CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP021952	Klebsiella pneumoniae strain AR_0148 plasmid tig00000169_pilon, complete sequence	0 crisprs	DEDDh	0	1
NZ_CP021953	Klebsiella pneumoniae strain AR_0148 plasmid tig00000185_pilon, complete sequence	0 crisprs	RT	0	1
NZ_CP021950	Klebsiella pneumoniae strain AR_0148 chromosome, complete genome	2 crisprs	cas3,RT,csa3,DinG,WYL,DEDDh	1	8
NZ_CP021951	Klebsiella pneumoniae strain AR_0148 plasmid tig00000168_pilon, complete sequence	0 crisprs	cas3,csa3,RT	0	1
NZ_CP021954	Klebsiella pneumoniae strain AR_0148 plasmid tig00001025alt_u_pilon, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

9686 : 55355

Escherichia_phage(25.0%)

transposase,integrase

attL 15444:15459|attR 32906:32921

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000080200.1\|9686_11300_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.8e-182	63.6
WP_000624722.1\|11330_11681_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|11677_12103_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000714163.1\|12284_12506_+	hypothetical protein	NA	NA	NA	NA
WP_000427620.1\|12687_13692_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_001138073.1\|13770_16743_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
15444:15459	attL	NA	NA	NA	NA
WP_001162012.1\|16745_17303_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
WP_000845039.1\|17608_18622_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_032488579.1\|18852_19407_+	aminoglycoside N-acetyltransferase AAC(6')-Ib3	NA	NA	NA	NA
WP_000679427.1\|19575_19923_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|19916_20756_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000376617.1\|20882_21125_+	hypothetical protein	NA	NA	NA	NA
WP_001183923.1\|21208_21508_-	DUF2293 domain-containing protein	NA	NA	NA	NA
WP_016479969.1\|21621_21792_-	hypothetical protein	NA	NA	NA	NA
WP_004201046.1\|23018_23672_+	endonuclease III	NA	NA	NA	NA
WP_072277680.1\|23822_26840_-\|transposase	Tn3-like element IS3000 family transposase	A0A125RQ78	Bacillus_phage	3.2e-52	24.7
WP_004151610.1\|28464_29367_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	7.7e-159	99.3
WP_002210513.1\|29627_30389_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004176269.1\|30409_31270_-	class A broad-spectrum beta-lactamase SHV-11	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_020324562.1\|32153_32858_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.9e-138	99.6
WP_072199448.1\|33348_33768_+	AAA family ATPase	NA	NA	NA	NA
32906:32921	attR	NA	NA	NA	NA
WP_000080860.1\|35853_36990_-	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_001330846.1\|37040_37286_-	hypothetical protein	NA	NA	NA	NA
WP_000951934.1\|37291_37483_+	hypothetical protein	NA	NA	NA	NA
WP_000587837.1\|37964_38507_-	AAA family ATPase	NA	NA	NA	NA
WP_000557454.1\|38519_39380_-	aminoglycoside N-acetyltransferase AAC(3)-IId	NA	NA	NA	NA
WP_085940656.1\|39512_40657_-\|transposase	IS3-like element ISAba14 family transposase	S5WIU1	Leptospira_phage	2.3e-14	28.1
WP_019768104.1\|40707_41190_+	hypothetical protein	NA	NA	NA	NA
WP_087776199.1\|41525_42732_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.6e-101	62.7
WP_000050481.1\|43250_44792_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000259031.1\|45196_46036_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_052238321.1\|46029_46365_-	ethidium bromide resistance protein	NA	NA	NA	NA
WP_025999322.1\|46257_46623_+	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_004193231.1\|46626_47502_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_015058923.1\|48328_48988_-	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
WP_004201167.1\|48992_49358_-	bleomycin binding protein Ble-MBL	NA	NA	NA	NA
WP_004201164.1\|49361_50174_-	subclass B1 metallo-beta-lactamase NDM-1	NA	NA	NA	NA
WP_000855769.1\|51321_52167_+	RmtC family 16S rRNA (guanine(1405)-N(7))-methyltransferase	NA	NA	NA	NA
WP_004199413.1\|52337_55355_+\|transposase	Tn3-like element IS3000 family transposase	A0A125RQ78	Bacillus_phage	5.5e-52	24.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP021953

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3515 : 59608

Escherichia_phage(25.0%)

transposase,integrase

attL 42131:42190|attR 65291:66112

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000015958.1\|3515_4292_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	6.4e-53	92.9
WP_000764642.1\|4349_4607_-	hypothetical protein	NA	NA	NA	NA
WP_004118283.1\|5374_6241_+	replication initiation protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
WP_000339857.1\|6597_6867_-	hypothetical protein	NA	NA	NA	NA
WP_000368714.1\|7281_8487_+	ParA family protein	A0A077SL49	Escherichia_phage	2.4e-163	69.6
WP_012600007.1\|8483_9461_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	2.6e-88	54.4
WP_004118291.1\|9542_10814_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	4.9e-151	63.3
WP_000776034.1\|10813_11245_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.6e-29	53.3
WP_004152765.1\|11653_13138_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_001776122.1\|13607_14573_+	DUF1738 domain-containing protein	A0A1V0EEV1	Caulobacter_phage	1.6e-58	42.7
WP_001776120.1\|15052_15484_+	hypothetical protein	NA	NA	NA	NA
WP_001776119.1\|15516_16044_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.7e-21	39.5
WP_001166628.1\|16303_16759_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_004200999.1\|16830_17196_+	mercuric ion transporter MerT	NA	NA	NA	NA
WP_000732275.1\|17211_17487_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_000522996.1\|17514_17940_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000209296.1\|17978_19664_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_001277466.1\|19681_20047_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_001087807.1\|20043_20280_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001446012.1\|20263_20383_-	hypothetical protein	NA	NA	NA	NA
WP_000993245.1\|20345_20558_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_003124096.1\|20688_21249_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	2.1e-50	88.6
WP_001138070.1\|21251_24218_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
WP_000427619.1\|24296_25301_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_000954592.1\|25482_25659_-	DUF4102 domain-containing protein	T1S9J3	Salmonella_phage	1.0e-06	68.6
WP_001043260.1\|25988_26804_+	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
WP_001082319.1\|26864_27668_+	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_000480968.1\|27667_28504_+	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001120891.1\|28475_29015_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000027057.1\|29224_30085_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|30267_30825_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000608644.1\|31388_32651_+\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_000239590.1\|32906_33782_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
WP_001393253.1\|33828_34161_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
WP_001097412.1\|39152_39716_-	hypothetical protein	NA	NA	NA	NA
WP_001348195.1\|39739_40114_-	cupin domain-containing protein	NA	NA	NA	NA
WP_001515734.1\|40178_40742_-\|transposase	transposase	NA	NA	NA	NA
WP_000046891.1\|40984_41320_+	thermonuclease family protein	G8DH70	Emiliania_huxleyi_virus	2.8e-05	35.7
42131:42190	attL	NA	NA	NA	NA
WP_020324562.1\|42193_42898_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.9e-138	99.6
WP_002063889.1\|44091_44634_-	AAA family ATPase	NA	NA	NA	NA
WP_000557452.1\|44646_45507_-	aminoglycoside N-acetyltransferase AAC(3)-IIa	NA	NA	NA	NA
WP_001067855.1\|45613_46318_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001334766.1\|46949_47780_-	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_063840321.1\|47910_48465_-	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
WP_020324562.1\|48608_49313_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.9e-138	99.6
WP_071549088.1\|49337_49850_+	restriction endonuclease	NA	NA	NA	NA
WP_001749967.1\|49854_50061_+	hypothetical protein	NA	NA	NA	NA
WP_001288432.1\|50442_51876_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	7.0e-106	50.6
WP_001389365.1\|53383_54148_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001144737.1\|54290_54557_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_004201280.1\|54777_55251_-	trimethoprim-resistant dihydrofolate reductase DfrA14	G3MBI7	Bacillus_virus	8.4e-16	28.9
WP_000845048.1\|55406_56420_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001749988.1\|56812_57382_+	recombinase family protein	E5FFF9	Burkholderia_phage	5.2e-36	43.2
WP_004201235.1\|58138_59608_+	HNH endonuclease	G0X580	Salmonella_phage	5.5e-21	51.3
65291:66112	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP021950

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021950_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021950_1

2008684-2008779

Orphan

Consensus_repeat	Method
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021950_1

>merge|NZ_CP021950|1|2008684-2008779|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAACCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGTTGGCACTTTGTTGGCATTCTGTTGGCACAA

>NZ_CP021950|1|1|2008684-2008779|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGT
TGGCACTTTGTTGGCATTCTGTTGGCACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021950.1\|WP_004151303.1\|2011375_2011570_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021950.1\|WP_004151306.1\|2012800_2013481_+\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NZ_CP021950.1\|WP_004151288.1\|2003332_2003788_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182057
NZ_CP021950.1\|WP_004151305.1\|2011958_2012804_+\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871
NZ_CP021950.1\|WP_004151287.1\|2003162_2003333_-\|NinE-family-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP021950.1\|WP_004151296.1\|2006853_2008284_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672
NZ_CP021950.1\|WP_004151295.1\|2006560_2006854_-\|protein-ren	unknown	unknown	gnl\|CDD\|238042
NZ_CP021950.1\|WP_004151299.1\|2009659_2009893_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NZ_CP021950.1\|WP_004151293.1\|2005108_2005951_-\|translation-repressor-RelE	unknown	unknown	gnl\|CDD\|379401
NZ_CP021950.1\|WP_004151294.1\|2006057_2006564_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021950.1\|WP_004151308.1\|2013477_2013636_+\|DUF1317-family-protein	unknown	unknown	gnl\|CDD\|284449
NZ_CP021950.1\|WP_004151300.1\|2010020_2010710_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP021950.1\|WP_001548453.1\|2009397_2009619_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|336083
NZ_CP021950.1\|WP_004151284.1\|2001877_2002408_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|379158
NZ_CP021950.1\|WP_004151291.1\|2004288_2004936_-\|DUF551-domain-containing-protein	unknown	unknown	gnl\|CDD\|367946
NZ_CP021950.1\|WP_004151304.1\|2011658_2011943_+\|host-nuclease-inhibitor-GamL	unknown	unknown	unknown
NZ_CP021950.1\|WP_004151310.1\|2013632_2014289_+\|DNA-methyltransferase	unknown	unknown	gnl\|CDD\|227069
NZ_CP021950.1\|WP_004151286.1\|2002534_2003170_-\|protein-ninG	unknown	unknown	gnl\|CDD\|368603
NZ_CP021950.1\|WP_004151285.1\|2002400_2002538_-\|YlcG-family-protein	unknown	unknown	unknown
NZ_CP021950.1\|WP_004151301.1\|2011060_2011276_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP021950.1\|WP_004151306.1\|2012800_2013481_+\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	1.68114e-32
NZ_CP021950.1\|WP_004151288.1\|2003332_2003788_-\|hypothetical-protein	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	1.50704e-78
NZ_CP021950.1\|WP_004151305.1\|2011958_2012804_+\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	3.75286e-34
NZ_CP021950.1\|WP_004151287.1\|2003162_2003333_-\|NinE-family-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	1.47696e-19
NZ_CP021950.1\|WP_004151296.1\|2006853_2008284_-\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	7.87266e-159
NZ_CP021950.1\|WP_004151295.1\|2006560_2006854_-\|protein-ren	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	0.000668668
NZ_CP021950.1\|WP_004151299.1\|2009659_2009893_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	9.32854e-22
NZ_CP021950.1\|WP_004151293.1\|2005108_2005951_-\|translation-repressor-RelE	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	0.000117969
NZ_CP021950.1\|WP_004151308.1\|2013477_2013636_+\|DUF1317-family-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	3.35548e-20
NZ_CP021950.1\|WP_004151300.1\|2010020_2010710_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	1.58097e-27
NZ_CP021950.1\|WP_001548453.1\|2009397_2009619_-\|hypothetical-protein	gnl\|CDD\|336083	pfam05269, Phage_CII, Bacteriophage CII protein. This family consists of several phage CII regulatory proteins. CII plays a key role in the lysis-lysogeny decision in bacteriophage lambda and related phages.	1.55058e-09
NZ_CP021950.1\|WP_004151284.1\|2001877_2002408_-\|HNH-endonuclease	gnl\|CDD\|379158	pfam13392, HNH_3, HNH endonuclease. This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.	8.84074e-15
NZ_CP021950.1\|WP_004151291.1\|2004288_2004936_-\|DUF551-domain-containing-protein	gnl\|CDD\|367946	pfam04448, DUF551, Protein of unknown function (DUF551). This family represents the carboxy terminus of a protein of unknown function, found in dsDNA viruses with no RNA stage, including bacteriophages lambda and P22, and also in some Escherichia coli prophages.	8.71432e-11
NZ_CP021950.1\|WP_004151310.1\|2013632_2014289_+\|DNA-methyltransferase	gnl\|CDD\|227069	COG4725, IME4, Transcriptional activator, adenine-specific DNA methyltransferase [Signal transduction mechanisms / Transcription].	6.42213e-22
NZ_CP021950.1\|WP_004151286.1\|2002534_2003170_-\|protein-ninG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	9.44908e-60

>NZ_CP021950.1|WP_004151296.1|2006853_2008284_-|AAA-family-ATPase
MTSDFMTPPHSIEAEQSVLGGLLLDDDNSERTQKVLSILKPESFYARPHQVIFAEMRQMYRDHKPVDLLTLFDALESKGLTETVGGFAYLAEMSKNTPSAANIVAYAMRVRETAMERYGIEKTTKAIELLYARNGMTAEQKFDAIQGLFTEITEHVKTGRRTGLRTFYDAVTDWSAEFDERLKPDGRSRGLSTGIRSLDELLGVKRIVRGSLFVIGARPKMGKTTLYTQMGINCATVENEPALMFSLEMPEGQMVEKITAQKGRISPNLFYPDMTKDDYGYRGDWNSDLQKATGVMGALIETNNLLIDDTPGISLAHVMAESRRIKRERGKVGMILVDYLTLMTADKAERNDLAYGLITKGLKILAKELDCVVVLLTQLNRDLEKRTNKRPLPSDSRDTGQIEQDCDYWLAIYREGAYDENANQSDTELLLRLNRHGETGVVYCEQRHGAIYDCDQEAASQRRREKEQKPTKRGGF
>NZ_CP021950.1|WP_004151295.1|2006560_2006854_-|protein-ren
MTGKDAILNYLKTHKTCSSPDVAAASGMTHTCINQAANILAKQGVLVAEARVWRTVYYRLATEEEIAGRKSTNQIFNECRQSPAMKRVLAVYGRTSA
>NZ_CP021950.1|WP_004151294.1|2006057_2006564_-|hypothetical-protein
MTITLQAVNKLIASMESAGELSIREQKFLKLAKEFRICSASLDAAIKTGNMLADQNAQLAAENVALKDINAWCKTDAFKNMYREFKTAEALGCSDADCMHDAMLVAIMHAPATPATDRIVAGIKADGVEEFAAKLRIPGDDQFFDALAKGIALAADDFAKQLREGADK
>NZ_CP021950.1|WP_004151293.1|2005108_2005951_-|translation-repressor-RelE
MTDITELAQSLKAAAEKASNGDWVKESGDGWEACCSANDQANGGFIIAHFVGPDAAENCEFVQAANPANVLALVEALEYYKSREERVTSLVRDNSKSWDELYRQVEAKGKRNVELVEALESEKRICATWRKTAESTSEKLEKAQAAERRWHRVASRVHEQACESDVKIDELEAIRAAAEKLVRCKGRYHSEQNYRALAALFGVNTPDLPPLEHENVHYADAAEMEIEALRQRIAELESRTVKLPPRVDSSNVPFAGNAWNCCLDEVEKRLTAAGIKMEAE
>NZ_CP021950.1|WP_004151291.1|2004288_2004936_-|DUF551-domain-containing-protein
MTNNQLAENSVIQLLNSVKLARDNAELADNRVDHSFYYALTIALEELQERRKAAMDSEPVLWAWHHLDMWHVTSHDGRARDLWLSGFKVIPLYRHAQPVLVIPDEMTAEQAYEIGYYYGDPVDVFARGANWMRQHIIDSTLAAAPQSPGSDPATVPGKWISVSERMPENDGAYLCWDNRYVTTYAFIFGAWQANQFIAKNITHWMPLPAGPQEVR
>NZ_CP021950.1|WP_004151288.1|2003332_2003788_-|hypothetical-protein
MNIPQCGIKLHNGNFSAIGKILQEQLSDGKCLRLQVKEWREKRSLSQNALSHMWYAEISEYLINSGRTDATPEWVKRNLKKTYLGCEEVTYTDFITGEKTTTWEPRHTSDLDTGEMHIFLTKVEAWCAQFGLALTIPHGCEYQQLQQKQEA
>NZ_CP021950.1|WP_004151287.1|2003162_2003333_-|NinE-family-protein
MSSLLAKVIERGIFRVPARRKRKVEDKPSDIPTLKDYTARLVDKKWLRLRARRPHA
>NZ_CP021950.1|WP_004151286.1|2002534_2003170_-|protein-ninG
MRKPARRKCAHCREWFHPAREGQVVCSFECASAIGKKQTAKAREAAKARAVKRQRESEKEGRQRRKARLAELRPNGYYKAQAQKAFNAYIRARDAALPCISCGETNPPDLHGGQWDCGHFKTVGAYPELRFEERNAHKQCKSCNAGAGKYTAKELTVAQQYEAGLVARYGQEYVDWLNGPHEMTNYRREDFIRIRDEYRAKLKALKQREAA
>NZ_CP021950.1|WP_004151285.1|2002400_2002538_-|YlcG-family-protein
MNHDIIERIRDRWKKLRLLRSRGTVLVDYLILRNFIASLSRGSYE
>NZ_CP021950.1|WP_004151284.1|2001877_2002408_-|HNH-endonuclease
MSKSEKSITQELLRTLLEYDPQTGIFRWKIKASSSAHPGDIAGCIDGQGYRVIRIYGKNRKAHRLAWLYVYGDEPEVIDHIDRNRSNNAIENLRAVTFSQNSANRAAKSKNKSGFTGVYWNELGKKWQASIVANGRTHYVGLFATAQEAAKARTEYARQLYANFYIPSFHDQEAAK
>NZ_CP021950.1|WP_001548453.1|2009397_2009619_-|hypothetical-protein
MESSTTRNKVEARRIESWLHSQIAELGTTNIAKVAGVNKSTVSRWRESLLPNMSLLLAILISNRPGEKGDFEA
>NZ_CP021950.1|WP_004151299.1|2009659_2009893_-|helix-turn-helix-domain-containing-protein
MKNPAVEKAISIAGSQKELAKRCGKAQSTICDWLNGKKRISPVHVPDLVAAVNGEIKAYEFRPDLPSIFPPPNNSAA
>NZ_CP021950.1|WP_004151300.1|2010020_2010710_+|helix-turn-helix-transcriptional-regulator
MDFSERLARAMSLAGYTQGRLAKEVGMAQSSVNKLLNGANGSRKTVEIASVLGVRPEWLSTGAGEMLADSIQITQMQTPVTPQNGIYRVDVLDVKASAGPGALITNDFIETIRAIEYTSEQARSLFGNRPAHHIKVITVTGDSMDTTISPGDEIFVDISSTHFDSDGVYVFVFGKTLHVKRLQMQRDRLAVISDNPIYEKWYVEPGDEDQFYVMARVLLRQSIEYKRFA
>NZ_CP021950.1|WP_004151301.1|2011060_2011276_+|hypothetical-protein
MSKENNGGPAYPTQGYEGLTVRDYFAAKAMQGWLAGYPAGINHPARSEEGFTVAELSYLMADAMLKAREEV
>NZ_CP021950.1|WP_004151303.1|2011375_2011570_+|hypothetical-protein
MANSIPNNGRAVMMRNRRTGAAWLVSFDYRDGSYWHEPQGNLRHIRRPYASRSIEPNLVPAGTH
>NZ_CP021950.1|WP_004151304.1|2011658_2011943_+|host-nuclease-inhibitor-GamL
MNAYRAYDVIEERKWAEQTLTEEKQKWIEDRAKEVFDSLPEDPYAALRQSVSSKSFPYEGLRSDKAGEVYNDLRTAIAYAQAEYDWDHRTGCPF
>NZ_CP021950.1|WP_004151305.1|2011958_2012804_+|phage-recombination-protein-Bet
MANELVITASSLAERGIDGATWSALKNSIYPGAKDESVMMALDYCRARNLDPLLKPVHLVPMSVKDSKSGKSEWRDVVMPGIGLYRIQADRSGDYAGAKEPEFGPDVTLTLTGIEVTVPQWCKYTVSKRMPSGEIVEFSAKEYWVENYATAGRDTTAPNAMWKKRPYGQLAKCAEAQALRKAWPEIGQQPTAEEMEGKTLEVDARDVTPRSTPEAPPLVASEETLQAITDLLTSLNKDWEQDFLPLCSNIFKRDIFQASQLTEEEAQKGFSFLQKKAQVAA
>NZ_CP021950.1|WP_004151306.1|2012800_2013481_+|YqaJ-viral-recombinase-family-protein
MTPEIILERTGIDVTRVEQGDESWHRLRLGVITASEVHNVISKPKSGKKWTDMKMSYFLTLLAEVCTGVAPEVNAKALAWGKQYEADARTLFEFTTDVKVTESPILFRDEGMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQFSMWVTGKDAWYFANYDPRMKREGIHHVVVERDDKYMSDFNEMVPEFISKMDESLAEIGFTFGEQWK
>NZ_CP021950.1|WP_004151308.1|2013477_2013636_+|DUF1317-family-protein
MKHYRDAITVGKVKCMYSVLHRGWLMPSGEVVRNPLKAQRLAEELDTKRGAR
>NZ_CP021950.1|WP_004151310.1|2013632_2014289_+|DNA-methyltransferase
MKRYSLIYADPAWSYGNTISNGAAVDHYPTMSLLDMKRLPVWELAADNAVLAMWYTGTHNQEAIELAEAWGFTVRTMKGFTWVKLNQLAELRITKALAEGDVTDFYDFLALLNAETRMNGGNHTRANTEDVLIATRGAGLERKHAGIKQVVYSPLGAHSEKPWEVRHRLELLYGDVPRIELFSRSAAPGWSHWGNQCATASVELIPGCAIDVVKTEAA

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Crispr_ID: NZ_CP021950_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021950_2

2492656-2492750

Orphan

Consensus_repeat	Method
ACTATGGTTTTTATGGTTTTTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021950_2

>merge|NZ_CP021950|2|2492656-2492750|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATGGTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATGACTGTGGTTTTTATGGTTTTTATT

>NZ_CP021950|2|2|2492656-2492750|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATG	GTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATG
ACTGTGGTTTTTATGGTTTTTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021950.1\|WP_002888323.1\|2501813_2502191_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP021950.1\|WP_002888321.1\|2502195_2503044_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP021950.1\|WP_002888345.1\|2491202_2492567_-\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP021950.1\|WP_002888347.1\|2490483_2491023_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP021950.1\|WP_002888329.1\|2498711_2499998_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP021950.1\|WP_002888337.1\|2494506_2495205_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP021950.1\|WP_002888368.1\|2480054_2481764_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP021950.1\|WP_002888340.1\|2492891_2494517_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP021950.1\|WP_002888320.1\|2503299_2503779_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP021950.1\|WP_002888324.1\|2500989_2501811_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP021950.1\|WP_002888348.1\|2489749_2490409_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP021950.1\|WP_002888327.1\|2500003_2500993_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP021950.1\|WP_002888357.1\|2481774_2483277_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP021950.1\|WP_002888353.1\|2483414_2484110_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP021950.1\|WP_002888370.1\|2478871_2479717_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP021950.1\|WP_002888349.1\|2484285_2486643_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP021950.1\|WP_004151368.1\|2486830_2489737_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP021950.1\|WP_002888373.1\|2477975_2478743_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP021950.1\|WP_004147026.1\|2496308_2498657_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP021950.1\|WP_002888332.1\|2495237_2496065_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512

Protein	Function_ID	Function_description	E-value
NZ_CP021950.1\|WP_002888323.1\|2501813_2502191_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
NZ_CP021950.1\|WP_002888321.1\|2502195_2503044_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP021950.1\|WP_002888345.1\|2491202_2492567_-\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
NZ_CP021950.1\|WP_002888347.1\|2490483_2491023_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
NZ_CP021950.1\|WP_002888329.1\|2498711_2499998_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP021950.1\|WP_002888337.1\|2494506_2495205_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	5.03078e-66
NZ_CP021950.1\|WP_002888368.1\|2480054_2481764_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP021950.1\|WP_002888340.1\|2492891_2494517_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	6.55037e-173
NZ_CP021950.1\|WP_002888320.1\|2503299_2503779_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
NZ_CP021950.1\|WP_002888324.1\|2500989_2501811_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
NZ_CP021950.1\|WP_002888348.1\|2489749_2490409_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
NZ_CP021950.1\|WP_002888327.1\|2500003_2500993_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP021950.1\|WP_002888357.1\|2481774_2483277_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP021950.1\|WP_002888353.1\|2483414_2484110_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP021950.1\|WP_002888370.1\|2478871_2479717_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP021950.1\|WP_002888349.1\|2484285_2486643_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP021950.1\|WP_004151368.1\|2486830_2489737_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP021950.1\|WP_002888373.1\|2477975_2478743_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP021950.1\|WP_004147026.1\|2496308_2498657_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP021950.1\|WP_002888332.1\|2495237_2496065_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164

>NZ_CP021950.1|WP_002888345.1|2491202_2492567_-|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP021950.1|WP_002888347.1|2490483_2491023_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>NZ_CP021950.1|WP_002888348.1|2489749_2490409_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP021950.1|WP_004151368.1|2486830_2489737_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESIDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAGIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP021950.1|WP_002888349.1|2484285_2486643_+|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLIEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSHVNAWWAQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP021950.1|WP_002888353.1|2483414_2484110_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP021950.1|WP_002888357.1|2481774_2483277_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATVEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP021950.1|WP_002888368.1|2480054_2481764_+|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSKAALTH
>NZ_CP021950.1|WP_002888370.1|2478871_2479717_-|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVREACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP021950.1|WP_002888373.1|2477975_2478743_-|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR
>NZ_CP021950.1|WP_002888340.1|2492891_2494517_+|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEAHDAS
>NZ_CP021950.1|WP_002888337.1|2494506_2495205_+|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSDREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP021950.1|WP_002888332.1|2495237_2496065_-|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP021950.1|WP_004147026.1|2496308_2498657_+|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP021950.1|WP_002888329.1|2498711_2499998_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP021950.1|WP_002888327.1|2500003_2500993_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP021950.1|WP_002888324.1|2500989_2501811_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP021950.1|WP_002888323.1|2501813_2502191_+|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP021950.1|WP_002888321.1|2502195_2503044_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP021950.1|WP_002888320.1|2503299_2503779_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP021950_1	1.1\|2008714\|36\|NZ_CP021950\|CRISPRCasFinder	2008714-2008749	36	MK448233	Klebsiella phage ST11-VIM1phi8.1, complete genome	8447-8482	1.0
NZ_CP021950_1	1.1\|2008714\|36\|NZ_CP021950\|CRISPRCasFinder	2008714-2008749	36	MK448235	Klebsiella phage ST512-KPC3phi13.1, complete genome	8447-8482	1.0
NZ_CP021950_1	1.1\|2008714\|36\|NZ_CP021950\|CRISPRCasFinder	2008714-2008749	36	MK448231	Klebsiella phage ST101-KPC2phi6.1, complete genome	11383-11418	1.0

1. spacer 1.1|2008714|36|NZ_CP021950|CRISPRCasFinder matches to MK448233 (Klebsiella phage ST11-VIM1phi8.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

2. spacer 1.1|2008714|36|NZ_CP021950|CRISPRCasFinder matches to MK448235 (Klebsiella phage ST512-KPC3phi13.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

3. spacer 1.1|2008714|36|NZ_CP021950|CRISPRCasFinder matches to MK448231 (Klebsiella phage ST101-KPC2phi6.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

727416 : 738303

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004151613.1\|727416_730524_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
WP_004151612.1\|730578_731844_+	MFS transporter	NA	NA	NA	NA
WP_001620097.1\|731874_732963_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_002904006.1\|733049_733310_-	hypothetical protein	A0A077SK33	Escherichia_phage	3.5e-40	97.7
WP_004176269.1\|733607_734468_+	class A broad-spectrum beta-lactamase SHV-11	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002210513.1\|734488_735250_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004151610.1\|735510_736413_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	7.7e-159	99.3
WP_004151609.1\|736424_737690_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	6.6e-233	99.5
WP_002210516.1\|737682_738303_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_2

966508 : 1004973

uncultured_Caudovirales_phage(34.04%)

terminase,integrase

attL 996086:996100|attR 1002095:1002109

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152576.1\|966508_967375_-	hypothetical protein	A0A2H4IYR0	uncultured_Caudovirales_phage	1.9e-34	64.5
WP_004152575.1\|967374_968148_-	DUF2612 domain-containing protein	A0A2H4J1A9	uncultured_Caudovirales_phage	2.8e-77	54.4
WP_004152574.1\|968144_969341_-	hypothetical protein	A0A0M4RD32	Salmonella_phage	3.9e-158	72.9
WP_004152573.1\|969340_969694_-	hypothetical protein	A0A2H4J629	uncultured_Caudovirales_phage	2.3e-50	80.3
WP_004152572.1\|969695_970349_-	hypothetical protein	A0A2H4J8H6	uncultured_Caudovirales_phage	1.0e-59	63.5
WP_004152571.1\|970402_970969_-	hypothetical protein	NA	NA	NA	NA
WP_004199301.1\|971011_971194_-	hypothetical protein	NA	NA	NA	NA
WP_032441788.1\|971243_971591_-	hypothetical protein	A0A2H4J1A5	uncultured_Caudovirales_phage	4.7e-24	46.6
WP_004152569.1\|971583_972606_-	hypothetical protein	A0A2H4J1B2	uncultured_Caudovirales_phage	9.2e-100	54.2
WP_004152568.1\|972608_972911_-	hypothetical protein	A0A2H4J495	uncultured_Caudovirales_phage	2.0e-26	55.2
WP_004152567.1\|972911_973511_-	hypothetical protein	A0A2H4J1B3	uncultured_Caudovirales_phage	9.9e-54	57.6
WP_004152566.1\|973510_975514_-	lytic transglycosylase domain-containing protein	A0A2H4J9N7	uncultured_Caudovirales_phage	1.2e-247	63.6
WP_004152565.1\|975503_975656_-	hypothetical protein	A0A2H4J1A2	uncultured_Caudovirales_phage	7.6e-19	88.0
WP_004152564.1\|975691_976117_-	hypothetical protein	A0A2H4J2V6	uncultured_Caudovirales_phage	2.6e-40	63.4
WP_004199809.1\|976120_976561_-	DUF3277 family protein	A0A0M5M1K6	Salmonella_phage	3.3e-62	80.1
WP_004152177.1\|976571_977717_-	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	6.3e-166	76.9
WP_004152176.1\|977720_978161_-	hypothetical protein	A0A2H4J1A0	uncultured_Caudovirales_phage	1.6e-40	51.7
WP_001116156.1\|978255_978642_-	hypothetical protein	A0A2H4J1A4	uncultured_Caudovirales_phage	1.1e-48	78.2
WP_000834982.1\|978641_979148_-	hypothetical protein	NA	NA	NA	NA
WP_000113538.1\|979144_979564_-	DUF4054 domain-containing protein	A0A0M5M3S2	Salmonella_phage	3.3e-40	60.7
WP_000725700.1\|979532_979814_-	hypothetical protein	NA	NA	NA	NA
WP_001132269.1\|979853_980795_-	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	1.7e-137	77.1
WP_000528476.1\|980806_981301_-	hypothetical protein	A0A2H4JHM9	uncultured_Caudovirales_phage	4.2e-50	62.7
WP_004199270.1\|981304_982507_-	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	2.6e-106	54.1
WP_004152174.1\|982558_983107_-	hypothetical protein	A0A0M4REK0	Salmonella_phage	3.0e-49	56.3
WP_004152173.1\|983162_984614_-	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	3.8e-192	68.8
WP_004152172.1\|984851_986252_-\|terminase	PBSX family phage terminase large subunit	A0A077KAW0	Edwardsiella_phage	9.4e-188	69.0
WP_004152171.1\|986202_986955_-	hypothetical protein	A0A077KBY7	Edwardsiella_phage	4.0e-12	66.0
WP_004152170.1\|987056_987377_-	hypothetical protein	NA	NA	NA	NA
WP_004153952.1\|987611_988001_-	lipase chaperone	A0A192Y6H8	Salmonella_phage	9.4e-21	49.2
WP_004152169.1\|987997_988528_-	lysozyme	K7PLY1	Enterobacteria_phage	2.7e-79	77.1
WP_004146526.1\|988530_988779_-	hypothetical protein	NA	NA	NA	NA
WP_004152167.1\|989184_989967_-	antitermination protein	F1C595	Cronobacter_phage	7.2e-113	76.8
WP_004198239.1\|989963_990440_-	hypothetical protein	A0A286N2Q1	Klebsiella_phage	1.8e-90	100.0
WP_004198233.1\|990436_991399_-	zinc-binding domain of primase-helicase family protein	A0A286N2Q0	Klebsiella_phage	4.8e-183	99.4
WP_004198228.1\|991400_993059_-	DEAD/DEAH box helicase	A0A286N2P9	Klebsiella_phage	0.0e+00	96.0
WP_004152162.1\|993635_993857_-	helix-turn-helix transcriptional regulator	A0A286S2C1	Klebsiella_phage	3.0e-32	100.0
WP_004152161.1\|993954_994623_+	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	2.4e-125	99.5
WP_004152160.1\|994793_995108_+	hypothetical protein	A0A286S1T9	Klebsiella_phage	1.0e-49	100.0
WP_004152159.1\|995100_995289_+	hypothetical protein	A0A286S1P8	Klebsiella_phage	4.6e-26	100.0
WP_004152158.1\|995458_995824_+	hypothetical protein	A0A286S1Q6	Klebsiella_phage	6.9e-58	99.2
WP_004152157.1\|995816_996071_+	hypothetical protein	A0A286SGR4	Klebsiella_phage	3.1e-41	97.6
WP_004177208.1\|996042_996261_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	6.6e-32	98.6
996086:996100	attL	NA	NA	NA	NA
WP_004152156.1\|996257_996683_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	3.5e-53	77.9
WP_004152155.1\|996679_996874_+	hypothetical protein	NA	NA	NA	NA
WP_004152154.1\|996870_997698_+	hypothetical protein	Q8W654	Enterobacteria_phage	5.5e-111	84.0
WP_004152153.1\|997802_998321_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.7e-94	98.8
WP_004154298.1\|998326_999037_+	DNA-binding protein	A0A286S260	Klebsiella_phage	2.1e-111	88.3
WP_004152151.1\|999026_999251_+	hypothetical protein	A0A286S2B3	Klebsiella_phage	3.1e-29	89.2
WP_004152150.1\|999247_999460_+	hypothetical protein	A0A286S2B6	Klebsiella_phage	3.4e-33	98.6
WP_004152149.1\|999456_999936_+	hypothetical protein	NA	NA	NA	NA
WP_004152148.1\|1000114_1000357_+	hypothetical protein	A0A0M4RTZ2	Salmonella_phage	2.2e-20	73.8
WP_004152147.1\|1000337_1001519_-\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	5.6e-202	84.2
WP_016197745.1\|1001715_1002264_+	DJ-1/PfpI family protein	NA	NA	NA	NA
1002095:1002109	attR	NA	NA	NA	NA
WP_004152145.1\|1002462_1003995_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	1.1e-21	30.0
WP_004152144.1\|1004211_1004973_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-20	32.5

DBSCAN-SWA_3

1037906 : 1052314

Salmonella_phage(23.08%)

integrase,transposase

attL 1037688:1037703|attR 1049620:1049635

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1037688:1037703	attL	NA	NA	NA	NA
WP_002901815.1\|1037906_1038578_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	4.5e-79	59.6
WP_071531199.1\|1038764_1039592_+	FRG domain-containing protein	A0A1S6KZX9	Salmonella_phage	8.4e-19	30.2
WP_002901813.1\|1039667_1040933_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	9.6e-208	82.7
WP_002901812.1\|1040934_1041354_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.4e-35	57.5
WP_004152765.1\|1041433_1042918_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004152776.1\|1043815_1044238_-	hypothetical protein	K7P834	Enterobacteria_phage	3.6e-26	45.3
WP_001067855.1\|1044830_1045535_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_088224434.1\|1045995_1046283_+	hypothetical protein	NA	NA	NA	NA
WP_004201102.1\|1046284_1046965_+	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	8.2e-121	91.2
WP_004151898.1\|1046961_1047390_+	hypothetical protein	M9NYX4	Enterobacteria_phage	7.5e-64	80.3
WP_004151899.1\|1047386_1048049_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-105	84.6
WP_004153574.1\|1048256_1049444_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	1.1e-120	52.4
WP_004151901.1\|1049620_1050511_+	peptide ABC transporter permease SapC	NA	NA	NA	NA
1049620:1049635	attR	NA	NA	NA	NA
WP_004140266.1\|1050510_1051503_+	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	3.0e-07	27.2
WP_004140269.1\|1051504_1052314_+	peptide ABC transporter ATP-binding protein SapF	A0A2H4PQG7	Staphylococcus_phage	2.1e-14	28.9

DBSCAN-SWA_4

1172495 : 1180344

Pseudomonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002901225.1\|1172495_1173245_-	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	4.3e-14	29.1
WP_004140447.1\|1173411_1174317_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004152360.1\|1174323_1175589_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	7.6e-197	79.6
WP_002901192.1\|1175591_1176011_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	5.5e-35	57.5
WP_004152765.1\|1176089_1177574_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004152765.1\|1177999_1179484_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_002901096.1\|1180101_1180344_+	DinI family protein	Q6UAW0	Klebsiella_phage	4.1e-27	72.2

DBSCAN-SWA_5

1430679 : 1528002

Salmonella_phage(54.1%)

head,integrase,protease,capsid,tail,lysis,portal,plate,terminase,transposase,tRNA

attL 1486205:1486223|attR 1528077:1528095

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002898139.1\|1430679_1431972_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	7.3e-94	44.7
WP_002898137.1\|1432062_1433406_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	7.3e-81	40.8
WP_002898132.1\|1433414_1434026_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_004150846.1\|1434148_1438402_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	5.2e-88	49.2
WP_000228469.1\|1438537_1439032_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_004141839.1\|1439537_1440533_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	3.3e-62	44.0
WP_002898017.1\|1440647_1442414_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	2.3e-21	25.9
WP_004150847.1\|1442414_1444136_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
WP_002898014.1\|1444180_1444882_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|1445235_1445454_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002896522.1\|1445574_1447854_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_002896520.1\|1447884_1448202_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|1448527_1448749_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_004150848.1\|1448825_1450766_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_002896440.1\|1450762_1451878_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_002896437.1\|1452024_1453683_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_002896434.1\|1454102_1454798_+	aquaporin Z	NA	NA	NA	NA
WP_004147773.1\|1454913_1455813_+	lysine exporter LysO family protein	NA	NA	NA	NA
WP_002896412.1\|1455956_1457609_+	hydroxylamine reductase	NA	NA	NA	NA
WP_002896410.1\|1457619_1458588_+	NADH oxidoreductase	NA	NA	NA	NA
WP_002896408.1\|1458799_1459234_-	DoxX family protein	NA	NA	NA	NA
WP_002896406.1\|1459385_1461104_+	ubiquinone-dependent pyruvate dehydrogenase	NA	NA	NA	NA
WP_002896404.1\|1461142_1462144_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_002896401.1\|1462154_1463597_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002896399.1\|1463684_1464698_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_002896397.1\|1464694_1465525_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	4.1e-05	31.6
WP_004150851.1\|1465556_1466696_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_002896394.1\|1467573_1468089_+	lipoprotein	NA	NA	NA	NA
WP_002896392.1\|1468315_1469044_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	1.2e-29	37.1
WP_002896390.1\|1469064_1469796_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896386.1\|1469802_1470519_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_004150852.1\|1470518_1471187_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_002896384.1\|1471370_1472102_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896382.1\|1472144_1473617_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	7.9e-28	31.8
WP_002896380.1\|1473613_1474330_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.1e-34	36.9
WP_002896378.1\|1474408_1475536_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A2K5B251	Erysipelothrix_phage	1.3e-19	25.6
WP_002896376.1\|1475577_1476066_-	DUF2593 family protein	NA	NA	NA	NA
WP_002896372.1\|1476123_1476969_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_002896371.1\|1476965_1477919_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_002896370.1\|1477929_1479063_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	2.2e-30	34.9
WP_002896368.1\|1479226_1480339_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_002896365.1\|1480687_1481167_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_002896363.1\|1481255_1482158_-	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	2.0e-34	35.3
WP_002896354.1\|1482979_1483267_-	YbjC family protein	NA	NA	NA	NA
WP_002896352.1\|1483469_1483733_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	1.6e-27	73.1
WP_002896351.1\|1483739_1484123_-	membrane protein	NA	NA	NA	NA
WP_004179131.1\|1484389_1486075_+	transporter	NA	NA	NA	NA
1486205:1486223	attL	NA	NA	NA	NA
WP_000972391.1\|1486294_1486513_-	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	7.5e-20	69.0
WP_002896225.1\|1486604_1487705_-	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	4.9e-176	87.4
WP_002896224.1\|1487701_1488187_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	7.2e-63	75.6
WP_004201219.1\|1489714_1491253_-\|transposase	IS66-like element ISKpn24 family transposase	A0A0P0ZEB3	Stx2-converting_phage	5.1e-280	94.3
WP_000612626.1\|1491301_1491649_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_003031976.1\|1491645_1492050_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.3e-69	98.5
WP_002896220.1\|1493265_1493385_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.2e-13	87.2
WP_002896204.1\|1493399_1493699_-\|tail	phage tail assembly protein	E5G6P9	Salmonella_phage	3.7e-33	79.0
WP_002896201.1\|1493751_1494267_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	1.3e-81	85.4
WP_002896193.1\|1494276_1495449_-\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.9e-210	93.3
WP_002896191.1\|1495587_1496664_-\|tail	phage tail protein	Q37842	Escherichia_phage	1.2e-25	44.8
WP_002896188.1\|1496693_1496897_-	hypothetical protein	NA	NA	NA	NA
WP_002896186.1\|1496893_1497625_-	hypothetical protein	NA	NA	NA	NA
WP_004152882.1\|1497628_1500580_-	hypothetical protein	A0A2H4N7A3	Pectobacterium_phage	1.2e-06	50.9
WP_004150856.1\|1500581_1501181_-\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.3e-58	60.5
WP_002896182.1\|1501173_1502082_-\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	7.6e-106	66.9
WP_002896179.1\|1502068_1502431_-\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	5.8e-49	84.7
WP_002896177.1\|1502427_1503000_-\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	4.7e-77	72.3
WP_004150857.1\|1503094_1503787_+	hypothetical protein	NA	NA	NA	NA
WP_002896175.1\|1503783_1504230_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.2e-50	71.2
WP_002896172.1\|1504222_1504654_-\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	9.9e-64	82.5
WP_002896168.1\|1504749_1505178_-\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	9.6e-51	77.9
WP_002896163.1\|1505174_1505558_-	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	2.1e-17	42.0
WP_002896161.1\|1505562_1506072_-	lysozyme	E5G6N1	Salmonella_phage	2.1e-81	83.4
WP_002896158.1\|1506052_1506268_-	hypothetical protein	E5G6N0	Salmonella_phage	3.6e-30	90.1
WP_002896155.1\|1506271_1506475_-\|tail	tail protein X	A0A1S6KZY4	Salmonella_phage	1.3e-29	88.1
WP_002896151.1\|1506474_1506939_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	8.4e-77	89.0
WP_000059191.1\|1507034_1507685_-\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
WP_002895972.1\|1507688_1508747_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	1.1e-180	93.1
WP_002895967.1\|1508763_1509597_-\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	6.3e-123	88.8
WP_004150858.1\|1509739_1511506_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.0
WP_002895959.1\|1511505_1512531_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	7.6e-171	86.7
WP_004199124.1\|1512592_1514335_-	AIPR family protein	NA	NA	NA	NA
WP_000700647.1\|1514610_1515288_-	hypothetical protein	NA	NA	NA	NA
WP_001217575.1\|1515402_1515636_-	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_001154434.1\|1515646_1515835_-	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_004152765.1\|1515935_1517420_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004150862.1\|1517898_1520313_-	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.5
WP_004150863.1\|1520309_1521167_-	DNA adenine methylase	E5G6L8	Salmonella_phage	2.0e-156	95.4
WP_000752622.1\|1521163_1521391_-	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	6.0e-36	98.7
WP_004150864.1\|1521390_1521624_-	DUF2732 family protein	E5G6L6	Salmonella_phage	4.1e-32	96.1
WP_000963473.1\|1521691_1522033_-	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	4.6e-56	99.1
WP_000956179.1\|1521996_1522197_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	1.6e-32	97.0
WP_000460893.1\|1522204_1522714_-	phage regulatory CII family protein	E5G6L3	Salmonella_phage	5.8e-87	98.8
WP_000188448.1\|1522746_1522968_-	hypothetical protein	NA	NA	NA	NA
WP_004152885.1\|1523113_1523992_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.7e-30	39.9
WP_004150866.1\|1524003_1524948_+	hypothetical protein	NA	NA	NA	NA
WP_004152765.1\|1525046_1526531_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004151720.1\|1526949_1528002_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.0e-106	57.0
1528077:1528095	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1974529 : 2019804

Escherichia_phage(26.42%)

head,integrase,lysis,tRNA

attL 1967742:1967788|attR 2016876:2016922

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1967742:1967788	attL	NA	NA	NA	NA
WP_004151249.1\|1974529_1977007_-	MoaD/ThiS family protein	F1C5A7	Cronobacter_phage	2.7e-198	45.6
WP_004151250.1\|1976993_1977389_-	hypothetical protein	F1C5F2	Cronobacter_phage	8.0e-36	54.0
WP_004199076.1\|1977385_1977856_-	hypothetical protein	R9TPR6	Aeromonas_phage	2.5e-28	41.0
WP_004165520.1\|1977855_1978275_-	hypothetical protein	A0A2P1MXB5	Escherichia_phage	1.8e-30	48.5
WP_004151253.1\|1978374_1981821_-	tape measure protein	Q5G8W8	Enterobacteria_phage	1.4e-163	48.6
WP_004151254.1\|1981913_1982417_-	hypothetical protein	NA	NA	NA	NA
WP_004151255.1\|1982544_1983330_-	phage repressor protein	A0A2L1IV39	Escherichia_phage	1.9e-84	59.7
WP_004151256.1\|1983395_1984109_-	hypothetical protein	H6WRU8	Salmonella_phage	3.9e-49	50.2
WP_004151257.1\|1984098_1984269_-	Arc family DNA-binding protein	I6R9A8	Salmonella_phage	6.1e-17	87.0
WP_004151258.1\|1984368_1984728_+	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.8e-16	47.5
WP_004151259.1\|1984744_1985215_-	hypothetical protein	NA	NA	NA	NA
WP_004151260.1\|1985508_1985763_-	hypothetical protein	K7PM89	Enterobacteria_phage	6.7e-20	73.0
WP_004151261.1\|1985765_1986521_-	DNA-binding protein	K7PGT4	Enterobacteria_phage	2.4e-60	51.0
WP_004151262.1\|1986696_1987374_-	hypothetical protein	F1C5E8	Cronobacter_phage	4.8e-73	57.9
WP_004151263.1\|1987426_1988179_-	Ig domain-containing protein	G0ZNE6	Cronobacter_phage	5.8e-43	42.1
WP_088356260.1\|1988247_1988640_-	hypothetical protein	G0ZNE4	Cronobacter_phage	2.6e-34	51.9
WP_004151265.1\|1988636_1989062_-	hypothetical protein	R9TPP7	Aeromonas_phage	5.1e-28	47.9
WP_004151266.1\|1989064_1989427_-	hypothetical protein	A0A173GCE0	Salmonella_phage	1.8e-18	45.0
WP_004151267.1\|1989426_1989600_-	hypothetical protein	I6R0P9	Salmonella_phage	1.4e-13	56.1
WP_004151268.1\|1989599_1989980_-	hypothetical protein	F1C5E2	Cronobacter_phage	5.3e-29	55.3
WP_004151269.1\|1989982_1990222_-	hypothetical protein	NA	NA	NA	NA
WP_004151270.1\|1990232_1991327_-	hypothetical protein	F1C5E1	Cronobacter_phage	1.7e-123	62.8
WP_004151271.1\|1991338_1991767_-	hypothetical protein	F1C5E0	Cronobacter_phage	1.6e-42	60.8
WP_004151272.1\|1991770_1993156_-	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	2.3e-154	60.0
WP_004151273.1\|1993228_1993705_-	hypothetical protein	NA	NA	NA	NA
WP_004151274.1\|1993746_1994751_-\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	9.0e-116	69.7
WP_004151275.1\|1994725_1996147_-	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	9.6e-148	57.1
WP_004151276.1\|1996159_1997632_-	hypothetical protein	A0A1W6JNY3	Morganella_phage	1.3e-248	82.5
WP_004151277.1\|1997631_1998234_-	hypothetical protein	G8C7P2	Escherichia_phage	5.4e-76	80.9
WP_004151279.1\|1998604_1998934_+	hypothetical protein	NA	NA	NA	NA
WP_004151280.1\|1999039_1999504_-\|lysis	lysis protein	Q76H63	Enterobacteria_phage	2.4e-55	73.2
WP_004151281.1\|1999500_2000031_-	lysozyme	G9L6J6	Escherichia_phage	6.0e-79	78.5
WP_004151282.1\|2000033_2000282_-	hypothetical protein	NA	NA	NA	NA
WP_004151283.1\|2001191_2001881_-	antitermination protein	I6PDF8	Cronobacter_phage	1.4e-56	54.5
WP_004151284.1\|2001877_2002408_-	HNH endonuclease	A0A193GYW9	Enterobacter_phage	5.2e-30	43.1
WP_004151285.1\|2002400_2002538_-	YlcG family protein	NA	NA	NA	NA
WP_004151286.1\|2002534_2003170_-	protein ninG	M9NYX8	Enterobacteria_phage	2.7e-81	77.9
WP_004151287.1\|2003162_2003333_-	NinE family protein	G8C7V4	Escherichia_phage	1.3e-14	73.2
WP_004151288.1\|2003332_2003788_-	hypothetical protein	K7P7B8	Enterobacteria_phage	8.0e-56	69.5
WP_004151291.1\|2004288_2004936_-	DUF551 domain-containing protein	A5LH60	Enterobacteria_phage	4.5e-12	32.6
WP_004151293.1\|2005108_2005951_-	translation repressor RelE	A0A2H4FRZ0	Salmonella_phage	1.8e-29	60.8
WP_004151294.1\|2006057_2006564_-	hypothetical protein	A0A0A6Z565	Enterobacter_phage	3.0e-27	59.6
WP_004151295.1\|2006560_2006854_-	protein ren	O48423	Enterobacteria_phage	3.3e-26	65.6
WP_004151296.1\|2006853_2008284_-	AAA family ATPase	Q9MCT4	Escherichia_phage	2.6e-185	66.7
WP_004151297.1\|2008273_2009173_-	hypothetical protein	F1C5C3	Cronobacter_phage	5.4e-88	54.9
WP_001548453.1\|2009397_2009619_-	hypothetical protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_004151299.1\|2009659_2009893_-	helix-turn-helix domain-containing protein	G8C7U2	Escherichia_phage	4.3e-13	50.7
WP_004151300.1\|2010020_2010710_+	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	4.3e-61	52.2
WP_004151301.1\|2011060_2011276_+	hypothetical protein	B5WZV1	Pseudomonas_phage	1.6e-09	48.6
WP_004151303.1\|2011375_2011570_+	hypothetical protein	NA	NA	NA	NA
WP_004151304.1\|2011658_2011943_+	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	8.0e-30	62.8
WP_004151305.1\|2011958_2012804_+	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	6.9e-69	59.2
WP_004151306.1\|2012800_2013481_+	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	7.9e-124	93.4
WP_004151308.1\|2013477_2013636_+	DUF1317 family protein	A0A0N7CHV0	Escherichia_phage	3.0e-10	60.8
WP_004151310.1\|2013632_2014289_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-113	87.5
WP_004151312.1\|2014285_2015053_+	hypothetical protein	D5LH17	Escherichia_phage	1.7e-66	53.4
WP_004151314.1\|2015049_2015268_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.2e-09	47.2
WP_004151316.1\|2015269_2015485_+	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	4.0e-13	52.9
WP_004151317.1\|2015486_2015822_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_004151318.1\|2015698_2016862_+\|integrase	site-specific integrase	G8C7S0	Escherichia_phage	3.3e-202	87.3
WP_004143017.1\|2017292_2018159_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-30	34.8
2016876:2016922	attR	NA	NA	NA	NA
WP_004143016.1\|2018160_2018373_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_004143010.1\|2018418_2019804_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.5e-46	35.4

DBSCAN-SWA_7

2229359 : 2241013

Enterobacteria_phage(70.0%)

integrase

attL 2229809:2229823|attR 2252866:2252880

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004144574.1\|2229359_2230463_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-62	40.5
2229809:2229823	attL	NA	NA	NA	NA
WP_002889940.1\|2230473_2231727_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	8.9e-89	44.9
WP_002889938.1\|2232079_2233270_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	6.4e-145	62.7
WP_004152029.1\|2233257_2234208_+	cobyrinic acid a,c-diamide synthase	A0A1X9IGI7	Lactococcus_phage	1.2e-13	27.1
WP_004152979.1\|2234207_2234633_+	hypothetical protein	NA	NA	NA	NA
WP_002889930.1\|2235201_2235768_-	phage polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.5e-59	64.3
WP_002889919.1\|2235785_2236031_-	hypothetical protein	Q7M294	Enterobacteria_phage	1.9e-19	58.0
WP_002889917.1\|2236027_2236765_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	9.0e-73	60.7
WP_002889915.1\|2237306_2237573_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	2.6e-30	71.6
WP_024940872.1\|2237569_2238127_+	ash family protein	Q7M2A7	Enterobacteria_phage	1.8e-33	70.4
WP_002889911.1\|2238123_2238351_+	hypothetical protein	NA	NA	NA	NA
WP_002889897.1\|2238347_2238668_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_088356261.1\|2238679_2241013_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	82.0
2252866:2252880	attR	NA	NA	NA	NA

DBSCAN-SWA_8

3783990 : 3817248

uncultured_Caudovirales_phage(73.33%)

head,integrase,protease,capsid,tail,portal,terminase,tRNA

attL 3801598:3801615|attR 3817593:3817610

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002919147.1\|3783990_3784938_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	2.2e-07	37.2
WP_002919144.1\|3784952_3785462_-	peptide deformylase	E3SLL2	Synechococcus_phage	2.6e-18	40.3
WP_002919139.1\|3785590_3786715_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_002919137.1\|3786686_3787160_+	DUF494 domain-containing protein	NA	NA	NA	NA
WP_004145330.1\|3787185_3787728_+	hypothetical protein	NA	NA	NA	NA
WP_002919132.1\|3787732_3788305_+	L-threonylcarbamoyladenylate synthase type 1 TsaC	NA	NA	NA	NA
WP_002919126.1\|3788308_3789127_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_002919125.1\|3789123_3789381_+	DUF1488 domain-containing protein	NA	NA	NA	NA
WP_002919123.1\|3789356_3789911_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_002919103.1\|3795706_3795928_-	membrane protein	NA	NA	NA	NA
WP_002919102.1\|3796221_3799332_-	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_002919101.1\|3799344_3800484_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004150972.1\|3800862_3801513_+	acrEF/envCD operon transcriptional regulator	NA	NA	NA	NA
3801598:3801615	attL	NA	NA	NA	NA
WP_004150971.1\|3801788_3803015_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.8e-150	62.2
WP_004150970.1\|3803107_3804049_+	hypothetical protein	NA	NA	NA	NA
WP_001547839.1\|3804230_3804515_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_004150969.1\|3804525_3805305_+	hypothetical protein	Q8HA02	Enterobacteria_phage	6.2e-40	51.5
WP_106918304.1\|3805756_3806026_+	host cell division inhibitor Icd-like protein	A0A2H4JGW3	uncultured_Caudovirales_phage	2.4e-44	94.4
WP_001549752.1\|3806018_3806207_+	hypothetical protein	NA	NA	NA	NA
WP_004150967.1\|3806199_3806514_+	hypothetical protein	NA	NA	NA	NA
WP_004150966.1\|3806510_3806879_+	hypothetical protein	A0A2H4JCX7	uncultured_Caudovirales_phage	3.7e-51	81.1
WP_001549749.1\|3806875_3807241_+	hypothetical protein	NA	NA	NA	NA
WP_004150965.1\|3807240_3809376_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	3.4e-205	62.4
WP_004150964.1\|3809718_3810054_+	hypothetical protein	NA	NA	NA	NA
WP_004150963.1\|3810102_3810615_-	hypothetical protein	NA	NA	NA	NA
WP_001549743.1\|3810878_3812045_+\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	9.8e-207	95.9
WP_001547826.1\|3812096_3812657_+\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.2e-98	95.7
WP_004150962.1\|3812658_3813900_+\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	1.0e-230	96.5
WP_004150961.1\|3813896_3814232_+\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	3.7e-26	57.8
WP_001547824.1\|3814228_3814528_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	3.4e-39	80.8
WP_004150959.1\|3814527_3814971_+	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	2.8e-77	91.8
WP_000113647.1\|3815246_3815603_+\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	5.5e-60	99.2
WP_004150955.1\|3815586_3817248_+\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	0.0e+00	98.0
3817593:3817610	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP021951

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

24158 : 88397

Escherichia_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000082736.1\|24158_25139_+\|transposase	IS5-like element ISEc68 family transposase	Q38213	Escherichia_phage	1.4e-153	80.9
WP_032441898.1\|26321_27845_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-88	38.9
WP_032441899.1\|27834_29073_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_001459731.1\|29069_29753_+	YecA family protein	NA	NA	NA	NA
WP_013214044.1\|29805_33090_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	4.3e-66	27.6
WP_009310009.1\|33086_33842_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_000443938.1\|34701_36153_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_013214046.1\|36145_38188_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_032441900.1\|38374_44110_+	DUF4011 domain-containing protein	NA	NA	NA	NA
WP_003031976.1\|44563_44968_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.3e-69	98.5
WP_000612626.1\|44964_45312_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_032441901.1\|46631_48182_-	PAS domain-containing protein	A0A1B0V854	Salmonella_phage	6.3e-84	99.4
WP_001389365.1\|48210_48975_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001137892.1\|49467_50052_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000004159.1\|50051_51290_-	MFS transporter	NA	NA	NA	NA
WP_000219391.1\|51286_52192_-	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_001067855.1\|52313_53018_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_087758686.1\|53008_53164_+	replication initiator protein	NA	NA	NA	NA
WP_000470728.1\|53195_53873_-	tetracycline resistance transcriptional repressor TetR(A)	NA	NA	NA	NA
WP_000804064.1\|53951_55151_+	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_000058717.1\|55182_56067_-	EamA family transporter	NA	NA	NA	NA
WP_001351729.1\|56204_56597_-	cysteine hydrolase	NA	NA	NA	NA
WP_004200823.1\|58410_58719_+	hypothetical protein	K7PKY8	Enterobacterial_phage	1.1e-08	31.7
WP_025403925.1\|58823_59375_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	1.9e-19	35.2
WP_004199332.1\|59694_59973_+	replication regulatory protein RepA	NA	NA	NA	NA
WP_099913970.1\|60189_60267_+	RepA leader peptide Tap	NA	NA	NA	NA
WP_004200825.1\|60259_61117_+	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_004200826.1\|62484_62769_+	hypothetical protein	A0A1S6L2Z2	Erwinia_phage	1.5e-07	43.2
WP_004200827.1\|62778_63207_+	hypothetical protein	NA	NA	NA	NA
WP_004200832.1\|64533_66729_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_004152291.1\|66725_68042_-	ATP-binding protein	NA	NA	NA	NA
WP_000421673.1\|68045_70355_-	ATPase	NA	NA	NA	NA
WP_004200835.1\|70883_71852_+	phage exclusion protein	NA	NA	NA	NA
WP_004200837.1\|72089_73085_-\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	3.5e-19	29.2
WP_004200838.1\|73592_74141_+	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_017896188.1\|74750_75635_-	hypothetical protein	NA	NA	NA	NA
WP_077255340.1\|76546_76972_+	hypothetical protein	NA	NA	NA	NA
WP_004200841.1\|76988_77852_+	hypothetical protein	NA	NA	NA	NA
WP_004200842.1\|78501_80265_-	DUF262 domain-containing protein	C4MZ12	Escherichia_phage	2.9e-08	41.3
WP_001567369.1\|80882_81515_+	hypothetical protein	NA	NA	NA	NA
WP_001567368.1\|81543_82947_-\|transposase	ISNCY-like element ISKpn21 family transposase	NA	NA	NA	NA
WP_003026803.1\|83147_83630_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003026799.1\|83617_83884_-	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_001567367.1\|84128_84563_-	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_001567366.1\|84609_85158_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_017896554.1\|85651_85960_+	hypothetical protein	NA	NA	NA	NA
WP_004201219.1\|86858_88397_-\|transposase	IS66-like element ISKpn24 family transposase	A0A0P0ZEB3	Stx2-converting_phage	5.1e-280	94.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP021952

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP021953

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP021950

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP021951

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection