CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP022229	Escherichia coli strain WCHEC96200 chromosome, complete genome	3 crisprs	cas3,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,WYL,PD-DExK,RT,DEDDh,c2c9_V-U4,DinG	11	8
NZ_CP022228	Escherichia coli strain WCHEC96200 plasmid p1_000200, complete sequence	0 crisprs	c2c9_V-U4	0	1
NZ_CP022227	Escherichia coli strain WCHEC96200 plasmid pCTXM15_000200, complete sequence	0 crisprs	csa3,RT	0	1
NZ_CP022226	Escherichia coli strain WCHEC96200 plasmid pNDM4_WCHEC96200, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022229_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022229_1

893749-894384

TypeI-E

I-E

Consensus_repeat	Method
TTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGATTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR
TTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder

10 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP022229_1

>merge|NZ_CP022229|1|893749-894384|CRT,PILER-CR,CRISPRCasFinder
AGTTCTACCGCAGGGGCGGGGAACTCCAAGTGATGTCCATCATCGCATCCAGTGCGTCCGGTTTATCCCCGCTGACGCGGGGAACACGTCAATAGGCGGCGTCCCGTAGCCGTCCCCTTCGGTTTATCCCCGCTGGCGCGGGGAACACGTTGAGGTCGATAAGTACGAACGGTTTCCCTGCGGTTTATCCCCGCTGGCGCGGGGAACACGATCGCCTGCTCCAGCGTCACTCCCTGCCCCTCGATTTATCCCCGCTGGCGCGGGGAACACTTCTGATACGTACTGAGGCCGGTTGTGATACGCGATTTATCCCCGCTGGCGCGGGGAACACTAACCCCCAATGAAGTTAATAAAGTCTATGGCCGATTTATCCCCGCTGGCGCGGGGAACACATGAGATTAAAATACTCAGTACTCTTACTCGCCGATTTATCCCCGCTGGCGCGGGGAACACCAGCGTGGCGCGATAAAGCAATGTGTCTGGCTCGATTTATCCCCGCTGGCGCGGGGAACACCAGAGGCAACCGACGCGGATTCAGTAGGAAAGCGATTTATCCCCGCTGGCGCGGGGAACACCGATAGACACTTTGCGGTCATTGTCTATTCGGCGATTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP022229|1|1|893749-894384|CRT
AGTTCTACCGCAGGGGCGGGGAACTC	CAAGTGATGTCCATCATCGCATCCAGTGCGTCCGG
TTTATCCCCGCTGACGCGGGGAACAC	GTCAATAGGCGGCGTCCCGTAGCCGTCCCCTTCGG
TTTATCCCCGCTGGCGCGGGGAACAC	GTTGAGGTCGATAAGTACGAACGGTTTCCCTGCGG
TTTATCCCCGCTGGCGCGGGGAACAC	GATCGCCTGCTCCAGCGTCACTCCCTGCCCCTCGA
TTTATCCCCGCTGGCGCGGGGAACAC	TTCTGATACGTACTGAGGCCGGTTGTGATACGCGA
TTTATCCCCGCTGGCGCGGGGAACAC	TAACCCCCAATGAAGTTAATAAAGTCTATGGCCGA
TTTATCCCCGCTGGCGCGGGGAACAC	ATGAGATTAAAATACTCAGTACTCTTACTCGCCGA
TTTATCCCCGCTGGCGCGGGGAACAC	CAGCGTGGCGCGATAAAGCAATGTGTCTGGCTCGA
TTTATCCCCGCTGGCGCGGGGAACAC	CAGAGGCAACCGACGCGGATTCAGTAGGAAAGCGA
TTTATCCCCGCTGGCGCGGGGAACAC	CGATAGACACTTTGCGGTCATTGTCTATTCGGCGA
TTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP022229|1|1|893807-894384|PILER-CR
CGGTTTATCCCCGCTGACGCGGGGAACAC	GTCAATAGGCGGCGTCCCGTAGCCGTCCCCTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTGAGGTCGATAAGTACGAACGGTTTCCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATCGCCTGCTCCAGCGTCACTCCCTGCCCCT
CGATTTATCCCCGCTGGCGCGGGGAACAC	TTCTGATACGTACTGAGGCCGGTTGTGATACG
CGATTTATCCCCGCTGGCGCGGGGAACAC	TAACCCCCAATGAAGTTAATAAAGTCTATGGC
CGATTTATCCCCGCTGGCGCGGGGAACAC	ATGAGATTAAAATACTCAGTACTCTTACTCGC
CGATTTATCCCCGCTGGCGCGGGGAACAC	CAGCGTGGCGCGATAAAGCAATGTGTCTGGCT
CGATTTATCCCCGCTGGCGCGGGGAACAC	CAGAGGCAACCGACGCGGATTCAGTAGGAAAG
CGATTTATCCCCGCTGGCGCGGGGAACAC	CGATAGACACTTTGCGGTCATTGTCTATTCGG
CGATTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP022229|1|1|893810-894384|CRISPRCasFinder
TTTATCCCCGCTGACGCGGGGAACAC	GTCAATAGGCGGCGTCCCGTAGCCGTCCCCTTCGG
TTTATCCCCGCTGGCGCGGGGAACAC	GTTGAGGTCGATAAGTACGAACGGTTTCCCTGCGG
TTTATCCCCGCTGGCGCGGGGAACAC	GATCGCCTGCTCCAGCGTCACTCCCTGCCCCTCGA
TTTATCCCCGCTGGCGCGGGGAACAC	TTCTGATACGTACTGAGGCCGGTTGTGATACGCGA
TTTATCCCCGCTGGCGCGGGGAACAC	TAACCCCCAATGAAGTTAATAAAGTCTATGGCCGA
TTTATCCCCGCTGGCGCGGGGAACAC	ATGAGATTAAAATACTCAGTACTCTTACTCGCCGA
TTTATCCCCGCTGGCGCGGGGAACAC	CAGCGTGGCGCGATAAAGCAATGTGTCTGGCTCGA
TTTATCCCCGCTGGCGCGGGGAACAC	CAGAGGCAACCGACGCGGATTCAGTAGGAAAGCGA
TTTATCCCCGCTGGCGCGGGGAACAC	CGATAGACACTTTGCGGTCATTGTCTATTCGGCGA
TTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022229.3\|WP_001295182.1\|885619_886381_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP022229.3\|WP_001246104.1\|889120_889444_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP022229.3\|WP_000956458.1\|903236_903389_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP022229.3\|WP_001521158.1\|900342_903042_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP022229.3\|WP_000568924.1\|886361_887411_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP022229.3\|WP_000144858.1\|894770_895694_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP022229.3\|WP_001521155.1\|895690_896341_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP022229.3\|WP_001521153.1\|892687_893725_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP022229.3\|WP_001173673.1\|889493_890099_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP022229.3\|WP_001521160.1\|903653_904388_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP022229.3\|WP_000372392.1\|891527_892436_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP022229.3\|WP_000029331.1\|898149_898686_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP022229.3\|WP_001521157.1\|897079_898135_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP022229.3\|WP_020234039.1\|896322_897069_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP022229.3\|WP_001090361.1\|890098_891526_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP022229.3\|WP_001521152.1\|887407_887887_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP022229.3\|WP_000246138.1\|887886_888597_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP022229.3\|WP_001084115.1\|898682_900245_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP022229.3\|WP_000517476.1\|888615_888927_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP022229.3\|WP_001521154.1\|894480_894774_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930

Protein	Function_ID	Function_description	E-value
NZ_CP022229.3\|WP_001295182.1\|885619_886381_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP022229.3\|WP_001246104.1\|889120_889444_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP022229.3\|WP_000956458.1\|903236_903389_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP022229.3\|WP_001521158.1\|900342_903042_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP022229.3\|WP_000568924.1\|886361_887411_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP022229.3\|WP_000144858.1\|894770_895694_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.11358e-157
NZ_CP022229.3\|WP_001521155.1\|895690_896341_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	3.05036e-90
NZ_CP022229.3\|WP_001521153.1\|892687_893725_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP022229.3\|WP_001173673.1\|889493_890099_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP022229.3\|WP_001521160.1\|903653_904388_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	4.91666e-137
NZ_CP022229.3\|WP_000372392.1\|891527_892436_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP022229.3\|WP_000029331.1\|898149_898686_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	4.72866e-28
NZ_CP022229.3\|WP_001521157.1\|897079_898135_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	7.45078e-156
NZ_CP022229.3\|WP_020234039.1\|896322_897069_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.25317e-47
NZ_CP022229.3\|WP_001090361.1\|890098_891526_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP022229.3\|WP_001521152.1\|887407_887887_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	2.39634e-105
NZ_CP022229.3\|WP_000246138.1\|887886_888597_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP022229.3\|WP_001084115.1\|898682_900245_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP022229.3\|WP_000517476.1\|888615_888927_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP022229.3\|WP_001521154.1\|894480_894774_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	9.65861e-64

>NZ_CP022229.3|WP_001521153.1|892687_893725_+|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSAKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP022229.3|WP_000372392.1|891527_892436_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP022229.3|WP_001090361.1|890098_891526_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP022229.3|WP_001173673.1|889493_890099_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP022229.3|WP_001246104.1|889120_889444_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP022229.3|WP_000517476.1|888615_888927_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP022229.3|WP_000246138.1|887886_888597_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP022229.3|WP_001521152.1|887407_887887_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPLIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP022229.3|WP_000568924.1|886361_887411_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP022229.3|WP_001295182.1|885619_886381_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>NZ_CP022229.3|WP_001521154.1|894480_894774_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRIAIWLLEVRAGVYVGDTSKRIREMIWQQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGVRLVSFLPVDNQ
>NZ_CP022229.3|WP_000144858.1|894770_895694_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP022229.3|WP_001521155.1|895690_896341_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLLPAQLLHLVGRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDIFTIECRPFAPELRTGQSLCFNLRANPTICKAGKRHDLLMEAKRQVRGQVEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP022229.3|WP_020234039.1|896322_897069_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSAPDLLSAIISRRDYYTDAWWMVAVATTPDASYRLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYQQYQDSFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>NZ_CP022229.3|WP_001521157.1|897079_898135_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECVSFDVMNKQGSMKDVLDFICA
>NZ_CP022229.3|WP_000029331.1|898149_898686_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSEGRFTRLSAVKTPDDLLRQLRRAVKLLNGSVNLISLAEDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>NZ_CP022229.3|WP_001084115.1|898682_900245_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRYKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKDHRRWDDIWEDGLESEKLREALLSLEHAFQFGPDSPSFMQDFEALTGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEYLCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQNDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLDKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRHIEEGQDADELLSKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQNAKAAREKKQEAAE
>NZ_CP022229.3|WP_001521158.1|900342_903042_-|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKSNCFGLTDYFRQLGFADTEQAAQFFAWLLCWHDTGKFARSFQQLYLHPQLKVPEGARKNYEKISHSTLGYWLWHHYLSEYEELLPSSSLSPRKLKRVMEMWMPITTGHHGRPPDRIDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLVQAQNALTVFPLKAKVAPFTGINTLFPFIENPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQCDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVHSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKEDSSQRAGKVLICTQVLESSVDCDMDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIASVVKPYANGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRKDPEMANVILVTDDESCGYSAMEGLTGKVG
>NZ_CP022229.3|WP_000956458.1|903236_903389_-|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP022229.3|WP_001521160.1|903653_904388_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRTNLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: NZ_CP022229_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022229_2

921522-921855

Orphan

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	PILER-CR

5 spacers

The CRISPR arrays of NZ_CP022229_2

>merge|NZ_CP022229|2|921522-921855|CRISPRCasFinder,CRT,PILER-CR
TGGTTTATTCCCGCTGGTGCGGGGAACTCATCAGTGATATCCAACATTGCGGAGCTAAACGCGGTTTATCCCCGCTGGCGCGGGGAACTCTAATATCCCTGGCGATAATCAACCGGCTTACTCGGTTTATCCCCGCTGGCGCGGGGAACTCGAGAGCGAGGGGAGATTCCGGCAGGGCGTGCACGGTTTATCCCCGCTGGCGCGGGGAACTCGCGGGTATGCTCCGCTCCGTGTTCGACAAACTCGGTTTATCCCCGCTGGCGCGGGGAACTCAAGGTCGCGGGGACGCCACGGGCAGTCAATGTCGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP022229|2|2|921522-921855|CRISPRCasFinder
TGGTTTATTCCCGCTGGTGCGGGGAACTC	ATCAGTGATATCCAACATTGCGGAGCTAAACG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TAATATCCCTGGCGATAATCAACCGGCTTACT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GAGAGCGAGGGGAGATTCCGGCAGGGCGTGCA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCGGGTATGCTCCGCTCCGTGTTCGACAAACT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AAGGTCGCGGGGACGCCACGGGCAGTCAATGT
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP022229|2|2|921522-921855|CRT
TGGTTTATTCCCGCTGGTGCGGGGAACTC	ATCAGTGATATCCAACATTGCGGAGCTAAACG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TAATATCCCTGGCGATAATCAACCGGCTTACT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GAGAGCGAGGGGAGATTCCGGCAGGGCGTGCA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCGGGTATGCTCCGCTCCGTGTTCGACAAACT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AAGGTCGCGGGGACGCCACGGGCAGTCAATGT
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP022229|2|2|921583-921855|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TAATATCCCTGGCGATAATCAACCGGCTTACT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GAGAGCGAGGGGAGATTCCGGCAGGGCGTGCA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCGGGTATGCTCCGCTCCGTGTTCGACAAACT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AAGGTCGCGGGGACGCCACGGGCAGTCAATGT
CGGTTTATCCCCGCTGGCGCGGGGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022229.3\|WP_001199973.1\|922193_922865_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP022229.3\|WP_000254738.1\|928203_928539_-\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP022229.3\|WP_000036723.1\|924090_925389_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP022229.3\|WP_001521167.1\|913285_914065_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP022229.3\|WP_001130266.1\|910270_910846_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP022229.3\|WP_000109536.1\|909993_910254_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP022229.3\|WP_000059301.1\|915473_916928_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP022229.3\|WP_000186450.1\|932504_935261_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NZ_CP022229.3\|WP_021523232.1\|916997_917783_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP022229.3\|WP_100190663.1\|910980_912329_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP022229.3\|WP_020232912.1\|923158_924031_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP022229.3\|WP_000581937.1\|928538_928787_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP022229.3\|WP_000039721.1\|919405_920884_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP022229.3\|WP_001098106.1\|914042_915380_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP022229.3\|WP_001521172.1\|931146_932448_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP022229.3\|WP_000210878.1\|925475_927113_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP022229.3\|WP_020233775.1\|918101_919379_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP022229.3\|WP_000226798.1\|928864_931099_-\|GTP-diphosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP022229.3\|WP_001071643.1\|927340_928132_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP022229.3\|WP_001521165.1\|912428_913289_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936

