CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP016360	Bacillus cereus strain M13 chromosome, complete genome	3 crisprs	cas3,csa3,WYL,DinG,RT,cas14k,Cas14u_CAS-V,c2c9_V-U4,DEDDh,cas14j	4	8
NZ_CP016363	Bacillus cereus strain M13 plasmid pBCM1303, complete sequence	0 crisprs	NA	0	0
NZ_CP016361	Bacillus cereus strain M13 plasmid pBCM1301, complete sequence	0 crisprs	NA	0	0
NZ_CP016362	Bacillus cereus strain M13 plasmid pBCM1302, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016360_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016360_1

1061639-1061767

Orphan

Consensus_repeat	Method
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP016360_1

>merge|NZ_CP016360|1|1061639-1061767|CRISPRCasFinder
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGGTTCAAGCCAAGTAACAGATGGTTTAGGAACATTATCTGTAGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG

>NZ_CP016360|1|1|1061639-1061767|CRISPRCasFinder
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG	TTCAAGCCAAGTAACAGATGGTTTAGGAACATTATCTGT
AGGAGCAAACCAAATGGCAGGTGGCGTAAATCAATTAGCAGATGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016360.1\|WP_000184504.1\|1056293_1056695_+\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NZ_CP016360.1\|WP_000567010.1\|1065586_1065715_-\|YhfH-family-protein	unknown	unknown	gnl\|CDD\|379490
NZ_CP016360.1\|WP_033684308.1\|1047276_1048323_+\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NZ_CP016360.1\|WP_001176850.1\|1054864_1055164_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_000972006.1\|1055218_1056064_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_000963381.1\|1058824_1059397_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP016360.1\|WP_000897277.1\|1066639_1067629_+\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
NZ_CP016360.1\|WP_000784676.1\|1065895_1066630_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293802
NZ_CP016360.1\|WP_000832612.1\|1067768_1068197_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_000726775.1\|1048337_1049273_+\|ferrochelatase	unknown	unknown	gnl\|CDD\|183526
NZ_CP016360.1\|WP_001055146.1\|1068358_1069891_+\|fatty-acid--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|236072
NZ_CP016360.1\|WP_001228071.1\|1049292_1050714_+\|protoporphyrinogen-oxidase	unknown	unknown	gnl\|CDD\|237009
NZ_CP016360.1\|WP_073339313.1\|1050770_1052123_-\|DUF4026-domain-containing-protein	unknown	unknown	gnl\|CDD\|338635
NZ_CP016360.1\|WP_001986098.1\|1062793_1063006_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_000279275.1\|1052364_1054731_+\|endonuclease	unknown	unknown	gnl\|CDD\|225249
NZ_CP016360.1\|WP_001068218.1\|1063342_1063696_-\|PlcR-regulated-protein-PRP2	unknown	unknown	gnl\|CDD\|379617
NZ_CP016360.1\|WP_000140291.1\|1063010_1063316_+\|DUF2087-domain-containing-protein	unknown	unknown	gnl\|CDD\|226378
NZ_CP016360.1\|WP_033684311.1\|1056697_1058611_+\|M56-family-metallopeptidase	unknown	unknown	gnl\|CDD\|310280
NZ_CP016360.1\|WP_000620467.1\|1063829_1064339_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP016360.1\|WP_000103715.1\|1064533_1065547_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525

Protein	Function_ID	Function_description	E-value
NZ_CP016360.1\|WP_000279275.1\|1052364_1054731_+\|endonuclease	gnl\|CDD\|225249	COG2374, COG2374, Predicted extracellular nuclease [General function prediction only].	9.41892e-72
NZ_CP016360.1\|WP_000567010.1\|1065586_1065715_-\|YhfH-family-protein	gnl\|CDD\|379490	pfam14149, YhfH, YhfH-like protein. The YhfH-like protein family includes the B. subtilis YhfH protein, which is functionally uncharacterized. Its expression is repressed by the Spx paralogue MgsR, which regulates genes involved in stress response. This family of proteins is found in bacteria. Proteins in this family are typically between 42 and 53 amino acids in length.	3.52581e-13
NZ_CP016360.1\|WP_033684308.1\|1047276_1048323_+\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_CP016360.1\|WP_000963381.1\|1058824_1059397_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.571e-14
NZ_CP016360.1\|WP_000897277.1\|1066639_1067629_+\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	2.90203e-139
NZ_CP016360.1\|WP_001228071.1\|1049292_1050714_+\|protoporphyrinogen-oxidase	gnl\|CDD\|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	0
NZ_CP016360.1\|WP_000726775.1\|1048337_1049273_+\|ferrochelatase	gnl\|CDD\|183526	PRK12435, PRK12435, ferrochelatase; Provisional.	0
NZ_CP016360.1\|WP_000184504.1\|1056293_1056695_+\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	6.62394e-45
NZ_CP016360.1\|WP_000140291.1\|1063010_1063316_+\|DUF2087-domain-containing-protein	gnl\|CDD\|226378	COG3860, COG3860, Uncharacterized protein conserved in bacteria [Function unknown].	4.70267e-24
NZ_CP016360.1\|WP_073339313.1\|1050770_1052123_-\|DUF4026-domain-containing-protein	gnl\|CDD\|338635	pfam13218, DUF4026, Protein of unknown function (DUF4026). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 450 amino acids in length. The family is found in association with pfam10077.	4.31509e-176
NZ_CP016360.1\|WP_001055146.1\|1068358_1069891_+\|fatty-acid--CoA-ligase-family-protein	gnl\|CDD\|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP016360.1\|WP_000103715.1\|1064533_1065547_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.56346e-114
NZ_CP016360.1\|WP_000784676.1\|1065895_1066630_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	9.0311e-87
NZ_CP016360.1\|WP_001068218.1\|1063342_1063696_-\|PlcR-regulated-protein-PRP2	gnl\|CDD\|379617	pfam14470, bPH_3, Bacterial PH domain. Proteins in this family are distantly related to PH domains.	9.48462e-20
NZ_CP016360.1\|WP_033684311.1\|1056697_1058611_+\|M56-family-metallopeptidase	gnl\|CDD\|310280	pfam05569, Peptidase_M56, BlaR1 peptidase M56. Production of beta-Lactamase and penicillin-binding protein 2a (which mediate staphylococcal resistance to beta-lactam antibiotics) is regulated by a signal-transducing integral membrane protein and a transcriptional repressor. The signal transducer is a fusion protein with penicillin-binding and zinc metalloprotease domains. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. homologs to this peptidase domain, which corresponds to Merops family M56, are also found in a number of other bacterial genome sequences.	3.49991e-47
NZ_CP016360.1\|WP_000620467.1\|1063829_1064339_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.55712e-15

>NZ_CP016360.1|WP_000963381.1|1058824_1059397_+|TetR/AcrR-family-transcriptional-regulator
MAIDRKRSIIEAATKSFSAFGYKATTMDQVAKLANVGKGTIYTFFKNKEELFGEIISNLITEMKQVAESAIRSDVSFFENVHRALYSILEFRKEHQLMIKLIQEERDMGTKEVQEVMQQVDVEIVSVIQSYLKIAIEKGEISKCDPEITAFIMLRLYVSLIFDWEKNHEPLEKEKIAELFELYLLKGLSN
>NZ_CP016360.1|WP_033684311.1|1056697_1058611_+|M56-family-metallopeptidase
MINTLINVYLPHFFDWLIETSLMASILVGFILCIKVLFRNKLTPRWQYMLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPATENIVNIESDRKVELESNSKMVTKTSEPEVKVSSEKQTTFSLYKLALYVWLAGVIIVAAITFLTNRRLYSYIKKQPDITDEQVTTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNEQQLQYVFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEEQIAYGHTIITLLQHYSYQVPSLANLSRNKRTLKRRIVMIKKFQKKSYRLSLLGIIAIVAIASLSLFNARTTEGKEKQEDKVEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFLYHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQGDIKEVKEERLSTENREKLKEIRNKTTPYEDKVGKYLTYTVEEVQQHVDFQIKRPTYTIKGYTQKDERVNYYLKIKPEFTIELEYTNGKGNYTISQSQVFGESKDPFSHQFVVPENIEQYELEGNQIFYATHHSDSNLQGMKMIVPAKGKNSAYQIVIINHSLENQGEAVFDKNVNKEELEKIMLSMLK
>NZ_CP016360.1|WP_000184504.1|1056293_1056695_+|BlaI/MecI/CopY-family-transcriptional-regulator
MTNQLPKISEAELEIMKVLWSNSPQTANEIIEELEDAMDWKPKTIRTLINRLVQKEAVSYHQDKGRMYAYYPLVSQHNYLQVETKSLLKRFCGAAFKPLLVNFLKEEKLSSEDINELKRILDEKTEENKRKDR
>NZ_CP016360.1|WP_000972006.1|1055218_1056064_-|hypothetical-protein
MMHALRLNIKQAFCNRVSLIIMFSGFVLICIYHYYYVIRYLGDAANGPISTDIKWIGFRGNEMDVYLLLMPVIASLPFSTSYNSDKSDGFKPFVSKEISLFSYSVTKYIVTFFCGGLLYTFPFILSLLFCKLTIPDGVPTAGSGIINDNGMFANLYETSPITYIAVYIGINFLFAGLMALLGLAASAWSQKDYMALLFPFATTSIPYVLLNTVLPTIGGAPIHLYDPRQPLHGMSPYILTIQCAFFLLVSLIMYIQGVKRDRKKYRRRLQKRERCRKAFQV
>NZ_CP016360.1|WP_001176850.1|1054864_1055164_+|hypothetical-protein
MQLQINGKVMNQFAIFFSTIVMLQFVADITGLTSNLDITYNLIHTATSYITFSLAVIFTLIGARRELSKYAIVSLCLVIAIKAIYFVAVVILWGLAGTP
>NZ_CP016360.1|WP_000279275.1|1052364_1054731_+|endonuclease
MAVKKLLSVFLSFLLLLSFTGTLAQAEETASMSVEKAIQVFKQQGKTKGIVEGYIVGYTQSSSKYTKDPAKFDDTNVAIADSPNETNPDKIMPVQLPKGDVRTAVNVKDHPENIGKKVSLTGTLELYFSNPGLKSVTAYKFQGEGQNRVSDVVASPNGGEVAKGTAVTLTTNTEGATIYYTLDGSNPTNKSVLYNGQIIVNENSVVKAIAEKEGLTSSAISTFSFIIVNNEPVRIHDIQGKSHMSPYNGKKVNNVEGVVTALDKNGFYIEDNQPDNDPATSEGMYVYKKDANVAVGDLIQVDGVVEEYVGPGYAERFETDLTTTEIKASRVVVIAKDQSLPAPIVLGENGVKIPDQIIDNDAFGLFDPNEDAIDFYESIEGMRVTMPTPKVIAPQKNGNLYVTVKNGGDKIVTQYGTPLLDENQLNPERLSVKVPRDYVAKVGDTFTGDITGVVGYDYGSFRISPITELPAVVDGGFKQVGANIQPRLDKLTVATYNIENFSANKKETTDEKVKALAYSIKYNLKMPDIIGVEEMQDNNGSINDGTTDASLSAKRIIDAVLEIRGPKYEYVEIAPNNNQDGGAPGANIRVGFFYNPSRVKLAPVPKLLDKNVVRIGDENPLFESTRKPLAAEFTFQGQNIVVVANHLNSKLGDATPFGKVQPLVLKSEDKRIQLAQEVNHFVQGIQKKNTNAPVVVLGDMNDFEFSKPLKTLEGTILKDMLNTVPKENRYTYIHEGNAQVLDHILVTNNIAPHTIVDSVHLNSNIMKEHGRVSDHDPVLAQIDLKKAS
>NZ_CP016360.1|WP_073339313.1|1050770_1052123_-|DUF4026-domain-containing-protein
MEVQTETYRAAMNGTLERHFSDMIAVIPTRITIEQLKQRLENIATKVDELKIVYSDETSLIVELHMDETIIPYELHIDEANDPEEYKMYNRQDSTIVDRNFEYAAFGTEIFTRTLFVGDVLDCFFQQIQFLWNLAPDLLFVIDSSAAMKVISRNYIEYHVENELLPDIPDLYVIHSVYEDDKEGEPTQYWFHTHGLLRAGVTEIELIIPNRISSYYGIGDLFQTFANNAVENGQVPMNEPIVIAHSQQGSIHTVAVPWEKGLSYIGHKTSMDQLSSIEDEEVKLQPIDAQNTFLGGMDARDEYHQSPSVLLFKFNTSEEYIESFFKEHEEATGLMFYKTNSETDRMAYNAKNTFGYFSNIFQIEKSNEEFRFLAKFGVSYEEGKSEHMWFEMQHITEDLIQGILINEPYFIDDMSEGNSYHLDFDNLTDWVIYAGDAVIKPNNLYMFIGE
>NZ_CP016360.1|WP_001228071.1|1049292_1050714_+|protoporphyrinogen-oxidase
MRKKVVIIGGGITGLTAMYNLQKNIHEKNLPIDTLLIEASGKLGGKIQTVRKDGFTIERGPDSFLARKESAARLVKELGLGDELVNNQAGQSFILVNNRLHKMPNGSMMGIPTQITPFLFSGLFSPIGKLRAGFDLLMPRSKPVSDQSLGQFFRHRLGNEVVENLIEPLLSGIYAGDIDEMSLMSTFPQMYQIEQKHRSISLGMRTLAPKEEKAEPKKGMFQTVKTGLESIVKSLEAKMHEGTIIKGTRIEKVAKQGDGYTITLSNGKEIEADAIVVATSHKVLPSMFAQYKQFRFFRNIPSTSVANVALAFQKSAIQRDINGTGFVVSRNSDYTITACTWTHKKWPHTTPEGKTLLRCYVGRAGDEAVVEQTEEELVQLVLEDLRKTMDITEDPEFTIVSRWKEAMPQYTVGHNERMKKLTTFMEKELPGIYLAGSSYAGAGLPDCMNQGEEAAKRVLSHLEKVIDAELIAQ
>NZ_CP016360.1|WP_000726775.1|1048337_1049273_+|ferrochelatase
MKKKIGLLVMAYGTPYKEEDIERYYTHIRRGRKPSPEMLEDLTERYRAIGGISPLATITLEQAKKLEKRLNEVQDEVEYHMYLGLKHIEPFIEDAVKDMHNDGIQDAIALVLAPHYSTFSVKSYVGRAQEEAEKLGNLTIHGIDSWYKEPKFIQYWVDAVKGIYNGMSDAEREKAVLIVSAHSLPEKIIAMGDPYPDQLNETADYIARGAEVANYAVGWQSAGNTPDPWIGPDVQDLTRELNEKHGYTSFVYAPVGFVAEHLEVLYDNDFECKVVTDEIGAKYYRPEMPNASDAFIDCLTDVVLKKKESVL
>NZ_CP016360.1|WP_033684308.1|1047276_1048323_+|uroporphyrinogen-decarboxylase
MVRTINETFLKACRGERTDYVPAWYMRQAGRSQPEYRKIKEKYSLFEITHNPELCAYVTKLPVDQYNVDAAILYKDIMSPLPAIGVDVEIKSGIGPVIDNPIRSLQDVEKLGEINPEDDVPYILDTIRLLTTEMLDVPLIGFSGAPFTLASYMIEGGPSRNYHNTKAFMYAEPKAWFALMDKLADMVITYLKAQINAGAKAVQIFDSWVGTVNVADYRVFIKPAMERIFAEVRKMDVPMIMHGVGAAHLVNEWHDLPLDVVGLDWRLPIEEARARGVHKAVQGNMDPSFLLAPWSVIEEHVKSILDQGMKQPGYIFNLGHGVFPEVNPDTLKRLTTFIHEYSKGQLAK
>NZ_CP016360.1|WP_001986098.1|1062793_1063006_+|hypothetical-protein
MMKGNLTYYFIVNPLIIFLVYALSPILFDKEVYTSMKDAFGILTFYYVLMGGYYFIDILSEKIKKKSDGG
>NZ_CP016360.1|WP_000140291.1|1063010_1063316_+|DUF2087-domain-containing-protein
MTESEMKFRDTTIRNFFDKEDRLKSIPGQKKKKLVLLEHLISKLNAENQYTEKEINTFIKQYHDDFCTIRREFIVQGFMNREDNMYCINGREVWTKWEELK
>NZ_CP016360.1|WP_001068218.1|1063342_1063696_-|PlcR-regulated-protein-PRP2
MNPILTAAKQLLHKEEKILSTLKCSLTGYMITHKVPYPGMLLATNQRLLFFSQYKNTFIAEFDYEKILSIETKRRIFDKKIIFYYEDEHITLGYITSSNVEAFIDLLQRNSKTSTGL
>NZ_CP016360.1|WP_000620467.1|1063829_1064339_+|GNAT-family-N-acetyltransferase
MIRLVKETDAEAIMNIRKEIILSETTTKFFIVSPKKLPNDMNAEREKIRKSNEKGNLYIVYEVDGKVVGFLIFNRYELERLQHAGTMGMGIKEAYCNQGIGTKLIEFLISWAKGQKGLEKICLGVVSVNDRAIKVYKRMGFVEEGRQRKQIKYEDGSYGDDVLMGFYIE
>NZ_CP016360.1|WP_000103715.1|1064533_1065547_+|LacI-family-DNA-binding-transcriptional-regulator
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLDQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAILAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFELELLVKGSTMKDKMLLA
>NZ_CP016360.1|WP_000567010.1|1065586_1065715_-|YhfH-family-protein
MIDQPMEFFRNLPTKTCAHCGKEIDEQHEAYHNKCDDCVHEE
>NZ_CP016360.1|WP_000784676.1|1065895_1066630_+|MBL-fold-metallo-hydrolase
MKMTVVGFWGGFPEAGEATSGYLFEHDGFRLLVDCGSGVLAQLQKYITPSDIDAVVLSHYHHDHVADIGVLQYARLITSATTRQLPELPIYGHTFDENGFHSLTHEPHTKGIPYNPEETLQIGTFSISFLKTVHPVTCFAMRITAGNDIVVYSADSSYIPEFIPFTKDADLFICECNMYAHQEAAKAGHMNSTEVASIAKDANVKELLLTHLPHTGNPSDLVTEAKQIFSGHITLAHSGYVWNS
>NZ_CP016360.1|WP_000897277.1|1066639_1067629_+|lipoate--protein-ligase
MLFIDNKGITDPRINLAIEEYCVKNLDINETYLLFYINEPSIIIGKNQNTVEEINADYVKEKGIHVVRRLSGGGAVYHDLGNLNFSFITKDDGDSFSNFKKFTEPVTKALSKLGVNAELSGRNDILAEGRKISGNAQFATKGRMFSHGTLLFDSEIDHVVSALKVKMDKIQSKGIKSIRSRVANITEFLNEEMTTEEFRQLLLETIFEGETEIPTYELTENDWKEIHKLSEERYQNWDWNYGKSPKFNLQHSHRFPVGQVDVRLEVKKGTVTECKIYGDFFGSLDVHDIEERLTGVQFDKDAFTAALEGVDIARYFGNITTEDFLHLFF
>NZ_CP016360.1|WP_000832612.1|1067768_1068197_+|hypothetical-protein
MKRVMYVILLLSFVIGMTACNSGLPSSRTILSIGKPAEDNVIYFTHTDNKRKIHDIQDMFQNKKWKRNETFSTVNKTPDVVLSIDENNKGLPTLYVTVYFHEDGADALNLHGEHTTLNKEELNKLREKMNAYYPKMISGLVS
>NZ_CP016360.1|WP_001055146.1|1068358_1069891_+|fatty-acid--CoA-ligase-family-protein
MNLVQSLAETAKKKGDKPAYIFMDQSVSYDQLNKMVTRFSGNLAEMGIGKGDNVALVVGNSPHFLVGLYGTMKAGATVIPVNPIYTADEMHYILQNGDVKTIIVLDVLLPVIQSLTTRLPSLENIIICETSSDFNHTETEKMKTFTSFVGAGDTTYEGPELDEEDVAVILYTSGTTGKPKGAMLTHKNLYSNASDVASYLQYTADDRVVAALPMFHVFCLTVAVNAPIVNGATILMLPKFSPKEVFRICRTYEPTIFAGVPTMYNYLYLFEEASAEDVKTLRLCISGGASMPVALLQNFEKRFNVIVSEGYGLSEASPVTCFNPLDRPRKPGSIGTNIWHVENKIVNELGEEVPVGAVGELIVRGPNVMKGYYNAPEDTAATLKDGWLYTGDLAKMDEEGYFYIVDRKKDIVLVGGYNVYPREVEEVLYTHESVAEVVVIGVPDENLGEAVRAYVVLKQTNVTEEELMHYCTLHLAKYKVPKSIEFLIELPKNTTGKLLRRALREKAMQV

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Crispr_ID: NZ_CP016360_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016360_2

3654256-3654413

Orphan

Consensus_repeat	Method
CCCCTCATTAATAATGCCTTTAACTAAGGCACTTT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP016360_2

>merge|NZ_CP016360|2|3654256-3654413|CRISPRCasFinder
CCCCTCATTAATAAAGCCCCTAACTAGGATATTTTGTGACCATTTTACCTTTTTTAAAATACCCCTCATTAATAATGCCTTTAACTAAGGCACTTTGTACGTGTTTTGTATTTGAGAAATAATCCCCTCATTAATAATGCCTTTAACTAAGCACTTTT

>NZ_CP016360|2|2|3654256-3654413|CRISPRCasFinder
CCCCTCATTAATAAAGCCCCTAACTAGGATATTTT	GTGACCATTTTACCTTTTTTAAAATA
CCCCTCATTAATAATGCCTTTAACTAAGGCACTTT	GTACGTGTTTTGTATTTGAGAAATAAT
CCCCTCATTAATAATGCCTTTAACTAAGCACTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016360.1\|WP_073340322.1\|3646021_3647422_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|377466
NZ_CP016360.1\|WP_001123317.1\|3656318_3656540_-\|YneF-family-protein	unknown	unknown	gnl\|CDD\|100947
NZ_CP016360.1\|WP_000860636.1\|3656618_3657059_-\|sporulation-inhibitor-of-replication-protein-SirA	unknown	unknown	gnl\|CDD\|371220
NZ_CP016360.1\|WP_073340300.1\|3651168_3651375_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_000569240.1\|3661106_3661880_-\|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226164
NZ_CP016360.1\|WP_000437455.1\|3663087_3664671_+\|2',3'-cyclic-nucleotide-2'-phosphodiesterase	unknown	unknown	gnl\|CDD\|277355
NZ_CP016360.1\|WP_000607016.1\|3664710_3664950_-\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|100891
NZ_CP016360.1\|WP_073340305.1\|3650066_3651131_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_000019766.1\|3657215_3659216_-\|transketolase	unknown	unknown	gnl\|CDD\|223100
NZ_CP016360.1\|WP_073340296.1\|3651407_3652223_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_073340317.1\|3647470_3648034_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_073340309.1\|3649665_3650049_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_073340291.1\|3652420_3652594_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP016360.1\|WP_000047894.1\|3659512_3660316_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NZ_CP016360.1\|WP_073340285.1\|3652693_3653575_-\|DUF5309-domain-containing-protein	unknown	unknown	gnl\|CDD\|379950
NZ_CP016360.1\|WP_000915065.1\|3661963_3662902_-\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|225762
NZ_CP016360.1\|WP_073340281.1\|3653596_3654046_-\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|373570
NZ_CP016360.1\|WP_073340277.1\|3655212_3656127_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NZ_CP016360.1\|WP_001000763.1\|3660315_3661110_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NZ_CP016360.1\|WP_073340313.1\|3648088_3649666_-\|DNA-packaging-protein	unknown	unknown	gnl\|CDD\|222858

Protein	Function_ID	Function_description	E-value
NZ_CP016360.1\|WP_073340322.1\|3646021_3647422_-\|phage-portal-protein	gnl\|CDD\|377466	pfam05133, Phage_prot_Gp6, Phage portal protein, SPP1 Gp6-like. This protein forms a hole, or portal, that enables DNA passage during packaging and ejection. It also forms the junction between the phage head (capsid) and the tail proteins. During SPP1 morphogenesis, Gp6 participates in the procapsid assembly reaction. This family also includes the old Pfam family Phage_min_cap (PF05126).	2.66203e-54
NZ_CP016360.1\|WP_001123317.1\|3656318_3656540_-\|YneF-family-protein	gnl\|CDD\|100947	PRK01844, PRK01844, YneF family protein.	1.00023e-24
NZ_CP016360.1\|WP_000860636.1\|3656618_3657059_-\|sporulation-inhibitor-of-replication-protein-SirA	gnl\|CDD\|371220	pfam10747, SirA, Sporulation inhibitor of replication protein SirA. This entry represents the Sporulation inhibitor of replication (sirA) family of proteins from Bacillus sp. Induction of sporulation in rapidly growing cells inhibits replication; this is thought to be through the action of SirA protein and independent of phosphorylated Spo0A; however SirA protein synthesis is induced by Spo0A.	1.97274e-45
NZ_CP016360.1\|WP_000019766.1\|3657215_3659216_-\|transketolase	gnl\|CDD\|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NZ_CP016360.1\|WP_000569240.1\|3661106_3661880_-\|phosphonate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226164	COG3638, COG3638, ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism].	2.91148e-134
NZ_CP016360.1\|WP_000437455.1\|3663087_3664671_+\|2',3'-cyclic-nucleotide-2'-phosphodiesterase	gnl\|CDD\|277355	cd07410, MPP_CpdB_N, Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain. CpdB is a bacterial periplasmic protein with an N-terminal metallophosphatase domain and a C-terminal 3'-nucleotidase domain. This alignment model represents the N-terminal metallophosphatase domain, which has 2',3'-cyclic phosphodiesterase activity, hydrolyzing the 2',3'-cyclic phosphates of adenosine, guanosine, cytosine and uridine to yield nucleoside and phosphate. CpdB also hydrolyzes the chromogenic substrates p-nitrophenyl phosphate (PNPP), bis(PNPP) and p-nitrophenyl phosphorylcholine (NPPC). CpdB is thought to play a scavenging role during RNA hydrolysis by converting the non-transportable nucleotides produced by RNaseI to nucleosides which can easily enter a cell for use as a carbon source. This family also includes YfkN, a Bacillus subtilis nucleotide phosphoesterase with two copies of each of the metallophosphatase and 3'-nucleotidase domains. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.94794e-128
NZ_CP016360.1\|WP_000607016.1\|3664710_3664950_-\|DUF896-domain-containing-protein	gnl\|CDD\|100891	PRK01546, PRK01546, hypothetical protein; Provisional.	1.66541e-33
NZ_CP016360.1\|WP_000915065.1\|3661963_3662902_-\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|225762	COG3221, PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism].	2.81626e-88
NZ_CP016360.1\|WP_073340291.1\|3652420_3652594_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.19787e-07
NZ_CP016360.1\|WP_000047894.1\|3659512_3660316_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	8.79798e-96
NZ_CP016360.1\|WP_073340285.1\|3652693_3653575_-\|DUF5309-domain-containing-protein	gnl\|CDD\|379950	pfam17236, DUF5309, Family of unknown function (DUF5309). This is a family of uncharacterized proteins found in viruses and bacteria.	1.13647e-93
NZ_CP016360.1\|WP_073340281.1\|3653596_3654046_-\|xanthine-phosphoribosyltransferase	gnl\|CDD\|373570	pfam15112, DUF4559, Domain of unknown function (DUF4559). This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. This family includes human protein CXorf38.	0.00602011
NZ_CP016360.1\|WP_073340277.1\|3655212_3656127_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	4.47935e-53
NZ_CP016360.1\|WP_073340313.1\|3648088_3649666_-\|DNA-packaging-protein	gnl\|CDD\|222858	PHA02533, 17, large terminase protein; Provisional.	6.57754e-46
NZ_CP016360.1\|WP_001000763.1\|3660315_3661110_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	2.00572e-97

>NZ_CP016360.1|WP_073340281.1|3653596_3654046_-|xanthine-phosphoribosyltransferase
MQEINNQEQQEQTQGVEETQQTDEIIENKTYSQVEIDVLQEQIDQLSQYKPKELTDDEIKIQQKLEAIWQREVTQTLKEEGVEVFADFINVSVDDTETLNNQITKLKEIIGQLELANGYKPTNHKKVDGYSIAKKNKDTKSMISQKLNF
>NZ_CP016360.1|WP_073340285.1|3652693_3653575_-|DUF5309-domain-containing-protein
MLDSKKLTTQENIHLTDEIALVAPIATPFFTLLMSKGLYVDSKGKFHTWREKTLDGTADITVDEGVDATQFVQSGRAELNNIMEIFYKATSVSGTAQATGAVNDLFAQEINDRLIELAIGMEKKLINGVKNDGASGKRQMDGILKFVDAGNVVNGATTNVLQEKEVKELVKKLWNAGNENGEFYALVGADIKDQIDELYKDRYSYQHVTTDFGIVVNSVETSYGKVNFILDRYMPADKIVAFDVNALKVAFLRQPQFEQLGKTGDNVKGQVVAEATLEVGSKKAVAVYNLKQA
>NZ_CP016360.1|WP_073340291.1|3652420_3652594_-|helix-turn-helix-transcriptional-regulator
MNMKDMYIIERRKKKIRLRQLAEYIGCSPSLLSRYETGDCEMDKEKVKKYKEYIDSY
>NZ_CP016360.1|WP_073340296.1|3651407_3652223_-|hypothetical-protein
MLKEFKGKFPQWVNESGDYTVCLSDDLDSLVGASILKRVKGYEIKHFYDFNNFYSVDGDKRKAIGVDIALEKGMTWDNHVVRLSRYGKVNPLSANPNVIENINRENYTKKYAMSTALLMWSFYGLPLPESDEGKMLLLSIDSSYKGHYTGFKAVQNEWLRKLGFEELIDIQNKYTLKDFANIKKKYNSSMKIELVNGQLQTEMYLEGISKVLGLPIELPICCFKLKKRFQREKIELRNHSSCTKDMVEEKYEKEIFSMALTQKNTISLTFK
>NZ_CP016360.1|WP_073340300.1|3651168_3651375_-|hypothetical-protein
MFQEKEYFFCYSTNLHEFLRYEKGIKYICTAFHDTTNKRFWLFERDEKLLNALDEYSKHGKKLGFKNK
>NZ_CP016360.1|WP_073340305.1|3650066_3651131_-|hypothetical-protein
MKMTEDNYIQIPNVAFGFGTECKLNNDELKVFAYLQFMKNVGTMNIRTHVTIIVEDLGWTTSKASRDNAKAGKALEGLRDKGYITLSFNGDVKKNALAIEINDEMKKVVAESTVDWKTKAFKFSGYTEIKANEYNLAEENDYHLAIMTYHKWRENLEKKYGFKYDICDKEWCEVLELGMTRTREIINDCTFLTKVSGKKYQDENGQWKQETNHYVKSTSVKPDLKEIETENKNLTILEKEREKVTDENVLLDGDVFKQIFDKNTFIEFKGYKAWKETTCDYVKKAGQKKFEILEKAGQSWVGEKLEREYQERLENQQRTHRMMEIHMNDFEGYEEFQPSYKPKKVEENNFFDDM
>NZ_CP016360.1|WP_073340309.1|3649665_3650049_-|hypothetical-protein
MTLKEALKKVTKENRMYFNYKFPDTRFNQTIQPKNEEEFLISVGRKTMNGFTNWEKTPEYANLVALYLQSKMIDDIYKIYDVVRVKALEGDDKSITTFLKLNKEINTIVKAGRELIDDEIEEDGLSL
>NZ_CP016360.1|WP_073340313.1|3648088_3649666_-|DNA-packaging-protein
MSKKLTKEEKLQIINNDPVLWLKNFVKITTNTGEYINFVVNDQQKKFIDEMGRFNVIAKARQIGFSTMSLALCLWMAMNRPRTNYMIVSYKQESSTSLFDKLKMMYDDLPHDKFKFPKDVQNNRGQMKFDNGSSITLATAGGKDVGRGTTYEYILLSEFAFYENQESILLSAEQALAKSKTSKLVIETTSNGFNPYQKLFMNAYKGESKYKAFFFPFYSSSYAKQFKDDYDEAEIWYKENNKGKRLTKDDIEQDELYLYEQGATLKQLMWRRWKLLDMTLQQFYQEFPATPMESFISSGLNVFDQQKIVERLKYISKPLQYREIKMIIPDSIAKYIGKSLMIYELPVKGVKYYGGVDTASGSGGDYSTISILNGDGEQVLSFYDNKIPVYEFAKLLDIIGKFYNYAFLTVERNSFGTPILERLRKEYEYMNLYKHKIFNQQLGKKQLQLGYQTTQVTKNIMITDLKEQFELGMILINCQETLEQMQIFVETDGKTGNKKGNDKHDDCVIAMALAIQGIKQNKWYV
>NZ_CP016360.1|WP_073340317.1|3647470_3648034_-|hypothetical-protein
MNWTDAFIDSLKDWNELCTVKNIKLEDVLGQIGYRIGLQGLIDNSTIEGLEDRINFLVTEERMDERFLIESLINQVTVILKGMLSELGENIIQAEKMKETLEGQDSLKDIYDRKLAELKSPSYAYNARHQIDTWEFVINKKFSSTIKKQFEIEDFMKASERVKKDFAKIPQEDLNLSFGELHKKLNK
>NZ_CP016360.1|WP_073340322.1|3646021_3647422_-|phage-portal-protein
MNLKEYIKTVHNGNSFWFVDEVSHFENQKRILDTIEKKKYLDGKHAISNKVVENYNGKPYEQRAILLQYAKLIVNLETTYLLKKPLTFTGEEKIVSDMKRVYKKGKYDKIDFDLLSNLVKYGNAYEYVFVNSGGEVSSKVIPTECGYPIYNDELDMIAFVEYYTSLESDFYIVYTPEEVVKYSTIGGTDLHVIGSYNNVSGLPIHYRTNNELNEAFGKSDLDDFINIIDAMEDLLSKFSDSFYKHHNPIPVVIGQQLKGEGLNPHIVGGGITLDDGADFKMVSNDINHKAFEVIFNTLMQQLINIASVPAVALNASDVSNLSEMSMRMLYQLADMKAGLNERYLREGLEHRTDKVVGLLGRQGKTYSEDAIESLDMVFHYSRPVNETEVIDNLVKMYDVGAISIESLVAINPYVSNEHLELKRILEREQRVSEQVNEKVNEHEQVQAKTKDAKADVATKKEDAVEK
>NZ_CP016360.1|WP_073340277.1|3655212_3656127_-|tyrosine-type-recombinase/integrase
MELEDVIEEYLYHCMAKGFTPKTMKNKRQEMKQLRKFLMDEKGISELEAINTLHLKQYVRAKHGEGLQPQSIVSMFKMVRAFFSWCQKEEYLKENIAKKVEMPKVPKKLLKGFTVQEVSAMIDAFSYKNYIEARNKAIVAMLSDCGLRAMEIRGLLTKNVKETTILVNGKGNKERIMFISPPLKKILIRYERLRKEYLKDKIVKTDHYFLSYTADPLSHMGIYNVVKEAGKRVEVEEVRCSPHTFRHFFAVQCILNGIDIFTLSKLLGHSDVSTTQRYLQSLEDFELIKKAMPSSPLMNIGRSS
>NZ_CP016360.1|WP_001123317.1|3656318_3656540_-|YneF-family-protein
MPIWLGILVGVVALVAGVALGFFIARKYMMNYLQKNPPINEQMLKMMMMQMGQKPSQKKINQMMSAMNKQQMK
>NZ_CP016360.1|WP_000860636.1|3656618_3657059_-|sporulation-inhibitor-of-replication-protein-SirA
MKTYELYLIQEDIAKAYFGREYLFFDLFARFSESGSLSEKKVLYKQMMYITMPLQVMKIHHKLEQALRVLGKYDRTHHTHTIYTGAEYGEIMVKPHYIRMNTSGNVSMETTFFEVLRKCELTFLAMDYENTKYGWLNPLKQVRTYV
>NZ_CP016360.1|WP_000019766.1|3657215_3659216_-|transketolase
MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDLMEGVSAEASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIAKAIEEAKADEKRPTLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYDNFRKTVQDVGETAQAEWNTMLGEYAQAYPELANEFQAAMNGQLPEGWEQNLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDDYSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAKGAYVVSASKKETADVILLATGSEVSLAVEAQKALAVDGVDAAVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDVLGIDTFGASAPGEKIMEEYGFTVENVVRKVKEML
>NZ_CP016360.1|WP_000047894.1|3659512_3660316_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MSKTTIIVPKPKKPSVYRSFIFIALTFVYIWAFSGVPLEGIKETAGEITKAIMTGILTPDWAYVSLPDGEDLLHGLIDTLAIAILGTFISAFLSVPFAFWAATNMSSGKLTSGFGKFVLSFVRTFPELVMALLFIKAVGPGSFAGVLALGLHSIGMLGKLYSEGIENIDKGPTEALLATGANRFQILWYAVLPQVLPDFLSYTLYRFEINVRSAAILGVIGAGGIGTPLIFALSSRNWSRVGIILLGIILMVIIIDLISSSIRKRIV
>NZ_CP016360.1|WP_001000763.1|3660315_3661110_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MNDVTIYSKSIPKPPSKLKHMLTFILFILLLWGSSIQVDASFSKLVVGFPNIMDLLKEMVPPDWSYFQVITTAMLDTIRMAIIGTTLGAILAIPLALFAASNVFTSTFLYSPARLILNFIRTIPDLLLAAIFVAIFGIGPLPGILALTFFSIGLVAKLLYESIESIDPGPLEAMTAVGANKVQWIVYGVIPQVKAHFVSYVLYTFEVNVRAAAVLGLVGAGGIGLYYDRTLGFLQYQQTASIIIYTLVVVLVIDYVSTLLREKL
>NZ_CP016360.1|WP_000569240.1|3661106_3661880_-|phosphonate-ABC-transporter-ATP-binding-protein
MIEFRNVSKVYPNGTKGLNNINLKIQKGEFVIMVGLSGAGKSTLLKSVNRLHEITEGEIMIECESITAAKGKDLRRMRRDIGMIFQSFNLVKRSTVLKNVLAGRVGYHSTLRTTLGLFPKEDVELAFQALKRVNILEKAYARADELSGGQQQRVSIARALAQEAKIILADEPVASLDPLTTKQVLDDLKKINEDFGITTIVNLHSIALARQYATRIIGLHAGEIVFDGLVEAATDEKFAEIYGDVAQKSELLEVAAK
>NZ_CP016360.1|WP_000915065.1|3661963_3662902_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein
MLKKVFAMSTTVVLAAGLLSGCGTKESSASKNEDTKKGYVPKTLNVQFVPSQNADTLEAKAKPLEKLLSDKLNIPVKVSISTNYNTIVEAMASKQVDVGFLPPTAYVLAHEKKAANVILQAQRFGVEDETGAPTKDLVDYYKSEFVVKKDSNINSVKDLKGKKIGYQDVTSSAGYVWPAAVLLKEGIDPLKDVKPVTLKGHDQSLIALLNGDVDAAVVFQDARNIVKKDYPNIFEQTKIVKFTEKIPNDTISVRSDLDEEWSKKLQDAFIEIGKNEEGHKIIKEVYSHEGYVKSDDSKFDIVREYGKKVKTQ
>NZ_CP016360.1|WP_000437455.1|3663087_3664671_+|2',3'-cyclic-nucleotide-2'-phosphodiesterase
MEQNQTVTLNILLTSDIHGTVYPIHYQDNSPAELGLAKISTLIKKERSQNTNVLLIDNGDFIQGTPFTYHYVTYEKNKKNPMSLLANYLQYDAAIIGNHEFNYGMGILNNAVTTANFPYLSANILDKNIKKPYFGKPYIIKQIESNIKIAILGVTTHYITNWEQPHHIKDLQFEDALETTKKWVSYIRKHEKPDLLVVAYHGGVERDLQTGVPTEVLTGENQGYAMCHEIEDIDILLTGHQHREIAHTMANGVTILQTGCNGNSVGKVKITFEKTKHKWVKKESSSELLSVQGVEADQDALSLVADYEEKTQKWLDQPIGIIQGDMQISDAMQTRLHDHPFIEFINKIQMDIANVSISCTSLFHNTSPGFPEHVTMRDIVSNYIYPNTLKVIRLTGADIKNALELSASYFTLKTDGSITVSPTYIEPKPQHYNYDMWEGISYVLNISKPIGERVESLQHNSAPLNMNEEYDVVMNNYRASGGGNFFMFQNKPVVKDIPTDMSELIANYILEHKTIEATVNNNWKVIK
>NZ_CP016360.1|WP_000607016.1|3664710_3664950_-|DUF896-domain-containing-protein
MINHELVERINFLAKKAKAEGLTEEEQRERQSLREQYLKGFRQNMLNELKGIKVVNEEGTDVTPTKLKALKKQDNARLN

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Crispr_ID: NZ_CP016360_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016360_3

5271455-5271588

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP016360_3

>merge|NZ_CP016360|3|5271455-5271588|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGGTTCTTCTTTTTTGTCACTAGTTGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP016360|3|3|5271455-5271588|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGG	TTCTTCTTTTTTGTCACTAGTTGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016360.1\|WP_000411274.1\|5278518_5279823_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP016360.1\|WP_000998925.1\|5282579_5284082_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP016360.1\|WP_000467938.1\|5267502_5268180_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP016360.1\|WP_000931959.1\|5268524_5268959_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP016360.1\|WP_001207147.1\|5265806_5266508_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP016360.1\|WP_000757791.1\|5263806_5264688_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP016360.1\|WP_016123874.1\|5275858_5276662_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226297
NZ_CP016360.1\|WP_000144450.1\|5272475_5273180_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP016360.1\|WP_000672664.1\|5277292_5278312_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP016360.1\|WP_000008901.1\|5271132_5271267_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016360.1\|WP_001068730.1\|5263105_5263789_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|376775
NZ_CP016360.1\|WP_000367491.1\|5281057_5282578_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP016360.1\|WP_000057889.1\|5280618_5280855_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP016360.1\|WP_001185929.1\|5274203_5275211_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP016360.1\|WP_000393126.1\|5266497_5267241_-\|capsular-polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP016360.1\|WP_002005985.1\|5279862_5280573_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP016360.1\|WP_000544012.1\|5270551_5270824_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP016360.1\|WP_000170866.1\|5273179_5274022_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP016360.1\|WP_016123873.1\|5264927_5265695_-\|phosphotyrosine-protein-phosphatase-(capsular-polysaccharide-biosynthesis)	unknown	unknown	gnl\|CDD\|226870
NZ_CP016360.1\|WP_000457978.1\|5269389_5270391_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563

Protein	Function_ID	Function_description	E-value
NZ_CP016360.1\|WP_000998925.1\|5282579_5284082_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	6.06753e-178
NZ_CP016360.1\|WP_000467938.1\|5267502_5268180_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.12499e-81
NZ_CP016360.1\|WP_000931959.1\|5268524_5268959_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP016360.1\|WP_001207147.1\|5265806_5266508_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	3.60035e-83
NZ_CP016360.1\|WP_000757791.1\|5263806_5264688_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP016360.1\|WP_016123874.1\|5275858_5276662_-\|hypothetical-protein	gnl\|CDD\|226297	COG3774, OCH1, Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane].	4.51885e-17
NZ_CP016360.1\|WP_000393126.1\|5266497_5267241_-\|capsular-polysaccharide-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	5.00781e-84
NZ_CP016360.1\|WP_000672664.1\|5277292_5278312_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	2.63722e-134
NZ_CP016360.1\|WP_001068730.1\|5263105_5263789_-\|sugar-transferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	3.10998e-106
NZ_CP016360.1\|WP_000367491.1\|5281057_5282578_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	2.28211e-151
NZ_CP016360.1\|WP_000057889.1\|5280618_5280855_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	1.23409e-23
NZ_CP016360.1\|WP_001185929.1\|5274203_5275211_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.78285e-31
NZ_CP016360.1\|WP_000170866.1\|5273179_5274022_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.20989e-89
NZ_CP016360.1\|WP_002005985.1\|5279862_5280573_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	5.16446e-34
NZ_CP016360.1\|WP_000544012.1\|5270551_5270824_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP016360.1\|WP_000411274.1\|5278518_5279823_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP016360.1\|WP_016123873.1\|5264927_5265695_-\|phosphotyrosine-protein-phosphatase-(capsular-polysaccharide-biosynthesis)	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.00103e-106
NZ_CP016360.1\|WP_000144450.1\|5272475_5273180_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	5.76202e-05
NZ_CP016360.1\|WP_000457978.1\|5269389_5270391_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0

>NZ_CP016360.1|WP_000008901.1|5271132_5271267_-|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEEFEREE
>NZ_CP016360.1|WP_000544012.1|5270551_5270824_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP016360.1|WP_000457978.1|5269389_5270391_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP016360.1|WP_000931959.1|5268524_5268959_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP016360.1|WP_000467938.1|5267502_5268180_-|CpsD/CapB-family-tyrosine-protein-kinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHIRSIIVTSADPGDGKTTTISNLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKLLGVVLNDKREEKEQYGYY
>NZ_CP016360.1|WP_000393126.1|5266497_5267241_-|capsular-polysaccharide-biosynthesis-protein
MEETISLKELFHILKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGAAIQLGEIQSNIQLTNTYKVIIKSPVILDQVKEKLGLDVTTQDLNEKIEVGNEKDSQVVTVTAIDKDPKLARDIANTTAEVFKGEIAKIMSVDNVTVLSKAEVAESQSPIKPRPMLNVAIAFVVGLMASVGLAFLLEYLDNTVKKEEDVENLLGLPVLGIVARMDEETMNVKSHAPSSRKVRGQTIGS
>NZ_CP016360.1|WP_001207147.1|5265806_5266508_-|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAIDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTHSERLEKCVQTTLVDNLHFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASILVVRSESTEKETAVKAKGLLESAKGKLLGVVLNDREREEGLYYYYGAN
>NZ_CP016360.1|WP_016123873.1|5264927_5265695_-|phosphotyrosine-protein-phosphatase-(capsular-polysaccharide-biosynthesis)
MIDLHCHILPGIDDGAQTVTDSLAMAQQAVSEGIHTIVATPHHQNGKYVNERTSIIHRVKQLNDELQQYNIPLTVLPGQEVRLYGDLLEDYEVGKIVTLNETNKYIFIEFPSNHVPRYAEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNIVNKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMVASDAHNTTSRGFHLAESYELIAKEFGTSVMSDLKENSYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP016360.1|WP_000757791.1|5263806_5264688_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIVVTGKGKRAIEDHFDHSFELEQNLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYESTQSSVIGVQTVPENETHRYGIIDPVEQNERRYQVRQFVEKPAQGTAPSNLAIMGRYVLTSEIFMFLENQQTGAGGEIQLTDAIQRLNEIQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQHEELKEELMEYMNEIVKRENVYV
>NZ_CP016360.1|WP_001068730.1|5263105_5263789_-|sugar-transferase
MNPLKVLDENVKENSKELDLSEINARKGYMATKRCMDIIGALCGLIFLSPIFLVVALLIKYEDPKGGVFFKQMRVGKDGKEFYMYKFRSMVTDAEERLQDLLKYNEVSGAMFKIKEDPRITRIGKIIRKTSIDELPQLINVLKGDMSLVGPRPPLPREVKEYTTYDKQRLMVTPGCTGLWQVSGRNSIGFAEMVKLDIYYIENRNLIFDLKIICRTFVVVIKPNDAS
>NZ_CP016360.1|WP_000144450.1|5272475_5273180_-|ABC-transporter-permease
MTFSMRRVSAIFRKEVQDFKTNSQVLLMAFLPIILSFLFSRFGVGKEMLGITTITAFLFVAGFVQSMVIAEEKEKHTLRVLMLSPASSVEVLLGKSLLTSGLTMVICIANLFILDQLNINLPLVGLIFLCGTILFIVLGTMIGLLASSVPQTSIIGMPILMTMYLAVQFEPMVENKVIKTMIGYLPTSHIVKALKSLVGGAGFSSISGHVLNVAVWLIISLVVCLIVYKKKQLD
>NZ_CP016360.1|WP_000170866.1|5273179_5274022_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFSGKTALRNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLTQVNLLDDKKTPVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNEEGTTIFLTTHNMDEAETLCNRIAFLCGGEIVALDTPENLRLQYAKDQIEVVLKGKRKEVVQKDELGANRISEWMKKGELLSIHSHEPTLGDIFIEVTGRGL
>NZ_CP016360.1|WP_001185929.1|5274203_5275211_-|ATP-binding-cassette-domain-containing-protein
MALLELKQLGKTNQLPAIELKVEKGQCIVLQCNNHTAKVLHRIIIGEEEASTGNVLFEGEVIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYESKVSIEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRMMIHNPDLIILEEPEQNVDIESTVIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEVEEVGEEKVIQMIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLSELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP016360.1|WP_016123874.1|5275858_5276662_-|hypothetical-protein
MNTNIPKIIHYCWFGGKEKPDHIKKYMKTWDGLKDYKIVEWNEKTFDIENNKFVKDAYEGRKWAFVSDYVRLKALYEHGGIYLDTDVELNKNFNDILSNDMFLGFIYDCSIGTAVIGAKPKHPLIKELLDIYEEITFCDNSYIGFTVKRFPNVKLINNNDLFTLFLLNKYKEFKLNNKYQELDGLTIYPKNYFEVQPIFGSKYTVHWCEGSWTGKENGKEVKKYKKLIKSFLASIPFVHFNAVVTHLQHRKKLSKLPFYKYYVEHNK
>NZ_CP016360.1|WP_000672664.1|5277292_5278312_-|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVETLPVEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGGKKNNADVTDTVKDQVYKSKDELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAVDYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVAIKTMNDYEGKLMVKK
>NZ_CP016360.1|WP_000411274.1|5278518_5279823_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVAATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVNFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP016360.1|WP_002005985.1|5279862_5280573_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVLFLVGYREMKPISDEQKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKEKANIQKWEVEQSPDGYKATSYKKLSSYEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQNMNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP016360.1|WP_000057889.1|5280618_5280855_-|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMKSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP016360.1|WP_000367491.1|5281057_5282578_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCTAMSDDKKNSIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKSRASNEAAMKYVISGGIGTAITLFGMSYLYGITGSTNIVDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGATTPVTAFLGTISKIAGFLLIIRLFLMIFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNIKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQNNEENITIFTGLYKRSPFTAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP016360.1|WP_000998925.1|5282579_5284082_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAIVLACTYASGKNLSLFDEKMKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLATLAAIAAFSIKRNLKAFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIVELKEILRSVNAEGALVIPSSLQLSVFIAIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDVATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLASLNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSDITALGGLAKSVPVLSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016360_2	2.1\|3654291\|26\|NZ_CP016360\|CRISPRCasFinder	3654291-3654316	26	NZ_CP014236	Moraxella osloensis strain CCUG 350 plasmid unnamed3, complete sequence	50854-50879	4	0.846
NZ_CP016360_2	2.1\|3654291\|26\|NZ_CP016360\|CRISPRCasFinder	3654291-3654316	26	NC_001949	Lactococcus lactis DPC3147 plasmid pMRC01, complete sequence	4326-4351	5	0.808
NZ_CP016360_2	2.2\|3654352\|27\|NZ_CP016360\|CRISPRCasFinder	3654352-3654378	27	AP014440	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C27-MedDCM-OCT-S30-C70, * SEQUENCING IN PROGRESS *, 2 ordered pieces	24127-24153	5	0.815
NZ_CP016360_2	2.2\|3654352\|27\|NZ_CP016360\|CRISPRCasFinder	3654352-3654378	27	AP014441	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C27-MedDCM-OCT-S33-C93, * SEQUENCING IN PROGRESS *, 11 ordered pieces	20535-20561	5	0.815
NZ_CP016360_2	2.2\|3654352\|27\|NZ_CP016360\|CRISPRCasFinder	3654352-3654378	27	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	1167169-1167195	6	0.778
NZ_CP016360_2	2.2\|3654352\|27\|NZ_CP016360\|CRISPRCasFinder	3654352-3654378	27	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	1171849-1171875	6	0.778
NZ_CP016360_3	3.1\|5271478\|31\|NZ_CP016360\|CRISPRCasFinder	5271478-5271508	31	JX238501	Bacillus phage phiAGATE, complete genome	124559-124589	8	0.742
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	9	0.735
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47181-47214	11	0.676
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47565-47598	11	0.676
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47949-47982	11	0.676
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48333-48366	11	0.676
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48717-48750	11	0.676
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49101-49134	11	0.676
NZ_CP016360_3	3.2\|5271532\|34\|NZ_CP016360\|CRISPRCasFinder	5271532-5271565	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49485-49518	11	0.676

1. spacer 2.1|3654291|26|NZ_CP016360|CRISPRCasFinder matches to NZ_CP014236 (Moraxella osloensis strain CCUG 350 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.846

gtgaccattttaccttttttaaaata	CRISPR spacer
atgaccatttaaccttatttaaaatt	Protospacer
.********* ***** ********

2. spacer 2.1|3654291|26|NZ_CP016360|CRISPRCasFinder matches to NC_001949 (Lactococcus lactis DPC3147 plasmid pMRC01, complete sequence) position: , mismatch: 5, identity: 0.808

gtgaccattttaccttttttaaaata	CRISPR spacer
ataactattttaccttttttaaaaat	Protospacer
.*.**.******************

3. spacer 2.2|3654352|27|NZ_CP016360|CRISPRCasFinder matches to AP014440 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C27-MedDCM-OCT-S30-C70, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 5, identity: 0.815

gtacgtgttttgtatttgagaaataat	CRISPR spacer
gtatcaagtttgtatttgagaaataat	Protospacer
***.  . *******************

4. spacer 2.2|3654352|27|NZ_CP016360|CRISPRCasFinder matches to AP014441 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C27-MedDCM-OCT-S33-C93, *** SEQUENCING IN PROGRESS ***, 11 ordered pieces) position: , mismatch: 5, identity: 0.815

gtacgtgttttgtatttgagaaataat	CRISPR spacer
gtatcaagtttgtatttgagaaataat	Protospacer
***.  . *******************

5. spacer 2.2|3654352|27|NZ_CP016360|CRISPRCasFinder matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 6, identity: 0.778

gtacgtgttttgtatttgagaaataat	CRISPR spacer
ctacgggttttgtgtttgagaaattcg	Protospacer
 **** *******.**********

6. spacer 2.2|3654352|27|NZ_CP016360|CRISPRCasFinder matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 6, identity: 0.778

gtacgtgttttgtatttgagaaataat	CRISPR spacer
ctacgggttttgtgtttgagaaattcg	Protospacer
 **** *******.**********

7. spacer 3.1|5271478|31|NZ_CP016360|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

ttcttcttttttgtcactagttgaaccgctt	CRISPR spacer
ctaaccttttttgccactagttaaaccgccc	Protospacer
.*  .********.********.******..

8. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

9. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

10. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

11. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

12. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

13. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

14. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

15. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

16. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

17. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

18. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

19. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

20. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

21. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

22. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

23. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

24. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

25. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

26. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

27. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

28. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

29. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

30. spacer 3.2|5271532|34|NZ_CP016360|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

257354 : 265302

uncultured_virus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000917311.1\|257354_257639_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8
WP_001029993.1\|257677_259312_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.5e-157	58.0
WP_000743909.1\|259718_261257_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	8.8e-22	31.7
WP_000833082.1\|261641_262967_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	6.4e-45	30.1
WP_000929885.1\|263111_263813_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.3e-40	36.9
WP_000719223.1\|263796_265302_+	aminopeptidase AmpS	W8CYF6	Bacillus_phage	5.4e-32	30.3

DBSCAN-SWA_2

297579 : 305955

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625682.1\|297579_298887_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.3
WP_001170544.1\|298975_299695_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000278823.1\|299687_299942_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666775.1\|299938_300622_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000055555.1\|300605_302825_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	8.8e-164	41.2
WP_000879025.1\|302809_304225_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-55	35.4
WP_001262439.1\|304330_305371_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.9
WP_000088589.1\|305367_305955_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.1e-28	37.4

DBSCAN-SWA_3

1832065 : 1840741

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000755507.1\|1832065_1833352_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.4e-11	31.5
WP_001194314.1\|1833451_1834216_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000453886.1\|1834456_1836217_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.3e-274	98.4
WP_000612413.1\|1836302_1836980_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-122	98.7
WP_001231631.1\|1836976_1838050_+	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	3.9e-186	97.5
WP_000823542.1\|1838074_1838662_-	DUF3139 domain-containing protein	NA	NA	NA	NA
WP_000818985.1\|1838858_1839578_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_001258500.1\|1839868_1840741_+	aminoglycoside 6-adenylyltransferase	A0A1X9I6F2	Streptococcus_phage	7.4e-66	45.1

DBSCAN-SWA_4

2191142 : 2249909

Bacillus_phage(43.75%)

tail,portal,integrase,terminase,bacteriocin

attL 2184703:2184725|attR 2255723:2255745

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2184703:2184725	attL	NA	NA	NA	NA
WP_073339430.1\|2191142_2192279_-\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	2.9e-54	35.4
WP_073339433.1\|2192543_2192981_+	helix-turn-helix domain-containing protein	A0A142F1P0	Bacillus_phage	1.0e-36	59.2
WP_073339435.1\|2193393_2193738_+	hypothetical protein	NA	NA	NA	NA
WP_073339438.1\|2194152_2194299_+	Fur-regulated basic protein FbpA	NA	NA	NA	NA
WP_073339440.1\|2194295_2194682_+	hypothetical protein	A0A2H4J134	uncultured_Caudovirales_phage	9.3e-13	38.2
WP_073339443.1\|2194760_2195468_+	DUF723 domain-containing protein	G9J2C6	Bacillus_phage	1.0e-12	55.0
WP_073339445.1\|2195467_2196232_+	DNA replication protein	A0A0N7GFF0	Paenibacillus_phage	9.9e-75	55.3
WP_073339447.1\|2196570_2197245_-	hypothetical protein	NA	NA	NA	NA
WP_073339450.1\|2197374_2197656_+	hypothetical protein	A0A0H3V0M3	Geobacillus_virus	3.4e-12	48.3
WP_073339452.1\|2198074_2199418_+	DNA helicase	A0A2H4IZL9	uncultured_Caudovirales_phage	1.5e-134	55.1
WP_073339455.1\|2199444_2200461_+	hypothetical protein	A0A2H4J6E6	uncultured_Caudovirales_phage	2.6e-70	42.6
WP_085962721.1\|2200468_2200654_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000568403.1\|2200718_2200922_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_073339458.1\|2201036_2202254_+	hypothetical protein	A0A288WGM1	Bacillus_phage	5.4e-99	47.7
WP_073339460.1\|2202565_2203213_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_073339463.1\|2203725_2204478_+	single-stranded DNA-binding protein	A0A0N9SJW5	Paenibacillus_phage	2.2e-58	48.8
WP_073339466.1\|2204490_2204898_+	hypothetical protein	NA	NA	NA	NA
WP_073339472.1\|2206420_2209261_+	hypothetical protein	A0A0N9S7Z3	Paenibacillus_phage	5.9e-104	40.3
WP_073339474.1\|2209253_2209403_+	BC1881 family protein	NA	NA	NA	NA
WP_083605814.1\|2209483_2209732_-	alpha/beta-type small acid-soluble spore protein	Q77YX0	Bacillus_phage	2.0e-08	75.0
WP_083605815.1\|2209848_2210901_+	hypothetical protein	A0A0N9SHN6	Paenibacillus_phage	5.2e-90	59.5
WP_073339479.1\|2210887_2211412_+	hypothetical protein	NA	NA	NA	NA
WP_073339481.1\|2211765_2212509_+	FAD-dependent thymidylate synthase	A0A142F1S2	Bacillus_phage	2.5e-86	66.7
WP_073339483.1\|2212676_2213042_+	hypothetical protein	NA	NA	NA	NA
WP_073339486.1\|2213043_2213673_+	hypothetical protein	J9Q953	Bacillus_phage	1.8e-34	42.2
WP_073339489.1\|2213739_2214186_-	hypothetical protein	NA	NA	NA	NA
WP_073339492.1\|2214642_2216130_+	DNA (cytosine-5-)-methyltransferase	Q77YW9	Bacillus_phage	1.1e-106	44.4
WP_073339495.1\|2216134_2216539_+	sigma-70 family RNA polymerase sigma factor	A0A0N9RZI0	Paenibacillus_phage	1.2e-15	41.0
WP_073339498.1\|2216538_2217066_+	hypothetical protein	A0A0N7GFF4	Paenibacillus_phage	2.4e-19	44.0
WP_073339501.1\|2217343_2218747_+	hypothetical protein	NA	NA	NA	NA
WP_073339505.1\|2218819_2219059_-	hypothetical protein	NA	NA	NA	NA
WP_073339508.1\|2219444_2220632_+	hypothetical protein	NA	NA	NA	NA
WP_073339511.1\|2220940_2222770_-	DUF4365 domain-containing protein	NA	NA	NA	NA
WP_000673113.1\|2223081_2223366_+	hypothetical protein	NA	NA	NA	NA
WP_073339517.1\|2223608_2224046_+	hypothetical protein	NA	NA	NA	NA
WP_001180308.1\|2224308_2224950_-	DUF4145 domain-containing protein	M1PSB6	Streptococcus_phage	6.7e-32	34.4
WP_073339520.1\|2225072_2225471_+	hypothetical protein	A0A0N7GFF5	Paenibacillus_phage	4.0e-35	65.0
WP_073339522.1\|2225942_2226491_-\|integrase	site-specific integrase	A0A2H4J6I5	uncultured_Caudovirales_phage	5.9e-45	59.0
WP_073339525.1\|2226935_2228381_+\|terminase	phage terminase large subunit	A0A0N9RZA7	Paenibacillus_phage	1.1e-135	52.6
WP_073339528.1\|2228397_2229912_+\|portal	phage portal protein	A0A142F1L7	Bacillus_phage	7.3e-69	30.7
WP_073339531.1\|2229997_2230651_+	scaffolding protein	A0A2H4IZP8	uncultured_Caudovirales_phage	1.1e-08	44.4
WP_073339534.1\|2230715_2231840_+	hypothetical protein	NA	NA	NA	NA
WP_073339537.1\|2231890_2232085_+	hypothetical protein	NA	NA	NA	NA
WP_083605817.1\|2232100_2232442_+	hypothetical protein	NA	NA	NA	NA
WP_073339540.1\|2232446_2233253_+	hypothetical protein	NA	NA	NA	NA
WP_073339542.1\|2233256_2233631_+	hypothetical protein	NA	NA	NA	NA
WP_073339544.1\|2233630_2233990_+	hypothetical protein	NA	NA	NA	NA
WP_073339547.1\|2233991_2234399_+	hypothetical protein	NA	NA	NA	NA
WP_073339550.1\|2234416_2234926_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_073339553.1\|2235005_2235380_+	hypothetical protein	NA	NA	NA	NA
WP_073339557.1\|2235421_2235724_+	hypothetical protein	NA	NA	NA	NA
WP_083605818.1\|2235747_2239533_+\|tail	phage tail tape measure protein	A6M961	Geobacillus_virus	7.0e-12	43.5
WP_073339560.1\|2239510_2241025_+\|tail	phage tail family protein	A0A0S2MV63	Bacillus_phage	9.1e-213	77.7
WP_073339562.1\|2241021_2245329_+	hypothetical protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	63.6
WP_073339564.1\|2245344_2245719_+	hypothetical protein	A0A0S2MVE0	Bacillus_phage	3.0e-64	95.9
WP_000480958.1\|2245757_2245994_+\|bacteriocin	bacteriocin biosynthesis protein	A0A1B0T697	Bacillus_phage	3.9e-14	54.1
WP_073339567.1\|2245990_2247088_+	N-acetylmuramoyl-L-alanine amidase	A0A0A7AQV3	Bacillus_phage	2.9e-136	66.8
WP_073339570.1\|2247142_2248054_-	NADH dehydrogenase	NA	NA	NA	NA
WP_073339573.1\|2248290_2249562_+	Y-family DNA polymerase	O64031	Bacillus_phage	3.8e-103	47.1
WP_073339630.1\|2249567_2249909_+	YolD-like family protein	A0A2H4JEH6	uncultured_Caudovirales_phage	2.9e-10	33.3
2255723:2255745	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3665793 : 3677524

Bacillus_phage(50.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000413738.1\|3665793_3666414_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	8.2e-19	62.2
WP_000976237.1\|3666504_3667308_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_000031387.1\|3667308_3667851_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_001102628.1\|3667843_3668167_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_000725955.1\|3669205_3670261_-	SH3 domain-containing protein	A0A1B0T6C8	Bacillus_phage	2.4e-143	69.2
WP_000570187.1\|3670257_3670497_-\|holin	holin	A0A0A7AR38	Bacillus_phage	1.3e-25	78.7
WP_000348875.1\|3670496_3670733_-	hypothetical protein	A0A2H4J382	uncultured_Caudovirales_phage	1.8e-14	87.2
WP_002026207.1\|3670810_3671017_-	hypothetical protein	NA	NA	NA	NA
WP_001051360.1\|3671365_3672187_-	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	1.2e-20	38.6
WP_025921790.1\|3672536_3673514_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.1e-33	43.9
WP_000464425.1\|3673752_3674139_-	DUF1492 domain-containing protein	A0A288WG73	Bacillus_phage	2.6e-47	71.4
WP_000511413.1\|3674257_3675130_-	DnaD domain protein	A0A2H4J394	uncultured_Caudovirales_phage	1.9e-93	72.3
WP_001189065.1\|3675282_3675477_-	hypothetical protein	A0A1C8E9A1	Bacillus_phage	1.7e-15	71.0
WP_000531225.1\|3675488_3676247_-	phage regulatory protein	A0A2H4JBC7	uncultured_Caudovirales_phage	9.2e-97	69.0
WP_000283431.1\|3676449_3676662_-	hypothetical protein	A6M975	Geobacillus_virus	1.6e-11	63.0
WP_000241483.1\|3676852_3677524_+	helix-turn-helix domain-containing protein	A0A2H4J441	uncultured_Caudovirales_phage	5.7e-34	41.0

DBSCAN-SWA_6

4406086 : 4496877

uncultured_Caudovirales_phage(57.14%)

capsid,tail,tRNA,portal,protease,terminase,head,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000125365.1\|4406086_4407226_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.1e-82	42.3
WP_000354018.1\|4407238_4408291_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_000138162.1\|4408310_4408511_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_000344449.1\|4408507_4409509_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	6.8e-07	26.3
WP_000464511.1\|4409514_4410132_-	Holliday junction DNA helicase RuvA	NA	NA	NA	NA
WP_000823606.1\|4410320_4411265_+	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000871192.1\|4411278_4411809_-	BofC protein	NA	NA	NA	NA
WP_000721223.1\|4412238_4412673_+	hypothetical protein	NA	NA	NA	NA
WP_001093536.1\|4412706_4413351_-	hypothetical protein	NA	NA	NA	NA
WP_089030276.1\|4413529_4415380_-\|coat	spore coat assembly protein ExsA	NA	NA	NA	NA
WP_000025339.1\|4415605_4416712_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_001092227.1\|4416741_4417575_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_001138533.1\|4417594_4419124_-	L-aspartate oxidase	NA	NA	NA	NA
WP_000973770.1\|4419275_4420418_+	aminotransferase class V-fold PLP-dependent enzyme	A0A1X7QGF3	Faustovirus	3.8e-30	28.9
WP_000812275.1\|4420417_4420960_+	transcription repressor NadR	NA	NA	NA	NA
WP_000510677.1\|4421039_4421687_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_000621705.1\|4421791_4422643_-	prephenate dehydratase	NA	NA	NA	NA
WP_001028684.1\|4422739_4424653_-	ABC transporter permease	NA	NA	NA	NA
WP_001011411.1\|4424702_4426625_-	ABC transporter permease	NA	NA	NA	NA
WP_000114528.1\|4426599_4427376_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	3.5e-19	31.0
WP_000865179.1\|4427469_4428552_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_000276723.1\|4428541_4429249_-	response regulator transcription factor	NA	NA	NA	NA
WP_000497128.1\|4429389_4430676_-	GTPase ObgE	NA	NA	NA	NA
WP_001003584.1\|4430675_4431224_-	sporulation protein	NA	NA	NA	NA
WP_000270907.1\|4431937_4432246_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_000855484.1\|4432415_4433804_-	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_000599058.1\|4433871_4434732_-	stage IV sporulation protein SpoIVFB	NA	NA	NA	NA
WP_000797471.1\|4434724_4435471_-	stage IV sporulation protein SpoIVFA	NA	NA	NA	NA
WP_000503309.1\|4435604_4436402_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_000391521.1\|4436404_4437091_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_000975764.1\|4437126_4437672_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_001135488.1\|4437686_4438538_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_000466736.1\|4438579_4439599_-	rod shape-determining protein MreB	NA	NA	NA	NA
WP_086874344.1\|4440267_4441101_+	cytosolic protein	A0A2H4J9W9	uncultured_Caudovirales_phage	1.4e-119	89.2
WP_086874343.1\|4442089_4442422_+	hypothetical protein	A0A1B2AQ49	Phage_Wrath	1.0e-23	57.3
WP_086874342.1\|4442457_4443303_-	SH3 domain-containing protein	J9PQX3	Bacillus_phage	1.2e-118	68.4
WP_033684692.1\|4443302_4443515_-	hypothetical protein	NA	NA	NA	NA
WP_000818883.1\|4443523_4443763_-	peptidase	A0A1B1P7E0	Bacillus_phage	8.0e-31	86.1
WP_001032146.1\|4443852_4444704_-	SGNH/GDSL hydrolase family protein	A0A2H4JE88	uncultured_Caudovirales_phage	8.7e-88	60.1
WP_089030277.1\|4444756_4445263_-	hypothetical protein	A0A2H4J980	uncultured_Caudovirales_phage	1.8e-16	42.3
WP_000793590.1\|4445249_4445432_-	hypothetical protein	A0A2H4JAY5	uncultured_Caudovirales_phage	1.1e-13	61.7
WP_000916428.1\|4445433_4447521_-	hypothetical protein	A0A2H4JG80	uncultured_Caudovirales_phage	4.3e-261	80.6
WP_086709340.1\|4447552_4449274_-	SGNH/GDSL hydrolase family protein	A0A2H4JE88	uncultured_Caudovirales_phage	1.6e-19	34.2
WP_086709342.1\|4449290_4450103_-\|tail	phage tail family protein	A0A2H4J982	uncultured_Caudovirales_phage	4.0e-106	67.4
WP_086874341.1\|4450099_4453651_-\|tail	phage tail tape measure protein	A0A2H4J957	uncultured_Caudovirales_phage	9.2e-224	71.5
WP_086874340.1\|4453667_4453883_-	hypothetical protein	A0A2H4J849	uncultured_Caudovirales_phage	4.3e-28	90.2
WP_086874339.1\|4453888_4454278_-	hypothetical protein	A0A2H4J956	uncultured_Caudovirales_phage	1.1e-56	85.9
WP_086874338.1\|4454288_4454915_-\|tail	phage tail protein	A0A2H4JGN2	uncultured_Caudovirales_phage	2.2e-88	79.8
WP_086874337.1\|4454920_4455304_-	hypothetical protein	A0A2H4J971	uncultured_Caudovirales_phage	9.7e-63	93.7
WP_086874336.1\|4455303_4455633_-	hypothetical protein	A0A1B0T6B7	Bacillus_phage	6.0e-53	91.7
WP_142285468.1\|4455622_4455952_-	hypothetical protein	A0A2H4J9Y9	uncultured_Caudovirales_phage	1.3e-52	94.5
WP_086874333.1\|4455932_4456193_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4J865	uncultured_Caudovirales_phage	7.3e-38	87.2
WP_086874331.1\|4456194_4457511_-\|capsid	phage major capsid protein	A0A1C8E976	Bacillus_phage	3.9e-196	91.7
WP_136999984.1\|4457512_4458094_-\|head,protease	HK97 family phage prohead protease	A0A1C8EA63	Bacillus_phage	3.3e-94	94.3
WP_086874327.1\|4458083_4459268_-\|portal	phage portal protein	A0A2H4JBS9	uncultured_Caudovirales_phage	6.4e-214	94.9
WP_060851542.1\|4459372_4461097_-\|terminase	terminase large subunit	A0A1B2AQ28	Phage_Wrath	0.0e+00	94.9
WP_060851541.1\|4461093_4461528_-	hypothetical protein	A0A1B2APW6	Phage_Wrath	3.9e-68	94.4
WP_000872542.1\|4461647_4462013_-	HNH endonuclease	A0A2H4JA38	uncultured_Caudovirales_phage	9.0e-42	63.6
WP_086874349.1\|4462009_4462291_-	hypothetical protein	A0A1C8EAA0	Bacillus_phage	1.1e-34	80.0
WP_086874325.1\|4462356_4462971_-	SLATT domain-containing protein	NA	NA	NA	NA
WP_038413844.1\|4463141_4463528_-	phage protein	A0A2H4JFW6	uncultured_Caudovirales_phage	4.4e-47	74.4
WP_086874323.1\|4463944_4464286_-	hypothetical protein	A0A2H4JBP0	uncultured_Caudovirales_phage	7.3e-54	96.5
WP_086874321.1\|4464319_4464859_-	nuclease	A0A2H4J819	uncultured_Caudovirales_phage	2.5e-88	90.5
WP_086874348.1\|4464861_4465209_-	hypothetical protein	H0USU9	Bacillus_phage	6.0e-27	53.7
WP_086874320.1\|4465241_4465676_-	hypothetical protein	A0A2H4J832	uncultured_Caudovirales_phage	2.1e-74	95.1
WP_086874318.1\|4465974_4468362_-	DNA primase	A0A2H4JEX8	uncultured_Caudovirales_phage	0.0e+00	93.6
WP_000495504.1\|4468431_4468866_-	DUF669 domain-containing protein	Q9ZXC5	Bacillus_phage	1.7e-50	66.9
WP_061884630.1\|4468865_4469795_-	AAA family ATPase	A0A2H4JFH2	uncultured_Caudovirales_phage	1.2e-90	54.6
WP_061884631.1\|4469797_4470346_-	hypothetical protein	A0A2H4JFP8	uncultured_Caudovirales_phage	1.2e-90	92.3
WP_000588493.1\|4470323_4470605_-	hypothetical protein	A0A2H4J9A3	uncultured_Caudovirales_phage	9.7e-36	83.7
WP_001041415.1\|4470597_4470804_-	hypothetical protein	A0A1B1P7L2	Bacillus_phage	3.0e-10	49.2
WP_086874316.1\|4470897_4471245_-	hypothetical protein	A0A2H4JBP9	uncultured_Caudovirales_phage	1.5e-54	90.4
WP_086874314.1\|4471527_4471782_-	transcriptional regulator	A0A2H4JEY2	uncultured_Caudovirales_phage	1.1e-38	91.7
WP_016084484.1\|4471952_4472639_+	helix-turn-helix transcriptional regulator	A0A2H4JDE4	uncultured_Caudovirales_phage	9.4e-125	97.4
WP_086874312.1\|4472724_4474116_+	recombinase family protein	A0A2H4JFH9	uncultured_Caudovirales_phage	3.1e-244	92.7
WP_001013397.1\|4474119_4474518_-	DNA repair protein RadC	NA	NA	NA	NA
WP_001226290.1\|4474564_4475140_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_000361013.1\|4475372_4476323_-	hypothetical protein	NA	NA	NA	NA
WP_000582064.1\|4476488_4477790_-	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000072244.1\|4477883_4480529_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.2e-164	42.8
WP_000350658.1\|4481048_4482074_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_002026373.1\|4482140_4483151_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_000712934.1\|4483231_4484518_-	glutamate-1-semialdehyde 2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	1.7e-05	34.1
WP_001087052.1\|4484517_4485507_-	porphobilinogen synthase	NA	NA	NA	NA
WP_000992356.1\|4485527_4486280_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_001226421.1\|4486282_4487212_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_000007721.1\|4487227_4488061_-	cytochrome c assembly protein	NA	NA	NA	NA
WP_000547868.1\|4488078_4489413_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_000133916.1\|4489829_4490282_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000359781.1\|4490284_4490701_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_000869116.1\|4490734_4491331_-	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
WP_000097289.1\|4491327_4493658_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.2e-176	43.5
WP_000119176.1\|4493840_4495511_-\|protease	ATP-dependent protease LonB	E3T4F6	Cafeteria_roenbergensis_virus	7.4e-14	33.0
WP_000472289.1\|4495617_4496877_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.0e-148	66.3

DBSCAN-SWA_7

4543678 : 4551363

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221070.1\|4543678_4544602_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-46	44.4
WP_000247686.1\|4544726_4545662_-	HAMP domain-containing histidine kinase	Q8QNA2	Ectocarpus_siliculosus_virus	7.8e-13	26.6
WP_000018056.1\|4545663_4546356_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.0e-06	28.8
WP_001014310.1\|4546698_4546893_+	YwbE family protein	NA	NA	NA	NA
WP_001235506.1\|4546931_4548131_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	6.1e-71	41.0
WP_000587818.1\|4548426_4548750_+	heme oxygenase	NA	NA	NA	NA
WP_001086126.1\|4548822_4549587_-	class B sortase	NA	NA	NA	NA
WP_000403758.1\|4549619_4550390_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.7e-13	27.1
WP_001036832.1\|4550379_4551363_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	6.5e-18	27.5

DBSCAN-SWA_8

4938728 : 4979930

Bacillus_virus(28.57%)

protease,coat,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000614215.1\|4938728_4939730_-\|coat	spore coat protein CotS	NA	NA	NA	NA
WP_000665103.1\|4939850_4940342_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	3.5e-41	53.8
WP_000351158.1\|4940365_4940845_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001106081.1\|4941007_4942111_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_000856307.1\|4942055_4943402_+	hypothetical protein	NA	NA	NA	NA
WP_000241507.1\|4943407_4944520_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	5.2e-40	31.7
WP_000575372.1\|4944516_4945332_+	HAD hydrolase family protein	NA	NA	NA	NA
WP_000683440.1\|4945887_4946469_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_000289908.1\|4946503_4947034_-	hypothetical protein	NA	NA	NA	NA
WP_000276467.1\|4947147_4947912_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_000503345.1\|4948021_4948654_-	transcriptional regulator	NA	NA	NA	NA
WP_000274006.1\|4948734_4949175_-	DUF86 domain-containing protein	NA	NA	NA	NA
WP_000439090.1\|4949322_4950294_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000392606.1\|4950310_4950577_+	DUF3055 domain-containing protein	NA	NA	NA	NA
WP_001040868.1\|4950726_4952196_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	1.2e-65	38.8
WP_001174567.1\|4952609_4953107_+	hypothetical protein	NA	NA	NA	NA
WP_000435943.1\|4953152_4953455_-	YutD family protein	NA	NA	NA	NA
WP_000744132.1\|4953573_4954152_+	hypothetical protein	NA	NA	NA	NA
WP_000178779.1\|4954186_4954921_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_033684597.1\|4955021_4955837_+\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_001038434.1\|4955862_4956294_-	hypothetical protein	NA	NA	NA	NA
WP_000721022.1\|4956427_4956982_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_000272746.1\|4957056_4957536_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_000166372.1\|4957557_4958454_-	lipoyl synthase	NA	NA	NA	NA
WP_000944663.1\|4958643_4959627_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_033684598.1\|4959700_4960432_-	sporulation protein YunB	NA	NA	NA	NA
WP_000248466.1\|4960486_4960789_-	DUF1805 domain-containing protein	NA	NA	NA	NA
WP_073340003.1\|4960854_4962246_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_001118827.1\|4963040_4964438_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_000009523.1\|4964486_4964918_-	iron-sulfur cluster assembly scaffold protein SufU	A0A0K1LS29	Mycobacterium_phage	1.5e-14	37.6
WP_001020773.1\|4964907_4966128_-	cysteine desulfurase SufS	Q2XUY6	environmental_halophage	1.2e-117	47.4
WP_000152167.1\|4966127_4967420_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000929160.1\|4967435_4968221_-	Fe-S cluster assembly ATPase SufC	A0A285PWH2	Cedratvirus	1.3e-08	25.8
WP_000757013.1\|4968459_4969266_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000735099.1\|4969337_4970150_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000359401.1\|4970173_4970839_-	ABC transporter permease	NA	NA	NA	NA
WP_000601753.1\|4970831_4971857_-	methionine ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_001242136.1\|4972400_4972745_-	hypothetical protein	NA	NA	NA	NA
WP_000568171.1\|4972897_4973197_-	thioredoxin family protein	NA	NA	NA	NA
WP_000640870.1\|4973209_4973554_-	hypothetical protein	NA	NA	NA	NA
WP_000026897.1\|4973810_4974194_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_000218968.1\|4974235_4974601_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.1e-21	48.6
WP_000826874.1\|4975011_4975539_-	hypothetical protein	NA	NA	NA	NA
WP_000713769.1\|4975682_4976330_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000666172.1\|4976390_4977404_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_100650841.1\|4977426_4978626_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_001002981.1\|4978622_4978871_-\|coat	spore coat protein	NA	NA	NA	NA
WP_001180555.1\|4978884_4979070_-	hypothetical protein	NA	NA	NA	NA
WP_001232994.1\|4979216_4979930_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP016360

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection