CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021851	Enterobacter cloacae strain A1137 chromosome, complete genome	4 crisprs	csa3,PD-DExK,DEDDh,WYL,RT,DinG,cas3	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021851_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021851_1

1306609-1306713

Orphan

Consensus_repeat	Method
TGTCCAGCCGATGTCCAGCCAGTGTCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021851_1

>merge|NZ_CP021851|1|1306609-1306713|CRISPRCasFinder
AGTCAAATTTTTGTCCAGCCGATGTCCAGCCAGTGTCCAGCGCAAACGCAGTTATATCAATGCCTGCGGAGGCGGAGTGTCCAGCCGATGTCCAGCCAGTGTCCA

>NZ_CP021851|1|1|1306609-1306713|CRISPRCasFinder
AGTCAAATTTTTGTCCAGCCGATGTCCA	GCCAGTGTCCAGCGCAAACGCAGTTATATCAATGCCTGCGGAGGCGGAG
TGTCCAGCCGATGTCCAGCCAGTGTCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021851.1\|WP_025759380.1\|1308886_1309366_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021851.1\|WP_016042179.1\|1305201_1305429_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NZ_CP021851.1\|WP_032672628.1\|1312214_1312385_+\|NinE-family-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP021851.1\|WP_025760125.1\|1303314_1303512_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021851.1\|WP_025760126.1\|1302169_1302493_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021851.1\|WP_006809788.1\|1301808_1302018_-\|cell-division-protein-FtsZ	unknown	unknown	gnl\|CDD\|236900
NZ_CP021851.1\|WP_025759385.1\|1311209_1311641_+\|recombination-protein-NinB	unknown	unknown	gnl\|CDD\|182057
NZ_CP021851.1\|WP_025759389.1\|1312985_1313186_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226682
NZ_CP021851.1\|WP_016042178.1\|1304401_1305091_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP021851.1\|WP_025759375.1\|1305458_1306004_+\|toxin-YdaT-domain-containing-protein	unknown	unknown	gnl\|CDD\|368819
NZ_CP021851.1\|WP_071994071.1\|1309362_1309587_+\|Lar-family-restriction-alleviation-protein	unknown	unknown	gnl\|CDD\|379576
NZ_CP021851.1\|WP_025759382.1\|1309583_1310015_+\|ead/Ea22-like-family-protein	unknown	unknown	gnl\|CDD\|379401
NZ_CP021851.1\|WP_025760408.1\|1300763_1301738_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227278
NZ_CP021851.1\|WP_025759387.1\|1311633_1312215_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|377841
NZ_CP021851.1\|WP_025759388.1\|1312377_1312989_+\|recombination-protein-NinG	unknown	unknown	gnl\|CDD\|368603
NZ_CP021851.1\|WP_023294194.1\|1303805_1304168_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021851.1\|WP_025759378.1\|1307112_1308546_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672
NZ_CP021851.1\|WP_015571544.1\|1306087_1306234_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021851.1\|WP_025759383.1\|1310019_1310706_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021851.1\|WP_023330205.1\|1302014_1302173_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP021851.1\|WP_016042179.1\|1305201_1305429_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	4.9861e-23
NZ_CP021851.1\|WP_025759382.1\|1309583_1310015_+\|ead/Ea22-like-family-protein	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	1.45697e-13
NZ_CP021851.1\|WP_025759385.1\|1311209_1311641_+\|recombination-protein-NinB	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	4.25871e-63
NZ_CP021851.1\|WP_016042178.1\|1304401_1305091_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	5.10077e-29
NZ_CP021851.1\|WP_025759375.1\|1305458_1306004_+\|toxin-YdaT-domain-containing-protein	gnl\|CDD\|368819	pfam06254, YdaT_toxin, Putative bacterial toxin ydaT. YdaT_toxin is a family of putative bacterial toxins that are neutralized by the putative antitoxin YdaS, UniProtKB:P76063, family pfam144549.	1.61092e-36
NZ_CP021851.1\|WP_071994071.1\|1309362_1309587_+\|Lar-family-restriction-alleviation-protein	gnl\|CDD\|379576	pfam14354, Lar_restr_allev, Restriction alleviation protein Lar. This family includes the restriction alleviation protein Lar encoded by the Rac prophage of Escherichia coli. This protein modulates the activity of the Escherichia coli restriction and modification system.	2.37615e-05
NZ_CP021851.1\|WP_006809788.1\|1301808_1302018_-\|cell-division-protein-FtsZ	gnl\|CDD\|236900	PRK11354, kil, FtsZ inhibitor protein; Reviewed.	4.00543e-36
NZ_CP021851.1\|WP_025760408.1\|1300763_1301738_-\|hypothetical-protein	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	1.53662e-05
NZ_CP021851.1\|WP_032672628.1\|1312214_1312385_+\|NinE-family-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	1.14156e-22
NZ_CP021851.1\|WP_025759389.1\|1312985_1313186_+\|hypothetical-protein	gnl\|CDD\|226682	COG4229, COG4229, Predicted enolase-phosphatase [Energy production and conversion].	0.0058031
NZ_CP021851.1\|WP_025759388.1\|1312377_1312989_+\|recombination-protein-NinG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	3.82402e-62
NZ_CP021851.1\|WP_025759378.1\|1307112_1308546_+\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	0
NZ_CP021851.1\|WP_025759387.1\|1311633_1312215_+\|HNH-endonuclease	gnl\|CDD\|377841	pfam07463, NUMOD4, NUMOD4 motif. NUMOD4 is a putative DNA-binding motif found in homing endonucleases and related proteins.	3.75267e-09

>NZ_CP021851.1|WP_015571544.1|1306087_1306234_+|hypothetical-protein
MAKNPRYYHTAVHKNITRDRFIRSVNPIVAEKMRAILEELKRKESGRG
>NZ_CP021851.1|WP_025759375.1|1305458_1306004_+|toxin-YdaT-domain-containing-protein
MHSLAYQQGNKFSPTAMIYQNRREPESAALNIDGIREAVRAWAADCRSREFVAALIVEEWRSTGGTGLDIPTDSHRQMQKVFRWIDGGTEYAANNIRQLAPAIMAVLPLEYRHRLLPEDSFMSRLARLEKETSEAKVAVAMNAPRHQKLKELSEGIVEMFRVDPDLTAPLMAMVTSMLGVM
>NZ_CP021851.1|WP_016042179.1|1305201_1305429_+|helix-turn-helix-domain-containing-protein
MNKVIQRALEIVGSQKRLADICGVSQPAVHKWLNGGSVSPEKVTAIVNATGGEIKAHEIRPDLPDLFPHPENHAA
>NZ_CP021851.1|WP_016042178.1|1304401_1305091_-|helix-turn-helix-transcriptional-regulator
MKTFAERLNAAMSAADISQGQLADKVGISQPAIQKMTSGKTSGSRKMVELAHALGVRPEWLSSGVGEMRIDGNVPSAAQPVSETIDVFRVDVLDLKVSAGPGSFMISEFVEVLHAIEFTTEHARSLFGNRTQNDVKVMTVDGDSMCPTIQSGDRLFFDVSVRNFKVDGVYAFVFGQHFHVKRLQMQGLQLAVLSDNPAYKDWYVTEENQDQLYIMGKALIHESIAYNKL
>NZ_CP021851.1|WP_023294194.1|1303805_1304168_-|hypothetical-protein
MTQNVLPINQRLHDQAVDEFNRLHGTMIGEISAMLKTAKVAPLVDLRKKDPTFSNVVAELRMFRDVCCALAPHFLVDKTGEIADIDKLLTLANDLAQAIDADDPDALCAAIAALDVEPYI
>NZ_CP021851.1|WP_025760125.1|1303314_1303512_+|hypothetical-protein
MVLDEERISMKIQAMGRAVMELSLADLPMTQQNIIGKLEQYRKETGNVIGKGVNRDAAEIVRKGQ
>NZ_CP021851.1|WP_025760126.1|1302169_1302493_-|hypothetical-protein
MKKVSLSRHRYSLDWFTVDQVEVSLDTCWHYEMQFRLGCWYLMHRQYDKSQEKWLNRSELDFRLDDPADAVMKLGDRVYCFSKIHDENLSKEVSDLMKRVSARSEAS
>NZ_CP021851.1|WP_023330205.1|1302014_1302173_-|hypothetical-protein
MTVTHNGKQYTAKKLNDNEWQLTSVSAPREKLVLNRWQMHIAGLLEQVEVKV
>NZ_CP021851.1|WP_006809788.1|1301808_1302018_-|cell-division-protein-FtsZ
MINHYGTTPLIRQCVTPGMMAMHEGRTYRVSAVIQERKWVYLHTDAEIIRLSDCVIDVLLDGHGNPIQH
>NZ_CP021851.1|WP_025760408.1|1300763_1301738_-|hypothetical-protein
MSEVTDLVVIEKQNAMAVFTTKEQLDPIIEAIEKEARSLVPDVSTRKGRDAIASMAHKVARSKTYIDNAGKDLVAELKALPKQIDESRRIVRERLDALKDEVRKPLTDWENAELARKDALQQRLADLRSLADVIDGVGNYLPSVEIQQRIESAKAVSLDDSWQEVAAEAGVAKDSTIQQLESALIVAKQREHEAAELERLRKEAEEKARLEREENIRREAEEKARAELAERQRIEAEQRAELEKAAAVEAERLKAKQAEDARLAEEKRKADEQAKREADVKHRKTVGTNIVNALTSHTSLTREQAIEVLTALKDDLIPCAKIHY
>NZ_CP021851.1|WP_025759378.1|1307112_1308546_+|AAA-family-ATPase
MTSEILTVPHNVEAEQSVIGGLLLDDDNSERVQKVLAMLKPESFYSRPHQLIFAEMRQMFRDNKPVDGLTLFDALEGKGLAEQVGGFAYLAEIAKNTPSAANIVAYAASVREAAMERYGISRLTEATELLYSRNGMSATQKYEAIQGIFTQLADHSKTGSRRGLRSFGEVMDDWVADLEKRFDPSGEQRGMSTGIPSLDRLLAPKGLVKGSLFVIGARPKMGKTTLYGQMAINCAIREKKPALMFSLEMPSDQILEKLVGQKSGVNPSIFYMPATDDADDQYQGDYDGDFKKAIATAGRLSEIDMLYIDDTPGLSLAHIVSESRRIKREKGCVGMILVDYLTLMTAEKADRNDLAYGMITKGLKNLAKELGCVVVLLTQLNRELEKRVNKRPLPSDSRDTGQIEQDCDYWVGIHREGAFDDSVPPGETELILRLNRHGSTGTVYCNQINGAIYDTDQQAAAAERRGREQKPKKKGGF
>NZ_CP021851.1|WP_025759380.1|1308886_1309366_+|hypothetical-protein
MTNISAVKKMAELMQQMEENSPRVAALQYCLSEVAKRITDLEQKLAESQREFRAADATIENLQMKLEKLSSENAGLKDLARGWANATDDRLFEEHGEIFHDSIDACEEELKTICPATDAFLAEVRASSIEHAASERWGSGYVFDELNEFAAQLRKGVQS
>NZ_CP021851.1|WP_071994071.1|1309362_1309587_+|Lar-family-restriction-alleviation-protein
MSNLLPCPFCGGVAHVASEADHPEYGSGGRFYFVRCGSCRAQSGSKYAGPGNDCPIFYSEVRAEWNQRAEGAAQ
>NZ_CP021851.1|WP_025759382.1|1309583_1310015_+|ead/Ea22-like-family-protein
MSNIDKLALREAAEKATPGRIGDRIDGSGSIKYQCFGNDGSLVLQTDHKNMEYGFIGGNSEADELFFRMCDPATVLALLDELEAAEKRIAELEAREVVLPSVQDVHPLGPQSAKIFCEFHRSIVNRCADEIRKVGVKVSIKGN
>NZ_CP021851.1|WP_025759383.1|1310019_1310706_+|hypothetical-protein
MAEFTKEQLIKQAKKNIEVLRGAVEKIPGASDAAVIHLKLAEIALASLGAEPIGFAFADDVDLMRKKIKVGGMLTVRHQGEVALYTAPPAPVSVPDAMEMDDDFDSAFEHGKAVGWNAYRAAMLQGADVSLTHEGKNHHEDKLGMVHHLGDANEKGNSPVIPDGWVIVPVEPTEDMIVNGFESEPNESFSDERVWEAYDAMSGCQQAAHRAKLCWAAMISAARKLDVR
>NZ_CP021851.1|WP_025759385.1|1311209_1311641_+|recombination-protein-NinB
MSMNKDGIRLHKSNFSAIGQQIQPMLESGDCYRLIIKPWKDKRSLSQNALLWMWNGDVASAVNRHAESKLTEEDLHEFMKDMFCPAKPVTVLGETKMVKSTKLLDTEEMTFYLRRIEVWCAERGIKLRIPANSEYHEKGHDHV
>NZ_CP021851.1|WP_025759387.1|1311633_1312215_+|HNH-endonuclease
MFENEIWKPVPGYEDRFEVSSLARVRSLARKVTTCGRDKKTWTTRTIAGRILKGCTSSQYIRVSLSNKHEMLHRFVALAFVPNPNNYPHVNHIDGNKHNNLPENLEWCTHAMNMKHANETGLSNRNKTPVIAERDGFGYWFPSMQSTKKYGCNPALVHASINGRQGEHRGMQWSYCSETSRFEYQQLRDKQEA
>NZ_CP021851.1|WP_032672628.1|1312214_1312385_+|NinE-family-protein
MSTPLSRVITNEIFRVPARRQRKPAVKPSDIPTFKDYTARLVDQKWLRLAARRKHA
>NZ_CP021851.1|WP_025759388.1|1312377_1312989_+|recombination-protein-NinG
MRKPPRRKCKVCGEYFVPKFHDIRIRWCCPEHGAILAMEEREKEKVKAAAKRMKEQKEAEKAGRQRRAARRNELRPIRHWVQMTQRAFNDWRREMLLAAGYGCISCGTKSAFVWHAGHYRTTAAAPQLRFNPDNLWLQCPVCNVHKSGNIEAYRAALVELIGEERVLALESNNENHRYTREELDGIRAKARADLRVLKQREAA
>NZ_CP021851.1|WP_025759389.1|1312985_1313186_+|hypothetical-protein
MKAFTPVEARKFVASTWYETTQLSKRERLYAKARELISGDRAEIICQTDNPEYRKSAREWWNHDQS

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Crispr_ID: NZ_CP021851_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021851_2

2159229-2159337

Orphan

Consensus_repeat	Method
TACCAGCACAGGTCCGCATTTCTCCCTCTCCCTTTCAGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021851_2

>merge|NZ_CP021851|2|2159229-2159337|CRISPRCasFinder
TACCAGCACAGGTCCGCATTTCTCCCTCTCCCTTTCAGGGGTGAGGGGACTGGGCGGTGCGGTCTGTATTACCAGCACAGGTCCGCATTTCTCCCTCTCCCTTTCAGGG

>NZ_CP021851|2|2|2159229-2159337|CRISPRCasFinder
TACCAGCACAGGTCCGCATTTCTCCCTCTCCCTTTCAGGG	GTGAGGGGACTGGGCGGTGCGGTCTGTAT
TACCAGCACAGGTCCGCATTTCTCCCTCTCCCTTTCAGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021851.1\|WP_025757356.1\|2156116_2156935_+\|transcriptional-regulator-ChbR	unknown	unknown	gnl\|CDD\|182362
NZ_CP021851.1\|WP_008500676.1\|2153936_2154254_+\|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|182499
NZ_CP021851.1\|WP_025757347.1\|2165706_2166567_-\|fructosamine-kinase-family-protein	unknown	unknown	gnl\|CDD\|225547
NZ_CP021851.1\|WP_025757354.1\|2158411_2159161_+\|chitin-disaccharide-deacetylase	unknown	unknown	gnl\|CDD\|235007
NZ_CP021851.1\|WP_192869218.1\|2151268_2152159_-\|excinuclease-Cho	unknown	unknown	gnl\|CDD\|182535
NZ_CP021851.1\|WP_025757351.1\|2162102_2163494_-\|cystine/sulfocysteine:cation-symporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP021851.1\|WP_025757349.1\|2164313_2164985_-\|hexitol-phosphatase-HxpB	unknown	unknown	gnl\|CDD\|236770
NZ_CP021851.1\|WP_025757358.1\|2154333_2155692_+\|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|182363
NZ_CP021851.1\|WP_025757359.1\|2152261_2153089_-\|ammonia-dependent-NAD(+)-synthetase	unknown	unknown	gnl\|CDD\|234831
NZ_CP021851.1\|WP_025757361.1\|2150733_2151291_+\|environmental-stress-induced-protein-Ves	unknown	unknown	gnl\|CDD\|236905
NZ_CP021851.1\|WP_025757344.1\|2168297_2169056_+\|YdiY-family-protein	unknown	unknown	gnl\|CDD\|225679
NZ_CP021851.1\|WP_080276760.1\|2161757_2162054_+\|cell-division-activator-CedA	unknown	unknown	gnl\|CDD\|182246
NZ_CP021851.1\|WP_025757350.1\|2163621_2164212_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|183256
NZ_CP021851.1\|WP_003857836.1\|2153310_2153655_+\|osmotically-inducible-lipoprotein-OsmE	unknown	unknown	gnl\|CDD\|183058
NZ_CP021851.1\|WP_025757346.1\|2166672_2166963_-\|type-V-toxin-antitoxin-system-endoribonuclease-antitoxin-GhoS	unknown	unknown	gnl\|CDD\|371368
NZ_CP021851.1\|WP_025757357.1\|2155739_2156087_+\|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|182472
NZ_CP021851.1\|WP_025757345.1\|2167069_2168002_-\|6-phosphofructokinase-II	unknown	unknown	gnl\|CDD\|182361
NZ_CP021851.1\|WP_025757348.1\|2165133_2165670_+\|YniB-family-protein	unknown	unknown	gnl\|CDD\|372875
NZ_CP021851.1\|WP_025757355.1\|2157044_2158400_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|133432
NZ_CP021851.1\|WP_025757353.1\|2159361_2161611_-\|catalase-HPII	unknown	unknown	gnl\|CDD\|236886

Protein	Function_ID	Function_description	E-value
NZ_CP021851.1\|WP_025757356.1\|2156116_2156935_+\|transcriptional-regulator-ChbR	gnl\|CDD\|182362	PRK10296, PRK10296, DNA-binding transcriptional regulator ChbR; Provisional.	0
NZ_CP021851.1\|WP_008500676.1\|2153936_2154254_+\|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIB	gnl\|CDD\|182499	PRK10499, PRK10499, PTS sugar transporter subunit IIB.	1.05635e-65
NZ_CP021851.1\|WP_025757347.1\|2165706_2166567_-\|fructosamine-kinase-family-protein	gnl\|CDD\|225547	COG3001, COG3001, Uncharacterized protein conserved in bacteria [Function unknown].	1.61615e-168
NZ_CP021851.1\|WP_025757354.1\|2158411_2159161_+\|chitin-disaccharide-deacetylase	gnl\|CDD\|235007	PRK02134, PRK02134, chitin disaccharide deacetylase.	1.66615e-163
NZ_CP021851.1\|WP_192869218.1\|2151268_2152159_-\|excinuclease-Cho	gnl\|CDD\|182535	PRK10545, PRK10545, excinuclease Cho.	0
NZ_CP021851.1\|WP_025757351.1\|2162102_2163494_-\|cystine/sulfocysteine:cation-symporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP021851.1\|WP_025757349.1\|2164313_2164985_-\|hexitol-phosphatase-HxpB	gnl\|CDD\|236770	PRK10826, PRK10826, hexitol phosphatase HxpB.	4.02657e-153
NZ_CP021851.1\|WP_025757358.1\|2154333_2155692_+\|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIC	gnl\|CDD\|182363	PRK10297, PRK10297, PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional.	0
NZ_CP021851.1\|WP_025757359.1\|2152261_2153089_-\|ammonia-dependent-NAD(+)-synthetase	gnl\|CDD\|234831	PRK00768, nadE, ammonia-dependent NAD(+) synthetase.	0
NZ_CP021851.1\|WP_025757361.1\|2150733_2151291_+\|environmental-stress-induced-protein-Ves	gnl\|CDD\|236905	PRK11396, PRK11396, environmental stress-induced protein Ves.	3.94877e-138
NZ_CP021851.1\|WP_025757344.1\|2168297_2169056_+\|YdiY-family-protein	gnl\|CDD\|225679	COG3137, COG3137, Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane].	5.71194e-123
NZ_CP021851.1\|WP_080276760.1\|2161757_2162054_+\|cell-division-activator-CedA	gnl\|CDD\|182246	PRK10113, PRK10113, cell division activator CedA.	1.42407e-49
NZ_CP021851.1\|WP_025757350.1\|2163621_2164212_-\|metal-dependent-hydrolase	gnl\|CDD\|183256	PRK11648, PRK11648, metal-dependent hydrolase.	2.30868e-137
NZ_CP021851.1\|WP_003857836.1\|2153310_2153655_+\|osmotically-inducible-lipoprotein-OsmE	gnl\|CDD\|183058	PRK11251, PRK11251, osmotically-inducible lipoprotein OsmE.	1.25848e-65
NZ_CP021851.1\|WP_025757346.1\|2166672_2166963_-\|type-V-toxin-antitoxin-system-endoribonuclease-antitoxin-GhoS	gnl\|CDD\|371368	pfam11080, GhoS, Endoribonuclease GhoS. GhoS is part of the GhoT-GhoS type V toxin-antitoxin (TA) system. GhoT is inhibited by antitoxin GhoS, which specifically cleaves its mRNA.	1.74251e-30
NZ_CP021851.1\|WP_025757357.1\|2155739_2156087_+\|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIA	gnl\|CDD\|182472	PRK10454, PRK10454, PTS N,N'-diacetylchitobiose transporter subunit IIA.	2.05881e-62
NZ_CP021851.1\|WP_025757345.1\|2167069_2168002_-\|6-phosphofructokinase-II	gnl\|CDD\|182361	PRK10294, PRK10294, 6-phosphofructokinase 2; Provisional.	0
NZ_CP021851.1\|WP_025757348.1\|2165133_2165670_+\|YniB-family-protein	gnl\|CDD\|372875	pfam14002, YniB, YniB-like protein. The YniB-like protein family includes the E. coli YniB protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 180 amino acids in length. This family of proteins are integral membrane proteins.	1.22656e-94
NZ_CP021851.1\|WP_025757355.1\|2157044_2158400_+\|6-phospho-beta-glucosidase	gnl\|CDD\|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP021851.1\|WP_025757353.1\|2159361_2161611_-\|catalase-HPII	gnl\|CDD\|236886	PRK11249, katE, hydroperoxidase II; Provisional.	0

>NZ_CP021851.1|WP_025757354.1|2158411_2159161_+|chitin-disaccharide-deacetylase
MENLLIVNADDFGLSKGQNYGIVEACRRGVVTSTTALVNGEAIEHAAQLSREVPDLGVGMHFVLTLGMPLSAMPGLTRDGQLGKWIWEMAEQDALPLEEIARELDCQFNRFVDLFGREPTHIDSHHHVHMIPAIFPLVAEFAQRKGVAMRVDRDVRGLPAYAVATTEGFSSAFYGDAIDEALFLKVLDDSAARGERSLEVMAHPAFVDNTVRKSAYCWPRLAELDVLTSPSLKYAIAERGYRLGTFRDL
>NZ_CP021851.1|WP_025757355.1|2157044_2158400_+|6-phospho-beta-glucosidase
MQKKLKVVTIGGGSSYTPELLEGFLKRYHELPVSELWLVDVAEGQEKLDIIFDLCQRMVAKAGVPLTVHKTLDRRLALKDADFVTTQLRVGQLKARELDERIPLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVQEICPNAWVINFTNPAGMVTEAVYRHTNFKRFIGVCNIPIGMKMFIRDVLALTDSDDLSIDLFGLNHMVFIKDVIVNGKSRFAELLDGVASGRLTAASVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEYYKGGARAQIVQKVEKQLFDLYKDPNLNVKPKELEQRGGAYYSDAACEVINAIYNDKQAEHYVNVPHHGHIDNIPADWAVEMTCILGRDGAKPHPRITHFDEKVMGLIHTIKGFEVAASNAAQSGELNDVLLALNLSPLVHSDRDAEVLATEMILAHEKWLPNFAATVEKLKFQHR
>NZ_CP021851.1|WP_025757356.1|2156116_2156935_+|transcriptional-regulator-ChbR
MEIKTALEQQLFNGKNFHVVIYNKTESASGLHQHDYYEFTIVLTGRYYQEINGKRVLLERGDFVFLPMGSHHQSFYEFGATRILNVGVSRRFFEKHYLPLVPFCFVASQVYRVKNEFMTWIETVIASLNFRDNEFDEFIETVTFYVMNRLRHHREEQQVTDDIPQWLRSTVELMHDKGQFSENALENMVSLSGKSQEYLTRATQRYYRKTPVQIINEIRINFAKKQLEITNYSVTDIAYESGYSSPSLFIKTFKKLTSFTPNSYRKNLTVIN
>NZ_CP021851.1|WP_025757357.1|2155739_2156087_+|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIA
MLDLDSIVAEESAENDLEEVVMGLIINSGQARSLAYAALRQAKQGNFAAAKTMMEQSRTALNEAHLVQTKLIEGDQGEGKMKVSLVLVHAQDHLMTSMLARELVAELIELHEKMQ
>NZ_CP021851.1|WP_025757358.1|2154333_2155692_+|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIC
MSKVIASLEKVLLPFAVKIGKQPHVNAIKNGFIKLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGFKAIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDPLAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIVIGLVVAEMFTFIIRRNWVIRLPDSVPASVSRSFSALIPGFIILSIMGIIAWALSHWGTNFHQIIMDSISTPLASMGGVVGWAYVIFTSLLWFFGVHGSLALAALDSGIMTPWALENVALYQQYGSVDAALAAGKTFHVWAKPMLDSYIFLGGTGATLGLIIAVFIVSRRADHRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFILVQPLLAGITLTAYYLGIIPPITNIAPWTMPAGLGAFFNTNGSVAAFLLAIFNLGIATLLYMPFVAIANKAATVIDEEESEEDIALALKF
>NZ_CP021851.1|WP_008500676.1|2153936_2154254_+|PTS-N,N'-diacetylchitobiose-transporter-subunit-IIB
MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVVIEAFPETLAGEKGQTADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSGLYGKIDGLGVLKAAVAAIKKAAN
>NZ_CP021851.1|WP_003857836.1|2153310_2153655_+|osmotically-inducible-lipoprotein-OsmE
MNKNVAGILSAAAVLTMLAGCTAYDRTKDQFTQPVVKDVKKGMTRSQVAAIAGKPSSEVTMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCAEYDTDPQAPKAQ
>NZ_CP021851.1|WP_025757359.1|2152261_2153089_-|ammonia-dependent-NAD(+)-synthetase
MTLQQEIIQALGAKPAIDANEEIRRSVDFLKAYLKTNSFLKSLVLGISGGQDSTLTGKLCQMAISELREETGDESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGSVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTKGVVVGTDHAAEAITGFFTKYGDGGTDINPIFRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEAALGVTYDNIDDYLEGKTLDEGTAKIIEGWYLKTEHKRRPPITVFDDFWKK
>NZ_CP021851.1|WP_192869218.1|2151268_2152159_-|excinuclease-Cho
MEWYVSRRQSAPRLEFEAAAIYEYPEHLRPWLEALPKLPGVYIFHGESDTLPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWFETAGEMGALLLEARLIKEQQPLFNKRLRRNRQLCSLQITAGKPQVVYAREVDFSHVPNLYGLFANKRAALQALQTLADELQLCYSLLGLEATTRGRACFRSALKRCAGACCGKESVDAHHARLLAGLATISVNCWPWEGAVALKEVGEAMTQYHIVNNWFWLGAVDDINDAATLLRTPAGFDHDGYKILCKPVLAGKFEVIELNGLAAT
>NZ_CP021851.1|WP_025757361.1|2150733_2151291_+|environmental-stress-induced-protein-Ves
MEFFDIRKMPVSLWRNGAGETREICCFPPATRDFHWRASIATIASNGEFSSFPGVDRVITLLEGGEVTLDAGQAFFHTLKHHQPYSFAGDLPVKALLSDGRMAMDFNIMTRRDCCRAKVRVADRTFTTFGTRGGVVFVLSGAWQLGDKLLTADQGASWEEGTHTLRLLEPQGTLLFSEITWLPGH
>NZ_CP021851.1|WP_025757353.1|2159361_2161611_-|catalase-HPII
MSNKDKTHQSPIHGTEESQPGMDSLAPEDGSHRPSPGPSAPGEQPTAPGSLKSPDTGNEKLKSLDPHRKGGEGYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLKAITKADFLSDPDKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPVFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRMINAEGKATFVRFHWKPVAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGLQLIPEEDEFKFDFDLLDPTKLIPEELVPVQLVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRQDIDTNPANYEPNSINDNWPRETPPAPKRGGFESYQERIDGNKIRERSPSFGEYYAHPRLFWNSQTPIEQQHIIGGFSFELSKVVRTYIRERVVDQLAHIDIQLAQSVADNLGITLTDEQRNLAPPKEVNGIKKDPSLSLYAVPGGSIKGRVVAILLNDKTRASDVLGIMQALKTKGVHAKLLYSRMGEVTADDGSVLPVAATFAGAPSLTVDAVIVPGGDITSLLTNGDAVYYLLEAYKHLKPLALSGDARQFKAPLKVAEQGEDGIVEGDNVDDAFMTKLFDLLAAHRVWSRSSKIDQIPA
>NZ_CP021851.1|WP_080276760.1|2161757_2162054_+|cell-division-activator-CedA
MGYHRIFLLQEFVLVNPSLMKPLRQQNRQVISYVPRVEPAPPDHALKVEGFRDVWQLRGKYVAFVLIGEHFRRSPVFTVPESAQRWAMQIRQDEEVEE
>NZ_CP021851.1|WP_025757351.1|2162102_2163494_-|cystine/sulfocysteine:cation-symporter
MNFPLIANVVVFVVLLLLLAQTRHKQWSLAKKVLVGLAMGVVFGLALQAIYGSDNPVLKDSIQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNATQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGSAETARLTAIQTNYVGKVADLTVPQMVLSFIPKNPFADLTGASPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLTAIDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLGIMFVVHGILLGVNGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFSASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPVWIATLVGIVTVSSAGVAGVGGGATFAALIVLPALGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILESEDDAELAHR
>NZ_CP021851.1|WP_025757350.1|2163621_2164212_-|metal-dependent-hydrolase
MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAVLTCLLPDIDHPKSFLGQRLKWVSKPIARAFGHRGFTHSLLAVFGLLTLFYLKVPESWIVPADAIQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRFPILVPQKGNQLERALCMALFAYAVWMPQTLPENSAVRWSSQMINSLQFQFNRFIHHQIEQ
>NZ_CP021851.1|WP_025757349.1|2164313_2164985_-|hexitol-phosphatase-HxpB
MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDINRRNELPDTLGLRIDMVVDLWFAQQPWVGPDRDEVTARIISRAISLVEENRPLLPGVRDAAALCKAQGLKVGLASASPLHMLEKVLTMFELRDSFDALASAEKLPYSKPHPQVYLDCAAKLGLDPLNCVALEDSVNGMVASKAARMRSIVVPAEEGRHDPRFALADVKLTSLTELTARHLLGG
>NZ_CP021851.1|WP_025757348.1|2165133_2165670_+|YniB-family-protein
MTYQQAGRIAVLKRVAGWVIFIPAVISTLISVLKFMYDHSEKQPGINAVMLDFAHVMIEMMRFNTPFLNVFWFNSPTPDFHQQLNIGFWIIYALIFIAMALQASGARMSRQTRFLREGVEDQMILEQAKGPEGMTREQIESRIVVPRHSIFLQIFPLYILPAIVIVAGYFFFSLLGFL
>NZ_CP021851.1|WP_025757347.1|2165706_2166567_-|fructosamine-kinase-family-protein
MWQAISHLLSEQLGEGEIELRNELPGGEIHAAWHLRYAGRDLFVKCDERELLPIFTAEADQLELLSRSKTVTVPQVLAVGSDRDYSFLVMEYLPARPLDAHNAFILGQQLARLHQWSDQPQFGLDFDNDLSTTPQPNAWQRRWSTFFAEQRIGWQLELAAEKGLEFGNIDAIVEHVQQRLASHQPQASLLHGDLWSDNCALGPNGPYIYDPACYWGDRECDLAMLPLHPEQPPQIYDGYQSVSPLPHGFLDRQPVYQLYTLMNRAILFGGEHLVNAQRALERMLAA
>NZ_CP021851.1|WP_025757346.1|2166672_2166963_-|type-V-toxin-antitoxin-system-endoribonuclease-antitoxin-GhoS
MSSGDITRYVVTVNLHEASLTELNELNNAFTRAKFLLTLTDDEGNIHDLGTLAFGLISALTKEEVHALAASLVESVTDKPTEIDVDTWESWQKKEQ
>NZ_CP021851.1|WP_025757345.1|2167069_2168002_-|6-phosphofructokinase-II
MVSIYTLTLSPSLDSATLTPQIYPEGKLRCSAPVFEPGGGGINVARAITHLGGHATAIFPVGGATGEHLVSLLADEQVAVETVEAKDWTRQNLHVHVESSGEQYRFVMPGAKLSDDEFRQLEEKVLTIENGALLVISGSLPPGVSTDKLTALIQAAQQRGIRCIVDSSGEALQAALVPGNLELVKPNQKELSALVNRELTQPDDVRTAAQELVRSGKARRVVVSLGPQGALAVDETSAVQVVPPPMKSQSTVGAGDSMVGAMTLKLAQGASLLEMARYGVAAGSAATINQGTRLCSLADTQKIVDYLSRD
>NZ_CP021851.1|WP_025757344.1|2168297_2169056_+|YdiY-family-protein
MKLLKTVPAALMLAGGVFAAMNAAADDTVFTVMDDPTTAKKPFEGNLNAGYLAQSGNTKSSSLTADSTLTWYGNTTAWSLWGNASNTSANDERSSEKYAVGGRSRYNMTDYDYLFGQASWLTDRYNGYRQRDVFTAGYGRQFLNGPVHSFRFEFGPGVRYDEYTDGDTKTQPLGYASGTYAWQMTDNTKFTQGVSVFGADDTTLNSETALNVAINEHFGLKVAYNVTWNSSPPETAPDHTDRRTTVSLGYKM

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Crispr_ID: NZ_CP021851_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021851_3

2283671-2284002

Orphan

Consensus_repeat	Method
TTACGGGCTTTAGCACGCGCAATGGCCGCTTCGACGGCGGCTTTACGCGG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP021851_3

>merge|NZ_CP021851|3|2283671-2284002|CRISPRCasFinder
TTCTTTGCCTGAACGCGCGCAATGGCGGCGGCGACGGCGGCTTTGCGCGGGTCATCGTTAGCGGCCTGCGGTTGCGTTTCCTGCTGCGCCGCCTTACGGGCTTTAGCACGCGCAATGGCCGCTTCGACGGCGGCTTTACGCGGGTCGACCGGAGTTTCCGCTTCTGCCGCAGGCGCCTGCTGCGCCGCTTTACGGGCTTTAGCACGCGCAATGGCCGCTTCGACGGCCGCTTTACGCGGATCGACCGGGTCCTGTTCTACCACCACCGGTTGCTCTCCGGCTTTGCGGGCCCTGGCGCGGGCGATTGCCGCTTCAACGGCCGCTTTGCGCGG

>NZ_CP021851|3|3|2283671-2284002|CRISPRCasFinder
TTCTTTGCCTGAACGCGCGCAATGGCGGCGGCGACGGCGGCTTTGCGCGG	GTCATCGTTAGCGGCCTGCGGTTGCGTTTCCTGCTGCGCCGCC
TTACGGGCTTTAGCACGCGCAATGGCCGCTTCGACGGCGGCTTTACGCGG	GTCGACCGGAGTTTCCGCTTCTGCCGCAGGCGCCTGCTGCGCCGCT
TTACGGGCTTTAGCACGCGCAATGGCCGCTTCGACGGCCGCTTTACGCGG	ATCGACCGGGTCCTGTTCTACCACCACCGGTTGCTCTCCGGCT
TTGCGGGCCCTGGCGCGGGCGATTGCCGCTTCAACGGCCGCTTTGCGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021851.1\|WP_025758349.1\|2274743_2275400_+\|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl\|CDD\|235555
NZ_CP021851.1\|WP_088244182.1\|2290424_2291597_-\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|224090
NZ_CP021851.1\|WP_025758365.1\|2286889_2287330_-\|DUF2569-domain-containing-protein	unknown	unknown	gnl\|CDD\|371223
NZ_CP021851.1\|WP_025758350.1\|2275525_2276800_+\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NZ_CP021851.1\|WP_025758366.1\|2288233_2289274_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|183212
NZ_CP021851.1\|WP_025758367.1\|2289326_2290328_-\|adenosine-deaminase	unknown	unknown	gnl\|CDD\|236480
NZ_CP021851.1\|WP_025758370.1\|2293415_2294444_+\|Mal-regulon-transcriptional-regulator-MalI	unknown	unknown	gnl\|CDD\|182193
NZ_CP021851.1\|WP_025758353.1\|2277830_2278436_-\|glutathione-transferase-GstA	unknown	unknown	gnl\|CDD\|182533
NZ_CP021851.1\|WP_006174966.1\|2287416_2287632_-\|transcription-modulator-YdgT	unknown	unknown	gnl\|CDD\|182426
NZ_CP021851.1\|WP_025758348.1\|2274362_2274686_+\|C-type-lysozyme-inhibitor	unknown	unknown	gnl\|CDD\|236902
NZ_CP021851.1\|WP_025758360.1\|2282586_2283639_-\|electron-transport-complex-subunit-RsxD	unknown	unknown	gnl\|CDD\|234844
NZ_CP021851.1\|WP_008500570.1\|2280634_2281270_-\|endonuclease-III	unknown	unknown	gnl\|CDD\|182661
NZ_CP021851.1\|WP_025758363.1\|2285653_2286232_-\|electron-transport-complex-subunit-RsxB	unknown	unknown	gnl\|CDD\|235347
NZ_CP021851.1\|WP_025758357.1\|2281266_2281953_-\|electron-transport-complex-subunit-E	unknown	unknown	gnl\|CDD\|237091
NZ_CP021851.1\|WP_008500564.1\|2286231_2286813_-\|electron-transport-complex-subunit-RsxA	unknown	unknown	gnl\|CDD\|235352
NZ_CP021851.1\|WP_025758355.1\|2278534_2280043_-\|dipeptide/tripeptide-permease-DtpA	unknown	unknown	gnl\|CDD\|181969
NZ_CP021851.1\|WP_025758369.1\|2291645_2293238_-\|PTS-maltose-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|182245
NZ_CP021851.1\|WP_025758351.1\|2276866_2277727_+\|pyridoxal-kinase-PdxY	unknown	unknown	gnl\|CDD\|235592
NZ_CP021851.1\|WP_168112406.1\|2287864_2287990_-\|division-septum-protein-Blr	unknown	unknown	gnl\|CDD\|380226
NZ_CP021851.1\|WP_025758358.1\|2281955_2282576_-\|electron-transport-complex-subunit-RsxG	unknown	unknown	gnl\|CDD\|179350

Protein	Function_ID	Function_description	E-value
NZ_CP021851.1\|WP_025758349.1\|2274743_2275400_+\|pyridoxamine-5'-phosphate-oxidase	gnl\|CDD\|235555	PRK05679, PRK05679, pyridoxal 5'-phosphate synthase.	6.38717e-132
NZ_CP021851.1\|WP_088244182.1\|2290424_2291597_-\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	1.73555e-179
NZ_CP021851.1\|WP_025758365.1\|2286889_2287330_-\|DUF2569-domain-containing-protein	gnl\|CDD\|371223	pfam10754, DUF2569, Protein of unknown function (DUF2569). This family is conserved in bacteria. The function is not known, but several members are annotated as being YdgK or a homolog thereof.	7.67111e-38
NZ_CP021851.1\|WP_025758350.1\|2275525_2276800_+\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NZ_CP021851.1\|WP_025758366.1\|2288233_2289274_+\|oxidoreductase	gnl\|CDD\|183212	PRK11579, PRK11579, putative oxidoreductase; Provisional.	0
NZ_CP021851.1\|WP_025758367.1\|2289326_2290328_-\|adenosine-deaminase	gnl\|CDD\|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	9.14692e-154
NZ_CP021851.1\|WP_025758370.1\|2293415_2294444_+\|Mal-regulon-transcriptional-regulator-MalI	gnl\|CDD\|182193	PRK10014, PRK10014, DNA-binding transcriptional repressor MalI; Provisional.	0
NZ_CP021851.1\|WP_025758353.1\|2277830_2278436_-\|glutathione-transferase-GstA	gnl\|CDD\|182533	PRK10542, PRK10542, glutathionine S-transferase; Provisional.	3.32241e-150
NZ_CP021851.1\|WP_006174966.1\|2287416_2287632_-\|transcription-modulator-YdgT	gnl\|CDD\|182426	PRK10391, PRK10391, transcription modulator YdgT.	3.76646e-48
NZ_CP021851.1\|WP_025758348.1\|2274362_2274686_+\|C-type-lysozyme-inhibitor	gnl\|CDD\|236902	PRK11372, PRK11372, C-type lysozyme inhibitor.	1.30098e-77
NZ_CP021851.1\|WP_025758360.1\|2282586_2283639_-\|electron-transport-complex-subunit-RsxD	gnl\|CDD\|234844	PRK00816, rnfD, electron transport complex protein RnfD; Reviewed.	0
NZ_CP021851.1\|WP_008500570.1\|2280634_2281270_-\|endonuclease-III	gnl\|CDD\|182661	PRK10702, PRK10702, endonuclease III; Provisional.	2.35105e-159
NZ_CP021851.1\|WP_025758363.1\|2285653_2286232_-\|electron-transport-complex-subunit-RsxB	gnl\|CDD\|235347	PRK05113, PRK05113, electron transport complex protein RnfB; Provisional.	2.49539e-128
NZ_CP021851.1\|WP_025758357.1\|2281266_2281953_-\|electron-transport-complex-subunit-E	gnl\|CDD\|237091	PRK12405, PRK12405, electron transport complex RsxE subunit; Provisional.	1.2696e-131
NZ_CP021851.1\|WP_008500564.1\|2286231_2286813_-\|electron-transport-complex-subunit-RsxA	gnl\|CDD\|235352	PRK05151, PRK05151, electron transport complex protein RsxA; Provisional.	1.15837e-115
NZ_CP021851.1\|WP_025758355.1\|2278534_2280043_-\|dipeptide/tripeptide-permease-DtpA	gnl\|CDD\|181969	PRK09584, tppB, dipeptide/tripeptide permease DtpA.	0
NZ_CP021851.1\|WP_025758369.1\|2291645_2293238_-\|PTS-maltose-transporter-subunit-IICB	gnl\|CDD\|182245	PRK10110, PRK10110, PTS maltose transporter subunit IICB.	0
NZ_CP021851.1\|WP_025758351.1\|2276866_2277727_+\|pyridoxal-kinase-PdxY	gnl\|CDD\|235592	PRK05756, PRK05756, pyridoxal kinase PdxY.	0
NZ_CP021851.1\|WP_168112406.1\|2287864_2287990_-\|division-septum-protein-Blr	gnl\|CDD\|380226	NF033231, small_Blr, division septum protein Blr. Members of this family are Blr, named beta-lactam resistance protein because mutants have heightened sensitivity to beta-lactam antibiotics, but actually involved in cell division. The protein is very small.	5.54719e-22
NZ_CP021851.1\|WP_025758358.1\|2281955_2282576_-\|electron-transport-complex-subunit-RsxG	gnl\|CDD\|179350	PRK01908, PRK01908, electron transport complex protein RnfG; Validated.	3.46678e-137

>NZ_CP021851.1|WP_025758360.1|2282586_2283639_-|electron-transport-complex-subunit-RsxD
MVFRIASSPYTHNQRQTSRIMMLVCLAALPGIAVQCWFFGWGTLFQILLGCVSALAAEALVLKLRKAAVSRILADNSALLTGLLLAISIPPFAPWWMVVLGTVFAVIIAKQLYGGLGHNPFNPAMIGYVVLLISFPVQMTSWLPPHDIAATVPGFMDALHVIFTGHTALGADMNALRMGVDGISQATPLDTFKTSLHAGHSVEQIMQSAIYRGMLAGAGWQWVNLAYLLGGLFLLQQKAIRWHIPVSFLVTLAVCATLGWVFSPESLASPQMHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHR
>NZ_CP021851.1|WP_025758358.1|2281955_2282576_-|electron-transport-complex-subunit-RsxG
MLKTMQKHGVTLAVFAAVLTGLTALVNALTKTTIEEQASKQQKALFDQVIPSDFYDNDLQKSCFVVDAPQLGKGPHRLFIARKGDKAVGAVMEATAPDGYSGAIQLLVGSDFSGTILGTRVTEHHETPGLGDKIETRLSDWILHFAGKVIHGEEDTAFAVKKDGGEFDQFTGATITPRAVVNAVKRAGLYAETLPAQINNLPACEE
>NZ_CP021851.1|WP_025758357.1|2281266_2281953_-|electron-transport-complex-subunit-E
MSQVKEVIVQGLWKNNSALVQLLGMCPLLAVTSTATNALGLGLATTLVLTLTNLSISALRRWTPSEIRIPIYVMIIASVVSIVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAVKNSPAMSALDGFSIGMGATCAMFVLGSLREILGNGTLFDGADALLGGWAKALRIEVFHTDTPFLLAMLPPGAFIGLGMMLAVKYLIDEKRKRRAAERSVLEGTPEKAS
>NZ_CP021851.1|WP_008500570.1|2280634_2281270_-|endonuclease-III
MNKEKRIAILTRLRDENPHPTTELNFTSPFELLIAVLLSAQATDVSVNKATALLYPVANTPKAMLELGVEGVKSYIKTIGLFNSKAENVIKTCRILLEQHGGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVSNRTNFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVYP
>NZ_CP021851.1|WP_025758355.1|2278534_2280043_-|dipeptide/tripeptide-permease-DtpA
MSTANNKPTDESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAVVYMGMATIAVGNGLFKANPSSLLSTCYSKDDPRLDGAFTMYYMSVNIGSFFSMLATPWLAAKFGWSVAFSLSVVGMLITVVNFAFCQRWVKDYGSKPDFEPVHMGKLLATIVGVVILATIATWLLHNQGIARAVLGVVALGIVVIFAKEAFAMQGAARRKMIVAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGIAFEPEQYQALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGTKFATDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGAAIIAGKIANLMAVPDNVTDPLVSLNVYGTVFMQIGIATAVIAALMLLTAPKLNRMTQDDNKTAEATKTATA
>NZ_CP021851.1|WP_025758353.1|2277830_2278436_-|glutathione-transferase-GstA
MKLFYKPGACSLASHITLRESGKDFTLDGVDLMKKRLENGDDFLAINPKGQVPALLLDDGTLLTEGVAIMQFLADSVPDRQLLAPVSTISRYKTLEWLNYIATELHKGFTPLFRPDTPEEFKPTLRALLEKKLQYVNESLKDEQWIGGSRFTIADAYLFTVLRWARAVKLNLEGLDHIASYMKRVAERPAVAAALKAEGLS
>NZ_CP021851.1|WP_025758351.1|2276866_2277727_+|pyridoxal-kinase-PdxY
MKNILAIQSHVVFGHAGNSAAEFPMRRLGVNVWPLNTVQFSNHTQYGKWTGCVMPPSHLTDVVQGIADIDQLKRCDAVLSGYLGSAEQGEHILGIVRQVKAANPAAKYFCDPVMGHPEKGCIVAPGVAEFHVRHALPASDIIAPNLIELEILCEHPVNSVEEAVSASRELIAQGPEVVLVKHLARAGLSQDRFEMLLVTKDDAWHISRPLVDFGQRQPVGVGDVTSGLLLVKLLQGAALQDALEHVTAAVYEIMMATKAMQEYELQVVAAQDRIAKPEHYFSATRL
>NZ_CP021851.1|WP_025758350.1|2275525_2276800_+|tyrosine--tRNA-ligase
MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQMAGHKPVALVGGATGLIGDPSFKAAERKLNTEDTVQEWVDKIRKQVAPFLDFDCGDNAAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNKLHGVSLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMDIAEINALEEEDKNSGKAPRAQYVLADEVTKLVHGEEGLAAAKRITASLFNGTLSDLSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQADPEYTFVDGDRLYGRYTLLRRGKKNYCLVCWK
>NZ_CP021851.1|WP_025758349.1|2274743_2275400_+|pyridoxamine-5'-phosphate-oxidase
MSDNDELQQIAHLRREYTKGGLRRQDLPAEPLVLFERWLKQACEAKLADPTAMVVATVDENGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHHLENNPRISLLFPWHMLERQVMVTGKAERLSTLEVVKYFHSRPRDSQIGAWVSKQSSRISARGVLESKFLELKQKFQQGEIPLPSFWGGFRIPIEQIEFWQGGEHRLHDRFLYQREEGGWKIDRLAP
>NZ_CP021851.1|WP_025758348.1|2274362_2274686_+|C-type-lysozyme-inhibitor
MKKLLLIAAPLLLSGCSVYNQLLERMQTDTLEYRCDEKPLTVKLNNPRQEASFVYDNKLLTLKQGISASGARYTDGIYVFWSKGDSATVYKRDRIVLNNCQLENPKR
>NZ_CP021851.1|WP_025758363.1|2285653_2286232_-|electron-transport-complex-subunit-RsxB
MNAIWIAIASISVLGLVFGLILGYASRRFAVEDDPVVEKIDELLPQSQCGQCGYPGCRPYAEAVGVQGEKINRCAPGGEAVMLKIAALLNVDPQPVDGDADVQEPVRALAVIDEANCIGCTKCIQACPVDAIVGATRAMHTVVADLCTGCNLCVAPCPTQCIELRPVEPTTESWKWDLQTIPVRIIPVEQHA
>NZ_CP021851.1|WP_008500564.1|2286231_2286813_-|electron-transport-complex-subunit-RsxA
MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWWIDTWILIPLGLTYLRTLAFILVIAVVVQFTEMVVRKTSPALYRLLGIFLPLITTNCAVLGVALLNINLGHNFMQSALYGFSAAVGFSLVMVLFASIRERLAAADIPAPFRGNAIALVTAGLMSLAFMGFSGLVKL
>NZ_CP021851.1|WP_025758365.1|2286889_2287330_-|DUF2569-domain-containing-protein
MTATPGERIGGWLIAPLAWLLVALLSASLALLLYTTALITPHAIQTLMSQSVLNIAMWFVSFVFAIGMWYYTLWLTIAFFKRRKSVPKHYIIWLLVSVLLAVKAFAFSPVSDALAVRQLLFPLLAAALLVPYFKRSTRVKNTFVNP
>NZ_CP021851.1|WP_006174966.1|2287416_2287632_-|transcription-modulator-YdgT
MTVQDYLLKFRKINSLESLEKLFDHLNYTLSDNQEIINMYRAADHRRAELVSGGRLFNVGEVPKSVWRYVL
>NZ_CP021851.1|WP_168112406.1|2287864_2287990_-|division-septum-protein-Blr
MNRIIELAGWIVLGVSVILLGVASHIDNYQPPEPVTVAQPK
>NZ_CP021851.1|WP_025758366.1|2288233_2289274_+|oxidoreductase
MSDNIRVGLIGYGYASKTFHAPLIAGTPGMALAAVSSSDAAKVHADWPSVPVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRLLSVFHNRRWDSDFLTVKRLLGEGTLGEILFFESHFDRFRPQVRNRWREQAGPGSGIWYDLAPHLLDQAVNLFGLPVSMTVDLAQLRPGAQTTDYFHAVLSYPQRRIVLHGTMVAAAESARYIVHGTRGSYVKFGLDPQEDRLKNGERLPQEDWGYDMRDGVVTRVEGEELVEETLLTIPGNYPAYYAAIRDALNGSGENPVPASQAIQIMELIELGIESAKHRATLCLA
>NZ_CP021851.1|WP_025758367.1|2289326_2290328_-|adenosine-deaminase
MIDTRLPLTDIHRHLDGNIRAQTILDLGRQFNLTLPAQTLDALIPHVQVTSNEPDLVSFLSKLDWGVKMLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMTHNLPVAGVVEAVIEGVREGCKAFDVQARLIGIMSRTFGEAACLQELEALLAHRDAITAVDLAGDELGFPGSLFLSHFNRARDAGWHVTVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAEQRIGIESCLTSNIQTSTVATLAQHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYNIAAPQAGLSREQIRQAQINGLEMAFLTPAEKQALKDKVARG
>NZ_CP021851.1|WP_088244182.1|2290424_2291597_-|pyridoxal-phosphate-dependent-aminotransferase
MFDFSTVVDRHGTWCTQWDYVADRFGAADLLPFTISDMDFATAPCITDALHERIHHGVFGYSRWKNDEFLAAIAHWFEQRFNCQIDTESVVYGPSVIYMVSELIRLWSNPGDGVVVHTPAYDAFYKAIEGNARQMVTVEMQKQPTGWQGNMTALEAALAKPENKILLLCSPQNPTGKVWTRDELTHMAELCARYDVAVISDEIHMDMVWGEHRHTPWSAVARGKWALLTSGSKSFNIPALTGAYGLIGDEASRNGYLSALKGRDGLSSPSVLALTAHIAAYQQGAPWLDALRHYLEDNLLYIAQELNGAFPELNWQPPEATYLAWIDLRPLNLDDRSLQKVLIEQQKVAIMPGYTYGNEGNGFVRLNAGCPRSKLEQGVQRLIAGINTLR
>NZ_CP021851.1|WP_025758369.1|2291645_2293238_-|PTS-maltose-transporter-subunit-IICB
MTAKAAQKISLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSKDVITLIPFLGAPALQAIFIWMSKVGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGFVGYAVMNLAVNFWLTAKGILPTTDAAVLKANNIQSVIGIQSIDTGILGAVIAGVIIWMLHERFHNIRLPDALAFFGGTRFVPIITLVVMGLFGLIIPLIWPVFAMGINGIGRIINGAGDFGPMIFGTGERLLLPFGLQHILVALIRFTEAGGTMEVCGHDVSGALTIFQAQLSCPTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGVIACVVGGTTEPIEFLFLFVAPVLYLIHAVLTGLGFTVMAVLGVTIGNTDGNVIDFVVFGILHGLSTKWYLVPVVAAIWFAVYYGIFRFAITRFNLKTPGRDTDTATSVEQAVAGTVGKSGYNTPAILAALGGAENITSLDNCITRLRLSVADMSKVDTNALKANRAIGVVQLNQHNLQVVIGPQVQSVKDELATLMRTVEA
>NZ_CP021851.1|WP_025758370.1|2293415_2294444_+|Mal-regulon-transcriptional-regulator-MalI
MAVAKKITINDVALAAGVSVSTVSLVLSGKGRISPATGQRVNEAVEQLGFVRNRQASALRGGQSGVIGLIVRDLTSPFYAELTAGLTEALEAQGRMVFLLHGGREADQLLSRLDMLLTQGVDGVIVAGASGVGSELCERAAEKGVPLVFASRASYLDEADTLRPDNMQAAQMLTEHLIRRGHQRIAWLGGKSSSLTRAERVGGYCATLIKYGLPFHSEWVVECESSQKKAAEAIGALLRSSPTISAVICYNDVIAMGAWFGLIRAGRQSGEGGVETFFGHQVALGAFADVGENALDDLPIVWATTPAREMGYTLADRIMQRIDNTDVQAGHQIVAARLVTVK

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Crispr_ID: NZ_CP021851_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021851_4

3728094-3728372

Orphan

Consensus_repeat	Method
GGGCGATTAGCTCAGTTGGTAGAGCATCTCCTTTACACGGAGGGGGTCGGCGGTTC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP021851_4

>merge|NZ_CP021851|4|3728094-3728372|PILER-CR
GGGTGATTAGCTCAGTTGGTAGAGCATCTCCTTTACACGGAGGGGGTCGGCGGTTCGAGCCCGTCATCACCCACCATCTACTTTACGTAGACTCGCAGTGTAGATAAGGATTGAGATTGGGCGATTAGCTCAGTTGGTAGAGCATCTCCTTTACACGGAGGGGGTCGGCGGTTCAAGCCCGTCATCGCCCACCATTCTCACCTTATCGCAGCAGTTCCGAAATGGGCGATTAGCTCAGTTGGTAGAGCATCTCCTTTACACGGAGGGGGTCGGCGGTTC

>NZ_CP021851|4|1|3728094-3728372|PILER-CR
GGGTGATTAGCTCAGTTGGTAGAGCATCTCCTTTACACGGAGGGGGTCGGCGGTTC	GAGCCCGTCATCACCCACCATCTACTTTACGTAGACTCGCAGTGTAGATAAGGATTGAGATT
GGGCGATTAGCTCAGTTGGTAGAGCATCTCCTTTACACGGAGGGGGTCGGCGGTTC	AAGCCCGTCATCGCCCACCATTCTCACCTTATCGCAGCAGTTCCGAAAT
GGGCGATTAGCTCAGTTGGTAGAGCATCTCCTTTACACGGAGGGGGTCGGCGGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021851.1\|WP_000487600.1\|3736679_3736937_+\|phosphocarrier-protein-Hpr	unknown	unknown	gnl\|CDD\|182777
NZ_CP021851.1\|WP_045286553.1\|3728933_3729869_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP021851.1\|WP_025758770.1\|3731167_3733183_-\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NZ_CP021851.1\|WP_025758764.1\|3726002_3726374_+\|putative-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|369180
NZ_CP021851.1\|WP_025758761.1\|3722803_3724993_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP021851.1\|WP_025758757.1\|3715398_3716634_+\|ion-channel-protein	unknown	unknown	gnl\|CDD\|235148
NZ_CP021851.1\|WP_025758771.1\|3733252_3734236_-\|cell-division-protein-ZipA	unknown	unknown	gnl\|CDD\|235124
NZ_CP021851.1\|WP_025758763.1\|3725617_3725986_+\|putative-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|369180
NZ_CP021851.1\|WP_088244323.1\|3726419_3727835_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NZ_CP021851.1\|WP_025758767.1\|3728598_3728937_+\|FlxA-like-family-protein	unknown	unknown	gnl\|CDD\|379537
NZ_CP021851.1\|WP_025758760.1\|3719983_3721222_-\|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl\|CDD\|234815
NZ_CP021851.1\|WP_025758773.1\|3734465_3735227_+\|sulfate-transporter-CysZ	unknown	unknown	gnl\|CDD\|179898
NZ_CP021851.1\|WP_008501604.1\|3736981_3738709_+\|phosphoenolpyruvate-protein-phosphotransferase-PtsI	unknown	unknown	gnl\|CDD\|183017
NZ_CP021851.1\|WP_003861328.1\|3730950_3731166_-\|DUF3820-family-protein	unknown	unknown	gnl\|CDD\|226061
NZ_CP021851.1\|WP_025758756.1\|3714226_3715192_-\|glucokinase	unknown	unknown	gnl\|CDD\|234716
NZ_CP021851.1\|WP_014884739.1\|3735390_3736362_+\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273465
NZ_CP021851.1\|WP_025758758.1\|3718478_3719477_+\|L-glyceraldehyde-3-phosphate-reductase	unknown	unknown	gnl\|CDD\|381377
NZ_CP021851.1\|WP_025758759.1\|3719603_3719954_+\|DUF2502-domain-containing-protein	unknown	unknown	gnl\|CDD\|371199
NZ_CP021851.1\|WP_008501591.1\|3721571_3722759_+\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_CP021851.1\|WP_023325832.1\|3729958_3730954_+\|bile-acid:sodium-symporter	unknown	unknown	gnl\|CDD\|372642

Protein	Function_ID	Function_description	E-value
NZ_CP021851.1\|WP_000487600.1\|3736679_3736937_+\|phosphocarrier-protein-Hpr	gnl\|CDD\|182777	PRK10850, PRK10850, phosphocarrier protein Hpr.	1.90054e-43
NZ_CP021851.1\|WP_045286553.1\|3728933_3729869_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.45605e-68
NZ_CP021851.1\|WP_025758770.1\|3731167_3733183_-\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP021851.1\|WP_025758764.1\|3726002_3726374_+\|putative-DNA-binding-transcriptional-regulator	gnl\|CDD\|369180	pfam07037, DUF1323, Putative transcription regulator (DUF1323). This family consists of several hypothetical Enterobacterial proteins of around 120 residues in length. This family appears to have an HTH domain and is therefore likely to act as a transcriptional regulator.	4.95722e-43
NZ_CP021851.1\|WP_025758761.1\|3722803_3724993_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.1228e-77
NZ_CP021851.1\|WP_025758757.1\|3715398_3716634_+\|ion-channel-protein	gnl\|CDD\|235148	PRK03655, PRK03655, putative ion channel protein; Provisional.	0
NZ_CP021851.1\|WP_025758771.1\|3733252_3734236_-\|cell-division-protein-ZipA	gnl\|CDD\|235124	PRK03427, PRK03427, cell division protein ZipA; Provisional.	0
NZ_CP021851.1\|WP_025758763.1\|3725617_3725986_+\|putative-DNA-binding-transcriptional-regulator	gnl\|CDD\|369180	pfam07037, DUF1323, Putative transcription regulator (DUF1323). This family consists of several hypothetical Enterobacterial proteins of around 120 residues in length. This family appears to have an HTH domain and is therefore likely to act as a transcriptional regulator.	4.06182e-53
NZ_CP021851.1\|WP_088244323.1\|3726419_3727835_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP021851.1\|WP_025758767.1\|3728598_3728937_+\|FlxA-like-family-protein	gnl\|CDD\|379537	pfam14282, FlxA, FlxA-like protein. This family includes FlxA from E. coli. The expression of FlxA is regulated by the FliA sigma factor, a transcription factor specific for class 3 flagellar operons. However FlxA is not required for flagellar function or formation.	2.99941e-05
NZ_CP021851.1\|WP_025758760.1\|3719983_3721222_-\|Nramp-family-divalent-metal-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	0
NZ_CP021851.1\|WP_025758773.1\|3734465_3735227_+\|sulfate-transporter-CysZ	gnl\|CDD\|179898	PRK04949, PRK04949, putative sulfate transport protein CysZ; Validated.	1.7994e-153
NZ_CP021851.1\|WP_008501604.1\|3736981_3738709_+\|phosphoenolpyruvate-protein-phosphotransferase-PtsI	gnl\|CDD\|183017	PRK11177, PRK11177, phosphoenolpyruvate-protein phosphotransferase PtsI.	0
NZ_CP021851.1\|WP_003861328.1\|3730950_3731166_-\|DUF3820-family-protein	gnl\|CDD\|226061	COG3530, COG3530, Uncharacterized protein conserved in bacteria [Function unknown].	1.18467e-32
NZ_CP021851.1\|WP_025758756.1\|3714226_3715192_-\|glucokinase	gnl\|CDD\|234716	PRK00292, glk, glucokinase; Provisional.	0
NZ_CP021851.1\|WP_014884739.1\|3735390_3736362_+\|cysteine-synthase-A	gnl\|CDD\|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	0
NZ_CP021851.1\|WP_025758758.1\|3718478_3719477_+\|L-glyceraldehyde-3-phosphate-reductase	gnl\|CDD\|381377	cd19151, AKR_AKR14A2, Salmonella enterica aldo-keto reductase (AKR) and similar protein. Salmonella enterica AKR is a founding member of aldo-keto reductase family 14 member A2 (AKR14A2).	0
NZ_CP021851.1\|WP_025758759.1\|3719603_3719954_+\|DUF2502-domain-containing-protein	gnl\|CDD\|371199	pfam10697, DUF2502, Protein of unknown function (DUF2502). Members of this family are all Gammaproteobacteria. The function is not known.	9.06008e-11
NZ_CP021851.1\|WP_008501591.1\|3721571_3722759_+\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	1.12503e-161
NZ_CP021851.1\|WP_023325832.1\|3729958_3730954_+\|bile-acid:sodium-symporter	gnl\|CDD\|372642	pfam13593, SBF_like, SBF-like CPA transporter family (DUF4137). These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.	2.0888e-122

>NZ_CP021851.1|WP_088244323.1|3726419_3727835_-|glutamate--tRNA-ligase
MKIKTRFAPSPTGYLHVGGARTALYSWLFARHNKGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLVAGTAYKCYCSKERLDALREEQMANGEKPRYDGRCRHDHSEHAADEPCVVRFANPQEGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVVRGEDHINNTPRQINILKALNAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWAHGDQEIFSREEMIELFSLSSVSKSASAFNTDKLLWLNHHYINTMQPEYVATYLQWHIEQANIDTRTGPELADLVRLLGERCKTLKEIAESCRYFYEEFDEFDADAAKKHLRPVARQPLEVVRDKLAALTEWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKSRSVARINKALDFIAERENQQ
>NZ_CP021851.1|WP_025758764.1|3726002_3726374_+|putative-DNA-binding-transcriptional-regulator
MTTEELALILGVARQTVNRWIRQQAWKTEGLNGVKGGRARLIHVDARVKEYIKRLPAIRSRQAVYHLAEATTAYHSSPTSLRPGIIETLENMTELEQKRLEDFLKREGIRGFLTRLDIAEHNA
>NZ_CP021851.1|WP_025758763.1|3725617_3725986_+|putative-DNA-binding-transcriptional-regulator
MIKERMTPEELALLTGYSRQTINKWVRKEGWITSPKPGVQGGKARLVHVNEKVRDFIRSARRATETPELPEGVSHDSSLHTLLLTLANEMTPEEQKQMTSLLLREGITGLLQRLGIRDRNEY
>NZ_CP021851.1|WP_025758761.1|3722803_3724993_-|EAL-domain-containing-protein
MNRKTYNNVKIFIIALALCLITVPVSRYLSPRAMVNGHDVYLAWLPLSVMLAIILLFGRRAILPILLGFTVTNLFYVNLAPLQYSVLLFCQTFALFAVCGVLRLILGKRWRYCIPNKHIGLRIFWLGFIVPVGIKLSMYMAGYLFDFPLTISTFFGEGTVIYNVVDIQSLICAALIFTMMFYYPLRMIINPRYAVTFWRRSVKPVFLHKNSLYIFVWLILLSFILVILCGPFESPVIAGYLMPLIFILFTLAISRLTYALISLLWATSALLLLNYNYNFLNGVESGHSLSFILSVLISFAICLLYMSRIYQRSEWLKRGWQGRALTDPLTGLPNIRALEDYLEIHPAAKVCILRMDNLEFLSRHYGILMRVHCKRTIATSLQPLLQKDEMIFQLPGSELVLVLLGSDIAERLQTMIDRLNSSKIFWNNTGLDIEFGASWGMVENGEKLHHTLGQLSWLAEQACGAHNVLALTNSLEAASGQTTERVLMLARIKHALDAGQFHLYAQPIQKADGSGYNEILARMESEGEIITPDRFIPLIAQFNLSHRFDMCIMEKLLMWLRANPETQAGARFSVNLMPLTLMQKEVAGEICALFERYGVAPQAVVIEITEEQAFSNSGSSINNIQQLRDYGFRIAIDDFGTGYANYERLRRLQADIIKIDGCFVKDICTDDMDAMIVQSMCNLAKTKSLCVVAEYVETPAQREMLLRCGVDYLQGYLIGKPRPLEELRA
>NZ_CP021851.1|WP_008501591.1|3721571_3722759_+|NupC/NupG-family-nucleoside-CNT-transporter
MDRVLHFVLALVVVTALALLVSTDRKKIRIRYVVQLLVIEVLLAWFFLNSNVGLGFVKGFSEMFEKLLGFANEGTNFVFGKMNDEGLAFFFLKVLCPIVFISALIGILQHIRVLPFVIRGIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGKMSRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVDASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALISALNALFAAVLGISFQGILGYIFYPVAWVMGVPAHEALQVGSIMATKLVSNEFVAMMDLQKIASTLSPRAEGILSVFLVSFANFSSIGIIAGAIKGLNEEQGNVVSRFGLKLVYGSTLVSVLSASIAALVL
>NZ_CP021851.1|WP_025758760.1|3719983_3721222_-|Nramp-family-divalent-metal-transporter
MTNSRVEGSSGRAARKLRFALMGPAFIAAIGYIDPGNFATNIQAGASFGYKLLWVVVWANLMAMLIQMLSAKLGIATGKNLAEQIRDHYPRPAVWLYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMLIPDLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRKERYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFNGHTGIADLDQAYLTLEPLLSHAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSNKTLMGELVNSTLVKRTGWAIVVVVVALNLWLLIGTALGL
>NZ_CP021851.1|WP_025758759.1|3719603_3719954_+|DUF2502-domain-containing-protein
MFRSLILAAVLLASAPLVATAGEITLLPSVKLQIGDRDDYGRYWDGGYWRDRDYWHRHYEWRGDRWWKHDNGRHRGWYKDNAYERGYREGWNDRDDRRGGWGRGKGHGHGHGHGRH
>NZ_CP021851.1|WP_025758758.1|3718478_3719477_+|L-glyceraldehyde-3-phosphate-reductase
MGYQPDQNRYQTMEYRRCGRSGLSLPAISLGLWHNFGDATLLENSRQLLQRAFDLGITHFDLANNYGPPPGSAERNFGRILQEDFLPWRDELIISTKAGYTMWEGPYGDWGSRKYLLASLDQSLKRMGLEYVDIFYHHRPDPQTPLQETMKALDHVVRQGKALYVGLSNYPAVLARKAIDILNDLGTPCLIHQPKYSMFERAPEAGLLEVLQEKGVGCIPFSPLAGGQLTNRYLNGIPADSRAASDSKFLNPEQITEEKLETVRKLNAMAEGRGQKLSQMALAWILRHEAVTSVLIGASKTTQIEDAVGMLKNRHFSAEELATIDGILNGSK
>NZ_CP021851.1|WP_025758757.1|3715398_3716634_+|ion-channel-protein
MLHPRARTMLLLAIPALIIGVVSSLVLIVVMKVASVLQTMLWTALPVKLGVAADSPAWIVIMLTLTGVAVGLVIRFSPGHAGPDPAQEPLIGAPVPPSALPGLIIALIMGLAGGVSLGPEHPIMAVNIGMAVFLGSRILPRVSALDWTILASAGTIGALFGTPVAAALIFSQTLSSNNDVPLWDKLFAPLMAAAAGALTTSLFFHPHFSLSLPHYGQMQIADIFSGAIVVAIAIALGMVAVWCLPRLHRLVHKLKHPVLILGTGGLILGVLGAIGGTITLFKGLDEMQQLAFSQVFSVSDYLLFALIKLAALVVAAACGFRGGRIFPAVFIGVALGLMLHEHVDAVPAAITVSCSILGLVLVVTRDAWLSLFMAAVVVPDTTLIPLLCIVMLPAWLLLAGKPMMMAWRNDR
>NZ_CP021851.1|WP_025758756.1|3714226_3715192_-|glucokinase
MTKYALVGDVGGTNARLALCDVSSGEISRAKTYSGLDYPSLEAVVRVYLEEHQVSVEDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFAHLEIINDFTAVSMAIPMLKPEHLIQFGGAEPVEGKPIAVYGAGTGLGVSHLVHVAQRWVSLPGEGGHVDFAPNSEEEGIILEELRAEIGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPKDVTERALADSCIDCRRALSLFCVIMGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFRSYVQDIPVYLIVHDNPGLLGAGAHLRQVLGQIL
>NZ_CP021851.1|WP_025758767.1|3728598_3728937_+|FlxA-like-family-protein
MTTIQASTQPIQTSGGSGTSSSNDIAAQISRILDKIKKLTQQLKELANSPGSTDEKKKQQELIQTQIKVLQAQLAALQRQQAEEAQKKQDQKLGKVEGVNSPSDSHQIDIYI
>NZ_CP021851.1|WP_045286553.1|3728933_3729869_-|LysR-family-transcriptional-regulator
MNYSLRQLRIFVTVAQARSFSRAGEMIGLSQSAVSHSVKELENQTGVRLLDRTTREVVLTEAGQQLALRLERLLDELNSTLRDVGRLGQQLSGTVRVAASQTISAHLIPQCIAEGNQRYPDIDFVLHDRPQQWVLESIRQGDVDFGIVIDPGQVSDLTCESVLSEPFLLLCRDDDPLAILPEVSWQRLQGANLVLQDYASGSRPLIDSALVNQGVTATIVQEIGHPATLFPMVEAGIGISVLPALALPLPQGSRLAVKRLTPVVERKLMLVRRKNRSLSGAAQAIWEVVRIQAQRLTEARIRDPLFNASED
>NZ_CP021851.1|WP_023325832.1|3729958_3730954_+|bile-acid:sodium-symporter
MKLFRIVDPFTLTLVVTVLLASFFPARGGFVPFFEGLTTAAIALLFFMHGAKLSREAIIAGGSHWRLHLWVMCSTFILFPILGVLFAWWAPVNVDPALYTGFLYLCILPATVQSAIAFTSLAGGNVAAAVCSASASSLLGIFVSPLLVGLLMNMHGAEGNLEQVGKICLQLLLPFVLGHLSRPWTGAFVAKHKKWISKTDQSSILLVVYSAFSEAVVNGIWHKVGAGSLLFIVVVSLILLAIVIAVNVFVARKCGFNKADEITIVFCGSKKSLANGIPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEKLAQEETRAAKA
>NZ_CP021851.1|WP_003861328.1|3730950_3731166_-|DUF3820-family-protein
MEKEQLVEIANTEMPFGKYKGRRLIDLPEEYLLWFARKDEFPAGRLGELMAITLLIKTEGLTQLVQPLKRP
>NZ_CP021851.1|WP_025758770.1|3731167_3733183_-|NAD-dependent-DNA-ligase-LigA
MDSIEQQLTELRTTLRHHEYLYHVMDAPEVPDAEYDRLMRELRELEAQHPELITPDSPTQRVGAEPLGAFSQVRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSSDSLTWCCELKLDGLAVSLLYENGVLVRAATRGDGTTGEDITTNVRTIRAIPLKLQGDNIPARLEVRGEVFLPQAGFEKINEEARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSNRVQLCDSPEAVLAFYHKVEEDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVESERPDDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLDRMGPKSAQNVVNALEAAKETTFARFLYALGIREVGEATAAGLAAYYGTLEALENASIDELQKVPDVGIVVATHVFNFFAEESNREVIGKLLAEGIKWPAPVVVNAEEIDSPFAGKTVVLTGSLSQLSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMMRLLGE
>NZ_CP021851.1|WP_025758771.1|3733252_3734236_-|cell-division-protein-ZipA
MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSSRDDDDSEDDIDGIDDDGVGEVRVHRVNTAPGAAHGEHEAPRPAQHQYQPPYASAQPRQHAPQPVEEPVRQPPQQPVHQQPAAPQPVQQQPVQQPVQQQPAQPVQQPQQPVHVQPAPQPAPAPHVEPEPVAEPEPVVEKPQRKEAVIIMNVAAHQGSHLNGDVLLNSIQQAGFKFGDMNIFHRHLSPDGSGPALFSLANMVNPGTFDPEMTGDFVTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDRIREVKEANA
>NZ_CP021851.1|WP_025758773.1|3734465_3735227_+|sulfate-transporter-CysZ
MVSTSSSPPRSGVWYFSQGWKLVSLPGIRRFVILPLFINIILMGGAFWWLFTKLESWIPSLMSHVPDWLQWLNYLLWPVAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGILGIMKDLPRIMKREWQKFVWYLPRAIVLLILYFVPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKVANMQFGALTSLFTMIPFLNLFIMPVAVCGATAMWVDCYRAKHALWK
>NZ_CP021851.1|WP_014884739.1|3735390_3736362_+|cysteine-synthase-A
MSKIYEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIVASDPAKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFISGVGTGGTLTGVSRYIKGTKGKKDLITVAVEPTDSPVITQALAGEELKPGPHKIQGIGAGFIPGNLDLKLIDKVVTITNEEAISTARRLMDEEGILAGISSGAAVAAALKLQEDEAFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ
>NZ_CP021851.1|WP_000487600.1|3736679_3736937_+|phosphocarrier-protein-Hpr
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE
>NZ_CP021851.1|WP_008501604.1|3736981_3738709_+|phosphoenolpyruvate-protein-phosphotransferase-PtsI
MISGILASPGIAFGKALLLKEDEIVIDRKKISADKVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKGMTADAAAHEVIEGQATALEELDDEYLKERAADVRDIGKRLLRNILGLAIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNGDYLILDAVNNLVYVNPTNEEIEKLRAVQEQVATEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVDGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAVRIAMDRKEILRDQVRAILRASAFGKLRIMFPMIISVEEVRALKKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVNKFIEEKTIC

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

425830 : 510157

Escherichia_phage(23.81%)

transposase,integrase,protease

attL 435171:435195|attR 516023:516037

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_055386957.1\|425830_426502_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_032742891.1\|427472_428372_+\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_161493417.1\|429035_429395_+	hypothetical protein	NA	NA	NA	NA
WP_032742894.1\|429490_429856_+	hypothetical protein	NA	NA	NA	NA
WP_032742899.1\|429937_430585_+	hypothetical protein	NA	NA	NA	NA
WP_032742901.1\|430685_431672_+	DUF1738 domain-containing protein	A0A1V0EEV1	Caulobacter_phage	3.8e-50	39.9
WP_032742903.1\|431777_432710_+	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_000427619.1\|433321_434326_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
435171:435195	attL	NA	NA	NA	NA
WP_004388336.1\|439024_439459_+	copper resistance system metallochaperone PcoE	NA	NA	NA	NA
435171:435195	attL	NA	NA	NA	NA
WP_000427619.1\|440080_441085_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_004393990.1\|441272_441881_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_022652304.1\|441877_443029_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_022652303.1\|443025_444231_+	ABC transporter permease	NA	NA	NA	NA
WP_004393997.1\|444232_444943_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-31	38.3
WP_003056106.1\|444971_445445_+	cytochrome c	NA	NA	NA	NA
WP_088244041.1\|445431_446919_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_172688984.1\|447076_448759_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_028604704.1\|448761_449670_+	TniB family NTP-binding protein	NA	NA	NA	NA
WP_088244043.1\|449666_450884_+	TniQ family protein	NA	NA	NA	NA
WP_003155741.1\|450945_451569_+	recombinase family protein	A0A0C4UR34	Shigella_phage	1.7e-35	47.6
WP_012695458.1\|451722_452277_-	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
WP_012695457.1\|452375_453116_-	subclass B1 metallo-beta-lactamase IMP-8	NA	NA	NA	NA
WP_000845054.1\|453268_454282_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	6.1e-72	45.5
WP_001162012.1\|454603_455161_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
WP_001138073.1\|455163_458136_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
457364:457388	attR	NA	NA	NA	NA
WP_025760127.1\|458847_459435_+	cellulose biosynthesis protein BcsO	NA	NA	NA	NA
457364:457388	attR	NA	NA	NA	NA
WP_025760128.1\|459425_460229_+	cellulose synthase operon protein YhjQ	NA	NA	NA	NA
WP_025760129.1\|460246_462361_+	UDP-forming cellulose synthase catalytic subunit	NA	NA	NA	NA
WP_025760130.1\|462357_464652_+	cellulose biosynthesis cyclic di-GMP-binding regulatory protein BcsB	NA	NA	NA	NA
WP_032672713.1\|464665_468706_+	cellulose biosynthesis protein BcsC	NA	NA	NA	NA
WP_025760132.1\|468705_469185_+	cellulose synthase	NA	NA	NA	NA
WP_025760133.1\|469193_470192_+	endoglucanase	NA	NA	NA	NA
WP_088244044.1\|472237_475246_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	64.0
WP_004098989.1\|475405_475975_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-40	47.8
WP_004098990.1\|475982_477374_+	SIR2 family protein	NA	NA	NA	NA
WP_004098991.1\|477370_479437_+	DUF87 domain-containing protein	NA	NA	NA	NA
WP_025760437.1\|479814_479949_-	stationary-phase-induced ribosome-associated protein	NA	NA	NA	NA
WP_173675451.1\|480116_481193_-	mannuronate-specific alginate lyase	NA	NA	NA	NA
WP_025760430.1\|481251_482796_-	methyl-accepting chemotaxis protein	A0A1B0V854	Salmonella_phage	2.3e-38	54.7
WP_088244045.1\|483183_484164_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	1.5e-184	98.8
WP_023327680.1\|484355_485060_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	2.0e-138	99.6
WP_088244426.1\|485084_486470_+	DUF4158 domain-containing protein	A0A1B0V7H9	Salmonella_phage	1.3e-112	31.6
WP_000427619.1\|486548_487553_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_001137910.1\|488012_488333_+	DUF134 domain-containing protein	NA	NA	NA	NA
WP_001531258.1\|488455_489238_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	6.1e-136	96.5
WP_000627495.1\|489234_490257_-\|transposase	IS21-like element ISSen3 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-174	85.3
WP_016241611.1\|490890_491328_+	PaaI family thioesterase	NA	NA	NA	NA
WP_000043177.1\|491442_491919_+	DNA starvation/stationary phase protection protein	A0A2H4N7L5	Lake_Baikal_phage	4.1e-18	31.7
WP_032672761.1\|492223_492574_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_025760366.1\|492735_494394_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_025760365.1\|494463_495495_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_088244011.1\|495679_496660_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	5.2e-185	98.8
WP_025760312.1\|496835_497702_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_001515173.1\|497704_498028_-	helix-turn-helix transcriptional regulator	F8TVE5	EBPR_siphovirus	7.5e-08	41.7
WP_025760313.1\|498210_499176_+	nucleotidyltransferase	NA	NA	NA	NA
WP_025760314.1\|499183_499702_+	hypothetical protein	NA	NA	NA	NA
WP_032742913.1\|499698_500631_+	AAA family ATPase	NA	NA	NA	NA
WP_053287146.1\|500721_501447_+	hypothetical protein	NA	NA	NA	NA
WP_053287147.1\|501463_501691_-	hypothetical protein	NA	NA	NA	NA
WP_077254457.1\|501686_502283_+	toll/interleukin-1 receptor domain-containing protein	A0A097BYB4	Enterococcus_phage	2.8e-08	26.6
WP_025760317.1\|502418_503618_+	type II restriction endonuclease	E5E3X4	Burkholderia_phage	1.1e-32	39.1
WP_032742914.1\|503659_505093_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.1e-103	50.5
WP_025760278.1\|505167_505419_-	hypothetical protein	NA	NA	NA	NA
WP_004115414.1\|505904_507380_+	UvrD-helicase domain-containing protein	A0A075DXT4	Acinetobacter_phage	2.6e-47	31.5
WP_004115412.1\|507446_509066_+	TraI domain-containing protein	NA	NA	NA	NA
WP_004115409.1\|509125_510157_+\|integrase	site-specific integrase	NA	NA	NA	NA
516023:516037	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1294799 : 1338540

Escherichia_phage(51.72%)

holin,transposase,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025756107.1\|1294799_1295000_-	hypothetical protein	G8C7S1	Escherichia_phage	1.5e-27	86.4
WP_025756106.1\|1295191_1295464_-	hypothetical protein	NA	NA	NA	NA
WP_032103556.1\|1295473_1295713_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	2.8e-28	74.4
WP_088244094.1\|1295690_1296059_-	DUF2591 family protein	G9L6B5	Escherichia_phage	3.8e-32	56.4
WP_025760427.1\|1296058_1296277_-	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	2.7e-17	60.6
WP_025760425.1\|1296616_1296865_-	hypothetical protein	NA	NA	NA	NA
WP_131820573.1\|1296861_1297062_-	hypothetical protein	NA	NA	NA	NA
WP_025760424.1\|1297058_1297277_-	hypothetical protein	NA	NA	NA	NA
WP_025760423.1\|1297279_1298032_-	hypothetical protein	M1FN76	Enterobacteria_phage	8.4e-127	84.0
WP_025760422.1\|1298045_1298522_-	HNH endonuclease	A8B107	Xanthomonas_virus	1.9e-31	45.3
WP_025760421.1\|1298518_1298671_-	DUF1317 family protein	T1SAR0	Salmonella_phage	1.5e-06	46.2
WP_071684200.1\|1298667_1299096_-	regulator	M9NYX4	Enterobacteria_phage	4.0e-73	96.5
WP_025760411.1\|1299092_1299710_-	YqaJ viral recombinase family protein	A0A0S2SY31	Pseudomonas_phage	1.2e-57	56.4
WP_088244095.1\|1299706_1300453_-	phage recombination protein Bet	A0A0M4RD39	Salmonella_phage	2.0e-64	65.3
WP_025760409.1\|1300471_1300756_-	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	2.2e-48	95.7
WP_025760408.1\|1300763_1301738_-	hypothetical protein	A0A077KCC0	Edwardsiella_phage	5.2e-36	71.8
WP_006809788.1\|1301808_1302018_-	cell division protein FtsZ	M9NZE2	Enterobacteria_phage	6.7e-34	95.7
WP_023330205.1\|1302014_1302173_-	hypothetical protein	G8C7T3	Escherichia_phage	1.1e-20	92.3
WP_025760126.1\|1302169_1302493_-	hypothetical protein	NA	NA	NA	NA
WP_025760125.1\|1303314_1303512_+	hypothetical protein	G8C7T7	Escherichia_phage	4.1e-25	96.9
WP_023294194.1\|1303805_1304168_-	hypothetical protein	A0A1P8DTD0	Proteus_phage	1.1e-18	49.5
WP_016042178.1\|1304401_1305091_-	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	2.2e-126	100.0
WP_016042179.1\|1305201_1305429_+	helix-turn-helix domain-containing protein	G8C7U2	Escherichia_phage	4.1e-37	100.0
WP_025759375.1\|1305458_1306004_+	toxin YdaT domain-containing protein	G8C7U3	Escherichia_phage	3.1e-78	81.2
WP_015571544.1\|1306087_1306234_+	hypothetical protein	NA	NA	NA	NA
WP_025759377.1\|1306226_1307123_+	hypothetical protein	F1C5C3	Cronobacter_phage	2.6e-98	60.1
WP_025759378.1\|1307112_1308546_+	AAA family ATPase	Q716D2	Shigella_phage	2.8e-235	85.4
WP_025759380.1\|1308886_1309366_+	hypothetical protein	A0A193GYL1	Enterobacter_phage	1.6e-06	30.6
WP_071994071.1\|1309362_1309587_+	Lar family restriction alleviation protein	NA	NA	NA	NA
WP_025759382.1\|1309583_1310015_+	ead/Ea22-like family protein	K7P6V8	Enterobacteria_phage	2.6e-11	50.0
WP_025759383.1\|1310019_1310706_+	hypothetical protein	M9NZE4	Enterobacteria_phage	5.1e-30	41.0
WP_025759385.1\|1311209_1311641_+	recombination protein NinB	A0A2H4FNF5	Salmonella_phage	1.3e-26	42.9
WP_025759387.1\|1311633_1312215_+	HNH endonuclease	A0A2H4PQR4	Staphylococcus_phage	2.4e-20	43.4
WP_032672628.1\|1312214_1312385_+	NinE family protein	G8C7V4	Escherichia_phage	1.3e-22	91.1
WP_025759388.1\|1312377_1312989_+	recombination protein NinG	A0A0M4RU10	Salmonella_phage	2.9e-40	53.7
WP_025759389.1\|1312985_1313186_+	hypothetical protein	NA	NA	NA	NA
WP_032665720.1\|1313285_1313675_+	antitermination protein	A0A088CD47	Shigella_phage	5.6e-42	65.3
WP_025759393.1\|1313704_1314064_-	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	8.9e-18	48.7
WP_162876077.1\|1314163_1314325_+	hypothetical protein	A0A077KAX5	Edwardsiella_phage	3.4e-17	79.2
WP_001531258.1\|1314675_1315458_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	6.1e-136	96.5
WP_000627495.1\|1315454_1316477_-\|transposase	IS21-like element ISSen3 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-174	85.3
WP_025759395.1\|1317631_1317955_+\|holin	phage holin, lambda family	Q5G8R5	Enterobacteria_phage	5.7e-40	76.4
WP_088244097.1\|1317935_1318379_+	lysozyme	A0A0M4R365	Salmonella_phage	1.5e-59	80.5
WP_025759397.1\|1318378_1318924_+	hypothetical protein	K7PHH7	Enterobacteria_phage	3.8e-52	69.4
WP_025759398.1\|1319129_1319348_+	hypothetical protein	NA	NA	NA	NA
WP_025759400.1\|1319513_1320164_+	hypothetical protein	G8C7P2	Escherichia_phage	4.6e-113	98.6
WP_025759401.1\|1320160_1321732_+\|terminase	terminase	G8C7P3	Escherichia_phage	0.0e+00	97.7
WP_025759403.1\|1321736_1323140_+	DUF4055 domain-containing protein	G8C7P4	Escherichia_phage	1.6e-259	97.8
WP_025759405.1\|1323141_1324245_+	hypothetical protein	G8C7P5	Escherichia_phage	7.1e-191	92.1
WP_152001947.1\|1324345_1324555_+	hypothetical protein	NA	NA	NA	NA
WP_025759408.1\|1324728_1325481_+	hypothetical protein	G8C7P6	Escherichia_phage	1.7e-119	89.2
WP_025759409.1\|1325498_1326638_+	hypothetical protein	G8C7P7	Escherichia_phage	5.3e-173	83.5
WP_025759411.1\|1326677_1326878_+	hypothetical protein	G8C7P8	Escherichia_phage	1.3e-21	83.3
WP_025759412.1\|1326880_1327246_+	hypothetical protein	R9TRJ4	Aeromonas_phage	1.8e-45	77.5
WP_088244098.1\|1327259_1327742_+	hypothetical protein	G8C7P9	Escherichia_phage	2.3e-77	87.5
WP_025759416.1\|1327743_1328097_+	hypothetical protein	G8C7Q0	Escherichia_phage	3.4e-54	94.0
WP_025759417.1\|1328098_1328698_+	hypothetical protein	G8C7Q1	Escherichia_phage	3.1e-100	90.5
WP_025759418.1\|1328687_1329134_+	DUF4128 domain-containing protein	G8C7Q2	Escherichia_phage	5.1e-71	90.6
WP_088244099.1\|1329180_1330113_+\|tail	phage tail protein	G8C7Q3	Escherichia_phage	4.8e-164	97.1
WP_016247125.1\|1330178_1330517_+	hypothetical protein	G8C7Q5	Escherichia_phage	2.1e-53	92.9
WP_025759422.1\|1330534_1330822_+	DUF1799 domain-containing protein	I6PD79	Cronobacter_phage	9.3e-18	61.5
WP_088244100.1\|1330821_1334052_+\|tail	phage tail tape measure protein	G8C7Q6	Escherichia_phage	1.4e-191	43.3
WP_192869214.1\|1334125_1334536_+	hypothetical protein	A0A0M4QWT0	Salmonella_phage	4.6e-26	47.0
WP_023277161.1\|1334543_1334840_+	hypothetical protein	A0A2I7RH26	Vibrio_phage	4.9e-06	44.1
WP_025759425.1\|1335321_1335501_+	hypothetical protein	NA	NA	NA	NA
WP_016247130.1\|1335511_1336009_+	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_025759426.1\|1336088_1336439_+\|tail	phage tail protein	G8C7R0	Escherichia_phage	3.0e-58	99.1
WP_025759427.1\|1336438_1337209_+\|tail	phage minor tail protein L	G8C7R1	Escherichia_phage	1.2e-141	93.4
WP_025759428.1\|1337221_1337953_+	C40 family peptidase	G8C7R2	Escherichia_phage	2.8e-151	98.4
WP_016042151.1\|1337940_1338540_+\|tail	tail assembly protein	G8C7R3	Escherichia_phage	5.5e-105	100.0

DBSCAN-SWA_3

1342879 : 1347571

Enterobacteria_phage(33.33%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_161493418.1\|1342879_1344052_+\|tail	tail fiber domain-containing protein	K7P6M1	Enterobacteria_phage	8.2e-44	51.7
WP_025759349.1\|1344141_1344405_-	DinI family protein	K7PKM2	Enterobacterial_phage	1.1e-38	94.3
WP_025759348.1\|1344491_1344731_+	hypothetical protein	K7P7N3	Enterobacteria_phage	1.7e-33	83.3
WP_025759347.1\|1344730_1345051_+	hypothetical protein	K7PGV5	Enterobacterial_phage	4.1e-22	50.0
WP_088244101.1\|1345050_1346316_+	Y-family DNA polymerase	I6RSM4	Salmonella_phage	2.7e-210	85.1
WP_045286113.1\|1346659_1347571_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	1.3e-07	33.3

DBSCAN-SWA_4

2058122 : 2115783

Enterobacterial_phage(35.42%)

integrase,holin,transposase,terminase,portal,tail,tRNA,protease

attL 2052348:2052365|attR 2111525:2111542

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2052348:2052365	attL	NA	NA	NA	NA
WP_025758181.1\|2058122_2059235_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_025758182.1\|2059275_2059749_-	NUDIX hydrolase	NA	NA	NA	NA
WP_025758184.1\|2059758_2060412_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_025758185.1\|2060529_2061780_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	7.9e-21	94.4
WP_025758186.1\|2061857_2062205_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_025758188.1\|2062279_2062525_+	DUF2543 family protein	NA	NA	NA	NA
WP_025758189.1\|2062595_2064104_-	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
WP_032672531.1\|2064339_2065410_+	EAL domain-containing protein	NA	NA	NA	NA
WP_025758193.1\|2065588_2067061_+	GGDEF domain-containing protein	G3MA91	Bacillus_virus	1.7e-14	28.4
WP_008500746.1\|2067343_2067592_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_014883431.1\|2067721_2067820_-	YoaK family small membrane protein	NA	NA	NA	NA
WP_025758194.1\|2067865_2068894_-	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	1.6e-14	33.2
WP_025758195.1\|2069202_2069457_+	DUF333 domain-containing protein	NA	NA	NA	NA
WP_025758196.1\|2069537_2069843_+	hypothetical protein	NA	NA	NA	NA
WP_025758197.1\|2069843_2070188_-	DUF488 domain-containing protein	NA	NA	NA	NA
WP_025758199.1\|2070289_2070997_+	CTP synthase	NA	NA	NA	NA
WP_025758200.1\|2071028_2072216_-	CynX/NimT family MFS transporter	NA	NA	NA	NA
WP_170940845.1\|2072312_2073107_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_008500737.1\|2073090_2073537_-	DUF441 domain-containing protein	NA	NA	NA	NA
WP_010430055.1\|2073681_2073786_+	hypothetical protein	NA	NA	NA	NA
WP_025758202.1\|2073807_2074308_-\|tRNA	YbaK/prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_088244167.1\|2074570_2075713_-\|integrase	phage integrase Arm DNA-binding domain-containing protein	O21929	Phage_21	7.9e-92	48.1
WP_008500733.1\|2075687_2075951_-	hypothetical protein	NA	NA	NA	NA
WP_025758204.1\|2075983_2076253_-	hypothetical protein	K7PKM4	Enterobacterial_phage	1.9e-36	83.1
WP_025758206.1\|2076319_2076574_-	hypothetical protein	A0A1B0V7L5	Salmonella_phage	9.1e-09	47.4
WP_192869220.1\|2076573_2077209_-	DUF551 domain-containing protein	A0A2H4FNA9	Salmonella_phage	1.5e-12	44.3
WP_025758209.1\|2077384_2078407_-	chromosome partitioning protein ParB	K7PKM7	Enterobacterial_phage	2.9e-170	91.9
WP_025758210.1\|2078406_2078820_-	hypothetical protein	K7PJS4	Enterobacterial_phage	6.8e-62	92.0
WP_025758212.1\|2078868_2079189_-	hypothetical protein	K7P7N6	Enterobacteria_phage	4.7e-26	55.7
WP_032645236.1\|2079975_2080695_-	LexA family transcriptional regulator	A0A2R2X2B0	Escherichia_phage	3.1e-78	62.9
WP_063409901.1\|2080793_2081012_+	hypothetical protein	A0A2K8HL98	Pseudomonas_phage	4.9e-11	60.3
WP_023337115.1\|2081053_2081524_+	hypothetical protein	K7PJS5	Enterobacterial_phage	1.8e-79	98.7
WP_071788893.1\|2081764_2081977_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	1.5e-12	65.4
WP_025760121.1\|2081933_2082875_+	conserved phage C-terminal domain-containing protein	H2DE83	Erwinia_phage	3.2e-30	59.6
WP_088244168.1\|2082871_2083366_+	hypothetical protein	NA	NA	NA	NA
WP_025760119.1\|2083365_2084118_+	hypothetical protein	M1FN76	Enterobacteria_phage	4.0e-129	85.2
WP_025760118.1\|2084131_2084791_+	DNA methyltransferase	I6PDF5	Cronobacter_phage	7.7e-100	79.5
WP_025760117.1\|2084787_2085015_+	hypothetical protein	NA	NA	NA	NA
WP_025760116.1\|2085011_2085332_+	LexA family transcriptional regulator	K7PHB4	Enterobacterial_phage	7.9e-42	78.3
WP_025760115.1\|2085328_2085736_+	RusA family crossover junction endodeoxyribonuclease	A0A1C9IIA0	Salmonella_phage	5.5e-56	84.3
WP_023330784.1\|2085806_2086601_+	KilA-N domain-containing protein	Q8HA92	Salmonella_phage	1.1e-92	61.4
WP_025760114.1\|2086608_2087598_+	DUF968 domain-containing protein	K7PJS6	Enterobacterial_phage	2.5e-187	94.8
WP_025760113.1\|2087611_2088190_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	5.1e-47	53.9
WP_025760111.1\|2088303_2088882_+	hypothetical protein	NA	NA	NA	NA
WP_022648767.1\|2088989_2089385_+\|holin	phage holin family protein	K7PHB9	Enterobacterial_phage	9.1e-64	99.2
WP_022648766.1\|2089371_2089653_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	4.1e-42	93.5
WP_088244169.1\|2089652_2090279_+	glycoside hydrolase family 19 protein	K7PJS7	Enterobacterial_phage	1.0e-109	93.3
WP_025760109.1\|2090286_2090556_+	hypothetical protein	K7PGW4	Enterobacterial_phage	5.0e-05	87.4
WP_025760108.1\|2090565_2091186_+	hypothetical protein	A0A1B0VMI8	Pseudomonas_phage	9.6e-44	42.7
WP_050597170.1\|2091205_2091418_+	hypothetical protein	K7PM01	Enterobacterial_phage	8.1e-19	86.0
WP_014839937.1\|2091494_2092463_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	2.6e-181	97.2
WP_025760468.1\|2092548_2092824_+	hypothetical protein	NA	NA	NA	NA
WP_088244170.1\|2093302_2094178_+	hypothetical protein	NA	NA	NA	NA
WP_025759369.1\|2095203_2095692_+	DUF1441 family protein	K7PJY2	Enterobacterial_phage	8.3e-75	91.4
WP_088244171.1\|2095691_2097794_+\|terminase	phage terminase large subunit family protein	K7PH52	Enterobacterial_phage	0.0e+00	97.6
WP_025759367.1\|2097790_2098006_+	hypothetical protein	K7PMB5	Enterobacterial_phage	7.2e-31	97.2
WP_088244172.1\|2098002_2099502_+\|portal	phage portal protein	K7PHM5	Enterobacterial_phage	2.2e-288	99.8
WP_192869217.1\|2099428_2101462_+\|protease	ATP-dependent Clp protease proteolytic subunit	K7PKX4	Enterobacterial_phage	0.0e+00	96.3
WP_025759364.1\|2101544_2101871_+	DUF2190 family protein	K7PJY3	Enterobacterial_phage	6.8e-49	93.5
WP_025759363.1\|2101863_2102139_+	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	5.2e-26	63.7
WP_013096336.1\|2102147_2102702_+\|tail	phage tail protein	K7P7A8	Enterobacteria_phage	3.5e-69	84.7
WP_013096337.1\|2102698_2103097_+\|tail	tail protein	S5MW30	Escherichia_phage	2.5e-45	64.4
WP_025759362.1\|2103104_2103842_+\|tail	phage tail protein	O64327	Escherichia_phage	1.2e-128	96.7
WP_016063411.1\|2103880_2104303_+\|tail	phage minor tail protein G	K7P7M5	Enterobacteria_phage	2.6e-56	100.0
WP_016063412.1\|2104311_2104632_+\|tail	phage tail assembly protein T	K7P6V0	Enterobacteria_phage	2.5e-56	100.0
WP_025759359.1\|2104609_2107126_+\|tail	phage tail tape measure protein	K7PKR0	Enterobacteria_phage	0.0e+00	90.5
WP_025759358.1\|2107131_2107479_+\|tail	phage tail protein	K7PJT2	Enterobacteria_phage	7.0e-60	99.1
WP_025759357.1\|2107475_2108231_+\|tail	phage minor tail protein L	K7PGX3	Enterobacteria_phage	5.1e-148	99.6
WP_025759356.1\|2108232_2108943_+	C40 family peptidase	K7PGR2	Enterobacteria_phage	3.9e-142	96.2
WP_053263847.1\|2109030_2109426_+	hypothetical protein	NA	NA	NA	NA
WP_025759354.1\|2109487_2110075_+\|tail	tail assembly protein	K7P6V1	Enterobacteria_phage	5.1e-95	94.8
WP_001324901.1\|2110071_2110338_+	hypothetical protein	K7P7B0	Enterobacteria_phage	7.7e-43	98.9
WP_161493418.1\|2114610_2115783_+\|tail	tail fiber domain-containing protein	K7P6M1	Enterobacteria_phage	8.2e-44	51.7
2111525:2111542	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2682415 : 2736190

Escherichia_phage(13.33%)

integrase,transposase

attL 2726623:2726682|attR 2732286:2733106

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001339197.1\|2682415_2683624_+\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0
WP_025758878.1\|2683710_2684151_+	GFA family protein	NA	NA	NA	NA
WP_025758879.1\|2684140_2685085_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.7e-12	26.1
WP_025758880.1\|2685255_2686206_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_025758881.1\|2686214_2687321_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_025758882.1\|2687317_2688085_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-15	26.3
WP_025758883.1\|2688077_2688797_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-11	25.8
WP_025758885.1\|2688825_2689983_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_025758886.1\|2690000_2690483_+	L-2-amino-thiazoline-4-carboxylic acid hydrolase	NA	NA	NA	NA
WP_025758887.1\|2690479_2691706_+	Zn-dependent hydrolase	NA	NA	NA	NA
WP_025758888.1\|2691776_2693264_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	2.2e-33	31.2
WP_025758889.1\|2693380_2693956_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_025758890.1\|2694098_2694548_-	hypothetical protein	NA	NA	NA	NA
WP_025758891.1\|2694618_2696058_-	anion permease	NA	NA	NA	NA
WP_025758892.1\|2696155_2698750_-	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_025758893.1\|2698767_2699316_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_025758894.1\|2699333_2700209_-	triphosphoribosyl-dephospho-CoA synthase CitG	NA	NA	NA	NA
WP_025758895.1\|2700183_2700723_-	citrate lyase holo-[acyl-carrier protein] synthase	NA	NA	NA	NA
WP_025758896.1\|2700728_2702249_-	citrate lyase subunit alpha	NA	NA	NA	NA
WP_025758897.1\|2702280_2703156_-	citrate (pro-3S)-lyase subunit beta	NA	NA	NA	NA
WP_047958684.1\|2703155_2703446_-	citrate lyase acyl carrier protein	NA	NA	NA	NA
WP_025758900.1\|2703470_2704538_-	[citrate (pro-3S)-lyase] ligase	NA	NA	NA	NA
WP_025758902.1\|2704556_2705420_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_025758903.1\|2705491_2706736_-	MFS transporter	NA	NA	NA	NA
WP_032672573.1\|2706804_2707893_-	4-oxalomesaconate tautomerase	NA	NA	NA	NA
WP_025758906.1\|2708047_2708977_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_080276776.1\|2709051_2709801_+	cysteine hydrolase	NA	NA	NA	NA
WP_025758909.1\|2709862_2710816_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_025758911.1\|2710825_2711662_-	N-hydroxyarylamine O-acetyltransferase	NA	NA	NA	NA
WP_025758912.1\|2711770_2712343_+	flavin reductase family protein	NA	NA	NA	NA
WP_025760190.1\|2712603_2713029_+	DUF3828 domain-containing protein	NA	NA	NA	NA
WP_025760191.1\|2713101_2715201_-	elongation factor G	A0A1S5SF82	Streptococcus_phage	3.1e-62	26.6
WP_025760192.1\|2715361_2715661_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_025760193.1\|2715703_2715940_-	tautomerase family protein	NA	NA	NA	NA
WP_025760194.1\|2716001_2716463_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_025760195.1\|2716497_2717823_-	2-hydroxycarboxylate transporter family protein	A0A140XAH4	Dickeya_phage	9.6e-25	56.5
WP_025760196.1\|2718239_2719925_+	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_025760197.1\|2719969_2720971_-	LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferasee	A0A1W6JP29	Morganella_phage	2.6e-54	41.1
WP_025760198.1\|2721149_2721380_-	tautomerase PptA	NA	NA	NA	NA
WP_025760199.1\|2721417_2722035_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_025760200.1\|2722076_2722964_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000480968.1\|2723133_2723970_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001082319.1\|2723969_2724773_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	Q75ZG1	Hepacivirus	4.9e-24	34.3
WP_085959879.1\|2724879_2726009_-\|transposase	IS3-like element IS1133 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.6e-52	41.1
WP_011013294.1\|2726073_2726619_-	recombinase family protein	E5FFF9	Burkholderia_phage	6.9e-30	46.7
2726623:2726682	attL	NA	NA	NA	NA
WP_001067855.1\|2726674_2727379_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001038045.1\|2729309_2729969_-	tetracycline resistance transcriptional repressor TetR(C)	NA	NA	NA	NA
WP_000841446.1\|2730061_2731252_+	tetracycline efflux MFS transporter Tet(C)	A0A2H4UVM2	Bodo_saltans_virus	8.1e-07	24.0
WP_002310911.1\|2731155_2731494_+	hypothetical protein	NA	NA	NA	NA
WP_071533317.1\|2731490_2731676_-	hypothetical protein	NA	NA	NA	NA
WP_000015696.1\|2731701_2731980_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001067855.1\|2732337_2733042_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001138082.1\|2733304_2736190_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-190	39.9
2732286:2733106	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3409977 : 3417722

Bodo_saltans_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025759316.1\|3409977_3410589_+	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	A0A2H4UVM0	Bodo_saltans_virus	3.5e-14	29.3
WP_025759317.1\|3410629_3411610_-	LPS O-antigen chain length determinant protein WzzB	NA	NA	NA	NA
WP_025759318.1\|3411803_3412808_+	NAD-dependent epimerase	A0A2K9L0I7	Tupanvirus	1.7e-34	29.9
WP_025759319.1\|3412859_3414026_-	UDP-glucose 6-dehydrogenase	A0A1J0FA55	Only_Syngen_Nebraska_virus	1.4e-112	54.2
WP_025759321.1\|3414254_3415136_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.8e-105	63.4
WP_088244288.1\|3415135_3416221_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	5.0e-96	51.2
WP_025759323.1\|3416315_3417722_-	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	4.0e-37	28.3

DBSCAN-SWA_7

4290579 : 4347578

uncultured_Caudovirales_phage(16.67%)

integrase,transposase

attL 4328050:4328065|attR 4354838:4354853

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088244370.1\|4290579_4291734_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_014171606.1\|4291896_4292385_-	TIGR00645 family protein	NA	NA	NA	NA
WP_025758470.1\|4292466_4292970_-	hypothetical protein	NA	NA	NA	NA
WP_025758471.1\|4293073_4293478_+	hypothetical protein	NA	NA	NA	NA
WP_025758472.1\|4293479_4293926_+	hypothetical protein	NA	NA	NA	NA
WP_025758473.1\|4293922_4295374_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.3e-10	25.4
WP_025758475.1\|4295648_4296074_-	TonB system transport protein ExbD	NA	NA	NA	NA
WP_025758477.1\|4296078_4296810_-	tol-pal system-associated acyl-CoA thioesterase	NA	NA	NA	NA
WP_025758478.1\|4297061_4298249_+	cystathionine beta-lyase	NA	NA	NA	NA
WP_025758479.1\|4298392_4299052_+	DedA family protein	NA	NA	NA	NA
WP_025758480.1\|4299097_4299997_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_025758481.1\|4300192_4301356_+	alcohol dehydrogenase	NA	NA	NA	NA
WP_025758482.1\|4301461_4302289_+	2,5-didehydrogluconate reductase DkgA	A0A2H4PQR8	Staphylococcus_phage	8.6e-64	45.6
WP_025758484.1\|4302330_4302732_-	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_000140246.1\|4303966_4304296_-	hypothetical protein	NA	NA	NA	NA
WP_021242119.1\|4304500_4307776_-	hypothetical protein	NA	NA	NA	NA
WP_017384073.1\|4308634_4308931_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_017384071.1\|4310278_4310554_+	formaldehyde-responsive transcriptional repressor FrmR	NA	NA	NA	NA
WP_017384070.1\|4310588_4311698_+	S-(hydroxymethyl)glutathione dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	2.2e-30	28.7
WP_012561111.1\|4311741_4312140_+	VOC family protein	NA	NA	NA	NA
WP_012561110.1\|4312204_4313041_+	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_000227969.1\|4313628_4314705_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_016151369.1\|4316244_4316595_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	9.6e-41	65.5
WP_022649395.1\|4318758_4319727_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	6.9e-182	96.9
WP_007896426.1\|4319880_4321206_+	pyridine nucleotide-disulfide oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	6.5e-114	48.1
WP_016151347.1\|4322449_4322971_+	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_023304425.1\|4322967_4323921_+	fec operon regulator FecR	NA	NA	NA	NA
WP_022652364.1\|4324007_4326332_+	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_007898890.1\|4326376_4327279_+	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_004118243.1\|4327275_4328274_+	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
4328050:4328065	attL	NA	NA	NA	NA
WP_004118246.1\|4328270_4329227_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	5.3e-17	26.1
WP_004152282.1\|4329227_4329995_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	9.8e-14	25.2
WP_007898888.1\|4330093_4330387_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	4.7e-49	95.9
WP_007898884.1\|4330717_4330996_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000427619.1\|4331257_4332262_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_088244373.1\|4332669_4333752_+	DNA-binding transcriptional repressor LacI	C6ZCU4	Enterobacteria_phage	1.9e-188	97.8
WP_007894989.1\|4333873_4336948_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.8
WP_003846917.1\|4336999_4338253_+	lactose permease	NA	NA	NA	NA
WP_017384068.1\|4339334_4340468_-	glutathione-independent formaldehyde dehydrogenase	NA	NA	NA	NA
WP_085949497.1\|4340802_4341950_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.3e-147	92.6
WP_017384060.1\|4342040_4342469_-	hypothetical protein	NA	NA	NA	NA
WP_017384059.1\|4342472_4344590_-	hypothetical protein	NA	NA	NA	NA
WP_007897920.1\|4344577_4346344_-	hypothetical protein	NA	NA	NA	NA
WP_007897923.1\|4346330_4347578_-\|integrase	site-specific integrase	NA	NA	NA	NA
4354838:4354853	attR	NA	NA	NA	NA

DBSCAN-SWA_8

4409388 : 4414651

Erwinia_phage(55.56%)

integrase

attL 4405138:4405152|attR 4416479:4416493

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4405138:4405152	attL	NA	NA	NA	NA
WP_088244381.1\|4409388_4409838_-	phage virion morphogenesis protein	O80313	Escherichia_phage	4.2e-49	69.4
WP_032672752.1\|4410423_4410813_-	protein lysB	O80310	Escherichia_phage	9.6e-34	60.5
WP_025760356.1\|4410809_4411262_-	lysozyme	A0A218M4K3	Erwinia_phage	2.6e-67	81.8
WP_025760355.1\|4411302_4411524_-	hypothetical protein	A0A218M4L5	Erwinia_phage	3.0e-24	72.6
WP_071994095.1\|4411918_4412119_-	DUF2724 domain-containing protein	Q6K1F7	Salmonella_virus	1.1e-30	92.4
WP_025760353.1\|4412126_4412636_-	phage regulatory CII family protein	A0A0M4QWN1	Salmonella_phage	3.0e-83	91.7
WP_025760352.1\|4412645_4412930_-	hypothetical protein	A0A218M4I5	Erwinia_phage	1.3e-40	92.0
WP_025760351.1\|4413065_4413653_+	phage repressor protein CI	A0A218M4J1	Erwinia_phage	7.7e-59	57.7
WP_088244382.1\|4413652_4414651_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	7.7e-176	89.4
4416479:4416493	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP021851

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection