CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021867	Streptococcus agalactiae strain SG-M25 chromosome, complete genome	2 crisprs	DinG,cas9,cas1,cas2,csn2,csm6,DEDDh,cas3	1	11	10	3

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021867_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021867_1

768575-768791

Orphan

Consensus_repeat	Method
TCTGGAATGGGATCAAAGC	CRT

3 spacers

The CRISPR arrays of NZ_CP021867_1

>merge|NZ_CP021867|1|768575-768791|CRT
CCTGGAATGGGATCAAAGGCACCATGACAAACTTACTTAATAGTATCAAATCTGTCGTTAGTAATGTCTGGAATGGCATCAAATCCACGATTAGTTCCATTCTATCGAGTATTGGTTCAACGGTATCTTCTATCTGGAATGGGATGAAAGCAACCATCTCAGGTGTCCTAAGTGGTATTTCAAACACAGTGACCTCTGTCTGGAATGGGGTCAAAGC

>NZ_CP021867|1|1|768575-768791|CRT
CCTGGAATGGGATCAAAGG	CACCATGACAAACTTACTTAATAGTATCAAATCTGTCGTTAGTAATG
TCTGGAATGGCATCAAATC	CACGATTAGTTCCATTCTATCGAGTATTGGTTCAACGGTATCTTCTA
TCTGGAATGGGATGAAAGC	AACCATCTCAGGTGTCCTAAGTGGTATTTCAAACACAGTGACCTCTG
TCTGGAATGGGGTCAAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021867.1\|WP_000123549.1\|776737_776845_+\|putative-holin-like-toxin	unknown	unknown	gnl\|CDD\|319017
NZ_CP021867.1\|WP_000796402.1\|772921_774778_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|310464
NZ_CP021867.1\|WP_000149738.1\|759970_760297_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021867.1\|WP_001225240.1\|761646_762345_+\|Clp-protease-ClpP	unknown	unknown	gnl\|CDD\|132927
NZ_CP021867.1\|WP_000290966.1\|777152_778394_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NZ_CP021867.1\|WP_000589858.1\|769268_769994_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227066
NZ_CP021867.1\|WP_001142755.1\|782333_782555_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021867.1\|WP_000966166.1\|769993_772909_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|227263
NZ_CP021867.1\|WP_000672531.1\|780817_782116_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021867.1\|WP_000818566.1\|764857_765427_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|273713
NZ_CP021867.1\|WP_001249615.1\|765438_765858_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021867.1\|WP_001209973.1\|764528_764855_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021867.1\|WP_172396919.1\|778296_779643_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|238206
NZ_CP021867.1\|WP_000705390.1\|763820_764159_+\|head-tail-adaptor-protein	unknown	unknown	gnl\|CDD\|377521
NZ_CP021867.1\|WP_000661350.1\|774795_775194_+\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|377457
NZ_CP021867.1\|WP_000132373.1\|779725_780796_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021867.1\|WP_000523693.1\|760364_761654_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|377413
NZ_CP021867.1\|WP_000987322.1\|763563_763821_+\|phage-gp6-like-head-tail-connector-protein	unknown	unknown	gnl\|CDD\|153446
NZ_CP021867.1\|WP_000040493.1\|762358_763567_+\|phage-major-capsid-protein	unknown	unknown	gnl\|CDD\|273690
NZ_CP021867.1\|WP_000161243.1\|764151_764520_+\|HK97-gp10-family-phage-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP021867.1\|WP_000796402.1\|772921_774778_+\|hypothetical-protein	gnl\|CDD\|310464	pfam05895, DUF859, Siphovirus protein of unknown function (DUF859). This family consists of several uncharacterized proteins from the Siphoviruses as well as one bacterial sequence. Some of the members of this family are described as putative minor structural proteins.	0
NZ_CP021867.1\|WP_000123549.1\|776737_776845_+\|putative-holin-like-toxin	gnl\|CDD\|319017	pfam16935, Hol_Tox, Putative Holin-like Toxin (Hol-Tox). Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.	0.000621774
NZ_CP021867.1\|WP_001225240.1\|761646_762345_+\|Clp-protease-ClpP	gnl\|CDD\|132927	cd07016, S14_ClpP_1, Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease. Clp protease (caseinolytic protease; ClpP; Peptidase S14) is a highly conserved serine protease present throughout in bacteria and eukaryota, but seems to be absent in archaea, mollicutes and some fungi. This subfamily only contains bacterial sequences. Clp proteases are involved in a number of cellular processes such as degradation of misfolded proteins, regulation of short-lived proteins and housekeeping removal of dysfunctional proteins. They are also implicated in the control of cell growth, targeting DNA-binding protein from starved cells. ClpP has also been linked to the tight regulation of virulence genes in the pathogens Listeria monocytogenes and Salmonella typhimurium. This enzyme belong to the family of ATP-dependent proteases; the functional Clp protease is comprised of two components: a proteolytic component and one of several regulatory ATPase components, both of which are required for effective levels of protease activity in the presence of ATP, although the proteolytic subunit alone does possess some catalytic activity. Active site consists of the triad Ser, His and Asp; some members have lost all of these active site residues and are therefore inactive, while others may have one or two large insertions. ClpP seems to prefer hydrophobic or non-polar residues at P1 or P1' positions in its substrate. The protease exists as a tetradecamer made up of two heptameric rings stacked back-to-back such that the catalytic triad of each subunit is located at the interface between three monomers, thus making oligomerization essential for function.	8.97496e-75
NZ_CP021867.1\|WP_000290966.1\|777152_778394_+\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	2.0642e-37
NZ_CP021867.1\|WP_000589858.1\|769268_769994_+\|hypothetical-protein	gnl\|CDD\|227066	COG4722, COG4722, Phage-related protein [Function unknown].	5.34034e-05
NZ_CP021867.1\|WP_000966166.1\|769993_772909_+\|phage-tail-protein	gnl\|CDD\|227263	COG4926, PblB, Phage-related protein [Function unknown].	2.14498e-33
NZ_CP021867.1\|WP_000818566.1\|764857_765427_+\|phage-tail-protein	gnl\|CDD\|273713	TIGR01603, Uncharacterized_phage_related_protein, phage major tail protein, phi13 family. This model describes a set of proteins that share low levels of sequence similarity but similar lengths and similar patterns of charged, hydrophobic, and Gly/Pro residues. All members (except one attributed to mouse embryo cDNA) belong to phage of Gram-positive bacteria. Several are identified as phage major tail proteins. Some members of this family have additional C-terminal regions of about 100 residues not included in this model. [Mobile and extrachromosomal element functions, Prophage functions].	2.24087e-23
NZ_CP021867.1\|WP_172396919.1\|778296_779643_+\|recombinase-family-protein	gnl\|CDD\|238206	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.	1.74951e-45
NZ_CP021867.1\|WP_000705390.1\|763820_764159_+\|head-tail-adaptor-protein	gnl\|CDD\|377521	pfam05521, Phage_H_T_join, Phage head-tail joining protein.	4.12549e-13
NZ_CP021867.1\|WP_000661350.1\|774795_775194_+\|phage-holin-family-protein	gnl\|CDD\|377457	pfam05105, Phage_holin_4_1, Bacteriophage holin family. Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination. This family also includes TcdE/UtxA involved in toxin secretion in Clostridium difficile. The 1.E.10 family is represented by Bacillus subtilis phi29 holin; 1.E.16 represents the Cph1 holin; and the 1.E.19 family is represented by the Clostridium difficile TcdE holin. Toxigenic strains of C. difficile produce two large toxins (TcdA and TcdB) encoded within a pathogenicity locus. tcdE, encoded between tcdA and tcdB, encodes a 166 aa protein which causes death to E. coli when expressed, and the structure of TcdE resembles holins. TcdE acts on the bacterial membrane. Since TcdA and TcdB lack signal peptides, they may be released via TcdE either prior to or subsequent to cell lysis.	1.16717e-38
NZ_CP021867.1\|WP_000523693.1\|760364_761654_+\|phage-portal-protein	gnl\|CDD\|377413	pfam04860, Phage_portal, Phage portal protein. Bacteriophage portal proteins form a dodecamer and is located at a five-fold vertex of the viral capsid. The portal complex forms a channel through which the viral DNA is packaged into the capsid, and exits during infection. The portal protein is though to rotate during DNA packaging. Portal proteins from different phage show little sequence homology, so this family does not represent all portal proteins.	3.28187e-127
NZ_CP021867.1\|WP_000987322.1\|763563_763821_+\|phage-gp6-like-head-tail-connector-protein	gnl\|CDD\|153446	cd08054, gp6, Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins. The bacteriophage HK97 gp6 protein is critical in the assembly of the connector, a specialized structure that serves as an interface for head and tail attachment, as well as a point at which DNA exits the head during infection by the bacteriophage. It forms a dodecameric ring structure that comprises the middle ring of the connector, located between the portal protein (attached to the head) and the gp7 ring (attached to the tail). It is a component of the mature phage and the absence of HK97 gp6 results in defective head-tail joining and the absence of mature phage particles. Although the crystal structure of HK97 gp6 shows an unexpected 13-mer ring, the biological form present in the mature phage is believed to be a dodecamer.	4.56115e-12
NZ_CP021867.1\|WP_000040493.1\|762358_763567_+\|phage-major-capsid-protein	gnl\|CDD\|273690	TIGR01554, prophage_Lp3_protein_18, phage major capsid protein, HK97 family. This model family represents the major capsid protein component of the heads (capsids) of bacteriophage HK97, phi-105, P27, and related phage. This model represents one of several analogous families lacking detectable sequence similarity. The gene encoding this component is typically located in an operon encoding the small and large terminase subunits, the portal protein and the prohead or maturation protease. [Mobile and extrachromosomal element functions, Prophage functions].	1.46204e-116

>NZ_CP021867.1|WP_001249615.1|765438_765858_+|hypothetical-protein
MRQNITIAGKTYPLATNAYTPIAYKEQFGKDYFQELFNMLSAESIMAQLEQLDEGEELKASQIDLSILSDFDITFFHRLFWVFAKSANPRIKPFEDFFMSMEEFPLQEVGPVLMSMLNQGMTTRKKQITQNQRARKSSR
>NZ_CP021867.1|WP_000818566.1|764857_765427_+|phage-tail-protein
MAEKNKVTFGLQDVHWAEVTNERADGALTYGTVERLRGAAELTLEPTGDKGSYKADNINFYTTESNDGYEGTLKVALLSQEFLTRVLGEKLDATTNTISEIANSEKKNFALMFRFEGDKKETLHVLYYCYASRPTVGSKTKSGSDINEVELTFTASPRPLDKIVRRRTTEETSDEIRENWFKSVFEPTT
>NZ_CP021867.1|WP_001209973.1|764528_764855_+|hypothetical-protein
MRFEELFPVLKKTKLPVAYHHFEEGHSPSPPFMVYLVTDSDNLGADNWAYHKTINLQIELYTTKKDLATEKTVESLLDAHRLHFDKVEIYIANEKLYQTIYSITLLGG
>NZ_CP021867.1|WP_000161243.1|764151_764520_+|HK97-gp10-family-phage-protein
MTKIGLDDLASVIEKELTTYAKETTDTMREVVEEVTDDAVETLKVTSPKRRGKYAKGWTSKATTDTNTALTKTIHNRTPGLTHLLEDGHAKQNGGRVEGRKHISPVEKKAIQSFEDKLRQKL
>NZ_CP021867.1|WP_000705390.1|763820_764159_+|head-tail-adaptor-protein
MKITPLREQLVFQEKRLRQDDIGNEAAIWDDLFMRWCSCRPMALTESDGSATKIVHNKVQFTLRYDKKVLALNSLTTRIYFRDQYYAIESLDGDTVPRRLIYVVATKEEIYD
>NZ_CP021867.1|WP_000987322.1|763563_763821_+|phage-gp6-like-head-tail-connector-protein
MMSLEEVKLYLKVENDEEDFLIEQLMTSSRQLCLDIIRETSTSEVLKTAILYGVAYLYEHREEASHKELKETLYHLLLADRKEVF
>NZ_CP021867.1|WP_000040493.1|762358_763567_+|phage-major-capsid-protein
MSKLLELKEKRNAAWAQAKAFLDTVRSEDGLVSDEDAKRYEEMEAKIELYNKEIARLERQEKIDLELAQPTSQALTTQPTVIVDNQKEDEKKGVASDIYTQTFWTSIRKRHFYDVKDVLRVGEDTEGGHLVPDEYEKKLVQGLQEENFFRSLATVIKTSSGERKIPVVTGHGSASWMDENGLYPETDETFGQVTLDSHKIGTAIRISEELLNDSVFDLESYMTSEFARRIGTEEEKSFLVGDGSKKPTGIFTQADVEGPTTSTKDITFDDMIELYHSLPAPYRKNAVWVLHDTTVKAIRKLKDNNGNYIWQPSTQAGQPDLILNRPYYTSTFAPLPEAGNKAIAFGDFSYYWIADRQGRTFKRLNELYANNGQIGFLASQRVDGKLVLPEAVKVLTVKGKAV
>NZ_CP021867.1|WP_001225240.1|761646_762345_+|Clp-protease-ClpP
MRKFWNFTDQGDVRTLRIEGQIADETWFGDEVTPQLFKNDLSAGTGDITLWINSPGGDVFAAAQIYNMLMDYKGDVHVIIDGLAASAASVIAMAGTTVSMSPVAMMMIHNPWTFAQGEAKDMAKVIEMLGEIKESIINAYEIKTGLSRTKISHLMDSESWFNAKKAVELGFADKVLFEKEETPEQDHQNSYTFSRVTASHDLVVKLQASLQPPKPQKTIPFNQLEKRLNLLK
>NZ_CP021867.1|WP_000523693.1|760364_761654_+|phage-portal-protein
MGLLDSLGRKRARDKPKNSYEGQDFSYLFGRTTSGENVDEFKAMQTTAVYACVRILAEAVASLPIHVYELTSNGKEKKIDHPLYFLLHDEPNPEMSSFIFRETIMSHLLIWGNAYVQIIRDKAGRVISLYPLLPDKMSIHRDGSGKLYYKYQRQTEENPNFKDKGTVLLKQENILHVPGLGFDGLIGYSPVAMVKNAIGMTLATENYGAAFFKNGANPGGVLEHPGILKDPKRVRDSWNAVYNGATNAHKVAVLEEGMKYTQVGIPPEEAQFLQTRKFQINEIARLYRIPPHMVGDLEKSSFSNIEQQSLEFVKYTLDPWVVRLEQAFKRSLFLPEEKKRYLIKFNVDGLLRGDYQSRMNGYAIARQNGWLSTNDIRELEDLNLLSDEEGGNLYLINGNMTKLKDAGGFMKQPTETESAEDPPEEEEDA
>NZ_CP021867.1|WP_000149738.1|759970_760297_+|hypothetical-protein
MTHSILSLEVENELLSSVREVCAEYDLKLEELVKDYLGFLAGLNASAIEQVSALPNENEKAEWLAKYYFDARINQLQFEALKKEVLIGHDQIKESKVTRLEDVRHEFD
>NZ_CP021867.1|WP_000589858.1|769268_769994_+|hypothetical-protein
MIKHNELVLNGKGTSSFPFKVLVEDRPSIQVPRSKTQLLDHRGLSGAIVQTNKHRDAIEKPYRMYLIGASEKEVNEFSAYLMQEGFWLESERLKLTRLWCYRTDSFDIKQDDHDVYVTDVVFICHPTRFFKSVDRQVLSANGVLKTQGSALAFPTITITGQSVSETSFTVGDQVVRIEKFTEPLVMVNHPDRPSFKTLSGKAVKWSGDFITIDASHSTQSVGVILGSGILSLTFETNWGWV
>NZ_CP021867.1|WP_000966166.1|769993_772909_+|phage-tail-protein
MLYLLDGQTKTAKWNGQPLFETVSATVEEELNGTFQLRLTYPITDSGVHEILRADELILCPTPDLGKQLFRIKQAKIQDDMVELECYHISDDVMKRQIKPFSATNTTCQSALMRLVEACPSDLGLFSFDSDVTERHTYVSDENLTLYQALMDGKHSLLGTWEGELVRDNFQLMVKKYRGIDKGVILTSHHNLKTFEDKGDSEKVITRIYATSTFQVEGSDEDTVLSVVVESPLINQYPYVHEARYENNTLQTEEELRQWAMAKFTHEHIDSISRQITVEAYQLDGQEVHLGDTVTLKSQKHKVDVRKKAVGYTFDALEEVYLSVTFDDEVSFTTSGLSGTHSLTSAAKTILNVNQSVTEHRASKERANFNKVFDRQFERLQTEVEDGIAIAKAEGERSGKKAALDYLATDALEARVAALQKATIDELTVSSSAWMTRLVSQQILSEYAKSLEVEADRVVIPGQHTPVFSLDRDGNLSIDTPLLKVRGESLATTADLKTISLTPGPKGEAGEDGVGIQSREQYYLVSAQKTGLTTTSSGWSKTIPSLTSALKYLWNYEKTTFTNGSTTVTTPIVIGVYGDKGVDGKAGKDGKTLYTWRMYADSDKGEGLSAIPTGKRYLGLAVNRESATSSTNPSDYTWSSFFEGTELGGRNYIDDYAMKAATFSSVTSEWKKEVVEDTSSVSGVTVKMTCTKAGTGGFHRNFYDLRNRIGANKTFSVDLKASKAVSLTIGNELGGTKVVQVSPSWQRYSVSWKVGSAQNHSYVFYLKSGTWAVGDVVYLRNVQLEDGNVASAPGPSLNDLIAQIDAKADNGFMKQQLDLLTEKTESLRVDLEARALAKEVADWLKSYKEFEKNNEAVLAQFNQDFIDNTARIAAIEADLKANSLLLNFVNTYLRAGDNGVIIGKKDNSEVIELTPQGMMIRSAGNAVMTVTAGVIKIHHGVFVETLQVGYYRLEAARHNAKHLVCRFIDAK
>NZ_CP021867.1|WP_000796402.1|772921_774778_+|hypothetical-protein
MADYGSNNDRGYTLLLRVEETGTSTADNTSTVRVQLWLKNGYTTFGMYDCRASVSINGQTLSWSGRPDMYTAHSSLHLIDKTITVPHDSNGSKTISFSATFSGSGGWSPGTLNTGSQLLRLSDIPRSSSATVSGNMMGQAVTITIKRASSDFTHNMTWHFGSLSGTIGTGIATSATWMPSISQLATQIPNSASGNGHLTLATIYGGKTIGSMTIPITLNLPASVVPTLGGISVSESHVTAKTILTGTSFAQLVSNPKVTFNQGAGIYGSTTPSTGYRAEVFKFENNQWVQLPNVATSNNGLLGGINWIGRAKVSAYVIDSRGRQSARKEVEITLLEYFKPIFSFSAVRAGSSMNQVTVTRKLKIAPLTISNVQKNKATLTWEVVDLSSGQKVTNAGGAANWTSTTEHTKMDFQAILGGTYDTTKSYTIIGTLADLFYSTTFEFTIGPEKVVYGLSPSGMGIGKAWTRGVLDVDGSLPAYFDGDIYMKNKKLLDIFYPVGVIYESTSSTSPATIMGGTWERFGNGRVLVGVSENESEFNSVNQSGGSKTHTLTIDEMPSHSHAQYVTANNGSGAIRRDHSSDGSSSLYPQGNNTGNTGGGKPHNNLQPYVTVYRWRRTA
>NZ_CP021867.1|WP_000661350.1|774795_775194_+|phage-holin-family-protein
MKELLATNKVLFSAIGGLIGSIFGEVDGFLFALMVFISIDYITGLMAAAVEKKLASNIGFKGIFKKIVLLFLVAVGQIIDEHVLKQGGVVRTAIIFYYLSNEGLSIIENAARIGLPVPEKLKDVLKQLKQGD
>NZ_CP021867.1|WP_000123549.1|776737_776845_+|putative-holin-like-toxin
MTAFEVVQIIIGFGSFTVALIGLCYKIFKDDDKKK
>NZ_CP021867.1|WP_000290966.1|777152_778394_+|recombinase-family-protein
MAVRLIKTKSNRKKQRVCAYTRVSTTNSSQLDSLENQKAYFENLYTNRVDVDFLGVYYDKGISGSKAERPSFQAMLEACRQGQIDLIHTKSISRFARNTMTVLEVSRELKVLGVGIYFEEQNINTLSNEGEVMLSVLASLAEEELQSMSDNQRWAFQRKFQRGEMVINTKRFMGYDVDDKGELVINEAEAQIVRRIFQLYLDGMGMHRIAKLLNQENVPTVTDAKWHDTTVRNILKNEKYKGTVLLQKYFHVGINGPKRLNQGQVEQYLIEDNHEPIVSKEVWQAVQDKLASKTWKQGVNKHYRFTSMLKCEYCGSTLKRQVTYKKQIVWCCSKYIKEGKASCRGMRVPEKAIEEWKLKTPVTVIERNEYGQKHYSYSSQESAADGHPSASNQNKSGSLLSGVHRPRRTAIKL
>NZ_CP021867.1|WP_172396919.1|778296_779643_+|recombinase-family-protein
MQLTVTHQQATKIRVAAYCRVSTDQDEQLSSYENQVSYYRDYILKHEDYELVDIYADEGISATNTKKREAFNRLIQDCRAGKVDRILVKSISRFARNTLDCIKYVRELKELGIGVTFEKENIDSLDSKGEVLLTILSSLAQDESRSISENATWGIRKKFERGEVRVNTTKFMGYDKDENSRLVINPEQANVVKHIYNQFLDGFGPESIAKEFNAKGIKGWSGKANWYPSAILKMLQNEKYKGDALLQKTYTVDFLTKKRTENTGQVNQYYVANNHEAIISKELWETVQLEIARRKAFREEHKLVFYIMQSDDNPFTTKVFCAECGSAFGRKNWTTSRGKRKVWQCNNRYKVKGQIGCQNNHIDEEMLEKAFLKAVELLQEHRADVVVKWQKLEKGTNLLHKHYAKQMYQLLELDVFDGTIMNQVLDHIIISENGQISVKFLEGTEIDL
>NZ_CP021867.1|WP_000132373.1|779725_780796_+|hypothetical-protein
MTDSNEVKKVERDSIKIAVDSVANLSEKIKLGQNTAAISVLADTLSNFQATVASSNISGFIAASNALTTSKLVNIANLTTPLASLTSSIQMEKSAINAMSEVIDSYNKIWSSAHLQAIQNIAESSKKLIASYQIDYSKIFSNINELLKSLPSTYTQEEIEQITSGVQLLAENGWVIYFRDRNVYQRVLAEEWDVLEEEWVELLRENLKDETSIVDLQNSPCYSDPLVKSMVDCYLNQNYYAAYTLGSLAIDGALNRISEMISSRKKIPVGYKAVEEIDAIFIDKSFSDIGLMHWLYNFFKDTNRFTLDEPNRHMVGHGRWEKEIDETDFLKLFNTLLYIYDEYGYWSEIIETDRLK
>NZ_CP021867.1|WP_000672531.1|780817_782116_+|hypothetical-protein
MKFSKIFKIILLLTGLVLSLLFWKILVNLVVSTNIEVSQGNLYLLAIIFWLELLFLLAIYDLVIIELYSGISYYLSKLGQLAVRTKKVRLALYIIRLNYYLLRLSKLLRIGWVTYGSGEKSSVWIGLSKLSLTQLSLNIFKLVISAPMLLAFLSACFSLKILRGGDIINYLSKHQEFLRGILQLKVNIGDVFSRLPAFVALMTILPVVFFFYFFSQKRDVRKIIDKENSQYFEEVVLLYEKLLIWIDNHIYKLSENFDYVIKCQDSIVEVFLKKEIRNYIELIDKRYYIPRRIEEFRFIEIADLTELREIITKLTSDRLVKFTRIFSVKQFDIWYLYFGDFHTLREEERVEMSFCTKTGISSKLDKRHTYPYDFTQGQIEKRRNEELSLLSWSIYDSLELLYRLKRTSDSLRKYLYSSRTERLILKALSKDK
>NZ_CP021867.1|WP_001142755.1|782333_782555_+|hypothetical-protein
MPTMQLLDELVLPKDITIADVSQSIQEFEIERDALQEFFDDMLKTYTTYQEMKDYIKSREANTPKQETEEKSL

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Crispr_ID: NZ_CP021867_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021867_2

1064343-1065235

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRT

13 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP021867_2

>merge|NZ_CP021867|2|1064343-1065235|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCCGTTCAATCTGTTCTTGCTTTTGGTCATCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAAGGGTGTTAGATGATAATACCTTTTTTAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACACACCGTTGCGGTTGTTGTCGGTCACTCAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTGAAAACAAGCGCAAAGCTGTCAGAAAACAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAGTTATCAATGCTATATGGTTTCTCATCTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGTTTAATTTTGAATAATATCATGTTTACTCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTATGTCATTGTGATTGTGGGAATACTTGTGGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGGCGAACTTGTAACGTTTGACGGTAATTTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTCCTTTTTTAGATAATGTGCGATCACGGACGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTTTTACCAATGCTTCCATATCGCTTATATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTCCTTTTTTAGATAATGTGCGATCACGGACGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTGGTTATACATTTACTAATCCATCAGCATTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAAGCTAATTCTCATCTCACCGAGATGGATAGTTTTAGAGCTGTGCTGTTATTATGCTAGGACATCA

>NZ_CP021867|2|1|1064343-1065169|PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCGTTCAATCTGTTCTTGCTTTTGGTCATC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAGGGTGTTAGATGATAATACCTTTTTTAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACACCGTTGCGGTTGTTGTCGGTCACTCAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGAAAACAAGCGCAAAGCTGTCAGAAAACA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AGTTATCAATGCTATATGGTTTCTCATCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GTTTAATTTTGAATAATATCATGTTTACTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATGTCATTGTGATTGTGGGAATACTTGTG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GGCGAACTTGTAACGTTTGACGGTAATTTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCCTTTTTTAGATAATGTGCGATCACGGAC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTTTACCAATGCTTCCATATCGCTTATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCCTTTTTTAGATAATGTGCGATCACGGAC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGGTTATACATTTACTAATCCATCAGCATT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_CP021867|2|1|1064343-1065169|CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCGTTCAATCTGTTCTTGCTTTTGGTCATC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAGGGTGTTAGATGATAATACCTTTTTTAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACACCGTTGCGGTTGTTGTCGGTCACTCAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGAAAACAAGCGCAAAGCTGTCAGAAAACA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AGTTATCAATGCTATATGGTTTCTCATCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GTTTAATTTTGAATAATATCATGTTTACTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATGTCATTGTGATTGTGGGAATACTTGTG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GGCGAACTTGTAACGTTTGACGGTAATTTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCCTTTTTTAGATAATGTGCGATCACGGAC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTTTACCAATGCTTCCATATCGCTTATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCCTTTTTTAGATAATGTGCGATCACGGAC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGGTTATACATTTACTAATCCATCAGCATT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_CP021867|2|2|1064343-1065235|CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCGTTCAATCTGTTCTTGCTTTTGGTCATC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAGGGTGTTAGATGATAATACCTTTTTTAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACACCGTTGCGGTTGTTGTCGGTCACTCAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGAAAACAAGCGCAAAGCTGTCAGAAAACA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AGTTATCAATGCTATATGGTTTCTCATCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GTTTAATTTTGAATAATATCATGTTTACTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATGTCATTGTGATTGTGGGAATACTTGTG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GGCGAACTTGTAACGTTTGACGGTAATTTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCCTTTTTTAGATAATGTGCGATCACGGAC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTTTACCAATGCTTCCATATCGCTTATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCCTTTTTTAGATAATGTGCGATCACGGAC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGGTTATACATTTACTAATCCATCAGCATT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAGCTAATTCTCATCTCACCGAGATGGATA
GTTTTAGAGCTGTGCTGTTATTATGCTAGGACATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021867.1\|WP_000929489.1\|1062383_1063253_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP021867.1\|WP_001241816.1\|1054121_1054502_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
NZ_CP021867.1\|WP_000523795.1\|1055727_1056465_+\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_CP021867.1\|WP_000065321.1\|1075666_1076770_+\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_CP021867.1\|WP_000621142.1\|1071824_1072289_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP021867.1\|WP_000653357.1\|1057225_1057882_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_CP021867.1\|WP_000122194.1\|1063249_1063591_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP021867.1\|WP_000159234.1\|1053725_1054097_+\|YbgA-family-protein	unknown	unknown	gnl\|CDD\|377982
NZ_CP021867.1\|WP_000168898.1\|1072874_1075667_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_CP021867.1\|WP_000590705.1\|1063577_1064243_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	pfam09711_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP021867.1\|WP_000323544.1\|1056465_1057236_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP021867.1\|WP_001056394.1\|1078239_1078851_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP021867.1\|WP_000665410.1\|1072288_1072723_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP021867.1\|WP_001019133.1\|1066344_1068177_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP021867.1\|WP_000678300.1\|1068423_1071057_+\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|380193
NZ_CP021867.1\|WP_000914664.1\|1054593_1055724_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP021867.1\|WP_000438314.1\|1065792_1066209_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP021867.1\|WP_000146565.1\|1076890_1077529_-\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_CP021867.1\|WP_001040087.1\|1058269_1062382_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
NZ_CP021867.1\|WP_000180005.1\|1071156_1071816_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336

Protein	Function_ID	Function_description	E-value
NZ_CP021867.1\|WP_000929489.1\|1062383_1063253_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.54315e-139
NZ_CP021867.1\|WP_001241816.1\|1054121_1054502_+\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
NZ_CP021867.1\|WP_000523795.1\|1055727_1056465_+\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
NZ_CP021867.1\|WP_000065321.1\|1075666_1076770_+\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.82724e-105
NZ_CP021867.1\|WP_000621142.1\|1071824_1072289_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.91796e-19
NZ_CP021867.1\|WP_000653357.1\|1057225_1057882_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.75792e-52
NZ_CP021867.1\|WP_000122194.1\|1063249_1063591_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.38084e-52
NZ_CP021867.1\|WP_000159234.1\|1053725_1054097_+\|YbgA-family-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	6.08694e-28
NZ_CP021867.1\|WP_000168898.1\|1072874_1075667_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_CP021867.1\|WP_000590705.1\|1063577_1064243_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.28312e-121
NZ_CP021867.1\|WP_000323544.1\|1056465_1057236_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
NZ_CP021867.1\|WP_001056394.1\|1078239_1078851_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	6.1265e-31
NZ_CP021867.1\|WP_000665410.1\|1072288_1072723_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	6.40832e-86
NZ_CP021867.1\|WP_001019133.1\|1066344_1068177_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP021867.1\|WP_000678300.1\|1068423_1071057_+\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	1.69351e-21
NZ_CP021867.1\|WP_000914664.1\|1054593_1055724_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP021867.1\|WP_000438314.1\|1065792_1066209_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	4.64422e-78
NZ_CP021867.1\|WP_000146565.1\|1076890_1077529_-\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	6.8383e-72
NZ_CP021867.1\|WP_001040087.1\|1058269_1062382_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	0
NZ_CP021867.1\|WP_000180005.1\|1071156_1071816_+\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	5.44358e-33

>NZ_CP021867.1|WP_000590705.1|1063577_1064243_+|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMLVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEIKILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>NZ_CP021867.1|WP_000122194.1|1063249_1063591_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGNITLLTVTEKQFARMVYLHGERNTSVANSDSRLVFLGDSYDQD
>NZ_CP021867.1|WP_000929489.1|1062383_1063253_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLEPFDPSNREGHAARIYFNTLFGNDFSREQDNPINAGLDYGYSLLLSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYNGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>NZ_CP021867.1|WP_001040087.1|1058269_1062382_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGWSIITDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTAADRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEEDKRGSKYPIFATLQEEKDYHEKFSTIYHLRKELADKKEKADLRLIYIALAHIIKFRGHFLIEDDSFDVRNTDISKQYQDFLEIFNTTFENNDLLSQNVDVEAILTDKISKSAKKDRILAQYPNQKSTGIFAEFLKLIVGNQADFKKYFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSAAKKLYDSVLLSGILTVIDLSTKAPLSASMIQRYDEHREDLKQLKQFVKASLPEKYQEIFADSSKDGYAGYIEGKTNQEAFYKYLSKLLTKQEDSENFLEKIKNEDFLRKQRTFDNGSIPHQVHLTELKAIIRRQSEYYPFLKENQDRIEKILTFRIPYYIGPLAREKSDFAWMTRKTDDSIRPWNFEDLVDKEKSAEAFIHRMTNNDFYLPEEKVLPKHSLIYEKFTVYNELTKVRYKNEQGETYFFDSNIKQEIFDGVFKEHRKVSKKKLLDFLAKEYEEFRIVDVIGLDKENKAFNASLGTYHDLEKILDKDFLDNPDNESILEDIVQTLTLFEDREMIKKRLENYKDLFTESQLKKLYRRHYTGWGRLSAKLINGIRDKESQKTILDYLIDDGRSNRNFMQLINDDGLSFKSIISKAQAGSHSDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQIVVEMARENQTTNQGRRNSRQRYKLLDDGVKNLASDLNGNILKEYPTDNQALQNERLFLYYLQNGRDMYTGEALDIDNLSQYDIDHIIPQAFIKDDSIDNRVLVSSAKNRGKSDDVPSLEIVKDCKVFWKKLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNELDSKGRRIRKVKIVTLKSNLVSNFRKEFGFYKIREVNNYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGDYPKYNSYKTRKSATEKLFFYSNIMNFFKTKVTLADGTVVVKDDIEVNNDTGEIVWDKKKHFATVRKVLSYPQNNIVKKTEIQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERSRFEKNPSAFLESKGYLNIRADKLIILPKYSLFELENGRRRLLASAGELQKGNELALPTQFMKFLYLASRYNESKGKPEEIEKKQEFVNQHVSYFDDILQLINDFSKRVILADANLEKINKLYQDNKENISVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGED
>NZ_CP021867.1|WP_000653357.1|1057225_1057882_+|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRRGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>NZ_CP021867.1|WP_000323544.1|1056465_1057236_+|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>NZ_CP021867.1|WP_000523795.1|1055727_1056465_+|acyl-ACP-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>NZ_CP021867.1|WP_000914664.1|1054593_1055724_+|oxygen-independent-coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELSRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEAQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWDNVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKEGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>NZ_CP021867.1|WP_001241816.1|1054121_1054502_+|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>NZ_CP021867.1|WP_000159234.1|1053725_1054097_+|YbgA-family-protein
MTKEAELLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE
>NZ_CP021867.1|WP_000438314.1|1065792_1066209_+|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRYADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESATREIAIWFNN
>NZ_CP021867.1|WP_001019133.1|1066344_1068177_+|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>NZ_CP021867.1|WP_000678300.1|1068423_1071057_+|pneumococcal-type-histidine-triad-protein
MKGQKIIALAGLVLSCHFALTACHTQEHKNSHHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANTKTNKNQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQSNSHYRVNSSKIAGLHYPTSNGFLFNGRGIKGTTPTGILVEHHNHLHFISFADLRKGGWGSIADRYQPQKKADSKKQSPSSKKPRTENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDEDQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELYLDHNNVKNLSALSGKKDLKVLDLSNNKSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLASLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSKNKLESLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEDKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>NZ_CP021867.1|WP_000180005.1|1071156_1071816_+|HD-domain-containing-protein
MTMVKREDVILNATENMVHHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMAALLHDIIDDKICQDSKQASYELTQWLYSQDLAIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIIHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKR
>NZ_CP021867.1|WP_000621142.1|1071824_1072289_+|GNAT-family-N-acetyltransferase
MIRRAKEKDLPDIAELLKQILMLHHEVRPDIFHTRGSKFSKEQLKEMLIDESKPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>NZ_CP021867.1|WP_000665410.1|1072288_1072723_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFD
>NZ_CP021867.1|WP_000168898.1|1072874_1075667_+|cation-transporting-P-type-ATPase
MASTNNVSDTNTRFAKEELEEVFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVKQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALEKMLPSYSRVLRKGSEEKILSEQLVPGDIVLIEEGDRISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENDQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNHLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDDRSTYTVLGDPTEACLNVLLEKSGINIQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILDLSDYVLSDGKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDDAKVISGLELSEMTDSQLKKELSGEVVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIKALSIFGNKLINFGIIMEILAFLVLVYVPLFHNLFNTASLGLSHWLYLISCPFIMIGLDEVRKLFSSRKNKR
>NZ_CP021867.1|WP_000065321.1|1075666_1076770_+|DUF2974-domain-containing-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYRAEISLEFEKQFAAMVFTIPNINYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGTGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFWGAYHDNSRETK
>NZ_CP021867.1|WP_000146565.1|1076890_1077529_-|CatB-related-O-acetyltransferase
MASILKKHLEKRLELKNDPMRTDMSTGASYPKYGFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGLNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIGAGSVITKDIPDYAVVAGTPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKKEFFNTLKSISENKNHKL
>NZ_CP021867.1|WP_001056394.1|1078239_1078851_+|TVP38/TMEM64-family-protein
MNMKLSKRYRFWQKVIKALGVLALIATLVLVVYLYKLGILNDSNELKDLVHKYEFWGPMIFIVAQIVQIVFPVIPGGVTTVAGFLIFGPTLGFIYNYIGIIIGSVILFWLVKFYGRKFVLLFMDQKTFDKYESKLETSGYEKFFIFCMASPISPADIMVMITGLSNMSIKRFVTIIMITKPISIIGYSYLWIYGGDILKNFLN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	NZ_CP021867.1	414372-414401	2	0.933

1. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to position: 414372-414401, mismatch: 2, identity: 0.933

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaatctgttcttgcttttgctcgtc	Protospacer
************************ **.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448726	Streptococcus phage Javan29, complete genome	26537-26583	0	1.0
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448726	Streptococcus phage Javan29, complete genome	26603-26649	0	1.0
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448726	Streptococcus phage Javan29, complete genome	26669-26715	0	1.0
NZ_CP021867_2	2.3\|1064511\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064511-1064540	30	MK448956	Streptococcus phage Javan48, complete genome	2174-2203	0	1.0
NZ_CP021867_2	2.3\|1064511\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064511-1064540	30	MK448749	Streptococcus phage Javan39, complete genome	2174-2203	0	1.0
NZ_CP021867_2	2.3\|1064511\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064511-1064540	30	MH853356	Streptococcus phage LF2, partial genome	18636-18665	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448829	Streptococcus phage Javan7, complete genome	16033-16062	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448736	Streptococcus phage Javan35, complete genome	16516-16545	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448781	Streptococcus phage Javan5, complete genome	18538-18567	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MH853355	Streptococcus phage LF1, complete genome	6890-6919	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448911	Streptococcus phage Javan34, complete genome	16516-16545	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448837	Streptococcus phage Javan10, complete genome	14562-14591	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448742	Streptococcus phage Javan37, complete genome	16352-16381	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MH853358	Streptococcus phage LF4, complete genome	6890-6919	0	1.0
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448916	Streptococcus phage Javan36, complete genome	16516-16545	0	1.0
NZ_CP021867_2	2.8\|1064841\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064841-1064870	30	MH853356	Streptococcus phage LF2, partial genome	8933-8962	0	1.0
NZ_CP021867_2	2.8\|1064841\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064841-1064870	30	MK448971	Streptococcus phage Javan52, complete genome	11470-11499	0	1.0
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448928	Streptococcus phage Javan40, complete genome	26645-26691	1	0.979
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448728	Streptococcus phage Javan3, complete genome	26649-26695	1	0.979
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448809	Streptococcus phage Javan57, complete genome	26645-26691	1	0.979
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448872	Streptococcus phage Javan20, complete genome	26645-26691	1	0.979
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448802	Streptococcus phage Javan55, complete genome	26645-26691	1	0.979
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448999	Streptococcus phage Javan638, complete genome	24540-24586	1	0.979
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448776	Streptococcus phage Javan49, complete genome	26537-26583	1	0.979
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK449007	Streptococcus phage Javan8, complete genome	26523-26569	1	0.979
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448787	Streptococcus phage Javan51, complete genome	26523-26569	1	0.979
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448971	Streptococcus phage Javan52, complete genome	5153-5182	1	0.967
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448487	Streptococcus satellite phage Javan419, complete genome	1643-1672	1	0.967
NZ_CP021867_2	2.5\|1064643\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064643-1064672	30	MK448938	Streptococcus phage Javan44, complete genome	16517-16546	1	0.967
NZ_CP021867_2	2.8\|1064841\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064841-1064870	30	MK448796	Streptococcus phage Javan53, complete genome	13207-13236	1	0.967
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448695	Streptococcus phage Javan181, complete genome	25465-25511	2	0.957
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448935	Streptococcus phage Javan424, complete genome	26621-26667	2	0.957
NZ_CP021867_1	1.1\|768594\|47\|NZ_CP021867\|CRT	768594-768640	47	MK448936	Streptococcus phage Javan426, complete genome	26621-26667	2	0.957
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448668	Streptococcus phage Javan107, complete genome	26538-26584	2	0.957
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448666	Streptococcus phage Javan101, complete genome	26538-26584	2	0.957
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448840	Streptococcus phage Javan104, complete genome	26538-26584	2	0.957
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448670	Streptococcus phage Javan113, complete genome	26487-26533	2	0.957
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448854	Streptococcus phage Javan146, complete genome	6052-6081	2	0.933
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448851	Streptococcus phage Javan14, complete genome	4829-4858	2	0.933
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448928	Streptococcus phage Javan40, complete genome	26777-26823	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448728	Streptococcus phage Javan3, complete genome	26781-26827	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK449011	Streptococcus phage Javan92, complete genome	26163-26209	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448835	Streptococcus phage Javan93, complete genome	26163-26209	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448836	Streptococcus phage Javan95, complete genome	27238-27284	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448809	Streptococcus phage Javan57, complete genome	26777-26823	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448872	Streptococcus phage Javan20, complete genome	26777-26823	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448825	Streptococcus phage Javan639, complete genome	27238-27284	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448802	Streptococcus phage Javan55, complete genome	26777-26823	3	0.936
NZ_CP021867_1	1.3\|768726\|47\|NZ_CP021867\|CRT	768726-768772	47	MK448999	Streptococcus phage Javan638, complete genome	24672-24718	3	0.936
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448796	Streptococcus phage Javan53, complete genome	5477-5506	3	0.9
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448928	Streptococcus phage Javan40, complete genome	26711-26757	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448922	Streptococcus phage Javan38, complete genome	26405-26451	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448728	Streptococcus phage Javan3, complete genome	26715-26761	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448717	Streptococcus phage Javan25, complete genome	26405-26451	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448906	Streptococcus phage Javan32, complete genome	26405-26451	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448836	Streptococcus phage Javan95, complete genome	27172-27218	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448809	Streptococcus phage Javan57, complete genome	26711-26757	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448827	Streptococcus phage Javan65, complete genome	26405-26451	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448872	Streptococcus phage Javan20, complete genome	26711-26757	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448825	Streptococcus phage Javan639, complete genome	27172-27218	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448802	Streptococcus phage Javan55, complete genome	26711-26757	4	0.915
NZ_CP021867_1	1.2\|768660\|47\|NZ_CP021867\|CRT	768660-768706	47	MK448999	Streptococcus phage Javan638, complete genome	24606-24652	4	0.915
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448363	Streptococcus satellite phage Javan21, complete genome	1744-1773	4	0.867
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448502	Streptococcus satellite phage Javan45, complete genome	1744-1773	4	0.867
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448541	Streptococcus satellite phage Javan56, complete genome	1744-1773	4	0.867
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448549	Streptococcus satellite phage Javan58, complete genome	1744-1773	4	0.867
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448412	Streptococcus satellite phage Javan30, complete genome	1744-1773	4	0.867
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448479	Streptococcus satellite phage Javan41, complete genome	1744-1773	4	0.867
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448472	Streptococcus satellite phage Javan4, complete genome	1744-1773	4	0.867
NZ_CP021867_2	2.4\|1064577\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064577-1064606	30	MK448796	Streptococcus phage Javan53, complete genome	30266-30295	4	0.867
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448393	Streptococcus satellite phage Javan276, complete genome	10967-10996	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448491	Streptococcus satellite phage Javan43, complete genome	3439-3468	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448327	Streptococcus satellite phage Javan13, complete genome	3439-3468	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448380	Streptococcus satellite phage Javan24, complete genome	3439-3468	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448322	Streptococcus satellite phage Javan12, complete genome	3439-3468	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK448824	Streptococcus phage Javan637, complete genome	5897-5926	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK449002	Streptococcus phage Javan642, complete genome	5897-5926	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MK449003	Streptococcus phage Javan648, complete genome	5897-5926	5	0.833
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	AP018278	Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome	31346-31375	6	0.8
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_LR134418	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9	292766-292795	6	0.8
NZ_CP021867_2	2.12\|1065104\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1065104-1065133	30	NC_047897	Lactobacillus phage Lenus, complete genome	65427-65456	6	0.8
NZ_CP021867_2	2.12\|1065104\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1065104-1065133	30	AP013698	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C55A-MedDCM-OCT-S36-C68, * SEQUENCING IN PROGRESS *	17874-17903	6	0.8
NZ_CP021867_2	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	MF140432	Arthrobacter phage Teacup, complete genome	55361-55390	7	0.767
NZ_CP021867_2	2.2\|1064445\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064445-1064474	30	NZ_CP023411	Clostridium perfringens strain LLY_N11 plasmid pLLY_N11_1, complete sequence	11441-11470	7	0.767
NZ_CP021867_2	2.3\|1064511\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064511-1064540	30	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	465384-465413	7	0.767
NZ_CP021867_2	2.12\|1065104\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1065104-1065133	30	NC_047925	Lactobacillus phage Nyseid, complete genome	67879-67908	7	0.767
NZ_CP021867_2	2.12\|1065104\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1065104-1065133	30	KU052488	Lactobacillus phage SA-C12, complete genome	24549-24578	7	0.767
NZ_CP021867_2	2.12\|1065104\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1065104-1065133	30	MN693473	Marine virus AFVG_25M504, complete genome	22237-22266	7	0.767
NZ_CP021867_2	2.2\|1064445\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064445-1064474	30	NZ_CP027854	Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-2, complete sequence	18490-18519	8	0.733
NZ_CP021867_2	2.2\|1064445\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064445-1064474	30	NZ_CP013043	Clostridium perfringens strain JP55 plasmid pJFP55H, complete sequence	44939-44968	8	0.733
NZ_CP021867_2	2.3\|1064511\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064511-1064540	30	NC_047866	Aeromonas phage Ahp1, complete genome	4717-4746	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	89228-89257	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	22382-22411	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	110578-110607	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP007453	Peptoclostridium acidaminophilum DSM 3953 strain al-2 plasmid EAL2_808p, complete sequence	1807-1836	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP014929	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-5, complete sequence	4518-4547	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	544241-544270	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	715248-715277	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	544290-544319	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	715264-715293	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	645889-645918	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	LR746310	Klebsiella phage vB_KpnM_05F genome assembly, chromosome: 1	125568-125597	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	MT157285	Klebsiella phage P-KP2, complete genome	148204-148233	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	HQ918180	Klebsiella phage KP27, complete genome	111147-111176	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	KT001918	Klebsiella phage Matisse, complete genome	114145-114174	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	KX130727	Escherichia phage phT4A, partial genome	106647-106676	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	KT321315	Enterobacter phage phiEap-3, complete genome	112834-112863	8	0.733
NZ_CP021867_2	2.6\|1064709\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064709-1064738	30	MN101221	Klebsiella phage KOX8, complete genome	120508-120537	8	0.733
NZ_CP021867_2	2.12\|1065104\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1065104-1065133	30	AP018932	Escherichia phage KIT03 DNA, complete sequence	154828-154857	8	0.733
NZ_CP021867_2	2.3\|1064511\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064511-1064540	30	NZ_CP029363	Streptomyces globisporus strain TFH56 plasmid pTFSG2, complete sequence	29181-29210	9	0.7
NZ_CP021867_2	2.3\|1064511\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064511-1064540	30	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	715552-715581	9	0.7

1. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448726 (Streptococcus phage Javan29, complete genome) position: , mismatch: 0, identity: 1.0

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	Protospacer
***********************************************

2. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448726 (Streptococcus phage Javan29, complete genome) position: , mismatch: 0, identity: 1.0

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatcgagtattggttcaacggtatcttcta	Protospacer
***********************************************

3. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448726 (Streptococcus phage Javan29, complete genome) position: , mismatch: 0, identity: 1.0

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	Protospacer
***********************************************

4. spacer 2.3|1064511|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

acaccgttgcggttgttgtcggtcactcaa	CRISPR spacer
acaccgttgcggttgttgtcggtcactcaa	Protospacer
******************************

5. spacer 2.3|1064511|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 0, identity: 1.0

acaccgttgcggttgttgtcggtcactcaa	CRISPR spacer
acaccgttgcggttgttgtcggtcactcaa	Protospacer
******************************

6. spacer 2.3|1064511|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

acaccgttgcggttgttgtcggtcactcaa	CRISPR spacer
acaccgttgcggttgttgtcggtcactcaa	Protospacer
******************************

7. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448829 (Streptococcus phage Javan7, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

8. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

9. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

10. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MH853355 (Streptococcus phage LF1, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

11. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

12. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

13. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

14. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MH853358 (Streptococcus phage LF4, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

15. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttctcatctt	Protospacer
******************************

16. spacer 2.8|1064841|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

ggcgaacttgtaacgtttgacggtaatttt	CRISPR spacer
ggcgaacttgtaacgtttgacggtaatttt	Protospacer
******************************

17. spacer 2.8|1064841|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

ggcgaacttgtaacgtttgacggtaatttt	CRISPR spacer
ggcgaacttgtaacgtttgacggtaatttt	Protospacer
******************************

18. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448928 (Streptococcus phage Javan40, complete genome) position: , mismatch: 1, identity: 0.979

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
caccatgacaaacttactaaatagtatcaaatctgtcgttagtaatg	Protospacer
****************** ****************************

19. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448728 (Streptococcus phage Javan3, complete genome) position: , mismatch: 1, identity: 0.979

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
caccatgacaaacttactaaatagtatcaaatctgtcgttagtaatg	Protospacer
****************** ****************************

20. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448809 (Streptococcus phage Javan57, complete genome) position: , mismatch: 1, identity: 0.979

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
caccatgacaaacttactaaatagtatcaaatctgtcgttagtaatg	Protospacer
****************** ****************************

21. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448872 (Streptococcus phage Javan20, complete genome) position: , mismatch: 1, identity: 0.979

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
caccatgacaaacttactaaatagtatcaaatctgtcgttagtaatg	Protospacer
****************** ****************************

22. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448802 (Streptococcus phage Javan55, complete genome) position: , mismatch: 1, identity: 0.979

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
caccatgacaaacttactaaatagtatcaaatctgtcgttagtaatg	Protospacer
****************** ****************************

23. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448999 (Streptococcus phage Javan638, complete genome) position: , mismatch: 1, identity: 0.979

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
caccatgacaaacttactcaatagtatcaaatctgtcgttagtaatg	Protospacer
******************.****************************

24. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448776 (Streptococcus phage Javan49, complete genome) position: , mismatch: 1, identity: 0.979

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
aacgattagttccattctatcgagtattggttcaacggtatcttcta	Protospacer
 **********************************************

25. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK449007 (Streptococcus phage Javan8, complete genome) position: , mismatch: 1, identity: 0.979

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
aacgattagttccattctatcgagtattggttcaacggtatcttcta	Protospacer
 **********************************************

26. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448787 (Streptococcus phage Javan51, complete genome) position: , mismatch: 1, identity: 0.979

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
aacgattagttccattctatcgagtattggttcaacggtatcttcta	Protospacer
 **********************************************

27. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 1, identity: 0.967

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
gcgttcaatctgttcttgcttttggtcatc	Protospacer
 *****************************

28. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448487 (Streptococcus satellite phage Javan419, complete genome) position: , mismatch: 1, identity: 0.967

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaagctgttcttgcttttggtcatc	Protospacer
******** *********************

29. spacer 2.5|1064643|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 1, identity: 0.967

agttatcaatgctatatggtttctcatctt	CRISPR spacer
agttatcaatgctatatggtttttcatctt	Protospacer
**********************.*******

30. spacer 2.8|1064841|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 1, identity: 0.967

ggcgaacttgtaacgtttgacggtaatttt	CRISPR spacer
ggcgaacttgtaacttttgacggtaatttt	Protospacer
************** ***************

31. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448695 (Streptococcus phage Javan181, complete genome) position: , mismatch: 2, identity: 0.957

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
cagcatgacaaacttactcaatagtatcaaatctgtcgttagtaatg	Protospacer
** ***************.****************************

32. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448935 (Streptococcus phage Javan424, complete genome) position: , mismatch: 2, identity: 0.957

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
cactatgacaaacttactcaatagtatcaaatctgtcgttagtaatg	Protospacer
***.**************.****************************

33. spacer 1.1|768594|47|NZ_CP021867|CRT matches to MK448936 (Streptococcus phage Javan426, complete genome) position: , mismatch: 2, identity: 0.957

caccatgacaaacttacttaatagtatcaaatctgtcgttagtaatg	CRISPR spacer
cactatgacaaacttactcaatagtatcaaatctgtcgttagtaatg	Protospacer
***.**************.****************************

34. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448668 (Streptococcus phage Javan107, complete genome) position: , mismatch: 2, identity: 0.957

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
aaccatctcaggtgtcctaagtggtatttcaagcacagtgtcctctg	Protospacer
********************************.******* ******

35. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448666 (Streptococcus phage Javan101, complete genome) position: , mismatch: 2, identity: 0.957

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
aaccatctcaggtgtcctaagtggtatttcaagcacagtgtcctctg	Protospacer
********************************.******* ******

36. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448840 (Streptococcus phage Javan104, complete genome) position: , mismatch: 2, identity: 0.957

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
aaccatctcaggtgtcctaagtggtatttcaagcacagtgtcctctg	Protospacer
********************************.******* ******

37. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448670 (Streptococcus phage Javan113, complete genome) position: , mismatch: 2, identity: 0.957

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
aaccatctcaggtgtcctaagtggtatttcaagcacagtgtcctctg	Protospacer
********************************.******* ******

38. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 2, identity: 0.933

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
gcgttcaatctgttcttgctttttgtcatc	Protospacer
 ********************** ******

39. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 2, identity: 0.933

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaagctgttctcgcttttggtcatc	Protospacer
******** *******.*************

40. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448928 (Streptococcus phage Javan40, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

41. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448728 (Streptococcus phage Javan3, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

42. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK449011 (Streptococcus phage Javan92, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

43. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448835 (Streptococcus phage Javan93, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

44. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

45. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448809 (Streptococcus phage Javan57, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

46. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448872 (Streptococcus phage Javan20, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

47. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

48. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448802 (Streptococcus phage Javan55, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

49. spacer 1.3|768726|47|NZ_CP021867|CRT matches to MK448999 (Streptococcus phage Javan638, complete genome) position: , mismatch: 3, identity: 0.936

aaccatctcaggtgtcctaagtggtatttcaaacacagtgacctctg	CRISPR spacer
tactatctcaggtgtcctaagtggtatttcaaacacagtgtcctctg	Protospacer
 **.************************************ ******

50. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 3, identity: 0.9

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
gcgttcaatctgttcttgcttttgctcgtc	Protospacer
 *********************** **.**

51. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448928 (Streptococcus phage Javan40, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

52. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448922 (Streptococcus phage Javan38, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

53. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448728 (Streptococcus phage Javan3, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

54. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448717 (Streptococcus phage Javan25, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

55. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448906 (Streptococcus phage Javan32, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

56. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatcgagtattggcgcaacggtatcttccg	Protospacer
******************************. *************..

57. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448809 (Streptococcus phage Javan57, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

58. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448827 (Streptococcus phage Javan65, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

59. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448872 (Streptococcus phage Javan20, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

60. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatcgagtattggcgcaacggtatcttccg	Protospacer
******************************. *************..

61. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448802 (Streptococcus phage Javan55, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

62. spacer 1.2|768660|47|NZ_CP021867|CRT matches to MK448999 (Streptococcus phage Javan638, complete genome) position: , mismatch: 4, identity: 0.915

cacgattagttccattctatcgagtattggttcaacggtatcttcta	CRISPR spacer
cacgattagttccattctatctagtattggctcaacggtatcttccg	Protospacer
********************* ********.**************..

63. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448363 (Streptococcus satellite phage Javan21, complete genome) position: , mismatch: 4, identity: 0.867

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttattcaagctgttcttgcttttggtcatc	Protospacer
...***** *********************

64. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448502 (Streptococcus satellite phage Javan45, complete genome) position: , mismatch: 4, identity: 0.867

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttattcaagctgttcttgcttttggtcatc	Protospacer
...***** *********************

65. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448541 (Streptococcus satellite phage Javan56, complete genome) position: , mismatch: 4, identity: 0.867

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttattcaagctgttcttgcttttggtcatc	Protospacer
...***** *********************

66. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448549 (Streptococcus satellite phage Javan58, complete genome) position: , mismatch: 4, identity: 0.867

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttattcaagctgttcttgcttttggtcatc	Protospacer
...***** *********************

67. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448412 (Streptococcus satellite phage Javan30, complete genome) position: , mismatch: 4, identity: 0.867

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttattcaagctgttcttgcttttggtcatc	Protospacer
...***** *********************

68. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448479 (Streptococcus satellite phage Javan41, complete genome) position: , mismatch: 4, identity: 0.867

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttattcaagctgttcttgcttttggtcatc	Protospacer
...***** *********************

69. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448472 (Streptococcus satellite phage Javan4, complete genome) position: , mismatch: 4, identity: 0.867

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttattcaagctgttcttgcttttggtcatc	Protospacer
...***** *********************

70. spacer 2.4|1064577|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 4, identity: 0.867

tgaaaacaagcgcaaagctgtcagaaaaca	CRISPR spacer
taacaacaagcgtaaagctgtcagaaaaaa	Protospacer
*.* ********.*************** *

71. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448393 (Streptococcus satellite phage Javan276, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
tttttcaagctgttcttgctttgggtcatc	Protospacer
.. ***** ************* *******

72. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448491 (Streptococcus satellite phage Javan43, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
gcaatcaagctgttcttgcttttggttatc	Protospacer
 *. **** *****************.***

73. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448327 (Streptococcus satellite phage Javan13, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
gcaatcaagctgttcttgcttttggttatc	Protospacer
 *. **** *****************.***

74. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448380 (Streptococcus satellite phage Javan24, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
gcaatcaagctgttcttgcttttggttatc	Protospacer
 *. **** *****************.***

75. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448322 (Streptococcus satellite phage Javan12, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
gcaatcaagctgttcttgcttttggttatc	Protospacer
 *. **** *****************.***

76. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK448824 (Streptococcus phage Javan637, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaatctgttcttgcttagcttcgtc	Protospacer
*********************    **.**

77. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK449002 (Streptococcus phage Javan642, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaatctgttcttgcttagcttcgtc	Protospacer
*********************    **.**

78. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MK449003 (Streptococcus phage Javan648, complete genome) position: , mismatch: 5, identity: 0.833

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaatctgttcttgcttagcttcgtc	Protospacer
*********************    **.**

79. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to AP018278 (Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome) position: , mismatch: 6, identity: 0.8

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
cagttcgatctgttcttgctttttaccagc	Protospacer
* ****.**************** ..** *

80. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134418 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9) position: , mismatch: 6, identity: 0.8

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctttaattttgaaaaatatcattttaattt	Protospacer
 ************ ******** ** *.*.

81. spacer 2.12|1065104|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NC_047897 (Lactobacillus phage Lenus, complete genome) position: , mismatch: 6, identity: 0.8

tggttatacatttactaatccatcagcatt	CRISPR spacer
ggatggtactgttactaatccatcagcatt	Protospacer
 *.* .***  *******************

82. spacer 2.12|1065104|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to AP013698 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C55A-MedDCM-OCT-S36-C68, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

-tggttatacatttactaatccatcagcatt	CRISPR spacer
ctcagta-acagttactaatacatcagcatt	Protospacer
 * . ** *** ******** **********

83. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MF140432 (Arthrobacter phage Teacup, complete genome) position: , mismatch: 7, identity: 0.767

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ttgttcaatctgttcttgcttctgctggtg	Protospacer
..*******************.** * .*

84. spacer 2.2|1064445|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023411 (Clostridium perfringens strain LLY_N11 plasmid pLLY_N11_1, complete sequence) position: , mismatch: 7, identity: 0.767

aagggtgttagatgataataccttttttaa	CRISPR spacer
aatctatttagattatgataccttttttaa	Protospacer
**     ****** **.*************

85. spacer 2.3|1064511|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 7, identity: 0.767

acaccgttgcggttgttgtcggtcactcaa---	CRISPR spacer
actccgttgcggtggttgtcggt---gcagagt	Protospacer
** ********** *********    **.

86. spacer 2.12|1065104|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NC_047925 (Lactobacillus phage Nyseid, complete genome) position: , mismatch: 7, identity: 0.767

tggttatacatttactaatccatcagcatt	CRISPR spacer
ggacggtactgttactaatccatcagcatt	Protospacer
 *.. .***  *******************

87. spacer 2.12|1065104|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to KU052488 (Lactobacillus phage SA-C12, complete genome) position: , mismatch: 7, identity: 0.767

tggttatacatttactaatccatcagcatt	CRISPR spacer
ggacggtactgttactaatccatcagcatt	Protospacer
 *.. .***  *******************

88. spacer 2.12|1065104|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MN693473 (Marine virus AFVG_25M504, complete genome) position: , mismatch: 7, identity: 0.767

tggttatacatttactaatccatcagcatt	CRISPR spacer
tggtgatacatttactaatcctatgccatc	Protospacer
**** ****************  .. ***.

89. spacer 2.2|1064445|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027854 (Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-2, complete sequence) position: , mismatch: 8, identity: 0.733

aagggtgttagatgataataccttttttaa	CRISPR spacer
tggggtgttaaatgataaaacctttgatcg	Protospacer
 .********.******* ******  * .

90. spacer 2.2|1064445|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013043 (Clostridium perfringens strain JP55 plasmid pJFP55H, complete sequence) position: , mismatch: 8, identity: 0.733

aagggtgttagatgataataccttttttaa	CRISPR spacer
tcttttgttagatgatatttccttttttta	Protospacer
     ************ * ******** *

91. spacer 2.3|1064511|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NC_047866 (Aeromonas phage Ahp1, complete genome) position: , mismatch: 8, identity: 0.733

acaccgttgcggttgttgtcggtcactcaa	CRISPR spacer
tcatcgttgcggttgtcgtcggtcgtgaca	Protospacer
 **.************.*******..   *

92. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
attttattttgaataatatcatttacatca	Protospacer
.*** ***************** * .*..

93. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
tcttgtttttgaataatatcatctttagat	Protospacer
 .**. **************** ****  .

94. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
tcttgtttttgaataatatcatctttagat	Protospacer
 .**. **************** ****  .

95. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007453 (Peptoclostridium acidaminophilum DSM 3953 strain al-2 plasmid EAL2_808p, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctataatttttaaaaatatcatgtttttat	Protospacer
 * ******* ** ************ . .

96. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014929 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-5, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
atttattttttaataatatcatgtaatttt	Protospacer
.**** **** *************   .*.

97. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
tcttgtttttgaataatatcatctttagat	Protospacer
 .**. **************** ****  .

98. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
tcttgtttttgaataatatcatctttagat	Protospacer
 .**. **************** ****  .

99. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
tcttgtttttgaataatatcatctttagat	Protospacer
 .**. **************** ****  .

100. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
tcttgtttttgaataatatcatctttagat	Protospacer
 .**. **************** ****  .

101. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
tcttgtttttgaataatatcatctttagat	Protospacer
 .**. **************** ****  .

102. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to LR746310 (Klebsiella phage vB_KpnM_05F genome assembly, chromosome: 1) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctatctacttgaataatatcaagtttactg	Protospacer
 * *   .************* *******

103. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MT157285 (Klebsiella phage P-KP2, complete genome) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctatctacttgaataatatcaagtttactg	Protospacer
 * *   .************* *******

104. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to HQ918180 (Klebsiella phage KP27, complete genome) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctatctacttgaataatatcaagtttactg	Protospacer
 * *   .************* *******

105. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to KT001918 (Klebsiella phage Matisse, complete genome) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctatctacttgaataatatcaagtttactg	Protospacer
 * *   .************* *******

106. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to KX130727 (Escherichia phage phT4A, partial genome) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctatctacttgaataatatcaagtttactg	Protospacer
 * *   .************* *******

107. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to KT321315 (Enterobacter phage phiEap-3, complete genome) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctatctacttgaataatatcaagtttactg	Protospacer
 * *   .************* *******

108. spacer 2.6|1064709|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to MN101221 (Klebsiella phage KOX8, complete genome) position: , mismatch: 8, identity: 0.733

gtttaattttgaataatatcatgtttactc	CRISPR spacer
ctatctacttgaataatatcaagtttactg	Protospacer
 * *   .************* *******

109. spacer 2.12|1065104|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to AP018932 (Escherichia phage KIT03 DNA, complete sequence) position: , mismatch: 8, identity: 0.733

tggttatacatttactaatccatcagcatt	CRISPR spacer
gggtaatacatttactaatccaagcgaagg	Protospacer
 *** *****************   * *

110. spacer 2.3|1064511|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029363 (Streptomyces globisporus strain TFH56 plasmid pTFSG2, complete sequence) position: , mismatch: 9, identity: 0.7

acaccgttgcggttgttgtcggtcactcaa	CRISPR spacer
gggccgttgcggatgttgtcggtcagcagc	Protospacer
. .********* ************ . .

111. spacer 2.3|1064511|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 9, identity: 0.7

acaccgttgcggttgttgtcggtcactcaa	CRISPR spacer
acaccgttgcgggagttgtcggtgtagtgc	Protospacer
************  *********    ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

21284 : 29390

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000220683.1\|21284_22739_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.4e-53	32.5
WP_001291337.1\|22766_23789_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	1.2e-62	42.4
WP_000686114.1\|23956_24505_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.0e-25	35.6
WP_000780022.1\|24527_25280_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000166549.1\|25299_26847_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.9e-78	49.2
WP_001045908.1\|27039_27939_+	peptidoglycan DD-metalloendopeptidase family protein	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
WP_000783419.1\|28085_29390_+	LysM peptidoglycan-binding domain-containing protein	A0A2D1GNZ3	Streptomyces_phage	3.7e-05	40.5

DBSCAN-SWA_2

159951 : 212048

Streptococcus_phage(90.0%)

portal,terminase,tRNA,holin,tail,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001019853.1\|159951_161211_-\|tRNA	tyrosine--tRNA ligase	A0A1S6UA79	Serratia_phage	3.1e-73	41.0
WP_000472388.1\|161321_163619_+	penicillin-binding protein	NA	NA	NA	NA
WP_000907191.1\|164142_167718_+	DNA-directed RNA polymerase subunit beta	A0A2P0VMZ3	Tetraselmis_virus	9.8e-40	26.1
WP_000228729.1\|167834_171485_+	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	2.6e-64	25.1
WP_000285373.1\|171598_171964_+	DUF1033 family protein	NA	NA	NA	NA
WP_017285365.1\|172953_174045_+	type II secretion system F family protein	NA	NA	NA	NA
WP_001044789.1\|174118_175573_-	recombinase family protein	K4JU73	Streptococcus_phage	9.8e-180	65.3
WP_000390807.1\|175730_176069_-	hypothetical protein	NA	NA	NA	NA
WP_000200806.1\|176072_176501_-	hypothetical protein	M1PKK7	Streptococcus_phage	1.4e-09	28.4
WP_000823130.1\|176512_177097_-	hypothetical protein	NA	NA	NA	NA
WP_000880827.1\|177099_177297_-	hypothetical protein	B3GVW9	Streptococcus_phage	1.0e-15	56.9
WP_000580170.1\|177315_178056_-	helix-turn-helix transcriptional regulator	J7KJ52	Streptococcus_phage	4.2e-70	57.5
WP_000215930.1\|178209_178431_+	helix-turn-helix transcriptional regulator	A0A1S5S8R4	Streptococcus_phage	5.7e-07	49.1
WP_001074679.1\|178685_178835_+	hypothetical protein	K4JU69	Streptococcus_phage	2.9e-07	76.5
WP_000072970.1\|178874_179207_+	hypothetical protein	K4JW96	Streptococcus_phage	8.5e-31	67.3
WP_000131170.1\|179427_180099_+	ERF family protein	M1IEW6	Streptococcus_phage	3.2e-101	81.7
WP_000159058.1\|180102_181098_+	DUF1351 domain-containing protein	A0A1S5S8J6	Streptococcus_phage	8.3e-98	62.1
WP_001010334.1\|181099_181651_+	MazG-like family protein	M1I9W2	Streptococcus_phage	1.1e-30	46.4
WP_000609569.1\|181741_182215_+	single-stranded DNA-binding protein	M1PL31	Streptococcus_phage	2.7e-54	81.3
WP_001082484.1\|182211_182490_+	hypothetical protein	A0A1S5S8Z6	Streptococcus_phage	6.2e-43	84.8
WP_029667750.1\|182503_183295_+	DNA methyltransferase	U4KJA1	Streptococcus_phage	3.5e-139	89.3
WP_000163592.1\|183281_183485_+	hypothetical protein	A0A1S5SCK3	Streptococcus_phage	1.7e-21	73.1
WP_000862186.1\|183481_183895_+	helix-turn-helix transcriptional regulator	K4JTK7	Streptococcus_phage	2.8e-39	60.7
WP_000412398.1\|183907_184339_+	hypothetical protein	U4KJ68	Streptococcus_phage	5.8e-56	87.5
WP_001293548.1\|184340_185075_+	hypothetical protein	A0A141E1K8	Streptococcus_phage	2.2e-79	62.8
WP_000836878.1\|185717_186044_+	DUF1372 family protein	NA	NA	NA	NA
WP_001019158.1\|186176_186785_+	DUF1642 domain-containing protein	Q9MCL5	Streptococcus_virus	2.1e-19	56.5
WP_000958011.1\|186771_187020_+	hypothetical protein	NA	NA	NA	NA
WP_000667207.1\|187030_187426_+	hypothetical protein	K4JU53	Streptococcus_phage	9.1e-40	60.2
WP_000614972.1\|187422_187812_+	hypothetical protein	J7KJ21	Streptococcus_phage	5.1e-27	49.6
WP_000164677.1\|187981_188362_+	hypothetical protein	K4JTJ9	Streptococcus_phage	1.4e-24	44.7
WP_001103600.1\|188404_188605_+	hypothetical protein	A0A1P8VVP4	Streptococcus_phage	1.7e-18	84.2
WP_001042637.1\|188597_188843_+	hypothetical protein	NA	NA	NA	NA
WP_001038279.1\|188928_190008_+	DUF4417 domain-containing protein	A0A1S5S8J8	Streptococcus_phage	1.9e-143	68.9
WP_000509432.1\|189997_190408_+	hypothetical protein	K4K7P5	Streptococcus_phage	3.6e-47	70.1
WP_001136854.1\|190600_191044_+	hypothetical protein	A0A1C9LX59	Streptococcus_phage	1.2e-48	72.0
WP_001167688.1\|191030_192344_+\|terminase	PBSX family phage terminase large subunit	K4JW72	Streptococcus_phage	5.6e-219	82.8
WP_000052338.1\|192355_193939_+\|portal	phage portal protein	M1IFC5	Streptococcus_phage	2.8e-233	77.3
WP_000140092.1\|194037_195207_+\|capsid	phage minor capsid protein	A0A1P8VVK3	Streptococcus_phage	5.7e-138	64.7
WP_000011256.1\|195342_195921_+	phage scaffolding protein	A0A1C9LX53	Streptococcus_phage	1.4e-41	49.2
WP_000224752.1\|195943_196828_+	hypothetical protein	A0A1S5S8N6	Streptococcus_phage	5.8e-111	70.9
WP_001269647.1\|196838_197096_+	hypothetical protein	A0A1P8VVQ1	Streptococcus_phage	1.2e-08	56.9
WP_000221832.1\|197137_197527_+	hypothetical protein	K4JXK7	Streptococcus_phage	3.1e-40	67.9
WP_000565942.1\|197516_197843_+	hypothetical protein	M1IEU8	Streptococcus_phage	3.4e-32	58.9
WP_000077535.1\|197842_198205_+	hypothetical protein	A0A1P8VVL8	Streptococcus_phage	6.4e-32	58.8
WP_001180646.1\|198205_198613_+\|capsid	minor capsid protein	A0A1P8VVK7	Streptococcus_phage	2.8e-52	76.5
WP_000251918.1\|198615_199071_+	hypothetical protein	A0A1P8VVM4	Streptococcus_phage	5.0e-58	73.0
WP_000069050.1\|199102_199501_+	hypothetical protein	M1IR95	Streptococcus_phage	5.8e-26	51.5
WP_000459714.1\|199503_200088_+	hypothetical protein	A0A1P8VVK8	Streptococcus_phage	4.8e-69	64.9
WP_000763172.1\|200106_203883_+	tape measure protein	A0A1P8VVL4	Streptococcus_phage	2.4e-190	64.7
WP_001293185.1\|203875_205324_+\|tail	phage tail family protein	A0A1S5SE21	Streptococcus_phage	3.3e-63	32.1
WP_001882115.1\|205323_208125_+\|tail	phage tail protein	J7KJ56	Streptococcus_phage	1.5e-91	48.4
WP_000536261.1\|208135_210148_+	hypothetical protein	J7KC14	Streptococcus_phage	1.0e-174	52.4
WP_000404431.1\|210161_210488_+	DUF1366 domain-containing protein	J7KDI9	Streptococcus_phage	1.3e-31	68.2
WP_000698337.1\|210462_210675_+	hypothetical protein	J7KDP6	Streptococcus_phage	2.1e-14	60.0
WP_000215499.1\|210687_210990_+	hypothetical protein	X2KT07	Streptococcus_phage	2.2e-25	59.6
WP_001001960.1\|210991_211327_+\|holin	phage holin	A0A1P8VVK6	Streptococcus_phage	4.7e-37	72.1
WP_000236381.1\|211328_212048_+	CHAP domain-containing protein	A0A1U9WRD0	Streptococcus_virus	1.6e-58	72.1

DBSCAN-SWA_3

399192 : 480737

107

Streptococcus_phage(72.13%)

portal,terminase,tRNA,integrase,holin,tail,transposase,capsid,head,protease

attL 399097:399156|attR 467693:469009

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
399097:399156	attL	NA	NA	NA	NA
WP_000564846.1\|399192_400326_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_000500161.1\|400467_400911_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_001865515.1\|400864_401425_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000708156.1\|401433_402741_+	LCP family protein	NA	NA	NA	NA
WP_000690175.1\|402804_403101_-	hypothetical protein	NA	NA	NA	NA
WP_000368097.1\|403097_403517_-	HIT family protein	NA	NA	NA	NA
WP_000773453.1\|403852_404356_+	hypothetical protein	NA	NA	NA	NA
WP_000368100.1\|404407_404593_-	hypothetical protein	NA	NA	NA	NA
WP_000912307.1\|404664_405390_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-25	30.7
WP_000732713.1\|405391_406426_+	ABC transporter permease	NA	NA	NA	NA
WP_000155919.1\|406483_407284_+	phosphotransferase family protein	NA	NA	NA	NA
WP_001266024.1\|407273_407909_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_000179394.1\|408098_409169_-\|integrase	site-specific integrase	A7J266	Streptococcus_phage	3.9e-133	65.7
WP_001047048.1\|409313_409856_-	PH domain-containing protein	A0A0F6N4L7	Staphylococcus_phage	1.5e-32	41.3
WP_088196747.1\|409880_410636_-	helix-turn-helix transcriptional regulator	J7KJ52	Streptococcus_phage	2.6e-83	84.0
WP_000871400.1\|410991_411150_+	hypothetical protein	NA	NA	NA	NA
WP_088196748.1\|411306_411882_+	hypothetical protein	NA	NA	NA	NA
WP_017648778.1\|412129_412300_+	hypothetical protein	NA	NA	NA	NA
WP_001008979.1\|412499_413141_-	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_000658998.1\|413235_413439_+	hypothetical protein	NA	NA	NA	NA
WP_088196749.1\|413422_413782_-	hypothetical protein	NA	NA	NA	NA
WP_017650012.1\|413854_414082_+	helix-turn-helix transcriptional regulator	A0A141E0Q1	Streptococcus_phage	8.4e-14	55.2
WP_088196750.1\|414092_415004_+	DUF3102 domain-containing protein	J7KDG2	Streptococcus_phage	7.3e-125	84.5
WP_088196751.1\|414996_415518_+	ORF6C domain-containing protein	J7KJY1	Streptococcus_phage	6.6e-70	85.0
WP_017643462.1\|415536_415686_+	hypothetical protein	J7KH12	Streptococcus_phage	2.0e-08	62.5
WP_000239012.1\|415674_415887_-	hypothetical protein	M1PRU3	Streptococcus_phage	1.3e-16	60.0
WP_025194682.1\|416003_416180_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_088196752.1\|416259_416538_+	DNA-binding protein	B3GVX8	Streptococcus_phage	4.6e-22	54.3
WP_017643461.1\|416540_416678_+	hypothetical protein	NA	NA	NA	NA
WP_017772008.1\|416715_417405_+	DnaD domain protein	L0P704	Lactobacillus_phage	3.4e-34	58.8
WP_000600243.1\|417391_418174_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	2.4e-132	88.8
WP_000431574.1\|418300_418576_+	hypothetical protein	J7KJY6	Streptococcus_phage	1.6e-19	61.5
WP_000229418.1\|418562_418817_+	hypothetical protein	J7KK18	Streptococcus_phage	4.3e-35	85.7
WP_001001351.1\|418819_418981_+	hypothetical protein	J7KDI4	Streptococcus_phage	5.2e-18	84.9
WP_001092695.1\|418982_419312_+	hypothetical protein	J7KGX3	Streptococcus_phage	4.9e-47	87.2
WP_001262695.1\|419314_420256_+	recombinase RecT	J7KDK3	Streptococcus_phage	5.9e-170	95.9
WP_088196753.1\|420252_421050_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	1.0e-130	84.9
WP_000239531.1\|421211_421409_+	hypothetical protein	J7KIX6	Streptococcus_phage	8.9e-28	98.5
WP_000143295.1\|421398_421875_+	RusA family crossover junction endodeoxyribonuclease	J7KBT1	Streptococcus_phage	5.6e-60	98.2
WP_000130166.1\|421864_422212_+	hypothetical protein	J7KK12	Streptococcus_phage	1.7e-58	95.7
WP_000763911.1\|422223_422520_+	DUF1599 domain-containing protein	J7KDH9	Streptococcus_phage	8.9e-48	98.0
WP_165694394.1\|422503_422662_+	hypothetical protein	J7KJ16	Streptococcus_phage	4.5e-22	98.1
WP_000614971.1\|422658_423072_+	hypothetical protein	Q938M1	Temperate_phage	2.6e-29	79.7
WP_000159371.1\|423068_423245_+	hypothetical protein	NA	NA	NA	NA
WP_088196754.1\|423228_423468_+	hypothetical protein	J7KK64	Streptococcus_phage	2.0e-13	93.0
WP_165694395.1\|423470_424232_+	DNA methyltransferase	A0A191KBM4	Streptococcus_virus	1.7e-106	73.8
WP_001041375.1\|424212_424440_+	hypothetical protein	A3F630	Streptococcus_phage	9.6e-26	76.0
WP_001019151.1\|424696_425206_+	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	7.2e-29	46.6
WP_000660740.1\|425202_425469_+	hypothetical protein	NA	NA	NA	NA
WP_000142566.1\|425857_426292_+	ArpU family phage encoded transcriptional regulator	J7KDQ1	Streptococcus_phage	1.1e-70	93.7
WP_000033707.1\|426941_427262_+	hypothetical protein	C3U2K8	Lactococcus_phage	3.1e-14	40.8
WP_000802599.1\|427324_427579_+	hypothetical protein	NA	NA	NA	NA
WP_088196756.1\|427575_427893_+	HNH endonuclease	A0A1S5SFB3	Streptococcus_phage	8.1e-31	59.6
WP_000343900.1\|428029_428386_+	hypothetical protein	A0A2H4JAH7	uncultured_Caudovirales_phage	3.0e-34	61.0
WP_088196757.1\|428382_430026_+\|terminase	terminase large subunit	A0A1S5SF58	Streptococcus_phage	2.4e-267	80.3
WP_000649300.1\|430036_430318_+	hypothetical protein	NA	NA	NA	NA
WP_000696092.1\|430426_431575_+\|portal	phage portal protein	A0A1S5SFG8	Streptococcus_phage	8.7e-107	53.0
WP_000192153.1\|431555_432275_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A1S5SFF8	Streptococcus_phage	7.4e-72	60.3
WP_000178056.1\|432297_433458_+\|capsid	phage major capsid protein	A0A1S5SFB4	Streptococcus_phage	7.9e-116	57.3
WP_000343312.1\|433461_433755_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JAA9	uncultured_Caudovirales_phage	9.5e-10	42.5
WP_000868405.1\|433726_433876_+	hypothetical protein	NA	NA	NA	NA
WP_000087630.1\|433868_434216_+	hypothetical protein	A3F648	Streptococcus_phage	3.7e-29	55.7
WP_032457488.1\|434240_434612_+	HK97 gp10 family phage protein	A3F649	Streptococcus_phage	3.4e-52	78.9
WP_000237791.1\|434604_434985_+	hypothetical protein	A3F650	Streptococcus_phage	1.8e-40	64.3
WP_001149163.1\|434999_435605_+	hypothetical protein	A3F651	Streptococcus_phage	1.2e-70	74.1
WP_001281299.1\|435615_435918_+	hypothetical protein	A3F652	Streptococcus_phage	7.5e-34	69.4
WP_001051904.1\|436144_440068_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	0.0e+00	65.0
WP_047201285.1\|440079_441588_+\|tail	phage tail family protein	J7KH53	Streptococcus_phage	1.5e-228	77.5
WP_166724125.1\|441578_445400_+\|tail	phage tail protein	J7KBT9	Streptococcus_phage	0.0e+00	92.8
WP_088196758.1\|445412_447404_+	hypothetical protein	J7KC14	Streptococcus_phage	0.0e+00	97.3
WP_000404431.1\|447417_447744_+	DUF1366 domain-containing protein	J7KDI9	Streptococcus_phage	1.3e-31	68.2
WP_000698337.1\|447718_447931_+	hypothetical protein	J7KDP6	Streptococcus_phage	2.1e-14	60.0
WP_000215499.1\|447943_448246_+	hypothetical protein	X2KT07	Streptococcus_phage	2.2e-25	59.6
WP_000611524.1\|448247_448502_+\|holin	phage holin	J7KDR1	Streptococcus_phage	1.6e-37	96.4
WP_088196759.1\|448627_449959_+	lysin	Q8HA43	Streptococcus_phage	9.0e-265	99.5
WP_001061853.1\|450094_450991_+	sensor histidine kinase	J7KDG8	Streptococcus_phage	1.8e-168	100.0
WP_000258211.1\|450984_451284_+	STAS-like domain-containing protein	J7KJ12	Streptococcus_phage	3.8e-46	100.0
WP_000059049.1\|451533_452193_+	hypothetical protein	NA	NA	NA	NA
WP_000787652.1\|452196_452640_+	hypothetical protein	A0A0K2SUH1	Clostridium_phage	2.2e-13	34.4
WP_041971671.1\|453211_453688_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_000380478.1\|453714_454875_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_001140526.1\|454896_455193_+	YlxR family protein	NA	NA	NA	NA
WP_001065560.1\|455185_455488_+	YlxQ-related RNA-binding protein	NA	NA	NA	NA
WP_000039156.1\|455507_458291_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.1e-20	23.1
WP_000715537.1\|458381_458750_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_000804614.1\|458833_459838_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000156042.1\|460001_460418_+	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_000013400.1\|460430_462665_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.3e-95	35.0
WP_000683375.1\|462705_462912_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_000020721.1\|463021_463636_+	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_000593336.1\|463650_464463_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000182605.1\|464575_467218_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	3.2e-56	28.5
WP_000262487.1\|467247_467688_+	CoA-binding protein	NA	NA	NA	NA
WP_000564846.1\|467788_468922_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_000377090.1\|469095_469575_+	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
467693:469009	attR	NA	NA	NA	NA
WP_000703866.1\|469727_471293_+	YSIRK signal domain/LPXTG anchor domain surface protein	NA	NA	NA	NA
WP_000192298.1\|471405_472092_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.8e-35	38.2
WP_000770240.1\|472093_473131_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	1.3e-13	24.6
WP_000185054.1\|473144_473885_-	DUF975 family protein	NA	NA	NA	NA
WP_000129510.1\|474071_475214_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	7.1e-85	43.1
WP_000983191.1\|475320_475632_+	hypothetical protein	NA	NA	NA	NA
WP_000469149.1\|475638_476178_+	biotin transporter BioY	NA	NA	NA	NA
WP_000779461.1\|476316_477093_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_001169006.1\|477092_477599_+	nucleoside deaminase	NA	NA	NA	NA
WP_000148892.1\|477870_479220_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_000412414.1\|479541_480069_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_000061940.1\|480059_480737_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

DBSCAN-SWA_4

508835 : 562871

Bacillus_phage(33.33%)

tRNA,integrase,transposase

attL 508781:508840|attR 561472:562902

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
508781:508840	attL	NA	NA	NA	NA
WP_166724132.1\|508835_510180_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.2e-64	50.4
WP_000948275.1\|510239_510671_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_000955820.1\|510909_511194_-	DUF2316 family protein	NA	NA	NA	NA
WP_000660666.1\|511280_511598_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_001158467.1\|511621_512017_-	cupin domain-containing protein	NA	NA	NA	NA
WP_000547676.1\|512026_512416_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_000861550.1\|512431_513469_-	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_000132685.1\|513578_514433_-	aldo/keto reductase	A0A1V0SKP9	Klosneuvirus	4.3e-34	33.7
WP_029662111.1\|514517_515369_-	cation transporter	NA	NA	NA	NA
WP_088181596.1\|515383_516188_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_000237802.1\|516373_516898_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000564876.1\|517092_518286_-	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
WP_000489917.1\|518533_520096_+	alpha-like surface protein	NA	NA	NA	NA
WP_000108709.1\|520807_521101_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_001279890.1\|521097_521286_+	hypothetical protein	NA	NA	NA	NA
WP_000727985.1\|521438_521810_+	lipoprotein	NA	NA	NA	NA
WP_071659957.1\|522290_522761_+\|integrase	tyrosine-type recombinase/integrase	A7J266	Streptococcus_phage	2.0e-09	30.6
WP_000119699.1\|524182_524437_+	DUF1912 family protein	NA	NA	NA	NA
WP_001119098.1\|524545_524857_+	hypothetical protein	NA	NA	NA	NA
WP_001166195.1\|525124_525694_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000590589.1\|525791_526376_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001021308.1\|526372_526939_+	AAA family ATPase	NA	NA	NA	NA
WP_000032207.1\|526938_529590_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	9.2e-152	41.5
WP_088196760.1\|529760_530720_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_000492960.1\|530880_531744_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_000191691.1\|531790_532966_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_000021302.1\|533271_534336_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_000748011.1\|534449_535442_+	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	1.1e-54	40.1
WP_000592263.1\|535486_535936_-	thiol reductase thioredoxin	NA	NA	NA	NA
WP_001266829.1\|536065_536605_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_000384889.1\|536616_536907_+	hypothetical protein	NA	NA	NA	NA
WP_000161892.1\|536903_537389_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	7.3e-15	31.7
WP_000796095.1\|537378_538452_+	PDZ domain-containing protein	NA	NA	NA	NA
WP_001224500.1\|539927_540506_+	DUF1027 domain-containing protein	NA	NA	NA	NA
WP_001124990.1\|540556_541663_+	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_000919802.1\|541662_542178_+	VanZ family protein	NA	NA	NA	NA
WP_000022475.1\|542356_544102_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	5.6e-49	27.9
WP_000841525.1\|544091_545831_+	ABC transporter ATP-binding protein	F2Y1V6	Organic_Lake_phycodnavirus	9.4e-20	26.9
WP_000925635.1\|545958_546525_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	2.9e-31	40.9
WP_166724132.1\|546633_547978_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.2e-64	50.4
WP_000857895.1\|548024_548564_-	biotin transporter BioY	NA	NA	NA	NA
WP_000009961.1\|548564_549557_-	biotin synthase BioB	NA	NA	NA	NA
WP_000796107.1\|550184_551300_+	thiolase family protein	NA	NA	NA	NA
WP_000894048.1\|551292_552522_+	AMP-binding protein	NA	NA	NA	NA
WP_000949176.1\|552634_553267_+	endonuclease III	NA	NA	NA	NA
WP_000587310.1\|553267_553663_-	prepilin peptidase	NA	NA	NA	NA
WP_000865866.1\|553817_554027_+	YqgQ family protein	NA	NA	NA	NA
WP_000038547.1\|554023_554992_+	ROK family glucokinase	NA	NA	NA	NA
WP_000367664.1\|555003_555384_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_000183432.1\|555615_557457_+	translational GTPase TypA	A0A1B0RXH7	Streptococcus_phage	7.1e-18	44.3
WP_000499533.1\|557501_557747_+	DUF3165 family protein	NA	NA	NA	NA
WP_000849681.1\|557876_559232_+	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_000516700.1\|559234_560311_+	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	NA	NA	NA	NA
WP_001124859.1\|560314_561451_+	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_166724132.1\|561526_562871_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.2e-64	50.4
561472:562902	attR	NA	NA	NA	NA

DBSCAN-SWA_5

573155 : 634548

Streptococcus_phage(36.36%)

protease,tRNA,integrase,transposase

attL 569446:569461|attR 641452:641467

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
569446:569461	attL	NA	NA	NA	NA
WP_000882549.1\|573155_575417_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	7.4e-126	39.4
WP_000443582.1\|575714_575945_+	DUF1797 family protein	NA	NA	NA	NA
WP_001011647.1\|576086_576779_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000230134.1\|576771_577506_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-35	41.8
WP_001106845.1\|577792_579487_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	5.5e-126	42.6
WP_000137498.1\|579625_580480_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	1.5e-39	40.2
WP_000634981.1\|580476_581313_+	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_001286939.1\|581438_582779_+	exodeoxyribonuclease VII large subunit	L7RDW5	Acanthamoeba_polyphaga_moumouvirus	3.4e-38	31.7
WP_001280900.1\|582756_582972_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_000256279.1\|582971_583844_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_001041040.1\|583836_584664_+	TlyA family rRNA (cytidine-2'-O)-methyltransferase	NA	NA	NA	NA
WP_000747940.1\|584650_585124_+	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_000923619.1\|585135_586794_+	DNA repair protein RecN	NA	NA	NA	NA
WP_000034838.1\|586906_587743_+	DegV family protein	NA	NA	NA	NA
WP_001035227.1\|587735_588575_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_000806954.1\|588549_589152_+	YpmS family protein	NA	NA	NA	NA
WP_001284634.1\|589254_589530_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	1.2e-25	71.9
WP_001290370.1\|589726_589924_+	hypothetical protein	NA	NA	NA	NA
WP_000254063.1\|589967_590900_-	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	6.7e-65	43.7
WP_001185391.1\|591086_592322_-	aminoacyltransferase	NA	NA	NA	NA
WP_000285514.1\|592340_593552_-	aminoacyltransferase	NA	NA	NA	NA
WP_000527090.1\|593564_594800_-	aminoacyltransferase	NA	NA	NA	NA
WP_000200668.1\|594784_595597_-	sugar-phosphatase	NA	NA	NA	NA
WP_001003543.1\|595667_596984_-	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	8.1e-24	29.6
WP_001209458.1\|597047_597446_+	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_000910747.1\|597789_600474_+	calcium-translocating P-type ATPase, PMCA-type	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	2.8e-71	29.5
WP_000163483.1\|600518_601379_-	metallophosphoesterase	NA	NA	NA	NA
WP_000064640.1\|601530_603462_+	fructose-1,6-bisphosphatase	NA	NA	NA	NA
WP_000351637.1\|603551_604676_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_011324939.1\|604744_605842_+	peptide chain release factor 2	NA	NA	NA	NA
WP_001173889.1\|605861_606554_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	1.3e-28	35.1
WP_000236202.1\|606537_607467_+	ABC transporter permease	NA	NA	NA	NA
WP_166724132.1\|607514_608860_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.2e-64	50.4
WP_001022571.1\|608952_609663_-	thioesterase	NA	NA	NA	NA
WP_001115859.1\|609659_610358_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.5e-82	64.9
WP_000048144.1\|610525_611290_+	(S)-acetoin forming diacetyl reductase	V5L4T3	Hirudovirus	9.8e-06	31.8
WP_000458614.1\|611397_613905_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	2.0e-217	50.3
WP_000221826.1\|613990_615184_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000038470.1\|615204_616551_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.3e-56	31.4
WP_166724132.1\|616622_617967_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.2e-64	50.4
WP_000167491.1\|618024_618582_-	ECF transporter S component	NA	NA	NA	NA
WP_001031097.1\|618578_619562_-	nucleoside hydrolase	NA	NA	NA	NA
WP_000965180.1\|619807_620221_-	OsmC family protein	NA	NA	NA	NA
WP_001278848.1\|620374_621265_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	5.7e-05	28.1
WP_001231102.1\|621261_622236_+	YvcK family protein	A1IMD5	Streptococcus_phage	9.8e-144	78.8
WP_000011316.1\|622232_623144_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.4e-107	65.7
WP_000752457.1\|623158_624556_+	C69 family dipeptidase	NA	NA	NA	NA
WP_001227406.1\|624697_626218_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_000710757.1\|626330_626591_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_000583238.1\|626699_627635_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_000189639.1\|627900_628923_+	adenosine deaminase	NA	NA	NA	NA
WP_001162136.1\|628981_629425_+	flavodoxin	NA	NA	NA	NA
WP_000418127.1\|629501_629777_+	chorismate mutase	NA	NA	NA	NA
WP_000595711.1\|629769_630966_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	7.9e-103	54.2
WP_088181596.1\|631418_632223_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_001068667.1\|632406_632754_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_071659971.1\|632898_633513_-\|integrase	site-specific integrase	F8HGP4	Streptococcus_phage	9.2e-55	60.7
WP_001872365.1\|633515_633782_-	hypothetical protein	Q77YW7	Streptococcus_phage	9.2e-20	65.2
WP_000640620.1\|633781_634186_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001122304.1\|634347_634548_+\|transposase	IS3 family transposase	NA	NA	NA	NA
641452:641467	attR	NA	NA	NA	NA

DBSCAN-SWA_6

694006 : 786679

Streptococcus_phage(78.43%)

portal,terminase,holin,tail,capsid,transposase,head,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000743701.1\|694006_694861_+	ParB/RepB/Spo0J family partition protein	S5VSZ7	Leptospira_phage	9.9e-07	30.2
WP_000659121.1\|694937_695168_+	hypothetical protein	A0A223LEC3	Bacillus_phage	4.2e-13	48.5
WP_000503424.1\|695238_695430_+	hypothetical protein	NA	NA	NA	NA
WP_000635249.1\|696675_696915_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	6.8e-22	81.5
WP_001814874.1\|696963_697047_+	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_088196767.1\|697171_697909_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.1e-134	99.2
WP_166724132.1\|698410_699755_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.2e-64	50.4
WP_002326827.1\|699867_700764_+	ParA family protein	A0A1X9I765	Streptococcus_phage	1.1e-152	97.9
WP_000527318.1\|700861_701071_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	1.4e-31	98.6
WP_002326825.1\|701088_701361_+	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.4e-07	96.7
WP_002943355.1\|701362_701632_+	zeta toxin family protein	NA	NA	NA	NA
WP_050197324.1\|703073_703373_+	hypothetical protein	NA	NA	NA	NA
WP_050197323.1\|703386_703677_+	hypothetical protein	NA	NA	NA	NA
WP_050197322.1\|703772_704411_+	hypothetical protein	NA	NA	NA	NA
WP_050197321.1\|704450_705551_+	toprim domain-containing protein	NA	NA	NA	NA
WP_000110922.1\|705578_705806_+	hypothetical protein	NA	NA	NA	NA
WP_000048066.1\|705802_706192_+	hypothetical protein	NA	NA	NA	NA
WP_000667951.1\|706242_706533_+	hypothetical protein	NA	NA	NA	NA
WP_000578719.1\|706602_707079_+	helix-turn-helix transcriptional regulator	X2CXD8	Lactobacillus_phage	3.6e-06	34.8
WP_001235242.1\|707078_707846_+	zeta toxin family protein	NA	NA	NA	NA
WP_001213955.1\|707882_710390_+	AAA family ATPase	A0A1B1IUG5	uncultured_Mediterranean_phage	1.7e-09	44.2
WP_000140674.1\|710727_711090_+	hypothetical protein	NA	NA	NA	NA
WP_000431640.1\|711092_711458_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_000261812.1\|711444_713328_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_000719507.1\|713424_714798_+	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	5.2e-58	35.3
WP_000276751.1\|714838_715537_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-24	32.8
WP_000977993.1\|715514_716858_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_000452012.1\|717047_717749_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.7e-49	43.6
WP_000181737.1\|717741_718479_+	lantibiotic ABC transporter permease	NA	NA	NA	NA
WP_001033677.1\|718456_719143_+	hypothetical protein	NA	NA	NA	NA
WP_001058290.1\|719490_719658_+	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000400477.1\|719898_722874_+	lantibiotic dehydratase	NA	NA	NA	NA
WP_000536729.1\|722854_724663_+	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	4.7e-14	26.1
WP_000344171.1\|724655_725933_+	lanthionine synthetase C family protein	NA	NA	NA	NA
WP_001226539.1\|725934_726651_+	NisI/SpaI family lantibiotic immunity lipoprotein	NA	NA	NA	NA
WP_000878635.1\|726918_727323_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_088196768.1\|727827_729633_+	recombinase family protein	A0A2I4R675	Erysipelothrix_phage	3.7e-152	52.7
WP_017649105.1\|731136_731667_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_151897943.1\|731836_738313_+	YPDG domain-containing protein	NA	NA	NA	NA
WP_000459851.1\|739172_741041_+	ImmA/IrrE family metallo-endopeptidase	E4ZFJ9	Streptococcus_phage	3.6e-304	81.2
WP_001122248.1\|741449_742019_+	hypothetical protein	A0A1B0RXB3	Streptococcus_phage	2.5e-86	81.0
WP_000905643.1\|742057_744013_-	DNA polymerase	D0R0B0	Streptococcus_phage	0.0e+00	84.3
WP_000464240.1\|744062_744227_-	hypothetical protein	NA	NA	NA	NA
WP_000208945.1\|744243_744807_-	DUF2815 family protein	A0A1B0RXA9	Streptococcus_phage	1.9e-91	93.9
WP_001914156.1\|744811_745933_-	DUF2800 domain-containing protein	A0A1X9I6D8	Streptococcus_phage	8.0e-198	88.2
WP_000041407.1\|745925_746249_-	hypothetical protein	A0A1B0RXB7	Streptococcus_phage	2.0e-32	71.2
WP_001160921.1\|746645_748928_+	hypothetical protein	A0A1B0RXC5	Streptococcus_phage	0.0e+00	79.6
WP_001208492.1\|749211_749493_+	VRR-NUC domain-containing protein	M1PFY8	Streptococcus_phage	7.9e-38	79.6
WP_000768925.1\|749473_750850_+	DEAD/DEAH box helicase	A0A1X9I6B0	Streptococcus_phage	1.8e-231	86.2
WP_000361944.1\|750842_751340_+	hypothetical protein	A0A1B0RXB9	Streptococcus_phage	1.7e-62	74.4
WP_000640706.1\|751732_752770_+	methionine adenosyltransferase	E4ZFL0	Streptococcus_phage	1.9e-169	84.6
WP_001138031.1\|752771_753137_+	HNH endonuclease	A0A1B0RXJ3	Streptococcus_phage	6.6e-61	86.0
WP_000999417.1\|753425_753881_+	hypothetical protein	M1Q209	Streptococcus_phage	2.1e-43	51.0
WP_000211624.1\|753852_755109_+	DNA modification methylase	A0A1B0RXJ0	Streptococcus_phage	1.8e-222	88.7
WP_000164558.1\|756420_756675_+	hypothetical protein	NA	NA	NA	NA
WP_000999360.1\|756685_757135_+	DUF4314 domain-containing protein	A0A1X9I6A3	Streptococcus_phage	6.1e-16	62.1
WP_000290865.1\|757186_757660_+\|terminase	phage terminase small subunit P27 family	A0A1X9I6K0	Streptococcus_phage	2.3e-85	97.5
WP_000220984.1\|757656_759249_+\|terminase	terminase large subunit	A0A1X9I6B3	Streptococcus_phage	2.8e-305	95.1
WP_001166641.1\|759319_759577_+	type II toxin-antitoxin system Phd/YefM family antitoxin	E4ZFM1	Streptococcus_phage	1.2e-35	95.3
WP_001221830.1\|759573_759945_+	type II toxin-antitoxin system death-on-curing family toxin	A0A1X9I6C0	Streptococcus_phage	1.2e-57	89.4
WP_000149738.1\|759970_760297_+	hypothetical protein	NA	NA	NA	NA
WP_000523693.1\|760364_761654_+\|portal	phage portal protein	A0A1B0RXD8	Streptococcus_phage	2.2e-228	90.6
WP_001225240.1\|761646_762345_+\|protease	Clp protease ClpP	A0A1B0RXE1	Streptococcus_phage	1.0e-105	83.2
WP_000040493.1\|762358_763567_+\|capsid	phage major capsid protein	E4ZFM5	Streptococcus_phage	1.8e-211	91.0
WP_000987322.1\|763563_763821_+\|head,tail	phage gp6-like head-tail connector protein	D0R0D7	Streptococcus_phage	1.5e-27	74.1
WP_000705390.1\|763820_764159_+\|head,tail	head-tail adaptor protein	A0A1B0RXJ6	Streptococcus_phage	6.2e-37	66.1
WP_000161243.1\|764151_764520_+	HK97 gp10 family phage protein	Q6DMT7	Streptococcus_phage	1.1e-34	63.8
WP_001209973.1\|764528_764855_+	hypothetical protein	M1Q1Z4	Streptococcus_phage	1.6e-37	67.6
WP_000818566.1\|764857_765427_+\|tail	phage tail protein	E4ZFM9	Streptococcus_phage	1.6e-98	95.7
WP_001249615.1\|765438_765858_+	hypothetical protein	E4ZFN0	Streptococcus_phage	1.3e-55	74.8
WP_000918336.1\|766152_769272_+\|tail	phage tail tape measure protein	Q6DMT2	Streptococcus_phage	5.1e-242	75.5
WP_000589858.1\|769268_769994_+	hypothetical protein	Q6DMT1	Streptococcus_phage	8.0e-82	57.9
WP_000966166.1\|769993_772909_+\|tail	phage tail protein	Q6DMT0	Streptococcus_phage	0.0e+00	65.2
WP_000796402.1\|772921_774778_+	hypothetical protein	Q6DMS9	Streptococcus_phage	1.5e-257	73.4
WP_000661350.1\|774795_775194_+\|holin	phage holin family protein	D0R0E9	Streptococcus_phage	5.1e-38	60.8
WP_000123549.1\|776737_776845_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_000290966.1\|777152_778394_+	recombinase family protein	A0A1X9I6J1	Streptococcus_phage	1.9e-171	70.0
WP_172396919.1\|778296_779643_+	recombinase family protein	E4ZFN9	Streptococcus_phage	1.9e-201	79.1
WP_000132373.1\|779725_780796_+	hypothetical protein	NA	NA	NA	NA
WP_000672531.1\|780817_782116_+	hypothetical protein	NA	NA	NA	NA
WP_001142755.1\|782333_782555_+	hypothetical protein	NA	NA	NA	NA
WP_000757296.1\|782672_783410_+	acid phosphatase AphA	NA	NA	NA	NA
WP_001267084.1\|783730_784249_+	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
WP_000944931.1\|785085_785415_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_088187511.1\|785534_786679_-\|transposase	IS3-like element ISSag5 family transposase	Q8W6R2	Burkholderia_virus	2.4e-16	26.1

DBSCAN-SWA_7

1303541 : 1366584

Indivirus(12.5%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001259491.1\|1303541_1304252_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_000863788.1\|1304341_1305130_-	esterase family protein	NA	NA	NA	NA
WP_001280077.1\|1305186_1306848_-	ribonuclease J	NA	NA	NA	NA
WP_000564846.1\|1307203_1308337_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_000245079.1\|1308471_1309233_-	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	4.1e-12	29.3
WP_000587303.1\|1309232_1310096_-	ABC transporter permease	NA	NA	NA	NA
WP_000790858.1\|1310108_1311113_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000006719.1\|1311470_1313126_+	fibronectin/fibrinogen-binding protein	A0A1J0F9J4	Only_Syngen_Nebraska_virus	2.3e-07	41.0
WP_000005484.1\|1313179_1313899_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_000140348.1\|1313912_1315595_-	acetolactate synthase AlsS	NA	NA	NA	NA
WP_000934876.1\|1315704_1316931_-	hypothetical protein	NA	NA	NA	NA
WP_001081539.1\|1316920_1318111_-	AI-2E family transporter	NA	NA	NA	NA
WP_000796045.1\|1318202_1318664_-	NUDIX hydrolase	NA	NA	NA	NA
WP_000163516.1\|1318653_1319136_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_000564846.1\|1320711_1321845_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_000277598.1\|1323948_1324989_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	9.4e-68	43.6
WP_000459888.1\|1325040_1325553_-	hypothetical protein	NA	NA	NA	NA
WP_000139165.1\|1325552_1326146_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	NA	NA	NA	NA
WP_000676113.1\|1326145_1327015_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.5e-100	61.8
WP_000716841.1\|1327073_1328177_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_000647414.1\|1328185_1328974_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_000365677.1\|1328963_1329647_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000221657.1\|1329750_1330431_-	DnaD domain-containing protein	Q938N2	Temperate_phage	1.9e-08	31.8
WP_000365343.1\|1330548_1331067_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.6e-31	44.1
WP_000564797.1\|1331248_1332382_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_001247524.1\|1332515_1335080_-	GBS Bsp-like repeat-containing protein	NA	NA	NA	NA
WP_000622242.1\|1335231_1337430_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-72	28.9
WP_000124584.1\|1337426_1338188_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000405387.1\|1338189_1339119_-	ribonuclease Z	NA	NA	NA	NA
WP_000568323.1\|1339160_1339808_-	cystathionine beta-lyase	NA	NA	NA	NA
WP_000573350.1\|1339800_1341039_-	GTPase HflX	NA	NA	NA	NA
WP_001226482.1\|1341129_1342020_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_000239229.1\|1342130_1342307_+	DUF3042 family protein	NA	NA	NA	NA
WP_000823015.1\|1343400_1347159_-	pullulanase	NA	NA	NA	NA
WP_000130593.1\|1348075_1348660_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_000150956.1\|1348756_1350163_-	dipeptidase PepV	NA	NA	NA	NA
WP_000670191.1\|1350209_1350812_-	nitroreductase family protein	NA	NA	NA	NA
WP_001003961.1\|1352804_1354586_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_000567584.1\|1354744_1355512_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_000285038.1\|1355570_1356911_-	MATE family efflux transporter	NA	NA	NA	NA
WP_000245056.1\|1357010_1357427_-	VOC family protein	NA	NA	NA	NA
WP_000582587.1\|1357430_1357928_-	hypothetical protein	NA	NA	NA	NA
WP_088196774.1\|1358149_1358746_+	Ltp family lipoprotein	NA	NA	NA	NA
WP_088196775.1\|1358934_1360039_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.4e-69	49.3
WP_000754576.1\|1361868_1364340_-	pneumococcal-type histidine triad protein	NA	NA	NA	NA
WP_000715197.1\|1364352_1365273_-	metal ABC transporter substrate-binding lipoprotein/laminin-binding adhesin Lmb	NA	NA	NA	NA
WP_000564846.1\|1365450_1366584_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

1600093 : 1657373

Streptococcus_phage(47.62%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000160532.1\|1600093_1601260_+\|transposase	IS30-like element ISSag9 family transposase	NA	NA	NA	NA
WP_000958259.1\|1601593_1602976_-	MFS transporter	NA	NA	NA	NA
WP_001262295.1\|1602983_1604198_-	amidohydrolase	NA	NA	NA	NA
WP_000795892.1\|1604455_1605361_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	7.3e-24	27.9
WP_000639447.1\|1605421_1605775_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_162837466.1\|1605845_1607190_+\|transposase	IS3-like element IS861 family transposase	A0A1B1P773	Bacillus_phage	3.7e-64	50.0
WP_000546859.1\|1607239_1608955_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	3.7e-37	30.8
WP_000231579.1\|1609036_1611487_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	8.7e-88	51.4
WP_000721136.1\|1611652_1612456_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	38.4
WP_000494347.1\|1612507_1613341_-	metal ABC transporter permease	NA	NA	NA	NA
WP_000587174.1\|1613342_1614059_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	5.6e-19	32.5
WP_000759089.1\|1614229_1615156_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000188485.1\|1615322_1615970_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_000689757.1\|1616009_1616699_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_000517852.1\|1616708_1616978_-	hypothetical protein	NA	NA	NA	NA
WP_000344991.1\|1616977_1617532_-	NUDIX hydrolase	NA	NA	NA	NA
WP_000073770.1\|1617552_1618932_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	2.6e-33	37.2
WP_000564846.1\|1619100_1620234_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_000237569.1\|1620501_1620915_-	VOC family protein	NA	NA	NA	NA
WP_000625774.1\|1620927_1621305_-	VOC family protein	NA	NA	NA	NA
WP_000762189.1\|1621393_1622350_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_000170241.1\|1623036_1623735_-	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_000141918.1\|1623727_1623964_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_000411787.1\|1624053_1624302_-\|tRNA	aminoacyl-tRNA synthetase	NA	NA	NA	NA
WP_000752176.1\|1624499_1625000_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000274807.1\|1625239_1626508_-	glycosyltransferase	NA	NA	NA	NA
WP_088181596.1\|1626515_1627320_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_001173115.1\|1627309_1627513_-	hypothetical protein	NA	NA	NA	NA
WP_088196780.1\|1627652_1629812_-	hypothetical protein	NA	NA	NA	NA
WP_000533132.1\|1629818_1631264_-	CotH kinase family protein	NA	NA	NA	NA
WP_000654037.1\|1631256_1631934_-	DUF4956 domain-containing protein	NA	NA	NA	NA
WP_001006715.1\|1631985_1632681_-	polyphosphate polymerase domain-containing protein	NA	NA	NA	NA
WP_000239244.1\|1633046_1634384_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_000136757.1\|1634579_1636577_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	1.3e-97	39.6
WP_000248364.1\|1636719_1637595_+	SAM-dependent methyltransferase TehB	NA	NA	NA	NA
WP_000039372.1\|1637752_1638448_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_000556335.1\|1638783_1640001_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_000735436.1\|1639984_1640827_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000767484.1\|1640903_1641731_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	4.3e-124	78.0
WP_000287944.1\|1641770_1642127_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.5e-41	71.8
WP_000966773.1\|1642128_1642605_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.0e-37	50.3
WP_000232156.1\|1642659_1643841_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	7.0e-168	75.6
WP_001167085.1\|1643903_1644452_-	acetyltransferase	M1PSC3	Streptococcus_phage	1.1e-54	58.4
WP_000603277.1\|1645744_1646380_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_000425856.1\|1646649_1647519_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	4.9e-110	70.4
WP_000358198.1\|1647518_1647845_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
WP_000364565.1\|1647874_1648738_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	7.3e-74	49.7
WP_000715592.1\|1648757_1649393_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
WP_000160532.1\|1649601_1650768_+\|transposase	IS30-like element ISSag9 family transposase	NA	NA	NA	NA
WP_001144248.1\|1651032_1651692_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	5.2e-64	55.6
WP_000178146.1\|1651710_1652421_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-18	28.5
WP_001185981.1\|1652420_1653185_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.4e-14	24.3
WP_000662323.1\|1653185_1654139_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_000941400.1\|1654141_1655011_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_000415515.1\|1655116_1656283_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001041186.1\|1656437_1656683_-	DUF2129 domain-containing protein	NA	NA	NA	NA
WP_000613483.1\|1656782_1657373_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	3.7e-53	54.6

DBSCAN-SWA_9

1994677 : 2041514

Streptococcus_phage(26.67%)

holin,integrase,transposase

attL 1994940:1994954|attR 2015594:2015608

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000257255.1\|1994677_1995799_-\|integrase	site-specific integrase	A0A0M5M609	Bacillus_phage	3.9e-27	29.4
1994940:1994954	attL	NA	NA	NA	NA
WP_001188031.1\|1995848_1996175_-	DUF771 domain-containing protein	A0A1W6JPI1	Staphylococcus_phage	3.2e-06	30.5
WP_000578743.1\|1996367_1997000_-	hypothetical protein	NA	NA	NA	NA
WP_000048867.1\|1997080_1997872_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_000829082.1\|1997888_1998437_-	hypothetical protein	NA	NA	NA	NA
WP_000511832.1\|1998436_1999810_-	CHAP domain-containing protein	NA	NA	NA	NA
WP_000528441.1\|1999972_2000116_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_000357668.1\|2000305_2002306_-	hypothetical protein	NA	NA	NA	NA
WP_001279020.1\|2002321_2004592_-	ATP-binding protein	NA	NA	NA	NA
WP_088181596.1\|2004638_2005444_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_000390747.1\|2005704_2006115_-	conjugal transfer protein	NA	NA	NA	NA
WP_001055037.1\|2006125_2006392_-	hypothetical protein	NA	NA	NA	NA
WP_000565540.1\|2006412_2007366_-	conjugal transfer protein	NA	NA	NA	NA
WP_000481712.1\|2007418_2007673_-	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_000387490.1\|2007665_2007932_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_000560386.1\|2008076_2008550_-	hypothetical protein	NA	NA	NA	NA
WP_000383283.1\|2008557_2009040_-	antirestriction protein ArdA	NA	NA	NA	NA
WP_000017154.1\|2009092_2009365_-	hypothetical protein	NA	NA	NA	NA
WP_000010056.1\|2009499_2010069_-	hypothetical protein	NA	NA	NA	NA
WP_000491712.1\|2010071_2011421_-	AAA family ATPase	V9QJ85	Oenococcus_phage	1.0e-69	33.9
WP_000737133.1\|2011617_2011917_-	helix-turn-helix transcriptional regulator	G3MBD2	Bacillus_virus	3.6e-12	50.0
WP_000287183.1\|2011900_2012278_-	hypothetical protein	NA	NA	NA	NA
WP_000338839.1\|2012293_2013526_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.3e-28	28.6
WP_000047855.1\|2013759_2014899_-\|integrase	site-specific integrase	Q8SBN2	Clostridium_phage	6.1e-28	29.7
WP_000998327.1\|2014885_2015089_-	DUF3173 domain-containing protein	NA	NA	NA	NA
WP_000799121.1\|2015085_2016078_-	hypothetical protein	NA	NA	NA	NA
2015594:2015608	attR	NA	NA	NA	NA
WP_000204836.1\|2016303_2016486_-	hypothetical protein	NA	NA	NA	NA
WP_000910340.1\|2016733_2017036_+	helix-turn-helix transcriptional regulator	A0A139ZPK3	Marinitoga_camini_virus	1.9e-05	45.0
WP_047209535.1\|2017310_2018789_+	ABC-F type ribosomal protection protein Lsa(C)	Q6DMX7	Streptococcus_phage	2.2e-33	25.3
WP_000168528.1\|2018892_2019213_+	TfoX/Sxy family protein	NA	NA	NA	NA
WP_000113191.1\|2019605_2021324_-	cell division protein FtsK	A0A1S5SFB5	Streptococcus_phage	1.9e-41	31.6
WP_001062569.1\|2021343_2021805_-	hypothetical protein	NA	NA	NA	NA
WP_000808311.1\|2021826_2022123_-	hypothetical protein	NA	NA	NA	NA
WP_001281641.1\|2024667_2025921_-\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.4e-126	55.5
WP_001031939.1\|2026080_2027721_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	3.7e-50	29.8
WP_000640387.1\|2027749_2028142_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_001053209.1\|2028847_2030416_+	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_000901036.1\|2030983_2031706_-	ABC transporter permease	NA	NA	NA	NA
WP_000470461.1\|2031709_2032327_-	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_001867162.1\|2032384_2032495_-	epipeptide YydF family RiPP	NA	NA	NA	NA
WP_001204133.1\|2033013_2033868_-	aminoglycoside 6-adenylyltransferase	A0A1X9I6F2	Streptococcus_phage	2.2e-30	37.2
WP_001191784.1\|2034046_2034439_-	DUF2785 domain-containing protein	NA	NA	NA	NA
WP_000589231.1\|2034873_2035482_-	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_000827865.1\|2035468_2035804_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000403109.1\|2036325_2036814_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000838139.1\|2036982_2037744_-	ABC transporter permease	NA	NA	NA	NA
WP_000644459.1\|2037740_2038643_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.3e-29	33.8
WP_001090962.1\|2038639_2038846_-	PLDc N-terminal domain-containing protein	NA	NA	NA	NA
WP_000900244.1\|2038847_2039924_-	helix-turn-helix transcriptional regulator	A0A0A7AQV8	Bacillus_phage	6.9e-05	40.4
WP_162837466.1\|2040168_2041514_-\|transposase	IS3-like element IS861 family transposase	A0A1B1P773	Bacillus_phage	3.7e-64	50.0

DBSCAN-SWA_10

2158274 : 2165478

uncultured_Caudovirales_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001042655.1\|2158274_2158979_-	transglycosylase SLT domain-containing protein	A0A2H4J6C5	uncultured_Caudovirales_phage	4.2e-27	56.6
WP_000029068.1\|2159084_2159624_-	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	6.7e-17	45.8
WP_000359358.1\|2159839_2160634_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000510606.1\|2160626_2161469_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	2.0e-15	28.5
WP_000181757.1\|2161444_2162284_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	3.5e-20	30.0
WP_000976003.1\|2162283_2162826_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_000217754.1\|2162948_2164232_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	2.2e-05	23.6
WP_000706188.1\|2164233_2165478_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.7e-87	41.3

Anti-CRISPR protein detection

Acr_ID: NZ_CP021867.1|WP_088196751.1|414996_415518_+|ORF6C-domain-containing-protein

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Acr_ID: NZ_CP021867.1|WP_017643462.1|415536_415686_+|hypothetical-protein

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Acr_ID: NZ_CP021867.1|WP_000239012.1|415674_415887_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP021867.1|WP_088196751.1|414996_415518_+|ORF6C-domain-containing-protein

414996_415518_+

173 aa aa

399192-480737

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP021867_2	TypeII	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	414401-414372	2

1. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021867 position: 414401-414372, mismatch: 2

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaatctgttcttgcttttgctcgtc	Protospacer
************************ **.**

NZ_CP021867.1|WP_017643462.1|415536_415686_+|hypothetical-protein

415536_415686_+

49 aa aa

399192-480737

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP021867_2	TypeII	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	414401-414372	2

1. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021867 position: 414401-414372, mismatch: 2

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaatctgttcttgcttttgctcgtc	Protospacer
************************ **.**

NZ_CP021867.1|WP_000239012.1|415674_415887_-|hypothetical-protein

415674_415887_-

70 aa aa

399192-480737

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP021867_2	TypeII	2.1\|1064379\|30\|NZ_CP021867\|PILER-CR,CRISPRCasFinder,CRT	1064379-1064408	30	414401-414372	2

1. spacer 2.1|1064379|30|NZ_CP021867|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021867 position: 414401-414372, mismatch: 2

ccgttcaatctgttcttgcttttggtcatc	CRISPR spacer
ccgttcaatctgttcttgcttttgctcgtc	Protospacer
************************ **.**

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP021867

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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