CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP021756	Klebsiella pneumoniae strain AR_0113 plasmid unitig_5, complete sequence	0 crisprs	NA	0	2
NZ_CP021755	Klebsiella pneumoniae strain AR_0113 plasmid unitig_4, complete sequence	0 crisprs	RT	0	2
NZ_CP021752	Klebsiella pneumoniae strain AR_0113 plasmid unitig_1, complete sequence	0 crisprs	cas3,RT,csa3	0	9
NZ_CP021751	Klebsiella pneumoniae strain AR_0113 chromosome, complete genome	3 crisprs	cas3,DEDDh,WYL,RT,DinG,csa3	1	12
NZ_CP021753	Klebsiella pneumoniae strain AR_0113 plasmid unitig_2, complete sequence	1 crisprs	NA	2	2
NZ_CP021754	Klebsiella pneumoniae strain AR_0113 plasmid unitig_3, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 8178

Enterobacteria_phage(50.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071527925.1\|480_723_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000427623.1\|1020_2025_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_004152284.1\|2428_3439_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_004152286.1\|3899_4982_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	6.8e-186	96.4
WP_004152287.1\|5103_8178_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.7

DBSCAN-SWA_2

20199 : 20751

Wolbachia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152294.1\|20199_20751_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	1.1e-19	35.2

DBSCAN-SWA_3

25858 : 26584

Xanthomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152303.1\|25858_26584_-	type-F conjugative transfer system pilin acetylase TraX	A0A1D6ZIU7	Xanthomonas_phage	5.5e-06	29.4

DBSCAN-SWA_4

60736 : 64339

Cronobacter_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004178064.1\|60736_61558_-	DUF945 domain-containing protein	K4F5L3	Cronobacter_phage	2.6e-44	40.4
WP_004152722.1\|62391_62805_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004152721.1\|62805_63084_-	helix-turn-helix transcriptional regulator	O64356	Escherichia_phage	2.5e-07	39.4
WP_004152720.1\|63073_63394_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	6.8e-09	39.5
WP_004152719.1\|63474_63699_-	hypothetical protein	NA	NA	NA	NA
WP_004152718.1\|63709_63922_-	hypothetical protein	NA	NA	NA	NA
WP_004152717.1\|63982_64339_-	hypothetical protein	A0A248SL90	Klebsiella_phage	2.6e-25	58.1

DBSCAN-SWA_5

69759 : 74044

Emiliania_huxleyi_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004178066.1\|69759_71796_-	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	9.0e-22	26.0
WP_004152643.1\|71865_72114_-	DUF905 domain-containing protein	NA	NA	NA	NA
WP_004152644.1\|72162_72705_-	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	6.0e-50	76.7
WP_004152645.1\|73480_74044_-	methyltransferase	A8HNV9	Thalassomonas_phage	1.3e-18	34.1

DBSCAN-SWA_6

77181 : 166214

Escherichia_phage(15.62%)

transposase,protease,integrase

attL 73568:73584|attR 104629:104645

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
73568:73584	attL	NA	NA	NA	NA
WP_004152754.1\|77181_77436_-	hypothetical protein	H9C187	Pectobacterium_phage	1.2e-11	50.0
WP_004118478.1\|77672_78098_-	antirestriction protein	NA	NA	NA	NA
WP_004152753.1\|78618_78849_-	hypothetical protein	NA	NA	NA	NA
WP_004152765.1\|79082_80567_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004178083.1\|80972_81398_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.3e-31	49.6
WP_004152715.1\|81397_82669_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	5.6e-155	63.7
WP_004152062.1\|85620_86592_-	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	4.1e-150	86.6
WP_000523813.1\|86591_87758_-	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	1.4e-224	97.7
WP_004152063.1\|88509_89520_+	replication initiation protein	J9Q7H0	Salmonella_phage	8.8e-87	55.9
WP_001515717.1\|90236_90977_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
WP_004152065.1\|92120_93068_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	1.8e-12	30.6
WP_071527918.1\|93094_93406_-	EAL domain-containing protein	NA	NA	NA	NA
WP_004152067.1\|93470_94394_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	2.1e-175	98.4
WP_004197688.1\|95066_95324_-	hypothetical protein	NA	NA	NA	NA
WP_020444838.1\|95925_97380_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004152070.1\|98362_99640_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_004178088.1\|99702_101700_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	9.7e-21	25.9
WP_085955172.1\|102739_103947_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.7e-100	63.2
WP_004178091.1\|105375_105807_-	silver-binding protein SilE	NA	NA	NA	NA
104629:104645	attR	NA	NA	NA	NA
WP_003032875.1\|106057_107533_-	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_001572351.1\|107525_108206_-	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.1e-31	35.6
WP_000475512.1\|108395_109781_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_001246153.1\|109809_110163_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_004152079.1\|110276_111569_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_004098958.1\|111579_114726_+	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	S5VTK5	Leptospira_phage	4.0e-61	22.5
WP_000758228.1\|114812_115253_+	hypothetical protein	NA	NA	NA	NA
WP_004098955.1\|115379_117827_+	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	7.6e-84	35.8
WP_000843497.1\|117867_118065_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_004118669.1\|118098_118836_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4JAF5	uncultured_Caudovirales_phage	1.2e-11	32.5
WP_001023257.1\|119124_119574_-	copper resistance protein	NA	NA	NA	NA
WP_000925242.1\|119807_121625_+	multicopper oxidase PcoA	NA	NA	NA	NA
WP_001242438.1\|121624_122521_+	copper resistance outer membrane transporter PcoB	NA	NA	NA	NA
WP_000025662.1\|122560_122941_+	copper resistance system metallochaperone PcoC	NA	NA	NA	NA
WP_004118344.1\|122945_123875_+	copper resistance inner membrane protein PcoD	NA	NA	NA	NA
WP_001188930.1\|123929_124610_+	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4
WP_004152084.1\|124606_126007_+	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	4.1e-18	26.3
WP_004152085.1\|126223_126658_+	copper resistance system metallochaperone PcoE	NA	NA	NA	NA
WP_004152086.1\|126889_127069_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_031944101.1\|128811_129321_+	major intrinsic protein MIP	NA	NA	NA	NA
WP_004152091.1\|129370_129868_-	N-acetyltransferase	NA	NA	NA	NA
WP_004152092.1\|130199_130526_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085903505.1\|130525_131236_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	2.9e-92	77.0
WP_004182005.1\|131244_131790_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004152095.1\|131865_132228_+	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
WP_004152096.1\|134124_134661_+	N-acetyltransferase	NA	NA	NA	NA
WP_004152097.1\|134693_135119_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.3e-52	72.9
WP_004152098.1\|135131_136421_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4J144	uncultured_Caudovirales_phage	1.9e-171	74.0
WP_004152099.1\|136468_138220_-	arsenite efflux transporter ATPase subunit ArsA	NA	NA	NA	NA
WP_004152100.1\|138237_138600_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_004152101.1\|138649_139000_-	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	1.4e-23	50.9
WP_004152102.1\|139357_139627_+	hypothetical protein	NA	NA	NA	NA
WP_004152103.1\|139614_140190_+	hypothetical protein	NA	NA	NA	NA
WP_004152104.1\|140220_140715_+	DNA-binding protein	NA	NA	NA	NA
WP_004152105.1\|140758_141127_+	hypothetical protein	NA	NA	NA	NA
WP_004152106.1\|141160_141364_+	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_004152107.1\|141412_141670_+	hypothetical protein	NA	NA	NA	NA
WP_004152108.1\|141745_142000_+	hypothetical protein	NA	NA	NA	NA
WP_003026799.1\|142175_142442_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_003026803.1\|142429_142912_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020314316.1\|143123_144470_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_004152113.1\|146312_147275_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_009483782.1\|147261_148011_-	diguanylate cyclase	NA	NA	NA	NA
WP_004152115.1\|148248_148446_-	hypothetical protein	NA	NA	NA	NA
WP_004152116.1\|148445_151241_-	heat shock survival AAA family ATPase ClpK	K4FB40	Cronobacter_phage	5.2e-129	41.0
WP_004152117.1\|151355_151925_-	small heat shock protein sHSP20	NA	NA	NA	NA
WP_004152118.1\|151959_152241_-	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	5.2e-05	38.2
WP_004118208.1\|152484_152748_-	hypothetical protein	NA	NA	NA	NA
WP_004118209.1\|152762_153026_+\|transposase	transposase	NA	NA	NA	NA
WP_000019473.1\|154227_155208_+\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_004152692.1\|156416_157286_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004152693.1\|157279_158290_-	phosphonate dehydrogenase PtxD	A0A1V0SBV6	Catovirus	1.4e-15	25.1
WP_004152694.1\|158298_159126_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_004152695.1\|159134_159998_-	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004153729.1\|159994_160822_-	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-20	37.6
WP_001067855.1\|161677_162382_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_044117068.1\|163685_164354_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.9e-130	99.5
WP_000018329.1\|164543_165359_-	aminoglycoside O-phosphotransferase APH(3')-Ia	A0A193DTG4	Autographa_californica_nuclear_polyhedrosis_virus	6.1e-163	100.0
WP_001067855.1\|165509_166214_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

DBSCAN-SWA_7

169552 : 188554

Escherichia_phage(18.18%)

transposase,integrase

attL 162862:162876|attR 180203:180217

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
162862:162876	attL	NA	NA	NA	NA
WP_001389365.1\|169552_170317_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_000130000.1\|170543_170849_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000184001.1\|170859_172065_-	chromate efflux transporter	NA	NA	NA	NA
WP_000376616.1\|172220_172424_-	hypothetical protein	NA	NA	NA	NA
WP_000259031.1\|172551_173391_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|173384_173732_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001206356.1\|173895_174687_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_001336345.1\|174692_174983_-	DUF1010 domain-containing protein	NA	NA	NA	NA
WP_001083725.1\|175094_175592_-	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
WP_000845039.1\|175736_176750_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_000454193.1\|176952_177303_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_000147567.1\|177428_177989_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	4.0e-49	86.2
WP_001138064.1\|177991_180958_+\|transposase	Tn3-like element TnAs3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.6
180203:180217	attR	NA	NA	NA	NA
WP_000656305.1\|181024_181402_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000412211.1\|181602_182262_-	type A-1 chloramphenicol O-acetyltransferase	G3CFL0	Escherichia_phage	8.4e-131	100.0
WP_000333416.1\|183878_184151_+	His-Xaa-Ser system protein HxsD	NA	NA	NA	NA
WP_004118216.1\|184150_185539_+	His-Xaa-Ser system radical SAM maturase HxsB	S5VT21	Leptospira_phage	6.3e-51	29.0
WP_000005560.1\|185531_186644_+	His-Xaa-Ser system radical SAM maturase HxsC	S5WIP3	Leptospira_phage	1.5e-47	33.8
WP_004118217.1\|186640_187276_+	His-Xaa-Ser repeat protein HxsA	NA	NA	NA	NA
WP_004114613.1\|187832_188210_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.6e-57	91.3
WP_004152557.1\|188206_188554_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.0e-59	95.7

DBSCAN-SWA_8

192376 : 195065

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004118832.1\|192376_194110_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.9e-15	29.6
WP_004118225.1\|194117_195065_-	acetamidase/formamidase family protein	A0A1V0S8X7	Catovirus	9.6e-11	22.7

DBSCAN-SWA_9

208540 : 209308

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152282.1\|208540_209308_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	9.8e-14	25.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP021751

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021751_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021751_1

739804-739889

Orphan

Consensus_repeat	Method
AATAAAAACCATAAAAACCACAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021751_1

>merge|NZ_CP021751|1|739804-739889|CRISPRCasFinder
AATAAAAACCATAAAAACCACAGTCATAAATCAGAGATATATCACTCCCGGGCAGTTCAGCGAATAAAAACCATAAAAACCATAGT

>NZ_CP021751|1|1|739804-739889|CRISPRCasFinder
AATAAAAACCATAAAAACCACAGT	CATAAATCAGAGATATATCACTCCCGGGCAGTTCAGCG
AATAAAAACCATAAAAACCATAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021751.1\|WP_002888345.1\|739986_741351_+\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP021751.1\|WP_002888321.1\|729509_730358_-\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP021751.1\|WP_002888332.1\|736488_737316_+\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP021751.1\|WP_002888323.1\|730362_730740_-\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP021751.1\|WP_002888370.1\|752836_753682_+\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP021751.1\|WP_002888320.1\|728774_729254_+\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP021751.1\|WP_002888353.1\|748443_749139_-\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP021751.1\|WP_002888340.1\|738036_739662_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP021751.1\|WP_002888368.1\|750789_752499_-\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP021751.1\|WP_004151368.1\|742816_745723_-\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP021751.1\|WP_002888347.1\|741530_742070_+\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP021751.1\|WP_002888329.1\|732555_733842_-\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP021751.1\|WP_002888327.1\|731560_732550_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP021751.1\|WP_002888348.1\|742144_742804_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP021751.1\|WP_002888373.1\|753810_754578_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP021751.1\|WP_002888324.1\|730742_731564_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP021751.1\|WP_002888349.1\|745910_748268_-\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP021751.1\|WP_002888337.1\|737348_738047_-\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP021751.1\|WP_002888357.1\|749276_750779_-\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP021751.1\|WP_004147026.1\|733896_736245_-\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158

Protein	Function_ID	Function_description	E-value
NZ_CP021751.1\|WP_002888345.1\|739986_741351_+\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
NZ_CP021751.1\|WP_002888321.1\|729509_730358_-\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP021751.1\|WP_002888332.1\|736488_737316_+\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
NZ_CP021751.1\|WP_002888323.1\|730362_730740_-\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
NZ_CP021751.1\|WP_002888370.1\|752836_753682_+\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP021751.1\|WP_002888320.1\|728774_729254_+\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
NZ_CP021751.1\|WP_002888353.1\|748443_749139_-\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP021751.1\|WP_002888340.1\|738036_739662_-\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	6.55037e-173
NZ_CP021751.1\|WP_002888368.1\|750789_752499_-\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP021751.1\|WP_004151368.1\|742816_745723_-\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP021751.1\|WP_002888347.1\|741530_742070_+\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
NZ_CP021751.1\|WP_002888329.1\|732555_733842_-\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP021751.1\|WP_002888327.1\|731560_732550_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP021751.1\|WP_002888348.1\|742144_742804_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
NZ_CP021751.1\|WP_002888373.1\|753810_754578_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP021751.1\|WP_002888324.1\|730742_731564_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
NZ_CP021751.1\|WP_002888349.1\|745910_748268_-\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP021751.1\|WP_002888337.1\|737348_738047_-\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	5.03078e-66
NZ_CP021751.1\|WP_002888357.1\|749276_750779_-\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP021751.1\|WP_004147026.1\|733896_736245_-\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0

>NZ_CP021751.1|WP_002888340.1|738036_739662_-|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEAHDAS
>NZ_CP021751.1|WP_002888337.1|737348_738047_-|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSDREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP021751.1|WP_002888332.1|736488_737316_+|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP021751.1|WP_004147026.1|733896_736245_-|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP021751.1|WP_002888329.1|732555_733842_-|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP021751.1|WP_002888327.1|731560_732550_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP021751.1|WP_002888324.1|730742_731564_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP021751.1|WP_002888323.1|730362_730740_-|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP021751.1|WP_002888321.1|729509_730358_-|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP021751.1|WP_002888320.1|728774_729254_+|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR
>NZ_CP021751.1|WP_002888345.1|739986_741351_+|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP021751.1|WP_002888347.1|741530_742070_+|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>NZ_CP021751.1|WP_002888348.1|742144_742804_-|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP021751.1|WP_004151368.1|742816_745723_-|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESIDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAGIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP021751.1|WP_002888349.1|745910_748268_-|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLIEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSHVNAWWAQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP021751.1|WP_002888353.1|748443_749139_-|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP021751.1|WP_002888357.1|749276_750779_-|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATVEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP021751.1|WP_002888368.1|750789_752499_-|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSKAALTH
>NZ_CP021751.1|WP_002888370.1|752836_753682_+|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVREACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP021751.1|WP_002888373.1|753810_754578_+|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR

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Crispr_ID: NZ_CP021751_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021751_2

1223775-1223870

Orphan

Consensus_repeat	Method
TTGTGCCAACAGAATGCCAACAAAGTGCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021751_2

>merge|NZ_CP021751|2|1223775-1223870|CRISPRCasFinder
TTGTGCCAACAGAATGCCAACAAAGTGCCAACGCAAACCCAGTAACCACGCTGCGTACCGGCGAGGTTGTGCCAACAGAATGCCAACAAAGTGCCA

>NZ_CP021751|2|2|1223775-1223870|CRISPRCasFinder
TTGTGCCAACAGAATGCCAACAAAGTGCCA	ACGCAAACCCAGTAACCACGCTGCGTACCGGCGAGG
TTGTGCCAACAGAATGCCAACAAAGTGCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021751.1\|WP_004151306.1\|1219072_1219753_-\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NZ_CP021751.1\|WP_004151294.1\|1225989_1226496_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021751.1\|WP_004151300.1\|1221843_1222533_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP021751.1\|WP_004151286.1\|1229383_1230019_+\|protein-ninG	unknown	unknown	gnl\|CDD\|368603
NZ_CP021751.1\|WP_004151293.1\|1226602_1227445_+\|translation-repressor-RelE	unknown	unknown	gnl\|CDD\|379401
NZ_CP021751.1\|WP_004151284.1\|1230145_1230676_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|379158
NZ_CP021751.1\|WP_004151296.1\|1224269_1225700_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672
NZ_CP021751.1\|WP_004151287.1\|1229220_1229391_+\|NinE-family-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP021751.1\|WP_004151310.1\|1218264_1218921_-\|DNA-methyltransferase	unknown	unknown	gnl\|CDD\|227069
NZ_CP021751.1\|WP_004151295.1\|1225699_1225993_+\|protein-ren	unknown	unknown	gnl\|CDD\|238042
NZ_CP021751.1\|WP_004151303.1\|1220983_1221178_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021751.1\|WP_004151285.1\|1230015_1230153_+\|YlcG-family-protein	unknown	unknown	unknown
NZ_CP021751.1\|WP_004151304.1\|1220610_1220895_-\|host-nuclease-inhibitor-GamL	unknown	unknown	unknown
NZ_CP021751.1\|WP_004151301.1\|1221277_1221493_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021751.1\|WP_004151288.1\|1228765_1229221_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182057
NZ_CP021751.1\|WP_004151308.1\|1218917_1219076_-\|DUF1317-family-protein	unknown	unknown	gnl\|CDD\|284449
NZ_CP021751.1\|WP_001548453.1\|1222934_1223156_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|336083
NZ_CP021751.1\|WP_004151299.1\|1222660_1222894_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NZ_CP021751.1\|WP_004151305.1\|1219749_1220595_-\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871
NZ_CP021751.1\|WP_004151291.1\|1227617_1228265_+\|DUF551-domain-containing-protein	unknown	unknown	gnl\|CDD\|367946

Protein	Function_ID	Function_description	E-value
NZ_CP021751.1\|WP_004151306.1\|1219072_1219753_-\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	1.68114e-32
NZ_CP021751.1\|WP_004151286.1\|1229383_1230019_+\|protein-ninG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	9.44908e-60
NZ_CP021751.1\|WP_004151300.1\|1221843_1222533_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	1.58097e-27
NZ_CP021751.1\|WP_004151293.1\|1226602_1227445_+\|translation-repressor-RelE	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	0.000117969
NZ_CP021751.1\|WP_004151284.1\|1230145_1230676_+\|HNH-endonuclease	gnl\|CDD\|379158	pfam13392, HNH_3, HNH endonuclease. This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.	8.84074e-15
NZ_CP021751.1\|WP_004151296.1\|1224269_1225700_+\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	7.87266e-159
NZ_CP021751.1\|WP_004151287.1\|1229220_1229391_+\|NinE-family-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	1.47696e-19
NZ_CP021751.1\|WP_004151310.1\|1218264_1218921_-\|DNA-methyltransferase	gnl\|CDD\|227069	COG4725, IME4, Transcriptional activator, adenine-specific DNA methyltransferase [Signal transduction mechanisms / Transcription].	6.42213e-22
NZ_CP021751.1\|WP_004151295.1\|1225699_1225993_+\|protein-ren	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	0.000668668
NZ_CP021751.1\|WP_004151288.1\|1228765_1229221_+\|hypothetical-protein	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	1.50704e-78
NZ_CP021751.1\|WP_004151308.1\|1218917_1219076_-\|DUF1317-family-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	3.35548e-20
NZ_CP021751.1\|WP_001548453.1\|1222934_1223156_+\|hypothetical-protein	gnl\|CDD\|336083	pfam05269, Phage_CII, Bacteriophage CII protein. This family consists of several phage CII regulatory proteins. CII plays a key role in the lysis-lysogeny decision in bacteriophage lambda and related phages.	1.55058e-09
NZ_CP021751.1\|WP_004151299.1\|1222660_1222894_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	9.32854e-22
NZ_CP021751.1\|WP_004151305.1\|1219749_1220595_-\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	3.75286e-34
NZ_CP021751.1\|WP_004151291.1\|1227617_1228265_+\|DUF551-domain-containing-protein	gnl\|CDD\|367946	pfam04448, DUF551, Protein of unknown function (DUF551). This family represents the carboxy terminus of a protein of unknown function, found in dsDNA viruses with no RNA stage, including bacteriophages lambda and P22, and also in some Escherichia coli prophages.	8.71432e-11

>NZ_CP021751.1|WP_001548453.1|1222934_1223156_+|hypothetical-protein
MESSTTRNKVEARRIESWLHSQIAELGTTNIAKVAGVNKSTVSRWRESLLPNMSLLLAILISNRPGEKGDFEA
>NZ_CP021751.1|WP_004151299.1|1222660_1222894_+|helix-turn-helix-domain-containing-protein
MKNPAVEKAISIAGSQKELAKRCGKAQSTICDWLNGKKRISPVHVPDLVAAVNGEIKAYEFRPDLPSIFPPPNNSAA
>NZ_CP021751.1|WP_004151300.1|1221843_1222533_-|helix-turn-helix-transcriptional-regulator
MDFSERLARAMSLAGYTQGRLAKEVGMAQSSVNKLLNGANGSRKTVEIASVLGVRPEWLSTGAGEMLADSIQITQMQTPVTPQNGIYRVDVLDVKASAGPGALITNDFIETIRAIEYTSEQARSLFGNRPAHHIKVITVTGDSMDTTISPGDEIFVDISSTHFDSDGVYVFVFGKTLHVKRLQMQRDRLAVISDNPIYEKWYVEPGDEDQFYVMARVLLRQSIEYKRFA
>NZ_CP021751.1|WP_004151301.1|1221277_1221493_-|hypothetical-protein
MSKENNGGPAYPTQGYEGLTVRDYFAAKAMQGWLAGYPAGINHPARSEEGFTVAELSYLMADAMLKAREEV
>NZ_CP021751.1|WP_004151303.1|1220983_1221178_-|hypothetical-protein
MANSIPNNGRAVMMRNRRTGAAWLVSFDYRDGSYWHEPQGNLRHIRRPYASRSIEPNLVPAGTH
>NZ_CP021751.1|WP_004151304.1|1220610_1220895_-|host-nuclease-inhibitor-GamL
MNAYRAYDVIEERKWAEQTLTEEKQKWIEDRAKEVFDSLPEDPYAALRQSVSSKSFPYEGLRSDKAGEVYNDLRTAIAYAQAEYDWDHRTGCPF
>NZ_CP021751.1|WP_004151305.1|1219749_1220595_-|phage-recombination-protein-Bet
MANELVITASSLAERGIDGATWSALKNSIYPGAKDESVMMALDYCRARNLDPLLKPVHLVPMSVKDSKSGKSEWRDVVMPGIGLYRIQADRSGDYAGAKEPEFGPDVTLTLTGIEVTVPQWCKYTVSKRMPSGEIVEFSAKEYWVENYATAGRDTTAPNAMWKKRPYGQLAKCAEAQALRKAWPEIGQQPTAEEMEGKTLEVDARDVTPRSTPEAPPLVASEETLQAITDLLTSLNKDWEQDFLPLCSNIFKRDIFQASQLTEEEAQKGFSFLQKKAQVAA
>NZ_CP021751.1|WP_004151306.1|1219072_1219753_-|YqaJ-viral-recombinase-family-protein
MTPEIILERTGIDVTRVEQGDESWHRLRLGVITASEVHNVISKPKSGKKWTDMKMSYFLTLLAEVCTGVAPEVNAKALAWGKQYEADARTLFEFTTDVKVTESPILFRDEGMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQFSMWVTGKDAWYFANYDPRMKREGIHHVVVERDDKYMSDFNEMVPEFISKMDESLAEIGFTFGEQWK
>NZ_CP021751.1|WP_004151308.1|1218917_1219076_-|DUF1317-family-protein
MKHYRDAITVGKVKCMYSVLHRGWLMPSGEVVRNPLKAQRLAEELDTKRGAR
>NZ_CP021751.1|WP_004151310.1|1218264_1218921_-|DNA-methyltransferase
MKRYSLIYADPAWSYGNTISNGAAVDHYPTMSLLDMKRLPVWELAADNAVLAMWYTGTHNQEAIELAEAWGFTVRTMKGFTWVKLNQLAELRITKALAEGDVTDFYDFLALLNAETRMNGGNHTRANTEDVLIATRGAGLERKHAGIKQVVYSPLGAHSEKPWEVRHRLELLYGDVPRIELFSRSAAPGWSHWGNQCATASVELIPGCAIDVVKTEAA
>NZ_CP021751.1|WP_004151296.1|1224269_1225700_+|AAA-family-ATPase
MTSDFMTPPHSIEAEQSVLGGLLLDDDNSERTQKVLSILKPESFYARPHQVIFAEMRQMYRDHKPVDLLTLFDALESKGLTETVGGFAYLAEMSKNTPSAANIVAYAMRVRETAMERYGIEKTTKAIELLYARNGMTAEQKFDAIQGLFTEITEHVKTGRRTGLRTFYDAVTDWSAEFDERLKPDGRSRGLSTGIRSLDELLGVKRIVRGSLFVIGARPKMGKTTLYTQMGINCATVENEPALMFSLEMPEGQMVEKITAQKGRISPNLFYPDMTKDDYGYRGDWNSDLQKATGVMGALIETNNLLIDDTPGISLAHVMAESRRIKRERGKVGMILVDYLTLMTADKAERNDLAYGLITKGLKILAKELDCVVVLLTQLNRDLEKRTNKRPLPSDSRDTGQIEQDCDYWLAIYREGAYDENANQSDTELLLRLNRHGETGVVYCEQRHGAIYDCDQEAASQRRREKEQKPTKRGGF
>NZ_CP021751.1|WP_004151295.1|1225699_1225993_+|protein-ren
MTGKDAILNYLKTHKTCSSPDVAAASGMTHTCINQAANILAKQGVLVAEARVWRTVYYRLATEEEIAGRKSTNQIFNECRQSPAMKRVLAVYGRTSA
>NZ_CP021751.1|WP_004151294.1|1225989_1226496_+|hypothetical-protein
MTITLQAVNKLIASMESAGELSIREQKFLKLAKEFRICSASLDAAIKTGNMLADQNAQLAAENVALKDINAWCKTDAFKNMYREFKTAEALGCSDADCMHDAMLVAIMHAPATPATDRIVAGIKADGVEEFAAKLRIPGDDQFFDALAKGIALAADDFAKQLREGADK
>NZ_CP021751.1|WP_004151293.1|1226602_1227445_+|translation-repressor-RelE
MTDITELAQSLKAAAEKASNGDWVKESGDGWEACCSANDQANGGFIIAHFVGPDAAENCEFVQAANPANVLALVEALEYYKSREERVTSLVRDNSKSWDELYRQVEAKGKRNVELVEALESEKRICATWRKTAESTSEKLEKAQAAERRWHRVASRVHEQACESDVKIDELEAIRAAAEKLVRCKGRYHSEQNYRALAALFGVNTPDLPPLEHENVHYADAAEMEIEALRQRIAELESRTVKLPPRVDSSNVPFAGNAWNCCLDEVEKRLTAAGIKMEAE
>NZ_CP021751.1|WP_004151291.1|1227617_1228265_+|DUF551-domain-containing-protein
MTNNQLAENSVIQLLNSVKLARDNAELADNRVDHSFYYALTIALEELQERRKAAMDSEPVLWAWHHLDMWHVTSHDGRARDLWLSGFKVIPLYRHAQPVLVIPDEMTAEQAYEIGYYYGDPVDVFARGANWMRQHIIDSTLAAAPQSPGSDPATVPGKWISVSERMPENDGAYLCWDNRYVTTYAFIFGAWQANQFIAKNITHWMPLPAGPQEVR
>NZ_CP021751.1|WP_004151288.1|1228765_1229221_+|hypothetical-protein
MNIPQCGIKLHNGNFSAIGKILQEQLSDGKCLRLQVKEWREKRSLSQNALSHMWYAEISEYLINSGRTDATPEWVKRNLKKTYLGCEEVTYTDFITGEKTTTWEPRHTSDLDTGEMHIFLTKVEAWCAQFGLALTIPHGCEYQQLQQKQEA
>NZ_CP021751.1|WP_004151287.1|1229220_1229391_+|NinE-family-protein
MSSLLAKVIERGIFRVPARRKRKVEDKPSDIPTLKDYTARLVDKKWLRLRARRPHA
>NZ_CP021751.1|WP_004151286.1|1229383_1230019_+|protein-ninG
MRKPARRKCAHCREWFHPAREGQVVCSFECASAIGKKQTAKAREAAKARAVKRQRESEKEGRQRRKARLAELRPNGYYKAQAQKAFNAYIRARDAALPCISCGETNPPDLHGGQWDCGHFKTVGAYPELRFEERNAHKQCKSCNAGAGKYTAKELTVAQQYEAGLVARYGQEYVDWLNGPHEMTNYRREDFIRIRDEYRAKLKALKQREAA
>NZ_CP021751.1|WP_004151285.1|1230015_1230153_+|YlcG-family-protein
MNHDIIERIRDRWKKLRLLRSRGTVLVDYLILRNFIASLSRGSYE
>NZ_CP021751.1|WP_004151284.1|1230145_1230676_+|HNH-endonuclease
MSKSEKSITQELLRTLLEYDPQTGIFRWKIKASSSAHPGDIAGCIDGQGYRVIRIYGKNRKAHRLAWLYVYGDEPEVIDHIDRNRSNNAIENLRAVTFSQNSANRAAKSKNKSGFTGVYWNELGKKWQASIVANGRTHYVGLFATAQEAAKARTEYARQLYANFYIPSFHDQEAAK

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Crispr_ID: NZ_CP021751_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021751_3

1609561-1609638

Orphan

Consensus_repeat	Method
AAGGCGTCAGCCGCCGCCCGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021751_3

>merge|NZ_CP021751|3|1609561-1609638|CRISPRCasFinder
AAGGCGTCAGCCGCCGCCCGGCAAAATAACCGCGCAATAGCACCGTAGGCCGGGCAAGGCGTCAGCCGCCGCCCGGCA

>NZ_CP021751|3|3|1609561-1609638|CRISPRCasFinder
AAGGCGTCAGCCGCCGCCCGGCA	AAATAACCGCGCAATAGCACCGTAGGCCGGGC
AAGGCGTCAGCCGCCGCCCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021751.1\|WP_004151699.1\|1604319_1606008_+\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448
NZ_CP021751.1\|WP_002895284.1\|1598060_1598984_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|225813
NZ_CP021751.1\|WP_002895358.1\|1603451_1604177_+\|histidine-utilization-repressor	unknown	unknown	gnl\|CDD\|184961
NZ_CP021751.1\|WP_004142100.1\|1614018_1614774_+\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340
NZ_CP021751.1\|WP_004151700.1\|1612877_1614035_+\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_CP021751.1\|WP_002895578.1\|1610337_1611627_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189
NZ_CP021751.1\|WP_002895280.1\|1596589_1596802_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|313818
NZ_CP021751.1\|WP_002895648.1\|1614766_1615489_+\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
NZ_CP021751.1\|WP_004151696.1\|1599679_1600963_-\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP021751.1\|WP_002895580.1\|1611840_1612881_+\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|185063
NZ_CP021751.1\|WP_002895655.1\|1616863_1618885_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_CP021751.1\|WP_004151701.1\|1619062_1619155_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021751.1\|WP_002895652.1\|1616239_1616452_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021751.1\|WP_004151698.1\|1602433_1603390_+\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|234974
NZ_CP021751.1\|WP_004152853.1\|1615430_1616153_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223487
NZ_CP021751.1\|WP_002895420.1\|1606004_1607531_+\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484
NZ_CP021751.1\|WP_002895283.1\|1597537_1598044_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021751.1\|WP_004151697.1\|1601219_1602437_+\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
NZ_CP021751.1\|WP_002895575.1\|1609790_1610267_-\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
NZ_CP021751.1\|WP_004147672.1\|1607629_1609012_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182566

Protein	Function_ID	Function_description	E-value
NZ_CP021751.1\|WP_004151699.1\|1604319_1606008_+\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
NZ_CP021751.1\|WP_002895284.1\|1598060_1598984_-\|acyltransferase-family-protein	gnl\|CDD\|225813	COG3274, COG3274, Predicted O-acyltransferase [General function prediction only].	6.63632e-09
NZ_CP021751.1\|WP_002895358.1\|1603451_1604177_+\|histidine-utilization-repressor	gnl\|CDD\|184961	PRK14999, PRK14999, histidine utilization repressor; Provisional.	3.37417e-172
NZ_CP021751.1\|WP_004142100.1\|1614018_1614774_+\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	1.7976e-160
NZ_CP021751.1\|WP_004151700.1\|1612877_1614035_+\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
NZ_CP021751.1\|WP_002895280.1\|1596589_1596802_-\|hypothetical-protein	gnl\|CDD\|313818	pfam10684, BDM, Putative biofilm-dependent modulation protein. This is a family of tightly conserved proteins from Enterobacteriaceae which are annotated as being biofilm-dependent modulation protein homologs.	0.00154989
NZ_CP021751.1\|WP_002895648.1\|1614766_1615489_+\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	4.52132e-105
NZ_CP021751.1\|WP_002895578.1\|1610337_1611627_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
NZ_CP021751.1\|WP_002895580.1\|1611840_1612881_+\|biotin-synthase-BioB	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
NZ_CP021751.1\|WP_004151696.1\|1599679_1600963_-\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP021751.1\|WP_002895655.1\|1616863_1618885_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP021751.1\|WP_004151698.1\|1602433_1603390_+\|formimidoylglutamase	gnl\|CDD\|234974	PRK01722, PRK01722, formimidoylglutamase; Provisional.	8.10638e-178
NZ_CP021751.1\|WP_004152853.1\|1615430_1616153_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223487	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	3.17026e-74
NZ_CP021751.1\|WP_002895420.1\|1606004_1607531_+\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NZ_CP021751.1\|WP_004151697.1\|1601219_1602437_+\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
NZ_CP021751.1\|WP_002895575.1\|1609790_1610267_-\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	7.58373e-117
NZ_CP021751.1\|WP_004147672.1\|1607629_1609012_+\|amino-acid-permease	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0

>NZ_CP021751.1|WP_004147672.1|1607629_1609012_+|amino-acid-permease
MQQQHKPHLLRGLNARHIRFIALGSAIGTGLFYGSASAIKAAGPAVLLAYLIGGAAVFIVMRALGEMAVRNPVSGSFGSYARQYLGPLAGFITGWTYTFEMVIVALADVTAFGIYMGLWYPDVPRWIWILSIIFFIGAMNLCNVRVFGEMEFWLSLVKVVAIIAMMLAGAGIIFFGFGHSFPATGLENLWSHGGFAPNGWQGVIASLGIVMFAFGGVEIIGVTAAEAKDPKKVIPQAINTIPLRIILFYVCTLAVLMAIFPWNSFGEQGSPFVLIFDGLGIPAAATILNIIVISASISAINSDIFGAGRMMYGMSKEGLAPKSFQRIASNGVPWMTVVVMGGALLAAVVLNYLIPEQVFVLIASLAAFATVWVWLMILLSHFAMRRGLSAEERSQIAFPIPFWPVAPLLTLLFMGLVIAVLGMFAETRMALIAGLVWLGLLTVVWYARVRKTALQVATEQ
>NZ_CP021751.1|WP_002895420.1|1606004_1607531_+|histidine-ammonia-lyase
MKSLTLIPGQLSLSQLRDVYSHPVNITLDSGAFAAIDESVACVNAILAEGRTAYGINTGFGLLAQTRISTEDLENLQRSLVLSHAAGVGEPLDDDLTRLIMVLKINSLSRGFSGIRLSVIQALIGLVNAGVTPWIPAKGSVGASGDLAPLAHMSLTLLGEGKARVRGGEWLPATEALRQVGLEPITLAAKEGLALLNGTQASTAFALRGLFEAEDLFASAVVCGALTTEAALGSRRPFDARIHEVRGQRGQIDAAALYRHLLTDDSAISQSHHNCSKVQDPYSLRCQPQVMGACLTQIRQAAEVLLAEANAVSDNPLVFAAENDVISGGNFHAEPVAMAADNIALAIAEIGSLSERRIALMMDSHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGRRLWAMAENTRGVLAVEWLAAAQGLDMREGLTTSPLLEEARHLLRERVPHYTQDRYFAPDIDNAIALLAARHLTRLLPAVLH
>NZ_CP021751.1|WP_004151699.1|1604319_1606008_+|urocanate-hydratase
MSQSKYRQLDVRAPRGTTLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVKALKNLESDETLLVQSGKPVGVFKTHENSPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYQGSLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLRTRYVDEQATSLDDALARIKKYTAEGRAISIALCGNAAEIVPELVKRGVRPDMVTDQTSAHDPLHGYLPKGWSWEEYQQKAESDPQGTILAAKRSMADHVQAMLAFHEMGVPTFDYGNNIRQMAQEVGVSNAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIIKDDQHLHHWLDMARERISFQGLPARICWVGLEWRQKLGLAFNEMVRSGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAARIARVLHNDPATGVMRHADAGYEIAIECAAEQGLNLPMVAATQGNAK
>NZ_CP021751.1|WP_002895358.1|1603451_1604177_+|histidine-utilization-repressor
MFAQQPRSAPAPFYEKVKQAISEKIHSGVWRPHDRIPSEAELVAQFGFSRMTINRALRELTDEGLLVRLQGVGTFVAEPKGQSALFEVRSIAAEIVARHHQHRCEVLLLEETRADHIQATALSVPEGTRIFHSLMVHYENEVPVQIEDRCVNAAVVPDYLHQDYTATTPHDYLSLIAPLTEGEHIVEAVQATAEECALLHIHAHDPCLLIRRRTWSTTHIVSHARLLFPGSRYRLQGRFGS
>NZ_CP021751.1|WP_004151698.1|1602433_1603390_+|formimidoylglutamase
MMLWQATPASLWQGRDDSAEAPNALRLFQTIVRAERFAPQEMPGDIALLGFACDEGVRRNKGRTGAADGPATLRRALANMASHQGHDRCVDMGTISVDGEQLEAAHQALREAVADCQRVGKRTLVLGGGHETAFGHGAGVLDAFPGEKVGIINLDAHLDLRFADCASSGTPFRQLALECDAQQRGFHYTCIGVSRAANTQALWDEAARRQVAIVEDLEVLTAFETRVLPELERNIAQFDRLYLTIDLDVLPAREMPAVSAPAALGVPLATLLRIVEPLCRNGKLQAVDLVEFNPLFDIDGQGARAAARLAWQIAHWWR
>NZ_CP021751.1|WP_004151697.1|1601219_1602437_+|imidazolonepropionase
MTEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQGDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
>NZ_CP021751.1|WP_004151696.1|1599679_1600963_-|putative-acyl-CoA-thioester-hydrolase
MNTYSVSRLALALAFGVTLSACSSTPADQQPSTQTAPGTTARPILNAEEAKNFTPAAYFQSLAPNAAAWTPSAISLPAQPDFIVGPAGTQGVTHTTIQAAVDAAIARHSNRRLYIAIMPGEYPGTVYVPAAPGALTLYGTGDKPIDVKISEAIDSEMDRNTWRRLVNPGGKYMPGKPAWYMFDSCQSKSAATIGVMCSAVFWSQNNGLQLQNLTIANNLGDSVDAGTHQAVALRSDGDQVQINKVNILGRQNTFFVTNSGVQNRLQDNRQTRTLVTNSYIEGDVDIVSGRGAVVFDNTDFRVVNSRTQKEAYVFAPATLKSVTYGFLATNSRFTASGDNVAQLGRALDVDGNSNGQVVIRDSAINEGFNIAQPWAAAVGSGRPFSGNTGSADDKGNLQRNLNDNGFNRMWEYNNRGVGSTVVAEPKQ
>NZ_CP021751.1|WP_002895284.1|1598060_1598984_-|acyltransferase-family-protein
MTAVTFFTIYNTWDRFDYDYHWILGLLTFISTIATPLFFVVAGYLDAQTRHDANWQIGKIKSVVIVFLFWVTVYYVWEPYQRGYLIQPWFIFALIVIYTFHPLIAWLSQRRGLFFAVLLTLLCCSYGYDLLSVIYPDRHLFSLPPQYRLWTWLLFYLTGQLFNDPKVAEWIRNPQVIKGSIIALPFVYLFTWFYERHFFFALFKADRNAFILTGSQIYILIVLLVIAANAVQFKKNREWKEAVLATVSKAMTGVYILHYSVFHLLVMLIPVHSLATKLGVIALTFVLSVLISLAALSSTLLRKVITL
>NZ_CP021751.1|WP_002895283.1|1597537_1598044_+|hypothetical-protein
MRGKSVMLLAGLASLAQANELNLYSVNTGSYVYHLTNNHGQYTENFENHFFSVERKFSADSKYSLLLGTMNNSFNDRCLALGVRRDWYHSGSGWTFKGVYGYTGEFFFDAFEHCGDHGSYKDFKDATGIGFSPYIYHAIQYNFTDYFAVESGIIIPSVFVISIQWSFR
>NZ_CP021751.1|WP_002895280.1|1596589_1596802_-|hypothetical-protein
MHIKNTIPAEFVFNSALMKNIENTLIKQHRTVNNERMITEIQHRLQTESNEILSDLYLQALDMLYSKPHH
>NZ_CP021751.1|WP_002895575.1|1609790_1610267_-|kinase-inhibitor
MKLISHDLQDGGKLPNRHVFNGMGYDGDNISPHLMWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVANLPADTRVLPQGAGSGQAELPEEAVQTRTDFGKAGYGGAAPPKGETHRYIFTVHALDVEKIEVDAEASGAMVGFNVHFHSLASASITALFS
>NZ_CP021751.1|WP_002895578.1|1610337_1611627_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MTLDDLAFDRRHIWHPYTSMTSPLPVYPVVSAHGCELSLAGGEQLVDGMSSWWAAIHGYNHPRLNAALKGQIDQMSHVMFGGITHPPAVALCRQLVAMTPASLECVFLADSGSVAVEVAMKMALQYWQAKGEPRRRFLTFRNGYHGDTFGAMSVCDPQNSMHSLWQGYLPDNLFAPAPQSRFDGEWDEMDMVPFARLMAAHRHEIAAVILEPIVQGAGGMRMYHPEWLKRVRKMCDREGILLIADEIATGFGRTGKLFACEHAGITADILCLGKALTGGTMTLSAAITTRTVAETISNGEAGCFMHGPTFMGNPLACAVAGESLRLLESGEWQPQVTAIEAQLQAELAPARGSALVADVRVLGAIGVVETRRPVNMAALQRFFVEQGVWIRPFGRLIYLMPPYIITPEQLTRLTRAVNQAVQDETFFSE
>NZ_CP021751.1|WP_002895580.1|1611840_1612881_+|biotin-synthase-BioB
MAHQPRWTMSQVTELFNKPLIDLLFEAQQIHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSARYKTGLEAERLMEVEQVLESARQAKNAGSTRFCMGAAWKNPNDRDMPYLEQMVKGVKALGLESCMTLGTLTDSQAQRLAEAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLDKVRDAGIKVCSGGIVGLGESVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAIARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGINPQQTAVLEGDNEQQQRLEQALLTPDTEEYYNAAAL
>NZ_CP021751.1|WP_004151700.1|1612877_1614035_+|8-amino-7-oxononanoate-synthase
MSWQQRIDRALDERRAAEAFRRRLPVTHGAGRWLEREGERWLNFSSNDYLGLSQHPAIIAAWQQGATRYGVGAGGSGHVSGYSEAHRALEEALVDWLGYPRALLFISGFAANQALIAALVEKDDRIVADRLSHASLLEAASLSPAQLRRFTHNDPQQLAQLLAKPLAGEQLAVTEGIFSMDGDSAPLAAIHAATQAAGAVLLVDDAHGVGVVGDEGRGSCAAQAVRPELLVVTFGKAFGVSGAAVLCDEAMADYLLQFARHLIYSTAMPPAQAVALSAALGIIRSDEGRQRRDILAARIRQFREGMGKVSLGLTDSVSAIQPLIVGDNARALNLACRLRDAGCWATAIRPPTVPVGSARLRLTLTAAHHAEDINRLLEVLHGHSE
>NZ_CP021751.1|WP_004142100.1|1614018_1614774_+|malonyl-ACP-O-methyltransferase-BioC
MATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVTALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPHANRFLSEAAVRAALSGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQLAWPQRQGICPLTYSLFTGVIERD
>NZ_CP021751.1|WP_002895648.1|1614766_1615489_+|ATP-dependent-dethiobiotin-synthetase-BioD
MTKRFFVTGTDTEVGKTIASSALLQAANLLGFHTAGYKPVASGSELTGDGLRNEDALALQRHSRVALRYDQVNPYTFAEPTSPHIISADEGRPIAAARLSSGLRELEGLADWVLVEGAGGWFTPLSDSLTFADWAQAEQLPVILVVGVKLGCINHAMLTAQAVRQAGLPLAGWIANDVQPPGKRHAEYLATLKNRLAAPFLGEIPWLADIAQRDDLGQYLDLRALDPALSTAPAAAHPAP
>NZ_CP021751.1|WP_004152853.1|1615430_1616153_-|ATP-binding-cassette-domain-containing-protein
MLNLQAVNHFYGNQHSLWNVDLVLRPGECIGVLGREGMGKTTLVNCIAGHLPVASGRMTWHDIGAPPQDLTPLSAQSRSAIGIGYVPQDKRIFSQLSVEENLHIALAAGKPGANASGGEIYEHFPELYALRQRKGASLSDDDQYQLALARALIVQPRLLILDEPSRGRGPRCLQKLADLLLRLNRDIGLTVLLAEQHLPFIRRVADRFCVLHRGRNVAEGDIMALDEPLLAQWITPDPAP
>NZ_CP021751.1|WP_002895652.1|1616239_1616452_-|hypothetical-protein
MDNCPQPKTTAARRLSPFAVNRVAKNFYRTIFDNYPLKAARFLLLFAPPFSVGHRKSAAPALTRPDGIGV
>NZ_CP021751.1|WP_002895655.1|1616863_1618885_+|excinuclease-ABC-subunit-B
MSKSFVLHSAFRPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDVFPAESDDIALRIELFDEEVERLSLFDPLTGHVEGTVPRYTIYPKTHYVTPRERIVQAMEEIKLELAERRKVLLANNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVIDESHVTVPQIGGMYRGDRARKETLVEYGFRLPSALDNRPMKFEEFEALAPQTIYVSATPGAYELDKSGGEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRLRTAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQRYNEEHGIVPQGLNKKVVDILQLGQGLAKTKAKGRGKAKAVEPAGLSAVDMTPKALQQKIHELEGQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>NZ_CP021751.1|WP_004151701.1|1619062_1619155_+|hypothetical-protein
MQKINFREYLAVATALVIIVAFFHQWVLTF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP021751_2	2.1\|1223805\|36\|NZ_CP021751\|CRISPRCasFinder	1223805-1223840	36	MK448233	Klebsiella phage ST11-VIM1phi8.1, complete genome	8447-8482	1.0
NZ_CP021751_2	2.1\|1223805\|36\|NZ_CP021751\|CRISPRCasFinder	1223805-1223840	36	MK448235	Klebsiella phage ST512-KPC3phi13.1, complete genome	8447-8482	1.0
NZ_CP021751_2	2.1\|1223805\|36\|NZ_CP021751\|CRISPRCasFinder	1223805-1223840	36	MK448231	Klebsiella phage ST101-KPC2phi6.1, complete genome	11383-11418	1.0

1. spacer 2.1|1223805|36|NZ_CP021751|CRISPRCasFinder matches to MK448233 (Klebsiella phage ST11-VIM1phi8.1, complete genome) position: , mismatch: 0, identity: 1.0

acgcaaacccagtaaccacgctgcgtaccggcgagg	CRISPR spacer
acgcaaacccagtaaccacgctgcgtaccggcgagg	Protospacer
************************************

2. spacer 2.1|1223805|36|NZ_CP021751|CRISPRCasFinder matches to MK448235 (Klebsiella phage ST512-KPC3phi13.1, complete genome) position: , mismatch: 0, identity: 1.0

acgcaaacccagtaaccacgctgcgtaccggcgagg	CRISPR spacer
acgcaaacccagtaaccacgctgcgtaccggcgagg	Protospacer
************************************

3. spacer 2.1|1223805|36|NZ_CP021751|CRISPRCasFinder matches to MK448231 (Klebsiella phage ST101-KPC2phi6.1, complete genome) position: , mismatch: 0, identity: 1.0

acgcaaacccagtaaccacgctgcgtaccggcgagg	CRISPR spacer
acgcaaacccagtaaccacgctgcgtaccggcgagg	Protospacer
************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

991540 : 1003194

Enterobacteria_phage(70.0%)

integrase

attL 979674:979688|attR 1002731:1002745

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
979674:979688	attL	NA	NA	NA	NA
WP_002889890.1\|991540_993874_-	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	82.2
WP_002889897.1\|993885_994206_-	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_002889911.1\|994202_994430_-	hypothetical protein	NA	NA	NA	NA
WP_024940872.1\|994426_994984_-	ash family protein	Q7M2A7	Enterobacteria_phage	1.8e-33	70.4
WP_002889915.1\|994980_995247_-	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	2.6e-30	71.6
WP_002889917.1\|995788_996526_+	hypothetical protein	Q7M2A2	Enterobacteria_phage	9.0e-73	60.7
WP_002889919.1\|996522_996768_+	hypothetical protein	Q7M294	Enterobacteria_phage	1.9e-19	58.0
WP_002889930.1\|996785_997352_+	phage polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.5e-59	64.3
WP_004152979.1\|997920_998346_-	hypothetical protein	NA	NA	NA	NA
WP_004152029.1\|998345_999296_-	cobyrinic acid a,c-diamide synthase	A0A1X9IGI7	Lactococcus_phage	1.2e-13	27.1
WP_002889938.1\|999283_1000474_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	6.4e-145	62.7
WP_002889940.1\|1000826_1002080_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	8.9e-89	44.9
WP_004144574.1\|1002090_1003194_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-62	40.5
1002731:1002745	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1212749 : 1258024

Escherichia_phage(26.42%)

integrase,lysis,tRNA,head

attL 1215632:1215678|attR 1264766:1264812

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004143010.1\|1212749_1214135_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.5e-46	35.4
WP_004143016.1\|1214180_1214393_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_004143017.1\|1214394_1215261_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-30	34.8
1215632:1215678	attL	NA	NA	NA	NA
WP_004151318.1\|1215691_1216855_-\|integrase	site-specific integrase	G8C7S0	Escherichia_phage	3.3e-202	87.3
WP_004151317.1\|1216731_1217067_-	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_004151316.1\|1217068_1217284_-	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	4.0e-13	52.9
WP_004151314.1\|1217285_1217504_-	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.2e-09	47.2
WP_004151312.1\|1217500_1218268_-	hypothetical protein	D5LH17	Escherichia_phage	1.7e-66	53.4
WP_004151310.1\|1218264_1218921_-	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-113	87.5
WP_004151308.1\|1218917_1219076_-	DUF1317 family protein	A0A0N7CHV0	Escherichia_phage	3.0e-10	60.8
WP_004151306.1\|1219072_1219753_-	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	7.9e-124	93.4
WP_004151305.1\|1219749_1220595_-	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	6.9e-69	59.2
WP_004151304.1\|1220610_1220895_-	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	8.0e-30	62.8
WP_004151303.1\|1220983_1221178_-	hypothetical protein	NA	NA	NA	NA
WP_004151301.1\|1221277_1221493_-	hypothetical protein	B5WZV1	Pseudomonas_phage	1.6e-09	48.6
WP_004151300.1\|1221843_1222533_-	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	4.3e-61	52.2
WP_004151299.1\|1222660_1222894_+	helix-turn-helix domain-containing protein	G8C7U2	Escherichia_phage	4.3e-13	50.7
WP_001548453.1\|1222934_1223156_+	hypothetical protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_004151297.1\|1223380_1224280_+	hypothetical protein	F1C5C3	Cronobacter_phage	5.4e-88	54.9
WP_004151296.1\|1224269_1225700_+	AAA family ATPase	Q9MCT4	Escherichia_phage	2.6e-185	66.7
WP_004151295.1\|1225699_1225993_+	protein ren	O48423	Enterobacteria_phage	3.3e-26	65.6
WP_004151294.1\|1225989_1226496_+	hypothetical protein	A0A0A6Z565	Enterobacter_phage	3.0e-27	59.6
WP_004151293.1\|1226602_1227445_+	translation repressor RelE	A0A2H4FRZ0	Salmonella_phage	1.8e-29	60.8
WP_004151291.1\|1227617_1228265_+	DUF551 domain-containing protein	A5LH60	Enterobacteria_phage	4.5e-12	32.6
WP_004151288.1\|1228765_1229221_+	hypothetical protein	K7P7B8	Enterobacteria_phage	8.0e-56	69.5
WP_004151287.1\|1229220_1229391_+	NinE family protein	G8C7V4	Escherichia_phage	1.3e-14	73.2
WP_004151286.1\|1229383_1230019_+	protein ninG	M9NYX8	Enterobacteria_phage	2.7e-81	77.9
WP_004151285.1\|1230015_1230153_+	YlcG family protein	NA	NA	NA	NA
WP_004151284.1\|1230145_1230676_+	HNH endonuclease	A0A193GYW9	Enterobacter_phage	5.2e-30	43.1
WP_004151283.1\|1230672_1231362_+	antitermination protein	I6PDF8	Cronobacter_phage	1.4e-56	54.5
WP_004151282.1\|1232271_1232520_+	hypothetical protein	NA	NA	NA	NA
WP_004151281.1\|1232522_1233053_+	lysozyme	G9L6J6	Escherichia_phage	6.0e-79	78.5
WP_004151280.1\|1233049_1233514_+\|lysis	lysis protein	Q76H63	Enterobacteria_phage	2.4e-55	73.2
WP_004151279.1\|1233619_1233949_-	hypothetical protein	NA	NA	NA	NA
WP_004151277.1\|1234319_1234922_+	hypothetical protein	G8C7P2	Escherichia_phage	5.4e-76	80.9
WP_004151276.1\|1234921_1236394_+	hypothetical protein	A0A1W6JNY3	Morganella_phage	1.3e-248	82.5
WP_004151275.1\|1236406_1237828_+	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	9.6e-148	57.1
WP_004151274.1\|1237802_1238807_+\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	9.0e-116	69.7
WP_004151273.1\|1238848_1239325_+	hypothetical protein	NA	NA	NA	NA
WP_004151272.1\|1239397_1240783_+	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	2.3e-154	60.0
WP_004151271.1\|1240786_1241215_+	hypothetical protein	F1C5E0	Cronobacter_phage	1.6e-42	60.8
WP_004151270.1\|1241226_1242321_+	hypothetical protein	F1C5E1	Cronobacter_phage	1.7e-123	62.8
WP_004151269.1\|1242331_1242571_+	hypothetical protein	NA	NA	NA	NA
WP_004151268.1\|1242573_1242954_+	hypothetical protein	F1C5E2	Cronobacter_phage	5.3e-29	55.3
WP_004151267.1\|1242953_1243127_+	hypothetical protein	I6R0P9	Salmonella_phage	1.4e-13	56.1
WP_004151266.1\|1243126_1243489_+	hypothetical protein	A0A173GCE0	Salmonella_phage	1.8e-18	45.0
WP_004151265.1\|1243491_1243917_+	hypothetical protein	R9TPP7	Aeromonas_phage	5.1e-28	47.9
WP_004151264.1\|1243913_1244306_+	hypothetical protein	G0ZNE4	Cronobacter_phage	5.1e-35	52.7
WP_004151263.1\|1244374_1245127_+	Ig domain-containing protein	G0ZNE6	Cronobacter_phage	5.8e-43	42.1
WP_004151262.1\|1245179_1245857_+	hypothetical protein	F1C5E8	Cronobacter_phage	4.8e-73	57.9
WP_004151261.1\|1246032_1246788_+	DNA-binding protein	K7PGT4	Enterobacteria_phage	2.4e-60	51.0
WP_004151260.1\|1246790_1247045_+	hypothetical protein	K7PM89	Enterobacteria_phage	6.7e-20	73.0
WP_004151259.1\|1247338_1247809_+	hypothetical protein	NA	NA	NA	NA
WP_004151258.1\|1247825_1248185_-	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.8e-16	47.5
WP_004151257.1\|1248284_1248455_+	Arc family DNA-binding protein	I6R9A8	Salmonella_phage	6.1e-17	87.0
WP_004151256.1\|1248444_1249158_+	hypothetical protein	H6WRU8	Salmonella_phage	3.9e-49	50.2
WP_004151255.1\|1249223_1250009_+	phage repressor protein	A0A2L1IV39	Escherichia_phage	1.9e-84	59.7
WP_004151254.1\|1250136_1250640_+	hypothetical protein	NA	NA	NA	NA
WP_004151253.1\|1250732_1254179_+	tape measure protein	Q5G8W8	Enterobacteria_phage	1.4e-163	48.6
WP_004165520.1\|1254278_1254698_+	hypothetical protein	A0A2P1MXB5	Escherichia_phage	1.8e-30	48.5
WP_004199076.1\|1254697_1255168_+	hypothetical protein	R9TPR6	Aeromonas_phage	2.5e-28	41.0
WP_004151250.1\|1255164_1255560_+	hypothetical protein	F1C5F2	Cronobacter_phage	8.0e-36	54.0
WP_004151249.1\|1255546_1258024_+	MoaD/ThiS family protein	F1C5A7	Cronobacter_phage	2.7e-198	45.6
1264766:1264812	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1703134 : 1740470

Salmonella_phage(84.62%)

terminase,integrase,head,lysis,capsid,portal,tail,plate

attL 1703042:1703060|attR 1740542:1740560

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1703042:1703060	attL	NA	NA	NA	NA
WP_004151720.1\|1703134_1704187_-\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.0e-106	57.0
WP_004152765.1\|1704605_1706090_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004150866.1\|1706188_1707133_-	hypothetical protein	NA	NA	NA	NA
WP_004152885.1\|1707144_1708023_-	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.7e-30	39.9
WP_000188448.1\|1708168_1708390_+	hypothetical protein	NA	NA	NA	NA
WP_000460893.1\|1708422_1708932_+	phage regulatory CII family protein	E5G6L3	Salmonella_phage	5.8e-87	98.8
WP_000956179.1\|1708939_1709140_+	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	1.6e-32	97.0
WP_000963473.1\|1709103_1709445_+	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	4.6e-56	99.1
WP_004150864.1\|1709512_1709746_+	DUF2732 family protein	E5G6L6	Salmonella_phage	4.1e-32	96.1
WP_000752622.1\|1709745_1709973_+	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	6.0e-36	98.7
WP_004150863.1\|1709969_1710827_+	DNA adenine methylase	E5G6L8	Salmonella_phage	2.0e-156	95.4
WP_004150862.1\|1710823_1713238_+	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.5
WP_001154434.1\|1713391_1713580_+	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_001217575.1\|1713590_1713824_+	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_000700647.1\|1713938_1714616_+	hypothetical protein	NA	NA	NA	NA
WP_004199124.1\|1714891_1716634_+	AIPR family protein	NA	NA	NA	NA
WP_002895959.1\|1716695_1717721_-\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	7.6e-171	86.7
WP_004150858.1\|1717720_1719487_-\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.0
WP_002895967.1\|1719629_1720463_+\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	6.3e-123	88.8
WP_002895972.1\|1720479_1721538_+\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	1.1e-180	93.1
WP_000059191.1\|1721541_1722192_+\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
WP_002896151.1\|1722287_1722752_+\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	8.4e-77	89.0
WP_002896155.1\|1722751_1722955_+\|tail	tail protein X	A0A1S6KZY4	Salmonella_phage	1.3e-29	88.1
WP_002896158.1\|1722958_1723174_+	hypothetical protein	E5G6N0	Salmonella_phage	3.6e-30	90.1
WP_002896161.1\|1723154_1723664_+	lysozyme	E5G6N1	Salmonella_phage	2.1e-81	83.4
WP_002896163.1\|1723668_1724052_+	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	2.1e-17	42.0
WP_002896168.1\|1724048_1724477_+\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	9.6e-51	77.9
WP_002896172.1\|1724572_1725004_+\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	9.9e-64	82.5
WP_002896175.1\|1724996_1725443_+	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.2e-50	71.2
WP_004150857.1\|1725439_1726132_-	hypothetical protein	NA	NA	NA	NA
WP_002896177.1\|1726226_1726799_+\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	4.7e-77	72.3
WP_002896179.1\|1726795_1727158_+\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	5.8e-49	84.7
WP_002896182.1\|1727144_1728053_+\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	7.6e-106	66.9
WP_004150856.1\|1728045_1728645_+\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.3e-58	60.5
WP_004152882.1\|1728646_1731598_+	hypothetical protein	A0A2H4N7A3	Pectobacterium_phage	1.2e-06	50.9
WP_002896186.1\|1731601_1732333_+	hypothetical protein	NA	NA	NA	NA
WP_002896188.1\|1732329_1732533_+	hypothetical protein	NA	NA	NA	NA
WP_002896191.1\|1732562_1733639_+\|tail	phage tail protein	Q37842	Escherichia_phage	1.2e-25	44.8
WP_002896193.1\|1733777_1734950_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.9e-210	93.3
WP_002896201.1\|1734959_1735475_+\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	1.3e-81	85.4
WP_002896204.1\|1735527_1735827_+\|tail	phage tail assembly protein	E5G6P9	Salmonella_phage	3.7e-33	79.0
WP_002896220.1\|1735841_1735961_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.2e-13	87.2
WP_002896222.1\|1735953_1738581_+\|tail	phage tail tape measure protein	E5FFG5	Burkholderia_phage	5.6e-117	42.0
WP_002896224.1\|1738577_1739063_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	7.2e-63	75.6
WP_002896225.1\|1739059_1740160_+	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	4.9e-176	87.4
WP_000972391.1\|1740251_1740470_+	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	7.5e-20	69.0
1740542:1740560	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1774886 : 1784350

Dickeya_phage(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002896440.1\|1774886_1776002_+	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_004150848.1\|1775998_1777939_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_002896516.1\|1778015_1778237_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_002896520.1\|1778562_1778880_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896522.1\|1778910_1781190_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_001040187.1\|1781310_1781529_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_002898014.1\|1781882_1782584_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_004150847.1\|1782628_1784350_-	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3

DBSCAN-SWA_5

2172379 : 2230195

Enterobacteria_phage(20.75%)

terminase,integrase,transposase,holin,tail

attL 2164357:2164372|attR 2187196:2187211

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2164357:2164372	attL	NA	NA	NA	NA
WP_004140269.1\|2172379_2173189_-	peptide ABC transporter ATP-binding protein SapF	A0A2H4PQG7	Staphylococcus_phage	2.1e-14	28.9
WP_004140266.1\|2173190_2174183_-	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	3.0e-07	27.2
WP_004151901.1\|2174182_2175073_-	peptide ABC transporter permease SapC	NA	NA	NA	NA
WP_004153574.1\|2175249_2176437_+\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	1.1e-120	52.4
WP_004151899.1\|2176644_2177307_-	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-105	84.6
WP_004151898.1\|2177303_2177732_-	hypothetical protein	M9NYX4	Enterobacteria_phage	7.5e-64	80.3
WP_004201102.1\|2177728_2178409_-	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	8.2e-121	91.2
WP_088224434.1\|2178410_2178698_-	hypothetical protein	NA	NA	NA	NA
WP_004201103.1\|2178694_2179540_-	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	1.8e-69	59.2
WP_004201105.1\|2179555_2179840_-	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	1.1e-39	79.8
WP_004135674.1\|2179928_2180123_-	hypothetical protein	NA	NA	NA	NA
WP_004201108.1\|2180551_2180755_+	hypothetical protein	A0A192Y6Q5	Salmonella_phage	3.9e-18	71.6
WP_004201109.1\|2180836_2181913_-	ParA family protein	H2BD62	Pseudomonas_phage	9.1e-58	37.9
WP_019405077.1\|2182058_2182178_-	hypothetical protein	NA	NA	NA	NA
WP_004201113.1\|2182200_2182899_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	3.7e-108	84.1
WP_004201115.1\|2183010_2183238_+	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	1.4e-24	77.1
WP_001548453.1\|2183278_2183500_+	hypothetical protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_004201117.1\|2183585_2184446_+	replication protein	K7PGT1	Enterobacteria_phage	1.0e-59	53.3
WP_004201118.1\|2184442_2185291_+	AAA family ATPase	K7PLU3	Enterobacteria_phage	5.1e-88	60.1
WP_004218528.1\|2185287_2185590_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004196831.1\|2185645_2185891_+	hypothetical protein	NA	NA	NA	NA
WP_004218530.1\|2186098_2187127_-	hypothetical protein	NA	NA	NA	NA
WP_004218531.1\|2187647_2188115_+	recombination protein NinB	Q8VNP6	Enterobacteria_phage	3.4e-33	45.8
2187196:2187211	attR	NA	NA	NA	NA
WP_004243010.1\|2188095_2188263_+	NinE family protein	K7P7K0	Enterobacteria_phage	4.6e-09	62.5
WP_004218532.1\|2188259_2188928_+	serine/threonine protein phosphatase	K7P6H8	Enterobacteria_phage	1.4e-104	78.7
WP_004218533.1\|2188920_2189559_+	hypothetical protein	H6WRY9	Salmonella_phage	3.2e-74	69.8
WP_004218534.1\|2189555_2189696_+	YlcG family protein	NA	NA	NA	NA
WP_004232548.1\|2189695_2190385_+	antiterminator-like protein	I6PDF8	Cronobacter_phage	2.1e-55	53.1
WP_024940884.1\|2191034_2191334_+\|holin	holin	A0A286N2Q5	Klebsiella_phage	4.5e-47	100.0
WP_004218565.1\|2191330_2191870_+	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	3.3e-101	98.9
WP_004190674.1\|2191866_2192211_+	hypothetical protein	A0A286N2Q7	Klebsiella_phage	2.0e-38	80.7
WP_004190672.1\|2192207_2192483_+	hypothetical protein	A0A286N2Q8	Klebsiella_phage	2.2e-08	72.5
WP_004218558.1\|2193441_2193687_+	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	4.6e-34	96.3
WP_004218556.1\|2194549_2195554_+\|terminase	terminase small subunit	Q5QF76	Pseudomonas_virus	1.5e-38	45.5
WP_004190663.1\|2195531_2196839_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	3.6e-149	58.9
WP_004218551.1\|2196838_2198239_+	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	1.1e-127	53.5
WP_019405022.1\|2198222_2199335_+	hypothetical protein	I6PD76	Cronobacter_phage	5.6e-111	55.1
WP_004217351.1\|2199865_2200651_+	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	1.0e-66	63.9
WP_004190653.1\|2200661_2201615_+	Ig domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	5.0e-132	74.4
WP_004217348.1\|2201936_2202332_+	hypothetical protein	A0A1B1P9F2	Acinetobacter_phage	4.3e-13	38.5
WP_004217346.1\|2202333_2202588_+	hypothetical protein	J9Q7U0	Salmonella_phage	1.0e-20	52.4
WP_004190646.1\|2202597_2202831_+	hypothetical protein	A0A2H4J0Y9	uncultured_Caudovirales_phage	5.8e-10	47.1
WP_004217344.1\|2202817_2203201_+	hypothetical protein	A0A0S2SYG4	Pseudomonas_phage	7.1e-21	45.2
WP_004217343.1\|2203202_2203754_+	hypothetical protein	G8C7Q1	Escherichia_phage	1.3e-28	39.9
WP_004190640.1\|2203750_2204143_+	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_004217341.1\|2204166_2205339_+	Ig domain-containing protein	A0A0D4DBN5	Acinetobacter_phage	1.2e-23	27.0
WP_004226994.1\|2205392_2205875_+	hypothetical protein	NA	NA	NA	NA
WP_016831940.1\|2206012_2206219_+	hypothetical protein	NA	NA	NA	NA
WP_004217333.1\|2206295_2206652_+	hypothetical protein	A0A1V0E5P9	Salmonella_phage	1.1e-44	75.0
WP_099119318.1\|2206876_2207068_+	hypothetical protein	S4TR42	Salmonella_phage	7.8e-05	78.3
WP_004217331.1\|2207329_2210227_+\|tail	tail protein	A0A2H4J107	uncultured_Caudovirales_phage	1.6e-104	32.7
WP_004152648.1\|2210310_2210646_+	hypothetical protein	NA	NA	NA	NA
WP_004152649.1\|2210960_2211425_+	hypothetical protein	A0A286S298	Klebsiella_phage	6.7e-58	67.8
WP_004152650.1\|2211605_2212088_+	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	1.7e-80	94.4
WP_004152651.1\|2212097_2212478_+	hypothetical protein	A0A286S2A6	Klebsiella_phage	1.8e-72	99.2
WP_004152652.1\|2212474_2215543_+	hypothetical protein	A0A286S259	Klebsiella_phage	0.0e+00	97.5
WP_022644627.1\|2215619_2218574_+	hypothetical protein	A0A286S1P0	Klebsiella_phage	4.2e-44	68.3
WP_004152700.1\|2218577_2219309_+	hypothetical protein	NA	NA	NA	NA
WP_004152702.1\|2219533_2220133_-	hypothetical protein	NA	NA	NA	NA
WP_004152703.1\|2220374_2222318_-	hypothetical protein	A0A286S1P0	Klebsiella_phage	1.1e-37	69.8
WP_001067855.1\|2222566_2223271_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004152776.1\|2223863_2224286_+	hypothetical protein	K7P834	Enterobacteria_phage	3.6e-26	45.3
WP_004152765.1\|2225183_2226668_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_002901812.1\|2226747_2227167_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.4e-35	57.5
WP_002901813.1\|2227168_2228434_+	Y-family DNA polymerase	I6RSM4	Salmonella_phage	9.6e-208	82.7
WP_071531199.1\|2228509_2229337_-	FRG domain-containing protein	A0A1S6KZX9	Salmonella_phage	8.4e-19	30.2
WP_002901815.1\|2229523_2230195_-	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	4.5e-79	59.6

DBSCAN-SWA_6

2263128 : 2302900

uncultured_Caudovirales_phage(35.42%)

terminase,integrase,transposase

attL 2261209:2261223|attR 2270149:2270163

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2261209:2261223	attL	NA	NA	NA	NA
WP_004152144.1\|2263128_2263890_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-20	32.5
WP_004152145.1\|2264106_2265639_+	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	1.1e-21	30.0
WP_016197745.1\|2265837_2266386_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_004152147.1\|2266582_2267764_+\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	5.6e-202	84.2
WP_004152148.1\|2267744_2267987_-	hypothetical protein	A0A0M4RTZ2	Salmonella_phage	2.2e-20	73.8
WP_004152149.1\|2268165_2268645_-	hypothetical protein	NA	NA	NA	NA
WP_004152150.1\|2268641_2268854_-	hypothetical protein	A0A286S2B6	Klebsiella_phage	3.4e-33	98.6
WP_004152151.1\|2268850_2269075_-	hypothetical protein	A0A286S2B3	Klebsiella_phage	3.1e-29	89.2
WP_004154298.1\|2269064_2269775_-	DNA-binding protein	A0A286S260	Klebsiella_phage	2.1e-111	88.3
WP_004152153.1\|2269780_2270299_-	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.7e-94	98.8
2270149:2270163	attR	NA	NA	NA	NA
WP_004152154.1\|2270403_2271231_-	hypothetical protein	Q8W654	Enterobacteria_phage	5.5e-111	84.0
WP_004152155.1\|2271227_2271422_-	hypothetical protein	NA	NA	NA	NA
WP_004152156.1\|2271418_2271844_-	hypothetical protein	A0A286S1S2	Klebsiella_phage	3.5e-53	77.9
WP_004177208.1\|2271840_2272059_-	hypothetical protein	A0A286S1P6	Klebsiella_phage	6.6e-32	98.6
WP_004152157.1\|2272030_2272285_-	hypothetical protein	A0A286SGR4	Klebsiella_phage	3.1e-41	97.6
WP_004152158.1\|2272277_2272643_-	hypothetical protein	A0A286S1Q6	Klebsiella_phage	6.9e-58	99.2
WP_004152159.1\|2272812_2273001_-	hypothetical protein	A0A286S1P8	Klebsiella_phage	4.6e-26	100.0
WP_004152160.1\|2272993_2273308_-	hypothetical protein	A0A286S1T9	Klebsiella_phage	1.0e-49	100.0
WP_004152161.1\|2273478_2274147_-	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	2.4e-125	99.5
WP_004152162.1\|2274244_2274466_+	helix-turn-helix transcriptional regulator	A0A286S2C1	Klebsiella_phage	3.0e-32	100.0
WP_004198228.1\|2275042_2276701_+	DEAD/DEAH box helicase	A0A286N2P9	Klebsiella_phage	0.0e+00	96.0
WP_004198233.1\|2276702_2277665_+	zinc-binding domain of primase-helicase family protein	A0A286N2Q0	Klebsiella_phage	4.8e-183	99.4
WP_004198239.1\|2277661_2278138_+	hypothetical protein	A0A286N2Q1	Klebsiella_phage	1.8e-90	100.0
WP_004152167.1\|2278134_2278917_+	antitermination protein	F1C595	Cronobacter_phage	7.2e-113	76.8
WP_004146526.1\|2279322_2279571_+	hypothetical protein	NA	NA	NA	NA
WP_004152169.1\|2279573_2280104_+	lysozyme	K7PLY1	Enterobacteria_phage	2.7e-79	77.1
WP_004153952.1\|2280100_2280490_+	lipase chaperone	A0A192Y6H8	Salmonella_phage	9.4e-21	49.2
WP_004152170.1\|2280724_2281045_+	hypothetical protein	NA	NA	NA	NA
WP_004152171.1\|2281146_2281899_+	hypothetical protein	A0A077KBY7	Edwardsiella_phage	4.0e-12	66.0
WP_004152172.1\|2281849_2283250_+\|terminase	PBSX family phage terminase large subunit	A0A077KAW0	Edwardsiella_phage	9.4e-188	69.0
WP_004152173.1\|2283487_2284939_+	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	3.8e-192	68.8
WP_004152174.1\|2284994_2285543_+	hypothetical protein	A0A0M4REK0	Salmonella_phage	3.0e-49	56.3
WP_004199270.1\|2285594_2286797_+	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	2.6e-106	54.1
WP_000528476.1\|2286800_2287295_+	hypothetical protein	A0A2H4JHM9	uncultured_Caudovirales_phage	4.2e-50	62.7
WP_001132269.1\|2287306_2288248_+	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	1.7e-137	77.1
WP_000725700.1\|2288287_2288569_+	hypothetical protein	NA	NA	NA	NA
WP_000113538.1\|2288537_2288957_+	DUF4054 domain-containing protein	A0A0M5M3S2	Salmonella_phage	3.3e-40	60.7
WP_000834982.1\|2288953_2289460_+	hypothetical protein	NA	NA	NA	NA
WP_001116156.1\|2289459_2289846_+	hypothetical protein	A0A2H4J1A4	uncultured_Caudovirales_phage	1.1e-48	78.2
WP_004152176.1\|2289940_2290381_+	hypothetical protein	A0A2H4J1A0	uncultured_Caudovirales_phage	1.6e-40	51.7
WP_004152177.1\|2290384_2291530_+	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	6.3e-166	76.9
WP_004152178.1\|2291540_2291831_+	DUF3277 family protein	A0A2H4J619	uncultured_Caudovirales_phage	2.6e-23	85.5
WP_085955245.1\|2291771_2292964_-\|transposase	IS3-like element ISKpn18 family transposase	U5P429	Shigella_phage	3.5e-50	43.5
WP_004152564.1\|2293290_2293716_+	hypothetical protein	A0A2H4J2V6	uncultured_Caudovirales_phage	2.6e-40	63.4
WP_004152565.1\|2293751_2293904_+	hypothetical protein	A0A2H4J1A2	uncultured_Caudovirales_phage	7.6e-19	88.0
WP_004152566.1\|2293893_2295897_+	lytic transglycosylase domain-containing protein	A0A2H4J9N7	uncultured_Caudovirales_phage	1.2e-247	63.6
WP_004152567.1\|2295896_2296496_+	hypothetical protein	A0A2H4J1B3	uncultured_Caudovirales_phage	9.9e-54	57.6
WP_004152568.1\|2296496_2296799_+	hypothetical protein	A0A2H4J495	uncultured_Caudovirales_phage	2.0e-26	55.2
WP_004152569.1\|2296801_2297824_+	hypothetical protein	A0A2H4J1B2	uncultured_Caudovirales_phage	9.2e-100	54.2
WP_004152570.1\|2297823_2298165_+	hypothetical protein	A0A2H4J1A5	uncultured_Caudovirales_phage	1.8e-23	46.6
WP_004199301.1\|2298214_2298397_+	hypothetical protein	NA	NA	NA	NA
WP_004152571.1\|2298439_2299006_+	hypothetical protein	NA	NA	NA	NA
WP_004152572.1\|2299059_2299713_+	hypothetical protein	A0A2H4J8H6	uncultured_Caudovirales_phage	1.0e-59	63.5
WP_004152573.1\|2299714_2300068_+	hypothetical protein	A0A2H4J629	uncultured_Caudovirales_phage	2.3e-50	80.3
WP_004152574.1\|2300067_2301264_+	hypothetical protein	A0A0M4RD32	Salmonella_phage	3.9e-158	72.9
WP_004152575.1\|2301260_2302034_+	DUF2612 domain-containing protein	A0A2H4J1A9	uncultured_Caudovirales_phage	2.8e-77	54.4
WP_004152576.1\|2302033_2302900_+	hypothetical protein	A0A2H4IYR0	uncultured_Caudovirales_phage	1.9e-34	64.5

DBSCAN-SWA_7

2526270 : 2537157

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210516.1\|2526270_2526891_-	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0
WP_004151609.1\|2526883_2528149_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	6.6e-233	99.5
WP_004151610.1\|2528160_2529063_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	7.7e-159	99.3
WP_002210513.1\|2529323_2530085_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004176269.1\|2530105_2530966_-	class A broad-spectrum beta-lactamase SHV-11	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002904006.1\|2531263_2531524_+	hypothetical protein	A0A077SK33	Escherichia_phage	3.5e-40	97.7
WP_001620097.1\|2531610_2532699_+	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_004151612.1\|2532729_2533995_-	MFS transporter	NA	NA	NA	NA
WP_004151613.1\|2534049_2537157_-	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6

DBSCAN-SWA_8

3192934 : 3236033

Microcystis_virus(25.0%)

transposase,tRNA,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002910404.1\|3192934_3194191_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_002910405.1\|3194461_3195073_+	lipoprotein localization protein LolB	NA	NA	NA	NA
WP_002910406.1\|3195069_3195921_+	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_002910407.1\|3196104_3197052_+	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	2.3e-44	37.5
WP_004152259.1\|3197176_3198856_+	C4-dicarboxylic acid transporter DauA	A0A2H4J153	uncultured_Caudovirales_phage	7.9e-24	23.4
WP_002910436.1\|3198856_3199903_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_002910437.1\|3200125_3200401_-	stress-induced protein YchH	NA	NA	NA	NA
WP_002910438.1\|3200673_3201258_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_002910443.1\|3201375_3202467_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_002910446.1\|3202549_3202759_-	DUF1869 domain-containing protein	NA	NA	NA	NA
WP_002910453.1\|3202960_3203875_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004152260.1\|3204006_3205422_-	membrane protein	NA	NA	NA	NA
WP_004152261.1\|3205441_3205885_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002910493.1\|3205887_3206424_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002910494.1\|3206404_3207451_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002910495.1\|3207450_3209214_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004152262.1\|3209347_3212758_-	type VI secretion protein VasK	NA	NA	NA	NA
WP_004198077.1\|3212741_3213899_-	hypothetical protein	NA	NA	NA	NA
WP_002910497.1\|3213902_3214169_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_004227463.1\|3214466_3214724_-	hypothetical protein	NA	NA	NA	NA
WP_029779706.1\|3214912_3215149_-	hypothetical protein	NA	NA	NA	NA
WP_000019473.1\|3215272_3216253_-\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_004152632.1\|3216589_3217480_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7H6	Microcystis_virus	4.1e-11	29.8
WP_002910539.1\|3217655_3218549_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	2.8e-12	27.1
WP_004152633.1\|3218724_3219618_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	1.7e-12	27.3
WP_002910544.1\|3219801_3220695_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7H6	Microcystis_virus	6.7e-14	30.5
WP_002910547.1\|3220716_3221022_-	hypothetical protein	NA	NA	NA	NA
WP_004155011.1\|3221045_3222155_-	hypothetical protein	NA	NA	NA	NA
WP_002910549.1\|3222260_3222491_-	hypothetical protein	NA	NA	NA	NA
WP_002910551.1\|3222536_3223043_-	hypothetical protein	NA	NA	NA	NA
WP_004153085.1\|3223039_3223369_-	hypothetical protein	NA	NA	NA	NA
WP_004199326.1\|3223365_3223548_-	hypothetical protein	NA	NA	NA	NA
WP_004153456.1\|3223689_3224613_-\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	1.6e-172	97.1
WP_002910586.1\|3226263_3226773_-	hypothetical protein	NA	NA	NA	NA
WP_002910591.1\|3227009_3227516_-	hypothetical protein	NA	NA	NA	NA
WP_002910593.1\|3227512_3228022_-	hypothetical protein	NA	NA	NA	NA
WP_004152319.1\|3228022_3229378_-	hypothetical protein	NA	NA	NA	NA
WP_004152317.1\|3232341_3234039_-	OmpA family protein	NA	NA	NA	NA
WP_004152316.1\|3234042_3234696_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002910645.1\|3234692_3236033_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_9

3503721 : 3511346

Escherichia_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152482.1\|3503721_3504723_-	NAD-dependent epimerase	E3T4Y8	Cafeteria_roenbergensis_virus	1.2e-30	28.6
WP_004152483.1\|3504916_3506083_-	UDP-glucose 6-dehydrogenase	M1I798	Paramecium_bursaria_Chlorella_virus	4.1e-112	54.7
WP_004152484.1\|3506263_3506818_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	3.8e-52	58.2
WP_004152485.1\|3506832_3507723_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.8e-28	33.6
WP_004152486.1\|3507754_3508624_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	9.8e-111	67.0
WP_004152487.1\|3508650_3509715_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.4e-105	55.0
WP_004152488.1\|3509939_3511346_-	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	4.7e-38	28.7

DBSCAN-SWA_10

3547913 : 3554820

Bacillus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004151135.1\|3547913_3549392_+	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	1.1e-29	28.3
WP_002912634.1\|3549388_3550111_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	6.4e-31	33.2
WP_002912635.1\|3550429_3551791_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	2.5e-206	94.5
WP_002912636.1\|3552036_3552930_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
WP_002912638.1\|3553172_3553946_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-25	36.3
WP_004175147.1\|3553956_3554820_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5

DBSCAN-SWA_11

3959968 : 4039578

Salmonella_phage(71.43%)

terminase,integrase,head,lysis,capsid,coat,portal,tRNA,tail,plate

attL 4004672:4004718|attR 4041239:4041285

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002914079.1\|3959968_3960706_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_002914082.1\|3960837_3962169_+	ATP-dependent RNA helicase SrmB	E3T5E1	Cafeteria_roenbergensis_virus	6.2e-48	31.9
WP_002914084.1\|3962214_3962598_-	autonomous glycyl radical cofactor GrcA	A0A193GZ98	Escherichia_phage	4.0e-32	79.3
WP_002914088.1\|3962911_3963601_+	uracil-DNA glycosylase	A0A077BCN4	Equid_alphaherpesvirus	1.3e-57	53.0
WP_002914089.1\|3963658_3964744_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_002914091.1\|3964947_3965373_+	thioredoxin TrxC	A0A1J0GW78	Streptomyces_phage	6.0e-13	40.2
WP_002914092.1\|3965442_3966141_+	DTW domain-containing protein	NA	NA	NA	NA
WP_004151994.1\|3966175_3968836_+	protein lysine acetyltransferase	NA	NA	NA	NA
WP_002914094.1\|3968956_3970312_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_002914095.1\|3970353_3970677_+	YfiM family lipoprotein	NA	NA	NA	NA
WP_002914097.1\|3970680_3971979_-	MFS transporter	Q6JIH2	Burkholderia_virus	3.1e-44	31.5
WP_004150973.1\|3977944_3980518_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	6.9e-128	35.4
WP_002914109.1\|3980647_3981379_-	polyphenol oxidase	NA	NA	NA	NA
WP_002914110.1\|3981375_3982356_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_004145664.1\|3982487_3983225_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_002914111.1\|3983495_3983831_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_100250063.1\|3983937_3983985_+	hypothetical protein	NA	NA	NA	NA
WP_004150975.1\|3984085_3985246_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_002914112.1\|3985242_3986115_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_002914113.1\|3986177_3987299_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_002914114.1\|3987308_3988379_-	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	1.8e-90	51.5
WP_004174804.1\|3988721_3989231_+	YfiR family protein	NA	NA	NA	NA
WP_002914116.1\|3989223_3990447_+	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_002914117.1\|3990460_3990943_+	OmpA family protein	NA	NA	NA	NA
WP_002914118.1\|3990951_3992322_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_002914119.1\|3992378_3992837_-	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_002914145.1\|3992956_3993304_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_002914147.1\|3993343_3994111_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_004150977.1\|3994142_3994691_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_002914149.1\|3994709_3994958_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_002914152.1\|3995217_3996582_-	signal recognition particle protein	NA	NA	NA	NA
WP_002914153.1\|3996745_3997537_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_004149392.1\|3997556_3998843_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_002914155.1\|3998962_3999553_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_002914158.1\|3999677_4000556_+	NAD(+) kinase	NA	NA	NA	NA
WP_002914159.1\|4000642_4002304_+	DNA repair protein RecN	NA	NA	NA	NA
WP_002914160.1\|4002451_4002793_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_002914161.1\|4002859_4003150_-	RnfH family protein	NA	NA	NA	NA
WP_004188817.1\|4003139_4003616_-	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_002914164.1\|4003726_4004209_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.3e-29	47.4
4004672:4004718	attL	NA	NA	NA	NA
WP_004150980.1\|4004812_4005190_+	hypothetical protein	NA	NA	NA	NA
WP_004150981.1\|4005217_4005436_-	positive regulator of late gene transcription	Q53ZE7	Salmonella_virus	1.9e-26	72.2
WP_004150982.1\|4005502_4006597_-	phage late control D family protein	E5G6Q3	Salmonella_phage	2.4e-170	83.6
WP_004150983.1\|4006593_4007079_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	5.2e-61	80.1
WP_004150984.1\|4007075_4009706_-\|tail	phage tail tape measure protein	E5FFG5	Burkholderia_phage	8.9e-115	41.9
WP_002896220.1\|4009698_4009818_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.2e-13	87.2
WP_004150985.1\|4009832_4010132_-\|tail	phage tail assembly protein	E5G6P9	Salmonella_phage	8.2e-33	78.0
WP_004150986.1\|4010184_4010700_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	1.4e-80	84.2
WP_004150987.1\|4010709_4011882_-\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	3.4e-207	91.5
WP_004150988.1\|4012030_4013104_-\|tail	phage tail protein	A0A1S6KZZ8	Salmonella_phage	6.6e-40	53.6
WP_004200602.1\|4013155_4014274_-	hypothetical protein	A0A248XD67	Klebsiella_phage	4.4e-55	38.0
WP_004150990.1\|4014283_4016233_-\|coat	spore coat protein CotH	Q6QI97	Burkholderia_phage	1.0e-06	38.9
WP_004152935.1\|4016234_4016906_-\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	3.2e-61	58.9
WP_004150992.1\|4016898_4017807_-\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	1.9e-109	68.9
WP_004150993.1\|4017793_4018156_-\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	8.4e-48	85.6
WP_004150994.1\|4018152_4018725_-\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	1.4e-76	70.8
WP_004150995.1\|4018819_4019686_+	hypothetical protein	NA	NA	NA	NA
WP_004150996.1\|4019708_4020155_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.5e-54	72.3
WP_004150997.1\|4020147_4020570_-\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	8.2e-63	83.2
WP_004150998.1\|4020665_4021094_-\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	7.1e-54	82.5
WP_004150999.1\|4021090_4021474_-	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	1.9e-18	45.4
WP_004151000.1\|4021478_4021988_-	lysozyme	E5G6N1	Salmonella_phage	1.6e-81	85.2
WP_004134639.1\|4021968_4022184_-	hypothetical protein	E5G6N0	Salmonella_phage	6.1e-30	88.7
WP_004151001.1\|4022187_4022391_-\|tail	tail protein X	E5G6M9	Salmonella_phage	9.8e-30	89.6
WP_004151002.1\|4022390_4022855_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	1.5e-73	85.7
WP_004134644.1\|4022950_4023604_-\|terminase	terminase endonuclease subunit	A0A1S6KZX1	Salmonella_phage	1.9e-90	80.0
WP_004151003.1\|4023607_4024660_-\|capsid	phage major capsid protein, P2 family	A0A1S6KZZ3	Salmonella_phage	6.8e-175	91.0
WP_004151004.1\|4024676_4025510_-\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	4.4e-100	77.6
WP_019405037.1\|4025650_4027414_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	91.8
WP_004151006.1\|4027413_4028457_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	3.1e-172	85.6
WP_024940854.1\|4028513_4028783_-	hypothetical protein	D2IZW1	Enterococcus_phage	1.4e-15	41.3
WP_004151007.1\|4029304_4030306_+	hypothetical protein	NA	NA	NA	NA
WP_004151008.1\|4030305_4031385_+	hypothetical protein	NA	NA	NA	NA
WP_004151009.1\|4031371_4032055_+	hypothetical protein	NA	NA	NA	NA
WP_004151010.1\|4032150_4032384_-	DinI family protein	A0A0M4S6H1	Salmonella_phage	2.0e-34	96.1
WP_004151011.1\|4032395_4032584_-	hypothetical protein	A0A1S6L006	Salmonella_phage	2.2e-23	90.3
WP_004151012.1\|4032746_4035131_-	replication endonuclease	A0A1S6L028	Salmonella_phage	0.0e+00	87.9
WP_004151013.1\|4035127_4035979_-	DNA adenine methylase	A0A1S6L011	Salmonella_phage	2.2e-115	75.4
WP_004151014.1\|4035975_4036203_-	TraR/DksA family transcriptional regulator	A0A1S6L007	Salmonella_phage	5.1e-35	92.0
WP_004151016.1\|4036202_4036436_-	DUF2732 family protein	A0A1S6L021	Salmonella_phage	6.0e-31	90.9
WP_004144796.1\|4036503_4036842_-	DUF5347 domain-containing protein	A0A218M4I7	Erwinia_phage	6.2e-29	58.0
WP_004151017.1\|4036805_4037006_-	DUF2724 domain-containing protein	A0A1S6L005	Salmonella_phage	4.5e-19	68.8
WP_004151018.1\|4037013_4037523_-	phage regulatory CII family protein	A0A1S6L008	Salmonella_phage	1.1e-77	85.8
WP_001397669.1\|4037555_4037798_-	hypothetical protein	A0A1S6KZZ6	Salmonella_phage	4.0e-38	98.8
WP_004151019.1\|4037920_4038550_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.4e-61	54.5
WP_004151020.1\|4038552_4039578_+\|integrase	site-specific integrase	A0A1S6L016	Salmonella_phage	1.5e-190	93.8
4041239:4041285	attR	NA	NA	NA	NA

DBSCAN-SWA_12

4758735 : 4807578

uncultured_Caudovirales_phage(66.67%)

terminase,protease,head,capsid,portal,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002918465.1\|4758735_4759230_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.5e-26	54.8
WP_002918467.1\|4759233_4759872_-	stringent starvation protein A	NA	NA	NA	NA
WP_000829818.1\|4760183_4760576_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_002918559.1\|4760591_4761020_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_004144945.1\|4761285_4762413_-	cell division protein ZapE	NA	NA	NA	NA
WP_002918565.1\|4762603_4763002_+	DUF1043 family protein	NA	NA	NA	NA
WP_002918566.1\|4763175_4764543_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	6.0e-22	25.3
WP_002918568.1\|4764630_4765689_+	outer membrane-stress sensor serine endopeptidase DegS	NA	NA	NA	NA
WP_002918570.1\|4765825_4766764_-	malate dehydrogenase	NA	NA	NA	NA
WP_002918625.1\|4767178_4767649_+	transcriptional regulator ArgR	NA	NA	NA	NA
WP_002918626.1\|4768024_4768288_+	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_002918627.1\|4768386_4768653_+	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_002918629.1\|4768703_4768979_-	hypothetical protein	NA	NA	NA	NA
WP_002918632.1\|4769058_4771026_-	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_002918639.1\|4771031_4771964_-	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_002918640.1\|4771971_4772175_-	AaeX family protein	NA	NA	NA	NA
WP_002918641.1\|4772306_4773236_+	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
WP_002918642.1\|4773271_4774717_-\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_004150952.1\|4774805_4778603_-	AsmA2 domain-containing protein	NA	NA	NA	NA
WP_002918644.1\|4778640_4780110_-	ribonuclease G	NA	NA	NA	NA
WP_002918646.1\|4780112_4780694_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_002918648.1\|4780701_4781190_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004149974.1\|4781189_4782182_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_002918653.1\|4782252_4783296_-	rod shape-determining protein	F2Y0P3	Organic_Lake_phycodnavirus	6.7e-05	22.3
WP_002918686.1\|4783601_4785542_-	RNase E specificity factor CsrD	NA	NA	NA	NA
WP_002918687.1\|4785621_4785813_-	hypothetical protein	NA	NA	NA	NA
WP_002918688.1\|4786041_4787043_+	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_002918689.1\|4787042_4787651_+	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_002918732.1\|4787874_4788327_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_002918736.1\|4788349_4788817_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_002918738.1\|4788827_4790177_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_002918740.1\|4790287_4790530_+	YhdT family protein	NA	NA	NA	NA
WP_002918742.1\|4790519_4791971_+	sodium/pantothenate symporter	NA	NA	NA	NA
WP_002918745.1\|4791982_4792864_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_004144972.1\|4793221_4794187_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_000462905.1\|4794211_4794508_+	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_004150954.1\|4794661_4794853_-	hypothetical protein	NA	NA	NA	NA
WP_004150955.1\|4794855_4796517_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	0.0e+00	98.0
WP_000113647.1\|4796500_4796857_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	5.5e-60	99.2
WP_004150959.1\|4797132_4797576_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	2.8e-77	91.8
WP_001547824.1\|4797575_4797875_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	3.4e-39	80.8
WP_004150961.1\|4797871_4798207_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	3.7e-26	57.8
WP_004150962.1\|4798203_4799445_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	1.0e-230	96.5
WP_001547826.1\|4799446_4800007_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.2e-98	95.7
WP_001549743.1\|4800058_4801225_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	9.8e-207	95.9
WP_004150963.1\|4801488_4802001_+	hypothetical protein	NA	NA	NA	NA
WP_004150964.1\|4802049_4802385_-	hypothetical protein	NA	NA	NA	NA
WP_004150965.1\|4802727_4804863_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	3.4e-205	62.4
WP_001549749.1\|4804862_4805228_-	hypothetical protein	NA	NA	NA	NA
WP_004150966.1\|4805224_4805593_-	hypothetical protein	A0A2H4JCX7	uncultured_Caudovirales_phage	3.7e-51	81.1
WP_004150967.1\|4805589_4805904_-	hypothetical protein	NA	NA	NA	NA
WP_001549752.1\|4805896_4806085_-	hypothetical protein	NA	NA	NA	NA
WP_106918304.1\|4806077_4806347_-	host cell division inhibitor Icd-like protein	A0A2H4JGW3	uncultured_Caudovirales_phage	2.4e-44	94.4
WP_004150969.1\|4806798_4807578_-	hypothetical protein	Q8HA02	Enterobacteria_phage	6.2e-40	51.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP021753

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021753_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021753_1

112588-112756

Orphan

Consensus_repeat	Method
ATAATTAAATCATGATTTAATG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP021753_1

>merge|NZ_CP021753|1|112588-112756|PILER-CR
ATAATTAAATCATGATTTCATTTATTTTTATGCTATTGTAATTTAAGTCATTATTGTTTTGCATGTTTTACTGAAATCATTAAATCATGATTTAATGTTGTTCCTTTACCTCAGCTATGTCATAGTTAGCTTAGTTGTAGAACTTGATAATGAAATCATGATTTAATGA

>NZ_CP021753|1|1|112588-112756|PILER-CR
ATAATTAAATCATGATTTCATTT	ATTTTTATGCTATTGTAATTTAAGTCATTATTGTTTTGCATGTTTTACTGAAATCAT
TAAATCATGATTTAATGTTGTTC	CTTTACCTCAGCTATGTCATAGTTAGCTTAGTTGTAGAACTTGATAATG
AAATCATGATTTAATGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021753.1\|WP_020314646.1\|109581_110193_+\|DUF2913-family-protein	unknown	unknown	gnl\|CDD\|371392
NZ_CP021753.1\|WP_020314652.1\|113840_115115_-\|Y-family-DNA-polymerase	unknown	unknown	gnl\|CDD\|179607
NZ_CP021753.1\|WP_020314635.1\|115572_115818_-\|DinI-like-family-protein	unknown	unknown	gnl\|CDD\|368780
NZ_CP021753.1\|WP_000235177.1\|102310_102709_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NZ_CP021753.1\|WP_020314642.1\|111549_112170_-\|resolvase	unknown	unknown	gnl\|CDD\|239736
NZ_CP021753.1\|WP_022644720.1\|104441_107480_+\|Tn3-family-transposase	unknown	unknown	gnl\|CDD\|376561
NZ_CP021753.1\|WP_009652884.1\|102774_103611_+\|S-formylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|131868
NZ_CP021753.1\|WP_020314634.1\|113438_113666_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021753.1\|WP_000470624.1\|103638_104274_-\|serine-recombinase	unknown	unknown	gnl\|CDD\|239736
NZ_CP021753.1\|WP_022644719.1\|111263_111530_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021753.1\|WP_046960466.1\|115126_115576_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl\|CDD\|182350
NZ_CP021753.1\|WP_020314648.1\|108985_109264_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021753.1\|WP_022644718.1\|112767_113394_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|349760
NZ_CP021753.1\|WP_001567660.1\|107503_108526_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NZ_CP021753.1\|WP_020314639.1\|110189_111143_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|227751

Protein	Function_ID	Function_description	E-value
NZ_CP021753.1\|WP_020314646.1\|109581_110193_+\|DUF2913-family-protein	gnl\|CDD\|371392	pfam11140, DUF2913, Protein of unknown function (DUF2913). This family of proteins with unknown function appear to be restricted to Gammaproteobacteria.	4.82332e-14
NZ_CP021753.1\|WP_022644720.1\|104441_107480_+\|Tn3-family-transposase	gnl\|CDD\|376561	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain. This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.	0
NZ_CP021753.1\|WP_020314652.1\|113840_115115_-\|Y-family-DNA-polymerase	gnl\|CDD\|179607	PRK03609, umuC, translesion error-prone DNA polymerase V subunit UmuC.	0
NZ_CP021753.1\|WP_020314635.1\|115572_115818_-\|DinI-like-family-protein	gnl\|CDD\|368780	pfam06183, DinI, DinI-like family. This family of short proteins includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co- protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity. The structure of DinI is known.	2.94757e-08
NZ_CP021753.1\|WP_000235177.1\|102310_102709_+\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.83252e-43
NZ_CP021753.1\|WP_020314642.1\|111549_112170_-\|resolvase	gnl\|CDD\|239736	cd03767, SR_Res_par, Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subgroup is composed of proteins similar to the E. coli resolvase found in the par region of the RP4 plasmid, which encodes a highly efficient partitioning system. This protein is part of a complex stabilization system involved in the resolution of plasmid dimers during cell division. Similar to Tn3 and other resolvases, members of this family may contain a C-terminal DNA binding domain.	1.67235e-69
NZ_CP021753.1\|WP_020314639.1\|110189_111143_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|227751	COG5464, COG5464, Uncharacterized conserved protein [Function unknown].	2.6724e-120
NZ_CP021753.1\|WP_009652884.1\|102774_103611_+\|S-formylglutathione-hydrolase	gnl\|CDD\|131868	TIGR02821, S-formylglutathione_hydrolase, S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well. [Cellular processes, Detoxification].	2.23439e-133
NZ_CP021753.1\|WP_000470624.1\|103638_104274_-\|serine-recombinase	gnl\|CDD\|239736	cd03767, SR_Res_par, Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subgroup is composed of proteins similar to the E. coli resolvase found in the par region of the RP4 plasmid, which encodes a highly efficient partitioning system. This protein is part of a complex stabilization system involved in the resolution of plasmid dimers during cell division. Similar to Tn3 and other resolvases, members of this family may contain a C-terminal DNA binding domain.	1.74126e-75
NZ_CP021753.1\|WP_046960466.1\|115126_115576_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl\|CDD\|182350	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit.	1.88389e-55
NZ_CP021753.1\|WP_022644718.1\|112767_113394_+\|ParA-family-protein	gnl\|CDD\|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	1.14227e-14
NZ_CP021753.1\|WP_001567660.1\|107503_108526_+\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.61883e-54

>NZ_CP021753.1|WP_020314642.1|111549_112170_-|resolvase
MFVFGYLRASTSEQDASRAKNVLKAFANQHGHRIAGWYIDNVSGTTMNRPELIRLLGDAEPGDVILIEQVDRLTRLDDAGWETLRKQITDKQLAIVSLDLPTSYLALSSTVSDDFTRSMLKAVNGMMLDMLAAIARKDYEDRRRRQSEGISKAKAEGKYRGRVADAQKHELIRTLRLVNGKSLRETARLAGVSKMTVIRVCSSADK
>NZ_CP021753.1|WP_022644719.1|111263_111530_-|hypothetical-protein
MKTKKIPLVIYTVIVAGLTILGTRLYDSVSDTTDPAIANGPFWAGLCVKTDSKDGMNELICSNIRIFVKAEDYDRSVRKRELSGILND
>NZ_CP021753.1|WP_020314639.1|110189_111143_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MKKKNSTPTPHDATFRQFLTQPDIARDFMELHLPAELQAICDLSTLKLESGSFIEDDLRQYFSDVLYSLKTTAGDGYVHVLIEHQSSPDKHMAFRLIRYAVAAMQRHLEAGHKKLPLVIPVLFYTGKRSPYPYSTRWLDEFDDPILAGTLYSSAFPLVDVTVIPDDEIAGHRSMAALTLLQKHIHQRDLAELVDRLAPILLAGYLSSSQVVSLVHYIVQAGETSDAEAFVRELAQRVPQHGDALMTIAQQLEQKGIEKGIQQGIEQGIQLGEQRGIEKGEREATLKIARTMLQNGIDRNTVMKVTGLTEEDLAQIRH
>NZ_CP021753.1|WP_020314646.1|109581_110193_+|DUF2913-family-protein
MALTHKTGHLAWCALVALALARKEQGELSPAQENLFLTRWLAAALKQRRFSRDVAQDIGWLLNQGRLLGVRAKLADKLDYVWRSCSGELTEQNDMFRLTYALETAKDMGWNYRVMSDREWAGRYALVLNPGVNGVYLLRTNLDAAFDDNGQQTNPLTARLTGSVAGVMKLLNRCGWQAEPESGASLPHQYSLMAGQGVPGKGD
>NZ_CP021753.1|WP_020314648.1|108985_109264_+|hypothetical-protein
MRVAEHIILDALTRGGCIKTFWRISSRQAAESSARIPEGYILESPGEREDIVLSHADFHALEKQLEQKETWEQVVGVTCFGGVTWQLRAGSV
>NZ_CP021753.1|WP_001567660.1|107503_108526_+|IS110-family-transposase
MTITTVGIDLAKNVFAVHCVDQNGKTVLVKSRVTRAALPGLIAGLPPCVIGMEACSGAHYWARLFRQYGHEPRLMAAKFVSPYRMAGKSGKNDAADAQAICEAVRRPHMRFVPVKDESQQAMQCLHRTRQGFIEEKTATYNRLRGLISEFGVIAPQSTDALRHIVFEQKNSLPLQVQQCVDDLLEHVARIEDNIAEYDRILSRMAKTDHRSQRLMELKGVGPTTACALVASIGNAHDFKNGRQLAAWLGLTPSQYSSGGKSKLGRITKAGDSYLRTLLVQGARSVLIGAEKRTDLFSRWVCSLVERRGYWRAVVAIAAKNARLCWASLHYGDDFRLYSAS
>NZ_CP021753.1|WP_022644720.1|104441_107480_+|Tn3-family-transposase
MARRQILSLSERESLLALPDEELTLTRMAYFSEHDLALISAHRKPASRFGFAVLLCYLKNVGFTPDKKIPPSDALLKHIASRLKLTGDLWPAYLSGRETTRREHLTELYRYLGLKAFTGKIQQDCITHLLPMATRTDKGILLAEELLVWLRQNNVIIPSIDVVERSCAEAMAGGDKIVFQTLNAPLTPAHRDALDCLLESSDNQSSRLTWLLQPPGKINGKNVLQHLDRLSSIESLALPEGIDRTIHQNRLLKLAREGRKMSSRDLTRFSAARRHAILVCVLEEARATLTDEVIELHERMLNSLFSKAKRTQAERLQQTGKLIQSKLRQYINVGQALSDARDSGGDPWLAIENILPWPEFVASLEETRHLARKNNFDPLHIITEKYSTLRKYAPRMLSALQLIATPAAQPLADALVVIKDMYRKQSRKVPATAPLEFVPESWRKVVITPAGIDRQYYEFCALSELKGALRSGDIWVKGSRRYKNFDDYLIPEKDFDKLTPALPLPVSADYHEYITSRMTLLQSRLEEVNAMAALGELPDVEISYRGVKVSPLDNSVPVQVSPLAELVYSMLPRPKITEILDEVNSWTTFTRHFSHIKTDITRPDIRLLLTTILADGINLGLTKMAEACPGSTKSSLEDIQAWYIRDETYSAALAELVNAQGKRPLAAFWGDGTTSSSDGQNFRTGRSGRYAGQVNPKYGQEPGRQFYTHISDQYSPFYTCIISRVRDSTHVLDGLLYHESDLEIREHYTDTAGFTDHVFALMHLLGFAFCPRIRDLHDKKLFIKGKAGQYPALQSLISTTSLNLKEIEIHWREVLRLATSIKQGTVTASLMLKKLASYPKQNGLAKALREIGRIERTLFMLDWFRDPALRRRVQAGLNKGEARNALARAVFMHRLGEIRDRKPENQSYRASGLTLLTAAISLWNTVYMERAVDALKRKGVKINEQLLSHLSPLGWEHINLTGDYIWKSNRIPSAGKFRRLRPAKLGRSKNNLNEWKGLPLIMRLINSCAIMG
>NZ_CP021753.1|WP_000470624.1|103638_104274_-|serine-recombinase
MFIRAYLRASTEDQFADRAKEMLEQFVQERGHKIASYYRENISGTKLDRPELGRLLMDSHRNDILLVEQIDRLTRLSNSDWMTLKKQIEQHELRIVSLDVPTSWQALSDKDPSQADPITRAVITAINNMLIDLMASMSHKDWLSRRHRQKQGIERAHTLGKYRGKQADQERHKKVLYYRQVKKLSIRETAEATGYSTSQVCRIQALFRPEN
>NZ_CP021753.1|WP_009652884.1|102774_103611_+|S-formylglutathione-hydrolase
MELIEQHASAGGWQNVYRHNSQTLNCGMNFGVYLPPKAATEKLPVLYWLSGLTCTEQNFITKSGMQHYAARNNIIVVVPDTSPRGEHVADADSYDLGQGAGFYLNATEHPWNTHYRMYDYILHELPDVVMEHLPVTSRKSISGHSMGGLGALVLSLRNPDEYVSVSAFSPIVSPSQVPWGQQAFTAYLGENKKTWEHYDPVSLILQGAKLPEIFIDQGLSDAFYEDQLRTKSLERVCNEMNINTSFRYHTGYDHSYYFISSFIGEHIAYHANRLRLSA
>NZ_CP021753.1|WP_000235177.1|102310_102709_+|VOC-family-protein
MATPVISGNDVFSHVFIGASDVEKSADFYDAVLGTLGINNLGPFGNGWVLYGREKPAFIIAHPGNGEAPSANGVTVGFAAASPEEVDAFHAAGLAAGGKDEGQPGPRSHLPGAYAAYLRDPAGNKITAYTFI
>NZ_CP021753.1|WP_022644718.1|112767_113394_+|ParA-family-protein
MGKVISIVGQKGGGSKSTEARTLAVGFSEAGWKTHLADIDTKQQTSLKWTERREKSGLSPIDCALYRRVETAVRMKDSCHLLIIDGRPAAETTSLDVADESDLVIITTGTTIDDLEPSLELARELIKKGIDKSKIVFIVSKSPSQSQGEKAQETIKAWGYKVINTVIPFKTSYGEALDTGRALHETPFKSLNETAKQMIEEIHDIINS
>NZ_CP021753.1|WP_020314634.1|113438_113666_+|hypothetical-protein
MKGPGKSIKIEPPKEDEPTLDVTGKGAVPDSAVKPIQIKVPVSKHKEMKAYAAEQGISMTDMLLAGYDMYRNKMK
>NZ_CP021753.1|WP_020314652.1|113840_115115_-|Y-family-DNA-polymerase
MFALADVNSFYASCEKVFRPDLRDRPVIVLSNNDGCVIARSREARAIGIPMGAPWFKVKGLAEKHNVAVFSSNYSLYHSMSERVMRCLEALAPRVEQYSIDEMFLDVAGIDNCVDFEDFGRQLREYVHRHTALTIGVGMGPSKTLAKSAQWASKEWPQFGGVLALTPDNPRRTEKLLSLQPVEEIWGVGRRISKKLNTMGITTALQLARANPAFIRKNFNVVLERTVRELNGESCISLEEAPPPKQQIVCSRSFGERITEYDAMRQAVCQYAERAAEKLRSERQYCRHIAVFVKTSPFAVKEPYYGNMASESLPFPSRDSRDIIAAAVRALGRIWVPEHRYAKAGVMLNDFTPAGVSQLSLFDDVQPRANSEALMNVVDGINHSGLGKVWFAGRGIAPDWQMKRDLLSPAYTTRWADIPSARLC
>NZ_CP021753.1|WP_046960466.1|115126_115576_-|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MSRREPLFDPEAVFTLPATPSSLQLPLFADACAAGFPSPAGDYVEQELDLNSLCIRHPAATYFLRASGESMKDLGLYDGDILVVDRSETAVDGDVVIAEVDGGFTVKRLRLHPRPALEPMNPAYPTLWPEELTLFGVVMHFIHRTRARL
>NZ_CP021753.1|WP_020314635.1|115572_115818_-|DinI-like-family-protein
MLQISVRFSPEQVKAMRSGTFAALQQEIERRLTPRYPQLWLNIGKSSQTALDVSGARSDKEKSDIMNTLEAIWQDDTWLPE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP021753	Klebsiella pneumoniae strain AR_0113 plasmid unitig_2, complete sequence	112606-112662	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	CP052165	Klebsiella pneumoniae strain F16KP0082 plasmid pF16KP0082-3, complete sequence	15773-15829	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	CP052160	Klebsiella pneumoniae strain F16KP0084 plasmid pF16KP0084-2, complete sequence	52062-52118	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	CP052145	Klebsiella pneumoniae strain F17KP0012 plasmid pF17KP0012-2, complete sequence	16181-16237	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP008791	Klebsiella oxytoca KONIH1 plasmid pKPC-727, complete sequence	176746-176802	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP025040	Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_3, complete sequence	79461-79517	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP022275	Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence	61191-61247	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	MN891677	Klebsiella pneumoniae strain ZZ41 plasmid pZZ41-KPC, complete sequence	51326-51382	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	MN891679	Klebsiella pneumoniae strain ZZ40 plasmid pZZ40-KPC, complete sequence	32331-32387	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP027614	Klebsiella pneumoniae subsp. ozaenae strain AR_0096 plasmid unnamed2, complete sequence	13684-13740	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP022349	Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence	43005-43061	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	KY940546	Klebsiella pneumoniae plasmid pUCLA3, complete sequence	29736-29792	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP021545	Klebsiella pneumoniae strain AR_0112 plasmid tig00000001, complete sequence	79808-79864	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP006922	Klebsiella pneumoniae 30684/NJST258_2 plasmid pNJST258C1, complete sequence	8165-8221	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP020064	Klebsiella pneumoniae strain AR_0117 plasmid unitig_3, complete sequence	75854-75910	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP038275	Raoultella ornithinolytica strain WLK218 plasmid pWLK-101716, complete sequence	99886-99942	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP021857	Klebsiella pneumoniae strain AR_0125 plasmid tig00000002_pilon, complete sequence	68227-68283	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	CP052205	Klebsiella pneumoniae strain F16KP0002 plasmid pF16KP0002-2, complete sequence	105904-105960	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP023186	Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence	22497-22553	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_CP026717	Klebsiella oxytoca strain AR_0028 plasmid unitig_2_pilon, complete sequence	64587-64643	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	NZ_MF788069	Raoultella ornithinolytica strain 23141 plasmid p23141-1, complete sequence	43995-44051	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	MT108213	Klebsiella pneumoniae strain ZZ100 plasmid pZZ100-KPC, complete sequence	30012-30068	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP021753	Klebsiella pneumoniae strain AR_0113 plasmid unitig_2, complete sequence	112685-112733	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	CP052165	Klebsiella pneumoniae strain F16KP0082 plasmid pF16KP0082-3, complete sequence	15702-15750	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	CP052160	Klebsiella pneumoniae strain F16KP0084 plasmid pF16KP0084-2, complete sequence	52141-52189	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	CP052145	Klebsiella pneumoniae strain F17KP0012 plasmid pF17KP0012-2, complete sequence	16260-16308	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP008791	Klebsiella oxytoca KONIH1 plasmid pKPC-727, complete sequence	176825-176873	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP025040	Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_3, complete sequence	79540-79588	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP022275	Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence	61120-61168	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	MN891677	Klebsiella pneumoniae strain ZZ41 plasmid pZZ41-KPC, complete sequence	51405-51453	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	MN891679	Klebsiella pneumoniae strain ZZ40 plasmid pZZ40-KPC, complete sequence	32260-32308	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP017590	Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ09, complete sequence	107476-107524	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP027614	Klebsiella pneumoniae subsp. ozaenae strain AR_0096 plasmid unnamed2, complete sequence	13763-13811	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP022349	Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence	43084-43132	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	KY940546	Klebsiella pneumoniae plasmid pUCLA3, complete sequence	29815-29863	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP021545	Klebsiella pneumoniae strain AR_0112 plasmid tig00000001, complete sequence	79887-79935	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP006922	Klebsiella pneumoniae 30684/NJST258_2 plasmid pNJST258C1, complete sequence	8244-8292	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP020064	Klebsiella pneumoniae strain AR_0117 plasmid unitig_3, complete sequence	75783-75831	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP038275	Raoultella ornithinolytica strain WLK218 plasmid pWLK-101716, complete sequence	99815-99863	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	CP050170	Klebsiella pneumoniae plasmid Carbapenemase(KPC-2)_IncFII, complete sequence	27143-27191	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP021857	Klebsiella pneumoniae strain AR_0125 plasmid tig00000002_pilon, complete sequence	68306-68354	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	CP052205	Klebsiella pneumoniae strain F16KP0002 plasmid pF16KP0002-2, complete sequence	105983-106031	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP023186	Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence	22426-22474	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_CP026717	Klebsiella oxytoca strain AR_0028 plasmid unitig_2_pilon, complete sequence	64516-64564	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	NZ_MF788069	Raoultella ornithinolytica strain 23141 plasmid p23141-1, complete sequence	44074-44122	0	1.0
NZ_CP021753_1	1.2\|112691\|49\|NZ_CP021753\|PILER-CR	112691-112739	49	MT108213	Klebsiella pneumoniae strain ZZ100 plasmid pZZ100-KPC, complete sequence	29941-29989	0	1.0
NZ_CP021753_1	1.1\|112611\|57\|NZ_CP021753\|PILER-CR	112611-112667	57	CP050170	Klebsiella pneumoniae plasmid Carbapenemase(KPC-2)_IncFII, complete sequence	27214-27270	1	0.982

1. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP021753 (Klebsiella pneumoniae strain AR_0113 plasmid unitig_2, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

2. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to CP052165 (Klebsiella pneumoniae strain F16KP0082 plasmid pF16KP0082-3, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

3. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to CP052160 (Klebsiella pneumoniae strain F16KP0084 plasmid pF16KP0084-2, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

4. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to CP052145 (Klebsiella pneumoniae strain F17KP0012 plasmid pF17KP0012-2, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

5. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP008791 (Klebsiella oxytoca KONIH1 plasmid pKPC-727, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

6. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP025040 (Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_3, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

7. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP022275 (Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

8. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to MN891677 (Klebsiella pneumoniae strain ZZ41 plasmid pZZ41-KPC, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

9. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to MN891679 (Klebsiella pneumoniae strain ZZ40 plasmid pZZ40-KPC, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

10. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP027614 (Klebsiella pneumoniae subsp. ozaenae strain AR_0096 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

11. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP022349 (Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

12. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to KY940546 (Klebsiella pneumoniae plasmid pUCLA3, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

13. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP021545 (Klebsiella pneumoniae strain AR_0112 plasmid tig00000001, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

14. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP006922 (Klebsiella pneumoniae 30684/NJST258_2 plasmid pNJST258C1, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

15. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP020064 (Klebsiella pneumoniae strain AR_0117 plasmid unitig_3, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

16. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP038275 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-101716, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

17. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP021857 (Klebsiella pneumoniae strain AR_0125 plasmid tig00000002_pilon, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

18. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to CP052205 (Klebsiella pneumoniae strain F16KP0002 plasmid pF16KP0002-2, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

19. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP023186 (Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

20. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_CP026717 (Klebsiella oxytoca strain AR_0028 plasmid unitig_2_pilon, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

21. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to NZ_MF788069 (Raoultella ornithinolytica strain 23141 plasmid p23141-1, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

22. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to MT108213 (Klebsiella pneumoniae strain ZZ100 plasmid pZZ100-KPC, complete sequence) position: , mismatch: 0, identity: 1.0

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
*********************************************************

23. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP021753 (Klebsiella pneumoniae strain AR_0113 plasmid unitig_2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

24. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to CP052165 (Klebsiella pneumoniae strain F16KP0082 plasmid pF16KP0082-3, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

25. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to CP052160 (Klebsiella pneumoniae strain F16KP0084 plasmid pF16KP0084-2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

26. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to CP052145 (Klebsiella pneumoniae strain F17KP0012 plasmid pF17KP0012-2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

27. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP008791 (Klebsiella oxytoca KONIH1 plasmid pKPC-727, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

28. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP025040 (Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_3, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

29. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP022275 (Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

30. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to MN891677 (Klebsiella pneumoniae strain ZZ41 plasmid pZZ41-KPC, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

31. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to MN891679 (Klebsiella pneumoniae strain ZZ40 plasmid pZZ40-KPC, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

32. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP017590 (Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ09, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

33. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP027614 (Klebsiella pneumoniae subsp. ozaenae strain AR_0096 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

34. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP022349 (Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

35. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to KY940546 (Klebsiella pneumoniae plasmid pUCLA3, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

36. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP021545 (Klebsiella pneumoniae strain AR_0112 plasmid tig00000001, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

37. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP006922 (Klebsiella pneumoniae 30684/NJST258_2 plasmid pNJST258C1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

38. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP020064 (Klebsiella pneumoniae strain AR_0117 plasmid unitig_3, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

39. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP038275 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-101716, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

40. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to CP050170 (Klebsiella pneumoniae plasmid Carbapenemase(KPC-2)_IncFII, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

41. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP021857 (Klebsiella pneumoniae strain AR_0125 plasmid tig00000002_pilon, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

42. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to CP052205 (Klebsiella pneumoniae strain F16KP0002 plasmid pF16KP0002-2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

43. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP023186 (Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

44. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_CP026717 (Klebsiella oxytoca strain AR_0028 plasmid unitig_2_pilon, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

45. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to NZ_MF788069 (Raoultella ornithinolytica strain 23141 plasmid p23141-1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

46. spacer 1.2|112691|49|NZ_CP021753|PILER-CR matches to MT108213 (Klebsiella pneumoniae strain ZZ100 plasmid pZZ100-KPC, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	CRISPR spacer
ttgttcctttacctcagctatgtcatagttagcttagttgtagaacttg	Protospacer
*************************************************

47. spacer 1.1|112611|57|NZ_CP021753|PILER-CR matches to CP050170 (Klebsiella pneumoniae plasmid Carbapenemase(KPC-2)_IncFII, complete sequence) position: , mismatch: 1, identity: 0.982

catttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	CRISPR spacer
aatttatttttatgctattgtaatttaagtcattattgttttgcatgttttactgaa	Protospacer
 ********************************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

56544 : 93861

Salmonella_phage(28.57%)

integrase,transposase

attL 56374:56433|attR 92491:94178

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
56374:56433	attL	NA	NA	NA	NA
WP_000948429.1\|56544_57744_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000957857.1\|57753_57942_-	hypothetical protein	NA	NA	NA	NA
WP_000443938.1\|58981_60433_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_009309939.1\|60425_62468_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_022644729.1\|62654_68390_+	DUF4011 domain-containing protein	NA	NA	NA	NA
WP_020802676.1\|68851_71749_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	5.5e-182	37.8
WP_000509966.1\|71843_72449_+	DNA resolvase	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
WP_004194048.1\|73108_74290_+	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	1.9e-120	64.2
WP_000091613.1\|74716_75031_-	hypothetical protein	NA	NA	NA	NA
WP_000215515.1\|75285_75642_-	cupin domain-containing protein	NA	NA	NA	NA
WP_001293886.1\|75631_76033_-	DUF86 domain-containing protein	NA	NA	NA	NA
WP_001247892.1\|76029_76320_-	nucleotidyltransferase	NA	NA	NA	NA
WP_015065644.1\|76394_79361_+\|transposase	Tn3-like element ISPa38 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.2
WP_000427623.1\|79439_80444_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_004197809.1\|80625_80829_-	hypothetical protein	NA	NA	NA	NA
WP_004197808.1\|80842_81046_-	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_004197807.1\|81079_81448_-	hypothetical protein	NA	NA	NA	NA
WP_020802777.1\|81491_81986_-	hypothetical protein	NA	NA	NA	NA
WP_020317495.1\|82016_82592_-	hypothetical protein	NA	NA	NA	NA
WP_020804424.1\|82579_82849_-	hypothetical protein	NA	NA	NA	NA
WP_020315560.1\|83285_83975_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_004193995.1\|84006_84696_-	hypothetical protein	NA	NA	NA	NA
WP_001568025.1\|85248_85467_+	type II toxin-antitoxin system antitoxin CcdA	NA	NA	NA	NA
WP_001568026.1\|85468_85774_+	type II toxin-antitoxin system toxin CcdB	NA	NA	NA	NA
WP_025380813.1\|85978_86338_+	hypothetical protein	NA	NA	NA	NA
WP_022644730.1\|86364_86688_+	hypothetical protein	NA	NA	NA	NA
WP_020315256.1\|86684_87701_+	hypothetical protein	NA	NA	NA	NA
WP_004197635.1\|87898_88693_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.5e-52	88.7
WP_006788217.1\|89148_89328_-	hypothetical protein	NA	NA	NA	NA
WP_004197649.1\|89447_90074_-	ParA family plasmid-partitioning AAA ATPase	A0A222YXS3	Escherichia_phage	2.9e-40	43.6
WP_022644731.1\|90706_91582_-	RepB family plasmid replication initiator protein	Q71TL8	Escherichia_phage	1.9e-82	57.1
WP_000948429.1\|92661_93861_-\|transposase	IS91 family transposase	NA	NA	NA	NA
92491:94178	attR	NA	NA	NA	NA

DBSCAN-SWA_2

110189 : 115818

Aeromonas_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020314639.1\|110189_111143_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	9.5e-75	57.1
WP_022644719.1\|111263_111530_-	hypothetical protein	NA	NA	NA	NA
WP_020314642.1\|111549_112170_-	resolvase	A0A219Y912	Aeromonas_phage	1.0e-08	31.0
WP_022644718.1\|112767_113394_+	ParA family protein	A0A2H4EW66	Aeromonas_phage	4.5e-25	34.4
WP_020314634.1\|113438_113666_+	hypothetical protein	NA	NA	NA	NA
WP_020314652.1\|113840_115115_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	1.3e-148	60.7
WP_046960466.1\|115126_115576_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.3e-31	52.0
WP_020314635.1\|115572_115818_-	DinI-like family protein	Q7Y3V9	Yersinia_phage	1.1e-08	39.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP021756

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 13062

Escherichia_phage(50.0%)

transposase,lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000072676.1\|1759_2023_+	hypothetical protein	NA	NA	NA	NA
WP_001146176.1\|2012_2312_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000312627.1\|2373_2751_-	hypothetical protein	NA	NA	NA	NA
WP_000165971.1\|2819_2999_+	Rop family plasmid primer RNA-binding protein	NA	NA	NA	NA
WP_004153058.1\|3026_3557_-	hypothetical protein	NA	NA	NA	NA
WP_004152551.1\|3563_4295_-	hypothetical protein	NA	NA	NA	NA
WP_004178196.1\|4294_6259_-	TraM recognition domain-containing protein	NA	NA	NA	NA
WP_004152552.1\|7739_7889_-\|lysis	lysis protein	NA	NA	NA	NA
WP_004152553.1\|7973_8231_-	cloacin	NA	NA	NA	NA
WP_004178188.1\|8240_9926_-	cloacin	NA	NA	NA	NA
WP_001067855.1\|10661_11366_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_063840280.1\|11716_12271_-	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
WP_001217881.1\|12504_13062_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4

DBSCAN-SWA_2

19137 : 22207

Escherichia_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004199214.1\|19137_20163_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
WP_004152394.1\|20159_20939_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
WP_004152396.1\|21325_22207_+	carbapenem-hydrolyzing class A beta-lactamase KPC-3	A0A1B0VBP7	Salmonella_phage	2.8e-73	52.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP021755

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 3236

Enterobacteria_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217881.1\|835_1393_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
WP_063840280.1\|1626_2181_+	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
WP_001067855.1\|2531_3236_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

DBSCAN-SWA_2

9100 : 42257

Escherichia_phage(29.41%)

transposase,integrase

attL 2240:2299|attR 32887:33115

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2240:2299	attL	NA	NA	NA	NA
WP_000015958.1\|9100_9877_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	6.4e-53	92.9
WP_000764642.1\|9934_10192_-	hypothetical protein	NA	NA	NA	NA
WP_004118283.1\|10954_11821_+	replication initiation protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
WP_000339857.1\|11997_12267_-	hypothetical protein	NA	NA	NA	NA
WP_000368714.1\|12681_13887_+	ParA family protein	A0A077SL49	Escherichia_phage	2.4e-163	69.6
WP_006797589.1\|13883_14861_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	5.0e-87	54.1
WP_001754953.1\|14942_16214_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	5.4e-150	63.7
WP_000776034.1\|16213_16645_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.6e-29	53.3
WP_004152765.1\|17053_18538_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_001118624.1\|21152_22076_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	1.8e-171	96.4
WP_001039464.1\|22215_22602_-	hypothetical protein	NA	NA	NA	NA
WP_001138014.1\|23449_26416_-\|transposase	Tn3-like element TnAs1 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	100.0
WP_001161490.1\|26419_26980_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0
WP_000454193.1\|27155_27506_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_000845048.1\|27708_28722_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001456218.1\|28888_29731_+	alpha/beta fold putative hydrolase EstX	NA	NA	NA	NA
WP_000050382.1\|29826_30435_+	HAD-IB family hydrolase	NA	NA	NA	NA
WP_001261740.1\|30492_31284_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_000095725.1\|31545_32805_+	chloramphenicol efflux MFS transporter CmlA1	S4TR35	Salmonella_phage	4.8e-26	31.7
WP_001206316.1\|32897_33689_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
32887:33115	attR	NA	NA	NA	NA
WP_000800531.1\|33858_34191_+	quaternary ammonium compound efflux SMR transporter QacL	NA	NA	NA	NA
WP_000034420.1\|35370_36162_-	sulfonamide-resistant dihydropteroate synthase Sul3	A0A0B5J4J5	Pandoravirus	1.2e-14	26.5
WP_001354008.1\|36630_36876_-	hypothetical protein	NA	NA	NA	NA
WP_000612791.1\|36913_37777_-	SDR family oxidoreductase	W8CYX9	Bacillus_phage	2.5e-05	31.0
WP_011264039.1\|37922_38162_-	macrolide transporter	A0A2K5B2B5	Erysipelothrix_phage	9.5e-08	46.2
WP_001067858.1\|38234_38939_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_001199192.1\|39052_39829_+	aminoglycoside N-acetyltransferase AAC(3)-IV	NA	NA	NA	NA
WP_000742814.1\|40057_41083_+	aminoglycoside O-phosphotransferase APH(4)-Ia	NA	NA	NA	NA
WP_000602738.1\|41504_42257_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.4e-41	44.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage