CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP021844	Escherichia coli strain EC1515 chromosome, complete genome	12 crisprs	csa3,PD-DExK,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,c2c9_V-U4,DinG,WYL	10	6
NZ_CP021846	Escherichia coli strain EC1515 plasmid pEC1515-2, complete sequence	0 crisprs	RT,csa3	0	2
NZ_CP021847	Escherichia coli strain EC1515 plasmid pEC1515-3, complete sequence	0 crisprs	NA	0	1
NZ_CP021845	Escherichia coli strain EC1515 plasmid pEC1515-1, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

29563 : 80752

Escherichia_phage(25.0%)

integrase,transposase

attL 38696:38712|attR 78573:78589

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000608644.1\|29563_30826_+\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_015056382.1\|31149_32295_+	class C beta-lactamase CMY-4	NA	NA	NA	NA
WP_001221666.1\|32388_32922_+	lipocalin family protein	A0A1W6JNX6	Morganella_phage	6.1e-47	54.1
WP_000118520.1\|32918_33236_-	quaternary ammonium compound-resistance protein SugE	NA	NA	NA	NA
WP_011264049.1\|34520_35729_+	IncI1-type conjugal transfer protein TrbA	NA	NA	NA	NA
WP_011264050.1\|35747_36818_+	IncI1-type conjugal transfer protein TrbB	NA	NA	NA	NA
38696:38712	attL	NA	NA	NA	NA
WP_000422741.1\|38901_39327_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|39323_39674_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080193.1\|39704_41318_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.3e-182	63.6
WP_088172500.1\|41351_41642_+	conjugal transfer protein TrbC	NA	NA	NA	NA
WP_011264053.1\|41679_44379_-	IncI1-type relaxase NikB	NA	NA	NA	NA
WP_001283947.1\|44389_44722_-	IncI1-type relaxosome accessory protein NikA	NA	NA	NA	NA
WP_021529212.1\|44955_45291_+	hypothetical protein	NA	NA	NA	NA
WP_001599394.1\|45377_46226_-	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_000148285.1\|46805_47057_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000150314.1\|47087_47294_-	hypothetical protein	NA	NA	NA	NA
WP_011264057.1\|47355_48258_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	9.0e-67	53.8
WP_000833767.1\|48254_48644_-	hypothetical protein	NA	NA	NA	NA
WP_000804663.1\|48820_49087_-	hypothetical protein	NA	NA	NA	NA
WP_000218858.1\|49180_49615_-	hypothetical protein	NA	NA	NA	NA
WP_000117611.1\|50343_50844_-	antirestriction protein ArdA	G9FHQ1	Rhodococcus_virus	2.4e-05	27.3
WP_001579745.1\|51443_51902_-	hypothetical protein	A0A0N7KZV3	Escherichia_phage	9.0e-15	56.6
WP_001276270.1\|51898_52618_-	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_001387500.1\|52614_53049_-	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_001145485.1\|53103_55062_-	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	7.3e-21	29.4
WP_000006020.1\|55120_55354_-	DUF905 domain-containing protein	A0A096XUX0	Cronobacter_phage	1.7e-06	53.2
WP_001276107.1\|55411_55939_-	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	3.5e-47	73.5
WP_001434357.1\|56322_56637_-	hypothetical protein	NA	NA	NA	NA
WP_001027495.1\|56707_56899_-	hypothetical protein	NA	NA	NA	NA
WP_000271744.1\|56895_57318_-	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_077249901.1\|57364_57667_-	antirestriction protein	NA	NA	NA	NA
WP_000274500.1\|59023_59458_-	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_001104881.1\|59471_59693_-	hypothetical protein	NA	NA	NA	NA
WP_000086147.1\|59693_60377_-	DNA methylase	A0A2I7RE86	Vibrio_phage	1.1e-29	36.4
WP_072748701.1\|60761_61664_-	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_000618110.1\|62081_62330_+	protein ImpC	Q2A098	Sodalis_phage	1.9e-14	48.0
WP_000109071.1\|62326_62764_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.3e-26	48.4
WP_000457523.1\|62763_64035_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	1.9e-142	60.5
WP_000340829.1\|64039_64432_-	hypothetical protein	NA	NA	NA	NA
WP_001103690.1\|64436_65408_-	hypothetical protein	A0A222YXF2	Escherichia_phage	7.4e-67	42.9
WP_000633913.1\|65636_66281_+	AAA family ATPase	A0A222YXS3	Escherichia_phage	1.9e-39	43.0
WP_000239529.1\|66274_66550_+	hypothetical protein	NA	NA	NA	NA
WP_001372173.1\|66687_67470_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.4e-52	92.0
WP_000715519.1\|67537_68146_-	hypothetical protein	NA	NA	NA	NA
WP_088172499.1\|68215_68566_-	hypothetical protein	NA	NA	NA	NA
WP_000139427.1\|69136_69718_+	hypothetical protein	NA	NA	NA	NA
WP_000628093.1\|69897_70233_+	hypothetical protein	NA	NA	NA	NA
WP_000074712.1\|70220_70868_+	hypothetical protein	NA	NA	NA	NA
WP_000642771.1\|71038_71323_-	hypothetical protein	NA	NA	NA	NA
WP_000545983.1\|71342_72476_-	hypothetical protein	NA	NA	NA	NA
WP_157698278.1\|72937_73333_+	hypothetical protein	NA	NA	NA	NA
WP_001067858.1\|73366_74071_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_072257968.1\|74162_74858_+	aminoglycoside 3-N-acetyltransferase	NA	NA	NA	NA
WP_000587837.1\|74870_75413_+	AAA family ATPase	NA	NA	NA	NA
WP_000951934.1\|75894_76086_-	hypothetical protein	NA	NA	NA	NA
WP_001330846.1\|76091_76337_+	hypothetical protein	NA	NA	NA	NA
WP_000080860.1\|76387_77524_+	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_001067858.1\|80047_80752_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
78573:78589	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP021844

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021844_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_1

893991-894110

Orphan

Consensus_repeat	Method
CCGCATCCGGCAATCAACGTCTGATGCGACGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_1

>merge|NZ_CP021844|1|893991-894110|CRISPRCasFinder
CCGCATCCGGCAATCAACGTCTGATGCGACGCTAGCGTGTCTTATCAGACCTACAACAGCTGCCACATGTCGGCTGAGGTGCTCACGCCGCATCCGGCAATCAACGTCTGATGCGACGCT

>NZ_CP021844|1|1|893991-894110|CRISPRCasFinder
CCGCATCCGGCAATCAACGTCTGATGCGACGCT	AGCGTGTCTTATCAGACCTACAACAGCTGCCACATGTCGGCTGAGGTGCTCACG
CCGCATCCGGCAATCAACGTCTGATGCGACGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_000239959.1\|894188_895325_-\|radical-SAM-family-heme-chaperone-HemW	unknown	unknown	gnl\|CDD\|235550
NZ_CP021844.1\|WP_000091700.1\|888135_888411_-\|oxidative-damage-protection-protein	unknown	unknown	gnl\|CDD\|180059
NZ_CP021844.1\|WP_000017103.1\|898675_899092_-\|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl\|CDD\|234639
NZ_CP021844.1\|WP_001222509.1\|900726_901458_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|272873
NZ_CP021844.1\|WP_001277222.1\|895918_896209_-\|YggU-family-protein	unknown	unknown	gnl\|CDD\|179931
NZ_CP021844.1\|WP_021577908.1\|883348_885484_+\|ornithine-decarboxylase	unknown	unknown	gnl\|CDD\|237434
NZ_CP021844.1\|WP_000593273.1\|899763_900714_-\|glutathione-synthase	unknown	unknown	gnl\|CDD\|235371
NZ_CP021844.1\|WP_021577907.1\|888438_889491_-\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|182805
NZ_CP021844.1\|WP_000760323.1\|886991_888071_-\|membrane-bound-lytic-murein-transglycosylase-MltC	unknown	unknown	gnl\|CDD\|183271
NZ_CP021844.1\|WP_000394107.1\|891775_892822_+\|L-asparaginase-2	unknown	unknown	gnl\|CDD\|182958
NZ_CP021844.1\|WP_000997795.1\|896789_897494_-\|pyridoxal-phosphate-homeostasis-protein	unknown	unknown	gnl\|CDD\|143497
NZ_CP021844.1\|WP_000745237.1\|892938_893946_+\|DUF1202-family-protein	unknown	unknown	gnl\|CDD\|284194
NZ_CP021844.1\|WP_000786911.1\|889651_890371_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP021844.1\|WP_001053178.1\|899091_899655_-\|YqgE/AlgH-family-protein	unknown	unknown	gnl\|CDD\|234694
NZ_CP021844.1\|WP_000984796.1\|890880_891600_+\|DUF2884-domain-containing-protein	unknown	unknown	gnl\|CDD\|182597
NZ_CP021844.1\|WP_021577906.1\|897511_898492_+\|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl\|CDD\|225364
NZ_CP021844.1\|WP_001107564.1\|890370_890697_+\|YggL-family-protein	unknown	unknown	gnl\|CDD\|183281
NZ_CP021844.1\|WP_001174750.1\|895317_895911_-\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP021844.1\|WP_001049791.1\|885533_886790_-\|nucleoside-permease	unknown	unknown	gnl\|CDD\|129967
NZ_CP021844.1\|WP_001094831.1\|896205_896772_-\|osmotic-shock-tolerance-protein-YggT	unknown	unknown	gnl\|CDD\|376765

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_000239959.1\|894188_895325_-\|radical-SAM-family-heme-chaperone-HemW	gnl\|CDD\|235550	PRK05660, PRK05660, radical SAM family heme chaperone HemW.	0
NZ_CP021844.1\|WP_000091700.1\|888135_888411_-\|oxidative-damage-protection-protein	gnl\|CDD\|180059	PRK05408, PRK05408, oxidative damage protection protein; Provisional.	3.17656e-56
NZ_CP021844.1\|WP_000017103.1\|898675_899092_-\|Holliday-junction-resolvase-RuvX	gnl\|CDD\|234639	PRK00109, PRK00109, Holliday junction resolvase RuvX.	1.59906e-77
NZ_CP021844.1\|WP_001222509.1\|900726_901458_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|272873	TIGR00046, Ribosomal_RNA_small_subunit_methyltransferase_E, RNA methyltransferase, RsmE family. Members of this protein family, previously called conserved hypothetical protein TIGR00046, include the YggJ protein of E. coli, which has now been shown to methylate U1498 in 16S rRNA. [Protein synthesis, tRNA and rRNA base modification].	1.38944e-113
NZ_CP021844.1\|WP_001277222.1\|895918_896209_-\|YggU-family-protein	gnl\|CDD\|179931	PRK05090, PRK05090, hypothetical protein; Validated.	2.89123e-62
NZ_CP021844.1\|WP_021577908.1\|883348_885484_+\|ornithine-decarboxylase	gnl\|CDD\|237434	PRK13578, PRK13578, ornithine decarboxylase; Provisional.	0
NZ_CP021844.1\|WP_000593273.1\|899763_900714_-\|glutathione-synthase	gnl\|CDD\|235371	PRK05246, PRK05246, glutathione synthetase; Provisional.	0
NZ_CP021844.1\|WP_021577907.1\|888438_889491_-\|A/G-specific-adenine-glycosylase	gnl\|CDD\|182805	PRK10880, PRK10880, adenine DNA glycosylase.	0
NZ_CP021844.1\|WP_000760323.1\|886991_888071_-\|membrane-bound-lytic-murein-transglycosylase-MltC	gnl\|CDD\|183271	PRK11671, mltC, membrane-bound lytic murein transglycosylase MltC.	0
NZ_CP021844.1\|WP_000394107.1\|891775_892822_+\|L-asparaginase-2	gnl\|CDD\|182958	PRK11096, ansB, L-asparaginase II; Provisional.	0
NZ_CP021844.1\|WP_000997795.1\|896789_897494_-\|pyridoxal-phosphate-homeostasis-protein	gnl\|CDD\|143497	cd06824, PLPDE_III_Yggs_like, Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins. This subfamily contains mainly uncharacterized proteobacterial proteins with similarity to the hypothetical Escherichia coli protein YggS, a homolog of yeast YBL036c, which is homologous to a Pseudomonas aeruginosa gene that is co-transcribed with a known proline biosynthetic gene. Like yeast YBL036c, Yggs is a single domain monomeric protein with a typical TIM-barrel fold. Its structure, which shows a covalently-bound PLP cofactor, is similar to the N-terminal domain of the fold type III PLP-dependent enzymes, bacterial alanine racemase and eukaryotic ornithine decarboxylase, which are two-domain dimeric proteins. YggS has not been characterized extensively and its biological function is still unkonwn.	7.52959e-146
NZ_CP021844.1\|WP_000745237.1\|892938_893946_+\|DUF1202-family-protein	gnl\|CDD\|284194	pfam06717, DUF1202, Protein of unknown function (DUF1202). This family consists of several hypothetical bacterial proteins of around 335 residues in length. Members of this family are found exclusively in Escherichia coli and Salmonella species and are often referred to as YggM proteins. The function of this family is unknown.	0
NZ_CP021844.1\|WP_000786911.1\|889651_890371_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	4.68332e-106
NZ_CP021844.1\|WP_001053178.1\|899091_899655_-\|YqgE/AlgH-family-protein	gnl\|CDD\|234694	PRK00228, PRK00228, YqgE/AlgH family protein.	1.27728e-101
NZ_CP021844.1\|WP_000984796.1\|890880_891600_+\|DUF2884-domain-containing-protein	gnl\|CDD\|182597	PRK10626, PRK10626, hypothetical protein; Provisional.	1.42493e-154
NZ_CP021844.1\|WP_021577906.1\|897511_898492_+\|type-IV-pilus-twitching-motility-protein-PilT	gnl\|CDD\|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP021844.1\|WP_001107564.1\|890370_890697_+\|YggL-family-protein	gnl\|CDD\|183281	PRK11702, PRK11702, hypothetical protein; Provisional.	8.94191e-74
NZ_CP021844.1\|WP_001174750.1\|895317_895911_-\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	4.99769e-127
NZ_CP021844.1\|WP_001049791.1\|885533_886790_-\|nucleoside-permease	gnl\|CDD\|129967	TIGR00889, Putative_nucleoside_transporter_YegT, nucleoside transporter. This family of proteins transports nucleosides at a high affinity. The transport mechanism is driven by proton motive force. This family includes nucleoside permease NupG and xanthosine permease from E.Coli. [Transport and binding proteins, Nucleosides, purines and pyrimidines].	0
NZ_CP021844.1\|WP_001094831.1\|896205_896772_-\|osmotic-shock-tolerance-protein-YggT	gnl\|CDD\|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	1.9713e-11

>NZ_CP021844.1|WP_000745237.1|892938_893946_+|DUF1202-family-protein
MKKQWIVGTALLMLMTGNVWADGEPPTENILKDQFKKQYHGILKLDAITLKNLDAKGNQATWSAEGDVSSNDDLYTWVGQLADYELLEQTWTKDKAVKFSAMLTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALNTQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDEFNKQNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLSRKLQDDWITLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVIK
>NZ_CP021844.1|WP_000394107.1|891775_892822_+|L-asparaginase-2
MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATKSNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDDVWLTLAKKINTDCDKTDGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAADKASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARKHTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKTVFDTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQTKDPQQIQQIFNQY
>NZ_CP021844.1|WP_000984796.1|890880_891600_+|DUF2884-domain-containing-protein
MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGENGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIALDKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLVNQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGKDVCSRVVTLEDSRKALVGNLK
>NZ_CP021844.1|WP_001107564.1|890370_890697_+|YggL-family-protein
MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDDFINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLDEVRTSELFDVWWD
>NZ_CP021844.1|WP_000786911.1|889651_890371_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
>NZ_CP021844.1|WP_021577907.1|888438_889491_-|A/G-specific-adenine-glycosylase
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLCKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAATNNSWSLYPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQRQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFAGCMDEGNALWYNLAQPPSVGLAAPVERLLQQLRTGAPV
>NZ_CP021844.1|WP_000091700.1|888135_888411_-|oxidative-damage-protection-protein
MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK
>NZ_CP021844.1|WP_000760323.1|886991_888071_-|membrane-bound-lytic-murein-transglycosylase-MltC
MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
>NZ_CP021844.1|WP_001049791.1|885533_886790_-|nucleoside-permease
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAQVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHMQLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMAMFKYKHVRVPTGTQTVSH
>NZ_CP021844.1|WP_021577908.1|883348_885484_+|ornithine-decarboxylase
MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSRSGILTLLKRTGFHLPVFLYSEHAVELPAGVTAVINGNEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGDLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKAELPRPFRLAIIQLGTYDGTVYNARQVIDTIGHLCDYILFDSAWVGYELFIPMMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESGRRLWAECVELGIESRKAILARCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGDVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGMKRLYGYVLK
>NZ_CP021844.1|WP_000239959.1|894188_895325_-|radical-SAM-family-heme-chaperone-HemW
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVKTIFIGGGTPSLLSGSAMQTLLDGVRARLPLAADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSFNLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEPAPRVEFSAYTGLCEDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE
>NZ_CP021844.1|WP_001174750.1|895317_895911_-|XTP/dITP-diphosphatase
MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGLTFIENAILKARHAAKVTGLPAIADDSGLAVDVLGGAPGIYSARYSGEDATDQKNLQKLLETLKDVPDEQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIFFVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG
>NZ_CP021844.1|WP_001277222.1|895918_896209_-|YggU-family-protein
MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN
>NZ_CP021844.1|WP_001094831.1|896205_896772_-|osmotic-shock-tolerance-protein-YggT
MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVTQPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTIGLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVLLLYVINMGVAEVLQATGNMLLPGLWMAL
>NZ_CP021844.1|WP_000997795.1|896789_897494_-|pyridoxal-phosphate-homeostasis-protein
MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIAEAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHTIDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRLRGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTMVRIGTAIFGARDYSKK
>NZ_CP021844.1|WP_021577906.1|897511_898492_+|type-IV-pilus-twitching-motility-protein-PilT
MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGLMEAAPFDAPDVEELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRQGISMALRLLPSHCPQLEQLGAPTVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVEYLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETGHLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVALFELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQQRVGEGRL
>NZ_CP021844.1|WP_000017103.1|898675_899092_-|Holliday-junction-resolvase-RuvX
MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNIIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVDVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY
>NZ_CP021844.1|WP_001053178.1|899091_899655_-|YqgE/AlgH-family-protein
MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
>NZ_CP021844.1|WP_000593273.1|899763_900714_-|glutathione-synthase
MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLYLINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILKPLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ
>NZ_CP021844.1|WP_001222509.1|900726_901458_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLG

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Crispr_ID: NZ_CP021844_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_2

1111393-1111665

Unclear

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

4 spacers

The CRISPR arrays of NZ_CP021844_2

>merge|NZ_CP021844|2|1111393-1111665|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCGGCCCTATAATGAGAAATAAACTAATTCCTATTGAGTTCCCCGCGCCAGCGGGGATAAACCGCAAAAACAATCAGGAGAGGCGCTGGCACACCAGAGTTCCCCGCGCCAGCGGGGATAAACCGATTAGCCGCTTCACTAAACCGCGCGCCAGTGCGAGTTCCCCGCGCCAGCGGGGATAAACCGGGTACAAAAGAGGCCCCATTCTGGCAGGGCTCGAGTTCCCCGCGCCAGTGGGGATAAACCA

>NZ_CP021844|2|1|1111393-1111665|PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCCCTATAATGAGAAATAAACTAATTCCTATT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CAAAAACAATCAGGAGAGGCGCTGGCACACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTAGCCGCTTCACTAAACCGCGCGCCAGTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGTACAAAAGAGGCCCCATTCTGGCAGGGCTC
GAGTTCCCCGCGCCAGTGGGGATAAACCA

>NZ_CP021844|2|2|1111393-1111665|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCCCTATAATGAGAAATAAACTAATTCCTATT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CAAAAACAATCAGGAGAGGCGCTGGCACACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTAGCCGCTTCACTAAACCGCGCGCCAGTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGTACAAAAGAGGCCCCATTCTGGCAGGGCTC
GAGTTCCCCGCGCCAGTGGGGATAAACCA

>NZ_CP021844|2|1|1111393-1111665|CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCCCTATAATGAGAAATAAACTAATTCCTATT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CAAAAACAATCAGGAGAGGCGCTGGCACACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTAGCCGCTTCACTAAACCGCGCGCCAGTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGTACAAAAGAGGCCCCATTCTGGCAGGGCTC
GAGTTCCCCGCGCCAGTGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_021577860.1\|1115403_1116189_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP021844.1\|WP_088172186.1\|1113808_1115086_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP021844.1\|WP_000254735.1\|1102132_1102468_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP021844.1\|WP_021574746.1\|1119897_1120758_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP021844.1\|WP_001243482.1\|1108715_1109594_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP021844.1\|WP_000059300.1\|1116258_1117713_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP021844.1\|WP_000210878.1\|1103558_1105196_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP021844.1\|WP_021577863.1\|1102539_1103331_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP021844.1\|WP_001199973.1\|1110382_1111054_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP021844.1\|WP_001625784.1\|1119121_1119901_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP021844.1\|WP_021577858.1\|1121747_1123019_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP021844.1\|WP_088172187.1\|1107552_1108701_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP021844.1\|WP_021577862.1\|1112303_1113782_-\|kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP021844.1\|WP_021577864.1\|1101884_1102133_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP021844.1\|WP_001313221.1\|1106641_1107556_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP021844.1\|WP_001625782.1\|1121496_1121757_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP021844.1\|WP_001625785.1\|1117806_1119144_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP021844.1\|WP_000944226.1\|1109607_1110210_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP021844.1\|WP_000036723.1\|1105283_1106582_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP021844.1\|WP_001130271.1\|1120904_1121480_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_021577860.1\|1115403_1116189_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.00269e-138
NZ_CP021844.1\|WP_088172186.1\|1113808_1115086_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.09872e-29
NZ_CP021844.1\|WP_000254735.1\|1102132_1102468_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	6.85168e-74
NZ_CP021844.1\|WP_021574746.1\|1119897_1120758_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	1.96726e-89
NZ_CP021844.1\|WP_001243482.1\|1108715_1109594_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	7.71052e-89
NZ_CP021844.1\|WP_000059300.1\|1116258_1117713_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	6.77396e-83
NZ_CP021844.1\|WP_000210878.1\|1103558_1105196_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP021844.1\|WP_021577863.1\|1102539_1103331_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	1.41027e-156
NZ_CP021844.1\|WP_001199973.1\|1110382_1111054_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP021844.1\|WP_001625784.1\|1119121_1119901_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	4.134e-63
NZ_CP021844.1\|WP_021577858.1\|1121747_1123019_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	7.83257e-125
NZ_CP021844.1\|WP_088172187.1\|1107552_1108701_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.0727e-61
NZ_CP021844.1\|WP_021577862.1\|1112303_1113782_-\|kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	5.91434e-109
NZ_CP021844.1\|WP_021577864.1\|1101884_1102133_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	9.15005e-48
NZ_CP021844.1\|WP_001313221.1\|1106641_1107556_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.18265e-104
NZ_CP021844.1\|WP_001625782.1\|1121496_1121757_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	5.43953e-42
NZ_CP021844.1\|WP_001625785.1\|1117806_1119144_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.41799e-50
NZ_CP021844.1\|WP_000944226.1\|1109607_1110210_-\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	1.21919e-77
NZ_CP021844.1\|WP_000036723.1\|1105283_1106582_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP021844.1\|WP_001130271.1\|1120904_1121480_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.57069e-87

>NZ_CP021844.1|WP_001199973.1|1110382_1111054_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP021844.1|WP_000944226.1|1109607_1110210_-|LemA-family-protein
MLRIFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSSHERDVLEAVTLARSQANRASSDLQQTPGDEQKLQAWQQAQAQVTRTLGQLTIISERYPELKSQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNANAH
>NZ_CP021844.1|WP_001243482.1|1108715_1109594_-|YgcG-family-protein
MRNFIFLMAFFCSSVFATQIPVPESPKYVNDLTGTLTNSEVNTLTKQIKALTQKSHAQLVVLVVETTGDETIEQYATRVFDSWKPGDKDRDDGVLLLVAWQDHTVRIEIGYGLEGIITDAQSGQIIRNSIIPAFKNGDLAGGLQKGLSDIENRLAGNNLATIAPADHPLPFSGWWALLAWAIVLTFISARGYIKTLGVICFAAIVLAFVLPIAGFSGSWGVLTTLLCFATPFLAVAIAFTPFGKKVRDLMRDANQPSRHTRSNSFSHYSSSSSSSFDNDNFSGGGGGASGRW
>NZ_CP021844.1|WP_088172187.1|1107552_1108701_-|YgcG-family-protein
MRIFLLLLMLCGFQVFAERLPSVNDLTGTLTTEEQSVLNQQLKTLEQKNHFQVAVLVTPTTGGKNIKLAASQRYGVYHWKPVGEKRYGEGILILVVWPEGLASMKIGHGLEQMLPPEQAAQIVRYHMQPEFEKNNLFAGLTGGIESIAQFTHIKANISPLDALANHLFANPQRSLPCLAWTLLMIVAIVVLWRFASRPRRGIWMISMITPMVWFFSFQDDVIIRRVSVVCFSLLLATTCKQRLAVVFNLCRVFPMMLAPKNKNAKVKKQKKTPQVRKSGRNSLFVVMLIIIVGWCLVFASNKDIAFISTIIGLIDHFIGPITIAGIVLLIIVAKFTGNLKLGSGEKSNRKTGNRNAHSRSSSRNSFRGGGGSSGGGGSSGRW
>NZ_CP021844.1|WP_001313221.1|1106641_1107556_-|YgcG-family-protein
MIVMRLIFILFTLWCLPGLAQQIAVPELRQQVTDITGTLSTSEQQSLTQQLQDITHKTRAQVAVLVVPSTGDDSIEQYATRVFDSWKLGDKQRNDGILLLVAWEDHAVRIEVGYGLEGVVTDLQAAKIIRDILIPAFKSDDLMGGLTLASENIGALLLNGELPEDRGDYYSINPPIPLSLAVIILLAVLSYFIVFTDPSNLPWITLTGAIYGMVFLYVAEPGPWTNLIVACGMLTPFAIVPLVIFWLIVNKKLRAKYKKLSKERASRKGSSSSSSGGGSSGGGSGGGFSGGGGSSGGGGASGRW
>NZ_CP021844.1|WP_000036723.1|1105283_1106582_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP021844.1|WP_000210878.1|1103558_1105196_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP021844.1|WP_021577863.1|1102539_1103331_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFSSIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADGSAGNSREVLARWEEIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFELRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP021844.1|WP_000254735.1|1102132_1102468_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRAKGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP021844.1|WP_021577864.1|1101884_1102133_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSIKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP021844.1|WP_021577862.1|1112303_1113782_-|kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKTWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPETLLYEGYGIRKGMWTVSWLRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDTMNKGIFKDLTKHTDVILKKSYEVMHGELGNADSIQSWSNA
>NZ_CP021844.1|WP_088172186.1|1113808_1115086_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKPPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALGMVIVFTFLLFQKIRTADIAPTTANSK
>NZ_CP021844.1|WP_021577860.1|1115403_1116189_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKKMIENQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASQASNYVNGHLLVVDGGYLVR
>NZ_CP021844.1|WP_000059300.1|1116258_1117713_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP021844.1|WP_001625785.1|1117806_1119144_+|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGVLLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLASAAMPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLILAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP021844.1|WP_001625784.1|1119121_1119901_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGNSGPDVSLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAAELRFAPEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCRQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP021844.1|WP_021574746.1|1119897_1120758_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTISVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP021844.1|WP_001130271.1|1120904_1121480_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRQFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP021844.1|WP_001625782.1|1121496_1121757_-|ferredoxin-family-protein
MSVARNLWRAADAPHIVPADSVERQTAERLINACPAGLFALTPEGDLRVDYRGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP021844.1|WP_021577858.1|1121747_1123019_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVVEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTYPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLLWRHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: NZ_CP021844_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_3

1137357-1137812

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

7 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP021844_3

>merge|NZ_CP021844|3|1137357-1137812|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGTCAAATCGGTTACCTTAACCTGTTGAATGTGGTGTTCCCCGCGCCAGCGGGGATAAACCGAACGGCTACGGCACCGAGGTGACAAACCAGATGTGTTCCCCGCGCCAGCGGGGATAAACCGATTACGACTTCCGCACGCACCCACCGTTTGTAGTGTTCCCCGCGCCAGCGGGGATAAACCGTTGGGCTAGGAGGAAGAGCATCATTAACATGGGTGTTCCCCGCGCCAGCGGGGATAAACCGTAAACCCCTCGCGCATCGAGTCAAATGTCGGAGTGTTCCCCGCGCCAGCGGGGATAAACCGTACGTGTCGCCGTTACAGATTTCAGTCTGTTAGTGTTCCCCGCGCCAGCGGGGATAAACCGCACGATTTTATGTGCCGCGTTGAGGCGTGGGCGTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP021844|3|2|1137357-1137812|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCAAATCGGTTACCTTAACCTGTTGAATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AACGGCTACGGCACCGAGGTGACAAACCAGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTACGACTTCCGCACGCACCCACCGTTTGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGGGCTAGGAGGAAGAGCATCATTAACATGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAACCCCTCGCGCATCGAGTCAAATGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGTGTCGCCGTTACAGATTTCAGTCTGTTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACGATTTTATGTGCCGCGTTGAGGCGTGGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP021844|3|3|1137357-1137812|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCAAATCGGTTACCTTAACCTGTTGAATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AACGGCTACGGCACCGAGGTGACAAACCAGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTACGACTTCCGCACGCACCCACCGTTTGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGGGCTAGGAGGAAGAGCATCATTAACATGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAACCCCTCGCGCATCGAGTCAAATGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGTGTCGCCGTTACAGATTTCAGTCTGTTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACGATTTTATGTGCCGCGTTGAGGCGTGGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP021844|3|2|1137357-1137812|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCAAATCGGTTACCTTAACCTGTTGAATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AACGGCTACGGCACCGAGGTGACAAACCAGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTACGACTTCCGCACGCACCCACCGTTTGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGGGCTAGGAGGAAGAGCATCATTAACATGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAACCCCTCGCGCATCGAGTCAAATGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGTGTCGCCGTTACAGATTTCAGTCTGTTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACGATTTTATGTGCCGCGTTGAGGCGTGGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_000039866.1\|1127362_1128097_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP021844.1\|WP_000029319.1\|1133054_1133591_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP021844.1\|WP_000246138.1\|1143021_1143732_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP021844.1\|WP_001295182.1\|1145237_1145999_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP021844.1\|WP_001246104.1\|1142174_1142498_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP021844.1\|WP_000956458.1\|1128362_1128515_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP021844.1\|WP_021577852.1\|1136046_1136970_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP021844.1\|WP_001219242.1\|1143731_1144211_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP021844.1\|WP_021577853.1\|1135399_1136050_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP021844.1\|WP_000517476.1\|1142691_1143003_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP021844.1\|WP_000063176.1\|1136966_1137260_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP021844.1\|WP_000206438.1\|1133605_1134661_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP021844.1\|WP_000372392.1\|1139182_1140091_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP021844.1\|WP_021577851.1\|1137893_1138931_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP021844.1\|WP_001090361.1\|1140092_1141520_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP021844.1\|WP_021577856.1\|1128706_1131406_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP021844.1\|WP_021577854.1\|1134671_1135418_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP021844.1\|WP_001173673.1\|1141519_1142125_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP021844.1\|WP_021577855.1\|1131495_1133058_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP021844.1\|WP_000568924.1\|1144207_1145257_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_000039866.1\|1127362_1128097_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.29883e-136
NZ_CP021844.1\|WP_000029319.1\|1133054_1133591_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	8.02591e-28
NZ_CP021844.1\|WP_000246138.1\|1143021_1143732_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP021844.1\|WP_001295182.1\|1145237_1145999_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP021844.1\|WP_001246104.1\|1142174_1142498_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP021844.1\|WP_000956458.1\|1128362_1128515_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP021844.1\|WP_021577852.1\|1136046_1136970_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	7.72092e-153
NZ_CP021844.1\|WP_001219242.1\|1143731_1144211_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP021844.1\|WP_021577853.1\|1135399_1136050_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	8.48661e-92
NZ_CP021844.1\|WP_000517476.1\|1142691_1143003_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP021844.1\|WP_000063176.1\|1136966_1137260_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP021844.1\|WP_000206438.1\|1133605_1134661_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.77838e-155
NZ_CP021844.1\|WP_000372392.1\|1139182_1140091_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP021844.1\|WP_021577851.1\|1137893_1138931_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP021844.1\|WP_001090361.1\|1140092_1141520_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP021844.1\|WP_021577856.1\|1128706_1131406_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP021844.1\|WP_021577854.1\|1134671_1135418_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.79617e-48
NZ_CP021844.1\|WP_001173673.1\|1141519_1142125_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP021844.1\|WP_021577855.1\|1131495_1133058_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	4.17204e-173
NZ_CP021844.1\|WP_000568924.1\|1144207_1145257_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0

>NZ_CP021844.1|WP_000063176.1|1136966_1137260_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP021844.1|WP_021577852.1|1136046_1136970_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTRIRTHIPVGSVAYIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQLAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP021844.1|WP_021577853.1|1135399_1136050_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRSFVPELRTGQQLCFNLRANPTICKAGKRHDLLMEAKRQMRGQAEGSDVWLHQQQAALDWLAVQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP021844.1|WP_021577854.1|1134671_1135418_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTIQMPKEVRKARYFSRREELSDPDLLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQGGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYHQYQEHFHDLKIALPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP021844.1|WP_000206438.1|1133605_1134661_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRIAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP021844.1|WP_000029319.1|1133054_1133591_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSEGRFTRLSAVKTPDDLLRQLRRAVKLLNGSVNLISLAEDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>NZ_CP021844.1|WP_021577855.1|1131495_1133058_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALLLLEHAFQFGPDSPSFMQDFEELRVKVSSIASLLPDTPGKQTKERNKDHFIKRGTIQHICLHCVPLALFSIQLNAPKGGRGYYPGLRGGGPLTTLIELLEYQGNPQPPLWRKLWLNVMPQDEADLPLPKTFDDLVFPWLAPTRTCELDGAVITDEQVNKLQAYWGMPRRIRIDFKTTSIGNCDICDSQSGALLSLMALKNNGVQYVMWRHPLTPYRMPLKEGGEFYSVKPQPGGLIWRDWLGLIEEGKSKNNTELPAQVVKLFNASNLKQTKIGLWGFGYDFEDMKVRCWYEHHFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDPDELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQNAKAAREKKQEAAE
>NZ_CP021844.1|WP_021577856.1|1128706_1131406_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRDEKEGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLHPQLKVPEGARKNYEKISHSTLGYWLWHHYLSECEELLPASSLSTRKLKRVIAMWMPMTTGHHGRPPDRIDELDNFLPEDKVAARDFLLEIKALCPLIEIPTFWDNDEGVELLKQLSWYISATVVLADWTGSSTRFFPRVAHPMDIKDYWQKTLVQAQNALTVFPPKAETAPFTGVNTLFPFIEHPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLMAARKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLTHSARTLMDRFNESLWSGDLVGSEEPDEQAFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKNCNLKRSSQVIVCTQVIEQSVDIDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFMLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYASGAHAWEMSVARVRRSWWKKHRDEFSLLEGEAFRQWCVEQRQDPEMANVILVTDDESCGYSAREGLIGKVD
>NZ_CP021844.1|WP_000956458.1|1128362_1128515_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP021844.1|WP_000039866.1|1127362_1128097_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALRDLNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP021844.1|WP_021577851.1|1137893_1138931_-|aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGIDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP021844.1|WP_000372392.1|1139182_1140091_+|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP021844.1|WP_001090361.1|1140092_1141520_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP021844.1|WP_001173673.1|1141519_1142125_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP021844.1|WP_001246104.1|1142174_1142498_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP021844.1|WP_000517476.1|1142691_1143003_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP021844.1|WP_000246138.1|1143021_1143732_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP021844.1|WP_001219242.1|1143731_1144211_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP021844.1|WP_000568924.1|1144207_1145257_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP021844.1|WP_001295182.1|1145237_1145999_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP021844_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_4

1741075-1741192

Orphan

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_4

>merge|NZ_CP021844|4|1741075-1741192|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGAGGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>NZ_CP021844|4|4|1741075-1741192|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGAGGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_001613489.1\|1735451_1736531_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
NZ_CP021844.1\|WP_000857257.1\|1732187_1733816_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847
NZ_CP021844.1\|WP_000332037.1\|1739847_1740978_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	unknown	unknown	gnl\|CDD\|181647
NZ_CP021844.1\|WP_000135040.1\|1739593_1739848_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	unknown	unknown	gnl\|CDD\|182668
NZ_CP021844.1\|WP_000580275.1\|1762296_1763619_-\|TIGR00366-family-protein	unknown	unknown	gnl\|CDD\|280776
NZ_CP021844.1\|WP_000990765.1\|1748085_1748808_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	unknown	unknown	gnl\|CDD\|235350
NZ_CP021844.1\|WP_000660231.1\|1737618_1738809_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP021844.1\|WP_001209887.1\|1730938_1732198_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	unknown	unknown	gnl\|CDD\|225617
NZ_CP021844.1\|WP_000948724.1\|1734088_1735447_+\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
NZ_CP021844.1\|WP_000176730.1\|1736575_1737454_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP021844.1\|WP_001281220.1\|1748954_1751582_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	unknown	unknown	gnl\|CDD\|235502
NZ_CP021844.1\|WP_001075172.1\|1741211_1743497_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181649
NZ_CP021844.1\|WP_000301028.1\|1738889_1739540_+\|lipopolysaccharide-kinase-InaA	unknown	unknown	gnl\|CDD\|182136
NZ_CP021844.1\|WP_021577729.1\|1753415_1754039_+\|DUF1175-domain-containing-protein	unknown	unknown	gnl\|CDD\|225774
NZ_CP021844.1\|WP_021577727.1\|1758577_1760227_+\|DUF2300-domain-containing-protein	unknown	unknown	gnl\|CDD\|227732
NZ_CP021844.1\|WP_001225837.1\|1760231_1761008_+\|YfaP-family-protein	unknown	unknown	gnl\|CDD\|227021
NZ_CP021844.1\|WP_021577726.1\|1761081_1762266_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
NZ_CP021844.1\|WP_001000379.1\|1729751_1730942_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
NZ_CP021844.1\|WP_021577728.1\|1754182_1758577_+\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP021844.1\|WP_021577730.1\|1751730_1753419_+\|DUF2138-domain-containing-protein	unknown	unknown	gnl\|CDD\|227030

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_001613489.1\|1735451_1736531_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
NZ_CP021844.1\|WP_000857257.1\|1732187_1733816_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
NZ_CP021844.1\|WP_000332037.1\|1739847_1740978_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
NZ_CP021844.1\|WP_000135040.1\|1739593_1739848_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
NZ_CP021844.1\|WP_000580275.1\|1762296_1763619_-\|TIGR00366-family-protein	gnl\|CDD\|280776	pfam02667, SCFA_trans, Short chain fatty acid transporter. This family consists of two sequences annotated as short chain fatty acid transporters, however, there are no references giving details of experimental characterization of this function.	0
NZ_CP021844.1\|WP_000990765.1\|1748085_1748808_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	1.65303e-171
NZ_CP021844.1\|WP_000660231.1\|1737618_1738809_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.20553e-100
NZ_CP021844.1\|WP_001209887.1\|1730938_1732198_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP021844.1\|WP_000948724.1\|1734088_1735447_+\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
NZ_CP021844.1\|WP_000176730.1\|1736575_1737454_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.04797e-45
NZ_CP021844.1\|WP_001281220.1\|1748954_1751582_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NZ_CP021844.1\|WP_001075172.1\|1741211_1743497_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
NZ_CP021844.1\|WP_000301028.1\|1738889_1739540_+\|lipopolysaccharide-kinase-InaA	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	4.41923e-159
NZ_CP021844.1\|WP_021577729.1\|1753415_1754039_+\|DUF1175-domain-containing-protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	6.91917e-139
NZ_CP021844.1\|WP_021577727.1\|1758577_1760227_+\|DUF2300-domain-containing-protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	9.28246e-127
NZ_CP021844.1\|WP_001225837.1\|1760231_1761008_+\|YfaP-family-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	1.68073e-151
NZ_CP021844.1\|WP_021577726.1\|1761081_1762266_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP021844.1\|WP_001000379.1\|1729751_1730942_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
NZ_CP021844.1\|WP_021577728.1\|1754182_1758577_+\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP021844.1\|WP_021577730.1\|1751730_1753419_+\|DUF2138-domain-containing-protein	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0

>NZ_CP021844.1|WP_000332037.1|1739847_1740978_-|ribonucleoside-diphosphate-reductase-1-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>NZ_CP021844.1|WP_000135040.1|1739593_1739848_-|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>NZ_CP021844.1|WP_000301028.1|1738889_1739540_+|lipopolysaccharide-kinase-InaA
MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVTPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIYVKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>NZ_CP021844.1|WP_000660231.1|1737618_1738809_+|MFS-transporter
MKEKLWTKDFWAITIISFIIFFVFYVLLTLLPIYISDRLHASPDKAGLLVTLFLIAAIVIRPFAGQWVGKYSNKTILVLSSLAFLVVTALYPFCHSIESLLFIRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWEAFNMAFWLCTGVAAVGIILSLIMTVPPVISHADGSKPKMGFAAMFDRAALPFAMVTFFMTFSYAGVSAFLALYARELNLMSAASNFLLCYAIFLMICRTFTGNVCDKKGPKYVVYPCLLFFTVGLVVLGYTQGSVMMVVSGALIGIGYGSVTPVFQTQIISSVEPHKIGVANSLFFNAMDAGLALGACVMGMMVAHTGYRMIYLLGALLVVVAGGVYALQMKGKSGVALVVAKEIH
>NZ_CP021844.1|WP_000176730.1|1736575_1737454_-|LysR-family-transcriptional-regulator
MTLTQIHTLLAVLDYGGFTEASKRLFMTQSAVSQAIATLEQELGVEILIRERRKALQLTDAGSRIASHLRAITREVNAVKEIAEQEKHNPTRTLRIGCFPSACACILPGIIRYFETYHPQIKIIPYEENSSEIIDSVQNETIDAGFVHFPVTGMYSVPVYQDKFTVVLPDAHPLAKNNAISVEELVGEPLIISKGRYELSIMALFKEKNITPVIKYEFNHPDTAISFIRQGLGIALLPELTLKAVAGELCSVPLEPTFYRQISLLVKEAPVEGSPLFLLQMCMETLVVKGIL
>NZ_CP021844.1|WP_001613489.1|1735451_1736531_+|glycerophosphodiester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLHKDN
>NZ_CP021844.1|WP_000948724.1|1734088_1735447_+|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHQELLQKRNGG
>NZ_CP021844.1|WP_000857257.1|1732187_1733816_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>NZ_CP021844.1|WP_001209887.1|1730938_1732198_-|glycerol-3-phosphate-dehydrogenase-subunit-GlpB
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQAVTDIHSGLESLRQQAPAHPYSLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDQTLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>NZ_CP021844.1|WP_001000379.1|1729751_1730942_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>NZ_CP021844.1|WP_001075172.1|1741211_1743497_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>NZ_CP021844.1|WP_000990765.1|1748085_1748808_-|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>NZ_CP021844.1|WP_001281220.1|1748954_1751582_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVEGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>NZ_CP021844.1|WP_021577730.1|1751730_1753419_+|DUF2138-domain-containing-protein
MSGEKKAKGWRFYGLVGFSAIALLSAGFWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLNKTEISSIKINSETIPVYQLRYNGNNVLMFATYQDKMLVFSSTDMLFKDDQQDTEATAIASDLLSGKKRWQASFGLEERTAEKTPVRQRIVVSARLLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>NZ_CP021844.1|WP_021577729.1|1753415_1754039_+|DUF1175-domain-containing-protein
MRHVLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANEALKVHDSKWLKNNGFSNQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>NZ_CP021844.1|WP_021577728.1|1754182_1758577_+|alpha-2-macroglobulin-family-protein
MRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELHLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQAKPVEPQQGVKLDGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSNTVALSKVSGKELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLMQTVDVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGDLPSGGKSFTVNFDKPGNYNLTLRDKDGLILAGLSHAVSGKGSMSHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSGKNLYMKWSMPTVYRVGDKPSAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLAQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDPRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>NZ_CP021844.1|WP_021577727.1|1758577_1760227_+|DUF2300-domain-containing-protein
MNWRRIVWLLALVTLPTLAEETPLQLALRGAQHDQLYQLSSSGVTKASTLPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTSVKPGVLNGRYRVTFANGNHITFVSHGETTLLTEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMTAWTQDLIYAGDPVHYHGSRATEGTLSWRQAMAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKKMPQWRRILQGETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>NZ_CP021844.1|WP_001225837.1|1760231_1761008_+|YfaP-family-protein
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASFSQSINYPASSVNMADDQNISAQIHGKIKNYAAAGKVQQGRLVVNGASMPQRVESDGSFARPYIFTEGSNSVQVISPDGRSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>NZ_CP021844.1|WP_021577726.1|1761081_1762266_-|acetyl-CoA-C-acetyltransferase
MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSLHIDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKADSTTEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKSLGFDSEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVMERLN
>NZ_CP021844.1|WP_000580275.1|1762296_1763619_-|TIGR00366-family-protein
MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPLLAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF

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Crispr_ID: NZ_CP021844_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_5

1972830-1972964

Orphan

Consensus_repeat	Method
TGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_5

>merge|NZ_CP021844|5|1972830-1972964|CRISPRCasFinder
TGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCACTGAATGCCGGATGCGGCGTAAAACGCCTTATCCGGCCTACGGTTCTGTGCTCGGGTCTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA

>NZ_CP021844|5|5|1972830-1972964|CRISPRCasFinder
TGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA	CTGAATGCCGGATGCGGCGTAAAACGCCTTATCCGGCCTACGGTTCTGTGCTCGGGTCT
TGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_000183133.1\|1969873_1971268_+\|undecaprenyl-phosphate-glucose-phosphotransferase	unknown	unknown	gnl\|CDD\|182254
NZ_CP021844.1\|WP_001116129.1\|1975532_1976927_+\|colanic-acid-biosynthesis-protein-WcaM	unknown	unknown	gnl\|CDD\|182253
NZ_CP021844.1\|WP_053882441.1\|1977084_1978080_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187549
NZ_CP021844.1\|WP_000699721.1\|1965505_1966729_+\|colanic-acid-biosynthesis-fucosyltransferase-WcaI	unknown	unknown	gnl\|CDD\|188522
NZ_CP021844.1\|WP_000862654.1\|1974301_1975522_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaL	unknown	unknown	gnl\|CDD\|188520
NZ_CP021844.1\|WP_001298845.1\|1965029_1965509_+\|GDP-mannose-mannosyl-hydrolase	unknown	unknown	gnl\|CDD\|237966
NZ_CP021844.1\|WP_060684448.1\|1983128_1984688_+\|O51-family-O-antigen-flippase	unknown	unknown	gnl\|CDD\|240533
NZ_CP021844.1\|WP_000183060.1\|1978322_1979216_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalF	unknown	unknown	gnl\|CDD\|182252
NZ_CP021844.1\|WP_033870517.1\|1979587_1980673_+\|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|236649
NZ_CP021844.1\|WP_000048190.1\|1962937_1964059_+\|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224014
NZ_CP021844.1\|WP_000043590.1\|1964061_1965027_+\|GDP-L-fucose-synthase	unknown	unknown	gnl\|CDD\|187550
NZ_CP021844.1\|WP_044863830.1\|1980672_1981572_+\|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl\|CDD\|182184
NZ_CP021844.1\|WP_000770774.1\|1973024_1974305_+\|colanic-acid-biosynthesis-pyruvyl-transferase-WcaK	unknown	unknown	gnl\|CDD\|188521
NZ_CP021844.1\|WP_001153551.1\|1962362_1962911_+\|colanic-acid-biosynthesis-acetyltransferase-WcaF	unknown	unknown	gnl\|CDD\|188523
NZ_CP021844.1\|WP_033870520.1\|1982512_1983055_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl\|CDD\|376414
NZ_CP021844.1\|WP_000927041.1\|1961600_1962347_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaE	unknown	unknown	gnl\|CDD\|182218
NZ_CP021844.1\|WP_033870519.1\|1981629_1982508_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|185377
NZ_CP021844.1\|WP_001355594.1\|1968448_1969819_+\|phosphomannomutase-CpsG	unknown	unknown	gnl\|CDD\|185312
NZ_CP021844.1\|WP_000079280.1\|1966731_1968168_+\|mannose-1-phosphate-guanyltransferase	unknown	unknown	gnl\|CDD\|185357
NZ_CP021844.1\|WP_000058435.1\|1971269_1972748_+\|M-antigen-undecaprenyl-disphosphate-flippase	unknown	unknown	gnl\|CDD\|236697

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_000183133.1\|1969873_1971268_+\|undecaprenyl-phosphate-glucose-phosphotransferase	gnl\|CDD\|182254	PRK10124, PRK10124, putative UDP-glucose lipid carrier transferase; Provisional.	0
NZ_CP021844.1\|WP_001116129.1\|1975532_1976927_+\|colanic-acid-biosynthesis-protein-WcaM	gnl\|CDD\|182253	PRK10123, wcaM, putative colanic acid biosynthesis protein; Provisional.	0
NZ_CP021844.1\|WP_053882441.1\|1977084_1978080_+\|SDR-family-oxidoreductase	gnl\|CDD\|187549	cd05238, Gne_like_SDR_e, Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs. Nucleoside-diphosphate-sugar 4-epimerase has the characteristic active site tetrad and NAD-binding motif of the extended SDR, and is related to more specifically defined epimerases such as UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), which catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup includes Escherichia coli 055:H7 Gne, a UDP-GlcNAc 4-epimerase, essential for O55 antigen synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.53262e-108
NZ_CP021844.1\|WP_000699721.1\|1965505_1966729_+\|colanic-acid-biosynthesis-fucosyltransferase-WcaI	gnl\|CDD\|188522	TIGR04007, wcaI, colanic acid biosynthesis glycosyl transferase WcaI. This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.	0
NZ_CP021844.1\|WP_000862654.1\|1974301_1975522_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaL	gnl\|CDD\|188520	TIGR04005, wcaL, colanic acid biosynthesis glycosyltransferase WcaL. This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.	0
NZ_CP021844.1\|WP_001298845.1\|1965029_1965509_+\|GDP-mannose-mannosyl-hydrolase	gnl\|CDD\|237966	PRK15434, PRK15434, GDP-mannose mannosyl hydrolase.	3.22213e-118
NZ_CP021844.1\|WP_060684448.1\|1983128_1984688_+\|O51-family-O-antigen-flippase	gnl\|CDD\|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.22907e-06
NZ_CP021844.1\|WP_000183060.1\|1978322_1979216_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalF	gnl\|CDD\|182252	PRK10122, PRK10122, UTP--glucose-1-phosphate uridylyltransferase GalF.	0
NZ_CP021844.1\|WP_033870517.1\|1979587_1980673_+\|dTDP-glucose-4,6-dehydratase	gnl\|CDD\|236649	PRK10084, PRK10084, dTDP-glucose 4,6 dehydratase; Provisional.	0
NZ_CP021844.1\|WP_000048190.1\|1962937_1964059_+\|GDP-mannose-4,6-dehydratase	gnl\|CDD\|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP021844.1\|WP_000043590.1\|1964061_1965027_+\|GDP-L-fucose-synthase	gnl\|CDD\|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NZ_CP021844.1\|WP_044863830.1\|1980672_1981572_+\|dTDP-4-dehydrorhamnose-reductase	gnl\|CDD\|182184	PRK09987, PRK09987, dTDP-4-dehydrorhamnose reductase; Provisional.	0
NZ_CP021844.1\|WP_000770774.1\|1973024_1974305_+\|colanic-acid-biosynthesis-pyruvyl-transferase-WcaK	gnl\|CDD\|188521	TIGR04006, wcaK, colanic acid biosynthesis pyruvyl transferase WcaK. This gene is the pyruvyl transferase involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.	0
NZ_CP021844.1\|WP_001153551.1\|1962362_1962911_+\|colanic-acid-biosynthesis-acetyltransferase-WcaF	gnl\|CDD\|188523	TIGR04008, WcaF, colanic acid biosynthesis acetyltransferase WcaF. This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species. This acetyltransferase is believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit).	2.90698e-131
NZ_CP021844.1\|WP_033870520.1\|1982512_1983055_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl\|CDD\|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	2.97067e-108
NZ_CP021844.1\|WP_000927041.1\|1961600_1962347_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaE	gnl\|CDD\|182218	PRK10063, PRK10063, colanic acid biosynthesis glycosyltransferase WcaE.	0
NZ_CP021844.1\|WP_033870519.1\|1981629_1982508_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|185377	PRK15480, PRK15480, glucose-1-phosphate thymidylyltransferase RfbA; Provisional.	0
NZ_CP021844.1\|WP_001355594.1\|1968448_1969819_+\|phosphomannomutase-CpsG	gnl\|CDD\|185312	PRK15414, PRK15414, phosphomannomutase.	0
NZ_CP021844.1\|WP_000079280.1\|1966731_1968168_+\|mannose-1-phosphate-guanyltransferase	gnl\|CDD\|185357	PRK15460, cpsB, mannose-1-phosphate guanyltransferase; Provisional.	0
NZ_CP021844.1\|WP_000058435.1\|1971269_1972748_+\|M-antigen-undecaprenyl-disphosphate-flippase	gnl\|CDD\|236697	PRK10459, PRK10459, MOP flippase family protein.	0

>NZ_CP021844.1|WP_000058435.1|1971269_1972748_+|M-antigen-undecaprenyl-disphosphate-flippase
MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLLTVSLVIIALADTLSDFGIANSIIQRKEISHLELTTLYWLNVGLGIVVCVAVFLLSDLIGDVLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTFTVVSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTADSIINYLNTNLSTLVLARILGAGVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQDDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKWNSIIPVLQLLCVVGLLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIVIGGQMAGAIGVTLGFLLVQIINTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTLGVSYALGIVLKGQLALGMLLAVQIAAGVLAFVVMIVLSRHPLVVEVKRQFCRSEKMKMLLRAG
>NZ_CP021844.1|WP_000183133.1|1969873_1971268_+|undecaprenyl-phosphate-glucose-phosphotransferase
MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSVIFSAGLVAFNNDFDTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLMESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVVPLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLTSPGPVIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY
>NZ_CP021844.1|WP_001355594.1|1968448_1969819_+|phosphomannomutase-CpsG
MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLFGYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKEKTLGELVRDRMAAFPASGEINSKLAQPVEAINRVEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEARTRTLLTLLNE
>NZ_CP021844.1|WP_000079280.1|1966731_1968168_+|mannose-1-phosphate-guanyltransferase
MAQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAAKRHSPESDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDTVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAIDPDLDFIRVDEEAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFADRYGRV
>NZ_CP021844.1|WP_000699721.1|1965505_1966729_+|colanic-acid-biosynthesis-fucosyltransferase-WcaI
MKILVYGINYSPELTGIGKYTGEMVEWLAAQGHEVRVITAPPYYPQWQVGENYSAWRYKREEGAATVWRCPLYVPKQPSTLKRLLHLGSFAVSSFFPLMAQRRWKPDRIIGVVPTLFCTPGMRLLAKLSGARTVLHIQDYEVDAMLGLGLAGKGKGGKVAQLATAFERSGLHNVDNVSTISRSMMNKAIEKGVAAENVIFFPNWSEIARFQHVADADVDALRNQLDLPDNKKIILYSGNIGEKQGLENVIEAADRLRDEPLIFAIVGQGGGKARLEKMAQQRGLRNMQFFPLQSYDALPALLKMGDCHLVVQKRGAADAVLPSKLTNILAVGGNAVITAEAHTELGQLCETFPGIAVCVEPESVEALVAGIRQALLLPKHNTVAREYAERTLDKENVLRQFINDIRG
>NZ_CP021844.1|WP_001298845.1|1965029_1965509_+|GDP-mannose-mannosyl-hydrolase
MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGLRLPITAGQFYGVWQHFYDDNFSGTDFTTHYVVLGFRFRVAEEDLILPDEQHDDYRWLTPDALLASNDVHANSRAYFLAEKRAGVPGL
>NZ_CP021844.1|WP_000043590.1|1964061_1965027_+|GDP-L-fucose-synthase
MSKQRIFIAGHRGMVGSAIKRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG
>NZ_CP021844.1|WP_000048190.1|1962937_1964059_+|GDP-mannose-4,6-dehydratase
MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES
>NZ_CP021844.1|WP_001153551.1|1962362_1962911_+|colanic-acid-biosynthesis-acetyltransferase-WcaF
MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRAFLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDDVNLYTLGEITIGAHSVISQKSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGNGTVVGARSSVFKSLPANVVCRGNPAVVIRERVETE
>NZ_CP021844.1|WP_000927041.1|1961600_1962347_+|colanic-acid-biosynthesis-glycosyltransferase-WcaE
MLLSIITVAFRNLEGIVKTHASLAHLAQADDISFEWIVVDGGSNDGTREYLENLNGIYNLRFVSEPDNGIYDAMNKGIAMAQGKFALFLNSGDIFHQDAANFVRKLKMQKDNVMITGDALLDFGDGHKIKRSAKPGWYIYHSLPASHQAIFFPVSGLKKWRYDLEYKVSSDYALAAKMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQILHVPGFWAELSWHLRQRTTSKTKALYNKS
>NZ_CP021844.1|WP_000770774.1|1973024_1974305_+|colanic-acid-biosynthesis-pyruvyl-transferase-WcaK
MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPVSSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNIAIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCSFMAKKPLFMIGHSVGPFQDEQFNQLANYVFDHCDALILRESVSLDLMKRSNITTAKVEHGVDTAWLVDHHTEDFTASYAVQHWLDVAAQQKTVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQVIALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGTRLHSAIISMNFATPAIAINYEHKSAGIMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQLPALNARLSEAVSRERQTGMQMVQSVLERIGEAK
>NZ_CP021844.1|WP_000862654.1|1974301_1975522_+|colanic-acid-biosynthesis-glycosyltransferase-WcaL
MKVGFFLLKFPLSSETFVLNQITAFIDMGFEVEIVALQKGDTQNTHAAWTKYNLAARTRWLQDEPTGKVAKLRHRASQTLRGIHRKNTWQALNLKRYGAESRNLILSAICGQVATPFHADVFIAHFGPAGVTAAKLRELGVIRGKIATIFHGIDISSREVLNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTRFSPRPVKAPATPLEIISVARLTEKKGLHVAIEACRQLKELGVAFRYRILGIGPWERRLRTLIEQYQLEDVVEMPGFKPSHEVKAMLDDADVFLLPSVTGADGDMEGIPVALMEAMAVGIPVVSTLHSGIPELVEADKSGWLVPENDARALAQRLAAFSQLDTDELAPVIKRAREKVEHDFNQQVINRELASLLQAL
>NZ_CP021844.1|WP_001116129.1|1975532_1976927_+|colanic-acid-biosynthesis-protein-WcaM
MPFKTLSRRTFLTASSALAFLHTPFARALPARQSVNINDYNPHDWIASFKQAFSEGQTVVVPAGLVCDNINTGIFIPPGKTLHILGSLRGNGRGRFVLQDGSQVTGGEGGGMHNITLDVRGSDCTIKGLAMSGFGPVMQIYIGGKNKRVMRNLTIDNLTVSHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILISDHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGTYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRINHHIVNVEKINFRLPERRE
>NZ_CP021844.1|WP_053882441.1|1977084_1978080_+|SDR-family-oxidoreductase
MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQIGDVRDQQALDQALVGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVKNIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIRPTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVTVGYEVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAVSSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE
>NZ_CP021844.1|WP_000183060.1|1978322_1979216_+|UTP--glucose-1-phosphate-uridylyltransferase-GalF
MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKGIEKLLSE
>NZ_CP021844.1|WP_033870517.1|1979587_1980673_+|dTDP-glucose-4,6-dehydratase
MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLADVSDSERYVFEHADICDAAAMARIFALHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPHADEVNNTEELPLFTETTAYAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHARALYTVVIEGKAGETYNIGGHNEKKNIDVVLTICDLLDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWYLSNTKWVNNVKSGAYQSWIEQNYEGRQ
>NZ_CP021844.1|WP_044863830.1|1980672_1981572_+|dTDP-4-dehydrorhamnose-reductase
MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPEGVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHYSTDYVFPGNGDTPWLETDTTAPLNVYGETKLAGEKALQKHCPKHLIFRTSWVYAGKGNNFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVASGTTTWHDYAALVFEEARKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNELFTTTAI
>NZ_CP021844.1|WP_033870519.1|1981629_1982508_+|glucose-1-phosphate-thymidylyltransferase-RfbA
MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLMDAAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISLEEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGHLSVAMMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQVKVLAQPLKKNAYGKYLLKMIEGY
>NZ_CP021844.1|WP_033870520.1|1982512_1983055_+|dTDP-4-dehydrorhamnose-3,5-epimerase
MNVIKTEIPDVLIFEPKVFGDERGFFMESFNQKVFEEAVGRKVEFVQDNHSKSNKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVNLSAANKRQLWIPEGFAHGFLSLTDNTEFLYKTNNFYNRNYERCLKFDDIELSIKWPIGDETELIVSEKDMLGNIFSKL
>NZ_CP021844.1|WP_060684448.1|1983128_1984688_+|O51-family-O-antigen-flippase
MRASPFFRSVKYGIVFSLVIMILTFIVRQCIINSFGENLTGYYLLINQLVGYLNLAELGLTTASVYLLFKPLNSENKYDIVGYFYIIHRIFKFIASAILIIGLTLSFIMPYLVKDNINWHDIYIPWVFYVIATALSYFYSAETVLLTASEKLYIVRIVNGLARVITFLIQIVVLKNGGGFIIFSALEILYVLIQYILFRYYVLKLYGTYLYSKTTLSKELPLIKQTIIKEIKKTFIHKLSGVMIFNTDYIIISIFIGLSTITIYSSYLMFIQASAIIIGTIVSPLGAYIGNFLQRTDSNLTYLKFNSINTIFFLLASIGCIIYNNISTPFVQLWMGKDIIFSQDIVALLAVNFFCLVARSAVDIFKVAYGYMSDIHLPIIEGTLNLIISLALVNFYGVKGVIYGTICSNVIIIMLARPWYLYKEAFNLCTIDFIKDHIQLWVISLMILTTLLSGRVNDMYTLFEKYLMNNWDVSNKLIEQLLTHSLFLALSTIFVVIIYIIVTPKNCLASVKILTNKGL

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Crispr_ID: NZ_CP021844_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_6

2411600-2411723

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_6

>merge|NZ_CP021844|6|2411600-2411723|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP021844|6|6|2411600-2411723|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_000493947.1\|2414922_2415564_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP021844.1\|WP_000212678.1\|2411159_2411465_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP021844.1\|WP_000102278.1\|2420619_2420709_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP021844.1\|WP_000098896.1\|2415603_2416752_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP021844.1\|WP_021577543.1\|2404334_2406437_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP021844.1\|WP_021577538.1\|2417042_2418254_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP021844.1\|WP_088172416.1\|2408605_2409418_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP021844.1\|WP_000528342.1\|2403022_2403232_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP021844.1\|WP_001349911.1\|2407151_2407820_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP021844.1\|WP_001070230.1\|2403687_2404314_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP021844.1\|WP_000716939.1\|2409429_2411034_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP021844.1\|WP_000701040.1\|2420874_2422044_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP021844.1\|WP_088172417.1\|2406440_2407088_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP021844.1\|WP_001295403.1\|2401053_2402466_-\|pyruvate-kinase-I	unknown	unknown	gnl\|CDD\|181699
NZ_CP021844.1\|WP_001069978.1\|2407816_2408602_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP021844.1\|WP_000007283.1\|2422189_2422771_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP021844.1\|WP_001174937.1\|2413334_2414708_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP021844.1\|WP_000190982.1\|2419295_2420321_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP021844.1\|WP_021577539.1\|2412037_2413294_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP021844.1\|WP_000269493.1\|2418366_2419299_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_000493947.1\|2414922_2415564_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP021844.1\|WP_000212678.1\|2411159_2411465_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.20156e-64
NZ_CP021844.1\|WP_000701040.1\|2420874_2422044_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
NZ_CP021844.1\|WP_000098896.1\|2415603_2416752_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP021844.1\|WP_021577543.1\|2404334_2406437_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP021844.1\|WP_021577538.1\|2417042_2418254_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP021844.1\|WP_088172416.1\|2408605_2409418_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	4.59708e-174
NZ_CP021844.1\|WP_000528342.1\|2403022_2403232_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP021844.1\|WP_001349911.1\|2407151_2407820_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	7.32003e-76
NZ_CP021844.1\|WP_001070230.1\|2403687_2404314_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP021844.1\|WP_000716939.1\|2409429_2411034_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP021844.1\|WP_088172417.1\|2406440_2407088_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	1.21212e-121
NZ_CP021844.1\|WP_001295403.1\|2401053_2402466_-\|pyruvate-kinase-I	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP021844.1\|WP_001069978.1\|2407816_2408602_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	3.21778e-163
NZ_CP021844.1\|WP_000007283.1\|2422189_2422771_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP021844.1\|WP_001174937.1\|2413334_2414708_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP021844.1\|WP_000190982.1\|2419295_2420321_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP021844.1\|WP_021577539.1\|2412037_2413294_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP021844.1\|WP_000269493.1\|2418366_2419299_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0

>NZ_CP021844.1|WP_000212678.1|2411159_2411465_-|monooxygenase
MATLLQLHFSFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP021844.1|WP_000716939.1|2409429_2411034_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARKQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP021844.1|WP_088172416.1|2408605_2409418_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAVQIASMGYSVRIGSVGFNSHIGSSGERAQVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>NZ_CP021844.1|WP_001069978.1|2407816_2408602_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGEKIYLYSKAVRLWHWSNALLFVLLLASGLINHFAMLGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP021844.1|WP_001349911.1|2407151_2407820_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP021844.1|WP_088172417.1|2406440_2407088_+|YdhW-family-putative-oxidoreductase-system-protein
MGEMNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLVNIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRALAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAMLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP021844.1|WP_021577543.1|2404334_2406437_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPRDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPA
>NZ_CP021844.1|WP_001070230.1|2403687_2404314_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP021844.1|WP_000528342.1|2403022_2403232_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP021844.1|WP_001295403.1|2401053_2402466_-|pyruvate-kinase-I
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP021844.1|WP_021577539.1|2412037_2413294_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVTTGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKANDTLLAGGTMNNLGGEDSDTIVENGAIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFSIGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQISAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP021844.1|WP_001174937.1|2413334_2414708_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLAAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
>NZ_CP021844.1|WP_000493947.1|2414922_2415564_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP021844.1|WP_000098896.1|2415603_2416752_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP021844.1|WP_021577538.1|2417042_2418254_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MLPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHSNAEVAHSESH
>NZ_CP021844.1|WP_000269493.1|2418366_2419299_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP021844.1|WP_000190982.1|2419295_2420321_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP021844.1|WP_000102278.1|2420619_2420709_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP021844.1|WP_000701040.1|2420874_2422044_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP021844.1|WP_000007283.1|2422189_2422771_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Crispr_ID: NZ_CP021844_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_7

3095697-3095788

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_7

>merge|NZ_CP021844|7|3095697-3095788|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGATCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP021844|7|7|3095697-3095788|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGATCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_000024560.1\|3101060_3101366_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP021844.1\|WP_001325510.1\|3094254_3095583_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP021844.1\|WP_001120119.1\|3105961_3106654_+\|two-component-system-response-regulator-TorR	unknown	unknown	gnl\|CDD\|182711
NZ_CP021844.1\|WP_021577293.1\|3098627_3099881_-\|YccE-family-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP021844.1\|WP_021577295.1\|3092328_3093129_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP021844.1\|WP_001345643.1\|3091230_3091923_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP021844.1\|WP_001151437.1\|3096211_3096808_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP021844.1\|WP_000420641.1\|3100140_3101061_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP021844.1\|WP_001044306.1\|3097093_3098335_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP021844.1\|WP_000191701.1\|3089213_3089852_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP021844.1\|WP_001301233.1\|3090139_3091231_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP021844.1\|WP_001230244.1\|3104659_3105832_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992
NZ_CP021844.1\|WP_021577291.1\|3102113_3104660_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP021844.1\|WP_000939660.1\|3084948_3085155_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021844.1\|WP_021577297.1\|3085212_3089175_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP021844.1\|WP_021577292.1\|3101517_3102117_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP021844.1\|WP_001143120.1\|3096828_3097056_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP021844.1\|WP_001126784.1\|3091934_3092321_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP021844.1\|WP_021577294.1\|3093138_3093729_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP021844.1\|WP_001028095.1\|3093739_3094234_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_000024560.1\|3101060_3101366_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	5.75956e-65
NZ_CP021844.1\|WP_001325510.1\|3094254_3095583_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP021844.1\|WP_001120119.1\|3105961_3106654_+\|two-component-system-response-regulator-TorR	gnl\|CDD\|182711	PRK10766, PRK10766, two-component system response regulator TorR.	1.50001e-137
NZ_CP021844.1\|WP_021577293.1\|3098627_3099881_-\|YccE-family-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP021844.1\|WP_021577295.1\|3092328_3093129_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	2.46007e-139
NZ_CP021844.1\|WP_001345643.1\|3091230_3091923_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	2.60527e-169
NZ_CP021844.1\|WP_001151437.1\|3096211_3096808_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	8.51484e-133
NZ_CP021844.1\|WP_000420641.1\|3100140_3101061_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP021844.1\|WP_001044306.1\|3097093_3098335_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP021844.1\|WP_000191701.1\|3089213_3089852_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	1.3356e-153
NZ_CP021844.1\|WP_001301233.1\|3090139_3091231_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP021844.1\|WP_001230244.1\|3104659_3105832_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0
NZ_CP021844.1\|WP_021577291.1\|3102113_3104660_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP021844.1\|WP_021577297.1\|3085212_3089175_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP021844.1\|WP_021577292.1\|3101517_3102117_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	1.24745e-81
NZ_CP021844.1\|WP_001143120.1\|3096828_3097056_+\|hypothetical-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP021844.1\|WP_001126784.1\|3091934_3092321_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	2.00775e-84
NZ_CP021844.1\|WP_021577294.1\|3093138_3093729_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	2.32218e-129
NZ_CP021844.1\|WP_001028095.1\|3093739_3094234_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	3.76111e-106

>NZ_CP021844.1|WP_001325510.1|3094254_3095583_+|pyrimidine-utilization-transport-protein-G
MAMFGLPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASGFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP
>NZ_CP021844.1|WP_001028095.1|3093739_3094234_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
>NZ_CP021844.1|WP_021577294.1|3093138_3093729_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARIWFTSSPQLAEETAFRNSSMQAAYLIIACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
>NZ_CP021844.1|WP_021577295.1|3092328_3093129_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSITQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAAHAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHAVRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP021844.1|WP_001126784.1|3091934_3092321_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINETYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP021844.1|WP_001345643.1|3091230_3091923_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFVQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>NZ_CP021844.1|WP_001301233.1|3090139_3091231_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPVLTQEVA
>NZ_CP021844.1|WP_000191701.1|3089213_3089852_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
>NZ_CP021844.1|WP_021577297.1|3085212_3089175_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANEGDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPCEVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPSGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQIMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSTVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP021844.1|WP_000939660.1|3084948_3085155_-|hypothetical-protein
MLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NZ_CP021844.1|WP_001151437.1|3096211_3096808_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP021844.1|WP_001143120.1|3096828_3097056_+|hypothetical-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP021844.1|WP_001044306.1|3097093_3098335_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAATVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECPPPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDADGFCPMDKFDSVLNEAVK
>NZ_CP021844.1|WP_021577293.1|3098627_3099881_-|YccE-family-protein
MGNIHGISCTANNYLKQAWNDIKNEYEKNKTYSITLFENTLVCFIRLYKEIRRQQAEDYIPCLECDSLEKEFEEIQNDNDLSLFMKTLRTNDKQIYSGVSGGITYTIQYVEDVDIVRVSLPGRGSESITDFKGYYWYGFMEYIENINACDDVYSDYCFDDENISVQPEWINTPGISDLDSGIDLSGISFIQSEINKTYGLKYAPVDGDGYCLLRAILVLKQHDYSWALGSHKTQKEVYEEFIKIVDKQTIEALVDAAFYDLREDVKTLFGVDLQSDNKIQGVGSPMSWSFLFFKKQFIDSCLNKEKCILHLPEFIFNDNKNLLALDTDTSDRIKAVKNFLAVLSDSICSLFIVNSNVASISLGNESFSTDEDLEYGYLINTGNHYDVYLPPELFAQAYKLNNKEMNAQLDYLNRYAI
>NZ_CP021844.1|WP_000420641.1|3100140_3101061_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFSRQFQHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP021844.1|WP_000024560.1|3101060_3101366_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
>NZ_CP021844.1|WP_021577292.1|3101517_3102117_-|molecular-chaperone-TorD
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLTAAVDELENRVATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALRQWLPEFASRCRQYDSFGFYAALSQLLLVLVEGDHQNR
>NZ_CP021844.1|WP_021577291.1|3102113_3104660_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATEAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQTYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKL
>NZ_CP021844.1|WP_001230244.1|3104659_3105832_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>NZ_CP021844.1|WP_001120119.1|3105961_3106654_+|two-component-system-response-regulator-TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPYTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC

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Crispr_ID: NZ_CP021844_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_8

3235742-3235890

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTACGGCAGTGAAC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP021844_8

>merge|NZ_CP021844|8|3235742-3235890|CRISPRCasFinder,PILER-CR
CATTTTATCTGCCTGTACGGCAGTGAACATGGTGGGCGGGTGGAGTATGTTACCAGTGAATTTCTAAGCTGCCTGTACGGCAGTGAACGTTCGCTGCAACCGCTAGCCAAGACGGTAGGTTTTTCTAAGCTGCCTGTACGGCAGTGAAC

>NZ_CP021844|8|8|3235742-3235890|CRISPRCasFinder
CATTTTATCTGCCTGTACGGCAGTGAAC	ATGGTGGGCGGGTGGAGTATGTTACCAGTGAA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GTTCGCTGCAACCGCTAGCCAAGACGGTAGGTT
TTTCTAAGCTGCCTGTACGGCAGTGAAC

>NZ_CP021844|8|3|3235750-3235890|PILER-CR
CTGCCTGTACGGCAGTGAACATGGTGGG	CGGGTGGAGTATGTTACCAGTGAATTTCTAAG
CTGCCTGTACGGCAGTGAACGTTCGCTG	CAACCGCTAGCCAAGACGGTAGGTTTTTCTAAG
CTGCCTGTACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_001295343.1\|3223523_3224135_-\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NZ_CP021844.1\|WP_000488716.1\|3245597_3246293_+\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NZ_CP021844.1\|WP_021577186.1\|3232385_3234107_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
NZ_CP021844.1\|WP_000537432.1\|3229530_3230496_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NZ_CP021844.1\|WP_001322270.1\|3242560_3243517_+\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
NZ_CP021844.1\|WP_000746460.1\|3241294_3242410_-\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NZ_CP021844.1\|WP_088172361.1\|3243513_3245172_-\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NZ_CP021844.1\|WP_000491136.1\|3246749_3247649_+\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287
NZ_CP021844.1\|WP_000410785.1\|3239054_3239279_+\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NZ_CP021844.1\|WP_000886683.1\|3220786_3222079_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP021844.1\|WP_000188180.1\|3239351_3241298_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NZ_CP021844.1\|WP_000934041.1\|3236104_3238381_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NZ_CP021844.1\|WP_000520781.1\|3238411_3238732_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP021844.1\|WP_000458817.1\|3247792_3249445_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NZ_CP021844.1\|WP_001043587.1\|3230618_3232385_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NZ_CP021844.1\|WP_001241678.1\|3234148_3234853_+\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP021844.1\|WP_088172362.1\|3224289_3228357_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NZ_CP021844.1\|WP_000228473.1\|3228491_3228986_-\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
NZ_CP021844.1\|WP_000067755.1\|3222169_3223513_-\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP021844.1\|WP_001040187.1\|3235137_3235356_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_001295343.1\|3223523_3224135_-\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
NZ_CP021844.1\|WP_000488716.1\|3245597_3246293_+\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	7.82992e-144
NZ_CP021844.1\|WP_021577186.1\|3232385_3234107_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP021844.1\|WP_000537432.1\|3229530_3230496_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NZ_CP021844.1\|WP_001322270.1\|3242560_3243517_+\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	1.29444e-131
NZ_CP021844.1\|WP_000746460.1\|3241294_3242410_-\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NZ_CP021844.1\|WP_088172361.1\|3243513_3245172_-\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NZ_CP021844.1\|WP_000491136.1\|3246749_3247649_+\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	4.57772e-118
NZ_CP021844.1\|WP_000410785.1\|3239054_3239279_+\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NZ_CP021844.1\|WP_000886683.1\|3220786_3222079_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP021844.1\|WP_000188180.1\|3239351_3241298_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NZ_CP021844.1\|WP_000934041.1\|3236104_3238381_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NZ_CP021844.1\|WP_000520781.1\|3238411_3238732_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
NZ_CP021844.1\|WP_000458817.1\|3247792_3249445_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NZ_CP021844.1\|WP_001043587.1\|3230618_3232385_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP021844.1\|WP_001241678.1\|3234148_3234853_+\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	3.45002e-139
NZ_CP021844.1\|WP_088172362.1\|3224289_3228357_-\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NZ_CP021844.1\|WP_000228473.1\|3228491_3228986_-\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
NZ_CP021844.1\|WP_000067755.1\|3222169_3223513_-\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP021844.1\|WP_001040187.1\|3235137_3235356_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49

>NZ_CP021844.1|WP_001040187.1|3235137_3235356_+|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NZ_CP021844.1|WP_001241678.1|3234148_3234853_+|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
>NZ_CP021844.1|WP_021577186.1|3232385_3234107_+|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAVILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NZ_CP021844.1|WP_001043587.1|3230618_3232385_+|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI
>NZ_CP021844.1|WP_000537432.1|3229530_3230496_+|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NZ_CP021844.1|WP_000228473.1|3228491_3228986_-|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NZ_CP021844.1|WP_088172362.1|3224289_3228357_-|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDEEDITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPSQPTVAWQPEPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFTLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQQVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NZ_CP021844.1|WP_001295343.1|3223523_3224135_-|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NZ_CP021844.1|WP_000067755.1|3222169_3223513_-|replication-associated-recombination-protein-A
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NZ_CP021844.1|WP_000886683.1|3220786_3222079_-|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
>NZ_CP021844.1|WP_000934041.1|3236104_3238381_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NZ_CP021844.1|WP_000520781.1|3238411_3238732_-|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NZ_CP021844.1|WP_000410785.1|3239054_3239279_+|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NZ_CP021844.1|WP_000188180.1|3239351_3241298_-|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGITLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NZ_CP021844.1|WP_000746460.1|3241294_3242410_-|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NZ_CP021844.1|WP_001322270.1|3242560_3243517_+|DUF535-domain-containing-protein
MNMSQLTERTFTSSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG
>NZ_CP021844.1|WP_088172361.1|3243513_3245172_-|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDRRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NZ_CP021844.1|WP_000488716.1|3245597_3246293_+|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>NZ_CP021844.1|WP_000491136.1|3246749_3247649_+|L-lysine-exporter-LysO
MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NZ_CP021844.1|WP_000458817.1|3247792_3249445_+|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA

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Crispr_ID: NZ_CP021844_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_9

4038300-4038406

Orphan

Consensus_repeat	Method
CCCTCTCCCTGCGGGAGAGGGTTAGGGTGAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_9

>merge|NZ_CP021844|9|4038300-4038406|CRISPRCasFinder
CCCTCTCCCTGCGGGAGAGGGTTAGGGTGAGGGGGCAAACCTGCGCCCTGGTCAACACCGCGCTCGATCGGTTCCCTCTCCCTCCGGGAGAGGGTTAGGGTGAGGGG

>NZ_CP021844|9|9|4038300-4038406|CRISPRCasFinder
CCCTCTCCCTGCGGGAGAGGGTTAGGGTGAGGGG	GCAAACCTGCGCCCTGGTCAACACCGCGCTCGATCGGTT
CCCTCTCCCTCCGGGAGAGGGTTAGGGTGAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_033815266.1\|4036427_4036706_+\|flagellar-biosynthesis-anti-sigma-factor-FlgM	unknown	unknown	gnl\|CDD\|274802
NZ_CP021844.1\|WP_123008325.1\|4038464_4040909_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|366154
NZ_CP021844.1\|WP_088172312.1\|4043223_4044561_-\|flagellar-protein-export-ATPase-FliI	unknown	unknown	gnl\|CDD\|180875
NZ_CP021844.1\|WP_123008323.1\|4035192_4035528_-\|flagellar-basal-body-rod-protein-FlgB	unknown	unknown	gnl\|CDD\|183682
NZ_CP021844.1\|WP_088172317.1\|4030998_4031784_-\|flagellar-basal-body-rod-protein-FlgG	unknown	unknown	gnl\|CDD\|183687
NZ_CP021844.1\|WP_088172311.1\|4046255_4047911_-\|flagellar-M-ring-protein-FliF	unknown	unknown	gnl\|CDD\|235957
NZ_CP021844.1\|WP_033815268.1\|4034758_4035190_-\|flagellar-basal-body-rod-protein-FlgC	unknown	unknown	gnl\|CDD\|180702
NZ_CP021844.1\|WP_088172313.1\|4042786_4043221_-\|flagellar-export-protein-FliJ	unknown	unknown	gnl\|CDD\|131526
NZ_CP021844.1\|WP_000151519.1\|4044553_4045264_-\|flagellar-assembly-protein-H	unknown	unknown	gnl\|CDD\|237372
NZ_CP021844.1\|WP_033815269.1\|4034045_4034759_-\|flagellar-hook-capping-protein	unknown	unknown	gnl\|CDD\|181996
NZ_CP021844.1\|WP_033815265.1\|4036718_4037147_+\|flagellar-protein-FlgN	unknown	unknown	gnl\|CDD\|377465
NZ_CP021844.1\|WP_033815270.1\|4032699_4033902_-\|flagellar-basal-body-protein-FlaE	unknown	unknown	gnl\|CDD\|235862
NZ_CP021844.1\|WP_123008324.1\|4037274_4038204_+\|lysine-N-methylase	unknown	unknown	unknown
NZ_CP021844.1\|WP_085008556.1\|4041309_4042386_+\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NZ_CP021844.1\|WP_001293120.1\|4045267_4046278_-\|flagellar-motor-switch-protein-FliG	unknown	unknown	gnl\|CDD\|235958
NZ_CP021844.1\|WP_033815271.1\|4031962_4032700_-\|flagellar-basal-body-rod-protein-FlgF	unknown	unknown	gnl\|CDD\|183642
NZ_CP021844.1\|WP_000029084.1\|4047915_4048257_-\|flagellar-hook-basal-body-complex-protein-FliE	unknown	unknown	gnl\|CDD\|376721
NZ_CP021844.1\|WP_033815267.1\|4035609_4036347_+\|flagellar-basal-body-P-ring-formation-protein-FlgA	unknown	unknown	gnl\|CDD\|235863
NZ_CP021844.1\|WP_088172310.1\|4048271_4049258_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP021844.1\|WP_085008558.1\|4042379_4042784_-\|adenylyltransferase/cytidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|173922

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_033815266.1\|4036427_4036706_+\|flagellar-biosynthesis-anti-sigma-factor-FlgM	gnl\|CDD\|274802	TIGR03824, FlgM_jcvi, flagellar biosynthesis anti-sigma factor FlgM. FlgM interacts with and inhibits the alternative sigma factor sigma(28) FliA. The C-terminus of FlgM contains the sigma(28)-binding domain.	4.70337e-08
NZ_CP021844.1\|WP_123008325.1\|4038464_4040909_+\|glycosyltransferase	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	5.21673e-16
NZ_CP021844.1\|WP_088172312.1\|4043223_4044561_-\|flagellar-protein-export-ATPase-FliI	gnl\|CDD\|180875	PRK07196, fliI, flagellar protein export ATPase FliI.	0
NZ_CP021844.1\|WP_123008323.1\|4035192_4035528_-\|flagellar-basal-body-rod-protein-FlgB	gnl\|CDD\|183682	PRK12685, flgB, flagellar basal body rod protein FlgB; Reviewed.	3.93988e-47
NZ_CP021844.1\|WP_088172317.1\|4030998_4031784_-\|flagellar-basal-body-rod-protein-FlgG	gnl\|CDD\|183687	PRK12693, flgG, flagellar basal body rod protein FlgG; Provisional.	3.4176e-140
NZ_CP021844.1\|WP_088172311.1\|4046255_4047911_-\|flagellar-M-ring-protein-FliF	gnl\|CDD\|235957	PRK07193, fliF, flagellar MS-ring protein; Reviewed.	0
NZ_CP021844.1\|WP_033815268.1\|4034758_4035190_-\|flagellar-basal-body-rod-protein-FlgC	gnl\|CDD\|180702	PRK06802, flgC, flagellar basal body rod protein FlgC; Reviewed.	1.87022e-83
NZ_CP021844.1\|WP_088172313.1\|4042786_4043221_-\|flagellar-export-protein-FliJ	gnl\|CDD\|131526	TIGR02473, conserved_hypothetical_protein, flagellar export protein FliJ. Members of this family are the FliJ protein found, in nearly every case, in the midst of other flagellar biosynthesis genes in bacgterial genomes. Typically the fliJ gene is found adjacent to the gene for the flagellum-specific ATPase FliI. Sequence scoring in the gray zone between trusted and noise cutoffs include both probable FliJ proteins and components of bacterial type III secretion systems.	2.17634e-08
NZ_CP021844.1\|WP_000151519.1\|4044553_4045264_-\|flagellar-assembly-protein-H	gnl\|CDD\|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	1.27477e-109
NZ_CP021844.1\|WP_033815269.1\|4034045_4034759_-\|flagellar-hook-capping-protein	gnl\|CDD\|181996	PRK09619, flgD, flagellar hook assembly protein FlgD.	1.1987e-60
NZ_CP021844.1\|WP_033815265.1\|4036718_4037147_+\|flagellar-protein-FlgN	gnl\|CDD\|377465	pfam05130, FlgN, FlgN protein. This family includes the FlgN protein and export chaperone involved in flagellar synthesis.	6.83231e-12
NZ_CP021844.1\|WP_033815270.1\|4032699_4033902_-\|flagellar-basal-body-protein-FlaE	gnl\|CDD\|235862	PRK06803, flgE, flagellar basal body protein FlaE.	1.01457e-163
NZ_CP021844.1\|WP_033815271.1\|4031962_4032700_-\|flagellar-basal-body-rod-protein-FlgF	gnl\|CDD\|183642	PRK12640, flgF, flagellar basal body rod protein FlgF; Reviewed.	5.01893e-118
NZ_CP021844.1\|WP_085008556.1\|4041309_4042386_+\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	7.51706e-51
NZ_CP021844.1\|WP_001293120.1\|4045267_4046278_-\|flagellar-motor-switch-protein-FliG	gnl\|CDD\|235958	PRK07194, fliG, flagellar motor switch protein G; Reviewed.	1.10696e-177
NZ_CP021844.1\|WP_000029084.1\|4047915_4048257_-\|flagellar-hook-basal-body-complex-protein-FliE	gnl\|CDD\|376721	pfam02049, FliE, Flagellar hook-basal body complex protein FliE.	1.37988e-15
NZ_CP021844.1\|WP_033815267.1\|4035609_4036347_+\|flagellar-basal-body-P-ring-formation-protein-FlgA	gnl\|CDD\|235863	PRK06804, flgA, flagellar basal body P-ring formation protein FlgA.	2.33247e-58
NZ_CP021844.1\|WP_088172310.1\|4048271_4049258_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.09583e-122
NZ_CP021844.1\|WP_085008558.1\|4042379_4042784_-\|adenylyltransferase/cytidyltransferase-family-protein	gnl\|CDD\|173922	cd02171, G3P_Cytidylyltransferase, glycerol-3-phosphate cytidylyltransferase. Glycerol-3-phosphate cytidylyltransferase,(CDP-glycerol pyrophosphorylase). Glycerol-3-phosphate cytidyltransferase acts in pathways of teichoic acid biosynthesis. Teichoic acids are substituted polymers, linked by phosphodiester bonds, of glycerol, ribitol, etc. An example is poly(glycerol phosphate), the major teichoic acid of the Bacillus subtilis cell wall. Most, but not all, species encoding proteins in this family are Gram-positive bacteria. A closely related protein assigned a different function experimentally is a human ethanolamine-phosphate cytidylyltransferase.	4.66356e-48

>NZ_CP021844.1|WP_123008324.1|4037274_4038204_+|lysine-N-methylase
MSFIECYEPEYVRNFMTQHPGSPLYVRKVWKNEIRLSLMLTEPESCEAVLNDASAFDLQLTYRPVEDNAAELSARDAIVNQVILSTLTLPDLTPELSLYAVGILLSRASKMPGRDGDILARLTTLPQALADHAQKGTLQAQFAQLPPVPQLARQLMMLLGGCAFDWSILPESPRKTFLPLQMPLLTLHDANSEALLQQQLQTQWQTTWQQHFATAPWMMHNWLIYRVYHEVIGQTDGADYCPLVCDFYLIRTLISLWMLDGSPLRQEDIFALFAMFERWRVSENAAAIRQQIQSLCAAEPLLSAFSLLT
>NZ_CP021844.1|WP_033815265.1|4036718_4037147_+|flagellar-protein-FlgN
MSIRLQQVKALLQGIRDDNKNYDGLRALLEQQRLCMIRRASDELLAVNETIMQHYERLNSTSLQRRSLLQLLGVSVNRAGLEQVFGWLPAAQNNAARHWWQRLEQKAGSCKAYNDKNGELLIRQYEFIQSFLGSEADFLYQE
>NZ_CP021844.1|WP_033815266.1|4036427_4036706_+|flagellar-biosynthesis-anti-sigma-factor-FlgM
MKITPTMPGNRPTATTAGSSQPRKSTATTTTTLSADDITQAGLQSAQQTLNDQQESDIDSNKVAQIQAMLASGSPQVDTEQLASDMLSFFQN
>NZ_CP021844.1|WP_033815267.1|4035609_4036347_+|flagellar-basal-body-P-ring-formation-protein-FlgA
MSFQFCRRKFYFLLALAIPGYAAVHPVQHSAREQVNAQVLNAASQQIESLAQQRQWHDYRYIFKVYIPSQIATAAPCTKTPGVTLTSPAEIALNRMNFTVSCPQSWQMNVAVRPDVLVPVVMAKSVVARDTPLTANDVELKPYNVSAQRRDVLMELDDAIGLSSKHALQPGRPLTKEELVSPVLVERDQPVMIVYQNAGITASMPGVALKNGRKGEMVKVRNASSQRVISAMVAESGVVTTVSAE
>NZ_CP021844.1|WP_123008323.1|4035192_4035528_-|flagellar-basal-body-rod-protein-FlgB
MGISFQQALGVHPQAVKLRLERTELLTANLANVDTPNFKAKDIDFAREMQRANNAAVDVQYRVPMQPSEDGNTVALNSEQARFSQNSMDYQSSLTFLNLQISGIREAIEGK
>NZ_CP021844.1|WP_033815268.1|4034758_4035190_-|flagellar-basal-body-rod-protein-FlgC
MSFTDIYQISGSAMTAQSIRLNTVASNLANAEAPAGSEAQAYKARSPVFAAVYHNSLLAGTHRHAIDGASVQVQDVLQTGGAVKRYEPHSPLADANGDVWYPDVNVVEQMADMMSASRDFETNVDVLNNVKSMQQSLLKLGEA
>NZ_CP021844.1|WP_033815269.1|4034045_4034759_-|flagellar-hook-capping-protein
MNTLALNAQSPQPTATAENNTVAASDTQSSSDSSPVDTFLTLFVAEIQNQDPTDPTDATEYIDQLSSMAQVAMMEEMSVQANTNAVLMSNIQVMALGNLVGDDIMVQTTALQVSDQTINGRATLDDACTTADLHFTDAAGDDYTVSLIPEGSSSVGPGQVDFSVNPADYGIPPGDYDVSVVTNTGEEEVPIEVSGEVEDVRIPLDGSSPVLNVAGVGEVPFTMISQFGVPDADSDVA
>NZ_CP021844.1|WP_033815270.1|4032699_4033902_-|flagellar-basal-body-protein-FlaE
MSYEIAATGLNAVNEQLDGISNNIANAGTVGYKSMTTQFSAMYAGSQAMGVSVAGTAQSISRGGSLVSTGNALDLAINDDGFFVMCDSAGNISYTRAGSFETDKDGYIVNASGDYLQGYPVDDTGTLQTGTVTDIQIKTGNIPAQASSNLTFTANFNASDDAIDRTTVPFDATNSSSYTDSYTTTVYDSLGNEHSVCQYFTKTSDNTWEVQYTFDGQQQTGVPATTLTFDPNTGKLTSPTTPQTIEFQTDAAAPIDLTVDYTTCTQYGSDFSVTTNAANGYASATQNGVQVDDDGKVYATYSNGERMLQGQVVLATFPNENGLEAVSGTAWVQTGESGTPLIGVPGSGTCGTLSSGVLESSNVDITSELVNLMTAQRNYQANTKVIATSTQLDDALFQAM
>NZ_CP021844.1|WP_033815271.1|4031962_4032700_-|flagellar-basal-body-rod-protein-FlgF
MDRLIYTALSGASQTLYEQQISANNLANVNTNGFRADMAMATNDKVKGGGFDTRYMAQEGASGVNDSTGVAEKTERPLDVAIQGAGYIAVQDKNGNEVYTRNGNIQQDDQGQLTIDGNLVLGDNGPIILPPNAIASFGSDGTLSVTPDDGDVTATMDIDRLKLVDIPVANLAKNPEGMLVTGDGVPAQRDENIKVSGGFLEGSNVSAVSEMMSSIAMNRQFEAQIKMMKTAEDISDAGNRLLRGS
>NZ_CP021844.1|WP_088172317.1|4030998_4031784_-|flagellar-basal-body-rod-protein-FlgG
MNAALWISKTGLSAQDAEMSAIANNIANVNTTGFKRDRVMFQDLFYQTQEAPGAMLDQNNIMPTGLQFGSGVRIVGTQKTFTEGNVETTDNAMNVAIMGQGFLQVQKANGDIAYTRDGNLQVNADGVLTNSQGLPLQPEIDVPAGATNVAFGEDGTVTAILPGDSDATELGQLTLVNFANPAGLSAEGDNLYLETAASGQPTEGVPGEDGLGTLQDNALEGSNVDIVNEMVAMITVQRAYEMNAKMASAADDMLQYISQTL
>NZ_CP021844.1|WP_123008325.1|4038464_4040909_+|glycosyltransferase
MPTPTIIKTLATHREKPFVSVVTPTWNRGAFLPYLLYMYRYQDYPADRRELVILDDSPQSHQHIIDRLTNGTPEAFNIRYIYHPEKLPLGKKRNMLNELARGEYIFCMDDDDYYPADKISYTIAMMQKHRALISGSDQIPIWYSHINRIFQSRSFGPHNILNGTFCYHRNYLKKHCYDDDCNLGEEKSFTDNFSVNPLQLPGERTILCISHSHNTFDKDFILGASTPVNAELSDIVRDPLLRNAYLSLHNATHHQAINHQAIDQVVIVNLDKRPDRLQQIREELALLHIPPEKITRLAACEDENGQRGRRQSHLQALRLAQQHGWQNYLLLEDDAVILKQEKHIQVLNTLLASLAKIPWQVMILGGEISQGTMLKSLPGLVHARDCRKVCAYLVNSRYYPQLAQQMSNDEHSLEDDWQPLLRTDKWLACYPSLCYQRPGFSDIEKKETDNISHYFNKLPVATKPSALPVADTIGFFMETSFHYALYRPIITALQEQGQSCTLVINDRVFKPFLDEMLETLKSIDNPLLKGMRLSEMQAHGQRVKCLVSPYHTPALNGLAAVNIRAMYGLAKETWNHADWNRFYQRILCYSHYSQQALAHFGSAKVVGNPRFDAWHNGTFNRSLPENIQPDYRKPTVLYAPTFGALSSLPHWAEKLGRLSGDVNLICKLHHGTCSRPDEAASLALARRHLKQRTDSARHTLALLAKADYVLTDNSGFIFDAIHVDKRVILLDFPGMTELLDGEKSYSTPESADQRIHEILPVAHDMAELRYLLSEAFDWGALQAKLAEIRHHYCDAFMDGKAGERAALVIVEALG
>NZ_CP021844.1|WP_085008556.1|4041309_4042386_+|Fic-family-protein
MKWNPEIPYNDLPGLPPDLECIETRSVLKACISARAAIAELKTAGELLPDQGLLINILPMLEAKDSSRIENIVTTSDRLFQYADREEGADPATKEALRYRTALNDGFTHLEAWPLCTNTAIAICTKLRAVQTDIRKTPGTVLRDQDNNTVYTPPVGEDTIRNLLANWERFIHGDDDLDPLVKMAIAHYQFECIHPFPDGNGRTGRILNILYLIQSELLSLPILYLSRYILENRAAYYTYLRQVTEKGDWESWILFMLAAVENTSRWTTTKIKVVRQLITETTEYVRENLPKIYSHELVQTLFAQPYCRIENLVERNIAKRQTASSYLKQLTEAGVLEEMSVGREKLYLNTRLLRELNQ
>NZ_CP021844.1|WP_085008558.1|4042379_4042784_-|adenylyltransferase/cytidyltransferase-family-protein
MKTVITFGTFDVFHVGHLRLLQRARTLGERLLVGVSSDTLNIAKKGRAPVYHQDDRMAIIAGLACVDGVFLEESLEQKAEYLRGYSADILVMGDDWAGKFDSFAYICEVVYFPRTPSVSTTGIIEVIRGKSATY
>NZ_CP021844.1|WP_088172313.1|4042786_4043221_-|flagellar-export-protein-FliJ
MRQIIDTLAQLQRLRDKSVKDKTVELAKQKQICAGYDNNIKALGYLVEKTSAGAGASVESLKNVSGYKGTLRKVIAWQEQEKTLANIKATRMQKNLTAAACEEKVVALTLDDKRREQQESATAKAQKAVDDIAVQCWLRHKLAE
>NZ_CP021844.1|WP_088172312.1|4043223_4044561_-|flagellar-protein-export-ATPase-FliI
MSDFSAFDNALRSLESIPLARVAGRLVRLNGILLESVGCPLMTGQLCRIESANHTLIDAQAVGFNRDITYLMPFKQPVGLMAGARVFPEEKAHDILIGESWLGRVVNGLGEPLDGKGRLNGNDLLPPLPPSVNPLTRRSVDEPLDVGVKAINGLLTIGKGQRVGLMAGSGVGKSVLLGMITRQTKADIVVVGLIGERGREVKEFIDHSLGADGLAKSIVVVAPADESPLMRLKATELCHSIAAWFRDRGHHVLLLVDSLTRYAMAQREIALSLGEPPATKGYPPSAFGMIPKLVESAGNSESAGSMTAIYTVLAEGDDQQDPIVDCARAVLDGHIVLTRKLAEAGHYPAIDIGQSISRCMNQVTSLEHQQSARVLKQNYAAYMEIKPLIPLGGYVAGADASVDKAVKMFPAIERFLRQEMREPASLELVQSRLQILFPGVKKAEQ
>NZ_CP021844.1|WP_000151519.1|4044553_4045264_-|flagellar-assembly-protein-H
MTIETLRGRYRLHRFPPRQRAVTGEPLTASISAADYQRQLMDGFQEGLQKGFAQGMTEGQEQGFSEGHQQGFAEGRRQGYTEGSLAGQQEGRKQFVEAAQPLEAITGKVNDFLAHIERKQREDLLQLVEKVTRQVIRCELALQPTQLLALVEEALAAFPAMPETLQVMLSTEEFNRLRDAVPEKVSEWGLTPSPDLPPGECRVITDKSELDIGCEHRLEQCMTALKETLTPESQGE
>NZ_CP021844.1|WP_001293120.1|4045267_4046278_-|flagellar-motor-switch-protein-FliG
MSELTINKSNSYLEQAAILLLCLGEEAAATVMQKLSREEVVRLSENMARLSGVKTSMARKVINNFFDEFREQSGINGASRSMLQGILNKALGTEIASSVINGIYGDEIRSRMARLQWVEPRQLAMLISEEHLQLQAVFLAFLTPEISAAVLSYLNESVQNEILYRVAKLNDVNRDVVDELDRLIERGLSVLSEHGSKVKGIKQAADIVNRFQGNQQVILDQMRERDEDVLEQLQDEMYDFFILSRQNEEVRRRLLDEVPMEDWAVALKGTEALLRRSIYAVMPKRQVQQLEAITARLGPVPVSRIEQIRREIMGIARELEEAGEIQLQLFAEQTAE
>NZ_CP021844.1|WP_088172311.1|4046255_4047911_-|flagellar-M-ring-protein-FliF
MNAQIKKLTQAFPAFRLRLADNKRWALMAGVGLAVAATAIIVSVLWNGNRGYVSLYGRQENLPVSQIVTVLDGEKLTYRIDPQSGQILVPEDELSKTRMTLAAKGVQAILPSGYELMDKDEVLGSSQFVQNVRYKRSLEGELAQSIMSLDAVESARVHLALNEESSFVVSDVPQNSASVVVRLHYGAKLNMDQVNAIVHLVSGSIPGLHASKVSVVDQAGNLLTDGIGAGEAVSAATRKRDQILKDIQDKTRASVANVLDSLVGSGNYRVSVMPDLDLSTIEETQEHYGDAPKINREESVLDSDTNQVAMGVPGSLSNRPPVAPNQITNGATPADENRSPEALSKHSESKRDYSYDRSVQHIQHPGFAVKRLNVAVVLNQNAPALKNWKPEQTTQLTALLNNAAGIDVQRGDNLTLSLLNFVPQAVPVEPIIPLWKDGSVLAWVRLIGCGLLALLLLFFVVRPLMKRLTAVRAPVITPEPEAVSEPWIATPEEERKNVDLPSLPGDDSLPSQSSGLEVKLEFLQKLAMSDTDRVAEVLRQWITSNERIDNK
>NZ_CP021844.1|WP_000029084.1|4047915_4048257_-|flagellar-hook-basal-body-complex-protein-FliE
MSITTINSTMQAQIMQDVQRMQANAQAPVLPAMTFSSTDPDVSFNRIMQGALGHVDQFQQVAEQQQTAIDLGKSDDLAGAMIASQQASLSFSALVQVRNKIATGFNDLMSMSI
>NZ_CP021844.1|WP_088172310.1|4048271_4049258_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MSELIATAASSINAFTLAKRVAAFNVPVLIQGETGAGKECVAKYIHTVAFGENENAPYIGVNCAAIPENMLEATLFGYDKGAFTGAIASVPGKMELANNGTLLLDEIGDMPLALQAKILRVLQEQQVERLGSNRQIKLNFRLIACTNKNLEQEVAAGRFREDLYYRLAVIPITMPPLRERLNDIIPLAESFIKKYSTVLVKNITLSESTRRALLNYRWPGNVRQLENAIQRGMILNRDGVIYPDALGLPETTIADHSELQWPVQPAVHIAETSDLGQHGRSAQYQYIADLMRKYQGNRSKIADLLGITPRALRYRLASMRKQGIEVFS

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Crispr_ID: NZ_CP021844_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_10

4055962-4056074

Orphan

Consensus_repeat	Method
GTTTGTAGGCATGATAAGACGCGCCAGCGTCGCATCAGGCATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_10

>merge|NZ_CP021844|10|4055962-4056074|CRISPRCasFinder
GTTTGTAGGCATGATAAGACGCGCCAGCGTCGCATCAGGCATCCGCGCACAATTGCCGGATGCGGCACAAGTTTGTAGGCATGATAAGACGCGCTAGCGTCGCATCAGGCATC

>NZ_CP021844|10|10|4055962-4056074|CRISPRCasFinder
GTTTGTAGGCATGATAAGACGCGCCAGCGTCGCATCAGGCATC	CGCGCACAATTGCCGGATGCGGCACAA
GTTTGTAGGCATGATAAGACGCGCTAGCGTCGCATCAGGCATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_000922509.1\|4049645_4050497_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376445
NZ_CP021844.1\|WP_000333380.1\|4059123_4059891_-\|class-II-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|372525
NZ_CP021844.1\|WP_021576986.1\|4060914_4063359_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236528
NZ_CP021844.1\|WP_001225679.1\|4058412_4059153_+\|murein-L,D-transpeptidase	unknown	unknown	gnl\|CDD\|225577
NZ_CP021844.1\|WP_000284050.1\|4060096_4060675_-\|D-sedoheptulose-7-phosphate-isomerase	unknown	unknown	gnl\|CDD\|179012
NZ_CP021844.1\|WP_033815253.1\|4053781_4055875_+\|flagellar-biosynthesis-protein-FlhA	unknown	unknown	gnl\|CDD\|224217
NZ_CP021844.1\|WP_001260503.1\|4051886_4052669_+\|flagellar-biosynthetic-protein-FliR	unknown	unknown	gnl\|CDD\|224598
NZ_CP021844.1\|WP_000006266.1\|4056083_4056581_-\|REP-associated-tyrosine-transposase-RayT	unknown	unknown	gnl\|CDD\|224854
NZ_CP021844.1\|WP_088172311.1\|4046255_4047911_-\|flagellar-M-ring-protein-FliF	unknown	unknown	gnl\|CDD\|235957
NZ_CP021844.1\|WP_021576987.1\|4057715_4057976_+\|type-II-toxin-antitoxin-system-antitoxin-DinJ	unknown	unknown	gnl\|CDD\|225619
NZ_CP021844.1\|WP_021576985.1\|4064028_4064799_+\|2-oxoglutaramate-amidase	unknown	unknown	gnl\|CDD\|182461
NZ_CP021844.1\|WP_088172310.1\|4048271_4049258_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP021844.1\|WP_088172309.1\|4050489_4050861_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131533
NZ_CP021844.1\|WP_000532698.1\|4063401_4063875_-\|C-lysozyme-inhibitor	unknown	unknown	gnl\|CDD\|182187
NZ_CP021844.1\|WP_000958542.1\|4051612_4051885_+\|flagellar-type-III-secretion-system-protein-FliQ	unknown	unknown	gnl\|CDD\|224898
NZ_CP021844.1\|WP_000615977.1\|4057978_4058257_+\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin-YafQ	unknown	unknown	gnl\|CDD\|225583
NZ_CP021844.1\|WP_088172308.1\|4052658_4053798_+\|flagellar-type-III-secretion-system-protein-FlhB	unknown	unknown	gnl\|CDD\|235569
NZ_CP021844.1\|WP_000056850.1\|4056756_4057506_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|223862
NZ_CP021844.1\|WP_001752076.1\|4050857_4051610_+\|flagellar-type-III-secretion-system-pore-protein-FliP	unknown	unknown	gnl\|CDD\|235566
NZ_CP021844.1\|WP_000029084.1\|4047915_4048257_-\|flagellar-hook-basal-body-complex-protein-FliE	unknown	unknown	gnl\|CDD\|376721

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_000922509.1\|4049645_4050497_+\|hypothetical-protein	gnl\|CDD\|376445	pfam01052, FliMN_C, Type III flagellar switch regulator (C-ring) FliN C-term. This family includes the C-terminal region of flagellar motor switch proteins FliN and FliM. It is associated with family FliM, pfam02154 and family FliN_N pfam16973.	0.000185945
NZ_CP021844.1\|WP_000333380.1\|4059123_4059891_-\|class-II-glutamine-amidotransferase	gnl\|CDD\|372525	pfam13230, GATase_4, Glutamine amidotransferases class-II. This family captures members that are not found in pfam00310.	8.29603e-146
NZ_CP021844.1\|WP_021576986.1\|4060914_4063359_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|236528	PRK09463, fadE, acyl-CoA dehydrogenase; Reviewed.	0
NZ_CP021844.1\|WP_001225679.1\|4058412_4059153_+\|murein-L,D-transpeptidase	gnl\|CDD\|225577	COG3034, COG3034, Uncharacterized protein conserved in bacteria [Function unknown].	1.07529e-116
NZ_CP021844.1\|WP_000284050.1\|4060096_4060675_-\|D-sedoheptulose-7-phosphate-isomerase	gnl\|CDD\|179012	PRK00414, gmhA, D-sedoheptulose 7-phosphate isomerase.	1.61173e-142
NZ_CP021844.1\|WP_033815253.1\|4053781_4055875_+\|flagellar-biosynthesis-protein-FlhA	gnl\|CDD\|224217	COG1298, FlhA, Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP021844.1\|WP_001260503.1\|4051886_4052669_+\|flagellar-biosynthetic-protein-FliR	gnl\|CDD\|224598	COG1684, FliR, Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion].	1.47975e-50
NZ_CP021844.1\|WP_000006266.1\|4056083_4056581_-\|REP-associated-tyrosine-transposase-RayT	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.81915e-41
NZ_CP021844.1\|WP_088172311.1\|4046255_4047911_-\|flagellar-M-ring-protein-FliF	gnl\|CDD\|235957	PRK07193, fliF, flagellar MS-ring protein; Reviewed.	0
NZ_CP021844.1\|WP_021576987.1\|4057715_4057976_+\|type-II-toxin-antitoxin-system-antitoxin-DinJ	gnl\|CDD\|225619	COG3077, RelB, DNA-damage-inducible protein J [DNA replication, recombination, and repair].	1.70694e-29
NZ_CP021844.1\|WP_021576985.1\|4064028_4064799_+\|2-oxoglutaramate-amidase	gnl\|CDD\|182461	PRK10438, PRK10438, C-N hydrolase family amidase; Provisional.	0
NZ_CP021844.1\|WP_088172310.1\|4048271_4049258_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.09583e-122
NZ_CP021844.1\|WP_088172309.1\|4050489_4050861_+\|hypothetical-protein	gnl\|CDD\|131533	TIGR02480, Flagellar_motor_switch_protein_FliN, flagellar motor switch protein FliN. Proteins that consist largely of the domain described by this model for this protein family can be designated flagellar motor switch protein FliN. Longer proteins in which this region is a C-terminal domain typically are designated FliY. More distantly related sequences, outside the scope of this family, are associated with type III secretion and include the surface presentation of antigens protein SpaO required or invasion of host cells by Salmonella enterica. [Cellular processes, Chemotaxis and motility].	3.88968e-21
NZ_CP021844.1\|WP_000532698.1\|4063401_4063875_-\|C-lysozyme-inhibitor	gnl\|CDD\|182187	PRK09993, PRK09993, C-lysozyme inhibitor; Provisional.	9.39999e-93
NZ_CP021844.1\|WP_000958542.1\|4051612_4051885_+\|flagellar-type-III-secretion-system-protein-FliQ	gnl\|CDD\|224898	COG1987, FliQ, Flagellar biosynthesis pathway, component FliQ [Cell motility and secretion / Intracellular trafficking and secretion].	1.3006e-18
NZ_CP021844.1\|WP_000615977.1\|4057978_4058257_+\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin-YafQ	gnl\|CDD\|225583	COG3041, COG3041, Uncharacterized protein conserved in bacteria [Function unknown].	1.98004e-41
NZ_CP021844.1\|WP_088172308.1\|4052658_4053798_+\|flagellar-type-III-secretion-system-protein-FlhB	gnl\|CDD\|235569	PRK05702, flhB, flagellar type III secretion system protein FlhB.	1.44116e-157
NZ_CP021844.1\|WP_000056850.1\|4056756_4057506_-\|C40-family-peptidase	gnl\|CDD\|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	4.42583e-42
NZ_CP021844.1\|WP_001752076.1\|4050857_4051610_+\|flagellar-type-III-secretion-system-pore-protein-FliP	gnl\|CDD\|235566	PRK05699, fliP, flagellar biosynthesis protein FliP; Reviewed.	8.84431e-108
NZ_CP021844.1\|WP_000029084.1\|4047915_4048257_-\|flagellar-hook-basal-body-complex-protein-FliE	gnl\|CDD\|376721	pfam02049, FliE, Flagellar hook-basal body complex protein FliE.	1.37988e-15

>NZ_CP021844.1|WP_033815253.1|4053781_4055875_+|flagellar-biosynthesis-protein-FlhA
MAKTTKSFLALLRGGNLGVPLVILCILAMVILPLPPALLDILFTFNIVLAVMVLLVAVSAKRPLEFSLFPTILLITTLMRLTLNVASTRVVLLHGHLGAGAAGKVIESFGQVVIGGNFVVGFVVFIILMIINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVCIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRHQLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLSSMAPRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSTVTKDHILLAADVRLALRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYNEVPDELELKIMGALS
>NZ_CP021844.1|WP_088172308.1|4052658_4053798_+|flagellar-type-III-secretion-system-protein-FlhB
MADSSSEEKTEKPSAQKLRKAREEGQLPRSKDMGLAASLFAAFVVISSSFPWYADFVRESFISVHQYAQEINKPEVIGQFLRHHLLILGKFILTLLPMPAAALLSSLVPGGWLFLPKKILPDFSKISPLKGIGRLFSSEHLAETGKMTVKSVVVLVMLWISLRNNFTAFLGLQALPFKLAMNDGLSLYASVMRNFVILFIFFALLDVPLAKALFTKGLKMTKQELKEEYKNQEGKPEVKARVRRLQRQLAMGQIRKVVPKANVVITNPTHYAVALQYDQSRAAAPFVVAKGTDEIALYIRQVAAENQVEVVEFPRLARSVYYTTQVNQQIPFQLYRAIAHVLTYVLQMKHWREGAQPRPALNRHISIPKEVLKLDGENN
>NZ_CP021844.1|WP_001260503.1|4051886_4052669_+|flagellar-biosynthetic-protein-FliR
MRTSDVTQLMDLALGLWFPFVRIMAFLRYVPVLDNSALTVRVRIILSLALAIIITPLIPHPIPHDLLSLNSLILTVEQILWGMLFGLMFQFLFLALQLAGQILSFNMGMSMAVMNDPSSGASTTVLAELINVYAILLFFAMDGHLLLVSVLYKGFTYWPIGNALHPQTLRTIALAFSWVLASASLLALPTTFIMLIVQGCFGLLNRIAPPLNLFSLGFPINMLAGLVCFATLLYNLPDHYLHLANFVLQQLDALKGHYGG
>NZ_CP021844.1|WP_000958542.1|4051612_4051885_+|flagellar-type-III-secretion-system-protein-FliQ
MLTVDVAADIVASGIKVVILLVSVLVVPSLLVGLLVSVFQAVTQINEQTLSFLPRLIVTLVVLGVCGKWMIIQLHDLCIHLFTQAALLVH
>NZ_CP021844.1|WP_001752076.1|4050857_4051610_+|flagellar-type-III-secretion-system-pore-protein-FliP
MKRRTQLTLGLGLLALAPLALAQGGDIALLNVVTHGNTQEYSVKIQVLILMTLVGLLPTMVLMMTCFTRFIIVLSLLRQALGLQQTPPNRILIGIALSLTMLVMRPIWLNIYDHAVVPFENDQITLTDALSTAATPLKRFMLAQTDKKAMAQIMTIGGAKGNAADQDLTIVVPAYVLSELKTAFQIGFMIYIPFLVIDLIVASVLMAMGMMMLSPLIVSLPFKLMLFVLIDGWSLTIGTLTTSIRGLGLG
>NZ_CP021844.1|WP_088172309.1|4050489_4050861_+|hypothetical-protein
MSKQEDILAGDFNLTDEAVPTVKSPDAETLVTRLEDRFSDSMTLLKRIPVTLTLEVSSVEIMLADLLNIDDDTVIELDKLAGEPLDIKVNNILLGKAEVVVVNEKYGLRVLEFNTRDINDLAP
>NZ_CP021844.1|WP_000922509.1|4049645_4050497_+|hypothetical-protein
MLKYSKTPGIFKLEGNRLGRPYHRLPTLFTGNFDVIDSHLGSYFLKKHRSNITLKKIGCEMDIINKNAELMVSQVGHLAFDIDRSLLLMLLGNFYGLESSLEEAKAHNGLPTKTETRLKNRLALDICTLIFNLQTSGIALKLKLDSSTVITHWAYQLTFTLAGDEESSFRILLDDAHTDFILNLIRHSEHSKPQQVAKSVNKPALIKEIIRSLPLTLNVKIAELSLNVADLTQIKAGDILPISLGETFPVAIGQSELFSALIVEDKDKLFLSELAGKNENSHE
>NZ_CP021844.1|WP_088172310.1|4048271_4049258_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MSELIATAASSINAFTLAKRVAAFNVPVLIQGETGAGKECVAKYIHTVAFGENENAPYIGVNCAAIPENMLEATLFGYDKGAFTGAIASVPGKMELANNGTLLLDEIGDMPLALQAKILRVLQEQQVERLGSNRQIKLNFRLIACTNKNLEQEVAAGRFREDLYYRLAVIPITMPPLRERLNDIIPLAESFIKKYSTVLVKNITLSESTRRALLNYRWPGNVRQLENAIQRGMILNRDGVIYPDALGLPETTIADHSELQWPVQPAVHIAETSDLGQHGRSAQYQYIADLMRKYQGNRSKIADLLGITPRALRYRLASMRKQGIEVFS
>NZ_CP021844.1|WP_000029084.1|4047915_4048257_-|flagellar-hook-basal-body-complex-protein-FliE
MSITTINSTMQAQIMQDVQRMQANAQAPVLPAMTFSSTDPDVSFNRIMQGALGHVDQFQQVAEQQQTAIDLGKSDDLAGAMIASQQASLSFSALVQVRNKIATGFNDLMSMSI
>NZ_CP021844.1|WP_088172311.1|4046255_4047911_-|flagellar-M-ring-protein-FliF
MNAQIKKLTQAFPAFRLRLADNKRWALMAGVGLAVAATAIIVSVLWNGNRGYVSLYGRQENLPVSQIVTVLDGEKLTYRIDPQSGQILVPEDELSKTRMTLAAKGVQAILPSGYELMDKDEVLGSSQFVQNVRYKRSLEGELAQSIMSLDAVESARVHLALNEESSFVVSDVPQNSASVVVRLHYGAKLNMDQVNAIVHLVSGSIPGLHASKVSVVDQAGNLLTDGIGAGEAVSAATRKRDQILKDIQDKTRASVANVLDSLVGSGNYRVSVMPDLDLSTIEETQEHYGDAPKINREESVLDSDTNQVAMGVPGSLSNRPPVAPNQITNGATPADENRSPEALSKHSESKRDYSYDRSVQHIQHPGFAVKRLNVAVVLNQNAPALKNWKPEQTTQLTALLNNAAGIDVQRGDNLTLSLLNFVPQAVPVEPIIPLWKDGSVLAWVRLIGCGLLALLLLFFVVRPLMKRLTAVRAPVITPEPEAVSEPWIATPEEERKNVDLPSLPGDDSLPSQSSGLEVKLEFLQKLAMSDTDRVAEVLRQWITSNERIDNK
>NZ_CP021844.1|WP_000006266.1|4056083_4056581_-|REP-associated-tyrosine-transposase-RayT
MSEYRRYYLKGGSWFFTVNLRNRRSQLLTTQYQTLRNAIIKVKRARPFEINAWVVLPEHMHCIWTLPESDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHAIRNTKDYRHHVDYIYINPVKHGWVKQVCDWPFSTFHRDVARGLYPIDWAGDITDLSAGERIIL
>NZ_CP021844.1|WP_000056850.1|4056756_4057506_-|C40-family-peptidase
MSLPSIPSFVLSGLLLICLPFSSFASATTSHISFSYAARQRMQNRARLLKQYQTHLKKQASYIVEGNAESRRALRQHNREQIKQHPEWFPAPLKASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVFYAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRTGETIRVSRLAEPFWQDHFLGARRILTEETIL
>NZ_CP021844.1|WP_021576987.1|4057715_4057976_+|type-II-toxin-antitoxin-system-antitoxin-DinJ
MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNKLTIQSIKNSEAGVGVHKAKDADDLFDKLGI
>NZ_CP021844.1|WP_000615977.1|4057978_4058257_+|type-II-toxin-antitoxin-system-mRNA-interferase-toxin-YafQ
MIQRDIEYSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNILPLPAVYKDHPLQGSWKGYRDAHVEPDWLLIYKLTDKLLRFERTGTHAALFG
>NZ_CP021844.1|WP_001225679.1|4058412_4059153_+|murein-L,D-transpeptidase
MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPVYIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQLKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTGALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVNGRYVVSKPLSHEVVQPQLASNYTLPEAK
>NZ_CP021844.1|WP_000333380.1|4059123_4059891_-|class-II-glutamine-amidotransferase
MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGKGCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRNWTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIASLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTTPNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV
>NZ_CP021844.1|WP_000284050.1|4060096_4060675_-|D-sedoheptulose-7-phosphate-isomerase
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
>NZ_CP021844.1|WP_021576986.1|4060914_4063359_+|acyl-CoA-dehydrogenase
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLKEHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQRICKDLGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELATKPVKLPEKVRKVEAA
>NZ_CP021844.1|WP_000532698.1|4063401_4063875_-|C-lysozyme-inhibitor
MGRISSGGMMFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK
>NZ_CP021844.1|WP_021576985.1|4064028_4064799_+|2-oxoglutaramate-amidase
MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMFTSGFAMEAAASSLAQNDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTVHFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLALYVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIATADAHQATRIDAELSMMALREYREKFPAWRDADEFRLR

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Crispr_ID: NZ_CP021844_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_11

4268965-4269099

Orphan

Consensus_repeat	Method
GGCCTACACGCTGCAATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_11

>merge|NZ_CP021844|11|4268965-4269099|CRISPRCasFinder
GGCCTACACGCTGCAATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCATTCAGCGCCTGATGCGACGCTGACGCGTCTTATCTGGCCTACACGCTGCGATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA

>NZ_CP021844|11|11|4268965-4269099|CRISPRCasFinder
GGCCTACACGCTGCAATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA	TTCAGCGCCTGATGCGACGCTGACGCGTCTTATCT
GGCCTACACGCTGCGATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_001117011.1\|4272397_4275304_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP021844.1\|WP_001065381.1\|4283203_4284025_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP021844.1\|WP_021556399.1\|4278509_4280879_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP021844.1\|WP_021576943.1\|4269112_4269808_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP021844.1\|WP_021576945.1\|4260268_4261252_+\|thiamine-ABC-transporter-substrate-binding-subunit	unknown	unknown	gnl\|CDD\|236883
NZ_CP021844.1\|WP_001148407.1\|4263633_4264398_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP021844.1\|WP_001300811.1\|4264483_4265362_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP021844.1\|WP_001399882.1\|4262821_4263520_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	unknown	unknown	gnl\|CDD\|182716
NZ_CP021844.1\|WP_000241272.1\|4282217_4283207_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP021844.1\|WP_000800457.1\|4280931_4282218_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP021844.1\|WP_001248768.1\|4257220_4257352_-\|glucose-uptake-inhibitor-SgrT	unknown	unknown	gnl\|CDD\|374203
NZ_CP021844.1\|WP_000525176.1\|4275315_4275975_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP021844.1\|WP_001200573.1\|4277439_4278255_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP021844.1\|WP_021576944.1\|4261227_4262838_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	unknown	unknown	gnl\|CDD\|181853
NZ_CP021844.1\|WP_021576946.1\|4259327_4259897_-\|T3SS-effector-EspY2	unknown	unknown	unknown
NZ_CP021844.1\|WP_000951873.1\|4265699_4267400_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP021844.1\|WP_021576942.1\|4269882_4272234_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP021844.1\|WP_000151726.1\|4267410_4268913_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP021844.1\|WP_021576941.1\|4276392_4277145_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021844.1\|WP_021576948.1\|4257440_4259099_+\|HTH-type-transcriptional-regulator-SgrR	unknown	unknown	gnl\|CDD\|184188

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_001117011.1\|4272397_4275304_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP021844.1\|WP_001065381.1\|4283203_4284025_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.76119e-148
NZ_CP021844.1\|WP_021556399.1\|4278509_4280879_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP021844.1\|WP_021576943.1\|4269112_4269808_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	1.54195e-178
NZ_CP021844.1\|WP_021576945.1\|4260268_4261252_+\|thiamine-ABC-transporter-substrate-binding-subunit	gnl\|CDD\|236883	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional.	0
NZ_CP021844.1\|WP_001148407.1\|4263633_4264398_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.79494e-49
NZ_CP021844.1\|WP_001300811.1\|4264483_4265362_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP021844.1\|WP_001399882.1\|4262821_4263520_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	gnl\|CDD\|182716	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ.	1.95591e-164
NZ_CP021844.1\|WP_000241272.1\|4282217_4283207_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP021844.1\|WP_000800457.1\|4280931_4282218_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP021844.1\|WP_001248768.1\|4257220_4257352_-\|glucose-uptake-inhibitor-SgrT	gnl\|CDD\|374203	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT.	0.00111324
NZ_CP021844.1\|WP_000525176.1\|4275315_4275975_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	1.37214e-159
NZ_CP021844.1\|WP_001200573.1\|4277439_4278255_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.09407e-169
NZ_CP021844.1\|WP_021576944.1\|4261227_4262838_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	gnl\|CDD\|181853	PRK09433, thiP, thiamine transporter membrane protein; Reviewed.	0
NZ_CP021844.1\|WP_000151726.1\|4267410_4268913_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP021844.1\|WP_000951873.1\|4265699_4267400_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP021844.1\|WP_021576942.1\|4269882_4272234_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP021844.1\|WP_021576948.1\|4257440_4259099_+\|HTH-type-transcriptional-regulator-SgrR	gnl\|CDD\|184188	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR.	0

>NZ_CP021844.1|WP_000151726.1|4267410_4268913_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
>NZ_CP021844.1|WP_000951873.1|4265699_4267400_+|ribulokinase
MAIAIGLDFGSDSVRALAVDCTTGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
>NZ_CP021844.1|WP_001300811.1|4264483_4265362_-|arabinose-operon-transcriptional-regulator-AraC
MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>NZ_CP021844.1|WP_001148407.1|4263633_4264398_-|DedA-family-protein
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLVRHPLMPVYIDILRKVVGV
>NZ_CP021844.1|WP_001399882.1|4262821_4263520_+|thiamine-ABC-transporter-ATP-binding-protein-ThiQ
MLKLTDITWLYQHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTDELLSGKASASALLGITG
>NZ_CP021844.1|WP_021576944.1|4261227_4262838_+|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWSAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVTALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNSTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFTVIEKIPGRNVKTD
>NZ_CP021844.1|WP_021576945.1|4260268_4261252_+|thiamine-ABC-transporter-substrate-binding-subunit
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDIFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDHYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
>NZ_CP021844.1|WP_021576946.1|4259327_4259897_-|T3SS-effector-EspY2
MKVRNPEQISIPASNTTKDPGLTNSQIIRMANLVKKTENMNIFEELWETLRNLFRSDKHSQTAARQILKDAFYFQNSDDYSKYFTGAVDGKVRDQLTHWLIKFNELKEYAKDPENMAAKASLSPEGTLCVSFFIGDEAIFTLELQLKKSTRTGGIDLSNAYFNGVVICGIDCLEVDLSNAETNNSRWYD
>NZ_CP021844.1|WP_021576948.1|4257440_4259099_+|HTH-type-transcriptional-regulator-SgrR
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAGLEHLTLTFYQDHIEHRVIARIMQQILASHQVTMEIKEISYDQWHKGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPLDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>NZ_CP021844.1|WP_001248768.1|4257220_4257352_-|glucose-uptake-inhibitor-SgrT
MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY
>NZ_CP021844.1|WP_021576943.1|4269112_4269808_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSIMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLNKHYLRKHGAKAYYGQ
>NZ_CP021844.1|WP_021576942.1|4269882_4272234_+|DNA-polymerase-II
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGAIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQARGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIGRALVQHVNVWWAETLQKQQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>NZ_CP021844.1|WP_001117011.1|4272397_4275304_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
>NZ_CP021844.1|WP_000525176.1|4275315_4275975_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
>NZ_CP021844.1|WP_021576941.1|4276392_4277145_-|hypothetical-protein
MKVSVPGMPATLLNMSNNDIYKMVSGDKIDVKMNIFQRLWETLRHLFWSDKQTEAYKLLFNFVNKKAGNINASKYFTGAVNENEKEKFINSLELFNELKTCAKNPDEMVAKGSMSWVAQTFGDIELSVTFFIENKEICTQTLQLHKGPGNLGVDLGEAYLPGVDMRDCYLGLKTMKGHNKLLYLEPGWNANLDGATLDGSILDGATVDGATHLYDEVIIINKITPKKIATEEIATKQSTAEEIIANAIIE
>NZ_CP021844.1|WP_001200573.1|4277439_4278255_-|co-chaperone-DjlA
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
>NZ_CP021844.1|WP_021556399.1|4278509_4280879_+|LPS-assembly-protein-LptD
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSNPQNNKLADSVNRVMPQFKVDGKMVFERDMNLLAPGFTQTLEPRVQYLYVPYRDQSDIYNYDSALLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSSSSIEYRRDEDRLVQLNYRYASPEYIQATLPRDSRDKRWNAPQYKDGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
>NZ_CP021844.1|WP_000800457.1|4280931_4282218_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
>NZ_CP021844.1|WP_000241272.1|4282217_4283207_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRTYSPNSPAQPQTAGTLTLLPVALRESVTAGQLAVENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
>NZ_CP021844.1|WP_001065381.1|4283203_4284025_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES

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Crispr_ID: NZ_CP021844_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021844_12

4497615-4497764

Orphan

Consensus_repeat	Method
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021844_12

>merge|NZ_CP021844|12|4497615-4497764|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCATGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

>NZ_CP021844|12|12|4497615-4497764|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCA
TGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021844.1\|WP_000786399.1\|4497931_4498375_+\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP021844.1\|WP_001128336.1\|4489492_4490812_+\|gnt-II-system-L-idonate-transporter	unknown	unknown	gnl\|CDD\|129873
NZ_CP021844.1\|WP_001059398.1\|4502674_4503178_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP021844.1\|WP_001295681.1\|4493617_4494700_-\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP021844.1\|WP_088172281.1\|4491954_4493457_+\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP021844.1\|WP_001197411.1\|4487608_4488640_+\|L-idonate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|182130
NZ_CP021844.1\|WP_088172280.1\|4498374_4501230_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP021844.1\|WP_000397144.1\|4496066_4497578_+\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP021844.1\|WP_000012908.1\|4503801_4504815_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP021844.1\|WP_088172279.1\|4504867_4506658_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021844.1\|WP_000998695.1\|4488663_4489428_+\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|181225
NZ_CP021844.1\|WP_000500711.1\|4508041_4508755_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP021844.1\|WP_053274056.1\|4501285_4502482_-\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP021844.1\|WP_001300770.1\|4485805_4486825_+\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP021844.1\|WP_001297569.1\|4490878_4491877_+\|DNA-binding-transcriptional-regulator-IdnR	unknown	unknown	gnl\|CDD\|380489
NZ_CP021844.1\|WP_001308227.1\|4506780_4507233_-\|DUF386-domain-containing-protein	unknown	unknown	gnl\|CDD\|225345
NZ_CP021844.1\|WP_072686178.1\|4494699_4495800_-\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP021844.1\|WP_000002953.1\|4503223_4503640_-\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP021844.1\|WP_000896738.1\|4486828_4487392_-\|gluconokinase	unknown	unknown	gnl\|CDD\|182097
NZ_CP021844.1\|WP_088172278.1\|4507377_4507971_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP021844.1\|WP_000786399.1\|4497931_4498375_+\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NZ_CP021844.1\|WP_001128336.1\|4489492_4490812_+\|gnt-II-system-L-idonate-transporter	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP021844.1\|WP_001059398.1\|4502674_4503178_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.01499e-18
NZ_CP021844.1\|WP_001295681.1\|4493617_4494700_-\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP021844.1\|WP_088172281.1\|4491954_4493457_+\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP021844.1\|WP_001197411.1\|4487608_4488640_+\|L-idonate-5-dehydrogenase	gnl\|CDD\|182130	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional.	0
NZ_CP021844.1\|WP_088172280.1\|4498374_4501230_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP021844.1\|WP_000397144.1\|4496066_4497578_+\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP021844.1\|WP_000012908.1\|4503801_4504815_+\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP021844.1\|WP_000998695.1\|4488663_4489428_+\|gluconate-5-dehydrogenase	gnl\|CDD\|181225	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional.	0
NZ_CP021844.1\|WP_000500711.1\|4508041_4508755_+\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	7.26747e-150
NZ_CP021844.1\|WP_053274056.1\|4501285_4502482_-\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	6.60196e-151
NZ_CP021844.1\|WP_001300770.1\|4485805_4486825_+\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	4.70369e-169
NZ_CP021844.1\|WP_001297569.1\|4490878_4491877_+\|DNA-binding-transcriptional-regulator-IdnR	gnl\|CDD\|380489	cd01575, PBP1_GntR, ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. This group represents the ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of GntR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding, which in turn changes the DNA binding affinity of the repressor.	2.95382e-109
NZ_CP021844.1\|WP_001308227.1\|4506780_4507233_-\|DUF386-domain-containing-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.17692e-69
NZ_CP021844.1\|WP_072686178.1\|4494699_4495800_-\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP021844.1\|WP_000002953.1\|4503223_4503640_-\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
NZ_CP021844.1\|WP_000896738.1\|4486828_4487392_-\|gluconokinase	gnl\|CDD\|182097	PRK09825, idnK, gluconokinase.	1.3617e-126
NZ_CP021844.1\|WP_088172278.1\|4507377_4507971_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.54954e-10

>NZ_CP021844.1|WP_000397144.1|4496066_4497578_+|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP021844.1|WP_072686178.1|4494699_4495800_-|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWIVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP021844.1|WP_001295681.1|4493617_4494700_-|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP021844.1|WP_088172281.1|4491954_4493457_+|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLTRLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDDVDRESAYEMLQKGFQASNEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRKR
>NZ_CP021844.1|WP_001297569.1|4490878_4491877_+|DNA-binding-transcriptional-regulator-IdnR
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRTAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL
>NZ_CP021844.1|WP_001128336.1|4489492_4490812_+|gnt-II-system-L-idonate-transporter
MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGQYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
>NZ_CP021844.1|WP_000998695.1|4488663_4489428_+|gluconate-5-dehydrogenase
MNDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV
>NZ_CP021844.1|WP_001197411.1|4487608_4488640_+|L-idonate-5-dehydrogenase
MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF
>NZ_CP021844.1|WP_000896738.1|4486828_4487392_-|gluconokinase
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGSASDQRCE
>NZ_CP021844.1|WP_001300770.1|4485805_4486825_+|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF
>NZ_CP021844.1|WP_000786399.1|4497931_4498375_+|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP021844.1|WP_088172280.1|4498374_4501230_+|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEELIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP021844.1|WP_053274056.1|4501285_4502482_-|DUF898-domain-containing-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCRRYLYANMEVNGQRFSYGITGGNVFFSCLVFVFFYFAILMTVSADMPLVGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSLKGFWWVTFFLPILMAIGMGTVFFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIMPSLPFL
>NZ_CP021844.1|WP_001059398.1|4502674_4503178_+|N-acetyltransferase
MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLREL
>NZ_CP021844.1|WP_000002953.1|4503223_4503640_-|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP021844.1|WP_000012908.1|4503801_4504815_+|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSKLNN
>NZ_CP021844.1|WP_088172279.1|4504867_4506658_-|hypothetical-protein
MSKISDLNYSQHITLADNFKQKNEALDTWYVGMNDFARIVGGQNSRSNILSPRAFLEFLAKIFTLGYVDFSKRSNEAGRNMMAHIESSSYSKDTDGNEKMKFYMNNPEGERADLSKVKIEITLASASTKGIREGHTVIIFKQSDGSTNRYEGKSFERKDDSSLHLITNKVLACYQREANKEIARLLNNHQKLNNLQKLNNLQKLNNLQKLNNIQGLNNIQELNNSQKLNNSQELNNPKELNDSQELNNSQDLNNSQVSCKGSVDSTITDLLEKSLNNALLAIRNEHLLLMPHVCSESISYLLGENGILEEIDKLYELNDHGIDNYKEGNNEINDIMINLSHILIESLDDAKVNLTPVIDSMLETFLKFPYINDVRILEWCFNKSMQYSDDAKKIKHACSVINHINLRSDQSKIAETLFFNLDKEPYNNSPELQELIWNKLVVYVNDFNLSNREKIYLIQRLFSNVESIFNKVPVSILVNDIFMKEFFMKNPEMVNWYFPQLLKSYEDEKIYFDKLGYNFNNKESNEEIMENQPKDVIKEKFNNELKLRFRMMQTILKSEVNILPFIDQQRLNTLNPPGNLRIAIEKFGWNKKTITA
>NZ_CP021844.1|WP_001308227.1|4506780_4507233_-|DUF386-domain-containing-protein
MIIGNIHNLQPWLPQELRQAIEHIKAHVTVETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP021844.1|WP_088172278.1|4507377_4507971_-|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVTEVTDYLGINPPSLYAAFGNKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLAEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETAIYDYIARRHPQSAQCVTDFMSTVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE
>NZ_CP021844.1|WP_000500711.1|4508041_4508755_+|SDR-family-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAERLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHGFMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021844_7	7.1\|3095723\|40\|NZ_CP021844\|CRISPRCasFinder	3095723-3095762	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	1	0.975
NZ_CP021844_6	6.1\|2411643\|38\|NZ_CP021844\|CRISPRCasFinder	2411643-2411680	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	101196-101230	2	0.943
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	165464-165498	3	0.914
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	158418-158444	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	386534-386560	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	397084-397110	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	19-45	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	18-44	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	18382-18408	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	18-44	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	18-44	4	0.852
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	6720-6746	5	0.815
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7468-7494	5	0.815
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	83566-83592	5	0.815
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84292-84318	5	0.815
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	14239-14273	5	0.857
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	56080-56114	5	0.857
NZ_CP021844_10	10.1\|4056005\|27\|NZ_CP021844\|CRISPRCasFinder	4056005-4056031	27	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	283162-283188	6	0.778
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	6804-6838	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208981-209015	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219475-219509	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210309-210343	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191264-191298	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30177-30211	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	170-204	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023209	Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence	88-122	6	0.829
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87137-87171	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	138033-138067	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	43-77	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3372-3406	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208887-208921	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	42-76	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3371-3405	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219381-219415	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	42-76	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3371-3405	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210215-210249	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	42-76	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3371-3405	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191170-191204	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	27246-27280	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	18350-18384	7	0.8
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15018-15052	7	0.8
NZ_CP021844_3	3.3\|1137508\|32\|NZ_CP021844\|PILER-CR,CRISPRCasFinder,CRT	1137508-1137539	32	MH617380	Microviridae sp. isolate ctcc639, complete genome	3153-3184	8	0.75
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	61916-61950	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4114-4148	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229148-229182	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229249-229283	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229350-229384	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229451-229485	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	203852-203886	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204038-204072	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204131-204165	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4113-4147	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239642-239676	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239743-239777	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239844-239878	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239945-239979	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214346-214380	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214532-214566	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214625-214659	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4113-4147	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230554-230588	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230655-230689	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230756-230790	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230857-230891	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205180-205214	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205366-205400	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205459-205493	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4113-4147	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211524-211558	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211625-211659	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211726-211760	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211827-211861	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186135-186169	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186321-186355	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186414-186448	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	14272-14306	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	6744-6778	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7392-7426	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	83590-83624	8	0.771
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84216-84250	8	0.771
NZ_CP021844_2	2.1\|1111422\|32\|NZ_CP021844\|PILER-CR,CRISPRCasFinder,CRT	1111422-1111453	32	NZ_CP020744	Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence	111330-111361	9	0.719
NZ_CP021844_8	8.1\|3235770\|32\|NZ_CP021844\|CRISPRCasFinder	3235770-3235801	32	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9736-9767	9	0.719
NZ_CP021844_8	8.1\|3235770\|32\|NZ_CP021844\|CRISPRCasFinder	3235770-3235801	32	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9737-9768	9	0.719
NZ_CP021844_8	8.1\|3235770\|32\|NZ_CP021844\|CRISPRCasFinder	3235770-3235801	32	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9736-9767	9	0.719
NZ_CP021844_8	8.2\|3235830\|33\|NZ_CP021844\|CRISPRCasFinder	3235830-3235862	33	MN855903	Myoviridae sp. isolate 490, partial genome	4171-4203	9	0.727
NZ_CP021844_8	8.3\|3235778\|32\|NZ_CP021844\|PILER-CR	3235778-3235809	32	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9736-9767	9	0.719
NZ_CP021844_8	8.3\|3235778\|32\|NZ_CP021844\|PILER-CR	3235778-3235809	32	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9737-9768	9	0.719
NZ_CP021844_8	8.3\|3235778\|32\|NZ_CP021844\|PILER-CR	3235778-3235809	32	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9736-9767	9	0.719
NZ_CP021844_8	8.4\|3235838\|33\|NZ_CP021844\|PILER-CR	3235838-3235870	33	MN855903	Myoviridae sp. isolate 490, partial genome	4171-4203	9	0.727
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	386558-386592	9	0.743
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4013-4047	9	0.743
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4012-4046	9	0.743
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4012-4046	9	0.743
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4012-4046	9	0.743
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	13988-14022	9	0.743
NZ_CP021844_11	11.1\|4269015\|35\|NZ_CP021844\|CRISPRCasFinder	4269015-4269049	35	NZ_CP019246	Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence	41415-41449	9	0.743
NZ_CP021844_2	2.1\|1111422\|32\|NZ_CP021844\|PILER-CR,CRISPRCasFinder,CRT	1111422-1111453	32	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	809959-809990	10	0.688

1. spacer 7.1|3095723|40|NZ_CP021844|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 1, identity: 0.975

gcgctgcggatcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
*********.******************************

2. spacer 6.1|2411643|38|NZ_CP021844|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

3. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 2, identity: 0.943

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ttcagcgcctgatgcgacgctggcgcgtcttatca	Protospacer
**********************.***********

4. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 3, identity: 0.914

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tgtaacgcctgatgcgacgctgacgcgtcttatct	Protospacer
* .*.******************************

5. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
ggcgcacaattgccggatgcggcgtga	Protospacer
 **********************...*

6. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
agcgcacaagtgccggatgcggcgtaa	Protospacer
 ******** *************..**

7. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
ggtgcacaattgccggatgcggcgtaa	Protospacer
 *.********************..**

8. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
agcgcacaaatgccggatgcggcgtaa	Protospacer
 ******** *************..**

9. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
agcgcacaaatgccggatgcggcgtaa	Protospacer
 ******** *************..**

10. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
agcgcacaaatgccggatgcggcgtaa	Protospacer
 ******** *************..**

11. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
agcgcacaaatgccggatgcggcgtaa	Protospacer
 ******** *************..**

12. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 4, identity: 0.852

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
agcgcacaaatgccggatgcggcgtaa	Protospacer
 ******** *************..**

13. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 5, identity: 0.815

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
tgcgcacaactgccggatgcggcgtga	Protospacer
.********.*************...*

14. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 5, identity: 0.815

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
ggtgcacaattgccggatgcggcgtga	Protospacer
 *.********************...*

15. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 5, identity: 0.815

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
tgcgcacaactgccggatgcggcgtga	Protospacer
.********.*************...*

16. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 5, identity: 0.815

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
ggtgcacaattgccggatgcggcgtga	Protospacer
 *.********************...*

17. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 5, identity: 0.857

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accagcgcctgatgcgccgctgtcgcgtcttatca	Protospacer
 .************** ***** ***********

18. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 5, identity: 0.857

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ctcaacgcctgatgcgacgctggcgcgtcttagcg	Protospacer
.***.*****************.********* *

19. spacer 10.1|4056005|27|NZ_CP021844|CRISPRCasFinder matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 6, identity: 0.778

cgcgcacaattgccggatgcggcacaa	CRISPR spacer
gatgcataattgccggatgccgcacat	Protospacer
 ..***.************* *****

20. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gtttatgccagatgcgacgctgacgcgtcttatct	Protospacer
 *. ..*** *************************

21. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

22. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

23. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

24. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

25. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*.....****************************

26. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
attgaagcctgatgcgacgctgacgcgtcttatca	Protospacer
 *... ****************************

27. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023209 (Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .*...****************************

28. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
cacgatgcctgatgcgacgctgccgcgtcttatca	Protospacer
. *...**************** ***********

29. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tgcgctgcctgatgcgacgctaatgcgtcttatca	Protospacer
* *. .***************.*.**********

30. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

31. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

32. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

33. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

34. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

35. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

36. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

37. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

38. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

39. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

40. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

41. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

42. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accggtgccagatgcgacgcagacgcgtcttatca	Protospacer
 .*.*.*** ********** *************

43. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

44. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ccaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
.. .*.****************.***********

45. spacer 3.3|1137508|32|NZ_CP021844|PILER-CR,CRISPRCasFinder,CRT matches to MH617380 (Microviridae sp. isolate ctcc639, complete genome) position: , mismatch: 8, identity: 0.75

attacgacttccgcacgcacccaccgtttgta	CRISPR spacer
attacgacatccgcacgcccccacgtggtaca	Protospacer
******** ********* *****    *..*

46. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgccagatgcgacgctggcgcgtcttatct	Protospacer
 . ...*** ************.************

47. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

48. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

49. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

50. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

51. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

52. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

53. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

54. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

55. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

56. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

57. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

58. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

59. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

60. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

61. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

62. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

63. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

64. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

65. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

66. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

67. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

68. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

69. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

70. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

71. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

72. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

73. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

74. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

75. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

76. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

77. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

78. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

79. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tgaattacctgatgcgacgctggcgcatcttatca	Protospacer
*  * ..***************.***.*******

80. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatacgacgctgacgcgtcttatca	Protospacer
 . ...*******.********************

81. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ccggatgcctgatgcgacgctggcgcgtcttatca	Protospacer
.. ...****************.***********

82. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatacgacgctgacgcgtcttatca	Protospacer
 . ...*******.********************

83. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ccggatgcctgatgcgacgctggcgcgtcttatca	Protospacer
.. ...****************.***********

84. spacer 2.1|1111422|32|NZ_CP021844|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020744 (Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gccctataatgagaaataaactaattcctatt	CRISPR spacer
ctactataatgaaaaagaaactaattagtctc	Protospacer
 . *********.*** *********  * *.

85. spacer 8.1|3235770|32|NZ_CP021844|CRISPRCasFinder matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

86. spacer 8.1|3235770|32|NZ_CP021844|CRISPRCasFinder matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

87. spacer 8.1|3235770|32|NZ_CP021844|CRISPRCasFinder matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

88. spacer 8.2|3235830|33|NZ_CP021844|CRISPRCasFinder matches to MN855903 (Myoviridae sp. isolate 490, partial genome) position: , mismatch: 9, identity: 0.727

gttcgctgcaaccgctagccaagacggtaggtt	CRISPR spacer
gttcgctgcaaccgttcgccaagaccacaaagg	Protospacer
**************.* ******** ..*..

89. spacer 8.3|3235778|32|NZ_CP021844|PILER-CR matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

90. spacer 8.3|3235778|32|NZ_CP021844|PILER-CR matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

91. spacer 8.3|3235778|32|NZ_CP021844|PILER-CR matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

92. spacer 8.4|3235838|33|NZ_CP021844|PILER-CR matches to MN855903 (Myoviridae sp. isolate 490, partial genome) position: , mismatch: 9, identity: 0.727

gttcgctgcaaccgctagccaagacggtaggtt	CRISPR spacer
gttcgctgcaaccgttcgccaagaccacaaagg	Protospacer
**************.* ******** ..*..

93. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgatgctaacgcgtcttatca	Protospacer
 .....***********.***.************

94. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

95. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

96. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

97. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

98. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
acggatgcccgatgcgacgctggcgcgtcttatcg	Protospacer
 . ...***.************.***********

99. spacer 11.1|4269015|35|NZ_CP021844|CRISPRCasFinder matches to NZ_CP019246 (Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgtctgatgcgacgctggcgcgtcttatca	Protospacer
 .....*.**************.***********

100. spacer 2.1|1111422|32|NZ_CP021844|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 10, identity: 0.688

gccctataatgagaaataaactaattcctatt	CRISPR spacer
ctaaaaaaatgtaaaataaactaattcctaaa	Protospacer
 .   * **** .*****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1257786 : 1336728

Shigella_phage(42.31%)

head,capsid,tail,tRNA,holin,plate,terminase,portal,integrase,protease

attL 1248891:1248905|attR 1297199:1297213

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1248891:1248905	attL	NA	NA	NA	NA
WP_088172161.1\|1257786_1259028_-\|integrase	integrase	A0A1B5FPC6	Escherichia_phage	9.1e-102	48.6
WP_032211342.1\|1259388_1260075_-	RloB domain-containing protein	NA	NA	NA	NA
WP_044527605.1\|1260074_1261340_-	ATP-binding protein	V9QJ85	Oenococcus_phage	9.5e-06	29.9
WP_054632495.1\|1261530_1262727_-	DUF3596 domain-containing protein	I6PDJ1	Cronobacter_phage	1.8e-147	66.3
WP_001331174.1\|1262687_1262894_-	hypothetical protein	I6PBM8	Cronobacter_phage	6.9e-23	70.3
WP_001331173.1\|1262953_1263169_-	hypothetical protein	K7PLX1	Enterobacteria_phage	1.2e-14	65.1
WP_063118231.1\|1263165_1263528_-	hypothetical protein	A5LH61	Enterobacteria_phage	2.0e-65	97.4
WP_000008235.1\|1263518_1264055_-	5'-deoxynucleotidase	S5MW55	Escherichia_phage	8.2e-100	98.9
WP_000016389.1\|1264599_1265034_+	hypothetical protein	U5P096	Shigella_phage	8.4e-79	100.0
WP_000549626.1\|1265005_1265212_-	hypothetical protein	NA	NA	NA	NA
WP_000450735.1\|1265459_1266086_-	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	5.5e-47	48.8
WP_000205494.1\|1266183_1266384_+	cell division protein	NA	NA	NA	NA
WP_001434539.1\|1266421_1266973_+	hypothetical protein	S5FXP0	Shigella_phage	7.6e-101	98.9
WP_001250269.1\|1267148_1267328_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_088177430.1\|1267317_1268259_+	helix-turn-helix domain-containing protein	S5FM81	Shigella_phage	9.5e-144	99.4
WP_001305611.1\|1268255_1268750_+	PerC family transcriptional regulator	A0A291AWV6	Escherichia_phage	1.5e-87	99.4
WP_001305610.1\|1268749_1269403_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	3.3e-127	99.1
WP_000210154.1\|1269399_1269726_+	LexA family transcriptional regulator	A0A0N7KZF7	Stx2-converting_phage	2.7e-53	99.1
WP_040074681.1\|1269722_1270112_+	RusA family crossover junction endodeoxyribonuclease	A0A291AX14	Escherichia_phage	4.6e-68	98.4
WP_001061438.1\|1270131_1270941_+	KilA-N domain-containing protein	A5LH75	Enterobacteria_phage	8.2e-152	100.0
WP_074613456.1\|1270948_1271938_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	6.2e-194	99.1
WP_024225791.1\|1271956_1272298_+	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	6.0e-56	87.6
WP_137503319.1\|1272324_1273053_-	hypothetical protein	NA	NA	NA	NA
WP_024225789.1\|1273061_1273325_-	hypothetical protein	NA	NA	NA	NA
WP_001120491.1\|1273617_1273944_+\|holin	phage holin, lambda family	S5FM86	Shigella_phage	6.8e-57	99.1
WP_021563578.1\|1273947_1274424_+	glycoside hydrolase family protein	U5P0A9	Shigella_phage	2.9e-88	99.4
WP_012599940.1\|1274407_1274800_+	DUF2570 domain-containing protein	Q8SBD9	Shigella_phage	1.4e-53	86.2
WP_016159276.1\|1275325_1275760_+	hypothetical protein	NA	NA	NA	NA
WP_001135210.1\|1275887_1276238_+	HNH endonuclease	M1FQV2	Enterobacteria_phage	3.1e-63	96.6
WP_000929180.1\|1276363_1276858_+\|terminase	phage terminase small subunit P27 family	Q8SBI1	Shigella_phage	6.6e-88	99.4
WP_089078575.1\|1277091_1278588_+\|terminase	terminase large subunit	U5P0Q5	Shigella_phage	3.1e-290	98.8
WP_015364399.1\|1278735_1279962_+\|portal	phage portal protein	Q8SBI0	Shigella_phage	4.9e-241	99.3
WP_000999805.1\|1279954_1280557_+\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	6.8e-111	100.0
WP_000766100.1\|1280567_1281797_+\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	7.6e-226	99.3
WP_000924829.1\|1281876_1282200_+\|head,tail	phage gp6-like head-tail connector protein	Q8SBH7	Shigella_phage	1.7e-52	99.1
WP_000702395.1\|1282196_1282607_+\|head	phage head closure protein	M1FJ87	Enterobacteria_phage	5.7e-69	93.4
WP_000224835.1\|1282581_1283088_+	hypothetical protein	M1FPE2	Enterobacteria_phage	1.3e-83	92.9
WP_000779296.1\|1283084_1283645_+	hypothetical protein	Q8SBH4	Shigella_phage	6.1e-106	100.0
WP_000497751.1\|1283653_1283824_+	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	9.3e-26	100.0
WP_054625654.1\|1283807_1285304_+\|tail	phage tail protein	M1FN90	Enterobacteria_phage	9.5e-271	98.2
WP_000090998.1\|1285303_1285660_+	hypothetical protein	U5P076	Shigella_phage	5.3e-63	100.0
WP_000661054.1\|1285659_1285929_+\|tail	phage tail assembly protein	M1FPE4	Enterobacteria_phage	3.5e-43	100.0
WP_024244102.1\|1286070_1287903_+\|tail	phage tail tape measure protein	S5FM63	Shigella_phage	9.1e-300	97.4
WP_000679479.1\|1287994_1288525_+	hypothetical protein	NA	NA	NA	NA
WP_063118235.1\|1288586_1289915_+	DNA circularization protein	Q8SBG8	Shigella_phage	1.9e-246	99.1
WP_020219053.1\|1289911_1290991_+\|plate	baseplate protein	U5P0H6	Shigella_phage	3.4e-206	99.4
WP_001259084.1\|1290990_1291539_+\|plate	phage baseplate assembly protein	U5P081	Shigella_phage	5.1e-97	98.9
WP_000424747.1\|1291538_1291964_+	hypothetical protein	U5P0R9	Shigella_phage	2.0e-80	99.3
WP_088172159.1\|1291950_1293009_+\|plate	baseplate J/gp47 family protein	M1FQW3	Enterobacteria_phage	1.8e-199	98.6
WP_000383572.1\|1292999_1293584_+	YmfQ family protein	O22003	Shigella_phage	2.4e-113	99.5
WP_021546515.1\|1294172_1294601_+\|tail	tail fiber assembly protein	U5P083	Shigella_phage	8.1e-26	50.7
WP_063118164.1\|1294572_1295175_-\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	2.7e-99	90.0
WP_063118165.1\|1295174_1295720_-\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	3.4e-53	57.5
WP_000904997.1\|1295749_1296304_+	site-specific DNA recombinase	A0A1S6L009	Salmonella_phage	8.2e-87	87.8
WP_001137529.1\|1296502_1296715_+	hypothetical protein	NA	NA	NA	NA
WP_000054185.1\|1296799_1297144_-	hypothetical protein	NA	NA	NA	NA
WP_021530618.1\|1297195_1298227_-	hypothetical protein	NA	NA	NA	NA
1297199:1297213	attR	NA	NA	NA	NA
WP_000162574.1\|1299013_1299496_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_021577828.1\|1299627_1300104_+	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_001117838.1\|1300093_1300384_+	RnfH family protein	NA	NA	NA	NA
WP_001203437.1\|1300445_1300787_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_021577827.1\|1300935_1302597_-	DNA repair protein RecN	NA	NA	NA	NA
WP_001059169.1\|1302682_1303561_-	NAD(+) kinase	NA	NA	NA	NA
WP_001307957.1\|1303683_1304277_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_010723175.1\|1304331_1305618_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001338897.1\|1305639_1306431_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_000460035.1\|1306597_1307959_+	signal recognition particle protein	NA	NA	NA	NA
WP_000256450.1\|1308095_1308344_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_000043335.1\|1308362_1308911_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000264777.1\|1308941_1309709_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000065253.1\|1309750_1310098_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_000589826.1\|1310174_1310657_-	OmpA family protein	NA	NA	NA	NA
WP_021577824.1\|1311904_1312423_-	YfiR family protein	NA	NA	NA	NA
WP_024248389.1\|1312572_1312938_-	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_001168032.1\|1313147_1314218_+	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	6.9e-90	51.2
WP_000225221.1\|1314228_1315350_+	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_000200120.1\|1315392_1316553_-	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_001386991.1\|1316651_1316699_-	hypothetical protein	NA	NA	NA	NA
WP_000178456.1\|1316802_1317144_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_000197686.1\|1317414_1318152_-	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000079112.1\|1318286_1319267_+	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_021577822.1\|1319263_1319995_+	polyphenol oxidase	NA	NA	NA	NA
WP_001235102.1\|1320124_1322698_+	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000841103.1\|1328472_1329771_+	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	1.3e-45	32.2
WP_001300818.1\|1329767_1330091_-	YfiM family lipoprotein	NA	NA	NA	NA
WP_021577821.1\|1330136_1331492_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_000082981.1\|1331605_1334266_-	protein lysine acetyltransferase	NA	NA	NA	NA
WP_021577820.1\|1334297_1334996_-	DTW domain-containing protein	NA	NA	NA	NA
WP_001098726.1\|1335064_1335484_-	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_000997418.1\|1335690_1336728_+\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA

DBSCAN-SWA_2

1574456 : 1655658

Enterobacteria_phage(47.69%)

head,capsid,tRNA,holin,transposase,lysis,terminase,portal,integrase,protease

attL 1573916:1573931|attR 1624022:1624037

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1573916:1573931	attL	NA	NA	NA	NA
WP_088172478.1\|1574456_1575482_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	2.1e-168	87.8
WP_024235421.1\|1575511_1576477_-	DUF4062 domain-containing protein	NA	NA	NA	NA
WP_023203535.1\|1576923_1577196_-	ogr/Delta-like zinc finger family protein	A0A2I8TV89	Erwinia_phage	6.3e-08	44.9
WP_023203536.1\|1577195_1577957_-\|capsid	phage capsid morphogenesis protein	NA	NA	NA	NA
WP_023203537.1\|1578357_1581030_-	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	2.1e-58	34.4
WP_023203538.1\|1581026_1581410_-	hypothetical protein	NA	NA	NA	NA
WP_023203539.1\|1581406_1581691_-	hypothetical protein	NA	NA	NA	NA
WP_023203540.1\|1581722_1582082_-	hypothetical protein	NA	NA	NA	NA
WP_001118612.1\|1582074_1582251_-	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	4.2e-05	55.6
WP_024235422.1\|1582382_1582562_+	hypothetical protein	A0A2H4JB52	uncultured_Caudovirales_phage	2.2e-09	54.2
WP_023203543.1\|1582613_1582823_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_024235423.1\|1582930_1583905_-	hypothetical protein	A0A1W6JPD1	Morganella_phage	6.6e-07	53.8
WP_088172477.1\|1583979_1585251_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	8.2e-74	38.9
WP_001163428.1\|1585523_1585724_-	response regulator inhibitor TorI	K7P7V0	Enterobacteria_phage	2.4e-33	100.0
WP_088172475.1\|1585781_1585949_-	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	2.9e-27	100.0
WP_088172474.1\|1586136_1586703_-	DUF551 domain-containing protein	Q76H45	Enterobacteria_phage	2.7e-61	61.4
WP_000118152.1\|1586704_1587004_-	hypothetical protein	Q716F3	Shigella_phage	1.5e-58	100.0
WP_001214453.1\|1587000_1587168_-	DUF2737 family protein	Q716F2	Shigella_phage	1.7e-24	100.0
WP_088172473.1\|1587178_1587472_-	DUF2856 family protein	K7P845	Enterobacteria_phage	2.1e-49	97.9
WP_088172472.1\|1587564_1588026_-	single-stranded DNA-binding protein	K7PHK1	Enterobacteria_phage	1.3e-69	98.0
WP_000365291.1\|1588026_1588734_-	recombinase	Q716E7	Shigella_phage	7.6e-138	100.0
WP_001243355.1\|1588988_1589141_-	host cell division inhibitory peptide Kil	A5VWA5	Enterobacteria_phage	4.7e-21	100.0
WP_000638547.1\|1589125_1589257_-\|protease	protease FtsH-inhibitory lysogeny factor CIII	A5VWA4	Enterobacteria_phage	1.4e-16	100.0
WP_078398964.1\|1589281_1590250_-	cell envelope biogenesis protein TolA	G5DA88	Enterobacteria_phage	7.7e-56	100.0
WP_053878063.1\|1590539_1590830_-	hypothetical protein	K7PH98	Enterobacteria_phage	1.6e-33	77.8
WP_000394299.1\|1590869_1591121_-	hypothetical protein	A4KWV4	Enterobacteria_phage	5.6e-43	100.0
WP_000219338.1\|1591129_1591429_-	hypothetical protein	A5VW99	Enterobacteria_phage	9.0e-32	100.0
WP_000856967.1\|1591743_1592394_-	LexA family transcriptional regulator	A5VW98	Enterobacteria_phage	1.1e-122	100.0
WP_000276886.1\|1592474_1592660_+	hypothetical protein	A5VW97	Enterobacteria_phage	1.6e-26	100.0
WP_015966855.1\|1592768_1593047_+	ABC transporter	K7P8A8	Enterobacteria_phage	1.1e-42	100.0
WP_088172471.1\|1593229_1594051_+	replication protein	K7PJZ3	Enterobacterial_phage	3.7e-152	98.9
WP_088172470.1\|1594047_1595421_+	AAA family ATPase	K7P7K2	Enterobacteria_phage	1.2e-243	96.5
WP_088172469.1\|1595502_1595688_+	hypothetical protein	A0A1B1W2E1	Salmonella_phage	2.1e-18	70.5
WP_088172468.1\|1595716_1595965_+	hypothetical protein	NA	NA	NA	NA
WP_088172467.1\|1595976_1596243_+	hypothetical protein	A0A2I6PIG0	Escherichia_phage	7.8e-27	65.7
WP_023145903.1\|1596247_1596502_+	hypothetical protein	A0A2I6PIF4	Escherichia_phage	2.9e-39	96.4
WP_088172466.1\|1596482_1596923_+	recombination protein NinB	A0A2I6PIF6	Escherichia_phage	2.9e-79	98.6
WP_001752315.1\|1596919_1597447_+	phage N-6-adenine-methyltransferase	A0A1I9LJP9	Stx_converting_phage	4.7e-100	99.4
WP_001254220.1\|1597443_1597620_+	NinE family protein	K7PHE6	Enterobacteria_phage	2.7e-28	100.0
WP_125134125.1\|1597622_1597991_+	DUF2591 domain-containing protein	I6R9D1	Salmonella_phage	1.5e-44	72.1
WP_000950943.1\|1597983_1598160_+	protein ninF	A0A220NRM2	Escherichia_phage	2.5e-26	98.3
WP_032198668.1\|1598152_1598875_+	DNA-binding protein	K7PL51	Enterobacteria_phage	1.3e-121	93.3
WP_000002244.1\|1598874_1599165_+	DUF1364 domain-containing protein	A0A192Y6R9	Salmonella_phage	1.0e-51	100.0
WP_001008193.1\|1599161_1599524_+	RusA family crossover junction endodeoxyribonuclease	A5VW85	Enterobacteria_phage	2.7e-62	99.2
WP_088172464.1\|1599520_1599709_+	protein ninH	A5VW84	Enterobacteria_phage	1.6e-26	98.4
WP_088172463.1\|1599705_1600224_+	DUF1133 family protein	A0A192Y911	Salmonella_phage	1.0e-94	98.3
WP_000783734.1\|1600685_1601009_+\|holin	phage holin, lambda family	G5DA93	Enterobacteria_phage	1.3e-52	100.0
WP_088172462.1\|1600992_1601469_+	glycoside hydrolase family protein	G5DA94	Enterobacteria_phage	1.7e-88	99.4
WP_029701281.1\|1601465_1601933_+\|lysis	lysis protein	A0A291AWW3	Escherichia_phage	6.7e-74	95.5
WP_001139680.1\|1601920_1602073_+	hypothetical protein	K7PKL2	Enterobacteria_phage	1.2e-21	100.0
WP_000807788.1\|1602381_1602624_+	DUF2560 family protein	A5VW77	Enterobacteria_phage	1.3e-36	100.0
WP_000091987.1\|1602625_1602805_+	hypothetical protein	A0A088CPS9	Enterobacteria_phage	3.7e-25	100.0
WP_001436504.1\|1602828_1603251_+	hypothetical protein	Q716H4	Shigella_phage	7.2e-75	100.0
WP_088172461.1\|1603247_1604660_+\|terminase	PBSX family phage terminase large subunit	Q716H3	Shigella_phage	9.8e-278	99.8
WP_088172460.1\|1604662_1606789_+\|portal	portal protein	Q9AYZ9	Salmonella_phage	0.0e+00	99.4
WP_088172459.1\|1606802_1607687_+\|capsid	phage capsid protein	Q716H1	Shigella_phage	8.1e-145	99.7
WP_088172458.1\|1607698_1608970_+\|head	head protein	Q9AYZ7	Salmonella_phage	6.9e-230	95.5
WP_000375639.1\|1609012_1609198_+	hypothetical protein	Q716G9	Shigella_phage	4.6e-26	98.4
WP_088172348.1\|1609518_1610731_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	5.1e-166	98.0
WP_088172457.1\|1610976_1612395_+	hypothetical protein	A0A088CQ70	Enterobacteria_phage	1.7e-274	98.9
WP_000785555.1\|1612394_1613243_+	Packaged DNA stabilization protein gp26	Q716G6	Shigella_phage	2.6e-100	92.9
WP_000614033.1\|1613242_1613698_+	DUF2824 family protein	A5VW67	Enterobacteria_phage	6.7e-87	99.3
WP_088172456.1\|1613700_1614393_+	DNA transfer protein	G5DA80	Enterobacteria_phage	6.0e-111	99.1
WP_088172455.1\|1614402_1615809_+	acyltransferase	I6RSG0	Salmonella_phage	8.4e-128	55.8
WP_088172454.1\|1615808_1617653_+	DNA transfer protein	A0A192Y934	Salmonella_phage	2.6e-246	74.1
WP_000749291.1\|1617667_1618153_-	hypothetical protein	NA	NA	NA	NA
WP_000287055.1\|1618223_1618490_-	Arc family DNA-binding protein	A0A088CPT2	Enterobacteria_phage	9.5e-33	90.5
WP_060618121.1\|1618621_1619131_-	HNH endonuclease	A0A291AXK3	Shigella_phage	4.5e-31	44.9
WP_088172453.1\|1621533_1622616_+	acyltransferase	A0A2H4JA46	uncultured_Caudovirales_phage	5.8e-20	26.9
WP_088172452.1\|1622683_1623853_-\|integrase	prophage integrase IntS	Q716F9	Shigella_phage	2.3e-219	98.7
WP_000368131.1\|1624164_1625097_-	transporter	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
1624022:1624037	attR	NA	NA	NA	NA
WP_000776768.1\|1625389_1626145_+	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_088172451.1\|1626326_1627409_-	hypothetical protein	NA	NA	NA	NA
WP_001307921.1\|1627773_1629114_-	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_000030901.1\|1629485_1629770_+	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_021577760.1\|1629950_1631261_+	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_021577759.1\|1631260_1633405_+	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_001195819.1\|1633607_1634093_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_000033336.1\|1634736_1635300_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_001362314.1\|1635381_1638021_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_000182874.1\|1638043_1638793_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_001252728.1\|1638808_1639300_+	fimbrial protein	NA	NA	NA	NA
WP_021577758.1\|1639296_1639782_+	fimbrial protein	NA	NA	NA	NA
WP_021577757.1\|1639778_1640303_+	fimbrial protein	NA	NA	NA	NA
WP_021577756.1\|1640304_1641147_+	DUF2544 domain-containing protein	NA	NA	NA	NA
WP_000730806.1\|1641314_1641866_-	endonuclease SmrB	NA	NA	NA	NA
WP_001309606.1\|1642031_1642964_+	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_001307917.1\|1642998_1644084_+	chorismate synthase	A0A291AU41	Pandoravirus	2.7e-89	47.5
WP_001043835.1\|1644087_1644912_+	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_000447356.1\|1644911_1645721_+	TSUP family transporter	NA	NA	NA	NA
WP_021577755.1\|1645720_1646269_+	elongation factor P hydroxylase	NA	NA	NA	NA
WP_000559764.1\|1646302_1646581_+	YfcL family protein	NA	NA	NA	NA
WP_021577754.1\|1646701_1648708_-\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_000817183.1\|1648866_1650087_+	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_000127774.1\|1650361_1651540_+	arabinose transporter	NA	NA	NA	NA
WP_000615822.1\|1651536_1652532_-	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_021577753.1\|1652630_1653767_+	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	2.6e-23	29.4
WP_001289167.1\|1653832_1654846_+	USG-1 protein	NA	NA	NA	NA
WP_088172450.1\|1654845_1655658_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA

DBSCAN-SWA_3

1875184 : 1884629

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021577703.1\|1875184_1876111_+	glycine betaine ABC transporter ATP binding protein YehX	F2Y1V5	Organic_Lake_phycodnavirus	2.0e-08	26.8
WP_000783120.1\|1876115_1876847_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|1876827_1876935_-	protein YohO	NA	NA	NA	NA
WP_001240399.1\|1876994_1877726_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.8e-111	99.0
WP_001295431.1\|1877947_1879633_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|1879629_1880349_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_021577702.1\|1880395_1880866_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	5.2e-82	99.4
WP_001295429.1\|1880906_1881368_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_021577701.1\|1881492_1883496_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	98.8
WP_001292774.1\|1883492_1884629_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7

DBSCAN-SWA_4

1975532 : 1983055

Enterobacteria_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001116129.1\|1975532_1976927_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	1.1e-18	30.9
WP_053882441.1\|1977084_1978080_+	SDR family oxidoreductase	A0A1V0QG29	Shearwaterpox_virus	4.2e-09	26.3
WP_000183060.1\|1978322_1979216_+	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_033870517.1\|1979587_1980673_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.3e-100	53.9
WP_044863830.1\|1980672_1981572_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	3.3e-29	35.2
WP_033870519.1\|1981629_1982508_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.0e-107	64.5
WP_033870520.1\|1982512_1983055_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.7e-44	57.9

DBSCAN-SWA_5

3366054 : 3410767

Enterobacteria_phage(57.89%)

head,capsid,tail,transposase,lysis,terminase,portal,integrase,protease

attL 3376095:3376110|attR 3419644:3419659

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088172356.1\|3366054_3367386_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.4e-20	37.1
WP_088172355.1\|3367459_3368044_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	9.2e-105	95.4
WP_088172494.1\|3368043_3371445_-	short-chain fatty acid transporter	X2KTY7	Enterobacteria_phage	1.2e-10	34.5
WP_001230352.1\|3371509_3372109_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	1.3e-109	97.5
WP_088172354.1\|3372179_3375677_-	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	97.7
WP_000090891.1\|3375737_3376370_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	2.2e-96	99.5
3376095:3376110	attL	NA	NA	NA	NA
WP_032200652.1\|3376306_3377050_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.0e-148	97.2
WP_001152502.1\|3377055_3377754_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	8.9e-131	97.8
WP_000847373.1\|3377753_3378083_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	2.1e-58	99.1
WP_088172353.1\|3378079_3380659_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	97.3
WP_088172352.1\|3380651_3381086_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	1.5e-64	99.2
WP_000479153.1\|3381067_3381490_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	6.7e-73	100.0
WP_088569077.1\|3381505_3382246_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	6.1e-130	98.0
WP_000683142.1\|3382253_3382649_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	2.9e-70	99.2
WP_042033450.1\|3382645_3383224_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	2.5e-78	98.4
WP_000753006.1\|3383235_3383589_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	4.4e-62	98.3
WP_000158888.1\|3383600_3383996_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.9e-54	92.4
WP_042033446.1\|3384037_3385063_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	4.3e-190	98.5
WP_005113102.1\|3385118_3385451_-\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	1.9e-54	99.1
WP_000123307.1\|3385460_3386780_-	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	6.7e-236	99.5
WP_001349919.1\|3386760_3388362_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	5.9e-311	99.6
WP_000198149.1\|3388358_3388565_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001027268.1\|3388561_3390487_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.7
WP_000453600.1\|3390461_3391007_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.1e-94	98.9
WP_001663509.1\|3391395_3391629_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	2.5e-21	96.3
WP_000079508.1\|3391685_3392096_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	1.3e-52	76.3
WP_001139678.1\|3392447_3392600_-	hypothetical protein	K7PKL2	Enterobacteria_phage	3.1e-20	96.0
WP_001228702.1\|3392628_3392835_-	hypothetical protein	H6WRZ6	Salmonella_phage	5.3e-31	98.5
WP_001135261.1\|3393051_3393549_-	lysozyme	A0A1B5FP97	Escherichia_phage	4.2e-90	97.6
WP_000839582.1\|3393548_3393764_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	1.2e-33	98.6
WP_000592546.1\|3395033_3395993_-	DUF523 and DUF1722 domain-containing protein	NA	NA	NA	NA
WP_000780581.1\|3396185_3396710_+	lipocalin family protein	A0A1W6JNX6	Morganella_phage	1.1e-48	54.1
WP_001204777.1\|3396865_3397243_-	antitermination protein	Q777W5	Enterobacteria_phage	7.3e-55	84.2
WP_000971055.1\|3397328_3397469_-	YlcG family protein	K7PHH3	Enterobacteria_phage	1.1e-08	69.8
WP_001540841.1\|3397465_3397828_-	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	9.5e-60	95.7
WP_000950954.1\|3397847_3398042_-	protein ninF	NA	NA	NA	NA
WP_000386643.1\|3398034_3398376_-	DUF2591 domain-containing protein	Q76H72	Enterobacteria_phage	1.6e-61	96.5
WP_001254223.1\|3398378_3398555_-	NinE family protein	K7PHE6	Enterobacteria_phage	1.4e-27	98.3
WP_088172348.1\|3398838_3400051_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	5.1e-166	98.0
WP_000185503.1\|3400234_3401134_-	replication protein	M1FN81	Enterobacteria_phage	1.7e-174	100.0
WP_032292260.1\|3401168_3401450_-	hypothetical protein	K7PMG0	Enterobacteria_phage	6.3e-43	97.8
WP_000391959.1\|3401566_3401797_-	hypothetical protein	K7PHA1	Enterobacteria_phage	1.1e-37	100.0
WP_032292259.1\|3401905_3402592_+	helix-turn-helix transcriptional regulator	K7PK07	Enterobacteria_phage	4.4e-130	99.6
WP_077760542.1\|3403137_3403593_+	antitermination protein	J3JZZ6	Escherichia_phage	2.3e-63	97.6
WP_000281856.1\|3403593_3404076_-	superinfection exclusion protein B	A4KWR7	Enterobacteria_phage	1.1e-87	100.0
WP_001542700.1\|3404342_3404543_+	restriction inhibitor protein ral	A0A088CQ62	Enterobacteria_phage	1.2e-32	98.5
WP_001542699.1\|3404725_3405094_+	DUF2528 family protein	M1FPD2	Enterobacteria_phage	2.9e-64	97.5
WP_001198860.1\|3405166_3405331_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	A0A0N6WES3	Escherichia_phage	1.4e-26	100.0
WP_000372923.1\|3405299_3405443_+	host cell division inhibitory peptide Kil	A0A0N7C2U2	Escherichia_phage	2.7e-18	97.9
WP_000995439.1\|3405518_3405815_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000100847.1\|3405820_3406606_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_001537863.1\|3406602_3407283_+	YqaJ viral recombinase family protein	A0A0P0ZCQ7	Stx2-converting_phage	4.6e-132	99.1
WP_000682318.1\|3407279_3407462_+	DUF1317 domain-containing protein	A0A0N7CHV0	Escherichia_phage	1.3e-28	98.3
WP_000548531.1\|3407434_3407626_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	7.3e-27	100.0
WP_001386642.1\|3407636_3407918_+	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	5.5e-47	98.9
WP_000763367.1\|3408016_3408238_+	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	2.9e-35	100.0
WP_001348592.1\|3408448_3409051_-	hypothetical protein	NA	NA	NA	NA
WP_000545745.1\|3409293_3409461_+	hypothetical protein	A5VWB7	Enterobacteria_phage	2.9e-27	98.2
WP_001303849.1\|3409500_3409719_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000533642.1\|3409696_3410767_+\|integrase	tyrosine-type recombinase/integrase	Q9MCR4	Enterobacteria_phage	5.1e-202	100.0
3419644:3419659	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3958303 : 3988321

Pseudomonas_phage(14.29%)

integrase,transposase

attL 3979291:3979305|attR 3990162:3990176

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000144688.1\|3958303_3959623_+\|integrase	site-specific integrase	A0A2H4J5F8	uncultured_Caudovirales_phage	1.5e-17	23.4
WP_039025884.1\|3959715_3960564_-	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_000772024.1\|3960660_3960858_-	DUF957 domain-containing protein	NA	NA	NA	NA
WP_039025883.1\|3961362_3961740_-	type IV toxin-antitoxin system toxin CbtA	NA	NA	NA	NA
WP_039025882.1\|3961828_3962197_-	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
WP_088172326.1\|3962246_3962801_-	antitoxin of toxin-antitoxin stability system	A0A2I6PI07	Pseudomonas_phage	5.1e-20	31.8
WP_001298859.1\|3962981_3964523_+\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
WP_001016257.1\|3964537_3965284_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
WP_000692353.1\|3965491_3965713_-	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
WP_001186774.1\|3965775_3966252_-	RadC family protein	NA	NA	NA	NA
WP_001563926.1\|3966267_3966753_-	antirestriction protein	A9J566	Pseudomonas_phage	4.0e-13	31.7
WP_001598214.1\|3966844_3967663_-	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	1.5e-44	37.6
WP_088172325.1\|3968001_3970848_-	autotransporter adhesin Ag43	NA	NA	NA	NA
WP_039025961.1\|3971220_3972093_-	GTPase family protein	NA	NA	NA	NA
WP_039025962.1\|3972356_3973913_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.4e-104	42.7
WP_001682441.1\|3974946_3975738_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
WP_001456218.1\|3975826_3976669_-	alpha/beta fold putative hydrolase EstX	W8EKH7	Mycobacterium_phage	3.0e-08	26.1
WP_072042932.1\|3976869_3977103_-	hypothetical protein	NA	NA	NA	NA
WP_001120888.1\|3977133_3978627_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000027057.1\|3978836_3979697_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
3979291:3979305	attL	NA	NA	NA	NA
WP_001067855.1\|3980119_3980824_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_011058339.1\|3982019_3982106_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691727.1\|3982121_3984041_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
WP_001067858.1\|3986053_3986758_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000845054.1\|3987307_3988321_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	6.1e-72	45.5
3990162:3990176	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP021846

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 78041

Escherichia_phage(52.63%)

transposase,integrase

attL 16193:16252|attR 41450:43238

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001351995.1\|157_799_+	hypothetical protein	A0A077SK30	Escherichia_phage	2.3e-109	95.8
WP_071447930.1\|901_2029_+	RelA/SpoT domain-containing protein	A0A1B0VBT5	Salmonella_phage	2.0e-156	74.4
WP_000747845.1\|2065_2314_-	hypothetical protein	Q71TG0	Escherichia_phage	4.0e-41	98.8
WP_000224043.1\|2310_2751_-	hypothetical protein	A0A077SLF0	Escherichia_phage	1.7e-79	100.0
WP_085947771.1\|2870_4032_+\|transposase	IS3-like element IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.1e-51	40.6
WP_072778934.1\|6975_10491_+	autotransporter outer membrane beta-barrel domain-containing protein	A0A2L1IV18	Escherichia_phage	2.0e-98	36.1
WP_000896262.1\|10860_11061_+	DUF839 domain-containing protein	NA	NA	NA	NA
WP_000222771.1\|11350_11638_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	4.5e-20	50.5
WP_001139206.1\|11634_11886_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_076751473.1\|12498_15357_+	helicase	Q1MVN7	Enterobacteria_phage	0.0e+00	98.4
16193:16252	attL	NA	NA	NA	NA
WP_001067858.1\|18144_18849_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_001067858.1\|18960_19665_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000679427.1\|19900_20248_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001206356.1\|20411_21203_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_001336345.1\|21208_21499_-	DUF1010 domain-containing protein	NA	NA	NA	NA
WP_001083725.1\|21610_22108_-	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
WP_000845048.1\|22255_23269_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001067855.1\|23736_24441_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000133024.1\|24583_25306_-	hypothetical protein	NA	NA	NA	NA
WP_000071636.1\|25302_25788_-	hypothetical protein	NA	NA	NA	NA
WP_001352021.1\|26812_27343_+	hypothetical protein	NA	NA	NA	NA
WP_000543166.1\|29506_29956_+	hypothetical protein	NA	NA	NA	NA
WP_001352025.1\|30500_32009_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	8.1e-44	31.7
WP_001254943.1\|33171_34323_+\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	7.5e-42	35.6
WP_001067855.1\|36284_36989_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001067858.1\|37100_37805_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000058717.1\|38297_39182_+	EamA family transporter	NA	NA	NA	NA
WP_000804064.1\|39213_40413_-	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_072109431.1\|40491_41154_+	tetracycline resistance transcriptional repressor TetR(A)	NA	NA	NA	NA
WP_000844627.1\|41185_41428_-\|transposase	transposase	NA	NA	NA	NA
WP_001138014.1\|41485_44452_-\|transposase	Tn3-like element TnAs1 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	100.0
41450:43238	attR	NA	NA	NA	NA
WP_001067858.1\|44525_45230_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_032187889.1\|45314_45620_-\|transposase	IS3 family transposase	U5P4I9	Shigella_phage	4.9e-25	88.4
WP_088172348.1\|45686_46900_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	5.1e-166	98.0
WP_001352007.1\|47363_47519_+	type I toxin-antitoxin system toxin HokD	A0A1I9LJU7	Stx_converting_phage	4.0e-15	90.2
WP_000509940.1\|48983_49493_-	hypothetical protein	Q1MVJ9	Enterobacteria_phage	6.6e-91	99.4
WP_000035250.1\|49504_50086_-	hypothetical protein	Q71TM4	Escherichia_phage	1.8e-100	96.9
WP_072779020.1\|50121_50937_-	hypothetical protein	A0A1B0V835	Salmonella_phage	1.1e-108	94.5
WP_000459149.1\|50946_52218_-	hypothetical protein	A0A1B0V7E4	Salmonella_phage	3.0e-241	97.9
WP_088177441.1\|52242_53516_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.8e-170	95.7
WP_000067707.1\|53931_55638_-	hypothetical protein	Q71TM1	Escherichia_phage	0.0e+00	99.8
WP_000038866.1\|55863_56865_-	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	1.7e-178	100.0
WP_001285362.1\|56881_58078_-	ParA family protein	A0A077SL49	Escherichia_phage	1.6e-225	100.0
WP_001154682.1\|58246_59056_-	GIY-YIG nuclease family protein	A0A077SK46	Escherichia_phage	1.6e-155	97.8
WP_001113742.1\|59348_60233_-	RepB family plasmid replication initiator protein	A0A077SLP3	Escherichia_phage	2.1e-161	100.0
WP_001281115.1\|60568_60961_-	hypothetical protein	A0A077SLJ1	Escherichia_phage	7.6e-71	97.7
WP_000336812.1\|60970_61111_-	hypothetical protein	Q71TL6	Escherichia_phage	6.3e-20	100.0
WP_000007763.1\|61136_61559_-	hypothetical protein	Q71TL5	Escherichia_phage	9.4e-59	97.1
WP_000890209.1\|61598_62387_-	hypothetical protein	A0A1B0V830	Salmonella_phage	7.8e-115	95.8
WP_085948178.1\|66170_67383_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_076751476.1\|68184_71658_+	cellulose biosynthesis protein BcsC	NA	NA	NA	NA
WP_000578338.1\|72665_73400_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000124023.1\|75053_78041_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.7e-295	53.5

DBSCAN-SWA_2

82168 : 91516

Escherichia_phage(75.0%)

integrase

attL 88802:88815|attR 90363:90376

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069067570.1\|82168_83431_+	hypothetical protein	Q1MVG4	Enterobacteria_phage	3.9e-233	99.0
WP_001190711.1\|84808_85030_+	type II toxin-antitoxin system Phd/YefM family antitoxin	A0A222YXU1	Escherichia_phage	3.3e-31	98.6
WP_001216039.1\|85029_85410_+	type II toxin-antitoxin system death-on-curing family toxin	Q71T66	Escherichia_phage	9.7e-63	99.2
WP_000113018.1\|85414_85594_+	hypothetical protein	Q71TH5	Escherichia_phage	1.2e-23	98.3
WP_069067567.1\|85621_86665_+	DUF968 domain-containing protein	A0A077SLM1	Escherichia_phage	1.5e-203	98.6
WP_001351993.1\|86967_87279_+	phage antirepressor Ant	A0A077SLR9	Escherichia_phage	2.9e-49	98.0
WP_000611661.1\|87311_88163_-	hypothetical protein	A0A077SLM8	Escherichia_phage	1.0e-157	99.3
WP_000874156.1\|88273_88483_-	hypothetical protein	A0A077SK26	Escherichia_phage	1.8e-31	100.0
88802:88815	attL	NA	NA	NA	NA
WP_000542338.1\|89087_89309_+	hypothetical protein	Q5QBN7	Enterobacteria_phage	4.2e-34	97.3
WP_000067537.1\|89316_90348_+\|integrase	site-specific integrase	A0A077SLE7	Escherichia_phage	1.9e-193	99.1
WP_001224232.1\|90398_90710_+	hypothetical protein	A0A077SK03	Escherichia_phage	8.8e-46	97.1
90363:90376	attR	NA	NA	NA	NA
WP_000848370.1\|90955_91516_+	Ref family protein	Q5QBN4	Enterobacteria_phage	2.8e-95	95.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP021847

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7822 : 18566

Enterobacteria_phage(33.33%)

integrase,transposase

attL 11335:11394|attR 14935:15591

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000027057.1\|7822_8683_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|10418_10976_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_020219413.1\|11139_11280_+	hypothetical protein	Q1MVP5	Enterobacteria_phage	1.3e-09	93.8
11335:11394	attL	NA	NA	NA	NA
WP_001067858.1\|11397_12102_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_015057121.1\|11992_12952_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.7e-47	40.5
WP_032491824.1\|13100_13892_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA22	NA	NA	NA	NA
WP_000939727.1\|14023_14845_+	lincosamide nucleotidyltransferase Lnu(F)	NA	NA	NA	NA
WP_001067858.1\|14997_15702_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
14935:15591	attR	NA	NA	NA	NA
WP_011264039.1\|15774_16014_+	macrolide transporter	A0A2K5B2B5	Erysipelothrix_phage	9.5e-08	46.2
WP_000612791.1\|16159_17023_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	2.5e-05	31.0
WP_001354008.1\|17060_17306_+	hypothetical protein	NA	NA	NA	NA
WP_000034420.1\|17774_18566_+	sulfonamide-resistant dihydropteroate synthase Sul3	A0A0B5J4J5	Pandoravirus	1.2e-14	26.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage