CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017234	Bacillus cereus strain FORC_048 chromosome, complete genome	3 crisprs	cas3,csa3,WYL,c2c9_V-U4,DinG,DEDDh	0	5	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017234_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017234_2

3244728-3244880

Orphan

Consensus_repeat	Method
ACCAGTTGGACCGGTTGGACCAGT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP017234_2

>merge|NZ_CP017234|2|3244728-3244880|PILER-CR
ACCAGTTGGGCCGGTTGGACCATTTTCTCCTTGCACCCCTTGCACTCCTTGTATTCCTTGTGGGCCGGTTGGACCGATTGGACCTTGTACGCCTTGTATTCCTTGCGGTCCAGTTGGTCCACCTAAAGCACCAGTTGGACCGGTTGGACCAGT

>NZ_CP017234|2|1|3244728-3244880|PILER-CR
ACCAGTTGGGCCGGTTGGACCATT	TTCTCCTTGCACCCCTTGCACTCCTTGTATTCCTTGTGG
GCCGGTTGGACCGATTGGACCTTG	TACGCCTTGTATTCCTTGCGGTCCAGTTGGTCCACCTAAAGCACC
AGTTGGACCGGTTGGACCAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017234.1\|WP_000938438.1\|3252332_3252881_-\|DUF2179-domain-containing-protein	unknown	unknown	gnl\|CDD\|235234
NZ_CP017234.1\|WP_000355451.1\|3235958_3236798_+\|DUF2785-domain-containing-protein	unknown	unknown	gnl\|CDD\|371322
NZ_CP017234.1\|WP_046392906.1\|3247633_3248389_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP017234.1\|WP_000539727.1\|3241030_3241279_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP017234.1\|WP_000207371.1\|3235112_3235835_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP017234.1\|WP_000601226.1\|3241488_3241950_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP017234.1\|WP_000747695.1\|3251987_3252227_+\|DUF3923-family-protein	unknown	unknown	gnl\|CDD\|289806
NZ_CP017234.1\|WP_000945243.1\|3242227_3242371_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017234.1\|WP_000540463.1\|3236815_3237262_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240033
NZ_CP017234.1\|WP_006922529.1\|3248430_3248973_-\|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|378696
NZ_CP017234.1\|WP_000411484.1\|3239845_3240967_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP017234.1\|WP_044306796.1\|3250319_3251234_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP017234.1\|WP_000285635.1\|3254993_3255401_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133406
NZ_CP017234.1\|WP_044306797.1\|3251533_3251911_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017234.1\|WP_025708771.1\|3238658_3239816_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl\|CDD\|237107
NZ_CP017234.1\|WP_000402258.1\|3253545_3254874_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP017234.1\|WP_088867829.1\|3249085_3250279_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP017234.1\|WP_001290888.1\|3237270_3238269_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|183592
NZ_CP017234.1\|WP_000917826.1\|3234221_3235061_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017234.1\|WP_000613876.1\|3253079_3253493_-\|ATP-synthase-subunit-I	unknown	unknown	gnl\|CDD\|377159

Protein	Function_ID	Function_description	E-value
NZ_CP017234.1\|WP_000539727.1\|3241030_3241279_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	4.0876e-09
NZ_CP017234.1\|WP_046392906.1\|3247633_3248389_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.69473e-23
NZ_CP017234.1\|WP_000601226.1\|3241488_3241950_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.17689e-12
NZ_CP017234.1\|WP_000207371.1\|3235112_3235835_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.26343e-06
NZ_CP017234.1\|WP_000938438.1\|3252332_3252881_-\|DUF2179-domain-containing-protein	gnl\|CDD\|235234	PRK04164, PRK04164, hypothetical protein; Provisional.	6.88941e-83
NZ_CP017234.1\|WP_000747695.1\|3251987_3252227_+\|DUF3923-family-protein	gnl\|CDD\|289806	pfam13061, DUF3923, Protein of unknown function (DUF3923). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 80 amino acids in length.	4.27117e-12
NZ_CP017234.1\|WP_025708771.1\|3238658_3239816_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl\|CDD\|237107	PRK12464, PRK12464, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NZ_CP017234.1\|WP_088867829.1\|3249085_3250279_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.97289e-71
NZ_CP017234.1\|WP_006922529.1\|3248430_3248973_-\|CGNR-zinc-finger-domain-containing-protein	gnl\|CDD\|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	6.22959e-18
NZ_CP017234.1\|WP_000411484.1\|3239845_3240967_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.99865e-58
NZ_CP017234.1\|WP_044306796.1\|3250319_3251234_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	6.9097e-14
NZ_CP017234.1\|WP_000285635.1\|3254993_3255401_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133406	cd04779, HTH_MerR-like_sg4, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 4). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.12673e-60
NZ_CP017234.1\|WP_000613876.1\|3253079_3253493_-\|ATP-synthase-subunit-I	gnl\|CDD\|377159	pfam03899, ATP-synt_I, ATP synthase I chain. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI. AtpI is a Ca2+/Mg2+ transporter.	2.17218e-07
NZ_CP017234.1\|WP_000540463.1\|3236815_3237262_+\|NUDIX-hydrolase	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	5.58384e-60
NZ_CP017234.1\|WP_000402258.1\|3253545_3254874_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.44362e-160
NZ_CP017234.1\|WP_000355451.1\|3235958_3236798_+\|DUF2785-domain-containing-protein	gnl\|CDD\|371322	pfam10978, DUF2785, Protein of unknown function (DUF2785). Some members in this family are annotated as hypothetical membrane spanning proteins however this cannot be confirmed. The family has no known function.	1.69702e-39
NZ_CP017234.1\|WP_001290888.1\|3237270_3238269_-\|tryptophan--tRNA-ligase	gnl\|CDD\|183592	PRK12556, PRK12556, tryptophanyl-tRNA synthetase; Provisional.	0

>NZ_CP017234.1|WP_000945243.1|3242227_3242371_+|hypothetical-protein
MLRLSDHAIKMMEQRLRIEKQRTYQANKVVDNLHHKYFFQHIFQPKR
>NZ_CP017234.1|WP_000601226.1|3241488_3241950_+|GNAT-family-N-acetyltransferase
MILKLNSTSFEVATSILQVQIPAYKVEADYLNSTAIPRLYDTVNDIQNCVETFYGYFSENKLVGFISFVQEEKLIDIHRLVVSPDFFQKGIATKLLIYIFNMFPSPMTYIVQTGKANTPAITLYKKHGFITVSDTILPDGMILTQLKKTEYTK
>NZ_CP017234.1|WP_000539727.1|3241030_3241279_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGWIITLIVGAIIGAIASSITGKNFPGGMFGNIIAGLLGASLGGKLFGTFGPSFGGIHVVPALLGAIVLIFIVSFVVKAAKK
>NZ_CP017234.1|WP_000411484.1|3239845_3240967_-|AI-2E-family-transporter
MEKINIRKRDKLRKFFREQNYLAVLLGFALLFINILLLTKISFVFTPFIVFLKTIFFPVLLAGVLFYILHPFVSLLEKKGVSRIVSIASIYLIVLGLFVFLVVTVIPIIKDQIDALIDNLPYFGHEIEQAARRFGESNLLGKIQENLNINVANMVKEYTVDFTKSLSSVTGNVTGFLSTVTEVVLTFVMVPFILFYLLKDGEQLPNHFLKFISEQRQPAAMRILDDMHYAISSYIRGQIIVSLFIGIMLLIGYLIIGIKYAVLLAILAMIVNIVPYVGPIIAITPALIIAFIDSPAMVLKVIIVMMVVQLAEGKFISPQVMGKKLDIHPITIIFIILTAGNLFGIMGIILAIPGYAILKVLVTHGYRFVKLNT
>NZ_CP017234.1|WP_025708771.1|3238658_3239816_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MVKYISILGSTGSIGTSALDVVSAHPEHFKIVGLTANYNIDLLEQQIKTFQPRIVSVATKDLADKLRTRISANTKITHGTDGLIAVATHPDSNLVLSSVVGVSGLLPTIEALKAKKDIAIANKETLVAAGHIVTELAKQNGCRLIPVDSEHSAIFQCLNGENNKEIEKLIVTASGGAFRDKTRDEMQTLQAKDALKHPNWLMGAKLTIDSATLMNKGFEVMEARWLFDIPYEKINVMIHKESIIHSLVEFIDGSVMAQLGAPDMRMPIQYAFHYPTRLPSSYEKLNLLEIGSLHFEKPDLEKFPCLQYAYECGKIGGTTPAVLNAANEIANALFLKNEIAFFDIEKTIYKTIEAHHNVKDPSLDAILEADQWARQYANELLIKKR
>NZ_CP017234.1|WP_001290888.1|3237270_3238269_-|tryptophan--tRNA-ligase
MSEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGKALYFIADYHALNAVHDSEKFSSYTKEVAATWLSLGLGEDVIFYRQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGLYTYPILMAADILLFQATHVPVGKDQIQHIEIARDIATYFNHTFGTTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELETLFTIYKEFATEDEIQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAIYMNEPDLLYEALENGAEKARAIAKVNLAEIKKRIGFKRER
>NZ_CP017234.1|WP_000540463.1|3236815_3237262_+|NUDIX-hydrolase
MGYIEDMRNLVGNHPLILIGSHAIILNEKDEVLLQLRTDFNRWGIIGGALEYNETLEDALKREVYEETGLIIKNPELFRTYSGPDYFQIYPNGDQVHGVLVVYICREFHGELVCDQSESKELRFFSLDELPNNLPPVIERIITDYQKK
>NZ_CP017234.1|WP_000355451.1|3235958_3236798_+|DUF2785-domain-containing-protein
MDITALQQQLELIQQNDYTQLQHIDVNELTLNMLQYIGTTDSYVRYQLIYKCFAHFIHHEFLMDDQLKLLLQTCLSDEYLYCDIYSPHTDGVFTRSYTVSLIALILQFANSHYFCTEEDIEEIKNKLITYTNLETDFRGYIENKGWAHCLAHVSDAFTEIVHNTYTTFEWYEELIHCLLNKIFIPSDLFHNNEDERIVTPLLAMLYHDFPQNDLISIIHKKIKRLPQIRKRLSLNEYCILCANIKTFLRTLFFRTKDDHNLAFTARKTERMLKELPNYY
>NZ_CP017234.1|WP_000207371.1|3235112_3235835_-|GNAT-family-N-acetyltransferase
MTTIEQLEKHFKIRRNASSIMIKENNAEIFTEEQLEEMMQYCVAEAKKDGLEKLHFEISSKSPNYDVYKRCFETYLFEYVTENMIVFKDIYEVEDVESEIDFKLIEEVGEEAFYSLWNEATGEPVAHDQFVHMMLQEIGEQWKEHCLTASADEEPIGIVIPHIERGTLEEGKLMYFAVTPNMRNKGYEAALFAGAMFVLKEIGASYYIGETNMQNEWMKDVFEKNGCQLLSCTERYVRKF
>NZ_CP017234.1|WP_000917826.1|3234221_3235061_-|hypothetical-protein
MLKQSMHSFVLLYPNVLLEGWNVEKVSERYEGEKWGTFWFQVVTPTGMFRVKEFFLDIMEPVFPDSCISQAKGDCFQYKGLVYWKGINYKGKESYVTSIWKTQVEISVDHGYVKQDEMERFLFELQPVNMELGKTILHTSFHLLSFQAKRSEMGEIGRCREWNAPDDVSYVNLLIHEKLNWKLESVGFGNDETQYVYWDEVNKLYALWVCRHKNKAYYPISSWTMNYGPKQIINGLEFYSHPNRGTVVYEDLGNEQIAYVFRGNPCTNFEQVKELFACL
>NZ_CP017234.1|WP_046392906.1|3247633_3248389_-|class-I-SAM-dependent-methyltransferase
MKGTQMLALNKKCWDTVAPYFFQVDCLPKYGPYTASEDEIRLFDSIRKKKVLDIGCGSGHSLQYMAEQGAEELWGLDLSSTQIEIANKTLKEWNPKLVCGAMEEEGDIPKGYFDIVYSIYALGWTLDLRKTLELIYSYVKPGGSFIFSWEHPVYSNLQYGTEEVAIKSSYHKETPITFETFKGENVQATLYKRKISTYINELNRAGFKIERIEEPEPSSAFDGELAEPSTKYYSLYKARMVPTTFIIKARK
>NZ_CP017234.1|WP_006922529.1|3248430_3248973_-|CGNR-zinc-finger-domain-containing-protein
MNQNAPNELEHIREFLNTWRIPNDTREPIDLLQTEEDIKLFMKEYFDEEFPFHTIEELRGFREDIRMTIEGEGSLQKWLEKYPFHVHIKDDMKDITYEPVYEENVYTKVLSIVLMSIQENVWGRLKACPDCRWVFYDHSRNGSKRWCGMYAGEEGGRACGTIAKVKNYRAKRKGRSGYDM
>NZ_CP017234.1|WP_088867829.1|3249085_3250279_+|MFS-transporter
MKSFSTPIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAVQVGTVLTVMTITSRVIPLFSGLIADKIGYIIMMIAGLFLRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIFGSQPTHLRKNLFTYLNLSFNCGAIIGPIAGGFLLLLDPLYAFSLTGSLMLLFAFIFYLLKNHFQVTTENTSITLGIQAILQNKYFLLFSFIMIFFYIMFTQLTVALPLHMKNISNSNQLATLVITINAITGVLFMVLFRKLFYKYNTLSIIKYGVLLMSISFLLIPLFQHPYWLFICVILFTIGETLVLPNADIAIANYSNESYTATFFGFYQLSLAFGFIIGNYTGTSFTSNLSGMYTPWLIFGGIGLIGFISLHILNIKKVASKEDIHLCNTSDL
>NZ_CP017234.1|WP_044306796.1|3250319_3251234_-|tetratricopeptide-repeat-protein
MNINEKAIEMFEQNKYEEAMELFQQAVHESRDLQSLNNLAWMYFYEEENDDKALELIREVVKLNPSSYFPYNILGDIYMKQEKWTEAKEALQKSISIQPSDEAYHNVAVAHYNLGELEKASEFFLRVAGDSDYIMYSYVKCLIDLERTTEAKEKLDTFNRESDNFLGEIHVADLYVELNCYKEAIEWFEKGYKKCWKSPNWIGRFVYALYKTNNFSRINEVIRESIEAKTAEIEDVQNEEVEENWTENDKKELIEEYTEENNCYKTMVERIKSGYVPGLEFETDYIGGCYLFGCKRHNHLEYEK
>NZ_CP017234.1|WP_044306797.1|3251533_3251911_+|hypothetical-protein
MKRKLLVLLFTGIILSGCSTIAENSLESGKGSMELLTPTITAKDNELEIKTEGIDENKVTFIYVANKKVLEQKLKNGESYKLNIKDIEHAHRTDYKPKVQLLQTKDDNDDGEILTFKQVRYTVKN
>NZ_CP017234.1|WP_000747695.1|3251987_3252227_+|DUF3923-family-protein
MKKRWISWWIGNLFWIIVFGIWAAIIWLREVDGAGVIQTPEIKSISLIVILIAFIIPVFFQVIWLIINLRMSRKNNYTI
>NZ_CP017234.1|WP_000938438.1|3252332_3252881_-|DUF2179-domain-containing-protein
MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAGVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDEHAS
>NZ_CP017234.1|WP_000613876.1|3253079_3253493_-|ATP-synthase-subunit-I
MIQEALRVYRLQLYVIFSGLLLMWTITPFGKQVTGFGIGLAVSAYCLWLLARRVEKLGKSIVMKEKAPGLGVLNRFAAAILGAIIMYEIEHEMEMWAFGTGILGGHFLMIANLAYANMQLVKEEEKQREHASKNIEL
>NZ_CP017234.1|WP_000402258.1|3253545_3254874_-|HlyC/CorC-family-transporter
MEIFNLVMVAILIAFTGFFVAAEFAIVKIRSSRIDQLVAEGKRGALAAKKVTTNLDEYLSACQLGITVTAMGLGWLGEPTIEKLLHPLFEKWNLNPSISSVLTFGLAFMIMTYLHVVVGELAPKTMAIQKAERVTLLLAGPLMMFYKVMYPFIWVLNGSARVITGLFGLKPASEHEVAHTEEELRLILSDSYESGEINQAEYKYVNNIFEFDNRIAKEIMVPRTEIVGFYLEDSVEEHMKVIQNERYTRYPIFGEDKDDIIGMVNVKDFFIRYMTEDQKDLSSIRSYMRPIIEVMETTPIHDLLLQMQKKRIPMAVLYDEYGGTAGIVTLEDILEEIVGEIRDEYDEDEAPPIQHVNEQHIIVDGKVLISEVKDLFGLHIEEDDVDTIGGWIMMQNHEIEEGQHVEAEGYEFKVLEKDAYQIKRVEIRKMEQEQEEEKAATV
>NZ_CP017234.1|WP_000285635.1|3254993_3255401_-|MerR-family-transcriptional-regulator
MYRIGQLALMAHVSKRTIDYYTNLGILKAERSQSNYRYYDETAFETLQFIEKCKEMHMPLCEIKEKIEEKKKLLGINEHVSKQVNEVTDHIHQLEVELTELKPLLDGLTDSQREKISKSLSGQTTALIQTLALLL

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Crispr_ID: NZ_CP017234_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017234_1

3243541-3243920

Orphan

Consensus_repeat	Method
CCTTGNNNACCNGTTGGACC	CRT

7 spacers

The CRISPR arrays of NZ_CP017234_1

>merge|NZ_CP017234|1|3243541-3243920|CRT
CCTTGAGGACCAGTTGGACCTGTTATGCCACTCGGACCTTGTACGCCTTGCACTCCTTGAGGACCGGTTGGACCACTCGGACCTTGGATTCCTTGTAGCCCCTGTAAACCAGTTGGACCTGTCGCTCCCCTTACTCCTTGCTCACCTTGTATGCCTTGTATCCCTTGAGGGCCAGTTGGACCGATTGGCCCCTGTGCCCCTTGCACTCCTTGTGGACCAGTCGGACCGGTTGCTCCTACCGGTCCCTGGATTCCTTGTAGACCTTGCGGACCAGTCGGACCGGTTACTCCTTGTATCCCTTGTGGACCTTGAATGCCTTGATCACCCGTTGGACCCGTTGCCCCCATTGGTCCCTGTACTCCTTGCAAACCTGTTACACC

>NZ_CP017234|1|1|3243541-3243920|CRT
CCTTGAGGACCAGTTGGACC	TGTTATGCCACTCGGACCTTGTACGCCTTGCACT
CCTTGAGGACCGGTTGGACC	ACTCGGACCTTGGATTCCTTGTAGC
CCCTGTAAACCAGTTGGACC	TGTCGCTCCCCTTACTCCTTGCTCACCTTGTATGCCTTGTATC
CCTTGAGGGCCAGTTGGACC	GATTGGCCCCTGTGCCCCTTGCACT
CCTTGTGGACCAGTCGGACC	GGTTGCTCCTACCGGTCCCTGGATTCCTTGTAGA
CCTTGCGGACCAGTCGGACC	GGTTACTCCTTGTATCCCTTGTGGACCTTGAATG
CCTTGATCACCCGTTGGACC	CGTTGCCCCCATTGGTCCCTGTACT
CCTTGCAAACCTGTTACACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017234.1\|WP_000938438.1\|3252332_3252881_-\|DUF2179-domain-containing-protein	unknown	unknown	gnl\|CDD\|235234
NZ_CP017234.1\|WP_000355451.1\|3235958_3236798_+\|DUF2785-domain-containing-protein	unknown	unknown	gnl\|CDD\|371322
NZ_CP017234.1\|WP_046392906.1\|3247633_3248389_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP017234.1\|WP_000539727.1\|3241030_3241279_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP017234.1\|WP_000207371.1\|3235112_3235835_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP017234.1\|WP_000601226.1\|3241488_3241950_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP017234.1\|WP_000747695.1\|3251987_3252227_+\|DUF3923-family-protein	unknown	unknown	gnl\|CDD\|289806
NZ_CP017234.1\|WP_000945243.1\|3242227_3242371_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017234.1\|WP_000540463.1\|3236815_3237262_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240033
NZ_CP017234.1\|WP_006922529.1\|3248430_3248973_-\|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|378696
NZ_CP017234.1\|WP_000411484.1\|3239845_3240967_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP017234.1\|WP_044306796.1\|3250319_3251234_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP017234.1\|WP_000285635.1\|3254993_3255401_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133406
NZ_CP017234.1\|WP_044306797.1\|3251533_3251911_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017234.1\|WP_025708771.1\|3238658_3239816_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl\|CDD\|237107
NZ_CP017234.1\|WP_000402258.1\|3253545_3254874_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP017234.1\|WP_088867829.1\|3249085_3250279_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP017234.1\|WP_001290888.1\|3237270_3238269_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|183592
NZ_CP017234.1\|WP_000917826.1\|3234221_3235061_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017234.1\|WP_000613876.1\|3253079_3253493_-\|ATP-synthase-subunit-I	unknown	unknown	gnl\|CDD\|377159

Protein	Function_ID	Function_description	E-value
NZ_CP017234.1\|WP_000539727.1\|3241030_3241279_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	4.0876e-09
NZ_CP017234.1\|WP_046392906.1\|3247633_3248389_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.69473e-23
NZ_CP017234.1\|WP_000601226.1\|3241488_3241950_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.17689e-12
NZ_CP017234.1\|WP_000207371.1\|3235112_3235835_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.26343e-06
NZ_CP017234.1\|WP_000938438.1\|3252332_3252881_-\|DUF2179-domain-containing-protein	gnl\|CDD\|235234	PRK04164, PRK04164, hypothetical protein; Provisional.	6.88941e-83
NZ_CP017234.1\|WP_000747695.1\|3251987_3252227_+\|DUF3923-family-protein	gnl\|CDD\|289806	pfam13061, DUF3923, Protein of unknown function (DUF3923). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 80 amino acids in length.	4.27117e-12
NZ_CP017234.1\|WP_025708771.1\|3238658_3239816_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl\|CDD\|237107	PRK12464, PRK12464, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NZ_CP017234.1\|WP_088867829.1\|3249085_3250279_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.97289e-71
NZ_CP017234.1\|WP_006922529.1\|3248430_3248973_-\|CGNR-zinc-finger-domain-containing-protein	gnl\|CDD\|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	6.22959e-18
NZ_CP017234.1\|WP_000411484.1\|3239845_3240967_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.99865e-58
NZ_CP017234.1\|WP_044306796.1\|3250319_3251234_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	6.9097e-14
NZ_CP017234.1\|WP_000285635.1\|3254993_3255401_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133406	cd04779, HTH_MerR-like_sg4, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 4). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.12673e-60
NZ_CP017234.1\|WP_000613876.1\|3253079_3253493_-\|ATP-synthase-subunit-I	gnl\|CDD\|377159	pfam03899, ATP-synt_I, ATP synthase I chain. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI. AtpI is a Ca2+/Mg2+ transporter.	2.17218e-07
NZ_CP017234.1\|WP_000540463.1\|3236815_3237262_+\|NUDIX-hydrolase	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	5.58384e-60
NZ_CP017234.1\|WP_000402258.1\|3253545_3254874_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.44362e-160
NZ_CP017234.1\|WP_000355451.1\|3235958_3236798_+\|DUF2785-domain-containing-protein	gnl\|CDD\|371322	pfam10978, DUF2785, Protein of unknown function (DUF2785). Some members in this family are annotated as hypothetical membrane spanning proteins however this cannot be confirmed. The family has no known function.	1.69702e-39
NZ_CP017234.1\|WP_001290888.1\|3237270_3238269_-\|tryptophan--tRNA-ligase	gnl\|CDD\|183592	PRK12556, PRK12556, tryptophanyl-tRNA synthetase; Provisional.	0

>NZ_CP017234.1|WP_000945243.1|3242227_3242371_+|hypothetical-protein
MLRLSDHAIKMMEQRLRIEKQRTYQANKVVDNLHHKYFFQHIFQPKR
>NZ_CP017234.1|WP_000601226.1|3241488_3241950_+|GNAT-family-N-acetyltransferase
MILKLNSTSFEVATSILQVQIPAYKVEADYLNSTAIPRLYDTVNDIQNCVETFYGYFSENKLVGFISFVQEEKLIDIHRLVVSPDFFQKGIATKLLIYIFNMFPSPMTYIVQTGKANTPAITLYKKHGFITVSDTILPDGMILTQLKKTEYTK
>NZ_CP017234.1|WP_000539727.1|3241030_3241279_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGWIITLIVGAIIGAIASSITGKNFPGGMFGNIIAGLLGASLGGKLFGTFGPSFGGIHVVPALLGAIVLIFIVSFVVKAAKK
>NZ_CP017234.1|WP_000411484.1|3239845_3240967_-|AI-2E-family-transporter
MEKINIRKRDKLRKFFREQNYLAVLLGFALLFINILLLTKISFVFTPFIVFLKTIFFPVLLAGVLFYILHPFVSLLEKKGVSRIVSIASIYLIVLGLFVFLVVTVIPIIKDQIDALIDNLPYFGHEIEQAARRFGESNLLGKIQENLNINVANMVKEYTVDFTKSLSSVTGNVTGFLSTVTEVVLTFVMVPFILFYLLKDGEQLPNHFLKFISEQRQPAAMRILDDMHYAISSYIRGQIIVSLFIGIMLLIGYLIIGIKYAVLLAILAMIVNIVPYVGPIIAITPALIIAFIDSPAMVLKVIIVMMVVQLAEGKFISPQVMGKKLDIHPITIIFIILTAGNLFGIMGIILAIPGYAILKVLVTHGYRFVKLNT
>NZ_CP017234.1|WP_025708771.1|3238658_3239816_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MVKYISILGSTGSIGTSALDVVSAHPEHFKIVGLTANYNIDLLEQQIKTFQPRIVSVATKDLADKLRTRISANTKITHGTDGLIAVATHPDSNLVLSSVVGVSGLLPTIEALKAKKDIAIANKETLVAAGHIVTELAKQNGCRLIPVDSEHSAIFQCLNGENNKEIEKLIVTASGGAFRDKTRDEMQTLQAKDALKHPNWLMGAKLTIDSATLMNKGFEVMEARWLFDIPYEKINVMIHKESIIHSLVEFIDGSVMAQLGAPDMRMPIQYAFHYPTRLPSSYEKLNLLEIGSLHFEKPDLEKFPCLQYAYECGKIGGTTPAVLNAANEIANALFLKNEIAFFDIEKTIYKTIEAHHNVKDPSLDAILEADQWARQYANELLIKKR
>NZ_CP017234.1|WP_001290888.1|3237270_3238269_-|tryptophan--tRNA-ligase
MSEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGKALYFIADYHALNAVHDSEKFSSYTKEVAATWLSLGLGEDVIFYRQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGLYTYPILMAADILLFQATHVPVGKDQIQHIEIARDIATYFNHTFGTTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELETLFTIYKEFATEDEIQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAIYMNEPDLLYEALENGAEKARAIAKVNLAEIKKRIGFKRER
>NZ_CP017234.1|WP_000540463.1|3236815_3237262_+|NUDIX-hydrolase
MGYIEDMRNLVGNHPLILIGSHAIILNEKDEVLLQLRTDFNRWGIIGGALEYNETLEDALKREVYEETGLIIKNPELFRTYSGPDYFQIYPNGDQVHGVLVVYICREFHGELVCDQSESKELRFFSLDELPNNLPPVIERIITDYQKK
>NZ_CP017234.1|WP_000355451.1|3235958_3236798_+|DUF2785-domain-containing-protein
MDITALQQQLELIQQNDYTQLQHIDVNELTLNMLQYIGTTDSYVRYQLIYKCFAHFIHHEFLMDDQLKLLLQTCLSDEYLYCDIYSPHTDGVFTRSYTVSLIALILQFANSHYFCTEEDIEEIKNKLITYTNLETDFRGYIENKGWAHCLAHVSDAFTEIVHNTYTTFEWYEELIHCLLNKIFIPSDLFHNNEDERIVTPLLAMLYHDFPQNDLISIIHKKIKRLPQIRKRLSLNEYCILCANIKTFLRTLFFRTKDDHNLAFTARKTERMLKELPNYY
>NZ_CP017234.1|WP_000207371.1|3235112_3235835_-|GNAT-family-N-acetyltransferase
MTTIEQLEKHFKIRRNASSIMIKENNAEIFTEEQLEEMMQYCVAEAKKDGLEKLHFEISSKSPNYDVYKRCFETYLFEYVTENMIVFKDIYEVEDVESEIDFKLIEEVGEEAFYSLWNEATGEPVAHDQFVHMMLQEIGEQWKEHCLTASADEEPIGIVIPHIERGTLEEGKLMYFAVTPNMRNKGYEAALFAGAMFVLKEIGASYYIGETNMQNEWMKDVFEKNGCQLLSCTERYVRKF
>NZ_CP017234.1|WP_000917826.1|3234221_3235061_-|hypothetical-protein
MLKQSMHSFVLLYPNVLLEGWNVEKVSERYEGEKWGTFWFQVVTPTGMFRVKEFFLDIMEPVFPDSCISQAKGDCFQYKGLVYWKGINYKGKESYVTSIWKTQVEISVDHGYVKQDEMERFLFELQPVNMELGKTILHTSFHLLSFQAKRSEMGEIGRCREWNAPDDVSYVNLLIHEKLNWKLESVGFGNDETQYVYWDEVNKLYALWVCRHKNKAYYPISSWTMNYGPKQIINGLEFYSHPNRGTVVYEDLGNEQIAYVFRGNPCTNFEQVKELFACL
>NZ_CP017234.1|WP_046392906.1|3247633_3248389_-|class-I-SAM-dependent-methyltransferase
MKGTQMLALNKKCWDTVAPYFFQVDCLPKYGPYTASEDEIRLFDSIRKKKVLDIGCGSGHSLQYMAEQGAEELWGLDLSSTQIEIANKTLKEWNPKLVCGAMEEEGDIPKGYFDIVYSIYALGWTLDLRKTLELIYSYVKPGGSFIFSWEHPVYSNLQYGTEEVAIKSSYHKETPITFETFKGENVQATLYKRKISTYINELNRAGFKIERIEEPEPSSAFDGELAEPSTKYYSLYKARMVPTTFIIKARK
>NZ_CP017234.1|WP_006922529.1|3248430_3248973_-|CGNR-zinc-finger-domain-containing-protein
MNQNAPNELEHIREFLNTWRIPNDTREPIDLLQTEEDIKLFMKEYFDEEFPFHTIEELRGFREDIRMTIEGEGSLQKWLEKYPFHVHIKDDMKDITYEPVYEENVYTKVLSIVLMSIQENVWGRLKACPDCRWVFYDHSRNGSKRWCGMYAGEEGGRACGTIAKVKNYRAKRKGRSGYDM
>NZ_CP017234.1|WP_088867829.1|3249085_3250279_+|MFS-transporter
MKSFSTPIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAVQVGTVLTVMTITSRVIPLFSGLIADKIGYIIMMIAGLFLRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIFGSQPTHLRKNLFTYLNLSFNCGAIIGPIAGGFLLLLDPLYAFSLTGSLMLLFAFIFYLLKNHFQVTTENTSITLGIQAILQNKYFLLFSFIMIFFYIMFTQLTVALPLHMKNISNSNQLATLVITINAITGVLFMVLFRKLFYKYNTLSIIKYGVLLMSISFLLIPLFQHPYWLFICVILFTIGETLVLPNADIAIANYSNESYTATFFGFYQLSLAFGFIIGNYTGTSFTSNLSGMYTPWLIFGGIGLIGFISLHILNIKKVASKEDIHLCNTSDL
>NZ_CP017234.1|WP_044306796.1|3250319_3251234_-|tetratricopeptide-repeat-protein
MNINEKAIEMFEQNKYEEAMELFQQAVHESRDLQSLNNLAWMYFYEEENDDKALELIREVVKLNPSSYFPYNILGDIYMKQEKWTEAKEALQKSISIQPSDEAYHNVAVAHYNLGELEKASEFFLRVAGDSDYIMYSYVKCLIDLERTTEAKEKLDTFNRESDNFLGEIHVADLYVELNCYKEAIEWFEKGYKKCWKSPNWIGRFVYALYKTNNFSRINEVIRESIEAKTAEIEDVQNEEVEENWTENDKKELIEEYTEENNCYKTMVERIKSGYVPGLEFETDYIGGCYLFGCKRHNHLEYEK
>NZ_CP017234.1|WP_044306797.1|3251533_3251911_+|hypothetical-protein
MKRKLLVLLFTGIILSGCSTIAENSLESGKGSMELLTPTITAKDNELEIKTEGIDENKVTFIYVANKKVLEQKLKNGESYKLNIKDIEHAHRTDYKPKVQLLQTKDDNDDGEILTFKQVRYTVKN
>NZ_CP017234.1|WP_000747695.1|3251987_3252227_+|DUF3923-family-protein
MKKRWISWWIGNLFWIIVFGIWAAIIWLREVDGAGVIQTPEIKSISLIVILIAFIIPVFFQVIWLIINLRMSRKNNYTI
>NZ_CP017234.1|WP_000938438.1|3252332_3252881_-|DUF2179-domain-containing-protein
MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAGVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDEHAS
>NZ_CP017234.1|WP_000613876.1|3253079_3253493_-|ATP-synthase-subunit-I
MIQEALRVYRLQLYVIFSGLLLMWTITPFGKQVTGFGIGLAVSAYCLWLLARRVEKLGKSIVMKEKAPGLGVLNRFAAAILGAIIMYEIEHEMEMWAFGTGILGGHFLMIANLAYANMQLVKEEEKQREHASKNIEL
>NZ_CP017234.1|WP_000402258.1|3253545_3254874_-|HlyC/CorC-family-transporter
MEIFNLVMVAILIAFTGFFVAAEFAIVKIRSSRIDQLVAEGKRGALAAKKVTTNLDEYLSACQLGITVTAMGLGWLGEPTIEKLLHPLFEKWNLNPSISSVLTFGLAFMIMTYLHVVVGELAPKTMAIQKAERVTLLLAGPLMMFYKVMYPFIWVLNGSARVITGLFGLKPASEHEVAHTEEELRLILSDSYESGEINQAEYKYVNNIFEFDNRIAKEIMVPRTEIVGFYLEDSVEEHMKVIQNERYTRYPIFGEDKDDIIGMVNVKDFFIRYMTEDQKDLSSIRSYMRPIIEVMETTPIHDLLLQMQKKRIPMAVLYDEYGGTAGIVTLEDILEEIVGEIRDEYDEDEAPPIQHVNEQHIIVDGKVLISEVKDLFGLHIEEDDVDTIGGWIMMQNHEIEEGQHVEAEGYEFKVLEKDAYQIKRVEIRKMEQEQEEEKAATV
>NZ_CP017234.1|WP_000285635.1|3254993_3255401_-|MerR-family-transcriptional-regulator
MYRIGQLALMAHVSKRTIDYYTNLGILKAERSQSNYRYYDETAFETLQFIEKCKEMHMPLCEIKEKIEEKKKLLGINEHVSKQVNEVTDHIHQLEVELTELKPLLDGLTDSQREKISKSLSGQTTALIQTLALLL

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Crispr_ID: NZ_CP017234_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017234_3

5140939-5141072

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP017234_3

>merge|NZ_CP017234|3|5140939-5141072|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGGTTCTTCTTTTTTGTCACTAGTTGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP017234|3|1|5140939-5141072|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGG	TTCTTCTTTTTTGTCACTAGTTGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017234.1\|WP_006926555.1\|5141960_5142668_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP017234.1\|WP_071739766.1\|5135983_5136727_-\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP017234.1\|WP_000457978.1\|5138873_5139875_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP017234.1\|WP_000411274.1\|5146022_5147327_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP017234.1\|WP_088868010.1\|5134412_5135180_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP017234.1\|WP_088867985.1\|5133282_5134164_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP017234.1\|WP_000544012.1\|5140035_5140308_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP017234.1\|WP_044306737.1\|5142667_5143510_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP017234.1\|WP_046393107.1\|5150083_5151586_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP017234.1\|WP_061139594.1\|5136985_5137663_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP017234.1\|WP_000008901.1\|5140616_5140751_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017234.1\|WP_000672663.1\|5144796_5145816_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP017234.1\|WP_088867986.1\|5148122_5148359_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP017234.1\|WP_000367481.1\|5148561_5150082_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP017234.1\|WP_071739763.1\|5131413_5133222_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP017234.1\|WP_002005985.1\|5147366_5148077_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP017234.1\|WP_044306738.1\|5143691_5144699_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP017234.1\|WP_061457913.1\|5135292_5135994_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP017234.1\|WP_000931953.1\|5138009_5138444_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP017234.1\|WP_025709674.1\|5151582_5153445_-\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836

Protein	Function_ID	Function_description	E-value
NZ_CP017234.1\|WP_006926555.1\|5141960_5142668_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	5.40923e-09
NZ_CP017234.1\|WP_071739766.1\|5135983_5136727_-\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	4.41597e-84
NZ_CP017234.1\|WP_000457978.1\|5138873_5139875_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP017234.1\|WP_000411274.1\|5146022_5147327_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP017234.1\|WP_088868010.1\|5134412_5135180_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	2.5572e-107
NZ_CP017234.1\|WP_088867985.1\|5133282_5134164_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP017234.1\|WP_000544012.1\|5140035_5140308_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP017234.1\|WP_044306737.1\|5142667_5143510_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.2275e-88
NZ_CP017234.1\|WP_046393107.1\|5150083_5151586_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	1.22741e-177
NZ_CP017234.1\|WP_061139594.1\|5136985_5137663_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.04629e-81
NZ_CP017234.1\|WP_000672663.1\|5144796_5145816_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	5.80584e-135
NZ_CP017234.1\|WP_088867986.1\|5148122_5148359_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	1.04803e-22
NZ_CP017234.1\|WP_000367481.1\|5148561_5150082_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	4.78994e-150
NZ_CP017234.1\|WP_071739763.1\|5131413_5133222_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP017234.1\|WP_002005985.1\|5147366_5148077_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	5.16446e-34
NZ_CP017234.1\|WP_044306738.1\|5143691_5144699_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.41455e-32
NZ_CP017234.1\|WP_061457913.1\|5135292_5135994_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	8.97752e-84
NZ_CP017234.1\|WP_000931953.1\|5138009_5138444_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	1.13995e-94
NZ_CP017234.1\|WP_025709674.1\|5151582_5153445_-\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0

>NZ_CP017234.1|WP_000008901.1|5140616_5140751_-|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEEFEREE
>NZ_CP017234.1|WP_000544012.1|5140035_5140308_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP017234.1|WP_000457978.1|5138873_5139875_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP017234.1|WP_000931953.1|5138009_5138444_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAIGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP017234.1|WP_061139594.1|5136985_5137663_-|CpsD/CapB-family-tyrosine-protein-kinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHVRSIIVTSADPGDGKTTTISNLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKLLGVILNDKREEKEQYGYY
>NZ_CP017234.1|WP_071739766.1|5135983_5136727_-|capsular-biosynthesis-protein
MEETISLKELFHILKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGAMIQAGEVQTNIQLTNTYKVIIKSPVILEQVNEKLNLNMTAQELTKKVNVTNEKDSQVIAVTAEDKDPKRASDIANATADVFKGEVAKIMNVDNVTVISKAEVAENQSPIKPAPMLNVAIAFIVGLMASVGLAFLLEYLDNTVKKEEDVESLLGLPVLGIVARMDEETMNVKSHAPSSRKVRGQTIGS
>NZ_CP017234.1|WP_061457913.1|5135292_5135994_-|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAVDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTHSERLEKCVQTTSVDNLHFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASILVVRSESTEKETAVKAKGLLESAKGKLLGVVLNDRERENGLYYYYGAN
>NZ_CP017234.1|WP_088868010.1|5134412_5135180_-|tyrosine-protein-phosphatase
MIDLHCHILPGIDDGAQTVTDSLAMAQQAVSEGILTIVATPHHQNGKYVNERTSIIHHVKQLNDELQQHNIPLTILPGQEVRLYGDLLEDYEAGKIVTLNETNKYIFIEFPSNHVPRYAEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNLVNKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMVASDAHNTTSRGFHLAESYELIEKEFGMNVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP017234.1|WP_088867985.1|5133282_5134164_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPVTKAMPKEMLPIVDKPTIQYIVEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQSLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTHSSVIGVQTVPENETHRYGIIDPVEQNDRRYQVRQFVEKPAQGAAPSNLAIMGRYILTPEIFMLLEDQQTGAGGEIQLTDAIQRLNEVQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQNEELNVELMKYMKELVKKEEVHS
>NZ_CP017234.1|WP_071739763.1|5131413_5133222_-|polysaccharide-biosynthesis-protein
MSYRKRLSLLILLDSFIVLTAVYLSYWFVHPNVLNKIPTTVIISSITLLCSHHIFAAIYKLYNKAWEYASIGELKQIFKAITLSIIVTAIVQQIINHDIYVRILAIAWMLHLLLIGGSRFVWRMFRDTYITKATDKKRTLIIGAGSAGTMVVRQLQHNKEADLYPIAFVDDDRNKQKLEIYNVPVVGTTTHIQEIVEDNDIEHIIIAIPSLNRSQINEIFEKCRKTKAKTQIVPMLEDLLDGKLSVNEFRDVQVEDLLGREPIKLDDAGIGEKITGKTILVTGAGGSIGSEICRQVMKYKPAKIVLLGHGENSIYNIEMEMRVTYKDSVEITTEIADIQDRHKIFEIMKKHQPYIVYHAAAHKHVPLMERNPEEAVKNNIFGTKNVAEAADTFKVNTFVMVSTDKAVNPTNVMGATKRFAEMLVQHLAAVSTNTRFVAVRFGNVLGSRGSVIPLFKKQIQKGGPVTVTHPDMIRYFMTIPEASRLVIQAGTLARGGELFVLDMGDPVKIVDLAKNLITLSGFSIEEIGIEFTGLRPGEKMYEELLNEGEIHPEQVFPKIHIGKAVLIDSMILRQFMDEFENMAKEEIRIRLLDIANTKKVVK
>NZ_CP017234.1|WP_006926555.1|5141960_5142668_-|ABC-transporter-permease
MTFSMKRFSAIVRKEISDAGKNSQVILMALLPILLAVFYSNMDSIKEFFAGFIIVMTITMVGSYVQAIIIAEEKEKHTLRVLMLSPASPIEVILGKSVLTVFFVLASSFISLVILDTFKGNISMLVIIILIGTLLCVVLGTIVGLLSQNIAQTSILGLPIFIIFIMGPMLQEMVKNEFIIKVVKLLPTNHVMEALQKVIKGEGFIAIQEHILNNTIWTICLIILCIIVYKKKQLD
>NZ_CP017234.1|WP_044306737.1|5142667_5143510_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFDGKTALGNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLAQVNLLDDKKTPVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNEEGTTIFLTTHNMDEAETLCNRIAFLCGGEIVALDTPENLRLQYAKDQIEVVLKGKRKEVVQKDELGANRISEWMKKGELLSIHSHEPTLGDIFIEVTGRGL
>NZ_CP017234.1|WP_044306738.1|5143691_5144699_-|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein
MALLELKQLEKTNQLPEIELKVEKGQCIVLQCNNHTAKVLHRIIIGEEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYESKISIEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRMMIHNPDLVILEEPEQNVDIESTIIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEVEEVGEEKVIQMIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLSELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP017234.1|WP_000672663.1|5144796_5145816_-|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVETLPVEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGGKKNNADVTDTVKDQVYKSKDELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVEIKTMNDYEGKLMVKK
>NZ_CP017234.1|WP_000411274.1|5146022_5147327_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVAATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVNFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP017234.1|WP_002005985.1|5147366_5148077_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVLFLVGYREMKPISDEQKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKEKANIQKWEVEQSPDGYKATSYKKLSSYEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQNMNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP017234.1|WP_088867986.1|5148122_5148359_-|DUF1146-domain-containing-protein
MAQLLGQQVLIAIVSHLLFITITWWALQGIHIERLMKSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP017234.1|WP_000367481.1|5148561_5150082_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKSRASNEAAMKYVISGGIGTAIALFGMSYLYGITGSTNIIDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGAATPVTAFLGTISKIAGFLLIIRLFLMIFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNIKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQNNEENITIFTGLYKRSPFTAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP017234.1|WP_046393107.1|5150083_5151586_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAAVLACTYASGKNLSLFDEKMKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLATLAAIAAFSIKRNLKAFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIVELKEILRSVNAEGALVIPSSLQLSVFIAIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDVATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLAALNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSDITALGGLAKSVPVLSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK
>NZ_CP017234.1|WP_025709674.1|5151582_5153445_-|NADH-quinone-oxidoreductase-subunit-L
MIDYAWLIPLFPLVSFLLLIIFGKKIREGSSVLSIFFVFLSFILAVLVLIERFSETSVKHKWVWLRAGDVDISFGFEVTALGALMLFIVTLVSLLVHVYSKGYMKGDERLPTFYAYLGLFTFAMLGLVISTNLLQLYIFWELVGLGSFLLIGFYFFKEEAKAAAKKAFIMTRIGDVGLFIGMILIFWYAGSFEYDAIFRAIYTGDLPPYMITITAILIFIGAMGKSGQFPLHTWLPDAMEGPTPVSALIHAATMVAAGVYLVATMFPLFSASTVAMQTVAIVGAFTAIFAASIGLVQTDIKRVLAYSTVSQLGYMMLALGSAGYVAGIFHLTTHAFFKALLFLAAGSVIHAVHTQNINKMGGLQKKMKVTGTLFLIGTLAISGVPLLSGFFSKDEILAATWMNGNYVLFTLAVIAAFLTAFYMFRLYFLVFTGETKTKEEVHESPRVMTYPMIVLGVLAVVAGYINTPWFGTFLGDWLTKDVGFKVEETHGPVWIMIVATLVSFAGIALAYFIYSKKSISRNWAGGTETSLYNLLKEKYYVDELYNMTVIPITKGIAHVLRLFEVYVVEGIAVLIASVVKGTSNLGSKLQNGNVQVYGTVTAVSLAVLVIILLYTGGDLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017234_1	1.4\|3243723\|25\|NZ_CP017234\|CRT	3243723-3243747	25	MN013089	Bacillus phage vB_BspM_MarvelLand, complete genome	71238-71262	4	0.84
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	KY083059	Mycobacterium phage Achebe, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	KX550442	Mycobacterium phage Badger, complete genome	2187-2220	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	MN284905	Mycobacterium phage AbbysRanger, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	MK359322	Mycobacterium phage Datway, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	MK359310	Mycobacterium phage Katalie136, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	MK279898	Mycobacterium phage Cici, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	MK875799	Mycobacterium phage Xena, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	MK494115	Mycobacterium phage Bumblebee11, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	NC_042308	Mycobacterium virus Backyardigan, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	MF668278	Mycobacterium phage Morpher26, complete genome	2186-2219	7	0.794
NZ_CP017234_1	1.5\|3243768\|34\|NZ_CP017234\|CRT	3243768-3243801	34	NC_023709	Mycobacterium phage Wile, complete genome	2187-2220	7	0.794
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	KX156762	Staphylococcus phage vB_SauS_IMEP5, complete genome	19126-19159	7	0.794
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	NC_014792	Enterobacteria phage vB_EcoM-VR7, complete genome	108556-108589	8	0.765
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	KP007359	Enterobacteria phage vB_EcoM_VR5, complete genome	108402-108435	8	0.765
NZ_CP017234_3	3.1\|5140962\|31\|NZ_CP017234\|CRISPRCasFinder	5140962-5140992	31	JX238501	Bacillus phage phiAGATE, complete genome	124559-124589	8	0.742
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	KY705256	Streptococcus phage P3681, complete genome	18361-18394	9	0.735
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	MH937489	Streptococcus phage CHPC1034, partial genome	17131-17164	9	0.735
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	MH937492	Streptococcus phage CHPC1040, complete genome	16806-16839	9	0.735
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	MH937487	Streptococcus phage CHPC1029, complete genome	16818-16851	9	0.735
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	KY705257	Streptococcus phage P3684, complete genome	17220-17253	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	9	0.735
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	9	0.735
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	JN700521	Staphylococcus phage StB20, complete genome	36440-36473	10	0.706
NZ_CP017234_1	1.6\|3243822\|34\|NZ_CP017234\|CRT	3243822-3243855	34	NZ_CP015630	Borrelia turicatae strain BTE5EL plasmid lp159	39185-39218	10	0.706
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47181-47214	11	0.676
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47565-47598	11	0.676
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47949-47982	11	0.676
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48333-48366	11	0.676
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48717-48750	11	0.676
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49101-49134	11	0.676
NZ_CP017234_3	3.2\|5141016\|34\|NZ_CP017234\|CRISPRCasFinder	5141016-5141049	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49485-49518	11	0.676

1. spacer 1.4|3243723|25|NZ_CP017234|CRT matches to MN013089 (Bacillus phage vB_BspM_MarvelLand, complete genome) position: , mismatch: 4, identity: 0.84

gattggcccctgtgccccttgcact	CRISPR spacer
tattggttcctgtgccccttgcacc	Protospacer
 *****..****************.

2. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to KY083059 (Mycobacterium phage Achebe, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

3. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to KX550442 (Mycobacterium phage Badger, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

4. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to MN284905 (Mycobacterium phage AbbysRanger, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

5. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to MK359322 (Mycobacterium phage Datway, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

6. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to MK359310 (Mycobacterium phage Katalie136, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

7. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to MK279898 (Mycobacterium phage Cici, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

8. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to MK875799 (Mycobacterium phage Xena, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

9. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to MK494115 (Mycobacterium phage Bumblebee11, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

10. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to NC_042308 (Mycobacterium virus Backyardigan, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

11. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to MF668278 (Mycobacterium phage Morpher26, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

12. spacer 1.5|3243768|34|NZ_CP017234|CRT matches to NC_023709 (Mycobacterium phage Wile, complete genome) position: , mismatch: 7, identity: 0.794

ggttgctcctaccggtccctggattccttgtaga	CRISPR spacer
cttggctcctaccggaccctggataccttgctga	Protospacer
  * *********** ******** *****. **

13. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to KX156762 (Staphylococcus phage vB_SauS_IMEP5, complete genome) position: , mismatch: 7, identity: 0.794

ggttactccttgtatcccttgtggaccttgaatg	CRISPR spacer
tctttctccttgtataccttgtggaccttgtaaa	Protospacer
  ** ********** ************** * .

14. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to NC_014792 (Enterobacteria phage vB_EcoM-VR7, complete genome) position: , mismatch: 8, identity: 0.765

ggttactccttgtatcccttgtggaccttgaatg	CRISPR spacer
tttaggtccttgaataccttgtggaccttgaata	Protospacer
  * . ****** ** *****************.

15. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to KP007359 (Enterobacteria phage vB_EcoM_VR5, complete genome) position: , mismatch: 8, identity: 0.765

ggttactccttgtatcccttgtggaccttgaatg	CRISPR spacer
tttaggtccttgaataccttgtggaccttgaata	Protospacer
  * . ****** ** *****************.

16. spacer 3.1|5140962|31|NZ_CP017234|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

ttcttcttttttgtcactagttgaaccgctt	CRISPR spacer
ctaaccttttttgccactagttaaaccgccc	Protospacer
.*  .********.********.******..

17. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to KY705256 (Streptococcus phage P3681, complete genome) position: , mismatch: 9, identity: 0.735

ggttac--tccttgtatcccttgtggaccttgaatg	CRISPR spacer
--ttgcggtccttgaataccttgtggaccttggtca	Protospacer
  **.*  ****** ** **************. ..

18. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to MH937489 (Streptococcus phage CHPC1034, partial genome) position: , mismatch: 9, identity: 0.735

ggttac--tccttgtatcccttgtggaccttgaatg	CRISPR spacer
--ttgcggtccttgaataccttgtggaccttggtca	Protospacer
  **.*  ****** ** **************. ..

19. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to MH937492 (Streptococcus phage CHPC1040, complete genome) position: , mismatch: 9, identity: 0.735

ggttac--tccttgtatcccttgtggaccttgaatg	CRISPR spacer
--ttgcggtccttgaataccttgtggaccttggtca	Protospacer
  **.*  ****** ** **************. ..

20. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to MH937487 (Streptococcus phage CHPC1029, complete genome) position: , mismatch: 9, identity: 0.735

ggttac--tccttgtatcccttgtggaccttgaatg	CRISPR spacer
--ttgcggtccttgaataccttgtggaccttggtca	Protospacer
  **.*  ****** ** **************. ..

21. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to KY705257 (Streptococcus phage P3684, complete genome) position: , mismatch: 9, identity: 0.735

ggttac--tccttgtatcccttgtggaccttgaatg	CRISPR spacer
--ttgcggtccttgaataccttgtggaccttggtca	Protospacer
  **.*  ****** ** **************. ..

22. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

23. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

24. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

25. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

26. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

27. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

28. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

29. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

30. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

31. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

32. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

33. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

34. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

35. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

36. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

37. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

38. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to JN700521 (Staphylococcus phage StB20, complete genome) position: , mismatch: 10, identity: 0.706

ggttactccttgtatcccttgtggaccttgaatg	CRISPR spacer
ttgttctccttgcaacccttgtggaccttgttct	Protospacer
   * *******.* ***************  .

39. spacer 1.6|3243822|34|NZ_CP017234|CRT matches to NZ_CP015630 (Borrelia turicatae strain BTE5EL plasmid lp159) position: , mismatch: 10, identity: 0.706

ggttactccttgtatcccttgtggaccttgaatg	CRISPR spacer
tgctggtccgtgtatcccttgtgggccttgtgga	Protospacer
 *.*. *** **************.***** . .

40. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

41. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

42. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

43. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

44. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

45. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

46. spacer 3.2|5141016|34|NZ_CP017234|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

258303 : 266251

uncultured_virus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000917311.1\|258303_258588_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8
WP_044307015.1\|258626_260261_+	chaperonin GroEL	A0A219YK78	uncultured_virus	2.6e-157	58.0
WP_162837404.1\|260664_262206_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	8.9e-22	31.7
WP_000833082.1\|262590_263916_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	6.4e-45	30.1
WP_000929885.1\|264060_264762_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.3e-40	36.9
WP_088867628.1\|264745_266251_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	7.1e-32	30.3

DBSCAN-SWA_2

311823 : 320199

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625682.1\|311823_313131_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.3
WP_001170544.1\|313219_313939_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000278823.1\|313931_314186_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666774.1\|314182_314866_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000055562.1\|314849_317069_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.6e-163	41.2
WP_000879035.1\|317053_318469_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.6e-54	35.2
WP_001262439.1\|318574_319615_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.9
WP_000088589.1\|319611_320199_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.1e-28	37.4

DBSCAN-SWA_3

652987 : 661150

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_139124034.1\|652987_653983_-	WYL domain-containing protein	A0A1B0RXM1	Streptococcus_phage	1.1e-17	29.9
WP_000085783.1\|654047_654569_+	dihydrofolate reductase	NA	NA	NA	NA
WP_006918010.1\|654733_656125_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.1e-31	29.2
WP_006918011.1\|656136_656814_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-32	35.6
WP_000738879.1\|656989_658237_+	hypothetical protein	NA	NA	NA	NA
WP_000277056.1\|658370_658901_+	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	2.5e-16	34.3
WP_025710086.1\|658913_659258_+	DUF4064 domain-containing protein	A0A0S2MVJ2	Bacillus_phage	4.2e-41	77.2
WP_025710085.1\|659698_661150_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	9.8e-140	54.0

DBSCAN-SWA_4

1891512 : 1899609

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006929130.1\|1891512_1892802_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.3e-13	32.3
WP_001194314.1\|1892901_1893666_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_016122339.1\|1893906_1895667_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.1e-273	98.0
WP_000612413.1\|1895752_1896430_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-122	98.7
WP_001231629.1\|1896426_1897500_+	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	1.4e-186	97.8
WP_000818985.1\|1897727_1898447_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_001258539.1\|1898736_1899609_+	aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	2.8e-65	44.4

DBSCAN-SWA_5

2510279 : 2582019

Bacillus_phage(72.09%)

tail,head,terminase,protease,bacteriocin,holin,integrase,capsid,portal

attL 2515222:2515238|attR 2584689:2584705

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001071364.1\|2510279_2510600_+\|bacteriocin	heterocycloanthracin/sonorensin family bacteriocin	NA	NA	NA	NA
WP_002024190.1\|2511089_2511575_+	hypothetical protein	NA	NA	NA	NA
WP_088867749.1\|2511886_2512588_+	DUF3962 domain-containing protein	NA	NA	NA	NA
WP_088867750.1\|2512626_2513736_-\|integrase	tyrosine-type recombinase/integrase	A0A0U3U8Y8	Bacillus_phage	2.2e-147	79.1
WP_088867751.1\|2513939_2514119_+	hypothetical protein	NA	NA	NA	NA
WP_088867752.1\|2514490_2515699_+	hypothetical protein	D2XQ10	Bacillus_virus	9.5e-80	44.7
2515222:2515238	attL	NA	NA	NA	NA
WP_000791664.1\|2515725_2515881_+	hypothetical protein	NA	NA	NA	NA
WP_000425256.1\|2516141_2516492_-	helix-turn-helix transcriptional regulator	A0A288WFW4	Bacillus_phage	7.4e-17	39.7
WP_088867753.1\|2516674_2516971_+	helix-turn-helix transcriptional regulator	A0A288WG89	Bacillus_phage	4.0e-08	45.1
WP_000522024.1\|2517186_2517453_+	helix-turn-helix domain-containing protein	A0A0U3ULL9	Bacillus_phage	1.6e-35	90.6
WP_000390298.1\|2517452_2517617_+	hypothetical protein	A0A0U3B230	Bacillus_phage	1.5e-20	90.7
WP_088867754.1\|2517646_2517823_+	hypothetical protein	A0A1B1P7U0	Bacillus_phage	9.1e-24	91.4
WP_088867755.1\|2517827_2518574_+	DnaD domain protein	A0A1B0T6C0	Bacillus_phage	1.9e-78	80.3
WP_088867756.1\|2518512_2519388_+	ATP-binding protein	Q2I8C8	Bacillus_phage	4.2e-61	45.5
WP_061132169.1\|2519404_2519608_+	hypothetical protein	NA	NA	NA	NA
WP_088867757.1\|2519604_2519829_-	hypothetical protein	NA	NA	NA	NA
WP_088867758.1\|2519909_2520104_+	hypothetical protein	A0A1B1P7U7	Bacillus_phage	5.3e-25	85.9
WP_086410650.1\|2520129_2520303_+	DUF3954 domain-containing protein	A0A1B1P7U5	Bacillus_phage	6.8e-24	93.0
WP_088867759.1\|2520317_2520572_+	hypothetical protein	A0A1B0T6B9	Bacillus_phage	8.8e-36	86.9
WP_157673958.1\|2520661_2520853_+	glyoxalase	A0A1B0T6B5	Bacillus_phage	1.6e-26	93.7
WP_088867761.1\|2520984_2521392_-	DUF4870 domain-containing protein	NA	NA	NA	NA
WP_088867762.1\|2521575_2521824_-	hypothetical protein	A0A288WFY7	Bacillus_phage	1.9e-35	93.9
WP_157673959.1\|2522524_2522737_+	hypothetical protein	NA	NA	NA	NA
WP_088867763.1\|2522915_2523266_+	hypothetical protein	A0A0K2CNV8	Brevibacillus_phage	2.0e-14	55.2
WP_088867764.1\|2523296_2523578_+	hypothetical protein	NA	NA	NA	NA
WP_088867765.1\|2524118_2524883_-	hypothetical protein	NA	NA	NA	NA
WP_088867766.1\|2525804_2526074_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_065704049.1\|2526190_2526388_+	hypothetical protein	NA	NA	NA	NA
WP_081306072.1\|2526504_2526675_+	hypothetical protein	A0A1B0T6D0	Bacillus_phage	6.7e-08	71.4
WP_016081851.1\|2526702_2527185_+	ArpU family phage transcriptional regulator	H0USV3	Bacillus_phage	2.5e-71	82.5
WP_001012135.1\|2527184_2527727_+\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	7.3e-88	91.1
WP_001170296.1\|2527941_2528892_+	nucleoside hydrolase	NA	NA	NA	NA
WP_157673960.1\|2529265_2529886_+	hypothetical protein	NA	NA	NA	NA
WP_088867769.1\|2531312_2531576_+	hydrolase	NA	NA	NA	NA
WP_088867770.1\|2531562_2531898_+	HNH endonuclease	D2XR61	Bacillus_phage	3.8e-55	94.6
WP_088867771.1\|2532020_2532332_+\|terminase	P27 family phage terminase small subunit	D2XR14	Bacillus_phage	1.0e-38	83.3
WP_088867772.1\|2532328_2533996_+\|terminase	terminase large subunit	D2XR15	Bacillus_phage	3.5e-306	91.7
WP_046946472.1\|2534004_2535150_+\|portal	phage portal protein	D2XR16	Bacillus_phage	1.2e-180	87.0
WP_086421921.1\|2535149_2535893_+\|protease	Clp protease ClpP	D2XR17	Bacillus_phage	1.9e-131	98.0
WP_088867773.1\|2535896_2537051_+\|capsid	phage major capsid protein	A0A2H4JHU0	uncultured_Caudovirales_phage	3.2e-202	92.2
WP_088867774.1\|2537056_2537350_+	hypothetical protein	D2XR19	Bacillus_phage	7.0e-45	91.8
WP_088867775.1\|2537351_2537705_+\|head	phage head closure protein	A0A2H4JGG7	uncultured_Caudovirales_phage	5.1e-58	94.8
WP_088867776.1\|2537706_2538051_+	HK97 gp10 family phage protein	D2XR21	Bacillus_phage	4.1e-52	92.9
WP_088867777.1\|2538047_2538377_+	hypothetical protein	A0A2H4JAG4	uncultured_Caudovirales_phage	8.7e-52	89.9
WP_088867778.1\|2538377_2538971_+\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	2.2e-93	84.1
WP_000415935.1\|2538977_2539334_+	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	5.7e-41	70.8
WP_088867779.1\|2539564_2540776_+	hypothetical protein	A0A2H4JAI2	uncultured_Caudovirales_phage	4.0e-187	85.6
WP_088867780.1\|2541030_2541288_+	hypothetical protein	D2XR26	Bacillus_phage	3.2e-33	82.1
WP_088867781.1\|2541511_2543701_+	hypothetical protein	A0A2H4JC82	uncultured_Caudovirales_phage	2.9e-42	64.7
WP_088867782.1\|2543742_2545200_+\|tail	phage tail family protein	A0A0A7AQV1	Bacillus_phage	3.4e-172	59.7
WP_088867783.1\|2545196_2549729_+\|tail	phage tail protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	48.1
WP_088867784.1\|2549740_2550121_+	hypothetical protein	A0A0S2MVE0	Bacillus_phage	3.1e-45	74.2
WP_088867785.1\|2550239_2551634_+	PQQ-like beta-propeller repeat protein	NA	NA	NA	NA
WP_088867786.1\|2551721_2552147_+\|holin	phage holin family protein	A0A0S2MVC4	Bacillus_phage	4.2e-67	90.8
WP_088867787.1\|2552146_2552953_+	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	2.8e-152	91.0
WP_088867788.1\|2553206_2554040_+	hypothetical protein	NA	NA	NA	NA
WP_088867789.1\|2554044_2555262_+	hypothetical protein	NA	NA	NA	NA
WP_116344820.1\|2555917_2557600_+	DUF3893 domain-containing protein	NA	NA	NA	NA
WP_044307542.1\|2557806_2558574_+	DUF3959 family protein	NA	NA	NA	NA
WP_000905571.1\|2558718_2559135_+	DUF3995 domain-containing protein	NA	NA	NA	NA
WP_000878369.1\|2559255_2559459_+	hypothetical protein	NA	NA	NA	NA
WP_000362067.1\|2559788_2560001_-	hypothetical protein	NA	NA	NA	NA
WP_025710280.1\|2560210_2561215_+	DUF1835 domain-containing protein	NA	NA	NA	NA
WP_000282680.1\|2561360_2561765_+	hypothetical protein	NA	NA	NA	NA
WP_046392757.1\|2561924_2563160_+	cytochrome P450	NA	NA	NA	NA
WP_000106383.1\|2563427_2564711_+	MFS transporter	NA	NA	NA	NA
WP_001069247.1\|2564700_2565333_+	Vat family streptogramin A O-acetyltransferase	A0A2R8FE91	Brazilian_cedratvirus	2.7e-25	43.1
WP_000046095.1\|2565403_2565559_+	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_000289121.1\|2565661_2566159_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_088867790.1\|2566299_2567514_+	cytochrome P450	NA	NA	NA	NA
WP_000954437.1\|2567622_2568201_+	cysteine dioxygenase family protein	NA	NA	NA	NA
WP_000766385.1\|2568376_2569228_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_157673961.1\|2569678_2571466_+	PAS domain-containing protein	NA	NA	NA	NA
WP_088867791.1\|2571700_2573827_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_088867792.1\|2573903_2574431_+	signal peptidase I	NA	NA	NA	NA
WP_000932145.1\|2574663_2575851_+	UDP-glucosyltransferase	A0A2H4ZK81	Cryptophlebia_leucotreta_granulosis_virus	8.9e-06	24.1
WP_000864400.1\|2575941_2576622_-	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_061112981.1\|2577031_2577580_+	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_063264111.1\|2577590_2579291_+	energy-coupling factor ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	2.3e-15	29.5
WP_048535402.1\|2579283_2580084_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000120182.1\|2580220_2580328_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_070180162.1\|2580428_2581688_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	7.0e-25	29.1
WP_071730388.1\|2581824_2582019_-\|integrase	tyrosine-type recombinase/integrase	A0A1B0T6A8	Bacillus_phage	2.6e-11	64.0
2584689:2584705	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3579642 : 3674677

111

Bacillus_phage(41.94%)

tail,head,terminase,tRNA,protease,bacteriocin,holin,integrase,capsid,portal

attL 3645580:3645594|attR 3675347:3675361

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000872365.1\|3579642_3580008_+\|holin	CidA/LrgA family holin-like protein	NA	NA	NA	NA
WP_000578954.1\|3580004_3580682_+	LrgB family protein	NA	NA	NA	NA
WP_000442982.1\|3580694_3581108_-	NUDIX hydrolase	NA	NA	NA	NA
WP_044306942.1\|3581250_3581457_+	DUF3903 domain-containing protein	NA	NA	NA	NA
WP_044306943.1\|3581818_3582574_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_000644411.1\|3582672_3582819_-	BC1881 family protein	NA	NA	NA	NA
WP_000943745.1\|3583058_3583607_-	hypothetical protein	NA	NA	NA	NA
WP_001110280.1\|3583630_3584650_-	NERD domain-containing protein	A0A1L2JY40	Aeribacillus_phage	1.8e-26	28.7
WP_044306944.1\|3584791_3585838_-	SH3 domain-containing protein	A0A1U9WQS3	Geobacillus_phage	6.8e-34	40.9
WP_006920020.1\|3585968_3587732_-	ABC transporter ATP-binding protein	A0A076FI99	Aureococcus_anophage	8.9e-26	26.2
WP_006920021.1\|3587731_3589483_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.5e-49	29.6
WP_001123317.1\|3589605_3589827_-	YneF family protein	NA	NA	NA	NA
WP_000860645.1\|3589905_3590346_-	sporulation inhibitor of replication protein SirA	NA	NA	NA	NA
WP_000019766.1\|3590502_3592503_-	transketolase	NA	NA	NA	NA
WP_000047893.1\|3592799_3593603_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_001000763.1\|3593602_3594397_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_088867846.1\|3594393_3595167_-	phosphonate ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	4.6e-11	32.1
WP_061113401.1\|3595250_3596189_-	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000437456.1\|3596374_3597958_+	5'-nucleotidase C-terminal domain-containing protein	NA	NA	NA	NA
WP_000607015.1\|3597997_3598237_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_000991469.1\|3598282_3598939_-	recombinase family protein	NA	NA	NA	NA
WP_000413738.1\|3599080_3599701_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	8.2e-19	62.2
WP_048536031.1\|3599791_3600595_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_000031383.1\|3600595_3601138_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_001102628.1\|3601130_3601454_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_000392444.1\|3601825_3602056_-\|bacteriocin	bacteriocin biosynthesis protein	A0A1B1P7Q9	Bacillus_phage	1.5e-23	73.7
WP_088867847.1\|3602117_3602960_-	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	4.7e-33	47.7
WP_033692154.1\|3603078_3604065_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.7e-34	43.9
WP_000464425.1\|3604303_3604690_-	DUF1492 domain-containing protein	A0A288WG73	Bacillus_phage	2.6e-47	71.4
WP_033696536.1\|3604808_3605675_-	DnaD domain protein	A0A2H4J394	uncultured_Caudovirales_phage	1.2e-95	63.0
WP_001189065.1\|3605827_3606022_-	hypothetical protein	A0A1C8E9A1	Bacillus_phage	1.7e-15	71.0
WP_006920058.1\|3606033_3606792_-	phage regulatory protein	A0A2H4JBC7	uncultured_Caudovirales_phage	3.2e-97	69.4
WP_000283431.1\|3606994_3607207_-	hypothetical protein	A6M975	Geobacillus_virus	1.6e-11	63.0
WP_033692152.1\|3607409_3608069_+	helix-turn-helix domain-containing protein	A0A2H4J441	uncultured_Caudovirales_phage	6.6e-35	41.0
WP_088867848.1\|3608751_3609474_-	hypothetical protein	NA	NA	NA	NA
WP_088867849.1\|3609487_3609943_-	protein-export chaperone SecB	NA	NA	NA	NA
WP_088867850.1\|3609939_3610647_-	hypothetical protein	A0A142F155	Bacillus_phage	1.1e-11	34.1
WP_088867851.1\|3610853_3611063_-	DNA-binding protein	A0A1Z1LZP5	Bacillus_phage	1.2e-17	69.6
WP_000383887.1\|3611298_3611451_-	hypothetical protein	NA	NA	NA	NA
WP_078400394.1\|3611610_3612279_+	hypothetical protein	NA	NA	NA	NA
WP_049106735.1\|3612545_3612878_+	hypothetical protein	A0A1B1P7R0	Bacillus_phage	3.1e-25	60.7
WP_033690498.1\|3613046_3613286_-	DNA-binding protein	A0A2H4JBQ8	uncultured_Caudovirales_phage	2.6e-34	97.5
WP_061186062.1\|3613551_3613722_-	hypothetical protein	A0A2H4J852	uncultured_Caudovirales_phage	2.4e-13	92.9
WP_088867852.1\|3613837_3614770_-	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	2.2e-156	84.2
WP_088065444.1\|3614769_3615195_-\|holin	phage holin family protein	A0A1B1P787	Bacillus_phage	6.3e-71	98.6
WP_088868006.1\|3615234_3617388_-\|tail	tail fiber domain-containing protein	A0A1Z1LZM3	Bacillus_phage	1.5e-147	43.9
WP_088867853.1\|3622340_3623813_-\|tail	phage tail family protein	D2XPZ5	Bacillus_virus	1.0e-216	71.3
WP_157673968.1\|3623854_3626236_-	hypothetical protein	D2XR26	Bacillus_phage	7.0e-10	68.0
WP_157673969.1\|3626501_3627749_-	hypothetical protein	A0A2H4JAI2	uncultured_Caudovirales_phage	4.0e-182	84.0
WP_000415944.1\|3627979_3628342_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	9.2e-47	74.8
WP_001293689.1\|3628346_3628940_-\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	3.1e-92	84.1
WP_088867856.1\|3628940_3629270_-	hypothetical protein	A0A2H4JAG4	uncultured_Caudovirales_phage	1.9e-46	83.5
WP_088867857.1\|3629266_3629623_-	HK97 gp10 family phage protein	D2XR21	Bacillus_phage	1.2e-30	60.3
WP_088867858.1\|3629615_3629915_-\|head	phage head closure protein	R9TPZ2	Paenibacillus_phage	2.2e-09	39.4
WP_000972420.1\|3629911_3630184_-	DNA-packaging protein	R9TMB7	Paenibacillus_phage	3.2e-20	56.2
WP_088867859.1\|3630186_3630477_-	hypothetical protein	A6XMJ7	Bacillus_virus	2.8e-06	36.6
WP_000854839.1\|3630513_3631677_-\|capsid	phage major capsid protein	H7BUQ0	unidentified_phage	1.4e-80	55.1
WP_001043897.1\|3631690_3632275_-\|head,protease	HK97 family phage prohead protease	A0A2I7SBY1	Paenibacillus_phage	1.0e-39	50.5
WP_049106711.1\|3632240_3633452_-\|portal	phage portal protein	J9QE83	Clostridium_phage	5.9e-138	59.6
WP_088867860.1\|3633467_3635156_-\|terminase	terminase large subunit	A0A290GJW3	Caldibacillus_phage	1.4e-251	72.9
WP_088867861.1\|3635152_3635524_-	hypothetical protein	A0A2H4JA84	uncultured_Caudovirales_phage	3.3e-15	50.0
WP_088867862.1\|3635691_3635988_-	HNH endonuclease	R9TNN2	Paenibacillus_phage	1.7e-27	59.4
WP_049106707.1\|3636320_3636482_+	hypothetical protein	NA	NA	NA	NA
WP_088867863.1\|3636753_3637176_+	type II toxin-antitoxin system HicB family antitoxin	A0A1L2JY34	Aeribacillus_phage	8.8e-41	59.1
WP_088867864.1\|3637264_3637690_-	hypothetical protein	NA	NA	NA	NA
WP_049106704.1\|3637789_3638068_-	helix-turn-helix domain-containing protein	A0A2H4JBQ8	uncultured_Caudovirales_phage	1.2e-09	42.5
WP_157673970.1\|3638636_3639413_-	hypothetical protein	NA	NA	NA	NA
WP_088867866.1\|3639527_3640511_-	HNH endonuclease	NA	NA	NA	NA
WP_088867867.1\|3640543_3640876_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_088867868.1\|3641016_3641661_+	HNH endonuclease	NA	NA	NA	NA
WP_088868007.1\|3641709_3642747_-	hypothetical protein	NA	NA	NA	NA
WP_088867869.1\|3642898_3644845_-	AAA family ATPase	NA	NA	NA	NA
WP_088867870.1\|3645001_3645505_-	sigma-70 family RNA polymerase sigma factor	A0A1L2JY33	Aeribacillus_phage	3.6e-57	65.3
3645580:3645594	attL	NA	NA	NA	NA
WP_088867871.1\|3646062_3646638_-	RNA helicase	NA	NA	NA	NA
WP_088867872.1\|3646658_3649289_-	acyltransferase	NA	NA	NA	NA
WP_088867873.1\|3649643_3649892_-	hypothetical protein	NA	NA	NA	NA
WP_088867874.1\|3649948_3650491_-	hypothetical protein	NA	NA	NA	NA
WP_088867875.1\|3650572_3650947_-	ArpU family transcriptional regulator	A0A0M4R397	Bacillus_phage	1.4e-42	68.5
WP_000520472.1\|3650951_3651239_-	hypothetical protein	A6M999	Geobacillus_virus	1.9e-34	71.3
WP_071739277.1\|3651271_3651691_-	DNA cytosine methyltransferase	A0A1S5SFL7	Streptococcus_phage	3.1e-30	62.3
WP_088867876.1\|3651644_3652187_-	DNA (cytosine-5-)-methyltransferase	A0A0A8WFL3	Clostridium_phage	1.5e-56	57.9
WP_157673971.1\|3652244_3652991_-	FAD-dependent thymidylate synthase	A0A2P1JUN2	Bacillus_phage	2.2e-79	62.5
WP_044810252.1\|3653029_3653602_-	dUTP diphosphatase	A0A0A7AQI4	Bacillus_phage	2.6e-80	73.8
WP_000553935.1\|3653696_3653819_-	Fur-regulated basic protein FbpA	NA	NA	NA	NA
WP_088867877.1\|3653821_3654451_-	hypothetical protein	A0A0M4RU33	Bacillus_phage	1.7e-27	41.4
WP_088867878.1\|3654447_3654618_-	hypothetical protein	NA	NA	NA	NA
WP_088867879.1\|3654635_3655466_-	ATP-binding protein	U5PWH5	Bacillus_phage	1.2e-36	38.7
WP_088867880.1\|3655401_3656160_-	conserved phage C-terminal domain-containing protein	A0A1W6JNI1	Staphylococcus_phage	2.8e-61	54.9
WP_000849731.1\|3656156_3656429_-	hypothetical protein	A0A0M4S680	Bacillus_phage	8.5e-37	79.8
WP_088867881.1\|3656442_3657114_-	DUF1071 domain-containing protein	A0A1B1P7F0	Bacillus_phage	4.7e-28	45.5
WP_088867882.1\|3657110_3657593_-	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	6.3e-35	49.4
WP_000393080.1\|3657607_3657772_-	hypothetical protein	A0A0M5M3T1	Bacillus_phage	1.3e-11	64.8
WP_071739271.1\|3657843_3658161_-	hypothetical protein	NA	NA	NA	NA
WP_000483547.1\|3658311_3658578_-	hypothetical protein	S5MC08	Brevibacillus_phage	6.6e-26	57.0
WP_000139231.1\|3658682_3659411_-	Rha family transcriptional regulator	A0A288WFT2	Bacillus_phage	2.1e-50	49.1
WP_000877761.1\|3659407_3659608_-	helix-turn-helix transcriptional regulator	A0A0C5AJQ3	Paenibacillus_phage	1.9e-09	50.9
WP_078206691.1\|3659881_3660295_+	helix-turn-helix transcriptional regulator	A0A0M4QX29	Bacillus_phage	3.9e-25	47.1
WP_000673780.1\|3660317_3660746_+	ImmA/IrrE family metallo-endopeptidase	Q9T201	Bacillus_phage	6.2e-34	54.4
WP_000582647.1\|3660762_3660930_+	hypothetical protein	NA	NA	NA	NA
WP_000135916.1\|3660971_3662117_+\|integrase	site-specific integrase	A0A0M5M609	Bacillus_phage	3.3e-66	38.2
WP_000092763.1\|3662231_3663566_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_000656783.1\|3663614_3664004_-	transcriptional repressor GlnR	NA	NA	NA	NA
WP_000460304.1\|3664188_3665460_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000391407.1\|3665452_3666727_-	GTPase HflX	NA	NA	NA	NA
WP_000312266.1\|3666819_3667443_+	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_000181503.1\|3667542_3667680_+	hypothetical protein	NA	NA	NA	NA
WP_000438174.1\|3667711_3668668_-	stage V sporulation protein K	G3MAX6	Bacillus_virus	7.1e-54	42.6
WP_000450326.1\|3668781_3669747_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_088867883.1\|3669860_3673397_+	Gly-Xaa-Xaa repeat protein	NA	NA	NA	NA
WP_000813896.1\|3673477_3673702_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_006922262.1\|3673723_3674677_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
3675347:3675361	attR	NA	NA	NA	NA

DBSCAN-SWA_7

4449745 : 4457431

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221064.1\|4449745_4450669_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.0e-46	44.0
WP_000247679.1\|4450794_4451730_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.1e-22	25.3
WP_000018029.1\|4451731_4452424_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_001293578.1\|4452592_4452766_+	hypothetical protein	NA	NA	NA	NA
WP_001014310.1\|4452766_4452961_+	YwbE family protein	NA	NA	NA	NA
WP_001255971.1\|4452999_4454199_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.6e-71	41.2
WP_000587820.1\|4454494_4454818_+	heme oxygenase	NA	NA	NA	NA
WP_001086122.1\|4454890_4455655_-	class B sortase	NA	NA	NA	NA
WP_044306745.1\|4455687_4456458_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.6e-14	27.9
WP_001036848.1\|4456447_4457431_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	27.2

DBSCAN-SWA_8

4837973 : 4880365

Prochlorococcus_phage(14.29%)

protease,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_070180637.1\|4837973_4838651_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_006918873.1\|4838748_4839543_-	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_000248588.1\|4839594_4839903_-	YuzD family protein	NA	NA	NA	NA
WP_000431159.1\|4840098_4840335_+	NifU family protein	Q58MC7	Prochlorococcus_phage	2.0e-10	46.6
WP_001125507.1\|4840531_4840747_+	hypothetical protein	NA	NA	NA	NA
WP_000614215.1\|4840808_4841810_-\|coat	spore coat protein CotS	NA	NA	NA	NA
WP_000665103.1\|4841930_4842422_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	3.5e-41	53.8
WP_000351151.1\|4842445_4842925_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_049107541.1\|4843086_4844190_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_000856301.1\|4844134_4845481_+	phosphoribosyltransferase domain-containing protein	NA	NA	NA	NA
WP_088867964.1\|4845486_4846599_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	5.2e-40	31.7
WP_025709845.1\|4846595_4847411_+	HAD hydrolase family protein	NA	NA	NA	NA
WP_000683439.1\|4847966_4848548_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_069604583.1\|4848693_4849458_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_048534639.1\|4849567_4850200_-	transcriptional regulator	NA	NA	NA	NA
WP_000274006.1\|4850280_4850721_-	DUF86 domain-containing protein	NA	NA	NA	NA
WP_088867965.1\|4850868_4851840_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000392613.1\|4851856_4852123_+	DUF3055 domain-containing protein	NA	NA	NA	NA
WP_001174580.1\|4852494_4852992_+	hypothetical protein	NA	NA	NA	NA
WP_006918856.1\|4853003_4853525_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000435943.1\|4853535_4853838_-	DUF1027 domain-containing protein	NA	NA	NA	NA
WP_000744132.1\|4853956_4854535_+	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_000178775.1\|4854569_4855304_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_002164635.1\|4855404_4856220_+\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_000738181.1\|4856250_4856685_-	hypothetical protein	NA	NA	NA	NA
WP_000721022.1\|4856818_4857373_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_000272746.1\|4857447_4857927_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_000166372.1\|4857948_4858845_-	lipoyl synthase	NA	NA	NA	NA
WP_000944665.1\|4859034_4860018_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_012593364.1\|4860091_4860823_-	sporulation protein YunB	NA	NA	NA	NA
WP_000248466.1\|4860877_4861180_-	DUF1805 domain-containing protein	NA	NA	NA	NA
WP_080348338.1\|4861245_4862637_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_001118827.1\|4863356_4864754_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_000009523.1\|4864802_4865234_-	iron-sulfur cluster assembly scaffold protein SufU	A0A0K1LS29	Mycobacterium_phage	1.5e-14	37.6
WP_001020767.1\|4865223_4866444_-	cysteine desulfurase SufS	Q2XUY6	environmental_halophage	2.3e-118	47.6
WP_000152167.1\|4866443_4867736_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000929160.1\|4867751_4868537_-	Fe-S cluster assembly ATPase SufC	A0A285PWH2	Cedratvirus	1.3e-08	25.8
WP_000757014.1\|4868775_4869582_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000735102.1\|4869653_4870466_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000359557.1\|4870489_4871155_-	ABC transporter permease	NA	NA	NA	NA
WP_000601790.1\|4871147_4872173_-	methionine ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_001242138.1\|4872715_4873060_-	hypothetical protein	NA	NA	NA	NA
WP_002025020.1\|4873212_4873521_-	thioredoxin family protein	NA	NA	NA	NA
WP_000640870.1\|4873524_4873869_-	hypothetical protein	NA	NA	NA	NA
WP_000026897.1\|4874245_4874629_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_000218968.1\|4874670_4875036_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.1e-21	48.6
WP_000826874.1\|4875446_4875974_-	hypothetical protein	NA	NA	NA	NA
WP_000713775.1\|4876117_4876765_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000666171.1\|4876828_4877842_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_135811602.1\|4877864_4879064_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_001002981.1\|4879060_4879309_-\|coat	spore coat protein	NA	NA	NA	NA
WP_001180555.1\|4879322_4879508_-	hypothetical protein	NA	NA	NA	NA
WP_001232990.1\|4879651_4880365_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP017234

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection