CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP022150	Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_2, complete sequence	0 crisprs	NA	0	0
NZ_CP022148	Enterobacter roggenkampii strain 704SK10 chromosome, complete genome	1 crisprs	DEDDh,DinG,cas3,csa3,WYL,PD-DExK	4	6
NZ_CP022149	Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_1, complete sequence	1 crisprs	NA	1	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022148_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022148_1

2017910-2018539

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTACGGCAGTG	PILER-CR
TTTCTAAGCTGCCTGTACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTACGGCAGTGAAC	CRT
GTTATTTTCTAAGCTGCCTGTACGGCAGTGAAC	PILER-CR

10 spacers

The CRISPR arrays of NZ_CP022148_1

>merge|NZ_CP022148|1|2017910-2018539|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
TTTCTAAGCTGCCTGTACGACAGTGAACTAGTCGGCCTTCTTTTGGCGGCAAGCCACAGATTTCTAAGCTGCCTGTACGGCAGTGAACGCTCGTCACCAGGGTTAACTGATTTGTCGGAATTTTCTAAGCTGCCTGTACGGCAGTGAACTTACCGTTTCAAAGTGGAATACTGCAGGACGTTTTCTAAGCTGCCTGTACGGCAGTGGACAGGAGGAACTTATGGCAATTTTAGTGGAAGCTTTTCTAAGCTGCCTGTACGGCATTGAACGGCAATGGTCCGGACGGTCGCCCTGAATTCCATTTCTAAGCTGCCTGTACGGCAGTGAACTTAGGTGGCGGGGTGATGGAGGATGTGTCGGTTTTCTAAGCTGCCTGTACGGCAGTGAACGTGGATGGTCCTCGCGCCCTCTGGTGTTGTTTTTTTCTAAGCTGCCTGTACGGCAGTGAACGGGTAATACCCATCAAAGGGGCGAGCACGTATTTTCTAAGCTGCCTGTACGGCAGTGAACAAGGCATTCAAAAGCCTGTAAGGGGACGTTATTTTCTAAGCTGCCTGTACGGCAGTGAACGCAAGGGATGGCAAAAGTGATGGCGTCGTTCGTTTCTAAGCTGCCTGTACGGCAGTGAAC

>NZ_CP022148|1|1|2017910-2018235|PILER-CR
TTTCTAAGCTGCCTGTACGACAGTG	AACTAGTCGGCCTTCTTTTGGCGGCAAGCCACAGA
TTTCTAAGCTGCCTGTACGGCAGTG	AACGCTCGTCACCAGGGTTAACTGATTTGTCGGAAT
TTTCTAAGCTGCCTGTACGGCAGTG	AACTTACCGTTTCAAAGTGGAATACTGCAGGACGT
TTTCTAAGCTGCCTGTACGGCAGTG	GACAGGAGGAACTTATGGCAATTTTAGTGGAAGCT
TTTCTAAGCTGCCTGTACGGCATTG	AACGGCAATGGTCCGGACGGTCGCCCTGAATTCCA
TTTCTAAGCTGCCTGTACGGCAGTGAACTTAGGTGGCGGGGTGATGGAGGATGTGTCGGTTTTCTAAGCTGCCTGTACGGCAGTGAACGTGGATGGTCCTCGCGCCCTCTGGTGTTGTTTTTTTCTAAGCTGCCTGTACGGCAGTGAAC	GGGTAATACCCATCAAAGGGGCGAGCA
CGTATTTTCTAAGCTGCCTGTACGGCAGTGAAC	AAGGCATTCAAAAGCCTGTAAGGGGAC
GTTATTTTCTAAGCTGCCTGTACGGCAGTGAAC	GCAAGGGATGGCAAAAGTGATGGCGTC


>NZ_CP022148|1|1|2017910-2018539|CRISPRCasFinder
TTTCTAAGCTGCCTGTACGACAGTGAAC	TAGTCGGCCTTCTTTTGGCGGCAAGCCACAGA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GCTCGTCACCAGGGTTAACTGATTTGTCGGAAT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	TTACCGTTTCAAAGTGGAATACTGCAGGACGT
TTTCTAAGCTGCCTGTACGGCAGTGGAC	AGGAGGAACTTATGGCAATTTTAGTGGAAGCT
TTTCTAAGCTGCCTGTACGGCATTGAAC	GGCAATGGTCCGGACGGTCGCCCTGAATTCCA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	TTAGGTGGCGGGGTGATGGAGGATGTGTCGGT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GTGGATGGTCCTCGCGCCCTCTGGTGTTGTTTT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GGGTAATACCCATCAAAGGGGCGAGCACGTAT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	AAGGCATTCAAAAGCCTGTAAGGGGACGTTAT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GCAAGGGATGGCAAAAGTGATGGCGTCGTTCG
TTTCTAAGCTGCCTGTACGGCAGTGAAC

>NZ_CP022148|1|1|2017910-2018539|CRT
TTTCTAAGCTGCCTGTACGACAGTGAAC	TAGTCGGCCTTCTTTTGGCGGCAAGCCACAGA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GCTCGTCACCAGGGTTAACTGATTTGTCGGAAT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	TTACCGTTTCAAAGTGGAATACTGCAGGACGT
TTTCTAAGCTGCCTGTACGGCAGTGGAC	AGGAGGAACTTATGGCAATTTTAGTGGAAGCT
TTTCTAAGCTGCCTGTACGGCATTGAAC	GGCAATGGTCCGGACGGTCGCCCTGAATTCCA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	TTAGGTGGCGGGGTGATGGAGGATGTGTCGGT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GTGGATGGTCCTCGCGCCCTCTGGTGTTGTTTT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GGGTAATACCCATCAAAGGGGCGAGCACGTAT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	AAGGCATTCAAAAGCCTGTAAGGGGACGTTAT
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GCAAGGGATGGCAAAAGTGATGGCGTCGTTCG
TTTCTAAGCTGCCTGTACGGCAGTGAAC

>NZ_CP022148|1|2|2018327-2018539|PILER-CR
	AACTAGTCGGCCTTCTTTTGGCGGCAAGCCACAGA
TTTCTAAGCTGCCTGTACGGCAGTG	AACGCTCGTCACCAGGGTTAACTGATTTGTCGGAAT
TTTCTAAGCTGCCTGTACGGCAGTG	AACTTACCGTTTCAAAGTGGAATACTGCAGGACGT
TTTCTAAGCTGCCTGTACGGCAGTG	GACAGGAGGAACTTATGGCAATTTTAGTGGAAGCT
TTTCTAAGCTGCCTGTACGGCATTG	AACGGCAATGGTCCGGACGGTCGCCCTGAATTCCA
TTTCTAAGCTGCCTGTACGGCAGTGAACTTAGGTGGCGGGGTGATGGAGGATGTGTCGGTTTTCTAAGCTGCCTGTACGGCAGTGAACGTGGATGGTCCTCGCGCCCTCTGGTGTTGTTTTTTTCTAAGCTGCCTGTACGGCAGTGAAC	GGGTAATACCCATCAAAGGGGCGAGCA
CGTATTTTCTAAGCTGCCTGTACGGCAGTGAAC	AAGGCATTCAAAAGCCTGTAAGGGGAC
GTTATTTTCTAAGCTGCCTGTACGGCAGTGAAC	GCAAGGGATGGCAAAAGTGATGGCGTC
GTTCGTTTCTAAGCTGCCTGTACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022148.1\|WP_021240893.1\|2011272_2012931_-\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NZ_CP022148.1\|WP_023327007.1\|2009044_2010160_-\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NZ_CP022148.1\|WP_023343670.1\|2019290_2021009_+\|ubiquinone-dependent-pyruvate-dehydrogenase	unknown	unknown	gnl\|CDD\|181661
NZ_CP022148.1\|WP_008500006.1\|2023588_2024602_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528
NZ_CP022148.1\|WP_063418443.1\|2022059_2023496_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187556
NZ_CP022148.1\|WP_021240900.1\|2021047_2022049_+\|low-specificity-L-threonine-aldolase	unknown	unknown	gnl\|CDD\|236710
NZ_CP022148.1\|WP_063418442.1\|2016794_2017763_+\|NADH-oxidoreductase	unknown	unknown	gnl\|CDD\|236735
NZ_CP022148.1\|WP_063418441.1\|2014087_2014987_+\|lysine-exporter-LysO-family-protein	unknown	unknown	gnl\|CDD\|225287
NZ_CP022148.1\|WP_023292896.1\|2010319_2011276_+\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|377343
NZ_CP022148.1\|WP_008499994.1\|2007107_2009048_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NZ_CP022148.1\|WP_063418445.1\|2027295_2030007_-\|glycoside-hydrolase	unknown	unknown	gnl\|CDD\|119365
NZ_CP022148.1\|WP_063418202.1\|2031058_2031544_-\|type-II-secretion-system-protein-M	unknown	unknown	gnl\|CDD\|377391
NZ_CP022148.1\|WP_063418203.1\|2030264_2031062_-\|prepilin-peptidase	unknown	unknown	gnl\|CDD\|224900
NZ_CP022148.1\|WP_006174393.1\|2006227_2006548_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP022148.1\|WP_039266063.1\|2018704_2019139_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|311556
NZ_CP022148.1\|WP_063418446.1\|2013221_2013917_+\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NZ_CP022148.1\|WP_008499993.1\|2006815_2007037_+\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|184960
NZ_CP022148.1\|WP_008500008.1\|2026724_2027159_-\|type-III-secretion-system-invasion-protein-IagB	unknown	unknown	gnl\|CDD\|185228
NZ_CP022148.1\|WP_049122658.1\|2015131_2016784_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NZ_CP022148.1\|WP_063418444.1\|2024762_2026574_-\|chitinase	unknown	unknown	gnl\|CDD\|381595

Protein	Function_ID	Function_description	E-value
NZ_CP022148.1\|WP_021240893.1\|2011272_2012931_-\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NZ_CP022148.1\|WP_023327007.1\|2009044_2010160_-\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NZ_CP022148.1\|WP_023343670.1\|2019290_2021009_+\|ubiquinone-dependent-pyruvate-dehydrogenase	gnl\|CDD\|181661	PRK09124, PRK09124, ubiquinone-dependent pyruvate dehydrogenase.	0
NZ_CP022148.1\|WP_008500006.1\|2023588_2024602_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	6.20693e-53
NZ_CP022148.1\|WP_063418443.1\|2022059_2023496_+\|SDR-family-oxidoreductase	gnl\|CDD\|187556	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2. This subgroup contains atypical SDRs, one member is identified as Escherichia coli protein ybjT, function unknown. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that generally matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.71043e-141
NZ_CP022148.1\|WP_021240900.1\|2021047_2022049_+\|low-specificity-L-threonine-aldolase	gnl\|CDD\|236710	PRK10534, PRK10534, L-threonine aldolase; Provisional.	0
NZ_CP022148.1\|WP_063418442.1\|2016794_2017763_+\|NADH-oxidoreductase	gnl\|CDD\|236735	PRK10684, PRK10684, HCP oxidoreductase, NADH-dependent; Provisional.	0
NZ_CP022148.1\|WP_063418441.1\|2014087_2014987_+\|lysine-exporter-LysO-family-protein	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	8.43683e-114
NZ_CP022148.1\|WP_023292896.1\|2010319_2011276_+\|DUF535-domain-containing-protein	gnl\|CDD\|377343	pfam04393, DUF535, Protein of unknown function (DUF535). Family member Shigella flexneri VirK is a virulence protein required for the expression, or correct membrane localization of IcsA (VirG) on the bacterial cell surface,. This family also includes Pasteurella haemolytica lapB, which is thought to be membrane-associated.	1.68223e-121
NZ_CP022148.1\|WP_008499994.1\|2007107_2009048_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NZ_CP022148.1\|WP_063418445.1\|2027295_2030007_-\|glycoside-hydrolase	gnl\|CDD\|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	8.46689e-126
NZ_CP022148.1\|WP_063418202.1\|2031058_2031544_-\|type-II-secretion-system-protein-M	gnl\|CDD\|377391	pfam04612, T2SSM, Type II secretion system (T2SS), protein M. This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.	1.97236e-28
NZ_CP022148.1\|WP_063418203.1\|2030264_2031062_-\|prepilin-peptidase	gnl\|CDD\|224900	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	7.7292e-43
NZ_CP022148.1\|WP_006174393.1\|2006227_2006548_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	9.90991e-48
NZ_CP022148.1\|WP_039266063.1\|2018704_2019139_-\|DoxX-family-protein	gnl\|CDD\|311556	pfam07681, DoxX, DoxX. These proteins appear to have some sequence similarity with pfam04173 but their function is unknown.	5.05523e-12
NZ_CP022148.1\|WP_063418446.1\|2013221_2013917_+\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	1.98843e-146
NZ_CP022148.1\|WP_008499993.1\|2006815_2007037_+\|cold-shock-like-protein-CspD	gnl\|CDD\|184960	PRK14998, PRK14998, cold shock-like protein CspD; Provisional.	6.50125e-48
NZ_CP022148.1\|WP_008500008.1\|2026724_2027159_-\|type-III-secretion-system-invasion-protein-IagB	gnl\|CDD\|185228	PRK15328, PRK15328, type III secretion system invasion protein IagB.	2.16696e-85
NZ_CP022148.1\|WP_049122658.1\|2015131_2016784_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NZ_CP022148.1\|WP_063418444.1\|2024762_2026574_-\|chitinase	gnl\|CDD\|381595	cd00325, chitinase_GH19, Glycoside hydrolase family 19, chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Glycoside hydrolase family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases, but they are smaller in size due to certain deletions. Despite lacking any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the prokaryotic/eukaryotic divergence.	7.86767e-71

>NZ_CP022148.1|WP_063418442.1|2016794_2017763_+|NADH-oxidoreductase
MTMPTSQCPWRMQVHHIHQETPDVWTLSLLCHDYYPYRAGQYALVSVRHSADTLRAYTLSSTPGVSEYITLTVRRIDDGAGSQWLTRDVKRGDYIWLSDAQGDFTCDDKADDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVQVIFSVRSPDDVIFAEEWRDYPVTLVAEHNATHGFVPGRLSRELLQSVPDIANRTVMTCGPAPYMAIVEEEVKALGVTRFFKEQFFTPVAEAATSGIQFTKLQPAQTFFGRVGTTLLEALESNNVPVAAACRAGVCGCCKTKVVSGEYTVTSTMTLSDAEIAEGYVLACSCHPQGDLVLA
>NZ_CP022148.1|WP_049122658.1|2015131_2016784_+|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWACKAREYGIVDHYVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCMKADANARVENPMSDLQLVSDDLGDLQRQAAEFTPNKDKAAIGDNILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFRVMSILDAGETGTYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLKQTEGTGVNVYTHGEMLPAHGYPELRKFKHLIGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHLITVGFGRETLLGAADSLIDLVSREKLRHIFLVGGCDGARGERNYFTDFATRVPEDCLILTLACGKYRFNKLDFGNIEGLPRLIDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVTNIVTGPTAPGFLTPDLLAVLNEKFGLRSVTNVEDDMKQLLSA
>NZ_CP022148.1|WP_063418441.1|2014087_2014987_+|lysine-exporter-LysO-family-protein
MFSGLLIILLPLIAGYLIPLHRESALRLINRFLSWIVYVILFFMGISLAFLDNLATNLLSILHYSVVTVVVILLCNIAALFWLERTVPWKNHHHQEKLPSRIAMALESLKLCGVVVLGFLLGLTGWAFLQHATEASEYTLIFLLFLIGIQLRNNGMTLKQIVLNRRGMMVAVIVISSSMVAGVINAFILDLPLKTGLAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELLAIMLIPGLVRRSRSTALGLCGATSMDFTLPVLQRSGGLEMVPAAIVHGFILSLLVPVLMAVFSA
>NZ_CP022148.1|WP_063418446.1|2013221_2013917_+|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAAFPELGIGFVGVALAFGLTVLTMAFAVGHISGGHFNPAVTLGLWAGGRFPAKEVIGYIVAQVVGGIIAAGVLYVIASGKAGFDAAASGFASNGFGEHSPGGYSMLSAIVIEIVLTAGFLLVIHGATDKQAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWLFWVMPIIGGILGGVLYRTLLEKRD
>NZ_CP022148.1|WP_021240893.1|2011272_2012931_-|ATP-dependent-endonuclease
MLLERVEIVGFRGINRLSLQLEQNNVLIGENAWGKSSLLDALTLLLSPEDDLYHFVRDDFWFPPGDVTGREKHLHIILTFRESEPGRHRVRRFRPLSPCWVPCDDGFHRIFYRLEGEMAENEGVLTLRDFLDEKASPIPLDNIDDLARHLIRLTPVLRLRDARFMRRIRNGTVPNMPEVEVTARELDFLARELVSRPQNLTDGQIRQGLSAMVQLLEHYFSEQGTSESRHRLMRRRSHDEQRSWRYLDIINRMIDRPGGRTHRVILLGLFSTLLQAKGTVRLDRDARPLLLVEDPETRLHPIMLSVAWHLLNLLPLQRVTTTNSGELLSLTPVEHVCRLVRESSRVSAFRLGPGGLNAEDGRRIAFHIRFNRASSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLIKFARRMGIEWHVLVDGDEAGKKYASTVRSLLNNEREEERDHLTMLPAMDMEHFMYRQGFDDVFHRIAMVPVDVPMNMRRVIAKAIHRSSKPDLAIEVATEAGRRGVEAVPTLLRKMFSRVLWLARGRAD
>NZ_CP022148.1|WP_023292896.1|2010319_2011276_+|DUF535-domain-containing-protein
MSSIVDTPFSNLPQPASGWQLFSHLASGKLTPGLAWQNPAYRRKFMLRSLATPVSTARLLTSLAKQPSLMQMLQVQPGLPCRLHRPWLTVNMDRQQALESLNWHYQTMSRHMPASLLSGYLSKKGFTLLTLTGKDEEQFTVRLCADAFLDKEGEATLAFCDHQNTVLAEMTFTLCQLEGKSTLFIGGLQGAKAHVPHELIQGATKACHGLFPKRLLVEAAMTLGTAFPVEQIVAVSNDTHIYRSWRYRKKKEGKLLADYDSFWISIGGEKQDSGNFMLPLVMPRKPMEEIASKKRSEYRRRYALLDSLIQQVNQATQR
>NZ_CP022148.1|WP_023327007.1|2009044_2010160_-|macrolide-transporter-subunit-MacA
MNLKGKRRTLFLLLAVVVLAGGYWLWQVLNAPVPQYQTLIVRPGELQQNVLATGKLDALRKVDVGAQVSGQLKTLSVEIGDKVKKGQLLGVIDPEQAENQIREVEATLMELRAQRAQAQAERNLAQVTLTRQQALAKTQAISKQDLDTATTELAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTKIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRPGQNAWFTVLGDPQTRYEGVLKDILPTPEKVNDAIFYYARFEVPNPQGVLRLDMTAQVHIQLTGVKNVLTIPLSALGESAGDSRYKVKVLRNGETREREVVIGARNDTDVVVVKGLEEGEEVVISESLPGAAK
>NZ_CP022148.1|WP_008499994.1|2007107_2009048_-|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTALLELKDIRRSYPSGDGPVEVLKGISLRVEAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGTDVSTLDGDALAKLRREHFGFIFQRYHLLSHLNAAQNVEVPAVYAGVERKKRLERAQMLLTRLGLAERVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDQGHTVIIVTHDPQVAAQAERIIEIHDGELVSNPPPRESRAAAPKEVLPASTGWGQFSSGFREALTMAWLAMAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQLVLADIRAIGTNTIDVYPGKDFGDDEPQYQQALKYDDLAAIQKQPWVNSATPAVSQNLRLRVGNVDVAASANGVSGDYFNVYGMTFSEGATFNAEQLAGRAQVVVLDANSRRQLFPNKANVVGEVILVGNMPATVIGVAEEKQSMFGSSKILRVWLPYTTISGRIMGQSWLNSITVRVKEGYDSAMAEQQLERLLTLRHGKKDFFTWNMDGLLKTAEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGAMGIALSMMIAFALQLFLPGWEIGFSPVAIITAFLCSTFTGILFGWLPARNAARLDPVDALARE
>NZ_CP022148.1|WP_008499993.1|2006815_2007037_+|cold-shock-like-protein-CspD
MEMGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVRFDVHQGPKGNHASLIVPIEAETVA
>NZ_CP022148.1|WP_006174393.1|2006227_2006548_-|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEDKVRDALKPPSMYKVMLMNDDYTPMEFVIDVLQKFFSYDVERATQLMLTVHYRGKAICGIFTAEVAETKVAMVNDYARENEHPLLCTLEKA
>NZ_CP022148.1|WP_039266063.1|2018704_2019139_-|DoxX-family-protein
MVKSLLIAVNEKLSCDDLGKLLLRLAVGGLMLFHGLHKLFGGVGFISGMLVEKGLPGFIAYGVLIGEVVAPILIIVGLFTRPAALVLAFTMIVAWLMVGLDETFALDKVGAWAIESLVYFFIGSLAVAFLGAGRFALGKTPAWR
>NZ_CP022148.1|WP_023343670.1|2019290_2021009_+|ubiquinone-dependent-pyruvate-dehydrogenase
MKQTVAAYIAKTLEQAGVKRIWGVTGDSLNGLSDSLNKMKTIEWMPTRHEEVAAFAAGAEAQLTGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVIPGDVALKAAPEGASTHWYHAPQPVVTPAEEELKKLAQLLRYASNIALMCGSGCAGAHKELLEFAGKLKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLILLGTQFPYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLAALLPLLEEKTDRKFLDKALSDYRDARKGLDDLAKPSDKAIHPQYLAQQISHFADDDAIFTCDVGTPTVWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAKATAPERQVVAMCGDGGFSMLMGDFLSVVQMKLPLKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELAKTNWLR
>NZ_CP022148.1|WP_021240900.1|2021047_2022049_+|low-specificity-L-threonine-aldolase
MIDLRSDTVTRPSRAMLEEMMAAPVGDDVYGDDPTVNELQRYAAELSGKEAALFLPTGTQANLVALLSHCERGEEYIVGQGAHNYLYEAGGAAVLGSIQPQPIDAAPDGTLPLDKVAAKIKADDIHFARTRLLSLENTHNGKVLPREYLKAAWEFTRERGLGLHVDGARIFNAVVEYGCALKEITQYCDSFTICLSKGLGTPVGSLLVGNADYIKRANRWRKMTGGGMRQAGILAAAGLYALKNNVARLKDDHDNAAWMAAQLREIGADVMRHDTNMLFVRVGDDHAAALGEFMKARGVLINASPVVRLVMHLDVNREQLADVVKHWQAFLQR
>NZ_CP022148.1|WP_063418443.1|2022059_2023496_+|SDR-family-oxidoreductase
MPQRILVLGASGYIGQHLTAALSQQGHQVLAAARNTERLQKLGLPGVTCHNVDLNWPKALPALLEGVDTLYYLVHSMGEGGDFIAHERQVAMNVRDALLQTPVKQVIFLSSLQAPEREQSDHLRARQLTADILRGANIPVTELRAGIIVGAGSAAFEVMRDMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPAEQHRVLEAAGPEVLSYQAQFEHFMRVSGRRRWLIPIPFPTRWISVWFLNVITSVPPTTAKALIQGLKHDLLADDRALRALIPQDLIRFDDAVRNTLKEEEQLVNSSDWGYDAQAFARWRPEYGYYPKQAGCTVKTSASLAALWEVVNQIGGKERYFFGNLLWQTRGAMDLLVGHRLAKGRPARPYLEVGDAVDSWKVIIVEPEKQLALLFGMKAPGLGRLCFTLKDKGDHRELDVRAWWHPHGMPGLFYWLLMIPAHLFIFRGMAKRIAQRAEQKTEKI
>NZ_CP022148.1|WP_008500006.1|2023588_2024602_+|NAD(P)-dependent-oxidoreductase
MKVLVTGATSGLGRNAVEFLRNKGISVRATGRNEAMGKLLQKMGAEFVHADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQEAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFDYHHHRDVQEDFRPARFACEFARSKAASEEVIDLLAQSNPHTRFTVLRPQSLFGPHDKVFIPRLAQMMHHYGSVLLPRGGDALVDMTYYENAVHAMWLASQPDCDKLISGRAYNITNGEPCTLRSIVQRLIDELQINCRIRSVPYPMLDMIARSMERFGSKTAKEPALTHYGVSKLNFDFTLDISRAENELGYKPVVTLDEGIMRTAAWLRDHGKLHR
>NZ_CP022148.1|WP_063418444.1|2024762_2026574_-|chitinase
MTKRTLLSVLVAGACIAPFMAQAASLQAASSEPYTMKASDLAKKEKELTNFPLMVSVKDTIATLDNSLVEQIEPGRASNPDNVKRVEGIVKASDWEYLFPLRAQSYTYSNFLKAVGKFPALCKTYNDGRDSDAICRKELATMFAHFAQETGGHESWRPEAEWRQALVHVREMGWTEGQKGGYNGECNPDIWQGQTWPCGKDKDGDFVSYFGRGAKQLSYNYNYGPFSEAMFGTVRTLLDKPELVADTWLNLASAIFFFAYPQPPKPSMLQVIDGTWQPNDHDKANGLVPGFGVTTQIINGGVECGGPTEIAQSENRIKYYKEFANYLKVPVPANEVLGCANMKQFDEGGAGALKIYWEQDWGWSPDTPDGKTYSCQLVGYQTPFSAFKEGDYTNCVKKFYNVNIINDDGSAVTPGEDKTPADTTPPADTMPAEDTTPVEPATVNHAPVAQIAGPIGAVEAGAQVSLSAEGSTDADGNKLTYTWRSQDGQTVTGQDKAVVTFKAPESATAQQYEIGLTVSDGELTSTTSYLLNVKAKAESKDEGTSGSYAAWSANSKYNAGDIVNNHGKLFQCKPFPYSGWCNNAPAYYEPGAGLAWADAWTAL
>NZ_CP022148.1|WP_008500008.1|2026724_2027159_-|type-III-secretion-system-invasion-protein-IagB
MKRVIIFLLLFSQSVFANCWDNAGHYYHVDPWLLYAIAKVESGMNPHAVGWNHDGTRDVGLMQINSSHFSELERQGIDENQLINEPCTSIMVGASILSGMINVYGYNWEAVGAYNAGLKKENYPQRMRYAHKVWAKYQQIKSGK
>NZ_CP022148.1|WP_063418445.1|2027295_2030007_-|glycoside-hydrolase
MKFIKPKYLALFIAAATGSAFAAAPGAPTIASGNDKFALVEVDQAAQDYNSLVKVHNDGVDVKVEWNVWSGDAPTSAKVLLDGKTVWTGAAGASGSATFKVKKGGRYQEQVEVCNASGCTKSASKLIIVADTDGSHLLPLNAPLQENNKTFAKHTDKVVAAYFPEWGVYDRNFPVDKIPAANLNHILYGFIPICGGDGINDGLKTVEGGNSFSVLQRDCAGRPDYTVAIHDPWAALQKPQSGVSNWDDPYKGNFGQLMALKKAHPDLKVLPSIGGWTLSDPFFHMGDPAIRARFVSSVKDFLQTWKFFDGVDIDWEFPGGGGVSEHLGNPQQDKATYTALMHDLRTMLNELSAQTGRTYELTSAIGAGRDKIEDVDYTAAQQYLDHIFLMSYDFYGGWSNTELGHQAALRAPSWRPDTNYTTENGVDALLAQGVQPGKIVVGAGMYGRGWTGVHGYTGDNPFTGTATGMVKGTWEPGVVDYRQIVNEYKGKPGWEYGYDANAEAPYVFNKSTGDLITYEDARSTAAKGKYVLSKNLGGLFAWSIDSDTGDILNAMNESLLGGSTPVDPVVTNHAPIASSADQNVSGPATVTLDGSASSDPDGDAITYKWTQVSGPSVTLSNSTKAKATFNVAAATSDQTMVFRLTVTDAKGLSNAIDVQVVNKAPKANQAPVVNAMEAVTLQAGETYALHAQAVDPDGDAMTFSWSVPADMHATGTDTANVTITAPDVATTSTYTLSVVVGDGKTSVQSNVQVTVNPKPADVTPPSDDVTPPSDEVTPPSDDVTPPSDEGSATGSCDAPVDANASKYAAWDGSKIYNSGDTVSFDHLVWKAKYWTQGNQPGFGVDAWELVSNVKMNWRSDLVYNGGETTTYQGNVYRAKWWTRGDNPANSDVWVKEGPSTDCK
>NZ_CP022148.1|WP_063418203.1|2030264_2031062_-|prepilin-peptidase
MNGLILVRESYPVGFAAMSGVFGAILGSFLGVVVDRVPGMVLEEESRSNLLFPASHCPVCQHALRAWENIPLLSWLALRGRCRCCKSPIPLRLFLLELLTAVFFGLTARWIPDLASLFSLWVLAAFLLPLAMIDGQHQLLPDCLTQPLLWAGLLFHAFSHGLPLRDALLGAVAGYLSLWLVYWAFRLLTRREGLGYGDFKLLAALGAWCGWQSLPAIELIAALSGIVGYLLLNKSNKNNLTIAFGPYLAFAGIALYTYQLFVNTY
>NZ_CP022148.1|WP_063418202.1|2031058_2031544_-|type-II-secretion-system-protein-M
MKARIAQFTSRYQQYSAREKFILKIAAGALCSAVIYYAGIIPLDNMIKNSQATLARQIETVNWMKTEIDKNHLPVLQVKTDNPRSVVENSAHEINLTLTDIRQDGQTLAFVVNRVNVYKLKNWLREMNLASGVRLEKMNLTPVDHLSDVKAEIQLTWKKVA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022148_1	1.9\|2018119\|32\|NZ_CP022148\|CRISPRCasFinder,CRT	2018119-2018150	32	NZ_CP015507	Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence	339556-339587	7	0.781
NZ_CP022148_1	1.15\|2018480\|32\|NZ_CP022148\|CRISPRCasFinder,CRT	2018480-2018511	32	KC292029	Halovirus HCTV-1, complete genome	60196-60227	7	0.781
NZ_CP022148_1	1.10\|2018179\|32\|NZ_CP022148\|CRISPRCasFinder,CRT	2018179-2018210	32	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	1463327-1463358	9	0.719
NZ_CP022148_1	1.10\|2018179\|32\|NZ_CP022148\|CRISPRCasFinder,CRT	2018179-2018210	32	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	1378036-1378067	9	0.719
NZ_CP022148_1	1.14\|2018420\|32\|NZ_CP022148\|CRISPRCasFinder,CRT	2018420-2018451	32	NZ_CP033514	Vibrio cholerae strain E4 plasmid pVCR94, complete sequence	50380-50411	10	0.688
NZ_CP022148_1	1.14\|2018420\|32\|NZ_CP022148\|CRISPRCasFinder,CRT	2018420-2018451	32	NC_023291	Vibrio cholerae strain BI144 plasmid pVCR94deltaX, complete sequence	73513-73544	10	0.688

1. spacer 1.9|2018119|32|NZ_CP022148|CRISPRCasFinder,CRT matches to NZ_CP015507 (Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence) position: , mismatch: 7, identity: 0.781

aggaggaacttatggcaattttagtggaagct---	CRISPR spacer
aggaggcacttatgtcaattttaat---aacttgg	Protospacer
****** ******* ********.*   *.**

2. spacer 1.15|2018480|32|NZ_CP022148|CRISPRCasFinder,CRT matches to KC292029 (Halovirus HCTV-1, complete genome) position: , mismatch: 7, identity: 0.781

--gcaagggatggcaaaagtgatggcgtcgttcg	CRISPR spacer
cgacaacga--ggcgaaagtgatggtgtcgttcg	Protospacer
  .*** *.  ***.**********.********

3. spacer 1.10|2018179|32|NZ_CP022148|CRISPRCasFinder,CRT matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 9, identity: 0.719

ggcaatggtccggacggtcgccctgaattcca	CRISPR spacer
ggcaatggtccggtcggccgcccatttgctca	Protospacer
************* ***.*****     ..**

4. spacer 1.10|2018179|32|NZ_CP022148|CRISPRCasFinder,CRT matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 9, identity: 0.719

ggcaatggtccggacggtcgccctgaattcca	CRISPR spacer
ggcaatggtccggtcggccgcccacttgctca	Protospacer
************* ***.*****     ..**

5. spacer 1.14|2018420|32|NZ_CP022148|CRISPRCasFinder,CRT matches to NZ_CP033514 (Vibrio cholerae strain E4 plasmid pVCR94, complete sequence) position: , mismatch: 10, identity: 0.688

aaggcattcaaaagcctgtaaggggacgttat	CRISPR spacer
gctgttggcaaaagcctggtaggggacgttaa	Protospacer
.  *.   **********  ***********

6. spacer 1.14|2018420|32|NZ_CP022148|CRISPRCasFinder,CRT matches to NC_023291 (Vibrio cholerae strain BI144 plasmid pVCR94deltaX, complete sequence) position: , mismatch: 10, identity: 0.688

aaggcattcaaaagcctgtaaggggacgttat	CRISPR spacer
gctgttggcaaaagcctggtaggggacgttaa	Protospacer
.  *.   **********  ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

372538 : 381906

Enterobacteria_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023325626.1\|372538_373930_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	1.8e-18	32.3
WP_039266717.1\|374106_375000_+	GalU regulator GalF	A0A127AW70	Bacillus_phage	9.0e-43	42.2
WP_063417350.1\|375385_376474_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.3e-91	48.6
WP_063417351.1\|376488_377355_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.4e-109	66.7
WP_074166936.1\|377376_378267_+	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	5.6e-29	36.3
WP_165602155.1\|378345_379272_+	glycosyltransferase	NA	NA	NA	NA
WP_063417352.1\|379275_380043_+	ABC transporter permease	NA	NA	NA	NA
WP_063417353.1\|380042_380783_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.5e-16	30.2
WP_063417354.1\|380790_381906_+	DegT/DnrJ/EryC1/StrS family aminotransferase	E5ERI7	Ostreococcus_lucimarinus_virus	2.4e-13	23.5

DBSCAN-SWA_2

493647 : 535470

Salmonella_phage(43.18%)

integrase,tail

attL 502328:502343|attR 510607:510622

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088728336.1\|493647_494658_-\|integrase	tyrosine-type recombinase/integrase	K7PLZ2	Enterobacterial_phage	2.5e-126	64.3
WP_045326850.1\|494657_494885_-	DUF4224 domain-containing protein	K7PHA0	Enterobacterial_phage	1.9e-10	45.0
WP_088728337.1\|495123_495456_-	hypothetical protein	NA	NA	NA	NA
WP_088728338.1\|495448_495805_-	hypothetical protein	NA	NA	NA	NA
WP_088728340.1\|495923_496361_-	hypothetical protein	NA	NA	NA	NA
WP_088728487.1\|496332_496710_-	restriction alleviation protein, Lar family	NA	NA	NA	NA
WP_088728341.1\|496739_497537_-	ORF6N domain-containing protein	F1C5A3	Cronobacter_phage	8.8e-50	70.9
WP_088728342.1\|497549_498053_-	hypothetical protein	F1C5A2	Cronobacter_phage	4.6e-52	60.5
WP_088728343.1\|498079_498409_-	hypothetical protein	A0A1B5FPB3	Escherichia_phage	4.0e-33	69.3
WP_044596881.1\|498401_498623_-	hypothetical protein	NA	NA	NA	NA
WP_088728344.1\|498729_499116_-	S24 family peptidase	F1C5A0	Cronobacter_phage	2.4e-37	60.0
WP_088728345.1\|499178_499397_-	hypothetical protein	NA	NA	NA	NA
WP_088728346.1\|499396_499609_-	hypothetical protein	NA	NA	NA	NA
WP_058672940.1\|499806_500472_-	LexA family transcriptional regulator	C6ZR47	Salmonella_phage	4.0e-72	57.5
WP_058672939.1\|500580_500793_+	helix-turn-helix transcriptional regulator	A0A0N7C2U7	Escherichia_phage	3.5e-14	54.5
WP_088728347.1\|500794_501004_+	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_088728348.1\|500996_502019_+	hypothetical protein	V5URT9	Shigella_phage	1.4e-47	56.3
WP_088728349.1\|502122_503994_+	AAA family ATPase	Q5G8S8	Enterobacteria_phage	6.4e-224	59.7
502328:502343	attL	NA	NA	NA	NA
WP_088728350.1\|503997_504801_+	antitermination protein	F1C595	Cronobacter_phage	1.7e-104	71.9
WP_088728351.1\|504932_505484_+	hypothetical protein	B5WZS6	Pseudomonas_phage	2.6e-40	45.2
WP_060569213.1\|505543_505864_+	hypothetical protein	H6WRZ3	Salmonella_phage	1.4e-38	78.8
WP_165769319.1\|505856_506372_+	lysozyme	I6PBN2	Cronobacter_phage	1.3e-49	62.0
WP_088728353.1\|506368_506914_+	hypothetical protein	K7P6W1	Enterobacteria_phage	9.6e-48	67.8
WP_133063757.1\|506982_507234_-	hypothetical protein	NA	NA	NA	NA
WP_088728355.1\|507415_508420_+\|integrase	tyrosine-type recombinase/integrase	Q9T1Z2	Lactococcus_phage	3.4e-06	24.7
WP_088728356.1\|508666_509269_+	hypothetical protein	NA	NA	NA	NA
WP_088728357.1\|509467_511084_+	TerL protein	A0A0M5M1R6	Salmonella_phage	8.1e-268	80.4
510607:510622	attR	NA	NA	NA	NA
WP_088728358.1\|511085_512555_+	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	6.2e-158	56.5
WP_016247462.1\|512625_513159_+	hypothetical protein	A0A0M4REK0	Salmonella_phage	1.7e-49	57.5
WP_088728359.1\|513420_514692_+	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	5.0e-79	41.5
WP_088728360.1\|514703_515207_+	hypothetical protein	A0A0M4QWZ6	Salmonella_phage	2.9e-30	47.0
WP_088728361.1\|515218_516166_+	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	8.5e-108	60.1
WP_088728362.1\|516211_516622_+	hypothetical protein	NA	NA	NA	NA
WP_023150225.1\|516593_517004_+	DUF4054 domain-containing protein	A0A2H4J1A6	uncultured_Caudovirales_phage	4.4e-29	51.9
WP_088728363.1\|517000_517507_+	hypothetical protein	NA	NA	NA	NA
WP_016247455.1\|517506_517911_+	hypothetical protein	A0A2H4J1A4	uncultured_Caudovirales_phage	1.4e-43	70.0
WP_088728364.1\|517903_518449_+	hypothetical protein	A0A2H4J1A0	uncultured_Caudovirales_phage	8.2e-47	49.7
WP_088728365.1\|518452_519598_+	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	2.7e-164	75.6
WP_000257260.1\|519609_520050_+	DUF3277 family protein	A0A2H4J619	uncultured_Caudovirales_phage	2.0e-56	74.7
WP_088728366.1\|520053_520506_+	hypothetical protein	A0A0M4S6U8	Salmonella_phage	7.4e-62	79.3
WP_088728367.1\|520683_522693_+	transglycosylase SLT domain-containing protein	A0A0M4REK7	Salmonella_phage	0.0e+00	96.0
WP_016247449.1\|522692_523280_+	hypothetical protein	A0A0M3ULD5	Salmonella_phage	1.3e-87	90.3
WP_088728368.1\|523279_523582_+	hypothetical protein	A0A0M4R5B7	Salmonella_phage	9.7e-50	94.0
WP_088728369.1\|523584_524649_+	hypothetical protein	A0A0M4QX01	Salmonella_phage	5.5e-156	79.4
WP_088728370.1\|524648_524981_+	hypothetical protein	A0A0M4RTY3	Salmonella_phage	3.8e-23	70.9
WP_063418408.1\|525074_525848_+	hypothetical protein	NA	NA	NA	NA
WP_063418407.1\|525834_526230_+	hypothetical protein	NA	NA	NA	NA
WP_087449653.1\|526291_527044_+	translation initiation factor IF-2	A0A0M5M1K7	Salmonella_phage	1.2e-91	69.8
WP_023325694.1\|527043_527397_+	hypothetical protein	A0A0M4R339	Salmonella_phage	5.1e-58	94.9
WP_088728371.1\|527397_528597_+	hypothetical protein	A0A0M4RD32	Salmonella_phage	5.4e-184	84.5
WP_023325692.1\|528593_529274_+	DUF2612 domain-containing protein	A0A0M5M1K4	Salmonella_phage	3.8e-110	82.3
WP_088728488.1\|529998_530502_+\|tail	tail fiber assembly protein	U5P0S4	Shigella_phage	3.5e-20	69.6
WP_088728372.1\|530473_530881_-\|tail	phage tail protein	U5P083	Shigella_phage	3.7e-20	48.5
WP_133063758.1\|530880_531213_-	hypothetical protein	NA	NA	NA	NA
WP_023325687.1\|531242_531797_+	recombinase family protein	A0A1S6L009	Salmonella_phage	3.4e-85	87.3
WP_088728373.1\|531846_532113_-	DinI family protein	K7PKR6	Enterobacteria_phage	1.8e-39	93.2
WP_088728374.1\|532123_532393_-	hypothetical protein	A0A0M3ULK3	Salmonella_phage	7.9e-19	54.2
WP_063417231.1\|532926_533604_+	DUF2076 domain-containing protein	NA	NA	NA	NA
WP_159427218.1\|533715_533880_-	hypothetical protein	NA	NA	NA	NA
WP_025912270.1\|533881_534598_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.6e-12	26.0
WP_021240464.1\|534594_535470_-	ATP-binding cassette domain-containing protein	A0A285PWH2	Cedratvirus	6.2e-12	25.5

DBSCAN-SWA_3

609905 : 660655

Cronobacter_phage(17.95%)

integrase,transposase,tail,terminase

attL 609337:609364|attR 661849:661876

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
609337:609364	attL	NA	NA	NA	NA
WP_016947617.1\|609905_610886_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	98.8
WP_165769316.1\|610867_611899_+	hypothetical protein	NA	NA	NA	NA
WP_063417214.1\|611900_612323_+	hypothetical protein	NA	NA	NA	NA
WP_063417213.1\|612322_613210_+	hypothetical protein	NA	NA	NA	NA
WP_063417243.1\|613244_614312_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	1.1e-87	46.3
WP_074166919.1\|614265_614553_-	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.4e-13	43.7
WP_063417242.1\|614670_614886_-	hypothetical protein	NA	NA	NA	NA
WP_084833013.1\|615231_615513_-	hypothetical protein	NA	NA	NA	NA
WP_131828978.1\|615672_615960_-	hypothetical protein	NA	NA	NA	NA
WP_084833015.1\|615956_616784_-	chromosome partitioning protein ParB	K7PKM7	Enterobacterial_phage	1.1e-95	67.0
WP_084833016.1\|617097_617658_-	siphovirus Gp157 family protein	A0A2I7RAE0	Vibrio_phage	1.5e-11	33.6
WP_084833017.1\|617654_620027_-	hypothetical protein	H9C157	Pectobacterium_phage	6.4e-80	53.3
WP_084833018.1\|620019_620283_-	hypothetical protein	NA	NA	NA	NA
WP_084833019.1\|620363_620711_-	hypothetical protein	NA	NA	NA	NA
WP_084833020.1\|621119_621266_-	hypothetical protein	NA	NA	NA	NA
WP_084833021.1\|621269_622232_-	hypothetical protein	NA	NA	NA	NA
WP_088728377.1\|622404_622812_-	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	1.6e-31	53.7
WP_084833023.1\|622894_623128_+	transcriptional regulator	H9C161	Pectobacterium_phage	9.6e-05	34.0
WP_084833024.1\|623105_623552_+	hypothetical protein	NA	NA	NA	NA
WP_084833025.1\|623592_624402_+	hypothetical protein	A0A1W6JP36	Morganella_phage	3.8e-24	53.3
WP_084833026.1\|624404_625130_+	ATP-binding protein	S4TNF5	Salmonella_phage	1.8e-70	58.5
WP_088728489.1\|625223_626171_+	GCN5 family acetyltransferase	NA	NA	NA	NA
WP_084833027.1\|626167_627073_+	hypothetical protein	NA	NA	NA	NA
WP_084833028.1\|627548_627740_+	hypothetical protein	NA	NA	NA	NA
WP_084833029.1\|627811_628408_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	2.0e-54	55.3
WP_084833030.1\|628404_628701_+	hypothetical protein	A0A2H4FS95	Methylophilaceae_phage	1.1e-24	53.7
WP_088728378.1\|628697_629354_+	antitermination protein	A0A1W6JP37	Morganella_phage	1.2e-20	32.4
WP_084833032.1\|629437_630538_+	ATP-binding protein	NA	NA	NA	NA
WP_084833033.1\|630539_631277_+	DUF4435 domain-containing protein	NA	NA	NA	NA
WP_084833034.1\|632059_632869_+	hypothetical protein	NA	NA	NA	NA
WP_165690318.1\|632932_633277_+	hypothetical protein	NA	NA	NA	NA
WP_084833036.1\|633263_633812_+	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	6.2e-71	71.3
WP_084833037.1\|633953_634415_+	hypothetical protein	NA	NA	NA	NA
WP_165690319.1\|634534_634699_-	hypothetical protein	NA	NA	NA	NA
WP_084833038.1\|634897_635683_+	ParB N-terminal domain-containing protein	R4TG31	Halovirus	5.3e-47	40.7
WP_084833039.1\|635675_636542_+	hypothetical protein	A0A1B1INP7	uncultured_Mediterranean_phage	8.9e-80	53.5
WP_084833040.1\|636538_636796_+	hypothetical protein	NA	NA	NA	NA
WP_165690320.1\|637156_638173_+\|terminase	terminase small subunit	A0A0U2RXW9	Escherichia_phage	1.7e-53	45.9
WP_063417857.1\|638141_639467_+\|terminase	terminase	A0A0N7IRE3	Acinetobacter_phage	8.0e-181	71.1
WP_063417858.1\|639466_640855_+	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	4.0e-130	52.6
WP_063417859.1\|640856_641969_+	hypothetical protein	I6PD76	Cronobacter_phage	7.3e-119	57.3
WP_063417860.1\|642034_642808_+	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	4.7e-64	56.2
WP_063417861.1\|642820_643792_+	Ig domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	4.3e-131	72.4
WP_088728490.1\|643701_644070_+	hypothetical protein	NA	NA	NA	NA
WP_063417862.1\|644109_644592_+	hypothetical protein	A0A2H5BHE7	Acinetobacter_phage	6.2e-22	45.1
WP_063417863.1\|644591_644942_+	hypothetical protein	I6PD77	Cronobacter_phage	6.4e-29	51.7
WP_063417864.1\|644943_645525_+	hypothetical protein	G8C7Q1	Escherichia_phage	1.3e-50	54.2
WP_063417865.1\|645527_645758_+	hypothetical protein	NA	NA	NA	NA
WP_063417888.1\|645760_646171_+	hypothetical protein	A0A2H4J130	uncultured_Caudovirales_phage	2.4e-14	33.8
WP_063417866.1\|646214_647153_+	hypothetical protein	I6PBN6	Cronobacter_phage	2.3e-65	47.9
WP_063417867.1\|647201_647513_+	hypothetical protein	I6PDG2	Cronobacter_phage	2.7e-31	63.1
WP_063417868.1\|647560_647824_+	hypothetical protein	I6PD79	Cronobacter_phage	1.1e-22	67.6
WP_063417869.1\|647823_650610_+\|tail	phage tail tape measure protein	E4WL33	Enterobacteria_phage	1.8e-129	37.6
WP_084832855.1\|650686_651298_+	outer membrane beta-barrel protein	A0A1B0VBR9	Salmonella_phage	3.2e-23	38.0
WP_063417870.1\|651354_651693_+\|tail	phage tail protein	E4WL34	Enterobacteria_phage	7.1e-33	57.1
WP_063417871.1\|651746_652484_+\|tail	phage minor tail protein L	M9NYX1	Enterobacteria_phage	4.4e-120	77.6
WP_063417872.1\|652485_653220_+	peptidase P60	M9NZD8	Enterobacteria_phage	4.2e-107	73.5
WP_063417873.1\|653197_653821_+\|tail	tail assembly protein	K7PH59	Enterobacterial_phage	6.6e-77	71.0
WP_088728491.1\|653893_657406_+	DUF1983 domain-containing protein	E4WL39	Enterobacteria_phage	0.0e+00	64.4
WP_063417875.1\|658925_659327_+	hypothetical protein	A0A1B0V844	Salmonella_phage	1.1e-13	55.7
WP_063417877.1\|660036_660276_+	hypothetical protein	I6PD82	Cronobacter_phage	1.0e-25	67.1
WP_063417878.1\|660277_660655_+	hypothetical protein	Q6UAV9	Klebsiella_phage	1.9e-34	55.6
661849:661876	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1353695 : 1363772

Klosneuvirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063418263.1\|1353695_1355729_-	peptidyl-dipeptidase Dcp	A0A1V0SIU1	Klosneuvirus	1.9e-19	22.6
WP_023292548.1\|1355871_1356618_+	bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG	NA	NA	NA	NA
WP_008502405.1\|1356709_1357396_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_063418264.1\|1357431_1357863_-	universal stress protein	A0A1W6JNV4	Morganella_phage	1.8e-17	34.5
WP_014883679.1\|1358150_1358354_+	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	3.4e-14	58.2
WP_063418265.1\|1358397_1359861_-	mannitol dehydrogenase family protein	H8ZJP8	Ostreococcus_tauri_virus	2.3e-43	29.1
WP_063418266.1\|1360082_1361450_-	MHS family MFS transporter	NA	NA	NA	NA
WP_084833075.1\|1361523_1362543_-	Zn-dependent oxidoreductase	E3SJ82	Synechococcus_phage	3.7e-16	26.9
WP_023292552.1\|1362557_1363772_-	D-galactonate dehydratase family protein	Q6A202	Oenococcus_phage	8.2e-47	29.4

DBSCAN-SWA_5

1863591 : 1961062

103

Enterobacteria_phage(27.78%)

terminase,protease,capsid,holin,portal,integrase,tRNA,head,tail

attL 1861465:1861482|attR 1960871:1960888

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1861465:1861482	attL	NA	NA	NA	NA
WP_023335168.1\|1863591_1864251_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	1.7e-46	53.9
WP_008499906.1\|1864307_1864784_-	hypothetical protein	NA	NA	NA	NA
WP_063418638.1\|1864780_1865533_-	transcriptional regulator	NA	NA	NA	NA
WP_023292856.1\|1865841_1866585_+	hypothetical protein	NA	NA	NA	NA
WP_021240847.1\|1866660_1867167_+	fimbrial protein	NA	NA	NA	NA
WP_063418692.1\|1867239_1869957_+	fimbrial protein	NA	NA	NA	NA
WP_063418691.1\|1869958_1871116_+\|tail	phage tail protein	NA	NA	NA	NA
WP_008499912.1\|1871126_1871678_+	response regulator transcription factor	NA	NA	NA	NA
WP_008499913.1\|1871746_1872076_+	sulfurtransferase TusE	NA	NA	NA	NA
WP_023617863.1\|1872072_1872354_-	acylphosphatase	NA	NA	NA	NA
WP_021240851.1\|1872365_1873154_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_021240852.1\|1873164_1873722_-	kinase inhibitor	NA	NA	NA	NA
WP_063418690.1\|1873895_1875086_+	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_008499919.1\|1875146_1875464_+	heat shock protein HspQ	NA	NA	NA	NA
WP_008499920.1\|1875502_1875916_-	CoA-binding protein	NA	NA	NA	NA
WP_008499921.1\|1876089_1876752_+	DUF2057 family protein	NA	NA	NA	NA
WP_008499922.1\|1876832_1877291_+	methylglyoxal synthase	NA	NA	NA	NA
WP_021240854.1\|1877350_1879405_-	DNA helicase IV	A7KV33	Bacillus_phage	1.8e-17	27.9
WP_008499924.1\|1879528_1879975_+	YccF domain-containing protein	NA	NA	NA	NA
WP_063418689.1\|1879994_1882157_+	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_008499926.1\|1882113_1882740_-	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_023618859.1\|1882957_1883467_+	cell division inhibitor SulA	NA	NA	NA	NA
WP_008499928.1\|1883821_1884877_+	porin OmpA	NA	NA	NA	NA
WP_008499929.1\|1884941_1885394_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_063418688.1\|1885580_1887341_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_008499931.1\|1887409_1887928_+	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA	NA	NA	NA	NA
WP_013097261.1\|1887998_1888166_-	ribosome modulation factor	NA	NA	NA	NA
WP_008499932.1\|1888421_1888988_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_008499933.1\|1888984_1890625_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_008499934.1\|1890629_1891883_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_008499935.1\|1891896_1893804_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	5.6e-50	28.3
WP_021240859.1\|1893816_1895925_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_063418687.1\|1896023_1897133_+	MOSC domain-containing protein	V5UTY8	Synechococcus_phage	9.2e-05	36.2
WP_021240861.1\|1897129_1897672_-	cell division protein ZapC	NA	NA	NA	NA
WP_008499939.1\|1897838_1898849_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_045352017.1\|1899097_1899673_+	NADPH-dependent FMN reductase	NA	NA	NA	NA
WP_025912948.1\|1899665_1900628_+	sulfonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023327036.1\|1900624_1901770_+	FMNH2-dependent alkanesulfonate monooxygenase	NA	NA	NA	NA
WP_063418686.1\|1901779_1902571_+	aliphatic sulfonate ABC transporter permease SsuC	NA	NA	NA	NA
WP_063418685.1\|1902567_1903338_+	aliphatic sulfonates ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-29	38.5
WP_032651183.1\|1903388_1906001_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	9.1e-19	22.0
WP_088728498.1\|1906425_1906692_+	DinI family protein	K7PKM2	Enterobacterial_phage	1.5e-38	94.3
WP_084833089.1\|1906790_1907213_-\|tail	tail fiber assembly protein	B6SCW7	Bacteriophage	4.4e-24	43.1
WP_131828984.1\|1908260_1908629_+	hypothetical protein	NA	NA	NA	NA
WP_084833090.1\|1908593_1909235_-	hypothetical protein	G8C7R6	Escherichia_phage	3.4e-108	86.9
WP_088728499.1\|1909234_1909528_-	hypothetical protein	G8C7R5	Escherichia_phage	1.2e-36	73.2
WP_088728405.1\|1909527_1912701_-	host specificity protein J	O64335	Escherichia_phage	0.0e+00	87.6
WP_000005717.1\|1912754_1913354_-\|tail	tail assembly protein	K7PM97	Enterobacterial_phage	1.1e-79	78.4
WP_024250700.1\|1913408_1913747_-	hypothetical protein	Q6UAW3	Klebsiella_phage	4.0e-20	46.8
WP_088728406.1\|1913770_1914481_-	peptidase P60	K7PJX1	Enterobacterial_phage	4.6e-143	97.4
WP_047352799.1\|1914482_1915241_-\|tail	phage minor tail protein L	K7P6W4	Enterobacteria_phage	5.1e-148	99.6
WP_000963855.1\|1915237_1915576_-\|tail	phage tail protein	K7P7R1	Enterobacteria_phage	6.6e-63	100.0
WP_088728407.1\|1915578_1919082_-\|tail	phage tail tape measure protein	K7P7L6	Enterobacteria_phage	0.0e+00	70.8
WP_032665364.1\|1919128_1919464_-	membrane protein	S4TR42	Salmonella_phage	4.0e-52	93.7
WP_006809154.1\|1919519_1919798_-	DUF4035 domain-containing protein	Q9MCS5	Enterobacteria_phage	1.2e-43	97.8
WP_001549114.1\|1919806_1920190_-\|tail	phage tail protein	K7PKV6	Enterobacterial_phage	4.4e-63	93.7
WP_006809155.1\|1920198_1920642_-	hypothetical protein	K7PHL2	Enterobacterial_phage	4.6e-72	93.8
WP_088728408.1\|1920701_1921049_-	DUF3168 domain-containing protein	Q9MCS8	Enterobacteria_phage	2.5e-57	98.3
WP_088728409.1\|1921045_1921495_-	HK97 gp10 family phage protein	K7P6X4	Enterobacteria_phage	8.4e-74	98.7
WP_045286830.1\|1921491_1921830_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	8.6e-39	71.4
WP_045286829.1\|1921839_1922166_-\|head,tail	phage gp6-like head-tail connector protein	K7PKT4	Enterobacteria_phage	4.9e-55	96.3
WP_053528466.1\|1922165_1922390_-	hypothetical protein	K7PHI6	Enterobacteria_phage	7.5e-15	84.8
WP_063846376.1\|1922429_1923641_-\|capsid	phage major capsid protein	K7PM57	Enterobacteria_phage	9.9e-194	87.2
WP_059509697.1\|1923650_1924499_-\|protease	Clp protease ClpP	K7PH05	Enterobacteria_phage	8.3e-139	92.1
WP_088728410.1\|1924512_1925817_-\|portal	phage portal protein	K7PJU5	Enterobacteria_phage	6.8e-233	93.3
WP_042889604.1\|1925816_1927553_-\|terminase	terminase large subunit	K7PKT2	Enterobacteria_phage	0.0e+00	99.5
WP_045326830.1\|1927552_1928050_-\|terminase	phage terminase small subunit P27 family	K7PHI2	Enterobacteria_phage	5.5e-74	84.8
WP_088728411.1\|1928207_1928558_-	HNH endonuclease	K7PHK9	Enterobacteria_phage	6.0e-51	81.0
WP_088728412.1\|1928557_1929148_-	hypothetical protein	S4TR53	Salmonella_phage	9.0e-100	87.7
WP_087855492.1\|1929129_1930587_-	glycosyltransferase	K7PKP3	Enterobacterial_phage	2.7e-262	87.4
WP_087855493.1\|1930713_1931010_-	hypothetical protein	NA	NA	NA	NA
WP_087855494.1\|1931133_1931328_-	hypothetical protein	K7PM01	Enterobacterial_phage	2.8e-18	91.1
WP_087855495.1\|1931278_1931554_-	hypothetical protein	G8C7W1	Escherichia_phage	5.6e-28	76.7
WP_032665922.1\|1931550_1932093_-	glycoside hydrolase family 108 protein	A0A0U2I1S0	Escherichia_phage	6.2e-79	74.3
WP_023150207.1\|1932092_1932371_-\|holin	phage holin family protein	G8C7V9	Escherichia_phage	4.7e-43	97.8
WP_023150206.1\|1932360_1932750_-	hypothetical protein	G8C7V8	Escherichia_phage	8.9e-64	99.2
WP_023150205.1\|1933529_1934015_-	HNH endonuclease	A0A2I7RSG2	Vibrio_phage	6.0e-25	43.2
WP_088728413.1\|1934309_1935092_-	antitermination protein	F1C595	Cronobacter_phage	5.5e-113	79.1
WP_032648754.1\|1935088_1935400_-	hypothetical protein	NA	NA	NA	NA
WP_000186531.1\|1935401_1937273_-	AAA family ATPase	K7PK08	Enterobacteria_phage	4.5e-230	61.3
WP_088728414.1\|1937376_1938399_-	hypothetical protein	V5URT9	Shigella_phage	4.0e-47	55.6
WP_023306765.1\|1938391_1938601_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_024176468.1\|1938602_1938827_-	helix-turn-helix domain-containing protein	G8C7U2	Escherichia_phage	1.3e-19	59.7
WP_023150198.1\|1938939_1939638_+	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	3.0e-78	62.5
WP_088728415.1\|1939839_1940271_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_032667385.1\|1940337_1940724_+	S24 family peptidase	F1C5A0	Cronobacter_phage	1.5e-39	61.6
WP_006811079.1\|1940830_1941055_+	hypothetical protein	NA	NA	NA	NA
WP_023296234.1\|1941047_1941455_+	hypothetical protein	A0A286S1Q6	Klebsiella_phage	2.1e-47	87.5
WP_165769317.1\|1941426_1942020_+	HNH endonuclease	A0A2I7S010	Vibrio_phage	1.7e-37	47.0
WP_023294928.1\|1942009_1942423_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	6.2e-47	67.2
WP_088728418.1\|1942644_1942791_+	hypothetical protein	A0A1B5FPC2	Escherichia_phage	2.1e-18	79.2
WP_044901828.1\|1942798_1943047_+	excisionase family protein	S4TND0	Salmonella_phage	2.0e-37	90.1
WP_057059451.1\|1943091_1944384_+\|integrase	site-specific integrase	S4TSP2	Salmonella_phage	2.1e-242	95.3
WP_045372998.1\|1944568_1945771_+	nicotinate phosphoribosyltransferase	A0A2L0UZQ6	Agrobacterium_phage	1.3e-44	31.9
WP_021240867.1\|1945937_1947338_+\|tRNA	asparagine--tRNA ligase	A0A2K9V902	Bandra_megavirus	4.2e-79	35.7
WP_008499949.1\|1949185_1950376_+	aspartate transaminase	NA	NA	NA	NA
WP_008499950.1\|1950424_1951072_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_084831940.1\|1951092_1951653_-	YcbK family protein	NA	NA	NA	NA
WP_063418683.1\|1951818_1953642_-	L,D-transpeptidase	NA	NA	NA	NA
WP_063418682.1\|1953820_1958272_-	chromosome partition protein MukB	NA	NA	NA	NA
WP_021240871.1\|1958271_1958976_-	chromosome partition protein MukE	NA	NA	NA	NA
WP_063418681.1\|1958956_1960279_-	chromosome partition protein MukF	NA	NA	NA	NA
WP_008499956.1\|1960282_1961062_-\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
1960871:1960888	attR	NA	NA	NA	NA

DBSCAN-SWA_6

4687892 : 4732655

Salmonella_phage(88.37%)

terminase,lysis,capsid,portal,integrase,tRNA,head,tail,plate

attL 4689282:4689328|attR 4721524:4721570

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_084832983.1\|4687892_4689089_-\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	3.6e-103	49.9
4689282:4689328	attL	NA	NA	NA	NA
WP_088544957.1\|4689445_4690471_-\|integrase	site-specific integrase	A0A1S6L016	Salmonella_phage	1.2e-195	95.3
WP_033146282.1\|4690474_4691107_-	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	9.1e-66	58.6
WP_033146281.1\|4691223_4691472_+	hypothetical protein	A0A1S6KZZ6	Salmonella_phage	6.8e-25	70.7
WP_033146280.1\|4691504_4692014_+	phage regulatory CII family protein	A0A1S6L008	Salmonella_phage	2.3e-83	92.3
WP_032442472.1\|4692021_4692222_+	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	6.7e-31	92.4
WP_048971665.1\|4692185_4692527_+	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	9.0e-52	87.6
WP_001744223.1\|4692594_4692828_+	DUF2732 domain-containing protein	E5G6L6	Salmonella_phage	5.4e-24	80.5
WP_088728464.1\|4692827_4693055_+	TraR/DksA family transcriptional regulator	A0A1S6L007	Salmonella_phage	3.1e-32	88.0
WP_024552872.1\|4693051_4693912_+	DNA adenine methylase	E5G6L8	Salmonella_phage	2.2e-131	81.1
WP_088728465.1\|4693902_4696311_+	replication endonuclease	A0A1S6L028	Salmonella_phage	0.0e+00	96.9
WP_001154443.1\|4696472_4696661_+	hypothetical protein	A0A1S6L006	Salmonella_phage	6.1e-26	98.4
WP_001217561.1\|4696672_4696906_+	DinI family protein	A0A1S6L014	Salmonella_phage	2.2e-33	92.2
WP_088728466.1\|4697267_4698077_+	TIGR04255 family protein	NA	NA	NA	NA
WP_024552869.1\|4698096_4698759_+	hypothetical protein	NA	NA	NA	NA
WP_013098799.1\|4698768_4699617_+	hypothetical protein	NA	NA	NA	NA
WP_007866320.1\|4699654_4700692_-\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	1.1e-177	88.1
WP_063812752.1\|4700691_4702458_-\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	94.9
WP_088728467.1\|4702600_4703434_+\|capsid	GPO family capsid scaffolding protein	E5G6M5	Salmonella_phage	3.8e-128	97.5
WP_023223453.1\|4703450_4704512_+\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	2.3e-194	98.9
WP_024552863.1\|4704515_4705166_+	hypothetical protein	A0A1S6KZX1	Salmonella_phage	1.4e-114	99.5
WP_088728468.1\|4705259_4705724_+\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	1.0e-82	96.1
WP_000868193.1\|4705723_4705927_+\|tail	tail protein X	E5G6M9	Salmonella_phage	1.9e-33	98.5
WP_000171565.1\|4705930_4706146_+	hypothetical protein	E5G6N0	Salmonella_phage	5.9e-33	100.0
WP_088728469.1\|4706126_4706636_+	lysozyme	A0A1S6KZY9	Salmonella_phage	4.1e-93	98.2
WP_088728470.1\|4706640_4707018_+	peptidase	A0A1S6KZZ2	Salmonella_phage	1.5e-60	97.6
WP_165769320.1\|4707014_4707443_+\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	2.1e-66	97.2
WP_001039961.1\|4707538_4707970_+\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	1.1e-75	99.3
WP_088728472.1\|4707962_4708409_+	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	8.4e-66	89.0
WP_088728473.1\|4708477_4709056_+\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	4.8e-106	96.9
WP_023306992.1\|4709052_4709412_+\|plate	phage baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	8.3e-56	93.3
WP_088728474.1\|4709398_4710307_+\|plate	baseplate assembly protein	A0A1S6KZY6	Salmonella_phage	1.7e-145	92.1
WP_088728475.1\|4710299_4710905_+\|tail	phage tail protein I	E5G6N9	Salmonella_phage	3.3e-113	96.0
WP_088728476.1\|4710901_4712374_+\|tail	phage tail protein	A0A1S6KZZ8	Salmonella_phage	4.5e-116	64.2
WP_088728507.1\|4712298_4712802_+\|tail	tail fiber assembly protein	U5P0S4	Shigella_phage	6.0e-20	69.6
WP_088728477.1\|4712773_4713181_-\|tail	phage tail protein	U5P083	Shigella_phage	1.7e-20	47.8
WP_088728478.1\|4713542_4714100_+	recombinase family protein	A0A1S6L009	Salmonella_phage	8.8e-81	83.1
WP_088728479.1\|4714204_4715377_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	2.3e-211	93.8
WP_024552851.1\|4715386_4715902_+\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	5.1e-91	98.2
WP_073511638.1\|4715956_4716259_+\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	3.0e-43	96.0
WP_023206368.1\|4716273_4716393_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	5.7e-14	92.3
WP_088728480.1\|4716385_4719544_+\|tail	phage tail tape measure protein	A0A1S6L010	Salmonella_phage	0.0e+00	68.8
WP_013098780.1\|4719540_4720026_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	1.7e-72	94.4
WP_088728481.1\|4720022_4721123_+	phage late control D family protein	E5G6Q3	Salmonella_phage	4.5e-185	91.8
WP_045334934.1\|4721191_4721410_+	levansucrase regulator	Q53ZE7	Salmonella_virus	5.7e-36	94.4
WP_008502505.1\|4721978_4722461_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.3e-29	47.4
4721524:4721570	attR	NA	NA	NA	NA
WP_023325904.1\|4722578_4723055_+	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_008502503.1\|4723044_4723332_+	RnfH family protein	NA	NA	NA	NA
WP_008502502.1\|4723440_4723779_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_044597776.1\|4723917_4725579_-	DNA repair protein RecN	NA	NA	NA	NA
WP_008502500.1\|4725664_4726543_-	NAD(+) kinase	NA	NA	NA	NA
WP_063418433.1\|4726665_4727259_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_063418434.1\|4727311_4728598_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_008502497.1\|4728616_4729483_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_008502496.1\|4729574_4730936_+	signal recognition particle protein	NA	NA	NA	NA
WP_003863133.1\|4731052_4731301_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_021241995.1\|4731316_4731856_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_008502493.1\|4731887_4732655_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP022149

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022149_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022149_1

50290-50424

Orphan

Consensus_repeat	Method
TGGAATATCGATTCCACACGCCGGATTTAACTGGGACCACGGTCCCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022149_1

>merge|NZ_CP022149|1|50290-50424|CRISPRCasFinder
TGGAATATCGATTCCACACGCCGGATTTAACTGGGACCACGGTCCCACCTCCTACTTGCGTGTCAGAACTCATCCTTCAACCCCGCCTGGAATATCGATTCCACACGCCGGATTTAACTGGGACCATGGTCCCAC

>NZ_CP022149|1|1|50290-50424|CRISPRCasFinder
TGGAATATCGATTCCACACGCCGGATTTAACTGGGACCACGGTCCCAC	CTCCTACTTGCGTGTCAGAACTCATCCTTCAACCCCGCC
TGGAATATCGATTCCACACGCCGGATTTAACTGGGACCATGGTCCCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022149.1\|WP_084832861.1\|59295_59964_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NZ_CP022149.1\|WP_084833189.1\|61954_62269_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022149.1\|WP_039025123.1\|60931_61090_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|182055
NZ_CP022149.1\|WP_045286915.1\|51897_54036_+\|ATPase-AAA	unknown	unknown	gnl\|CDD\|213202
NZ_CP022149.1\|WP_013087134.1\|48985_49951_+\|ParB/RepB/Spo0J-family-plasmid-partition-protein	unknown	unknown	gnl\|CDD\|184254
NZ_CP022149.1\|WP_039025472.1\|46068_47079_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP022149.1\|WP_058842236.1\|40385_43067_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|213207
NZ_CP022149.1\|WP_045286910.1\|57185_59312_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271187
NZ_CP022149.1\|WP_039025473.1\|47819_48986_+\|plasmid-partitioning-protein-SopA	unknown	unknown	gnl\|CDD\|184261
NZ_CP022149.1\|WP_045324946.1\|38106_38445_+\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|226074
NZ_CP022149.1\|WP_013087126.1\|43619_43910_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022149.1\|WP_084833191.1\|63118_63910_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|280533
NZ_CP022149.1\|WP_045332705.1\|62877_63078_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022149.1\|WP_084833190.1\|62328_62790_+\|DUF1419-domain-containing-protein	unknown	unknown	gnl\|CDD\|369265
NZ_CP022149.1\|WP_013087127.1\|44040_44571_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022149.1\|WP_072268114.1\|54385_55789_+\|DNA-cytosine-methyltransferase	unknown	unknown	gnl\|CDD\|236696
NZ_CP022149.1\|WP_000790483.1\|37531_37963_+\|silver-binding-protein-SilE	unknown	unknown	unknown
NZ_CP022149.1\|WP_039025471.1\|44589_45366_+\|phage-integrase-family-protein	unknown	unknown	gnl\|CDD\|334163
NZ_CP022149.1\|WP_164722686.1\|55822_57037_-\|type-II-site-specific-deoxyribonuclease	unknown	unknown	gnl\|CDD\|370247
NZ_CP022149.1\|WP_063157427.1\|38922_39831_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|225724

Protein	Function_ID	Function_description	E-value
NZ_CP022149.1\|WP_084832861.1\|59295_59964_-\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	3.76586e-28
NZ_CP022149.1\|WP_063157427.1\|38922_39831_-\|HNH-endonuclease	gnl\|CDD\|225724	COG3183, COG3183, Predicted restriction endonuclease [Defense mechanisms].	6.31339e-09
NZ_CP022149.1\|WP_045286915.1\|51897_54036_+\|ATPase-AAA	gnl\|CDD\|213202	cd03235, ABC_Metallic_Cations, ATP-binding cassette domain of the metal-type transporters. This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.	1.30885e-05
NZ_CP022149.1\|WP_013087134.1\|48985_49951_+\|ParB/RepB/Spo0J-family-plasmid-partition-protein	gnl\|CDD\|184254	PRK13698, PRK13698, ParB/RepB/Spo0J family plasmid partition protein.	0
NZ_CP022149.1\|WP_039025472.1\|46068_47079_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	0.000178458
NZ_CP022149.1\|WP_058842236.1\|40385_43067_-\|AAA-family-ATPase	gnl\|CDD\|213207	cd03240, ABC_Rad50, ATP-binding cassette domain of Rad50. The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.	0.00022638
NZ_CP022149.1\|WP_039025473.1\|47819_48986_+\|plasmid-partitioning-protein-SopA	gnl\|CDD\|184261	PRK13705, PRK13705, plasmid-partitioning protein SopA; Provisional.	0
NZ_CP022149.1\|WP_045324946.1\|38106_38445_+\|DUF305-domain-containing-protein	gnl\|CDD\|226074	COG3544, COG3544, Uncharacterized protein conserved in bacteria [Function unknown].	2.37889e-23
NZ_CP022149.1\|WP_084833191.1\|63118_63910_+\|N-6-DNA-methylase	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	2.06487e-10
NZ_CP022149.1\|WP_084833190.1\|62328_62790_+\|DUF1419-domain-containing-protein	gnl\|CDD\|369265	pfam07215, DUF1419, Protein of unknown function (DUF1419). This family consists of several bacterial proteins of around 110 residues in length. Members of this family seem to be specific to Agrobacterium species and to Rhizobium loti. The function of this family is unknown.	0.00107459
NZ_CP022149.1\|WP_039025123.1\|60931_61090_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|182055	PRK09738, PRK09738, small toxic polypeptide; Provisional.	7.30258e-24
NZ_CP022149.1\|WP_072268114.1\|54385_55789_+\|DNA-cytosine-methyltransferase	gnl\|CDD\|236696	PRK10458, PRK10458, DNA cytosine methylase; Provisional.	0
NZ_CP022149.1\|WP_164722686.1\|55822_57037_-\|type-II-site-specific-deoxyribonuclease	gnl\|CDD\|370247	pfam09019, EcoRII-C, EcoRII C terminal. The C-terminal catalytic domain of the Restriction Endonuclease EcoRII has a restriction endonuclease-like fold with a central five-stranded mixed beta-sheet surrounded on both sides by alpha-helices. It cleaves DNA specifically at single 5' CCWGG sites.	6.70144e-90
NZ_CP022149.1\|WP_039025471.1\|44589_45366_+\|phage-integrase-family-protein	gnl\|CDD\|334163	pfam00589, Phage_integrase, Phage integrase family. Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase are Arg-173, His-289, Arg-292 and Tyr-324.	8.99879e-39
NZ_CP022149.1\|WP_045286910.1\|57185_59312_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271187	cd01187, INT_tnpB_C_Tn554, Putative Transposase B from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase B from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.04935e-15

>NZ_CP022149.1|WP_013087134.1|48985_49951_+|ParB/RepB/Spo0J-family-plasmid-partition-protein
MKRAPVIPKHTVKDIRPETEPSAAPAAPMVDSLIARVGAMARGNTILLPVCGREVKFILEAIPGESVETASRVWSGNERDQELLTEDALDDLIPSFMLSGQQTPAFGRRVEGVIEIADGSRRRKAAILTSSDYRVLVGDLDDEQMMALSRLGNDYRPVSAYERGNRYAQRLENDFNGNISALAEAENISRKIITRCINTAHLPKSVVALFTHPGELSARSGETLYKAFSGKEALLLQRTQQLHEQKKAGVIFESEEVIGLLTDVLKEPSGKKVNLNTRHQFVPGATALYKGDKVIFNLDKSRLPAECIEKIESILRDLQKV
>NZ_CP022149.1|WP_039025473.1|47819_48986_+|plasmid-partitioning-protein-SopA
MGLMETLDQCITAGHEMTKAIAIAQFNDDSPEARKITRRWRVGEAADLIGVSSQAIRDAEKAGRLPHPDMEMRGRVEQRVGYTIEQINLMRDVFGTRLRRPDDSVPPVIAVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDLHIHAEDTLLPFYLGERDDAAYAVKATCWPGLDIIPSCLALHRIETELMGRFDNGKLPTEPHMMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDMLRDLLKNVDLQGFEPDVRILLTKYSNNNGSQSPWMEEQIRDAWGSMVLKNVVRETDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR
>NZ_CP022149.1|WP_039025472.1|46068_47079_-|replication-initiation-protein
MAMENNELPLNLQEVNKTTGEVVKLDVNSASTVQPVALMRLGLFVPTLKSTSRSKTNRKNVTDATEELVQLSIARSEGYTDVRITGSRLDMDTDFKVWLGIIRSMYDFGVKDDTLKLSFVEFVKMCGFDSRRSNKKMRDRISNSLFKLASVTLKFQSETKGWTTHLVQSAYYDITADVVEIRAEPNLFELYQMDRRVLLRLKAIDALQRKESAQALYTYIESLPQNPAPISMKRMRDRLNLTSNLYTQNHTVRKAMAQLKDIGYLDYTEFKRGRATYFSVHYRNPKLISSKVVVPREPEEEVPEQNYDEVIKALKAAGIDPQKLAKALASVKPGND
>NZ_CP022149.1|WP_039025471.1|44589_45366_+|phage-integrase-family-protein
MMPALPGHSGAFSSAQLPVVIDYPAALALRQMALVQDELPKYLLAPEVSALLHYVPDLHRKMLLTTLWNTGARINEALALTRSDFSLAPPYPFVQLATLKQRVEKAARTAGRAPAGSQPHRNVPLSDPQYARQLEMMVATLKIPLERRNKRTGRTEKVRIWEITDRTVRTWLGEAVEAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFSMAEADAVAMLKKR
>NZ_CP022149.1|WP_013087127.1|44040_44571_+|hypothetical-protein
MCKLTGFIMGLTILLGVTARDAGAATLSEMRMVNASQKPGMVIICSRTSEIPQKGESPVRIESLLRGVVLQNDGDRMMFDVTYTQRNAEESIPFRTEKYRLTTELEATRQKMAIDPETIELSLPRARGLEETFLAGMKASPVSFEDYTNYRVKSATEYLILPGPASPDAPVMHCTL
>NZ_CP022149.1|WP_013087126.1|43619_43910_+|hypothetical-protein
MNMKITLSVLFEALIILGHDRVWMEESEFEHIYGYGCYREIHTWDDRTVAWWDDADDTWYLSTEVDVITPFLGPLPKKEGELSEEKCFQLMTLGRY
>NZ_CP022149.1|WP_058842236.1|40385_43067_-|AAA-family-ATPase
MKGSEWNKWDLHIHSPVTWQANGYAGQCDIARYVQLLGEKQLSLIAVTNYFYFRQNELEIIREEIARQNLNITVLGNVEFRLDQQNKAGDFINVHILFSDRISTERINEALSRFPLRLTDGDRKAIYCCEKSVADSGHGVDTIVVAFSALLEHLSASFRPFRDYLVAVCPNGYGGYRPDANGRSAAIATEIDRQGQMIFGGKGDREFFLRTDRYDGASVKPVFLCSDAHRMEDIGGRYTWVKALPTFEGLRQALLEPEARLRIGEEWLAELTPKAHFSQIDVEGTIFDGQEISFRKLSIPLSQDMVAIIGGRGTGKSLLLDALRSRFAGAAARGSDQRDVNVQHMSIELDKANGEKIRFDTRSEGYEYLHVSQGEIKKLCQEPGLISDEIKKMLRLTPTHEAGNTAAQLAENLSAWRAWREFSLFRSAHSEPVNTRHFQLNIIRAAQEKIEVLTSDRNKALIETFRENSRRQTLLLQTRDKLTGVRADIVTAAEDLNARIAAINAEDTAHEAIPLVDLSAQTGVIERRLLSVQEQTEQFGRDNDEIIGAFREQGLGQDITGLLEKVHEYQRQTELAETHLREIGHQETLYRSGLEQRTRLAAEFMDGLLSRQGVIDTAFASLTTKPHLTQDQQALIQDILTDIRIYGQPHFDVTAFYNGMLSCLNRGRFRAAGELTTQDRLREVFRISSIDEFRALLANEPMLVLPECPDNKLTLEAFFWRDEYFNSQGPDALLSYLFSPEQIQRYLNVRAEFEYKGKTVEKLSAGQRGTFYVCLKLATDAFGSPFVFDQPEDDLDNDFIMHSLVPLFRKIKQYRQVIIVTHNANLVVNCDAEQVIIAANNDEVISYRSGALEYGDHGAPNSMRKAICDVLEGGRQAFEAREQKYGMLWLNAI
>NZ_CP022149.1|WP_063157427.1|38922_39831_-|HNH-endonuclease
MIEKICEVIDGEYICDIDISVEEWKILLKNKKVFDEKSIAALKKWFIEPNHSCTCFDIGKKYDLHSMSANGVINGLGGRVQKELGRFEVKGIGNIAAGTKFITVMNSKEIDVKPKRNLWTIREELVQAIKELDFFGETQSTNTEFYSDDELINAIDENSEFEDALKFEYSGIAKPKKNAIEVKNGLLYPRSKAVSKNALNKAGYRCEVDGDHPTFRRRNSTLNYTEPHHIVPMSKQDDFEVSLDVEENIISLCCNCHKKIHLGEGFEGMLEKIYAERKELLKKVDIDITLENLILFYKMEGK
>NZ_CP022149.1|WP_045324946.1|38106_38445_+|DUF305-domain-containing-protein
MKIKNAFFVILMLSLSAISAEHSVMKMSDMSSSSQEYMTSMKDMHEKMMTGVNDSDPDKAFAKGMIAHHEGAIGMAETELKYGKDPEMRKLAQDIIKAQKGEIEKMKKWLNH
>NZ_CP022149.1|WP_000790483.1|37531_37963_+|silver-binding-protein-SilE
MKNIVLASLLGFGLISSAWATETVNIHDRVNNAQAPAHQMQSAAAPVGIQGTAPRMTGMDQHEQAIIAHETMTNGSADAHQKMVESHQKMMGNNTVSTTVPSTSYAAMNEHERAAVAHEFMNNGQSGPHQAMAEAHRRMINAG
>NZ_CP022149.1|WP_045286915.1|51897_54036_+|ATPase-AAA
MDVEINYCNNIDNACITLSENKLNIKFAPNGTGKSTISRAILHSVSRDAAGLNSLLPFKFRAANPDEFQPSVTGTEQIQDVMCFDEKYVSQFTFQPDELISNSFDIFIKTEAYNQTEREIDSMVMAIRQEFSGNDELELFITHLQELSGAFKLTSKGLSKASTGMKGLAGGNKLQHIPSGLEPYQPFIQSPRNVEWIEWQTKGYENFCSLSEGCCPFCTGDSHEKAEQISKVSAEYDKAVIKNLVGIITVLDKLGEYFSEAARSRLREITTLQGGLEKKHEDYLVTVKQQTENLLAMLLTLKTLNSFTFNDAGNIRASLASFRLDVKYFSELQSDKTLATIGRLNASLDSLISQAGLLQGQINKQRAGMQRLIQKHKKDINTFLAYAGYRYQVDISGDGEQCRLKLRHVDYTDYLSGGSQHLSYGERNAFSIVLFMYECLARKPNLIILDDPISSFDKNKKFAILEMLFRRDSSECLKNQTVLMLTHDVEPIIDTLKSVKKLFSNQVTASYLRYSTGTITELPIRESDILTFAQICKVVLESDCDDLIKLIYLRRHYEIMDNRGDVYQVLSNLFHRREEPIDTRLPLIEGTGYPMMDPESFLNGCSLITKNIFGFDYPHMLSLLNDPDKILSLYRSCTNGYEKLQVFRLLEPEADNRVIRKFVNETYHIENEFICQLDPTRFDLIPEYVIVECDRLLLNIEASNDDAELETA
>NZ_CP022149.1|WP_072268114.1|54385_55789_+|DNA-cytosine-methyltransferase
MLEKAEAEEQLRQENDKKLLGQVLEIYDQKYVAELLRKVGKNEWSRETLNRWINGKCSPKSLTLAEEELLRKMLPEAPAHHPDYAFRFIDLFAGIGGIRKGFETIGGQCVFTSEWNKEAVRTYKANWFNDAQEHTFNLDIREVTLSDKPEVPENDAYAYINEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARIIRAKKPAIFVLENVKNLKSHDKGKTFKVIMDTLDELGYEVADAAEMGKNDPKVIDGKHFLPQHRERIVLVGFRRDLNIHQGFTLRDISRFYPEQRPSFGELLEPVVDSKYILTPKLWEYLYNYAKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGETDFANEENQAHRPRRLTPRECARLMGFEKVDGRPFRIPVSDTQSYRQFGNSVVVPVFEAVAKLLEPYILKAVYADSCKVERI
>NZ_CP022149.1|WP_164722686.1|55822_57037_-|type-II-site-specific-deoxyribonuclease
MLMSVFHNWLLEMACENYFVYIKRLSANDTGATGGHQVGLYIPSGIVEKLFPSINHTRELNPSVFLTAHVSSHDCPDSEARAIYYNSRHFGKTRNEKRITRWGRGSPLQDPENTGALTLLAFKLDEQGGDCKEVNIWVCASTDEEDVIETAIGEVIPGALISGPAGQILGGLSLQQAPVNHKYILPEDWHLRFPSGSEIIQYAASHYVKNSLDPDEQLIDRRRVEYDIFLLVEELHVLDIIRKGFGSVDEFIALANSVSNRRKSRAGKSLELHLEHLFIEHGLRHFATQAVTEGNKKPDFLFPSAGAYHDTEFPVENLRMLAVKTTCKDRWRQILNEADKIHQVHLFTLQEGVSLAQYREMRESGVRLVVPSSLHKKYPEAVRAELMTLGAFIAELTGLYADIP
>NZ_CP022149.1|WP_045286910.1|57185_59312_-|tyrosine-type-recombinase/integrase
MTGKRDKGFIYAHFCRADYDLHAGFSSEQKEALSTSHKRSRNYGRSGSLSSLITPLLDIANNSGTGCRLTRTVIMAMLTEMQNVGQPCWNWREDQWISLFDKYRRGKPLMMAFAYHLGPFTSPLQIPHENTLSLYASAIYGNAIFRDQLNRLSEALISLGYSPQHLRHAVSSPLGLLMLLNDNPRLEDMTTELLWQAQQYHDKRVSRHVGKISHGLAALGIIAKPVRMRNYTEWHEKPVENISPEWVAWCRRWRETSVLRPRTRENQYSFILRCGLWLAKEHPEVKVPTDWSIETCASFIAAVGRMKVDELSLGTEHGLRKSKRSGEPMMPHSRAHFIYSLRRFMSDFELWGWGRLNFSPARHLFTPDTPLFRRGVNPRVIDDPVWLKLIWASLNLRHEDLLSEIHYPLSMLQAMAVIWTHAGLRQNELLRLTMECVTPQSEDIIREDGSVVPAGTLCYLNVPAGKTSKAFVKPVSVIVKKYVDIWLNVRPVDQAKLNDDRTGEKVRYLFQYRGKPAGSDVINRTVIPVLCARAGLPVEDSGGAITSHRGRASALTALASVPQGMSLYELMQWSGHSSPQSTLHYIRIRPTQLAASFVKADRIAHMISVLVDHDPEAVSPTGPATYYDLGESFCMNPFWSSCPHRMACIGCDFNLLKDSARGLMLESKTSIRRYLEEVPLTPDEKAIVEQDIKKVEQALAKLTGKSGG
>NZ_CP022149.1|WP_084832861.1|59295_59964_-|site-specific-integrase
MNKLGPLPVQRITRLPQIPDDGQWYHLLGYISDCSLRDRLMLALAYHGALRRSEVTTITIEDIDPAHRLIRIRAENTKGKRERVVCYGPAITPVLAAHLRNLRQTGITGGALFRSFSDRNYGSPLSYWSWSKTVREWSDRTNMPFLTTHTFRHLRLTHLARAGWKLHEIATYAGHRDLRTTQIYIHLSGTDLAARMAMTVAETDRKIAAIMFGQERENDRQA
>NZ_CP022149.1|WP_039025123.1|60931_61090_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MKLPRNTLLWCVLIVCLTLLVFTYLTRKSLCEIRYRDTNREVAAFMAYESAK
>NZ_CP022149.1|WP_084833189.1|61954_62269_+|hypothetical-protein
MHTRNVNVKTAGGESSRKMGGKTVSYTILVAETKKNSDEETDVLEFSSLAELKKLRRSCPETMRCTYFYALSSGVDKQFRHIHVAEADHFKQFVRLIERAGIDI
>NZ_CP022149.1|WP_084833190.1|62328_62790_+|DUF1419-domain-containing-protein
MNVNTPTAAPMAFFVPSHNAVYDRATQLEGQWVTQREAITLESLRRLYPDAELIPATLVQEKQNDGYRRPWVEITEARYIDQMETLPPVDWCRGYGGESFKSMEFTGGDVTAIFVRYGARFFECYDLHTRHHRELIGDVIARFCLDAPLNSAH
>NZ_CP022149.1|WP_045332705.1|62877_63078_+|hypothetical-protein
MNFDPQTVAQAKAFVNALRAGKRARVPALRFSQWQPFLSVVNAETGYAADADCGLAVSVYPALGLA
>NZ_CP022149.1|WP_084833191.1|63118_63910_+|N-6-DNA-methylase
MSQLSFESLFLADQADPQPWASDPVRVQSPAEARKQFASVFRQTAKYMRRSEVFRDFITLAASGLDIASIRSPESIENSRRICGRYQPEDLDAMRQLFCLLVEGLAGEMHDFLGAVYMEHELGADEMGQYFSPSSISRLMAGLLMPGAQETIKREGWMTLDEPACGSAGMVIAFAYWMAEAGYNPSEQLYATCTDIDPMVADMAFIQLSLLGIPAKVVTGNTLTLKANRVRYTPVYYFNDWQGRLEFRSRFEAMKNFLATVAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP035636	Enterobacter cloacae strain EN3600 plasmid unnamed4, complete sequence	100226-100264	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP017182	Enterobacter kobei strain DSM 13645 plasmid pDSMZ13645, complete sequence	1315-1353	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP017182	Enterobacter kobei strain DSM 13645 plasmid pDSMZ13645, complete sequence	1402-1440	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP031569	Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence	7815-7853	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP050011	Citrobacter sp. Y3 plasmid unnamed2, complete sequence	27572-27610	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP019840	Enterobacter roggenkampii strain R11 plasmid pASM1, complete sequence	70340-70378	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP022149	Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_1, complete sequence	50338-50376	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP009855	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-22e, complete sequence	14593-14631	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP008907	Enterobacter hormaechei subsp. hoffmannii ECR091 plasmid pENT-4bd, complete sequence	83191-83229	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP026851	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1	65584-65622	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_LT991956	Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2	52487-52525	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP029719	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence	1341-1379	0	1.0
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP012428	Klebsiella pneumoniae strain KP5 plasmid pSg1-2, complete sequence	20127-20165	1	0.974
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NC_014107	Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_A, complete sequence	48095-48133	1	0.974
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP046273	Enterobacter hormaechei strain E70 plasmid pE70-sul2, complete sequence	40032-40070	1	0.974
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP012169	Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-210.894kb, complete sequence	40032-40070	1	0.974
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP042541	Enterobacter hormaechei strain C4 plasmid pC4_001, complete sequence	40032-40070	1	0.974
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP031723	Enterobacter hormaechei strain WCHEH020038 plasmid p2_020038, complete sequence	50311-50349	1	0.974
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP042567	Enterobacter hormaechei strain C44 plasmid pC44_001, complete sequence	40032-40070	1	0.974
NZ_CP022149_1	1.1\|50338\|39\|NZ_CP022149\|CRISPRCasFinder	50338-50376	39	NZ_CP039454	Enterobacter bugandensis strain 220 plasmid pSurvcare220, complete sequence	72766-72804	2	0.949

1. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP035636 (Enterobacter cloacae strain EN3600 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

2. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP017182 (Enterobacter kobei strain DSM 13645 plasmid pDSMZ13645, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

3. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP017182 (Enterobacter kobei strain DSM 13645 plasmid pDSMZ13645, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

4. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP031569 (Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

5. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP050011 (Citrobacter sp. Y3 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

6. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP019840 (Enterobacter roggenkampii strain R11 plasmid pASM1, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

7. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP022149 (Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_1, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

8. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP009855 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-22e, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

9. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP008907 (Enterobacter hormaechei subsp. hoffmannii ECR091 plasmid pENT-4bd, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

10. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP026851 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

11. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_LT991956 (Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

12. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP029719 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgcc	Protospacer
***************************************

13. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP012428 (Klebsiella pneumoniae strain KP5 plasmid pSg1-2, complete sequence) position: , mismatch: 1, identity: 0.974

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgtc	Protospacer
*************************************.*

14. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NC_014107 (Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_A, complete sequence) position: , mismatch: 1, identity: 0.974

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgtc	Protospacer
*************************************.*

15. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP046273 (Enterobacter hormaechei strain E70 plasmid pE70-sul2, complete sequence) position: , mismatch: 1, identity: 0.974

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgtc	Protospacer
*************************************.*

16. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP012169 (Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-210.894kb, complete sequence) position: , mismatch: 1, identity: 0.974

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgtc	Protospacer
*************************************.*

17. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP042541 (Enterobacter hormaechei strain C4 plasmid pC4_001, complete sequence) position: , mismatch: 1, identity: 0.974

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgtc	Protospacer
*************************************.*

18. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP031723 (Enterobacter hormaechei strain WCHEH020038 plasmid p2_020038, complete sequence) position: , mismatch: 1, identity: 0.974

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgtc	Protospacer
*************************************.*

19. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP042567 (Enterobacter hormaechei strain C44 plasmid pC44_001, complete sequence) position: , mismatch: 1, identity: 0.974

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtgtcagaactcatccttcaaccccgtc	Protospacer
*************************************.*

20. spacer 1.1|50338|39|NZ_CP022149|CRISPRCasFinder matches to NZ_CP039454 (Enterobacter bugandensis strain 220 plasmid pSurvcare220, complete sequence) position: , mismatch: 2, identity: 0.949

ctcctacttgcgtgtcagaactcatccttcaaccccgcc	CRISPR spacer
ctcctacttgcgtttcagaactcatccgtcaaccccgcc	Protospacer
************* ************* ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13303 : 75157

Bacillus_phage(22.22%)

integrase,transposase

attL 72761:72776|attR 80183:80198

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067855.1\|13303_14008_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000427623.1\|14567_15572_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_013087106.1\|15919_16180_+	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_013087107.1\|16166_16463_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_032664823.1\|16681_17116_-	copper resistance system metallochaperone PcoE	NA	NA	NA	NA
WP_032638101.1\|17331_18732_-	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	2.4e-18	26.6
WP_001188930.1\|18728_19409_-	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4
WP_000998778.1\|19463_20393_-	copper resistance inner membrane protein PcoD	NA	NA	NA	NA
WP_000025662.1\|20397_20778_-	copper resistance system metallochaperone PcoC	NA	NA	NA	NA
WP_001242438.1\|20817_21714_-	copper resistance outer membrane transporter PcoB	NA	NA	NA	NA
WP_001023257.1\|23764_24214_+	copper resistance protein	NA	NA	NA	NA
WP_004118669.1\|24502_25240_+	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4JAF5	uncultured_Caudovirales_phage	1.2e-11	32.5
WP_000843497.1\|25273_25471_-	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_004098955.1\|25511_27959_-	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	7.6e-84	35.8
WP_000758228.1\|28085_28526_-	hypothetical protein	NA	NA	NA	NA
WP_004098958.1\|28612_31759_-	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	S5VTK5	Leptospira_phage	4.0e-61	22.5
WP_004098959.1\|31769_33062_-	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_001246153.1\|33175_33529_-	cation efflux system protein CusF	NA	NA	NA	NA
WP_000475503.1\|33557_34943_-	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_000697969.1\|35132_35813_+	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.1e-31	36.0
WP_000555737.1\|35805_37281_+	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_000790483.1\|37531_37963_+	silver-binding protein SilE	NA	NA	NA	NA
WP_045324946.1\|38106_38445_+	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	1.3e-18	52.0
WP_063157427.1\|38922_39831_-	HNH endonuclease	NA	NA	NA	NA
WP_058842236.1\|40385_43067_-	AAA family ATPase	NA	NA	NA	NA
WP_013087126.1\|43619_43910_+	hypothetical protein	NA	NA	NA	NA
WP_013087127.1\|44040_44571_+	hypothetical protein	NA	NA	NA	NA
WP_039025471.1\|44589_45366_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	7.0e-52	91.2
WP_039025472.1\|46068_47079_-	replication initiation protein	J9Q7H0	Salmonella_phage	1.8e-84	54.9
WP_039025473.1\|47819_48986_+	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	1.0e-216	94.1
WP_013087134.1\|48985_49951_+	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	9.8e-136	76.9
WP_045286915.1\|51897_54036_+	ATPase AAA	NA	NA	NA	NA
WP_072268114.1\|54385_55789_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	9.0e-106	50.6
WP_164722686.1\|55822_57037_-	type II site-specific deoxyribonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.9
WP_045286910.1\|57185_59312_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_084832861.1\|59295_59964_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_039025123.1\|60931_61090_+	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_084833189.1\|61954_62269_+	hypothetical protein	NA	NA	NA	NA
WP_084833190.1\|62328_62790_+	DUF1419 domain-containing protein	NA	NA	NA	NA
WP_045332705.1\|62877_63078_+	hypothetical protein	NA	NA	NA	NA
WP_084833191.1\|63118_63910_+	N-6 DNA methylase	H7BVT3	unidentified_phage	3.9e-13	36.0
WP_084833192.1\|63953_64289_+	hypothetical protein	NA	NA	NA	NA
WP_057068878.1\|64975_65269_+	hypothetical protein	NA	NA	NA	NA
WP_039025116.1\|65285_66107_+	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	6.3e-51	42.5
WP_039025117.1\|66134_66674_-	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_039025118.1\|67247_67643_+	conjugal transfer protein	NA	NA	NA	NA
WP_084833186.1\|67675_68317_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_088728509.1\|70535_72095_+	conjugal transfer protein TraI	NA	NA	NA	NA
WP_013087230.1\|72122_72908_+	DsbA family protein	NA	NA	NA	NA
72761:72776	attL	NA	NA	NA	NA
WP_013087231.1\|73008_73560_+	hypothetical protein	NA	NA	NA	NA
WP_023338064.1\|73550_73967_+	hypothetical protein	NA	NA	NA	NA
WP_039025121.1\|74179_75157_-\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJ76	Virus_Rctr85	3.0e-47	39.4
80183:80198	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022148

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP022149

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection