELSVARLNLLHAQVEPHFLYNTLANAQVLTRTDPARAEQMLGHLIQYLRSSLPQVDESVSTLGVELERTRAYLEILRIRMGARLAVEVQVPNELHGVHLPAMALQTLVENAIKHGLEPKPGGGTIWILARGFDDHVTVTVADDGLGFGQGTSGTGIGLKNLRERLRLTCGEQAGVAIVANFPSGVAATMTLPQSHKERSHAA
>NZ_CP015612.1|WP_088023866.1|480719_482369_+|M28-family-peptidase
MKRVVLGVLALSVSSALMAATPKFDGARISADVKELASDAYEGRSPATAGEEKTIAYLSKQFADAGLQPGGDLKDGKRLWTQAVPLRKGDIVGAPQLALHQGGKTVALEQGKQIAVRAAMNGASNVDISKAPLVFLGYGVKAPERNWDDFKGVDLKGKIAVVLINDPDFETGQGDFDGKGMTYYGRWTYKYEEGARQGALGVLIVHETAPASYGWATVAGSNTNTMFDVVRDNPADSHPLLEGWIQRDLAVELFRSAGQDFEALKKKAQQRDFTPVPLTGASLDAKYAVKTEVITSHNVAARLEGSRHPDETIIYSAHWDHIGVGEPDARGDRIFNGALDNASGTASLIELARGFAKEKRPQRSVVFLAVTAEEKGLLGSEYYATHPLYPLEKTVAVINMDGMAPFGPSRDFGIYGAARFELLDQLKDVAKGWDIRYTPDPKPEAGLFFRSDHFPFAKRGVPALSWSAGQDWVDGGVAAGKKASEDYTAKRYHQQGDEWQPDWVFAGAARDLEVLYTLGNQLANSRSWPNWSKDESFRAVRDASADQRK
>NZ_CP015612.1|WP_006388655.1|480166_480460_-|transposase
MSRITRRSYTDEFKHQAVELAESLGPAAAARQLEMSVKTLANWLDAVRAGRSLTSEARRPATDLESEISRLRAENANLKMEREILKKAAAFFARESK
>NZ_CP015612.1|WP_088023848.1|479309_480170_-|IS3-family-transposase
MRYAFVASQRTHYPTRLLCRVLGVSVSGFHDYLRRQCAQTCDVDSALRTELRAIHVTSKRSYGRRRLVRALRARNHPVGHKRVARLMAEERIQGKTKGRFRPKSSGGSSQLAPNLLDRQFAPGTGPTAWVGDITYVPTRQGWLHLAVVISVQTRQVLGYSVSKRLTEELVVKAFANAWALHPQRPGLIFHSDRGGQYWGNQFRQLLQSHEVVQSMSRPGNCWDNAVAESFFATLKTEEAAEPYASREQASQSIAAYIHGFYNPARLHSALGYHSPNNYARQLRAAA
>NZ_CP015612.1|WP_088023864.1|477432_479082_+|hypothetical-protein
MRMTYRLIGLGLAATLLAACGKQDTPAEAPAPAKDKATSALASNAPVEAAPLRGTPDFGGTTQVAREADGIGSTPELAVLAALQSAVAQVNGVRVASQMQSLRAGLHVDVDDEHVGDIRADAFTQQMIAGSQGAVLGYEILSQDEVRQLDEETIARVRASDEGWSFKGSASASASGEASAKGGSASASVKQSYDEKVSVDAKRGASSFDSDVTHRSMRSYWKVRVRAQIAQYRAPDEQGKPKIVVALPRTKAGSYAVGDGRVDADEVADAIRARLSDTLTQTQRFIVLDREFGDELQAEIDHINSGNVRLQDTARVGQQLATDLILIPTIERFEYPRSVRNLRMSDRQVTSYSGGGRITLRLINATTGQVVMSDSFDHQLASTGPSTLPRVVNGRNMAAAMMESLSGQIGTTIVTTLFPVSVVSVDGDQVVLSQGGDTVQAGQRWQAVRLGEELKDPQTGRSLGRSEHPCCTIRIDRVAAQTSYGTIEDGVDAMRGGFRPGQIELRQKLGSKPAAAASATASAAPAAAARPAAKPKPKPAAAPAEDPNW
>NZ_CP015612.1|WP_088023862.1|476738_477416_+|hypothetical-protein
MIRSTALTLAIAAATLSMPAHAGLGKLKDLAGAATGTSSSSASSAAAPDEAAQEALVRRFVTSQSHSLQAQTSFARAFGLAEQVQLLEAERQALSSGSVSVDAMKKSVSVSEAAQAAINERQAAQPELNAESKQHYAEGLVSLLSSAAEAQKLGGEASNFTAGMKNLGATQLATVGRKLAAGAWVAKESPGFIQGLYGSTKSAVTFAKKSKVKVPSNADSMLDKL
>NZ_CP015612.1|WP_088023882.1|487077_487665_-|TetR/AcrR-family-transcriptional-regulator
MVRRTRAEMEETRATLLATARRVFSEHGYAATSMDDLTAQAGLTRGALYHHFGDKKGLLAAVVAQLDAETDQRLQAISDTAEDAWEGFVQRCRAYLEMALEPEIQRIVLRDARAVLGGASPESQRHCVHSMQQLIEQLIAQGVVAAVDAQALASLIYGSLAEAAFWIAEGEDGDARLRQATAALEMLLRGLKSTG
>NZ_CP015612.1|WP_088023885.1|487798_489013_+|MFS-transporter
MATPYRDLFAAPGTAGLALAGLLARLPLPMTGIGIITLLSQLRGSYALAGAVSATFVLTYALLSPQVSRWVDRRGQGRVLPWATAASAAGLLLLLACTLLAAPDWTLFIAAMLAGCMPSVSAMVRARWTAIHRGRPQLQTAYSLETVFDEVTFIAGPPLSVGLSVAVWPQAGVLAATLLLVLGVTALVLQRGTEPPLQRCEGVTPSRSLLRQPEIRLLALLMLAMGVIVGTVDITSVAFAEQRGQPLAASWVLSAYALGSCAAGLLFGALKLRAPLQRLLLLGAAATALTTLPLLWVGSLPALAVAVLVAGLFFAPTMIVAMSLVEQRVPESRLTEGMTWLLAGLNIGVALGAALSGQSVDAGGVRSGFVVALVAGGGVLLFAVLAQRALRPSASTTSPEGIIP
>NZ_CP015612.1|WP_088023888.1|490426_492538_-|M13-family-metallopeptidase
MSKLRRPTLALAIVASLSLAACDRPAEPAAGTAAPADAAPAAAKPMLGSFGFDASGMDRSIAAGDDFFGFANGTWVKNTEIPADRSRFGSFNVIAEKTLADTRAILEGAAGNTQASGDDKLIGDYYAAYMDEAGIEQHGIAPVQPQLKAIEAITDKAGLARTLGGEMRADVDLLNATNFYTDRLFGLWVSVDMLQPDRTAPYLVQGGLGMPDRDFYLGGGRMAELRKQYQAYIAQMLQLAGVADPAGKAQRILALETKIAQAHATQEETNDVTKGANPWTQADFNAKAPGMDWSAFLDAAALGKQQDFIVWQPKAVAGLSRLVATEPLEVWKDYLAFHALDRAAAYLPKKFADARFAFHGTALSGTPQQSDRWKRAVDDANHAVGEAIGKRYVEKHFDAKTKERADEMAKNIIAAFAKRIDALSWMSPQTKAHAKAKVAGLTVGMGYPEKWRDYAGLEIRRDDALGNAQRAELFEYQRNIAKLGKPVDHSEWAMLPQTINAMNVPLENRLVFPAAILQPPFFDGAADDAVNYGAIGAVIGHEISHGFDNAGALFDETGKLHNWWTAEDLKQFNAAGDALAAQFSSYEPFPGVHVNGKLTLGENIADVAGLGTAYDAYQLSLQGKPGQTLEGFTPDQRFFLGFAQAWRSKSREQALRNSLLTDVHAPGQFRALTVRNIDAWYPAFEVKEGQKLYLAPDKRVKVW
>NZ_CP015612.1|WP_088023891.1|492714_495777_+|EAL-domain-containing-protein
MRGRVRRQEWRPPAVEVGDVEDSFAHEASRQHKEAQPMPALKRALARPLRAITWGGVLLGVLLVAGLATMLINDHQRRLEAAQRQSRALAVGSERLLALELRNLERAMSGIAADAAELFRSVPAQAPALLDASIDGVLRRHAELHSIVVLDRHGRSITAGKGDLNLPLWTDPQRRGQGSALYIGPPQRASDDGWVVPLALPMTGDRWLLARLRCGELQRIIGGLDVGPNGLVSISDAEGYMLARVPDPHGTVGRRYGLPRRDLLGKQAVVELGSLPGAVDGVPRIITISTLERSPLAVQVGLANEDVLAPWWPYLQASVAIVLAYTVVLLVLLYAVRRSTRRQQSMAEELKAGHAELRLAHQVGRICTWYVDEDAALLRWSPLAREIFGVQTDALPVADFFARVHRDDAARLQQAFDQAFAGGAVLDEVFRLVLPGGQVRWVGARGQRVEVADSERRMIGALSDLTERYQAREQMSEVERRFRLLFDRNPAPFWVFDPDTLRFIEVNDAAVRQYGYSREEFLAMSILDIRPREGWDEVKGAIAKARVGELQDATVRLHRRKDGSVFEVRAHLSRLDFDGQPACLVLAEDVSERLAYERDLAYQARHNPATGLLNVRALTEQLDEQDEGYTIAFVQLRGLQLVADTLGREIGDAVLQSMATRLGGLGARCGTLAFQPAEDFVFAIGAEHDTQRVLDDLLQIVSAPMRGKDSLHQFEPRIGVAVHVPGDGHSAEQVIGMAAQAAHAARAEGNVVVWFDAAVTTRLADRLRLAGRIHAAIDNEFQLYFQPIRHASDGSPAALEALLRWPQADGSFIPPNEFIQLCEDTGLILALGRWVIRAAAKAQRRLVEAGWGELPIAVNVSAVQFFNSDLVAEFTRAQQEFGLARGALHVELTESSLMRKPGQAMQTMQRLHEQGISVSLDDFGTGYSSMSYLQHLPLDILKIDRSFVADVETNPRNASICRALLSLGHSMGLTIIAEGVETPGQLDWLAAHGCDQVQGYLLGRPAPLERIIDALDEVAA
>NZ_CP015612.1|WP_088023894.1|495871_496753_-|LysR-family-transcriptional-regulator
MDTLEAMRVFVAVVERNGFSAAAQALDMSTAGVTRQVAALEKRLSTRLLHRTTRRVSPTSTGAAYYAQCVRLLAEFDALEASIGAQALEPSGTLRINAPVSWGIARLGPLLASYRERFPQVELDLALSDRLVDMVEEGYDVAIRITREPGPTLIARRLGESRVSLCAAPAYLAARGTPQTPQELQAHACLSYSYWAAGNNWPLQGPGREVKVAVNSLLHANNGDVLREAAIAGMGVILQPDFLLEDALADGRLVRVLPEWEAAPIGIFAVYTSRSHLAPKVRSFIDHLVETGV
>NZ_CP015612.1|WP_088023896.1|496849_497260_+|DoxX-family-protein
MHTTTAPVSPLAPYGATLLRLALGVLFLAHALTKLLVFTPAGTAAYFESLGLPGVLGYLTIGVELVITAALLLGIYARWVGLVGVPLLLGTIVTVHGANGFGFANAGGGWEYPAFWALALVVLFLVGDGKWTLRSR
>NZ_CP015612.1|WP_088023899.1|497291_498080_+|dioxygenase
MSRLPSLYISHGSPMTALHPGQVGVRLAELARDLPTPRAIVMASAHWLGRQPLVGAHPQPPTIHDFGGFPRALFELQYPAPGDPALAEEVAGRIAAAGLPVALDPQRGLDHGAWVPLGLLRPQADIPVVPVSIQPLLGPEHQFALGRALAPLRDQGVLLVGSGSITHNLHDWGDYQDGKEAPYVRPFIEWVEQRLAADDRQALLDYRRQAPFAERAHPTDEHLLPLFFAMGAAGEGGFGARRIDAGIDAGFLAMDLYRFDGA
>NZ_CP015612.1|WP_032128751.1|498197_499847_+|Na+/H+-antiporter
MHTIEVVLAMLVAVVASGYLVRVLPFSLPLPLVQIGLGAVIAGVFNRGHALEPEVFFLLFLPPLLFLDGWRIPKQGLFRDKGAILELAFGLVVFTVIGAGFLIHWLIPVMPLAVCFALAAIVSPTDPVAVGAIASKAPIPKRLMHILEGESLLNDASGLVCFRFAVAAVMTGTFSLATASLTFVWVAVAGLAVGVAVTLGVSTFQRWLWRRFGEEPGAAMLVNLLIPFAAYLLAEEIHASGILAAVAAGIAMSYVELTGRVSGSMRVQRAGVWNMLQFSFNGIMFVLLGEQLPGIVERATTTMNETGHQSAWWLLVYVVVINLALVVLRLLWVWLSLRWNLLRARRRGLERGEAPNWRIVVATSVAGVRGAITLAGVLTLPLFLPDGSAFPARDLVIFLAASVILFSLLGASIALPRLLKGLQLPSDSGERKEEDLARRLSSKAALAGVERMRQQMVMNQNTENVQLYNDAASRVSLLYQRHLEKDSDGPDVDPEKVRRMELGYRQLRSAGLNAEREELFRLTRRGVISDEISRRLIRNLDLLESRKRE
>NZ_CP015612.1|WP_012509930.1|499895_500144_-|DUF3297-family-protein
MSDTPPDHLAINPASPFHDAQALERGVGVRFNDVERDNVEEYSVSEGWIRVQAGKARDRRGNPMTIKVKGKVEAYFLETKPE
>NZ_CP015612.1|WP_088023902.1|500234_500777_+|hypothetical-protein
MPDNSDYFDFEEDIHDFDEEGFEARVWNLLVLINPGDEELALQQFNRWREHLAEDGQPLEADSDWLPALFTAIAWQSGFEVERDDLESLQSAVNELSARFNLQLDWGGDLDDEDFAEDLDGVQLMSTAFDRLREHNYTLWSVDAGSDGFTGVMALTRDDDAMLALCSLLDVEIRLGSDPF

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Crispr_ID: NZ_CP015612_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_3

758411-758498

Orphan

Consensus_repeat	Method
GGTAGGTGCCGAGCTTGCTCGGCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_3

>merge|NZ_CP015612|3|758411-758498|CRISPRCasFinder
GGTAGGTGCCGAGCTTGCTCGGCACGCTCTTTCCCGCATCCACGCGTGGCGTGGATCTACCGGTAGGTGCCGAGCCTGCTCGGCACGC

>NZ_CP015612|3|3|758411-758498|CRISPRCasFinder
GGTAGGTGCCGAGCTTGCTCGGCACGC	TCTTTCCCGCATCCACGCGTGGCGTGGATCTACC
GGTAGGTGCCGAGCCTGCTCGGCACGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088028233.1\|748723_749719_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NZ_CP015612.1\|WP_005408127.1\|766340_767090_+\|TerC-family-protein	unknown	unknown	gnl\|CDD\|223930
NZ_CP015612.1\|WP_088024361.1\|747722_748550_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|181382
NZ_CP015612.1\|WP_088028237.1\|754539_756747_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273808
NZ_CP015612.1\|WP_088024377.1\|758517_761034_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|225669
NZ_CP015612.1\|WP_086016257.1\|762452_763199_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP015612.1\|WP_010481870.1\|751438_752737_-\|nucleoside-transporter-NupC	unknown	unknown	gnl\|CDD\|224883
NZ_CP015612.1\|WP_088024391.1\|769028_769649_+\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP015612.1\|WP_088024371.1\|756751_757351_+\|Hemin-transport-protein	unknown	unknown	gnl\|CDD\|226243
NZ_CP015612.1\|WP_088024363.1\|749866_750298_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088024374.1\|757422_758349_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088028235.1\|752930_753902_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381369
NZ_CP015612.1\|WP_088024385.1\|764997_765699_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239946
NZ_CP015612.1\|WP_088024366.1\|750447_751413_-\|ribokinase	unknown	unknown	gnl\|CDD\|238579
NZ_CP015612.1\|WP_088024383.1\|763356_764628_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP015612.1\|WP_004144386.1\|761753_762398_+\|arylesterase	unknown	unknown	gnl\|CDD\|238860
NZ_CP015612.1\|WP_088024388.1\|767337_768498_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP015612.1\|WP_005412278.1\|754155_754350_+\|hemin-uptake-protein-HemP	unknown	unknown	gnl\|CDD\|378463
NZ_CP015612.1\|WP_049435654.1\|765912_766308_+\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|260133
NZ_CP015612.1\|WP_088024380.1\|761030_761678_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226647

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088028233.1\|748723_749719_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	1.72517e-146
NZ_CP015612.1\|WP_005408127.1\|766340_767090_+\|TerC-family-protein	gnl\|CDD\|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	5.3089e-69
NZ_CP015612.1\|WP_088024361.1\|747722_748550_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|181382	PRK08317, PRK08317, hypothetical protein; Provisional.	4.54998e-27
NZ_CP015612.1\|WP_088028237.1\|754539_756747_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273808	TIGR01786, hemoglobin-haptoglobin-binding_protein, TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein. This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	3.78842e-125
NZ_CP015612.1\|WP_088024377.1\|758517_761034_-\|FtsX-like-permease-family-protein	gnl\|CDD\|225669	COG3127, COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	6.75995e-180
NZ_CP015612.1\|WP_086016257.1\|762452_763199_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.31743e-76
NZ_CP015612.1\|WP_088024391.1\|769028_769649_+\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	8.00536e-79
NZ_CP015612.1\|WP_088024371.1\|756751_757351_+\|Hemin-transport-protein	gnl\|CDD\|226243	COG3720, HemS, Putative heme degradation protein [Inorganic ion transport and metabolism].	0.00226125
NZ_CP015612.1\|WP_088024366.1\|750447_751413_-\|ribokinase	gnl\|CDD\|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	2.48293e-99
NZ_CP015612.1\|WP_010481870.1\|751438_752737_-\|nucleoside-transporter-NupC	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	6.59038e-143
NZ_CP015612.1\|WP_088028235.1\|752930_753902_+\|aldo/keto-reductase	gnl\|CDD\|381369	cd19143, AKR_AKR6C1_2, AKR6C family of aldo-keto reductase (AKR). Voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa are founding members of aldo-keto reductase family 6 member C1 (AKR6C1) and C2 (AKR6C2), respectively. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	0
NZ_CP015612.1\|WP_088024385.1\|764997_765699_-\|hypothetical-protein	gnl\|CDD\|239946	cd04502, SGNH_hydrolase_like_7, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	2.18193e-78
NZ_CP015612.1\|WP_088024383.1\|763356_764628_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.198e-48
NZ_CP015612.1\|WP_004144386.1\|761753_762398_+\|arylesterase	gnl\|CDD\|238860	cd01822, Lysophospholipase_L1_like, Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity.	5.01537e-86
NZ_CP015612.1\|WP_088024388.1\|767337_768498_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.48436e-81
NZ_CP015612.1\|WP_005412278.1\|754155_754350_+\|hemin-uptake-protein-HemP	gnl\|CDD\|378463	pfam10636, hemP, Hemin uptake protein hemP. This is a bacterial family of proteins that are involved in the uptake of the iron source hemin.	2.47066e-16
NZ_CP015612.1\|WP_049435654.1\|765912_766308_+\|diacylglycerol-kinase	gnl\|CDD\|260133	cd14264, DAGK_IM, Integral membrane diacylglycerol kinase. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of diacylglycerol to phosphatidic acid. Escherichia coli DAGK participates in the membrane-derived oligosaccharide cycle (MDO cycle) by recycling lipids to restore phosphatidylglycerols that were used up in the biosynthesis of MDOs. DAGK also recycles diacylglycerols that are produced during the biosynthesis of lipopolysaccharides (LPS) back to phospholipids. DAGK is not the main source of phosphatidic acid in de-novo biosynthesis of glycerophospholipids. Escherichia coli DAGK has low activity as an undecaprenol kinase.	2.33259e-49
NZ_CP015612.1\|WP_088024380.1\|761030_761678_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226647	COG4181, COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism].	5.28335e-96

>NZ_CP015612.1|WP_088024374.1|757422_758349_+|hypothetical-protein
MKLQTASAMLLLAASGVASAQPSDIARDHDSILAMQGEYTVDFAFDETVLLKPGYERAPAMRSGGSEVVIVVEDTPKRIVLQHLLLDEKSGHITKHWRQDWVYEAPNRFEFSADQTWKVRSIPEAVNQGAWTQCVYEVSDAPRYCGTGTWTYTNNVPSWTSDLSWRPLPRREYTKRSDYNALAVVNRHTLTPNGWTHEQFNTKVQRNADGSQVEIAREFGFNDYVKTTEVDFTPARDYWKATAGYWARVRQRWDGFLGQAPGVHLKTKIDGMAMIIPMFTQAEEIQAGKKVKDKQIDDVFAKYVEKAL
>NZ_CP015612.1|WP_088024371.1|756751_757351_+|Hemin-transport-protein
MSRALSARRNDSIAAPHSAAWPTPAQLATLGTVLCLYHADGNELGGWRQAVRVHACQGVDSEGLRESLCFLDGRGRCVWRLYLLPDSDFLAWDRLVAALPPGPEHDSDGSVGERLWRRLAGHLGGQRWRLCALRLHAADDGRTLAASLSTLSSLGAVTARRIARLENAEGELAIDDCCCADAARHPAPRIPGDLPLIRL
>NZ_CP015612.1|WP_088028237.1|754539_756747_+|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MALPLSAHAAAAAAPDAREFDRVQVTATRTERAVSDVAATVDVIDREQMDRHLVQDIKDLVRYEPGLSVTRSATRFGLDGFRIRGLDGNRVRIQTDGIVMPTRFDIGSFASSNRNFTDLDTLKRVEIVRGPASSLYGSDALGGVVAFVTKDPADYLKDGKNSYFGLKFGYDGEWKGLLGGATAAFGGDHWSGLVNVNHHQGQETDNKGTVRSDNDTRTASNPQDRDGRSLLSKLVYAPSEDQRFRLTVEGNEDTTDTNVLSAIASIAPPPGALAAATGMKSHDTQKRTRVSFAHEMDALDQPFADSLHWQVYAQNSETRQQTDETRTDGSRRHRVFSFDQHAFGLQAQFNKAFSTGAVEHALTYGFEGTRTEIRQKRDGYQVNRAGVVSNTVTPDTFPVRDFPISKTTELGLYAQDEMRLADGKLSLVPGVRVDRYELKPEVDSIFAEDNPTTAVAQLKKTSVSPKLGMVWRFTDQWSLFAGYARGFRSPPYNDVNIGLTNVAFRYTAIANPDLKPETSDGYELGLRFIAPAAYVSVSGYYNDYKDFIESNVDTGRNAQGLTVFQSQNIADARIYGAEMKAGIEFGELSPALKGWALRSALAWSRGDNRTDDEPLASVDPLRGTLGLMYDTDSWGVELAGTFVQRKKRLPPPAAQTNPNAPAPFVYQPAGYGVLDLMAHWNFAPGATFNVGVFNLADKRYIEWSSITPSLITNRALSDRYSSPGRTFSASLAVSW
>NZ_CP015612.1|WP_005412278.1|754155_754350_+|hemin-uptake-protein-HemP
MNAQPVLLRPETLTLRDRPVRVVPPEEVIDSEALLKGRREILIQHGDRFYRLRHTSNDKLILTK
>NZ_CP015612.1|WP_088028235.1|752930_753902_+|aldo/keto-reductase
MQYRRLGSTGLPISALSFGAWVTFGDQIPRDEARNLVAAAWDHGVNFFDNAEGYANGRAEQVMGDVITDLRLPRDGFCVSSKVFFGSAKDPRPTQRGLSRKHVTDACHAALKRLRVDYLDLYYCHRPDPDAPIAETVHAMDTLVRQGKILYWGTSEWSAAQIQQALDIAEARNLQGPSMEQPQYNLLHRERVEVEYAPLYAGAGLGTTIFSPLASGLLTGKYDQGIPADARLGREGMEWLQDLVLGAEAEARLGQVRRFSEVARALGQAPATLAIAWCLRNPNVSSVILGASRVSQLLQNLQALDVLEQVDAAGWAQVEAVFG
>NZ_CP015612.1|WP_010481870.1|751438_752737_-|nucleoside-transporter-NupC
MVEGLGRIGFGLFGLAVLIGITWLFSNNKRAVDWKLVATGITLQIAFAALVILVPGGRDVFDALGKGFVKILSYVNEGSGFIFGSLMDTKNYGFIFAFQVLPTIIFFSALMGVMYHLNIMQGIVRVMAWSITKVMRVSGAETTSVCASVFIGQTEAPLTVRPYIARMTQSELLTMMIGGMAHIAGGVLAAYVGMLGGGDPAQQAFYAKHLLAASIMAAPATLVVAKLLIPETGTPLTRGTVKMEVEKTSSNIIDAAAAGAGDGLKLALNIGAMLLAFIALIALLNAPLTWIGDVTGLAAAIGKPTNLSTIFGYVLAPIAWVIGTPWADATTVGSLIGQKVVINEFVAYTELSQIVNGQIAGVSLSEEGRLIATYALCGFANFSSIAIQIGGIGGLAPERRHDLAKFGLRAVLGGTIATFMTATIAGVLTHFS
>NZ_CP015612.1|WP_088024366.1|750447_751413_-|ribokinase
MSSSVVVVGSFNVDHVWRCESLPAPGATIAGRYSTGPGGKGFNQAVAACRAGADTHFVCALGDDAGGATARELAAQDGFGLIAEASSEPTGTAGIYVDARGRNTIVIGPGANAALSTDFLQQQQALLTGAKVVLVQLESPVQTIEAALATAREAGVITVLNTAPADAPSTIGLLKLADVITPNETEFAALLGRHVGERVDANDVAALDGASLHALCRKLVGNGTVVVTLGSVGVFVSHADENLRGDTQPYYRVGAEQVQAIDTTGAGDAFNGALAASLAQVADAPFARHVRFANQFAGRSTEKEGAAAAMPRFTPGDVEVK
>NZ_CP015612.1|WP_088024363.1|749866_750298_-|hypothetical-protein
MDGFPWLLVAAAGSAIAALLHIGCIAFGAPWYRWFGAGPRMVRLAQAGHWWPPLMTAGITAVLVAWTLYALAAAGWHSPLPASRLVLSSIALLLLLRAAMGFGLALLRPGYNGRRFWVVSSLVCFGLGLGFALGARQAWQSLG
>NZ_CP015612.1|WP_088028233.1|748723_749719_-|tRNA-dihydrouridine-synthase-DusB
MQIGPYTIAPNVVLAPMAGVTDKPFRLLCKRLGAGLAASEMTISDPRFWTTRKSIHRMDHDGEPAPISVQIAGTEPQQLAEAARYNVDHGAQIIDINMGCPAKKVCNAWAGSALMRDEQLVARILEAVVNAVDVPVTLKIRTGWDCDHRNGPVIARIAENSGIAALAVHGRTRDQHYTGQAEYATIGEIKAALRIPVIANGDIDSPQKAAYVLKETGVDAVMIGRSAQGRPWIFREVAHYLATGEELPPPSLAEVRDILLGHLHALHAFYGEPQGVRIARKHLGWYAKDRPENAAFRAVVNRAEDPASQIALTSEYFDRLIAGEPALSSAA
>NZ_CP015612.1|WP_088024361.1|747722_748550_-|class-I-SAM-dependent-methyltransferase
MTPPISSPTYLHGFSGTEQQRLMTQARLLESSIFGQIDYSGARRLLEVGSGVGAQTEILLRRFPELHVTGVDLSETQLATARENLARTPWCSDRYTLQQADAGELPFEARSFDAAFLCWVLEHVPSPARVLSEVRRVLAPGSPVYITEVMNASFLLDPYSPHIWRYWMAFNDFQYDHGGDPFVGAKLGNLLLAGGFRDVHTEIKTIHLDNREPARRKTMIAFWEQLLLSAADQLLQAGSVDEETVEGVRREFRLVQNDPNAVFFYSFVQGRATVY
>NZ_CP015612.1|WP_088024377.1|758517_761034_-|FtsX-like-permease-family-protein
MNLLRHAWRALRREALAGDLLTVFAALVLGVAVMTAVGTLVNRVNLALTGSAAEMLGGDLGIAGRDDPPQAFADEAQRRGLAYTRIASFGSVLFHGEASQMASIKAVEAGYPLRGTLRVRATPGGALIDKAGMPAKGQAYADPRLLQGLGLKAGDDLEFGAGTLRIAGIIEAEPDTGGDLLTLSPTLLVNRADVEGTGLLGPGSRINYRLMFAGPADQIAALRQWLLPQVKGLRLLSVDDTQRGVRQAFDLAGRFLGLSALLAVLLAGVATALAANRFALRRIDQVAILRCLGARQRDILSGLALQLLMLAVPACALGIGLGMAAQEGLVQVLGSLVPQRLPLPEAMPALTGAGIGLLLLFGFGLPPLLRLRGVPPMRVLNRSFAALPPASLLAYVAALAASLLLAVQVTGDLKLALWVLGGLAALALAAGVVGFVLLQLLRGLQHRLHGNWRLGLAALTRRRLLAVMQLVGLSLSLCALLLLAVTGPGLLQQWRERLPADTPNYFLINIQPEQRDSVLATLRGLGANDASIEPMATGRLLAINGKPPLRVDRSPEQSGQQASGEAQRDDDDENRPLNFSWRSSFPPANTLVNGTFWKADSTAPEASVEIGWAKRYGVYPGDRITIAVGEQEREFTVTSVRKADWNTFRPNFFVLLNPNAVGDTPHNLLSAFHLPAGKAAGLGELVRAQPNLSLLDVDAVISQVRDVMERVAQAVQLVMVFSLLAGVLVLLAALQATAGERRYDSAVLRTLGATRRQLRGAVLVEFGALGTLAALLAVGAAAAIGVAVSQKVFELPLLPPWPGLLIGGVVGIGLSLLAGWWGTRRILHTSPALALREA
>NZ_CP015612.1|WP_088024380.1|761030_761678_-|ATP-binding-cassette-domain-containing-protein
MQGPEGEVHILDNITLTVHEGTSAAIVGASGSGKTTLLGLLAGLDLPSRGRIALSGQDLGDLDEEARAQLRAREVGFVFQSFHLLPALTAAENVALPLELAGREDRARVDEVLAQVGLAHRARHYPRQLSGGEQQRVALARAFVTRPRILFADEPTGSLDHATGQHISDLLFELNASSGTTLVLVTHDLRLAQRCQYIHRIDDGRLLPVERGAQA
>NZ_CP015612.1|WP_004144386.1|761753_762398_+|arylesterase
MRKTGWSRRAGVMMVLLLGFLLLPGLACAKGPAGTVLVLGDSLSAAHNIPADAGWVSLLQQRVRQQSKTPARIVNASMSGETTAGALTRLPGLLAKENPTVVVIALGGNDALRGLTPAQVQGNLEKMVQASQKAGAKVLLLGIDVPPNYGPAYRQRLAAAYKALATQYKVPLLPFLLEGVALQPGMMQADGLHPTAQAQPKVLDNVWPLLRPLL
>NZ_CP015612.1|WP_086016257.1|762452_763199_+|response-regulator-transcription-factor
MFHKAEVRGNHMRQTKETSGLVLVVEDNRNISEMIGEYLEGRGFEVDYAQDGLDGYRLAAENSYDVVVLDLMLPRLDGIEVCRRLRNDARKSTPVLMLTARDTLDDKLTGLGFGADDYLTKPFAIQELEARLRALIRRERRQVGSEVLKVADLVLDPVSMRATRAGTELQLSPIGLRLLTILMRESPRVVTRQEIEREIWGNGLPDSDTLRSHLYNLRKIIDKPFDRPLLHTVQSAGYRIADIAQPMA
>NZ_CP015612.1|WP_088024383.1|763356_764628_+|HAMP-domain-containing-histidine-kinase
MPHGLPRKIRIAFILQAVLASLGILLGAWLVSLVIKHSLVGAALREEAAYFWTLHEASPVQPPPNTQNIRGYLLESGQSALSLPANLRNLEPGFHELPKDDQLVLVDVRPAGRLYLVFLRSRAEMLAFWFGIVPVLLTLLAVYGASWVTYRASKRLVSPVNWLARRVSRWDPGHPEAADLEPNKLPADMQGETRQLAAALHSLANRVSAHVARERNFTRDASHELRTPLTVIRVASDMALGDDSLEPRLRRSLQRIQRAGRDMEAVIDAFLILAREADVEPQIELFDVNDIVRYEVDNANELLGTRPVSVHLHSDGPVQLHAPPRVLQVVLSNLVRNACSYTDEGRIDVHVHNDRVVVRDTGIGMSVEALSRAFEPFYRAEPSRPQGTGLGLSIVRRLCDRFGWKVSLASEPGEGTEATVIFR
>NZ_CP015612.1|WP_088024385.1|764997_765699_-|hypothetical-protein
MSRRRTCLLMLGLLTAAPLAQALSPAKPPRVPEQVSNVAWAGDMAHFASADQASPPPRGGIEFIGSSSIRFWESLATDFPGQPVFNRGFGGSEVRDSTWYAGQIVVPYAPCKVFFYAGDNDLNSGRSAVQVRDDVVAFVQRVHRDLPKTKVEYLSIKPSPSRAHLLPAINEANTLIKAALAKLPNTGFTDIYTPMLGADGQPDATLFREDMLHMTPAGYAIWTRALAPKVKCD
>NZ_CP015612.1|WP_049435654.1|765912_766308_+|diacylglycerol-kinase
MADQFGHLPRGPRRIFQAARWSWQGLRAAWLHESSFRLEVYLLILLTPVAIWLGQTPVERALLIGSMLLVLAMELANSAIEAVIERYGSEIHELAGRAKDMGSAAVFVLMMNVLLCWALVVVPHAMAGNYG
>NZ_CP015612.1|WP_005408127.1|766340_767090_+|TerC-family-protein
MSFEFLADPNAWVTLFTLSALEIVLGIDNLVFISIAVSKLPEERRPFARKLGIAVACITRIGLLVSLAYLAHMAANLFTVAGMGISIRDLVLIVGGLFLIIKGCMEIKELISGGEDEDPSTTKASAVFGYVIAQIAVIDIVFSLDSVITAVGIADHIPVMVAAILLSVLVMLLAANPLGRFIDANPTVKMLALAFILMIGAVLILDGLDVHVPKPYIYAAMGFSVLVEWLNLLMRRRAREHNVPGAGNW
>NZ_CP015612.1|WP_088024388.1|767337_768498_+|MFS-transporter
MNSRAALLALAVGAFAIGTTEFAPMGLLPIIADGVGVGIPTAGMLITAYAVGVMLGAPVMTLLMGRFGKRTALMLLMSIFVVGNLLSALAPNYGLLLLSRLVTSLNHGAFFGIGAVVAASLVPKDKQAAAVATMFMGLTIANIGGVPLATWVGQQLGWRLSFAGTAVLGLVAITALGLALPASAPGPRPDVRRELKAILQPQVLLAMATTVLGAGAMFTLYTYVAPVLTELTGASNAFIAMSLALIGIGFTFGNGIGGRMADWSLDGATRILLAVLAVLMFVLPLAFMNHATAALGVLLFGAATFAIVPPLQIRVMQAASEAPGLASSINVGAFNLGNALGAALGGAVISSGLGYAAIPVAGGLLAASGLLLAWLGRPRAAVAEAC
>NZ_CP015612.1|WP_088024391.1|769028_769649_+|LemA-family-protein
MRLFTRVLPLMLLASLLSGCGYNAIQQKDEAVKASWSEVINQYKRRADLVPNLVQTVKGFASQEERVLTEVTNARSRVGQINVNADDEASLKQFQQAQGELGSALSRLLVVSENYPQLKSNQNFRDLQAQLEGTENRVTVARGRYIQQVQDYNTYIRSFPQVITAKIFGYKTKPNFTVENEAQISNAPAVDFGNAPQQQPAPQPGH

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Crispr_ID: NZ_CP015612_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_4

1108307-1108381

Orphan

Consensus_repeat	Method
GGTGCCGTCCGTTGGTCGGCACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_4

>merge|NZ_CP015612|4|1108307-1108381|CRISPRCasFinder
GGTGCCGTCCGTTGGTCGGCACAATAGGAATTCACCTTGAACTGCCTGGGTGGGTGCCGACCGTTGGTCGGCACA

>NZ_CP015612|4|4|1108307-1108381|CRISPRCasFinder
GGTGCCGTCCGTTGGTCGGCACA	ATAGGAATTCACCTTGAACTGCCTGGGTG
GGTGCCGACCGTTGGTCGGCACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088024870.1\|1102506_1102956_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP015612.1\|WP_046983647.1\|1113619_1113889_-\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|273389
NZ_CP015612.1\|WP_005408377.1\|1106247_1106814_+\|YqgE/AlgH-family-protein	unknown	unknown	gnl\|CDD\|234694
NZ_CP015612.1\|WP_088024879.1\|1109102_1109900_-\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|226584
NZ_CP015612.1\|WP_088024881.1\|1109970_1110237_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088024883.1\|1111847_1113617_-\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP015612.1\|WP_046983642.1\|1107316_1108267_+\|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234849
NZ_CP015612.1\|WP_005408388.1\|1115614_1116565_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP015612.1\|WP_032130191.1\|1116561_1117014_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|334031
NZ_CP015612.1\|WP_088024874.1\|1104368_1106156_-\|DUF4153-domain-containing-protein	unknown	unknown	gnl\|CDD\|372672
NZ_CP015612.1\|WP_049444183.1\|1110297_1111659_-\|magnesium-transporter	unknown	unknown	gnl\|CDD\|225148
NZ_CP015612.1\|WP_088028269.1\|1103048_1103756_+\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP015612.1\|WP_088024885.1\|1113881_1114274_-\|PTS-fructose-IIA-subunit-family-protein	unknown	unknown	gnl\|CDD\|225446
NZ_CP015612.1\|WP_088024868.1\|1102197_1102410_+\|DUF4287-domain-containing-protein	unknown	unknown	gnl\|CDD\|379478
NZ_CP015612.1\|WP_088024872.1\|1103829_1104372_-\|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl\|CDD\|225374
NZ_CP015612.1\|WP_088024887.1\|1114702_1115587_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450
NZ_CP015612.1\|WP_088024876.1\|1106806_1107301_+\|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl\|CDD\|234639
NZ_CP015612.1\|WP_088024866.1\|1100890_1101787_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176163
NZ_CP015612.1\|WP_088024877.1\|1108494_1108983_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224854
NZ_CP015612.1\|WP_088024865.1\|1099864_1100848_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381304

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088024870.1\|1102506_1102956_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.92553e-13
NZ_CP015612.1\|WP_046983647.1\|1113619_1113889_-\|HPr-family-phosphocarrier-protein	gnl\|CDD\|273389	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family. The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS].	1.08365e-31
NZ_CP015612.1\|WP_005408377.1\|1106247_1106814_+\|YqgE/AlgH-family-protein	gnl\|CDD\|234694	PRK00228, PRK00228, YqgE/AlgH family protein.	5.72042e-86
NZ_CP015612.1\|WP_088024879.1\|1109102_1109900_-\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|226584	COG4099, COG4099, Predicted peptidase [General function prediction only].	5.79234e-38
NZ_CP015612.1\|WP_088024883.1\|1111847_1113617_-\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP015612.1\|WP_046983642.1\|1107316_1108267_+\|aspartate-carbamoyltransferase-catalytic-subunit	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	4.48202e-164
NZ_CP015612.1\|WP_005408388.1\|1115614_1116565_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.55323e-139
NZ_CP015612.1\|WP_032130191.1\|1116561_1117014_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|334031	pfam00359, PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.	3.48647e-32
NZ_CP015612.1\|WP_088024874.1\|1104368_1106156_-\|DUF4153-domain-containing-protein	gnl\|CDD\|372672	pfam13687, DUF4153, Domain of unknown function (DUF4153). Members of this family are annotated as putative inner membrane proteins.	5.14126e-15
NZ_CP015612.1\|WP_049444183.1\|1110297_1111659_-\|magnesium-transporter	gnl\|CDD\|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	4.25163e-161
NZ_CP015612.1\|WP_088028269.1\|1103048_1103756_+\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	2.66509e-40
NZ_CP015612.1\|WP_088024885.1\|1113881_1114274_-\|PTS-fructose-IIA-subunit-family-protein	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	1.62134e-25
NZ_CP015612.1\|WP_088024868.1\|1102197_1102410_+\|DUF4287-domain-containing-protein	gnl\|CDD\|379478	pfam14117, DUF4287, Domain of unknown function (DUF4287). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 70 and 180 amino acids in length.	4.19709e-23
NZ_CP015612.1\|WP_088024872.1\|1103829_1104372_-\|DNA-3-methyladenine-glycosylase-I	gnl\|CDD\|225374	COG2818, Tag, 3-methyladenine DNA glycosylase [DNA replication, recombination, and repair].	1.46338e-61
NZ_CP015612.1\|WP_088024887.1\|1114702_1115587_-\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	1.33415e-147
NZ_CP015612.1\|WP_088024876.1\|1106806_1107301_+\|Holliday-junction-resolvase-RuvX	gnl\|CDD\|234639	PRK00109, PRK00109, Holliday junction resolvase RuvX.	2.19161e-51
NZ_CP015612.1\|WP_088024866.1\|1100890_1101787_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176163	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 5. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.83136e-102
NZ_CP015612.1\|WP_088024877.1\|1108494_1108983_+\|hypothetical-protein	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.06235e-12
NZ_CP015612.1\|WP_088024865.1\|1099864_1100848_+\|aldo/keto-reductase	gnl\|CDD\|381304	cd19078, AKR_AKR13C1_2, AKR13C family of aldo-keto reductase (AKR). The AKR13C family includes Helicobacter pyroli aldehyde reductase (AKR13C1) and Thermotoga maritima aldo-keto reductase (AKR13C2). Aldehyde reductase (EC 1.1.1.21), also called aldose reductase, is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides.	0

>NZ_CP015612.1|WP_046983642.1|1107316_1108267_+|aspartate-carbamoyltransferase-catalytic-subunit
MTAQQIDASGRLRHLLTLEGLPRETLLQLLDRAGQIRDAAVGRVGNKRHVLAGSAVCTLFFEPSTRTRSSFQLAAQRLGADVLNFDASTSSTRKGETACDTLRNLEAMGVRGFVVRHPDDGAVAALAEAAGEGTALINAGDGRSAHPTQGLLDMLTLRQAKGPDFSKMKVVIVGDVKHSRVARTDLHALRTLGVGEIRVCGPQSLLPDDETLKGCVVGDDFDAMLEGVDALMMLRLQRERMEEGLVPSLEQYHAQYGLTNERLARAGKDAAVLHPGPINRGVEVTDEVADGPQSWVLRQVANGVAVRMAVLETLLG
>NZ_CP015612.1|WP_088024876.1|1106806_1107301_+|Holliday-junction-resolvase-RuvX
MSEPAAPAPVSPAPAIRRDGTVLGFDVGSRRIGVAIGSAFAAHARAVAVVDVHGNGPDWTAIERLLKEWKPDGLVVGDPLTLDGQDQPNRKRAQGFARQLRERFKLPVVMIDERSSSVEAARRFAVERAEGRKRRRDAAALDAVAAAVIIDRWLSCPDDATPIP
>NZ_CP015612.1|WP_005408377.1|1106247_1106814_+|YqgE/AlgH-family-protein
MPVTPTSLADHLLVALPSLLDATFARSVALICQHDENGAMGVLVNQPSEYTLGEVLAQMDITTGDGDLQARMVLNGGPVHPERGFVIHDDARAWDSSLTVGDGLYLTTSRDILEAMARGEGPANAVVTLGCAGWGAGQLESELSENSWLTVPADAELVFQLPLEQRWQGAASRIGVDLFRLTDYSGHV
>NZ_CP015612.1|WP_088024874.1|1104368_1106156_-|DUF4153-domain-containing-protein
MQSSSPLTLPARSAIVLIALLQGLMLYAAQELSDAWPFRDIGWRYCWYAWVLAIPSAVALSLVELGQRRLWMQAVFGSAVVLALAAWVGWNLNGETALDSGALQFPLTLGMAVAVFVALPWWQFQLQHGHWRASYPELFERAWQNGLTLALAALFTGLTWLLLWLWAALFQLLDVNAFRDLFRQDAFIALATGSLAGFGVLIGRTQHRAIQITRQVLFAICRGLLPLLSFIAVLFVLSLPLTGLEPLWKTRSAASLLLVLSLLLVTFTNAVYQQGEDSPPYPLLLRRLVEASLLALPIYAVLALYALGLRVVQYGWTLDRFWAVLIALAVAGYAVGYALAVLRRQSRWLQTLEPVNRWMCWAVLALALLGNSPLLDPVRLTLSSQLARLRADPPAITSSDVNVLRFDLGRRGVQALRGLQNDPAIRADANAPQVIADALARTSRWDGGTRLDKGPQDVAALQRALKLAKGSSSPPDDWWQALATRAINGESCAQSERDCLIVHRDLDGDGSTEVLLCELYTHRGPDCVLYARGRDAQWRRAGSLFGTASGQAEAINQALRDGELTLEPPRWPMLSIGGRPAVTIDPEPESNESSP
>NZ_CP015612.1|WP_088024872.1|1103829_1104372_-|DNA-3-methyladenine-glycosylase-I
MSGYCLIAPGHPVHDYYHANEYGFPQRDERELFERLVLEINQAGLSWETILKKREGFRTAYDGFDVDRVAAYTEQDIERLLSDAGIIRNRLKVLAAIHNAQVIQQLRASHGSFAGWLDAHHPRSKADWVKLFKKTFRFTGGEITGEFLMSLGYLPGAHAEDCPVHARLLTLSPPWLQASR
>NZ_CP015612.1|WP_088028269.1|1103048_1103756_+|YitT-family-protein
MSLPAHGPAPCDDADGHLVTAGPLTPPPDSAGTTADEKALRHSIAEDVQGMVLATMVASLGLAIFAKGGLMIGGMAGMAFLLHYAMGWNFGLVFVLVNLPFYWVALRRMGWEFTLKTFAAVTACGVLTDLLPRWIDFSHINPLYSAIVGGALSGLGILFFIRHRASLGGIGILAVYLQRTRGWSAGKVQMSYDACLMVAAFFVLSPSKVLYSAIGAVVLSLVLMFNHRPGRYMGV
>NZ_CP015612.1|WP_088024870.1|1102506_1102956_+|GNAT-family-N-acetyltransferase
MQVTLDAITVDNYDAVCDLDVSEAQQDFVAGNTWSLVQAAFHPGYQTRAILADGELVGFFMWVPETPQRTSIWRFMVDQRWQGRGIGRRALELALAQIRDTPGLAEIEICYNPHNPVAGAFYGSFGFVETGMDDDGEDMLAVLPVTPPK
>NZ_CP015612.1|WP_088024868.1|1102197_1102410_+|DUF4287-domain-containing-protein
MSTDTKPKGPASYFPSIEKTYGQPVAHWFGLLAGKKGLKHMELVSFLKGEHGLGHGHANALVAHHLAGKG
>NZ_CP015612.1|WP_088024866.1|1100890_1101787_-|LysR-family-transcriptional-regulator
MPRENLNDLQAFVHVAREGSFTRAAAQLGVSQSALSHAMRGLEERLGVRLLTRTTRSVSTTEAGARLLDTLAPRLAEIEDELAALAEYRERPAGTIRINATGHAAEYIAWPRLAPLLQQYPDLKVELAADYGLADIVAERYDIGIRLGERLARDMVAVPVSPPLRMRVVGAPSYFRQHVVPQHPHELADHNCVTLRLPTHGGLMPWDFGQDGNELSVRVTGQWTFNTMGMTRAAALAGSGLAWLPEDQVQPMLDDGRLRSVLDDWCPHFDGYYAYYPSRRHVTVAMRTVLDALRGPMG
>NZ_CP015612.1|WP_088024865.1|1099864_1100848_+|aldo/keto-reductase
MQTRELGRSGLKVSALGLGCMGLSHGYGQPVERSQGIALLQAAVERGVTFFDTAEVYGPYTNEDLLGEALAPYRDKLVIATKFGFKDARVDTGLDSRPENIRAVAEASLKRLRTDHIDLFYQHRVDPNVPIEDVAGTVRDLIAEGKVGHFGLSEASAATVRRAHAVQPVTAVQSEYSLWWREPERELLPTLQELGIGFVPFSPLGRGFLTGAINADTTFDANDFRNTVPRFEVEARRANQALVDRISTIAAARGATPAQVALAWLLAQAPWIVPIPGTTKIHRLEENLGAADLQLAQEDLQRIAQALDEVSIVGERYNAQRAAQAKG
>NZ_CP015612.1|WP_088024877.1|1108494_1108983_+|hypothetical-protein
MNRARLRLGRHSRIGQSYILTTVTQGRRRYFDDATAAQLVMDVVRRLDTEGLTYSLAYVVMPDHIHWLVELRAFSLDYVMQRFKSSSALLINRMLGRSGRFWQSSYHDHAIRSDESLLSHAMYVLGNPIRAGLTAQLGEYPHAWCRWGMEAGQAMEHFGSER
>NZ_CP015612.1|WP_088024879.1|1109102_1109900_-|prolyl-oligopeptidase-family-serine-peptidase
MVRSLSRWLPLLAVLMMTACTSLPDSARGRFEARAVKVEGETAYYQVFIPAGVQAAAPTHLPVILFLHGSGERGADGVKQTYAGLGPYLREHPDFPALVVFPQVPGHEEWSGRNNRAAVAALDATIAEFGADPARQYLTGMSMGGYGSWNIALDDPRRFAAIVPVCGAVLAPRAKRPTLFVEQVAQETDPYAVIAQRLRHTPIWIFHGALDDVVPPDDDRRLHAAFQSAAARDVRYTEFPEGNHNAWDATYADPAMWEWLFAQKR
>NZ_CP015612.1|WP_088024881.1|1109970_1110237_-|hypothetical-protein
MATTIENYFQPGWRDQQHTCPACEWKGCSRAMVMELDEDATEYDCPVCENPLLVVLHPDMVQVQAAAAEGNTEAQEQLDIIASFPRPQ
>NZ_CP015612.1|WP_049444183.1|1110297_1111659_-|magnesium-transporter
MAEAVRHDKTARQLRMLSDALDSGRLGPVRRLVNTLAPAEIGNLLESLPPGKRAIVWGLVDPEDDGEVLVHVGEEVRESLLADMDPDEIIAAVEDLDIDDLADLVEDLPDTVIDEVLKSMDRENRERLEQVLSYPEDSAGRLMNPDVVTVRADVNVDVVLRYLRLRGELPDHTDHLFVVSRRHQYLGRVSLAALVTHEDTTPINRLIDDEQPAIDVGESDQEVARQFSDHDWISAPVVDDNNILIGRITIDDVVDIIRGQAEHQALGAAGLDEDEDLFSPVWRAMRRRLMWLSVNLCTAFLASSVVGHFEGTIDKLVALAVLMPIVAGLGGNAGTQVLALMVRGLALGQVGASNARTLLWKEVRVALLNGVMLGSVLGLIVLAWFHSPGLSAVIAIALTCNLLFAALAGVLVPLTLKRFGFDPALASGIFLTAVTDSMGFFTFLGLATLVLLH
>NZ_CP015612.1|WP_088024883.1|1111847_1113617_-|phosphoenolpyruvate--protein-phosphotransferase
MPRARAGQLGSGQRPVQLLAGHGAARGTAMGRARVRLPHALEVAEQRVATNQVEAELARLHRAVDAARTEMHELRQRLQGALNQEVGEFLDLHALLLDDPELLFGLDELIRSGPYSAGYALRLQRDRLAKVFDGMDDAYLKSRMDDLDHVIGRIHAFLQPERPPVVKGLAGEILVCDNIAPSELAQLQAQGVVGIVTAAGSALSHSAILARSLHLPLIVNVPQLLSRIADGDVLIIDGADGSITANPQADNLRDYRVRLKEHAREQRELGRLRSKPSRTRDQVDIALLANAESLEDVTQAHALGAQGLGLYRTEFLFLQRNELPDEEEQFQTYRDAALGMSGRPVTIRTLDLGADKADRTGLTLSNEENPALGLRGVRLSLARPKVADTQLRAILRASAYGKLRVLVPMVSTREELLAVRRRMLKLTEQLRSEGHMVSDHVPLGAMIEVPAAALALESFIDLVDFLSIGTNDLVQYLLAADRNNEALGELYSPLHPAVLRLLQMVIETGARHRIPVAVCGEMAGDARMTPLLLALGLAEFSLHPGTLLEVRRAIREADLSVLRARAPKLLAARDRRAIERWLALVADTL
>NZ_CP015612.1|WP_046983647.1|1113619_1113889_-|HPr-family-phosphocarrier-protein
MLERELTVSNRLGLHARATAKLVQTLAPFRCNVTMAAKGREINAKSIMGVMLLAAGQGTPVTVRINGEDEAAAMEAVVGLFERRFDEDN
>NZ_CP015612.1|WP_088024885.1|1113881_1114274_-|PTS-fructose-IIA-subunit-family-protein
MTCAILLVTHPGVGTALLDVATRLLRQLPLKTEAFEVPFDADLDALLPLASAALRRVDGGDGVLILTDLYGASPANLAGQLARLGTPVRRVSALSLPMLLRVMNYPEQGLDQLPATAAAGTRNGAIVDDA
>NZ_CP015612.1|WP_088024887.1|1114702_1115587_-|RNase-adapter-RapZ
MSTATPSAPTLIIVSGLSGSGKSVALKTFEDQDYYCSDNLPIHLLPDFVRSLLANHDGSAPRRLAVGIDVRGQSDLSQLGNWRQLATDAGVEVKVLFFEASDETVLKRYADTRRRHPLSQLGLSLPEAIARERELTAPLRREADAVIDTSNLNVHQLRRRIITEFAMDHATGLSLLFESFAYKRGVPAEADFVFDARVLPNPHWDPDLRALSGREPGVRDYLEAQPDVQRYLTQLMDFLDTWLPKLGDGTRSYVTVAFGCTGGKHRSVFLAERMARHAREMGWEDVATYHREQD
>NZ_CP015612.1|WP_005408388.1|1115614_1116565_-|HPr-kinase/phosphorylase
MNTSITARELFEQQRERLGLRWAAGKSGEKRELEAGNTVSRRPSLAGYLNAIYPNKVQILGTEELSWLDALEPRQRWETIEKIMQSHPLALVLTRNQACPEDLRAAADESGTPLWLSPKRGHELLNHLSYHLARTLAPRVILHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVREMFGDTAVKKNKYLRLIVHLTKPMTEPTPHGYERLTGDSGTRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP
>NZ_CP015612.1|WP_032130191.1|1116561_1117014_-|PTS-sugar-transporter-subunit-IIA
MPLTDLLAAVQTQLCTATDRDSVLQAAAGLLACRQANAEQIYLNLCQREALGSTAIGHGIAIPHGRAPTLDRPRGALLRLATPVDFGGDEPVDLVFAMAVPAHYTHQHLMLLSELAELFSAPDIRQALREAGDARALREALDMTPPASAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015612_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_5

2198037-2198119

Orphan

Consensus_repeat	Method
TGCCCACCAAGGTGGGCACCTACCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_5

>merge|NZ_CP015612|5|2198037-2198119|CRISPRCasFinder
TGCCCACCAAGGTGGGCACCTACCAAGGCAGGGGCCTGTATCGATCGTGGATGGGGCTTGCCCACCAAGGTGGGCATCTACCA

>NZ_CP015612|5|5|2198037-2198119|CRISPRCasFinder
TGCCCACCAAGGTGGGCACCTACCA	AGGCAGGGGCCTGTATCGATCGTGGATGGGGCT
TGCCCACCAAGGTGGGCATCTACCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088028339.1\|2203436_2204177_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP015612.1\|WP_088025916.1\|2199080_2201366_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NZ_CP015612.1\|WP_032127363.1\|2194866_2195481_-\|high-frequency-lysogenization-protein-HflD	unknown	unknown	gnl\|CDD\|234690
NZ_CP015612.1\|WP_088025921.1\|2204249_2205518_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088025918.1\|2201830_2202118_+\|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|274228
NZ_CP015612.1\|WP_088025912.1\|2195477_2196620_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP015612.1\|WP_088025913.1\|2196616_2197078_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239647
NZ_CP015612.1\|WP_005409596.1\|2203131_2203350_-\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NZ_CP015612.1\|WP_088025919.1\|2202175_2202559_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088025920.1\|2202687_2202960_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_157664585.1\|2205998_2206637_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088025914.1\|2197079_2197553_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088025910.1\|2192752_2193100_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_010485867.1\|2193511_2194702_-\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|206779
NZ_CP015612.1\|WP_088025911.1\|2193197_2193413_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088025909.1\|2188622_2191382_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NZ_CP015612.1\|WP_088025915.1\|2198129_2198942_-\|APH(6)-family-putative-aminoglycoside-O-phosphotransferase	unknown	unknown	gnl\|CDD\|226100
NZ_CP015612.1\|WP_088028337.1\|2192168_2192633_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088025917.1\|2201543_2201822_+\|peptidase	unknown	unknown	gnl\|CDD\|282822
NZ_CP015612.1\|WP_010485856.1\|2197665_2197992_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088028339.1\|2203436_2204177_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.66587e-128
NZ_CP015612.1\|WP_088025916.1\|2199080_2201366_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NZ_CP015612.1\|WP_088025918.1\|2201830_2202118_+\|HigA-family-addiction-module-antidote-protein	gnl\|CDD\|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	6.59832e-27
NZ_CP015612.1\|WP_088025912.1\|2195477_2196620_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP015612.1\|WP_032127363.1\|2194866_2195481_-\|high-frequency-lysogenization-protein-HflD	gnl\|CDD\|234690	PRK00218, PRK00218, lysogenization regulator HflD.	1.65915e-86
NZ_CP015612.1\|WP_005409596.1\|2203131_2203350_-\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	7.64978e-48
NZ_CP015612.1\|WP_088025913.1\|2196616_2197078_-\|NUDIX-hydrolase	gnl\|CDD\|239647	cd03675, Nudix_Hydrolase_2, Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.34423e-69
NZ_CP015612.1\|WP_010485867.1\|2193511_2194702_-\|chemotaxis-protein	gnl\|CDD\|206779	cd11386, MCP_signal, Methyl-accepting chemotaxis protein (MCP), signaling domain. Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.	6.0076e-31
NZ_CP015612.1\|WP_088025917.1\|2201543_2201822_+\|peptidase	gnl\|CDD\|282822	pfam05015, HigB-like_toxin, RelE-like toxin of type II toxin-antitoxin system HigB. This family carries several different examples of type II bacterial toxins of toxin-antitoxin systems including many HigB-like ones. The fold is referred to as the RelE/YoeB/Txe/Yeeu fold suggesting all examples of these are present in this family. Several plasmids with proteic killer gene-systems have been reported. All of them encode a stable toxin and an unstable antidote. Upon loss of the plasmid, the less stable inhibitor is inactivated more rapidly than the toxin, allowing the toxin to be activated. The activation of these systems results in cell filamentation and cessation of viable cell production. It has been verified that both the stable killer and the unstable inhibitor of the systems are short polypeptides. This family corresponds to the toxin.	3.10655e-26
NZ_CP015612.1\|WP_088025915.1\|2198129_2198942_-\|APH(6)-family-putative-aminoglycoside-O-phosphotransferase	gnl\|CDD\|226100	COG3570, StrB, Streptomycin 6-kinase [Defense mechanisms].	3.25568e-77
NZ_CP015612.1\|WP_010485856.1\|2197665_2197992_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	9.35868e-44
NZ_CP015612.1\|WP_088025909.1\|2188622_2191382_+\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.37877e-106

>NZ_CP015612.1|WP_010485856.1|2197665_2197992_+|ATP-dependent-Clp-protease-adapter-ClpS
MPRESSPDSHHEHGVAVEPARPEVAPPPFYQVMLLNDDYTPMDFVVDVLQQFFSMDLDKATQVMLHVHTRGRGVCGVFTREVAETKVAQVNEYSRMNQHPLLCTMEKA
>NZ_CP015612.1|WP_088025914.1|2197079_2197553_-|hypothetical-protein
MKRTLLPALLIALAAAGSAAAETQADKAVARHLDKLGYTYEVDEDGDYRMVFDVEGDRTQMVYVRSSVEDFGTHNIREIWSPAYSAKTKQFPVAVANRLLEDSQDAKMGGWVKQDTTAMFVVKIDADATADQLSDAIDAAIRTADAMELELTKKDEF
>NZ_CP015612.1|WP_088025913.1|2196616_2197078_-|NUDIX-hydrolase
MNATPDPRWAPHATVATVVVDGGRVLLVEETIDGRQVLNQPAGHLEPGESLAEAALRETREETGWTVQLTHFIGCYQWTAGDGTAFLRFCYAACPVSHDPAQPLDTGIDRALWLTPAELQSAGERLRSPLVWQVVADFLGGQRHPLSLVREVA
>NZ_CP015612.1|WP_088025912.1|2195477_2196620_-|tRNA-2-thiouridine(34)-synthase-MnmA
MSTPRVMVGVSGGVDSSVAAWRLVQQGEAVAGLFMQNWADDGSGDCRAEDDRRDAVAVCGLLGIPFHFRDFSSEYWQGVFEHFLAEYAAGRTPNPDVLCNREVKFKHFLDAARELGAERIATGHYARVTQRGHQWLLLRGADRSKDQSYFLHQLGQEQLAATLFPIGDLEKTDLRRIARDVSLPTHAKKDSTGICFIGERDFREFLGRYLPAKPGQILDPADGSVIAEHPGVFYFTLGQREGLNIGGVRGRPAAPWYVVGKDVASNVLYVDQDRDSKWMLSERLRSETAHWIAGSPPARRFECTAQTRYRQPDEPCTVEVLDDGSVLVTFARPQRAVTPGQSLVLYDGDVCLGGAVIAATDAPLEQRLRTIPSPFEVIAA
>NZ_CP015612.1|WP_032127363.1|2194866_2195481_-|high-frequency-lysogenization-protein-HflD
MSFTVDDRVLALAGIAQALQQVRRIADTGHSDAAAVRTAVDSVFRVDASSPQEVFGDRHALKAGLRLLHNYFRSQGQDPILPKLALSVLQLERRFVQDGATVNKVASGIERAQRQAVELGDSGHPDVLANLGGLYADTISHLKPRVMVQGNPHYLGQAGVVAEIRALLLAAVRSAVLWRQLGGSYWDFLFSRKAMIEAVDRQLA
>NZ_CP015612.1|WP_010485867.1|2193511_2194702_-|chemotaxis-protein
MYSRIFIRLAAPLALTLLLPFAIGFEWPAALRWAILTTMTLSWLGFAWWTTRAQAHRSPEHARVLREQDQLLTELRNFVGNEIDGSRGEVERARDLIRQAVSSLGGSFDAMNRKSRQQSQALSRIVDRAGDEGNAGLDVARFAQHASHRMEQLVEALEQVSGQSSTTVQHIDQMAQHLDGIFALLEDVKSIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLSERSTTFNEQIRKLAHSSKDAIAKVRETVSHMASRDMDRSREARQEAAAMLDNVAQINASLGDGMREVSECARSIDGSVAEAVRALQFEDIATQALGGVHTHLDRLTAINREAVALQELLHRNGGVFDEEIATALQRTGSRLRELRSEWERPPHKPVAQQSMGAGTVELF
>NZ_CP015612.1|WP_088025911.1|2193197_2193413_-|hypothetical-protein
MTLIRALPSLTDTERPRNASVREQLQQLEEVAREEIRELQQLADARPALSRTDDALLGLAWDLGLDGEALR
>NZ_CP015612.1|WP_088025910.1|2192752_2193100_-|hypothetical-protein
MSTTFMTWLGFAVMVLIAVTFTWRPAYATLRPPRHRPVAFQFGSLLFMLMAFLFAWAPATAINTGHVHLSHHRSGTIDVWREIEPVIFWLIIVAAYVLGLLIASYSIAGIALMNR
>NZ_CP015612.1|WP_088028337.1|2192168_2192633_-|hypothetical-protein
MTFNPEEAQEAFEQFLIIMDDQIEWLIEQAQQRGVDLDRSLESLDRLETLYTTMAATQSEDEQEGLRIVFARYLGDVVWEHHGGKWTLPLDDPKDINFNMPVIVGHSSCPWLEFNPIHTMHCYALRPKAGMLRSIVAHSVDPQILDLSDLVEED
>NZ_CP015612.1|WP_088025909.1|2188622_2191382_+|EAL-domain-containing-protein
MDQGIIASLLQHPLASALVIVDRTGRPLAANPAAREHGLPATVAAYAPMLEDLRLMAADGGIVACTLPGGPHGHYDGHLRAVHDGAGNLLAFTLSIPEPVPLSGGGRWELALDSAGHSLWDWDIPSDRVVRTPALGDETATEILARVHNEDIAQVRAALDEHLRGLSEQYSAQFRFRQADGQWRWVLDRGRVVARTADGQPLRMVGTHTEIEQQKQLESLLQEQQLHLSEAQRIASMGSWSFDPGTGHFWWSPELRSLLALEQGAVPGQRRWLKQLHPRSRGALRAAWRRLWRDGRAANLELELTRGNEPSQHLRLWIQPLLDMDGQPKRLLGQVQNITEQHQTDALIRWRTELLNRVSALGRIGGCEIEVQTRHMQWTEECYRIHGLRKEPITLDQAMALYTEDSRNAFEAALGRIAAGGLPEQLDLCFYRQSGLRVWVQVLIELDRRDGLPPRFVVLFRDITREREANERIELLAHYDLLTGLPNRVLLGEQTAEAIEEARDRGTSLAMLFIDLDGFKTINDSFGHATGDALLKAAATRLHQNLRNNDLFGRFSGDEFIVVLRDLAEPEDAGHVARKLIASLAEPLRRGETTLKVGASVGIAMLGDAQTDFDSLLRAADAAMYAAKEAGRNTYQYYSQDALARIQRKLELEHALHGAIERDEFSLAYQPLLHAHHGEPPAIEALLRWHRPGFGYCSPAEFIPIAEKCGEIVRIGDWVLNEACRQAIAWDRAGLCFDRIAVNVSAVQLRDRGFAERVIEICHAHGWPPQRLELELTESALIRDTDILRHCFDVLERHGVPLAVDDFGTGFSNLNYLNRFPVGRLKIDRSFVQGMLHDSGTAEVTQAIVHLGHALGMKVVAEGVETHQEEDMLRRQGCDEIQGYLYSRPLSPRDLAQWLRQQHPAPMRTDASGEVVLVR
>NZ_CP015612.1|WP_088025915.1|2198129_2198942_-|APH(6)-family-putative-aminoglycoside-O-phosphotransferase
MSEPYLSRWRLRRDGAAIETPHALLWPVLTAAGEAAMLKVSSETEEQNSHRLLRWWDGDGAARLLAHEGPAILIERARGDSLRQRSIDGDDDACTTILCQVLQRLHRPRSAPPAELVCLHTWFADLLQPRAVLPPLLEQCRSLAEGLLQQEQEIRPLHGDLHHDNVLDFGARGWLAIDPKRLLGDRAFDYTTLFSNPDLCGPGIHVATQPERFAARLEQVSALAGLERTRLLRWIAASAGLSAVWFRDDGDPAEVDEAVARMALEALAEG
>NZ_CP015612.1|WP_088025916.1|2199080_2201366_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MFSKDLEHTIGQCYKRAREARHEFMTVEHLLLALLDNPSAQAVLKACGADAERLRQELEQAIEASVSRLAEDDGRDTQPTLGFQRVLQRAVYHVQSSGKKEVTGANVLVAIFGEKDSHAVYYLNQQDVTRLDVVNYLSHGIAKLGEEGEQPSSSSEGEGRIEGGEGEPKGDALAEFASNLNEQARAGRIDPLVGRADEIERTIQVLCRRRKNNPLYVGEAGVGKTAIAEGLARRIVEGSVPEVLADAVIYSLDLGALVAGTKYRGDFEKRLKSVLTALKKVPNAVLFIDEIHTIIGAGSASGGTMDASNLIKPALASGELRCIGSTTFQEYRGIFEKDRALARRFQKIDIVEPTVGETYEILQGLKSKYELHHGVTYSDEALQAAVDLSVKHIGDRLLPDKAIDVIDEAGARQRLLPEGQRKELIDVEEVEAIVAKMARIPTKQVSATDKDVLQHLERNLKMVIFGQDPAIETLSSAIKLARSGLGNPEKPIGNFLFAGPTGVGKTEVTKQLALQLGIELVRFDMSEYMEPHSISRLIGAPPGYVGFDQGGLLTEKIVKTPHCVLLLDEIEKAHPDIFNILLQVMDRGVLTDTNGREANFKNVVLVMTTNAGAAQASRRSIGFTKQDHATDAMETIRRSFTPEFRNRLDAVVQFQALGFEHILRVVDKFLIELEMLLQDKHVSLSATPTARDWLAHHGFDPLMGARPMARVIQDKIKRPLADELLFGKLVNGGKVSIDVRDDELVVETQAEPERLLPVTVE
>NZ_CP015612.1|WP_088025917.1|2201543_2201822_+|peptidase
MIMSFRHKGLERLYRTGSSSGIRQSHASRILMILSILDAAASPADLAMPGLRLHPLRGTLKGYWSVWVNGNWRITFRFVGSHVELLNYLDYH
>NZ_CP015612.1|WP_088025918.1|2201830_2202118_+|HigA-family-addiction-module-antidote-protein
MIHHHPHPGLTIKAMVFDPMELSVTDAAERLAMSRVALSRVLNGKAGISPDLAIRLEMAGVSTAVFWMGLQSNYDLWVARQREQPRVVPLIKPAG
>NZ_CP015612.1|WP_088025919.1|2202175_2202559_-|hypothetical-protein
MNALLLHVLLPAVLLASLPLSAPAAEPAKPSTPTECIALGTSRDIRPSNTEREVLLRDGNNHYRVHLQKRCLGAAASASYVFFTPNTPEQICGDARSTLQTDSNHCTVTRIEPVDAATFKRLAQQGR
>NZ_CP015612.1|WP_088025920.1|2202687_2202960_-|hypothetical-protein
MTYLIVLDPQSVTSRCYASKGPDGTWFGQPCLVCTSMDASHPLYLAVQREIPHMGSTLKQRLHIPHEAVAFVIEGGGDQGRQQGFRSIAA
>NZ_CP015612.1|WP_005409596.1|2203131_2203350_-|translation-initiation-factor-IF-1
MSKDDSIEFEGTVSETLPNTTFRVRLENGHEIIAHISGRMRKNYIRILTGDRVKVEMTPYDLTKGRITYRMK
>NZ_CP015612.1|WP_088028339.1|2203436_2204177_-|leucyl/phenylalanyl-tRNA--protein-transferase
MTRQLPWRLADAPDAPFPPAETALRQPDGLLAVGGDLHPVRLLNAYAGGIFPWFSEGEPILWWSPDPRMVFRTDGVHLSSRFRRQLRSSTWEITADTAFSRVMRACAAAPRPGQDGTWISPAMVEAYSQLHDLGFAHSFEVWDRQTLVGGIYGVAIGAMFFGESMFSGASGGSKIALAALASTLHGWGWELIDAQVENPHLLRMGAEHLPRADFLKHVRLAVHRDGREGPWTQAVGRLPARRLAGG
>NZ_CP015612.1|WP_088025921.1|2204249_2205518_+|hypothetical-protein
MSDSISAILDLHDAPRTRNDSQGMLLSLATEQPRRLGELMLQALARPSPSSAFLDMALDLLPDGVVPTVAADAWRRYRAGERGDVLTSVMEFASYQAPQVLQDDWEALLAVAGEDEVQLAAQVWQGLPSATAAHWAQILAEADDDREMARARALLLAAQPETYTVARGYLVDWGQLDTEVWAHWAGAANSPQPRRLHGERPLHIRFGREQHRAQQADEPSWRKRIWRLHPTWNGGQVHHAGHMGGPLEALCGSCHAPLQRLLRTEAAALQPGAAGEITLGLCLDCCGWEDPPVRFYRHDSAGLPSCHPGQYREVPNTPTDSGDLMQAEVGLAAMDTTRWQQQDWGQSNHRQNLSRVGGAPSWVQSAWYPTCIDCGEEMPFVMQLDSTLPTTGGGTLLWGSGGMLYTFWCAKCRVSGHFWQCT
>NZ_CP015612.1|WP_157664585.1|2205998_2206637_+|hypothetical-protein
MKFFVMSRLKEPGCPGLVEAFIVDKGHPHLCDHYYADNARCKRPLWHRRREGEYAPVFQPEMIAVNWDARWRFDICSASQGAYFASDRFMEISRNAGAGFVDQSPLTVRSKRGVDLVQFSYNAVIFKELDVLDVAAPESLLVRDRTYGHIHRVKTLVVREGFVEPIFRFKGMSGSSHTLICSEEFRQAAGQRLKGVEFIDIDGAIWPHIKII

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015612_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_6

2516002-2516119

Orphan

Consensus_repeat	Method
CATCCACGCATGGCGTGGATCTACTGCAGAGCCTGCTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_6

>merge|NZ_CP015612|6|2516002-2516119|CRISPRCasFinder
CATCCACGCATGGCGTGGATCTACTGCAGAGCCTGCTCTGGTGGGTGCCGACCGTTGGTCGGCAGTGGGCCAGCCCCGCCATCCACGCATGGCGTGGATCTACTGCAGAGACTGCTCT

>NZ_CP015612|6|6|2516002-2516119|CRISPRCasFinder
CATCCACGCATGGCGTGGATCTACTGCAGAGCCTGCTCT	GGTGGGTGCCGACCGTTGGTCGGCAGTGGGCCAGCCCCGC
CATCCACGCATGGCGTGGATCTACTGCAGAGACTGCTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088026174.1\|2513998_2514451_-\|general-secretion-pathway-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088026179.1\|2528967_2530143_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|270283
NZ_CP015612.1\|WP_088026182.1\|2534668_2537050_-\|type-II-secretion-system-secretin-GspD	unknown	unknown	gnl\|CDD\|274175
NZ_CP015612.1\|WP_088026169.1\|2507014_2508760_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374891
NZ_CP015612.1\|WP_088026173.1\|2513571_2513907_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088026181.1\|2533238_2534672_-\|type-II-secretion-system-ATPase-GspE	unknown	unknown	gnl\|CDD\|131585
NZ_CP015612.1\|WP_088026176.1\|2515009_2515372_+\|type-II-secretion-system-minor-pseudopilin-GspI	unknown	unknown	gnl\|CDD\|273767
NZ_CP015612.1\|WP_005409874.1\|2509506_2509920_-\|biopolymer-transporter-ExbD	unknown	unknown	gnl\|CDD\|223917
NZ_CP015612.1\|WP_088026170.1\|2508801_2509467_-\|TonB-family-protein	unknown	unknown	gnl\|CDD\|223880
NZ_CP015612.1\|WP_088026175.1\|2514566_2515013_+\|type-II-secretion-system-minor-pseudopilin-GspH	unknown	unknown	gnl\|CDD\|130769
NZ_CP015612.1\|WP_088026180.1\|2532031_2533231_-\|type-II-secretion-system-inner-membrane-protein-GspF	unknown	unknown	gnl\|CDD\|273980
NZ_CP015612.1\|WP_088026184.1\|2537570_2538734_-\|general-secretion-pathway-protein-GspL	unknown	unknown	gnl\|CDD\|273768
NZ_CP015612.1\|WP_088026185.1\|2539645_2540083_-\|type-II-secretion-system-major-pseudopilin-GspG	unknown	unknown	gnl\|CDD\|130771
NZ_CP015612.1\|WP_088026171.1\|2509930_2511715_-\|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl\|CDD\|227622
NZ_CP015612.1\|WP_049463074.1\|2530543_2531719_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|270283
NZ_CP015612.1\|WP_088028368.1\|2538730_2539636_-\|type-II-secretion-system-minor-pseudopilin-GspK	unknown	unknown	gnl\|CDD\|377165
NZ_CP015612.1\|WP_088026178.1\|2516383_2528767_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|372178
NZ_CP015612.1\|WP_088026172.1\|2511753_2513370_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP015612.1\|WP_088026177.1\|2515368_2515983_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|227132
NZ_CP015612.1\|WP_088026183.1\|2537046_2537574_-\|general-secretion-pathway-protein-GspM	unknown	unknown	gnl\|CDD\|377391

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088026182.1\|2534668_2537050_-\|type-II-secretion-system-secretin-GspD	gnl\|CDD\|274175	TIGR02517, Putative_type_II_secretion_system_protein_D, type II secretion system protein D. In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP015612.1\|WP_088026169.1\|2507014_2508760_-\|hypothetical-protein	gnl\|CDD\|374891	pfam16930, Porin_5, Putative porin.	0
NZ_CP015612.1\|WP_088026179.1\|2528967_2530143_-\|alkaline-phosphatase	gnl\|CDD\|270283	cd13565, PBP2_PstS, Substrate binding domain of ABC-type phosphate transporter, a member of the type 2 periplasmic-binding fold superfamily. This subfamily contians phosphate binding domain found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.92719e-27
NZ_CP015612.1\|WP_088026181.1\|2533238_2534672_-\|type-II-secretion-system-ATPase-GspE	gnl\|CDD\|131585	TIGR02533, Type_II_secretion_system_protein_E, type II secretion system protein E. This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP015612.1\|WP_088026176.1\|2515009_2515372_+\|type-II-secretion-system-minor-pseudopilin-GspI	gnl\|CDD\|273767	TIGR01707, Type_II_secretion_system_protein_I, type II secretion system protein I. This model represents GspI, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspJ. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.	2.08821e-15
NZ_CP015612.1\|WP_005409874.1\|2509506_2509920_-\|biopolymer-transporter-ExbD	gnl\|CDD\|223917	COG0848, ExbD, Biopolymer transport protein [Intracellular trafficking and secretion].	8.7853e-35
NZ_CP015612.1\|WP_088026170.1\|2508801_2509467_-\|TonB-family-protein	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	1.24557e-07
NZ_CP015612.1\|WP_088026175.1\|2514566_2515013_+\|type-II-secretion-system-minor-pseudopilin-GspH	gnl\|CDD\|130769	TIGR01708, Type_II_secretion_system_protein_H, type II secretion system protein H. This model represents GspH, protein H of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	4.06273e-19
NZ_CP015612.1\|WP_088026180.1\|2532031_2533231_-\|type-II-secretion-system-inner-membrane-protein-GspF	gnl\|CDD\|273980	TIGR02120, Putative_general_secretion_pathway_protein_F, type II secretion system protein F. This membrane protein is a component of the terminal branch complex of the general secretion pathway (GSP), also known as the"Type II" secretion pathway. The GSP transports proteins (generally virulence-associated cell wall hydrolases) across the outer membrase of the bacterial cell. Transport across the inner membrane is often, but not exclusively handled by the Sec system. This model was constructed from the broader subfamily model, pfam00482 which includes components of pilin complexes (PilC) as well as other related genes. GspF is nearly always gene clustered with other GSP subunits. Some genes from Xylella and Xanthomonas strains score below the trusted cutoff due to excessive divergence from the family such that a sequence from Deinococcus which does not appear to be GspF scores higher. [Protein fate, Protein and peptide secretion and trafficking].	7.53702e-161
NZ_CP015612.1\|WP_088026184.1\|2537570_2538734_-\|general-secretion-pathway-protein-GspL	gnl\|CDD\|273768	TIGR01709, Type_II_secretion_system_protein_L, type II secretion system protein L. This model represents GspL, protein L of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking].	2.75598e-18
NZ_CP015612.1\|WP_088026185.1\|2539645_2540083_-\|type-II-secretion-system-major-pseudopilin-GspG	gnl\|CDD\|130771	TIGR01710, Type_II_secretion_system_protein_G, type II secretion system protein G. This model represents GspG, protein G of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.26785e-56
NZ_CP015612.1\|WP_088026171.1\|2509930_2511715_-\|MotA/TolQ/ExbB-proton-channel-family-protein	gnl\|CDD\|227622	COG5306, COG5306, Uncharacterized conserved protein [Function unknown].	3.69018e-43
NZ_CP015612.1\|WP_049463074.1\|2530543_2531719_-\|alkaline-phosphatase	gnl\|CDD\|270283	cd13565, PBP2_PstS, Substrate binding domain of ABC-type phosphate transporter, a member of the type 2 periplasmic-binding fold superfamily. This subfamily contians phosphate binding domain found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.6855e-29
NZ_CP015612.1\|WP_088028368.1\|2538730_2539636_-\|type-II-secretion-system-minor-pseudopilin-GspK	gnl\|CDD\|377165	pfam03934, T2SSK, Type II secretion system (T2SS), protein K. Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.	1.63873e-32
NZ_CP015612.1\|WP_088026178.1\|2516383_2528767_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|372178	pfam12545, DUF3739, Filamentous haemagglutinin family outer membrane protein. This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam05860.	2.0477e-44
NZ_CP015612.1\|WP_088026172.1\|2511753_2513370_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	1.3711e-75
NZ_CP015612.1\|WP_088026177.1\|2515368_2515983_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|227132	COG4795, PulJ, Type II secretory pathway, component PulJ [Intracellular trafficking and secretion].	1.07379e-15
NZ_CP015612.1\|WP_088026183.1\|2537046_2537574_-\|general-secretion-pathway-protein-GspM	gnl\|CDD\|377391	pfam04612, T2SSM, Type II secretion system (T2SS), protein M. This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.	9.26e-15

>NZ_CP015612.1|WP_088026177.1|2515368_2515983_+|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MNHAVRGFTLIEVMIAITIMGVLALICWRALDSVASSDQRLRQADAETTTALRVLQQFQRDIEMRADDALMNGAVRPTDQPQRLLPPSLVSERHPDGSFALEITRSVGSDGLRWQRVRWWRQGNTLWRASGAATDRYPLPAPEQSKGIAVASDVQRFEVRAWQPGAGWAVLPSEGEVLPASGLELRLGLRDGRGPLNYRRVLEL
>NZ_CP015612.1|WP_088026176.1|2515009_2515372_+|type-II-secretion-system-minor-pseudopilin-GspI
MKRNVRGFTLIEVLIALAIVSIALAAVMRSVAVATDDQSRLRDRRLALMCAQDRWQELRLSGLAPQDTRYRCVQGRGSFLVLQHLGTGSDGQPQLELSVVAEDAPRQSLARMQLPWTVAQ
>NZ_CP015612.1|WP_088026175.1|2514566_2515013_+|type-II-secretion-system-minor-pseudopilin-GspH
MQHVPRGFTLLELMVVLVIIGICTAGIGLGLGSLLDPARQLRQEAERLAQRLQVARDEARIDGRTLRWQADADGYRFSRREGSRWVTVERDDLLRPQKWQATGIAVQPATPIELSPEWIGIAWELGLSLDGRTLRLRDDGSGQLQVVQ
>NZ_CP015612.1|WP_088026174.1|2513998_2514451_-|general-secretion-pathway-protein
MDGRRWDRNRMLTLLAATLLLAVVTYWGVTLSAVAPAAAASEAKAEAPVRPMFDAVASLPLVRLLSPGAVRTEVVVLGVMAGDHAPLALLEVDGRPAEAYSPGQRLGPCTVLASISASAVELNQAGQSRSLPVPELPPVPTDGIVPASSL
>NZ_CP015612.1|WP_088026173.1|2513571_2513907_+|hypothetical-protein
MSDLLKAGLRPALVLALLLALPSARADEAKKQEDAAPCIEVQVNGERIPAWECLQRKLAPASKAPKSPALPEAERLMRQPGNQLMQYNLEGTRQRMGDAFGRSVVPQRPAR
>NZ_CP015612.1|WP_088026172.1|2511753_2513370_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MTPVPCRAVRLPLRLHPLVLALAAMPLPLFAQEAAPAPSVNINEYIVRGNTVLDPRDIERAVEPFLGPGKTLADVEKARDAVNALYQQAGYQSVYVELPEQQVSGGVVLLKVQQTPIGQLRVVGTKHESPERIRERVPALAEGKVPDFDQAQKELTALNEGGRRQVLPLVREGQVPGTMDVDLQVEEKSPWRASASLNNDHSADTEKLRLSASLAYDNLWKRGHSANIGVYLAPEDTKQAKVFSASYMMPFEGTPWSLEASGYTSDSRVLNAGGQVGTGTGTNVIGNGHSIGLKLNYRLAGSSQWWRQLSLGVDFKDTEEDTQMGKDSLKTPLKYAPITLAFVGVRQGEHDQLSINTQLVAGTRRLFGYGSNAIGFGQKRYWADPSFVAFKADVANTHTFGSDWQWYARGSLQVTDAPLVSAEQFAAGGMYTVRGYLSAEAIGDYGGLASLEWRTPAWSLWSGTDLRVYSFADAAYLRLRQPLPDQRGKYNLASVGLGAQLRLGEHLQLRLDYAWPYADGPVTRKDDPRLHFNISTSY
>NZ_CP015612.1|WP_088026171.1|2509930_2511715_-|MotA/TolQ/ExbB-proton-channel-family-protein
MDRLLSRVLLLLAALVALPAAAADANWWQAEWKYRKPITVDAGPQGAGLAGDPGRTPLLLRLHTGNFGFDGTQDAGNDLRFVSGDGRTVLAHQIEQFDPKLGLALVWVDVPAVSAAAPQTIWMYYGNEKAPASGNGQQVFDPDYTLVYHFAEANAPARDTTAYGNNAGAVVPPSEGSVIGRGVQLGAGPLPLPASASLAQEAGTPLTISAWIKPGSNNAAQAIYARRDGASELVVGIENRVPFVQLNSQRSTPAQPIPEGQWAHVALTAEKGALQLYLNGRVVAQLSGELPALATAPVVGADAPGAAQPLANFEGALDELRISRVARPAALLLADATAQGADSRLISYGADEQSAGQSHFAFILKAMPFDAWVVVAILGLMMLLSWAIMIAKSRHFGRTSKANAVFTESFGKLSGVPLRTLSDMDRQGKAPTAMHDGSLWRIYQVAIDEMQQRHQRDGNSGYLSGATIAAIRASMDAVMVREQEAMARRMNWLSTTIEGAPYVGLFGTVIGIMLVFVVAAMAGAVDINSVAPGMAAALLCTAAGLGVAIPALFGYNYLGARAEAIGADMAVFIDEFAARLAEEQDGRGPAAVQG
>NZ_CP015612.1|WP_005409874.1|2509506_2509920_-|biopolymer-transporter-ExbD
MGQKAKFGIKKREKGINVTPFVDVLLVVLVIFILTSNASIPGIEVNLPKASNSVALEKPKTKAITIDPSGQVFLDAYPVTMAELEDRLRTERATTPDFPVIVRGDAQVQYARVVEVLDLLRRLELAQVGLVTGKAQG
>NZ_CP015612.1|WP_088026170.1|2508801_2509467_-|TonB-family-protein
MRGRQLLVTVALVLAALLVLGIAVWWMLFKDTASTRRPVVQPPMLALPPPPPPPPPPPEKPPEPETPPEEAMPEPEPLDQPTPAEEPTPTPDNSDPVTMNADAQAGGDNFGIQSGSGGGSSGVGRGGAGNATYGRYLGYLMQQAISRDDKVKRLAFQLQVNVWLANDGRLEKVELVRGSGNEEADAAVLDALRRIGKVDQAPPPSLDFPARVLIQGRRPGA
>NZ_CP015612.1|WP_088026169.1|2507014_2508760_-|hypothetical-protein
MNDHVRARTDSRRPRPARRALLCCAVLLSLAAPAGAMAAETTMVKLIKGLIASGALKPEDGQALLVQAEAEAAAAQRGAATAPSAASGGVALEAGDVRVPYVPQSVRDGIRDEVRQDVMAQAKSEGWAAPNEVAEWTKRIKVTGDMRVRSESRFFSERNSDIVSNWSSINSGNGFDTNTNTNLQLPPLLNTRQDRRNLWRIRARLGIEATIGQHTTAGVRLASGSSNGPVSTTEQLGGGLSKKDVWLDQAWLAYSPADWVTVRGGRFGNPFWTSDTLFSNDLNFDGLAANLKYDFDGGDLDLFGNLAVVPLEYTSDSSPSQSKVKTPNENKWLSGAQVGVNWRFNDDNALRAALGYYDFKNISGRLSSTCSLYSGAVGCDTDWSRPAFMQKGNTLMLIRNIARNPVDPAGTPTPQYVGLASAFRLATLNLRWDTQLAQGIGLRLDGDYIRNMAYDKQAMFSRAQNGIVNNYGAGDTVGIDTFRSGDTAWMLQATFGATELKEKGQWQALLGYKHIEADALPDAYNDPNFHLGGTNARGYYVGGAYALDARSWISGKWMAAKEVSGAPLSIDVFQLEFNTGF
>NZ_CP015612.1|WP_088026178.1|2516383_2528767_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MSHPLPSAVHPAAPMRRNHPMAWAIAVALGSMVAPASQAQQAFSPGWFADRGAAQGSAAQSGRMPNGVPIQFQLPAQQQDAARQKLQQSIDNLGTAAQAIALQQRLQEQARQARREAGFIVADGLGKDGLSVDQNPLTRGWLNAREAIQSQGSDGRVQVTVEQTADKAILNWETFNIGGNTTLNFLQNPDWAVLNRVNDPAARPSQILGQLNANGTVFVANRNGVVFGNNSQVNVRNLLAAAARISDAQFRDNGLYSPDASSSALSDAFGKVMVEQGARIATHEPTSATRGGGYVLLAGHSVENAGQIEARKGQVQLAAGDSFVIRRGVGTATNTSSTTRGNEIAPRFIAGSTAGNVRNAGLLRAREGDVTLAGRSVEQAGVAVASTTLAQRGTVHLLASASDAGSSVTLADGATTAVLIEDDGKATVLDTQRNSLIKESAEQDAIRAGARSATFDNLSQHNDRRDQSRVEIVSGGNIHFSADSLTVATGGQIIADAAARSYVGDAARVDVSGAVGVQVSMESNNVQVKVQGNELRDALDNRDSGKLTSSEIWVDRRRLVHVPAGTGGYEGERWYAAGGLLEVGGYLDNQGHSIGEWAAQGGTVLLGGREVITHGGSRINLAGGSLDVQSGVIRQSWVRGVDGQVYRLDDAPAEMLFDGLYSGHEVKQERWGITETFRDPIVFAAQRVDNGYTVGRDAGRLIVSAPTAVLDGQVETATFQGAQQNRRPDSALEGYAQAQTAAARNAQLYLGRYDGQGRSGVFGSEVRLDDKAPTKAAWSLLAPVNEERRDTVWLDTAELSAQQWGRIDLATADRIRIDGSLRLQAGGQLNLTGSEVELAGDIGIAGGQLSAGNLLDVQGRPTALLHDGRARTAIADGTRIDLSGEWSNASLAMPLDASGAWTDGGRLSLSNSHDVVVGAEATVDVEAGAALDLRGKGRIGKGGSVSLQANSSTVATDGSGRVQLGEGSRFSGRGQGSGTFSLGTGGRVRVGNADPADPAALQVDAGLFGSGFAQYDINGHQGLEVADGTQLAARMPGLRMTADARVATDRKEALESWLAPLYSADPMSGLVRQRSGASVSLRSDRNSVGGDLRVGKAALIEVDPGQAISLLGAGNIDVEGTLRAQGGRISIDDVRLPTTLYAGRRSERTWRFADGALLDASADAVSLADAGGRLQGQVRAGGRIEIGGALDWESSASVDNRPPEAFVVLERGAQLRAAGASAPLDVDGKGRTRVDSDGGQIVLRSANALYLDGAMDASAGGSGAHGGTLGVAFGGSVHARGASKEVLRARGITLSQRSPADAVLPDRLEYGHAALSVEQIQAGGFDTLSVFGDVRAEGDVDLRMGQSLRIYGQGQSSLGMAVAAPQSSGISLSAPHLLLAQSHWQSLPGENLVVTDTVASAAEGDHVLSARADLIDIRDVTWLPGFNQVVLDSRSDVRLLNAVSNGGSISALMASGSMDVSAARLYPTSGATGYLVAGASAATVATPGYWSDPDAVLRIRGTGTAATTPPESALGAMQLVAATVQQGGNVQAPMGALQLGGLVLGGTRASRVELLPGSITSTSGAGLALPYGGTVDGVSWRRGSSSLESLTPAGIASKGVTLTANDVDVHAGALLDVSGGGELTGAAFVSGRGGSVDVLRTALADANPRYAFSASGNPVYAIVPGRAGSFAPSSDDGFAAPAVGQQITVPAGVPGLPAGTYTLLPASFALQPGAFRVELGATGTSGVPQPIQTGTGTWRVSGRQGSALGGVASPLLTDILLTPAAVVRRHSGYNETSYNSFVQATADRRGEARGWQTIDALGLTLALGEGAGREGTAAIDFAGTARFSAADEKGRGGTLVATLASPAVGSLEVAAAGSPSQAHDRGATFTDDALNALRPERMVIGGQFNESASLVAVSGSVRDVAIRSGATLQAPEILVAAASGDSGILVEAGATLDTLSFARDSASAPTVPYQVNGGLLAVSNQRLNLITGTTGVAAGPVAIDIGGCQTDCEGEARLVSDGSIGVATDGVLQMRDSARYGTRQLGVSMAALNLGSAEAIAQAAAAGALPNGMTMNQSVLQQLLRGNDATGAPALDTLSLVARDSVNVFGSVDLDARDSATGRGGLQTLVLGAQAIHGYGAASDHARILVDTLVWDGSLAATQAPGSDASVPPADPMVDRLGAGQLDIVTRNLQLARAPFSRPSSEVPANRQVLGFSALNLSASEQLSFSAQGTLDVFQQRGDYLADKGWQYSGGSLGIDTPLLTADPAAQLRVRTGGDFRLQGGTGKAGGDALGSELSIDANRITLDSTIALASGRLSANAREGITLGSRAALDLAGRKVSLYDVDKFSWGGDVLLSSDTGDIRTDAASRIDVSARNNRGGRMTVTAMAGRADLAGDLQGTASGRYDAGGTLVPYDGGELVVRARQLQDFTGLNQRLTAGGVVGGRSFQIGEGDLRIGDEVKARRVDISVDAGSMTVAGRIDASGEQVGSIRLYARDQLQVDGTLDAHGTGLRVDSHGKIIDSPNRATITLGSAEGAVGLGSAAHLDMRAGSDVALGDGPGQNDGMARGSLKIDVPRLGSNDAAIAAASGLRIDGAADIQLNGVRRYDDAPLASTADVRGNRAQLVTQQWLDQVVDPHSVAWIDGALGNPDLQQRTAALGDVRLRPGVQVVARRSEANPEGDLTIAGDIDLSGYRYGPEANRADPSRRGFGESASLVLRAEGNINVHGSINDGFAPPPSTPDEGGWQLYEARNGSAGHTPFGGDLVVPVDGVKLQPGTEFQAGTRLNYDVPVESVTLPVGTVLPAPMVISQTLRLPAGTVLGAAVTTDSGQTLAAGTVLQKPLVLAAGARLGAGFRLRSAVQMAAQEWPAGAVLPVALRLAREVELKVGAYIPSLTKVELPGNGPVNLRPADANGNQGRNWALAPMLAEGTTSWDLTVVAGADSGAADPRSRRWGAEGSVVLADTHQGSIGTVKTEIIWVGDRALTERASLDWIGDTSYAGRPIAELADMYGFTEDEFCAMSADYCGPAPRQVAAQGSLDYWGDESYVGTPAKDFAAMFGMTEDEFCSTAPSYCAGGGTQTEVTTYGKRAGTPAWSVLRTGKGDLELLAAGDVVMKSGFGVYTAGTPTTLGEGRDAAFNSPRAAAPRNTALLGPNLVPGSYDAALAGYQAWYPDHGGNLRVEAGRDIVGDVWTGRAESGTSERDWALYSSAAVGNWLWRQGTGSTTGVEPVPTSWWVNFGAYTNVSAAAGASPRMVGFTGFGTLGGGNLTLEAGRDAGVRDAIGDALDSTIAPRSGAIIAAVGSTGRVSDGQLHLTGGGDLQLRIGGALNPNLRATFSSLNASRAGQNLDLNGIFSNLRGSLQLDAGRIGAMGVTLESYATLGQLRAADLFAADAARPMGGPVLVLGDAVAQLQARGDVVLGGVADAGRVPPANYSAVVQDNGSRAAGSTWFSLWTDTTAVDLFSAGGDLAPGLAGPDNVTGSNLWPEQVALAPGSREELLNYWLYPSRFSAVAAQGDVKLDRISTTPGTQDVILLAPSATGRLDVLAGGGIFAQRGATQIARSASDARLPGPFDPAFMAEQGDSSGNVTRSRHNLSVDGNIASPQASLPLFAFGPNTPLSTVSAALAPSRFYAVQGDIIGLATGAQRTLTPNGGQRTQLNWFEAAGAVQLRAGRDILGVSMTALNTAPTDITVVAAGRDIVHLNATIAGPGNTEISAGRQLRQEDAGSIVSLGGIVQGDTRPGASIALTAGNQQIDFAALRARYLDPVNLADPAQSLASQPGKAVKVYNQELKQWLQQRFGVAADGDGALAAFDALPQEQQRIFLRQVYYAELREGGREYTDAEGPRFGSYLRGREAIATLMPDRNAAGATIDRTGDIVMYGGSGVRTEAGGNVELMAPGGQIVVGVQGVVPPASAGLVTQGQGDIRLFSQDSVLLGLSRVMTTFGGDILAWSEQGDINAGRGSQTTLLYTPPRRLYDGWGNVILSPQAPASGAGIATLNPIAEVPPGDVDLIAPLGTIDAGEAGIRVSGNINLAALQVLNAANIQVQGESKGLPVLATVNVNALASASAAANSASQAAQDVMRKSQDDARRNQPSVISVQILGFGSGTSSIAPPARGTTADSGYDANSAFQFPQASRDEGTQRR
>NZ_CP015612.1|WP_088026179.1|2528967_2530143_-|alkaline-phosphatase
MTKYKTLAALVATVLLATVGAASAQTVTGGGASLPADLYKGSADSILPANFSYAVTGSGTGKKAFLENNSALFSTTGTVHFAGSDSVLSSAELSTYTTNFNQPTNANRYGALIQVPSVATSVTIPFNKAGSAVDLSVAQICGVFSGAISDWSTIDTDRSGPIQVVYRPESSGTSEILTRFLATNCARERAETSNLVGGTFAIKSTFADLYKRDANGSLPGFLVAAPATGDTSLYNAVYAFEGRIGYAGPDVIPSLTDATKVAKVRGFSPDRAQWEFILTVFDPPSGIAAQNPANWAPYMGNPSVIYPIIGYTYLLIGQCYKDQTVANKLRGFLARHYSAAYPAAYEASITGHGFAPLPKMWRDAIRNRFVLASSTAGLNNPSTCSGIGRPL
>NZ_CP015612.1|WP_049463074.1|2530543_2531719_-|alkaline-phosphatase
MTKYKTLAALVATALLATVGAASAQTVTGGGASLPADLYKGQADSILPANFSYAVTGSGTGKKAFLENNSALFSTTGTVHFAGSDSVLSATELSTYTTNYNQSTNANRYGALIQVPSVATSVTIPFNKPGSAVNLSVAQICGVFSGAISDWSTIDANRSGPIRVVYRTESSGTSEMFTRFLAAACAAEPAATSNLVGGTFAVKSTFADLYKRDANNNLPAFLVAAPATGGTSLYNAVYAADGRIGYVGPDVIPSLTDATKVAKVKGFSPDQVSVQATLDTVAPPTGTAAENPANWVPVFGNPSAGYPIAGYTNLVIGQCYKDSAVATSLRGFLARHYPATYPAAYEASITGHGFIPLTKAWRDAIRNRFVLASSAAGLNNPSTCSGIGRPL
>NZ_CP015612.1|WP_088026180.1|2532031_2533231_-|type-II-secretion-system-inner-membrane-protein-GspF
MALFDYQAANAQGRIEKGQLDADSPRGARQLLRGRGLTPVQVSAARSAGSGWGARRLSASELAWATRQLASLLAASLPLEGALSAVIEQAERPHVAQALTAVRADVRAGQRLTVALAARPRDFPPIYRALVGAGEDSGDLARVMERLADYIEERNALQAKVLTAFIYPAAISLVSVAIVIFLLSYVVPQVVTAFVQARQTLPMLTQVMLAASAFVRSWGAWVGLGIAALVVVWRLALRKPELRLRWDAMLLRLPMVGRFVLGVNSARFASTLAILLDAGVPLLRALEAARQTLGNALLARCADDVSARVREGAALGAALKVQKVYPPILVHLVASGEKTGSLAPLLDRAAQTISREIERRAMALTALLEPTMILVMGGVVLTIVLAVLMPIMEMNQLVQ
>NZ_CP015612.1|WP_088026181.1|2533238_2534672_-|type-II-secretion-system-ATPase-GspE
MSAPAPLPYAWVRSHGVMLSEAGGEPVLLGTADTAAWAVAELRRRHGPLPFHALDAATWQQRLGEQYRDGGDAAAVVGAAESEVDLDRLMQDMPEVTDLLDAQDDAPVIRMINALLAQAARDGASDLHIEPFETHSVVRYRVDGTLRDMVQPRRALHAALVSRIKIMAHLDIAEKRLPQDGRIAIRVGGRPLDIRVSTVPTGHGERAVLRLLEKDAGRLQLQRLGMADDTLATFTGLIRQPHGIVLVTGPTGSGKTTSLYAALGQLDSSTSNILTVEDPVEYDFAGIGQIQVNARIGMSFGTALRAILRQDPDTIMIGEIRDLETAQIAVQSSLTGHAVLASLHTNDAISAVTRLADMGVEPFLLASSLRGVLAQRLVRRLCRQCRRAEVDGEGRTVWRAVGCAACANSGYRGRTGIHELFVVDDRVRALIHEGQGEPALREAARRAGMRTLRQDGQRWVDSGVTTLEEILRVTGDD
>NZ_CP015612.1|WP_088026182.1|2534668_2537050_-|type-II-secretion-system-secretin-GspD
MRAMRSLACSTALALIVGMAHVPTPVAAQDTRDEPVQLNLVDTDIGGVLRMAARFTGRQFLVDPRVTGKMTVVSDGPVSRSQAYQLLLGALRMRGFAVVENGGVSRVVPQAEAKLLGGRVGTGGAGGEVATRTFALRYENAAALVAVLRPMISPDNPITANPGNNTLVITDYADNLERIARVIASVDTPAGMDTDVVKLQQGIAVDVAEMVAPLLDAQGAEPSQKVVVMADPRSNSVLLRSSSPGRTRLARQLVEKLDRAQDESGNLHVVYLRNAQANQLAGVLRGVVAGQSDAPAMGSNEGITPLPGDANRPTPTQPSQPQQAKTGGNALESQRLDPSRRDPIDAGSTGFSQNGISVQADVATNTLLISAPEPVYRNLRRVIDQLDQRRAQVLVESLIVEVNQTDAAELGVQWMLGNGRTFGGTHFGGVTGGSGLNTAARTTLDVLPKDGLKIGVIDGTINLPGVGQILNMKALANALQSKGGANILSTPNLMTLDNEAASIMVGQTVPFVSGRYVTDGGGGSNNPFQTIVREDVGLKLRVRPQISEGGTVKLDIYQEVSSIDAQSANSAAGIITNKRALDTSVLLDDGQIMVLGGLLEDNVSHGRDAVPGLGKLPLLGALFRSDTRKRSKTNLMVFLRPHVVRDPAAGQRLTRDRYDYMRNAQASAQPVQSWALPALSAPQLPPQDLSVLGQGNARDGQGQPLQNTSLAALYPAGEGDAQLVQFAQGLDPARASQGVAQVQALGLQAYAEAAPGESGQRLRVRLPRDPATLDPALQQLRGLGYTPELVIGP
>NZ_CP015612.1|WP_088026183.1|2537046_2537574_-|general-secretion-pathway-protein-GspM
MTTRTLRLGGELAGLQQRWQRLPPRDRLMLWVMVVALLAAGLWMLWLEPLLKQHAHWQAELPRLQAQSRALAPLLRARERQQQAQGEHPTLASLRDGIRSAGLADGLHIEARDGRWHLQVQAVPADALWNWLLPLLADPAIELQQLQLTRTGDANMPAARISGNIVMVATAGAHP
>NZ_CP015612.1|WP_088026184.1|2537570_2538734_-|general-secretion-pathway-protein-GspL
MNVQLRVRLPALERLRADSAVEWAQLHKGEVLAHGCDTLAALGLRHPQAAVHACLDPNDLILLELQLPPLSGRRLQSALQGEVEAMLLDDLQEVALAHGAQAADGTVPVAWLGQQALLQAQQLLASCALRLQALYPTPLLLPWQDGHATLQVSGEHLMVRSGRDRGFIQWYGGRDACAVMQTLAVRLQQAGVQAVQWIDGVPPTWPDSLPATAVTHERQASGPLPGWSLPLPGAGQKAPRLAIGLALTAMLLTALGLQLQVSRWRSEGEALQQDMTRKFSARFPEITDVVDPVLQARRALAVPLPAPPLPPLQRQVAGTLQAVPELAGQVRSLHYQPGQLEMELDADARALADDPQRLEHWQQAVQAQGLQLAREAGGRLRVSGAGQ
>NZ_CP015612.1|WP_088028368.1|2538730_2539636_-|type-II-secretion-system-minor-pseudopilin-GspK
MTARTRSVPCARQRGMAVIVALLVVALVAVIATALLTRQSAQLRALRGDQLRAQVRMAVDATLERAAQQLREDVKEQLTTVRSGRWAHPLELQAPLPVQLQLVDAQSMFNLRNLLAHGRPDPESRRAFIALCAGQGLGQGACASAADHIQARLRDGDLQAQAPLPRESLIAQALPGADAVALQALERRTVVLPAQTLVNANTCDLRVLQAVTPAVEPARLQALLGERDAGHWLLNRGDIANRLQLSNEQMAVLPLGIHSEWFLAVGQVQADGSGVDFRALLWREYRDDGVRVQRVWTRIGA
>NZ_CP015612.1|WP_088026185.1|2539645_2540083_-|type-II-secretion-system-major-pseudopilin-GspG
MARQVRGRRARQQGFSLIEIMVVVVIIGILAALIVPRLMDRPDQARVVAARQDIAALMQALKLFKLDNGRYPSAEQGLQALVKPPQGSGAMPITLYLDRLPNDPWGHPYQYQIPGTHGDIDVFSLGADSKPGGDAGNADIGSWQL

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Crispr_ID: NZ_CP015612_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_7

3822686-3822796

Orphan

Consensus_repeat	Method
GCATCAGTGCCAACCAAGGTTGGCACCCACCAGGCCCACCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_7

>merge|NZ_CP015612|7|3822686-3822796|CRISPRCasFinder
GCATCAGTGCCAACCAAGGTTGGCACCCACCAGGCCCACCGCAGTAGATCCACGCCATGCGTGGATGCACGCATCAGTGCCAACCAAGGTTGGCACCCACCAAGCCCACCG

>NZ_CP015612|7|7|3822686-3822796|CRISPRCasFinder
GCATCAGTGCCAACCAAGGTTGGCACCCACCAGGCCCACCG	CAGTAGATCCACGCCATGCGTGGATGCAC
GCATCAGTGCCAACCAAGGTTGGCACCCACCAAGCCCACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088027040.1\|3817652_3819071_+\|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl\|CDD\|235490
NZ_CP015612.1\|WP_088027043.1\|3820864_3821638_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183716
NZ_CP015612.1\|WP_088027041.1\|3819070_3819649_+\|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl\|CDD\|179314
NZ_CP015612.1\|WP_049421767.1\|3828072_3828720_+\|protein-L-isoaspartate-O-methyltransferase	unknown	unknown	gnl\|CDD\|225316
NZ_CP015612.1\|WP_088027053.1\|3834502_3835834_-\|O-antigen-ligase-family-protein	unknown	unknown	gnl\|CDD\|225844
NZ_CP015612.1\|WP_088027038.1\|3815215_3816802_+\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|234864
NZ_CP015612.1\|WP_088027042.1\|3819638_3820700_+\|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl\|CDD\|234832
NZ_CP015612.1\|WP_088027039.1\|3816812_3817592_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP015612.1\|WP_088027037.1\|3814127_3815219_+\|threonine-dehydratase	unknown	unknown	gnl\|CDD\|236339
NZ_CP015612.1\|WP_088027052.1\|3833915_3834365_-\|transposase	unknown	unknown	gnl\|CDD\|376616
NZ_CP015612.1\|WP_088027045.1\|3822840_3826002_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP015612.1\|WP_088027049.1\|3830163_3831381_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|129987
NZ_CP015612.1\|WP_014038403.1\|3813779_3814031_+\|acetolactate-synthase	unknown	unknown	gnl\|CDD\|226486
NZ_CP015612.1\|WP_088027050.1\|3831596_3832895_-\|3-deoxy-D-manno-octulosonic-acid-transferase	unknown	unknown	gnl\|CDD\|235589
NZ_CP015612.1\|WP_088027036.1\|3812059_3813796_+\|acetolactate-synthase-2-catalytic-subunit	unknown	unknown	gnl\|CDD\|181601
NZ_CP015612.1\|WP_088027051.1\|3832955_3833873_+\|LpxL/LpxP-family-Kdo(2)-lipid-IV(A)-lauroyl/palmitoleoyl-acyltransferase	unknown	unknown	gnl\|CDD\|181542
NZ_CP015612.1\|WP_088027044.1\|3821756_3822662_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176161
NZ_CP015612.1\|WP_088027047.1\|3827255_3827936_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379522
NZ_CP015612.1\|WP_088027046.1\|3826006_3827137_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP015612.1\|WP_088027048.1\|3828736_3830095_+\|TolC-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|273829

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088027040.1\|3817652_3819071_+\|3-isopropylmalate-dehydratase-large-subunit	gnl\|CDD\|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_CP015612.1\|WP_088027043.1\|3820864_3821638_-\|SDR-family-oxidoreductase	gnl\|CDD\|183716	PRK12744, PRK12744, SDR family oxidoreductase.	6.83272e-177
NZ_CP015612.1\|WP_088027041.1\|3819070_3819649_+\|3-isopropylmalate-dehydratase-small-subunit	gnl\|CDD\|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	6.40235e-93
NZ_CP015612.1\|WP_049421767.1\|3828072_3828720_+\|protein-L-isoaspartate-O-methyltransferase	gnl\|CDD\|225316	COG2518, Pcm, Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones].	6.71569e-65
NZ_CP015612.1\|WP_088027053.1\|3834502_3835834_-\|O-antigen-ligase-family-protein	gnl\|CDD\|225844	COG3307, RfaL, Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane].	1.49111e-17
NZ_CP015612.1\|WP_088027038.1\|3815215_3816802_+\|2-isopropylmalate-synthase	gnl\|CDD\|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NZ_CP015612.1\|WP_088027042.1\|3819638_3820700_+\|3-isopropylmalate-dehydrogenase	gnl\|CDD\|234832	PRK00772, PRK00772, 3-isopropylmalate dehydrogenase; Provisional.	0
NZ_CP015612.1\|WP_088027039.1\|3816812_3817592_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.3183e-22
NZ_CP015612.1\|WP_088027037.1\|3814127_3815219_+\|threonine-dehydratase	gnl\|CDD\|236339	PRK08813, PRK08813, threonine dehydratase; Provisional.	0
NZ_CP015612.1\|WP_088027052.1\|3833915_3834365_-\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.3876e-09
NZ_CP015612.1\|WP_088027045.1\|3822840_3826002_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP015612.1\|WP_088027049.1\|3830163_3831381_-\|amino-acid-transporter	gnl\|CDD\|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.33689e-08
NZ_CP015612.1\|WP_014038403.1\|3813779_3814031_+\|acetolactate-synthase	gnl\|CDD\|226486	COG3978, COG3978, Acetolactate synthase (isozyme II), small (regulatory) subunit [Function unknown].	2.29252e-22
NZ_CP015612.1\|WP_088027050.1\|3831596_3832895_-\|3-deoxy-D-manno-octulosonic-acid-transferase	gnl\|CDD\|235589	PRK05749, PRK05749, 3-deoxy-D-manno-octulosonic-acid transferase; Reviewed.	0
NZ_CP015612.1\|WP_088027036.1\|3812059_3813796_+\|acetolactate-synthase-2-catalytic-subunit	gnl\|CDD\|181601	PRK08978, PRK08978, acetolactate synthase 2 catalytic subunit; Reviewed.	0
NZ_CP015612.1\|WP_088027051.1\|3832955_3833873_+\|LpxL/LpxP-family-Kdo(2)-lipid-IV(A)-lauroyl/palmitoleoyl-acyltransferase	gnl\|CDD\|181542	PRK08733, PRK08733, LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase.	0
NZ_CP015612.1\|WP_088027044.1\|3821756_3822662_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176161	cd08472, PBP2_CrgA_like_3, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 3. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.58829e-98
NZ_CP015612.1\|WP_088027047.1\|3827255_3827936_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379522	pfam14246, TetR_C_7, AefR-like transcriptional repressor, C-terminal region. This family comprises the C-terminal domain of transcriptional regulators of the TetR family. It includes the AefR transcriptional regulator from P. syringae. It is found in association with pfam00440.	4.31774e-26
NZ_CP015612.1\|WP_088027046.1\|3826006_3827137_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	2.20909e-60
NZ_CP015612.1\|WP_088027048.1\|3828736_3830095_+\|TolC-family-outer-membrane-protein	gnl\|CDD\|273829	TIGR01844, Proteases_secretion_protein_PrtF, type I secretion outer membrane protein, TolC family. Members of this model are outer membrane proteins from the TolC subfamily within the RND (Resistance-Nodulation-cell Division) efflux systems. These proteins, unlike the NodT subfamily, appear not to be lipoproteins. All are believed to participate in type I protein secretion, an ABC transporter system for protein secretion without cleavage of a signal sequence, although they may, like TolC, participate also in the efflux of smaller molecules as well. This family includes the well-documented examples TolC (E. coli), PrtF (Erwinia), and AprF (Pseudomonas aeruginosa). [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Porins].	1.99448e-107

>NZ_CP015612.1|WP_088027044.1|3821756_3822662_+|LysR-family-transcriptional-regulator
MDRIDRFRIFTRVVECASFTRAADQLGLPRSTVSAAIAELEQRLGTRLLQRSTRRVSTTHDGDVFHARCLRLIEEVEDAESLFRQDDAQPVGLLKIDVPSRIGRRIIAPALPDFFARHPQVEVDLGMTDRAVNLIEDGCDAVLRVGQLGDSSLVARTLGQLDFVNVAAPAYLREHGVPQHPADLQQHRAVNYASPTTARVEPWEWQDGGQLRTLPMPGWVRVNSAEASIACCVAGLGLLQIPRYDVQAELQSGALVEVMPQYVAQPLPVTLLQPHRQHRALRVQVFIEWLLPVLRSGLQLQ
>NZ_CP015612.1|WP_088027043.1|3820864_3821638_-|SDR-family-oxidoreductase
MTDHSLKGKTVLIAGGAKNLGGLIARDFAAQGAKAIVIHYNSAATQADAEATVAAVQAAGSKAVALQGDLTSAAAMERLFADAVAAVGRPDIAINTVGKVLKKPMLEISEAEYDEMSAVNAKTAFFFLKEAGRHVNDGGRICTLVTSLLGAYTPFYSSYAGTKAPVEHFTRAASKEFGERGISVTAIGPGPMDTPFFYPAESADAQAYHKTAAALSAFTRTGLTDIADIVPWIRFLVTDGWWMTGQTILVNGGYTTK
>NZ_CP015612.1|WP_088027042.1|3819638_3820700_+|3-isopropylmalate-dehydrogenase
MHTEIVVLPGDGIGPEVAAAAVAVLKAVAERFNHTFTFSEHDIGGVAIDRHGEPLPASTLEACKAANAVLLGAVGGPKWSDPNAKVRPEQGLLAIRKALGLYANLRPVRTHEAALHASPIKAELLQGVDFVVVRELTGGIYFGDKTRDADSASDLCRYTVAEIERVLRSAFRLAQQRRGKVTSVDKANVLETSRLWRDVAARIGREEFPEVALEHQLVDSMAMHLLAKPREYDVIVTENMFGDILTDEASMLAGSLGLLPSASLGEPGTVGIYEPIHGSAPDIAGKGIANPYATIFSAAMLLRHSLGLEAEAAAVEAAVHAVLDDGVFTADLAAKGQAVSTAAATDAVLAKLN
>NZ_CP015612.1|WP_088027041.1|3819070_3819649_+|3-isopropylmalate-dehydratase-small-subunit
MAGFRTLTSSSVVLAQTNIDTDQIIPARFLSTTERAGLGRNAFNDWRWQADGSPVADFAFNQPHNAGRSILLAGRNFGCGSSREHAPWALTDLGLRAIVSSEIADIFRGNSLKNGLLPIVLDEADVQALMQRPDDELTIDVAARELRTPDGRVYSFPLDGFSQTCLLEGVDQLGYLLGRVPEIERYESEHAH
>NZ_CP015612.1|WP_088027040.1|3817652_3819071_+|3-isopropylmalate-dehydratase-large-subunit
MTSAPRTLYDKLWDAHVVVPESDSAPAVLYIDLHLIHEVTSPQAFTELRERGLSPRRPDRTKATMDHSTPTLPAAADGTLPYASAASEAQVATLARNCAEHGIELFDMASDNRGIVHVIAPEQGFTQPGMTIVCGDSHTSTHGAFGSLAFGIGTSEVGHVLATQCLLQRKAKTFAITVDGPLAPGVGAKDVVLHIIGVIGVNGGTGHVIEFRGSTIEAMDMEQRMTLCNMSIEAGARAGMVAPDQVTFDFVAATPRGPKGADFDAAVTRWQQLRSDEGARFDSEVHIDAADIRPTLTWGTHPGTAIAVDAPIPAANDAAAQKGLDYMHFQAGKALAGTPVDVVFVGSCTNGRLSDMREVAQVLRGRRVAERVRMLVVPGSEIVKREAEAEGIHEIVRAAGAEWREPGCSMCIAMNGDLVAPGQLAVSTSNRNFEGRQGPGSRTLLASPMSAAWAAVNGHVADTRELFAQEVA
>NZ_CP015612.1|WP_088027039.1|3816812_3817592_+|class-I-SAM-dependent-methyltransferase
MSAFDTPTPASAAGQQWNAQDYAIDAGFVPLLGGAVSRLLDPRAGERILDLGCGDGVLSTELALSGAHIHGVDASPELVIAARARGVDAQVMDGHALSFDSEFDAVFSNAALHWMGNPDRVMEGVRRALRPGGRFVAEFGGHGNVATIIAAVQAARVAHGHGASAFQWYFPTADAYADRLRQHGFQVQLIECTPRPTALPTGVAGWLRVFAAPLLDDLPAEARATVREAATALLAELPRNAAGQPLADYVRLRVLARRR
>NZ_CP015612.1|WP_088027038.1|3815215_3816802_+|2-isopropylmalate-synthase
MTTIERITTPRIRIFDTTLRDGEQSPGCSMSPPQKLVMARALDELGVDIIETGFPASSQSDREAMALIGRELRRPSLALAVLSRCLQADIETSARALEAAANPRLHVFLSTSPLHREHKLRMTREQVLESVRKHVSLARSYIDDVEFSAEDATRTELDYLIEVARVAIAAGATTINLPDTVGFTTPEEIRAMFQQVIAGVADVPNAANVIFSAHCHNDLGLAVANSLAAIEGGARQVECTINGIGERAGNCSLEEIAMVLKVRQAFYEQDSSINTPRIVGTSQLLQRLVGMPVQRNKAIVGANAFAHESGIHQHGMLRHRGTYEIMRPEDVGWEDSQMVLGRHSGRAAVEARLRALGFWLDEDELKLVFEQFKGLCEQQRVVTDADLQTLMQGGSNAQGYRLASMTISDVGSRANALVELSDPDGNRVAETAQGDGPVDALFGALSAATGVQLMLDSYHVHSVGIGADARGEANLSVRHEGVEYDGTGTSKDIIEASALAWLDVANRLLRQRQAAAHSSTDVATPATA
>NZ_CP015612.1|WP_088027037.1|3814127_3815219_+|threonine-dehydratase
MPAADTSQESDVGDVSVADVLAAQARLRRFLPPTPLHHAERFGTWLKLENLQRTGSYKVRGALNALLAGRERGDTRPVICASAGNHAQGVAWAAYRLDVPAITVMPHGAPATKIAGVAHWGATVRQHGTSYDEAYAFAVELAQRHGYRFLSAFDDADVIAGQGTVGIELAAHAPDVVIVPIGGGGLASGVALALKSQGVRVVGAQVEGVDSMARAIRGDVREIAPVASLADGVRVKIPGFLTRRLCTSLLDDVVIVREAELRETLVRLALEEHIIAEGAGALALAAGRRVAGRRKCAVVSGGNIDAGVLAGLLTDIRPRPPRKPRRRRSESPRSPSKASATASHTSSPSPLQAVTPAVEEISL
>NZ_CP015612.1|WP_014038403.1|3813779_3814031_+|acetolactate-synthase
MQYRLDLVLHPAEGALLRVIGMAERRGFAPRAISGAPVAADDGRWHLQLVVDGQRPAETLCRQIEKIYDCVSVQVTAVEGASV
>NZ_CP015612.1|WP_088027036.1|3812059_3813796_+|acetolactate-synthase-2-catalytic-subunit
MNSSTHRSAPPNGARWLTQALEAEGVRTLFGYPGGTIMPFYDALVDSSLKHILVRHEQGAALAANGFARASNQVGVCVATSGPGASNLVTGIADAMLDSVPMVCITGQVGTPLLGTDAFQELDVFGLTMPIVKHSWLVRSVDDLPRVVADAFRIAREGRPGPVLIDLPKDVQLADASHLPAHAPSSVEPPPAPAEAAIAEAIAALAAAEKPVVYAGGGIALGDAVQDLRDFVEASAIPTVMTLRGLGALPASHPQSLGMLGMHGTRAANMAVQESDLLLVLGARFDDRATGKLAEFAPFARVVHIDADAYEISKLRSADVAVPGNVGHAIRALRAAFPSPKAHQDAWRKRCAQHRDRFAARYDAPGQHIYAPALLKRLSELAPADAVIACDVGQHQMWVAQHCRFNHPRNHLTSGALGTMGFGLPAAMGAQFACPDRTVVLVSGDGSFMMNVQELATIARCRLPVKIVLLDNSSLGMVRQWQELFFAERYSEIDLSDNPDFVALAQVFGIAATRIDNRDDVEGGLAALLAEPGPALLHVAIDARANVWPLVPPNTANSTMLESNPAHARQETPNAIPA
>NZ_CP015612.1|WP_088027045.1|3822840_3826002_-|efflux-RND-transporter-permease-subunit
MRRFNLSEWALANRPLVLFAMLAFALIGAWSYKHLGQSEDPPFTFKAMVVRTLWPGATAEQVSRQVTEPLEKALMNTGEYEFIRSYSRPGESQIIFMARDSLRSKQIPDLWYQVRKRVGDIRPTLPREIVGPFFNDEFGDTYGNIYALTGKGFDYAVMRDYADRIQLELQRVPDVGKIDLVGLQDEKVWIELSNTRLATLGVSMQQVQQALADQNAVTGTSFFETATDRVQLRVTGQFNDIDAIRQFPIRAGDRTVHLGDIAEVKRGFADPASPKMRFMGEEAIGLAVAMKDGGDILKLGANLDAEFERLQKTLPAGMQLRKVSDQPQSVEESVGEFVQVLTEAVVIVLLVSFFSLGLRTGLVVGVTIPLVLAMTFFVMHYFDIGLHKISLGALVLALGLLVDDAIIAVEMMATKMEQGYDRLRAASFAWESTAFPMLTGTLITAAGFLPIATAASSTGEYTRSLFQVVTIALVVSWIAAVLFIPYLGDKMLPDLFNPQPPKPGSLSARWLAKRQQWADRYPALANLIAPPQHGHDHDPYQRPFYRSFRRFLDGCLRHRWWVIAATIALFVFSLMMFRFVPQQFFPDSTRPELMVDIELAEGASLRSTQAQAEKLEKLLSNREGIANYVSYVGTGSPRFYLPLDQQLPATNFAQFVVLAKDIKSRESTRDWLLHEVIQKFPDVQMRVTRLENGPPVGYPVQMRISGEHIEKVQAIARQVEAKVRENPHVMNVNLDWSEPSKVVRLVIDQERARALGVSSAQVSQFLSSSLAGQSVSVYREGNRQIEMLLRGPADERNQLELLSSLSMPTANGGSITLSQVATMEYGFEDGIIWHRNRLPTVTVRADISDGMQPLDVVHQILPTLDGIRAELPSGYLLETGGTVEDSARGQNSIKAGMPLFLVVVATLLMLQLRSFSRAAMVLVTAPLGIIGATLFLLLFRAPFGFVALLGTIALAGMIMRNSVILIDQIQQDIDAGHDRWHSIIDATVRRFRPIVLTALAAVLAMIPLSRSAFYGSMAISIMGGLIVGTVLTLVFLPALYAAWFRVKPDESGA
>NZ_CP015612.1|WP_088027046.1|3826006_3827137_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MKIVRWMGGMVWVAALAACSGQEQAPQAAVPVLVVHPGEQAGQAPAAFPGTVRARQESPLSFRVGGNLVKRHVDAGQRVKKGDVLAELDAADFALQARASQAQLAAAEADLVRARDDLKRYQVLADQQLVSRSQLDQQSAAFKAAQGQANAARANLDVLRNQADYAQLRAPADGVIASREAEAGQVVSAGQTIFNLAADGGREVLIDLPEATIRDYAVGQPVEVELWNRPGQRLPGTIREIAAAADPQARTYATRVSLAADALADVELGQSARVYSSAGRHGTLQLPLGALQRGANGAASVWVVDPANSTLKAAVVTTGAFGSESVPVLSGVNAGDWVVAAGGHLLRAGQPVIAVDRQNRPVLKPAAPAAAAKAKE
>NZ_CP015612.1|WP_088027047.1|3827255_3827936_+|TetR/AcrR-family-transcriptional-regulator
MSSPTSRKPSAKPAAKAAGPGRPKDLGKRAAILEAAKALFIEQGYTGVSMDTIAAQAGVSKLTVYSHFGDKETLFSEAVQSKCIEMLPDALFVTDADGPLRDQLIGIGLAFFELITSDAAISIQRMMMAPETDERLRELFWQAGPERTCEALADFLRARGERGELDIPDYYLAGQQFLTLVKGEVHMHMMCGMPLSPVECDPLAHVTASIDFFLRAYAPRGAGTAE
>NZ_CP015612.1|WP_049421767.1|3828072_3828720_+|protein-L-isoaspartate-O-methyltransferase
MTIDYAHARELMVEQQIRPWDVLDIKVLDVLARLPREAFVADAHRALAYADVELPIGHGQKMMKPVIEGRTLQALDLQPGDEVLEIGTGSGFLAACIGALARDVLSLEIDPELAAAARARLDASGLGTNVRVEVADALSWQTERRFDVICVTGAVDVVPSQFASWLRPGGRLFVIHGRSPAMEALLVKADGSSESLFETDIDYLRGAAPAPQFHL
>NZ_CP015612.1|WP_088027048.1|3828736_3830095_+|TolC-family-outer-membrane-protein
MIRRSLAVALATALLPLSAHAADLLQVYEMARNGDPQLSAAESTRLYDKEGAVQARAALLPQIDGTATLNRSRSEADHDANSGTVTSKRRNYTINGSQTLFNWTQINNLRSQRELSKAADFTLDSANDSLIVRTSAAYFNVLVAIESLNAAQTNEAAAKKQFDFADKRLEVGLAPITDVHEARAQYDQARANTIVAQNTLADNYQALTELTGQPVVNLRGLPADFRPEVPANRGNIDELVHQATNQNPALKAQELKVSAAEAGVQAARGGHYPTLSLGGSWGKTATWGDSTGAGSLSPDARTNSIGLTLSVPIFSGGATQSGVRQALAQRDIAQDGYEQQKRALDRNTRNAYQTLVQGISEVEARRLAVVSAQSAYDASQVGLEVGTRTVLDVIQNQRILFSAQLDYAQARYTFLQNRLLLSQSLGALDVAELQDVNRLLTQDAGNPATTTH
>NZ_CP015612.1|WP_088027049.1|3830163_3831381_-|amino-acid-transporter
MDSDNSCDRDACLGRDHVATVALTLLLGGSVIALVGQHTAAQAGPAIVLSLLLAALGTMPLLYCLHVLNQQLPVAGLQGLLRAGWGRASGGLLGGMLLLELVATSAGAAQSMASHLRVFLLRCGIDAGNAMPDQLAAVFGLLLLGVVGLLPPRRAVLVACALLTMKIGIGLLLLALAARYVHYALWIPWLPEATAPYRFGLGGVLAASVPLLGVFASVGLALGFPGIGRQENARQPLLLAGMLLLAMLLLIVLAALQAGLVEFPALASTRPLSVALQQHPQLHWMMPLLPLAGAAGLAALLLVLMGAAARLAMQLWPAARHAAPGLRARLAYGAVVLSAAMLALVLPVGALPVLPGPATLLVMAALCLAVLRVQVPPSPVLPVLAPVAAALCMLAAVERMRVWPG
>NZ_CP015612.1|WP_088027050.1|3831596_3832895_-|3-deoxy-D-manno-octulosonic-acid-transferase
MRKDPVEWILRGLYSVVLYILLPITVYHLVWRGFRVREYFRRWDERYASYPQPTGQPRVWLHAVSVGEVNAAAPLVNALREQRPDIRWVITTITPTGSERVRALWGDALDHVYLPYDVPGSVNRFLGHFQPSLALILETELWPNMLFGCRDRGIPVYILNARLSARSLRGYRLLAALIRRALRTVTCVAAQSQDDADRFVQLGAAPEQVQALGNLKFDITTPDVQGFVEQFHARVPAGRPVWIAASTHDGEEQAVVDLHRRLRQQHPDLLLLWAPRHPERFPKVEALAREQGWNVATRRAKQWPEADTDVFVIDTLGELMPFYACAQVAFVGGSLQPIGGHNLLEPAAMGTAAVTGPHLHNFAEISRRMREAGALLIGEDVQAVGDLLQHLLDDVQARLDMARAGCTLVSNGRGALQRTLALVAPHLPPPRS
>NZ_CP015612.1|WP_088027051.1|3832955_3833873_+|LpxL/LpxP-family-Kdo(2)-lipid-IV(A)-lauroyl/palmitoleoyl-acyltransferase
MSDATTAVRPSLRDPRNWPMFAAMFGAFAIARLPWMLQRALGRGVGWITWRLLGSRRRAAEVNLQLCFPEKDEGWRQRLVRDSFDALGVGVFECIRAWWGSIDRIRPQVQIEGLEHLRQMQAEGRGVLLVSGHFMTLEMCGRLLCDYVDLSGMYRKHKNPVYEWAVKFGRLRYAKAMFANEDIRATVRHLKKGGFLWYAPDQDMRGKDTVFVPFFGHTASTITATHQLARMTGCAVIPYFHRREGGRYFLKIGAPLENFPSEDVEADTTRVNQAIEEMVREAPDQYLWIHRRFKRQPGGRSDFYK
>NZ_CP015612.1|WP_088027052.1|3833915_3834365_-|transposase
MASPRLRYGRFSRSGNVYSLTTATLGREALFADAANVAILIDTLRFVERKGFSHSLAWVVMPDHLHWLMELRSETLAECMALLKSRSSRLLNRRLERRGSLWQHGYHDHAVRSDESLHEKAMYILANPVRAGLVSALGEYPHAWCRWPL
>NZ_CP015612.1|WP_088027053.1|3834502_3835834_-|O-antigen-ligase-family-protein
MPTSPADPATLVRDDRAGRWAPWWVLAYVALWPLPGIAETVLGLGAVYAAARMVMRRLQRRPHLLSTAAWALTSILFLGYWLPQAFSAFDAIDPAASWTKAAAGLRYLPFMWLVAIAVATPERRRLTFGGLAVITAAWTLDALVQAVVGTSPWFWSLEQLKLAVSGHALCPADEAAVADRLSGALGPCNLKFGQVLASLSPFLLLPVARRFGNAGWVLAAAALGSVLLLAGSRASWITFALVLAYSGVRQFGWKRLAVLALVAVLGAGVLTASVPQLRERFARTAMAWDGGERGVDEALSGRARIWEAAVCMIEAHPVNGVGARGFRDAYPACVADEGPAVWGNAPALHAHQIVLEVLAETGVLGLLLWLAAVAQAWRAWRYAPAAARERARPAMLALAVTVFPLNTHLAFYSAFWGGLTVLLAALFAGSLLARESDESAPVR

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Crispr_ID: NZ_CP015612_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_8

3951328-3951438

Orphan

Consensus_repeat	Method
GGCAAAGGCGTGCGGGCCAACGGTCCGCACCCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_8

>merge|NZ_CP015612|8|3951328-3951438|CRISPRCasFinder
GGCAAAGGCGTGCGGGCCAACGGTCCGCACCCACCATGCTGGTGGTGGCATTCATTGGCAGCGCCGGGCCGTGCTTGGCAAAGGCGTGCGGACCAACGGTCCGCACCCACC

>NZ_CP015612|8|8|3951328-3951438|CRISPRCasFinder
GGCAAAGGCGTGCGGGCCAACGGTCCGCACCCACC	ATGCTGGTGGTGGCATTCATTGGCAGCGCCGGGCCGTGCTT
GGCAAAGGCGTGCGGACCAACGGTCCGCACCCACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_005411067.1\|3953165_3953444_-\|YbeD-family-protein	unknown	unknown	gnl\|CDD\|179161
NZ_CP015612.1\|WP_088028491.1\|3946912_3948151_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027171.1\|3944639_3945683_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|183212
NZ_CP015612.1\|WP_005411057.1\|3941661_3942102_-\|response-regulator	unknown	unknown	gnl\|CDD\|381108
NZ_CP015612.1\|WP_088027182.1\|3952467_3953178_-\|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl\|CDD\|237681
NZ_CP015612.1\|WP_049447834.1\|3956110_3957331_-\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NZ_CP015612.1\|WP_088027185.1\|3957431_3958706_-\|septal-ring-lytic-transglycosylase-RlpA-family-protein	unknown	unknown	gnl\|CDD\|223868
NZ_CP015612.1\|WP_088027164.1\|3939327_3940071_+\|20S-proteasome-subunit-A/B	unknown	unknown	gnl\|CDD\|239734
NZ_CP015612.1\|WP_088027166.1\|3940145_3941657_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|237526
NZ_CP015612.1\|WP_088026673.1\|3962424_3963387_+\|transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP015612.1\|WP_088027175.1\|3948168_3948759_-\|DUF2242-domain-containing-protein	unknown	unknown	gnl\|CDD\|378349
NZ_CP015612.1\|WP_049447832.1\|3953613_3954606_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|367655
NZ_CP015612.1\|WP_088027189.1\|3963466_3964579_-\|rod-shape-determining-protein-RodA	unknown	unknown	gnl\|CDD\|274033
NZ_CP015612.1\|WP_088027169.1\|3944085_3944469_-\|BON-domain-containing-protein	unknown	unknown	gnl\|CDD\|225379
NZ_CP015612.1\|WP_088027187.1\|3958702_3959848_-\|lytic-murein-transglycosylase-B	unknown	unknown	gnl\|CDD\|274066
NZ_CP015612.1\|WP_088027177.1\|3949004_3951182_-\|tail-specific-protease	unknown	unknown	gnl\|CDD\|236873
NZ_CP015612.1\|WP_088028493.1\|3960988_3962092_-\|rod-shape-determining-protein-RodA	unknown	unknown	gnl\|CDD\|274033
NZ_CP015612.1\|WP_088027184.1\|3954947_3956021_+\|lipid-A-deacylase-LpxR-family-protein	unknown	unknown	gnl\|CDD\|378338
NZ_CP015612.1\|WP_088027173.1\|3945996_3946902_-\|decarboxylating-6-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236582
NZ_CP015612.1\|WP_088027168.1\|3942098_3943916_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226702

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_005411067.1\|3953165_3953444_-\|YbeD-family-protein	gnl\|CDD\|179161	PRK00907, PRK00907, hypothetical protein; Provisional.	1.56476e-63
NZ_CP015612.1\|WP_088027187.1\|3958702_3959848_-\|lytic-murein-transglycosylase-B	gnl\|CDD\|274066	TIGR02282, Membrane-bound_lytic_murein_transglycosylase_B, lytic murein transglycosylase B. This family consists of lytic murein transglycosylases (murein hydrolases) in the family of MltB, which is a membrane-bound lipoprotein in Escherichia coli. The N-terminal lipoprotein modification motif is conserved in about half the members of this family. The term Slt35 describes a naturally occurring soluble fragment of MltB. Members of this family never contain the putative peptidoglycan binding domain described by pfam01471, which is associated with several classes of bacterial cell wall lytic enzymes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	1.02544e-136
NZ_CP015612.1\|WP_088027171.1\|3944639_3945683_+\|oxidoreductase	gnl\|CDD\|183212	PRK11579, PRK11579, putative oxidoreductase; Provisional.	5.24889e-136
NZ_CP015612.1\|WP_005411057.1\|3941661_3942102_-\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.4568e-62
NZ_CP015612.1\|WP_088027182.1\|3952467_3953178_-\|lipoyl(octanoyl)-transferase-LipB	gnl\|CDD\|237681	PRK14342, PRK14342, lipoyl(octanoyl) transferase LipB.	6.24264e-139
NZ_CP015612.1\|WP_049447834.1\|3956110_3957331_-\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	9.56091e-148
NZ_CP015612.1\|WP_088027185.1\|3957431_3958706_-\|septal-ring-lytic-transglycosylase-RlpA-family-protein	gnl\|CDD\|223868	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane].	5.08108e-53
NZ_CP015612.1\|WP_088027164.1\|3939327_3940071_+\|20S-proteasome-subunit-A/B	gnl\|CDD\|239734	cd03765, proteasome_beta_bacterial, Bacterial proteasome, beta subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming an elongated alpha-beta-beta-alpha cylinder with a central cavity. The proteasome alpha and beta subunits are members of the N-terminal nucleophile (Ntn)-hydrolase superfamily. Their N-terminal threonine residues are exposed as a nucleophile in peptide bond hydrolysis. Mammals have 7 alpha and 7 beta proteasome subunits while archaea have one of each.	1.74767e-114
NZ_CP015612.1\|WP_088027166.1\|3940145_3941657_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|237526	PRK13837, PRK13837, two-component system VirA-like sensor kinase.	1.06813e-47
NZ_CP015612.1\|WP_088026673.1\|3962424_3963387_+\|transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	1.81246e-20
NZ_CP015612.1\|WP_088027175.1\|3948168_3948759_-\|DUF2242-domain-containing-protein	gnl\|CDD\|378349	pfam10001, DUF2242, Uncharacterized protein conserved in bacteria (DUF2242). This domain is found in various hypothetical bacterial proteins, and has no known function.	1.8528e-61
NZ_CP015612.1\|WP_049447832.1\|3953613_3954606_-\|peptidoglycan-binding-protein	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	5.09556e-10
NZ_CP015612.1\|WP_088027189.1\|3963466_3964579_-\|rod-shape-determining-protein-RodA	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	3.12183e-145
NZ_CP015612.1\|WP_088027169.1\|3944085_3944469_-\|BON-domain-containing-protein	gnl\|CDD\|225379	COG2823, OsmY, Predicted periplasmic or secreted lipoprotein [General function prediction only].	4.33443e-17
NZ_CP015612.1\|WP_088027177.1\|3949004_3951182_-\|tail-specific-protease	gnl\|CDD\|236873	PRK11186, PRK11186, carboxy terminal-processing peptidase.	0
NZ_CP015612.1\|WP_088028493.1\|3960988_3962092_-\|rod-shape-determining-protein-RodA	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	7.08448e-143
NZ_CP015612.1\|WP_088027184.1\|3954947_3956021_+\|lipid-A-deacylase-LpxR-family-protein	gnl\|CDD\|378338	pfam09982, DUF2219, Uncharacterized protein conserved in bacteria (DUF2219). This domain, found in various hypothetical bacterial proteins, has no known function.	1.61338e-111
NZ_CP015612.1\|WP_088027173.1\|3945996_3946902_-\|decarboxylating-6-phosphogluconate-dehydrogenase	gnl\|CDD\|236582	PRK09599, PRK09599, NADP-dependent phosphogluconate dehydrogenase.	0
NZ_CP015612.1\|WP_088027168.1\|3942098_3943916_-\|PAS-domain-containing-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	5.02621e-57

>NZ_CP015612.1|WP_088027177.1|3949004_3951182_-|tail-specific-protease
MKFKAPAFLMALALVAPLALAAKADSPALPAAATADQVTTSKLVYGLLSDSRYAYRPRALDEATSKDVFKRYLETLDGGKQYFTQADVARFAPFEANISSAIRGGELEPAFQVFAVYKQRVGERVAYARKLLKQEPDFTTDERFEYDRKKVPWAASSAELDELWRKSVKNDWLRLKLAGKKPDDIRKTLDKRYATLEKSVNELKGEDVFQFFMNSYTSAVDPHTDYFTPRTAENFNQAMSLSLEGIGAQLQRQDDVVVIREIIAGGPAAVDGTLKPGDRIVGVGQGKSGLVEDVIGWRIDDVVAKIRGAKDTQVKLEFIPAAEGADGKHHSLVLTRQKVRLAEQAAKGETMTIPAANGEPARKIGVIKLPTFYQDFEGRRRNAADYASATRDVAKLLAGFKNDKLDGVVLDLRNNGGGSLDEAIELTGLFIEQGPVVQVRESGGRVTVNSDRNQGVAWDGPLAVLINRGSASASEIFAGAIQDYGRGLVIGETSFGKGTVQNIVDLDRWPSGETQRFGQVKLTIAQFFRISGSSTQHKGVVPDLAFPASVDATEFGESTYDNALPWTRIAAVPHTQYGNFAPLLPKLETRHDTRIATDKEFQWWNEDVQQFRTEAAKKYISLNEATRRAERERQDTQRKERQVQRKELGLALDPLADDSSDDGLTGNERDIVKDAAREKAAEKRPDPLLRESASILADAVNLLANDRPLSAQVLPQSTGAGRWAD
>NZ_CP015612.1|WP_088027175.1|3948168_3948759_-|DUF2242-domain-containing-protein
MRASRLSSAVVALGSALILSACGGRAADSTLLRESFDSGDTYSRTVDGRPGDACEAARRTLLSQGYAIARSDEAQVEGSKNFQPREDDHEQLVLRISCAPRGSQTLVFVSAVQDRYALKKSPTSASVGVGALGSVSLPFGSNDDSLVKVASSTVTDAGFYQRFFQRLQQYLPAAAGTPAPPPAAPPEPAPASTDQG
>NZ_CP015612.1|WP_088028491.1|3946912_3948151_-|hypothetical-protein
MGVALLLAPALGSAAMAPDCRQGLLQRLGWRFDEAMVSAPLVHGGPVCTRASLAEAQAAGDLRVQWPAGMPLAARQAVLQELMDDSATVCAYAFRLGAATQRAASALQANPTFRFSGPQLGWIGFGLQGPLAQGWQRTRSFGRGFVPSAGNSQALQAFYSGAVRAECGVGRQVAQLATQRELYGDAAFDTEFAADELSIGTFLALHDTDSILLGAHAGDFFADGKAVRTSAMGRQAFVGVPGFIEHVYDKGMLDDLSNQAENFVVVDVGEGAAQALAMHGGLAWYDQRNVELWKLAQDIPRIGQRYFERLLFERDADLRARLEPRYHATLARMDQLLDDPFYQQFVIYVHPRGIRPIGYHVARLLDRNPRTPFSIDLAVHNLHTTLYRRWREAQLRHCAATGRPGSLTLDPN
>NZ_CP015612.1|WP_088027173.1|3945996_3946902_-|decarboxylating-6-phosphogluconate-dehydrogenase
MDIAMIGLGRMGANMAQRLHRGGHRVVGYDPGEGARQRAAEAGLEVVDSLAAAVAALPVPRVVWLMVPAGETVDQTLGQLTPHLAEGDIVIDGGNSNYQDTIRRAKALAEDDLGYVDCGTSGGVWGLQEGYSLMVGGEASVVEQIAPLLRTLAPAEDRGWARVGPSGAGHFTKMVHNGIEYGMMQAYAEGFALMERKQEMELDLAQVAEVWRHGSVVRSWLLDLSTEALKRNPSLDGIAPYVEDSGEGRWTVAEAIALDVPAPVITLSLLERLRSRESNSFTDRLLSAMRNEFGGHAIKKS
>NZ_CP015612.1|WP_088027171.1|3944639_3945683_+|oxidoreductase
MRPDLQLAMIGYGLAGRVFHAPLIQHTPGLVLHSIVSSQRDSLLRAFSDVHVRATPQEVFDDPAVDAVVIATPNEQHAPLAVAALAAGKHVLVDKPFALDVAEAETVLAAARDAGRIATVFQNRRFDADFLTLQALLAEGTLGDVAECHAHFDRYRPQVRERWREQDGPGSGLWYDLGPHLLDQMLVLFGWPEAIDADLAVQREGGSGIDYFHAVLHYPRHRAIIHSGSLVAAQTPRFSVHGSKASWIKHGLDVQEAQLRRGVAPGAPGWGIDPRHGELVRCDAEDNVQRTTVDNLPGDYRRLYARFAAAMHGDGEATVSAAQALQLMRLLQAGMDSAREGRRVQLG
>NZ_CP015612.1|WP_088027169.1|3944085_3944469_-|BON-domain-containing-protein
MSNTTRTLIASALTLGLALSSSAAFAKDPAAKSPPTSTHPATHADRHDSNEPVTDTWITTKVKADLLASSNVPGTEIKVETVNGVVSLSGAVATQAEKDKAVTAAKGIKGVTRVDAAALKVSAAAKR
>NZ_CP015612.1|WP_088027168.1|3942098_3943916_-|PAS-domain-containing-protein
MALVFSDDIWDRWRLPALALAAAAIIVVPWLTLRKLQQDNEEAMAWVNHTQAVGVALQQLQADVRDVESAALTLSKGVDAPGLRERMAKANDIPGRLAELGRMTRDNPDQLIRIGRIESMLEGRMALARELAKSEPNSDQRELVQDLSTRYPIRGLVEELQASEQKLLTLRAEQAARQRKQTELVSWTSLLVQLALLGLVLWLLQRQIGRRLHAERQSLRSAARAASVLQTVREPIVLLDRDLRVQLHNPAFAELYGLQDERADGLLLESVGDGAWQDAVVRQRLSDVLSRGRELWDFEHEQRTADGMARYMLLNARRMPLPDTDDEVVLLTVSDVTMQRAVQLRVEELNRQLEGKVAQVSEVNRELEAFSYSVSHDLRAPLRHVAGFSDKLSRHLGDAADDKSRHYLEVISSSARRMAALIDDLLVYSRLGRVAMRQQAVDMQSLVADTRAMLDSNLQAEAESTGHAHQVEWSIAPLPIVVGDENMIRQVWLNLLGNAVKYSGNREPAKIRVDYHPQPDGGHQFTVSDNGAGFDMAYAGKLFGVFQRLHKASDYPGTGIGLASVRRVLTRHGGRIWAEAEPDVGATFHFYLPPAIDADKQGPSA
>NZ_CP015612.1|WP_005411057.1|3941661_3942102_-|response-regulator
MTTLRTILLAEDSPADAEMAIDALEEARLANPIVHVEDGVEVMDYLLRRGAFANREEGLPAVLLLDIKMPRMDGLEVLRQIREHEELKRLPVVILSSSREESDLARSWDMGVNAYVVKPVDVDQFFGAVQTLGKFWALINQAPELE
>NZ_CP015612.1|WP_088027166.1|3940145_3941657_-|hybrid-sensor-histidine-kinase/response-regulator
MPLTGPALGALRILLVEDSPEDAELMSEQMLDAGLEARFERVESEAELRQALVAFQPDIVLSDLSMPGFSGDDALRIVRETSPEVPFIFVSGTMGEENAVAALQKGANDYIIKHLPARLPSAVARAIREARSAIERARVETELMRAQRLESLSLLAAGLSHDLRNILQPLLIMPDLLKARTEDPQLHHLADVIAECGRRGHEMAESMLSFVRGSRKPSERIEINGLFDAVALLLRSNVPDAVRLELQVQDEGLVVDANCTELQQVMLNLALNAIQAMPNGGRLSLTASHAGQRDGVDWMHIRVADEGIGMDADTLSHLFNPFFTTKADGTGLGLISCKRIVEGAGGSIHVSSQPGQGTCFELRLPMHDAIDGSEPIEQLVALGSGQSILVVDGEATRLSLLGNALSSQGYQLQLASDGPAALRWMQQEALPALVIADAGSKLLPASQLLGEMAALGYRGPALVLEDATVEVAADAFPAGVEVHVLRKPLQMQQVFRAVAEALG
>NZ_CP015612.1|WP_088027164.1|3939327_3940071_+|20S-proteasome-subunit-A/B
MTYCVGIEVDEGLVFAADTRTNASLDDVRVHRKLHVFEYPGQAAYVLMAAGNLATTQLLVSRLGRDASERRTPNLHDMTHLFEAAEYVGQLLVDSQVHSSHSEHGHDGVNTQATLIFGGQIAGERPGLYMIYPLGNAIAASPETPYLQIGESKYGKPILDRILSPATRLEDAARTAIVSLDSTIRSNLSVGLPIDLALLRDGELRIGQQLRLGADSALYADIHQNWSRRLEQAVDALPRFPWETLDR
>NZ_CP015612.1|WP_088027182.1|3952467_3953178_-|lipoyl(octanoyl)-transferase-LipB
MDAVADNCPAEAAPEDRAPRPALVRDLGRQAYEPVWRAMQRFTDQRSDADADELWVVEHDPVFTLGQAGKDEHVLAPGEIPVLHVDRGGQVTYHGPGQIVVYPLLRLPRLGIGVRDYVCRIEQAIIDTLAEWNIGAERREGAPGVYVGGAKIAALGIRVRRGCTFHGLAFNVAMDLEPFHRINPCGYQGLRVTSVVDLGGPSGMNAVKPVLLDHLARQFGLLLQHTPEPPDLSAAA
>NZ_CP015612.1|WP_005411067.1|3953165_3953444_-|YbeD-family-protein
MEIKSDNPDHGFQFPGQFELSAMGPANRGLEHELPRLLLAAGIDVVNERISWKHSSNGKYVSVRIVFKAESREQYDLAHQALRDHPEVKWTL
>NZ_CP015612.1|WP_049447832.1|3953613_3954606_-|peptidoglycan-binding-protein
MNKSNSLAHVLACALLGAGLVAVSAPASAGLRDSFANSRTSAQEQSKKGQAEIPVCTKPLGSISVIEPEDVVNWWTGQQLPAPSKLIKVFVNKSKCFTLVDRGVGMAAAQAERALASEGQLRGRSNIGKGQIRAADYVLVPDLISQNSNASGNAIGGLLGGLIGGKAGAVVGGLNFRSKTADVTLTLTDVRSSEQVAIVEGNSKKTDLGWGAGGGLFGGGGIGAMGVGGYANTEIGQVITLAYLQAYTNMVAELGGLPANASAANAGQAVTMLKAGRLLANAKGTGAPVRSLEPGMLLYPTGVKEGTMWEVEDEMGNKGWVNSTLMETAK
>NZ_CP015612.1|WP_088027184.1|3954947_3956021_+|lipid-A-deacylase-LpxR-family-protein
MSPPSQRRLTALGLSGLLAAALPLAAQAAEQCGPDAMRDHPPQINFRVDNDLFGGRHQDQGYTNGALLTLVSPNLVDYTDDPCLPRMARWVNQYLEGLHPGKFEQQNMIFSIGQGIFTPTDFSRRDLIEDDRPYAGVLIANFGFNARSGDRLQTTQLTLGVVGPWAQGKQMQNAVHEVLGDEKFKGWDNQLHNEPLFMLTHERMRRWPADASVNAGGWGWDAISHYGGAIGNLETKANAGGEVRFGWKLPDDFGSTPLRPAGENTAPTRGGRPNGWSWHMFVTTDAAWVIRDITLDGNTFRSSHSVDKRHVVAQGGYGMALMYGRWKFAVARYHSTREFYGQREAPVFGSFTISRSL
>NZ_CP015612.1|WP_049447834.1|3956110_3957331_-|D-alanyl-D-alanine-carboxypeptidase
MNFRSAATALAATLVVGLASAQTPLPTPATPAPAAAAAAPATVATPPAPAPSVSKAWVLMDYATGQVLAGENVHEQLAPASITKVMTSYVIAAEVKNGKVRADDQVMMSERAWREGGAGTDGSYSGFPVNQTARLEDMEKGMAIQSGNDAAIALAEHVAGSEEAFASLMNSYAAKIGMKDSHFVNAHGLTAQGHHSTAYDLALLGRAMVRDYPETYAYNKIKEFQVGNIKQPNRNLLLWRDGSVDGIKTGHTSEAGYCLMSSAQRGDQRLIAVVLGGASEKQRADDSLALLNWGFRFFETHRLYEPGKAVAEHKVWKGTTDKVQLGVAQPMLVSVPRGRYNDLKPSIDVPKTLEAPFTAGQQIGTVKVTLDGKVIAEAPLVAVAAVEQAGFFKRLWDSFWMWWESE
>NZ_CP015612.1|WP_088027185.1|3957431_3958706_-|septal-ring-lytic-transglycosylase-RlpA-family-protein
MNIRWLVPGLIVLALAACSSAPKKPATAGHGGKSSGTLVQGRGSRPAHCPEGSPYAAAKEDLSTRGNYTAGGLYKPGVRDSTPDYIPNVACIPEPEVTAEERSAIGNKTPYVVLGKSYKVLDDTRNYVERGTASYYGAKFHGRLTSNREVYDMYQFTAAHKTLPLPSFARVTNLDNGESVIVRVNDRGPFHDGRVVDLSYAAAVRLGITQRGTGNVEVRALQPGESNLMAQKPSRRERRAAEAAAASAVASARPAPTARAAADSDIDRLVKGLPADGMPARGQPATTQGVASTVPDVAVSSLPPSAPPARSTAYAPAPAVVASTTPRAVAPAPVRTTPASPSLSQQVVGAVMVQVASFSNRDNANRAMGQLNAAGIVGATISDIAAGGRTLFRLRVPASDHASAAELVGRIAGLGLGSPQIVKD
>NZ_CP015612.1|WP_088027187.1|3958702_3959848_-|lytic-murein-transglycosylase-B
MIRRTLACMLTLGLVACATQPKSPPSSPQASSTPRQPAAKAHGPAEAAPEAAAATAPPVDLTPVPFDVARARFIADTAKRYGLKPEQISSVLDQAQVRQPIIAAMSRPAERVKPWNEYRPMFISKARIDGGRAFLAQHRAELDRVQQRTGVPAEVIVAIIGVETSYGKNAGSHRVLDALYTLAFYYPRSGDPAKLEREVRRELFFRDELAKLFELGREENLDITTLKGSYAGAMGMGQFMPSSYLDYAVDGNGDGRRDLFTSYDDVFSSIANYFVKKGGWVRGGQVAVPATLAPGREEFNPTEWMPTWSMADLAQRGYQPSAPVQPGATATPITLEGSTGKQYWLGFQNYYAITRYNLSKMYAMAVFQLSQAIAGQELPPA
>NZ_CP015612.1|WP_088028493.1|3960988_3962092_-|rod-shape-determining-protein-RodA
MARVEWKRMLGGCREAVRTIDLPLLVALLILMAAGLAVLHSVSGPVAGQAARFAGGLAAMWLLSRVSLLRLRAWTPALYALSMLPLMAVYVIGTGKYGQRWLNLGVFYLQPSELLKLSLPLMMAWYLHRQPLPPSPRTVLTAAVLIGVPAVLILMQPNLGTATLVTASGVFALLLAGLHWGWVATGAAGLAVAAPLAWFGLLRQYQKDRVLTFLDPAADPLGTGWNILQSRIAIGSGGWQGRGWGQGTQATLDFLPEYTTDFAFSVLAEEFGWIGVATLFALYLFVVGRCLWIAVHARDTHARLLAGSLGLAFFVYVLVNGGMISGLLPVVGIPMPLISYGGTSAVSLLAGIGLVMAVRGHRPVHGG
>NZ_CP015612.1|WP_088026673.1|3962424_3963387_+|transposase
MSDRHAVGIDTDSRTLVVACHGTKGSIRIANSASAINKWLSSLPAKSRIGVEATNRYHELVVHAAQKADHAVFVLNPRDIKHYAKGVACRGKTDSGDAQVIARYIAKEADNLHEHVARSPEQERLHVLLQQRDSLVRSKAKLNLSLGAGASESALFGRIFSSLKEAIAMLDQQIQQLCRSGQQRDLYRRIMTIPGIGPTVAAFVTHHITRWPLANSDAWIACTGLDPRPNESGARIGRRRLSKRGNASLRQILYMAAMGLTRSKGGKPLYLAIRERGHSSTASFNILARKLAKIAWGVFKSGKDFDPAMLKVGQTCFQQA
>NZ_CP015612.1|WP_088027189.1|3963466_3964579_-|rod-shape-determining-protein-RodA
MKVFLRWAGDMLRRFFSTLDWVLCLALGALMVIGLATLKSAGGDGLVMAQGARFAVGMAALWGISRVPILRIRSATPMIYAISMIPLLAVFVLGTGKYGRQWLDLKFFYLQPAELLKVSLPMMVAWYLHKMPLPPRFNTVLVALVIIGVPTGLVMLQPDFGTGVLIAASGVFVLLLAGLPWWWVGLGVGGVTAVAPVAWFWLLRPYQKDRIMMFLDPEMDALGAGWNIIQSKIAIGSGGFDGKGWGEGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLALYLVVIGRCLWIASQSRDSYSRLLAGATGLAFFVYVLVNGGMISGLLPVVGVPMPLISYGGTSAVSLLAGFGLVMAVRSHNPVHGGYG

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Crispr_ID: NZ_CP015612_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_9

4204573-4204671

Orphan

Consensus_repeat	Method
CCCGACCAACGGTCGGGCGCTACCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_9

>merge|NZ_CP015612|9|4204573-4204671|CRISPRCasFinder
CCCGACCAACGGTCGGGCGCTACCGGTCCGGCGTGGTGGGTGCCGACCGTTGGTCGGTACACCCCTGATGTCGCCCGACCAACGGTCGGGCGCTACCGG

>NZ_CP015612|9|9|4204573-4204671|CRISPRCasFinder
CCCGACCAACGGTCGGGCGCTACCGG	TCCGGCGTGGTGGGTGCCGACCGTTGGTCGGTACACCCCTGATGTCG
CCCGACCAACGGTCGGGCGCTACCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088027542.1\|4202904_4203591_-\|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl\|CDD\|225438
NZ_CP015612.1\|WP_088027538.1\|4200393_4201107_-\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|235376
NZ_CP015612.1\|WP_088027552.1\|4209426_4211001_+\|sensor-domain-containing-diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP015612.1\|WP_088027540.1\|4201103_4201946_-\|response-regulator	unknown	unknown	gnl\|CDD\|381085
NZ_CP015612.1\|WP_088027560.1\|4215227_4216199_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027556.1\|4214277_4214694_-\|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl\|CDD\|214939
NZ_CP015612.1\|WP_049436839.1\|4201953_4202901_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|225088
NZ_CP015612.1\|WP_080011123.1\|4198678_4199068_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368831
NZ_CP015612.1\|WP_005419760.1\|4213864_4214224_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027546.1\|4204672_4206394_-\|ATP-dependent-RNA-helicase-RhlB	unknown	unknown	gnl\|CDD\|235307
NZ_CP015612.1\|WP_088027548.1\|4206904_4207234_+\|thioredoxin-TrxA	unknown	unknown	gnl\|CDD\|200072
NZ_CP015612.1\|WP_088027534.1\|4196955_4198239_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NZ_CP015612.1\|WP_088027544.1\|4203690_4204434_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP015612.1\|WP_088027532.1\|4195310_4196894_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP015612.1\|WP_088028507.1\|4211035_4211926_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|367555
NZ_CP015612.1\|WP_006473441.1\|4199239_4200115_-\|RNA-polymerase-sigma-factor-RpoH	unknown	unknown	gnl\|CDD\|235838
NZ_CP015612.1\|WP_088027558.1\|4214686_4215235_-\|GTPase	unknown	unknown	gnl\|CDD\|225138
NZ_CP015612.1\|WP_088027536.1\|4198362_4198695_-\|DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225495
NZ_CP015612.1\|WP_088027550.1\|4207463_4209215_+\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|236490
NZ_CP015612.1\|WP_088027554.1\|4211987_4213718_-\|bifunctional-isocitrate-dehydrogenase-kinase/phosphatase	unknown	unknown	gnl\|CDD\|368840

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088027542.1\|4202904_4203591_-\|cell-division-ATP-binding-protein-FtsE	gnl\|CDD\|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	2.84241e-112
NZ_CP015612.1\|WP_088027538.1\|4200393_4201107_-\|uracil-DNA-glycosylase	gnl\|CDD\|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	2.03112e-150
NZ_CP015612.1\|WP_088027552.1\|4209426_4211001_+\|sensor-domain-containing-diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.60812e-59
NZ_CP015612.1\|WP_088027540.1\|4201103_4201946_-\|response-regulator	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	1.73463e-16
NZ_CP015612.1\|WP_088027556.1\|4214277_4214694_-\|roadblock/LC7-domain-containing-protein	gnl\|CDD\|214939	smart00960, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	7.17026e-10
NZ_CP015612.1\|WP_049436839.1\|4201953_4202901_-\|ABC-transporter-permease	gnl\|CDD\|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	4.20687e-74
NZ_CP015612.1\|WP_080011123.1\|4198678_4199068_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368831	pfam06296, RelE, RelE toxin of RelE / RelB toxin-antitoxin system. RelE is a family of Gram-negative bacterial antitoxins of the RelE/RelB toxin-antitoxin system. Its cognate antitoxin is family RelB, pfam04221.	4.02681e-50
NZ_CP015612.1\|WP_088027546.1\|4204672_4206394_-\|ATP-dependent-RNA-helicase-RhlB	gnl\|CDD\|235307	PRK04537, PRK04537, ATP-dependent RNA helicase RhlB; Provisional.	0
NZ_CP015612.1\|WP_088027548.1\|4206904_4207234_+\|thioredoxin-TrxA	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	3.08493e-46
NZ_CP015612.1\|WP_088027534.1\|4196955_4198239_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP015612.1\|WP_088027544.1\|4203690_4204434_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.28148e-21
NZ_CP015612.1\|WP_088027532.1\|4195310_4196894_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP015612.1\|WP_088028507.1\|4211035_4211926_-\|TonB-dependent-receptor	gnl\|CDD\|367555	pfam03544, TonB_C, Gram-negative bacterial TonB protein C-terminal. The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.	6.88611e-08
NZ_CP015612.1\|WP_006473441.1\|4199239_4200115_-\|RNA-polymerase-sigma-factor-RpoH	gnl\|CDD\|235838	PRK06596, PRK06596, RNA polymerase factor sigma-32; Reviewed.	3.03668e-175
NZ_CP015612.1\|WP_088027558.1\|4214686_4215235_-\|GTPase	gnl\|CDD\|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	1.05293e-26
NZ_CP015612.1\|WP_088027536.1\|4198362_4198695_-\|DNA-binding-transcriptional-regulator	gnl\|CDD\|225495	COG2944, COG2944, Predicted transcriptional regulator [Transcription].	2.79215e-29
NZ_CP015612.1\|WP_088027550.1\|4207463_4209215_+\|transcription-termination-factor-Rho	gnl\|CDD\|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NZ_CP015612.1\|WP_088027554.1\|4211987_4213718_-\|bifunctional-isocitrate-dehydrogenase-kinase/phosphatase	gnl\|CDD\|368840	pfam06315, AceK, Isocitrate dehydrogenase kinase/phosphatase (AceK). This family consists of several bacterial isocitrate dehydrogenase kinase/phosphatase (AceK) proteins (EC:2.7.1.116).	0

>NZ_CP015612.1|WP_088027544.1|4203690_4204434_-|class-I-SAM-dependent-methyltransferase
MASVPCYDAFDLHYAQHVAASASRPLERRTLLELAGPLQGRDVIDLACGSGDFGRHLLLHGARSALGVDLSAAMIEQARQLSAQGGDAMQFLHGDATRLDMPARFDIAVAVWLFNHADTLQELERMYRATADVLKPGGRLLAIVTHPAFRLARGDFSRYGARIVGQQVLDDHHLVEVEFADAAVARVTDHQWRADQHEQAAARAGLPGLQWQAPVPTAAECQARPPGFWDEYRDNNALVVLHARKEA
>NZ_CP015612.1|WP_088027542.1|4202904_4203591_-|cell-division-ATP-binding-protein-FtsE
MSVLRFDNVSKQYAGGHEALTDVSFEVALGEMLFVTGHSGAGKSTLLKLIHLDERPSRGAVVFDERNLLKVRGGDVPRHRRAVGAVYQDHRLLMDRSIAENVALPLILRGTRRGDINKRVRSVLERMGLGHREKALPSQLSAGEQQRVGIARAIVGEPKLLVADEPTGNLDPTLAAEIMALFAELPARGTSVLVVSHDLPLLRRMRKRVLILDHGRLVDDISPQDLAE
>NZ_CP015612.1|WP_049436839.1|4201953_4202901_-|ABC-transporter-permease
MAKNENSEAAAPSRVGVWFQHHVHSVVFSLGRACRKPWATLLTVMVMALALALPLGLSIALDNLKQFAGSVQQSRDINVFLKGNVDGPGALRLAGQLRDRDDVAEVNVRTPEQGLQELRDAGLGEAIDALNDNPLPSLLVITPGQGKDDARLARALESLPEADLVQHDALWRQRLDAWLAFGARLVQVLSVLLGVGAALVVGNTVRLDIQARREEIGVLQLLGASDGFIRRPFLYLGAWYGLGAGAVALALIAAAGAALRVPLAELSRSYGSPFVLHGLDLLHGGLVLLGTLLLGWLGAWLVTGHFLRQTRPTDT
>NZ_CP015612.1|WP_088027540.1|4201103_4201946_-|response-regulator
MQPQALKHLEGPATRVMVVDGSKLVRKLIADVLQRDLPGVEVIGCDSIEEAQLALAQGPVDLVTTSLTLRDGDGLALARMVREAAGQAYVPVIVVSGDAQQHLEQRRFTEYVTDYFDKALGHEALATFIRGYVQPQTIPGATILYIEDSRVVAEATKRMLERQQLNVLHVVSAEEAFTLLTAESLGRSRHRIDLVLTDVTLKGELSGRDVVQRVRVDFGYGKRRLPVLVMTGDGNPHNQTGLLQSGANDLVLKPIEERLLVTKVLFQLRLARLNDGPLIR
>NZ_CP015612.1|WP_088027538.1|4200393_4201107_-|uracil-DNA-glycosylase
MMDEVADTPTIQLEPSWKQHVGDYLLQPQMRELSSFLRQRKASGAAVFPPGPQIFAAFDATPFEQVKVVILGQDPYHGRGQAHGLSFSVPPGVPVPPSLLNIYKEIESDLGIPRPDHGCLIPWAQRGVLLLNAVLTVEEGKAGAHQGRGWEGFTDHVVDVLNRERDGLVFMLWGAYAQKKGKVIDTRRHRVLKAPHPSPLSAHRGFLGCRHFSMANEYLQRRGQTPIDWSLPPRSAL
>NZ_CP015612.1|WP_006473441.1|4199239_4200115_-|RNA-polymerase-sigma-factor-RpoH
MSQNTSTALVANNLPIPSALGSLDAYIGAVHQIPVLSVDDEQDLARRFRDGNDLDAARELVHSHLRFVVHVARGYNGYGLALGDLIQEGNIGLMKAVKRFDPDMGVRLVSFAVHWIRAEMHEFILKNWRIVKVATTKAQRKLFFNLRKSKTRLGWMNAAEVSAVAKDLNVSEREVMEMESRLSGRDIGFDAPTDEDNEHAPPSPAAFLVANDEDPSMAYERADSEDNQMQLLREGLAELDARSRDIIRRRWLDADSKVTLQELADEYGVSAERIRQVEANALKKMKALFTA
>NZ_CP015612.1|WP_080011123.1|4198678_4199068_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MIMPRVFRTRSFNRSMRRTTLSDAALYRSVREMEAGLVDADLGGGILKKRVALPGRGKRGSVRTIVATQRGGHWFFLFGYEKNERAAITNAERDALQLYASEFLKMSTAQLNRAVQYGDLQEISHDEDP
>NZ_CP015612.1|WP_088027536.1|4198362_4198695_-|DNA-binding-transcriptional-regulator
MTKTPERRRAKSALLEAVHDAAVSLHAHGFIDKRRLSSYEALCLEPVPEYSSAQIRALRASLQLSQPVFAEVLNTSVSTVRSWEQGEKKPSGPSLKLLNLIDRKGLEAVL
>NZ_CP015612.1|WP_088027534.1|4196955_4198239_+|phosphoribosylamine--glycine-ligase
MKILVIGSGGREHALAWKLAQSSRVTEVIVAPGNAGTASEDKCRNVAVKVTDIDGLLALAQAEGLALTVVGPEVPLVAGVVDRFRAAGLRIFGPTAAAAQLEGSKAYAKDFLARHNIPTAFYAVHTEVDAALAYIREKGAPIVVKADGLAAGKGVIVAMTQAEAEDAVRDMLSGNAFGDAGARVVIEEFLDGEEASFISMVDGVHALPMATSQDHKRVGDGDTGPNTGGMGAYSPAPVVTPEVHARVMREVVNPTVQGMIADGIPFTGFLYAGLMIDASGAPKVIEFNVRFGDPETQPVMLRLQSDLVELVEAAIDGRLDQIEAQWDARPSLGVVLAARPYPESPITGDVISGLGDVPASAKVFHAGTTLDAQGQVLSAGGRVLCVAALGDSVRDAQANAYAGVAKVTWANEFHRNDIGWRAIAREG
>NZ_CP015612.1|WP_088027532.1|4195310_4196894_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MTADLLPVRRALLSVSDKTGLVELATALAARGVELLSTGGTAKAIRDAGLAVKDVADVTGFPEMMDGRVKTLHPMVHGGLLGRSGLDDAVMAEHGIGAIDLLVLNLYPFESVTAKADCTLADAVENIDIGGPAMLRSAAKNFARVAVATDPSQYAELLASLETNNGQLSAATRFAFSVAAFNRVAQYDAAISNYLSAVTATDAAVPARAEYPAQMNSTFVKVMDLRYGENPHQSGAFYRDLYPVPGTLATFQQLQGKELSYNNLADADAAWECVRQFDAPACVIVKHANPCGVAVGAGNGDAYELAYATDPTSAFGGIIAFNKPLDAATAKVILDRQFVEVLIAPDYEPAALEYAQKKANVRVLRIPHGDGLNNFDSKRVGSGLLLQSSDNRGMTRDELKVVSKLAPTDKQFTDLLFAWKVAKFVKSNAIVYAKDNRTIGVGAGQMSRVYSARIAGIKAADANLVVEGSVMASDAFFPFRDGIDAAAAAGIKAVIQPGGSMRDAEVIAAADEHGLAMVFTGVRHFRH
>NZ_CP015612.1|WP_088027546.1|4204672_4206394_-|ATP-dependent-RNA-helicase-RhlB
MSDKPLTDLTFSSFELHPALQAGLEGAGFTRCTPIQALTLPVALPGGDVAGQAQTGTGKTLAFLVAVVNRLLTRPALADRKPEDPRALILAPTRELAIQIHKDAVKFGSDLGLRFALVYGGVDYDKQRELLQQGVDVIIATPGRLIDYVKQHKVVSLHACEICVLDEADRMFDLGFIKDIRFLLRRMPERTTRQTLLFSATLSHRVLELAYEHMNEPQKLVVEAETITAARVRQRIYFPADDEKIPLLLGLLSRSEGARTMVFVNTKVFVERVARSLEKAGYRVGVLSGDVPQKKRESLLNRFQKGQLEILVATDVAARGLHIDGIKYVYNYDLPFDAEDYVHRIGRTARLGEEGDAISFACERYAMGLPDIEAYIEQKIPSEPVTKELLTPLPRPERPAPAAGEEGEDNESVGQIFREAREARAAEEERRGGGRSGGRSGGGGRGGRDGERSGERRPRGPRKPRVEGEQGAAAPVAGAEGAAAQAPRPPRPPRAEGAPEGAVDGEHKPRKRRRRRHGRPVEGAEGVQSAAGNGASPVTPVQVVAKPVRTAADTGDSFLTRIGRKIRRMLSGS
>NZ_CP015612.1|WP_088027548.1|4206904_4207234_+|thioredoxin-TrxA
MSDKVVHVGDADFDSAVLNSKEPVLVDFWAEWCGPCKMIAPALDELADAYQGRAKIAKVNVDHNRALAAKYHVRSIPYLVVFKDGEKVAEQIGAVGKAQLAGLLDKALA
>NZ_CP015612.1|WP_088027550.1|4207463_4209215_+|transcription-termination-factor-Rho
MSDNTSETGSADAPAEKRVRKPRVSKAAAPAAAETSAAPAQPTLPLAAVPEAPAPAAAAPAPSAPAAEAPASSGGGEGGEGRESGQPRQQNHQGGGQNQGQNPYNQNGQQGQGQGQGNRRDRFRNRRDRDRNNRFRDDGLPNDGGEQQPFVPRPHANVPEGFPVYSLSDLKRMPAQKLLEIAEQLQISEGVARARKQDVIFALLKVLTRHGDGVAADGVLEILPDGFGFLRAAEASYLAGPDDTYISPSQIRRFNLRTGDHISGRIRFPKDGERYFALNIVDTINGEPIEASKNKVLFENLTALFPRRRFTLERGNGSSEDITGRILDLMAPQGKGQRSLIVSQPKAGKTMMMQQVATAITTNHPDVHLIVLLIDERPEEVTEMQRTVRGEVISSTFDEPAARHVQVAEMVIERAKRLVEHKKDVVILLDSITRLARAYNNVVPSSGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALVDTGSKMDEVIYEEFKGTGNSEVHLSRRIAEKRVFPAIDINRSGTRREDLLIEPELLQKIWILRKLLHPMDEMAAMEFLLDKMKNTKSNDEFFGSMKR
>NZ_CP015612.1|WP_088027552.1|4209426_4211001_+|sensor-domain-containing-diguanylate-cyclase
MRTLSPRLNLGKLILALALLSAIIALANTLLASYRVQRDQLVGNTLEANRVYATKLAETTQNFLLAAQQQLAYAATRLGEDDLDPKQAQDEASRLQLQSSSFNSSLVVDADGLVIATSPQTLQLQGEVLHSVGNNAALAARQPMISDPYQSATGKLLVSLSHPIFDRQGRYRGYVSGTLYLRQRSALHTLLGKHYYRDGSYLYVVDRNGRLLYHADGKRVGDYVVGNPAVKAVVRGERGAQQVRNNRGVSMLAGYAPVAATGWGIIAQRPTEATLQPLSRLMTAVIWNAIPLGLLSLLVTWWFARRISMPLWQLARNVQGGEDTGNAINHVSGIRAWYFEVAQLKQAVLHSFNALQDRIGTLNRASRTDPLTGLLNRRGLQQALDALQVQGIPFAILALDIDRFKSINDSYGHDVGDNAIVHIANQMRRYSRDSDILCRAGGEEFLLLLPGISTESARQAGERLRQHIADHPFEPVGTITVSLGVAHFPSFHVDAEQALRLADKALYMAKEQGRNRVVIYPYAD
>NZ_CP015612.1|WP_088028507.1|4211035_4211926_-|TonB-dependent-receptor
MMRSPLFLALALAVGAGTPLLAGQASAQTARAVRATAEMSMVLSGHIEITPEGEVSSLVLDQKSALTPSIASFVEGTIGGWRFEPTLHDGKAVAARAPMRVRLRGTQMADGGYQVSMTSVDFSEYDPKATDSVTKMRITPPRYPDEAYRNGAQGEVLLMIKVARDGTVADVIAEQVNMTVVGPERAMAKMRDILARASISSARSWTFNPPTTGEDSTRDSWEVRVPVGFALGNDRNTAQERYGRWRAFIPGPRQTIPWRKSAPVERGGSDLLPEGGVYMVDGAKRGVRLLTPLEES
>NZ_CP015612.1|WP_088027554.1|4211987_4213718_-|bifunctional-isocitrate-dehydrogenase-kinase/phosphatase
MSQPDIAAELAPRIASAIRDGFEQYHARFAAITARARQRFEQCDWAGARQDAVERIALYDLCIAEQMDTLRRLAGDAIGERALWLQVHARYSALLQGLIDAELYKTFYNTLSRRLFATRGVDPALEFVAFDVEPSDAITHPVARHTYAVSPTRPVEALQRVLADYRFDIPYAHQLRCAAAIAVRLQDDLAHWGDTPVRSIELLDTVFYRERRAYLVGRVFGEHRFSPCVIALVNDRHGLRADAVLTRRRDVAHLFGVSRSYFQADLRTVGDAVVFLRSLLPGKPIDEIYTVLGRAKQGKTERYRTFFRHFNEHPQERLVHAEGTPGMVMAVFTLPSYPLVFKLIRDRFAWPKAMSRQQVEEKYALVFNLDRVGRLLDAQPYRHLRFPRDRFAPALLAELLEQCAQSVRVDGDQVEVSLCYVQRRFRPLNLYLREQGGEAVRAAVLDYAQAITDMARNNIFPGDMLPKNFGVSRHGRAVFYDYDELCLVSDCVFRAWPQPRTPEEAMADEPWFHVGPRDVFPERFGPFMGLPASELAAVREHYRHLFDPGWWQGLQERFARGDYPDTPPYAGTHRLA
>NZ_CP015612.1|WP_005419760.1|4213864_4214224_-|hypothetical-protein
MAGLNESLNALMGIDGAQAVALVDYESGMLLGEAGAGMDMEVAAAGNTEVIRAKMKTAASLNLNDSIEDILISLGKAYHIMRPVAKKKGLFFYIVLDRTKSNLALARRKVQDVEAELAI
>NZ_CP015612.1|WP_088027556.1|4214277_4214694_-|roadblock/LC7-domain-containing-protein
MADGQMAVLPDAGQRERLQPLLQDLQQRVEGVRTVVLASVDGFALVSAGAEGRGERLAAMTSAMLALAAAVGRELVLGDLQTLMLEAVGGKVLMLAIQADGRAPLLLMAACDQRSVIGQVLWQSRECGQAILAELGGS
>NZ_CP015612.1|WP_088027558.1|4214686_4215235_-|GTPase
MREHKVVVLGGMGSGKSTLVRSIAAGAVIDTDVTNSDRLGADKASTTVALDYADIDLPNGERLRLYGTPGQQRFDFLWPILLQGARGAVLLLDARRAGLASELEDYLQVLQPFASSLALVVAVTHLDQATQAALEDWSARACLDDQPLPLLAVDARDREQGLLLMDVLMSEMEAHALVAAHG
>NZ_CP015612.1|WP_088027560.1|4215227_4216199_-|hypothetical-protein
MARVLVVGTDIQGEQALLQRLRVASALPDGQIRRSQDLDDCDLLVIRDTPALRNAAQRMRQQRPRLQCWIEDLGGQLRDGDGHQDVLDDGAIGRALRGMQLAVEPLAMPAPAPIRLADGAHAITRLLRERLPLRQGQALLSDAGEPLLLMDLEHDQAVLLQEPVAALVERLADAFERLQLDALTPARLQALAGERPRQPLRPLLWQWAQRSRHWQALDERLRGASVKLLRWPDFRVLGHDHDGFRLCSLLLKRACTVDECAMLLELPAAAVRDFIHAAYLCGYAQLQSAPVAPMTAVRGSGPGTDNGLLARLWRHLRGSERNA

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Crispr_ID: NZ_CP015612_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_10

4278293-4278402

Orphan

Consensus_repeat	Method
CCGGTAGATCCACGCCATGCGTGGATGCGGTCAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_10

>merge|NZ_CP015612|10|4278293-4278402|CRISPRCasFinder
CCGGTAGATCCACGCCATGCGTGGATGCGGTCAGGCTCCGTGCCGACCAAGGTCGGCACCCACCAAGAGCGGCAACCGGTAGATCCACGCCATGCGTGGATGCGATCAGG

>NZ_CP015612|10|10|4278293-4278402|CRISPRCasFinder
CCGGTAGATCCACGCCATGCGTGGATGCGGTCAGG	CTCCGTGCCGACCAAGGTCGGCACCCACCAAGAGCGGCAA
CCGGTAGATCCACGCCATGCGTGGATGCGATCAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_088027637.1\|4277680_4278226_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027649.1\|4283075_4283681_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|379399
NZ_CP015612.1\|WP_088027623.1\|4268837_4269323_+\|DUF962-domain-containing-protein	unknown	unknown	gnl\|CDD\|226914
NZ_CP015612.1\|WP_088027655.1\|4286592_4287675_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|213783
NZ_CP015612.1\|WP_005411334.1\|4274908_4275193_+\|K+/H+-antiporter-subunit-F	unknown	unknown	gnl\|CDD\|180435
NZ_CP015612.1\|WP_088027653.1\|4285381_4286257_-\|tryptophan-2,3-dioxygenase	unknown	unknown	gnl\|CDD\|188272
NZ_CP015612.1\|WP_088027629.1\|4272873_4274409_+\|monovalent-cation/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|237166
NZ_CP015612.1\|WP_087924242.1\|4287748_4288735_+\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP015612.1\|WP_012481450.1\|4275189_4275579_+\|Na+/H+-antiporter-subunit-G	unknown	unknown	gnl\|CDD\|237169
NZ_CP015612.1\|WP_088028511.1\|4279827_4280898_-\|4-hydroxyphenylpyruvate-dioxygenase	unknown	unknown	gnl\|CDD\|225726
NZ_CP015612.1\|WP_005411349.1\|4288736_4289090_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|212789
NZ_CP015612.1\|WP_088027651.1\|4283700_4285200_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP015612.1\|WP_088027633.1\|4275862_4276828_-\|sodium:calcium-antiporter	unknown	unknown	gnl\|CDD\|223604
NZ_CP015612.1\|WP_088027644.1\|4281644_4282784_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|129795
NZ_CP015612.1\|WP_088027625.1\|4269656_4272485_+\|monovalent-cation/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237157
NZ_CP015612.1\|WP_088027627.1\|4272484_4272877_+\|Na+/H+-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|236377
NZ_CP015612.1\|WP_088027635.1\|4276901_4277555_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027631.1\|4274405_4274912_+\|Na+/H+-antiporter-subunit-E	unknown	unknown	gnl\|CDD\|181598
NZ_CP015612.1\|WP_088027642.1\|4281006_4281564_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP015612.1\|WP_088027640.1\|4278434_4279742_-\|homogentisate-1,2-dioxygenase	unknown	unknown	gnl\|CDD\|235421

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_088027649.1\|4283075_4283681_-\|thioredoxin-family-protein	gnl\|CDD\|379399	pfam13899, Thioredoxin_7, Thioredoxin-like. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond.	0.000408666
NZ_CP015612.1\|WP_088027623.1\|4268837_4269323_+\|DUF962-domain-containing-protein	gnl\|CDD\|226914	COG4539, COG4539, Predicted membrane protein [Function unknown].	3.33593e-15
NZ_CP015612.1\|WP_088027655.1\|4286592_4287675_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl\|CDD\|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	1.00708e-174
NZ_CP015612.1\|WP_005411334.1\|4274908_4275193_+\|K+/H+-antiporter-subunit-F	gnl\|CDD\|180435	PRK06161, PRK06161, putative monovalent cation/H+ antiporter subunit F; Reviewed.	1.64199e-36
NZ_CP015612.1\|WP_088027653.1\|4285381_4286257_-\|tryptophan-2,3-dioxygenase	gnl\|CDD\|188272	TIGR03036, trp_2_3_diox, tryptophan 2,3-dioxygenase. Members of this family are tryptophan 2,3-dioxygenase, as confirmed by several experimental characterizations, and by conserved operon structure for many of the other members. This enzyme represents the first of a two-step degradation to L-kynurenine, and a three-step pathway (via kynurenine) to anthranilate plus alanine. [Energy metabolism, Amino acids and amines].	6.31766e-131
NZ_CP015612.1\|WP_088027629.1\|4272873_4274409_+\|monovalent-cation/H+-antiporter-subunit-D	gnl\|CDD\|237166	PRK12666, PRK12666, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_CP015612.1\|WP_012481450.1\|4275189_4275579_+\|Na+/H+-antiporter-subunit-G	gnl\|CDD\|237169	PRK12674, PRK12674, putative monovalent cation/H+ antiporter subunit G; Reviewed.	7.3016e-33
NZ_CP015612.1\|WP_088028511.1\|4279827_4280898_-\|4-hydroxyphenylpyruvate-dioxygenase	gnl\|CDD\|225726	COG3185, COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only].	1.12825e-153
NZ_CP015612.1\|WP_005411349.1\|4288736_4289090_+\|hypothetical-protein	gnl\|CDD\|212789	cd11855, SH3_Sho1p, Src homology 3 domain of High osmolarity signaling protein Sho1p. Sho1p (or Sho1), also called SSU81 (Suppressor of SUA8-1 mutation), is a yeast membrane protein that regulates adaptation to high salt conditions by activating the HOG (high-osmolarity glycerol) pathway. High salt concentrations lead to the localization to the membrane of the MAPKK Pbs2, which is then activated by the MAPKK Ste11 and in turn, activates the MAPK Hog1. Pbs2 is localized to the membrane though the interaction of its PxxP motif with the SH3 domain of Sho1p. SH3 domains are protein interaction domains that bind to proline-rich ligands with moderate affinity and selectivity. They play versatile and diverse roles in the cell including the regulation of enzymes, changing the subcellular localization of signaling pathway components, and mediating the formation of multiprotein complex assemblies.	7.24408e-09
NZ_CP015612.1\|WP_088027651.1\|4283700_4285200_-\|MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	9.75675e-142
NZ_CP015612.1\|WP_088027633.1\|4275862_4276828_-\|sodium:calcium-antiporter	gnl\|CDD\|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	4.63999e-43
NZ_CP015612.1\|WP_088027644.1\|4281644_4282784_-\|hypothetical-protein	gnl\|CDD\|129795	TIGR00712, Glycerol-3-phosphate_transporter, glycerol-3-phosphate transporter. This model describes a very hydrophobic protein, predicted to span the membrane at least 8 times. The two members confirmed experimentally as glycerol-3-phosphate transporters, from E. coli and B. subtilis, share more than 50 % amino acid identity. Proteins of the hexose phosphate and phosphoglycerate transport systems are also quite similar. [Transport and binding proteins, Other].	0.00975748
NZ_CP015612.1\|WP_088027625.1\|4269656_4272485_+\|monovalent-cation/H+-antiporter-subunit-A	gnl\|CDD\|237157	PRK12648, PRK12648, putative monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_CP015612.1\|WP_088027627.1\|4272484_4272877_+\|Na+/H+-antiporter-subunit-C	gnl\|CDD\|236377	PRK09094, PRK09094, putative monovalent cation/H+ antiporter subunit C; Reviewed.	2.85462e-62
NZ_CP015612.1\|WP_087924242.1\|4287748_4288735_+\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	9.03877e-165
NZ_CP015612.1\|WP_088027631.1\|4274405_4274912_+\|Na+/H+-antiporter-subunit-E	gnl\|CDD\|181598	PRK08965, PRK08965, putative monovalent cation/H+ antiporter subunit E; Reviewed.	1.02275e-61
NZ_CP015612.1\|WP_088027642.1\|4281006_4281564_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	9.86745e-16
NZ_CP015612.1\|WP_088027640.1\|4278434_4279742_-\|homogentisate-1,2-dioxygenase	gnl\|CDD\|235421	PRK05341, PRK05341, homogentisate 1,2-dioxygenase; Provisional.	0

>NZ_CP015612.1|WP_088027637.1|4277680_4278226_+|hypothetical-protein
MQPRKTDLARTALQAHRAPLDMRQRRLLILCDGQRSIAELTGLLGPEAPAMVIQLVQAGYLSTGLATATPTPSSSAVIVPEPVAAAPARAAAPAIQVERRRSLVAARIYVLGILEMQRHPQAAALFRDLQQARAEDEVLQRLQSAMQMLPGLTSDGYCQRVRQRLLEALPLEHCDAFAEVA
>NZ_CP015612.1|WP_088027635.1|4276901_4277555_-|hypothetical-protein
MKHLPIAGLLLLSLTACGGHDKQGAAGSGSDTPAETASATGPALSTDPDLAARPANDRREDSPARLDGFAGATLGAGIAEVRSGFGTPLQGLGTDASGKPLPADDSNDGCYFLRPQDAEDPRLMIEGRKLVRYDVRSAAITAPGGGKVGMTLGELQVLYPERGDVGPDKYDEKAQHLRVRPAQEGGAVIDFALGADGRVGAWRVGQTPQVDYVEGCG
>NZ_CP015612.1|WP_088027633.1|4275862_4276828_-|sodium:calcium-antiporter
MIAIAIAWFLLGLLLLALGGDSIVKAVSGLAQRFGASPFTAGLLLLGVTTSLPELAVNARALAVGQPELALGNAVGSSIVNLGLTLAVAAIAAPLLLRARLQTVLWWSLLAAGVLLILFGLDGGLARWEGGVLLAGFIVVQVLLLRRGRSESAEVQAAIAESALSRTSLPLNVLRVLIAALALYWGARLVVGAAADFGAALGWTPLLVGLLPVAIGTALPEVTTAIAAARRGHGDMVLGHVLGSSVVNLLLVIGAMAVLQPLALPASFVRLELPALLAFALVLYPMLRGDLKISRGEGVILLVAFVGWFVLELLLVGAPAL
>NZ_CP015612.1|WP_012481450.1|4275189_4275579_+|Na+/H+-antiporter-subunit-G
MITAIQIGLSILLLFGCFFILVGALGLVKLSTFFKRLHAPTKASTLGVGCVLVCSVCYHIFLGQDPQPRELLITVFLFITAPISAHMMAKAALSLLMETRPTLPGNERAAEEQLPPPEPVREEETTQNR
>NZ_CP015612.1|WP_005411334.1|4274908_4275193_+|K+/H+-antiporter-subunit-F
MTGFEVIQTTLVVCMHVVGLAMLLATWRLLRGPTVPDRILALDTLSVTAIAELMLFGMYLNSPIYFEAALIIAMLGFGSTVVLSKFVLRRDIVE
>NZ_CP015612.1|WP_088027631.1|4274405_4274912_+|Na+/H+-antiporter-subunit-E
MTAQRSLFRRAIPSPMLSIMVVAFWLLMSDSFTLGQIVLGLVLGVVVPLFAARLDREFARIGTLRPLPKLLCVTLWDILMSNIRVAIQVLGPEKNIHPGFIWLPLDIANIHGIAALTSMITLTPGTVSAALSDDRKFLLVHVLHLEDPQDLIDTIKRRYEAPLMEIFP
>NZ_CP015612.1|WP_088027629.1|4272873_4274409_+|monovalent-cation/H+-antiporter-subunit-D
MNHLVILPILIPLLGAALSLFVEHRRYGPKVQRAVAWTALSALALAVGLLFSTTAGGEINVYLLGDWPSRLGIALVADRLSAWMLLTTLLLAIPCLLHACSGWDRRAPHFHALFQFQLVGLNGAFLTGDIFNLFVFFEVMLIASYGLLLSGGRGLRMRIGLHYVVFNVTASTLFLIALGLLYASLGSLNMAELSQRIAEVPPAQLTLVKATMGLLLLVFCAKAALMPLYLWLPEAYSRAPAAVAALFAIMTKVGLYSVLRIQMLWFGDDAGAMAGYGRDWLLWAGVATLVLGGLGALAATRLRVLISYLVIVSAATLFIAFSVGTPKVLSAGLYYLPHSSFVAAALFLVADLIRRRRGGASDRKEVVAPMPGKETPAVLFLIGAVSVAGLPPLSGFLAKAALLAGMPAQYTGPVWTAVLVSSLLVIMGLTRGGIRLFWRVPPVEADAPKPRKARLRRVELYAACILLAYGIGMTLAAAPLMRYTDATAAQLLQPSEYVQQLRATTPEIRQP
>NZ_CP015612.1|WP_088027627.1|4272484_4272877_+|Na+/H+-antiporter-subunit-C
MELALATAIGVLTAIGIYLLLRARSFDVILGMTFLSYATNLLIFAGGRVVLGKAPVLQEGLDSHLGNYTDPLPQALVLTAIVIAFAMTAVSIVLAMRSRSDNHSDHVDAHEPDDDLQDERVPPRQGEDRV
>NZ_CP015612.1|WP_088027625.1|4269656_4272485_+|monovalent-cation/H+-antiporter-subunit-A
MLPSLPLLLALPFLMAAAVAAFPRSSRSTAAWLAALAPLGGLAILGWLTPSVLDGQVVRTMVPWLPQIGLDFTLRLDGLAWMFAGLVLGIGALVVLYARYYLSQHDNAHRFYCYLLLFMGAMLGMVLSGNLLLLMIFWEMTSISSFLLIGFWSHRQDAREGARMALVITGGGGLALLGGVLLIGRIVGSFDLDVVLAAGEQIRASALYPYALFLVLAGIFTKSAQFPFHFWLPHAMAAPTPVSAYLHSATMVKAGVFLLARLHPALAGSDLFFYTVSGIGALTLLIGAWNAIFQHDLKGLLAYSTISHLGLITLLFGLSTPMAVVAGVFHILNHATFKASLFMAAGIIDHETGTRDMRKLGGLRRLMPFTSALAIIASLAMAGIPLLNGFLSKEMLFAEAITAGGPGIMRTAVSVAALLAGVFGVAYSLRFVHDTFFGPGPHDLDRVPHEPPRWMKVPVELLVVICIAVGVAPALTVAPVLHAAAASILGPAMPEYSLAVWHGFNLPLAMSAIGVVGGVALYFGLRKLINLHDVTNVSTGRNVFHAQLDAVSALAMRLTNGIANGSLQRMLLGLVLVAIAVAAAPFVANPASPNWTAPQPIPLLGWALWLVMMACAVATLRVYKQRLLAVLLVGGVGLMVALTFVFLSAPDLALTQLLVEMVTLVLMLLGMNYLPAQSGPERPRWRKRRDAVIAIIAGAGLGALAYSAMTLPPNTMAGELLARALPEAYGQNVVNVILVDFRGFDTFGEITVFGIAALVVHALLRRTRMAPEQIMPGPPIKLPVPADLAQIMFPLTLTVSIFLFLRGHNAPGGGFIAGLVLAVPLLIQYVIQGTASVESRFGFDYIRCIGMGLLIALLSGSASMLFGVPFLTSGHLDLHVPLIGDVPLASAIGFDIGVYLVVFGGAMLMLSMMGTIKPSRTRTARKGEIDLQRRSARTGEMH
>NZ_CP015612.1|WP_088027623.1|4268837_4269323_+|DUF962-domain-containing-protein
MQTSTELARPIDRYFASYSDDHRNVINQRIHVVAVPAILWSVVALLWCLPPLITWFQYGIWSAFAMFSAWCFYNKLSRPLGIGMLIQFFVFGCLCRLLEAEIGLHNLLWLAVGVFVVAWIAQFIGHKFEGRKPSFLTDLTYLLIGPAWVMAKFYRKLDWRY
>NZ_CP015612.1|WP_088027640.1|4278434_4279742_-|homogentisate-1,2-dioxygenase
MSTAITARGYQSGFGNEFATEAVAGALPVGQNSPQKVAHGLYAEQLTGTAFTAPRGSNRRSWLYRIRPAVTHGEFTPFAQSQLQCDFGAQPASPNQLRWSPLPLPELPTDFVEGLYTMGGNGSPDAHAGVGIHLYAANRDMVGRYFYDADGELLIVPQLGALRLLTELGVIEIEPQQIAVIPRGVRFRVELPDGPSRGYICENYGALLKLPDLGPIGSNGLANPRDFETPHAAFEDVDGDFELIAKFEGRLWRAPIDHSPLDVVAWHGNYAPYRYDLRRFNTIGSISYDHPDPSIFLVLHSPSDTPGTSNMDFAIFPPRWLVAQNTFRPPWFHRNIASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDAPTFDKASNADLSKADVIKDTMAFMFETRAVIRPTAQALAAAHRQGDYQQCWNGLRNNFRSSR
>NZ_CP015612.1|WP_088028511.1|4279827_4280898_-|4-hydroxyphenylpyruvate-dioxygenase
MQVTTFENPMGIDGFEFVEFAAPAGRGQELHEYFRKMGFSAVLKHKQRPITVYRQGDVNFLVNEDPDSFASDFAEKHGPCACGFAIRFKKPGAEVYQTALGNGAEAIVFKPDSKAVSAPVIKGIGDCMLYLVDRYGSAGSIYDGDYEPIAGADLHPVGFGLTFIDHLTHNLYFGNMQQWSDYYERLFNFREIRYFDIKGLKTGLVSKAMTAPDGIVRIPLNESSDPKSQINEYLDAYKGEGIQHIACFTENIYETVEAMRAQGVDFLDTPETYFDVIDQRVPNHGEDVARLAKNKILIDADPETHQRKLLQIFTQNCIGPIFFEIIQRKGNEGFGEGNFTALFESIERDQIRRGVL
>NZ_CP015612.1|WP_088027642.1|4281006_4281564_+|winged-helix-turn-helix-transcriptional-regulator
MQGLDLPLIVTLETTSKVHRNMSPADPVSTRLRSSHVLLDLEQFLPYRLSVLSNRVSGNIAKLYGDRYGLAIPEWRVITILALYPGSSASEVSDRTAMDKVAVSRAVARLLERGFIKRETHGDDRRRSVLALSAAGFEVYETIAPMVIEITRKLMSVLSDEEEQVLEKLILRLAGEGLERMGEGV
>NZ_CP015612.1|WP_088027644.1|4281644_4282784_-|hypothetical-protein
MHSDHAERLPEPASDLAEAGAGEGVTLPPQEALLDDASTGEDSVELAPPRHRLPQIALPDNVVLKGAVQKLVEQKSRLDALAADGQLAGLLPPEWQGHGVRAIELSTFIQGVLPFLQPGERGETAPARLPVRHVLGDDSRWGLDDVAEPKSLAWYLASDERATAGSKDVAEAYLVGALGLAWMQEGRSRPGFLRAMGQDSLAARVTMLGYPPANELALYSVTAHGQPQIWCVHGRRRMRPLVAPWLSVPVLTAYGVPAPVAWPSSFPPVEAVAELLATARQGRAVPEVDLGKAVAKIAEDAVSEAWQPVSLLQLNTWSPRWHFFLGTFVGLPSLLLVAAALALPGAVEAATVAASLGFAGGAIAALAVPWIHARRKHLS
>NZ_CP015612.1|WP_088027649.1|4283075_4283681_-|thioredoxin-family-protein
MRSKLGTAAVVVCAALIGACSQPQPPATAEPTQPLDTRPTEPPVADPSEPVASGNTPVAADIAAIAGLGAQFDPARDPADDLATAKVEAQRGKKRILLEVGNAACDRCQTLDELVEGNGDLRRFRDAHYVWVKVNASDEQPNAAFFAQFPMMQRDYPYLLVLDADGGLLVSQATGELRRGQAFQPARVSAFLKQWAPDKPE
>NZ_CP015612.1|WP_088027651.1|4283700_4285200_-|MFS-transporter
MSVNATANTPEPALPDFKTTLGHPRPLWMLFMTEFWERFAFYGIRWALVLYIVAQFYNGNAAGEGDASRIYGAYLALVYAAAIFGGYVADRVLGYQRSILTGAIIMAAGLFMISLPQEHIFKLGLATIIVGNGLFKPNISTMVGKLYGLKDERRDSGFTIFYMGINIGAMIAPVLTEYMARKVFGTTEMPSYKVVFIASGVGMLISLVWFYIGRAGLKGIGAPPAGAEGFGRIIMVLVGAVVAIPVAYFLLATGATALAWILGAMFTALAILLLVEGIREGKVQRDRVIAMLIIFAFNVMFWMFFEQAGSSFTFLAENIVNRQFGDWTFPTAWFQSVNSVAIITLAPVIAWIWVAMGRANPSIPRKFGLGLLFNGAAFALLMFALSQMVVDGKIPFWTLFMVYVIQSVGELCLSPIGLSMVTKLAPVRLVGFGMGGWFLSTGIGNNLSGIFAGVVSGEGGMTVESALKGYTFGFWALIGSGVVLFLIAPLINKLMHGVK
>NZ_CP015612.1|WP_088027653.1|4285381_4286257_-|tryptophan-2,3-dioxygenase
MSVDNNQRDLEAGIHTDLQGRLTYGGYLRLDQLLSAQQPLSKPPHHDEMLFIIQHQTSELWLKLLGHELRAAIGFLQRDEVWQCRKVLARSKQVLRQLTEQWSVLETLTPSEYMGFRDVLGPSSGFQSLQYRYIEFLLGNKNAQMLQVFEHDAAGQAQLRTVLEAPSLYEEFLKYLARFGHAVPAVYESHDWTQPHVADDALQPVFERIYQDTDRYWREYSLCEDLVDLETAFQLWRFRHMRTVMRVIGFKRGTGGSSGVGFLAKALELTFFPELFQVRTSLQAAPPAELG
>NZ_CP015612.1|WP_088027655.1|4286592_4287675_+|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MTVAAEFKIEYLQYLDVDGKLVRDDLPASLRDPKVLVPLFKQMLFVRTFDSKSIALQRTGKLGTYAACLGHEAAHVGIGAAMQKDDVFAPSYREYGAMFMRGVRPHDVLMYWGGDERGNDYGGNAAKDFPFCVPISTQCLHAAGAALKFKLNKEPQIAVAVCGDGGSSKTDFYAALNSAGAYKLPLILCIVNNGWAISVPRSAQTGAETLAQKGLAGGLHCLQVDGNDLIAVLAAMEQARERALAGDGGTVLELMTYRLSDHTTADDARRYRDDAEVKDAWQREPMLRLRKYLINAGVWSEEEETAWVAECGTRVDEEVNLYLNTPVQPVEAMFDFLYADPPPDLLAQRAQAIALEKRHG
>NZ_CP015612.1|WP_087924242.1|4287748_4288735_+|alpha-ketoacid-dehydrogenase-subunit-beta
MTTTPITLIEAITQALAWELEHDPSVLVLGEDVGVNGGVFRATAGLQQRFGSERILDTPLDETTIAGLTIGLAAQGMKPVAEAQFDGFMYPMVDHIVCHAARLRYRTRGRLHCPMVLRVPWGGGIRAPEHHSEANEAIFTNVPGLRVVLPSSPQRAYGLLLAAIREPDPVIYMEPKRIYRQYKEVVVNDGEALPLDVCFVLRDGTDVTLVTWGAQVKEALEAADKLAGEGISAEVIDVATLRPLDFATIAESVAKTGRCVIVQEAPKTAGFGAEIAARLAEESIYDLLAPVERVTGYDTHIPLFRLEMKYLPSVERIVAAAKRAVAAG
>NZ_CP015612.1|WP_005411349.1|4288736_4289090_+|hypothetical-protein
MRARLLGAYRSQYPNPLRFHTGQIVEVGVRDEEWPAFAWVRTNDGRAGWAPIAWLQLLDEGRAEALCDYDARELDVESGEMVKLHHEHGGWWWSERANGATGWLPARELELLEENCK

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Crispr_ID: NZ_CP015612_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_11

4317627-4317768

Orphan

Consensus_repeat	Method
CATCAAAAGCGCCGACCAAGGTCGGCATCCACCAAAGCAGTCCGTC	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP015612_11

>merge|NZ_CP015612|11|4317627-4317768|CRISPRCasFinder
CATCAAAAGCGCCGACCAAGGTCGGCATCCACCAAAGCAGTCCGTCAGTTCCGCAGGCCATCATGCACCCGGTAGGTGTCGACCTTGGTCGACACGCATCAAAAGCGCCGACCAAGGTCGGCATCTACCAAAGCAGTCCGTC

>NZ_CP015612|11|11|4317627-4317768|CRISPRCasFinder
CATCAAAAGCGCCGACCAAGGTCGGCATCCACCAAAGCAGTCCGTC	AGTTCCGCAGGCCATCATGCACCCGGTAGGTGTCGACCTTGGTCGACACG
CATCAAAAGCGCCGACCAAGGTCGGCATCTACCAAAGCAGTCCGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_005411372.1\|4321246_4322155_-\|aspartyl/asparaginyl-beta-hydroxylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|380241
NZ_CP015612.1\|WP_088027692.1\|4315597_4316257_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP015612.1\|WP_088027677.1\|4307262_4307745_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027683.1\|4310863_4314067_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027699.1\|4322588_4323248_+\|kinase	unknown	unknown	gnl\|CDD\|274749
NZ_CP015612.1\|WP_049400802.1\|4320273_4321128_+\|polyamine-aminopropyltransferase	unknown	unknown	gnl\|CDD\|234843
NZ_CP015612.1\|WP_088027687.1\|4314721_4315156_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379323
NZ_CP015612.1\|WP_088027694.1\|4316253_4317573_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|340430
NZ_CP015612.1\|WP_088027675.1\|4305927_4307136_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|334462
NZ_CP015612.1\|WP_005419983.1\|4325916_4326168_+\|accessory-factor-UbiK-family-protein	unknown	unknown	gnl\|CDD\|225508
NZ_CP015612.1\|WP_088027681.1\|4309415_4310855_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088022977.1\|4324416_4325382_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP015612.1\|WP_088028519.1\|4323489_4324014_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027690.1\|4315307_4315598_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225753
NZ_CP015612.1\|WP_088027697.1\|4318192_4320082_-\|arginine-decarboxylase	unknown	unknown	gnl\|CDD\|235427
NZ_CP015612.1\|WP_088027685.1\|4314211_4314580_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027701.1\|4326294_4326729_+\|NAD(+)--rifampin-ADP-ribosyltransferase	unknown	unknown	gnl\|CDD\|378815
NZ_CP015612.1\|WP_005411374.1\|4325422_4325761_-\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|366157
NZ_CP015612.1\|WP_088027696.1\|4317827_4318148_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027679.1\|4308335_4309391_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_005411372.1\|4321246_4322155_-\|aspartyl/asparaginyl-beta-hydroxylase-domain-containing-protein	gnl\|CDD\|380241	NF033391, lipid_A_LpxO, lipid A hydroxylase LpxO. Members of this family are LpxO, an enzyme that modifies one of the lipid chains in lipid A by hydroxylation, with resulting changes in resistance to the host immune response and to the antibiotic colistin. This family, as built, includes LpxO1 from Pseudomonas aeruginosa, but not its paralog LpxO2.	0
NZ_CP015612.1\|WP_088027692.1\|4315597_4316257_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.13597e-69
NZ_CP015612.1\|WP_088027697.1\|4318192_4320082_-\|arginine-decarboxylase	gnl\|CDD\|235427	PRK05354, PRK05354, biosynthetic arginine decarboxylase.	0
NZ_CP015612.1\|WP_088027699.1\|4322588_4323248_+\|kinase	gnl\|CDD\|274749	TIGR03724, Probable_serine/threonine-protein_kinase, Kae1-associated kinase Bud32. Members of this protein family are the Bud32 protein associated with Kae1 (kinase-associated endopeptidase 1) in the Archaea. In many Archaeal genomes, Kae1 and Bud32 are fused. The complex is homologous to the Kae1 and Bud32 subunits of the eukaryotic KEOPS complex, an apparently ancient protein kinase-containing molecular machine. [Unknown function, General].	3.9839e-13
NZ_CP015612.1\|WP_049400802.1\|4320273_4321128_+\|polyamine-aminopropyltransferase	gnl\|CDD\|234843	PRK00811, PRK00811, polyamine aminopropyltransferase.	1.95189e-146
NZ_CP015612.1\|WP_088027687.1\|4314721_4315156_-\|hypothetical-protein	gnl\|CDD\|379323	pfam13670, PepSY_2, Peptidase propeptide and YPEB domain. This region is likely to have a protease inhibitory function (personal obs:C Yeats). The name is derived from Peptidase & Bacillus subtilis YPEB.	2.30492e-11
NZ_CP015612.1\|WP_088027694.1\|4316253_4317573_+\|sensor-histidine-kinase	gnl\|CDD\|340430	cd16954, HATPase_PhoQ-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.	2.19383e-35
NZ_CP015612.1\|WP_088027675.1\|4305927_4307136_+\|FAD-binding-oxidoreductase	gnl\|CDD\|334462	pfam01266, DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.	4.43355e-41
NZ_CP015612.1\|WP_088022977.1\|4324416_4325382_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.05257e-28
NZ_CP015612.1\|WP_088027690.1\|4315307_4315598_+\|hypothetical-protein	gnl\|CDD\|225753	COG3212, COG3212, Predicted membrane protein [Function unknown].	2.72708e-12
NZ_CP015612.1\|WP_005419983.1\|4325916_4326168_+\|accessory-factor-UbiK-family-protein	gnl\|CDD\|225508	COG2960, COG2960, Uncharacterized protein conserved in bacteria [Function unknown].	4.98565e-21
NZ_CP015612.1\|WP_088027701.1\|4326294_4326729_+\|NAD(+)--rifampin-ADP-ribosyltransferase	gnl\|CDD\|378815	pfam12120, Arr-ms, Rifampin ADP-ribosyl transferase. This protein is found in bacteria. Proteins in this family are typically between 136 to 150 amino acids in length. The opportunistic pathogen Mycobacterium smegmatis is resistant to rifampin because of the presence of a chromosomally encoded rifampin ADP-ribosyltransferase (Arr-ms). Arr-ms is a small enzyme whose activity thus renders rifamycin antibiotics ineffective.	1.06796e-64
NZ_CP015612.1\|WP_005411374.1\|4325422_4325761_-\|P-II-family-nitrogen-regulator	gnl\|CDD\|366157	pfam00543, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	7.10063e-55
NZ_CP015612.1\|WP_088027679.1\|4308335_4309391_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.16889e-30

>NZ_CP015612.1|WP_088027694.1|4316253_4317573_+|sensor-histidine-kinase
MSRQPSLRRRLLLAGGAGLLLVSVLASALLGELFKRSARDRLDHELQQDMLTLLAQAEVDPEGQLRLRQEPNDARFQRVFSGAYWQIAGADGRVLLQSRSLWDETLPATAMGAATRNLAGPLQQSLRARVQQVRLPRASEPFVAVVATDRSALDADVAAFRKRTAIALGVLVAAWLAVLASQVHFGLRPLHRLGAQLERVRRGDAQRIDTQGLGAEVAPLGEELNALLEHQQRMVARARTSAQDLAHALKTPLSVLATEADSDGTHWRATVREQSARMQASVDRYLAAGLAADHRQRTNVATVAQALCRLMARVHGERGIAFTAADIDPALQFAGASADLEEMLGNLLDNAGRWAQQQVTVEAEISEGQLRIEVRDDGPGLAADALERVTQRGVRLDEREGSSGLGLAIVGDIAASYAGRVALENAQPGLRATLWLPVA
>NZ_CP015612.1|WP_088027692.1|4315597_4316257_+|response-regulator-transcription-factor
MRILLAEDDAALAQRLVPLLEQAGYVLHVVADGRQAEEIGQIEDLQAAIVDLGLPGLDGLSVIERWRGNGRSFPVLVLTARGRWHDKLAGFDAGADDYLTKPFQADELVLRLRALIRRSHGHASPRLHCGPLQLDINAGRFELDGQALSLSPQEFRLLSYFIHHSGQVIGRDRLGEQVFDGGLDPDSNALDVLLGRVRRKLGIDLIQTVRGQGWRLAAP
>NZ_CP015612.1|WP_088027690.1|4315307_4315598_+|hypothetical-protein
MLSTLPLLLALASSPTTAAPAQDPAQQVARRAVQQGRYVPLESVVRDALKRYPGQLLEVELDDGVYEVEILRGDGVVVELDYDARSGKLLKTELDD
>NZ_CP015612.1|WP_088027687.1|4314721_4315156_-|hypothetical-protein
MLKSLTLTTLAALAIAPAVQAAPLGMAQVEQTLRKAGYTQIHEIERDDGLWEADVSRADGRFSEVYVDPKTGEIFDEHSGRTLLTTEQVLARAQAHGLREIHSLERDGATWSLEARNARNQKVEVRLSGYDGRILHSERDGWLD
>NZ_CP015612.1|WP_088027685.1|4314211_4314580_+|hypothetical-protein
MEDLSPLLIAFNLLILLPLEVYALIRGINVQRYNLGIAKGRRYADGFWWRQATALARSRAAKGGNFLATVILASMGLAISLFSGAWLDTAICSYVLINALVAANFFAAQLPIIEAERREAGS
>NZ_CP015612.1|WP_088027683.1|4310863_4314067_+|hypothetical-protein
MNSIIEDTSMDVFHSSLDADEQRAVADLVERHRGNAAMTQRLALDASRLLTSSQDRLQKQAGAGFCKRLLGAISGSTRNNALANQHDTLKIQKIAWYYLQQLQQQNLINAQAIAVIRNNLGTMNEFIIETRCFLDEAIDRIGNRLRPLENNVRLNKWSLNIEANKRRYRSLPRSLLVVQLAYDFMLKHQDIELTLEDINHLVVTLENLGVNCDDEARLLDFIIDLIDQMDVTGIDLYRRNIQIVTEDIEIESAFIQSNISGIGFNALYYLSDQHSRIMALISDDELCNSDAAREKIISRIFGDEFDGLATTYTLRDLVAEIVGGGLLAIAIYRDINGLDVQADVFPPPEEQQEQISLVSRLPDIKQHSFLDAAEDADQRRTYIELLSLCLPDASECGPLGRDFINHLAAKADTPTAVSRFLSRDTRGHTQAEQLEELRVLLTDDNRVYCWLLDAFFLLSIEGRRIESPQVMRILGVLKPAQFKEQLAAIQSVLADEDHERVLQAGAQLSRLTAGWSNVLRYREFSLVDTFTDARRELHAASLAAINLSGDLSKAGMKAIDYSYFLGASPFDEGIFSKFTNAVGSTAFSVGRKSCASTLNQMRGKVVDLLATRAGALSSANALVSRFGLPIFDFENDSGYADFDLDNSAENEQWSDQFEHYQRRLEKTLDSFSSACDDADCQLGLFAEGDFSTPVLERRLRERELALQKQREKNLASRSAAVEKDGQVLLVSIDWEDITSPPCDPEQIRDMKTNGDRWLVATQEGRYYLSGDRVQWEEVHPFGVETTSTKNILVVSGTWILTGYSEGFAYSSDGRHWNRTSYPINEGDYSCSPTDDIVQFEGIWIWRFLRDCSYKYTKKGLVFDSEETGSYRETVLFATQSLDSPWSRWEGTPNLPEGMEVDALRALPGHHSLLIFCTYNWIYGNDKKKTELEPAVKYFVPGKGWRNCTWEGRMNQGSGVLVTRMADHLLCFGSNELFRATKAYEWSRDKDSISVRDAFHLESMSVFWHTSHSKLLLSQDGRTFADLTLEDGCWNYLCANDQGLLSVYSPNSHETWLRTGRWRVQPQH
>NZ_CP015612.1|WP_088027681.1|4309415_4310855_+|hypothetical-protein
MLITERNSMEDQTRKAVPAAVSVCPIWTGAAAEKVGQMIHQIDQSTTLMQRIASTAQNKAIKGGFAAEGWHAETFNLDAILKDKDVRAFTDTFSNSPLPRNHTTHDIVVMKGDEQLLGAQLKYFKDADATQKAFRSSKDGIHRYQDSDLFVGPSDQIEGIRQSAQRDVLKNQQTRPAVSEAAAKVRDRTAGSMEVDGAASTPLSKRDAEQLGTGSAEGKAAHKQMQDGYLNKATLQQSIRAAGSAALVTTVIAGSINTFQHLQHVRDGKITTEQAVHRILQNTVIAAGDAALKAGTATASVALATRAMPALFAGAGFNSVLARGGVAGAAVCAVDLVQCLVMVGVGRMTFAELETRTGTNILQTSAGVLGSSIGATLGMVGGPPGALVGGIIGGIIASMAMTIAVDNHVEKAFRLTLEGTREVVENGLSMQQSLELLQESQLFYADFHKGLVLSEKHFVGQITTLQAQSRQLREKLNRL
>NZ_CP015612.1|WP_088027679.1|4308335_4309391_+|WYL-domain-containing-protein
MSVDQKMSSRKKKDPTRRNVVLLRLIPRYPASISTVQLRDALLQEDPDFDISPRSLQRDLEGMLNGRFNLMCSKDHEDAAIRRKRPYRWSYEPHARAGAPVMSSAEALALCLSENHLRHVLPPDVMALLGPHFSDAHSRINGQISGGHGRWAQRVRSIPNGKSLLPAVVDGTVWNTVAEALLHQRQLQVDYLSRTKGESKRMTLHPKGLVSRGPASYLIASVSGYQDVRHFALHRIAQASLLDIRSDDDGFEMDHYLPGAAFTPRQGSGNIELIADIHPQLAWTLRETPLCEDQHLEALEATDWVRLHAHLPDDQENFWWLYSLGDNIRVLQPSGLREAILDRNQRVISLY
>NZ_CP015612.1|WP_088027677.1|4307262_4307745_+|hypothetical-protein
MIRPLTLLLCLALPGTVLAQSAAGATAPQATGLDLSLPQAPMRYLNDPTLQQDPPGTYYGDKSGPRVHDDARIADVTDDKVKVSGSFTTGIGYSKNGGNSHYNAATLNLSKNYTTDEGKTHGVNVNIHVSEGKGPGFFGPYGGYYGRGPGYWDYPPPFGW
>NZ_CP015612.1|WP_088027675.1|4305927_4307136_+|FAD-binding-oxidoreductase
MDLKSGYPWWAVRNGLIQAFPPLEKDLRCDVLVVGGGITGALIADELSRHGHDVAVIEQRDIGWGSSAASTALLQYEIDTHLLELAQRYGNDAAALAYHACAEAIPALGEVARGLKEVDFRQMDSLYLASRRRDVPRLMAEGAARRDIGLDARWLDREALRERFDVDAGGALLTRQAARVDPYCLTYGLLKRVRRRGGHVHDRTVLHTLKPGAQGVTAMTEAGATVRARHVVLAMGYANQRWLEQRVARNRSSYAFITDPIDADTLGRLQRTMVWESARPYLYLRATGDRRLLVGGLDDAIDIPARRDRRVQRKADKLMKQLLHWFPRLDPVPAFSWAGTFAETADGLPFFGPHAQWGPRVHFAMAYGGNGITYSMIGAQLLRVRIERRRHALEGLFGFERL
>NZ_CP015612.1|WP_088027696.1|4317827_4318148_-|hypothetical-protein
MSARAIFHLFLHAAVPALLAWLFWRKRFASAWLLMLLGWIIDLDHLLADPIYAPNRCSIGFHPLHTASAIAVYAGLCVPKKTRLVGIGLMIHIVLDAIDCWWMHHR
>NZ_CP015612.1|WP_088027697.1|4318192_4320082_-|arginine-decarboxylase
MTDWSLDQARKTYSIPHWADGYFDVDQAGHMVVRPTGADGPVVSLPKVVDAARAAGAKLPLLVRFPDILGQRLGKLQTAFGQAQQDWEYSGGYTAVYPIKVNQTRGVAGTLASHHGEGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGLQTFIVIEKPSELKLVLEESKALDVKPGLGVRMRLASLGAGKWQNSGGDKAKFGLSPRQLLDLWKSLRDTEYADCLNLLHFHMGSQISNVRDIANGMREATRYFVELSRLGAKITHVDVGGGLGVDYEGTRSRSFCSINYGLHSYASNIVQPLANACEEFGLTPPRIVTECGRAMTAHHAVLIANVSEVEEAQEGRVPDQHDDEPAAIRHLREIHDELDVRPAVELFQEAQHFHAEGLASYALGQIDLPQRARIDDLFYAIAHGVRARLSYDEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAIDQVFPIVPIERLDETPDRRGIIADMTCDSDGMVETYVENESLDSSLPLHKMKPGESYRIGFFMVGAYQEILGDIHNLFGDTDAVEVLADAEGYAITQQRRGDTTDVMLDYVGYRLDELRATYAQRVAEAQLSPERAQELSEALEAGLTGYTYLSDEPLV
>NZ_CP015612.1|WP_049400802.1|4320273_4321128_+|polyamine-aminopropyltransferase
MTDSNNWYIEHFERTGSAIGYRITGKLDEVQSPFQKIEIFQTTDWGNLMTIDGAIMLTSKDNFFYHEMISHPVLFTHAAPKRVVIIGGGDCGTLREVLKHTGVESVTQCDIDEQVTVMARKHFPELCDSNDDARAELLFDDGVAYMANCPAGSVDVVIVDSTDPVGPGEGLFNKAFYESCFKALKDDGILVQQSESPLMQLDLINEMRTEMGKAGFGSFKTLPFPQPCYPTGWWSVTMARKGDSSFDFRQADSAAKTFNTLYYTAALHTGVLVTPPFVQAALKG
>NZ_CP015612.1|WP_005411372.1|4321246_4322155_-|aspartyl/asparaginyl-beta-hydroxylase-domain-containing-protein
MIIKIVIAALFVACVLYIHFRGKVRARWSRQLLDHSSFMAPINVVMYMFSKVPTTPFLDPAKEFPQLEPLRQNWQMIRDEALALRDAQKIAASSTFNDAGFNSFFRRGWKRFYLKWYGPSHPSAKAMCPKTTALLESLPDVRAAMFAQLPSGSELRPHRDPFAGSLRLHLGLATPNNDGCYIEVDGIKKSWRDGEWMMFDETYIHHAHNETPDDRVILFCDIARPLRFGLPGLFNRAVAATLLAGGASPNLPGDPTGGVNKAFGSVYKVRLKAKALRERSVVAYQLIKWGLVVAVIAGIWAL
>NZ_CP015612.1|WP_088027699.1|4322588_4323248_+|kinase
MYLPALPPSCCGEDAATPLLLKRGERFLAPDVYRTCLDGREAVIKDYSRYRGTPVSLIARLMVRREAHILQRLGGWKHAPALLGTLGGLALGMEFIPGQTLSTAQAVGNDVFEQLQHALSRLHAAGITHNDLHGTNVVVSGGVPVLLDFTSAWRAPRWLRRNPLSRQMRRSDMKNLLKIRQRLTGQAPSAAQAALVADPGWVAAVRQGWKRFYKWAKRR
>NZ_CP015612.1|WP_088028519.1|4323489_4324014_+|hypothetical-protein
MVEFQPSAWDRGSYLNVGACWLWEEKDYLSFDVGGRVAGFERFTETAEFASAAQALAKQAAAEVLALRDRFPTPGHVRTLMSHHPKPGIREHIHAGITAGLAGAYDEGRRHLALAATETHPAPWVDVLKQRCAELMPLLQRDGGFEAEIAATVTRTRRALGLPEWRSSPLIPPG
>NZ_CP015612.1|WP_088022977.1|4324416_4325382_+|IS110-family-transposase
MQFIGIDAAKATFDIAVPLSGSKYRTKAKLPNTPKGFDELLAWRAKHAPNAAVGMEATGIYHEALARALVEAGVVVHVANPARVKAFGQAEGIRTKTDRSDAKLIARFFEAQRPEKLHPYVPPTPSEVKLRALVRRRDDLQEMLQMEHNRLDVADISVQQGIKDVIRTLEEQIKQVQKAIEDHIDNDPDLRRRHQLLTSIPGIGNTSSAQLLAMLGDLSKYSDVRQVVAHAGLNPAQRQSGNYEGKSRISRVGDAVFRKKLYMPALTGKTHNPTLKSFADRLSAKGKPFKVVMCAVMRKLIHLVWGVLRSGRPFEPDGALA
>NZ_CP015612.1|WP_005411374.1|4325422_4325761_-|P-II-family-nitrogen-regulator
MKMVMAVIKPFKLDDVREALAERGVTGITVTEVKGFGRQKGHTELYRGAEYVVDFLPKVKLEVAVTDDQVEAVVEAIVKAAGTGKIGDGKVFVYDLGSVVRIRTGELDADAL
>NZ_CP015612.1|WP_005419983.1|4325916_4326168_+|accessory-factor-UbiK-family-protein
MIDLNQIDDLARRLSDLVPPGLRESREELQATFKSALQAGLAKLDLVTREEFEVQRAVLLKTRQKLDALETAVRELEGRGAAE
>NZ_CP015612.1|WP_088027701.1|4326294_4326729_+|NAD(+)--rifampin-ADP-ribosyltransferase
MAQDTEWTPISHDTCDQVAGPFYHGTRADLAVGELLSAGFRSNYRDSVVMNHIYFTTIAKGAGLAAEMARGEGRPRVYVVEPTGPFEDDPNVTNKKFPGNPTRSYRSAQPLRVVGEIVEWELYDAEFVRQLKAFVASGSGEIIN

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Crispr_ID: NZ_CP015612_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015612_12

4342714-4342835

Orphan

Consensus_repeat	Method
GGCGCTTGCCGTCTACGTGTGCCAACCAAGGTTGGCACCTACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015612_12

>merge|NZ_CP015612|12|4342714-4342835|CRISPRCasFinder
GGCGCTTGCCGTCTACGTGTGCCAACCAAGGTTGGCACCTACCGGGGTCTGTGAGGCATGGTAGAGGCCGACCTTGGTCGGCGCTTGCCGTCTGCGTGTGCCAACCAAGGTTGGCACCTACC

>NZ_CP015612|12|12|4342714-4342835|CRISPRCasFinder
GGCGCTTGCCGTCTACGTGTGCCAACCAAGGTTGGCACCTACC	GGGGTCTGTGAGGCATGGTAGAGGCCGACCTTGGTC
GGCGCTTGCCGTCTGCGTGTGCCAACCAAGGTTGGCACCTACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015612.1\|WP_005411473.1\|4349993_4350326_-\|cytochrome-o-ubiquinol-oxidase-subunit-IV	unknown	unknown	gnl\|CDD\|131894
NZ_CP015612.1\|WP_088027739.1\|4345931_4346372_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226695
NZ_CP015612.1\|WP_088027737.1\|4344628_4345939_-\|sorbosone-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|225044
NZ_CP015612.1\|WP_088027711.1\|4329391_4329922_+\|cold-shock-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027729.1\|4340121_4342440_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NZ_CP015612.1\|WP_088027723.1\|4337203_4337416_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_049400824.1\|4346682_4348449_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173789
NZ_CP015612.1\|WP_088027725.1\|4337879_4339382_+\|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl\|CDD\|223679
NZ_CP015612.1\|WP_088027733.1\|4342854_4343688_-\|sugar-phosphatase	unknown	unknown	gnl\|CDD\|182509
NZ_CP015612.1\|WP_088027715.1\|4331383_4332430_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|275256
NZ_CP015612.1\|WP_088027727.1\|4339570_4339831_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_088027721.1\|4335774_4337067_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|274576
NZ_CP015612.1\|WP_088027716.1\|4332445_4334518_-\|peptidase-domain-containing-ABC-transporter	unknown	unknown	gnl\|CDD\|225183
NZ_CP015612.1\|WP_088027741.1\|4348448_4349042_+\|DNA-breaking-rejoining-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_157664608.1\|4337522_4337852_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015612.1\|WP_005414759.1\|4350327_4350963_-\|cytochrome-o-ubiquinol-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|131889
NZ_CP015612.1\|WP_088027736.1\|4343837_4344500_+\|exopolysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|368723
NZ_CP015612.1\|WP_006474876.1\|4350959_4352936_-\|cytochrome-o-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|131890
NZ_CP015612.1\|WP_157664607.1\|4334542_4335778_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|274576
NZ_CP015612.1\|WP_088027743.1\|4349178_4349850_-\|SCO-family-protein	unknown	unknown	gnl\|CDD\|239266

Protein	Function_ID	Function_description	E-value
NZ_CP015612.1\|WP_005411473.1\|4349993_4350326_-\|cytochrome-o-ubiquinol-oxidase-subunit-IV	gnl\|CDD\|131894	TIGR02847, Cytochrome_bo3_ubiquinol_oxidase_subunit_4, cytochrome o ubiquinol oxidase subunit IV. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	3.92143e-34
NZ_CP015612.1\|WP_088027739.1\|4345931_4346372_-\|hypothetical-protein	gnl\|CDD\|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	4.57115e-12
NZ_CP015612.1\|WP_005414759.1\|4350327_4350963_-\|cytochrome-o-ubiquinol-oxidase-subunit-III	gnl\|CDD\|131889	TIGR02842, Cytochrome_bo3_ubiquinol_oxidase_subunit_3, cytochrome o ubiquinol oxidase, subunit III. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	8.23598e-101
NZ_CP015612.1\|WP_088027729.1\|4340121_4342440_-\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	4.72205e-23
NZ_CP015612.1\|WP_049400824.1\|4346682_4348449_+\|S8-family-serine-peptidase	gnl\|CDD\|173789	cd04059, Peptidases_S8_Protein_convertases_Kexins_Furin-like, Peptidase S8 family domain in Protein convertases. Protein convertases, whose members include furins and kexins, are members of the peptidase S8 or Subtilase clan of proteases. They have an Asp/His/Ser catalytic triad that is not homologous to trypsin. Kexins are involved in the activation of peptide hormones, growth factors, and viral proteins. Furin cleaves cell surface vasoactive peptides and proteins involved in cardiovascular tissue remodeling in the TGN, at cell surface, or in endosomes but rarely in the ER. Furin also plays a key role in blood pressure regulation though the activation of transforming growth factor (TGF)-beta. High specificity is seen for cleavage after dibasic (Lys-Arg or Arg-Arg) or multiple basic residues in protein convertases. There is also strong sequence conservation.	8.5757e-102
NZ_CP015612.1\|WP_088027736.1\|4343837_4344500_+\|exopolysaccharide-biosynthesis-protein	gnl\|CDD\|368723	pfam06055, ExoD, Exopolysaccharide synthesis, ExoD. Among the bacterial genes required for nodule invasion are the exo genes. These genes are involved in the production of an extracellular polysaccharide. Mutations in the exoD result in altered exopolysaccharide production and defects in nodule invasion.	4.6821e-43
NZ_CP015612.1\|WP_088027733.1\|4342854_4343688_-\|sugar-phosphatase	gnl\|CDD\|182509	PRK10513, PRK10513, sugar phosphate phosphatase; Provisional.	3.13263e-176
NZ_CP015612.1\|WP_088027715.1\|4331383_4332430_-\|radical-SAM-protein	gnl\|CDD\|275256	TIGR04463, Radical_SAM_domain_protein, radical SAM/SPASM domain protein maturase. Members of this family are probable protein/peptide-modifying radical SAM/SPASM domain proteins. The majority of members of this family seem to target Cys-rich repetitive regions of large proteins rather than of bacteriocin-sized small precursors. This arrangement suggests the modification target may be multifunctional, with the C-terminal domain behaving like a bacteriocin but other parts of the same precursor serving an immunity function, as occurs for the halocin C8 precursor.	5.99605e-34
NZ_CP015612.1\|WP_088027721.1\|4335774_4337067_-\|ABC-transporter-permease	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	3.92681e-20
NZ_CP015612.1\|WP_088027716.1\|4332445_4334518_-\|peptidase-domain-containing-ABC-transporter	gnl\|CDD\|225183	COG2274, SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].	1.83415e-136
NZ_CP015612.1\|WP_088027725.1\|4337879_4339382_+\|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP015612.1\|WP_088027737.1\|4344628_4345939_-\|sorbosone-dehydrogenase-family-protein	gnl\|CDD\|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	5.71599e-96
NZ_CP015612.1\|WP_006474876.1\|4350959_4352936_-\|cytochrome-o-ubiquinol-oxidase-subunit-I	gnl\|CDD\|131890	TIGR02843, Cytochrome_bo3_ubiquinol_oxidase_subunit_1, cytochrome o ubiquinol oxidase, subunit I. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	0
NZ_CP015612.1\|WP_157664607.1\|4334542_4335778_-\|FtsX-like-permease-family-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	1.47621e-19
NZ_CP015612.1\|WP_088027743.1\|4349178_4349850_-\|SCO-family-protein	gnl\|CDD\|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	1.4692e-50

>NZ_CP015612.1|WP_088027729.1|4340121_4342440_-|TonB-dependent-receptor
MNTPPTTRLALAIITAIAAPAYAAETHDAAHDSPTTLNALQVIATPRGAAVAPTQVVGPNRYIIKAEDLDAMATGNNGLAMLKQVPGASYTATDGLGLDISATSLFVRGFRMNEMGITFEGVPLNDNGFLSLTGTSVVNVGVPDGIGAITVSPGGAPVSVFSSSVNGGSLEYRLRELQDTPSLRVKQGVGSNNTLVTTVSGQTGQLGEYGPKVLVDLQRVSADKYQGEGTQNFLRGDLKLQQDVAWGDVTVFLSDSKAKVWGYNNISFDMIRKLGWKADIFYPDYAWAWYVASPENADKSCGAYTCGELSELIPYDTGQTTRDRVSSINHRFQITPALSGNVQLYNANSHTQATLTDPTVPSPNGAPFSEQVQTPRLNRQGGMVNLQFETGAHTFTAGFWQEKSKAAAKTEWYQQPLLGEGPPLKATGPFDVYGPAFKTDNASSWVTRSRQFYLQDDIVLNDTLKLGVGFKAVDFRTSGGGLGDAKDRPVNGTLRAKSNFLPHVSLFWSPTESTDAFIDLANTMNGYRVAQRGNIGYTASAWTITDQEEFDRVAGTLRPEKNWNLTVGASHRFDRLTITGDVFYNDIRNRLLSAAIGTQFAQINTVRLMPKMHVIGADLGITADLTDHLQFYQGVAVARSYYDSDFVVGDTVYPIKGNAQPGYPQISLVSDLSAHFGDWRFGATSTSYLRQPFTYENDIRVPTFWQVNTYAAYRFGADSAVPGLELRLDVSNLFNRHNIGTATIAGSSFSGDYQTLQRSAPRQLMFSTSMAF
>NZ_CP015612.1|WP_088027727.1|4339570_4339831_+|hypothetical-protein
MKKLIMVAALLLLTASISGTAFGAILQIQGFGSGLSQSQATQIAASNASNQCAIQGGHSVGFFHVTMATQNGPTWFVNGVLPCDVP
>NZ_CP015612.1|WP_088027725.1|4337879_4339382_+|YifB-family-Mg-chelatase-like-AAA-ATPase
MSLALVHSRARAGVDAPLVRVEVHLSGGLPVTQIVGLAETSVRESRERVRAALLCARFDFPQRRITLNLAPADLPKEGGRYDLAIALGILAASGQVDPQSLLQYEFLGELGLTGELRPVAGALPAAIAAAEAGRILVVPPGNAAEAALAEHADVRVARTLLECCAGLGNPRLLPPVERVDTTPLPLPDLADVRGQAHARRALEVAAAGGHHLLLIGSPGCGKTLLASRLPSLLPDTEETEALQQAAIASVSCEGLDPRRWRQRPFRAPHHSASAAALVGGGNPPCPGEISLAHHGVLFLDELPEWNRSALETLREPLESGHIRIARAARSVQYPARFQLVAAMNPCPCGWAGDRSNRCLCSDERINRYRARVSGPLLDRIDLHISVTRMDAVELRESTPLGEPSAAVRARVEAAHARQQARGELNAHLLPAALRACTKLSEADQDLLEQAIERLQLSARAMHRILRVARTIADLADYETIQTAHLAEAIGYRQLDRALQP
>NZ_CP015612.1|WP_157664608.1|4337522_4337852_-|hypothetical-protein
MVRYVTCSGLSGIGVEVAKKIPINPGPVRLVMSVRPMPLSSLELLVCAATGFVIATSAGETVIGGEFWHSFRTRQGRIERLRTPHDVFGRTSLLPSAVTTLSHTRRRRI
>NZ_CP015612.1|WP_088027723.1|4337203_4337416_+|hypothetical-protein
MDAAGSEQFNGTWITHFAKAVFVIDEWITIFATLFQLVHVISLVLLLPTSDSLVRGDLPEFGKFDASVRE
>NZ_CP015612.1|WP_088027721.1|4335774_4337067_-|ABC-transporter-permease
MRYALQLALLGIGRSWLLSLLIVASLAIGISAFATMLMIRMGLSADPAPAVSRTLYHVELDLRDSSSRESDNRRIPTLALYDVKALSDRTGVPSVATSSSWLPYRSYGSERRAGMLPVRGFTYGAQSVLDLNLISGSFWRREDDDAGSRVAVISRSLSRELFGTESALGKELELATRSFVIVGIVEDWNPAPRFHDLRGGAYTDNERLYIPLSSWIALPTDYGMGGMTCRKGVLDDPNHPSCAWLQFWVRLEGASTLDAFRVALKNYAEEQVEGGRSTHAYPNVMSLLEWLKINDVVPEDVHTQLWFAVGILIICLVNASGLFLAGFVDNARETGIRRSLGATRRDVVMQFALQSTMLGTLGGVLSVPLVLVGFHIVKGLAPEHSAHLSLPVWLLLLCPVIALLSAMLSAAVPVWRTSRLPASLLTGEAR
>NZ_CP015612.1|WP_157664607.1|4334542_4335778_-|FtsX-like-permease-family-protein
MMFISSAAMTMRSLRKHAAIATLLIVQVAIAMAVLCNLFTVVLDASQRSRTHSGLSESHIAVVQNIGIIGLEEDATSSAAGLRAMRAVPGITMAAIGPAPFAVERGDVYLEPSRELSVARPYIYFGSESLSDTLGVSVLQGVGLRTLRAPAVGDALQAGGSLHVPAVVTSSLSKRLFPAGNPLGQIIHAEVWGSYPIALRIVGVVTDFRSASTRSPSDSDAVIAEVKIESESIGGLYVARRSASFDHRGKQGLLTALSLSMPGFVQEPVRTVAELRVRNFRKDVARSQVLLLVATIVTVSSALGVFGLTHFWVSRRRWSTAIRRALGASRRDVVVLFATESALISSIGVLAGMGLAILMNLLLGRQVELVPVSGLAMAAGAGVTFFGCSVAAIIPAFSAAKVEPALAFRLR
>NZ_CP015612.1|WP_088027716.1|4332445_4334518_-|peptidase-domain-containing-ABC-transporter
MLTFWTRWKRRRVDVVLQSESTECGLACLAMVASRYDKRITLRWLRRRYMVSLRGTTVGRISQIACELGLQHRVFAGQATALRSIESECILLVDGGHFVVMQRVSPERFTLLDPAAGEIAVSFAELERRFSGALLMFTGGRRQCEEFAVEVSPWQTLASQVRQQKHRYLPIVLLAIAAEILLVVSPLYLQTIIDGLQIADAAFNPERLLVIFVAIAAARVLAVASRSMLTVKLGANIIGALSTKVFGKILSLPPAYFLRRHPADVISRLSSVHEVQEIASSKIVECSIDSIALLILLVACWFHSSLLAALAVAGVIACVLVRVFMSDDAGVACNVLASRLSSQDREVIETVRAAQTVKANGAERAREIRFRESNVGLINASTSLQRISIASSCTSDLILGLTRIAVVYMGALAVQEGSMSIGALVAVAIYVEMLGQRASSIVPKVMDIRMARTHLHRISEVLSGAEEERTPWEVAGSHRDSLSIGCRDIGFRYSIDDPWVIRGLNVNIEAGEMVAIVGPSGVGKSTLLRILTGLIPPTEGVMEIDGRGVERGQIANLRSHIGTVLQQDTLLSGTVLDNVTLGEVVNVDEAWSCLSAAGLDAFVAEQPMSLGTQVGDEGRLLSGGQQKRLLLARALYRSPKILVLDETLSQLDYEAEQQILATLLALKMTRVIVTHRVRALPEDVRVIRLG
>NZ_CP015612.1|WP_088027715.1|4331383_4332430_-|radical-SAM-protein
METFQERLNKRLELTIMPTEKCNFRCVYCYEDFEIGRMRAPTIKGIKALVRRRVEEHGLKELRVEWFGGEPLLAKMVVLELSRAFHAHHSSGALDLLDCSMTTNGYELTPELFNELVGLGVNFFQISLDGDASAHDVTRRYASGAGTFQRIYENLLAMRESPLIFTVMLRVHIMPGNEGSLRDLSSRLWSDFGGDQRFTIYLRDISNLGGQGQSLELISHAEAVRISRELQAKFEGEGFRVENGVETEFESQVSISGLSDSNAELQAMSMSGLRVSHVCYAAKPNHMLIRADGRIGKCTVALASEGNVVGALAEDGTVALDPARMKFWTRGFLSGDATELGCPLMTRS
>NZ_CP015612.1|WP_088027711.1|4329391_4329922_+|cold-shock-protein
MKMHGLAAAAVCIEVIGAMWVEWPEPAGDQVWAYQKLRPADYRLLHSDALGFVTAKAHDGFELHARHAGATSFEIRCKGVLVMDVENAPSRVLIRMPADARWRAPDIERLRISFERWLDLHQSQGRLLVESAGHSWVEARFGRFNGLVLDEQRCLLGSPGHRQAVPTNHVRAGVPS
>NZ_CP015612.1|WP_088027733.1|4342854_4343688_-|sugar-phosphatase
MDMGRRQSTIELVAIDMDGTLLDPTHTLTVRAKQAIAQARALGVHIVLTSGRPVPGLEPFLHELGITGDDDYCIACNGGLVQRIGTRETVVEYPLSFDDFLFCEQVARDLGVHFQALDSQRMYTPNQDISYYTVADSHLSRMPLSYRRVADMDPSMSFIKLMMIDAPDVLDAAIARLPTELTERFAVLKSAPFFLEVFDHRAGKGPSLQKLAEHLGIDRANVMAIGDQENDLTMLQYAGTSVAMGNAIDAVKAVARFETTSNADEGVARAIERFVLQ
>NZ_CP015612.1|WP_088027736.1|4343837_4344500_+|exopolysaccharide-biosynthesis-protein
MTYRAPETNDSAPLAQQIEQMIDELPGDQVSVGTLLSALGDEGLLLIVILLSAIFIIPVSIPGLSTVFGASILLIGLSRVRNRPLWVPQKLARREIATDKLKANLGRALKWVHRMERLSRPMRLAVMVRSKKMMRLNNLMLVFATLLLMAPAGPIPFSNTLPALALMSFAIGFIQRDGAAVAAGYGFVVATVVYFGALLGGVGFAAESVFSGLRAAPSEV
>NZ_CP015612.1|WP_088027737.1|4344628_4345939_-|sorbosone-dehydrogenase-family-protein
MAKHILPTVAALALAVMLSACAGKAEYHPTDQSGAKPPLPAPKNFLMPPMQVPRGVGWAEGQSPTVAEGLKIERIAANLQHPRRLLTLPNGDVLVVEGNGPGEEPVTTPKQWIAGKVKARSGKAGKGGNRVTLLRRAPGTSTWTQHVYIEGLHSPFGIQLIGDTLYVANTGNIVQYHYVPGETRMSDKGREFTDLPSTINHHWTKELLASRDGSKLYVGVGSNSNITENGLAVEYRRAVVLEVDVATRGSRIFASGIRNPTGLDWEPSTGKLWAVANERDEIGADLVPDYLTSVKEDGFYGWPYSYYGQHVDERVQPQRPDLVAKAITPDYAIGSHVAPLGLLFYTGQALPAQYHGGAFIGEHGSWDRSPLSGYEVVYVPFKDGKPTGRPQTVVSGFASKDEKTLMGAPVGMAMDAEGALLVADDVGDVVWRVSAK
>NZ_CP015612.1|WP_088027739.1|4345931_4346372_-|hypothetical-protein
MVNPLAQAHRGLGTTLFSLLNPIPFGFFVGALIFDAIYLNSAEVMWGKAAAWLITFGLLIAIIPRLINLFTVWRRNGTATRVDRIDFFLNLVAVVLAIWNAFVHSRDAYAVAVPGTILSALTVALIALGLILLSLQPPVLQGGRHG
>NZ_CP015612.1|WP_049400824.1|4346682_4348449_+|S8-family-serine-peptidase
MKRHTQRSAPPRSARLALATALVLGSLAVTAQAQQADPLAGRQWHLLNTGQAVLGDTLPVAGNDLNVDGLFRNGIRGQGVTIAIVDDGLQIAHPDLAANVAAVAGKNFANQSNNPSPSNPDRDNHGTMVGGIAGAVGANNLGVRGVASAATLKGFNFLASNAQGNSNSNIEYSWWDGAEVADVGVFNNSWGSSPGNPNLPLAYSQNDIAAYEQAMSGTRGGRGGIYVKAAGNNHNNGARSDGTDICSADTKNRNTGCIPAGRDPRNNLFNVITVAAVRADGVRSSYSSTGSALWVSGFGGENGWQRQVVPGQLAIRYDPAILTTDVTGCAQGSNKNTSLRNTLDGDQSAIDSTCNYTGKMNGTSAATPMVSGVAALLLETNPNLSYRDVKYILATTATRTDPNRAAVTHSDGRVLVPGWTVNAAGRAYSNWYGFGVVNAARAVQVAEDFQPLGALVDSGWRNTTRTVAIGNTSAAAARLTFQLANGARNIESVQLGFRVNHSNTRQLQFVLISPSGTRSVVQPAFTAIGSGLNGVQRNFTNWDLLSSNAFLDENATGTWTLEVTDLGQAANAASRGNLEFFKIRVLGH
>NZ_CP015612.1|WP_088027741.1|4348448_4349042_+|DNA-breaking-rejoining-protein
MMKTTILLSTLALAAMTTTAWAQSSGQTPPAKTLSTVDTQQLKAEATGRSFNVGGSRFQLAPSATVQQASGGQFRITTGADASAAAVGTRSKRSTDASTGVAARADAGASKFAAAVSNDGAPVVATSRVKVFFTDAASAQRAAIATGGTVVKVSKASGRAIVEYPSVNAALDATTKLLSTAGIKAAEPDVVQWEETK
>NZ_CP015612.1|WP_088027743.1|4349178_4349850_-|SCO-family-protein
MFSPRFRLPLLAGLAIGLLAGCSAQSRMDFYSGDIACEELGQQWSMPDSHGTVRGPKDLQGQVTYLFFGFTSCPDVCPTTMVELSQVKHLMGKDADQLQVVFVSVDPARDTPEVARTYVEAFDPKAIALVGNEAQLAAMASDFKAFYEKEPGQVPETYTMSHIAGGYVFDRQGRLRLFAPYGMPVDKLFSDVQRLLLEPAHPAAGNDALASCSRKHSDTLAAR
>NZ_CP015612.1|WP_005411473.1|4349993_4350326_-|cytochrome-o-ubiquinol-oxidase-subunit-IV
MAHVETSRAGNAHGSTKSYLIGFVLCALLTVVPFALVMNPVLSRPLTLFLLVGFAVAQILVQLVYFLHMDRKSEGGWNLASFVFTLVILFIIVALSVWIIWSMHYHMMIN
>NZ_CP015612.1|WP_005414759.1|4350327_4350963_-|cytochrome-o-ubiquinol-oxidase-subunit-III
MNLLTRPELASDTQAHEDHHEHDHGHEQGGMKVFGMWVYLMSDLVLFGSLFASYAVLSTAYAGGPTGKELFSLPFVMAETFLLLVSSITYGQAVLAMHRHDTSAVLRWLGVTFVLGASFIGMEIYEFSHLIHEGAGPSTSAYLSAFFALVATHGLHVASGLIWMAVVMHQVYRRGLTPTNITRVSCLSLFWHFLDLVWICVFTFVYLIGAF
>NZ_CP015612.1|WP_006474876.1|4350959_4352936_-|cytochrome-o-ubiquinol-oxidase-subunit-I
MLGKLTWEAVPLHEPIVVVTLAAMVLGGLALLGAVTYFKLWGPLWRDWFTTVDHKKIGIMYVVVALVMLVRGFADALMMRAQLAAAGPGSDGFLPPEHYDQIFTAHGVIMIFFVATPFVVGLMNIIVPLQIGARDMAFPFLNAFSFWIFVVGAALMMISLGVGEFAMTGWVAYPPLSGIEFSPGVGVDYYIWALQASGIGTLLTGVNLFITILRMRAPGMTLMKMPVFTWTVLVTSVIIIAAFPILTVALGALTLDRYLDFNFYTNTLGGNPMMYVNLVWAWGHPEVYILVLPAFGIFSEVTATFARKKLFGYKSMVGATLAIGILSFIVWLHHFFTMGSGASVNAFFGIMTMIIAIPTGVKIFTWLFTMYGGRVEFSVPMLWTIAFLVTFTIGGMTGVLLAIPGADFLLHNSLFLVAHFHNTIIGGALFGYLAGFAYWFPKVFGFTLNERLGKWSFACWVIGFYLAFMPLYMLGFMGMTRRMNQYDNPAWTPYLIAAFIGALFVFAGIILMLVQIYVSVRDRKRNLDLTGDPWNARTLEWATPSPPPFYNFAVVPKADELDAFHEAKKRGLPPPPKKYAPIHMPKNTGVPLILNIWILVLCFALVWHIWWMAAASFIAMIVTLIVRSYDEDVDYYVSSEEVARTEAANLAKLKEVRA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	NZ_CP015612.1	1037562-1037590	1	0.966
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	NZ_CP015612.1	1399170-1399198	1	0.966
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	NZ_CP015612.1	1922831-1922859	1	0.966
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	NZ_CP015612.1	3152472-3152500	1	0.966
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	NZ_CP015612.1	2965616-2965644	2	0.931

1. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to position: 1037562-1037590, mismatch: 1, identity: 0.966

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
cagtagatccacgccatgcgtggatgaac	Protospacer
************************** **

2. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to position: 1399170-1399198, mismatch: 1, identity: 0.966

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
cagtagatccacgccatgcgtggatgaac	Protospacer
************************** **

3. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to position: 1922831-1922859, mismatch: 1, identity: 0.966

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
cagtagatccacgccatgcgtggattcac	Protospacer
************************* ***

4. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to position: 3152472-3152500, mismatch: 1, identity: 0.966

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
cagtagatccacgccatgcgtggatccac	Protospacer
************************* ***

5. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to position: 2965616-2965644, mismatch: 2, identity: 0.931

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
cagtagatccacgcgatgcgtggatacac	Protospacer
************** **********.***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015612_4	4.1\|1108330\|29\|NZ_CP015612\|CRISPRCasFinder	1108330-1108358	29	NZ_CP044066	Cupriavidus pauculus strain FDAARGOS_664 plasmid unnamed1, complete sequence	109509-109537	6	0.793
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	MH791411	UNVERIFIED: Escherichia phage Ecwhy_1, complete genome	27642-27670	9	0.69
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	MT446416	UNVERIFIED: Escherichia virus TH47, complete genome	174927-174955	9	0.69
NZ_CP015612_7	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	MH494197	Escherichia phage CMSTMSU, complete genome	210430-210458	9	0.69
NZ_CP015612_3	3.1\|758438\|34\|NZ_CP015612\|CRISPRCasFinder	758438-758471	34	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	1046362-1046395	10	0.706
NZ_CP015612_3	3.1\|758438\|34\|NZ_CP015612\|CRISPRCasFinder	758438-758471	34	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	1416362-1416395	10	0.706

1. spacer 4.1|1108330|29|NZ_CP015612|CRISPRCasFinder matches to NZ_CP044066 (Cupriavidus pauculus strain FDAARGOS_664 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

ataggaattcaccttgaactgcctgggtg	CRISPR spacer
ataggagttcgccttgaactgccagcctc	Protospacer
******.***.************ *  *

2. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to MH791411 (UNVERIFIED: Escherichia phage Ecwhy_1, complete genome) position: , mismatch: 9, identity: 0.69

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
ttacagatccacgctatgcgtggattttt	Protospacer
. ..**********.********** . .

3. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to MT446416 (UNVERIFIED: Escherichia virus TH47, complete genome) position: , mismatch: 9, identity: 0.69

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
ttacagatccacgctatgcgtggattttt	Protospacer
. ..**********.********** . .

4. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to MH494197 (Escherichia phage CMSTMSU, complete genome) position: , mismatch: 9, identity: 0.69

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
ttacagatccacgctatgcgtggattttt	Protospacer
. ..**********.********** . .

5. spacer 3.1|758438|34|NZ_CP015612|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 10, identity: 0.706

tctttcccgcatccacgcgtggcgtggatctacc	CRISPR spacer
tctttcccgcacccacccgtggcgcacgcagatc	Protospacer
***********.**** *******.. ..  *.*

6. spacer 3.1|758438|34|NZ_CP015612|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 10, identity: 0.706

tctttcccgcatccacgcgtggcgtggatctacc	CRISPR spacer
tctttcccgcacccacccgtggcgcacgcagatc	Protospacer
***********.**** *******.. ..  *.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

575867 : 588375

Enterobacteria_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088024053.1\|575867_577226_-	phosphomannomutase	A0A127AWJ1	Bacillus_phage	2.4e-31	26.8
WP_088024056.1\|577360_578302_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_057500379.1\|578301_579048_-	electron transfer flavoprotein subunit beta/FixA family protein	NA	NA	NA	NA
WP_088024058.1\|579306_580362_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	9.2e-79	45.6
WP_088024061.1\|580376_581264_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.7e-97	59.2
WP_088024064.1\|581260_581818_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	9.9e-48	51.1
WP_088024067.1\|581814_582720_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.8e-30	38.6
WP_088024070.1\|582889_586216_-	DEAD/DEAH box helicase	Q9YNZ9	Choristoneura_fumiferana_nuclear_polyhedrosis_virus	1.3e-46	29.9
WP_012509993.1\|586376_587108_+	CoA transferase subunit A	NA	NA	NA	NA
WP_088024075.1\|587109_587742_+	CoA transferase subunit B	NA	NA	NA	NA
WP_088024080.1\|587787_588375_+	alpha-ketoglutarate-dependent dioxygenase AlkB	A0A2K9L0M4	Tupanvirus	2.8e-24	34.3

DBSCAN-SWA_2

974741 : 1064461

Escherichia_phage(18.52%)

plate,integrase,tail

attL 956609:956637|attR 1037565:1037593

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
956609:956637	attL	NA	NA	NA	NA
WP_088024699.1\|974741_975980_+\|integrase	tyrosine-type recombinase/integrase	A0A077KET4	Ralstonia_phage	1.6e-53	37.2
WP_088028257.1\|976203_977103_+	hypothetical protein	NA	NA	NA	NA
WP_157664567.1\|977987_978161_+	hypothetical protein	NA	NA	NA	NA
WP_083298676.1\|978631_979690_+	catalase family protein	NA	NA	NA	NA
WP_049452914.1\|979714_980410_+	hypothetical protein	NA	NA	NA	NA
WP_049452916.1\|980411_981788_+	Dyp-type peroxidase	NA	NA	NA	NA
WP_088024700.1\|981743_982460_-	conjugal transfer protein traA	NA	NA	NA	NA
WP_070470389.1\|982843_983209_+	conjugal transfer protein TraD	NA	NA	NA	NA
WP_083298674.1\|983413_984760_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_043033702.1\|985234_986473_+\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	6.6e-52	37.0
WP_088028259.1\|986711_987623_+	hypothetical protein	NA	NA	NA	NA
WP_088024702.1\|987719_995411_+	AAA family ATPase	F2NZ48	Diadromus_pulchellus_ascovirus	5.4e-27	31.2
WP_088024704.1\|995519_996803_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_046429154.1\|996965_997271_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_088024705.1\|998063_999020_+	DUF932 domain-containing protein	A0A0H4INH5	Stenotrophomonas_phage	6.0e-61	42.9
WP_046429159.1\|999016_999394_+	hypothetical protein	NA	NA	NA	NA
WP_088024707.1\|999465_1000452_+	endonuclease	A0A139ZPJ9	Marinitoga_camini_virus	9.3e-49	46.7
WP_088024709.1\|1000463_1001360_+	hydrolase or metal-binding protein	NA	NA	NA	NA
WP_088024711.1\|1001458_1001956_+	DNA repair protein RadC	NA	NA	NA	NA
WP_088028261.1\|1002139_1003552_-	ADP-ribosylglycohydrolase family protein	A0A1V0SCE0	Indivirus	1.3e-08	38.2
WP_088024713.1\|1004176_1005088_+	WYL domain-containing protein	NA	NA	NA	NA
WP_088024715.1\|1005084_1008012_+	DEAD/DEAH box helicase	A0A2H4J643	uncultured_Caudovirales_phage	2.1e-266	50.5
WP_088024717.1\|1008047_1011167_+	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	9.5e-15	25.4
WP_088024719.1\|1011166_1014562_+	type III restriction endonuclease subunit R	NA	NA	NA	NA
WP_088024721.1\|1014614_1016450_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_088024722.1\|1016539_1018006_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_088028263.1\|1018002_1018341_-	hypothetical protein	NA	NA	NA	NA
WP_088024724.1\|1018938_1020993_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	2.1e-47	41.4
WP_005408298.1\|1020999_1021320_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_088024726.1\|1021431_1022031_+	recombination protein RecR	NA	NA	NA	NA
WP_014036181.1\|1022098_1022458_+	histidine triad nucleotide-binding protein	NA	NA	NA	NA
WP_088024728.1\|1022546_1023074_-	hypothetical protein	NA	NA	NA	NA
WP_088024730.1\|1023070_1025020_-	DUF3488 domain-containing transglutaminase family protein	NA	NA	NA	NA
WP_088024732.1\|1025012_1025957_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_088024734.1\|1025959_1026913_-	AAA family ATPase	NA	NA	NA	NA
WP_088024736.1\|1026955_1028791_+	hypothetical protein	NA	NA	NA	NA
WP_088024738.1\|1028887_1029457_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_088024741.1\|1029570_1030080_+	hypothetical protein	NA	NA	NA	NA
WP_004154640.1\|1030187_1030382_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_014646186.1\|1030473_1031451_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_088024743.1\|1031528_1032311_+	serine/threonine protein phosphatase	NA	NA	NA	NA
WP_088024746.1\|1032471_1033416_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_088024747.1\|1033498_1034242_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	6.2e-13	32.3
WP_005408313.1\|1034394_1034634_+	acyl carrier protein	B2ZXV3	Ralstonia_phage	4.6e-10	44.6
WP_004146925.1\|1034777_1036040_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_088024749.1\|1036132_1037497_+	aminodeoxychorismate synthase component I	NA	NA	NA	NA
WP_088024751.1\|1037716_1038778_+	endolytic transglycosylase MltG	NA	NA	NA	NA
1037565:1037593	attR	NA	NA	NA	NA
WP_088024753.1\|1038774_1039440_+	dTMP kinase	W8D0J5	Erwinia_phage	7.2e-21	34.9
WP_088024755.1\|1039436_1040393_+	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_004146965.1\|1040389_1040743_+	pilus assembly protein PilZ	NA	NA	NA	NA
WP_088024757.1\|1041036_1041255_+	hypothetical protein	NA	NA	NA	NA
WP_088024759.1\|1041518_1043990_+	AAA family ATPase	NA	NA	NA	NA
WP_088024761.1\|1044212_1044461_-	hypothetical protein	NA	NA	NA	NA
WP_088024763.1\|1044512_1044920_-	hypothetical protein	NA	NA	NA	NA
WP_065722614.1\|1045438_1045819_+	tautomerase family protein	NA	NA	NA	NA
WP_088024764.1\|1045866_1046289_+	hypothetical protein	NA	NA	NA	NA
WP_088024766.1\|1046356_1047430_-\|tail	phage tail protein	D5LGY1	Escherichia_phage	1.1e-92	50.4
WP_088024768.1\|1047420_1047636_-\|tail	phage tail protein	R9TR63	Vibrio_phage	7.0e-10	48.6
WP_088024770.1\|1047619_1048087_-\|tail	phage tail protein	A4PE53	Ralstonia_virus	2.6e-09	30.4
WP_088024773.1\|1048089_1050561_-\|tail	phage tail tape measure protein	A0A1W6JT50	Escherichia_phage	1.3e-19	23.5
WP_088024775.1\|1050681_1050972_-\|tail	phage tail assembly protein	A0A193GYZ8	Enterobacter_phage	2.5e-18	57.3
WP_088024779.1\|1051052_1051556_-\|tail	phage major tail tube protein	A0A193GYM4	Enterobacter_phage	1.4e-40	51.2
WP_088024781.1\|1051558_1052758_-\|tail	phage tail protein	D5LGY7	Escherichia_phage	4.8e-124	53.2
WP_088024784.1\|1052865_1053450_-	hypothetical protein	NA	NA	NA	NA
WP_088024786.1\|1053454_1054954_-	hypothetical protein	V9IQX0	Stenotrophomonas_phage	2.6e-71	57.3
WP_088024787.1\|1054961_1055741_-\|tail	phage tail protein I	V9IQK7	Stenotrophomonas_phage	1.9e-44	50.0
WP_088024789.1\|1055733_1056630_-\|plate	baseplate assembly protein	V5YTH6	Pseudomonas_phage	2.4e-80	55.8
WP_049444104.1\|1056632_1056971_-\|plate	phage baseplate protein	A0A193GYY8	Enterobacter_phage	1.0e-31	61.3
WP_088024790.1\|1057023_1057614_-\|plate	phage baseplate assembly protein V	A0A193GYL5	Enterobacter_phage	4.3e-25	38.7
WP_088024792.1\|1057610_1058165_-	hypothetical protein	NA	NA	NA	NA
WP_156476665.1\|1058281_1058629_-	hypothetical protein	NA	NA	NA	NA
WP_157664568.1\|1058627_1058828_+	hypothetical protein	NA	NA	NA	NA
WP_088024795.1\|1058908_1059394_-	glycoside hydrolase family 104 protein	D5LH07	Escherichia_phage	2.7e-41	55.0
WP_057501923.1\|1059390_1059741_-	hypothetical protein	NA	NA	NA	NA
WP_061479755.1\|1059737_1060187_-	hypothetical protein	NA	NA	NA	NA
WP_061479756.1\|1060522_1060906_-	hypothetical protein	NA	NA	NA	NA
WP_088024797.1\|1061060_1061699_-	hypothetical protein	A0A1V0DYI4	Shewanella_phage	4.5e-20	41.8
WP_088024799.1\|1061739_1061967_-	hypothetical protein	NA	NA	NA	NA
WP_088024800.1\|1062124_1064461_-	toprim domain-containing protein	A0A088FVF8	Escherichia_phage	1.1e-135	43.4

DBSCAN-SWA_3

2833935 : 2869723

uncultured_Caudovirales_phage(19.05%)

terminase,protease,integrase,head,capsid,portal,tail

attL 2824050:2824067|attR 2847619:2847636

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2824050:2824067	attL	NA	NA	NA	NA
WP_088026397.1\|2833935_2835120_+\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	5.6e-101	50.6
WP_088026398.1\|2835193_2836393_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_088026399.1\|2836392_2837004_+	DUF4411 family protein	NA	NA	NA	NA
WP_088028399.1\|2837051_2837405_-	hypothetical protein	B7SYF7	Stenotrophomonas_phage	4.2e-44	84.1
WP_088026401.1\|2838062_2838491_-	BLUF domain-containing protein	NA	NA	NA	NA
WP_088026402.1\|2838667_2839282_-	hypothetical protein	NA	NA	NA	NA
WP_088026403.1\|2839343_2839616_+	hypothetical protein	NA	NA	NA	NA
WP_088026405.1\|2840673_2840880_-	hypothetical protein	NA	NA	NA	NA
WP_157664590.1\|2840956_2848417_-\|tail	phage tail protein	I7HDJ4	Xanthomonas_virus	0.0e+00	47.3
2847619:2847636	attR	NA	NA	NA	NA
WP_088026406.1\|2848407_2848803_-	hypothetical protein	Q52PK9	Xanthomonas_phage	4.9e-25	47.2
WP_088026407.1\|2848802_2849264_-	DUF1833 domain-containing protein	I7GYA2	Xanthomonas_virus	9.4e-36	52.0
WP_088026408.1\|2849260_2849617_-	hypothetical protein	C4ML17	Xanthomonas_virus	1.3e-21	42.4
WP_088026409.1\|2849680_2853028_-\|tail	phage tail tape measure protein	A0A2R3UAA7	Siphoviridae_environmental_samples	1.5e-29	35.6
WP_088028401.1\|2853536_2853755_-	hypothetical protein	NA	NA	NA	NA
WP_008265925.1\|2853859_2854207_-	hypothetical protein	G9FHI3	Rhodococcus_phage	3.4e-22	52.2
WP_088026411.1\|2854210_2854663_-\|tail	phage tail protein	NA	NA	NA	NA
WP_088026412.1\|2854730_2855069_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_088026413.1\|2855065_2855467_-	HK97 gp10 family phage protein	A0A1W6JP15	Morganella_phage	3.6e-07	32.2
WP_088026414.1\|2855459_2855807_-	hypothetical protein	NA	NA	NA	NA
WP_088026415.1\|2855806_2856115_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4J8C5	uncultured_Caudovirales_phage	7.1e-24	51.0
WP_088026416.1\|2856670_2857882_-\|capsid	phage major capsid protein	A0A2H4J8D1	uncultured_Caudovirales_phage	9.7e-141	63.4
WP_088026417.1\|2857878_2858526_-\|head,protease	HK97 family phage prohead protease	A0A2H4JA51	uncultured_Caudovirales_phage	1.9e-79	72.8
WP_088026418.1\|2858518_2859778_-\|portal	phage portal protein	A0A2H4JFN7	uncultured_Caudovirales_phage	2.1e-162	71.4
WP_088028402.1\|2859774_2861541_-\|terminase	terminase	A0A0U2C138	Paracoccus_phage	1.1e-148	51.1
WP_088028404.1\|2861614_2861893_-	hypothetical protein	NA	NA	NA	NA
WP_088026419.1\|2862189_2862516_-	hypothetical protein	NA	NA	NA	NA
WP_088026420.1\|2862679_2863039_-	DUF1064 domain-containing protein	Q3HQZ9	Burkholderia_phage	1.4e-39	65.2
WP_088026421.1\|2863144_2863741_-	hypothetical protein	NA	NA	NA	NA
WP_088028406.1\|2863901_2864309_-	hypothetical protein	NA	NA	NA	NA
WP_088026422.1\|2864356_2864671_-	hypothetical protein	NA	NA	NA	NA
WP_088026423.1\|2864667_2865156_-	glycoside hydrolase family 104 protein	D5LH07	Escherichia_phage	8.9e-69	78.9
WP_088026424.1\|2865253_2865958_-	hypothetical protein	C8CLH7	Xylella_phage	1.1e-46	46.5
WP_088026425.1\|2866028_2866232_-	hypothetical protein	NA	NA	NA	NA
WP_088026426.1\|2866228_2866597_-	hypothetical protein	NA	NA	NA	NA
WP_088026427.1\|2866596_2866791_-	hypothetical protein	NA	NA	NA	NA
WP_088026428.1\|2866787_2867459_-	hypothetical protein	A0A1B0VMD9	Pseudomonas_phage	9.2e-24	36.3
WP_088026429.1\|2867448_2868342_-	helix-turn-helix domain-containing protein	A0A0U4IBP5	Pseudomonas_phage	5.5e-32	40.8
WP_088026430.1\|2868343_2868655_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_088026431.1\|2868651_2869182_-	hypothetical protein	B7SYH6	Stenotrophomonas_phage	9.4e-40	48.0
WP_088028408.1\|2869291_2869723_-	hypothetical protein	W6MWX8	Pseudomonas_phage	9.4e-06	50.0

Anti-CRISPR protein detection

Acr_ID: NZ_CP015612.1|WP_005408313.1|1034394_1034634_+|acyl-carrier-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP015612.1|WP_005408313.1|1034394_1034634_+|acyl-carrier-protein

1034394_1034634_+

79 aa aa

974741-1064461

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP015612_7	Orphan	7.1\|3822727\|29\|NZ_CP015612\|CRISPRCasFinder	3822727-3822755	29	1037590-1037562	1

1. spacer 7.1|3822727|29|NZ_CP015612|CRISPRCasFinder matches to NZ_CP015612 position: 1037590-1037562, mismatch: 1

cagtagatccacgccatgcgtggatgcac	CRISPR spacer
cagtagatccacgccatgcgtggatgaac	Protospacer
************************** **

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015612

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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