Protein	Function_ID	Function_description	E-value
NZ_CP022229.3\|WP_001199973.1\|922193_922865_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP022229.3\|WP_000254738.1\|928203_928539_-\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP022229.3\|WP_000036723.1\|924090_925389_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP022229.3\|WP_001521167.1\|913285_914065_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	8.81851e-61
NZ_CP022229.3\|WP_001130266.1\|910270_910846_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP022229.3\|WP_000109536.1\|909993_910254_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	4.39108e-42
NZ_CP022229.3\|WP_000059301.1\|915473_916928_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.6361e-82
NZ_CP022229.3\|WP_000186450.1\|932504_935261_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NZ_CP022229.3\|WP_021523232.1\|916997_917783_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.07958e-139
NZ_CP022229.3\|WP_100190663.1\|910980_912329_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.29095e-52
NZ_CP022229.3\|WP_020232912.1\|923158_924031_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	6.02863e-94
NZ_CP022229.3\|WP_000581937.1\|928538_928787_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP022229.3\|WP_000039721.1\|919405_920884_+\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	2.76431e-108
NZ_CP022229.3\|WP_001098106.1\|914042_915380_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.1165e-50
NZ_CP022229.3\|WP_001521172.1\|931146_932448_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP022229.3\|WP_000210878.1\|925475_927113_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP022229.3\|WP_020233775.1\|918101_919379_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.01506e-28
NZ_CP022229.3\|WP_000226798.1\|928864_931099_-\|GTP-diphosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP022229.3\|WP_001071643.1\|927340_928132_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	9.36315e-160
NZ_CP022229.3\|WP_001521165.1\|912428_913289_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	8.34461e-89

>NZ_CP022229.3|WP_000039721.1|919405_920884_+|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKTWAWSEDAAVMEKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKLLPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFMPVESNAKRYNAMNKGIFKELTKHTDVILKKSYEVMHGELGNADSIQSWSNA
>NZ_CP022229.3|WP_020233775.1|918101_919379_+|MFS-transporter
MQHNSYRRWIALAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGYWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP022229.3|WP_021523232.1|916997_917783_-|SDR-family-oxidoreductase
MSIESLNALSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILINNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP022229.3|WP_000059301.1|915473_916928_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWTLLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP022229.3|WP_001098106.1|914042_915380_-|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP022229.3|WP_001521167.1|913285_914065_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGNSGPDVSLLRSLLGADEQAAAALLLAQRKNGTSMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQYQNPLELIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFITLEQRTENGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAVGKAAIIRKTVAAESPAMQCLQLARAEQQRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP022229.3|WP_001521165.1|912428_913289_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAATASWQAAQDFSGCTLAHWKIEPQPAVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGADKNATLPSGMQQLNIVPGALPDWLVSIENLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHAECQ
>NZ_CP022229.3|WP_100190663.1|910980_912329_+|IS3-family-transposase
MKHSFEVKLAAVNHYLAGHAGIISTAKLFQLSHTSLSHWINLFLLHGPRALDCRHKRSYSPEDKLCVVLYALGHSESLPRVAARFNIPSHNTVKNWIKGYRKSGNEAFIRRRKEKSMTRSDDTHENEANMTPEEMKNELRYLRAENAYLKAMQEHLLEKKPPGAGEKTKVIRSLRCGHCQSDLLKAAGLARSTLYYQLSLQKAKDKYADVKQLIASIFHEHRGCYGYRRIHCELQKRGLKFSGKTVRKLMQQLGLKSPVRLKKYRSYRGNMGLAAENILQRQFKAEAPCEKWVTDITEFRAGGQKLYLSPILDLFNGEIVAWETACRPTEELVKRMLNKGLESLAEGEKPLLHSDQGWHYRIKSYQSALADRGLVQSMSRKGNCLDNAVMENFFGHLKEEMYYRRDYRNVEELENAVNEYITYWNQKRIKLSLGGLSPVEYRTEHQKAG
>NZ_CP022229.3|WP_001130266.1|910270_910846_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP022229.3|WP_000109536.1|909993_910254_+|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTVQRLINACPAGLFSLTPEGDLRVDYRGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP022229.3|WP_001199973.1|922193_922865_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP022229.3|WP_020232912.1|923158_924031_+|YgcG-family-protein
MRYFILIFTFVCSFIAAQPTIVPSLQQQVTDLTSSLNSQEKKELTYKLESIFNNTQVQIAVLIVPTTKDETIEKYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAQGLELAINALNNQLTSQHQYPANPSEIESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDLFLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSDGGGSSGGGGASGRW
>NZ_CP022229.3|WP_000036723.1|924090_925389_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP022229.3|WP_000210878.1|925475_927113_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP022229.3|WP_001071643.1|927340_928132_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVIDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP022229.3|WP_000254738.1|928203_928539_-|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP022229.3|WP_000581937.1|928538_928787_-|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP022229.3|WP_000226798.1|928864_931099_-|GTP-diphosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRECVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVMANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP022229.3|WP_001521172.1|931146_932448_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDNPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLDSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVAGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLHNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP022229.3|WP_000186450.1|932504_935261_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG

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Crispr_ID: NZ_CP022229_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022229_3

2686879-2687028

Orphan

Consensus_repeat	Method
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022229_3

>merge|NZ_CP022229|3|2686879-2687028|CRISPRCasFinder
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCATGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTGCGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

>NZ_CP022229|3|3|2686879-2687028|CRISPRCasFinder
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	TGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTG
CGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022229.3\|WP_001128347.1\|2693830_2695150_-\|gnt-II-system-L-idonate-transporter	unknown	unknown	gnl\|CDD\|129873
NZ_CP022229.3\|WP_001295681.1\|2689942_2691025_+\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP022229.3\|WP_000998695.1\|2695212_2695977_-\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|181225
NZ_CP022229.3\|WP_000786399.1\|2686267_2686711_-\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP022229.3\|WP_087503492.1\|2682160_2683357_+\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP022229.3\|WP_000896738.1\|2697248_2697812_+\|gluconokinase	unknown	unknown	gnl\|CDD\|182097
NZ_CP022229.3\|WP_000256681.1\|2676872_2677466_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP022229.3\|WP_001318460.1\|2697815_2698835_-\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP022229.3\|WP_001197411.1\|2696000_2697032_-\|L-idonate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|182130
NZ_CP022229.3\|WP_000584114.1\|2688842_2689943_+\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP022229.3\|WP_000036448.1\|2678185_2679781_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022229.3\|WP_001309159.1\|2692765_2693764_-\|DNA-binding-transcriptional-regulator-IdnR	unknown	unknown	gnl\|CDD\|380489
NZ_CP022229.3\|WP_029701911.1\|2687064_2688576_-\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP022229.3\|WP_000500687.1\|2676088_2676802_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP022229.3\|WP_021523335.1\|2691185_2692688_-\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP022229.3\|WP_000416387.1\|2683412_2686268_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP022229.3\|WP_000012907.1\|2679836_2680841_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP022229.3\|WP_000002953.1\|2681002_2681419_+\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP022229.3\|WP_001059412.1\|2681464_2681968_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP022229.3\|WP_001326836.1\|2677610_2678063_+\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345

Protein	Function_ID	Function_description	E-value
NZ_CP022229.3\|WP_001318460.1\|2697815_2698835_-\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.21683e-169
NZ_CP022229.3\|WP_001295681.1\|2689942_2691025_+\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP022229.3\|WP_000998695.1\|2695212_2695977_-\|gluconate-5-dehydrogenase	gnl\|CDD\|181225	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional.	0
NZ_CP022229.3\|WP_000786399.1\|2686267_2686711_-\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NZ_CP022229.3\|WP_087503492.1\|2682160_2683357_+\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	1.30951e-150
NZ_CP022229.3\|WP_000896738.1\|2697248_2697812_+\|gluconokinase	gnl\|CDD\|182097	PRK09825, idnK, gluconokinase.	1.3617e-126
NZ_CP022229.3\|WP_000256681.1\|2676872_2677466_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.07846e-09
NZ_CP022229.3\|WP_001197411.1\|2696000_2697032_-\|L-idonate-5-dehydrogenase	gnl\|CDD\|182130	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional.	0
NZ_CP022229.3\|WP_029701911.1\|2687064_2688576_-\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP022229.3\|WP_001128347.1\|2693830_2695150_-\|gnt-II-system-L-idonate-transporter	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP022229.3\|WP_001309159.1\|2692765_2693764_-\|DNA-binding-transcriptional-regulator-IdnR	gnl\|CDD\|380489	cd01575, PBP1_GntR, ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. This group represents the ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of GntR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding, which in turn changes the DNA binding affinity of the repressor.	1.4437e-109
NZ_CP022229.3\|WP_000584114.1\|2688842_2689943_+\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP022229.3\|WP_000500687.1\|2676088_2676802_-\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	5.2218e-149
NZ_CP022229.3\|WP_021523335.1\|2691185_2692688_-\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP022229.3\|WP_000416387.1\|2683412_2686268_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP022229.3\|WP_000012907.1\|2679836_2680841_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP022229.3\|WP_000002953.1\|2681002_2681419_+\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
NZ_CP022229.3\|WP_001059412.1\|2681464_2681968_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.73712e-19
NZ_CP022229.3\|WP_001326836.1\|2677610_2678063_+\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.64234e-69

>NZ_CP022229.3|WP_000786399.1|2686267_2686711_-|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP022229.3|WP_000416387.1|2683412_2686268_-|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADNKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP022229.3|WP_087503492.1|2682160_2683357_+|DUF898-domain-containing-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFFYFAILMTVSADMPLVGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSLKRFWWVTFFLPILMAIGMGAVFFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQISNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLARISRGIMPSLPFL
>NZ_CP022229.3|WP_001059412.1|2681464_2681968_-|GNAT-family-N-acetyltransferase
MNNIAPQSPVMRRLTQQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEFDGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLREL
>NZ_CP022229.3|WP_000002953.1|2681002_2681419_+|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP022229.3|WP_000012907.1|2679836_2680841_-|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
>NZ_CP022229.3|WP_000036448.1|2678185_2679781_+|hypothetical-protein
MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNNFARNAEGQDNTRNILDPKTFLEFLVKIFTLGYVDFSNRSNEAGRNMMAHIESSSYIKNNDGSEIMKFVMNNPEGERADLSKVEIEITLSTITTMGTRQGHTAIIFQQPDGSTNRYEGKSFERKDESSLHLITNKVLACYQREANKEVALLLNNHQLNWKDAIDYNELLEKPLASTLEKIKKEHLLLMPHVCDDTIPYLLGEGGILEEINGLKTLHDTKIDSGTEGNDEINNIKINLSNILIDSLDDAKINLEKVIDSMLETFFKLPYINDVKILEWCFNQSMQYSDDTTKIKHARSVIDHIDFNCDQSKIAETLFFNLNKEPYKNSPELQELIWEKLVVYVNDFNLSNQEKSRLILRLFDDVKLVFDKVPLSILVNDIFLKDFFMKQPDFAKWYFYQLLKSYEGEQMYLNELGYVYGDEEKTKEIVNKLPGYVVKIFEEKIDNELKIRTRMMEILRDEQINIYEYINEKQLEKLNPQGNLRIAIEKFGWNNKPITA
>NZ_CP022229.3|WP_001326836.1|2677610_2678063_+|YhcH/YjgK/YiaL-family-protein
MIIGNIHNLQPWLPQELRQAIEHIKAHVTPETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLRGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP022229.3|WP_000256681.1|2676872_2677466_+|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKVGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFMSTVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE
>NZ_CP022229.3|WP_000500687.1|2676088_2676802_-|SDR-family-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAEHLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
>NZ_CP022229.3|WP_029701911.1|2687064_2688576_-|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMCMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP022229.3|WP_000584114.1|2688842_2689943_+|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP022229.3|WP_001295681.1|2689942_2691025_+|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP022229.3|WP_021523335.1|2691185_2692688_-|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGVAQAGTVSEKLLARLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDETHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP022229.3|WP_001309159.1|2692765_2693764_-|DNA-binding-transcriptional-regulator-IdnR
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL
>NZ_CP022229.3|WP_001128347.1|2693830_2695150_-|gnt-II-system-L-idonate-transporter
MPLIIIAAGVALLLILMIVFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
>NZ_CP022229.3|WP_000998695.1|2695212_2695977_-|gluconate-5-dehydrogenase
MNDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV
>NZ_CP022229.3|WP_001197411.1|2696000_2697032_-|L-idonate-5-dehydrogenase
MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF
>NZ_CP022229.3|WP_000896738.1|2697248_2697812_+|gluconokinase
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGSASDQRCE
>NZ_CP022229.3|WP_001318460.1|2697815_2698835_-|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022229_1	1.1\|893775\|35\|NZ_CP022229\|CRT	893775-893809	35	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246934-246968	0	1.0
NZ_CP022229_1	1.16\|894141\|32\|NZ_CP022229\|PILER-CR	894141-894172	32	NZ_CP037443	Klebsiella sp. PO552 plasmid p2, complete sequence	42679-42710	1	0.969
NZ_CP022229_1	1.7\|894141\|35\|NZ_CP022229\|CRT,CRISPRCasFinder	894141-894175	35	NZ_CP037443	Klebsiella sp. PO552 plasmid p2, complete sequence	42676-42710	2	0.943
NZ_CP022229_2	2.3\|921673\|32\|NZ_CP022229\|CRISPRCasFinder,CRT,PILER-CR	921673-921704	32	NC_016040	Sulfobacillus thermotolerans strain Y0017 plasmid pY0017, complete sequence	37866-37897	6	0.812
NZ_CP022229_1	1.13\|893958\|32\|NZ_CP022229\|PILER-CR	893958-893989	32	MT110073	Stenotrophomonas phage vB_SmaS_DLP_3, complete genome	39410-39441	7	0.781
NZ_CP022229_1	1.12\|893897\|32\|NZ_CP022229\|PILER-CR	893897-893928	32	NZ_CP044084	Pseudomonas luteola strain FDAARGOS_637 plasmid unnamed1, complete sequence	347859-347890	8	0.75
NZ_CP022229_1	1.15\|894080\|32\|NZ_CP022229\|PILER-CR	894080-894111	32	KC847113	Bacillus phage PBP180, complete sequence	100-131	8	0.75
NZ_CP022229_2	2.2\|921612\|32\|NZ_CP022229\|CRISPRCasFinder,CRT,PILER-CR	921612-921643	32	MN855878	Bacteriophage sp. isolate 336, complete genome	5171-5202	8	0.75
NZ_CP022229_2	2.5\|921795\|32\|NZ_CP022229\|CRISPRCasFinder,CRT,PILER-CR	921795-921826	32	NZ_CP045381	Labrenzia sp. THAF35 plasmid pTHAF35_a, complete sequence	107507-107538	8	0.75
NZ_CP022229_2	2.5\|921795\|32\|NZ_CP022229\|CRISPRCasFinder,CRT,PILER-CR	921795-921826	32	NZ_CP019631	Labrenzia aggregata strain RMAR6-6 plasmid unnamed1, complete sequence	199281-199312	8	0.75
NZ_CP022229_1	1.11\|893836\|32\|NZ_CP022229\|PILER-CR	893836-893867	32	NZ_CP016293	Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence	11267-11298	9	0.719
NZ_CP022229_1	1.15\|894080\|32\|NZ_CP022229\|PILER-CR	894080-894111	32	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	20152-20183	9	0.719
NZ_CP022229_1	1.15\|894080\|32\|NZ_CP022229\|PILER-CR	894080-894111	32	NC_049837	Klebsiella phage vB_KpnS_Alina, complete genome	13583-13614	9	0.719
NZ_CP022229_1	1.16\|894141\|32\|NZ_CP022229\|PILER-CR	894141-894172	32	NZ_CP019063	Rahnella sp. ERMR1:05 plasmid unnamed1, complete sequence	287201-287232	9	0.719
NZ_CP022229_1	1.15\|894080\|32\|NZ_CP022229\|PILER-CR	894080-894111	32	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	179050-179081	10	0.688
NZ_CP022229_1	1.6\|894080\|35\|NZ_CP022229\|CRT,CRISPRCasFinder	894080-894114	35	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	20152-20186	12	0.657

1. spacer 1.1|893775|35|NZ_CP022229|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 0, identity: 1.0

caagtgatgtccatcatcgcatccagtgcgtccgg	CRISPR spacer
caagtgatgtccatcatcgcatccagtgcgtccgg	Protospacer
***********************************

2. spacer 1.16|894141|32|NZ_CP022229|PILER-CR matches to NZ_CP037443 (Klebsiella sp. PO552 plasmid p2, complete sequence) position: , mismatch: 1, identity: 0.969

atgagattaaaatactcagtactcttactcgc	CRISPR spacer
atgagattaaaatactcagcactcttactcgc	Protospacer
*******************.************

3. spacer 1.7|894141|35|NZ_CP022229|CRT,CRISPRCasFinder matches to NZ_CP037443 (Klebsiella sp. PO552 plasmid p2, complete sequence) position: , mismatch: 2, identity: 0.943

atgagattaaaatactcagtactcttactcgccga	CRISPR spacer
atgagattaaaatactcagcactcttactcgccgt	Protospacer
*******************.**************

4. spacer 2.3|921673|32|NZ_CP022229|CRISPRCasFinder,CRT,PILER-CR matches to NC_016040 (Sulfobacillus thermotolerans strain Y0017 plasmid pY0017, complete sequence) position: , mismatch: 6, identity: 0.812

gagagcgaggggagattccggcagggcgtgca	CRISPR spacer
aatcgtgaggggatcttccggcagggcgtgca	Protospacer
.*  *.*******  *****************

5. spacer 1.13|893958|32|NZ_CP022229|PILER-CR matches to MT110073 (Stenotrophomonas phage vB_SmaS_DLP_3, complete genome) position: , mismatch: 7, identity: 0.781

gatcgcctgctccagcgtcactccctgcccct	CRISPR spacer
gttcgcctgctccagcgtcaatgccccctccc	Protospacer
* ****************** * **. *.**.

6. spacer 1.12|893897|32|NZ_CP022229|PILER-CR matches to NZ_CP044084 (Pseudomonas luteola strain FDAARGOS_637 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gttgaggtcgataagtacgaacggtttccctg	CRISPR spacer
gaagaggtcgatgagtacgaatggttacagcg	Protospacer
*  *********.********.**** *  .*

7. spacer 1.15|894080|32|NZ_CP022229|PILER-CR matches to KC847113 (Bacillus phage PBP180, complete sequence) position: , mismatch: 8, identity: 0.75

taacccccaatgaagttaataaagtctatggc	CRISPR spacer
ttctctctaatgtagttaataaagtcgatggt	Protospacer
*  .*.*.**** ************* ****.

8. spacer 2.2|921612|32|NZ_CP022229|CRISPRCasFinder,CRT,PILER-CR matches to MN855878 (Bacteriophage sp. isolate 336, complete genome) position: , mismatch: 8, identity: 0.75

taatatccc----tggcgataatcaaccggcttact	CRISPR spacer
----acgccatggtggcgataatcatcctgcttact	Protospacer
    *. **    ************ ** *******

9. spacer 2.5|921795|32|NZ_CP022229|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045381 (Labrenzia sp. THAF35 plasmid pTHAF35_a, complete sequence) position: , mismatch: 8, identity: 0.75

aaggtcgcggggacgccacgggcagtcaatgt	CRISPR spacer
gatttcgctgggaccccacgggcagtcgacgg	Protospacer
.*  **** ***** ************.*.*

10. spacer 2.5|921795|32|NZ_CP022229|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019631 (Labrenzia aggregata strain RMAR6-6 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aaggtcgcggggacgccacgggcagtcaatgt	CRISPR spacer
gatttcgctgggaccccacgggcagtcgacgg	Protospacer
.*  **** ***** ************.*.*

11. spacer 1.11|893836|32|NZ_CP022229|PILER-CR matches to NZ_CP016293 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

gtcaataggcggcgtcccgtagccgtcccctt	CRISPR spacer
gtgctctggcggcgtgccgtagccatccccga	Protospacer
**   . ******** ********.*****

12. spacer 1.15|894080|32|NZ_CP022229|PILER-CR matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

taacccccaatgaagttaataaagtctatggc	CRISPR spacer
ctttaggcaatgaagttaaaaaattctatggc	Protospacer
.  .   ************ *** ********

13. spacer 1.15|894080|32|NZ_CP022229|PILER-CR matches to NC_049837 (Klebsiella phage vB_KpnS_Alina, complete genome) position: , mismatch: 9, identity: 0.719

taacccccaatgaagttaataaagtctatggc	CRISPR spacer
acattggcgatgaagttaataacgtgtatggc	Protospacer
  *..  *.************* ** ******

14. spacer 1.16|894141|32|NZ_CP022229|PILER-CR matches to NZ_CP019063 (Rahnella sp. ERMR1:05 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

atgagattaaaatactcagtactcttactcgc	CRISPR spacer
cgggaattaacatactcggtactcttaccgtc	Protospacer
  *..***** ******.**********.  *

15. spacer 1.15|894080|32|NZ_CP022229|PILER-CR matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 10, identity: 0.688

taacccccaatgaagttaataaagtctatggc	CRISPR spacer
gtagattcaatgaagttaataaaaactatgat	Protospacer
  *  ..****************. *****..

16. spacer 1.6|894080|35|NZ_CP022229|CRT,CRISPRCasFinder matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 12, identity: 0.657

taacccccaatgaagttaataaagtctatggccga	CRISPR spacer
ctttaggcaatgaagttaaaaaattctatggcgat	Protospacer
.  .   ************ *** ******** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

68098 : 75616

Escherichia_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021523155.1\|68098_68647_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	4.4e-48	54.4
WP_021523156.1\|68651_69530_-	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	1.9e-106	64.5
WP_021523157.1\|69587_70487_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.7e-28	35.1
WP_001515524.1\|70486_71572_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.3e-101	54.2
WP_021523158.1\|71943_72837_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_021523159.1\|73068_74064_-	SDR family oxidoreductase	A0A1V0QG29	Shearwaterpox_virus	2.5e-09	26.0
WP_087503483.1\|74221_75616_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	7.5e-20	31.9

DBSCAN-SWA_2

123021 : 184076

Escherichia_phage(42.22%)

portal,tRNA,head,terminase,lysis,tail,plate,integrase,transposase,holin,capsid

attL 127310:127336|attR 160189:160215

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000675148.1\|123021_124425_+	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	2.7e-33	29.4
WP_000137877.1\|124421_125144_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	3.7e-31	33.6
WP_000929408.1\|125323_125656_+	YegP family protein	NA	NA	NA	NA
WP_001520824.1\|125803_127165_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.6e-216	99.2
127310:127336	attL	NA	NA	NA	NA
WP_000468308.1\|127437_127656_-	prophage transcriptional regulator OgrK	A0A0F7LDQ9	Escherichia_phage	4.7e-38	100.0
WP_000882966.1\|127737_128901_-	phage late control D family protein	U5N3V4	Enterobacteria_phage	1.8e-205	99.7
WP_001565024.1\|128900_129380_-\|tail	phage tail protein	O64315	Escherichia_phage	9.6e-84	98.1
WP_021523174.1\|129394_131842_-\|tail	phage tail tape measure protein	M1T2S3	Escherichia_phage	0.0e+00	95.7
WP_000785970.1\|131834_131954_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.0e-15	100.0
WP_020233494.1\|131986_132262_-\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	2.2e-40	98.9
WP_001251412.1\|132318_132837_-\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	3.2e-93	99.4
WP_020233495.1\|132849_134040_-\|tail	phage tail sheath protein	A0A0F7LBW9	Escherichia_phage	9.0e-224	99.2
WP_032142943.1\|134369_134963_-	hypothetical protein	Q858S7	Enterobacteria_phage	1.0e-106	99.0
WP_021523177.1\|135184_135712_-\|tail	tail fiber assembly protein	A0A0C4UR05	Shigella_phage	4.9e-89	92.6
WP_021523178.1\|135713_137735_-\|tail	tail fiber protein	A0A0A7NV63	Enterobacteria_phage	2.7e-260	64.5
WP_001285325.1\|137745_138276_-\|tail	phage tail protein I	U5N0U8	Enterobacteria_phage	2.3e-102	100.0
WP_001121453.1\|138268_139177_-\|plate	baseplate assembly protein	U5N3T9	Enterobacteria_phage	4.4e-162	99.7
WP_000127164.1\|139181_139529_-\|plate	baseplate assembly protein	A0A0F7LDQ1	Escherichia_phage	1.3e-58	100.0
WP_020233499.1\|139525_140161_-\|plate	phage baseplate assembly protein V	U5N3F0	Enterobacteria_phage	1.2e-113	99.5
WP_021523179.1\|140244_141030_+	hypothetical protein	NA	NA	NA	NA
WP_001001802.1\|141101_141554_-	phage virion morphogenesis protein	A0A0F7LDR6	Escherichia_phage	1.5e-75	98.0
WP_000917186.1\|141546_142014_-\|tail	phage tail protein	Q7Y4E0	Escherichia_virus	2.5e-81	98.7
WP_072174950.1\|141976_142150_-\|lysis	phage lysis protein	Q7Y4E1	Escherichia_virus	9.8e-23	91.2
WP_001512906.1\|142121_142547_-\|lysis	LysB family phage lysis regulatory protein	Q858W0	Yersinia_virus	1.9e-67	98.6
WP_000736608.1\|142534_142960_-	hypothetical protein	U5N096	Enterobacteria_phage	2.3e-57	95.7
WP_001144101.1\|142974_143472_-	glycoside hydrolase family 104 protein	A0A0F7LBS0	Escherichia_phage	3.1e-93	100.0
WP_000123123.1\|143471_143753_-\|holin	holin	A0A0F7LA12	Escherichia_phage	1.3e-43	100.0
WP_000846399.1\|143756_143960_-\|tail	tail protein X	U5N3E7	Enterobacteria_phage	4.0e-31	100.0
WP_000988636.1\|143959_144469_-\|head	head completion/stabilization protein	A0A0F7LDJ1	Escherichia_phage	8.6e-91	100.0
WP_000203455.1\|144568_145312_-\|terminase	terminase endonuclease subunit	A0A0F7LDU4	Escherichia_phage	3.0e-124	99.2
WP_020233501.1\|145315_146389_-\|capsid	phage major capsid protein, P2 family	Q778Y7	Enterobacteria_phage	2.5e-201	99.2
WP_020233502.1\|146447_147302_-\|capsid	GPO family capsid scaffolding protein	Q778Z1	Enterobacteria_phage	8.1e-134	98.2
WP_000156847.1\|147475_149248_+\|terminase	terminase ATPase subunit family protein	A0A0F7LCM8	Escherichia_phage	0.0e+00	100.0
WP_001533791.1\|149247_150282_+\|portal	phage portal protein	A0A0F7LDI7	Escherichia_phage	2.7e-200	99.7
WP_124759995.1\|150320_150593_-	hypothetical protein	M1TAP7	Escherichia_phage	1.0e-18	94.3
WP_029401227.1\|150668_152093_+	histidine kinase	NA	NA	NA	NA
WP_029401228.1\|152089_153082_+	hypothetical protein	NA	NA	NA	NA
WP_029401229.1\|153032_154184_-	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	1.4e-32	31.2
WP_029701698.1\|156519_156795_-	DUF5405 family protein	U5N3W1	Enterobacteria_phage	1.5e-44	100.0
WP_029701699.1\|156791_157016_-	TraR/DksA family transcriptional regulator	A0A0F7LDG9	Escherichia_phage	3.8e-35	98.6
WP_001754915.1\|157015_157318_-	DUF5405 family protein	A0A0F7LCL4	Escherichia_phage	3.5e-47	100.0
WP_000557703.1\|157317_157542_-	DUF2732 family protein	S4TP68	Salmonella_phage	4.7e-33	100.0
WP_029701701.1\|157605_158106_-	hypothetical protein	S4TTB7	Salmonella_phage	1.9e-90	98.8
WP_029701703.1\|158283_158559_-	hypothetical protein	Q1JS60	Enterobacteria_phage	2.2e-48	98.9
WP_000020919.1\|158680_158980_+	helix-turn-helix domain-containing protein	Q1JS61	Enterobacteria_phage	2.4e-48	100.0
WP_087503482.1\|159095_160109_+\|integrase	tyrosine-type recombinase/integrase	Q83VS6	Escherichia_phage	2.7e-192	98.8
WP_023154000.1\|160206_160398_-	hypothetical protein	NA	NA	NA	NA
160189:160215	attR	NA	NA	NA	NA
WP_001303579.1\|160385_160703_-	hypothetical protein	NA	NA	NA	NA
WP_000807371.1\|161117_162017_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	4.8e-12	29.0
WP_000178552.1\|162098_162878_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_001520826.1\|162977_164018_-	galactitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_000490663.1\|164065_165421_-	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
WP_000823282.1\|165424_165709_-	PTS galactitol transporter subunit IIB	NA	NA	NA	NA
WP_000182900.1\|165739_166192_-	PTS galactitol transporter subunit IIA	NA	NA	NA	NA
WP_001308759.1\|167487_168342_-	tagatose-bisphosphate aldolase subunit GatY	NA	NA	NA	NA
WP_000129551.1\|168571_169624_-	class I fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_000858471.1\|169880_171158_+	MFS transporter	NA	NA	NA	NA
WP_001520828.1\|171154_172159_+	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	4.4e-14	29.7
WP_001520829.1\|172155_173121_+	kinase	NA	NA	NA	NA
WP_000434044.1\|173094_173841_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_020233504.1\|173892_174711_-	glycoside hydrolase family 25 protein	D0R7H8	Paenibacillus_phage	1.1e-23	38.0
WP_000822277.1\|174775_175576_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_001195594.1\|175572_176361_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_000019944.1\|176583_176856_-	Ni(II)/Co(II)-binding transcriptional repressor RcnR	NA	NA	NA	NA
WP_000134572.1\|176976_177801_+	nickel/cobalt efflux protein RcnA	NA	NA	NA	NA
WP_000153067.1\|178019_178358_+	Ni(II)/Co(II) efflux transporter accessory subunit RcnB	NA	NA	NA	NA
WP_000702203.1\|178439_179474_-	putative fimbrial-like adhesin protein	NA	NA	NA	NA
WP_001520833.1\|179489_181970_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_000677340.1\|181985_182660_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_000830468.1\|182740_183283_-	fimbrial protein	NA	NA	NA	NA
WP_000526135.1\|183617_184076_-\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

199547 : 208990

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001520842.1\|199547_200684_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	2.5e-162	97.4
WP_021523183.1\|200680_202681_+	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
WP_001295429.1\|202805_203267_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001295430.1\|203308_203779_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_000598641.1\|203825_204545_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001309587.1\|204541_206227_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	7.3e-304	99.5
WP_001240398.1\|206448_207180_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.8e-111	99.0
WP_001216963.1\|207239_207347_+	protein YohO	NA	NA	NA	NA
WP_000783145.1\|207327_208059_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_000569374.1\|208063_208990_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	4.8e-23	30.8

DBSCAN-SWA_4

421914 : 494540

Enterobacteria_phage(46.77%)

portal,tRNA,head,terminase,lysis,integrase,holin

attL 453594:453616|attR 502279:502301

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001283590.1\|421914_422727_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_001289165.1\|422726_423740_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000699144.1\|423805_424942_-	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	2.0e-23	29.1
WP_001520944.1\|425040_426036_+	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_000127789.1\|426032_427211_-	arabinose transporter	NA	NA	NA	NA
WP_000817178.1\|427486_428707_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_001520946.1\|428865_430872_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_000559764.1\|430927_431206_-	YfcL family protein	NA	NA	NA	NA
WP_001089216.1\|431239_431788_-	elongation factor P hydroxylase	NA	NA	NA	NA
WP_001520948.1\|431787_432597_-	TSUP family transporter	NA	NA	NA	NA
WP_001043827.1\|432596_433421_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_001297933.1\|433424_434510_-	chorismate synthase	A0A291AU41	Pandoravirus	7.0e-90	47.8
WP_001309606.1\|434544_435477_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_000730805.1\|435642_436194_+	endonuclease SmrB	NA	NA	NA	NA
WP_001520950.1\|436263_437127_-	DUF2544 domain-containing protein	NA	NA	NA	NA
WP_001037531.1\|437128_437674_-	fimbrial protein	NA	NA	NA	NA
WP_000826833.1\|437670_438150_-	fimbrial protein	NA	NA	NA	NA
WP_000826023.1\|438146_438638_-	fimbrial protein	NA	NA	NA	NA
WP_000170521.1\|438653_439403_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_020232969.1\|439422_442062_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_000033306.1\|442145_442712_-	fimbrial protein	NA	NA	NA	NA
WP_001195819.1\|443373_443859_-	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_000425037.1\|444061_446206_-	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_000531924.1\|446205_447516_-	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_001296261.1\|447696_447981_-	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_001520953.1\|448352_449693_+	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_001520954.1\|450058_451306_+	hypothetical protein	NA	NA	NA	NA
WP_000776768.1\|451484_452240_-	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_000368131.1\|452533_453466_+	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
453594:453616	attL	NA	NA	NA	NA
WP_087503470.1\|453777_454935_+\|integrase	prophage integrase IntS	A5VW56	Enterobacteria_phage	3.7e-222	99.2
WP_100249830.1\|455051_455744_-	hypothetical protein	NA	NA	NA	NA
WP_050596990.1\|455708_456440_+	hypothetical protein	NA	NA	NA	NA
WP_087503469.1\|456559_458959_-\|head	phage head protein	A5VW57	Enterobacteria_phage	8.0e-78	90.6
WP_087503468.1\|459123_461517_-	lytic transglycosylase domain-containing protein	Q716G2	Shigella_phage	0.0e+00	96.8
WP_087503467.1\|461517_462849_-	acyltransferase	A0A2D1GLX5	Escherichia_phage	5.5e-214	98.2
WP_087503466.1\|462858_463551_-	DNA transfer protein	G5DA80	Enterobacteria_phage	2.7e-111	99.6
WP_087503465.1\|463553_464009_-	DUF2824 family protein	A5VW67	Enterobacteria_phage	2.8e-85	97.4
WP_087503464.1\|464008_464962_-	hypothetical protein	Q716G6	Shigella_phage	5.4e-94	84.9
WP_085701391.1\|464961_466380_-	hypothetical protein	Q9AYZ4	Salmonella_phage	2.3e-274	98.7
WP_000246750.1\|466388_466871_-	packaged DNA stabilization protein p27	Q716G8	Shigella_phage	3.8e-88	100.0
WP_000375637.1\|466845_467031_-	hypothetical protein	Q716G9	Shigella_phage	2.7e-26	100.0
WP_060579115.1\|467073_468345_-\|head	head protein	Q9AYZ7	Salmonella_phage	7.3e-240	99.5
WP_000426735.1\|468356_469241_-	hypothetical protein	Q716H1	Shigella_phage	8.1e-145	99.7
WP_000852333.1\|469254_471381_-\|portal	portal protein p19	Q9AYZ9	Salmonella_phage	0.0e+00	99.6
WP_060579116.1\|471383_472796_-\|terminase	PBSX family phage terminase large subunit	Q716H3	Shigella_phage	5.8e-278	99.8
WP_001436504.1\|472792_473215_-	hypothetical protein	Q716H4	Shigella_phage	7.2e-75	100.0
WP_031624844.1\|473238_473418_-	hypothetical protein	Q9AZ02	Salmonella_phage	1.2e-23	93.2
WP_001700895.1\|473427_473715_-	hypothetical protein	I1TQD4	Pseudomonas_phage	1.3e-06	33.3
WP_000807789.1\|473718_473961_-	DUF2560 family protein	A5VW77	Enterobacteria_phage	3.7e-36	100.0
WP_001058931.1\|474209_474695_-	GIY-YIG nuclease family protein	C6ZR70	Salmonella_phage	8.5e-88	100.0
WP_021568311.1\|474900_475053_-	hypothetical protein	Q716B2	Shigella_phage	3.1e-20	94.0
WP_063123791.1\|475040_475508_-\|lysis	lysis protein	A0A291AWW3	Escherichia_phage	1.5e-73	95.5
WP_000229389.1\|475504_475981_-	glycoside hydrolase family protein	A5VW81	Enterobacteria_phage	7.5e-89	100.0
WP_000783734.1\|475964_476288_-\|holin	phage holin, lambda family	G5DA93	Enterobacteria_phage	1.3e-52	100.0
WP_000027554.1\|476883_477402_-	DUF1133 family protein	Q716B8	Shigella_phage	5.9e-95	99.4
WP_000994516.1\|477398_477587_-	protein ninH	A5VW84	Enterobacteria_phage	5.5e-27	100.0
WP_001549462.1\|477583_477946_-	RusA family crossover junction endodeoxyribonuclease	K7PJW5	Enterobacteria_phage	6.6e-61	97.5
WP_023146907.1\|477946_478471_-	HNH endonuclease	K4F9R1	Cronobacter_phage	7.1e-32	42.9
WP_000002250.1\|478467_478758_-	DUF1364 domain-containing protein	Q9MCN9	Enterobacteria_phage	3.4e-52	100.0
WP_023146906.1\|478757_479480_-	phage antirepressor protein	K7P7L0	Enterobacteria_phage	1.1e-128	97.5
WP_000566866.1\|479472_479643_-	protein ninF	K7PLU6	Enterobacteria_phage	2.5e-26	100.0
WP_024176095.1\|479639_479822_-	NinE family protein	Q8H9Z6	Enterobacteria_phage	1.3e-28	98.3
WP_023146905.1\|479818_480346_-	phage N-6-adenine-methyltransferase	A0A1I9LJP9	Stx_converting_phage	1.2e-100	99.4
WP_000736913.1\|480342_480783_-	recombination protein NinB	M1FPM8	Enterobacteria_phage	1.2e-80	100.0
WP_001749476.1\|480856_482233_-	AAA family ATPase	A0A0P0ZC27	Stx2-converting_phage	1.6e-253	99.8
WP_087503463.1\|482229_483177_-	replication protein	A5VW95	Enterobacteria_phage	5.1e-153	98.4
WP_001244621.1\|483179_483452_-	hypothetical protein	G9L679	Escherichia_phage	2.7e-43	100.0
WP_000251072.1\|483474_483768_-	hypothetical protein	A5VW96	Enterobacteria_phage	1.7e-46	100.0
WP_001194218.1\|483887_484103_-	helix-turn-helix transcriptional regulator	Q716D6	Shigella_phage	1.4e-31	100.0
WP_000028392.1\|484206_484839_+	LexA family transcriptional regulator	K7P850	Enterobacteria_phage	1.6e-118	99.5
WP_000618034.1\|484835_485240_+	hypothetical protein	Q716D7	Shigella_phage	2.1e-68	96.2
WP_077694523.1\|485489_485870_+	antitermination protein	A4KWR0	Enterobacteria_phage	5.3e-53	99.1
WP_000213975.1\|485948_486149_+	Restriction inhibitor protein ral	A0A0K2FJE6	Enterobacteria_phage	1.4e-33	100.0
WP_000972063.1\|486375_486510_+	hypothetical protein	K7PHK2	Enterobacteria_phage	3.1e-16	100.0
WP_001243355.1\|486494_486647_+	host cell division inhibitory peptide Kil	A5VWA5	Enterobacteria_phage	4.7e-21	100.0
WP_000604111.1\|486731_487040_+	hypothetical protein	K7PJM4	Enterobacteria_phage	1.1e-53	100.0
WP_032153682.1\|487036_487948_+	DNA recombinase	K7PKG9	Enterobacteria_phage	2.4e-168	98.7
WP_032153683.1\|487931_488414_+	siphovirus Gp157 family protein	K7P6T5	Enterobacteria_phage	6.1e-78	97.5
WP_000753555.1\|488425_488740_+	hypothetical protein	K7PLT4	Enterobacteria_phage	1.2e-50	100.0
WP_029701300.1\|488756_489038_+	hypothetical protein	K7P7M4	Enterobacteria_phage	2.8e-43	96.8
WP_032153684.1\|489034_489202_+	DUF2737 family protein	Q716F2	Shigella_phage	5.0e-24	98.2
WP_029701301.1\|489198_489453_+	hypothetical protein	A0A1V0E5L1	Salmonella_phage	3.2e-38	95.2
WP_029701302.1\|489439_490132_+	ead/Ea22-like family protein	A0A088CC42	Shigella_phage	1.2e-82	55.4
WP_000951706.1\|490133_490343_+	hypothetical protein	A0A077SL56	Escherichia_phage	4.2e-36	100.0
WP_029701304.1\|490339_491131_+	DUF551 domain-containing protein	A0A0H4IU61	Shigella_phage	1.0e-58	51.8
WP_029701309.1\|491123_491408_+	RNA-binding protein	A0A2D1GLL3	Escherichia_phage	9.4e-47	94.7
WP_000545716.1\|491479_491647_+	hypothetical protein	K7P728	Enterobacteria_phage	9.2e-26	92.7
WP_001163428.1\|491704_491905_+	response regulator inhibitor TorI	K7P7V0	Enterobacteria_phage	2.4e-33	100.0
WP_001535474.1\|492157_493444_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.1e-65	37.3
WP_001706457.1\|493445_494192_+	hypothetical protein	NA	NA	NA	NA
WP_000749077.1\|494348_494540_+	AlpA family transcriptional regulator	E5E3Y1	Burkholderia_phage	4.2e-06	49.0
502279:502301	attR	NA	NA	NA	NA

DBSCAN-SWA_5

870311 : 877451

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001272917.1\|870311_872873_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	9.2e-32	20.8
WP_001141345.1\|872978_873635_+	protein-serine/threonine phosphatase	A0A077SLQ6	Escherichia_phage	5.0e-51	47.0
WP_001295181.1\|873685_874453_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.5e-70	56.7
WP_000847993.1\|874648_875557_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.1e-117	76.5
WP_001521147.1\|875553_876816_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_001278994.1\|876812_877451_+	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0

DBSCAN-SWA_6

3715858 : 3772060

Enterobacteria_phage(36.21%)

portal,head,terminase,tail,integrase,transposase,holin,protease,capsid

attL 3707968:3707984|attR 3749317:3749333

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3707968:3707984	attL	NA	NA	NA	NA
WP_001540845.1\|3715858_3716929_-\|integrase	tyrosine-type recombinase/integrase	Q9MCR4	Enterobacteria_phage	9.6e-201	99.4
WP_001303849.1\|3716906_3717125_-	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000545741.1\|3717164_3717332_-	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	4.9e-27	98.2
WP_072196869.1\|3717264_3717468_+	hypothetical protein	NA	NA	NA	NA
WP_060578272.1\|3717432_3718311_-	DUF551 domain-containing protein	A0A0H4IU61	Shigella_phage	6.7e-67	53.4
WP_000951710.1\|3718307_3718517_-	hypothetical protein	A0A0F6TJE4	Escherichia_coli_O157_typing_phage	8.8e-34	94.2
WP_060578271.1\|3718518_3718707_-	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	2.9e-28	93.5
WP_060578270.1\|3718879_3719374_-	ead/Ea22-like family protein	A0A0P0ZD75	Stx2-converting_phage	3.0e-24	55.0
WP_029701301.1\|3719360_3719615_-	hypothetical protein	A0A1V0E5L1	Salmonella_phage	3.2e-38	95.2
WP_032153684.1\|3719611_3719779_-	DUF2737 family protein	Q716F2	Shigella_phage	5.0e-24	98.2
WP_029701300.1\|3719775_3720057_-	hypothetical protein	K7P7M4	Enterobacteria_phage	2.8e-43	96.8
WP_000753555.1\|3720073_3720388_-	hypothetical protein	K7PLT4	Enterobacteria_phage	1.2e-50	100.0
WP_060578269.1\|3720399_3720882_-	siphovirus Gp157 family protein	K7P6T5	Enterobacteria_phage	2.3e-77	96.2
WP_000065840.1\|3720865_3721777_-	DNA recombinase	K7PKG9	Enterobacteria_phage	1.1e-168	99.3
WP_000604110.1\|3721773_3722082_-	hypothetical protein	K7PJM4	Enterobacteria_phage	3.3e-53	99.0
WP_001308813.1\|3722166_3722442_-	hypothetical protein	K7PGS9	Enterobacteria_phage	1.6e-46	100.0
WP_060578268.1\|3722563_3722764_-	restriction endonuclease	A0A0K2FJE6	Enterobacteria_phage	4.2e-33	98.5
WP_032194733.1\|3722892_3723165_-	hypothetical protein	A0A0N7C217	Escherichia_phage	2.2e-40	97.8
WP_048970231.1\|3723615_3724299_-	hypothetical protein	NA	NA	NA	NA
WP_000433877.1\|3724298_3724619_-	hypothetical protein	NA	NA	NA	NA
WP_002431456.1\|3724742_3725450_-	helix-turn-helix transcriptional regulator	G9L676	Escherichia_phage	4.3e-133	99.6
WP_001180317.1\|3725529_3725757_+	transcriptional regulator	G9L677	Escherichia_phage	1.7e-35	98.7
WP_000442611.1\|3725895_3726192_+	hypothetical protein	A0A1U9AJB5	Stx1_converting_phage	1.5e-47	98.0
WP_000185505.1\|3726224_3727124_+	replication protein	A0A0K2FJ31	Enterobacteria_phage	3.8e-174	100.0
WP_000788893.1\|3727120_3727822_+	hypothetical protein	A0A0K2FIT1	Enterobacteria_phage	6.4e-129	99.1
WP_000145931.1\|3727818_3728109_+	protein ren	A0A1I9LJP5	Stx_converting_phage	9.6e-47	100.0
WP_000736913.1\|3728182_3728623_+	recombination protein NinB	M1FPM8	Enterobacteria_phage	1.2e-80	100.0
WP_001254257.1\|3728619_3728802_+	NinE family protein	A0A0P0ZC71	Stx2-converting_phage	4.3e-29	100.0
WP_000566869.1\|3728798_3728969_+	protein ninF	Q8H9Z5	Enterobacteria_phage	3.5e-25	96.4
WP_001108039.1\|3728961_3729573_+	recombination protein NinG	Q716C3	Shigella_phage	2.7e-99	100.0
WP_000512806.1\|3729616_3730105_+	late gene antiterminator protein	M1FPN0	Enterobacteria_phage	5.3e-90	100.0
WP_000839572.1\|3730470_3730686_+\|holin	holin	M1FN85	Enterobacteria_phage	5.3e-34	98.6
WP_000193280.1\|3730690_3731041_+	YdfR family protein	K7PGU6	Enterobacteria_phage	2.9e-37	95.2
WP_000992100.1\|3731104_3731638_+	lysozyme	Q08J98	Stx2-converting_phage	3.6e-100	94.4
WP_001228685.1\|3731854_3732040_+	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	6.4e-20	80.3
WP_001100260.1\|3732257_3732524_+	hypothetical protein	NA	NA	NA	NA
WP_001532432.1\|3732529_3733069_-	hypothetical protein	NA	NA	NA	NA
WP_001532429.1\|3733207_3733558_+	HNH endonuclease	A0A1B5FP94	Escherichia_phage	1.4e-63	96.6
WP_023153903.1\|3733705_3734188_+\|terminase	phage terminase small subunit P27 family	A0A1B5FPA0	Escherichia_phage	4.3e-84	97.5
WP_001140892.1\|3734187_3735945_+\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	0.0e+00	99.3
WP_001735009.1\|3736092_3737319_+\|portal	phage portal protein	Q8SBI0	Shigella_phage	3.1e-203	82.8
WP_000999828.1\|3737311_3737911_+\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	1.9e-89	81.0
WP_000766108.1\|3737925_3739143_+\|capsid	phage major capsid protein	A0A1W6JP20	Morganella_phage	1.7e-161	71.4
WP_000719066.1\|3739219_3739537_+\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	6.2e-23	50.5
WP_001147814.1\|3739545_3739884_+\|head	phage head closure protein	A0A1B5FP90	Escherichia_phage	7.5e-51	90.2
WP_014639219.1\|3739880_3740330_+	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	1.0e-63	80.5
WP_001546001.1\|3740326_3740671_+	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	2.3e-55	96.5
WP_000097524.1\|3740731_3741436_+	hypothetical protein	A0A1B5FP82	Escherichia_phage	1.7e-113	93.6
WP_001324129.1\|3741435_3741822_+\|tail	tail assembly protein	A0A1B5FP91	Escherichia_phage	8.9e-64	100.0
WP_077628067.1\|3741863_3742124_+	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	1.7e-39	96.5
WP_032180049.1\|3742170_3745398_+\|tail	phage tail tape measure protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	95.6
WP_001330090.1\|3745375_3745732_+\|tail	tail protein	A0A0P0ZDL9	Stx2-converting_phage	2.8e-40	66.7
WP_001735013.1\|3745731_3746430_+\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	7.6e-130	97.0
WP_047626242.1\|3746435_3747179_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	5.0e-148	97.6
WP_000741589.1\|3747076_3747724_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.9e-111	97.2
WP_087565616.1\|3747784_3751264_+	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	89.8
3749317:3749333	attR	NA	NA	NA	NA
WP_001228314.1\|3751331_3751931_+	Ail/Lom family protein	Q9EV15	Enterobacteria_phage	9.1e-108	97.0
WP_108161041.1\|3752082_3754455_+\|tail	phage tail protein	A0A1X7QGG5	Escherichia_phage	1.8e-167	69.0
WP_000654155.1\|3754454_3754736_+	hypothetical protein	A0A1X7QHA1	Escherichia_phage	1.4e-18	50.0
WP_001314683.1\|3754745_3755786_+\|tail	tail fiber domain-containing protein	A0A0E3M4A9	Enterobacteria_phage	2.9e-125	67.9
WP_087503547.1\|3755828_3756122_+	hypothetical protein	NA	NA	NA	NA
WP_087503546.1\|3756334_3757666_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.4e-20	37.1
WP_000767391.1\|3758411_3758888_-	kinase inhibitor	NA	NA	NA	NA
WP_001309367.1\|3758946_3760236_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	1.0e-18	29.0
WP_000951213.1\|3760322_3761363_+	biotin synthase BioB	NA	NA	NA	NA
WP_021517032.1\|3761359_3762514_+	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_000246795.1\|3762500_3763256_+	malonyl-ACP O-methyltransferase BioC	NA	NA	NA	NA
WP_000044837.1\|3763248_3763926_+	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_000042533.1\|3764504_3766526_+	excinuclease ABC subunit B	NA	NA	NA	NA
WP_001522645.1\|3766563_3767472_-	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	3.2e-27	30.7
WP_001295301.1\|3767868_3768858_+	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_000084639.1\|3768879_3769392_+	molybdenum cofactor biosynthesis protein B	NA	NA	NA	NA
WP_000080885.1\|3769394_3769880_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_000598612.1\|3769872_3770118_+	molybdopterin synthase sulfur carrier subunit	NA	NA	NA	NA
WP_000852287.1\|3770119_3770572_+	molybdopterin synthase catalytic subunit MoaE	NA	NA	NA	NA
WP_001522649.1\|3770708_3771413_+	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_000526135.1\|3771601_3772060_+\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

4118258 : 4191650

Escherichia_phage(36.84%)

portal,tRNA,head,terminase,lysis,tail,integrase,transposase,holin,capsid

attL 4119386:4119401|attR 4164094:4164109

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000526135.1\|4118258_4118717_+\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_000598207.1\|4118838_4119798_-	L,D-transpeptidase LdtC	NA	NA	NA	NA
4119386:4119401	attL	NA	NA	NA	NA
WP_024166502.1\|4119944_4123391_-	transcription-repair coupling factor	NA	NA	NA	NA
WP_001522877.1\|4123518_4124592_-	acyltransferase family protein	NA	NA	NA	NA
WP_000284714.1\|4124852_4126052_+	lipoprotein-releasing ABC transporter permease subunit LolC	NA	NA	NA	NA
WP_001033689.1\|4126044_4126746_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	5.4e-35	39.8
WP_001251363.1\|4126745_4127990_+	lipoprotein-releasing ABC transporter permease subunit LolE	NA	NA	NA	NA
WP_000291248.1\|4128018_4128930_+	N-acetylglucosamine kinase	NA	NA	NA	NA
WP_000952736.1\|4128945_4129767_+	NAD-dependent protein deacylase	A0A2I7S9Y2	Vibrio_phage	5.6e-23	35.6
WP_000720604.1\|4129903_4130689_-	hypothetical protein	NA	NA	NA	NA
WP_001522885.1\|4130685_4131147_-	DUF3592 domain-containing protein	NA	NA	NA	NA
WP_000759309.1\|4131204_4132251_-	spermidine/putrescine ABC transporter substrate-binding protein PotD	NA	NA	NA	NA
WP_000580316.1\|4132247_4133042_-	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
WP_000074983.1\|4133208_4134327_-\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	7.7e-84	44.2
WP_000003742.1\|4134295_4134565_-	excisionase	NA	NA	NA	NA
WP_001542183.1\|4134626_4137083_-	exonuclease	V5UQJ3	Shigella_phage	2.5e-103	42.6
WP_001093951.1\|4137160_4137364_-	DUF1482 family protein	NA	NA	NA	NA
WP_000450218.1\|4137360_4137549_-	cell division inhibitor	NA	NA	NA	NA
WP_000935596.1\|4137559_4138414_-	hypothetical protein	A0A0P0ZE80	Stx2-converting_phage	3.6e-65	63.2
WP_000394557.1\|4138944_4139319_-	hypothetical protein	NA	NA	NA	NA
WP_000379564.1\|4139330_4139483_-	DUF1391 family protein	NA	NA	NA	NA
WP_000787428.1\|4139689_4140097_-	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	9.8e-29	49.6
WP_000912294.1\|4140173_4140401_+	transcriptional regulator	NA	NA	NA	NA
WP_000705383.1\|4140384_4140936_+	hypothetical protein	NA	NA	NA	NA
WP_000020541.1\|4140907_4141948_+	DNA-binding protein	A0A0U2RT81	Escherichia_phage	1.0e-90	87.2
WP_148240174.1\|4141979_4142402_+	replication protein	A0A0U2JGJ0	Escherichia_phage	2.8e-71	89.3
WP_000450706.1\|4142435_4143206_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.1e-86	68.4
WP_001141099.1\|4143221_4143614_+	DUF977 family protein	A0A088CBK9	Shigella_phage	1.5e-39	63.3
WP_001266130.1\|4143610_4143907_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	1.2e-47	95.8
WP_001209475.1\|4143903_4144365_+	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	2.6e-38	94.0
WP_000403791.1\|4144342_4144699_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.1e-57	98.3
WP_000137948.1\|4144794_4145202_+	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	1.0e-22	60.4
WP_001229301.1\|4145203_4145569_+	HNH endonuclease	A0A2R2Z2X9	Escherichia_phage	1.9e-68	99.2
WP_000208092.1\|4145565_4146552_+	hypothetical protein	Q1MVF7	Enterobacteria_phage	1.8e-44	41.5
WP_000786207.1\|4146672_4146852_+	hypothetical protein	NA	NA	NA	NA
WP_000813254.1\|4147110_4147266_+	type I toxin-antitoxin system toxin HokD	A0A0U2QV81	Escherichia_phage	1.5e-17	96.1
WP_001309416.1\|4147482_4147734_+	hypothetical protein	NA	NA	NA	NA
WP_001309417.1\|4147800_4148079_+	hypothetical protein	I6PCV7	Cronobacter_phage	6.3e-11	45.3
WP_001265256.1\|4148080_4149139_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.8e-90	48.3
WP_000140038.1\|4149139_4149508_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.4e-34	62.8
WP_001064909.1\|4149500_4150190_+	antiterminator	I6PDF8	Cronobacter_phage	7.1e-56	48.1
WP_001309418.1\|4150402_4150600_+	hypothetical protein	S5MQK8	Escherichia_phage	1.7e-26	93.8
WP_000871291.1\|4150969_4151305_-	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	5.2e-44	74.8
WP_001309419.1\|4151550_4151754_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	2.7e-27	96.8
WP_000284506.1\|4152061_4152277_+\|holin	holin	Q9ZWW2	Enterobacteria_phage	6.9e-34	100.0
WP_001037014.1\|4152281_4153172_+	YdfR family protein	Q08JA0	Stx2-converting_phage	2.1e-108	70.9
WP_001092866.1\|4153208_4153742_+	lysozyme	Q6H9V6	Enterobacteria_phage	6.7e-102	97.2
WP_001322430.1\|4153684_4153900_-	hypothetical protein	Q8VNN9	Enterobacteria_phage	1.1e-23	90.2
WP_001446668.1\|4153898_4154081_+	hypothetical protein	NA	NA	NA	NA
WP_001280932.1\|4154095_4154227_+	hypothetical protein	A0A0P0ZG36	Escherichia_phage	2.6e-07	79.1
WP_032142285.1\|4154229_4154697_+\|lysis	lysis protein	Q6H9V3	Enterobacteria_phage	6.7e-66	84.4
WP_000830178.1\|4155007_4155334_+	TonB family protein	H6WZK5	Escherichia_phage	3.7e-39	72.2
WP_001322427.1\|4155456_4155810_-	hypothetical protein	NA	NA	NA	NA
WP_012602757.1\|4155697_4156018_-	hypothetical protein	NA	NA	NA	NA
WP_000235436.1\|4156292_4156802_+\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_001309424.1\|4156773_4158702_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.4e-261	66.4
WP_000258993.1\|4158685_4158892_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	3.0e-10	55.4
WP_001322425.1\|4158888_4160481_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	4.9e-185	61.1
WP_001253888.1\|4160470_4161976_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.0e-99	53.1
WP_000256814.1\|4162012_4162360_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	6.8e-23	59.1
WP_029702099.1\|4162417_4163446_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	4.1e-116	61.9
WP_000201530.1\|4163497_4163872_+	hypothetical protein	NA	NA	NA	NA
WP_001204533.1\|4163864_4164218_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	1.9e-41	70.1
4164094:4164109	attR	NA	NA	NA	NA
WP_087503545.1\|4164233_4164809_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.6e-48	56.8
WP_000683079.1\|4164805_4165201_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	1.5e-58	82.4
WP_000235111.1\|4165208_4165961_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	2.7e-133	98.0
WP_000479111.1\|4165974_4166406_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	1.8e-41	68.1
WP_000533402.1\|4166432_4166846_+\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_000082417.1\|4166826_4169388_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	87.5
WP_000847298.1\|4169384_4169714_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_001328631.1\|4169713_4170412_+\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	3.2e-128	97.0
WP_000194723.1\|4170422_4171166_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	5.0e-148	98.0
WP_032300536.1\|4171111_4171744_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	4.2e-103	91.8
WP_000559722.1\|4171765_4172107_+	hypothetical protein	NA	NA	NA	NA
WP_000514726.1\|4172087_4175780_+	DUF1983 domain-containing protein	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	86.0
WP_001233148.1\|4175847_4176447_+	Ail/Lom family protein	H6WZM8	Escherichia_phage	7.7e-107	94.0
WP_000216486.1\|4176598_4179625_+	membrane protein	A0A0K2FIZ6	Escherichia_phage	1.4e-55	54.6
WP_000885577.1\|4179624_4180209_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	6.6e-103	94.8
WP_001309429.1\|4180181_4180319_+	hypothetical protein	NA	NA	NA	NA
WP_000240999.1\|4180263_4180932_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000937481.1\|4180988_4181255_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.5e-17	81.8
WP_000799406.1\|4181486_4182350_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000531594.1\|4182333_4183470_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
WP_001522887.1\|4183719_4184946_+	peptidase T	NA	NA	NA	NA
WP_000456506.1\|4184994_4186116_-	cupin domain-containing protein	NA	NA	NA	NA
WP_000735412.1\|4186191_4187652_-	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_001265481.1\|4187651_4188323_-	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000423742.1\|4188492_4189863_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.2e-107	44.9
WP_001297479.1\|4189866_4190508_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000004751.1\|4190543_4191650_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA

DBSCAN-SWA_8

4617398 : 4680675

Enterobacteria_phage(41.82%)

portal,head,terminase,lysis,tail,integrase,transposase,capsid

attL 4648252:4648267|attR 4685371:4685386

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000527786.1\|4617398_4618859_-	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	5.1e-43	29.7
WP_029701979.1\|4618947_4620231_-	MHS family MFS transporter	NA	NA	NA	NA
WP_120795384.1\|4620834_4620948_+	Rac prophage; protein YnaM	A0A1C9IHU6	Salmonella_phage	8.4e-07	80.6
WP_000836768.1\|4621016_4621250_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
WP_000086527.1\|4621566_4622157_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-24	38.8
WP_000355609.1\|4622384_4622678_-	hypothetical protein	NA	NA	NA	NA
WP_000235967.1\|4622688_4623393_-\|tail	tail fiber domain-containing protein	A0A1X7QGH6	Escherichia_phage	1.2e-58	61.7
WP_000654154.1\|4623402_4623684_-	hypothetical protein	A0A1X7QHA1	Escherichia_phage	1.2e-17	47.8
WP_032152843.1\|4623680_4626080_-\|tail	phage tail protein	A0A0E3M194	Enterobacteria_phage	3.9e-133	55.3
WP_001542091.1\|4626144_4626744_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	9.8e-102	91.5
WP_021523093.1\|4626811_4630291_-	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	89.6
WP_049286672.1\|4630351_4630954_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	8.1e-88	85.6
WP_032153655.1\|4630890_4631634_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	9.5e-147	96.7
WP_029702161.1\|4631639_4632338_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	8.9e-131	97.4
WP_000847345.1\|4632337_4632667_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	8.1e-58	98.2
WP_048219008.1\|4632663_4635225_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	96.0
WP_000459457.1\|4635217_4635652_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479153.1\|4635633_4636056_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	6.7e-73	100.0
WP_001349920.1\|4636071_4636812_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	7.8e-133	100.0
WP_000683128.1\|4636819_4637215_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	6.5e-70	99.2
WP_000975070.1\|4637211_4637790_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	2.7e-80	100.0
WP_000752979.1\|4637801_4638155_-\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	2.0e-62	100.0
WP_020233914.1\|4638166_4638565_-	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	2.3e-62	98.5
WP_000063277.1\|4638606_4639632_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	2.7e-192	99.7
WP_001708751.1\|4639686_4640019_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
WP_020233915.1\|4640028_4641348_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	2.2e-231	97.7
WP_001356819.1\|4641328_4642930_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.1e-309	99.2
WP_000198149.1\|4642926_4643133_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001027269.1\|4643129_4645055_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.5
WP_000453587.1\|4645029_4645575_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_001368374.1\|4645963_4646197_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	2.5e-21	84.1
WP_000373090.1\|4646254_4646665_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	2.5e-56	79.4
WP_001019606.1\|4646816_4646990_-	addiction module toxin, GnsA/GnsB family	NA	NA	NA	NA
WP_001309517.1\|4647161_4647317_-	hypothetical protein	NA	NA	NA	NA
WP_120795388.1\|4647396_4647462_-	Qin prophage; protein YnfR	NA	NA	NA	NA
WP_071524604.1\|4647464_4647653_-	cold-shock protein	NA	NA	NA	NA
WP_000066495.1\|4647663_4647876_-	cold shock protein CspI	A0A1W6JNX5	Morganella_phage	1.2e-22	74.3
WP_001071769.1\|4648238_4648736_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	2.9e-06	29.5
4648252:4648267	attL	NA	NA	NA	NA
WP_001092971.1\|4648732_4649266_-	lysozyme	K7PLY1	Enterobacteria_phage	6.4e-97	93.2
WP_000189916.1\|4649262_4649574_-	YdfR family protein	K7PGU6	Enterobacteria_phage	2.0e-26	64.6
WP_000839590.1\|4649578_4649794_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	1.1e-31	94.4
WP_000526135.1\|4650350_4650809_-\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_000066484.1\|4651259_4651475_-	cold shock-like protein CspB	A0A1W6JNX5	Morganella_phage	3.4e-25	76.5
WP_000087756.1\|4651775_4651988_+	cold shock-like protein CspF	NA	NA	NA	NA
WP_120795389.1\|4652042_4652132_+	Qin prophage; protein YnfS	NA	NA	NA	NA
WP_001047135.1\|4652409_4653162_-	antitermination protein	A0A192Y5X6	Salmonella_phage	7.1e-134	92.8
WP_001265199.1\|4653175_4654225_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	2.8e-112	57.0
WP_012304870.1\|4654226_4654505_-	hypothetical protein	NA	NA	NA	NA
WP_000980994.1\|4654571_4654823_-	hypothetical protein	NA	NA	NA	NA
WP_000813254.1\|4655039_4655195_-	type I toxin-antitoxin system toxin HokD	A0A0U2QV81	Escherichia_phage	1.5e-17	96.1
WP_000323025.1\|4655266_4655554_-	type II toxin-antitoxin system mRNA interferase RelE	A0A2H4JBF4	uncultured_Caudovirales_phage	1.4e-29	66.0
WP_000534858.1\|4655553_4655793_-	type II toxin-antitoxin system antitoxin RelB	A0A2H4JBG1	uncultured_Caudovirales_phage	1.6e-18	54.4
WP_001326990.1\|4655817_4656123_+	hypothetical protein	NA	NA	NA	NA
WP_001301033.1\|4656325_4656658_+	protein FlxA	NA	NA	NA	NA
WP_000589005.1\|4657094_4658408_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_001345551.1\|4658891_4659920_-	DUF4868 domain-containing protein	NA	NA	NA	NA
WP_001265627.1\|4659916_4660531_-	hypothetical protein	NA	NA	NA	NA
WP_021523102.1\|4660739_4661405_-	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_001151242.1\|4661607_4662006_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	7.7e-63	93.9
WP_000054487.1\|4662046_4663012_-	hypothetical protein	U5P0A0	Shigella_phage	2.6e-56	60.8
WP_000705355.1\|4662992_4663514_-	hypothetical protein	NA	NA	NA	NA
WP_000921596.1\|4663497_4663725_-	transcriptional regulator	NA	NA	NA	NA
WP_000381212.1\|4663805_4664213_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	7.2e-32	51.9
WP_000379575.1\|4664381_4664537_+	DUF1391 family protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_148240173.1\|4664538_4665114_+	hypothetical protein	NA	NA	NA	NA
WP_000854559.1\|4665600_4665789_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001083276.1\|4665785_4665977_+\|lysis	lysis protein YdfD	NA	NA	NA	NA
WP_000048363.1\|4666070_4668542_+	exonuclease	A0A192Y6E0	Salmonella_phage	1.2e-57	56.1
WP_001296941.1\|4668629_4668866_+	excisionase family protein	S4TND0	Salmonella_phage	6.1e-15	50.7
WP_077882484.1\|4668858_4668960_-	copper resistance protein	NA	NA	NA	NA
WP_001339397.1\|4668936_4669614_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|4669613_4669961_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_087565618.1\|4669980_4671552_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.2e-168	58.3
WP_021523105.1\|4671607_4672888_+\|integrase	site-specific integrase	B6DZ48	Enterobacteria_phage	3.9e-156	62.6
WP_001389342.1\|4672889_4673018_-	hypothetical protein	NA	NA	NA	NA
WP_000836037.1\|4673075_4674095_-	Zn-dependent oxidoreductase	E3SJ82	Synechococcus_phage	4.3e-17	26.2
WP_001295394.1\|4674106_4675321_-	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	1.4e-46	29.0
WP_001314753.1\|4675526_4675853_-	YnfA family protein	A0A218MNG8	uncultured_virus	2.2e-23	54.5
WP_000705205.1\|4675987_4676329_+	DUF1283 family protein	NA	NA	NA	NA
WP_001138584.1\|4676363_4676924_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_001445899.1\|4676926_4677637_-	YnfC family lipoprotein	NA	NA	NA	NA
WP_001295396.1\|4677744_4678050_+	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_001551145.1\|4678248_4680675_+	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	1.7e-213	49.2
4685371:4685386	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP022228

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 92111

114

Escherichia_phage(87.74%)

holin,tail,head,transposase,portal,integrase,plate

attL 607:621|attR 64752:64766

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
607:621	attL	NA	NA	NA	NA
WP_001408980.1\|759_960_+	hypothetical protein	NA	NA	NA	NA
WP_032153798.1\|962_1214_+	DNA polymerase III subunit theta	A0A077SLL5	Escherichia_phage	1.6e-37	97.6
WP_032153799.1\|1337_1727_+	DNA repair protein	A0A077SK24	Escherichia_phage	3.5e-68	95.3
WP_001190712.1\|1799_2021_+	type II toxin-antitoxin system Phd/YefM family antitoxin	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
WP_001216041.1\|2020_2401_+	type II toxin-antitoxin system death-on-curing family toxin	Q71T66	Escherichia_phage	6.1e-57	91.1
WP_087503526.1\|2436_3531_-	hypothetical protein	Q71T61	Escherichia_phage	1.3e-40	32.7
WP_087503525.1\|3520_4288_-	hypothetical protein	A0A222YXM9	Escherichia_phage	8.6e-135	98.4
WP_060877112.1\|4294_4957_-	DUF2829 domain-containing protein	A0A1B0VBT1	Salmonella_phage	5.0e-99	81.0
WP_000640903.1\|4971_5466_-	dUTP diphosphatase	A0A222YYP1	Escherichia_phage	8.1e-86	94.5
WP_087503524.1\|5462_5939_-	hypothetical protein	NA	NA	NA	NA
WP_087503523.1\|5935_6280_-	hypothetical protein	A0A222YYS6	Escherichia_phage	3.9e-55	94.7
WP_087503522.1\|6354_7383_-\|integrase	tyrosine-type recombinase/integrase	Q5XLQ5	Enterobacteria_phage	1.2e-59	41.9
WP_000888609.1\|8575_8815_+	hypothetical protein	Q5QBE5	Escherichia_phage	1.4e-06	96.4
WP_000897063.1\|8842_10351_-	hypothetical protein	Q5QBP2	Enterobacteria_phage	1.2e-161	56.8
WP_031325887.1\|10350_11331_-	hypothetical protein	NA	NA	NA	NA
WP_000435256.1\|11711_12104_-	hypothetical protein	NA	NA	NA	NA
WP_001130998.1\|12212_12398_-	hypothetical protein	Q5QBF3	Escherichia_phage	6.4e-28	98.4
WP_000488304.1\|12604_12796_-	hypothetical protein	A0A222YWJ0	Escherichia_phage	3.2e-30	100.0
WP_000579539.1\|13829_13994_-	DUF3927 family protein	A0A222YXW5	Escherichia_phage	1.8e-18	100.0
WP_000467090.1\|13993_14428_-	tellurite resistance TerB family protein	A0A222YXQ0	Escherichia_phage	3.7e-74	100.0
WP_024134673.1\|15243_15429_+	hypothetical protein	Q71T99	Escherichia_phage	1.5e-16	100.0
WP_000077919.1\|16787_17996_-	hypothetical protein	A0A222YW83	Escherichia_phage	4.5e-231	99.5
WP_050586432.1\|18109_18391_-	hypothetical protein	A0A222YW96	Escherichia_phage	3.2e-39	95.7
WP_001238268.1\|18405_18606_-	hypothetical protein	A0A222YWF9	Escherichia_phage	3.3e-30	98.5
WP_086252943.1\|18620_18917_-	VRR-NUC domain-containing protein	A0A222YXP1	Escherichia_phage	5.4e-53	100.0
WP_074470335.1\|19251_19512_-	hypothetical protein	A0A222YXI8	Escherichia_phage	3.1e-44	98.8
WP_074470334.1\|19514_19949_-	olxA	A0A222YZ35	Escherichia_phage	2.1e-74	93.8
WP_087503521.1\|19985_26822_-	DEAD/DEAH box helicase family protein	A0A222YYH3	Escherichia_phage	0.0e+00	98.9
WP_001273800.1\|26973_27459_+	TIGR02594 family protein	A0A222YWL8	Escherichia_phage	3.3e-92	100.0
WP_001344836.1\|27491_27689_-	hypothetical protein	A0A222YWF5	Escherichia_phage	3.1e-33	100.0
WP_052936018.1\|27688_28396_-	DNA-binding protein	A0A222YXY0	Escherichia_phage	1.1e-115	90.6
WP_000245715.1\|28395_28620_-	host cell division inhibitor Icd-like protein	A0A222YWB3	Escherichia_phage	8.8e-40	100.0
WP_087503520.1\|29034_29997_-	lytic replication protein	A0A222YXV1	Escherichia_phage	5.6e-176	98.8
WP_001191134.1\|30197_31196_-	hypothetical protein	A0A222YWA7	Escherichia_phage	1.9e-179	98.5
WP_071992514.1\|31209_32442_-\|portal	phage portal protein	A0A222YXQ7	Escherichia_phage	9.6e-237	100.0
WP_060877101.1\|32956_34342_-	hypothetical protein	A0A222YY44	Escherichia_phage	5.4e-236	96.7
WP_080028495.1\|34448_35657_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1B0VCD8	Salmonella_phage	8.6e-214	92.8
WP_060877123.1\|35773_36148_-	hypothetical protein	A0A222YWB0	Escherichia_phage	2.8e-38	93.5
WP_087503513.1\|36147_38085_-\|head	head protein	A0A222YWA3	Escherichia_phage	0.0e+00	98.3
WP_073714457.1\|38077_38698_-	hypothetical protein	A0A222YXB2	Escherichia_phage	8.1e-75	95.1
WP_000526264.1\|38687_39134_-	hypothetical protein	A0A222YXP5	Escherichia_phage	9.2e-81	100.0
WP_053919841.1\|39133_39460_-\|holin	holin	A0A222YZ46	Escherichia_phage	9.5e-51	99.1
WP_000904922.1\|39676_40249_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	4.6e-85	85.2
WP_087503512.1\|40308_40749_+\|tail	tail fiber protein	K7PH60	Enterobacterial_phage	3.5e-40	54.9
WP_032143395.1\|40759_41233_+\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	8.1e-35	52.4
WP_000072166.1\|41239_41854_-\|tail	tail assembly protein	Q9MCR5	Enterobacteria_phage	1.7e-61	61.5
WP_108161039.1\|41853_43740_-	hypothetical protein	A0A222YWB9	Escherichia_phage	6.4e-107	53.0
WP_001396839.1\|43742_43892_-	hypothetical protein	A0A222YXS1	Escherichia_phage	7.9e-21	98.0
WP_023908647.1\|44283_45129_-	hypothetical protein	A0A222YWB7	Escherichia_phage	3.0e-157	98.2
WP_023908648.1\|45139_46570_-	bleomycin hydrolase	A0A222YWB2	Escherichia_phage	2.2e-269	98.7
WP_087503511.1\|46566_46941_-	hypothetical protein	A0A222YXD0	Escherichia_phage	1.7e-64	97.6
WP_001025048.1\|51397_52219_-	hypothetical protein	A0A222YZ63	Escherichia_phage	8.5e-157	98.9
WP_001077897.1\|52607_53363_+	RepB family plasmid replication initiator protein	A0A222YYK1	Escherichia_phage	3.7e-138	100.0
WP_000021878.1\|53744_54452_-	hypothetical protein	A0A222YY05	Escherichia_phage	1.0e-126	100.0
WP_000187854.1\|54467_55019_-	hypothetical protein	A0A222YWE3	Escherichia_phage	1.3e-97	98.9
WP_000012433.1\|55073_55565_-	hypothetical protein	A0A222YWE4	Escherichia_phage	3.5e-89	100.0
WP_087503510.1\|55573_56146_-	hypothetical protein	A0A222YY02	Escherichia_phage	6.7e-100	98.9
WP_000801017.1\|56213_56948_-	hypothetical protein	A0A222YXT7	Escherichia_phage	5.9e-125	100.0
WP_087503509.1\|56991_58650_-\|tail	phage tail protein	A0A222YWC8	Escherichia_phage	1.4e-304	98.0
WP_087503508.1\|58717_58996_-	hypothetical protein	A0A222YWH8	Escherichia_phage	1.1e-39	96.7
WP_032342068.1\|59143_60841_-	hypothetical protein	A0A222YWC7	Escherichia_phage	0.0e+00	97.3
WP_032342084.1\|60999_61392_+	hypothetical protein	A0A222YXX4	Escherichia_phage	5.6e-66	97.7
WP_072650276.1\|61410_61869_+	hypothetical protein	A0A222YWJ4	Escherichia_phage	2.3e-87	98.7
WP_087503507.1\|62022_62481_-	hypothetical protein	A0A222YWG1	Escherichia_phage	4.7e-64	94.7
WP_087503506.1\|62551_63355_-	hypothetical protein	A0A222YXK1	Escherichia_phage	1.4e-100	84.0
WP_074417202.1\|63354_63639_-	alanine racemase	A0A222YXW1	Escherichia_phage	8.9e-37	81.9
WP_001217888.1\|63905_64862_+	recombinase	A0A222YXF2	Escherichia_phage	1.7e-180	99.7
64752:64766	attR	NA	NA	NA	NA
WP_052930744.1\|64874_65213_+	plasmid stabilization protein	A0A222YWJ6	Escherichia_phage	8.3e-50	96.4
WP_087503505.1\|65491_66133_+	AAA family ATPase	A0A222YXS3	Escherichia_phage	4.0e-109	93.0
WP_087503504.1\|66125_66410_+	hypothetical protein	A0A222YZA7	Escherichia_phage	5.6e-31	76.8
WP_087503503.1\|66554_67460_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A222YYM0	Escherichia_phage	5.9e-167	95.3
WP_000812238.1\|67452_68133_-	hypothetical protein	A0A222YXN3	Escherichia_phage	5.8e-135	100.0
WP_087503502.1\|68116_69022_-	recombination-associated protein RdgC	A0A222YY21	Escherichia_phage	3.9e-163	98.0
WP_087503501.1\|69081_69735_-\|plate	baseplate protein	A0A222YWF1	Escherichia_phage	1.3e-94	93.5
WP_069936439.1\|69731_70712_-\|tail	tail length tape measure protein	A0A222YXZ0	Escherichia_phage	9.5e-187	99.7
WP_000203293.1\|70715_71483_-	hypothetical protein	A0A222YWF4	Escherichia_phage	4.4e-139	100.0
WP_063074813.1\|71479_72271_-	hypothetical protein	A0A222YXU3	Escherichia_phage	2.8e-149	98.5
WP_000162415.1\|72433_72736_+	hypothetical protein	A0A222YWE2	Escherichia_phage	5.9e-55	100.0
WP_000806445.1\|72806_73145_+	HigA family addiction module antidote protein	A0A222YWD7	Escherichia_phage	1.3e-55	100.0
WP_001022420.1\|73201_73402_+	hypothetical protein	A0A222YXG1	Escherichia_phage	8.1e-29	90.8
WP_080077649.1\|73423_74152_+	hypothetical protein	A0A222YY57	Escherichia_phage	1.2e-72	58.3
WP_063074560.1\|74185_75379_-	hypothetical protein	A0A222YXT1	Escherichia_phage	1.3e-198	96.5
WP_000542383.1\|75371_75701_-	hypothetical protein	A0A222YYR0	Escherichia_phage	3.6e-58	100.0
WP_032323276.1\|75793_76075_-	HigA family addiction module antidote protein	I6ZVM3	Aeromonas_phage	1.3e-08	44.7
WP_032323275.1\|76083_76365_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2L1IV28	Escherichia_phage	7.5e-20	45.2
WP_000410954.1\|76701_77355_-	hypothetical protein	A0A222YZ79	Escherichia_phage	4.9e-115	99.5
WP_032323273.1\|77638_78247_+	hypothetical protein	NA	NA	NA	NA
WP_001396850.1\|78432_78660_+	hypothetical protein	NA	NA	NA	NA
WP_000717724.1\|78656_78968_-	hypothetical protein	A0A222YY28	Escherichia_phage	1.0e-33	83.0
WP_072275558.1\|79027_79954_-	Rha family transcriptional regulator	A0A222YWG0	Escherichia_phage	3.7e-148	84.3
WP_022630900.1\|79953_80169_-	host cell division inhibitor Icd-like protein	A0A222YWG3	Escherichia_phage	7.4e-36	98.6
WP_071526433.1\|80187_80307_-	hypothetical protein	NA	NA	NA	NA
WP_087503500.1\|80979_81558_-	recombinase	A0A222YXV2	Escherichia_phage	6.4e-74	96.9
WP_000240859.1\|81830_82454_+	DUF4406 domain-containing protein	A0A222YYT7	Escherichia_phage	5.8e-89	82.8
WP_050552930.1\|82483_82768_+	DNA-binding protein	A0A222YXX1	Escherichia_phage	5.2e-45	96.8
WP_087503499.1\|82757_83267_+	hypothetical protein	E7C9P6	Salmonella_phage	1.7e-38	66.0
WP_087503498.1\|83263_83905_+	hypothetical protein	A0A222YWM9	Escherichia_phage	8.6e-104	90.0
WP_023908606.1\|83901_84150_+	hypothetical protein	A0A1V0E5L1	Salmonella_phage	3.5e-29	84.8
WP_023908607.1\|84146_84440_+	DUF4752 family protein	A0A222YWQ2	Escherichia_phage	1.0e-35	86.5
WP_023908608.1\|84417_84642_+	hypothetical protein	A0A222YYR6	Escherichia_phage	2.5e-34	94.6
WP_001092152.1\|84638_84950_+	hypothetical protein	A0A222YY67	Escherichia_phage	1.8e-59	99.0
WP_108161038.1\|85061_86270_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	3.4e-210	94.0
WP_087503534.1\|86306_86975_+	serine/threonine protein phosphatase	A0A222YWF0	Escherichia_phage	8.6e-115	87.7
WP_087503533.1\|87071_88067_+	DUF968 domain-containing protein	A0A222YWL6	Escherichia_phage	6.2e-194	97.6
WP_108161037.1\|88080_88167_+	DUF4752 family protein	NA	NA	NA	NA
WP_060877081.1\|88163_88355_+	DUF1382 family protein	A0A0P0ZC60	Stx2-converting_phage	3.1e-17	81.4
WP_087503532.1\|88351_88972_+	ead/Ea22-like family protein	A0A222YY85	Escherichia_phage	2.6e-25	79.7
WP_047647121.1\|88968_89415_+	ead/Ea22-like family protein	A0A222YWN7	Escherichia_phage	7.4e-38	82.4
WP_000797279.1\|89760_89949_+	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	1.4e-30	98.4
WP_000951710.1\|89950_90160_+	hypothetical protein	A0A0F6TJE4	Escherichia_coli_O157_typing_phage	8.8e-34	94.2
WP_087503531.1\|90156_90846_+	DUF551 domain-containing protein	A0A2D1GLX9	Escherichia_phage	2.9e-113	89.9
WP_087503530.1\|90842_91103_+	eaa protein	A0A077SLR0	Escherichia_phage	8.4e-42	98.8
WP_063074823.1\|91388_91805_+	hypothetical protein	A0A076G6X8	Escherichia_phage	1.8e-25	61.2
WP_087503529.1\|91817_92111_+	hypothetical protein	A0A077SK23	Escherichia_phage	9.7e-47	93.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP022227

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1262 : 88640

Escherichia_phage(43.48%)

integrase,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001066953.1\|1262_2003_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	2.0e-24	57.6
WP_001309252.1\|2123_2312_-	hypothetical protein	NA	NA	NA	NA
WP_001072358.1\|2678_3848_+	hypothetical protein	NA	NA	NA	NA
WP_001322642.1\|4694_4967_-	transcriptional regulator	NA	NA	NA	NA
WP_001298664.1\|6209_8180_+	TonB-dependent hemoglobin/transferrin/lactoferrin family receptor	NA	NA	NA	NA
WP_000977394.1\|8186_8978_+	DUF4198 domain-containing protein	NA	NA	NA	NA
WP_001317493.1\|9716_10499_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	5.9e-139	99.6
WP_000255956.1\|10495_11518_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-199	99.1
WP_024193849.1\|12597_12972_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.8e-60	100.0
WP_001067855.1\|12996_13701_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000108589.1\|14327_14885_+	OsmC family protein	NA	NA	NA	NA
WP_000210409.1\|15026_15608_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000888080.1\|15612_15951_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_002431133.1\|15980_16310_-	thioredoxin family protein	V9SJ74	Achromobacter_phage	1.3e-10	34.7
WP_000039982.1\|16523_17630_+	alkene reductase	NA	NA	NA	NA
WP_087503554.1\|17695_18064_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|18009_18714_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_049802299.1\|19596_19860_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_000460651.1\|19852_20239_+	hypothetical protein	NA	NA	NA	NA
WP_001284954.1\|20246_20933_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001322387.1\|20910_21537_-	tetracycline resistance transcriptional repressor TetR(B)	NA	NA	NA	NA
WP_001089068.1\|21615_22821_+	tetracycline efflux MFS transporter Tet(B)	NA	NA	NA	NA
WP_001323225.1\|23811_23994_-	hypothetical protein	NA	NA	NA	NA
WP_000449408.1\|24015_24174_+	copper-sensitivity suppressor C	NA	NA	NA	NA
WP_000949452.1\|24163_24670_+	protein disulfide oxidoreductase	NA	NA	NA	NA
WP_012372823.1\|24852_25668_+	Na(+)-translocating NADH-quinone reductase subunit C	NA	NA	NA	NA
WP_071528361.1\|25826_26012_+	hypothetical protein	NA	NA	NA	NA
WP_000118029.1\|26014_27901_+	FTR1 family iron permease	NA	NA	NA	NA
WP_000178050.1\|27941_28469_+	iron transporter	NA	NA	NA	NA
WP_000119836.1\|28572_29952_+	DUF2318 domain-containing protein	NA	NA	NA	NA
WP_000964653.1\|29954_31238_+	ABC transporter permease	NA	NA	NA	NA
WP_000729219.1\|31227_32358_+	ABC transporter permease	NA	NA	NA	NA
WP_000117262.1\|32362_33058_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.5e-29	38.9
WP_001267176.1\|33044_33530_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_000874189.1\|33554_34040_+	hypothetical protein	NA	NA	NA	NA
WP_021546935.1\|35325_36330_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000734115.1\|36769_37522_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000090196.1\|37763_38636_+	DMT family transporter	NA	NA	NA	NA
WP_000872613.1\|38766_39990_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_032152933.1\|40175_40949_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_001067855.1\|41525_42230_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001336397.1\|42708_43065_-	hypothetical protein	NA	NA	NA	NA
WP_001137892.1\|43010_43595_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000004159.1\|43594_44833_-	MFS transporter	NA	NA	NA	NA
WP_000219391.1\|44829_45735_-	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_001067858.1\|45856_46561_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_077788461.1\|46537_46720_+	hypothetical protein	NA	NA	NA	NA
WP_004883563.1\|46901_47174_-	hypothetical protein	NA	NA	NA	NA
WP_001993321.1\|47192_47372_+	hypothetical protein	NA	NA	NA	NA
WP_000259031.1\|47301_48141_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|48134_48482_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000503573.1\|48687_49476_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5	NA	NA	NA	NA
WP_001389366.1\|49606_50080_-	trimethoprim-resistant dihydrofolate reductase DfrA17	A0A1B2IAU3	Erwinia_phage	1.3e-16	34.6
WP_000845048.1\|50237_51251_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_122997045.1\|51219_51744_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_001067858.1\|51780_52485_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000239590.1\|53762_54638_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
WP_001393253.1\|54684_55017_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
WP_001067855.1\|57338_58043_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_002063889.1\|59236_59779_-	AAA family ATPase	NA	NA	NA	NA
WP_000557452.1\|59791_60652_-	aminoglycoside N-acetyltransferase AAC(3)-IIa	NA	NA	NA	NA
WP_001067855.1\|60758_61463_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001334766.1\|62094_62925_-	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_063840321.1\|63055_63610_-	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
WP_001067855.1\|63753_64458_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000509966.1\|65059_65665_-	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
WP_001553819.1\|65759_68657_+\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	4.2e-182	37.8
WP_001398199.1\|68793_69195_-	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_000557619.1\|69127_69385_-	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_000616807.1\|69477_70131_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_071889078.1\|70320_70707_-	hypothetical protein	NA	NA	NA	NA
WP_032152935.1\|71069_71927_-	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_001365705.1\|71919_71994_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_072163418.1\|72077_72188_+	replication protein RepA	NA	NA	NA	NA
WP_000083821.1\|72228_72486_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_071529016.1\|72452_72704_+	hypothetical protein	NA	NA	NA	NA
WP_000156883.1\|72890_73913_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000005489.1\|74384_74738_+	hypothetical protein	NA	NA	NA	NA
WP_032152936.1\|75150_75729_-	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_059330006.1\|76567_76930_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	9.0e-34	88.5
WP_000624725.1\|76926_77277_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080227.1\|77307_77529_+	hypothetical protein	NA	NA	NA	NA
WP_001496175.1\|77885_78365_-	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_000514417.1\|78445_79849_-	YfcC family protein	NA	NA	NA	NA
WP_000154545.1\|79896_80901_-	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_000440183.1\|80985_81897_-	carbamate kinase	NA	NA	NA	NA
WP_000410951.1\|81907_83128_-	arginine deiminase	NA	NA	NA	NA
WP_032336874.1\|84887_84962_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_071586949.1\|85045_85162_+	replication protein RepA	NA	NA	NA	NA
WP_000083833.1\|85197_85455_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_001312851.1\|85738_85888_-	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_023149666.1\|85943_86186_+	hypothetical protein	NA	NA	NA	NA
WP_072142979.1\|86131_86365_-	hypothetical protein	NA	NA	NA	NA
WP_023149734.1\|87068_88640_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	4.9e-169	58.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP022226

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

11268 : 19383

Stx2-converting_phage(42.86%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148240171.1\|11268_11655_+\|transposase	transposase	B6DZU5	Stx2-converting_phage	1.7e-59	89.9
WP_032667561.1\|11651_11999_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	1.8e-60	96.5
WP_032667560.1\|12049_13588_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.8e-270	90.8
WP_005012528.1\|13698_14913_+	type II site-specific deoxyribonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
WP_032667557.1\|14946_16380_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	4.1e-106	51.5
WP_108082295.1\|16528_17225_+\|transposase	IS1 family transposase	A0A077SLN4	Escherichia_phage	1.5e-125	93.5
WP_123615964.1\|17379_18216_+	hypothetical protein	NA	NA	NA	NA
WP_053514996.1\|18459_19383_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	6.6e-174	98.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022229

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP022228

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP022227

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP022226

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection